The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-191424" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-191380", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-191380" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-191424", "participant_name": "MVA [cytosol]", "crossref": [ { "id": "36464", "database": "ChEBI", "url": "" }, { "id": "MEVALONATE", "database": "AraCyc", "url": "" }, { "id": "C00418", "database": "KEGG Gene", "url": "" }, { "id": "5288798", "database": "PubChem Compound", "url": "" }, { "id": "C00418", "database": "COMPOUND", "url": "" }, { "id": "3042", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000000895221", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QPP9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 391, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QPP9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QPP9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QPP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPP9" }, { "id": "PF08544", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08544" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GHMP kinase C-terminal", "eco_id": "ECO_0000259", "start_pos": 290, "end_pos": 346, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QPP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPP9" }, { "id": "PF00288", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00288" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GHMP kinase N-terminal", "eco_id": "ECO_0000259", "start_pos": 120, "end_pos": 208, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QW85-1", "uniprot_ac": "A0A5G2QW85", "uniprot_id": "A0A5G2QW85_PIG", "mass": { "chemical_mass": 41714.0, "monoisotopic_mass": 41714.0 }, "refseq": {}, "gene_names": [ { "name": "EMC2", "type": "recommended", "evidence": [ { "id": "A0A5G2QW85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85" } ] } ], "protein_names": [ { "name": "ER membrane protein complex subunit 2", "type": "recommended", "evidence": [ { "id": "A0A5G2QW85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FAA7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAA7#function" }, { "database": "UniProtKB", "id": "RU367091", "url": "https://www.uniprot.org/uniprotkb/RU367091#function" }, { "database": "UniProtKB", "id": "A0A8W4FLG2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLG2#function" }, { "database": "UniProtKB", "id": "A0A287BA71", "url": "https://www.uniprot.org/uniprotkb/A0A287BA71#function" }, { "database": "UniProtKB", "id": "A0A287BIY5", "url": "https://www.uniprot.org/uniprotkb/A0A287BIY5#function" }, { "database": "UniProtKB", "id": "A0A5G2QRH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRH8#function" }, { "database": "UniProtKB", "id": "F1S1G1", "url": "https://www.uniprot.org/uniprotkb/F1S1G1#function" }, { "database": "UniProtKB", "id": "A0A5G2QW85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85#function" }, { "database": "UniProtKB", "id": "A0A5G2QFN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFN1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EMC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85", "locus": { "chromosome": "4", "start_pos": 29017517, "end_pos": 29079270, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006032", "url": "https://www.ensembl.org/id/ENSSSCG00000006032" } ] } } ], "crossref": [ { "id": "A0A5G2QW85", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QW85", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006032", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006032", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14559", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14559", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22890", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22890", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287BA71", "url": "https://www.uniprot.org/uniprotkb/A0A287BA71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BA71-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BA71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIY5", "url": "https://www.uniprot.org/uniprotkb/A0A287BIY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BIY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW85-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAA7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLG2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1G1", "url": "https://www.uniprot.org/uniprotkb/F1S1G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1G1-1", "url": "https://www.uniprot.org/uniprotkb/F1S1G1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNGVEICHRPVAGHVTSSPRPLTPLPPGSEKMAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDALQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKTKKDNMKYASWAASQINRAYQSSCHGSAETNLRMRVQSLALLSELRILHCCELWCRLQMQFDLVLLWLWYRLAAAAQM", "length": 358, "header": "tr|A0A5G2QW85-1|A0A5G2QW85_PIG Isoform 1 of ER membrane protein complex subunit 2 OS=Sus scrofa OX=9823 GN=EMC2 PE=1 SV=2 CANONICAL=A0A5G2QW85-1" }, "isoforms": [ { "isoform_ac": "A0A287BA71-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85/entry#A0A287BA71-1", "sequence": { "sequence": "MRNGVEICHRPVAGHVTSSPRPLTPLPPGSEKMAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDALQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMFAGRSKKETKYSLKAVEDMLETLQITQS", "length": 294, "header": "tr|A0A287BA71-1|A0A5G2QW85_PIG Computationally mapped isoform of ER membrane protein complex subunit 2 OS=Sus scrofa OX=9823 GN=EMC2 PE=1 SV=1 CANONICAL=A0A5G2QW85-1" }, "locus": { "chromosome": "4", "start_pos": 29079125, "end_pos": 29028720, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059680.2", "url": "https://www.ensembl.org/id/ENSSSCT00000059680.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053438.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053438.1" } ] } }, { "isoform_ac": "A0A287BIY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85/entry#A0A287BIY5-1", "sequence": { "sequence": "MAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDALQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKTKKDNMKYASWAASQINRAYQCLAYGPFVHYICSKTF", "length": 285, "header": "tr|A0A287BIY5-1|A0A5G2QW85_PIG Computationally mapped isoform of ER membrane protein complex subunit 2 OS=Sus scrofa OX=9823 GN=EMC2 PE=1 SV=1 CANONICAL=A0A5G2QW85-1" }, "locus": { "chromosome": "4", "start_pos": 29079029, "end_pos": 29034738, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061152.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061152.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056110.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056110.2" } ] } }, { "isoform_ac": "A0A5G2QFN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85/entry#A0A5G2QFN1-1", "sequence": { "sequence": "YAKFSQLCCFLFFSEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDALQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKTKKDNMKYASWAASQINRAYQFAGRSKKETKYSLKAVEDMLETLQITQS", "length": 274, "header": "tr|A0A5G2QFN1-1|A0A5G2QFN1_PIG Computationally mapped isoform of ER membrane protein complex subunit 2 OS=Sus scrofa OX=9823 GN=EMC2 PE=1 SV=2 CANONICAL=A0A5G2QW85-1" }, "locus": { "chromosome": "4", "start_pos": 29069722, "end_pos": 29028720, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080000.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080000.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063031.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063031.2" } ] } }, { "isoform_ac": "A0A5G2QRH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85/entry#A0A5G2QRH8-1", "sequence": { "sequence": "MAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDALQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKTKKDNMKYASWAASQINRAYQFKLFVWLPQGICL", "length": 282, "header": "tr|A0A5G2QRH8-1|A0A5G2QRH8_PIG Computationally mapped isoform of ER membrane protein complex subunit 2 OS=Sus scrofa OX=9823 GN=EMC2 PE=1 SV=1 CANONICAL=A0A5G2QW85-1" }, "locus": { "chromosome": "4", "start_pos": 29079029, "end_pos": 29037636, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070509.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070509.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067524.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067524.1" } ] } }, { "isoform_ac": "A0A5G2QW85-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85/entry#A0A5G2QW85-1", "sequence": { "sequence": "MRNGVEICHRPVAGHVTSSPRPLTPLPPGSEKMAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDALQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKTKKDNMKYASWAASQINRAYQSSCHGSAETNLRMRVQSLALLSELRILHCCELWCRLQMQFDLVLLWLWYRLAAAAQM", "length": 358, "header": "tr|A0A5G2QW85-1|A0A5G2QW85_PIG Isoform 1 of ER membrane protein complex subunit 2 OS=Sus scrofa OX=9823 GN=EMC2 PE=1 SV=2 CANONICAL=A0A5G2QW85-1" }, "locus": { "chromosome": "4", "start_pos": 29079125, "end_pos": 29017520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084484.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084484.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068415.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068415.2" } ] } }, { "isoform_ac": "A0A8W4FAA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85/entry#A0A8W4FAA7-1", "sequence": { "sequence": "MRNGVEICHRPVAGHVTSSPRPLTPLPPGSEKMAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDALQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEIVFSAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMFAGRSKKETKYSLKAVEDMLETLQITQS", "length": 270, "header": "tr|A0A8W4FAA7-1|A0A5G2QW85_PIG Computationally mapped isoform of ER membrane protein complex subunit 2 OS=Sus scrofa OX=9823 GN=EMC2 PE=1 SV=1 CANONICAL=A0A5G2QW85-1" }, "locus": { "chromosome": "4", "start_pos": 29079125, "end_pos": 29028720, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093133.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093133.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076211.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076211.1" } ] } }, { "isoform_ac": "A0A8W4FLG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85/entry#A0A8W4FLG2-1", "sequence": { "sequence": "MSLGKVTAGDAGAERPKAVGSGSGISVVLRDLDSRVFSEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDALQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKTKKDNMKYASWAASQINRAYQFAGRSKKETKYSLKAVEDMLETLQITQS", "length": 322, "header": "tr|A0A8W4FLG2-1|A0A5G2QW85_PIG Computationally mapped isoform of ER membrane protein complex subunit 2 OS=Sus scrofa OX=9823 GN=EMC2 PE=1 SV=1 CANONICAL=A0A5G2QW85-1" }, "locus": { "chromosome": "4", "start_pos": 29079004, "end_pos": 29028720, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106772.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106772.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079140.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079140.1" } ] } }, { "isoform_ac": "F1S1G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85/entry#F1S1G1-1", "sequence": { "sequence": "MRNGVEICHRPVAGHVTSSPRPLTPLPPGSEKMAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDALQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMFAGRSKKETKYSLKAVEDMLETLQITQS", "length": 270, "header": "tr|F1S1G1-1|A0A5G2QW85_PIG Computationally mapped isoform of ER membrane protein complex subunit 2 OS=Sus scrofa OX=9823 GN=EMC2 PE=1 SV=4 CANONICAL=A0A5G2QW85-1" }, "locus": { "chromosome": "4", "start_pos": 29079125, "end_pos": 29028720, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006621.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006621.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006445.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006445.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FAA7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAA7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "EMC complex", "id": "GO:0072546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072546", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85" } ], "pmid": "" }, { "name": "extrinsic component of endoplasmic reticulum membrane", "id": "GO:0042406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042406", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85" } ], "pmid": "" }, { "name": "protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "id": "GO:0045050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045050", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "membrane insertase activity", "id": "GO:0032977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032977", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QW85-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 358, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QW85-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QW85" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QW85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW85" }, { "id": "PF22890", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22890" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EMC2 TPR-like", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 231, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVU2-1", "uniprot_ac": "A0A5G2QVU2", "uniprot_id": "A0A5G2QVU2_PIG", "mass": { "chemical_mass": 70441.0, "monoisotopic_mass": 70441.0 }, "refseq": {}, "gene_names": [ { "name": "NRG2", "type": "recommended", "evidence": [ { "id": "A0A5G2QVU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ] } ], "protein_names": [ { "name": "Pro-neuregulin-2, membrane-bound isoform", "type": "recommended", "evidence": [ { "id": "A0A5G2QVU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQT1#function" }, { "database": "UniProtKB", "id": "ARBA00058865", "url": "https://www.uniprot.org/uniprotkb/ARBA00058865#function" }, { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2#function" }, { "database": "UniProtKB", "id": "A0A5G2R1H6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1H6#function" }, { "database": "UniProtKB", "id": "I3LS05", "url": "https://www.uniprot.org/uniprotkb/I3LS05#function" }, { "database": "UniProtKB", "id": "A0A287BAL0", "url": "https://www.uniprot.org/uniprotkb/A0A287BAL0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NRG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2", "locus": { "chromosome": "2", "start_pos": 141662369, "end_pos": 141824727, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021082", "url": "https://www.ensembl.org/id/ENSSSCG00000021082" } ] } } ], "crossref": [ { "id": "A0A5G2QVU2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000021082", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000021082", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05750", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05750", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11100:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11100:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02158", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02158", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25518", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25518", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1227986", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1227986", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1236394", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1236394", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1250196", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1250196", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1250342", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1250342", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1250347", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1250347", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1257604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1306955", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1306955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1358803", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1358803", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1963640", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1963640", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1963642", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1963642", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6785631", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6785631", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6811558", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8847993", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8847993", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8863795", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8863795", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BAL0", "url": "https://www.uniprot.org/uniprotkb/A0A287BAL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BAL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BAL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1H6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REA4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LS05", "url": "https://www.uniprot.org/uniprotkb/I3LS05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LS05-1", "url": "https://www.uniprot.org/uniprotkb/I3LS05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEARRRGRGRGRKHREGRKREPEPGEKATRPKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTARGRLFVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLSCKCPNGFFGQRCLEKLPLRLYMPDPKQKAEELYQKRVLTITGICVALLVVGIVCVVAYCKTKKQRKQMHNHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPATDHVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSLEERRRAVGPPHHDSTDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPSSYRLAEQQPLLRHPAPGPRRGPGPGADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPPPPPRPRARGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASASDDDADDADGSLAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQDSAPL", "length": 644, "header": "tr|A0A5G2QVU2-1|A0A5G2QVU2_PIG Isoform 1 of Pro-neuregulin-2, membrane-bound isoform OS=Sus scrofa OX=9823 GN=NRG2 PE=3 SV=1 CANONICAL=A0A5G2QVU2-1" }, "isoforms": [ { "isoform_ac": "A0A287BAL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2/entry#A0A287BAL0-1", "sequence": { "sequence": "MRQVCCSALPPPPLEKARCSSYSDSSSSSSSSERSSSSSSSSESSSSRSSSSSNSSISRPAAPPEPRPQPQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCAPLERNQRYIFFLEPTEQPFVFKTAFAPLDTNGKNLKKEVGKILCTDCATRPKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTARGRLFVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLSCKCPVGYTGDRCQQFAMVNFSKHLGFELKEAEELYQKRVLTITGICVALLVVGIVCVVAYCKTKKQRKQMHNHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPATDHVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSLEERRRAVGPPHHDSTDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPSSYRLAEQQPLLRHPAPGPRRGPGPGADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPPPPPRPRARGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASASDDDADDADGSLAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQDSAPL", "length": 852, "header": "tr|A0A287BAL0-1|A0A5G2QVU2_PIG Computationally mapped isoform of Pro-neuregulin-2, membrane-bound isoform OS=Sus scrofa OX=9823 GN=NRG2 PE=3 SV=2 CANONICAL=A0A5G2QVU2-1" }, "locus": { "chromosome": "2", "start_pos": 141824530, "end_pos": 141662372, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064485.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064485.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053130.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053130.2" } ] } }, { "isoform_ac": "A0A5G2QQT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2/entry#A0A5G2QQT1-1", "sequence": { "sequence": "MRQVCCSALPPPPLEKARCSSYSDSSSSSSSSERSSSSSSSSESSSSRSSSSSNSSISRPAAPPEPRPQPQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCAPLERNQRYIFFLEPTEQPFVFKTAFAPLDTNGKNLKKEVGKILCTDCATRPKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTARGRLFVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLSCKCPVGYTGDRCQQFAMVNFSKAEELYQKRVLTITGICVALLVVGIVCVVAYCKTKKQRKQMHNHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPATDHVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSLEERRRAVGPPHHDSTDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPSSYRLAEQQPLLRHPAPGPRRGPGPGADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPPPPPRPRARGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASASDDDADDADGSLAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQDSAPL", "length": 844, "header": "tr|A0A5G2QQT1-1|A0A5G2QQT1_PIG Computationally mapped isoform of Pro-neuregulin-2, membrane-bound isoform OS=Sus scrofa OX=9823 GN=NRG2 PE=3 SV=1 CANONICAL=A0A5G2QVU2-1" }, "locus": { "chromosome": "2", "start_pos": 141824530, "end_pos": 141662372, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082741.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082741.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067272.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067272.1" } ] } }, { "isoform_ac": "A0A5G2QVU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2/entry#A0A5G2QVU2-1", "sequence": { "sequence": "MSEARRRGRGRGRKHREGRKREPEPGEKATRPKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTARGRLFVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLSCKCPNGFFGQRCLEKLPLRLYMPDPKQKAEELYQKRVLTITGICVALLVVGIVCVVAYCKTKKQRKQMHNHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPATDHVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSLEERRRAVGPPHHDSTDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPSSYRLAEQQPLLRHPAPGPRRGPGPGADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPPPPPRPRARGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASASDDDADDADGSLAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQDSAPL", "length": 644, "header": "tr|A0A5G2QVU2-1|A0A5G2QVU2_PIG Isoform 1 of Pro-neuregulin-2, membrane-bound isoform OS=Sus scrofa OX=9823 GN=NRG2 PE=3 SV=1 CANONICAL=A0A5G2QVU2-1" }, "locus": { "chromosome": "2", "start_pos": 141713118, "end_pos": 141662372, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076968.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076968.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068265.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068265.1" } ] } }, { "isoform_ac": "A0A5G2R1H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2/entry#A0A5G2R1H6-1", "sequence": { "sequence": "MRQVCCSALPPPPLEKARCSSYSDSSSSSSSSERSSSSSSSSESSSSRSSSSSNSSISRPAAPPEPRPQPQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCAPLERNQRYIFFLEPTEQPFVFKTAFAPLDTNGKNLKKEVGKILCTDCATRPKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTARGRLFVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLSCKCPNGFFGQRCLEKLPLRLYMPDPKQKHLGFELKEAEELYQKRVLTITGICVALLVVGIVCVVAYCKTKKQRKQMHNHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPATDHVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSLEERRRAVGPPHHDSTDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPSSYRLAEQQPLLRHPAPGPRRGPGPGADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPPPPPRPRARGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASASDDDADDADGSLAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQDSAPL", "length": 858, "header": "tr|A0A5G2R1H6-1|A0A5G2R1H6_PIG Computationally mapped isoform of Pro-neuregulin-2, membrane-bound isoform OS=Sus scrofa OX=9823 GN=NRG2 PE=3 SV=1 CANONICAL=A0A5G2QVU2-1" }, "locus": { "chromosome": "2", "start_pos": 141824530, "end_pos": 141662372, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070655.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070655.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068052.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068052.1" } ] } }, { "isoform_ac": "A0A5G2REA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2/entry#A0A5G2REA4-1", "sequence": { "sequence": "MRQVCCSALPPPPLEKARCSSYSDSSSSSSSSERSSSSSSSSESSSSRSSSSSNSSISRPAAPPEPRPQPQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCAPLERNQRYIFFLEPTEQPFVFKTAFAPLDTNGKNLKKEVGKILCTDCATRPKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTARGRLFVNSEAEELYQKRVLTITGICVALLVVGIVCVVAYCKTKKQRKQMHNHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPATDHVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSLEERRRAVGPPHHDSTDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPSSYRLAEQQPLLRHPAPGPRRGPGPGADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPPPPPRPRARGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASASDDDADDADGSLAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQDSAPL", "length": 784, "header": "tr|A0A5G2REA4-1|A0A5G2REA4_PIG Computationally mapped isoform of Neuregulin 2 OS=Sus scrofa OX=9823 GN=NRG2 PE=4 SV=1 CANONICAL=A0A5G2QVU2-1" }, "locus": { "chromosome": "2", "start_pos": 141824530, "end_pos": 141662372, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080322.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080322.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069172.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069172.1" } ] } }, { "isoform_ac": "I3LS05-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2/entry#I3LS05-1", "sequence": { "sequence": "MRQVCCSALPPPPLEKARCSSYSDSSSSSSSSERSSSSSSSSESSSSRSSSSSNSSISRPAAPPEPRPQPQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCAPLERNQRYIFFLEPTEQPFVFKTAFAPLDTNGKNLKKEVGKILCTDCATRPKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTARGRLFVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLSCKCPNGFFGQRCLEKLPLRLYMPDPKQKAEELYQKRVLTITGICVALLVVGIVCVVAYCKTKKQRKQMHNHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPATDHVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSLEERRRAVGPPHHDSTDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPSSYRLAEQQPLLRHPAPGPRRGPGPGADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPPPPPRPRARGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASASDDDADDADGSLAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQDSAPL", "length": 850, "header": "tr|I3LS05-1|A0A5G2QVU2_PIG Computationally mapped isoform of Pro-neuregulin-2, membrane-bound isoform OS=Sus scrofa OX=9823 GN=NRG2 PE=3 SV=3 CANONICAL=A0A5G2QVU2-1" }, "locus": { "chromosome": "2", "start_pos": 141824530, "end_pos": 141662372, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025683.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025683.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026896.3", "url": "https://www.ensembl.org/id/ENSSSCP00000026896.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LS05", "url": "https://www.uniprot.org/uniprotkb/I3LS05" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1227986", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1227986", "resource": "Reactome", "description": "Signaling by ERBB2" }, { "id": "R-SSC-1236394", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1236394", "resource": "Reactome", "description": "Signaling by ERBB4" }, { "id": "R-SSC-1250196", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1250196", "resource": "Reactome", "description": "SHC1 events in ERBB2 signaling" }, { "id": "R-SSC-1250342", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1250342", "resource": "Reactome", "description": "PI3K events in ERBB4 signaling" }, { "id": "R-SSC-1250347", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1250347", "resource": "Reactome", "description": "SHC1 events in ERBB4 signaling" }, { "id": "R-SSC-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-SSC-1306955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1306955", "resource": "Reactome", "description": "GRB7 events in ERBB2 signaling" }, { "id": "R-SSC-1358803", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1358803", "resource": "Reactome", "description": "Downregulation of ERBB2:ERBB3 signaling" }, { "id": "R-SSC-1963640", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1963640", "resource": "Reactome", "description": "GRB2 events in ERBB2 signaling" }, { "id": "R-SSC-1963642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1963642", "resource": "Reactome", "description": "PI3K events in ERBB2 signaling" }, { "id": "R-SSC-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-SSC-6785631", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6785631", "resource": "Reactome", "description": "ERBB2 Regulates Cell Motility" }, { "id": "R-SSC-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" }, { "id": "R-SSC-8847993", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8847993", "resource": "Reactome", "description": "ERBB2 Activates PTK6 Signaling" }, { "id": "R-SSC-8863795", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8863795", "resource": "Reactome", "description": "Downregulation of ERBB2 signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ], "pmid": "" }, { "name": "ERBB4 signaling pathway", "id": "GO:0038130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038130", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVU2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 644, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVU2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVU2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 177, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QVU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 127, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 246, "end_pos": 248 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QUB4-1", "uniprot_ac": "A0A5G2QUB4", "uniprot_id": "A0A5G2QUB4_PIG", "mass": { "chemical_mass": 34102.0, "monoisotopic_mass": 34102.0 }, "refseq": {}, "gene_names": [ { "name": "FYTTD1", "type": "recommended", "evidence": [ { "id": "A0A5G2QUB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4" } ] } ], "protein_names": [ { "name": "UAP56-interacting factor", "type": "recommended", "evidence": [ { "id": "A0A5G2QUB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4/entry#names_and_taxonomy" } ] }, { "name": "Forty-two-three domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A5G2QUB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FYTTD1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4", "locus": { "chromosome": "13", "start_pos": 134402630, "end_pos": 134363682, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027139", "url": "https://www.ensembl.org/id/ENSSSCG00000027139" } ] } } ], "crossref": [ { "id": "A0A5G2QUB4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUB4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000027139", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027139", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR009782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21038", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21038", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21038:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21038:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72187", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72187", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BKE6", "url": "https://www.uniprot.org/uniprotkb/A0A287BKE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BKE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BKE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TP46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TP46-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPSWIHFCCTMTGTLDDDIIKLNRKEGKKQNFPRLNRRLQQSGTRQFRMRVRWGIQQNSGFGKNSLSRRGRVMPGKRRPYGIITGLAARKATGIRKGISPMNRPPLSDKNIERYFPALKRKANLLRQNEVQRKPVAVLKRPNQLNRKNNIPANFTRSGNKLSHQKDTRQATFLFRRGLKVQAQLNTEQLLDDVVAKRTRQWRTSTTNGGILTVSIDNPGAVQCPVTQKPRLTRTAVPSFLTKREQSDVKKVPKGVPLQFDINSVGKQTGMTLNERFGILKEQRATLTFNKGGSRFVTVG", "length": 300, "header": "tr|A0A5G2QUB4-1|A0A5G2QUB4_PIG Isoform 1 of UAP56-interacting factor OS=Sus scrofa OX=9823 GN=FYTTD1 PE=1 SV=2 CANONICAL=A0A5G2QUB4-1" }, "isoforms": [ { "isoform_ac": "A0A287BKE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4/entry#A0A287BKE6-1", "sequence": { "sequence": "MNRFGTRLMGAAATPPPPPKARSNENLDKIDMSLGFGKNSLSRRGRVMPGKRRPYGIITGLAARKATGIRKGISPMNRPPLSDKNIERYFPALKRKANLLRQNEVQRKPVAVLKRPNQLNRKTQKPRLTRTAVPSFLTKREQSDVKKVPKGVPLQFDINSVGKQTGMTLNERFGILKEQRATLTFNKGGSRFVTVG", "length": 196, "header": "tr|A0A287BKE6-1|A0A5G2QUB4_PIG Computationally mapped isoform of UAP56-interacting factor OS=Sus scrofa OX=9823 GN=FYTTD1 PE=1 SV=2 CANONICAL=A0A5G2QUB4-1" }, "locus": { "chromosome": "13", "start_pos": 134398881, "end_pos": 134363782, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050530.2", "url": "https://www.ensembl.org/id/ENSSSCT00000050530.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056547.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056547.2" } ] } }, { "isoform_ac": "A0A4X1TP46-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4/entry#A0A4X1TP46-1", "sequence": { "sequence": "MNRFGTRLMGAAATPPPPPKARSNENLDKIDMSLGFGKNSLSRRGRVMPGKRRPYGIITGLAARKATGIRKGISPMNRPPLSDKNIERYFPALKRKANLLRQNEVQRKPVAVLKRPNQLNRKNNIPANFTRSGNKLSHQKDTRQATFLFRRGLKVQAQLNTEQLLDDVVAKRTRQWRTSTTNGGILTVSIDNPGAVQCPVTQKPRLTRTAVPSFLTKREQSDVKKVPKGVPLQFDINSVGKQTGMTLNERFGILKEQRATLTFNKGGSRFVTVG", "length": 274, "header": "tr|A0A4X1TP46-1|A0A4X1TP46_PIG Computationally mapped isoform of UAP56-interacting factor OS=Sus scrofa OX=9823 GN=FYTTD1 PE=1 SV=1 CANONICAL=A0A5G2QUB4-1" }, "locus": { "chromosome": "13", "start_pos": 134398881, "end_pos": 134363782, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082933.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082933.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071488.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071488.1" } ] } }, { "isoform_ac": "A0A5G2QUB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4/entry#A0A5G2QUB4-1", "sequence": { "sequence": "MVPSWIHFCCTMTGTLDDDIIKLNRKEGKKQNFPRLNRRLQQSGTRQFRMRVRWGIQQNSGFGKNSLSRRGRVMPGKRRPYGIITGLAARKATGIRKGISPMNRPPLSDKNIERYFPALKRKANLLRQNEVQRKPVAVLKRPNQLNRKNNIPANFTRSGNKLSHQKDTRQATFLFRRGLKVQAQLNTEQLLDDVVAKRTRQWRTSTTNGGILTVSIDNPGAVQCPVTQKPRLTRTAVPSFLTKREQSDVKKVPKGVPLQFDINSVGKQTGMTLNERFGILKEQRATLTFNKGGSRFVTVG", "length": 300, "header": "tr|A0A5G2QUB4-1|A0A5G2QUB4_PIG Isoform 1 of UAP56-interacting factor OS=Sus scrofa OX=9823 GN=FYTTD1 PE=1 SV=2 CANONICAL=A0A5G2QUB4-1" }, "locus": { "chromosome": "13", "start_pos": 134398881, "end_pos": 134367336, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076393.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076393.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061730.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061730.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 298, "start_aa": "Thr", "end_pos": 298, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr298", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BKE6", "url": "https://www.uniprot.org/uniprotkb/A0A287BKE6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-SSC-72187", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72187", "resource": "Reactome", "description": "mRNA 3'-end processing" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QUB4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 300, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QUB4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUB4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 298 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQI4-1", "uniprot_ac": "A0A5G2QQI4", "uniprot_id": "A0A5G2QQI4_PIG", "mass": { "chemical_mass": 35872.0, "monoisotopic_mass": 35872.0 }, "refseq": {}, "gene_names": [ { "name": "UBLCP1", "type": "recommended", "evidence": [ { "id": "A0A5G2QQI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4" } ] } ], "protein_names": [ { "name": "Ubiquitin-like domain-containing CTD phosphatase 1", "type": "recommended", "evidence": [ { "id": "A0A5G2QQI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "A0A5G2QQI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4/entry#names_and_taxonomy" } ] }, { "name": "Nuclear proteasome inhibitor UBLCP1", "type": "synonym", "evidence": [ { "id": "A0A5G2QQI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. Recruited to the 19S regulatory particle of the 26S proteasome through its interaction with 19S component PSMD2/RPN1. Once recruited, dephosphorylates 19S component PSMC2/RPT1 which impairs PSMC2 ATPase activity and disrupts 26S proteasome assembly. Has also been reported to stimulate the proteolytic activity of the 26S proteasome.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BNL3", "url": "https://www.uniprot.org/uniprotkb/A0A287BNL3#function" }, { "database": "UniProtKB", "id": "ARBA00046190", "url": "https://www.uniprot.org/uniprotkb/ARBA00046190#function" }, { "database": "UniProtKB", "id": "A0A4X1U0U3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0U3#function" }, { "database": "UniProtKB", "id": "A0A5G2QQI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UBLCP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4", "locus": { "chromosome": "16", "start_pos": 64178941, "end_pos": 64205675, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017042", "url": "https://www.ensembl.org/id/ENSSSCG00000017042" } ] } } ], "crossref": [ { "id": "A0A5G2QQI4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017042", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017042", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01813", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01813", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519748", "url": "https://www.ncbi.nlm.nih.gov/gene/100519748", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004274", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004274", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519748", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519748", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TVHTPKY", "url": "https://omabrowser.org/oma/group/TVHTPKY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287BNL3", "url": "https://www.orthodb.org/?gene=A0A287BNL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48493", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48493", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48493:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48493:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BNL3", "url": "https://www.uniprot.org/uniprotkb/A0A287BNL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BNL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BNL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U0U3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U0U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0U3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLGPPPDNDDVVNDFDIEDEVVEVENREENLLKISRRVKEYKVEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAKLDDFLDLNHKYWER", "length": 310, "header": "tr|A0A5G2QQI4-1|A0A5G2QQI4_PIG Isoform 1 of Ubiquitin-like domain-containing CTD phosphatase 1 OS=Sus scrofa OX=9823 GN=UBLCP1 PE=1 SV=1 CANONICAL=A0A5G2QQI4-1" }, "isoforms": [ { "isoform_ac": "A0A287BNL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4/entry#A0A287BNL3-1", "sequence": { "sequence": "MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLGPPPDNDDVVNDFDIEDEVVEVENREENLLKISRRVKEYKVEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAKLDDFLDLNHKYWERYLSKKQGQ", "length": 318, "header": "tr|A0A287BNL3-1|A0A5G2QQI4_PIG Computationally mapped isoform of Ubiquitin-like domain-containing CTD phosphatase 1 OS=Sus scrofa OX=9823 GN=UBLCP1 PE=1 SV=1 CANONICAL=A0A5G2QQI4-1" }, "locus": { "chromosome": "16", "start_pos": 64201737, "end_pos": 64183953, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050578.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050578.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058206.1", "url": "https://www.ensembl.org/id/ENSSSCP00000058206.1" } ] } }, { "isoform_ac": "A0A4X1U0U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4/entry#A0A4X1U0U3-1", "sequence": { "sequence": "MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLGPPPDNDDVVNDFDIEDEVVEVENREENLLKISRRVKEYKVEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDIRPFMKAHLNRDKDKELLKLTQYLKEIAKLDDFLDLNHKYWERYLSKKQGQ", "length": 279, "header": "tr|A0A4X1U0U3-1|A0A4X1U0U3_PIG Computationally mapped isoform of Ubiquitin-like domain-containing CTD phosphatase 1 OS=Sus scrofa OX=9823 GN=UBLCP1 PE=1 SV=1 CANONICAL=A0A5G2QQI4-1" }, "locus": { "chromosome": "16", "start_pos": 64201737, "end_pos": 64183953, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018555.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018555.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018055.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018055.3" } ] } }, { "isoform_ac": "A0A5G2QQI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4/entry#A0A5G2QQI4-1", "sequence": { "sequence": "MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLGPPPDNDDVVNDFDIEDEVVEVENREENLLKISRRVKEYKVEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAKLDDFLDLNHKYWER", "length": 310, "header": "tr|A0A5G2QQI4-1|A0A5G2QQI4_PIG Isoform 1 of Ubiquitin-like domain-containing CTD phosphatase 1 OS=Sus scrofa OX=9823 GN=UBLCP1 PE=1 SV=1 CANONICAL=A0A5G2QQI4-1" }, "locus": { "chromosome": "16", "start_pos": 64201737, "end_pos": 64185730, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084298.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084298.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066992.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066992.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BNL3", "url": "https://www.uniprot.org/uniprotkb/A0A287BNL3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519748", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519748", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q2KJD7-1", "protein_name": "Ubiquitin-like domain-containing CTD phosphatase 1", "gene_name": "UBLCP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLGPPPDNDDVVNDFDIEDEVVEVENREENLLKISRRVKEYKVEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAKLDDFLDLNHKYWERYLSKKQGQ", "length": 318 }, "evidence": [ { "id": "A0A5G2QQI4", "url": "https://omabrowser.org/oma/group/A0A5G2QQI4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q556S4-1", "protein_name": "protein-serine/threonine phosphatase", "gene_name": "ublcp1-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDTIVSSSTTNPPTTTESTINSIITTTDSNSNNTNDNTTTNTTTTTTTTTTTNIINDSDLKTKTTTTTTTIINEENSKITIKTKWNGKEYKVLISKSSTVFDLKRQLETMTNVLSKRQKILGLSKGKQPTDEMIIESLSIQDNHSIIMMGTPESNIIADVPKTSGDTDEVFNDFEFDYIPDSDEISHIEKNKNQLLAMIERSNDISLINDPRPNKKLLVLDLDHTILDFKDQDVENMKRPHLEEFLVQSYQHYDIGIWSQTSWKWIEIKLTELGLLTNPRFKICFVMDQTLMFKVTTYRTINGKERTKIKHNVKALEVIWKHQHLGKFFSMKNTLHVDDLSKNFAMNPKNGVHVPPFKIKDAKKYGDNVLFHLTKYLKSISNEEDITLIDHKEWIRKIL", "length": 399 }, "evidence": [ { "id": "A0A5G2QQI4", "url": "https://omabrowser.org/oma/group/A0A5G2QQI4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5FWT7-1", "protein_name": "Ubiquitin-like domain-containing CTD phosphatase 1", "gene_name": "Ublcp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLCPPPDNDDVINDFDIEDEVVEVENREENLLKISRRVKEYKVEVLNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELVKLTQYLKEIAKLDDFLELNHKYWERYLSKKQGQ", "length": 318 }, "evidence": [ { "id": "A0A5G2QQI4", "url": "https://omabrowser.org/oma/group/A0A5G2QQI4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5ZJJ8-1", "protein_name": "Ubiquitin-like domain-containing CTD phosphatase 1", "gene_name": "UBLCP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSLSLIIKWGGQEYTITSLSEEDTVLDLKQSLKGLTGVLPERQKLLGLKMKGKPADDDVKLGALKLKPNTKIMMMGTREESLEDVLGPPPDNDDVINDFDIEEEVVEVENREENLLKISRRVKEYKVEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEYYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAKLDDFLELNHKHWERYLSKKQGQ", "length": 318 }, "evidence": [ { "id": "A0A5G2QQI4", "url": "https://omabrowser.org/oma/group/A0A5G2QQI4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6DI37-1", "protein_name": "Ubiquitin-like domain-containing CTD phosphatase 1", "gene_name": "ublcp1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVSVIIKWGGQEYSINTLSEEDTVLDLKQSIKSLTGVLPERQKLLGLKLKGKPADDNVKLGDLKLKPNTKIMMMGTREESLEDVLAPPPENDDVVNDFDIEEEVTEVENREENLAKIARRVKDYKVEELNPPRPGKRLLVLDIDYTLFDHKSCAETGHELMRPFLHEFLTSAYEDFDIVIWSATSMKWIDAKMKELGVTDNPNYKITFMLDSAAMITVHTPKRGVVEVKPLGVIWGKYSEFYNRKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNREKDKELYKLSQYLKEIAKLDDFSGLNHKHWERYLSKKQNQ", "length": 318 }, "evidence": [ { "id": "A0A5G2QQI4", "url": "https://omabrowser.org/oma/group/A0A5G2QQI4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BGR9-1", "protein_name": "Ubiquitin-like domain-containing CTD phosphatase 1", "gene_name": "Ublcp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLCPPPDNDDVINDFDIEDEVVEVENREENLLKVSRRVKEYKVEVLNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELVKLTQYLKEIAKLDDFLELNHKYWERYLSKKQGQ", "length": 318 }, "evidence": [ { "id": "A0A5G2QQI4", "url": "https://omabrowser.org/oma/group/A0A5G2QQI4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8W3M6-1", "protein_name": "Ubiquitin-like domain-containing CTD phosphatase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASSSSSPTPSAAAAVSPLTEEELTLTVKWNGKEYTVRICADDSVAELKRRICLLTTVLPKRQKLLYPKIGNKLSDDSLLLSSISFKPSLKMTMIGTVEDDIIVDQAESPEIVDDFELGKEEAVDVKDKEVNKQKLRRRIDQYKINLRTPCRQGKKLLVLDIDYTLFDHRSTAENPLQLMRPYLHEFLTAAYAEYDIMIWSATSMKWVELKMTELGVLNNPNYKVTALLDHLAMITVQSDTRGIFDCKPLGLIWALLPEFYNPGNTIMFDDLRRNFVMNPQNGLTIKPFRKAHANRDTDQELVKLTQYLLTIAELSDLSSLHHSRWESFSQDNVKRRRQE", "length": 340 }, "evidence": [ { "id": "A0A5G2QQI4", "url": "https://omabrowser.org/oma/group/A0A5G2QQI4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8WVY7-1", "protein_name": "Ubiquitin-like domain-containing CTD phosphatase 1", "gene_name": "UBLCP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLGPPPDNDDVVNDFDIEDEVVEVENREENLLKISRRVKEYKVEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAKLDDFLDLNHKYWERYLSKKQGQ", "length": 318 }, "evidence": [ { "id": "A0A5G2QQI4", "url": "https://omabrowser.org/oma/group/A0A5G2QQI4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9XZ16-1", "protein_name": "Ubiquitin-like domain-containing CTD phosphatase 1", "gene_name": "Ublcp1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEVKEVVVIVKWSGKEYPVDLTDQDTVEVLRHEIFRKTQVRPERQKLLNLKYKGKTAADNVKISALELKPNFKLMMVGSTEADIEDACSLPDNIGEVVDDFDDADEREESVEHSAVYLAKVQRRVRDYKIKELAPPREGKKLLVLDIDYTLFDHRSPAETGTELMRPYLHEFLTSAYEDYDIVIWSATSMRWIEEKMRLLGVASNDNYKVMFYLDSTAMISVHVPERGVVDVKPLGVIWALYKQYNSSNTIMFDDIRRNFLMNPKSGLKIRPFRQAHLNRGTDTELLKLSDYLRKIAHHCPDFNSLNHRKWEHYHPKKNS", "length": 320 }, "evidence": [ { "id": "A0A5G2QQI4", "url": "https://omabrowser.org/oma/group/A0A5G2QQI4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4" } ], "pmid": "" }, { "name": "proteasome regulatory particle binding", "id": "GO:1904855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904855", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of proteasome assembly", "id": "GO:0090364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090364", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQI4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQI4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQI4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4" }, { "id": "PS50969", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50969" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FCP1 homology", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 294, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QQI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI4" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 81, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQF7-1", "uniprot_ac": "A0A5G2QQF7", "uniprot_id": "A0A5G2QQF7_PIG", "mass": { "chemical_mass": 22481.0, "monoisotopic_mass": 22481.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "FXYD domain-containing ion transport regulator", "type": "recommended", "evidence": [ { "id": "A0A5G2QQF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7", "locus": {} } ], "crossref": [ { "id": "A0A5G2QQF7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQF7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015083", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015083", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047297", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047297", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14132:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14132:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5578775", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5578775", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-936837", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-936837", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BQ23", "url": "https://www.uniprot.org/uniprotkb/A0A287BQ23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BQ23-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BQ23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KRIPPAPGSRGSALGAAGDGQHGDGERVRVQTLPGGQRTVTPRSPEPSWDETPPTSPHPCRTRHSSPSSPSWEGRRKKGKASPIALPPAPPLPGSSGLGTSSWDCLRRGPRCADAMEVLLMFLCSLLAPAVLASAAEQEKEKDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCTFNQKPRALGDEEAQVENLVTANATEPQKAEN", "length": 210, "header": "tr|A0A5G2QQF7-1|A0A5G2QQF7_PIG Isoform 1 of FXYD domain-containing ion transport regulator OS=Sus scrofa OX=9823 GN= PE=1 SV=1 CANONICAL=A0A5G2QQF7-1" }, "isoforms": [ { "isoform_ac": "A0A287BQ23-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7/entry#A0A287BQ23-1", "sequence": { "sequence": "MWEKSSPIRRCQEYTCPYAMEVLLMFLCSLLAPAVLASAAEQEKEKDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCTFNQKPRALGDEEAQVENLVTANATEPQKAEN", "length": 114, "header": "tr|A0A287BQ23-1|A0A5G2QQF7_PIG Computationally mapped isoform of FXYD domain-containing ion transport regulator OS=Sus scrofa OX=9823 GN= PE=1 SV=3 CANONICAL=A0A5G2QQF7-1" }, "locus": { "chromosome": "9", "start_pos": 45212111, "end_pos": 45186562, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057720.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057720.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058530.3", "url": "https://www.ensembl.org/id/ENSSSCP00000058530.3" } ] } }, { "isoform_ac": "A0A5G2QQF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7/entry#A0A5G2QQF7-1", "sequence": { "sequence": "KRIPPAPGSRGSALGAAGDGQHGDGERVRVQTLPGGQRTVTPRSPEPSWDETPPTSPHPCRTRHSSPSSPSWEGRRKKGKASPIALPPAPPLPGSSGLGTSSWDCLRRGPRCADAMEVLLMFLCSLLAPAVLASAAEQEKEKDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCTFNQKPRALGDEEAQVENLVTANATEPQKAEN", "length": 210, "header": "tr|A0A5G2QQF7-1|A0A5G2QQF7_PIG Isoform 1 of FXYD domain-containing ion transport regulator OS=Sus scrofa OX=9823 GN= PE=1 SV=1 CANONICAL=A0A5G2QQF7-1" }, "locus": { "chromosome": "9", "start_pos": 45218085, "end_pos": 45186562, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083493.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083493.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067132.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067132.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 41, "start_aa": "Thr", "end_pos": 41, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr41", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BQ23", "url": "https://www.uniprot.org/uniprotkb/A0A287BQ23" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5578775", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5578775", "resource": "Reactome", "description": "Ion homeostasis" }, { "id": "R-SSC-936837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-936837", "resource": "Reactome", "description": "Ion transport by P-type ATPases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7" } ], "pmid": "" }, { "name": "regulation of monoatomic ion transport", "id": "GO:0043269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043269", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7" } ], "pmid": "" }, { "name": "positive regulation of sodium ion export across plasma membrane", "id": "GO:1903278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903278", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ion channel regulator activity", "id": "GO:0099106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099106", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7" } ], "pmid": "" }, { "name": "sodium channel regulator activity", "id": "GO:0017080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017080", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQF7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 210, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQF7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQF7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 41 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QT44-1", "uniprot_ac": "A0A5G2QT44", "uniprot_id": "A0A5G2QT44_PIG", "mass": { "chemical_mass": 64681.0, "monoisotopic_mass": 64681.0 }, "refseq": { "ac": "XP_020928801", "name": "paxillin isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928801" }, "gene_names": [ { "name": "PXN", "type": "recommended", "evidence": [ { "id": "A0A5G2QT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" } ] }, { "name": "PXN", "type": "synonym", "evidence": [ { "id": "XP_020928801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928801" } ] } ], "protein_names": [ { "name": "Paxillin", "type": "recommended", "evidence": [ { "id": "A0A5G2QT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44/entry#names_and_taxonomy" } ] }, { "name": "paxillin isoform X6", "type": "synonym", "evidence": [ { "id": "XP_020928801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928801" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PXN", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44", "locus": { "chromosome": "14", "start_pos": 40227895, "end_pos": 40278734, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040546", "url": "https://www.ensembl.org/id/ENSSSCG00000040546" } ] } } ], "crossref": [ { "id": "A0A5G2QT44", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QT44", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000040546", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000040546", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09336", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09336", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09338", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09338", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09409", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09409", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09411", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09411", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110256718", "url": "https://www.ncbi.nlm.nih.gov/gene/110256718", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24216:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24216:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-180292", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-180292", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4420097", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4420097", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-445355", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-445355", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-446343", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446343", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-446388", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446388", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8849471", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8849471", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020928801", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928801", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BTJ4", "url": "https://www.uniprot.org/uniprotkb/A0A287BTJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BTJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BTJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QT44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QT44-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTN6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG25-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGSVLDPIDQWQPSTSRFIHQQPQAPSPVYGSSAKTSSSSNPQDGIGLPCPRASEEEHVYSFPNKQKSAEPSPTVMSSSLGSNLSELDRLLLELNAVQHNAPGFPTDEANSSPPLPGALSPHYGVLEHNSSLGGKAGPVTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITLNQGEMNSPQRVTSSQQQTRISASSATRELDELMASLSDFKTQGLEQRVDRELCWAAGWRNGRQSSPEGQDKGGFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC", "length": 590, "header": "tr|A0A5G2QT44-1|A0A5G2QT44_PIG Isoform 1 of Paxillin OS=Sus scrofa OX=9823 GN=PXN PE=3 SV=1 CANONICAL=A0A5G2QT44-1" }, "isoforms": [ { "isoform_ac": "A0A287BTJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44/entry#A0A287BTJ4-1", "sequence": { "sequence": "KWDLVVPRPLPSTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGSVLDPIDQWQPSTSRFIHQQPQAPSPVYGSSAKTSSSSNPQDGIGLPCPRASEEEHVYSFPNKQKSAEPSPTVMSSSLGSNLSELDRLLLELNAVQHNAPGFPTDEANSSPPLPGALSPHYGVLEHNSSLGGKAGPVTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITLNQGEMNSPQRVTSSQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC", "length": 556, "header": "tr|A0A287BTJ4-1|A0A5G2QT44_PIG Computationally mapped isoform of Paxillin OS=Sus scrofa OX=9823 GN=PXN PE=3 SV=2 CANONICAL=A0A5G2QT44-1" }, "locus": { "chromosome": "14", "start_pos": 40240389, "end_pos": 40229758, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056618.2", "url": "https://www.ensembl.org/id/ENSSSCT00000056618.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059556.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059556.2" } ] } }, { "isoform_ac": "A0A5G2QT44-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44/entry#A0A5G2QT44-1", "sequence": { "sequence": "MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGSVLDPIDQWQPSTSRFIHQQPQAPSPVYGSSAKTSSSSNPQDGIGLPCPRASEEEHVYSFPNKQKSAEPSPTVMSSSLGSNLSELDRLLLELNAVQHNAPGFPTDEANSSPPLPGALSPHYGVLEHNSSLGGKAGPVTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITLNQGEMNSPQRVTSSQQQTRISASSATRELDELMASLSDFKTQGLEQRVDRELCWAAGWRNGRQSSPEGQDKGGFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC", "length": 590, "header": "tr|A0A5G2QT44-1|A0A5G2QT44_PIG Isoform 1 of Paxillin OS=Sus scrofa OX=9823 GN=PXN PE=3 SV=1 CANONICAL=A0A5G2QT44-1" }, "locus": { "chromosome": "14", "start_pos": 40278626, "end_pos": 40229758, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076770.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076770.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068003.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068003.1" } ] } }, { "isoform_ac": "A0A5G2QTN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44/entry#A0A5G2QTN6-1", "sequence": { "sequence": "MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGSVLDPIDQWQPSTSRFIHQQPQAPSPVYGSSAKTSSSSNPQDGIGLPCPRASEEEHVYSFPNKQKSAEPSPTVMSSSLGSNLSELDRLLLELNAVQHNAPGFPTDEANSSPPLPGALSPHYGVLEHNSSLGGKAGPVTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITLNQGEMNSPQRVTSSQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC", "length": 557, "header": "tr|A0A5G2QTN6-1|A0A5G2QTN6_PIG Computationally mapped isoform of Paxillin OS=Sus scrofa OX=9823 GN=PXN PE=3 SV=1 CANONICAL=A0A5G2QT44-1" }, "locus": { "chromosome": "14", "start_pos": 40278626, "end_pos": 40229758, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088367.1", "url": "https://www.ensembl.org/id/ENSSSCT00000088367.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061515.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061515.1" } ] } }, { "isoform_ac": "A0A5G2RG25-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44/entry#A0A5G2RG25-1", "sequence": { "sequence": "MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGSVLDPIDQWQPSTSRFIHQQPQAPSPVYGSSAKTSSSSNPQDGIGLPCPRASEEEHVYSFPNKQKSAEPSPTVMSSSLGSNLSELDRLLLELNAVQHNAPGFPTDEANSSPPLPGALSPHYGVLEHNSSLGGKAGPVTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITLNQGEMNSPQRVTSSQQQTRISASSATRELDELMASLSDFKTSSSAVALSSPGLLSSSAPSTHCFLPPPSPPRPSVFLPPAGKPPTRGPGHTPEVVCTEDSDNLAQGLVPPVAPSWLDLAGFGVTPDTPNSRSSSMEGSLGPLGTESQAHIWRDPPNLVCELSRASPGNILPHTGCIGPQESGDPQLPSANPLCQGEAMAAMQGLLWGLEVVRSKTPQGAMPSFQQVSEPTLVAADRQAVFPDTWSLPKERGQQERARPGPGEQLGGETPMGGSLVRPIQGLKTPRTPEGTTETAAEARREQLELPQAVVMDTPNTTERISTSGQIRSVIRRSRETGHAHPMSREPSPRRRLDPATLSRTPSQERLIAELQGRLGIQPEVEEATEASAEDWLTEGVIITVQPRGRRAGGQLVEKVVFPPGSPIPLRRTFSVLPSPPPPSPLLQHRRDTSASSSSPPPSPPGPSTLGSPALPCASPGVQSTGVGPWEADAQGPSPFSPAPHSLSSVGCQTDEDPLFPPMQTQGLEQRVDRELCWAAGWRNGRQSSPEGQDKGGFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC", "length": 1068, "header": "tr|A0A5G2RG25-1|A0A5G2RG25_PIG Computationally mapped isoform of Paxillin OS=Sus scrofa OX=9823 GN=PXN PE=3 SV=1 CANONICAL=A0A5G2QT44-1" }, "locus": { "chromosome": "14", "start_pos": 40278626, "end_pos": 40229758, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089030.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089030.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070084.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070084.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BTJ4", "url": "https://www.uniprot.org/uniprotkb/A0A287BTJ4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-180292", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-180292", "resource": "Reactome", "description": "GAB1 signalosome" }, { "id": "R-SSC-4420097", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4420097", "resource": "Reactome", "description": "VEGFA-VEGFR2 Pathway" }, { "id": "R-SSC-445355", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-445355", "resource": "Reactome", "description": "Smooth Muscle Contraction" }, { "id": "R-SSC-446343", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446343", "resource": "Reactome", "description": "Localization of the PINCH-ILK-PARVIN complex to focal adhesions" }, { "id": "R-SSC-446388", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446388", "resource": "Reactome", "description": "Regulation of cytoskeletal remodeling and cell spreading by IPP complex components" }, { "id": "R-SSC-8849471", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8849471", "resource": "Reactome", "description": "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" } ], "pmid": "" }, { "name": "endothelial cell migration", "id": "GO:0043542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043542", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QT44-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 590, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QT44-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QT44" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT44" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 355, "end_pos": 414, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 168, "end_pos": 170 }, { "start_pos": 187, "end_pos": 189 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRS2-1", "uniprot_ac": "A0A5G2QRS2", "uniprot_id": "A0A5G2QRS2_PIG", "mass": { "chemical_mass": 96876.0, "monoisotopic_mass": 96876.0 }, "refseq": {}, "gene_names": [ { "name": "ADGRD1", "type": "recommended", "evidence": [ { "id": "A0A5G2QRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2" } ] } ], "protein_names": [ { "name": "Adhesion G-protein coupled receptor D1", "type": "recommended", "evidence": [ { "id": "A0A5G2QRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 133", "type": "synonym", "evidence": [ { "id": "A0A5G2QRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Adhesion G-protein coupled receptor (aGPCR) for androgen hormone 5alpha-dihydrotestosterone (5alpha-DHT), also named 17beta-hydroxy-5alpha-androstan-3-one, the most potent hormone among androgens. Also activated by methenolone drug. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRD1 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Acts as a 5alpha-DHT receptor in muscle cells, thereby increasing intracellular cyclic AMP (cAMP) levels and enhancing muscle strength.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2#function" }, { "database": "UniProtKB", "id": "ARBA00093338", "url": "https://www.uniprot.org/uniprotkb/ARBA00093338#function" }, { "database": "UniProtKB", "id": "F1RFQ8", "url": "https://www.uniprot.org/uniprotkb/F1RFQ8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ADGRD1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2", "locus": { "chromosome": "14", "start_pos": 24059019, "end_pos": 24241176, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009745", "url": "https://www.ensembl.org/id/ENSSSCG00000009745" } ] } } ], "crossref": [ { "id": "A0A5G2QRS2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRS2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009745", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009745", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011:SF216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011:SF216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1URS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1URS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1URS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1URS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QJN6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QJN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QJN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QJN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RFQ8", "url": "https://www.uniprot.org/uniprotkb/F1RFQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RFQ8-1", "url": "https://www.uniprot.org/uniprotkb/F1RFQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKLLPLCCWHSWLLLFYCDFQVHGADARSQAHPGFEVLASASYYWPLENVDGIHELQETTGDIVEGKVNKGIYLKGEKGITLLYFGEYKPSCIFNPAQCSPEGVTFSFFWKIQGEQSRSAPFAYGGQVISNLFKVCSRGGKGSVELYTHDNSMTWEATFSPPGPYWTHVLFTWKFKEGLKVYVNGTLSNSDPSGKEAHAYGEPNANLVIGSEQDQTKRYDNGAFDEFIIWERALTPDEIAMYFTAAVGKHVLLSSASPNFFMTPTANTMVPTDAYHPIITNLTEERKNFQSPGIVLNYLQNVSLSLPNKFLSEETALNLTKTFLKAMGEVLHLPSWSAVSEDGTMVLGLIETVEAVMSHISSNLQPREAHVTIVGSSSMADFSVARLLPKTLNSSHYRFPARGQNYIEIPHVAFHSQAWTTIVGLLYHSMHYYLSHIQPADTRIAEATKYKNCLLSATSYLISLEASPSPKLSQNLSGSPLITIRLRHHLTQRQYIEATNESNRIFLYCAFLDFSSGEGVWSNQGCGLVEGNLSYSVCRCTHLTNFAILMQVVPLELTHGHQVALSSISYIGCSLSVLCLAVTLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLVSFQFEPGTTPCQVLAVFLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGIGWGFPLLICIISQFAMDSYGTSKNCWLSLGSGAIWAFVAPALFIIVVNIGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWLFGVLAVNSEAVVFQYMFAILNSLQGFFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSTRQANMKPFSSDIMNGTRPGTGSSRLSPWDKSSHSAHRVDLSAV", "length": 873, "header": "tr|A0A5G2QRS2-1|A0A5G2QRS2_PIG Isoform 1 of Adhesion G-protein coupled receptor D1 OS=Sus scrofa OX=9823 GN=ADGRD1 PE=3 SV=1 CANONICAL=A0A5G2QRS2-1" }, "isoforms": [ { "isoform_ac": "A0A4X1URS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2/entry#A0A4X1URS4-1", "sequence": { "sequence": "MQVVPLEVNIGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWLFGVLAVNSEAVVFQYMFAILNSLQGFFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSTRQANMKPFSSDIMNGTRPGTGSSRLSPWDKSSHSAHRVDLSAV", "length": 156, "header": "tr|A0A4X1URS4-1|A0A4X1URS4_PIG Computationally mapped isoform of Adhesion G protein-coupled receptor D1 OS=Sus scrofa OX=9823 GN=ADGRD1 PE=4 SV=1 CANONICAL=A0A5G2QRS2-1" }, "locus": { "chromosome": "14", "start_pos": 24119324, "end_pos": 24061803, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075566.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075566.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062963.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062963.1" } ] } }, { "isoform_ac": "A0A5G2QJN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2/entry#A0A5G2QJN6-1", "sequence": { "sequence": "MPEGGWHQVCLNLRSPSACPGAGQRVAGFDVLLETKPWDGWLSFLRSTDVGSQKAVCRWSKFKTCLLLLLETDQCGGRCRVDSDVLQVRRRRSPVLLLVQVNIGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWLFGVLAVNSEAVVFQYMFAILNSLQGFFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSTRQANMKPFSSDIPAGTKGSFSLSSSAPAVDLLQVH", "length": 241, "header": "tr|A0A5G2QJN6-1|A0A5G2QRS2_PIG Computationally mapped isoform of Adhesion G-protein coupled receptor D1 OS=Sus scrofa OX=9823 GN=ADGRD1 PE=3 SV=1 CANONICAL=A0A5G2QRS2-1" }, "locus": { "chromosome": "14", "start_pos": 24071213, "end_pos": 24063069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086157.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086157.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062262.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062262.1" } ] } }, { "isoform_ac": "A0A5G2QRS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2/entry#A0A5G2QRS2-1", "sequence": { "sequence": "MRKLLPLCCWHSWLLLFYCDFQVHGADARSQAHPGFEVLASASYYWPLENVDGIHELQETTGDIVEGKVNKGIYLKGEKGITLLYFGEYKPSCIFNPAQCSPEGVTFSFFWKIQGEQSRSAPFAYGGQVISNLFKVCSRGGKGSVELYTHDNSMTWEATFSPPGPYWTHVLFTWKFKEGLKVYVNGTLSNSDPSGKEAHAYGEPNANLVIGSEQDQTKRYDNGAFDEFIIWERALTPDEIAMYFTAAVGKHVLLSSASPNFFMTPTANTMVPTDAYHPIITNLTEERKNFQSPGIVLNYLQNVSLSLPNKFLSEETALNLTKTFLKAMGEVLHLPSWSAVSEDGTMVLGLIETVEAVMSHISSNLQPREAHVTIVGSSSMADFSVARLLPKTLNSSHYRFPARGQNYIEIPHVAFHSQAWTTIVGLLYHSMHYYLSHIQPADTRIAEATKYKNCLLSATSYLISLEASPSPKLSQNLSGSPLITIRLRHHLTQRQYIEATNESNRIFLYCAFLDFSSGEGVWSNQGCGLVEGNLSYSVCRCTHLTNFAILMQVVPLELTHGHQVALSSISYIGCSLSVLCLAVTLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLVSFQFEPGTTPCQVLAVFLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGIGWGFPLLICIISQFAMDSYGTSKNCWLSLGSGAIWAFVAPALFIIVVNIGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWLFGVLAVNSEAVVFQYMFAILNSLQGFFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSTRQANMKPFSSDIMNGTRPGTGSSRLSPWDKSSHSAHRVDLSAV", "length": 873, "header": "tr|A0A5G2QRS2-1|A0A5G2QRS2_PIG Isoform 1 of Adhesion G-protein coupled receptor D1 OS=Sus scrofa OX=9823 GN=ADGRD1 PE=3 SV=1 CANONICAL=A0A5G2QRS2-1" }, "locus": { "chromosome": "14", "start_pos": 24240642, "end_pos": 24061803, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071549.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071549.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064727.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064727.1" } ] } }, { "isoform_ac": "F1RFQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2/entry#F1RFQ8-1", "sequence": { "sequence": "MRKLLPLCCWHSWLLLFYCDFQVHGADARSQAHPGFEVLASASYYWPLENVDGIHELQETTGALRTHNLTVLPSHNSTFVYTNGSAYSNFSATVDIVEGKVNKGIYLKGEKGITLLYFGEYKPSCIFNPAQCSPEGVTFSFFWKIQGEQSRSAPFAYGGQVISNLFKVCSRGGKGSVELYTHDNSMTWEATFSPPGPYWTHVLFTWKFKEGLKVYVNGTLSNSDPSGKEAHAYGEPNANLVIGSEQDQTKRYDNGAFDEFIIWERALTPDEIAMYFTAAVGKHVLLSSASPNFFMTPTANTMVPTDAYHPIITNLTEERKNFQSPGIVLNYLQNVSLSLPNKFLSEETALNLTKTFLKAMGEVLHLPSWSAVSEDGTMVLGLIETVEAVMSHISSNLQPREAHVTIVGSSSMADFSVARLLPKTLNSSHYRFPARGQNYIEIPHVAFHSQAWTTIVGLLYHSMHYYLSHIQPADTRIAEATKYKNCLLSATSYLISLEASPSPKLSQNLSGSPLITIRLRHHLTQRQYIEATNESNRIFLYCAFLDFSSGEGVWSNQGCGLVEGNLSYSVCRCTHLTNFAILMQVVPLELTHGHQVALSSISYIGCSLSVLCLAVTLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLVSFQFEPGTTPCQVLAVFLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGIGWGFPLLICIISQFAMDSYGTSKNCWLSLGSGAIWAFVAPALFIIVVNIGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWLFGVLAVNSEAVVFQYMFAILNSLQGFFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSTRQANMKPFSSDIMNGTRPGTGSSRLSPWDKSSHSAHRVDLSAV", "length": 905, "header": "tr|F1RFQ8-1|A0A5G2QRS2_PIG Computationally mapped isoform of Adhesion G-protein coupled receptor D1 OS=Sus scrofa OX=9823 GN=ADGRD1 PE=3 SV=4 CANONICAL=A0A5G2QRS2-1" }, "locus": { "chromosome": "14", "start_pos": 24240642, "end_pos": 24061803, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010684.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010684.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010407.5", "url": "https://www.ensembl.org/id/ENSSSCP00000010407.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QJN6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QJN6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2" } ], "pmid": "" }, { "name": "regulation of skeletal muscle contraction", "id": "GO:0014819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014819", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRS2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 873, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRS2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRS2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2" }, { "id": "PS50261", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 2", "eco_id": "ECO_0000259", "start_pos": 566, "end_pos": 809, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2" }, { "id": "PS50221", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50221" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GAIN-B", "eco_id": "ECO_0000259", "start_pos": 371, "end_pos": 557, "start_aa": "His", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS2" }, { "id": "PS51828", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51828" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pentraxin (PTX)", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 276, "start_aa": "Lys", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 476, "end_pos": 478 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 533, "end_pos": 535 }, { "start_pos": 607, "end_pos": 609 }, { "start_pos": 844, "end_pos": 846 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1P5-1", "uniprot_ac": "A0A287B1P5", "uniprot_id": "A0A287B1P5_PIG", "mass": { "chemical_mass": 27262.0, "monoisotopic_mass": 27262.0 }, "refseq": { "ac": "NP_001230431", "name": "protein GUCD1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230431" }, "gene_names": [ { "name": "GUCD1", "type": "recommended", "evidence": [ { "id": "A0A287B1P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1P5" } ] }, { "name": "C14H22orf13", "type": "synonym", "evidence": [ { "id": "NP_001230431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230431" } ] }, { "name": "GUCD1", "type": "synonym", "evidence": [ { "id": "NP_001230431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230431" } ] } ], "protein_names": [ { "name": "Guanylyl cyclase domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A287B1P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1P5/entry#names_and_taxonomy" } ] }, { "name": "protein GUCD1", "type": "synonym", "evidence": [ { "id": "NP_001230431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230431" } ] }, { "name": "uncharacterized protein C22orf13", "type": "synonym", "evidence": [ { "id": "NP_001230431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230431" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1P5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1P5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GUCD1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1P5", "locus": { "chromosome": "14", "start_pos": 49572822, "end_pos": 49585057, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010059", "url": "https://www.ensembl.org/id/ENSSSCG00000010059" } ] } } ], "crossref": [ { "id": "ENSSSCG00000010059", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010059", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100154708", "url": "https://www.ncbi.nlm.nih.gov/gene/100154708", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018616", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018616", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154708", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154708", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQDIQKH", "url": "https://omabrowser.org/oma/group/VQDIQKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287B1P5", "url": "https://www.orthodb.org/?gene=A0A287B1P5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31400", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31400", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31400:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31400:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001230431", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230431", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A1F7", "url": "https://www.uniprot.org/uniprotkb/A0A287A1F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1F7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1P5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNG6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RL42", "url": "https://www.uniprot.org/uniprotkb/F1RL42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RL42-1", "url": "https://www.uniprot.org/uniprotkb/F1RL42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTEGEASGPPLEPGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDSEFESALQELRLTRSIWTIDLAYLMRHFGVRHRFCTQTLGVDKGYKNQSFYRKHFDTEETRVNQLFAQAKACKVLVEKRTVSVQDIQAHLAQGHVAIVLVNSGVLHCDLCSSPVKYCCFAPSGHRCFCRSPDYQGHFIVLRGYNRATSCIFYNNPAYADRMCSTSISNFEEARTSYGTDEDILFVYLDS", "length": 239, "header": "tr|A0A287B1P5-1|A0A287B1P5_PIG Isoform 1 of Guanylyl cyclase domain containing 1 OS=Sus scrofa OX=9823 GN=GUCD1 PE=4 SV=1 CANONICAL=A0A287B1P5-1" }, "isoforms": [ { "isoform_ac": "A0A287A1F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1P5/entry#A0A287A1F7-1", "sequence": { "sequence": "MGAPRRPRHEDGGGGIGAAARARYLGQLDDSEFESALQELRLTRSIWTIDLAYLMRHFGVRHRFCTQTLGVDKGYKNQSFYRKHFDTEETRVNQLFAQAKACKVLVEKRTVSVQDIQAHLAQGHVAIVLVNSGVLHCDLCSSPVKYCCFAPSGHRCFCRSPDYQGHFIVLRGYNRATSCIFYNNPAYADRMCSTSISNFEEARTSYGTDEDILFVYLDS", "length": 219, "header": "tr|A0A287A1F7-1|A0A287B1P5_PIG Computationally mapped isoform of Guanylyl cyclase domain containing 1 OS=Sus scrofa OX=9823 GN=GUCD1 PE=4 SV=3 CANONICAL=A0A287B1P5-1" }, "locus": { "chromosome": "14", "start_pos": 49584912, "end_pos": 49574968, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054121.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054121.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037586.3", "url": "https://www.ensembl.org/id/ENSSSCP00000037586.3" } ] } }, { "isoform_ac": "A0A287B1P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1P5/entry#A0A287B1P5-1", "sequence": { "sequence": "MRTEGEASGPPLEPGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDSEFESALQELRLTRSIWTIDLAYLMRHFGVRHRFCTQTLGVDKGYKNQSFYRKHFDTEETRVNQLFAQAKACKVLVEKRTVSVQDIQAHLAQGHVAIVLVNSGVLHCDLCSSPVKYCCFAPSGHRCFCRSPDYQGHFIVLRGYNRATSCIFYNNPAYADRMCSTSISNFEEARTSYGTDEDILFVYLDS", "length": 239, "header": "tr|A0A287B1P5-1|A0A287B1P5_PIG Isoform 1 of Guanylyl cyclase domain containing 1 OS=Sus scrofa OX=9823 GN=GUCD1 PE=4 SV=1 CANONICAL=A0A287B1P5-1" }, "locus": { "chromosome": "14", "start_pos": 49584887, "end_pos": 49574968, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042062.2", "url": "https://www.ensembl.org/id/ENSSSCT00000042062.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050353.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050353.1" } ] } }, { "isoform_ac": "A0A5G2QNG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1P5/entry#A0A5G2QNG6-1", "sequence": { "sequence": "MRTEGEASGPPLEPGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDSEFESALQELRLTRSIWTIDLAYLMRHFGVRHRFCTQTLGVDKGYKNQSFYRKHFDTEETRVNQLFAQAKACKVLVEKRRNVQHQHQ", "length": 137, "header": "tr|A0A5G2QNG6-1|A0A287B1P5_PIG Computationally mapped isoform of Guanylyl cyclase domain containing 1 OS=Sus scrofa OX=9823 GN=GUCD1 PE=4 SV=1 CANONICAL=A0A287B1P5-1" }, "locus": { "chromosome": "14", "start_pos": 49584887, "end_pos": 49575035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084860.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084860.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066224.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066224.1" } ] } }, { "isoform_ac": "F1RL42-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1P5/entry#F1RL42-1", "sequence": { "sequence": "MMEDGAFQGHRSSESGCPALGYLGQLDDSEFESALQELRLTRSIWTIDLAYLMRHFGVRHRFCTQTLGVDKGYKNQSFYRKHFDTEETRVNQLFAQAKACKVLVEKRTVSVQDIQAHLAQGHVAIVLVNSGVLHCDLCSSPVKYCCFAPSGHRCFCRSPDYQGHFIVLRGYNRATSCIFYNNPAYADRMCSTSISNFEEARTSYGTDEDILFVYLDS", "length": 217, "header": "tr|F1RL42-1|A0A287B1P5_PIG Computationally mapped isoform of Guanylyl cyclase domain containing 1 OS=Sus scrofa OX=9823 GN=GUCD1 PE=4 SV=4 CANONICAL=A0A287B1P5-1" }, "locus": { "chromosome": "14", "start_pos": 49579589, "end_pos": 49574968, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011020.4", "url": "https://www.ensembl.org/id/ENSSSCT00000011020.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010732.4", "url": "https://www.ensembl.org/id/ENSSSCP00000010732.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QNG6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNG6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154708", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154708", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ASP6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "Gucd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGAGFQRPDLEGIRRGLRRPRHRLPGSEPRWPRRRRRRNSTLTGRALRPAEIAAAISSRPGPWAPCATRVMRTEVEAAGQPLEPEDFVQLPVPTIQQLYHWDCGLACSRMVLRYLGQLDDREFENALQELQLTRSIWTIDLAYLMRHFGVRHRFCTQTLGVDKGYKNQSFYRKHFDTEETRVNQLFAQAKACKVQVEKCTVSVQDIQAHLAQGHVAIVLVNSGVLHCELCSSPVKYCCFTPRGHRCFCRAPDYQGHFIVLRGYNRATGCIFYNNPAYADRMCSTSISNFEEARTSYGTDEDILFVYLDS", "length": 310 }, "evidence": [ { "id": "A0A287B1P5", "url": "https://omabrowser.org/oma/group/A0A287B1P5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1A8C8-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVPPHSWPSRGQLPPSQLRAAAPGPAPSAAGRSQRRIRARRGPGPGGAGSERAAAAMRSPREPGEPPPQAVECVQLKVPIIQQLYHWDCGLACSRMVLQYLDHLDNDEFQKAIQELRLTKSIWTIDLAYLMRHFGVKHKFCTQTLGVDKGYKNQSFYRKHFDTEENRVNQLFAQAKASKVLVEKCTVTVQDIQKHLSQGHVAIVLVNAVLLLCDLCSSPVKYCCFLPIGQKCFCRNPDYQGHFIVLCGYNTASGSIYYNNPAYADRTCCTSIRNFEEARRSYGTDEDILFIYTDS", "length": 295 }, "evidence": [ { "id": "A0A287B1P5", "url": "https://omabrowser.org/oma/group/A0A287B1P5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HY22-1", "protein_name": "Protein GUCD1 isoform X3", "gene_name": "Gucd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLRYLGQLDDGEFQNALQELQLTRSIWTIDLAYLMRHFGVRHRFCTQTLGVDKGYKNQSFYRKHFDTEETRVNQLFAQAKACKVRVEKCTVSVQDIQAHLAQGHVAIVLVNSGVLHCDLCSSPVKYCCFTPSGHRCFCRTPDYQGHFIVLRGYNRATGCIFYNNPAYADRMCSTSISNFEEARTSYGTDEDILFVYLDS", "length": 200 }, "evidence": [ { "id": "A0A287B1P5", "url": "https://omabrowser.org/oma/group/A0A287B1P5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BZI6-1", "protein_name": "Protein GUCD1", "gene_name": "Gucd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRTEAEAAGQPLEPGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDGEFENALQELQLTRSIWTIDLAYLMRHFGVRHRFCTQTLGVDKGYKNQSFYRKHFDTEETRVNQLFAQAKACKVQVEKCTVSVQDIQVHLAQGHVAIVLVNSGVLHCDLCSSPVKYCCFTPSGHRCFCRTPDYQGHFIVLRGYNRATGCIFYNNPAYADRMCSTSISNFEEARTSYGTDEDILFVYLDS", "length": 239 }, "evidence": [ { "id": "A0A287B1P5", "url": "https://omabrowser.org/oma/group/A0A287B1P5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8L870-1", "protein_name": "Guanylyl cyclase 1", "gene_name": "GC1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MWPLCFLLNKLLRVEERNQGILDGNGDSTFPKYCLFDDPLVSDGKYRDAGLPSSSHMDVPHVHQLASWDCGLACVLMVLRASGIASCTLEDLAEICSTNSIWTVDLAYLLQKFCVEFSYYTITFGANPNYSIEEFYKEQLPEDLVRVDLLFRKAHESGIIIQCRSVSIHEISCLLLSGNYIAIALVDQDKLSKSWLEEVLVSGLHSSNSCYTGHYVVICGYDAVRDEFEIRDPASSKIHERISSKCLENARKSFGTDEDLLLINLENMRNQNGY", "length": 274 }, "evidence": [ { "id": "A0A287B1P5", "url": "https://omabrowser.org/oma/group/A0A287B1P5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96NT3-1", "protein_name": "Protein GUCD1", "gene_name": "GUCD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTEAEAAGPPLEPGDFVQLPVPVIQQLYHWDCGLACSRMVLRYLGQLDDSEFERALQKLQLTRSIWTIDLAYLMHHFGVRHRFCTQTLGVDKGYKNQSFYRKHFDTEETRVNQLFAQAKACKVLVEKCTVSVKDIQAHLAQGHVAIVLVNSGVLHCDLCSSPVKYCCFTPSGHHCFCRTPDYQGHFIVLRGYNRATGCIFYNNPAYADPGMCSTSISNFEEARTSYGTDEDILFVYLDS", "length": 240 }, "evidence": [ { "id": "A0A287B1P5", "url": "https://omabrowser.org/oma/group/A0A287B1P5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W4Y0-1", "protein_name": "Protein GUCD1", "gene_name": "EG:BACR25B3.6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNGLPPSKHYNLTHYQQRYNWDCGLSCIIMILSAQQREQLLGNFDAVCGEEGFGSSTWTIDLCYLLMRYQVRHEYFTQTLGIDPNYAQHTYYSKIIDKDERRVTRKFKDARAHGLRVEQRTVDMEVILRHLARHGPVILLTNASLLTCEVCKRNVLEKFGCFHIPCIAQNTRLHGPKRYAGHYVVLCGYDMAAQKLFYHNPEVHDGHICRCLIESMDTARRAYGTDEDIIFIYEKKETRE", "length": 240 }, "evidence": [ { "id": "A0A287B1P5", "url": "https://omabrowser.org/oma/group/A0A287B1P5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1G7-1", "uniprot_ac": "A0A287B1G7", "uniprot_id": "A0A287B1G7_PIG", "mass": { "chemical_mass": 34643.0, "monoisotopic_mass": 34643.0 }, "refseq": { "ac": "XP_003126052", "name": "peroxisomal membrane protein PMP34", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126052" }, "gene_names": [ { "name": "SLC25A17", "type": "recommended", "evidence": [ { "id": "A0A287B1G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ] }, { "name": "SLC25A17", "type": "synonym", "evidence": [ { "id": "XP_003126052", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126052" } ] } ], "protein_names": [ { "name": "Peroxisomal membrane protein PMP34", "type": "recommended", "evidence": [ { "id": "A0A287B1G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7/entry#names_and_taxonomy" } ] }, { "name": "34 kDa peroxisomal membrane protein", "type": "synonym", "evidence": [ { "id": "A0A287B1G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 25 member 17", "type": "synonym", "evidence": [ { "id": "A0A287B1G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7/entry#names_and_taxonomy" } ] }, { "name": "peroxisomal membrane protein PMP34", "type": "synonym", "evidence": [ { "id": "XP_003126052", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126052" } ] } ], "function": [ { "annotation": "Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extent for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3',5'-diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter-exchange mechanism.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7#function" }, { "database": "UniProtKB", "id": "ARBA00060197", "url": "https://www.uniprot.org/uniprotkb/ARBA00060197#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC25A17", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7", "locus": { "chromosome": "5", "start_pos": 7670283, "end_pos": 7622646, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000072", "url": "https://www.ensembl.org/id/ENSSSCG00000000072" } ] } } ], "crossref": [ { "id": "A0A287B1G7", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1G7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000072", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000072", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100517713", "url": "https://www.ncbi.nlm.nih.gov/gene/100517713", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517713", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517713", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFMMYEL", "url": "https://omabrowser.org/oma/group/QFMMYEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287B1G7", "url": "https://www.orthodb.org/?gene=A0A287B1G7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45939:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45939:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-389599", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-389599", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9603798", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9603798", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003126052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126052", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "65424", "url": "https://www.rhea-db.org/rhea/65424", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72839", "url": "https://www.rhea-db.org/rhea/72839", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72847", "url": "https://www.rhea-db.org/rhea/72847", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72851", "url": "https://www.rhea-db.org/rhea/72851", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73087", "url": "https://www.rhea-db.org/rhea/73087", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73091", "url": "https://www.rhea-db.org/rhea/73091", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73095", "url": "https://www.rhea-db.org/rhea/73095", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73099", "url": "https://www.rhea-db.org/rhea/73099", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73143", "url": "https://www.rhea-db.org/rhea/73143", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73147", "url": "https://www.rhea-db.org/rhea/73147", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73151", "url": "https://www.rhea-db.org/rhea/73151", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73155", "url": "https://www.rhea-db.org/rhea/73155", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73159", "url": "https://www.rhea-db.org/rhea/73159", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73163", "url": "https://www.rhea-db.org/rhea/73163", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73167", "url": "https://www.rhea-db.org/rhea/73167", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73171", "url": "https://www.rhea-db.org/rhea/73171", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73175", "url": "https://www.rhea-db.org/rhea/73175", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73183", "url": "https://www.rhea-db.org/rhea/73183", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73447", "url": "https://www.rhea-db.org/rhea/73447", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73451", "url": "https://www.rhea-db.org/rhea/73451", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A606", "url": "https://www.uniprot.org/uniprotkb/A0A287A606", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A606-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A606-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AH37", "url": "https://www.uniprot.org/uniprotkb/A0A287AH37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AH37-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AH37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SRB8", "url": "https://www.uniprot.org/uniprotkb/F1SRB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SRB8-1", "url": "https://www.uniprot.org/uniprotkb/F1SRB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASVLSYENLVHAVAGAVGSMTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKTVWVKGQHSTTGKDLIVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYSGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAIAKAIATTVTYPMQTVQSILRFGRHRLNPENRTLGSLRNVLYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTATTFMVMGLKRASKH", "length": 307, "header": "tr|A0A287B1G7-1|A0A287B1G7_PIG Isoform 1 of Peroxisomal membrane protein PMP34 OS=Sus scrofa OX=9823 GN=SLC25A17 PE=3 SV=1 CANONICAL=A0A287B1G7-1" }, "isoforms": [ { "isoform_ac": "A0A287A606-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7/entry#A0A287A606-1", "sequence": { "sequence": "MASVLSYENLVHAVAGAVGSMTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKTVWVKGQHSTTGKDLIVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYSGIIAFLFGCVHHWCDSQSHCHHGHLSHADSTVNSEVWTSQTKPRKQNTGESSERSLSSAPTSEAFWNNGTLQRP", "length": 221, "header": "tr|A0A287A606-1|A0A287B1G7_PIG Computationally mapped isoform of Peroxisomal membrane protein PMP34 OS=Sus scrofa OX=9823 GN=SLC25A17 PE=3 SV=1 CANONICAL=A0A287B1G7-1" }, "locus": { "chromosome": "5", "start_pos": 7669171, "end_pos": 7622780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050054.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050054.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039249.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039249.2" } ] } }, { "isoform_ac": "A0A287AH37-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7/entry#A0A287AH37-1", "sequence": { "sequence": "MASVLSYENLVHAVAGAVGSMTAMTVFFPLDTARLRLQGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYSGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAIAKAIATTVTYPMQTVQSILRFGRHRLNPENRTLGSLRNVLYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTATTFMVMGLKRASKH", "length": 234, "header": "tr|A0A287AH37-1|A0A287B1G7_PIG Computationally mapped isoform of Peroxisomal membrane protein PMP34 OS=Sus scrofa OX=9823 GN=SLC25A17 PE=3 SV=1 CANONICAL=A0A287B1G7-1" }, "locus": { "chromosome": "5", "start_pos": 7669283, "end_pos": 7622780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046906.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046906.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043188.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043188.1" } ] } }, { "isoform_ac": "A0A287B1G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7/entry#A0A287B1G7-1", "sequence": { "sequence": "MASVLSYENLVHAVAGAVGSMTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKTVWVKGQHSTTGKDLIVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYSGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAIAKAIATTVTYPMQTVQSILRFGRHRLNPENRTLGSLRNVLYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTATTFMVMGLKRASKH", "length": 307, "header": "tr|A0A287B1G7-1|A0A287B1G7_PIG Isoform 1 of Peroxisomal membrane protein PMP34 OS=Sus scrofa OX=9823 GN=SLC25A17 PE=3 SV=1 CANONICAL=A0A287B1G7-1" }, "locus": { "chromosome": "5", "start_pos": 7669283, "end_pos": 7622780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054524.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054524.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050005.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050005.1" } ] } }, { "isoform_ac": "F1SRB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7/entry#F1SRB8-1", "sequence": { "sequence": "CFGGGGLERVEFLTLPLGAPVLLSSLDWLWLLLENCDQVCGNRTYGFRAVLRKPGPRRGRSRGKHDGNDGIFSLGHGSTSTSSLAPYRGWFPVISSLCCSNFVYFYTFNSLKTVWVKGQHSTTGKDLIVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYSGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAIAKAIATTVTYPMQTVQSILRFGRHRLNPENRTLGSLRNVLYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTATTFMVMGLKRASKH", "length": 329, "header": "tr|F1SRB8-1|F1SRB8_PIG Computationally mapped isoform of Solute carrier family 25 member 17 OS=Sus scrofa OX=9823 GN=SLC25A17 PE=3 SV=4 CANONICAL=A0A287B1G7-1" }, "locus": { "chromosome": "5", "start_pos": 7669283, "end_pos": 7622647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000078.5", "url": "https://www.ensembl.org/id/ENSSSCT00000000078.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000077.4", "url": "https://www.ensembl.org/id/ENSSSCP00000000077.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A606", "url": "https://www.uniprot.org/uniprotkb/A0A287A606" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517713", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517713", "resource": "KEGG Pathway" }, { "id": "R-SSC-389599", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-389599", "resource": "Reactome", "description": "Alpha-oxidation of phytanate" }, { "id": "R-SSC-9603798", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9603798", "resource": "Reactome", "description": "Class I peroxisomal membrane protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YPL7-1", "protein_name": "Solute carrier family 25 member 17", "gene_name": "SLC25A17", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSLGRKFLKLEEVKIQTGMNSEPPREDKSRRSQKRASEQMVDTYKCLGKQVNIKGSVTAMTVFFPLDTARLRLQVDEKRKSKTTPAVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKTLWVKGQHSSTGKDLVLGVVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGALALWNGTFPSLLLVFNPAIQFMFYEGFKRKLLKKQTQLTSLDAFVMGAVAKAVATTLTYPLQTVQSILRFGRHRLNPENRTLGSLKNVLYLLRERVRRFGLMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFRVMGLKHSRAH", "length": 343 }, "evidence": [ { "id": "A0A287B1G7", "url": "https://omabrowser.org/oma/group/A0A287B1G7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3IGY2-1", "protein_name": "Peroxisomal membrane protein PMP34", "gene_name": "Slc25a17", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHAVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKTVWVKGQRSSTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIIPTNYKGIIDAFHQIIRDEGILALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAIAKAIATTVTYPMQTVQSILRFGRHRLNPENRTLGSLRNVLYLLHQRVKRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKSTHKH", "length": 307 }, "evidence": [ { "id": "A0A287B1G7", "url": "https://omabrowser.org/oma/group/A0A287B1G7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O04200-1", "protein_name": "Peroxisomal nicotinamide adenine dinucleotide carrier", "gene_name": "PXN", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSDALINGLAGAGGGIIAQLLTYPLQTVNTRQQTERDLKREKRKLGTIEHMCQVVKQEGWERLYGGLAPSLAGTAASQGVYYYFYQVFRNRAEATALARKKKGLGDGSVGMFASLLVAAFAGSVNVLMTNPIWVIVTRMQTHRKMTKDQTAAPESPSSNAEALVAVEPRPYGTFNTIREVYDEAGITGFWKGVIPTLIMVSNPSMQFMLYETMLTKLKKKRALKGSNNVTALETFLLGAVAKLGATVTTYPLLVVKSRLQAKQVTTGDKRQQYKGTLDAILKMIRYEGLYGFYKGMSTKIVQSVLAAAVLFMIKEELVKGAKLLLSNATSS", "length": 331 }, "evidence": [ { "id": "A0A287B1G7", "url": "https://omabrowser.org/oma/group/A0A287B1G7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O43808-1", "protein_name": "Peroxisomal membrane protein PMP34", "gene_name": "SLC25A17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHSTTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPENRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKRAHQH", "length": 307 }, "evidence": [ { "id": "A0A287B1G7", "url": "https://omabrowser.org/oma/group/A0A287B1G7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70579-1", "protein_name": "Peroxisomal membrane protein PMP34", "gene_name": "Slc25a17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHAVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKAVWVKGQRSSTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIIPTNYKGIIDAFHQIIRDEGILALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAIAKAIATTVTYPMQTVQSILRFGRHRLNPENRTLGSLRNVLSLLHQRVKRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKSTHKH", "length": 307 }, "evidence": [ { "id": "A0A287B1G7", "url": "https://omabrowser.org/oma/group/A0A287B1G7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q76P23-1", "protein_name": "Mitochondrial substrate carrier family protein Q", "gene_name": "mcfQ", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSEKIHITQNSGNVDHTVEALGHAISGGVAGMAAIALTYPFSTVSTRLQVQQKKQQQGQQSEITTVPYKNSIDAFKRIIKEENWRTLYSGLKSALIGIGASSFVYYYWYTLLKSISLKLKNKQELGTIENLAIAALAGCANVLTTLPIWVVNTRLQINSDKGIVGQFKYIIKNEGFGGLYKGLIPALILVSNPSVQFVSYEKLRALWRRQSGRTKLGGLEVFILGAIAKLIAGIVTYPYLLVKSRLQSQSGNASNPESQQQQYKGTLDAIGKIFKSDGFLGFFKGMPSKMVQTVIGAAFMFLVKDKVVIHAVAILFYLKRLLNKNNKRV", "length": 329 }, "evidence": [ { "id": "A0A287B1G7", "url": "https://omabrowser.org/oma/group/A0A287B1G7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VZD9-1", "protein_name": "Peroxisomal membrane protein 34, isoform A", "gene_name": "PMP34", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVAPSKLSQVLSYQNFVHAVSGAAGGCIAMSTFYPLDTVRSRLQLEEAGDVRSTRQVIKEIVLGEGFQSLYRGLGPVLQSLCISNFVYFYTFHALKAVASGGSPSQHSALKDLLLGSIAGIINVLTTTPFWVVNTRLRMRNVAGTSDEVNKHYKNLLEGLKYVAEKEGIAGLWSGTIPSLMLVSNPALQFMMYEMLKRNIMRFTGGEMGSLSFFFIGAIAKAFATVLTYPLQLVQTKQRHRSKESDSKPSTSAGSTPRTESTLELMISILQHQGIRGLFRGLEAKILQTVLTAALMFMAYEKIAGTVGMLLKRN", "length": 314 }, "evidence": [ { "id": "A0A287B1G7", "url": "https://omabrowser.org/oma/group/A0A287B1G7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "pmid": "" }, { "name": "ATP transmembrane transporter activity", "id": "GO:0005347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005347", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "pmid": "" }, { "name": "ADP transmembrane transporter activity", "id": "GO:0015217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015217", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "pmid": "" }, { "name": "coenzyme A transmembrane transporter activity", "id": "GO:0015228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015228", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "pmid": "" }, { "name": "FMN transmembrane transporter activity", "id": "GO:0044610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044610", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "pmid": "" }, { "name": "NAD transmembrane transporter activity", "id": "GO:0051724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051724", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "pmid": "" }, { "name": "AMP transmembrane transporter activity", "id": "GO:0080122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080122", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "pmid": "" }, { "name": "FAD transmembrane transporter activity", "id": "GO:0015230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015230", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "pmid": "" }, { "name": "fatty acid transport", "id": "GO:0015908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015908", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "65424", "name": "", "equation": "AMP(in) + NAD(+)(out) = AMP(out) + NAD(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "65424", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/65424" } ] }, { "id": "72839", "name": "", "equation": "ADP(out) + CoA(in) = ADP(in) + CoA(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72839", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72839" } ] }, { "id": "72847", "name": "", "equation": "adenosine 3',5'-bisphosphate(in) + ADP(out) = adenosine 3',5'-bisphosphate(out) + ADP(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72847", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72847" } ] }, { "id": "72851", "name": "", "equation": "AMP(in) + ADP(out) = AMP(out) + ADP(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72851", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72851" } ] }, { "id": "73087", "name": "", "equation": "FAD(in) + AMP(out) = FAD(out) + AMP(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73087", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73087" } ] }, { "id": "73091", "name": "", "equation": "FMN(in) + AMP(out) = FMN(out) + AMP(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73091", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73091" } ] }, { "id": "73095", "name": "", "equation": "AMP(out) + CoA(in) = AMP(in) + CoA(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73095", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73095" } ] }, { "id": "73099", "name": "", "equation": "3'-dephospho-CoA(in) + AMP(out) = 3'-dephospho-CoA(out) + AMP(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73099", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73099" } ] }, { "id": "73143", "name": "", "equation": "FAD(in) + CoA(out) = FAD(out) + CoA(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73143" } ] }, { "id": "73147", "name": "", "equation": "FAD(in) + adenosine 3',5'-bisphosphate(out) = FAD(out) + adenosine 3',5'-bisphosphate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73147", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73147" } ] }, { "id": "73151", "name": "", "equation": "FMN(in) + CoA(out) = FMN(out) + CoA(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73151", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73151" } ] }, { "id": "73155", "name": "", "equation": "FMN(in) + adenosine 3',5'-bisphosphate(out) = FMN(out) + adenosine 3',5'-bisphosphate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73155", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73155" } ] }, { "id": "73159", "name": "", "equation": "FMN(out) + NAD(+)(in) = FMN(in) + NAD(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73159", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73159" } ] }, { "id": "73163", "name": "", "equation": "FAD(out) + NAD(+)(in) = FAD(in) + NAD(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73163", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73163" } ] }, { "id": "73167", "name": "", "equation": "NAD(+)(in) + CoA(out) = NAD(+)(out) + CoA(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73167", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73167" } ] }, { "id": "73171", "name": "", "equation": "adenosine 3',5'-bisphosphate(out) + NAD(+)(in) = adenosine 3',5'-bisphosphate(in) + NAD(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73171", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73171" } ] }, { "id": "73175", "name": "", "equation": "FMN(out) + ADP(in) = FMN(in) + ADP(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73175", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73175" } ] }, { "id": "73183", "name": "", "equation": "FAD(out) + ADP(in) = FAD(in) + ADP(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73183", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73183" } ] }, { "id": "73447", "name": "", "equation": "acetyl-CoA(in) + AMP(out) = acetyl-CoA(out) + AMP(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73447", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73447" } ] }, { "id": "73451", "name": "", "equation": "adenosine 3',5'-bisphosphate(in) + AMP(out) = adenosine 3',5'-bisphosphate(out) + AMP(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73451", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73451" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1G7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 307, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1G7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1G7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 241, "end_pos": 243 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B176-1", "uniprot_ac": "A0A287B176", "uniprot_id": "A0A287B176_PIG", "mass": { "chemical_mass": 34564.0, "monoisotopic_mass": 34564.0 }, "refseq": {}, "gene_names": [ { "name": "GULP1", "type": "recommended", "evidence": [ { "id": "A0A287B176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B176" } ] } ], "protein_names": [ { "name": "PTB domain-containing engulfment adapter protein 1", "type": "recommended", "evidence": [ { "id": "A0A287B176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B176/entry#names_and_taxonomy" } ] }, { "name": "Cell death protein 6 homolog", "type": "synonym", "evidence": [ { "id": "A0A287B176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B176/entry#names_and_taxonomy" } ] }, { "name": "PTB domain adapter protein CED-6", "type": "synonym", "evidence": [ { "id": "A0A287B176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B176/entry#names_and_taxonomy" } ] }, { "name": "Protein GULP", "type": "synonym", "evidence": [ { "id": "A0A287B176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B176/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B176", "url": "https://www.uniprot.org/uniprotkb/A0A287B176" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GULP1", "url": "https://www.uniprot.org/uniprotkb/A0A287B176", "locus": { "chromosome": "15", "start_pos": 93252180, "end_pos": 92911054, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016033", "url": "https://www.ensembl.org/id/ENSSSCG00000016033" } ] } } ], "crossref": [ { "id": "A0A287B176", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B176", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016033", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016033", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14686", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14686", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100621868", "url": "https://www.ncbi.nlm.nih.gov/gene/100621868", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232:SF78", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232:SF78", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287A6Y8", "url": "https://www.uniprot.org/uniprotkb/A0A287A6Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A6Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A6Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AV30", "url": "https://www.uniprot.org/uniprotkb/A0A287AV30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AV30-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AV30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXG9", "url": "https://www.uniprot.org/uniprotkb/A0A287AXG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B176", "url": "https://www.uniprot.org/uniprotkb/A0A287B176", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B176-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B176-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAP2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYI9", "url": "https://www.uniprot.org/uniprotkb/F1RYI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYI9-1", "url": "https://www.uniprot.org/uniprotkb/F1RYI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITQVSASPAGSVTPKSPSTDIFDMIPFSALSHQSSIPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAGDFPPDIQSKLDEMQRQRWLVYCFHNFKQLILKAKP", "length": 302, "header": "tr|A0A287B176-1|A0A287B176_PIG Isoform 1 of PTB domain-containing engulfment adapter protein 1 OS=Sus scrofa OX=9823 GN=GULP1 PE=3 SV=2 CANONICAL=A0A287B176-1" }, "isoforms": [ { "isoform_ac": "A0A287A6Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B176/entry#A0A287A6Y8-1", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITQVSASPAGSVTPKSPSTDIFDMIPFSALSHQSSIPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAGDFPPDIQSKLDEMQRQRWRGSKWD", "length": 291, "header": "tr|A0A287A6Y8-1|A0A287B176_PIG Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Sus scrofa OX=9823 GN=GULP1 PE=3 SV=3 CANONICAL=A0A287B176-1" }, "locus": { "chromosome": "15", "start_pos": 93250234, "end_pos": 93154712, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060805.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060805.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039532.3", "url": "https://www.ensembl.org/id/ENSSSCP00000039532.3" } ] } }, { "isoform_ac": "A0A287AV30-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B176/entry#A0A287AV30-1", "sequence": { "sequence": "MQSFSRSHCLIGSCSSDEVSSNLFLRNCQNRKEQFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITQVSASPLLHKMSDHEQHGFQRCSPSFWHNTDGSSPCLNISSITVTPVNSPDSRLSLGLLIPSPSKCGLPKPVSESSIPRPHAGSVTPKSPSTDIFDMIPFSALSHQSSIPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 383, "header": "tr|A0A287AV30-1|A0A287B176_PIG Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Sus scrofa OX=9823 GN=GULP1 PE=3 SV=3 CANONICAL=A0A287B176-1" }, "locus": { "chromosome": "15", "start_pos": 93250284, "end_pos": 93159107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060588.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060588.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047793.3", "url": "https://www.ensembl.org/id/ENSSSCP00000047793.3" } ] } }, { "isoform_ac": "A0A287AXG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B176/entry#A0A287AXG9-1", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITQVSASPLLHKMSDHEQHGFQRCSPSFWHNTDGSSPCLNISSITVTPVNSPDSRLSLGLLIPSPSKCGLPKPVSESSIPRPHAGSVTPKSPSTDIFDMIPFSALSHQSSIPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 379, "header": "tr|A0A287AXG9-1|A0A287B176_PIG Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Sus scrofa OX=9823 GN=GULP1 PE=3 SV=2 CANONICAL=A0A287B176-1" }, "locus": { "chromosome": "15", "start_pos": 93250284, "end_pos": 93154712, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039708.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039708.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048847.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048847.2" } ] } }, { "isoform_ac": "A0A287B176-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B176/entry#A0A287B176-1", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITQVSASPAGSVTPKSPSTDIFDMIPFSALSHQSSIPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAGDFPPDIQSKLDEMQRQRWLVYCFHNFKQLILKAKP", "length": 302, "header": "tr|A0A287B176-1|A0A287B176_PIG Isoform 1 of PTB domain-containing engulfment adapter protein 1 OS=Sus scrofa OX=9823 GN=GULP1 PE=3 SV=2 CANONICAL=A0A287B176-1" }, "locus": { "chromosome": "15", "start_pos": 93246060, "end_pos": 93154712, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047791.2", "url": "https://www.ensembl.org/id/ENSSSCT00000047791.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049977.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049977.2" } ] } }, { "isoform_ac": "A0A8W4FAP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B176/entry#A0A8W4FAP2-1", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCVSMPDVLGWLVLFYKPGIVLFPVLVKYLEVNKVCKYLTTLIDSSCHENMF", "length": 183, "header": "tr|A0A8W4FAP2-1|A0A287B176_PIG Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Sus scrofa OX=9823 GN=GULP1 PE=3 SV=1 CANONICAL=A0A287B176-1" }, "locus": { "chromosome": "15", "start_pos": 93210367, "end_pos": 93154712, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106577.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106577.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076337.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076337.1" } ] } }, { "isoform_ac": "F1RYI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B176/entry#F1RYI9-1", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRNLVFSCDFASLPDASHGDQSSRSSRCWIQDLETENMELKNKVQDLENQLRITQVSASPAGSVTPKSPSTDIFDMIPFSALSHQSSIPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 331, "header": "tr|F1RYI9-1|A0A287B176_PIG Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Sus scrofa OX=9823 GN=GULP1 PE=3 SV=3 CANONICAL=A0A287B176-1" }, "locus": { "chromosome": "15", "start_pos": 93250284, "end_pos": 93154712, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017458.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017458.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016988.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016988.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FAP2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAP2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A287B176", "url": "https://www.uniprot.org/uniprotkb/A0A287B176" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A287B176", "url": "https://www.uniprot.org/uniprotkb/A0A287B176" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B176-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 302, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B176-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B176" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B176" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 155, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 235, "end_pos": 237 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1X2-1", "uniprot_ac": "A0A287B1X2", "uniprot_id": "A0A287B1X2_PIG", "mass": { "chemical_mass": 43584.0, "monoisotopic_mass": 43584.0 }, "refseq": { "ac": "XP_020955204", "name": "serpin B3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955204" }, "gene_names": [ { "name": "LOC110261636", "type": "recommended", "evidence": [ { "id": "A0A287B1X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2" } ] }, { "name": "LOC110261636", "type": "synonym", "evidence": [ { "id": "XP_020955204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955204" } ] } ], "protein_names": [ { "name": "Serpin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A287B1X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2/entry#names_and_taxonomy" } ] }, { "name": "serpin B3-like", "type": "synonym", "evidence": [ { "id": "XP_020955204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955204" } ] } ], "function": [ { "annotation": "Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIM0#function" }, { "database": "UniProtKB", "id": "ARBA00057920", "url": "https://www.uniprot.org/uniprotkb/ARBA00057920#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1X2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110261636", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2", "locus": {} } ], "crossref": [ { "id": "A0A287B1X2", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1X2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000033560", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033560", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19956", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19956", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110261636", "url": "https://www.ncbi.nlm.nih.gov/gene/110261636", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110261636", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261636", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B1X2", "url": "https://www.orthodb.org/?gene=A0A287B1X2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461:SF186", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461:SF186", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020955204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955204", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AAT5", "url": "https://www.uniprot.org/uniprotkb/A0A287AAT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AAT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AAT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1X2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBV0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDR4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIC1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FK30", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FK30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FK30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FK30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQB4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSLSESIIQFAVDLFQQIRRSEGGNIFYSPLSIMSALAMTYLGSRGHTASEIRKALHLKELAENAEGATADLVGRAGTVHRQFQRLLTELNKPTNAYELSVANRLYGDKEVSFSQDYLENVKKFYLASVASVDFVNAAEESRQMINSWVESQTKGKIKDLFPKGILSSSTTLVLVNAIYFKGRWLQEFKKENTSKEKFWLNKDTSKSVQMMRETRAFKFASLEHLHVKILEIPYTGQELSMLLLLPDEVDGLRKLEEGLTAEKLLAWTSSQNMKESQVDLHLPRFKVEENYKLMAKLEALGMVSAFRADADFSGMTGRRELAISSVVHKSFVEVTEEGTEAAAATGVVTGMTSAPLNNHFHCDHPFLFFIRHNKTNSILFCGRVSSP", "length": 388, "header": "tr|A0A287B1X2-1|A0A287B1X2_PIG Isoform 1 of Serpin domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110261636 PE=3 SV=1 CANONICAL=A0A287B1X2-1" }, "isoforms": [ { "isoform_ac": "A0A287AAT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2/entry#A0A287AAT5-1", "sequence": { "sequence": "MSSLSESIIQFAVDLFQQIRRSEGGNIFYSPLSIMSALAMTYLGSRGHTASEIRKALHLKELAENAEGATADLVGRAGTVHRQFQRLLTELNKPTNAYELSVANRLYGDKEVSFSQDYLENVKKFYLASVASVDFVNAAEESRQMINSWVESQTKGKIKDLFPKGILSSSTTLVLVNAIYFKGRWLQEFKKENTSKEKFWLNKLEEGLTAEKLLAWTSSQNMKESQVDLHLPRFKVEENYKLMAKLEALGMVSAFRADADFSGMTGRRELAISSVVHKSFVEVTEEGTEAAAATGVVTGMTSAPLNNHFHCDHPFLFFIRHNKTNSILFCGRVSSP", "length": 336, "header": "tr|A0A287AAT5-1|A0A287B1X2_PIG Computationally mapped isoform of Serpin domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110261636 PE=3 SV=3 CANONICAL=A0A287B1X2-1" }, "locus": { "chromosome": "1", "start_pos": 158078831, "end_pos": 158074168, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043367.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043367.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041003.3", "url": "https://www.ensembl.org/id/ENSSSCP00000041003.3" } ] } }, { "isoform_ac": "A0A287B1X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2/entry#A0A287B1X2-1", "sequence": { "sequence": "MSSLSESIIQFAVDLFQQIRRSEGGNIFYSPLSIMSALAMTYLGSRGHTASEIRKALHLKELAENAEGATADLVGRAGTVHRQFQRLLTELNKPTNAYELSVANRLYGDKEVSFSQDYLENVKKFYLASVASVDFVNAAEESRQMINSWVESQTKGKIKDLFPKGILSSSTTLVLVNAIYFKGRWLQEFKKENTSKEKFWLNKDTSKSVQMMRETRAFKFASLEHLHVKILEIPYTGQELSMLLLLPDEVDGLRKLEEGLTAEKLLAWTSSQNMKESQVDLHLPRFKVEENYKLMAKLEALGMVSAFRADADFSGMTGRRELAISSVVHKSFVEVTEEGTEAAAATGVVTGMTSAPLNNHFHCDHPFLFFIRHNKTNSILFCGRVSSP", "length": 388, "header": "tr|A0A287B1X2-1|A0A287B1X2_PIG Isoform 1 of Serpin domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110261636 PE=3 SV=1 CANONICAL=A0A287B1X2-1" }, "locus": { "chromosome": "1", "start_pos": 158078831, "end_pos": 158074168, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082772.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082772.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073432.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073432.1" } ] } }, { "isoform_ac": "A0A8W4FAJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2/entry#A0A8W4FAJ7-1", "sequence": { "sequence": "MSSLSESIIQFAVDLFQQIRRSEGGNIFYSPLSIMSALAMTYLGSRGHTASEIRKVGGTSEGQRLASDSPEVGRAGTVHRQFQRLLTELNKPTNAYELSVANRLYGDKEVSFSQDYLENVKKFYLASVASVDFVNAAEESRQMINSWVESQTKGKIKDLFPKGILSSSTTLVLVNAIYFKGRWLQEFKKENTSKEKFWLNKVLSISYVQAFKFASLEHLHVKILEIPYTGQELSMLLLLPDEVDGLRKLEEGLTAEKLLAWTSSQNMKESQVDLHLPRFKVEENYKLMAKADADFSGMTGRRELAISSVVHKSFVEVTEEGTEAAAATGVVTGMTSAPLNNHFHCDHPFLFFIRHNKTNSILFCGRVSSP", "length": 370, "header": "tr|A0A8W4FAJ7-1|A0A287B1X2_PIG Computationally mapped isoform of Serpin domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110261636 PE=3 SV=1 CANONICAL=A0A287B1X2-1" }, "locus": { "chromosome": "1", "start_pos": 158078831, "end_pos": 158074168, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106725.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106725.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076421.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076421.1" } ] } }, { "isoform_ac": "A0A8W4FBV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2/entry#A0A8W4FBV0-1", "sequence": { "sequence": "MSSLSESIIQFAVDLFQQIRRSEGGNIFYSPLSIMSALAMTYLGSRGHTASEIRKALHLKELAENAEGATVGRAGTVHRQFQRLLTELNKPTNAYELSVANRLYGDKEVSFSQDYLENVKKFYLASVASVDFVNAAEESRQMINSWVESQTKGKIKDLFPKGILSSSTTLVLVNAIYFKGRWLQEFKKENTSKEKFWLNKVLSINDERNQSFQICQELSMLLLLPDEVDGLRKLEEGLTAEKLLAWTSSQNMKESQVDLHLPRFKVEENYKLMAKADADFSGMTGRRELAISSVVHKSFVEVTEEGTEAAAATGVVTGMTSAPLNNHFHCDHPFLFFIRHNKTNSILFCGRVSSP", "length": 355, "header": "tr|A0A8W4FBV0-1|A0A287B1X2_PIG Computationally mapped isoform of Serpin domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110261636 PE=3 SV=1 CANONICAL=A0A287B1X2-1" }, "locus": { "chromosome": "1", "start_pos": 158078831, "end_pos": 158074168, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102656.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102656.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076800.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076800.1" } ] } }, { "isoform_ac": "A0A8W4FDR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2/entry#A0A8W4FDR4-1", "sequence": { "sequence": "MSSLSESIIQFAVDLFQQIRRSEGGNIFYSPLSIMSALAMTYLGSRGHTASEIRKVGGSFLSFEHLALLSLLVGRAGTVHRQFQRLLTELNKPTNAYELSVANRLYGDKEVSFSQDYLENVKKFYLASVASVDFVNAAEESRQMINSWVESQTKGKIKDLFPKGILSSSTTLVLVNAIYFKGRWLQEFKKENTSKEKFWLNKVLSISYHLHVKILEIPYTGQELSMLLLLPDEVDGLRKLEEGLTAEKLLAWTSSQNMKESQVDLHLPRFKVEENYKLMAKADADFSGMTGRRELAISSVVHKSFVEVTEEGTEAAAATGVVTGMTSAPLNNHFHCDHPFLFFIRHNKTNSILFCGRVSSP", "length": 361, "header": "tr|A0A8W4FDR4-1|A0A287B1X2_PIG Computationally mapped isoform of Serpin domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110261636 PE=3 SV=1 CANONICAL=A0A287B1X2-1" }, "locus": { "chromosome": "1", "start_pos": 158078831, "end_pos": 158074168, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097082.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097082.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076999.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076999.1" } ] } }, { "isoform_ac": "A0A8W4FIC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2/entry#A0A8W4FIC1-1", "sequence": { "sequence": "MLPWEHGRWGWSVVCTHRAFEKKFAVDLFQQIRRSEGGNIFYSPLSIMSALAMTYLGSRGHTASEIRKVEQEERITGKSERKDVGRAGTVHRQFQRLLTELNKPTNAYELSVANRLYGDKEVSFSQDYLENVKKFYLASVASVDFVNAAEESRQMINSWVESQTKGKIKDLFPKGILSSSTTLVLVNAIYFKGRWLQEFKKENTSKEKFWLNKVLSISYHLHVKILEIPYTGQELSMLLLLPDEVDGLRKLEEGLTAEKLLAWTSSQNMKESQVDLHLPRFKVEENYKLMAKADADFSGMTGRRELAISSVVHKSFVEVTEEGTEAAAATGVVTGMTSAPLNNHFHCDHPFLFFIRHNKTNSILFCGRVSSP", "length": 372, "header": "tr|A0A8W4FIC1-1|A0A287B1X2_PIG Computationally mapped isoform of Serpin domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110261636 PE=3 SV=1 CANONICAL=A0A287B1X2-1" }, "locus": { "chromosome": "1", "start_pos": 158078831, "end_pos": 158073717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095770.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095770.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079193.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079193.1" } ] } }, { "isoform_ac": "A0A8W4FIM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2/entry#A0A8W4FIM0-1", "sequence": { "sequence": "MSSLSESIIQFAVDLFQQIRRSEGGNIFYSPLSIMSALAMTYLGSRGHTASEIRKLLHFHGNGMKGFEMAGTVHRQFQRLLTELNKPTNAYELSVANRLYGDKEVSFSQDYLENVKKFYLASVASVDFVNAAEESRQMINSWVESQTKGKIKDLFPKGILSSSTTLVLVNAIYFKGRWLQEFKKENTSKEKFWLNKVLSISYVQAFKFASLEHLHVKILEIPYTGQELSMLLLLPDEVDGLRKLEEGLTAEKLLAWTSSQNMKESQVDLHLPRFKVEENYKLMAKADADFSGMTGRRELAISSVVHKSFVEVTEEGTEAAAATGVVTGMTSAPLNNHFHCDHPFLFFIRHNKTNSILFCGRVSSP", "length": 365, "header": "tr|A0A8W4FIM0-1|A0A287B1X2_PIG Computationally mapped isoform of Serpin domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110261636 PE=3 SV=1 CANONICAL=A0A287B1X2-1" }, "locus": { "chromosome": "1", "start_pos": 158078831, "end_pos": 158074168, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106309.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106309.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079294.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079294.1" } ] } }, { "isoform_ac": "A0A8W4FK30-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2/entry#A0A8W4FK30-1", "sequence": { "sequence": "EVVFPHGDLMLTKFAVDLFQQIRRSEGGNIFYSPLSIMSALAMTYLGSRGHTASEIRKVEQEERITGKSERKDVGRAGTVHRQFQRLLTELNKPTNAYELSVANRLYGDKEVSFSQDYLENVKKFYLASVASVDFVNAAEESRQMINSWVESQTKGKIKDLFPKGILSSSTTLVLVNAIYFKGRWLQEFKKENTSKEKFWLNKVLSISYVQAFKFASLEHLHVKILEIPYTGQELSMLLLLPDEVDGLRKLEEGLTAEKLLAWTSSQNMKESQVDLHLPRFKVEENYKLMAKADADFSGMTGRRELAISSVVHKSFVEVTEEGTEAAAATGVVTGMTSAPLNNHFHCDHPFLFFIRHNKTNSILFCGRVSSP", "length": 372, "header": "tr|A0A8W4FK30-1|A0A287B1X2_PIG Computationally mapped isoform of Serpin domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110261636 PE=3 SV=1 CANONICAL=A0A287B1X2-1" }, "locus": { "chromosome": "1", "start_pos": 158078831, "end_pos": 158073323, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096990.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096990.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079255.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079255.1" } ] } }, { "isoform_ac": "A0A8W4FQB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2/entry#A0A8W4FQB4-1", "sequence": { "sequence": "MSSLSESIIQFAVDLFQQIRRSEGGNIFYSPLSIMSALAMTYLGSRGHTASEIRKVGGSFLSFEHLALLSLLVCFREHASTCKTGKPAGTVHRQFQRLLTELNKPTNAYELSVANRLYGDKEVSFSQDYLENVKKFYLASVASVDFVNAAEESRQMINSWVESQTKGKIKDLFPKGILSSSTTLVLVNAIYFKGRWLQEFKKENTSKEKFWLNKVLSISYHLHVKILEIPYTGQELSMLLLLPDEVDGLRKGLTAEKLLAWTSSQNMKESQVDLHLPRFKVEENYKLMAKADADFSGMTGRRELAISSVVHKSFVEVTEEGTEAAAATGVVTGMTSAPLNNHFHCDHPFLFFIRHNKTNSILFCGRVSSP", "length": 370, "header": "tr|A0A8W4FQB4-1|A0A287B1X2_PIG Computationally mapped isoform of Serpin domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110261636 PE=3 SV=1 CANONICAL=A0A287B1X2-1" }, "locus": { "chromosome": "1", "start_pos": 158078831, "end_pos": 158074168, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099129.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099129.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081189.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081189.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FAJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAJ7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110261636", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261636", "resource": "KEGG Pathway" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1X2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2" } ], "pmid": "" }, { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1X2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1X2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1X2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1X2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1X2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 388, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1X2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1X2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B1X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X2" }, { "id": "SM00093", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serpin", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 388, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 374, "end_pos": 376 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1Y6-1", "uniprot_ac": "A0A287B1Y6", "uniprot_id": "A0A287B1Y6_PIG", "mass": { "chemical_mass": 42800.0, "monoisotopic_mass": 42800.0 }, "refseq": {}, "gene_names": [ { "name": "TM6SF2", "type": "recommended", "evidence": [ { "id": "A0A287B1Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6" } ] } ], "protein_names": [ { "name": "Transmembrane 6 superfamily member 2", "type": "synonym", "evidence": [ { "id": "A0A287B1Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TM6SF2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6", "locus": { "chromosome": "2", "start_pos": 58626805, "end_pos": 58617205, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000059192", "url": "https://www.ensembl.org/id/ENSSSCG00000059192" } ] } } ], "crossref": [ { "id": "ENSSSCG00000034887", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034887", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21106", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21106", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR033118", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033118", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110259311", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259311", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQMLMYM", "url": "https://omabrowser.org/oma/group/VQMLMYM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287ACW9", "url": "https://www.orthodb.org/?gene=A0A287ACW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14568", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14568", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14568:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14568:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287ACW9", "url": "https://www.uniprot.org/uniprotkb/A0A287ACW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ACW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ACW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1Y6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVPPLAGKIAVLSLGALPLSYALNHLSALSYSLGVVLMSALILGLLFLAIYSLSRSDIYYDPLYAVFAVFAFTSVVDLLIALQEDGYVGGFMEFYTKEGESYLRTAHGLFICYWDGIVHYLLYLAMAGAIRKRKRYRNFGLYWLGSFVMSLLVFLPGNILGKYSSEIRPTFFLTIPYVLVPCWAGFRVFNQTQASTCCTPNMVQEEQRKSLLWRPIDLALIIYLTFAAFFTLFRGLVVLDCPMDACFVYIYQYEPYLRDPVAYPKVQMLVNMFYVLPFYGLAIYGLIFPGCSWLPDWTLVFAGAIGQAQFSHMGASMHLRTPFTYRVPEDNWACFFTCNLLYALGPHLLAFRCLWRPAFFLHPPPGPPAHHEKQH", "length": 376, "header": "tr|A0A287B1Y6-1|A0A287B1Y6_PIG Isoform 1 of Transmembrane 6 superfamily member 2 OS=Sus scrofa OX=9823 GN=TM6SF2 PE=3 SV=1 CANONICAL=A0A287B1Y6-1" }, "isoforms": [ { "isoform_ac": "A0A287ACW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6/entry#A0A287ACW9-1", "sequence": { "sequence": "MDVPPLAGKIAVLSLGALPLSYALNHLSALSYSLGVVLMSALILGLLFLAIYSLSRSDIYYDPLYAVFAVFAFTSVVDLLIALQEDGYVGGFMEFYTKEGESYLRTAHGLFICYWDGIVHYLLYLAMAGAIRKRKRYRNFGLYWLGSFVMSLLVFLPGNILGKYSSEIRPTFFLTIPYVLVPCWAGFRVFNQTQASTCCTPNMVQEEQRKSLLWRPIDLALIIYLTFAAFFTLFRGLVVLDCPMDACFVYIYQYEPYLRDPVAYPKVQMLVNMFYVLPFYGLAIYGLIFPGCSWLPDWTLVFAGAIGQGDARSLTDSSPSSRFPNVEKKELDTYTPNLKRHSSHTWVPPCIYARPSPTVCLRITGPASSRATYCMRWAPTCWPSAACGALPSSYTRLLAPQPTTRSSTEGAKRLPKTLFTCPASPAPRRLFWDF", "length": 434, "header": "tr|A0A287ACW9-1|A0A287B1Y6_PIG Computationally mapped isoform of Transmembrane 6 superfamily member 2 OS=Sus scrofa OX=9823 GN=TM6SF2 PE=3 SV=1 CANONICAL=A0A287B1Y6-1" }, "locus": { "chromosome": "2", "start_pos": 58626341, "end_pos": 58617350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052426.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052426.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041822.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041822.1" } ] } }, { "isoform_ac": "A0A287B1Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6/entry#A0A287B1Y6-1", "sequence": { "sequence": "MDVPPLAGKIAVLSLGALPLSYALNHLSALSYSLGVVLMSALILGLLFLAIYSLSRSDIYYDPLYAVFAVFAFTSVVDLLIALQEDGYVGGFMEFYTKEGESYLRTAHGLFICYWDGIVHYLLYLAMAGAIRKRKRYRNFGLYWLGSFVMSLLVFLPGNILGKYSSEIRPTFFLTIPYVLVPCWAGFRVFNQTQASTCCTPNMVQEEQRKSLLWRPIDLALIIYLTFAAFFTLFRGLVVLDCPMDACFVYIYQYEPYLRDPVAYPKVQMLVNMFYVLPFYGLAIYGLIFPGCSWLPDWTLVFAGAIGQAQFSHMGASMHLRTPFTYRVPEDNWACFFTCNLLYALGPHLLAFRCLWRPAFFLHPPPGPPAHHEKQH", "length": 376, "header": "tr|A0A287B1Y6-1|A0A287B1Y6_PIG Isoform 1 of Transmembrane 6 superfamily member 2 OS=Sus scrofa OX=9823 GN=TM6SF2 PE=3 SV=1 CANONICAL=A0A287B1Y6-1" }, "locus": { "chromosome": "2", "start_pos": 58626262, "end_pos": 58617350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048114.2", "url": "https://www.ensembl.org/id/ENSSSCT00000048114.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050446.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050446.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ACW9", "url": "https://www.uniprot.org/uniprotkb/A0A287ACW9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110259311", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259311", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IE26-1", "protein_name": "Transmembrane 6 superfamily member 2", "gene_name": "Tm6sf2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDIPPLASKTTAMSLGALPVSYALNHVSVLSQPLCVVLMSALILGLLFMAIYSLSHGEITYDPLYAVFVIFSFTSVVDLIIALQEDGYVMGFMDFYTKEGEPYLRTAHGIFICYWDGTVHYLLYLAMAGAIRKRKRYRNLGLYWLGSFAMSLLVFLPGNILGKYSSEIRPAFFLTILYMLVPCWAGVRIFSQSRTPTSYTPDMVQEEQKKGLLQRPADLTLIIYLILAAFFALFRGLVVLDCPTDACFIYIYQYEPYLRDPVAYPKLQMLMYLFYALPFYCLAAYALTFPGCSWLPDWALVFAGAIGQAQFSHMGASMHLRTPFTYRVPEDTWTTFFLSNMLFALGPHLLAFRCLWRPAFFLQAPPWASEGPGKKQQ", "length": 377 }, "evidence": [ { "id": "A0A287B1Y6", "url": "https://omabrowser.org/oma/group/A0A287B1Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B0BNG2-1", "protein_name": "Transmembrane 6 superfamily member 2", "gene_name": "Tm6sf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDIPPLAGRTVAMSLGALPVSYVLNQVSAFSQPLCVVLTSALVLGLLFMAVYSLSHGEITYDPLYAVFVVFSFTSVVDLVIALQEDGYLMGLMDFYAKEGEPYLRTAHGIFICYWDGTVHYLLYLTMAGAIRKRKRYRNLGLYWLGSFAMSLLVFLPGNILGKYSSEIRPTFFLAILYMLVPCWAGMRIFNQSPAPSSCTCDVVQEEQKKSLLQRPADLTLIVYLILAAFFTVFRGLVVLDCPADACFIYIYQYEPYLRDPVAYPKLQMLMYLFYALPFYCLAAYALTFPGCSWLPDWALVFAGAIGQAQFSHMGASMHLRTPFTYRVPEDTWATFLLSNLLFALGPHLLALRCLWRPAFFLRAAPPSSPQDQGKKQQ", "length": 378 }, "evidence": [ { "id": "A0A287B1Y6", "url": "https://omabrowser.org/oma/group/A0A287B1Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R1J1-1", "protein_name": "Transmembrane 6 superfamily member 2", "gene_name": "Tm6sf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDIPPLAGRTVAMSFCALPVSYLLNQVSAFSQPLFVVLTSALILGLLFLAVYSLSHGEITYDPLYAVFVIFSFTSVVDLVIALQEDGYMMGFMDFYTKEGEPYLRTAHGIFICYWDGTVHYLLYLTMAGAIRKRKRYRNLGLYWLGSFAMSILVFLPGNILGKYSSEMRPTFFLAILYMLVPCWAGVRIFNQSRAPTSYTPDMVQEEQKKSLLQRPADLALIVYLIFAALFTVFRGLVVLDCPTDACFIYIYQYEPYLRDPVAYPKLQMLMYLFYALPFYCLAAYALAFPGCSWLPDWALVFAGAIGQAQFSHMGASMHMRTPFTYRVPEDTWATFFLSNLLLALGPHLLAFRCLWRPAFFLHAALPSSPQDQDKKQQ", "length": 378 }, "evidence": [ { "id": "A0A287B1Y6", "url": "https://omabrowser.org/oma/group/A0A287B1Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZW4-1", "protein_name": "Transmembrane 6 superfamily member 2", "gene_name": "TM6SF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDIPPLAGKIAALSLSALPVSYALNHVSALSHPLWVALMSALILGLLFVAVYSLSHGEVSYDPLYAVFAVFAFTSVVDLIIALQEDSYVVGFMEFYTKEGEPYLRTAHGVFICYWDGTVHYLLYLAMAGAICRRKRYRNFGLYWLGSFAMSILVFLTGNILGKYSSEIRPAFFLTIPYLLVPCWAGMKVFSQPRALTRCTANMVQEEQRKGLLQRPADLALVIYLILAGFFTLFRGLVVLDCPTDACFVYIYQYEPYLRDPVAYPKVQMLMYMFYVLPFCGLAAYALTFPGCSWLPDWALVFAGGIGQAQFSHMGASMHLRTPFTYRVPEDTWGCFFVCNLLYALGPHLLAYRCLQWPAFFHQPPPSDPLALHKKQH", "length": 377 }, "evidence": [ { "id": "A0A287B1Y6", "url": "https://omabrowser.org/oma/group/A0A287B1Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6" } ], "pmid": "" }, { "name": "regulation of lipid metabolic process", "id": "GO:0019216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019216", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B1Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y6" }, { "id": "PS51751", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51751" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EXPERA", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 186, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B2G1-1", "uniprot_ac": "A0A287B2G1", "uniprot_id": "A0A287B2G1_PIG", "mass": { "chemical_mass": 220218.0, "monoisotopic_mass": 220218.0 }, "refseq": {}, "gene_names": [ { "name": "TANC2", "type": "recommended", "evidence": [ { "id": "A0A287B2G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2", "type": "synonym", "evidence": [ { "id": "A0A287B2G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B2G1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TANC2", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1", "locus": { "chromosome": "12", "start_pos": 15453241, "end_pos": 15813469, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017298", "url": "https://www.ensembl.org/id/ENSSSCG00000017298" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017298", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017298", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100515233", "url": "https://www.ncbi.nlm.nih.gov/gene/100515233", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25521", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25521", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AE32", "url": "https://www.uniprot.org/uniprotkb/A0A287AE32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AE32-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AE32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2G1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFRNSLKMLLTGGKSSRKNRSSDGGNEEPPERRQSSVDSRQSRSGQGGISTESDCAFEPDYAVPPLPVSEGDAEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGDQYNMEVQDENQTSAITQRISPCSTLTSSTASPPASSPCSTLPPVSTSAAAKDCSYGAVTSPTSTLESRDSGIIATLTSYSENMERSKYVGESSKELGSGGNVKPWQSQKSSMDSCLYRVDENMTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSMAGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNANVNQGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQPPSAHSSITSGSCPGTPEMRRRQEEAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQLAAYREQLLREPHLQSMLSLRSCVQDPMASFRRGVLEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLIVTVRTSLQEITKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGSIEGTLEWEDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGCQTLPSRPRGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQMQQQPPQQPQQQLPEETEPEPQHEDIYSVQDIFEEEYLEQDVENVSIGLQTEARPSQGLPIIQSPPSSPAHRDSAYISSSPLGSHQVFDFRSSSSVGSPTRQSFQSTSPALSPTHQNSHYRPSPPHTSPAHQGGSYRFSPPPVGGQGKEYPSPPPSPLRRGPQYRASPPAESMSVYRSQSGSPVRYQQEASVGQLPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVISTGAYGQVAHSMASKYQSSQGDIGVSQSRLVYQGSIGGIVGDGRPVQHVQASLSAGAICQHGGLAKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPVCHSKLDLERSSSQLGSPDVSHLIRRPISVNPSEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSAANLTPTFRPSSSIQQMEIPLKPAYDRSCDELSPVSPTQGGYPSEPTRSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVLSPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEDEYYSPHGMLANGSRGDLLERVSQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "length": 1996, "header": "tr|A0A287B2G1-1|A0A287B2G1_PIG Isoform 1 of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 OS=Sus scrofa OX=9823 GN=TANC2 PE=3 SV=2 CANONICAL=A0A287B2G1-1" }, "isoforms": [ { "isoform_ac": "A0A287AE32-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1/entry#A0A287AE32-1", "sequence": { "sequence": "MFRNSLKMLLTGGKSSRKNRSSDGGNEEPPERRQSSVDSRQSRSGQGGISTESDCAFEPDYAVPPLPVSEGDAEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGDQYNMEVQDENQTSAITQRISPCSTLTSSTASPPASSPCSTLPPVSTSAAAKDCSYGAVTSPTSTLESRDSGIIATLTSYSENMERSKYVGESSKELGSGGNVKPWQSQKSSMDSCLYRVDENMTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSMAGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNANVNQGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQPPSAHSSITSGSCPGTPEMRRRQEEAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQLAAYREQLLREPHLQSMLSLRSCVQDPMASFRRGVLEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLIVTVRTSLQEITKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGSIEGTLEWEDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQMQQQPPQQPQQQLPEETEPEPQHEDIYSVQDIFEEEYLEQDVENVSIGLQTEARPSQGLPIIQSPPSSPAHRDSAYISSSPLGSHQVFDFRSSSSVGSPTRQSFQSTSPALSPTHQNSHYRPSPPHTSPAHQGGSYRFSPPPVGGQGKEYPSPPPSPLRRGPQYRASPPAESMSVYRSQSGSPVRYQQEASVGQLPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVISTGAYGQVAHSMASKYQSSQGDIGVSQSRLVYQGSIGGIVGDGRPVQHVQASLSAGAICQHGGLAKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPVCHSKLDLERSSSQLGSPDVSHLIRRPISVNPSEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSAANLTPTFRPSSSIQQMEIPLKPAYDRSCDELSPVSPTQGGYPSEPTRSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVLSPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEDEYYSPHGMLANGSRGDLLERVSQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "length": 1986, "header": "tr|A0A287AE32-1|A0A287B2G1_PIG Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 OS=Sus scrofa OX=9823 GN=TANC2 PE=3 SV=2 CANONICAL=A0A287B2G1-1" }, "locus": { "chromosome": "12", "start_pos": 15761716, "end_pos": 15454245, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063389.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063389.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042147.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042147.2" } ] } }, { "isoform_ac": "A0A287B2G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1/entry#A0A287B2G1-1", "sequence": { "sequence": "MFRNSLKMLLTGGKSSRKNRSSDGGNEEPPERRQSSVDSRQSRSGQGGISTESDCAFEPDYAVPPLPVSEGDAEQELGPPPSVDEAANTLMTRLGFLLGEKVTEVQPGDQYNMEVQDENQTSAITQRISPCSTLTSSTASPPASSPCSTLPPVSTSAAAKDCSYGAVTSPTSTLESRDSGIIATLTSYSENMERSKYVGESSKELGSGGNVKPWQSQKSSMDSCLYRVDENMTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSMAGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNANVNQGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANRELPLTQPPSAHSSITSGSCPGTPEMRRRQEEAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQLAAYREQLLREPHLQSMLSLRSCVQDPMASFRRGVLEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLIVTVRTSLQEITKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGSIEGTLEWEDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIGCQTLPSRPRGPATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQMQQQPPQQPQQQLPEETEPEPQHEDIYSVQDIFEEEYLEQDVENVSIGLQTEARPSQGLPIIQSPPSSPAHRDSAYISSSPLGSHQVFDFRSSSSVGSPTRQSFQSTSPALSPTHQNSHYRPSPPHTSPAHQGGSYRFSPPPVGGQGKEYPSPPPSPLRRGPQYRASPPAESMSVYRSQSGSPVRYQQEASVGQLPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVISTGAYGQVAHSMASKYQSSQGDIGVSQSRLVYQGSIGGIVGDGRPVQHVQASLSAGAICQHGGLAKEDLPQRPSSAYRGGMRYSQTPQIGRSQSASYYPVCHSKLDLERSSSQLGSPDVSHLIRRPISVNPSEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSAANLTPTFRPSSSIQQMEIPLKPAYDRSCDELSPVSPTQGGYPSEPTRSRTTPFMGIIDKTARTQQYPHLHQQNRTWAVSSVDTVLSPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEDEYYSPHGMLANGSRGDLLERVSQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "length": 1996, "header": "tr|A0A287B2G1-1|A0A287B2G1_PIG Isoform 1 of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 OS=Sus scrofa OX=9823 GN=TANC2 PE=3 SV=2 CANONICAL=A0A287B2G1-1" }, "locus": { "chromosome": "12", "start_pos": 15761716, "end_pos": 15454245, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050601.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050601.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050433.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050433.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1835, "start_aa": "Thr", "end_pos": 1835, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1835", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AE32", "url": "https://www.uniprot.org/uniprotkb/A0A287AE32" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A287B2G1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A287B2G1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of dendritic spine morphogenesis", "id": "GO:0061001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061001", "evidence": [ { "database": "UniProtKB", "id": "A0A287B2G1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of postsynaptic density", "id": "GO:0098919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098919", "evidence": [ { "database": "UniProtKB", "id": "A0A287B2G1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1211, "end_pos": 1213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1306, "end_pos": 1308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1428, "end_pos": 1430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1800, "end_pos": 1802, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1871, "end_pos": 1873, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1910, "end_pos": 1912, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1934, "end_pos": 1936, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B2G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1" }, { "id": "PF25520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TANC1/2-like AAA+ ATPase lid", "eco_id": "ECO_0000259", "start_pos": 598, "end_pos": 692, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287B2G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G1" }, { "id": "PF25521", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25521" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TANC1/2-like winged helix", "eco_id": "ECO_0000259", "start_pos": 694, "end_pos": 846, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1835 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 1211, "end_pos": 1213 }, { "start_pos": 1306, "end_pos": 1308 }, { "start_pos": 1428, "end_pos": 1430 }, { "start_pos": 1800, "end_pos": 1802 }, { "start_pos": 1871, "end_pos": 1873 }, { "start_pos": 1910, "end_pos": 1912 }, { "start_pos": 1934, "end_pos": 1936 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 627, "end_pos": 629 }, { "start_pos": 636, "end_pos": 638 }, { "start_pos": 747, "end_pos": 749 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1Z4-1", "uniprot_ac": "A0A287B1Z4", "uniprot_id": "A0A287B1Z4_PIG", "mass": { "chemical_mass": 132515.0, "monoisotopic_mass": 132515.0 }, "refseq": {}, "gene_names": [ { "name": "NHSL2", "type": "recommended", "evidence": [ { "id": "A0A287B1Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z4" } ] } ], "protein_names": [ { "name": "NHS like 2", "type": "synonym", "evidence": [ { "id": "A0A287B1Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Z4", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NHSL2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z4", "locus": { "chromosome": "X", "start_pos": 58030951, "end_pos": 57742114, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012408", "url": "https://www.ensembl.org/id/ENSSSCG00000012408" } ] } } ], "crossref": [ { "id": "A0A287B1Z4", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1Z4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012408", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012408", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR024845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23039", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23039", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23039:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23039:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AMZ6", "url": "https://www.uniprot.org/uniprotkb/A0A287AMZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AMZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1Z4", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFYRRTVVPQRLCPRNPPQPLTELRDVSHLAALSLLRQLADLCGHSLALLEDLEGHLLALGRRTDSLFRRTVRLRRRLPCRLLGPEDDDEELAAANSGRENATATAHSRSSWRQPVNVFLSSGRPPSVEELLREAQLNLQSLLQEEYEEQYSEARLLGQTFRSADEAPEPTPSPRPQSARRLEFVLMPTKWQLNEDETTTQGVRAPEASLRPTTDKQAAWNSPFPLPVLEEKRWLQPCPMHSDIVPINVSGQQFDKHASLRQSLFNTETAVNPKSTLRRRRTIIGFSNYSQRDQGHSNSPAGSVACSSTSDIRPSHSVPEGVHGRVAVGQETRFPHLTSPVLRNPSSDPEELLQSRGGTKPPGMEGMGMVYSVPSSCNGPTGSTFSTSWKGDAFTYMTPSAAAQSSQVSENGKSPSSGNSWASLHTLPPLIPKEAATLFVTRDTPAGCSGSAGYSEHPTQRRQVSERPSKVSLLTGGTSKLETGPGGASRFRERSLSVPTDAGTTDMDYEEEQKVSEACALPYASTGSEGSNSADNITFLSVQQEAQHRRQRSKSISLKKAKKKPSPPTRSVSLVKDEPVLLPEGGSALPKDQRPRSLCLSLEHQGHHASHPNAQGHPAVPTFKDPEGAQFAHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREVSSPGRPAGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSGSGRVRPLVPERKSSLPPTSPMEKMSKSRLSFDLPLTSSTNLDLSGMSISIRSKTKVSRHHSDTNFGAKLAQKTSSNQPIMPMVTQSDLRSVRLRSISKSEPEDDIESPDYAEESGAEVLTLPERKMKPPIAEKPPLARRPPSLVYKPPSVPEEYPLTSPTLALTPKISIQHMRPLPQDIYTVVRKPKSSSCPEGRSPGESTAPSSLVFMPFASSSGAFFSGTQQPPQGSLEEEGPKGRALPERISLQSQEEVEKKKGKIPPPVPKKPSVLFLPLTSPTAQMEAYSAEPRLPLSPIITLEEDSKGLPTGDHLQSAGTRTISLPQADSEREASPLGSSGEPSTEEKSVISDKTAEWIVEDDDDVFVGSRTTEDLFTVIHRSKRKLLGWKEPGEAFASSSRPSSHSPIRNTAESPTSESAAPAGSSGGANLDAGRNDDFKALLQKKGSKATPRSRPSAAELLKTTNPLARRIIAQFSKDYETTDNPGT", "length": 1223, "header": "tr|A0A287B1Z4-1|A0A287B1Z4_PIG Isoform 1 of NHS like 2 OS=Sus scrofa OX=9823 GN=NHSL2 PE=4 SV=2 CANONICAL=A0A287B1Z4-1" }, "isoforms": [ { "isoform_ac": "A0A287AMZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z4/entry#A0A287AMZ6-1", "sequence": { "sequence": "MMGNSHHKQPRSKSQSRMHSATGHSNSPAGSVACSSTSDIRPSHSVPEGVHGRVAVGQETRFPHLTSPVLRNPSSDPEELLQSRGGTKPPGMEGMGMVYSVPSSCNGPTGSTFSTSWKGDAFTYMTPSAAAQSSQVSENGKSPSSGNSWASLHTLPPLIPKEAATLFVTRDTPAGCSGSAGYSEHPTQRRQVSERPSKVSLLTGGTSKLETGPGGASRFRERSLSVPTDAGTTDMDYEEEQKVSEACALPYASTGSEGSNSADNITFLSVQQEAQHRRQRSKSISLKKAKKKPSPPTRSVSLVKDEPVLLPEGGSALPKDQRPRSLCLSLEHQGHHASHPNAQGHPAVPTFKDPEGAQFAHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREVSSPGRPAGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSGSGRVRPLVPERKSSLPPTSPMEKMSKSRLSFDLPLTSSTNLDLSGMSISIRSKTKVSRHHSDTNFGAKLAQKTSSNQPIMPMVTQSDLRSVRLRSISKSEPEDDIESPDYAEESGAEVLTLPERKMKPPIAEKPPLARRPPSLVYKPPSVPEEYPLTSPTLALTPKISIQHMRPLPQDIYTVVRKPKSSSCPEGRSPGESTAPSSLVFMPFASSSGAFFSGTQQPPQGSLEEEGPKGRALPERISLQSQEEVEKKKGKIPPPVPKKPSVLFLPLTSPTAQMEAYSAEPRLPLSPIITLEEDSKGLPTGDHLQSAGTRTISLPQADSEREASPLGSSGEPSTEEKSVISDKTAEWIVEDDDDVFVGSRTTEDLFTVIHRSKRKLLGWKEPGEAFASSSRPSSHSPIRNTAESPTSESAAPAGSSGGANLDAGRNDDFKALLQKKGSKATPRSRPSAAELLKTTNPLARRIIAQFSKDYETTDNPGT", "length": 950, "header": "tr|A0A287AMZ6-1|A0A287B1Z4_PIG Computationally mapped isoform of NHS like 2 OS=Sus scrofa OX=9823 GN=NHSL2 PE=4 SV=1 CANONICAL=A0A287B1Z4-1" }, "locus": { "chromosome": "X", "start_pos": 58025719, "end_pos": 57939602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049498.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049498.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045298.1", "url": "https://www.ensembl.org/id/ENSSSCP00000045298.1" } ] } }, { "isoform_ac": "A0A287B1Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z4/entry#A0A287B1Z4-1", "sequence": { "sequence": "MPFYRRTVVPQRLCPRNPPQPLTELRDVSHLAALSLLRQLADLCGHSLALLEDLEGHLLALGRRTDSLFRRTVRLRRRLPCRLLGPEDDDEELAAANSGRENATATAHSRSSWRQPVNVFLSSGRPPSVEELLREAQLNLQSLLQEEYEEQYSEARLLGQTFRSADEAPEPTPSPRPQSARRLEFVLMPTKWQLNEDETTTQGVRAPEASLRPTTDKQAAWNSPFPLPVLEEKRWLQPCPMHSDIVPINVSGQQFDKHASLRQSLFNTETAVNPKSTLRRRRTIIGFSNYSQRDQGHSNSPAGSVACSSTSDIRPSHSVPEGVHGRVAVGQETRFPHLTSPVLRNPSSDPEELLQSRGGTKPPGMEGMGMVYSVPSSCNGPTGSTFSTSWKGDAFTYMTPSAAAQSSQVSENGKSPSSGNSWASLHTLPPLIPKEAATLFVTRDTPAGCSGSAGYSEHPTQRRQVSERPSKVSLLTGGTSKLETGPGGASRFRERSLSVPTDAGTTDMDYEEEQKVSEACALPYASTGSEGSNSADNITFLSVQQEAQHRRQRSKSISLKKAKKKPSPPTRSVSLVKDEPVLLPEGGSALPKDQRPRSLCLSLEHQGHHASHPNAQGHPAVPTFKDPEGAQFAHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREVSSPGRPAGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSGSGRVRPLVPERKSSLPPTSPMEKMSKSRLSFDLPLTSSTNLDLSGMSISIRSKTKVSRHHSDTNFGAKLAQKTSSNQPIMPMVTQSDLRSVRLRSISKSEPEDDIESPDYAEESGAEVLTLPERKMKPPIAEKPPLARRPPSLVYKPPSVPEEYPLTSPTLALTPKISIQHMRPLPQDIYTVVRKPKSSSCPEGRSPGESTAPSSLVFMPFASSSGAFFSGTQQPPQGSLEEEGPKGRALPERISLQSQEEVEKKKGKIPPPVPKKPSVLFLPLTSPTAQMEAYSAEPRLPLSPIITLEEDSKGLPTGDHLQSAGTRTISLPQADSEREASPLGSSGEPSTEEKSVISDKTAEWIVEDDDDVFVGSRTTEDLFTVIHRSKRKLLGWKEPGEAFASSSRPSSHSPIRNTAESPTSESAAPAGSSGGANLDAGRNDDFKALLQKKGSKATPRSRPSAAELLKTTNPLARRIIAQFSKDYETTDNPGT", "length": 1223, "header": "tr|A0A287B1Z4-1|A0A287B1Z4_PIG Isoform 1 of NHS like 2 OS=Sus scrofa OX=9823 GN=NHSL2 PE=4 SV=2 CANONICAL=A0A287B1Z4-1" }, "locus": { "chromosome": "X", "start_pos": 58025719, "end_pos": 57742279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060008.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060008.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050107.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050107.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 172, "start_aa": "Thr", "end_pos": 172, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr172", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 382, "start_aa": "Thr", "end_pos": 382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr382", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 721, "start_aa": "Thr", "end_pos": 721, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr721", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 723, "start_aa": "Thr", "end_pos": 723, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr723", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AMZ6", "url": "https://www.uniprot.org/uniprotkb/A0A287AMZ6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Z4", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1Z4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1223, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1Z4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1Z4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 172, 382, 721, 723 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 289, "end_pos": 291 }, { "start_pos": 537, "end_pos": 539 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B282-1", "uniprot_ac": "A0A287B282", "uniprot_id": "A0A287B282_PIG", "mass": { "chemical_mass": 60102.0, "monoisotopic_mass": 60102.0 }, "refseq": {}, "gene_names": [ { "name": "HNRNPLL", "type": "recommended", "evidence": [ { "id": "A0A287B282", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B282" } ] } ], "protein_names": [ { "name": "Heteroous nuclear ribonucleoprotein L like", "type": "synonym", "evidence": [ { "id": "A0A287B282", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B282/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B282", "url": "https://www.uniprot.org/uniprotkb/A0A287B282" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HNRNPLL", "url": "https://www.uniprot.org/uniprotkb/A0A287B282", "locus": { "chromosome": "3", "start_pos": 101802062, "end_pos": 101753292, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000020878", "url": "https://www.ensembl.org/id/ENSSSCG00000020878" } ] } } ], "crossref": [ { "id": "A0A287B282", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B282", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000020878", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000020878", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12700", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12700", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12705", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12705", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12781", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12781", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12786", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12786", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100622737", "url": "https://www.ncbi.nlm.nih.gov/gene/100622737", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AR71", "url": "https://www.uniprot.org/uniprotkb/A0A287AR71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AR71-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AR71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXH8", "url": "https://www.uniprot.org/uniprotkb/A0A287AXH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B282", "url": "https://www.uniprot.org/uniprotkb/A0A287B282", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B282-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B282-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A287BLJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BLJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQJ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L8B8", "url": "https://www.uniprot.org/uniprotkb/I3L8B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L8B8-1", "url": "https://www.uniprot.org/uniprotkb/I3L8B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LG16", "url": "https://www.uniprot.org/uniprotkb/I3LG16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LG16-1", "url": "https://www.uniprot.org/uniprotkb/I3LG16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSSSSPRETYEEDREYESQAKRLKTEEGEIDYSAEEGENRREATPRSGGDGSGGRSFSQPEAGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMLMFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGRRDRGKGRQRQAILGEHPSSFRHDGYGSHGPLLPLPSRYRMGSRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPNGSNPYTLKLCFSTSSHL", "length": 541, "header": "tr|A0A287B282-1|A0A287B282_PIG Isoform 1 of Heteroous nuclear ribonucleoprotein L like OS=Sus scrofa OX=9823 GN=HNRNPLL PE=1 SV=3 CANONICAL=A0A287B282-1" }, "isoforms": [ { "isoform_ac": "A0A287AR71-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B282/entry#A0A287AR71-1", "sequence": { "sequence": "MSSSSSSPRETYEEDREYESQAKRLKTEEGEIDYSAEEGENRREATPRSGGDGSGGRSFSQPEAGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMVDRLNVIRNDNDSWDYTKPYLGRRDRGKGRQRQAILGEHPSSFRHDGYGSHGPLLPLPSRYRMGSRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPNGSNPYTLKLCFSTSSHL", "length": 507, "header": "tr|A0A287AR71-1|A0A287B282_PIG Computationally mapped isoform of Heteroous nuclear ribonucleoprotein L like OS=Sus scrofa OX=9823 GN=HNRNPLL PE=1 SV=2 CANONICAL=A0A287B282-1" }, "locus": { "chromosome": "3", "start_pos": 101794344, "end_pos": 101753684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059400.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059400.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046447.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046447.2" } ] } }, { "isoform_ac": "A0A287AXH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B282/entry#A0A287AXH8-1", "sequence": { "sequence": "MSSSSSSPRETYEEDREYESQAKRLKTEEGEIDYSAEEGENRREATPRSGGDGSGGRSFSQPEAGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMLMFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGRRGSHGPLLPLPSRYRMGSRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPRQFPHSREHKDLYFDGSNPYTLKLCFSTSSHL", "length": 531, "header": "tr|A0A287AXH8-1|A0A287B282_PIG Computationally mapped isoform of Heteroous nuclear ribonucleoprotein L like OS=Sus scrofa OX=9823 GN=HNRNPLL PE=1 SV=2 CANONICAL=A0A287B282-1" }, "locus": { "chromosome": "3", "start_pos": 101794344, "end_pos": 101753684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065400.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065400.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048581.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048581.2" } ] } }, { "isoform_ac": "A0A287B282-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B282/entry#A0A287B282-1", "sequence": { "sequence": "MSSSSSSPRETYEEDREYESQAKRLKTEEGEIDYSAEEGENRREATPRSGGDGSGGRSFSQPEAGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMLMFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGRRDRGKGRQRQAILGEHPSSFRHDGYGSHGPLLPLPSRYRMGSRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPNGSNPYTLKLCFSTSSHL", "length": 541, "header": "tr|A0A287B282-1|A0A287B282_PIG Isoform 1 of Heteroous nuclear ribonucleoprotein L like OS=Sus scrofa OX=9823 GN=HNRNPLL PE=1 SV=3 CANONICAL=A0A287B282-1" }, "locus": { "chromosome": "3", "start_pos": 101794344, "end_pos": 101753684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036773.3", "url": "https://www.ensembl.org/id/ENSSSCT00000036773.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050356.3", "url": "https://www.ensembl.org/id/ENSSSCP00000050356.3" } ] } }, { "isoform_ac": "A0A287BLJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B282/entry#A0A287BLJ8-1", "sequence": { "sequence": "MSSSSSSPRETYEEDREYESQAKRLKTEEGEIDYSAEEGENRREATPRSGGDGSGGRSFSQPEAGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMLMFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGRRDRGKGRQRQAILGEHPSSFRHDGYGSHGPLLPLPSRYRMGSRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPSKLNRLSWVAVAQDLSL", "length": 540, "header": "tr|A0A287BLJ8-1|A0A287BLJ8_PIG Computationally mapped isoform of Heteroous nuclear ribonucleoprotein L like OS=Sus scrofa OX=9823 GN=HNRNPLL PE=1 SV=1 CANONICAL=A0A287B282-1" }, "locus": { "chromosome": "3", "start_pos": 101791010, "end_pos": 101753684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048190.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048190.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056944.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056944.2" } ] } }, { "isoform_ac": "A0A5G2QQJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B282/entry#A0A5G2QQJ1-1", "sequence": { "sequence": "MSSSSSSPRETYEEDREYESQAKRLKTEEGEIDYSAEEGENRREATPRSGGDGSGGRSFSQPEAGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMLMFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGRRDRGKGRQRQAILGEHPSSFRHDGYGSHGPLLPLPSRYRMGSRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPSKLNLTYCFTTSYHMCT", "length": 540, "header": "tr|A0A5G2QQJ1-1|A0A287B282_PIG Computationally mapped isoform of Heteroous nuclear ribonucleoprotein L like OS=Sus scrofa OX=9823 GN=HNRNPLL PE=1 SV=1 CANONICAL=A0A287B282-1" }, "locus": { "chromosome": "3", "start_pos": 101790919, "end_pos": 101753684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074023.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074023.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064335.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064335.1" } ] } }, { "isoform_ac": "I3L8B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B282/entry#I3L8B8-1", "sequence": { "sequence": "MSSSSSSPRETYEEDREYESQAKRLKTEEGEIDYSAEEGENRREATPRSGGDGSGGRSFSQPEAGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGRRDRGKGRQRQAILGEHPSSFRHDGYGSHGPLLPLPSRYRMGSRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPMPYNLLQSWI", "length": 533, "header": "tr|I3L8B8-1|A0A287B282_PIG Computationally mapped isoform of Heteroous nuclear ribonucleoprotein L like OS=Sus scrofa OX=9823 GN=HNRNPLL PE=1 SV=2 CANONICAL=A0A287B282-1" }, "locus": { "chromosome": "3", "start_pos": 101792570, "end_pos": 101753684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030162.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030162.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020278.2", "url": "https://www.ensembl.org/id/ENSSSCP00000020278.2" } ] } }, { "isoform_ac": "I3LG16-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B282/entry#I3LG16-1", "sequence": { "sequence": "MSSSSSSPRETYEEDREYESQAKRLKTEEGEIDYSAEEGENRREATPRSGGDGSGGRSFSQPEAGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMLMFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGRRDRGKGRQRQAILGEHPSSFRHDGYGSHGPLLPLPSRYRMGSRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPTVVTLGAKAAALPDQGIQCTLSAA", "length": 547, "header": "tr|I3LG16-1|A0A287B282_PIG Computationally mapped isoform of Heteroous nuclear ribonucleoprotein L like OS=Sus scrofa OX=9823 GN=HNRNPLL PE=1 SV=3 CANONICAL=A0A287B282-1" }, "locus": { "chromosome": "3", "start_pos": 101802059, "end_pos": 101753684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024049.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024049.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023009.3", "url": "https://www.ensembl.org/id/ENSSSCP00000023009.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQJ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQJ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A287B282", "url": "https://www.uniprot.org/uniprotkb/A0A287B282" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A287B282", "url": "https://www.uniprot.org/uniprotkb/A0A287B282" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A287B282", "url": "https://www.uniprot.org/uniprotkb/A0A287B282" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A287B282", "url": "https://www.uniprot.org/uniprotkb/A0A287B282" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A287B282", "url": "https://www.uniprot.org/uniprotkb/A0A287B282" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A287B282", "url": "https://www.uniprot.org/uniprotkb/A0A287B282" } ], "pmid": "" }, { "name": "positive regulation of RNA splicing", "id": "GO:0033120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033120", "evidence": [ { "database": "UniProtKB", "id": "A0A287B282", "url": "https://www.uniprot.org/uniprotkb/A0A287B282" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A287B282", "url": "https://www.uniprot.org/uniprotkb/A0A287B282" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B282-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 541, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B282-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B282" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B282", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B282" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 149, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 524, "end_pos": 526 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B0H3-1", "uniprot_ac": "A0A287B0H3", "uniprot_id": "A0A287B0H3_PIG", "mass": { "chemical_mass": 13134.0, "monoisotopic_mass": 13134.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Transmembrane protein 230", "type": "recommended", "evidence": [ { "id": "A0A287B0H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B0H3", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H3", "locus": {} } ], "crossref": [ { "id": "A0A287B0H3", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B0H3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000035546", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035546", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR044234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15664", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15664", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15664:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15664:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A287B0H3", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLSRTNLTTGIPSSKVKYSRFSSTDDGYTDLQFKKSPPTIPYKAIALATVLFLISAFLIIIGSLLLAGYISKGGADRSVPVLIIGIWGRIGAVATGLRQSHSNAGSEPRLQPTPQLTATPDR", "length": 123, "header": "tr|A0A287B0H3-1|A0A287B0H3_PIG Isoform 1 of Transmembrane protein 230 OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A287B0H3-1" }, "isoforms": [ { "isoform_ac": "A0A287B0H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H3/entry#A0A287B0H3-1", "sequence": { "sequence": "MMLSRTNLTTGIPSSKVKYSRFSSTDDGYTDLQFKKSPPTIPYKAIALATVLFLISAFLIIIGSLLLAGYISKGGADRSVPVLIIGIWGRIGAVATGLRQSHSNAGSEPRLQPTPQLTATPDR", "length": 123, "header": "tr|A0A287B0H3-1|A0A287B0H3_PIG Isoform 1 of Transmembrane protein 230 OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A287B0H3-1" }, "locus": { "chromosome": "15", "start_pos": 59946605, "end_pos": 59945193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037902.2", "url": "https://www.ensembl.org/id/ENSSSCT00000037902.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049902.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049902.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 114, "start_aa": "Thr", "end_pos": 114, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr114", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0H3", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0H3", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H3" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0H3", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "synaptic vesicle transport", "id": "GO:0048489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048489", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0H3", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B0H3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 123, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B0H3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B0H3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 114 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B0I9-1", "uniprot_ac": "A0A287B0I9", "uniprot_id": "A0A287B0I9_PIG", "mass": { "chemical_mass": 16026.0, "monoisotopic_mass": 16026.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A287B0I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0I9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B0I9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0I9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A287B0I9", "locus": {} } ], "crossref": [ { "id": "A0A287B0I9", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B0I9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000031752", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031752", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04983", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04983", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19343", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19343", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19343:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19343:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B0I9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0I9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKILGASFLVLWLQLGWVSGQQKEKRDQQQVKQSSQPLTVQEGDISILNCTYENSAFDYFPWYRQHPGKGPELLIAARSSSITEEDGRLRVSLSQSAKHVSLHINASQPGDSATYFCAASAQCSPGTCSLYPNLQLRLQPNPAV", "length": 145, "header": "tr|A0A287B0I9-1|A0A287B0I9_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A287B0I9-1" }, "isoforms": [ { "isoform_ac": "A0A287B0I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0I9/entry#A0A287B0I9-1", "sequence": { "sequence": "MDKILGASFLVLWLQLGWVSGQQKEKRDQQQVKQSSQPLTVQEGDISILNCTYENSAFDYFPWYRQHPGKGPELLIAARSSSITEEDGRLRVSLSQSAKHVSLHINASQPGDSATYFCAASAQCSPGTCSLYPNLQLRLQPNPAV", "length": 145, "header": "tr|A0A287B0I9-1|A0A287B0I9_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A287B0I9-1" }, "locus": { "chromosome": "7", "start_pos": 77277685, "end_pos": 77277122, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047290.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047290.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049917.1", "url": "https://www.ensembl.org/id/ENSSSCP00000049917.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0I9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0I9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0I9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0I9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptide antigen binding", "id": "GO:0042605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042605", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0I9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0I9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0I9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0I9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B0I9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 145, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B0I9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B0I9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B0I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0I9" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 121, "start_aa": "Gln", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B0L5-1", "uniprot_ac": "A0A287B0L5", "uniprot_id": "A0A287B0L5_PIG", "mass": { "chemical_mass": 42666.0, "monoisotopic_mass": 42666.0 }, "refseq": { "ac": "NP_001230324", "name": "WD repeat-containing protein 74", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230324" }, "gene_names": [ { "name": "WDR74", "type": "recommended", "evidence": [ { "id": "A0A287B0L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5" } ] }, { "name": "WDR74", "type": "synonym", "evidence": [ { "id": "NP_001230324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230324" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 74", "type": "recommended", "evidence": [ { "id": "A0A287B0L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 74", "type": "synonym", "evidence": [ { "id": "NP_001230324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230324" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B0L5", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "WDR74", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5", "locus": { "chromosome": "2", "start_pos": 8936906, "end_pos": 8931495, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000028025", "url": "https://www.ensembl.org/id/ENSSSCG00000028025" } ] } } ], "crossref": [ { "id": "ENSSSCG00000028025", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000028025", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22857", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22857", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100627951", "url": "https://www.ncbi.nlm.nih.gov/gene/100627951", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100627951", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627951", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B0L5", "url": "https://www.orthodb.org/?gene=A0A287B0L5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16038", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16038", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16038:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16038:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001230324", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230324", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B0L5", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1BZP0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1BZP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1BZP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1BZP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAEARWNHVWVGTDTGILKGVNLQRKQAVNYTAAGQPQREEAVSALCWGAGGETQILVGCADRTVKLFSTEEGRFQGQRHCPGGEGTFRGLAQVDGTLITCVESGILRVWHDNDKEASSDPLLELRVGPGVCRMRQDPSRPHVVATGGKENALKVWDLQGSEEPVFKAKNVRNDWLDLRVPIWDQDIQFLPESQKLVTCTGYHQVRVYDPASPQRRPVLEATYGEYPLTAMTLTPEGNSVIVGNTHGQLAEIDLRQGRLLGCLKGLAGSVRGLQCHPSKPLLASCGLDRVLRVHRIRNPRGLEHKVYLKSQLNCLLLSGRDNWEDEPQEPQQPNEVPSEDTETDELWASLEAAAKRKLPDLEQTQGVLQTRKRKKKRPGSTNS", "length": 385, "header": "tr|A0A287B0L5-1|A0A287B0L5_PIG Isoform 1 of WD repeat-containing protein 74 OS=Sus scrofa OX=9823 GN=WDR74 PE=4 SV=2 CANONICAL=A0A287B0L5-1" }, "isoforms": [ { "isoform_ac": "A0A287B0L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5/entry#A0A287B0L5-1", "sequence": { "sequence": "MAAAEARWNHVWVGTDTGILKGVNLQRKQAVNYTAAGQPQREEAVSALCWGAGGETQILVGCADRTVKLFSTEEGRFQGQRHCPGGEGTFRGLAQVDGTLITCVESGILRVWHDNDKEASSDPLLELRVGPGVCRMRQDPSRPHVVATGGKENALKVWDLQGSEEPVFKAKNVRNDWLDLRVPIWDQDIQFLPESQKLVTCTGYHQVRVYDPASPQRRPVLEATYGEYPLTAMTLTPEGNSVIVGNTHGQLAEIDLRQGRLLGCLKGLAGSVRGLQCHPSKPLLASCGLDRVLRVHRIRNPRGLEHKVYLKSQLNCLLLSGRDNWEDEPQEPQQPNEVPSEDTETDELWASLEAAAKRKLPDLEQTQGVLQTRKRKKKRPGSTNS", "length": 385, "header": "tr|A0A287B0L5-1|A0A287B0L5_PIG Isoform 1 of WD repeat-containing protein 74 OS=Sus scrofa OX=9823 GN=WDR74 PE=4 SV=2 CANONICAL=A0A287B0L5-1" }, "locus": { "chromosome": "2", "start_pos": 8936864, "end_pos": 8931539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048273.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048273.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049652.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049652.2" } ] } }, { "isoform_ac": "A0A8D1BZP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5/entry#A0A8D1BZP0-1", "sequence": { "sequence": "MAAAEARWNHVWVGTDTGILKGVNLQRKQAVNYTAAGQPQREEAVSALCWGAGGETQILVGCADRTVKLFSTEEGRFQGQRHCPGGEGTFRGLAQVDGTLITCVESGILRVWHDNDKEASSDPLLELRVGPGVCRMRQDPSRPHVVATGGKENALKVWDLQGSEEPVFKAKNVRNDWLDLRVPIWDQDIQFLPESQKLVTCTGYHQVRVYDPASPQRRPVLEATYGEYPLTAMTLTPEGNSVIVGNTHGQLAEIDLRQGRLLGCLKGLAGSVRGLQCHPSKPLLASCGLDRVLRVHRIRNPRGLEHKDEPQEPQQPNEVPSEDTETDELWASLEAAAKRKLPDLEQTQGVLQTRKRKKKRPGSTNS", "length": 366, "header": "tr|A0A8D1BZP0-1|A0A287B0L5_PIG Computationally mapped isoform of WD repeat-containing protein 74 OS=Sus scrofa OX=9823 GN=WDR74 PE=4 SV=1 CANONICAL=A0A287B0L5-1" }, "locus": { "chromosome": "2", "start_pos": 8936864, "end_pos": 8931539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037103.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037103.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046467.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046467.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1BZP0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1BZP0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100627951", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627951", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0L5", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0L5", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0L5", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0L5", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0L5", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5" } ], "pmid": "" }, { "name": "RNA metabolic process", "id": "GO:0016070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016070", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0L5", "url": "https://www.uniprot.org/uniprotkb/A0A287B0L5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1X5-1", "uniprot_ac": "A0A287B1X5", "uniprot_id": "A0A287B1X5_PIG", "mass": { "chemical_mass": 23318.0, "monoisotopic_mass": 23318.0 }, "refseq": {}, "gene_names": [ { "name": "TPD52L2", "type": "recommended", "evidence": [ { "id": "A0A287B1X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X5" } ] } ], "protein_names": [ { "name": "TPD52 like 2", "type": "synonym", "evidence": [ { "id": "A0A287B1X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1X5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TPD52L2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X5", "locus": { "chromosome": "17", "start_pos": 62750557, "end_pos": 62733593, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036712", "url": "https://www.ensembl.org/id/ENSSSCG00000036712" } ] } } ], "crossref": [ { "id": "A0A287B1X5", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1X5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000036712", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036712", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SDAMMDV", "url": "https://omabrowser.org/oma/group/SDAMMDV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19307", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19307", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19307:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19307:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B0P4", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1X5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q979", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q979", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q979-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q979-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSAGQDINLNSPNKGLLSDSMTDVPVDTAQTPVEGLTEAEAEELRAELAKVEEEIVTLRQVLAAKERHCGELRRKLGLSALEGLRQNLSRSWQDVQGSSAYMKTSEKLGEWNEKVTQSDLYKKTQETLSQAGQKTSAALSTMGSAISRKLGDMSSSSIRHSISMPAMRNSATFKSFEDRVGTIKSKVVGGRENGGDNLPSPAGSGDKPLPDRTSF", "length": 216, "header": "tr|A0A287B1X5-1|A0A287B1X5_PIG Isoform 1 of TPD52 like 2 OS=Sus scrofa OX=9823 GN=TPD52L2 PE=1 SV=2 CANONICAL=A0A287B1X5-1" }, "isoforms": [ { "isoform_ac": "A0A287B0P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X5/entry#A0A287B0P4-1", "sequence": { "sequence": "LDCADINLNSPNKGLLSDSMTDVPVDTAQTPVEGLTEAEAEELRAELAKVEEEIVTLRQVLAAKERHCGELRRKLGLSALEGLRQNLSRSWQDVQGSSAYMKTSEKLGEWNEKVTQSDLYKKTQETLSQAGQKTSAALSTMGSAISRKLGDMSSSSIRHSISMPAMRNSATFKSFEDRVGTIKSKVVGGRENGGDNLPSPAGSGDKPLPDRTSF", "length": 214, "header": "tr|A0A287B0P4-1|A0A287B1X5_PIG Computationally mapped isoform of TPD52 like 2 OS=Sus scrofa OX=9823 GN=TPD52L2 PE=1 SV=2 CANONICAL=A0A287B1X5-1" }, "locus": { "chromosome": "17", "start_pos": 62749142, "end_pos": 62736582, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042336.2", "url": "https://www.ensembl.org/id/ENSSSCT00000042336.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049989.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049989.2" } ] } }, { "isoform_ac": "A0A287B1X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X5/entry#A0A287B1X5-1", "sequence": { "sequence": "MDSAGQDINLNSPNKGLLSDSMTDVPVDTAQTPVEGLTEAEAEELRAELAKVEEEIVTLRQVLAAKERHCGELRRKLGLSALEGLRQNLSRSWQDVQGSSAYMKTSEKLGEWNEKVTQSDLYKKTQETLSQAGQKTSAALSTMGSAISRKLGDMSSSSIRHSISMPAMRNSATFKSFEDRVGTIKSKVVGGRENGGDNLPSPAGSGDKPLPDRTSF", "length": 216, "header": "tr|A0A287B1X5-1|A0A287B1X5_PIG Isoform 1 of TPD52 like 2 OS=Sus scrofa OX=9823 GN=TPD52L2 PE=1 SV=2 CANONICAL=A0A287B1X5-1" }, "locus": { "chromosome": "17", "start_pos": 62749142, "end_pos": 62733707, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042547.2", "url": "https://www.ensembl.org/id/ENSSSCT00000042547.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050409.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050409.2" } ] } }, { "isoform_ac": "A0A5G2Q979-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X5/entry#A0A5G2Q979-1", "sequence": { "sequence": "MDSAGQDINLNSPNKGLLSDSMTDVPVDTAQTPVEGLTEAEAEELRAELAKVEEEIVTLRQVLAAKERHCGELRRKLGLSALEGLRQNLSRSWQDVQGSSAYKKTQETLSQAGQKTSAALSTMGSAISRKLGDMSSSSIRHSISMPAMRNSATFKSFEDRVGTIKSKVVGGRENGGDNLPSPAGSGDKPLPDRTSF", "length": 196, "header": "tr|A0A5G2Q979-1|A0A287B1X5_PIG Computationally mapped isoform of TPD52 like 2 OS=Sus scrofa OX=9823 GN=TPD52L2 PE=1 SV=1 CANONICAL=A0A287B1X5-1" }, "locus": { "chromosome": "17", "start_pos": 62749142, "end_pos": 62733707, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076679.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076679.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059852.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059852.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2Q979", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q979" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B964-1", "protein_name": "Tpd52 like 2b isoform X4", "gene_name": "tpd52l2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDTANQDINLNSPHKGLGSDSISDLPEERGAAAVSPGTLPPGLTEEEAEELRLELTKVEEEINTLRQVLSAKERHASELKRKLGLSPLTEFKQNITKSWQDVQTSNAYLSASSTLDDITSSEVYKKTQETLSQAGQKTSAALSTVGTAISRKLGDMRALPFSNSFGSNYSIRHSISMPTMRNSPTFKSFEDKVGNIKYKVVGGKANGESAHSPNESEPAQENAPF", "length": 225 }, "evidence": [ { "id": "A0A287B1X5", "url": "https://omabrowser.org/oma/group/A0A287B1X5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O43399-1", "protein_name": "Tumor protein D54", "gene_name": "TPD52L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSAGQDINLNSPNKGLLSDSMTDVPVDTGVAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELKQNLSRSWHDVQVSSAYVKTSEKLGEWNEKVTQSDLYKKTQETLSQAGQKTSAALSTVGSAISRKLGDMRNSATFKSFEDRVGTIKSKVVGDRENGSDNLPSSAGSGDKPLSDPAPF", "length": 206 }, "evidence": [ { "id": "A0A287B1X5", "url": "https://omabrowser.org/oma/group/A0A287B1X5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CYZ2-1", "protein_name": "Tumor protein D54", "gene_name": "Tpd52l2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSASQDINLNSPNKGVLSDFMTDVPVDPGVVHRTPVVEGLTEGEEEELRAELAKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELKQNLSRSWHDVQVSTAYVKTSEKLGEWNEKVTQSDLYKKTQETLSQAGQKTSAALSTMGSAISRKLGDMSSYSIRHSISMPVMRNSATFKSFEDRVGTIKSKVVGGRENGSDNLPPSPGSGDQTLPDHAPF", "length": 220 }, "evidence": [ { "id": "A0A287B1X5", "url": "https://omabrowser.org/oma/group/A0A287B1X5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1X5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1X5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1X5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 216, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1X5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1X5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B0P9-1", "uniprot_ac": "A0A287B0P9", "uniprot_id": "A0A287B0P9_PIG", "mass": { "chemical_mass": 43764.0, "monoisotopic_mass": 43764.0 }, "refseq": {}, "gene_names": [ { "name": "MEI4", "type": "recommended", "evidence": [ { "id": "A0A287B0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9" } ] } ], "protein_names": [ { "name": "Meiotic double-stranded break formation protein 4", "type": "synonym", "evidence": [ { "id": "A0A287B0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MEI4", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9", "locus": { "chromosome": "1", "start_pos": 88189903, "end_pos": 88399137, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034152", "url": "https://www.ensembl.org/id/ENSSSCG00000034152" } ] } } ], "crossref": [ { "id": "A0A287B0P9", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B0P9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034152", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034152", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR025888", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025888", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR28575", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28575", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28575:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28575:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13971", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13971", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDQAWFLRTSKLALALAIIRSKPADQSSREYTEHLARVVSGQESKWRSKVEALEAEVLQLRQKLLLSRICSGPIKTGDPSSQLQAQERRSSENTPTLLEDSGCDLSSEQRIEPSEMPPWFVESCLPTPFPPLPIVDRCHLAPENPLSSSMQFLQHLLELKNLTESGSLKTDLSHFENDSSTVSESAFRLLDGLITFYQEPKLPCSSFWTEAVGTLAKLISDSNLSNHILKKCSKKLEEFEKTLLQVILKNSHINRFQVQHHVSQSLVTLGSCSLLRKSIISLLLSEVNSFAADLGAINQEQANHDVTRYENVFFVFWVLEQLLQKETQEGNTSRILREDQEIKTFLQKHDETIFQLSDAFPLFTFYLWRLGVLLNSVEIETVKE", "length": 385, "header": "tr|A0A287B0P9-1|A0A287B0P9_PIG Isoform 1 of Meiotic double-stranded break formation protein 4 OS=Sus scrofa OX=9823 GN=MEI4 PE=3 SV=2 CANONICAL=A0A287B0P9-1" }, "isoforms": [ { "isoform_ac": "A0A287B0P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9/entry#A0A287B0P9-1", "sequence": { "sequence": "MDDQAWFLRTSKLALALAIIRSKPADQSSREYTEHLARVVSGQESKWRSKVEALEAEVLQLRQKLLLSRICSGPIKTGDPSSQLQAQERRSSENTPTLLEDSGCDLSSEQRIEPSEMPPWFVESCLPTPFPPLPIVDRCHLAPENPLSSSMQFLQHLLELKNLTESGSLKTDLSHFENDSSTVSESAFRLLDGLITFYQEPKLPCSSFWTEAVGTLAKLISDSNLSNHILKKCSKKLEEFEKTLLQVILKNSHINRFQVQHHVSQSLVTLGSCSLLRKSIISLLLSEVNSFAADLGAINQEQANHDVTRYENVFFVFWVLEQLLQKETQEGNTSRILREDQEIKTFLQKHDETIFQLSDAFPLFTFYLWRLGVLLNSVEIETVKE", "length": 385, "header": "tr|A0A287B0P9-1|A0A287B0P9_PIG Isoform 1 of Meiotic double-stranded break formation protein 4 OS=Sus scrofa OX=9823 GN=MEI4 PE=3 SV=2 CANONICAL=A0A287B0P9-1" }, "locus": { "chromosome": "1", "start_pos": 88359051, "end_pos": 88189903, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060382.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060382.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048336.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048336.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9" } ], "pmid": "" }, { "name": "meiotic DNA double-strand break formation", "id": "GO:0042138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042138", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "lateral element", "id": "GO:0000800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000800", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0P9", "url": "https://www.uniprot.org/uniprotkb/A0A287B0P9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B0P9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 385, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B0P9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B0P9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 178, "end_pos": 180 }, { "start_pos": 224, "end_pos": 226 }, { "start_pos": 332, "end_pos": 334 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B0Q2-1", "uniprot_ac": "A0A287B0Q2", "uniprot_id": "A0A287B0Q2_PIG", "mass": { "chemical_mass": 11631.0, "monoisotopic_mass": 11631.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A287B0Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Q2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B0Q2", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Q2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Q2", "locus": {} } ], "crossref": [ { "id": "A0A287B0Q2", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B0Q2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034861", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034861", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "A0A287B0Q2", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "FGLLFCHLILRAAIRMAKDVLDPLRQVLDRGMQSNKSYQRPWPLGFSRFCSCGFHGCTSFLGPLPHLSSFALQPVHWLLPPHCSNGTEVSQKMAAEDSDHSCMS", "length": 104, "header": "tr|A0A287B0Q2-1|A0A287B0Q2_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A287B0Q2-1" }, "isoforms": [ { "isoform_ac": "A0A287B0Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Q2/entry#A0A287B0Q2-1", "sequence": { "sequence": "FGLLFCHLILRAAIRMAKDVLDPLRQVLDRGMQSNKSYQRPWPLGFSRFCSCGFHGCTSFLGPLPHLSSFALQPVHWLLPPHCSNGTEVSQKMAAEDSDHSCMS", "length": 104, "header": "tr|A0A287B0Q2-1|A0A287B0Q2_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A287B0Q2-1" }, "locus": { "chromosome": "X", "start_pos": 45582869, "end_pos": 45580586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047412.2", "url": "https://www.ensembl.org/id/ENSSSCT00000047412.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049799.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049799.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0Q2", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Q2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B0Q2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 104, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B0Q2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B0Q2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 35, "end_pos": 37 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B0T4-1", "uniprot_ac": "A0A287B0T4", "uniprot_id": "A0A287B0T4_PIG", "mass": { "chemical_mass": 35301.0, "monoisotopic_mass": 35301.0 }, "refseq": { "ac": "XP_005653898", "name": "transmembrane protein 255B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653898" }, "gene_names": [ { "name": "TMEM255B", "type": "recommended", "evidence": [ { "id": "A0A287B0T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0T4" } ] }, { "name": "TMEM255B", "type": "synonym", "evidence": [ { "id": "XP_005653898", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653898" } ] } ], "protein_names": [ { "name": "Transmembrane protein 255B", "type": "synonym", "evidence": [ { "id": "A0A287B0T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0T4/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 255B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005653898", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653898" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B0T4", "url": "https://www.uniprot.org/uniprotkb/A0A287B0T4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMEM255B", "url": "https://www.uniprot.org/uniprotkb/A0A287B0T4", "locus": { "chromosome": "11", "start_pos": 78837980, "end_pos": 78816867, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009564", "url": "https://www.ensembl.org/id/ENSSSCG00000009564" } ] } } ], "crossref": [ { "id": "ENSSSCG00000009564", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009564", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100738464", "url": "https://www.ncbi.nlm.nih.gov/gene/100738464", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100738464", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738464", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SHYYEFT", "url": "https://omabrowser.org/oma/group/SHYYEFT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287B0T4", "url": "https://www.orthodb.org/?gene=A0A287B0T4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33721", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33721", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33721:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33721:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14967", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14967", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005653898", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653898", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B0T4", "url": "https://www.uniprot.org/uniprotkb/A0A287B0T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0T4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPLQPPAPRPLALLDTTEGFARRKKTSLWFVGSLLVVSTFILTLGLTANTRTENVAVGGYYPGIVLGFGSFLGIIGIHLVENRRQMLVAAVVFISFGVVAAFCCAIVDGVFAARHIEPRPLVAGRCQFYSSEVGYLHDVYQTEVTCHSLNGQCQLKVKGDTCYCCDLYNCQSAEHPATYYEFVGVSSCQDVLHLYRLLWASAVLNVLGLFLGIVTAAVLGAFKDMVPLSQLAYGPSSPPQTLYNPAQQILAYAGFCQAPPAGAPCSSFPLPLQPSCTFTASPRTDLSLSEDVWLPSQSSSGCRLPPNAPPVSAPTCFLPGEKPPPYAP", "length": 329, "header": "tr|A0A287B0T4-1|A0A287B0T4_PIG Isoform 1 of Transmembrane protein 255B OS=Sus scrofa OX=9823 GN=TMEM255B PE=3 SV=1 CANONICAL=A0A287B0T4-1" }, "isoforms": [ { "isoform_ac": "A0A287B0T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0T4/entry#A0A287B0T4-1", "sequence": { "sequence": "MQPLQPPAPRPLALLDTTEGFARRKKTSLWFVGSLLVVSTFILTLGLTANTRTENVAVGGYYPGIVLGFGSFLGIIGIHLVENRRQMLVAAVVFISFGVVAAFCCAIVDGVFAARHIEPRPLVAGRCQFYSSEVGYLHDVYQTEVTCHSLNGQCQLKVKGDTCYCCDLYNCQSAEHPATYYEFVGVSSCQDVLHLYRLLWASAVLNVLGLFLGIVTAAVLGAFKDMVPLSQLAYGPSSPPQTLYNPAQQILAYAGFCQAPPAGAPCSSFPLPLQPSCTFTASPRTDLSLSEDVWLPSQSSSGCRLPPNAPPVSAPTCFLPGEKPPPYAP", "length": 329, "header": "tr|A0A287B0T4-1|A0A287B0T4_PIG Isoform 1 of Transmembrane protein 255B OS=Sus scrofa OX=9823 GN=TMEM255B PE=3 SV=1 CANONICAL=A0A287B0T4-1" }, "locus": { "chromosome": "11", "start_pos": 78837616, "end_pos": 78816922, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038343.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038343.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050029.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050029.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0T4", "url": "https://www.uniprot.org/uniprotkb/A0A287B0T4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100738464", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738464", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MK90-1", "protein_name": "Transmembrane protein 255B", "gene_name": "Tmem255b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPLPPPVPGPLALLDTTEGFARRKKISLWFVGSLLLVSTLILTIGLAATTRTENVTVGGYYPGIILGFGSFLGIIGIHLVENRRQMLVAAIVFLSFGVVAAFCCAIVDGVFAARHIEPRPLSAGRCQFYSSGAGYLYDVYQTEVTCYSLSGRCQLKVRSNTCYCCDLYACGSAEPSPAYYEFVGVRSCRDVVHLYRLLWASTVLNVLGLCLGIVTAAVLGAFKDMVPLSQLAYGPSPPPQILYNPAQQILAYTGLCPPSMSVPTCSSYPLPLQPSSAPPASADLFLPEDTESPSQCHSSHGHPHAPSPCTPAYFLPGEKPPPYVP", "length": 326 }, "evidence": [ { "id": "A0A287B0T4", "url": "https://omabrowser.org/oma/group/A0A287B0T4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A1D5PFG6-1", "protein_name": "Transmembrane protein 255B", "gene_name": "TMEM255B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMAPATAPAVAGPLALLDPTGQFAKRKKTSLWFTVSLLVVSIFILTIGLAATTRTENVTVGGYYPGIILGFGSFLGIVGIHLVENRRQMLVASIVFISFGVVAAFCCAIVDGVFAARHIEPRPLYNRRCQFYSSGVGFLYDAYQTEVTCYTLNTKCQLKVKSNTCYCCDLYNCENSEQSSSYYEFLGVSSCQDVVHLYRLLWSSTVLNIIGLFLGIITAAILGAFKDMVPMSHIAFSSAPPPQILYNPAQQILTYAGFCPSAATISAYPSYPLPLQPASNFPGTSSTDISLSEETQPPSQSSSSYGLPPNAPPLYAPTYFLPGEKPPPYAP", "length": 331 }, "evidence": [ { "id": "A0A287B0T4", "url": "https://omabrowser.org/oma/group/A0A287B0T4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5FW56-1", "protein_name": "Transmembrane protein 255B", "gene_name": "Tmem255b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGAEGRWREKGNDQRRGRKKRGGVEESGHRAAFLETAGTLKPNHRAGGASGHCPPSGGHFGNAAAPTARARPSGSAGHHRGLCQEEEDLSVVCGLSPAGVYSHPDHWPCCNHQDRECDCGRLLPRDYFAASIVFLSFGVVAAFCCAIVDSVFAARHIEPRPLSAGRCQFYSSGAGYLYDVYQTEVTCYSLNGRCQLKVRSNTCYCCDLYACGSTEPSPAYYEFVGVRSCQDVVHLYRLLWVSTVLNVLGLCLGIVTAAVLGAFKDMVPLSQLAYGPSPPPQILYNPAQQILAYTGLCPPSMGVPTCSSYPLPLQPSSAPPASASADLSLPEDTESPSQCQPSRGCSHAPSPCTPAYFLPGEKPPPYAP", "length": 369 }, "evidence": [ { "id": "A0A287B0T4", "url": "https://omabrowser.org/oma/group/A0A287B0T4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WV15-1", "protein_name": "Transmembrane protein 255B", "gene_name": "TMEM255B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPPVPGPLGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYPGIILGFGSFLGIIGINLVENRRQMLVAAIVFISFGVVAAFCCAIVDGVFAAQHIEPRPLTTGRCQFYSSGVGYLYDVYQTEVTCHSLDGKCQLKVRSNTCYCCDLYACGSAEPSPAYYEFIGVSGCQDVLHLYRLLWASAVLNVLGLFLGIITAAVLGAFKDMVPLSQLAYGPAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPPPYAP", "length": 326 }, "evidence": [ { "id": "A0A287B0T4", "url": "https://omabrowser.org/oma/group/A0A287B0T4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0T4", "url": "https://www.uniprot.org/uniprotkb/A0A287B0T4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B0V3-1", "uniprot_ac": "A0A287B0V3", "uniprot_id": "A0A287B0V3_PIG", "mass": { "chemical_mass": 13805.0, "monoisotopic_mass": 13805.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A287B0V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B0V3", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V3", "locus": {} } ], "crossref": [ { "id": "A0A287B0V3", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B0V3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000049531", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000049531", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "A0A287B0V3", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RGMIHPRIAVLTFSAVYTSSVSTSRLDTAQIATTRYTCTSTSAASAAAAAGPTTSREDALGAAPPSSSHSSTVAVAVSAGSPWSFTSTSRRWRAASASSRARVVLISPVYSPTRNALRAPPGAAAASCSSYDSHAL", "length": 136, "header": "tr|A0A287B0V3-1|A0A287B0V3_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A287B0V3-1" }, "isoforms": [ { "isoform_ac": "A0A287B0V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V3/entry#A0A287B0V3-1", "sequence": { "sequence": "RGMIHPRIAVLTFSAVYTSSVSTSRLDTAQIATTRYTCTSTSAASAAAAAGPTTSREDALGAAPPSSSHSSTVAVAVSAGSPWSFTSTSRRWRAASASSRARVVLISPVYSPTRNALRAPPGAAAASCSSYDSHAL", "length": 136, "header": "tr|A0A287B0V3-1|A0A287B0V3_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A287B0V3-1" }, "locus": { "chromosome": "2", "start_pos": 142532894, "end_pos": 142532259, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055785.2", "url": "https://www.ensembl.org/id/ENSSSCT00000055785.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049742.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049742.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Thr", "end_pos": 53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0V3", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B0V3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 136, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B0V3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B0V3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 53 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B0V5-1", "uniprot_ac": "A0A287B0V5", "uniprot_id": "A0A287B0V5_PIG", "mass": { "chemical_mass": 56318.0, "monoisotopic_mass": 56318.0 }, "refseq": {}, "gene_names": [ { "name": "ARMCX5", "type": "recommended", "evidence": [ { "id": "A0A287B0V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V5" } ] } ], "protein_names": [ { "name": "Armadillo repeat containing X-linked 5", "type": "synonym", "evidence": [ { "id": "A0A287B0V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B0V5", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARMCX5", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V5", "locus": { "chromosome": "X", "start_pos": 83769889, "end_pos": 83764771, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012518", "url": "https://www.ensembl.org/id/ENSSSCG00000012518" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012518", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012518", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NPKACRC", "url": "https://omabrowser.org/oma/group/NPKACRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR47081", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47081", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47081:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47081:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B0V5", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMTREVSKMEAKTKTRVVAETKSKPLVEPSVVSQTKSKTMPVSKISAVIEYEVKAGAASEPNIRSFARADDKDNTQSRSQRRREASMKFRAGDGAGIVIESSDDEENACSWFWTGEEPSVGSWFWPEEETPFQVYEPPPKIPEKPKPTPKPKPELTIKQKAAAWSRARYCVLVPIEGGEGSLPPEGNWTLVETLIETPLGIRPLTKIPPYNGPYFQTLAEIKKQVKYREKYGPNPKTCRCKSRVFSLEPKEFDKLVALLKLTRDPFIHQIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNVIEHPRALNKVDDNSGSSGQPKTGELYVNQVCKEIISSPLNSPVQLAGLKLLVQLSVKFEDHHMIINYIPDFLTLLNKGSVKTKFYVLKVFSRLSKNQANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKKKVKLFTKEEFTKSELISIFQEAKEFGQKLQDLAEHSDPEVRDKVIRLILKL", "length": 499, "header": "tr|A0A287B0V5-1|A0A287B0V5_PIG Isoform 1 of Armadillo repeat containing X-linked 5 OS=Sus scrofa OX=9823 GN=ARMCX5 PE=4 SV=2 CANONICAL=A0A287B0V5-1" }, "isoforms": [ { "isoform_ac": "A0A287B0V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V5/entry#A0A287B0V5-1", "sequence": { "sequence": "MAMTREVSKMEAKTKTRVVAETKSKPLVEPSVVSQTKSKTMPVSKISAVIEYEVKAGAASEPNIRSFARADDKDNTQSRSQRRREASMKFRAGDGAGIVIESSDDEENACSWFWTGEEPSVGSWFWPEEETPFQVYEPPPKIPEKPKPTPKPKPELTIKQKAAAWSRARYCVLVPIEGGEGSLPPEGNWTLVETLIETPLGIRPLTKIPPYNGPYFQTLAEIKKQVKYREKYGPNPKTCRCKSRVFSLEPKEFDKLVALLKLTRDPFIHQIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNVIEHPRALNKVDDNSGSSGQPKTGELYVNQVCKEIISSPLNSPVQLAGLKLLVQLSVKFEDHHMIINYIPDFLTLLNKGSVKTKFYVLKVFSRLSKNQANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKKKVKLFTKEEFTKSELISIFQEAKEFGQKLQDLAEHSDPEVRDKVIRLILKL", "length": 499, "header": "tr|A0A287B0V5-1|A0A287B0V5_PIG Isoform 1 of Armadillo repeat containing X-linked 5 OS=Sus scrofa OX=9823 GN=ARMCX5 PE=4 SV=2 CANONICAL=A0A287B0V5-1" }, "locus": { "chromosome": "X", "start_pos": 83769570, "end_pos": 83768074, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076698.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076698.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072926.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072926.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0V5", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A061HW88-1", "protein_name": "Armadillo repeat-containing X-linked protein 5", "gene_name": "Armcx5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIGSTTKAKGREESGASLKPGSKSLANAKEKAKSQTKKVVEAKPKEELGTQAEARDEAMARTQTVTHTEPETMTWKVKKKKDKTNTRVKDQTKTELRAEPGLVPHTKADDLPMSVVITVTKSEIRVDTGIETSIKYSSKASDKGSMKHISEIKKETLVRSGAGDKASIVINTTDEDEEYVCSWFWTGEEPSVGSWFWPKEETPLQVYQPPPKVEEEPEPTDNFDFTLKRKAAAWARGRFIVLVPVEEFEQSLPPEGNWTLVATLIETPLGIRPLTKIPPFEGPYFQTLAEIKNQIREREKYGPNPKTCRCKSRTFSLEPIEFDKLVALLKLTRDPFIHEIATMIMGISPAYPFTQDIVHDVGITVMIENFVNNPNAKNHSRTVNVSASADTSEEAKENEAHVDKVCRDILSCPLNCSVQVEELKLLASLSMKFENHHVIINYVRHFITLLSKGSVKLKFQILRVILYLSKNQANTRELISAEVLSSLVALFHKNESKANVLHIINIFENINFQFKKRAKLFTKEMFTKSELISIFQEAKQFDLKLQDLIDHSDPEVRDKIIRLILKL", "length": 567 }, "evidence": [ { "id": "A0A287B0V5", "url": "https://omabrowser.org/oma/group/A0A287B0V5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A548-1", "protein_name": "Armadillo repeat containing, X-linked 5", "gene_name": "Armcx5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIGSKTKKKAREESGPSPKPGTNSPANAKGKGKGQTNKGGKAEPKVEWGNQAEARDGAVARTQPVVPTEPKTVTWKVKKKKDKTNTRVTAQAKTELLAEPALVPHTKSDALPPSVLITVTKSEVKVDTGGEPSVKGSAKANDKHSIKHKSEIKKEVCVRSRAGDKASNVNTTDEDDEDYVCSWFWTGEEPSVGSWFWPKEENSLQAYQPPPKVEEEPEPPDTFDFALKKKAAAWLRGRFIVLVPIEEPQPSLPPEGNWTLVATLIETPLGIRPLTKIPPYGGPYFQTLADLKNQIREKEKYGPNPKTCRCKSRTFSLEPVEFDKLVALLKLTRDPFIHEIATMIMGISPAYPFTQDIVHDVGITVLIENFVNNPNAKKYPRNLNLNANPDAPEEVRETEAHVNKVCRDILSCPLNCSVQVEELKLLVSLSVKFDYHHVVIYYVRYFISLLNKGSVKIKFQILRVILCLSKNQANTRELISAEVMSSLVAHFHKNESKANILHIIEIFENINFQFKKRAKLFTKEMFTKSELISIFREAKEFDQKLQDLTDHSDPDVRDKVIRLILKL", "length": 567 }, "evidence": [ { "id": "A0A287B0V5", "url": "https://omabrowser.org/oma/group/A0A287B0V5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UZB0-1", "protein_name": "Armadillo repeat-containing X-linked protein 5", "gene_name": "Armcx5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIGSKTKRKAREESGASSKPGTNSPANAKGKAKNQTTKAVKAEPKEEWGNQAEARDEAVARTQPAISTEPKTVTWKVKKKKDKTNARVMAQAKTELPAGPALVPHTKSDALPTSVVITVTKSEVKIDTGIEASLKGAAKATDKRSIKQKPEIKKEVCVKSRAGDKAKEVCVKSSAGDKAKEVCVKSRAGDKAKEVCVKSRAGDKASIVINTTDEDEDYVCSWFWTGEEPSVGSWFWPKEENPLQVYQPPPKVEEEPEPPDTFDYALKKKAAAWLRGRFIVLVPIEEPQPSLPPDGNWTLVATLIETPLGIRPLTKIPPYGGPYFQTLADLKNQIREKEKYGPNPNTCRCKSRTFSLEPVDFDKLVALLKLTRDPFIHEIATMIMGISPAYPFTQDIVHDVGITVMIENFVNNPNAKKYPRTLNINANPDAPEEVKETEAHVNKVCRDILCCPLNCSVQVEELKLLVSLSVKFDYHHVVIYYVRYFISLLNKGSVKIKFQILRVLLCLSKNQANTRELISAEVMSSLVALFHKNESKANILHIIEIFENINFQFKKRAKLFTKEMFTKSELISIFREAKEFDQKLQDLTDHSDPDVRDKVIRLILKL", "length": 606 }, "evidence": [ { "id": "A0A287B0V5", "url": "https://omabrowser.org/oma/group/A0A287B0V5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6P1M9-1", "protein_name": "Armadillo repeat-containing X-linked protein 5", "gene_name": "ARMCX5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDSGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPTLTIKQKVIAWSRARYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPEVRDKVIRLILKL", "length": 558 }, "evidence": [ { "id": "A0A287B0V5", "url": "https://omabrowser.org/oma/group/A0A287B0V5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B0V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0V5" }, { "id": "PF04826", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Armadillo repeat-containing", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 468, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 }, { "start_pos": 426, "end_pos": 428 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B0X8-1", "uniprot_ac": "A0A287B0X8", "uniprot_id": "A0A287B0X8_PIG", "mass": { "chemical_mass": 92245.0, "monoisotopic_mass": 92245.0 }, "refseq": { "ac": "XP_005667978", "name": "HHIP-like protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667978" }, "gene_names": [ { "name": "HHIPL2", "type": "recommended", "evidence": [ { "id": "A0A287B0X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8" } ] }, { "name": "TAF1A", "type": "recommended", "evidence": [ { "id": "A0A287B0X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8" } ] }, { "name": "HHIPL2", "type": "synonym", "evidence": [ { "id": "XP_005667978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667978" }, { "id": "A0A287B0X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8" } ] } ], "protein_names": [ { "name": "HHIP like 2", "type": "synonym", "evidence": [ { "id": "A0A287B0X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8/entry#names_and_taxonomy" } ] }, { "name": "HHIP-like protein 2", "type": "synonym", "evidence": [ { "id": "XP_005667978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667978" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B0X8", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TAF1A", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8", "locus": { "chromosome": "10", "start_pos": 11340642, "end_pos": 11362432, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010833", "url": "https://www.ensembl.org/id/ENSSSCG00000010833" } ] } } ], "crossref": [ { "id": "A0A287B0X8", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B0X8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010832", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010832", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSSSCG00000010833", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010833", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100517774", "url": "https://www.ncbi.nlm.nih.gov/gene/100517774", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517774", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517774", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B0X8", "url": "https://www.orthodb.org/?gene=A0A287B0X8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19328:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19328:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07995", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07995", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005667978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667978", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B0X8", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S9I3", "url": "https://www.uniprot.org/uniprotkb/F1S9I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S9I3-1", "url": "https://www.uniprot.org/uniprotkb/F1S9I3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDHGCHRQHHTLGPAAGHPAAQQSGRASCQLLFEGPGGDRDTFQRFRKRQLPGPQGRGSETTSANPVRGGRRRRKETRAGAEGAPRRAGARPERAQRSRAPTMLAAPSRARSPQAPWLLSASRILCLCLAVVLGWAGLLQGHPQCLDYGPPFQPLLPLEFCSDYDNFGCCDQRKDRRIAARYWDIMEYFDLKGHELCGGYIKDILCQECSPYAAHLYDAENPRTPLRNLPGLCSDYCSAFHSNCHSAISLLTSDRRLQQSHQKDGARFCHLLNLPDQDYCFPNVLRSNHLTGKLGVVAEDPRGCLQLCLAEVANGLRNPVSMVHAGDGTHRLFVAEQVGVVWVFLPDGSRLEQPFLDLKSIVLSSPWIGDERGFLGLAFHPQFRRNRKFYIYYSCLGKKRAEKIRISEMKVSRADPNKADPKSERVILEIEEPASNHNGGQLLFGLDGYMYIFTGDGGQAGDPFGKFGNAQNKSSLLGKVLRIDVNGAGSGGQRYRVPRDNPFVSEPGAHPAIYAYGIRNMWRCAVDRGDPVTRKGRGRMFCGDVGQNRFEEIDIIVKGGNYGWRAKEGFECYDKTLCHNSSLDDILPIYAYGHAVGKSVTGGHVYRGCESPNLNGLYIFGDFMSGRLMALQEDRRTKKWKKRDICLSNTESCAFPGLISTYSKFIISFAEDEAGELYFLATSYPSAYAARGSIYKFVDPSRRAPPGKCTYKPVPVKIKSKRIPFRPLAKTVLDLLKEQAEEAARKSSNATVTSRPDRASSRKGPSKKPASPTSSRKPFPRPGAKKRVWSPGPQGRRKQSPKTPPGRGAQRQRAGRSLPLMLPSRWWVRG", "length": 830, "header": "tr|A0A287B0X8-1|A0A287B0X8_PIG Isoform 1 of HHIP like 2 OS=Sus scrofa OX=9823 GN=TAF1A PE=3 SV=2 CANONICAL=A0A287B0X8-1" }, "isoforms": [ { "isoform_ac": "A0A287B0X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8/entry#A0A287B0X8-1", "sequence": { "sequence": "MDHGCHRQHHTLGPAAGHPAAQQSGRASCQLLFEGPGGDRDTFQRFRKRQLPGPQGRGSETTSANPVRGGRRRRKETRAGAEGAPRRAGARPERAQRSRAPTMLAAPSRARSPQAPWLLSASRILCLCLAVVLGWAGLLQGHPQCLDYGPPFQPLLPLEFCSDYDNFGCCDQRKDRRIAARYWDIMEYFDLKGHELCGGYIKDILCQECSPYAAHLYDAENPRTPLRNLPGLCSDYCSAFHSNCHSAISLLTSDRRLQQSHQKDGARFCHLLNLPDQDYCFPNVLRSNHLTGKLGVVAEDPRGCLQLCLAEVANGLRNPVSMVHAGDGTHRLFVAEQVGVVWVFLPDGSRLEQPFLDLKSIVLSSPWIGDERGFLGLAFHPQFRRNRKFYIYYSCLGKKRAEKIRISEMKVSRADPNKADPKSERVILEIEEPASNHNGGQLLFGLDGYMYIFTGDGGQAGDPFGKFGNAQNKSSLLGKVLRIDVNGAGSGGQRYRVPRDNPFVSEPGAHPAIYAYGIRNMWRCAVDRGDPVTRKGRGRMFCGDVGQNRFEEIDIIVKGGNYGWRAKEGFECYDKTLCHNSSLDDILPIYAYGHAVGKSVTGGHVYRGCESPNLNGLYIFGDFMSGRLMALQEDRRTKKWKKRDICLSNTESCAFPGLISTYSKFIISFAEDEAGELYFLATSYPSAYAARGSIYKFVDPSRRAPPGKCTYKPVPVKIKSKRIPFRPLAKTVLDLLKEQAEEAARKSSNATVTSRPDRASSRKGPSKKPASPTSSRKPFPRPGAKKRVWSPGPQGRRKQSPKTPPGRGAQRQRAGRSLPLMLPSRWWVRG", "length": 830, "header": "tr|A0A287B0X8-1|A0A287B0X8_PIG Isoform 1 of HHIP like 2 OS=Sus scrofa OX=9823 GN=TAF1A PE=3 SV=2 CANONICAL=A0A287B0X8-1" }, "locus": { "chromosome": "10", "start_pos": 11335454, "end_pos": 11316175, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040888.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040888.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050053.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050053.2" } ] } }, { "isoform_ac": "F1S9I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8/entry#F1S9I3-1", "sequence": { "sequence": "MRTPPLSYITYWRCDLYLSCAHYIPSTYPSYNAPWLLSASRILCLCLAVVLGWAGLLQGHPQCLDYGPPFQPLLPLEFCSDYDNFGCCDQRKDRRIAARYWDIMEYFDLKGHELCGGYIKDILCQECSPYAAHLYDAENPRTPLRNLPGLCSDYCSAFHSNCHSAISLLTSDRRLQQSHQKDGARFCHLLNLPDQDYCFPNVLRSNHLTGKLGVVAEDPRGCLQLCLAEVANGLRNPVSMVHAGDGTHRLFVAEQVGVVWVFLPDGSRLEQPFLDLKSIVLSSPWIGDERGFLGLAFHPQFRRNRKFYIYYSCLGKKRAEKIRISEMKVSRADPNKADPKSERVILEIEEPASNHNGGQLLFGLDGYMYIFTGDGGQAGDPFGKFGNAQNKSSLLGKVLRIDVNGAGSGGQRYRVPRDNPFVSEPGAHPAIYAYGIRNMWRCAVDRGDPVTRKGRGRMFCGDVGQNRFEEIDIIVKGGNYGWRAKEGFECYDKTLCHNSSLDDILPIYAYGHAVGKSVTGGHVYRGCESPNLNGLYIFGDFMSGRLMALQEDRRTKKWKKRDICLSNTESCAFPGLISTYSKFIISFAEDEAGELYFLATSYPSAYAARGSIYKFVDPSRRAPPGKCTYKPVPVKIKSKRIPFRPLAKTVLDLLKEQAEEAARKSSNATVTSRPDRASSRKGPSKKPASPTSSRKPFPRPGAKKRVWSPGPQGRRKQSPKTPPGRGAQRQRAGRSLPLMLPSRWWVRG", "length": 748, "header": "tr|F1S9I3-1|A0A287B0X8_PIG Computationally mapped isoform of HHIP like 2 OS=Sus scrofa OX=9823 GN=TAF1A PE=3 SV=4 CANONICAL=A0A287B0X8-1" }, "locus": { "chromosome": "10", "start_pos": 11336308, "end_pos": 11316175, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011850.4", "url": "https://www.ensembl.org/id/ENSSSCT00000011850.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011547.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011547.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S9I3", "url": "https://www.uniprot.org/uniprotkb/F1S9I3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517774", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517774", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0X8", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 749, "end_pos": 751, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B0X8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 830, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B0X8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B0X8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B0X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8" }, { "id": "PF03024", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03024" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Folate receptor-like", "eco_id": "ECO_0000259", "start_pos": 159, "end_pos": 280, "start_aa": "Glu", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287B0X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0X8" }, { "id": "PF07995", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07995" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glucose/Sorbosone dehydrogenase", "eco_id": "ECO_0000259", "start_pos": 316, "end_pos": 639, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 472, "end_pos": 474 }, { "start_pos": 580, "end_pos": 582 }, { "start_pos": 749, "end_pos": 751 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B0Y2-1", "uniprot_ac": "A0A287B0Y2", "uniprot_id": "A0A287B0Y2_PIG", "mass": { "chemical_mass": 24192.0, "monoisotopic_mass": 24192.0 }, "refseq": { "ac": "XP_013837919", "name": "TPA-induced transmembrane protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013837919" }, "gene_names": [ { "name": "C13H3orf52", "type": "recommended", "evidence": [ { "id": "A0A287B0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y2" } ] }, { "name": "C13H3orf52", "type": "synonym", "evidence": [ { "id": "XP_013837919", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013837919" } ] }, { "name": "C3orf52", "type": "synonym", "evidence": [ { "id": "A0A287B0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y2" } ] } ], "protein_names": [ { "name": "Chromosome 13 C3orf52 homolog", "type": "synonym", "evidence": [ { "id": "A0A287B0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y2/entry#names_and_taxonomy" } ] }, { "name": "TPA-induced transmembrane protein", "type": "synonym", "evidence": [ { "id": "XP_013837919", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013837919" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "C13H3orf52", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y2", "locus": {} } ], "crossref": [ { "id": "A0A287B0Y2", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B0Y2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000033637", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033637", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100626261", "url": "https://www.ncbi.nlm.nih.gov/gene/100626261", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626261", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626261", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GFMKYMM", "url": "https://omabrowser.org/oma/group/GFMKYMM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287B0Y2", "url": "https://www.orthodb.org/?gene=A0A287B0Y2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14636", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14636", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14636:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14636:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_013837919", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013837919", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVU5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEARPPSPGDDLELSVLQGQPEEQTPLNGTVQSILSLTEEPCSVQADKESPWSSCNKNLIGKCKLWMVLTSVFLGFIIVIIIGLCLTGVTYVDEDENEILELSSNKTFLVMLKIPEACVTEEELPNLLTKRLTDVYSSSPALSRYFTSVEIMDFSGENATITYHLQFRVPSEDHSFMKYMMSEELVLGVLQQDLHDQNMSGCEALGLDPASLLLYE", "length": 217, "header": "tr|A0A287B0Y2-1|A0A287B0Y2_PIG Isoform 1 of Chromosome 13 C3orf52 homolog OS=Sus scrofa OX=9823 GN=C13H3orf52 PE=4 SV=1 CANONICAL=A0A287B0Y2-1" }, "isoforms": [ { "isoform_ac": "A0A287B0Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y2/entry#A0A287B0Y2-1", "sequence": { "sequence": "MEEARPPSPGDDLELSVLQGQPEEQTPLNGTVQSILSLTEEPCSVQADKESPWSSCNKNLIGKCKLWMVLTSVFLGFIIVIIIGLCLTGVTYVDEDENEILELSSNKTFLVMLKIPEACVTEEELPNLLTKRLTDVYSSSPALSRYFTSVEIMDFSGENATITYHLQFRVPSEDHSFMKYMMSEELVLGVLQQDLHDQNMSGCEALGLDPASLLLYE", "length": 217, "header": "tr|A0A287B0Y2-1|A0A287B0Y2_PIG Isoform 1 of Chromosome 13 C3orf52 homolog OS=Sus scrofa OX=9823 GN=C13H3orf52 PE=4 SV=1 CANONICAL=A0A287B0Y2-1" }, "locus": { "chromosome": "13", "start_pos": 147680022, "end_pos": 147649549, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061777.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061777.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049881.1", "url": "https://www.ensembl.org/id/ENSSSCP00000049881.1" } ] } }, { "isoform_ac": "A0A5G2QVU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y2/entry#A0A5G2QVU5-1", "sequence": { "sequence": "MEEARPPSPGDDLELSVLQGQPEEQTPLNGTVQSILSLTEEPCSVQADKESPWSSCNKNLIGKCKLWMVLTSVFLGFIIVIIIGLCLTGVTYVDEDENEILELSSNKTFLVMLKIPEACVTEEELPNLLTKREVRLNPEAVMGFE", "length": 145, "header": "tr|A0A5G2QVU5-1|A0A287B0Y2_PIG Computationally mapped isoform of Chromosome 13 C3orf52 homolog OS=Sus scrofa OX=9823 GN=C13H3orf52 PE=4 SV=1 CANONICAL=A0A287B0Y2-1" }, "locus": { "chromosome": "13", "start_pos": 147680022, "end_pos": 147647083, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070796.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070796.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069079.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069079.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVU5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVU5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626261", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626261", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XD72-1", "protein_name": "Chromosome 1 open reading frame, human C3orf52", "gene_name": "C1H3ORF52", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSWLRACYRDRGPRTETEAMKRQSSGGEHEVIELPEVNGEESTADHKKPLNPQVPATSKERDQWKSCRKIIFWKCKLWMVLTTIFVVLFLVILISLALYSNVYTDEDDYWYTDELLQNYHNFSGKFNLLCGLPHVFSEDIIKRITDVYSSSPALGRYFRSAKVDYFSNESSTVFYQLEFFVPPSTEGFMENVMNPDFIRNVLLQNIYDEEDTSNPGTSECTRLKLDPVSLTST", "length": 233 }, "evidence": [ { "id": "A0A287B0Y2", "url": "https://omabrowser.org/oma/group/A0A287B0Y2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1LVG2-1", "protein_name": "Similar to human chromosome 3 open reading frame 52", "gene_name": "C11h3orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGSRTPSSREELELSIVEGQQEELTPLNSLQIQPCSTQDPSPAQVDQERPWSSCNKSVVGKCKLWMAIVSIFLCFTIVVIISLCLVGVTYIDEDENEMPELSSNKTFFIVLKIPEECANEEELHHLLTKRLTDMYRQSPALNRFFTSADIMDFSVENATVTYHLQFGVPSEDDDFMKYMMSEELVLGIMRQSFHDKNLSTCENLGLDPESLLLYE", "length": 216 }, "evidence": [ { "id": "A0A287B0Y2", "url": "https://omabrowser.org/oma/group/A0A287B0Y2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5BVD1-1", "protein_name": "TPA-induced transmembrane protein", "gene_name": "TTMP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLAQPSQPVDELELSVLERQPEENTPLNGADKVFPSLDEEVPPAEANKESPWSSCNKNVVGRCKLWMIITSIFLGVITVIIIGLCLAAVTYVDEDENEILELSSNKTFFIMLKIPEECVAEEELPHLLTERLTDVYSTSPSLGRYFTSVEIVDFSGENATVTYDLQFGVPSDDENFMKYMMSEELVLGILLQDFRDQNIPGCESLGLDPTSLLLYE", "length": 217 }, "evidence": [ { "id": "A0A287B0Y2", "url": "https://omabrowser.org/oma/group/A0A287B0Y2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C5C9-1", "protein_name": "TPA-induced transmembrane protein homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEGSRSQSPREELELSMLDGPQEELTPLNNDLRIQPNSAEDPSPAQVGKESPWSPCNKSVVGKCKLWMVIVTIFLCFIIVIVISLCLVGVTYIDEDENEILELSSNKTFFITLKIPEECANEEGLHHLLTERLTDTYRQSPSLSRFFTSADILDFSVENATVTYHLQFGVPSEDDDFMKYMMSEELVLGIMRQSFHDKNISTCESLGLDPESLLLYE", "length": 218 }, "evidence": [ { "id": "A0A287B0Y2", "url": "https://omabrowser.org/oma/group/A0A287B0Y2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B0Y2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 217, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B0Y2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B0Y2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B0Y4-1", "uniprot_ac": "A0A287B0Y4", "uniprot_id": "A0A287B0Y4_PIG", "mass": { "chemical_mass": 20094.0, "monoisotopic_mass": 20094.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM276", "type": "recommended", "evidence": [ { "id": "A0A287B0Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y4" } ] } ], "protein_names": [ { "name": "Transmembrane protein 276", "type": "synonym", "evidence": [ { "id": "A0A287B0Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B0Y4", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMEM276", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y4", "locus": { "chromosome": "4", "start_pos": 334109, "end_pos": 332409, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000053131", "url": "https://www.ensembl.org/id/ENSSSCG00000053131" } ] } } ], "crossref": [ { "id": "A0A287B0Y4", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B0Y4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000027076", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027076", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "A0A287B0Y4", "url": "https://www.orthodb.org/?gene=A0A287B0Y4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A287B0Y4", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRPWSEWSASLSHLVLGTVSLHAAVSTAQASRGAAAGFLLQALAAATTLAPGLRTDEDCLAGAWVATVIGLPLLAFDFHWMNGDCSSANLLLGGGMVLAVAGDHLGAEGRSVAGQAVVLVVAVTILIVAVFTTNTYGMWGGVMLGAAGLLSRLEEDRLLLLPKEDLCRWALAAGSWTYHQALRAQRLQWE", "length": 192, "header": "tr|A0A287B0Y4-1|A0A287B0Y4_PIG Isoform 1 of Transmembrane protein 276 OS=Sus scrofa OX=9823 GN=TMEM276 PE=4 SV=1 CANONICAL=A0A287B0Y4-1" }, "isoforms": [ { "isoform_ac": "A0A287B0Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y4/entry#A0A287B0Y4-1", "sequence": { "sequence": "MASRPWSEWSASLSHLVLGTVSLHAAVSTAQASRGAAAGFLLQALAAATTLAPGLRTDEDCLAGAWVATVIGLPLLAFDFHWMNGDCSSANLLLGGGMVLAVAGDHLGAEGRSVAGQAVVLVVAVTILIVAVFTTNTYGMWGGVMLGAAGLLSRLEEDRLLLLPKEDLCRWALAAGSWTYHQALRAQRLQWE", "length": 192, "header": "tr|A0A287B0Y4-1|A0A287B0Y4_PIG Isoform 1 of Transmembrane protein 276 OS=Sus scrofa OX=9823 GN=TMEM276 PE=4 SV=1 CANONICAL=A0A287B0Y4-1" }, "locus": { "chromosome": "4", "start_pos": 333819, "end_pos": 333048, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040502.2", "url": "https://www.ensembl.org/id/ENSSSCT00000040502.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057776.1", "url": "https://www.ensembl.org/id/ENSSSCP00000057776.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0Y4", "url": "https://www.uniprot.org/uniprotkb/A0A287B0Y4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B0Y4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 192, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B0Y4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B0Y4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B132-1", "uniprot_ac": "A0A287B132", "uniprot_id": "A0A287B132_PIG", "mass": { "chemical_mass": 34125.0, "monoisotopic_mass": 34125.0 }, "refseq": {}, "gene_names": [ { "name": "LOC102158035", "type": "recommended", "evidence": [ { "id": "A0A287B132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B132" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A287B132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B132/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B132", "url": "https://www.uniprot.org/uniprotkb/A0A287B132" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC102158035", "url": "https://www.uniprot.org/uniprotkb/A0A287B132", "locus": {} } ], "crossref": [ { "id": "A0A287B132", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B132", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000022512", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022512", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSSSCG00000033721", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033721", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04983", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04983", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07688", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07688", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19339:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19339:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19367", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19367", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19367:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19367:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B132", "url": "https://www.uniprot.org/uniprotkb/A0A287B132", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B132-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B132-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BF83", "url": "https://www.uniprot.org/uniprotkb/A0A287BF83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BF83-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BF83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LGH7", "url": "https://www.uniprot.org/uniprotkb/I3LGH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LGH7-1", "url": "https://www.uniprot.org/uniprotkb/I3LGH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCKHTHLSGRVSMWLNCFQEKSAERSLLFPHSSDMKPTLISVLVMIFTLCGTRAQTVTQPEDHISVFERSPVQVKCNYSYSGSPVLFWYVQYPKQHLQLLLKHISRESIRGFTAHLDKKEASFHLKKPSAQEEDSAIYYCALSDTVTDKLTFGDGTSLTVKPNIKNPDPAVYQLKGPKSNNISVCLYTDFQMNTTKDSEPAVFSLSRTVFNSNTTVLDMGALGSKSNGLVAWSKSTDFECQSTFQQEFYPNSGISCDAKLVEKSFETDMNLNLQNLSVMGFRIILLKMVGFNLLMTLRLWSS", "length": 303, "header": "tr|A0A287B132-1|A0A287B132_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN=LOC102158035 PE=4 SV=3 CANONICAL=A0A287B132-1" }, "isoforms": [ { "isoform_ac": "A0A287B132-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B132/entry#A0A287B132-1", "sequence": { "sequence": "MSCKHTHLSGRVSMWLNCFQEKSAERSLLFPHSSDMKPTLISVLVMIFTLCGTRAQTVTQPEDHISVFERSPVQVKCNYSYSGSPVLFWYVQYPKQHLQLLLKHISRESIRGFTAHLDKKEASFHLKKPSAQEEDSAIYYCALSDTVTDKLTFGDGTSLTVKPNIKNPDPAVYQLKGPKSNNISVCLYTDFQMNTTKDSEPAVFSLSRTVFNSNTTVLDMGALGSKSNGLVAWSKSTDFECQSTFQQEFYPNSGISCDAKLVEKSFETDMNLNLQNLSVMGFRIILLKMVGFNLLMTLRLWSS", "length": 303, "header": "tr|A0A287B132-1|A0A287B132_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN=LOC102158035 PE=4 SV=3 CANONICAL=A0A287B132-1" }, "locus": { "chromosome": "7", "start_pos": 77056115, "end_pos": 76471218, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047337.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047337.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050109.3", "url": "https://www.ensembl.org/id/ENSSSCP00000050109.3" } ] } }, { "isoform_ac": "A0A287BF83-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B132/entry#A0A287BF83-1", "sequence": { "sequence": "MPDSAHIFHPQDLCLKEGSCQRLFGQKRESQKNATVVCCPRLVFEGKLRGRTELPDVTVATSGAAYGKKLLVQPDIKNPDPAVYQLKGPKSNNISVCLYTDFQMNTTKDSEPAVFSLSRTVFNSNTTVLDMGALGSKSNGLVAWSKSTDFECQSTFQQEFYPNSGISCDAKLVEKSFETDMNLNLQNLSVMGFRIILLKMVGFNLLMTLRLWSS", "length": 214, "header": "tr|A0A287BF83-1|A0A287BF83_PIG Computationally mapped isoform of T-cell receptor alpha chain constant domain-containing protein OS=Sus scrofa OX=9823 GN=LOC102158035 PE=4 SV=2 CANONICAL=A0A287B132-1" }, "locus": { "chromosome": "7", "start_pos": 76546645, "end_pos": 76471218, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037560.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037560.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054982.2", "url": "https://www.ensembl.org/id/ENSSSCP00000054982.2" } ] } }, { "isoform_ac": "I3LGH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B132/entry#I3LGH7-1", "sequence": { "sequence": "MKRLVGPVLGLLLAQVCCVRGVDVKQSPPALSLQEGASSTLWCNFSTTVNNVQWYRQYRNGSLVHLFFISSGTKWNGRLNATTVTKERRSSLYISSAQITDSATYFCAGESAQKLVFGRGTTLKVNLNIKNPDPAVYQLKGPKSNNISVCLYTDFQMNTTKDSEPAVFSLSRTVFNSNTTVLDMGALGSKSNGLVAWSKSTDFECQSTFQQEFYPNSGISCDAKLVEKSFETDMNLNLQNLSVMGFRIILLKMVGFNLLMTLRLWSS", "length": 267, "header": "tr|I3LGH7-1|A0A287B132_PIG Computationally mapped isoform of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN=LOC102158035 PE=4 SV=3 CANONICAL=A0A287B132-1" }, "locus": { "chromosome": "7", "start_pos": 76996129, "end_pos": 76471218, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026772.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026772.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023171.3", "url": "https://www.ensembl.org/id/ENSSSCP00000023171.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LGH7", "url": "https://www.uniprot.org/uniprotkb/I3LGH7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A287B132", "url": "https://www.uniprot.org/uniprotkb/A0A287B132" } ], "pmid": "" }, { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A287B132", "url": "https://www.uniprot.org/uniprotkb/A0A287B132" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A287B132", "url": "https://www.uniprot.org/uniprotkb/A0A287B132" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B132-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 303, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B132-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B132" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B132" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 152, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 182, "end_pos": 184 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B138-1", "uniprot_ac": "A0A287B138", "uniprot_id": "A0A287B138_PIG", "mass": { "chemical_mass": 101361.0, "monoisotopic_mass": 101361.0 }, "refseq": { "ac": "XP_020935446", "name": "MORC family CW-type zinc finger protein 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935446" }, "gene_names": [ { "name": "MORC4", "type": "recommended", "evidence": [ { "id": "A0A287B138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B138" } ] }, { "name": "MORC4", "type": "synonym", "evidence": [ { "id": "XP_020935446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935446" } ] } ], "protein_names": [ { "name": "MORC family CW-type zinc finger 4", "type": "synonym", "evidence": [ { "id": "A0A287B138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B138/entry#names_and_taxonomy" } ] }, { "name": "MORC family CW-type zinc finger protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020935446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935446" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B138", "url": "https://www.uniprot.org/uniprotkb/A0A287B138" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MORC4", "url": "https://www.uniprot.org/uniprotkb/A0A287B138", "locus": { "chromosome": "X", "start_pos": 87369319, "end_pos": 87427253, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036091", "url": "https://www.ensembl.org/id/ENSSSCG00000036091" } ] } } ], "crossref": [ { "id": "ENSSSCG00000036091", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036091", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100627548", "url": "https://www.ncbi.nlm.nih.gov/gene/100627548", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YKWIVGE", "url": "https://omabrowser.org/oma/group/YKWIVGE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23336:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23336:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07496", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07496", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13589", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13589", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17942", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17942", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020935446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935446", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B138", "url": "https://www.uniprot.org/uniprotkb/A0A287B138", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B138-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B138-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLYRGAPAGPGAPGSALARPGGGPQAFGIRLSTMSPRYLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVFIDVEEVKNKSCLTFTDDGCGMTPHKLHRMLSFGFTDKVIKKSQCPIGVFGNGFKSGSMRLGKDALVFTKNGGTLTVGLLSQTYLECVQAQAVIVPIVPFNQQNKKMIITEDSLPSLEAILNYSIFNSENDLLSQFDAIPGKKGTRVLIWNIRRNKDGKSELDFDTDQYDILVSDFGTEEKETGGASSELPETEYSLRAFCGILYMKPRMKIFLRQKKVTTQMIAKSLANVGYDIYKPTFTNKQVKITFGFSCKNNNQFGVMMYHNNRLIKSFEKVGCQVKPTQGEGVGVIGVIECNFLKPAYNKQDFEYTKEYRLTINALAQKLNAFWKEKTSQENFETSAIVRPIPKIPDQTWVQCDECLKWRKLPGKVDPSTLPARWFCYYNSHPKYRRCSVPEEQELIDEDLYLSKAKKQDQTIEKKKVPLENESHQVFTNPVKIPSIQDMEDLNNKTAGYEGIDSPSQLSSVGEESRTPSLQLKPLDSSVFQFSSKYKWILGEEPVEKRRKLQNEMTTPPLDYSMPGPYRRVEAAVAYPEGENSHDKSSSERSTPPYLSPEYPEAVKSTSQSREVSVLYAGAQDPHQGSLLPEELEDQMPRLVAEESNRGSTHINKEEVSKGPFVAVVGVAKGVRDSGAPIQLIPFNREELAERRKAVESWNPPAPYSAVASAATPAAAAGEKGKGCEESGGRNTPKMKNQRELEELKRTTEKLERVLAERNMFQQKVEELEQERNHWHSEFKKVQHELVTYSTQETEGLYWSKKHMGYRQAEFQILKAELERTKEEKQELKEKLKETETHLEVLQKAQGFGKAYTAAYPRQLSPYFCPPSLGAS", "length": 901, "header": "tr|A0A287B138-1|A0A287B138_PIG Isoform 1 of MORC family CW-type zinc finger 4 OS=Sus scrofa OX=9823 GN=MORC4 PE=4 SV=1 CANONICAL=A0A287B138-1" }, "isoforms": [ { "isoform_ac": "A0A287B138-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B138/entry#A0A287B138-1", "sequence": { "sequence": "MLLYRGAPAGPGAPGSALARPGGGPQAFGIRLSTMSPRYLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVFIDVEEVKNKSCLTFTDDGCGMTPHKLHRMLSFGFTDKVIKKSQCPIGVFGNGFKSGSMRLGKDALVFTKNGGTLTVGLLSQTYLECVQAQAVIVPIVPFNQQNKKMIITEDSLPSLEAILNYSIFNSENDLLSQFDAIPGKKGTRVLIWNIRRNKDGKSELDFDTDQYDILVSDFGTEEKETGGASSELPETEYSLRAFCGILYMKPRMKIFLRQKKVTTQMIAKSLANVGYDIYKPTFTNKQVKITFGFSCKNNNQFGVMMYHNNRLIKSFEKVGCQVKPTQGEGVGVIGVIECNFLKPAYNKQDFEYTKEYRLTINALAQKLNAFWKEKTSQENFETSAIVRPIPKIPDQTWVQCDECLKWRKLPGKVDPSTLPARWFCYYNSHPKYRRCSVPEEQELIDEDLYLSKAKKQDQTIEKKKVPLENESHQVFTNPVKIPSIQDMEDLNNKTAGYEGIDSPSQLSSVGEESRTPSLQLKPLDSSVFQFSSKYKWILGEEPVEKRRKLQNEMTTPPLDYSMPGPYRRVEAAVAYPEGENSHDKSSSERSTPPYLSPEYPEAVKSTSQSREVSVLYAGAQDPHQGSLLPEELEDQMPRLVAEESNRGSTHINKEEVSKGPFVAVVGVAKGVRDSGAPIQLIPFNREELAERRKAVESWNPPAPYSAVASAATPAAAAGEKGKGCEESGGRNTPKMKNQRELEELKRTTEKLERVLAERNMFQQKVEELEQERNHWHSEFKKVQHELVTYSTQETEGLYWSKKHMGYRQAEFQILKAELERTKEEKQELKEKLKETETHLEVLQKAQGFGKAYTAAYPRQLSPYFCPPSLGAS", "length": 901, "header": "tr|A0A287B138-1|A0A287B138_PIG Isoform 1 of MORC family CW-type zinc finger 4 OS=Sus scrofa OX=9823 GN=MORC4 PE=4 SV=1 CANONICAL=A0A287B138-1" }, "locus": { "chromosome": "X", "start_pos": 87427010, "end_pos": 87370165, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054718.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054718.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050140.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050140.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 741, "start_aa": "Thr", "end_pos": 741, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr741", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B138", "url": "https://www.uniprot.org/uniprotkb/A0A287B138" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LBQ1-1", "protein_name": "MORC family CW-type zinc finger 4", "gene_name": "Morc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLYRGAPAAPGTPRGGLARAGSVPQAFRIRLSTISPRYLQSNSCSHTRPFSAIAELLDNAVDPDVCARTVFIDVEEVKNKPCLTFTDDGCGMTAHKLYRMLSFGFTDKVIKKSQCPIGVFGNGFKSGSMRLGKDVLVFTKNGSTLAVGLLSQTYLECIQAQAVIVPIVPFSQQNKKMIVTEDSLPSLEAILNYSIFNDERDLMSQFDAIPGKKGTRVLIWNIRRNKDGKAELDFDSDQYDILVSDFAAEEKMVDGVASELPETEYSLRAFCSILYMKPRMKIFLRQKKVTPQMIAKSLTNVEYDTYKPTSTNKQVRITFGFSCKYRNQFGVMMYHNNRLIKAFEKAGCQLKPTCGEGVGVIGVIECNFLKPAYNKQEFEYTKEYRLTINALAQKLNAYWKEKISQENFETSPISRGIPDQTWVQCDECLKWRKLPGKVDPSTLPARWFCYYNPHPKYKRCSVPEEQERIDEDLHRSKAKQQVEIVEKKQKPVESDKYQVFSNPPKIPTPQNMTQLNDKTIGYERINSPRLLPSVGEESRSPPRLKSLDSSAFQISRKYKLILGEEPAEKRRKIQTDTTLSPIDYSMSSYYRRVEAATAYPEGDNSPDKSSSERSTPPHLIPEYPESNKRAEQNREAPALCPGSQDQDQGFLLPEELEDQMPKLVAEESNRSSENIDKDMNKGPFVAVVGVAKGVADSGAPIQLVPFNREEFVGKRKRAESWKRANPYSSAAPAATAGNGKGCQESRSRNMAKTKNRKQLEELKRTTEKLERVLAERNLFQQKVEELEQEKNHWHSEYKKAQHELVTYSTQETEGLYWSKKHMGYRQAEFQILKAELERTKEEKQELKEKLKETQSHLEVLQKAQVSFRSPEGDDLERALARLTRLRVHVSYLLTSVLPHLELREIGFDSEQVDGILYTVLEANHILD", "length": 928 }, "evidence": [ { "id": "A0A287B138", "url": "https://omabrowser.org/oma/group/A0A287B138/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BMD7-1", "protein_name": "MORC family CW-type zinc finger protein 4", "gene_name": "Morc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLYRGAPAGPGTPGGGLARAGSVPQAFRIRLSTMSPRYLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVFIDVEEVKKKPCLTFTDDGCGMTPHKLHRMLSFGFTDKVIKKSQRPIGVFGNGFKSGSMRLGKDALVFTKNGNTLAVGLLSQTYLECIQAQAVIVPIVPFSQQNKKMIVTEDSLPSLEAILNYSIFNCEKDLLSQFDAIPGKKGTRVLIWNIRRNKDGKSELDFDTDQYDILVSDFDAEEKEIGGVTSELPETEYSLRAFCSILYMKPRMKIFLRQKKVTTQMIAKSLANVEYDIYKPTSTNKQVRITFGFSCKYHNQFGVMMYHNNRLIKAFEKAGCQLKPTCGEGVGVIGVIECNFLKPAYNKQDFEYTKEYRLTINALARKLNAYWKEKISQENFEPLPTSRRIPDQTWVQCDECLKWRRLPGMVDPSTLPARWFCYYNPHPKFKRCSVPEEQERIDEDLHRSKAKQQVEAAEKKQKPMESDKYQVFSNPPKTPPLQDMAELNDKTIGYEQINSPSLLPSVREESRSPPRLKSLDSSAFQISRKYKLILGEEPVEKRRKIQTEMPLSPIDYSMSGFYRRVEAATAYPEGENSPDKCSSERSTPPHLIPEYPESNKHTEENREAPALCPGSQDQDQGFLLPEELEDQMPKLVAEESNRSSENIDKDMNKGPFVAVVGVAKGVADSGAPIQLVPFNREEFVGKRKRAESWKRANPYSSAAPAATAGKGKDCQDSRSRNMPKIKTPKESEELKRTTEKLERVLAERNLFQQKVEELEQEKNHWHSEYKKAQHELVTYSTQETEGIYWSKKHMGYRQAEFQILKAELERTKEEKQELKEKLKETESHLEVLQKAQVSFRNPEGDDLERALARLTRLRVHVSYLLTSVLPHLELREIGYDSEQVDGILYTVLEANHILD", "length": 928 }, "evidence": [ { "id": "A0A287B138", "url": "https://omabrowser.org/oma/group/A0A287B138/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TE76-1", "protein_name": "MORC family CW-type zinc finger protein 4", "gene_name": "MORC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLYRGAPAGPGAPGCGLARPGGGPQAFGIRLSTMSPRYLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVFIDVEEVKNKSCLTFTDDGCGMTPHKLHRMLSFGFTDKVIKKSQCPIGVFGNGFKSGSMRLGKDALVFTKNGGTLTVGLLSQTYLECVQAQAVIVPIVPFNQQNKKMIITEDSLPSLEAILNYSIFNRENDLLAQFDAIPGKKGTRVLIWNIRRNKNGKSELDFDTDQYDILVSDFDTEEKMTGGVTSELPETEYSLRAFCGILYMKPRMKIFLRQKKVTTQMIAKSLANVEYDTYKPTFTNKQVRITFGFSCKNSNQFGIMMYHNNRLIKSFEKVGCQVKPTRGEGVGVIGVIECNFLKPAYNKQDFEYTKEYRLTINALAQKLNAYWKEKTSQDNFETSTVARPIPKVPDQTWVQCDECLKWRKLPGKIDPSMLPARWFCYYNSHPKYRRCSVPEEQELTDEDLCLSKAKKQEQTVEEKKKMPMENENHQVFSNPPKILTVQEMAGLNNKTIGYEGIHSPSVLPSGGEESRSPSLQLKPLDSSVLQFSSKYKWILGEEPVEKRRRLQNEMTTPSLDYSMPAPYRRVEAPVAYPEGENSHDKSSSERSTPPYLFPEYPEASKNTGQNREVSILYPGAKDQRQGSLLPEELEDQMPRLVAEESNRGSTTINKEEVNKGPFVAVVGVAKGVRDSGAPIQLIPFNREELAERRKAVESWNPVPYSVASAAIPAAAIGEKARGYEESEGHNTPKLKNQRELEELKRTTEKLERVLAERNLFQQKVEELEQERNHWQSEFKKVQHELVIYSTQEAEGLYWSKKHMGYRQAEFQILKAELERTKEEKQELKEKLKETETHLEMLQKAQVSYRTPEGDDLERALAKLTRLRIHVSYLLTSVLPHLELREIGYDSEQVDGILYTVLEANHILD", "length": 937 }, "evidence": [ { "id": "A0A287B138", "url": "https://omabrowser.org/oma/group/A0A287B138/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A287B138", "url": "https://www.uniprot.org/uniprotkb/A0A287B138" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A287B138", "url": "https://www.uniprot.org/uniprotkb/A0A287B138" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A287B138", "url": "https://www.uniprot.org/uniprotkb/A0A287B138" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A287B138", "url": "https://www.uniprot.org/uniprotkb/A0A287B138" } ], "pmid": "" }, { "name": "histone H3K4me3 reader activity", "id": "GO:0140002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140002", "evidence": [ { "database": "UniProtKB", "id": "A0A287B138", "url": "https://www.uniprot.org/uniprotkb/A0A287B138" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B138" }, { "id": "PS51050", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51050" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CW-type", "eco_id": "ECO_0000259", "start_pos": 420, "end_pos": 472, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 741 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 498, "end_pos": 500 }, { "start_pos": 521, "end_pos": 523 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B140-1", "uniprot_ac": "A0A287B140", "uniprot_id": "A0A287B140_PIG", "mass": { "chemical_mass": 72828.0, "monoisotopic_mass": 72828.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF189", "type": "recommended", "evidence": [ { "id": "A0A287B140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ] } ], "protein_names": [ { "name": "Zinc finger protein 189", "type": "synonym", "evidence": [ { "id": "A0A287B140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B140/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A287BGQ5", "url": "https://www.uniprot.org/uniprotkb/A0A287BGQ5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF189", "url": "https://www.uniprot.org/uniprotkb/A0A287B140", "locus": { "chromosome": "1", "start_pos": 243118344, "end_pos": 243106974, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034239", "url": "https://www.ensembl.org/id/ENSSSCG00000034239" } ] } } ], "crossref": [ { "id": "A0A287B140", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B140", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034239", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034239", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FHEREKP", "url": "https://omabrowser.org/oma/group/FHEREKP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24377", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B140-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B140-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BGQ5", "url": "https://www.uniprot.org/uniprotkb/A0A287BGQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BGQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BGQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPSPPTEPKGLLTFEDVAVFFTQEEWDYLDPAQRSLYKDVMMENYGNLVSLDVLNRDKDEAPTVKQEIEEIEEEVEPQSVIVTRIKSEIDQDPIGRETFELVGRLDKQRGIFLWEIPRESLTQEQRMFRGNTNIIRKRPNSEEKCHKCEECGKGFVRKAHFIQHQRVHTGEKPFQCNECGKSFSRSSFVIEHQRIHTGERPYECNYCGKTFSVSSTLIRHQRIHTGERPYQCNQCKQSFSQRRSLVKHQRIHTGEKPHKCSDCGKAFSWKSHLIEHQRTHTGEKPYHCTKCKKSFSRNSLLVEHQRIHTGERPHKCGECGKAFRLSTYLIQHQKIHTGEKPFLCIECKSFSRSSFLIEHQRIHTGERPYQCKECGKSFSQLCNLTRHQRIHTGDKPHKCEECGKAFSRSSGLIQHQRIHTREKTYSYNEPNESFDPNCSLVIQQEVYPKEKSYKCDECGKTFSVSAHLVQHQRIHTGEKPYLCTVCGKSFSRSSFLIEHQRIHTGERPYLCRQCGKSFSQLCNLIRHQGVHTGNKPHKCDECGKAFSRNSGLIQHQRIHTGEKPYKCEKCDKSFSQQRSLVNHQKIHAEVKIQETHECDACGEAFNCRISLIQHQKLHTTWMQ", "length": 625, "header": "tr|A0A287B140-1|A0A287B140_PIG Isoform 1 of Zinc finger protein 189 OS=Sus scrofa OX=9823 GN=ZNF189 PE=3 SV=1 CANONICAL=A0A287B140-1" }, "isoforms": [ { "isoform_ac": "A0A287B140-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B140/entry#A0A287B140-1", "sequence": { "sequence": "MASPSPPTEPKGLLTFEDVAVFFTQEEWDYLDPAQRSLYKDVMMENYGNLVSLDVLNRDKDEAPTVKQEIEEIEEEVEPQSVIVTRIKSEIDQDPIGRETFELVGRLDKQRGIFLWEIPRESLTQEQRMFRGNTNIIRKRPNSEEKCHKCEECGKGFVRKAHFIQHQRVHTGEKPFQCNECGKSFSRSSFVIEHQRIHTGERPYECNYCGKTFSVSSTLIRHQRIHTGERPYQCNQCKQSFSQRRSLVKHQRIHTGEKPHKCSDCGKAFSWKSHLIEHQRTHTGEKPYHCTKCKKSFSRNSLLVEHQRIHTGERPHKCGECGKAFRLSTYLIQHQKIHTGEKPFLCIECKSFSRSSFLIEHQRIHTGERPYQCKECGKSFSQLCNLTRHQRIHTGDKPHKCEECGKAFSRSSGLIQHQRIHTREKTYSYNEPNESFDPNCSLVIQQEVYPKEKSYKCDECGKTFSVSAHLVQHQRIHTGEKPYLCTVCGKSFSRSSFLIEHQRIHTGERPYLCRQCGKSFSQLCNLIRHQGVHTGNKPHKCDECGKAFSRNSGLIQHQRIHTGEKPYKCEKCDKSFSQQRSLVNHQKIHAEVKIQETHECDACGEAFNCRISLIQHQKLHTTWMQ", "length": 625, "header": "tr|A0A287B140-1|A0A287B140_PIG Isoform 1 of Zinc finger protein 189 OS=Sus scrofa OX=9823 GN=ZNF189 PE=3 SV=1 CANONICAL=A0A287B140-1" }, "locus": { "chromosome": "1", "start_pos": 243116879, "end_pos": 243107335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039074.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039074.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049942.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049942.2" } ] } }, { "isoform_ac": "A0A287BGQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B140/entry#A0A287BGQ5-1", "sequence": { "sequence": "MASPSPPTEPKEEWDYLDPAQRSLYKDVMMENYGNLVSLDVLNRDKDEAPTVKQEIEEIEEEVEPQSVIVTRIKSEIDQDPIGRETFELVGRLDKQRGIFLWEIPRESLTQEQRMFRGNTNIIRKRPNSEEKCHKCEECGKGFVRKAHFIQHQRVHTGEKPFQCNECGKSFSRSSFVIEHQRIHTGERPYECNYCGKTFSVSSTLIRHQRIHTGERPYQCNQCKQSFSQRRSLVKHQRIHTGEKPHKCSDCGKAFSWKSHLIEHQRTHTGEKPYHCTKCKKSFSRNSLLVEHQRIHTGERPHKCGECGKAFRLSTYLIQHQKIHTGEKPFLCIECGKASVGAHSLLNIRGSIQVKDLISAKSVGKASVNFATLLVIREFTRGTNHINVRNVEKPLVEAQVLFSIRESTPEKRLIHTMNLTKVLIQIAVLLYSRKSTLRKNLINVMNVGKLLVSVLILYSIRESTLVKSPTYVLYVGKASVGVHFLLNTRESTLVRDPICADSVAKVLVSFVILFDIRVFTQVINPINVMNVGRPLAGTQALFSIREYTQEKNLISVRSATKVLVNSAALSTIRRSMPR", "length": 578, "header": "tr|A0A287BGQ5-1|A0A287BGQ5_PIG Computationally mapped isoform of Zinc finger protein 189 OS=Sus scrofa OX=9823 GN=ZNF189 PE=3 SV=1 CANONICAL=A0A287B140-1" }, "locus": { "chromosome": "1", "start_pos": 243116778, "end_pos": 243107335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049810.2", "url": "https://www.ensembl.org/id/ENSSSCT00000049810.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055235.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055235.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ], "pmid": "" }, { "name": "positive regulation of biosynthetic process", "id": "GO:0009891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009891", "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A287B140", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B140-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 625, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B140-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B140" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 148, "end_pos": 175, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287B140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B140" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 89, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 385, "end_pos": 387 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 439, "end_pos": 441 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B153-1", "uniprot_ac": "A0A287B153", "uniprot_id": "A0A287B153_PIG", "mass": { "chemical_mass": 20435.0, "monoisotopic_mass": 20435.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Large ribosomal subunit protein uL22", "type": "recommended", "evidence": [ { "id": "A0A287B153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B153/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L17", "type": "synonym", "evidence": [ { "id": "A0A287B153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B153/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B153", "url": "https://www.uniprot.org/uniprotkb/A0A287B153" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A287B153", "locus": {} } ], "crossref": [ { "id": "A0A287B153", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B153", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000018018", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000018018", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11593", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11593", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11593:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11593:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B153", "url": "https://www.uniprot.org/uniprotkb/A0A287B153", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B153-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B153-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFCYLLDPENPTKSCNQEVQGVSVVAQMSLQKQCVPFCHYSGGGWTQGWWPKKSAEFLLHMLENAESNAKLKGLDVYSLVIEHIQVNKAPKIQRRTYRACGQINPYMSSPYATEMILPEKEQVVPKPEEVVAQKKKISQNKLKKQKFPVLAQWLTNPTSIPEDRCSILGLAQWSEDLALP", "length": 180, "header": "tr|A0A287B153-1|A0A287B153_PIG Isoform 1 of Large ribosomal subunit protein uL22 OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A287B153-1" }, "isoforms": [ { "isoform_ac": "A0A287B153-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B153/entry#A0A287B153-1", "sequence": { "sequence": "MFCYLLDPENPTKSCNQEVQGVSVVAQMSLQKQCVPFCHYSGGGWTQGWWPKKSAEFLLHMLENAESNAKLKGLDVYSLVIEHIQVNKAPKIQRRTYRACGQINPYMSSPYATEMILPEKEQVVPKPEEVVAQKKKISQNKLKKQKFPVLAQWLTNPTSIPEDRCSILGLAQWSEDLALP", "length": 180, "header": "tr|A0A287B153-1|A0A287B153_PIG Isoform 1 of Large ribosomal subunit protein uL22 OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A287B153-1" }, "locus": { "chromosome": "6", "start_pos": 17794226, "end_pos": 17792557, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049721.2", "url": "https://www.ensembl.org/id/ENSSSCT00000049721.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050155.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050155.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B153", "url": "https://www.uniprot.org/uniprotkb/A0A287B153" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A287B153", "url": "https://www.uniprot.org/uniprotkb/A0A287B153" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A287B153", "url": "https://www.uniprot.org/uniprotkb/A0A287B153" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A287B153", "url": "https://www.uniprot.org/uniprotkb/A0A287B153" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B153-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 180, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B153-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B153" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1D0-1", "uniprot_ac": "A0A287B1D0", "uniprot_id": "A0A287B1D0_PIG", "mass": { "chemical_mass": 26780.0, "monoisotopic_mass": 26780.0 }, "refseq": {}, "gene_names": [ { "name": "CFAP95", "type": "recommended", "evidence": [ { "id": "A0A287B1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0" } ] }, { "name": "C1H9orf135", "type": "synonym", "evidence": [ { "id": "A0A287B1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 95", "type": "synonym", "evidence": [ { "id": "A0A287B1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1D0", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CFAP95", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0", "locus": { "chromosome": "1", "start_pos": 223245839, "end_pos": 223153673, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000035668", "url": "https://www.ensembl.org/id/ENSSSCG00000035668" } ] } } ], "crossref": [ { "id": "A0A287B1D0", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1D0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000035668", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035668", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "9CPC", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CPC&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR027905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DWCSSRQ", "url": "https://omabrowser.org/oma/group/DWCSSRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287B1D0", "url": "https://www.orthodb.org/?gene=A0A287B1D0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35069", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35069", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35069:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35069:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00009cpc", "url": "https://www.rcsb.org/structure/pdb_00009cpc", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CPC", "url": "https://www.rcsb.org/structure/9CPC", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF15139", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15139", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B1D0", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q8R1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q8R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q8R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q8R1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESSDSSCRDWCSGRQYRFELGPTDLTERKGSLTLRSHHKKYSKPVLVYSWNHDREAYPKDYDIEGPEEVKKLCNSTYCRLGTHEPTVWKSETHEKMAQVYLNTEFTEIKSKALLNEETISSGIIERDTGLPATGFGALFTKHPPDWRKMYTLTTYAEEYAPPYQYQPFDYPCQDDDYSVVHRKCRSQFTDLNGSKRFGINTWHDESGIYANSYLKRKLYSLTTSPIAPF", "length": 230, "header": "tr|A0A287B1D0-1|A0A287B1D0_PIG Isoform 1 of Cilia and flagella associated protein 95 OS=Sus scrofa OX=9823 GN=CFAP95 PE=1 SV=1 CANONICAL=A0A287B1D0-1" }, "isoforms": [ { "isoform_ac": "A0A287B1D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0/entry#A0A287B1D0-1", "sequence": { "sequence": "MESSDSSCRDWCSGRQYRFELGPTDLTERKGSLTLRSHHKKYSKPVLVYSWNHDREAYPKDYDIEGPEEVKKLCNSTYCRLGTHEPTVWKSETHEKMAQVYLNTEFTEIKSKALLNEETISSGIIERDTGLPATGFGALFTKHPPDWRKMYTLTTYAEEYAPPYQYQPFDYPCQDDDYSVVHRKCRSQFTDLNGSKRFGINTWHDESGIYANSYLKRKLYSLTTSPIAPF", "length": 230, "header": "tr|A0A287B1D0-1|A0A287B1D0_PIG Isoform 1 of Cilia and flagella associated protein 95 OS=Sus scrofa OX=9823 GN=CFAP95 PE=1 SV=1 CANONICAL=A0A287B1D0-1" }, "locus": { "chromosome": "1", "start_pos": 223245747, "end_pos": 223153788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039324.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039324.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049965.1", "url": "https://www.ensembl.org/id/ENSSSCP00000049965.1" } ] } }, { "isoform_ac": "A0A5G2Q8R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0/entry#A0A5G2Q8R1-1", "sequence": { "sequence": "MESSDSSCRDWCSGRQYRFELGPTDLTERKGSLTLRSHHKKYSKPVLVYSWNHDREAYPKDYDIEGPEEVKKLCNSTYCRLGTHEPTVWKSETHEKMAQVYLNTEFTEIKSKALLNEETISSGIIERDTGLPATGFGALFTKHPPDWRKMIILVKMMIIQ", "length": 160, "header": "tr|A0A5G2Q8R1-1|A0A287B1D0_PIG Computationally mapped isoform of Cilia and flagella associated protein 95 OS=Sus scrofa OX=9823 GN=CFAP95 PE=1 SV=1 CANONICAL=A0A287B1D0-1" }, "locus": { "chromosome": "1", "start_pos": 223245595, "end_pos": 223153788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078975.1", "url": "https://www.ensembl.org/id/ENSSSCT00000078975.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060286.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060286.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1D0", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Structural diversity of axonemes across mammalian motile cilia.", "journal": "Nature", "date": "2025", "authors": "Leung Miguel Ricardo, Sun Chen, Zeng Jianwei, Anderson Jacob R, Niu Qingwei, Huang Wei, Noteborn Willem E M, Brown Alan, Zeev-Ben-Mordehai Tzviya, Zhang Rui", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1D0", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0" } ], "reference": [ { "type": "PubMed", "id": "39743588", "url": "https://glygen.org/publication/PubMed/39743588" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZWG8-1", "protein_name": "Cilia and flagella associated protein 95", "gene_name": "Cfap95", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTFNSSCHECFKRKERWYEIGPTDLLERKGSLTLRSQDKKYSGPVLVYSWHRNREAFPKDYDMEDPKVATNLCKSTYHRLGTDSPRWVSEAQEQMSQVLVNKDFLEKKKKALVHDETMCLGILESDPQLLPSGFREASMEPPPDPRKQCYSTTYSEDYVPQYEYPPPACPLQDDYSIVHRKCRSQFTDLNGSKRFGINKWHDESGIYANSKAKQKLYALAGNPIVPL", "length": 228 }, "evidence": [ { "id": "A0A287B1D0", "url": "https://omabrowser.org/oma/group/A0A287B1D0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32L77-1", "protein_name": "Cilia- and flagella-associated protein 95", "gene_name": "CFAP95", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSSDSSCQEWCSHGQYWLELGPTDLMERKGSLTLRSHHKKYSKPVLVYSWHRDRETYPKDYDIEGPEEVKKLCNSTYRRLGTSEPPVWISETREKMAQVCLNTKLAKIKSKALLNEETMNSGIIERDTGLPATGFGALFTRHSPDWSKMCTLTTYAEEYAPPYEYQPLGDPCQDDDYSIVHRKCRSQFTDLDGSKRVGINTWHDESGIYANSYVKRKLYSLTGGPIAPFLK", "length": 232 }, "evidence": [ { "id": "A0A287B1D0", "url": "https://omabrowser.org/oma/group/A0A287B1D0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5VTT2-1", "protein_name": "Cilia- and flagella-associated protein 95", "gene_name": "CFAP95", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSLDRSCQDWCDRKQHWLEIGPPDLVERKGSLTLRSHHKKYSKPVLVYSWHRDREAFPKGYDIEGPEKVKKLCNSTYRRLGTDESPIWTSETHEKLSQMCLNTEWVEMKSKALLNEETVSSGIIERVTGLPATGFGAVFPRHPPDWSKMCALTTYSEDYVPPYDYQPHAYPCQDDYSIVHRKCRSQFTDLNGSKRFGINTWHDESGIYANSDVKQKLYPLTSGPIVPI", "length": 229 }, "evidence": [ { "id": "A0A287B1D0", "url": "https://omabrowser.org/oma/group/A0A287B1D0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQC3-1", "protein_name": "Cilia- and flagella-associated protein 95", "gene_name": "Cfap95", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTFDSQCHECFESKERWYEIGPTDLLERKGSLTLRSHHKKYSEPVLVYSWHRNREAFPKDYDIESLETVKNLCMSTYKRFGSDSPRWMSEAREQMAQVLVNKDLVEKKKTGLLDEETLCPGILERDPELPPTGFRDVPMESPPDPRKPCFSTTYSEDFTPQYEYPPPACPRREEYSIVHRKCRSQFTDLNGSKRLGINTWHDESGIYANSEAKQKLYALARNPIVPF", "length": 228 }, "evidence": [ { "id": "A0A287B1D0", "url": "https://omabrowser.org/oma/group/A0A287B1D0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1D0", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1D0", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0" } ], "pmid": "" }, { "name": "axonemal A tubule inner sheath", "id": "GO:0160111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160111", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1D0", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1D0", "url": "https://www.uniprot.org/uniprotkb/A0A287B1D0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1D0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 230, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1D0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1D0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1E2-1", "uniprot_ac": "A0A287B1E2", "uniprot_id": "A0A287B1E2_PIG", "mass": { "chemical_mass": 15105.0, "monoisotopic_mass": 15105.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A287B1E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1E2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1E2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1E2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A287B1E2", "locus": {} } ], "crossref": [ { "id": "A0A287B1E2", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1E2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034846", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034846", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "PTHR46703", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46703", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46703:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46703:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A287B1E2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1E2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQSVLRDGRVPFRRDGRWPPLPSADRKGVGFRSPNPEWRRWAPRGVQCGNATDPGEAGGSPGESSLFFVKGRAPWNGFAPREGPVPWKASRFRRRPVSSRWPLKIRGRGCKSRAGPYPYPQQVSKVNSLWHVGT", "length": 135, "header": "tr|A0A287B1E2-1|A0A287B1E2_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A287B1E2-1" }, "isoforms": [ { "isoform_ac": "A0A287B1E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1E2/entry#A0A287B1E2-1", "sequence": { "sequence": "MGQSVLRDGRVPFRRDGRWPPLPSADRKGVGFRSPNPEWRRWAPRGVQCGNATDPGEAGGSPGESSLFFVKGRAPWNGFAPREGPVPWKASRFRRRPVSSRWPLKIRGRGCKSRAGPYPYPQQVSKVNSLWHVGT", "length": 135, "header": "tr|A0A287B1E2-1|A0A287B1E2_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A287B1E2-1" }, "locus": { "chromosome": "AEMK02000695.1", "start_pos": 14517, "end_pos": 14113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039225.2", "url": "https://www.ensembl.org/id/ENSSSCT00000039225.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049915.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049915.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1E2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1E2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1E2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 135, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1E2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1E2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1G6-1", "uniprot_ac": "A0A287B1G6", "uniprot_id": "A0A287B1G6_PIG", "mass": { "chemical_mass": 57018.0, "monoisotopic_mass": 57018.0 }, "refseq": {}, "gene_names": [ { "name": "PTX4", "type": "recommended", "evidence": [ { "id": "A0A287B1G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G6" } ] } ], "protein_names": [ { "name": "Pentraxin 4", "type": "synonym", "evidence": [ { "id": "A0A287B1G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PTX4", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G6", "locus": { "chromosome": "3", "start_pos": 40390812, "end_pos": 40382667, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037262", "url": "https://www.ensembl.org/id/ENSSSCG00000037262" } ] } } ], "crossref": [ { "id": "A0A287B1G6", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1G6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000037262", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037262", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19277:SF122", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19277:SF122", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B1G6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAAGARGRQHLPLRVCLRMRCPGRKSLPFLLIFVPVSLHGALSQEASPAGQRKPFFERLRRLEEQFRRSQEATLAHLRLVASNHSPSLDIEARFQSLAQENQAMALALSRSQAVVQGDLGHLKTWMRKMQRRSRKLDRRLLALDAALGEGSTRREREQEAQRGALASLALDVQALRDALARLMPLVQSQGARLAALEGQLQVVAPGVTAAQPRPSSPSSPQLQGGRQALGAPPAPGDACLDSTRRLQGTLEPPGPGSPQVSGRKPGQQDEVPPEILQPGPRAPLPERLHCNAIFLRPGFLTGLRALSVCSWVPTASGHLGTLLSYATEENDNKLVLHGRDSLVPGSMHFVIGDPDFRELPLQPLLDGRWHHVCVIWTSALGRYWVHVDRRVVATSSRFREGYKIPPGGSLVLGQEQDSVGGGFDSSEAFVGTWQAWVSNLATGKELLMGAILTLANAALVGGFVQRSNCTCLPLCPEGLNPSCCAPTVGTALQRVPTQTEGQAAASDLGWAWLPSNMGRGHSTGPGEGP", "length": 530, "header": "tr|A0A287B1G6-1|A0A287B1G6_PIG Isoform 1 of Pentraxin 4 OS=Sus scrofa OX=9823 GN=PTX4 PE=4 SV=3 CANONICAL=A0A287B1G6-1" }, "isoforms": [ { "isoform_ac": "A0A287B1G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G6/entry#A0A287B1G6-1", "sequence": { "sequence": "MGAAGARGRQHLPLRVCLRMRCPGRKSLPFLLIFVPVSLHGALSQEASPAGQRKPFFERLRRLEEQFRRSQEATLAHLRLVASNHSPSLDIEARFQSLAQENQAMALALSRSQAVVQGDLGHLKTWMRKMQRRSRKLDRRLLALDAALGEGSTRREREQEAQRGALASLALDVQALRDALARLMPLVQSQGARLAALEGQLQVVAPGVTAAQPRPSSPSSPQLQGGRQALGAPPAPGDACLDSTRRLQGTLEPPGPGSPQVSGRKPGQQDEVPPEILQPGPRAPLPERLHCNAIFLRPGFLTGLRALSVCSWVPTASGHLGTLLSYATEENDNKLVLHGRDSLVPGSMHFVIGDPDFRELPLQPLLDGRWHHVCVIWTSALGRYWVHVDRRVVATSSRFREGYKIPPGGSLVLGQEQDSVGGGFDSSEAFVGTWQAWVSNLATGKELLMGAILTLANAALVGGFVQRSNCTCLPLCPEGLNPSCCAPTVGTALQRVPTQTEGQAAASDLGWAWLPSNMGRGHSTGPGEGP", "length": 530, "header": "tr|A0A287B1G6-1|A0A287B1G6_PIG Isoform 1 of Pentraxin 4 OS=Sus scrofa OX=9823 GN=PTX4 PE=4 SV=3 CANONICAL=A0A287B1G6-1" }, "locus": { "chromosome": "3", "start_pos": 40390809, "end_pos": 40387092, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041192.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041192.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050250.3", "url": "https://www.ensembl.org/id/ENSSSCP00000050250.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1G6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1G6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 530, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1G6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1G6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B1G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1G6" }, { "id": "PS51828", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51828" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pentraxin (PTX)", "eco_id": "ECO_0000259", "start_pos": 279, "end_pos": 472, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 469, "end_pos": 471 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1H8-1", "uniprot_ac": "A0A287B1H8", "uniprot_id": "A0A287B1H8_PIG", "mass": { "chemical_mass": 52552.0, "monoisotopic_mass": 52552.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC174", "type": "recommended", "evidence": [ { "id": "A0A287B1H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H8" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 174", "type": "synonym", "evidence": [ { "id": "A0A287B1H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1H8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CCDC174", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H8", "locus": { "chromosome": "13", "start_pos": 69895325, "end_pos": 69915655, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040702", "url": "https://www.ensembl.org/id/ENSSSCG00000040702" } ] } } ], "crossref": [ { "id": "A0A287B1H8", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1H8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000040702", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000040702", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR025066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15885", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15885", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15885:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15885:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25449", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25449", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B1H8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRRKYSLNFYLVDLKAELFRKQEEFKQEKLLKDAGVLGKPKTTNKKPSIWSKQNAGVSNRAEKDAEQKLEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDRHKEMETVGANRDSRRTGKRDDDEEILSEKDIPPPQDPSEEWVDYVDSLGRSRRCMKKDLPDLLEMDKNLQGRLFVSPANEKTLLSEDMRKELQRQQWEEEEREALRRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAMLEARLAKLRQKKMKKSKEDGAEEENTDGGVIGPFCQSSKVEVIVQERKDTRPGVPHIREWDRGKDFSFGYWSKRQSDLRSERDPEFAPPSDYFVGQKRTGSLSSQTWNRPAPAQSDPVLHSGQSQDPASSHSSSTPSPSGPPQAPMVTFETLDDMISYYKQVT", "length": 451, "header": "tr|A0A287B1H8-1|A0A287B1H8_PIG Isoform 1 of Coiled-coil domain containing 174 OS=Sus scrofa OX=9823 GN=CCDC174 PE=4 SV=3 CANONICAL=A0A287B1H8-1" }, "isoforms": [ { "isoform_ac": "A0A287B1H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H8/entry#A0A287B1H8-1", "sequence": { "sequence": "MDRRKYSLNFYLVDLKAELFRKQEEFKQEKLLKDAGVLGKPKTTNKKPSIWSKQNAGVSNRAEKDAEQKLEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDRHKEMETVGANRDSRRTGKRDDDEEILSEKDIPPPQDPSEEWVDYVDSLGRSRRCMKKDLPDLLEMDKNLQGRLFVSPANEKTLLSEDMRKELQRQQWEEEEREALRRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAMLEARLAKLRQKKMKKSKEDGAEEENTDGGVIGPFCQSSKVEVIVQERKDTRPGVPHIREWDRGKDFSFGYWSKRQSDLRSERDPEFAPPSDYFVGQKRTGSLSSQTWNRPAPAQSDPVLHSGQSQDPASSHSSSTPSPSGPPQAPMVTFETLDDMISYYKQVT", "length": 451, "header": "tr|A0A287B1H8-1|A0A287B1H8_PIG Isoform 1 of Coiled-coil domain containing 174 OS=Sus scrofa OX=9823 GN=CCDC174 PE=4 SV=3 CANONICAL=A0A287B1H8-1" }, "locus": { "chromosome": "13", "start_pos": 69915655, "end_pos": 69898817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062059.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062059.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049946.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049946.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1H8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1H8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1H8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1H8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 451, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1H8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1H8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B1H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H8" }, { "id": "PF25449", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25449" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCDC174 alpha/beta GRSR", "eco_id": "ECO_0000259", "start_pos": 159, "end_pos": 188, "start_aa": "Trp", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1I5-1", "uniprot_ac": "A0A287B1I5", "uniprot_id": "A0A287B1I5_PIG", "mass": { "chemical_mass": 27076.0, "monoisotopic_mass": 27076.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100521785", "type": "recommended", "evidence": [ { "id": "A0A287B1I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A287B1I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1I5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100521785", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5", "locus": {} } ], "crossref": [ { "id": "A0A287B1I5", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1I5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000036748", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036748", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23232:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23232:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B1I5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPHLVKKSLTFKDVAVTFSKDEWKQLVPTQRALYREVMLENYQDFISLGLLLPKADVIFQLKRGDEPWKLEFWEAEERDVPRGLYEPDQKGRLDNQDSTQRQNVSENVKSQETLIDKLRKDVLDPVLGQENPEGTMKENPSGETPREKDLRQVSTPAKNTDSKGRSFKCGICGKTLFNHLSLTRHQRTHTGEKPYDCEECGKAFSYRSCLKKHLMSHSGKSPFECNECGKTFYD", "length": 235, "header": "tr|A0A287B1I5-1|A0A287B1I5_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN=LOC100521785 PE=4 SV=1 CANONICAL=A0A287B1I5-1" }, "isoforms": [ { "isoform_ac": "A0A287B1I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5/entry#A0A287B1I5-1", "sequence": { "sequence": "MGPHLVKKSLTFKDVAVTFSKDEWKQLVPTQRALYREVMLENYQDFISLGLLLPKADVIFQLKRGDEPWKLEFWEAEERDVPRGLYEPDQKGRLDNQDSTQRQNVSENVKSQETLIDKLRKDVLDPVLGQENPEGTMKENPSGETPREKDLRQVSTPAKNTDSKGRSFKCGICGKTLFNHLSLTRHQRTHTGEKPYDCEECGKAFSYRSCLKKHLMSHSGKSPFECNECGKTFYD", "length": 235, "header": "tr|A0A287B1I5-1|A0A287B1I5_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN=LOC100521785 PE=4 SV=1 CANONICAL=A0A287B1I5-1" }, "locus": { "chromosome": "3", "start_pos": 46078784, "end_pos": 46072389, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060369.1", "url": "https://www.ensembl.org/id/ENSSSCT00000060369.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050092.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050092.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1I5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1I5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1I5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1I5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1I5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1I5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1I5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 235, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1I5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1I5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B1I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 168, "end_pos": 195, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287B1I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1I5" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 81, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1N2-1", "uniprot_ac": "A0A287B1N2", "uniprot_id": "A0A287B1N2_PIG", "mass": { "chemical_mass": 10681.0, "monoisotopic_mass": 10681.0 }, "refseq": { "ac": "XP_013838010", "name": "MAP3K7 C-terminal-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013838010" }, "gene_names": [ { "name": "MAP3K7CL", "type": "recommended", "evidence": [ { "id": "A0A287B1N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1N2" } ] }, { "name": "MAP3K7CL", "type": "synonym", "evidence": [ { "id": "XP_013838010", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013838010" } ] } ], "protein_names": [ { "name": "MAP3K7 C-terminal like", "type": "synonym", "evidence": [ { "id": "A0A287B1N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1N2/entry#names_and_taxonomy" } ] }, { "name": "MAP3K7 C-terminal-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013838010", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013838010" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1N2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1N2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MAP3K7CL", "url": "https://www.uniprot.org/uniprotkb/A0A287B1N2", "locus": { "chromosome": "13", "start_pos": 192534821, "end_pos": 192489751, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000038281", "url": "https://www.ensembl.org/id/ENSSSCG00000038281" } ] } } ], "crossref": [ { "id": "A0A287B1N2", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1N2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000038281", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000038281", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100624256", "url": "https://www.ncbi.nlm.nih.gov/gene/100624256", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR042800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624256", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624256", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B1N2", "url": "https://www.orthodb.org/?gene=A0A287B1N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47140:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47140:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27575", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27575", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013838010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013838010", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B1N2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1N2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESMQVFKQHCQIAEEYREVKKEIALLEERKKELIAKLDQAEKEKLDAAQLVREFEALTEENRTLKLAQSQCVEQLEKLRIQYQKRQGSS", "length": 90, "header": "tr|A0A287B1N2-1|A0A287B1N2_PIG Isoform 1 of MAP3K7 C-terminal like OS=Sus scrofa OX=9823 GN=MAP3K7CL PE=4 SV=2 CANONICAL=A0A287B1N2-1" }, "isoforms": [ { "isoform_ac": "A0A287B1N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1N2/entry#A0A287B1N2-1", "sequence": { "sequence": "MESMQVFKQHCQIAEEYREVKKEIALLEERKKELIAKLDQAEKEKLDAAQLVREFEALTEENRTLKLAQSQCVEQLEKLRIQYQKRQGSS", "length": 90, "header": "tr|A0A287B1N2-1|A0A287B1N2_PIG Isoform 1 of MAP3K7 C-terminal like OS=Sus scrofa OX=9823 GN=MAP3K7CL PE=4 SV=2 CANONICAL=A0A287B1N2-1" }, "locus": { "chromosome": "13", "start_pos": 192533860, "end_pos": 192519344, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042000.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042000.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050315.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050315.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1N2", "url": "https://www.uniprot.org/uniprotkb/A0A287B1N2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624256", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624256", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1N2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 90, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1N2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1N2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1T8-1", "uniprot_ac": "A0A287B1T8", "uniprot_id": "A0A287B1T8_PIG", "mass": { "chemical_mass": 36515.0, "monoisotopic_mass": 36515.0 }, "refseq": {}, "gene_names": [ { "name": "LOC106508184", "type": "recommended", "evidence": [ { "id": "A0A287B1T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8" } ] } ], "protein_names": [ { "name": "B30.2/SPRY domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A287B1T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC106508184", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8", "locus": {} } ], "crossref": [ { "id": "A0A287B1T8", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1T8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000032990", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000032990", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15819", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15819", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B1T8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B489", "url": "https://www.uniprot.org/uniprotkb/A0A287B489", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B489-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B489-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B9G5", "url": "https://www.uniprot.org/uniprotkb/A0A287B9G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B9G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B9G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLF0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFFPLSSFLSSCLYLMLPALCSTSVPPTFCCFCISTYILNLTILTYYLYLKPDRFYLSCFLKCNTEVIQNRKRKSEGFKTRKGIMTGSNGKDNRRKWRRKKAKGFPMFSFAAWRDAPIYPDWRKEEFEAANVTLDEATAHPALLVSERGRQVTWQETCQDLPSSTQRFNSIPCVLGQLRINSGRAHWEVEVGDMQSWDLGICRENVTRKGAFIMSPQNGFWAIRLYDGDYWALTSPETSLPLRERPLKVGIFLDYEAGDVSFYNMTDGSHIFTFPQNTFYGVLRPLFRLWSSDSGSLTICSAEGECTDVIHKPTLQVK", "length": 318, "header": "tr|A0A287B1T8-1|A0A287B1T8_PIG Isoform 1 of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN=LOC106508184 PE=1 SV=1 CANONICAL=A0A287B1T8-1" }, "isoforms": [ { "isoform_ac": "A0A287B1T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8/entry#A0A287B1T8-1", "sequence": { "sequence": "MFFPLSSFLSSCLYLMLPALCSTSVPPTFCCFCISTYILNLTILTYYLYLKPDRFYLSCFLKCNTEVIQNRKRKSEGFKTRKGIMTGSNGKDNRRKWRRKKAKGFPMFSFAAWRDAPIYPDWRKEEFEAANVTLDEATAHPALLVSERGRQVTWQETCQDLPSSTQRFNSIPCVLGQLRINSGRAHWEVEVGDMQSWDLGICRENVTRKGAFIMSPQNGFWAIRLYDGDYWALTSPETSLPLRERPLKVGIFLDYEAGDVSFYNMTDGSHIFTFPQNTFYGVLRPLFRLWSSDSGSLTICSAEGECTDVIHKPTLQVK", "length": 318, "header": "tr|A0A287B1T8-1|A0A287B1T8_PIG Isoform 1 of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN=LOC106508184 PE=1 SV=1 CANONICAL=A0A287B1T8-1" }, "locus": { "chromosome": "AEMK02000422.1", "start_pos": 9601, "end_pos": 7611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065551.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065551.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050373.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050373.1" } ] } }, { "isoform_ac": "A0A287B489-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8/entry#A0A287B489-1", "sequence": { "sequence": "FFIFCILYFKTRGSLHGHSEKLQKVNGELQDETDTLRKKNEKLQKVNGELQDETDTLRKKNEKLQKVNGELQDETDTLRKKNEKLQKVNGALQDEIARRKAQFKKAWRDAPIYPDWRKEEFEAANVTLDEATAHPALLVSERGRQVTWQETCQDLPSSTQRFNSIPCVLGQLRINSGRAHWEVEVGDMQSWDLGICRENVTRKGAFIMSPQNGFWAIRLYDGDYWALTSPETSLPLRERPLKVGIFLDYEAGDVSFYNMTDGSHIFTFPQNTFYGVLRPLFRLWSSDSGSLTICSAEGECTDVIHKPTLQVK", "length": 312, "header": "tr|A0A287B489-1|A0A287B489_PIG Computationally mapped isoform of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN=LOC106508184 PE=1 SV=2 CANONICAL=A0A287B1T8-1" }, "locus": { "chromosome": "AEMK02000422.1", "start_pos": 61857, "end_pos": 7611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061135.2", "url": "https://www.ensembl.org/id/ENSSSCT00000061135.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050928.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050928.2" } ] } }, { "isoform_ac": "A0A287B9G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8/entry#A0A287B9G5-1", "sequence": { "sequence": "GELQDETDTLRKKNEKLQKVNGKIADIPLLLSPSEEKLQKINGALQDEIARRKAQFKKAWRDAPIYPDWRKEEFEAANVTLDEATAHPALLVSERGRQVTWQETCQDLPSSTQRFNSIPCVLGQLRINSGRAHWEVEVGDMQSWDLGICRENVTRKGAFIMSPQNGFWAIRLYDGDYWALTSPETSLPLRERPLKVGIFLDYEAGDVSFYNMTDGSHIFTFPQNTFYGVLRPLFRLWSSDSGSLTICSAEGECTDVIHKPTLQVK", "length": 265, "header": "tr|A0A287B9G5-1|A0A287B9G5_PIG Computationally mapped isoform of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN=LOC106508184 PE=1 SV=3 CANONICAL=A0A287B1T8-1" }, "locus": { "chromosome": "AEMK02000422.1", "start_pos": 26291, "end_pos": 7611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042929.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042929.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053132.3", "url": "https://www.ensembl.org/id/ENSSSCP00000053132.3" } ] } }, { "isoform_ac": "A0A8W4FLF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8/entry#A0A8W4FLF0-1", "sequence": { "sequence": "MYGFKCIFLMKSRNPLISMGVLCFLSARRKAQFKKAWRDAPIYPGDPLVFAANVTLDEATAHPALLVSERGRQVTWQETCQDLPSSTQRFNSIPCVLGQLRINSGRAHWEVEVGDMQSWDLGICRENVTRKGAFIMSPQNGFWAIRLYDGDYWALTSPETSLPLRERPLKVGIFLDYEAGDVSFYNMTDGSHIFTFPQNTFYGVLRPLFRLWSSDSGSLTICSAEGECTDVIHKPTLQVK", "length": 240, "header": "tr|A0A8W4FLF0-1|A0A287B1T8_PIG Computationally mapped isoform of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN=LOC106508184 PE=1 SV=1 CANONICAL=A0A287B1T8-1" }, "locus": { "chromosome": "AEMK02000422.1", "start_pos": 9895, "end_pos": 7611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101275.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101275.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080164.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080164.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FLF0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLF0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1T8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 318, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1T8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1T8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B1T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T8" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 306, "start_aa": "Ala", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1T9-1", "uniprot_ac": "A0A287B1T9", "uniprot_id": "A0A287B1T9_PIG", "mass": { "chemical_mass": 50242.0, "monoisotopic_mass": 50242.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A287B1T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T9", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9", "locus": {} } ], "crossref": [ { "id": "A0A287B1T9", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1T9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003236", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003236", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12035", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12035", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12035:SF99", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12035:SF99", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-198933", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-198933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B1T9", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B5X8", "url": "https://www.uniprot.org/uniprotkb/A0A287B5X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B5X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B5X8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELNGSSLVAQRVKVLALSLLWHRFDPWPGNFLMLGNVTVQEGLCVLVPCKFSYPWSSFGTFSGFWFRQGAGKKHALVATNRLGQKLSEGSQGRFFLLGDPQANNCSLSIRDVTTGDSGTYFFQIETSFHQHAYQDRPLSLGVTALTQAPHILMPETLESGRPRRLTCSVPWACEWGTPPVFSWTSAALPTLGPRTPLSSVVTLTPRPQDHGTSLTCQVMFPASGVTVGRTIQLNVTYAPRNVTVSVFQGNRTALKILQNASSLPVLEGQALQLLCVADGNPPAQLSWFRGSPAPNATPISSTTILELPGLGTVPGEVTCRAQNPLGSQNLSLSLLVVWNKPANLLSPCRPPPAAGSLLLLGGQGSPLQLLLPSPARPLPALAPGGGAAGRELQQRLDQGHLQLHRALGQQLPEPGRGAQLQPQTQLRGPERLRVPGRHCPAAARSGGLLRGRCLGDRNGDPFVSLLGLP", "length": 470, "header": "tr|A0A287B1T9-1|A0A287B1T9_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A287B1T9-1" }, "isoforms": [ { "isoform_ac": "A0A287B1T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9/entry#A0A287B1T9-1", "sequence": { "sequence": "MELNGSSLVAQRVKVLALSLLWHRFDPWPGNFLMLGNVTVQEGLCVLVPCKFSYPWSSFGTFSGFWFRQGAGKKHALVATNRLGQKLSEGSQGRFFLLGDPQANNCSLSIRDVTTGDSGTYFFQIETSFHQHAYQDRPLSLGVTALTQAPHILMPETLESGRPRRLTCSVPWACEWGTPPVFSWTSAALPTLGPRTPLSSVVTLTPRPQDHGTSLTCQVMFPASGVTVGRTIQLNVTYAPRNVTVSVFQGNRTALKILQNASSLPVLEGQALQLLCVADGNPPAQLSWFRGSPAPNATPISSTTILELPGLGTVPGEVTCRAQNPLGSQNLSLSLLVVWNKPANLLSPCRPPPAAGSLLLLGGQGSPLQLLLPSPARPLPALAPGGGAAGRELQQRLDQGHLQLHRALGQQLPEPGRGAQLQPQTQLRGPERLRVPGRHCPAAARSGGLLRGRCLGDRNGDPFVSLLGLP", "length": 470, "header": "tr|A0A287B1T9-1|A0A287B1T9_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A287B1T9-1" }, "locus": { "chromosome": "6", "start_pos": 58431133, "end_pos": 58428065, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032772.4", "url": "https://www.ensembl.org/id/ENSSSCT00000032772.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050131.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050131.2" } ] } }, { "isoform_ac": "A0A287B5X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9/entry#A0A287B5X8-1", "sequence": { "sequence": "GWTSACLPLLLERVRGQDPFKSDSWYQLELQQNVTVQEGLCVLVPCKFSYPWSSFGTFSGFWFRQGAGKKHALVATNRLGQKLSEGSQGRFFLLGDPQANNCSLSIRDVTTGDSGTYFFQIETSFHQHAYQDRPLSLGVTALTQAPHILMPETLESGRPRRLTCSVPWACEWGTPPVFSWTSAALPTLGPRTPLSSVVTLTPRPQDHGTSLTCQVMFPASGVTVGRTIQLNVTCERWAGSGERSRQTLKILQNASSLPVLEGQALQLLCVADGNPPAQLSWFRGSPAPNATPISSTTILELPGLGTVPGEVTCRAQNPLGSQNLSLSLLVVCEPPPAAGSLLLLGGQGSPLQLLLPSPARPLPALAPGGGAAGRELQQRLDQGHLQLHRALGQQLPEPGRGAQLQPQTQLRGPERLRVPGRHCPAAARSGGLLRGRCLGDRNGDPFVSLLGLP", "length": 453, "header": "tr|A0A287B5X8-1|A0A287B5X8_PIG Computationally mapped isoform of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A287B1T9-1" }, "locus": { "chromosome": "6", "start_pos": 58431133, "end_pos": 58427632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033542.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033542.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051485.2", "url": "https://www.ensembl.org/id/ENSSSCP00000051485.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T9", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-198933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-198933", "resource": "Reactome", "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T9", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T9", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T9", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T9", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9" } ], "pmid": "" }, { "name": "sialic acid binding", "id": "GO:0033691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033691", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1T9", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1T9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 470, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1T9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1T9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B1T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1T9" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 140, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 235, "end_pos": 237 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 251, "end_pos": 253 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1U3-1", "uniprot_ac": "A0A287B1U3", "uniprot_id": "A0A287B1U3_PIG", "mass": { "chemical_mass": 37833.0, "monoisotopic_mass": 37833.0 }, "refseq": { "ac": "XP_003483205", "name": "zinc finger protein 660", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483205" }, "gene_names": [ { "name": "ZNF660", "type": "recommended", "evidence": [ { "id": "A0A287B1U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3" } ] }, { "name": "ZNF660", "type": "synonym", "evidence": [ { "id": "XP_003483205", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483205" } ] } ], "protein_names": [ { "name": "Zinc finger protein 660", "type": "synonym", "evidence": [ { "id": "A0A287B1U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 660", "type": "synonym", "evidence": [ { "id": "XP_003483205", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483205" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U3", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF660", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3", "locus": { "chromosome": "13", "start_pos": 27868533, "end_pos": 27867553, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011310", "url": "https://www.ensembl.org/id/ENSSSCG00000011310" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011310", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011310", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100513047", "url": "https://www.ncbi.nlm.nih.gov/gene/100513047", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513047", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513047", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KTRNFKQ", "url": "https://omabrowser.org/oma/group/KTRNFKQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287B1U3", "url": "https://www.orthodb.org/?gene=A0A287B1U3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003483205", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483205", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B1U3", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRKTRNFKPKTVKDNKTLIEVSDQESEKDDPTINERIQAEKRQYVCTECGKAFSQSANLTVHERIHTGEKPYKCKECGKAFSHSSNLVVHRRIHTGLKPYTCSECGKSFSGKSHLIRHQGIHSGEKTYECKECGKAFSRSSGLISHHRVHTGEKPYTCIECGKAFSRSSNLTQHQRMHKGKKVYKCKECGKTCISNTKIMDHQRIHTGEKPYECDECGKAFILKKTLNEHQRLHRREKPYKCKECGKAFTSNRNLIDHQRVHTGEKPYKCNECGKTFRQTSQVILHLRTHTKEKPYKCNECAKAYRYSSQLIQHQRKHSEEKETS", "length": 326, "header": "tr|A0A287B1U3-1|A0A287B1U3_PIG Isoform 1 of Zinc finger protein 660 OS=Sus scrofa OX=9823 GN=ZNF660 PE=1 SV=1 CANONICAL=A0A287B1U3-1" }, "isoforms": [ { "isoform_ac": "A0A287B1U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3/entry#A0A287B1U3-1", "sequence": { "sequence": "MRRKTRNFKPKTVKDNKTLIEVSDQESEKDDPTINERIQAEKRQYVCTECGKAFSQSANLTVHERIHTGEKPYKCKECGKAFSHSSNLVVHRRIHTGLKPYTCSECGKSFSGKSHLIRHQGIHSGEKTYECKECGKAFSRSSGLISHHRVHTGEKPYTCIECGKAFSRSSNLTQHQRMHKGKKVYKCKECGKTCISNTKIMDHQRIHTGEKPYECDECGKAFILKKTLNEHQRLHRREKPYKCKECGKAFTSNRNLIDHQRVHTGEKPYKCNECGKTFRQTSQVILHLRTHTKEKPYKCNECAKAYRYSSQLIQHQRKHSEEKETS", "length": 326, "header": "tr|A0A287B1U3-1|A0A287B1U3_PIG Isoform 1 of Zinc finger protein 660 OS=Sus scrofa OX=9823 GN=ZNF660 PE=1 SV=1 CANONICAL=A0A287B1U3-1" }, "locus": { "chromosome": "13", "start_pos": 27868530, "end_pos": 27867553, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012381.4", "url": "https://www.ensembl.org/id/ENSSSCT00000012381.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050136.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050136.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U3", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513047", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513047", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KBC6-1", "protein_name": "Zinc finger protein 660", "gene_name": "Znf660", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRKMGKFKHKTLEDSKSPAEGSDQEGENSGHQFCASATEKRGHGGRRQYVCPECGKAFSQSANLTVHERIHTGEKPYKCTVCGKAFSHSSNLVVHRRIHTGLKPYTCRDCGKSFSGKSHLIGHQEVHSGEKTYECKECGKAFSRSSGLIAHHRVHTGEKPYTCSECGKAFSRSSNLTQHQRTHRGKKVYKCKECGKTCGSNTKIIDHQRIHTGEKPYECAECGKTFILRKALNEHQRLHRREKPYKCKECGKAFTSNRNLTDHQRVHTGEKPYKCNECGKTFRQTSQVILHLRTHTKEKPYKCSECGKAYRYSSQLIQHQRKHNEEKEALLFTGQV", "length": 337 }, "evidence": [ { "id": "A0A287B1U3", "url": "https://omabrowser.org/oma/group/A0A287B1U3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1MAT5-1", "protein_name": "Zinc finger protein 660", "gene_name": "ZNF660", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRRQTRNFKQKTVQDNKTLTEVSDQESEKDGPTINERIQAAKRQYVCSECGKAFSQSANLTVHERIHTGEKPYKCKECGKAFSHSSNLVVHRRIHTGLKPYTCSECGKSFSGKSHLIRHQGIHSGEKTYECKECGKAFSRSSGLISHHRVHTGEKPYTCIECGKAFSRSSNLTQHQRMHKGKKVYKCKECGKTCVSNTKIMDHQRIHTGEKPYECDECGKAFILKKTLNEHQRLHRREKPYKCNECGKAFTSNRNLIDHQRVHTGEKPYKCNECGKTFRQTSQVILHLRTHTKEKPYKCSECGKAYRYSSQLIQHQRKHNEEKEMS", "length": 326 }, "evidence": [ { "id": "A0A287B1U3", "url": "https://omabrowser.org/oma/group/A0A287B1U3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AZW8-1", "protein_name": "Zinc finger protein 660", "gene_name": "ZNF660", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRKTRNFKHKTVKDNKVLTEGSDQESEKDNSQCCDPATNERVQAEKRQYVCTECGKAFSQSANLTVHERIHTGEKPYKCKECGKAFSHSSNLVVHRRIHTGLKPYTCSECGKSFSGKSHLIRHQGIHSGEKTYECKECGKAFSRSSGLISHHRVHTGEKPYSCIECGKAFSRSSNLTQHQRMHRGKKVYKCKECGKTCGSNTKIMDHQRIHTGEKPYECDECGKTFILRKTLNEHQRLHRREKPYKCNECGKAFTSNRNLVDHQRVHTGEKPYKCNECGKTFRQTSQVILHLRTHTKEKPYKCSECGKAYRYSSQLIQHQRKHNEEKETS", "length": 331 }, "evidence": [ { "id": "A0A287B1U3", "url": "https://omabrowser.org/oma/group/A0A287B1U3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U3", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U3", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U3", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U3", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U3", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U3", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B1U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U3" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 72, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1U5-1", "uniprot_ac": "A0A287B1U5", "uniprot_id": "A0A287B1U5_PIG", "mass": { "chemical_mass": 22482.0, "monoisotopic_mass": 22482.0 }, "refseq": {}, "gene_names": [ { "name": "NOL4L", "type": "recommended", "evidence": [ { "id": "A0A287B1U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5" } ] }, { "name": "COMMD7", "type": "synonym", "evidence": [ { "id": "A0A287B1U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5" } ] } ], "protein_names": [ { "name": "COMM domain containing 7", "type": "synonym", "evidence": [ { "id": "A0A287B1U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NOL4L", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5", "locus": { "chromosome": "17", "start_pos": 36073655, "end_pos": 36201145, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007249", "url": "https://www.ensembl.org/id/ENSSSCG00000007249" } ] } } ], "crossref": [ { "id": "A0A287B1U5", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1U5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000007249", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007249", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04755", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04755", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR017920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16231:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16231:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B1U5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S514", "url": "https://www.uniprot.org/uniprotkb/F1S514", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S514-1", "url": "https://www.uniprot.org/uniprotkb/F1S514-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRLHCTQDPVPEAVGGDMQQLNQLGAQFSALTEVLFHFLTEPKEVERFLAQLSEFATTNQISLGPLRSIVKSFLLVPNGALKKSLTAEQVRADFLTLGLSEEKATYFSEKWKQNAPTLARWAIGQTLMINQLIDMEWKFGVTSGSSELEKVGSIFLQLKLVVKKGNQTENLYIELTLPQFYSFLHEMERVRTSMECFS", "length": 199, "header": "tr|A0A287B1U5-1|A0A287B1U5_PIG Isoform 1 of COMM domain containing 7 OS=Sus scrofa OX=9823 GN=NOL4L PE=4 SV=2 CANONICAL=A0A287B1U5-1" }, "isoforms": [ { "isoform_ac": "A0A287B1U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5/entry#A0A287B1U5-1", "sequence": { "sequence": "MGRLHCTQDPVPEAVGGDMQQLNQLGAQFSALTEVLFHFLTEPKEVERFLAQLSEFATTNQISLGPLRSIVKSFLLVPNGALKKSLTAEQVRADFLTLGLSEEKATYFSEKWKQNAPTLARWAIGQTLMINQLIDMEWKFGVTSGSSELEKVGSIFLQLKLVVKKGNQTENLYIELTLPQFYSFLHEMERVRTSMECFS", "length": 199, "header": "tr|A0A287B1U5-1|A0A287B1U5_PIG Isoform 1 of COMM domain containing 7 OS=Sus scrofa OX=9823 GN=NOL4L PE=4 SV=2 CANONICAL=A0A287B1U5-1" }, "locus": { "chromosome": "17", "start_pos": 36324719, "end_pos": 36301377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062622.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062622.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050209.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050209.2" } ] } }, { "isoform_ac": "F1S514-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5/entry#F1S514-1", "sequence": { "sequence": "MGRLHCTQDPVPEAVGGDMQQLNQLGAQQFSALTEVLFHFLTEPKEVERFLAQLSEFATTNQISLGPLRSIVKSFLLVPNGLSEEKATYFSEKWKQNAPTLARWAIGQTLMINQLIDMEWKFGVTSGSSELEKVGSIFLQLKLVVKKGNQTENLYIELTLPQFYSFLHEMERVRTSMECFS", "length": 181, "header": "tr|F1S514-1|A0A287B1U5_PIG Computationally mapped isoform of COMM domain containing 7 OS=Sus scrofa OX=9823 GN=NOL4L PE=4 SV=2 CANONICAL=A0A287B1U5-1" }, "locus": { "chromosome": "17", "start_pos": 36324719, "end_pos": 36301377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007934.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007934.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007721.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007721.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S514", "url": "https://www.uniprot.org/uniprotkb/F1S514" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5" } ], "pmid": "" }, { "name": "tumor necrosis factor-mediated signaling pathway", "id": "GO:0033209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033209", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "NF-kappaB binding", "id": "GO:0051059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051059", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1U5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 199, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1U5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1U5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B1U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U5" }, { "id": "PS51269", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51269" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "COMM", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 199, "start_aa": "Gln", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1W5-1", "uniprot_ac": "A0A287B1W5", "uniprot_id": "A0A287B1W5_PIG", "mass": { "chemical_mass": 35841.0, "monoisotopic_mass": 35841.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC24", "type": "recommended", "evidence": [ { "id": "A0A287B1W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1W5" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 24", "type": "synonym", "evidence": [ { "id": "A0A287B1W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1W5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1W5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1W5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CCDC24", "url": "https://www.uniprot.org/uniprotkb/A0A287B1W5", "locus": { "chromosome": "6", "start_pos": 167301565, "end_pos": 167305255, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034727", "url": "https://www.ensembl.org/id/ENSSSCG00000034727" } ] } } ], "crossref": [ { "id": "A0A287B1W5", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1W5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034727", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034727", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR031367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR28601", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28601", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28601:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28601:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B1W5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1W5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGNYLSLWELVEEHVPLLERPEVKRILGETTVDLSLELRAEVVMLRTLLLEARSSQAPGSCPTSDPSSLLAPPPLLRDLVRQELRQLLQGLRRKAICEGRDQTQAWVRYSPRVLRFALEEPRCDVPEQKILQMKAGEPGCHRDLSIIKDQLDVSHIDEVAGHLRAALGATPPCPRALLEEECRTLEREIPILQRCLEEEYTGAPQPSEATLQPTLAELKEHKAAMQRELQAPLQPCWVSPSHRRWPLGSSSQGLRPLPCLHGAAEVSARPLQGCWPAPPLERCPKPRGPAATCRWGRKLRCSPRKRPASTPVSSGAPQAPT", "length": 322, "header": "tr|A0A287B1W5-1|A0A287B1W5_PIG Isoform 1 of Coiled-coil domain containing 24 OS=Sus scrofa OX=9823 GN=CCDC24 PE=4 SV=2 CANONICAL=A0A287B1W5-1" }, "isoforms": [ { "isoform_ac": "A0A287B1W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1W5/entry#A0A287B1W5-1", "sequence": { "sequence": "MPGNYLSLWELVEEHVPLLERPEVKRILGETTVDLSLELRAEVVMLRTLLLEARSSQAPGSCPTSDPSSLLAPPPLLRDLVRQELRQLLQGLRRKAICEGRDQTQAWVRYSPRVLRFALEEPRCDVPEQKILQMKAGEPGCHRDLSIIKDQLDVSHIDEVAGHLRAALGATPPCPRALLEEECRTLEREIPILQRCLEEEYTGAPQPSEATLQPTLAELKEHKAAMQRELQAPLQPCWVSPSHRRWPLGSSSQGLRPLPCLHGAAEVSARPLQGCWPAPPLERCPKPRGPAATCRWGRKLRCSPRKRPASTPVSSGAPQAPT", "length": 322, "header": "tr|A0A287B1W5-1|A0A287B1W5_PIG Isoform 1 of Coiled-coil domain containing 24 OS=Sus scrofa OX=9823 GN=CCDC24 PE=4 SV=2 CANONICAL=A0A287B1W5-1" }, "locus": { "chromosome": "6", "start_pos": 167305136, "end_pos": 167301901, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052765.2", "url": "https://www.ensembl.org/id/ENSSSCT00000052765.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050399.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050399.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1W5", "url": "https://www.uniprot.org/uniprotkb/A0A287B1W5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1W5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 322, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1W5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1W5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1Y4-1", "uniprot_ac": "A0A287B1Y4", "uniprot_id": "A0A287B1Y4_PIG", "mass": { "chemical_mass": 11826.0, "monoisotopic_mass": 11826.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A287B1Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y4", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y4", "locus": {} } ], "crossref": [ { "id": "A0A287B1Y4", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1Y4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000036825", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036825", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04980", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04980", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-173623", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-173623", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-198933", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-198933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2029481", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2029481", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2029482", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2029482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2029485", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2029485", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2168880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2454202", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2454202", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2730905", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2730905", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2871796", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2871796", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2871809", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2871809", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2871837", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2871837", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5690714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-977606", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-977606", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B1Y4", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWFLFPLSGARCAIQLTQSPASLAASLGDTVSITCRASQSINKWLAWYQQQPGKAPKLLIYSASTLQSGVPCGFKGSGSGTDFTLTISGLQAEDVATYYCQQHHSAPPTVL", "length": 111, "header": "tr|A0A287B1Y4-1|A0A287B1Y4_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A287B1Y4-1" }, "isoforms": [ { "isoform_ac": "A0A287B1Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y4/entry#A0A287B1Y4-1", "sequence": { "sequence": "MWFLFPLSGARCAIQLTQSPASLAASLGDTVSITCRASQSINKWLAWYQQQPGKAPKLLIYSASTLQSGVPCGFKGSGSGTDFTLTISGLQAEDVATYYCQQHHSAPPTVL", "length": 111, "header": "tr|A0A287B1Y4-1|A0A287B1Y4_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A287B1Y4-1" }, "locus": { "chromosome": "AEMK02000207.1", "start_pos": 31345, "end_pos": 31013, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052021.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052021.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050176.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050176.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y4", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-173623", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-173623", "resource": "Reactome", "description": "Classical antibody-mediated complement activation" }, { "id": "R-SSC-198933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-198933", "resource": "Reactome", "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" }, { "id": "R-SSC-202733", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202733", "resource": "Reactome", "description": "Cell surface interactions at the vascular wall" }, { "id": "R-SSC-2029481", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2029481", "resource": "Reactome", "description": "FCGR activation" }, { "id": "R-SSC-2029482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2029482", "resource": "Reactome", "description": "Regulation of actin dynamics for phagocytic cup formation" }, { "id": "R-SSC-2029485", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2029485", "resource": "Reactome", "description": "Role of phospholipids in phagocytosis" }, { "id": "R-SSC-2168880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2168880", "resource": "Reactome", "description": "Scavenging of heme from plasma" }, { "id": "R-SSC-2454202", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2454202", "resource": "Reactome", "description": "Fc epsilon receptor (FCERI) signaling" }, { "id": "R-SSC-2730905", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2730905", "resource": "Reactome", "description": "Role of LAT2/NTAL/LAB on calcium mobilization" }, { "id": "R-SSC-2871796", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2871796", "resource": "Reactome", "description": "FCERI mediated MAPK activation" }, { "id": "R-SSC-2871809", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2871809", "resource": "Reactome", "description": "FCERI mediated Ca+2 mobilization" }, { "id": "R-SSC-2871837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2871837", "resource": "Reactome", "description": "FCERI mediated NF-kB activation" }, { "id": "R-SSC-5690714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690714", "resource": "Reactome", "description": "CD22 mediated BCR regulation" }, { "id": "R-SSC-977606", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-977606", "resource": "Reactome", "description": "Regulation of Complement cascade" }, { "id": "R-SSC-983695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983695", "resource": "Reactome", "description": "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y4", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y4" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y4", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y4", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1Y4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 111, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1Y4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1Y4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B1Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y4" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 111, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1Y8-1", "uniprot_ac": "A0A287B1Y8", "uniprot_id": "A0A287B1Y8_PIG", "mass": { "chemical_mass": 7937.0, "monoisotopic_mass": 7937.0 }, "refseq": {}, "gene_names": [ { "name": "UQCC6", "type": "recommended", "evidence": [ { "id": "A0A287B1Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y8" } ] } ], "protein_names": [ { "name": "Ubiquinol-cytochrome c reductase complex assembly factor 6", "type": "synonym", "evidence": [ { "id": "A0A287B1Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UQCC6", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y8", "locus": { "chromosome": "5", "start_pos": 80510867, "end_pos": 80504281, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000056928", "url": "https://www.ensembl.org/id/ENSSSCG00000056928" } ] } } ], "crossref": [ { "id": "A0A287B1Y8", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1Y8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000032910", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000032910", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR027858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AVHRYYR", "url": "https://omabrowser.org/oma/group/AVHRYYR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287B1Y8", "url": "https://www.orthodb.org/?gene=A0A287B1Y8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28492", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28492", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28492:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28492:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14990", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14990", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B1Y8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAGVSWTSYLKMFAASLLAMCAGAEVVHRYYRPDLTIPEIPPKPGELKTELLGLKELQREPQDPTLPRTL", "length": 71, "header": "tr|A0A287B1Y8-1|A0A287B1Y8_PIG Isoform 1 of Ubiquinol-cytochrome c reductase complex assembly factor 6 OS=Sus scrofa OX=9823 GN=UQCC6 PE=3 SV=1 CANONICAL=A0A287B1Y8-1" }, "isoforms": [ { "isoform_ac": "A0A287B1Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y8/entry#A0A287B1Y8-1", "sequence": { "sequence": "MPAGVSWTSYLKMFAASLLAMCAGAEVVHRYYRPDLTIPEIPPKPGELKTELLGLKELQREPQDPTLPRTL", "length": 71, "header": "tr|A0A287B1Y8-1|A0A287B1Y8_PIG Isoform 1 of Ubiquinol-cytochrome c reductase complex assembly factor 6 OS=Sus scrofa OX=9823 GN=UQCC6 PE=3 SV=1 CANONICAL=A0A287B1Y8-1" }, "locus": { "chromosome": "5", "start_pos": 80509459, "end_pos": 80504715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092933.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092933.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078150.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078150.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PBT5-1", "protein_name": "C12orf73 homolog", "gene_name": "C12orf73", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPAGVPWSTYLKTLAASMLAMFAGAEVVHRYYRPDLSIPEVPPKPGELRTELLGLKARSKKAETSQH", "length": 67 }, "evidence": [ { "id": "A0A287B1Y8", "url": "https://omabrowser.org/oma/group/A0A287B1Y8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZZG3-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 6", "gene_name": "Uqcc6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGGVPWSVYLKMLSSSLLAMCAGAQVVHWYYRPDLTIPEIPPKPGELRTELLGLRERHRESQVSQQ", "length": 67 }, "evidence": [ { "id": "A0A287B1Y8", "url": "https://omabrowser.org/oma/group/A0A287B1Y8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7EXZ6-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 6", "gene_name": "uqcc6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPAGVSWPRYLRMFAASVLSMFAGAQVVHHYYRPDLSIPEIPPKPGELRTELLGLKERQMDSQKQ", "length": 65 }, "evidence": [ { "id": "A0A287B1Y8", "url": "https://omabrowser.org/oma/group/A0A287B1Y8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3N1R3-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 6", "gene_name": "UQCC6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPAGVSWSSYLKMFAASLLAMCAGAEVVHRYYRPDLRIPEIPPKPGELKTELLGLKERQQEHQNSTVPRTL", "length": 71 }, "evidence": [ { "id": "A0A287B1Y8", "url": "https://omabrowser.org/oma/group/A0A287B1Y8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q69YU5-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 6", "gene_name": "UQCC6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAGVPMSTYLKMFAASLLAMCAGAEVVHRYYRPDLTIPEIPPKRGELKTELLGLKERKHKPQVSQQEELK", "length": 71 }, "evidence": [ { "id": "A0A287B1Y8", "url": "https://omabrowser.org/oma/group/A0A287B1Y8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BTC1-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 6", "gene_name": "Uqcc6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGGVPWSAYLKMLSSSLLAMCAGAQVVHWYYRPDLTIPEIPPKPGELKTELLGLKERRHEPHVSQQ", "length": 67 }, "evidence": [ { "id": "A0A287B1Y8", "url": "https://omabrowser.org/oma/group/A0A287B1Y8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y8" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y8" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex III assembly", "id": "GO:0034551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034551", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Y8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Y8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1Y8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 71, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1Y8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1Y8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B1Z8-1", "uniprot_ac": "A0A287B1Z8", "uniprot_id": "A0A287B1Z8_PIG", "mass": { "chemical_mass": 35048.0, "monoisotopic_mass": 35048.0 }, "refseq": {}, "gene_names": [ { "name": "GASK1A", "type": "recommended", "evidence": [ { "id": "A0A287B1Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z8" } ] } ], "protein_names": [ { "name": "Golgi associated kinase 1A", "type": "synonym", "evidence": [ { "id": "A0A287B1Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Z8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GASK1A", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z8", "locus": {} } ], "crossref": [ { "id": "A0A287B1Z8", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B1Z8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011294", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011294", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15905:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15905:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15051", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15051", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B1Z8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHRARCTDPSAVGSGEVVGKARVPGHGQVLQVGFSAEGVLQNISPGLSQLCSQGLCGLIKRPGDLSEVLSFHVDRVLGLCRSLPAVARRFYNPLLPYRYTDGGARPVIWWAPDVQHLGDPDNDQNSLALGWLQYQALLARGCSRPGQDPCLDIHHAEWARLALFDFLLQVHDRLDRYCCGFEPEPSDPCVEERLREKCRNPRELRLVHILVRSSDPSHLVFIDNAGNLQHPEHKLNFRLLEGISGFPESVVKVLASGCLQNMLLKSLQMDPVFWESQGGQQGLQQVLQTLERRGQILLGHIRTHNLTLFGDEGP", "length": 315, "header": "tr|A0A287B1Z8-1|A0A287B1Z8_PIG Isoform 1 of Golgi associated kinase 1A OS=Sus scrofa OX=9823 GN=GASK1A PE=3 SV=1 CANONICAL=A0A287B1Z8-1" }, "isoforms": [ { "isoform_ac": "A0A287B1Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z8/entry#A0A287B1Z8-1", "sequence": { "sequence": "MAHRARCTDPSAVGSGEVVGKARVPGHGQVLQVGFSAEGVLQNISPGLSQLCSQGLCGLIKRPGDLSEVLSFHVDRVLGLCRSLPAVARRFYNPLLPYRYTDGGARPVIWWAPDVQHLGDPDNDQNSLALGWLQYQALLARGCSRPGQDPCLDIHHAEWARLALFDFLLQVHDRLDRYCCGFEPEPSDPCVEERLREKCRNPRELRLVHILVRSSDPSHLVFIDNAGNLQHPEHKLNFRLLEGISGFPESVVKVLASGCLQNMLLKSLQMDPVFWESQGGQQGLQQVLQTLERRGQILLGHIRTHNLTLFGDEGP", "length": 315, "header": "tr|A0A287B1Z8-1|A0A287B1Z8_PIG Isoform 1 of Golgi associated kinase 1A OS=Sus scrofa OX=9823 GN=GASK1A PE=3 SV=1 CANONICAL=A0A287B1Z8-1" }, "locus": { "chromosome": "13", "start_pos": 26473347, "end_pos": 26458324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046213.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046213.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050191.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050191.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Z8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1Z8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1Z8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B1Z8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 315, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B1Z8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B1Z8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 306, "end_pos": 308 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B204-1", "uniprot_ac": "A0A287B204", "uniprot_id": "A0A287B204_PIG", "mass": { "chemical_mass": 16717.0, "monoisotopic_mass": 16717.0 }, "refseq": { "ac": "NP_001421835", "name": "MORN repeat containing 2 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421835" }, "gene_names": [ { "name": "MORN2", "type": "recommended", "evidence": [ { "id": "A0A287B204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B204" } ] }, { "name": "MORN2", "type": "synonym", "evidence": [ { "id": "NP_001421835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421835" } ] } ], "protein_names": [ { "name": "MORN repeat containing 2 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001421835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421835" } ] }, { "name": "MORN repeat containing 2", "type": "synonym", "evidence": [ { "id": "A0A287B204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B204/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B204", "url": "https://www.uniprot.org/uniprotkb/A0A287B204" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MORN2", "url": "https://www.uniprot.org/uniprotkb/A0A287B204", "locus": { "chromosome": "3", "start_pos": 101452512, "end_pos": 101458862, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008480", "url": "https://www.ensembl.org/id/ENSSSCG00000008480" } ] } } ], "crossref": [ { "id": "A0A287B204", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B204", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008480", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008480", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100519139", "url": "https://www.ncbi.nlm.nih.gov/gene/100519139", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519139", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519139", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SXN3", "url": "https://www.orthodb.org/?gene=A0A4X1SXN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46917", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46917", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46917:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46917:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001421835", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421835", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B204", "url": "https://www.uniprot.org/uniprotkb/A0A287B204", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B204-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B204-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SXN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SXN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4S8", "url": "https://www.uniprot.org/uniprotkb/F1S4S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4S8-1", "url": "https://www.uniprot.org/uniprotkb/F1S4S8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAQGESQSPENLSSTSVSTPEVFKINFIFPNGDKYDGDCTRTSSGVFERNGIGIHTTPNGIVYTGSWKDDKMNGFGRLEHFSGAVYEGHFKDNMFHGLGTYTFPTGAKYTGNFNENRVEGEGQYTDIQGLEWCGNFHFKAAPGLRLKLHM", "length": 151, "header": "tr|A0A287B204-1|A0A287B204_PIG Isoform 1 of MORN repeat containing 2 OS=Sus scrofa OX=9823 GN=MORN2 PE=4 SV=2 CANONICAL=A0A287B204-1" }, "isoforms": [ { "isoform_ac": "A0A287B204-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B204/entry#A0A287B204-1", "sequence": { "sequence": "MAAQGESQSPENLSSTSVSTPEVFKINFIFPNGDKYDGDCTRTSSGVFERNGIGIHTTPNGIVYTGSWKDDKMNGFGRLEHFSGAVYEGHFKDNMFHGLGTYTFPTGAKYTGNFNENRVEGEGQYTDIQGLEWCGNFHFKAAPGLRLKLHM", "length": 151, "header": "tr|A0A287B204-1|A0A287B204_PIG Isoform 1 of MORN repeat containing 2 OS=Sus scrofa OX=9823 GN=MORN2 PE=4 SV=2 CANONICAL=A0A287B204-1" }, "locus": { "chromosome": "3", "start_pos": 101458789, "end_pos": 101452795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038153.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038153.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050196.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050196.2" } ] } }, { "isoform_ac": "A0A4X1SXN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B204/entry#A0A4X1SXN3-1", "sequence": { "sequence": "MNGFGRLEHFSGAVYEGHFKDNMFHGLGTYTFPTGAKYTGNFNENRVEGEGQYTDIQGLEWCGNFHFKAAPGLRLKLHM", "length": 79, "header": "tr|A0A4X1SXN3-1|A0A4X1SXN3_PIG Computationally mapped isoform of MORN repeat containing 2 OS=Sus scrofa OX=9823 GN=MORN2 PE=4 SV=1 CANONICAL=A0A287B204-1" }, "locus": { "chromosome": "3", "start_pos": 101454029, "end_pos": 101452795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081472.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081472.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067413.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067413.2" } ] } }, { "isoform_ac": "F1S4S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B204/entry#F1S4S8-1", "sequence": { "sequence": "MGLSTQEAGKMTRVEGEGQYTDIQGLEWCGNFHFKAAPGLRLKLHM", "length": 46, "header": "tr|F1S4S8-1|A0A287B204_PIG Computationally mapped isoform of MORN repeat containing 2 OS=Sus scrofa OX=9823 GN=MORN2 PE=4 SV=3 CANONICAL=A0A287B204-1" }, "locus": { "chromosome": "3", "start_pos": 101454753, "end_pos": 101452795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009282.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009282.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009047.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009047.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S4S8", "url": "https://www.uniprot.org/uniprotkb/F1S4S8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519139", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519139", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B204-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 151, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B204-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B204" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B215-1", "uniprot_ac": "A0A287B215", "uniprot_id": "A0A287B215_PIG", "mass": { "chemical_mass": 59090.0, "monoisotopic_mass": 59090.0 }, "refseq": {}, "gene_names": [ { "name": "CNBD1", "type": "recommended", "evidence": [ { "id": "A0A287B215", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B215" } ] } ], "protein_names": [ { "name": "Cyclic nucleotide binding domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A287B215", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B215/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B215", "url": "https://www.uniprot.org/uniprotkb/A0A287B215" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CNBD1", "url": "https://www.uniprot.org/uniprotkb/A0A287B215", "locus": { "chromosome": "4", "start_pos": 49403429, "end_pos": 49970329, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036161", "url": "https://www.ensembl.org/id/ENSSSCG00000036161" } ] } } ], "crossref": [ { "id": "A0A287B215", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B215", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000036161", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036161", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00038", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00038", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23011", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23011", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23011:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23011:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B215", "url": "https://www.uniprot.org/uniprotkb/A0A287B215", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B215-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B215-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPMSSLPAAILSHMIAISNVPPPPLCRIPSLHMSKNIDYSQLNALCHMRGLQHSRTNILSAHNAFIKQYPKIFIKKKTRLPKIVKEEVKRKTAEGAEEDKPQQPDDSHNIAVHVKRARGGRTLYGPKKSEEKLVEFMAILKVLPIHRTPSEHNAVWKMLKTIPDLTSQLSDEHLKILSKNVISETWIKGSTVIGNDGFYIILKGLARPQTQVYKNLIEDNESTTSFIPQSFHNFVFSEDFKNSELTEKQLIPCDSMLGQWSTFGTLDITAQIESEAKEYAVVTEEDCEILKIPAKNYAKLKSEKTKLENKHKVTLIRKCPYYEEWPTLSIYELVTLIKWKKFPPGHVIVESGNIISFVAYINSGYCKIYRNIVGLSKTQSKRVKKNQKRVYMGRLKEKESFGEISVLLQVPFTCTIITGKDVEMAIIEDKDLFELDAVTRQLMLQTAKPTFGHLTDEDVKNEYLRKEQKREWRSFKDKTMKNSLYYNGIIPGFGKWNHSCTSLRRHLKDTLVKY", "length": 514, "header": "tr|A0A287B215-1|A0A287B215_PIG Isoform 1 of Cyclic nucleotide binding domain containing 1 OS=Sus scrofa OX=9823 GN=CNBD1 PE=4 SV=3 CANONICAL=A0A287B215-1" }, "isoforms": [ { "isoform_ac": "A0A287B215-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B215/entry#A0A287B215-1", "sequence": { "sequence": "MPMSSLPAAILSHMIAISNVPPPPLCRIPSLHMSKNIDYSQLNALCHMRGLQHSRTNILSAHNAFIKQYPKIFIKKKTRLPKIVKEEVKRKTAEGAEEDKPQQPDDSHNIAVHVKRARGGRTLYGPKKSEEKLVEFMAILKVLPIHRTPSEHNAVWKMLKTIPDLTSQLSDEHLKILSKNVISETWIKGSTVIGNDGFYIILKGLARPQTQVYKNLIEDNESTTSFIPQSFHNFVFSEDFKNSELTEKQLIPCDSMLGQWSTFGTLDITAQIESEAKEYAVVTEEDCEILKIPAKNYAKLKSEKTKLENKHKVTLIRKCPYYEEWPTLSIYELVTLIKWKKFPPGHVIVESGNIISFVAYINSGYCKIYRNIVGLSKTQSKRVKKNQKRVYMGRLKEKESFGEISVLLQVPFTCTIITGKDVEMAIIEDKDLFELDAVTRQLMLQTAKPTFGHLTDEDVKNEYLRKEQKREWRSFKDKTMKNSLYYNGIIPGFGKWNHSCTSLRRHLKDTLVKY", "length": 514, "header": "tr|A0A287B215-1|A0A287B215_PIG Isoform 1 of Cyclic nucleotide binding domain containing 1 OS=Sus scrofa OX=9823 GN=CNBD1 PE=4 SV=3 CANONICAL=A0A287B215-1" }, "locus": { "chromosome": "4", "start_pos": 49970278, "end_pos": 49403571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046700.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046700.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050207.3", "url": "https://www.ensembl.org/id/ENSSSCP00000050207.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B215", "url": "https://www.uniprot.org/uniprotkb/A0A287B215" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B215-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 514, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B215-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B215" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B215", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B215" }, { "id": "PS50042", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50042" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclic nucleotide-binding", "eco_id": "ECO_0000259", "start_pos": 321, "end_pos": 435, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 }, { "start_pos": 497, "end_pos": 499 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B223-1", "uniprot_ac": "A0A287B223", "uniprot_id": "A0A287B223_PIG", "mass": { "chemical_mass": 32772.0, "monoisotopic_mass": 32772.0 }, "refseq": { "ac": "XP_013843042", "name": "protein Largen isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013843042" }, "gene_names": [ { "name": "PRR16", "type": "recommended", "evidence": [ { "id": "A0A287B223", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B223" } ] }, { "name": "PRR16", "type": "synonym", "evidence": [ { "id": "XP_013843042", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013843042" } ] } ], "protein_names": [ { "name": "Proline rich 16", "type": "synonym", "evidence": [ { "id": "A0A287B223", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B223/entry#names_and_taxonomy" } ] }, { "name": "protein Largen isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013843042", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013843042" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B223", "url": "https://www.uniprot.org/uniprotkb/A0A287B223" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PRR16", "url": "https://www.uniprot.org/uniprotkb/A0A287B223", "locus": { "chromosome": "2", "start_pos": 124463885, "end_pos": 124199508, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000039760", "url": "https://www.ensembl.org/id/ENSSSCG00000039760" } ] } } ], "crossref": [ { "id": "ENSSSCG00000039760", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000039760", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100524363", "url": "https://www.ncbi.nlm.nih.gov/gene/100524363", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524363", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524363", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PGKLPHQ", "url": "https://omabrowser.org/oma/group/PGKLPHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287B223", "url": "https://www.orthodb.org/?gene=A0A287B223", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15917", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15917", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15917:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15917:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15252", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15252", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013843042", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013843042", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B223", "url": "https://www.uniprot.org/uniprotkb/A0A287B223", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B223-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B223-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAKSKGTPASSSPAEGPPAASKTKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSGTTASSIEKIKVQANAPLIKPPAHPSAILTVLRKPNPPPPPPRLTPVKCEDPQRVVPTVNPVKTNGTLLRNGGFPGAPNKIPNGDICCKPGSIVDKAPVQPLMHRPEKDRCPQAGPRERVRFNEKVQYHGYCPDCDTRYNIKNREVHLHSEPVHPPGKLPPQGPHHPPPPHLPPFPLENGGLGISHSNSFPPLRPATVPPPTAPKPQKTILRKSTTTTV", "length": 304, "header": "tr|A0A287B223-1|A0A287B223_PIG Isoform 1 of Proline rich 16 OS=Sus scrofa OX=9823 GN=PRR16 PE=4 SV=1 CANONICAL=A0A287B223-1" }, "isoforms": [ { "isoform_ac": "A0A287B223-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B223/entry#A0A287B223-1", "sequence": { "sequence": "MSAKSKGTPASSSPAEGPPAASKTKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSGTTASSIEKIKVQANAPLIKPPAHPSAILTVLRKPNPPPPPPRLTPVKCEDPQRVVPTVNPVKTNGTLLRNGGFPGAPNKIPNGDICCKPGSIVDKAPVQPLMHRPEKDRCPQAGPRERVRFNEKVQYHGYCPDCDTRYNIKNREVHLHSEPVHPPGKLPPQGPHHPPPPHLPPFPLENGGLGISHSNSFPPLRPATVPPPTAPKPQKTILRKSTTTTV", "length": 304, "header": "tr|A0A287B223-1|A0A287B223_PIG Isoform 1 of Proline rich 16 OS=Sus scrofa OX=9823 GN=PRR16 PE=4 SV=1 CANONICAL=A0A287B223-1" }, "locus": { "chromosome": "2", "start_pos": 124365691, "end_pos": 124199734, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050087.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050087.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051281.1", "url": "https://www.ensembl.org/id/ENSSSCP00000051281.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 287, "start_aa": "Thr", "end_pos": 287, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr287", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B223", "url": "https://www.uniprot.org/uniprotkb/A0A287B223" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524363", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524363", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A7G3-1", "protein_name": "Proline rich 16", "gene_name": "Prr16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAKSKGNPSSSSAAEGPPAASKTKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSGTTASSIEKIKEQANAPLIKPPAHPSAILTVLRKPNPPPPPPRLTPVRCEEPQKAAPTANPLKTNGTLLRNGGLPGRPNKIPNGDICCVPNSNLDKAPLQSLMHRPEKDRSPQAGPRERVRFNEKVQYHGYCPDCETRYNIKNREVHLHSEPVHPPGKLPHYGPVLPPPPHLPTFPLENGGLGISHSNSFPPHTPATVPPPPTAPKPQKTILRKSTTTTV", "length": 305 }, "evidence": [ { "id": "A0A287B223", "url": "https://omabrowser.org/oma/group/A0A287B223/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9SPA5-1", "protein_name": "Proline rich 16", "gene_name": "PRR16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSAKSKGTPSSSSPAEGPPAASKTKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSGTTASSIEKIKVQANAPLIKPPAHPSAILTVLRKPNPPAPPPRLTPVKCEDSQRVVPTVNPVKTNGTLLRNGGFPGAPTKIPNGDIYCKPSSNLDKAPGQPLMHRPEKDRCPQAGPRERVRFNEKVQYHGYCPDCDTRYHVKNREVHLHSEPVHPPGKLPPQGPPHPLPPHLPPFPLENGGLGISHSNSFPPLRPATVPPPIAPKPQKTILRKSTTTTV", "length": 304 }, "evidence": [ { "id": "A0A287B223", "url": "https://omabrowser.org/oma/group/A0A287B223/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A3KMN5-1", "protein_name": "Protein Largen", "gene_name": "Prr16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAKSKGNPSSSSAAEGPPAASKTKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSGTTASSIEKIKEQANAPLIKPPAHPSAILTVLRKPNPPPPPPRLTPVRCEEPQRVVPTANPVKTNGTLLRNGGLAGRPNKIPNGDICCIPNSNLDKAPLQSLMHRPEKDRSPQAGPRERVRFNEKVQYHGYCPDCESRYNIKNREVHLHSEPVHPPGKIPHQGPLLHPPPHLPNFPLENGGLGISHSNSFPPPTPATVPPPAAPKPQKTILRKSTTTTV", "length": 304 }, "evidence": [ { "id": "A0A287B223", "url": "https://omabrowser.org/oma/group/A0A287B223/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BW34-1", "protein_name": "Proline rich 16", "gene_name": "PRR16", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAQSKGTASSSSSPSEGPPAASKAKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSSTTASSLEKVKVRGSTPLIKNPVHPSAILTVLRKPNPPPPPPRLTPVKCDKQLRPPPSANPVKTNGTLLRNGPSRIPNGDLCCIPNSNLDSVAIPPLMHRPEKERCPQAGARERVRFSEKVQYHGYCPDCDVRYNIKNREVHLHSEPAHLLGALPHQCPPLPPPPPPLPPFPLENGGLGISSSNSFPPPRPVTVPPQTAPKPQKTILRKSTTTTV", "length": 301 }, "evidence": [ { "id": "A0A287B223", "url": "https://omabrowser.org/oma/group/A0A287B223/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q569H4-1", "protein_name": "Protein Largen", "gene_name": "PRR16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAKSKGNPSSSCPAEGPPAASKTKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSGTTASSLEKIKVQANAPLIKPPAHPSAILTVLRKPNPPPPPPRLTPVKCEDPKRVVPTANPVKTNGTLLRNGGLPGGPNKIPNGDICCIPNSNLDKAPVQLLMHRPEKDRCPQAGPRERVRFNEKVQYHGYCPDCDTRYNIKNREVHLHSEPVHPPGKIPHQGPPLPPTPHLPPFPLENGGMGISHSNSFPPIRPATVPPPTAPKPQKTILRKSTTTTV", "length": 304 }, "evidence": [ { "id": "A0A287B223", "url": "https://omabrowser.org/oma/group/A0A287B223/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "A0A287B223", "url": "https://www.uniprot.org/uniprotkb/A0A287B223" } ], "pmid": "" }, { "name": "positive regulation of cell size", "id": "GO:0045793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045793", "evidence": [ { "database": "UniProtKB", "id": "A0A287B223", "url": "https://www.uniprot.org/uniprotkb/A0A287B223" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 287 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B224-1", "uniprot_ac": "A0A287B224", "uniprot_id": "A0A287B224_PIG", "mass": { "chemical_mass": 58384.0, "monoisotopic_mass": 58384.0 }, "refseq": { "ac": "XP_020922331", "name": "polymeric immunoglobulin receptor-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922331" }, "gene_names": [ { "name": "LOC100515852", "type": "recommended", "evidence": [ { "id": "A0A287B224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B224" } ] }, { "name": "LOC100515852", "type": "synonym", "evidence": [ { "id": "XP_020922331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922331" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A287B224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B224/entry#names_and_taxonomy" } ] }, { "name": "polymeric immunoglobulin receptor-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020922331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922331" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B224", "url": "https://www.uniprot.org/uniprotkb/A0A287B224" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100515852", "url": "https://www.uniprot.org/uniprotkb/A0A287B224", "locus": {} } ], "crossref": [ { "id": "A0A287B224", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B224", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017235", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017235", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515852", "url": "https://www.ncbi.nlm.nih.gov/gene/100515852", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11860:SF101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11860:SF101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-198933", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-198933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020922331", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922331", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B224", "url": "https://www.uniprot.org/uniprotkb/A0A287B224", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B224-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B224-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGRAEWLLWALLLPFLEGSSPVTGPKAVRGQERGSLAVQCRYTPGWESHGKWWCRGADWGNCKILVQTTASEPEVKRDRVSIRDDRENRTFTVTTEELRLDDAGIYWCGIARVGTDHAEQVSVTVDPGSSPVTGPKAVRGQERGSLAVQCRYTPGWESHGKWWCRGADWGNCKILVQTTASEPEVKRDRVSIRDDRENRTFTVTTEELRLDDAGIYWCGIARVGTDHAEQVSVTVDPGSSPVTGPKAVRGQERGSLAVQCRYTPGWESHGKWWCRGADWGNCKILVQTTASEPEVKRDRVSIRDDRENRTFTVTTEELRLDDAGIYWCGIARVGTDHAEQVSVTVDPGSSPVTGPKAVRGQERGSLAVQCRYTPGWESHGKWWCRGADWDSCKILVQTTASEPEVKRDRVSIRDDRENRTFTVTTEELRLDDAGVYWCGIERVGHDHGTQVRVTVDPAPVTSGDDSLNMTSHGPNGRSLLRSIHFLLLVFLKMPLFLGMLSAVLWVHRPQGSSRWETKSAL", "length": 522, "header": "tr|A0A287B224-1|A0A287B224_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100515852 PE=3 SV=2 CANONICAL=A0A287B224-1" }, "isoforms": [ { "isoform_ac": "A0A287B224-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B224/entry#A0A287B224-1", "sequence": { "sequence": "MRGRAEWLLWALLLPFLEGSSPVTGPKAVRGQERGSLAVQCRYTPGWESHGKWWCRGADWGNCKILVQTTASEPEVKRDRVSIRDDRENRTFTVTTEELRLDDAGIYWCGIARVGTDHAEQVSVTVDPGSSPVTGPKAVRGQERGSLAVQCRYTPGWESHGKWWCRGADWGNCKILVQTTASEPEVKRDRVSIRDDRENRTFTVTTEELRLDDAGIYWCGIARVGTDHAEQVSVTVDPGSSPVTGPKAVRGQERGSLAVQCRYTPGWESHGKWWCRGADWGNCKILVQTTASEPEVKRDRVSIRDDRENRTFTVTTEELRLDDAGIYWCGIARVGTDHAEQVSVTVDPGSSPVTGPKAVRGQERGSLAVQCRYTPGWESHGKWWCRGADWDSCKILVQTTASEPEVKRDRVSIRDDRENRTFTVTTEELRLDDAGVYWCGIERVGHDHGTQVRVTVDPAPVTSGDDSLNMTSHGPNGRSLLRSIHFLLLVFLKMPLFLGMLSAVLWVHRPQGSSRWETKSAL", "length": 522, "header": "tr|A0A287B224-1|A0A287B224_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100515852 PE=3 SV=2 CANONICAL=A0A287B224-1" }, "locus": { "chromosome": "12", "start_pos": 6615768, "end_pos": 6597340, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035140.3", "url": "https://www.ensembl.org/id/ENSSSCT00000035140.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050455.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050455.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B224", "url": "https://www.uniprot.org/uniprotkb/A0A287B224" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-198933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-198933", "resource": "Reactome", "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A287B224", "url": "https://www.uniprot.org/uniprotkb/A0A287B224" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A287B224", "url": "https://www.uniprot.org/uniprotkb/A0A287B224" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response-activating signaling pathway", "id": "GO:0002757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002757", "evidence": [ { "database": "UniProtKB", "id": "A0A287B224", "url": "https://www.uniprot.org/uniprotkb/A0A287B224" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B224-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 522, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B224-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B224" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B224" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 125, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 309, "end_pos": 311 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B245-1", "uniprot_ac": "A0A287B245", "uniprot_id": "A0A287B245_PIG", "mass": { "chemical_mass": 40670.0, "monoisotopic_mass": 40670.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100737676", "type": "recommended", "evidence": [ { "id": "A0A287B245", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B245" } ] } ], "protein_names": [ { "name": "SH2 domain containing 4A", "type": "recommended", "evidence": [ { "id": "A0A287B245", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B245/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B245", "url": "https://www.uniprot.org/uniprotkb/A0A287B245" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100737676", "url": "https://www.uniprot.org/uniprotkb/A0A287B245", "locus": {} } ], "crossref": [ { "id": "A0A287B245", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B245", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000038135", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000038135", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "PTHR14388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14388:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14388:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A287B245", "url": "https://www.uniprot.org/uniprotkb/A0A287B245", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B245-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B245-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKQILSKMYIDPDLLAELSEEQKQILFFKMREEQVRRWKEREEAMEKKESLPVQPRPKKDNGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCEEILAERARLKAEQEAAELRTSQSRESTGSLKTKSQASDVQAPGDKESRVGKKAAEEGGQGRGCGPAPSPEEQKTPSPSSSSRNIQQMLADSISRMKEYGFLQKKESVKKTQDEEIKQIDEERTKQIYKNWKEDSEWQASLRKSKAADERRRSLAKQAREDYKRLSQRGRGSEGPQSPPGGPQKPRRPPLPPKPQFLSPTGHPHRPLRNQGVMRTESSSAQEDIVRWFREEQLPLRAGYLATSDSIAPWFHGECLAPQGAPI", "length": 356, "header": "tr|A0A287B245-1|A0A287B245_PIG Isoform 1 of SH2 domain containing 4A OS=Sus scrofa OX=9823 GN=LOC100737676 PE=4 SV=2 CANONICAL=A0A287B245-1" }, "isoforms": [ { "isoform_ac": "A0A287B245-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B245/entry#A0A287B245-1", "sequence": { "sequence": "MLKQILSKMYIDPDLLAELSEEQKQILFFKMREEQVRRWKEREEAMEKKESLPVQPRPKKDNGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCEEILAERARLKAEQEAAELRTSQSRESTGSLKTKSQASDVQAPGDKESRVGKKAAEEGGQGRGCGPAPSPEEQKTPSPSSSSRNIQQMLADSISRMKEYGFLQKKESVKKTQDEEIKQIDEERTKQIYKNWKEDSEWQASLRKSKAADERRRSLAKQAREDYKRLSQRGRGSEGPQSPPGGPQKPRRPPLPPKPQFLSPTGHPHRPLRNQGVMRTESSSAQEDIVRWFREEQLPLRAGYLATSDSIAPWFHGECLAPQGAPI", "length": 356, "header": "tr|A0A287B245-1|A0A287B245_PIG Isoform 1 of SH2 domain containing 4A OS=Sus scrofa OX=9823 GN=LOC100737676 PE=4 SV=2 CANONICAL=A0A287B245-1" }, "locus": { "chromosome": "AEMK02000563.1", "start_pos": 65209, "end_pos": 15521, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047772.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047772.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050319.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050319.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B245", "url": "https://www.uniprot.org/uniprotkb/A0A287B245" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A287B245", "url": "https://www.uniprot.org/uniprotkb/A0A287B245" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A287B245", "url": "https://www.uniprot.org/uniprotkb/A0A287B245" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B245-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 356, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B245-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B245" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B2B8-1", "uniprot_ac": "A0A287B2B8", "uniprot_id": "A0A287B2B8_PIG", "mass": { "chemical_mass": 20427.0, "monoisotopic_mass": 20427.0 }, "refseq": { "ac": "XP_020922222", "name": "matrix remodeling associated 7 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922222" }, "gene_names": [ { "name": "MXRA7", "type": "recommended", "evidence": [ { "id": "A0A287B2B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2B8" } ] }, { "name": "MXRA7", "type": "synonym", "evidence": [ { "id": "XP_020922222", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922222" } ] } ], "protein_names": [ { "name": "Matrix remodeling associated 7", "type": "synonym", "evidence": [ { "id": "A0A287B2B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2B8/entry#names_and_taxonomy" } ] }, { "name": "matrix remodeling associated 7 isoform 1", "type": "synonym", "evidence": [ { "id": "XP_020922222", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922222" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B2B8", "url": "https://www.uniprot.org/uniprotkb/A0A287B2B8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MXRA7", "url": "https://www.uniprot.org/uniprotkb/A0A287B2B8", "locus": {} } ], "crossref": [ { "id": "A0A287B2B8", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B2B8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000037376", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037376", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100622193", "url": "https://www.ncbi.nlm.nih.gov/gene/100622193", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NGERPFF", "url": "https://omabrowser.org/oma/group/NGERPFF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287B2B8", "url": "https://www.orthodb.org/?gene=A0A287B2B8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21845:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21845:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020922222", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922222", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B2B8", "url": "https://www.uniprot.org/uniprotkb/A0A287B2B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QCH6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QCH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAPAELLAALPALATALALLLAWLLLRRGAAASSNPAGAPPEPAPPAEAGGTPEPPGPCAAEPAAAPEGPGEPALPDKPTAAPAEAAAAAAEEEEQAAEERQEEEQELRGEEEPPQAGPAEEDGGEAFAFRYSPGKLRGNQYKKMMTKEELEEEQRVQKEQLAAIFKLMKDNEATFGEMSAGDVQEQLRLYDM", "length": 194, "header": "tr|A0A287B2B8-1|A0A287B2B8_PIG Isoform 1 of Matrix remodeling associated 7 OS=Sus scrofa OX=9823 GN=MXRA7 PE=1 SV=1 CANONICAL=A0A287B2B8-1" }, "isoforms": [ { "isoform_ac": "A0A287B2B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2B8/entry#A0A287B2B8-1", "sequence": { "sequence": "MEAPAELLAALPALATALALLLAWLLLRRGAAASSNPAGAPPEPAPPAEAGGTPEPPGPCAAEPAAAPEGPGEPALPDKPTAAPAEAAAAAAEEEEQAAEERQEEEQELRGEEEPPQAGPAEEDGGEAFAFRYSPGKLRGNQYKKMMTKEELEEEQRVQKEQLAAIFKLMKDNEATFGEMSAGDVQEQLRLYDM", "length": 194, "header": "tr|A0A287B2B8-1|A0A287B2B8_PIG Isoform 1 of Matrix remodeling associated 7 OS=Sus scrofa OX=9823 GN=MXRA7 PE=1 SV=1 CANONICAL=A0A287B2B8-1" }, "locus": { "chromosome": "12", "start_pos": 4858863, "end_pos": 4822329, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105632.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105632.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076484.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076484.1" } ] } }, { "isoform_ac": "A0A5G2QCH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2B8/entry#A0A5G2QCH6-1", "sequence": { "sequence": "MMTKEELEEEQRIELTSDLTSL", "length": 22, "header": "tr|A0A5G2QCH6-1|A0A287B2B8_PIG Computationally mapped isoform of Matrix remodeling associated 7 OS=Sus scrofa OX=9823 GN=MXRA7 PE=1 SV=1 CANONICAL=A0A287B2B8-1" }, "locus": { "chromosome": "12", "start_pos": 4842914, "end_pos": 4841924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079504.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079504.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061810.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061810.1" } ] } }, { "isoform_ac": "A0A8W4F8Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2B8/entry#A0A8W4F8Y2-1", "sequence": { "sequence": "MMTKEELEEEQRTEE", "length": 15, "header": "tr|A0A8W4F8Y2-1|A0A287B2B8_PIG Computationally mapped isoform of Matrix remodeling associated 7 OS=Sus scrofa OX=9823 GN=MXRA7 PE=1 SV=1 CANONICAL=A0A287B2B8-1" }, "locus": { "chromosome": "12", "start_pos": 4855968, "end_pos": 4841924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093868.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093868.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075843.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075843.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Thr", "end_pos": 53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QCH6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCH6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M2I8-1", "protein_name": "Matrix remodeling associated 7", "gene_name": "Mxra7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESPLELLAALPALITALALLFAWLLLRRGAARAPESTTRAGDPGAPAPPEPPEPCALEPPSVGPCQFERLAEPEEEEPEAEGRQDEDSDSEMGPPTEEPEEEAGAAFSFKYSPGQLRGSQYKKMMTKEELEEEQSMLPEALTRPPITRLPISPDICLLSHPCMQAQLEGASPDHTSVLRLMLGLAEAAQAGFALLSLGSGEKIATRQNWTQPNLGERP", "length": 219 }, "evidence": [ { "id": "A0A287B2B8", "url": "https://omabrowser.org/oma/group/A0A287B2B8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P84157-1", "protein_name": "Matrix-remodeling-associated protein 7", "gene_name": "MXRA7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKEQLAAIFKLMKDNKETFGEMSDGDVQEQLRLYDM", "length": 204 }, "evidence": [ { "id": "A0A287B2B8", "url": "https://omabrowser.org/oma/group/A0A287B2B8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZH7-1", "protein_name": "Matrix-remodeling-associated protein 7", "gene_name": "Mxra7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESPVELLAALPALVTALALLLAWLLLRRGAARVPAPESTASDEAPGAPAPPEPPESCAPEPAPEGPSQSERVAEPEESEAEEPAAEGRQDEDSDSEMGPPTEEPEEEDGAAFSFKYSPGQLRGSQYKKMMTKEELEEEHRVQKEQLAAIFKLMKDNKDTFGEMSDGDMQEQLRLYDM", "length": 178 }, "evidence": [ { "id": "A0A287B2B8", "url": "https://omabrowser.org/oma/group/A0A287B2B8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "megakaryocyte differentiation", "id": "GO:0030219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030219", "evidence": [ { "database": "UniProtKB", "id": "A0A287B2B8", "url": "https://www.uniprot.org/uniprotkb/A0A287B2B8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B2B8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 194, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B2B8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B2B8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B2B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2B8" }, { "id": "PF25473", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25473" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Matrix-remodeling-associated protein 7 helical", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 193, "start_aa": "Tyr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 53 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B2C2-1", "uniprot_ac": "A0A287B2C2", "uniprot_id": "A0A287B2C2_PIG", "mass": { "chemical_mass": 23234.0, "monoisotopic_mass": 23234.0 }, "refseq": {}, "gene_names": [ { "name": "CUTAL", "type": "recommended", "evidence": [ { "id": "A0A287B2C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2C2" } ] } ], "protein_names": [ { "name": "CutA divalent cation tolerance like", "type": "synonym", "evidence": [ { "id": "A0A287B2C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2C2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B2C2", "url": "https://www.uniprot.org/uniprotkb/A0A287B2C2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CUTAL", "url": "https://www.uniprot.org/uniprotkb/A0A287B2C2", "locus": {} } ], "crossref": [ { "id": "A0A287B2C2", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B2C2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000039972", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000039972", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23419:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23419:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B2C2", "url": "https://www.uniprot.org/uniprotkb/A0A287B2C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2C2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVLLPGQRRFKRRRRVMALEDEMKILDNLEEGVSKGGVGRPLGVSQATTRILKQNEKAIRASIFRHLLQILTASFLTYPMLKTLSLQLLSLVTGSYVSGTYSIVFVNCPNEQIARDIARAILDKKLAASVNILPKASSLYFWNGEIEEATEILLIIKTKTSKVRLLSSYIRLVHPFEIPEIFSLPMDQGDVHYLKWLEEGMEEE", "length": 205, "header": "tr|A0A287B2C2-1|A0A287B2C2_PIG Isoform 1 of CutA divalent cation tolerance like OS=Sus scrofa OX=9823 GN=CUTAL PE=3 SV=1 CANONICAL=A0A287B2C2-1" }, "isoforms": [ { "isoform_ac": "A0A287B2C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2C2/entry#A0A287B2C2-1", "sequence": { "sequence": "MGVLLPGQRRFKRRRRVMALEDEMKILDNLEEGVSKGGVGRPLGVSQATTRILKQNEKAIRASIFRHLLQILTASFLTYPMLKTLSLQLLSLVTGSYVSGTYSIVFVNCPNEQIARDIARAILDKKLAASVNILPKASSLYFWNGEIEEATEILLIIKTKTSKVRLLSSYIRLVHPFEIPEIFSLPMDQGDVHYLKWLEEGMEEE", "length": 205, "header": "tr|A0A287B2C2-1|A0A287B2C2_PIG Isoform 1 of CutA divalent cation tolerance like OS=Sus scrofa OX=9823 GN=CUTAL PE=3 SV=1 CANONICAL=A0A287B2C2-1" }, "locus": { "chromosome": "1", "start_pos": 260894256, "end_pos": 260869127, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062574.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062574.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050248.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050248.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B2C2", "url": "https://www.uniprot.org/uniprotkb/A0A287B2C2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A287B2C2", "url": "https://www.uniprot.org/uniprotkb/A0A287B2C2" } ], "pmid": "" }, { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "A0A287B2C2", "url": "https://www.uniprot.org/uniprotkb/A0A287B2C2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to metal ion", "id": "GO:0010038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010038", "evidence": [ { "database": "UniProtKB", "id": "A0A287B2C2", "url": "https://www.uniprot.org/uniprotkb/A0A287B2C2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B2C2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 205, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B2C2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B2C2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B2C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2C2" }, { "id": "PF04218", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04218" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH psq-type", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 64, "start_aa": "Lys", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A287B2E0-1", "uniprot_ac": "A0A287B2E0", "uniprot_id": "A0A287B2E0_PIG", "mass": { "chemical_mass": 44547.0, "monoisotopic_mass": 44547.0 }, "refseq": {}, "gene_names": [ { "name": "SLFNL1", "type": "recommended", "evidence": [ { "id": "A0A287B2E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2E0" } ] } ], "protein_names": [ { "name": "Schlafen like 1", "type": "synonym", "evidence": [ { "id": "A0A287B2E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2E0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287B2E0", "url": "https://www.uniprot.org/uniprotkb/A0A287B2E0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLFNL1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2E0", "locus": { "chromosome": "6", "start_pos": 170199630, "end_pos": 170194822, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003972", "url": "https://www.ensembl.org/id/ENSSSCG00000003972" } ] } } ], "crossref": [ { "id": "A0A287B2E0", "url": "https://alphafold.ebi.ac.uk/entry/A0A287B2E0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003972", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003972", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12155:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12155:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B2E0", "url": "https://www.uniprot.org/uniprotkb/A0A287B2E0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2E0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SF79", "url": "https://www.uniprot.org/uniprotkb/F1SF79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SF79-1", "url": "https://www.uniprot.org/uniprotkb/F1SF79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ETPRKTSLTQEQEPLMEPPGRQPLGELPAEASPPEDAGAEAAPSRRLLYVGHLNPQLPVPVLACLLRDALERLELPVAREHIEVVRRPREAFALVQVATHEDTLASLPWRLLAASGRHQIIQELVARGKELVLEEGWEPASRRAQENDGGPSPSPSPGPSPRSRFPPAWPPGTPPARAATPGQQSPPGCPRAAYSDSALVRQEILGQERLFQGALLGCETRNVEFKRGSGGYLSRAFKHHLRCYVCAFLNGEGGSLLVGVEDGGRVQGVRCSPRDEDRVRLLVDSVLQGFKPQVFPDAYRLEFIPVVGASATGAPLKVIRLSVQAPKAQAEPLLYETDKGEVFLRRDGSIQGPLSVHAIQEWCRQKWTAELRKLEERLEVLTAEKEQLQQQLRQPRPLSCTCCVL", "length": 405, "header": "tr|A0A287B2E0-1|A0A287B2E0_PIG Isoform 1 of Schlafen like 1 OS=Sus scrofa OX=9823 GN=SLFNL1 PE=4 SV=3 CANONICAL=A0A287B2E0-1" }, "isoforms": [ { "isoform_ac": "A0A287B2E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2E0/entry#A0A287B2E0-1", "sequence": { "sequence": "ETPRKTSLTQEQEPLMEPPGRQPLGELPAEASPPEDAGAEAAPSRRLLYVGHLNPQLPVPVLACLLRDALERLELPVAREHIEVVRRPREAFALVQVATHEDTLASLPWRLLAASGRHQIIQELVARGKELVLEEGWEPASRRAQENDGGPSPSPSPGPSPRSRFPPAWPPGTPPARAATPGQQSPPGCPRAAYSDSALVRQEILGQERLFQGALLGCETRNVEFKRGSGGYLSRAFKHHLRCYVCAFLNGEGGSLLVGVEDGGRVQGVRCSPRDEDRVRLLVDSVLQGFKPQVFPDAYRLEFIPVVGASATGAPLKVIRLSVQAPKAQAEPLLYETDKGEVFLRRDGSIQGPLSVHAIQEWCRQKWTAELRKLEERLEVLTAEKEQLQQQLRQPRPLSCTCCVL", "length": 405, "header": "tr|A0A287B2E0-1|A0A287B2E0_PIG Isoform 1 of Schlafen like 1 OS=Sus scrofa OX=9823 GN=SLFNL1 PE=4 SV=3 CANONICAL=A0A287B2E0-1" }, "locus": { "chromosome": "6", "start_pos": 170198626, "end_pos": 170194822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061035.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061035.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050322.3", "url": "https://www.ensembl.org/id/ENSSSCP00000050322.3" } ] } }, { "isoform_ac": "F1SF79-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2E0/entry#F1SF79-1", "sequence": { "sequence": "ETPRKTSLTQEQEPLMEPPGRQPLGELPAEASPPEDAGAEAAPSRRLLYVGHLNPQLPVPVLACLLRDALERLELPVAREHIEVVRRPREAFALVQVATHEDTLASLPWRLLAASGRHQIIQELVARGKELVLEEGWEPASRRAQENDGGPSPSPSPGPSPRSRFPPAWPPGTPPARAATPGQQSPPGCPRAAYSDSALVRQEILGQERLFQGALLGCETRNVEFKRGSGGYLSRAFKHHLRCYVCAFLNGEGGSLLVGVEDGGRVQGVRCSPRDEDRVRLLVDSVLQGFKPQVFPDAYRLEFIPVVGASATGAPLKKWTAELRKLEERLEVLTAEKEQLQQQLRQPRPLSCTCCVL", "length": 357, "header": "tr|F1SF79-1|A0A287B2E0_PIG Computationally mapped isoform of Schlafen like 1 OS=Sus scrofa OX=9823 GN=SLFNL1 PE=4 SV=5 CANONICAL=A0A287B2E0-1" }, "locus": { "chromosome": "6", "start_pos": 170198626, "end_pos": 170194822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004394.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004394.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004294.5", "url": "https://www.ensembl.org/id/ENSSSCP00000004294.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 180, "start_aa": "Thr", "end_pos": 180, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr180", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SF79", "url": "https://www.uniprot.org/uniprotkb/F1SF79" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287B2E0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 405, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287B2E0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287B2E0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287B2E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B2E0" }, { "id": "PF04326", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04326" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Schlafen AlbA-2", "eco_id": "ECO_0000259", "start_pos": 219, "end_pos": 350, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 180 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QS97-1", "uniprot_ac": "A0A5G2QS97", "uniprot_id": "A0A5G2QS97_PIG", "mass": { "chemical_mass": 116372.0, "monoisotopic_mass": 116372.0 }, "refseq": { "ac": "XP_020931132", "name": "leucine-rich repeat flightless-interacting protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931132" }, "gene_names": [ { "name": "LRRFIP1", "type": "recommended", "evidence": [ { "id": "A0A5G2QS97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97" } ] }, { "name": "LRRFIP1", "type": "synonym", "evidence": [ { "id": "XP_020931132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931132" } ] } ], "protein_names": [ { "name": "LRR binding FLII interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A5G2QS97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat flightless-interacting protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020931132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931132" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS97", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LRRFIP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97", "locus": {} } ], "crossref": [ { "id": "A0A5G2QS97", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QS97", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016330", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016330", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100517377", "url": "https://www.ncbi.nlm.nih.gov/gene/100517377", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZZI6", "url": "https://www.orthodb.org/?gene=A0A286ZZI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A287BIH9", "url": "https://www.orthodb.org/?gene=A0A287BIH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QS97", "url": "https://www.orthodb.org/?gene=A0A5G2QS97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19212", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19212", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19212:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19212:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09738", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09738", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020931132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931132", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZP61", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZP61-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZI6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIH9", "url": "https://www.uniprot.org/uniprotkb/A0A287BIH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BIH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS97", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS97-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW94-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2T8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJI2", "url": "https://www.uniprot.org/uniprotkb/F1SJI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJI2-1", "url": "https://www.uniprot.org/uniprotkb/F1SJI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJI5", "url": "https://www.uniprot.org/uniprotkb/F1SJI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJI5-1", "url": "https://www.uniprot.org/uniprotkb/F1SJI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LUF5", "url": "https://www.uniprot.org/uniprotkb/I3LUF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LUF5-1", "url": "https://www.uniprot.org/uniprotkb/I3LUF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDMGTQGSGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYYGLDSKWGDIEQWMEDSERYSRRSRRNTSASDEDERMSVGSRGSLRSQPDVEFGGPYAWTNGYDGELYGSQSLSRRSGRNSSYGGDGRFSTLSSAARDETLPFYLCSAARPAGSYRASVLGESSLAGARRGSACGSYAPSEHSGQLKSSSRASSRASSARASPVVEERSEKDFEKGSRSLPSLSAATLASLGGTSSRRGSGDTSISLDTEASIREIKELNELKDQIQDVEGRYMQGLKEMKDSLAEAEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDVLLELEEQLAESRRQLEEKSKEFEREKHAHSILQFQFAEVKEALKQREELLEEIRQLQQKQESYIREISDLQETIEWKDKKIGALERQKEFFDSIRSERDDLREEVVVLKEELKKHGIILNSETATNGETSDPLSRVEHPGSTKMTKEEVGAPQAPGDGTLGRASEVEVANEMVERVGKSEILPDSEQEQHKEEPVKDCADPEGLPPGETAEAPTTSADSGLSSGIFVNPTNEDQVQSPIPEHPPCLENTQQVQSREALHTAGDGPEASPGPSECSRQPDGEIPGPALEQDGGNAVESKPQRKESAEKQEGLQTTVEERSPEPPQESAPVQIADVEVERQSGADAGVQSQRPAEAVPEAELPGAGEQVGSGASSPPRCSDDPVSHQETGVADAPGGSDPGTGCDLEKEPAPHEVAEPAEGPVQSPEAGGGNSEEEGGGREFRGENPAGTEAPTVPCSPAAKHSPQEAVGPSTPDSESEPLDVKEPDEEKGACQGERPDASQKKTKNKKKKNKKKKSPAPVEAKDVQEELTLQSPDLSDGREDEQVKCADEKPGAEAQNGVPENPQQNEVAGSRADGRSPEDPHAEPERNPPCADADADTEAEEPGAAGDPGNREADAVPSSGTSARRKGSDQGVPEEAAAEQDAAAPGRLPGSEKDDVAGRAPLQDQSPSGDGKDASQMEDAEDSSPPVRGGSESLSLEGEGLAPAGELEGLDAECKDERRGGNGKGRSKDECALS", "length": 1082, "header": "tr|A0A5G2QS97-1|A0A5G2QS97_PIG Isoform 1 of LRR binding FLII interacting protein 1 OS=Sus scrofa OX=9823 GN=LRRFIP1 PE=1 SV=2 CANONICAL=A0A5G2QS97-1" }, "isoforms": [ { "isoform_ac": "A0A286ZP61-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97/entry#A0A286ZP61-1", "sequence": { "sequence": "MDMGTQGSGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKETNGYDGELYGSQSLSRRSGRNSSYGGDGRFSTLSSAARDETLASVLGESSLAGARRGSACGSYAPSEHSGQLKSSSRASSRASSARASPVVSGSRSLPSLSAATLASLGGTSSRRGSGDTSISLDTEASIREIKELNELKDQIQDVEGRYMQGLKEMKDSLAEAEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDVLLELEEQLAESRRQLEEKSKEFEREKHAHSILQFQFAEVKEALKQREELLEEIRQLQQKQESYIREISDLQETIEWKDKKIGALERQKEFFDSIRSERDDLREEVVVLKEELKKHGIILNSETATNGETSDPLSRVEHPGSTKMTKEEVGAPQAPGDGTLGRASEVEVANEMVERVGKSEILPDSEQEQHKEEPVKDCADPEGLPPGETAEAPTTSADSGLSSGIFVNPTNEDQVQSPIPEHPPCLENTQQVQSREALHTAGDGPEASPGPSECSRQPDGEIPGPALEQDGGNAVESKPQRKESAEKQEGLQTTVEERSPEPPQESAPVQIADVEVERQSGADAGVQSQRPAEAVPEAELPGAGEQVGSGASSPPRCSDDPVSHQETGVADAPGGSDPGTGCDLEKEPAPHEVAEPAEGPVQSPEAGGGNSEEEGGGREFRGENPAGTEAPTVPCSPAAKHSPQEAVGPSTPDSESEPLDVKEPDEEKGACQGERPDASQKKTKNKKKKNKKKKSPAPVEAKDVQEELTLQSPDLSDGREDEQVKCADEKPGAEAQNGVPENPQQNEVAGSRADGRSPEDPHAEPERNPPCADADADTEAEEPGAAGDPGNREADAVPSSGTSARRKGSDQGVPEEAAAEQDAAAPGRLPGSEKDDVAGRAPLQDQSPSGDGKDASQMEDAEDSSPPVRGGSESLSLEGEGLAPAGELEGLDAECKDERRGGNGKGRSKDECALS", "length": 991, "header": "tr|A0A286ZP61-1|A0A5G2QS97_PIG Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Sus scrofa OX=9823 GN=LRRFIP1 PE=1 SV=3 CANONICAL=A0A5G2QS97-1" }, "locus": { "chromosome": "15", "start_pos": 137426114, "end_pos": 137283350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040615.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040615.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033269.3", "url": "https://www.ensembl.org/id/ENSSSCP00000033269.3" } ] } }, { "isoform_ac": "A0A286ZZI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97/entry#A0A286ZZI6-1", "sequence": { "sequence": "MTNPAATQNKEIECLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERSEKDFEKGSRSLPSLSAATLASLGGTSSRRGSGDTSISLDTEASIREIKDSLAEAEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDVLLELEEQLAESRRQLEEKSKEFEREKHAHSILQFQFAEVKEALKQREELLEKHGIILNSETATNGETSDPLSRVEHPGSTKMTKEEVGAPQAPGDGTLGRASEVEVANEMVERVGKSEILPDSEQEQHKEEPVKDCADPEGLPPGETAEAPTTSADSGLSSGIFVNPTNEDQVQSPIPEHPPCLENTQQVQSREALHTAGDGPEASPGPSECSRQPDGEIPGPALEQDGGNAVESKPQRKESAEKQEGLQTTVEERSPEPPQESAPVQIADVEVERQSGADAGVQSQRPAEAVPEAELPGAGEQVGSGASSPPRCSDDPVSHQETGVADAPGGSDPGTGCDLEKEPAPHEVAEPAEGPVQSPEAGGGNSEEEGGGREFRGENPAGTEAPTVPCSPAAKHSPQEAVGPSTPDSESEPLDVKEPDEEKGACQGERPDASQKKTKNKKKKNKKKKSPAPVEAKDVQEELTLQSPDLSDGREDEQVKCADEKPGAEAQNGVPENPQQNEVAGSRADGRSPEDPHAEPERNPPCADADADTEAEEPGAAGDPGNREADAVPSSGTSARRKGSDQGVPEEAAAEQDAAAPGRLPGSEKDDVAGRAPLQDQSPSGDGKDASQMEDAEDSSPPVRGGSESLSLEGEGLAPAGELEGLDAECKDERRGGNGKGRSKDECALS", "length": 846, "header": "tr|A0A286ZZI6-1|A0A5G2QS97_PIG Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Sus scrofa OX=9823 GN=LRRFIP1 PE=1 SV=2 CANONICAL=A0A5G2QS97-1" }, "locus": { "chromosome": "15", "start_pos": 137426114, "end_pos": 137346026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047141.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047141.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037054.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037054.2" } ] } }, { "isoform_ac": "A0A287BIH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97/entry#A0A287BIH9-1", "sequence": { "sequence": "MTNPAATQNKEIECLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEASDEDERMSVGSRGSLRVEERSEKDFEKGSRSLPSLSAATLASLGGTSSRRGSGDTSISLDTEASIREIKDSLAEAEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDVLLELEEQLAESRRQLEEKSKEFEREKHAHSILQFQFAEVKEALKQREELLEKHGIILNSETATNGETSDPLSRVEHPGSTKMTKEEVGAPQAPGDGTLGRASEVEVANEMVERVGKSEILPDSEQEQHKEEPVKDCADPEGLPPGETAEAPTTSADSGLSSGIFVNPTNEDQVQSPIPEHPPCLENTQQVQSREALHTAGDGPEASPGPSECSRQPDGEIPGPALEQDGGNAVESKPQRKESAEKQEGLQTTVEERSPEPPQESAPVQIADVEVERQSGADAGVQSQRPAEAVPEAELPGAGEQVGSGASSPPRCSDDPVSHQETGVADAPGGSDPGTGCDLEKEPAPHEVAEPAEGPVQSPEAGGGNSEEEGGGREFRGENPAGTEAPTVPCSPAAKHSPQEAVGPSTPDSESEPLDVKEPDEEKGACQGERPDASQKKTKNKKKKNKKKKSPAPVEAKDVQEELTLQSPDLSDGREDEQVKCADEKPGAEAQNGVPENPQQNEVAGSRADGRSPEDPHAEPERNPPCADADADTEAEEPGAAGDPGNREADAVPSSGTSARRKGSDQGVPEEAAAEQDAAAPGRLPGSEKDDVAGRAPLQDQSPSGDGKDASQMEDAEDSSPPVRGGSESLSLEGEGLAPAGELEGLDAECKDERRGGNGKGRSKDECALS", "length": 831, "header": "tr|A0A287BIH9-1|A0A287BIH9_PIG Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Sus scrofa OX=9823 GN=LRRFIP1 PE=1 SV=3 CANONICAL=A0A5G2QS97-1" }, "locus": { "chromosome": "15", "start_pos": 137426114, "end_pos": 137346026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052224.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052224.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056340.3", "url": "https://www.ensembl.org/id/ENSSSCP00000056340.3" } ] } }, { "isoform_ac": "A0A5G2QS97-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97/entry#A0A5G2QS97-1", "sequence": { "sequence": "MDMGTQGSGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYYGLDSKWGDIEQWMEDSERYSRRSRRNTSASDEDERMSVGSRGSLRSQPDVEFGGPYAWTNGYDGELYGSQSLSRRSGRNSSYGGDGRFSTLSSAARDETLPFYLCSAARPAGSYRASVLGESSLAGARRGSACGSYAPSEHSGQLKSSSRASSRASSARASPVVEERSEKDFEKGSRSLPSLSAATLASLGGTSSRRGSGDTSISLDTEASIREIKELNELKDQIQDVEGRYMQGLKEMKDSLAEAEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDVLLELEEQLAESRRQLEEKSKEFEREKHAHSILQFQFAEVKEALKQREELLEEIRQLQQKQESYIREISDLQETIEWKDKKIGALERQKEFFDSIRSERDDLREEVVVLKEELKKHGIILNSETATNGETSDPLSRVEHPGSTKMTKEEVGAPQAPGDGTLGRASEVEVANEMVERVGKSEILPDSEQEQHKEEPVKDCADPEGLPPGETAEAPTTSADSGLSSGIFVNPTNEDQVQSPIPEHPPCLENTQQVQSREALHTAGDGPEASPGPSECSRQPDGEIPGPALEQDGGNAVESKPQRKESAEKQEGLQTTVEERSPEPPQESAPVQIADVEVERQSGADAGVQSQRPAEAVPEAELPGAGEQVGSGASSPPRCSDDPVSHQETGVADAPGGSDPGTGCDLEKEPAPHEVAEPAEGPVQSPEAGGGNSEEEGGGREFRGENPAGTEAPTVPCSPAAKHSPQEAVGPSTPDSESEPLDVKEPDEEKGACQGERPDASQKKTKNKKKKNKKKKSPAPVEAKDVQEELTLQSPDLSDGREDEQVKCADEKPGAEAQNGVPENPQQNEVAGSRADGRSPEDPHAEPERNPPCADADADTEAEEPGAAGDPGNREADAVPSSGTSARRKGSDQGVPEEAAAEQDAAAPGRLPGSEKDDVAGRAPLQDQSPSGDGKDASQMEDAEDSSPPVRGGSESLSLEGEGLAPAGELEGLDAECKDERRGGNGKGRSKDECALS", "length": 1082, "header": "tr|A0A5G2QS97-1|A0A5G2QS97_PIG Isoform 1 of LRR binding FLII interacting protein 1 OS=Sus scrofa OX=9823 GN=LRRFIP1 PE=1 SV=2 CANONICAL=A0A5G2QS97-1" }, "locus": { "chromosome": "15", "start_pos": 137426114, "end_pos": 137283350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086952.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086952.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061068.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061068.2" } ] } }, { "isoform_ac": "A0A5G2QW94-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97/entry#A0A5G2QW94-1", "sequence": { "sequence": "MDMGTQGSGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKEVTPGPSRSSSRGALLASADTRLLFRVQGSRSLPSLSAATLASLGGTSSRRGSGDTSISLDTEASIREIKDSLAEAEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDVLLELEEQLAESRRQLEEKSKEFEREKHAHSILQFQFAEVKEALKQREELLEKHGIILNSETATNGETSDPLSRVEHPGSTKMTKEEVGAPQAPGDGTLGRASEVEVANEMVERVGKSEILPDSEQEQHKEEPVKDCADPEGLPPGETAEAPTTSADSGLSSGIFVNPTNEDQVQSPIPEHPPCLENTQQVQSREALHTAGDGPEASPGPSECSRQPDGEIPGPALEQDGGNAVESKPQRKESAEKQEGLQTTVEERSPEPPQESAPVQIADVEVERQSGADAGVQSQRPAEAVPEAELPGAGEQVGSGASSPPRCSDDPVSHQETGVADAPGGSDPGTGCDLEKEPAPHEVAEPAEGPVQSPEAGGGNSEEEGGGREFRGENPAGTEAPTVPCSPAAKHSPQEAVGPSTPDSESEPLDVKEPDEEKGACQGERPDASQKKTKNKKKKNKKKKSPAPVEAKDVQEELTLQSPDLSDGREDEQVKCADEKPGAEAQNGVPENPQQNEVAGSRADGRSPEDPHAEPERNPPCADADADTEAEEPGAAGDPGNREADAVPSSGTSARRKGSDQGVPEEAAAEQDAAAPGRLPGSEKDDVAGRAPLQDQSPSGDGKDASQMEDAEDSSPPVRGGSESLSLEGEGLAPAGELEGLDAECKDERRGGNGKGRSKDECALS", "length": 840, "header": "tr|A0A5G2QW94-1|A0A5G2QW94_PIG Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Sus scrofa OX=9823 GN=LRRFIP1 PE=1 SV=2 CANONICAL=A0A5G2QS97-1" }, "locus": { "chromosome": "15", "start_pos": 137426114, "end_pos": 137283350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084072.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084072.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066208.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066208.2" } ] } }, { "isoform_ac": "A0A5G2R2T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97/entry#A0A5G2R2T8-1", "sequence": { "sequence": "MDMGTQGSGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYYGLDSKWGDIEQWMEDSERYSRRSRRNTSASDEDERMSVGSRGSLRSQPDVEFGGPYAWTNGYDGELYGSQSLSRRSGRNSSYGGDGRFSTLSSAARDETLASVLGESSLAGARRGSACGSYAPSEHSGQLKSSSRASSRASSARASPVVEERSEKDFEKGSRSLPSLSAATLASLGGTSSRRGSGDTSISLDTEASIREIKELNELKDQIQDVEGRYMQGLKEMKDSLAEAEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDVLLELEEQLAESRRQLEEKSKEFEREKHAHSILQFQFAEVKEALKQREELLEEIRQLQQKQESYIREISDLQETIEWKDKKIGALERQKEFFDSIRSERDDLREEVVVLKEELKKHGIILNSETATNGETSDPLSRVEHPGSTKMTKEEVGAPQAPGDGTLGRASEVEVANEMVERVGKSEILPDSEQEQHKEEPVKDCADPEGLPPGETAEAPTTSADSGLSSGIFVNPTNEDQVQSPIPEHPPCLENTQQVQSREALHTAGDGPEASPGPSECSRQPDGEIPGPALEQDGGNAVESKPQRKESAEKQEGLQTTVEERSPEPPQESAPVQIADVEVERQSGADAGVQSQRPAEAVPEAELPGAGEQVGSGASSPPRCSDDPVSHQETGVADAPGGSDPGTGCDLEKEPAPHEVAEPAEGPVQSPEAGGGNSEEEGGGREFRGENPAGTEAPTVPCSPAAKHSPQEAVGPSTPDSESEPLDVKEPDEEKGACQGERPDASQKKTKNKKKKNKKKKSPAPVEAKDVQEELTLQSPDLSDGREDEQVKCADEKPGAEAQNGVPENPQQNEVAGSRADGRSPEDPHAEPERNPPCADADADTEAEEPGAAGDPGNREADAVPSSGTSARRKGSDQGVPEEAAAEQDAAAPGRLPGSEKDDVAGRAPLQDQSPSGDGKDASQMEDAEDSSPPVRGGSESLSLEGEGLAPAGELEGLDAECKDERRGGNGKGRSKDECALS", "length": 1067, "header": "tr|A0A5G2R2T8-1|A0A5G2R2T8_PIG Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Sus scrofa OX=9823 GN=LRRFIP1 PE=1 SV=2 CANONICAL=A0A5G2QS97-1" }, "locus": { "chromosome": "15", "start_pos": 137426114, "end_pos": 137283350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072415.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072415.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071507.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071507.2" } ] } }, { "isoform_ac": "F1SJI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97/entry#F1SJI2-1", "sequence": { "sequence": "MDMGTQGSGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYYGLDSKWGDIEQWMEDSERYSRRSRRNTSASDEDERMSVGSRGSLRSQPDVEFGGPYAWTNGYDGELYGSQSLSRRSGRPFYLCSAARPAGSYRASVLGESSLAGARRGSACGSYAPSEHSGQLKSSSRASSRASSARASPVVEERSEKDFEKGSRSLPSLSAATLASLGGTSSRRGSGDTSISLDTEASIREIKELNELKDQIQDVEGRYMQGLKEMKDSLAEAEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDVLLELEEQLAESRRQLEEKSKEFEREKHAHSILQFQFAEVKEALKQREELLEEIRQLQQKQESYIREISDLQETIEWKDKKIGALERQKEFFDSIRSERDDLREEVVVLKEELKKHGIILNSETATNGETSDPLSRVEHPGSTKMTKEEVGAPQAPGDGTLDIRLKKLVDEREGLLEQIKKLRGQLEERQKNVRLDSLRPEDGVLENGTDVHVMDLHRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKLAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSVHLSQQ", "length": 639, "header": "tr|F1SJI2-1|F1SJI2_PIG Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Sus scrofa OX=9823 GN=LRRFIP1 PE=1 SV=4 CANONICAL=A0A5G2QS97-1" }, "locus": { "chromosome": "15", "start_pos": 137438653, "end_pos": 137283350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017786.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017786.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017305.4", "url": "https://www.ensembl.org/id/ENSSSCP00000017305.4" } ] } }, { "isoform_ac": "F1SJI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97/entry#F1SJI5-1", "sequence": { "sequence": "MTNPAATQNKEIECLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYYGLDSKWGDIEQWMEDSERYSRRSRRNTSASDEDERMSVGSRGSLRSQPDVEFGGPYAWTNGYDGELYGSQSLSRRSGRNSSYGGDGRFSTLSSAARDETLPFYLCSAARPAGSYRASVLGESSLAGARRGSACGSYAPSEHSGQLKSSSRASSRASSARASPVVEERSEKDFEKGSRSLPSLSAATLASLGGTSSRRGSGDTSISLDTEASIREIKELNELKDQIQDVEGRYMQGLKEMKDSLAEAEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDVLLELEEQLAESRRQLEEKSKEFEREKHAHSILQFQFAEVKEALKQREELLEEIRQLQQKQESYIREISDLQETIEWKDKKIGALERQKEFFDSIRSERDDLREEVVVLKEELKKHGIILNSETATNGETSDPLSRVEHPGSTKMTKEEVGAPQAPGDGTLDIRLKKLVDEREGLLEQIKKLRGQLEERQKNVRLDSLRPEDGVLENGTDVHVMDLHRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKLAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSVHLSQQ", "length": 651, "header": "tr|F1SJI5-1|F1SJI5_PIG Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Sus scrofa OX=9823 GN=LRRFIP1 PE=1 SV=4 CANONICAL=A0A5G2QS97-1" }, "locus": { "chromosome": "15", "start_pos": 137438653, "end_pos": 137346026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017783.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017783.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017302.4", "url": "https://www.ensembl.org/id/ENSSSCP00000017302.4" } ] } }, { "isoform_ac": "I3LUF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97/entry#I3LUF5-1", "sequence": { "sequence": "MDMGTQGSGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKEKYYGLDSKWGDIEQWMEDSERYSRRSRRNTSASDEDERMSVGSRGSLRSQPDVEFGGPYAWTNGYDGELYGSQSLSRRSGRNSSYGGDGRFSTLSSAARDETLASVLGESSLAGARRGSACGSYAPSEHSGQLKSSSRASSRASSARASPVVEERSEKDFEKGSRSLPSLSAATLASLGGTSSRRGSGDTSISLDTEASIREIKELNELKDQIQDVEGRYMQGLKEMKDSLAEAEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDVLLELEEQLAESRRQLEEKSKEFEREKHAHSILQFQFAEVKEALKQREELLEEIRQLQQKQESYIREISDLQETIEWKDKKIGALERQKEFFDSIRSERDDLREEVVVLKEELKKHGIILNSETATNGETSDPLSRVEHPGSTKMTKEEVGAPQAPGDGTLDIRLKKLVDEREGLLEQIKKLRGQLEERQKNVRLDSLRPEDGVLENGTDVHVMDLHRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKLAAENAEKIEDELKAEKRKLQRELRSALDKTEELEVSNGHLVKRLEKMKANRSVHLSQQ", "length": 640, "header": "tr|I3LUF5-1|A0A5G2QS97_PIG Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Sus scrofa OX=9823 GN=LRRFIP1 PE=1 SV=2 CANONICAL=A0A5G2QS97-1" }, "locus": { "chromosome": "15", "start_pos": 137438653, "end_pos": 137283350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030900.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030900.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027755.2", "url": "https://www.ensembl.org/id/ENSSSCP00000027755.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP61", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP61" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS97", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS97", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS97", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS97", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QS97-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1082, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QS97-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QS97" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRV7-1", "uniprot_ac": "A0A5G2QRV7", "uniprot_id": "A0A5G2QRV7_PIG", "mass": { "chemical_mass": 196061.0, "monoisotopic_mass": 196061.0 }, "refseq": { "ac": "XP_020927871", "name": "probable ATP-dependent RNA helicase DDX60 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020927871" }, "gene_names": [ { "name": "DDX60", "type": "recommended", "evidence": [ { "id": "A0A5G2QRV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ] }, { "name": "DDX60", "type": "synonym", "evidence": [ { "id": "XP_020927871", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020927871" } ] } ], "protein_names": [ { "name": "DExD/H-box helicase 60", "type": "synonym", "evidence": [ { "id": "A0A5G2QRV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7/entry#names_and_taxonomy" } ] }, { "name": "probable ATP-dependent RNA helicase DDX60 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020927871", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020927871" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DDX60", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7", "locus": { "chromosome": "14", "start_pos": 21163561, "end_pos": 21083350, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009720", "url": "https://www.ensembl.org/id/ENSSSCG00000009720" } ] } } ], "crossref": [ { "id": "ENSSSCG00000009720", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009720", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18025", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18025", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18795", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18795", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100158037", "url": "https://www.ncbi.nlm.nih.gov/gene/100158037", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100158037", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158037", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDNRINE", "url": "https://omabrowser.org/oma/group/QDNRINE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QRV7", "url": "https://www.orthodb.org/?gene=A0A5G2QRV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44533", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44533", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44533:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44533:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26167", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26167", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020927871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020927871", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZWX9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZWX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ABK4", "url": "https://www.uniprot.org/uniprotkb/A0A287ABK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ABK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AD25", "url": "https://www.uniprot.org/uniprotkb/A0A287AD25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AD25-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AD25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A287AEZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AEZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AEZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BEN8", "url": "https://www.uniprot.org/uniprotkb/A0A287BEN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BEN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BEN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BFN9", "url": "https://www.uniprot.org/uniprotkb/A0A287BFN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BFN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BFN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QGU8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QGU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6W4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6W4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLEKYMMFLEDMSQLILNEVPKADYDSLFNDFVESEFFLLDGDSLLIMCVCEKSLKQGQDLHFFYLVERYLVDLITKGGQFAVVFFKDAENTYFNLPELLPLRTALILHLQHNTNIDVRTDFSGCLSQEWEAFLEESYPYFLIVADEGLNNLQTHLFNFLIIQSWALKINAVLFAGQVADVLRLYAYFMPSRHKNQMFFQKNRRTIENAYRSLIKQLEKCRALAFAPLFGNLKWENMMEEAHETISLLKQLWPEGSDIRRVLCVTSCSLSLRFYHQLLESRSETTAAHQQVEGKPLALQEVEDLCKLHCLSVAFLLCLPLSQRACTRFVTSHWIEDIQTFLKMKKCCDYFILSDVNISESWNLDLTHLSDLSDELLLKNIAFYYENENAQGLHLGNVITKDYEHLWDTVSKLVRPFDVGKPFPLRTTKRPFLKKNPSPIKDTSMEKMPSLGFIPMSCQVVDNFVGDILKDLPFLTSDDPVVTSLVKQKEFDELVHWHSHKPLSDDYDRTKCQFNEKSRDPYYLRSVQKYHVFQRFYGNSLESVSSKFVVTQGIKPRKFYGPTSKKTQETKAEIITRENKKRLLAKEEEKEEKKWSVLSFSIEEEMKEDLNSGIKNLEDFLKSCKSSSVKFRVEMVGLTACLKAWKEYCQSEGETTKDLSIAVQMMKRIYSVVEKYPELLQEADRQVIAKCLRYLGFEELASSLHLTQVAGNVTKEKRKNKYSVGIGPARFQLQYMGPYLLRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMERVLREGDDGVVVYVAPTKALVNQVAATVQNRFRKNLPDGEALCGVFTRDYRHDALNSQILITVPACFEILLLAPHRQAWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKQADERMGQNIASRSVGCRPGSRKDCLLAKQSYRVRLVLYGERYNDLEKHICSVNNGVISFNHFHPCAALTTDHIEKYGFPSDLTLSPREMVQLYDTMFHFWAGWPRAQELCPEEFIHFKNKIVIKKSDTRKYEESLKAELTDWVKSGCVKQARMVLKHLRPGSVISSENMADMFPLLVEKLKQMEKLPALFFLFKLGAVEERARSVKTFLEKKQQRKRPPKADKEAHDMENKLRKVRKSIEKQKTIDEKSLKKPRNMDQSLIHEAEHDNLLKVLEKNLEIPQDCTYADQKALDAQTLQTVFDRVKLTRKGAELKALAARGVGYHHSSLNFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSIYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIEKLIKSNVPQLRGQFPLSISLVLRLMLLASKGDDPGDAQAKVLSVLKHSLLSFKQPRTLEMLKLYFLFALQFLVKEGYLDREGNPVGFAGLVSHLHYHEPSNLVFVSFLVRGLFHNLCQPTRKGSKLFSQDVMEKLVLVLANLFGRTYFPAKFHESPPKFYQSKVFLEDLPKDFKDALDQYNKNVTEDFASFLMIVSRLADMKQEYQLPLSHTDFSGEECEDSQLASYLMSCKEGRVAISPFVCLSGNSDGDLLCPGTLDHVTLRTIGISSSQAPVLCPQRFDNQGRKMPLNAYALDFYKHGSLTGLVQDNRMNEGLAYQLLKDFALTIQSISVSLRELCVNEEDNVVLAFEQLSKSFLEKFNKI", "length": 1704, "header": "tr|A0A5G2QRV7-1|A0A5G2QRV7_PIG Isoform 1 of DExD/H-box helicase 60 OS=Sus scrofa OX=9823 GN=DDX60 PE=1 SV=1 CANONICAL=A0A5G2QRV7-1" }, "isoforms": [ { "isoform_ac": "A0A286ZWX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7/entry#A0A286ZWX9-1", "sequence": { "sequence": "MDLEKYMMFLEDMSQLILNEVPKADYDSLFNDFVESEFFLLDGDSLLIMCVCEKSLKQGQDLHFFYLVERYLVDLITKGGQFAVVFFKDAENTYFNLPELLPLRTALILHLQHNTNIDVRTDFSGCLSQEWEAFLEESYPYFLIVADEGLNNLQTHLFNFLIIQSWALKINAVLFAGQVADVLRLYAYFMPSRHKNQMFFQKNRRTIENAYRSLIKQLEKCRALAFAPLFGNLKWENMMEEAHETISLLKQLWPEGSDIRRVLCVTSCSLSLRFYHQLLESRSETTAAHQQVEGKPLALQEVEDLCKLHCLSVAFLLCLPLSQRACTRFVTSHWIEDIQTFLKMKKCCDYFILSDVNISESWNLDLTHLSDLSDELLLKNIAFYYENENAQGLHLGNVITKDYEHLWDTVSKLVRPFDVGKPFPLRTTKRPFLKKNPSPIKDTSMEKMPSLGFIPMSCQVVDNFVGDILKDLPFLTSDDPVVTSLVKQKEFDELVHWHSHKPLSDDYDRTKCQFNEKSRDPYYLRSVQKYHVFQRFYGNSLESVSSKFVVTQGIKPRKFYGPTSKKTQETKAEIITRENKKRLLAKEEEKEEKKWSVLSFSIEEEMKEDLNSGIKNLEDFLKSCKSSSVKFRVEMVGLTACLKAWKEYCQSEGETTKDLSIAVQMMKRIYSVVEKYPELLQEADRQVIAKCLRYLGFEELASSLHLTQVAGNVTKEKRKNKYSVGIGPARFQLQYMGPYLLRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMERVLREGDDGVVVYVAPTKALVNQVAATVQNRFRKNLPDGEALCGVFTRDYRHDALNSQILITVPACFEILLLAPHRQAWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKQADERMGQNIASRSVGCRPGSRKDCLLAKQSYRVRLVLYGERYNDLEKHICSVNNGVISFNHFHPCAALTTDHIEKYGFPSDLTLSPREMVQLYDTMFHFWAGWPRAQELCPEEFIHFKNKIVIKKSDTRKYEESLKAELTDWVKSGCVKQARMVLKHLRPGSVISSENMADMFPLLVEKLKQMEKLPALFFLFKLGAVEERARSVKTFLEKKQQRKRPPKADKEAHDMENKLRKVRKSIEKQKTIDEKSLKKPRNMDQSLIHEAEHDNLLKVLEKNLEIPQDCTYADQKALDAQVVTATGTLALGINMPCKSVVFAQNSIYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIEKLIKSNVPQLRGQFPLSISLVLRLMLLASKGDDPGDAQAKVLSVLKHSLLSFKQPRTLEMLKLYFLFALQFLVKEGYLDREGNPVGFAGLVSHLHYHEPSNLVFVSFLVRGLFHNLCQPTRKGSKLFSQDVMEKLVLVLANLFGRTYFPAKFHESPPKFYQSKVFLEDLPKDFKDALDQYNKNVTEDFASFLMIVSRLADMKQEYQLPLSHTDFSGEECEDSQLASYLMSCKEGRVAISPFVCLSGNSDGDLLCPGTLDHVTLRTIGISSSQAPVLCPQRFDNQGRKMPLNAYALDFYKHGSLTGLVQDNRMNEGLAYQLLKDFALTIQSISVSLRELCVNEEDNVVLAFEQLSKSFLEKFNKI", "length": 1653, "header": "tr|A0A286ZWX9-1|A0A5G2QRV7_PIG Computationally mapped isoform of DExD/H-box helicase 60 OS=Sus scrofa OX=9823 GN=DDX60 PE=1 SV=1 CANONICAL=A0A5G2QRV7-1" }, "locus": { "chromosome": "14", "start_pos": 21162923, "end_pos": 21089421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049404.1", "url": "https://www.ensembl.org/id/ENSSSCT00000049404.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036145.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036145.1" } ] } }, { "isoform_ac": "A0A287ABK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7/entry#A0A287ABK4-1", "sequence": { "sequence": "MDLEKYMMFLEDMSQLILNEVPKADYDSLFNDFVESEFFLLDGDSLLIMCVCEKSLKQGQDLHFFYLVERYLVDLITKGGQFAVVFFKDAENTYFNLPELLPLRTALILHLQHNTNIDVRTDFSGCLSQEWEAFLEESYPYFLIVADEGLNNLQTHLFNFLIIQSWALKINAVLFAGQVADVLRLYAYFMPSRHKNQMFFQKNRRTIENAYRSLIKQLEKCRALAFAPLFGNLKWENMMEEAHETISLLKQLWPEGSDIRRVLCVTSCSLSLRFYHQLLESRSETTAAHQQVEGKPLALQEVEDLCKLHCLSVAFLLCLPLSQRACTRFVTSHWIEDIQTFLKMKKCCDYFILSDVNISESWNLDLTHLSDLSDELLLKNIAFYYENENAQGLHLGNVITKDYEHLWDTVSKLVRPFDVGKPFPLRTTKRPFLKKNPSPIKDTSMEKMPSLGFIPMSCQVVDNFVGDILKDLPFLTSDDPVVTSLVKQKEFDELVHWHSHKPLSDDYDRTKCQFNEKSRDPYYLRSVQKYHVFQRFYGNSLESVSSKFVVTQGIKPRKFYGPTSKKTQETKAEIITRENKKRLLAKEEEKEEKKWSVLSFSIEEEMKEDLNSGIKNLEDFLKSCKSSSVKFRVEMVGLTACLKAWKEYCQSEGETTKDLSIAVQMMKRIYSVVEKYPELLQEADRQVIAKCLRYLGFEELASSLHLTQVAGNVTKEKRKNKYSVGIGPARFQLQYMGPYLLRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMERVLREGDDGVVVYVAPTKALVNQVAATVQNRFRKNLPDGEALCGVFTRDYRHDALNSQILITVPACFEILLLAPHRQAWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKQADERMGQNIASRSVGCRPGSRKDCLLAKQSYRVRLVLYGERYNDLEKHICSVNNGVISFNHFHPCAALTTDHIEKYGFPSDLTLSPREMVQLYDTMFHFWAGWPRAQELCPEEFIHFKNKIVIKKSDTRKYEESLKAELTDWVKSGCVKQARMVLKHLRPGSVISSENMADMFPLLVEKLKQMEKLPALFFLFKLGAVEERARSVKTFLEKKQQRKRPPKADKEAHDMENKLRKVRKSIEKQKTIDEKSLKKPRNMDQSLIHEAEHDNLLKVLEKNLEIPQDCTYADQKALDAQTLQTVFDRVKLTRKGAELKALAARGVGYHHSSLNFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSIYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIEKLIKSNVPQLRGQFPLSISLVLRLMLLASKGDDPGDAQAKVLSVLKHSLLSFKQPRTLEMLKLYFLFALQFLVKEGYLDREGNPVGFAGLVSHLHYHEPSNLVFVSFLVRGLFHNLCQPTRKGSKLFSQDVMEKLVLVLANLFGRTYFPAKFHESPPKFYQSKVFLEDLPKDFKDALDQYNKNVTEDFASFLMIVSRLADMKQEYQLPLSHTDFSGEECEDSQLASYLMSCKEGRVAISPFVCLSGNSDGDLLCPGTLDHKLGSPRSRYWLIQFLARLLPGLSVVTLL", "length": 1628, "header": "tr|A0A287ABK4-1|A0A5G2QRV7_PIG Computationally mapped isoform of DExD/H-box helicase 60 OS=Sus scrofa OX=9823 GN=DDX60 PE=1 SV=3 CANONICAL=A0A5G2QRV7-1" }, "locus": { "chromosome": "14", "start_pos": 21156022, "end_pos": 21089421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047342.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047342.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041274.3", "url": "https://www.ensembl.org/id/ENSSSCP00000041274.3" } ] } }, { "isoform_ac": "A0A287AD25-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7/entry#A0A287AD25-1", "sequence": { "sequence": "MDLEKYMMFLEDMSQLILNEVPKADYDSLFNDFVESEFFLLDGDSLLIMCVCEKSLKQGQDLHFFYLVERYLVDLITKGGQFAVVFFKDAENTYFNLPELLPLRTALILHLQHNTNIDVRTDFSGCLSQEWEAFLEESYPYFLIVADEGLNNLQTHLFNFLIIQSWALKINAVLFAGQVADVLRLYAYFMPSRHKNQMFFQKNRRTIENAYRSLIKQLEKCRALAFAPLFGNLKWENMMEEAHETISLLKQLWPEGSDIRRVLCVTSCSLSLRFYHQLLESRSETTAAHQQVEGKPLALQEVEDLCKLHCLSVAFLLCLPLSQRACTRFVTSHWIEDIQTFLKMKKCCDYFILSDVNISESWNLDLTHLSDLSDELLLKNIAFYYENENAQGLHLGNVITKDYEHLWDTVSKLVRPFDVGKPFPLRTTKRPFLKKNPSPIKDTSMEKMPSLGFIPMSCQVVDNFVGDILKDLPFLTSDDPVVTSLVKQKEFDELVHWHSHKPLSDDYDRTKCQFNEKSRDPYYLRSVQKYHVFQRFYGNSLESVSSKFVVTQGIKPRKFYGPTSKKTQETKAEIITRENKKRLLAKEEEKEEKKWSVLSFSIEEEMKEDLNSGIKNLEDFLKSCKSSSVKFRVEMVGLTACLKAWKEYCQSEGETTKDLSIAVQMMKRIYSVVEKYPELLQEADRQVIAKCLRYLGFEELASSLHLTQVAGNVTKEKRKNKYSVGIGPARFQLQYMGPYLLRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMERVLREGDDGVVVYVAPTKALVNQVAATVQNRFRKNLPDGEALCGVFTRDYRHDALNSQILITVPACFEILLLAPHRQAWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKQADERMGQNIASRSVGCRPGSRKDCLLAKQSYRVRLVLYGERYNDLEKHICSVNNGVISFNHFHPCAALTTDHIEKYGFPSDLTLSPREMVQLYDTMFHFWAGWPRAQELCPEEFIHFKNKIVIKKSDTRKYEESLKAELTDWVKSGCVKQARMVLKHLRPGSVISSENMADMFPLLVEKLKQMEKLPALFFLFKLGAVEERARSVKTFLEKKQQRKRPPKADKEAHDMENKLRKVRKSIEKQKTIDEKSLKKPRNMDQSLIHEAEHDNLLKVLEKNLEIPQDCTYADQKALDAQTLQTVFDRVKLTRKGAELKALAARGVGYHHSSLNFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSIYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIEKLIKSNVPQLRGQFPLSISLVLRLMLLASKGDDPGDALEMLKLYFLFALQFLVKEGYLDREGNPVGFAGLVSHLHYHEPSNLVFVSFLVRGLFHNLCQPTRKGSKLFSQDVMEKLVLVLANLFGRTYFPAKFHESPPKFYQSKVFLEDLPKDFKDALDQYNKNVTEDFASFLMIVSRLADMKQEYQLPLSHTDFSGEECEDSQLASYLMSCKEGRVAISPFVCLSGNSDGDLLCPGTLDHVTLRTIGISSSQAPVLCPQRFDNQGRKMPLNAYALDFYKHGSLTGLVQDNRMNEGLAYQLLKDFALTIQSISVSLRELCVNEEDNVVLAFEQLSKSFLEKFNKI", "length": 1684, "header": "tr|A0A287AD25-1|A0A5G2QRV7_PIG Computationally mapped isoform of DExD/H-box helicase 60 OS=Sus scrofa OX=9823 GN=DDX60 PE=1 SV=3 CANONICAL=A0A5G2QRV7-1" }, "locus": { "chromosome": "14", "start_pos": 21162923, "end_pos": 21089421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065233.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065233.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041909.3", "url": "https://www.ensembl.org/id/ENSSSCP00000041909.3" } ] } }, { "isoform_ac": "A0A287AEZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7/entry#A0A287AEZ8-1", "sequence": { "sequence": "MDLEKYMMFLEDMSQLILNEVPKADYDSLFNDFVESEFFLLDGDSLLIMCVCEKSLKQGQDLHFFYLVERYLVDLITKGGQFAVVFFKDAENTYFNLPELLPLRTALILHLQHNTNIDVRTDFSGCLSQEWEAFLEESYPYFLIVADEGLNNLQTHLFNFLIIQSWALKINAVLFAGQVADVLRLYAYFMPSRHKNQMFFQKAHETISLLKQLWPEGSDIRRVLCVTSCSLSLRFYHQLLESRSETTAAHQQVEGKPLALQEVEDLCKLHCLSVAFLLCLPLSQRACTRFVTSHWIEDIQTFLKMKKCCDYFILSDVNISESWNLDLTHLSDLSDELLLKNIAFYYENENAQGLHLGNVITKDYEHLWDTVSKLVRPFDVGKPFPLRTTKRPFLKKNPSPIKDTSMEKMPSLGFIPMSCQVVDNFVGDILKDLPFLTSDDPVVTSLVKQKEFDELVHWHSHKPLSDDYDRTKCQFNEKSRDPYYLRSVQKYHVFQRFYGNSLESVSSKFVVTQGIKPRKFYGPTSKKTQETKAEIITRENKKRLLAKEEEKEEKKWSVLSFSIEEEMKEDLNSGIKNLEDFLKSCKSSSVKFRVEMVGLTACLKAWKEYCQSEGETTKDLSIAVQMMKRIYSVVEKYPELLQEADRQVIAKCLRYLGFEELASSLHLTQVAGNVTKEKRKNKYSVGIGPARFQLQYMGPYLLRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMERVLREGDDGVVVYVAPTKALVNQVAATVQNRFRKNLPDGEALCGVFTRDYRHDALNSQILITVPACFEILLLAPHRQAWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKQADERMGQNIASRSVGCRPGSRKDCLLAKQSYRVRLVLYGERYNDLEKHICSVNNGVISFNHFHPCAALTTDHIEKYGFPSDLTLSPREMVQLYDTMFHFWAGWPRAQELCPEEFIHFKNKIVIKKSDTRKYEESLKAELTDWVKSGCVKQARMVLKHLRPGSVISSENMADMFPLLVEKLKQMEKLPALFFLFKLGAVEERARSVKTFLEKKQQRKRPPKADKEAHDMENKLRKVRKSIEKQKTIDEKSLKKPRNMDQSLIHEAEHDNLLKVLEKNLEIPQDCTYADQKALDAQTLQTVFDRVKLTRKGAELKALAARGVGYHHSSLNFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSIYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIEKLIKSNVPQLRGQFPLSISLVLRLMLLASKGDDPGDAQAKVLSVLKHSLLSFKQPRTLEMLKLYFLFALQFLVKEGYLDREGNPVGFAGLVSHLHYHEPSNLVFVSFLVRGLFHNLCQPTRKGSKLFSQDVMEKLVLVLANLFGRTYFPAKFHESPPKFYQSKVFLEDLPKDFKDALDQYNKNVTEDFASFLMIVSRLADMKQEYQLPLSHTDFSGEECEDSQLASYLMSCKEGRVAISPFVCLSGNSDGDLLCPGTLDHVTLRTIGISSSQAPVLCPQRFDNQGRKMPLNAYALDFYKHGSLTGLVQDNRMNEGLAYQLLKDFALTIQSISVSLRELCVNEEDNVVLAFEQLSKSFLEKFNKI", "length": 1665, "header": "tr|A0A287AEZ8-1|A0A5G2QRV7_PIG Computationally mapped isoform of DExD/H-box helicase 60 OS=Sus scrofa OX=9823 GN=DDX60 PE=1 SV=1 CANONICAL=A0A5G2QRV7-1" }, "locus": { "chromosome": "14", "start_pos": 21162923, "end_pos": 21089421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039842.1", "url": "https://www.ensembl.org/id/ENSSSCT00000039842.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042601.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042601.1" } ] } }, { "isoform_ac": "A0A287BEN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7/entry#A0A287BEN8-1", "sequence": { "sequence": "MDLEKYMMFLEDMSQLILNEVPKADYDSLFNDFVESEFFLLDGDSLLIMCVCEKSLKQGQDLHFFYLVERYLVDLITKGGQFAVVFFKDAENTYFNLPELLPLRTALILHLQHNTNIDVRTDFSGCLSQEWEAFLEESYPYFLIVADEGLNNLQTHLFNFLIIQSWALKINAVLFAGQVADVLRLYAYFMPSRHKNQMFFQKNRRTIENAYRSLIKQLEKCRALAFAPLFGNLKWENMMEEAHETISLLKQLWPEGSDIRRVLCVTSCSLSLRFYHQLLESRSETTAAHQQVEGKPLALQEVEDLCKLHCLSVAFLLCLPLSQRACTRFVTSHWIEDIQTFLKMKKCCDYFILSDVNISESWNLDLTHLSDLSDELLLKNIAFYYENENAQGLHLGNVITKDYEHLWDTVSKLVRPFDVGKPFPLRTTKRPFLKKNPSPIKDTSMEKMPSLGFIPMSCQVVDNFVGDILKDLPFLTSDDPVVTSLVKQKEFDELVHWHSHKPLSDDYDRTKCQFNEKSRDPYYLRSVQKYHVFQRFYGNSLESVSSKFVVTQGIKPRKFYGPTSKKTQETKAEIITRENKKRLLAKEEEKEEKKWSVLSFSIEEEMKEDLNSGIKNLEDFLKSCKSSSVKFRVEMVGLTACLKAWKEYCQSEGETTKDLSIAVQMMKRIYSVVEKYPELLQEADRQVIAKCLRYLGFEELASSLHLTQVAGNVTKEKRKNKYSVGIGPARFQLQYMGPYLLRDERKDPDPRVQDFIPDTWQALVNQVAATVQNRFRKNLPDGEALCGVFTRDYRHDALNSQILITVPACFEILLLAPHRQAWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKQADERMGQNIASRSVGCRPGSRKDCLLAKQSYRVRLVLYGERYNDLEKHICSVNNGVISFNHFHPCAALTTDHIEKYGFPSDLTLSPREMVQLYDTMFHFWAGWPRAQELCPEEFIHFKNKIVIKKSDTRKYEESLKAELTDWVKSGCVKQARMVLKHLRPGSVISSENMADMFPLLVEKLKQMEKLPALFFLFKLGAVEERARSVKTFLEKKQQRKRPPKADKEAHDMENKLRKVRKSIEKQKTIDEKSLKKPRNMDQSLIHEAEHDNLLKVLEKNLEIPQDCTYADQKALDAQTLQTVFDRVKLTRKGAELKALAARGVGYHHSSLNFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSIYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIEKLIKSNVPQLRGQFPLSISLVLRLMLLASKGDDPGDAQAKVLSVLKHSLLSFKQPRTLEMLKLYFLFALQFLVKEGYLDREGNPVGFAGLVSHLHYHEPSNLVFVSFLVRGLFHNLCQPTRKGSKLFSQDVMEKLVLVLANLFGRTYFPAKFHESPPKFYQSKVFLEDLPKDFKDALDQYNKNVTEDFASFLMIVSRLADMKQEYQLPLSHTDFSGEECEDSQLASYLMSCKEGRVAISPFVCLSGNSDGDLLCPGTLDHVTLRTIGISSSQAPVLCPQRFDNQGRKMPLNAYALDFYKHGSLTGLVQDNRMNEGLAYQLLKDFALTIQSISVSLRELCVNEEDNVVLAFEQLSKSFLEKFNKI", "length": 1654, "header": "tr|A0A287BEN8-1|A0A287BEN8_PIG Computationally mapped isoform of DExD/H-box helicase 60 OS=Sus scrofa OX=9823 GN=DDX60 PE=1 SV=1 CANONICAL=A0A5G2QRV7-1" }, "locus": { "chromosome": "14", "start_pos": 21162923, "end_pos": 21089421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061116.1", "url": "https://www.ensembl.org/id/ENSSSCT00000061116.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054579.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054579.1" } ] } }, { "isoform_ac": "A0A287BFN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7/entry#A0A287BFN9-1", "sequence": { "sequence": "MDLEKYMMFLEDMSQLILNEVPKADYDSLFNDFVESEFFLLDGDSLLIMCVCEKSLKQGQDLHFFYLVERYLVDLITKGGQFAVVFFKDAENTYFNLPELLPLRTALILHLQHNTNIDVRTDFSGCLSQEWEAFLEESYPYFLIVADEGLNNLQTHLFNFLIIQSWALKINAVLFAGQVADVLRLYAYFMPSRHKNQMFFQKNRRTIENAYRSLIKQLEKCRALAFAPLFGNLKWENMMEEAHETISLLKQLWPEGSDIRRVLCVTSCSLSLRFYHQLLESRSETTAAHQQVEGKPLALQEVEDLCKLHCLSVAFLLCLPLSQRACTRFVTSHWIEDIQTFLKMKKCCDYFILSDVNISESWNLDLTHLSDLSDELLLKNIAFYYENENAQGLHLGNVITKDYEHLWDTVSKLVRPFDVGKPFPLRTTKRPFLKKNPSPIKDTSMEKMPSLGFIPMSCQVVDNFVGDILKDLPFLTSDDPVVTSLVKQKEFDELVHWHSHKPLSDDYDRTKCQFNEKSRDPYYLRSVQKYHVFQRFYGNSLESVSSKFVVTQGIKPRKFYGPTSKKTQETKAEIITRENKKRLLAKEEEKEEKKWSVLSFSIEEEMKEDLNSGIKNLEDFLKSCKSSSVKFRVEMVGLTACLKAWKEYCQSEGETTKDLSIAVQMMKRIYSVVEKYPELLQEADRQVIAKCLRYLGFEELASSLHLTQVAGNVTKEKRKNKYSVGIGPARFQLQYMGPYLLRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMERVLREGDDGVVVYVAPTKILITVPACFEILLLAPHRQAWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKQADERMGQNIASRSVGCRPGSRKDCLLAKQSYRVRLVLYGERYNDLEKHICSVNNGVISFNHFHPCAALTTDHIEKYGFPSDLTLSPREMVQLYDTMFHFWAGWPRAQELCPEEFIHFKNKIVIKKSDTRKYEESLKAELTDWVKSGCVKQARMVLKHLRPGSVISSENMADMFPLLVEKLKQMEKLPALFFLFKLGAVEERARSVKTFLEKKQQRKRPPKADKEAHDMENKLRKVRKSIEKQKTIDEKSLKKPRNMDQSLIHEAEHDNLLKVLEKNLEIPQDCTYADQKALDAQTLQTVFDRVKLTRKGAELKALAARGVGYHHSSLNFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSIYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIEKLIKSNVPQLRGQFPLSISLVLRLMLLASKGDDPGDAQAKVLSVLKHSLLSFKQPRTLEMLKLYFLFALQFLVKEGYLDREGNPVGFAGLVSHLHYHEPSNLVFVSFLVRGLFHNLCQPTRKGSKLFSQDVMEKLVLVLANLFGRTYFPAKFHESPPKFYQSKVFLEDLPKDFKDALDQYNKNVTEDFASFLMIVSRLADMKQEYQLPLSHTDFSGEECEDSQLASYLMSCKEGRVAISPFVCLSGNSDGDLLCPGTLDHVTLRTIGISSSQAPVLCPQRFDNQGRKMPLNAYALDFYKHGSLTGLVQDNRMNEGLAYQLLKDFALTIQSISVSLRELCVNEEDNVVLAFEQLSKSFLEKFNKI", "length": 1664, "header": "tr|A0A287BFN9-1|A0A287BFN9_PIG Computationally mapped isoform of DExD/H-box helicase 60 OS=Sus scrofa OX=9823 GN=DDX60 PE=1 SV=1 CANONICAL=A0A5G2QRV7-1" }, "locus": { "chromosome": "14", "start_pos": 21162923, "end_pos": 21089421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041121.2", "url": "https://www.ensembl.org/id/ENSSSCT00000041121.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055145.2", "url": "https://www.ensembl.org/id/ENSSSCP00000055145.2" } ] } }, { "isoform_ac": "A0A5G2QGU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7/entry#A0A5G2QGU8-1", "sequence": { "sequence": "MDLEKYMMFLEDMSQLILNEVPKADYDSLFNDFVESEFFLLDGDSLLIMCVCEKSLKQGQDLHFFYLVERYLVDLITKGGQFAVVFFKDAENTYFNLPELLPLRTALILHLQHNTNIDVRTDFSGCLSQEWEAFLEESYPYFLIVADEGLNNLQTHLFNFLIIQSWALKINAVLFAGQVADVLRLYAYFMPSRHKNQMFFQKNRRTIENAYRSLIKQLEKCRALAFAPLFGNLKWENMMEEAHETISLLKQLWPEGSDIRRVLCVTSCSLSLRFYHQLLESRSETTAAHQQVEGKPLALQEVEDLCKLHCLSVAFLLCLPLSQRACTRFVTSHWIEDIQTFLKMKKCCDYFILSDVNISESWNLDLTHLSDLSDELLLKNIAFYYENENAQGLHLGNVITKDYEHLWDTVSKLVRPFDVGKPFPLRTTKRPFLKKNPSPIKDTSMEKMPSLGFIPMSCQVVDNFVGDILKDLPFLTSDDPVVTSLVKQKEFDELVHWHSHKPLSDDYDRTKCQFNEKSRDPYYLRSVQKYHVFQRFYGNSLESVSSKFVVTQGIKPRKFYGPTSKKTQETKAEIITRENKKRLLAKEEEKEEKKWSVLSFSIEEEMKEDLNSGIKNLEDFLKSCKSSSVKFRVEMVGLTACLKAWKEYCQSEGETTKDLSIAVQMMKRIYSVVEKYPELLQEADRQVIAKCLRYLGFEELASSLHLTQRELLDVVDKNESAVIVAPTSSGKTYASYYCMERVLREGDDGVVVYVAPTKALVNQVAATVQNRFRKNLPDGEALCGVFTRDYRHDALNSQILITVPACFEILLLAPHRQAWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKQADERMGQNIASRSVGCRPGSRKDCLLAKQSYRVRLVLYGERYNDLEKHICSVNNGVISFNHFHPCAALTTDHIEKYGFPSDLTLSPREMVQLYDTMFHFWAGWPRAQELCPEEFIHFKNKIVIKKSDTRKYEESLKAELTDWVKSGCVKQARMVLKHLRPGSVISSENMADMFPLLVEKLKQMEKLPALFFLFKLGAVEERARSVKTFLEKKQQRKRPPKADKEAHDMENKLRKVRKSIEKQKTIDEKSLKKPRNMDQSLIHEAEHDNLLKVLEKNLEIPQDCTYADQKALDAQTLQTVFDRVKLTRKGAELKALAARGVGYHHSSLNFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSIYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIEKLIKSNVPQLRGQFPLSISLVLRLMLLASKGDDPGDAQAKVLSVLKHSLLSFKQPRTLEMLKLYFLFALQFLVKEGYLDREGNPVGFAGLVSHLHYHEPSNLVFVSFLVRGLFHNLCQPTRKGSKLFSQDVMEKLVLVLANLFGRTYFPAKFHESPPKFYQSKVFLEDLPKDFKDALDQYNKNVTEDFASFLMIVSRLADMKQEYQLPLSHTDFSGEECEDSQLASYLMSCKEGRVAISPFVCLSGNSDGDLLCPGTLDHVTLRTIGISSSQAPVLCPQRFDNQGRKMPLNAYALDFYKHGSLTGLVQDNRMNEGLAYQLLKDFALTIQSISVSLRELCVNEEDNVVLAFEQLSKSFLEKFNKI", "length": 1651, "header": "tr|A0A5G2QGU8-1|A0A5G2QRV7_PIG Computationally mapped isoform of DExD/H-box helicase 60 OS=Sus scrofa OX=9823 GN=DDX60 PE=1 SV=1 CANONICAL=A0A5G2QRV7-1" }, "locus": { "chromosome": "14", "start_pos": 21162923, "end_pos": 21089421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069544.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069544.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063539.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063539.1" } ] } }, { "isoform_ac": "A0A5G2QRV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7/entry#A0A5G2QRV7-1", "sequence": { "sequence": "MDLEKYMMFLEDMSQLILNEVPKADYDSLFNDFVESEFFLLDGDSLLIMCVCEKSLKQGQDLHFFYLVERYLVDLITKGGQFAVVFFKDAENTYFNLPELLPLRTALILHLQHNTNIDVRTDFSGCLSQEWEAFLEESYPYFLIVADEGLNNLQTHLFNFLIIQSWALKINAVLFAGQVADVLRLYAYFMPSRHKNQMFFQKNRRTIENAYRSLIKQLEKCRALAFAPLFGNLKWENMMEEAHETISLLKQLWPEGSDIRRVLCVTSCSLSLRFYHQLLESRSETTAAHQQVEGKPLALQEVEDLCKLHCLSVAFLLCLPLSQRACTRFVTSHWIEDIQTFLKMKKCCDYFILSDVNISESWNLDLTHLSDLSDELLLKNIAFYYENENAQGLHLGNVITKDYEHLWDTVSKLVRPFDVGKPFPLRTTKRPFLKKNPSPIKDTSMEKMPSLGFIPMSCQVVDNFVGDILKDLPFLTSDDPVVTSLVKQKEFDELVHWHSHKPLSDDYDRTKCQFNEKSRDPYYLRSVQKYHVFQRFYGNSLESVSSKFVVTQGIKPRKFYGPTSKKTQETKAEIITRENKKRLLAKEEEKEEKKWSVLSFSIEEEMKEDLNSGIKNLEDFLKSCKSSSVKFRVEMVGLTACLKAWKEYCQSEGETTKDLSIAVQMMKRIYSVVEKYPELLQEADRQVIAKCLRYLGFEELASSLHLTQVAGNVTKEKRKNKYSVGIGPARFQLQYMGPYLLRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMERVLREGDDGVVVYVAPTKALVNQVAATVQNRFRKNLPDGEALCGVFTRDYRHDALNSQILITVPACFEILLLAPHRQAWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKQADERMGQNIASRSVGCRPGSRKDCLLAKQSYRVRLVLYGERYNDLEKHICSVNNGVISFNHFHPCAALTTDHIEKYGFPSDLTLSPREMVQLYDTMFHFWAGWPRAQELCPEEFIHFKNKIVIKKSDTRKYEESLKAELTDWVKSGCVKQARMVLKHLRPGSVISSENMADMFPLLVEKLKQMEKLPALFFLFKLGAVEERARSVKTFLEKKQQRKRPPKADKEAHDMENKLRKVRKSIEKQKTIDEKSLKKPRNMDQSLIHEAEHDNLLKVLEKNLEIPQDCTYADQKALDAQTLQTVFDRVKLTRKGAELKALAARGVGYHHSSLNFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSIYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIEKLIKSNVPQLRGQFPLSISLVLRLMLLASKGDDPGDAQAKVLSVLKHSLLSFKQPRTLEMLKLYFLFALQFLVKEGYLDREGNPVGFAGLVSHLHYHEPSNLVFVSFLVRGLFHNLCQPTRKGSKLFSQDVMEKLVLVLANLFGRTYFPAKFHESPPKFYQSKVFLEDLPKDFKDALDQYNKNVTEDFASFLMIVSRLADMKQEYQLPLSHTDFSGEECEDSQLASYLMSCKEGRVAISPFVCLSGNSDGDLLCPGTLDHVTLRTIGISSSQAPVLCPQRFDNQGRKMPLNAYALDFYKHGSLTGLVQDNRMNEGLAYQLLKDFALTIQSISVSLRELCVNEEDNVVLAFEQLSKSFLEKFNKI", "length": 1704, "header": "tr|A0A5G2QRV7-1|A0A5G2QRV7_PIG Isoform 1 of DExD/H-box helicase 60 OS=Sus scrofa OX=9823 GN=DDX60 PE=1 SV=1 CANONICAL=A0A5G2QRV7-1" }, "locus": { "chromosome": "14", "start_pos": 21162923, "end_pos": 21089421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071910.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071910.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066827.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066827.1" } ] } }, { "isoform_ac": "A0A5G2R6W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7/entry#A0A5G2R6W4-1", "sequence": { "sequence": "MDLEKYMMFLEDMSQLILNEVPKADYDSLFNDFVESEFFLLDGDSLLIMCVCEKSLKQGQDLHFFYLVERYLVDLITKGGQFAVVFFKDAENTYFNLPELLPLRTALILHLQHNTNIDVRTDFSGCLSQEWEAFLEESYPYFLIVADEGLNNLQTHLFNFLIIQSWALKINAVLFAGQVADVLRLYAYFMPSRHKNQMFFQKNRRTIENAYRSLIKQLEKCRALAFAPLFGNLKWENMMEEAHETISLLKQLWPEGSDIRRVLCVTSCSLSLRFYHQLLESRSETTAAHQQVEGKPLALQEVEDLCKLHCLSVAFLLCLPLSQRACTRFVTSHWIEDIQTFLKMKKCCDYFILSDVNISESWNLDLTHLSDLSDELLLKNIAFYYENENAQGLHLGNVITKDYEHLWDTVSKLVRPFDVGKPFPLRTTKRPFLKKNPSPIKDTSMEKMPSLGFIPMSCQVVDNFVGDILKDLPFLTSDDPVVTSLVKQKEFDELVHWHSHKPLSDDYDRTKCQFNEKSRDPYYLRSVQKYHVFQRFYGNSLESVSSKFVVTQGIKPRKFYGPTSKKTQETKAEIITRENKKRLLAKEEEKEEKKWSVLSFSIEEEMKEDLNSGIKNLEDFLKSCKSSSVKFRVEMVGLTACLKAWKEYCQSEGETTKDLSIAVQMMKRIYSVVEKYPELLQEADRQVIAKCLRYLGFEELASSLHLTQVAGNVTKEKRKNKYSVGIGPARFQLQYMGPYLLRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMERVLREGDDGVVVYVAPTKALVNQVAATVQNRFRKNLPDGEALCGVFTRDYRHDALNSQILITVPACFEILLLAPHRQAWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKQADERMGQNIASRSVGCRPGSRKDCLLAKQSYRVRLVLYGERYNDLEKHICSVNNGVISFNHFHPCAALTTDHIEKYGFPSDLTLSPREMVQLYDTMFHFWAGWPRAQELCPEEFIHFKNKIVIKKSDTRKYEESLKAELTDWVKSGCVKQARMVLKHLRPGSVISSENMADMFPLLVEKLKQMEKLPALFFLFKLGAVEERARSVKTFLEKKQQRKRPPKADKEAHDMENKLRKVRKSIEKQKTIDEKSLKKPRNMDQSLIHEAEHDNLLKVLEKNLEIPQDCTYADQKALDAQTLQTVFDRVKLTRKGAELKALAARGVGYHHSSLNFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSIYLDALNYRQVLSVLKHSLLSFKQPRTLEMLKLYFLFALQFLVKEGYLDREGNPVGFAGLVSHLHYHEPSNLVFVSFLVRGLFHNLCQPTRKGSKLFSQDVMEKLVLVLANLFGRTYFPAKFHESPPKFYQSKVFLEDLPKDFKDALDQYNKNVTEDFASFLMIVSRLADMKQEYQLPLSHTDFSGEECEDSQLASYLMSCKEGRVAISPFVCLSGNSDGDLLCPGTLDHVTLRTIGISSSQAPVLCPQRFDNQGRKMPLNAYALDFYKHGSLTGLVQDNRMNEGLAYQLLKDFALTIQSISVSLRELCVNEEDNVVLAFEQLSKSFLEKFNKI", "length": 1637, "header": "tr|A0A5G2R6W4-1|A0A5G2QRV7_PIG Computationally mapped isoform of DExD/H-box helicase 60 OS=Sus scrofa OX=9823 GN=DDX60 PE=1 SV=1 CANONICAL=A0A5G2QRV7-1" }, "locus": { "chromosome": "14", "start_pos": 21162923, "end_pos": 21089421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082672.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082672.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066341.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066341.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QGU8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGU8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100158037", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158037", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K744-1", "protein_name": "DEXD/H-box helicase 60", "gene_name": "LOC134478918", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKRCTMFLEGMSQLILENIPRADYSSLFNDFVESEFFLIDGDSLLLTCVCEMSLEPGQSLHFFYLVERYLLDVTSKGGQFAIVFFKDAEYAYFSVPELLTLRTSLILHLQKNTTIEVWTMFSNCLSEEWSICLNQSCPYFLIVADEGLDHLQTHLLNFVVIQAWAAKVNVVLFSGQTSDILRLYAYFMQSSYTNQMFFKKNEETIMNVYKALIEQLEKYRDRALTPLFGDLKFNDMEKEVSEIVSLLKQLWPEGSDIRRVFCVTSCSLFLEMYHSYLENREKRASTETSEVTQKPDNCLTLKDVEDFCKLHCLSVAFQLHLPLSQRARSRFITSNWIQDLQTVLKMKEWCEYFTLNNVDIFEFWSLDLLHVSDLSDEPLLKNIAFYYEYENKGGLDLKVGDVIMKEYIHLWDTVSKLVKKFDVGKPTPLRTTKVHFIEKTLSPIKESSQETMPNLGFIPISCNLVDEFTRDILKDLPFLKSDDPIVTSLVKHKEFDELVHWHSHRPLSDDYDRTKATFDDKKDPYYLSRLQKYHRFQRLYGSSLESVTSKMITTEGPKPKKDCIKSKRTKAHKTKAEIIVRENKKRLIAEEEQKEGQKWSALSFSIEEEMRRNLNSGIKKLEEFLKSCKSSSVKTQAERVGLQACLKAWKEHCRAEGKTTKDFNIAVNMMKRIHSLLEKQSEFLQEADQKLIARCLTYLGFYELADSLCPTQDTADDVKMTKKKYSVGIGPARFQLQYMGHYLIREERKDPDPRVQDFIPDTWQRELLDVVDNYESAVIVAPTSSGKTYASYYCMEKVLKESNEGVVVYVAPTKALVNQVAATVQNRYTKNMPGGEALCGVFTRDYRHEALNSQVLITVPACFEILLLAPHRQNWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPQHLTEWLQSVKRYWKQVDSTMEQGSVSQRNAATRGSYHKDRVQARQSYKVRLVLYGERYNDLEKYLCSVRQGDVCFDHFHPCAALTTDHIEKYGFPSDLALSPRESIQLYDTMCQVWKSWPQAQNLCPENFTQFKNKIVIKKLDARKYEESLKEEFTNWVKNGNEKEAQLVLKKLSPDYHDYSGQMLDFFPCLVEKLRKMEKLPALFFLFSLDTVEECAENVCEFLEEKQEEKRPPKADKEAYIMANKLRKVKKSLEKQKIDEKGQKSSRRLDQSIMYEAEHNYLLKSLEKNLEIPKDCTYADQKAIDEETLQIVFGRVKCGKKGDTLKKLARRGIGYHHRSMTAKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIGKLIKSKVPELRGQFPLSITLILRLMLLATKADDLEDGKAKALSVLKHSLLSFKQPRATDMLKLYFLYSLQFLVKEGHIDQEGNPTGFAGLVTHLNYHEPSNLVFVSFLVKGLFHKLCQPTSKDSKCFSEDVMEKLVLVLANLFGRIYIPAKFYEVNTKFYQSKVFLDDLPQDFSDALLAYNMQVTRDFASFLLIVSRLADMKQEYQLPLSKIEFAGKECEDSPLVSHLMSCKEGRMAVSPFVCLSGNFDVDLLSPGVPNHVTLHTICINHAQAPVLWPHRLDSQGRKMPLNAYALDFYKHGSLTGLVQDNGIHPGDAYNLLKDFYLTIKSISVSLRELCENEEDNVVLAFEQLSKSFHEKFELV", "length": 1708 }, "evidence": [ { "id": "A0A5G2QRV7", "url": "https://omabrowser.org/oma/group/A0A5G2QRV7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7J8F2-1", "protein_name": "Probable ATP-dependent RNA helicase DDX60 isoform X1", "gene_name": "Ddx60", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASRMEKHPTVVLEELMSQLILEKMPKADYSSLFNDFVESEFFLIDGDSLFVTCLFEKSLKPGQSLHFFYLVERYLLDIISKGGQFAIVFFKDAEYAYFNVPALLTLRTALILHLQKNTTIDVQTKFSGCLSKDWSIFLNQSCPYFLILADEGLNNQQTHLFNFVVIQSWAEKINIVLFSGQTSDILRLYAYFMHSSYSEQKFYKENMNEIMIAYKGLIQHLEKHRDEHLTTLFGDLKFNNVMEKACETISRLTQLWPEGSDIRRVLCVTSCSLSLEMYHCFLENGEEKASKQTCEVKQEKGNCLTLKDVEDFCKLHCLSVVFQLHLPLSQRAQSRFITSGWIQDLKTVFKMKKWCEYFILSNLHTFELWSLNSLHLSDLSDEPLLKNIAFYYENENAQGLDLNVGDVIMKEYVHLWDTVSKLVRKFDVGKPFPVRTTKCHFLKKTPSPIKEISQEKMPNLGFIPMSCSLVDEFTGDILKDLPFLKSDDPIVTSLVKHKEFDELVHWHSHRPLSDDYDRTKASFDEHSRDPRQLRSLQKYQVFQRFYGNSLESVSSKIITTQSVKPKKDCSKSRSTKAHETKADIIARENKKRLIAKEEQKEEQKWNVLSSSIEKEMKRNLNSGMQKLEEFLKSCKSNSVKVQAEKVGLTACLTAWREHCRAEGETTKNLNIAIDMMKRIHSLLDKHSELLQEGDRKLIARCLKYLGFDELANSLYPTQDAVDDLKKTKKNKYSLGIGPARFQLQYMGHHLIREERKDPDPRVQDFIPDTWQRELLDVVDNYESAVIVAPTSSGKTYASYYCMEKVLKESNEGVVVYVAPTKALVNQVAATVQSRYTKILPTGGALCGVFTRDYRHDALNCQVLVTVPACFEILLLAPHRQSWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKKVDSEMGKLTFTKRNAGSRGSHHKDQVQARQSYKVRLVLYGERYNDLEKYLCSVRQDDVCFDHFHPCAALTTDHIEKYGFPSDLAFSPRESIQLYDTMLQVWKSWPQAQNLCPENFTHLKNKIVIKKSDAREYEKSLKEEFTNWVKNGNEEQARMVLQKLSPNFCDYSGQMLKFFPNLVEKLREMEKLPALFFLFRFASVEQCAEDACQFLEDKQDEKRPPNADKEAHVMAKKLRKVKKSLEKPQQIIYRLSSVEGGAEAACQFLEVQQEEKRPPNSDKEAHAMANKLQKVKKSLEKPQNIRDEKSKKPSRRLDQIIMHEAEYNYLLKSLEKHLEIPEDCTYADQKAIDDESLQMVFDRVKFQRKGNTLKKLARRGIGYHHSSMSFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFVQNSVYLDALNFRQMSGRAGRRGQDLLGDVYFFNIPLPKISKLIKSKVPELRGQFPLSISLILRLLLLASKADDLEDGKAKALSVLKHSLLSFKHPRVIDMLKLYFLYSLQFLVKEGHIDQEGNPTGFAGLVTHLHYHEPSNLVFVNFLVRGLFHNLCQPTHKGSKCFSKDVMEKLVLVLANLFGRRYLPAKFQDVNIKFYQSKVFLDDLPEDFNEALNEYNMKVTMDFAAFLLIVSRLADMKQEYQLPLSKIEFAGKECEDSPLVSHLMSCREGRVAVSPFVCLSGNFDEDLLHPGVSDNVVLHTIAVNHCQAPVLWPHRFDNTGRKMPLNAYALDFYKHGSLVGLVQDNGIHQGEAYHLLKDFFLTIKSISVSLRELCENEEDNVVLAFEQLVESFKEKFEKV", "length": 1771 }, "evidence": [ { "id": "A0A5G2QRV7", "url": "https://omabrowser.org/oma/group/A0A5G2QRV7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E9PZQ1-1", "protein_name": "DExD/H box helicase 60", "gene_name": "Ddx60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKKYTGFLKIMSHLILETMSKADYSSLFNDFVESEFFLIDGDSLLITCACERSLKPGQSLHFFYLVERYLLDVISKGGQFAIVFFKDAEYAYFNVPELLTLRTALILHLQKNTTVEVWTKFSNCLSEEWNICLGQSCPYFLILADEGLNDLQTHLFNFVVIQAWAAKVNIVLFSGQTSDILRLYAYFMQSSHGMQMFFKENKRMIMIVYKSLIQQLEKYRDMALAHLFGDLKFNDMEEKVCETVSLLKQLWPEGSDIRCVFCVTSCSLFLEMYHCYLESREKGASEEMSKVKQKTDNCLTLKDMEDFCKLHCLSVALLLHVPLSQRARSRFITANWIQDLKTVLKMKKWCEYFILSNLDMFESWSLNLLHLSDLSDEPLLRNIAFYYENENKEGLDLNVGDAIMNEYVHLWDTVSKLVRKFDVGKPIPLRTTKVHFLEKTPSPIKESSQEMMPNLGFIPMSCNLVDEFTGDILKDLPFLMSDDPIVTSLVKHKEFDELVHWHSHRPLSDDYDRTKCIGDANRRDPNHLKRLQKYHSFQRFYGESLESVTSKTITTQGPKPKKDCIKSKSTKAHETKAEIIKRENKKRLIAEEEQKEEQKWNALSFSIEEEMRKNVDSGMKKLEEFLKSCKSRSVKAQVERVGLQACLKAWKEHCQAEGETTKDLSIAVNMMKRIHSLLDKHSELLQEADQKLIARCLKYLGFCELAVSLYPTQDASDGIKMKKKNKYSVGIGPARFQLQYMGHYLIREERKDPDPRVQDFIPDTWQRELLDVVDNYESAVIVAPTSSGKTYASYYCMEKVLKESDEGVVVYVAPTKALVNQVAATVEYRYAKNMPAGESLCGVFTRDYRHDALNCQVLITVPACFEILLLAPHRQNWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPQHLTEWLQSVKRYWKQVDSTMEERTVSKRTGTSRGSYYKDQAQARQSYKVRLVLYGERYNDLEKYLCSVRQGDVCFDHFHPCAALTIDHIEKYGFPSDLALSPRESIQLYDTMCQVWKSWPQAQSLCPENFTQFKNKIVIKKLDARKYEESLKEEFTNWVKNGNEEEARMVLKKLSPDYHEHSGRMLDFFPCLVEKLRKMEKLPALFFLFKLNIVEECAENAFEFLEKKQEEKRPPKADKEARTTANKLRKVKKSLEKQKTVDEKGQKSSRRLDESVMHETEHNYLLQTLEKNLEIPKDCTYANQKAIDDQLLQRVFHRVRFERKGETLKRLAERGIGYHHSSMSAKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIGKLIKSKVPELRGQFPLSISLILRLMLLASKADDLEDGKAKALSVLKHSLLSFKQPRAIDMLKLYFLYSLQFLVKEGHIDQEGNPTGFAGLVSHLHYHEPSNLVFVSFLVKGLFHKLCQPTREGPKRFSEDVMEKLVLVLANLFGRRYIPAKFYEVNSKFYQSKVFLDDLPEDFSHALLEYNTQVTEDFASFLLMVSRLADMKQEYQLSLSKIEFTGKECEDSPLVSHLMNCKEGRVAVSPFVCLSGNFDVDLLSPGVPNHVILHTLGINHTQAPVLWPYALDSQGRKIPLNAYALDFYKHGSLIGLVQDNRIHPGEAYSLLKDFNLIIKSISVSLRELCENEEDNVVLAFEQLSTSFQEKFELV", "length": 1711 }, "evidence": [ { "id": "A0A5G2QRV7", "url": "https://omabrowser.org/oma/group/A0A5G2QRV7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IY21-1", "protein_name": "Probable ATP-dependent RNA helicase DDX60", "gene_name": "DDX60", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERNVLTTFSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQNLHFFYLVERYLVDLISKGGQFTIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVRTTFSRCLSKEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNVVLSSGQESDVLCLYAYLLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITEEAHKTVSLLTQVWPEGSDIRRVFCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCLTLQEMEDLCKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCEYFILRNIHTFEFWNLNLIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVRDFEVGQPFPLRTTKVCFLEKKPSPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFLKSDDPIVTSLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSVQKYHVFQRFYGNSLETVSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSIEEQLKENLHSGIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSIAVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLHPAQDAENDVKVKKRNKYSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAGFPKDYLQVKQSYKVRLVLYGERYNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFPPDLTLSPRESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKYEESLKAELTSWIKNGNVEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVENAAESVSTFLKKKQETKRPPKADKEAHVMANKLRKVKKSIEKQKIIDEKSQKKTRNVDQSLIHEAEHDNLVKCLEKNLEIPQDCTYADQKAVDTETLQKVFGRVKFERKGEELKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFFDIPFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNPMGFAGLVSHLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPKFQDAHFEFYQSKVFLDDLPEDFSDALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSKIKFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLGTIGVNRSQAPVLLSQKFDNRGRKMSLNAYALDFYKHGSLIGLVQDNRMNEGDAYYLLKDFALTIKSISVSLRELCENEDDNVVLAFEQLSTTFWEKLNKV", "length": 1712 }, "evidence": [ { "id": "A0A5G2QRV7", "url": "https://omabrowser.org/oma/group/A0A5G2QRV7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "pmid": "" }, { "name": "positive regulation of MDA-5 signaling pathway", "id": "GO:1900245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900245", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "pmid": "" }, { "name": "positive regulation of RIG-I signaling pathway", "id": "GO:1900246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900246", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1523, "end_pos": 1525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" }, { "start_pos": 771, "end_pos": 773, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 765, "end_pos": 932, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QRV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV7" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 1198, "end_pos": 1362, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1523, "end_pos": 1525 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 712, "end_pos": 714 }, { "start_pos": 771, "end_pos": 773 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQ26-1", "uniprot_ac": "A0A5G2QQ26", "uniprot_id": "A0A5G2QQ26_PIG", "mass": { "chemical_mass": 147268.0, "monoisotopic_mass": 147268.0 }, "refseq": {}, "gene_names": [ { "name": "GAK", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ] } ], "protein_names": [ { "name": "Cyclin-G-associated kinase", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A5G2QQ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26/entry#names_and_taxonomy" } ] }, { "name": "DnaJ homolog subfamily C member 26", "type": "synonym", "evidence": [ { "id": "A0A5G2QQ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. May play a role in clathrin-mediated endocytosis and intracellular trafficking, and in the dynamics of clathrin assembly/disassembly.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26#function" }, { "database": "UniProtKB", "id": "ARBA00054326", "url": "https://www.uniprot.org/uniprotkb/ARBA00054326#function" }, { "database": "UniProtKB", "id": "I3LQD7", "url": "https://www.uniprot.org/uniprotkb/I3LQD7#function" }, { "database": "UniProtKB", "id": "A0A5G2R4P6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4P6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GAK", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26", "locus": { "chromosome": "8", "start_pos": 240822, "end_pos": 296956, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021289", "url": "https://www.ensembl.org/id/ENSSSCG00000021289" } ] } } ], "crossref": [ { "id": "ENSSSCG00000021289", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000021289", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14036", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14036", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14564", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14564", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100625047", "url": "https://www.ncbi.nlm.nih.gov/gene/100625047", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22967", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22967", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22967:SF105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22967:SF105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23172", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23172", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23172:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23172:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287ADR9", "url": "https://www.uniprot.org/uniprotkb/A0A287ADR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ADR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLG1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ26-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4P6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LQD7", "url": "https://www.uniprot.org/uniprotkb/I3LQD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LQD7-1", "url": "https://www.uniprot.org/uniprotkb/I3LQD7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLLQSALDFLAGPGSLGGAAGRDQTDFVGQTVEMGELRLRVRRVLAEGGFAFVYEAQDLGSGREYALKRLLSNEEEKNRVIIQEVCFMVSFSGERSFLLCASLSGPRALGSRASVPGLLFSVSKLCPLRACRPPGPPCPSHLRVRCALGLPSRRPLVRLMHSPLTRHLQKKLSGHPNIVQFCSAASIGKEESDTGQAEFLLLTELCKGQLVEFLKKVESKGPLSCDTVLKIFYQTCRAVQHMHKQKPPIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQQRALVEEEITRNTTPMYRTPEIVDLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYVIPPDDTRYSVFHGLIRATLKVNPEERLSITELVNQLQEIAAARNVNPKSPITELLEQNGGCGSAAPPTGSASSGCSGGLAVAEYDQPYGGLLDILRGGTERLFTNIKDTSSKVIQSVASYAKGDLDISYITSRIAVMSFPAEGVESAIKNNVEDVRLFLDSKHPGRYTVYNLSPRTYRPSRFHSRVSECGWVARRAPSLHSLYSLCRSMHAWLRQDPKNVCVVHCMDGRAASAVAVCSFLCFCRLFSTAEAAVYMFSMKRCPPGIWPSHKRYIEYVCDMVAEEPITPHSKPVLVKAVAMTPVPLFSKQRHGCRPFCEVYVGDERVATTSQEYDKMRDFRVEDGKAVIPLDVAVQGDVLVVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKFPDLFQVHLEVEVEPRDRPSREAPPWESASMRGLNPKILFSSREEQQDVLSKFGKPELPRQPGSTAQYEAEGPGPDLPHSSADANHFLHTLDWQEDRDTTAGPEGHPAKEDPPAAAEDGRESEPSDEEATTLSAESGDTADEDAPGPAAPPEDSVDLLGLHAEAGPAPCPQARGGPPSNADLLSCLLGAPPPAPAGTTGRLLEGDTSLLFSSPAPPPSAPTAPREASAPAADPFDPLLLPSDPVSQPCSRPDLFGEFLTSDSPAGPPASFPSTHSAPPPACSSDFLRLGDLPTEPSRVTASTSHPDLLGGWDAWAEASAPTSATEGPFFSPGGQPAPPGPPASQPQSQNQDPFADLGDLSSSLQGSPAAPPPGGFGPKTGALPKASGSWQTSRPSAQGTSWHPQARPPPKATAQPRPNYTPGFSVIGSREERGVRAPGFGPRPRVSENDFEDLLSSQGFSSRADRRGPRTVAEMRRQDQARDTDPLKLKLQDWTEGKERNIRALLSTLHTVLWDGESRWTPVGMADLVTPGQVKKQYRRAVLVVHPDKAQGQPYEQHARLIFMELSDAWAEFESQGCRPLF", "length": 1352, "header": "tr|A0A5G2QQ26-1|A0A5G2QQ26_PIG Isoform 1 of Cyclin-G-associated kinase OS=Sus scrofa OX=9823 GN=GAK PE=1 SV=1 CANONICAL=A0A5G2QQ26-1" }, "isoforms": [ { "isoform_ac": "A0A287ADR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26/entry#A0A287ADR9-1", "sequence": { "sequence": "MFPFWTPQSTGGFAFVYEAQDLGSGREYALKRLLSNEEEKNRVIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDTGQAEFLLLTELCKGQLVEFLKKVESKGPLSCDTVLKIFYQTCRAVQHMHKQKPPIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQQRALVEEEITRNTTPMYRTPEIVDLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYVIPPDDTRYSVFHGLIRATLKVNPEERLSITELVNQLQEIAAARNVNPKSPITELLEQNGGCGSAAPPTGSASSGCSGGLAVAEYDQPYGGLLDILRGGTERLFTNIKDTSSKVIQSVASYAKGDLDISYITSRIAVMSFPAEGVESAIKNNVEDVRLFLDSKHPGRYTVYNLSPRTYRPSRFHSRVSECGWVARRAPSLHSLYSLCRSMHAWLRQDPKNVCVVHCMDGRAASAVAVCSFLCFCRLFSTAEAAVYMFSMKRCPPGIWPSHKRYIEYVCDMVAEEPITPHSKPVLVKAVAMTPVPLFSKQRHGCRPFCEVYVGDERVATTSQEYDKMRDFRVEDGKAVIPLDVAVQGDVLVVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKFPDLFQVHLEVEVEPRDRPSREAPPWESASMRGLNPKILFSSREEQQDVLSKFGKPELPRQPGSTAQYEAEGPGPDLPHSSADANHFLHTLDWQEDRDTTAGPEGHPAKEDPPAAAEDGRESEPSDEEATTLSAESGDTADEDAPGPAAPPEDSVDLLGLHAEAGPAPCPQARGGPPSNADLLSCLLGAPPPAPAGTTGRLLEGDTSLLFSSPAPPPSAPTAPREASAPAADPFDPLLLPSDPVSQPCSRPDLFGEFLTSDSPAGPPASFPSTHSAPPPACSSDFLRLGDLPTEPSRVTASTSHPDLLGGWDAWAEASAPTSATEGPFFSPGGQPAPPGPPASQPQSQNQDPFADLGDLSSSLQGIGRQTERQPSVGAEGLAHPATRKGRALGRGQCQPL", "length": 1052, "header": "tr|A0A287ADR9-1|A0A5G2QQ26_PIG Computationally mapped isoform of Cyclin-G-associated kinase OS=Sus scrofa OX=9823 GN=GAK PE=1 SV=2 CANONICAL=A0A5G2QQ26-1" }, "locus": { "chromosome": "8", "start_pos": 293270, "end_pos": 245495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053029.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053029.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042161.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042161.2" } ] } }, { "isoform_ac": "A0A5G2QLG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26/entry#A0A5G2QLG1-1", "sequence": { "sequence": "MFPFWTPQSTGGFAFVYEAQDLGSGREYALKRLLSNEEEKNRVIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDTGQAEFLLLTELCKGQLVEFLKKVESKGPLSCDTVLKIFYQTCRAVQHMHKQKPPIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQQRALVEEEITRNTTPMYRTPEIVDLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYVIPPDDTRYSVFHGLIRATLKVNPEERLSITELVNQLQEIAAARNVNPKSPITELLEQNGGCGSAAPPTGSASSGCSGGLAVAEYDQPYGGLLDILRGGTERLFTNIKDTSSKVIQSVASYAKGDLDISYITSRIAVMSFPAEGVESAIKNNVEDVRLFLDSKHPGRYTVYNLSPRTYRPSRFHSRVSECGWVARRAPSLHSLYSLCRSMHAWLRQDPKNVCVVHCMDGRAASAVAVCSFLCFCRLFSTAEAAVYMFSMKRCPPGIWPSHKRYIEYVCDMVAEEPITPHSKPVLVKAVAMTPVPLFSKQRHGCRPFCEVYVGDERVATTSQEYDKMRDFRVEDGKAVIPLDVAVQGDVLVVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKFPDLFQVHLEVEVEPRDRPSREAPPWESASMRGLNPKILFSSREEQQDVLSKFGKPELPRQPGSTAQYEAEGPGPDLPHSSADANHFLHTLDWQEDRDTTAGPEGHPAKEDPPAAAEDGRESEPSDEEATTLSAESGDTADEDAPGPAAPPEDSVDLLGLHAEAGPAPCPQARGGPPSNADLLSCLLGAPPPAPAGTTGRLLEGDTSLLFSSPAPPPSAPTAPREASAPAADPFDPLLLPSDPVSQPCSRPDLFGEFLTSDSPAGPPASFPSTHSAPPPACSSDFLRLGDLPTEPSRVTASTSHPDLLGGWDAWAEASAPTSATEGTARRDRCTPRKVGQTHILVGGLSIPLSTGIGRQTERQPSVGAEGLAHPATRKGRALGRGQCQPL", "length": 1042, "header": "tr|A0A5G2QLG1-1|A0A5G2QQ26_PIG Computationally mapped isoform of Cyclin-G-associated kinase OS=Sus scrofa OX=9823 GN=GAK PE=1 SV=1 CANONICAL=A0A5G2QQ26-1" }, "locus": { "chromosome": "8", "start_pos": 293270, "end_pos": 245495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078495.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078495.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064870.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064870.1" } ] } }, { "isoform_ac": "A0A5G2QQ26-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26/entry#A0A5G2QQ26-1", "sequence": { "sequence": "MSLLQSALDFLAGPGSLGGAAGRDQTDFVGQTVEMGELRLRVRRVLAEGGFAFVYEAQDLGSGREYALKRLLSNEEEKNRVIIQEVCFMVSFSGERSFLLCASLSGPRALGSRASVPGLLFSVSKLCPLRACRPPGPPCPSHLRVRCALGLPSRRPLVRLMHSPLTRHLQKKLSGHPNIVQFCSAASIGKEESDTGQAEFLLLTELCKGQLVEFLKKVESKGPLSCDTVLKIFYQTCRAVQHMHKQKPPIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQQRALVEEEITRNTTPMYRTPEIVDLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYVIPPDDTRYSVFHGLIRATLKVNPEERLSITELVNQLQEIAAARNVNPKSPITELLEQNGGCGSAAPPTGSASSGCSGGLAVAEYDQPYGGLLDILRGGTERLFTNIKDTSSKVIQSVASYAKGDLDISYITSRIAVMSFPAEGVESAIKNNVEDVRLFLDSKHPGRYTVYNLSPRTYRPSRFHSRVSECGWVARRAPSLHSLYSLCRSMHAWLRQDPKNVCVVHCMDGRAASAVAVCSFLCFCRLFSTAEAAVYMFSMKRCPPGIWPSHKRYIEYVCDMVAEEPITPHSKPVLVKAVAMTPVPLFSKQRHGCRPFCEVYVGDERVATTSQEYDKMRDFRVEDGKAVIPLDVAVQGDVLVVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKFPDLFQVHLEVEVEPRDRPSREAPPWESASMRGLNPKILFSSREEQQDVLSKFGKPELPRQPGSTAQYEAEGPGPDLPHSSADANHFLHTLDWQEDRDTTAGPEGHPAKEDPPAAAEDGRESEPSDEEATTLSAESGDTADEDAPGPAAPPEDSVDLLGLHAEAGPAPCPQARGGPPSNADLLSCLLGAPPPAPAGTTGRLLEGDTSLLFSSPAPPPSAPTAPREASAPAADPFDPLLLPSDPVSQPCSRPDLFGEFLTSDSPAGPPASFPSTHSAPPPACSSDFLRLGDLPTEPSRVTASTSHPDLLGGWDAWAEASAPTSATEGPFFSPGGQPAPPGPPASQPQSQNQDPFADLGDLSSSLQGSPAAPPPGGFGPKTGALPKASGSWQTSRPSAQGTSWHPQARPPPKATAQPRPNYTPGFSVIGSREERGVRAPGFGPRPRVSENDFEDLLSSQGFSSRADRRGPRTVAEMRRQDQARDTDPLKLKLQDWTEGKERNIRALLSTLHTVLWDGESRWTPVGMADLVTPGQVKKQYRRAVLVVHPDKAQGQPYEQHARLIFMELSDAWAEFESQGCRPLF", "length": 1352, "header": "tr|A0A5G2QQ26-1|A0A5G2QQ26_PIG Isoform 1 of Cyclin-G-associated kinase OS=Sus scrofa OX=9823 GN=GAK PE=1 SV=1 CANONICAL=A0A5G2QQ26-1" }, "locus": { "chromosome": "8", "start_pos": 296854, "end_pos": 241199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083246.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083246.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066825.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066825.2" } ] } }, { "isoform_ac": "A0A5G2R4P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26/entry#A0A5G2R4P6-1", "sequence": { "sequence": "MISAHRDSFTSSFPDLGSGREYALKRLLSNEEEKNRVIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDTGQAEFLLLTELCKGQLVEFLKKVESKGPLSCDTVLKIFYQTCRAVQHMHKQKPPIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQQRALVEEEITRNTTPMYRTPEIVDLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYVIPPDDTRYSVFHGLIRATLKVNPEERLSITELVNQLQEIAAARNVNPKSPITELLEQNGGCGSAAPPTGSASSGCSGGLAVAEYDQPYGGLLDILRGGTERLFTNIKDTSSKVIQSVASYAKGDLDISYITSRIAVMSFPAEGVESAIKNNVEDVRLFLDSKHPGRYTVYNLSPRTYRPSRFHSRVSECGWVARRAPSLHSLYSLCRSMHAWLRQDPKNVCVVHCMDGRAASAVAVCSFLCFCRLFSTAEAAVYMFSMKRCPPGIWPSHKRYIEYVCDMVAEEPITPHSKPVLVKAVAMTPVPLFSKQRHGCRPFCEVYVGDERVATTSQEYDKMRDFRVEDGKAVIPLDVAVQGDVLVVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKFPDLFQVHLEVEVEPRDRPSREAPPWESASMRGLNPKILFSSREEQQDVLSKFGKPELPRQPGSTAQYEAEGPGPDLPHSSADANHFLHTLDWQEDRDTTAGPEGHPAKEDPPAAAEDGRESEPSDEEATTLSAESGDTADEDAPGPAAPPEDSVDLLGLHAEAGPAPCPQARGGPPSNADLLSCLLGAPPPAPAGTTGRLLEGDTSLLFSSPAPPPSAPTAPREASAPAADPFDPLLLPSDPVSQPCSRPDLFGEFLTSDSPAGPPASFPSTHSAPPPACSSDFLRLGDLPTEPSRVTASTSHPDLLGGWDAWAEASAPTSATEGPFFSPGGQPAPPGPPASQPQSQNQDPFADLGDLSSSLQGSPAAPPPGGFGPKTGALPKASGSWQTSRPSAQGTSWHPQARPPPKATAQPRPNYTPGFSVIGSREERGVRAPGFGPRPRVSENDFEDLLSSQGFSSRADRRGPRTVAEMRRQDQARDTDPLKLKLQDWTEGKERNIRALLSTLHTVLWDGESRWTPVGMADLVTPGQVKKQYRRAVLVVHPDKAQGQPYEQHARLIFMELSDAWAEFESQGCRPLF", "length": 1227, "header": "tr|A0A5G2R4P6-1|A0A5G2QQ26_PIG Computationally mapped isoform of Cyclin-G-associated kinase OS=Sus scrofa OX=9823 GN=GAK PE=1 SV=2 CANONICAL=A0A5G2QQ26-1" }, "locus": { "chromosome": "8", "start_pos": 281313, "end_pos": 241199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090161.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090161.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071308.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071308.2" } ] } }, { "isoform_ac": "I3LQD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26/entry#I3LQD7-1", "sequence": { "sequence": "MFPFWTPQSTGGFAFVYEAQDLGSGREYALKRLLSNEEEKNRVIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDTGQAEFLLLTELCKGQLVEFLKKVESKGPLSCDTVLKIFYQTCRAVQHMHKQKPPIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQQRALVEEEITRNTTPMYRTPEIVDLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYVIPPDDTRYSVFHGLIRATLKVNPEERLSITELVNQLQEIAAARNVNPKSPITELLEQNGGCGSAAPPTGSASSGCSGGLAVAEYDQPYGGLLDILRGGTERLFTNIKDTSSKVIQSVASYAKGDLDISYITSRIAVMSFPAEGVESAIKNNVEDVRLFLDSKHPGRYTVYNLSPRTYRPSRFHSRVSECGWVARRAPSLHSLYSLCRSMHAWLRQDPKNVCVVHCMDGRAASAVAVCSFLCFCRLFSTAEAAVYMFSMKRCPPGIWPSHKRYIEYVCDMVAEEPITPHSKPVLVKAVAMTPVPLFSKQRHGCRPFCEVYVGDERVATTSQEYDKMRDFRVEDGKAVIPLDVAVQGDVLVVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKFPDLFQVHLEVEVEPRDRPSREAPPWESASMRGLNPKILFSSREEQQDVLSKFGKPELPRQPGSTAQYEAEGPGPDLPHSSADANHFLHTLDWQEDRDTTAGPEGHPAKEDPPAAAEDGRESEPSDEEATTLSAESGDTADEDAPGPAAPPEDSVDLLGLHAEAGPAPCPQARGGPPSNADLLSCLLGAPPPAPAGTTGRLLEGDTSLLFSSPAPPPSAPTAPREASAPAADPFDPLLLPSDPVSQPCSRPDLFGEFLTSDSPAGPPASFPSTHSAPPPACSSDFLRLGDLPTEPSRVTASTSHPDLLGGWDAWAEASAPTSATEGPFFSPGGQPAPPGPPASQPQSQNQDPFADLGDLSSSLQGSPAAPPPGGFGPKTGALPKASGSWQTSRPSAQGTSWHPQARPPPKATAQPRPNYTPGFSVIGSREERGVRAPGFGPRPRVSENDFEDLLSSQGFSSRADRRGPRTVAEMRRQDQARDTDPLKLKLQDWTEGKERNIRALLSTLHTVLWDGESRWTPVGMADLVTPGQVKKQYRRAVLVVHPDKAQGQPYEQHARLIFMELSDAWAEFESQGCRPLF", "length": 1233, "header": "tr|I3LQD7-1|A0A5G2QQ26_PIG Computationally mapped isoform of Cyclin-G-associated kinase OS=Sus scrofa OX=9823 GN=GAK PE=1 SV=3 CANONICAL=A0A5G2QQ26-1" }, "locus": { "chromosome": "8", "start_pos": 293270, "end_pos": 241199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030183.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030183.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026316.3", "url": "https://www.ensembl.org/id/ENSSSCP00000026316.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QLG1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLG1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" }, { "id": "R-SSC-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "clathrin coat assembly", "id": "GO:0048268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048268", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "Golgi to lysosome transport", "id": "GO:0090160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090160", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "protein localization to Golgi apparatus", "id": "GO:0034067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034067", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "clathrin coat disassembly", "id": "GO:0072318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072318", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" }, { "name": "regulation of clathrin coat assembly", "id": "GO:1905443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905443", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1189, "end_pos": 1191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-SSC-421831", "name": "trans-Golgi Network Coat Assembly", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane, cytosol", "input_participant_list": [ "R-SSC-182958", "R-SSC-2213180" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-421831", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-421831" } ] }, { "id": "R-SSC-421835", "name": "trans-Golgi Network Vesicle Scission", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-421835", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-421835" } ] }, { "id": "R-SSC-8868658", "name": "HSPA8-mediated ATP hydrolysis promotes vesicle uncoating", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "clathrin-coated endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8868658", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8868658" } ] }, { "id": "R-SSC-8868659", "name": "Clathrin recruits auxilins to the clathrin-coated vesicle", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "clathrin-coated endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8868659", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8868659" } ] }, { "id": "R-SSC-8868660", "name": "Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "clathrin-coated endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8868660", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8868660" } ] }, { "id": "R-SSC-8871194", "name": "RAB5 and GAPVD1 bind AP-2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "clathrin-coated endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8871194", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8871194" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-182958", "participant_name": "SH3GL2 [cytosol]", "crossref": [ { "id": "A0A8D1Y277", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000005177", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000060026", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000084760", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-2213180", "participant_name": "DNM2 [cytosol]", "crossref": [ { "id": "A0A287B8X7", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000013630", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000052945", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000060743", "database": "ENSEMBL", "url": "" }, { "id": "XP_020939463.1", "database": "RefSeq", "url": "" }, { "id": "87381", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" }, { "id": "PS51182", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51182" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 tensin-type", "eco_id": "ECO_0000259", "start_pos": 647, "end_pos": 785, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QQ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 1288, "end_pos": 1352, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QQ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" }, { "id": "PS51181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatase tensin-type", "eco_id": "ECO_0000259", "start_pos": 474, "end_pos": 641, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QQ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ26" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 398, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1189, "end_pos": 1191 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 529, "end_pos": 531 }, { "start_pos": 752, "end_pos": 754 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QU82-1", "uniprot_ac": "A0A5G2QU82", "uniprot_id": "A0A5G2QU82_PIG", "mass": { "chemical_mass": 132291.0, "monoisotopic_mass": 132291.0 }, "refseq": {}, "gene_names": [ { "name": "GRID2IP", "type": "recommended", "evidence": [ { "id": "A0A5G2QU82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82" } ] } ], "protein_names": [ { "name": "Delphilin", "type": "recommended", "evidence": [ { "id": "A0A5G2QU82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82/entry#names_and_taxonomy" } ] }, { "name": "Glutamate receptor, ionotropic, delta 2-interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A5G2QU82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GRID2IP", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82", "locus": { "chromosome": "3", "start_pos": 4700037, "end_pos": 4667916, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037070", "url": "https://www.ensembl.org/id/ENSSSCG00000037070" } ] } } ], "crossref": [ { "id": "A0A5G2QU82", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU82", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000037070", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037070", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06743", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06743", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06744", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06744", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07354", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07354", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07355", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07355", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45725", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45725", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45725:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45725:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AGA1", "url": "https://www.uniprot.org/uniprotkb/A0A287AGA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AGA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AGA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QU82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QU82-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATTAMPATNQGWPEDFGFRLGGSGPCFVLEVAEGSSAHAGGLRPGDQILEIEGLAVGGLSRERLVRLARRCPRVPPSLGVLPGPDSCPGAVSGCGPPTTACRALRSGRGLSLGRELLRLAGRKRPDAVHRERRRKAQDFSRKVDEILGDQPAAKEQVFTALKQFAAEQRVDTLVWALTLALPPEACGPLLENLRIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKAASLPGGRPGPGGARRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPADNASLKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFASDSDSMDSPNPSSALTSLQWVAEILPSSIRVQGRTFSQQLEHLLTPPERYGVCRALESFFQHRTIDTLIVDVYPVLDTPAKQVLWQFIYQLLTYEEQELCQEKIACFLGYTAMTAEPEPELDLEPEPEPVPEPQPRSSLRASSMCRRSLRSQGLEASLGCGPSDCPDMPLPLIPGERQAGDGTSLPETPNPKMMSAVYAELESRLSSSFKGKMGTTSRSRASPPVPSTAGTAGPRNLSSVSWPSEQLLPSPCYYPLCSEGLASPSSSESHPYASLDSSRAPSPQPGPGPVCSDSPPSPDPGRPPSRRKLFTFSRPVRSRDTDRFLDALSEQLGPRVTIVDDFLSPENDYEEMSFHDDQGSFVTNERSSASECISSSEEGSSLTYSSISDHIPPPPLSPPPPLPFHDPKPSSRTPDGPRGPAPTLAKPLTQLSHPVPPPPPPPLPPPVPCAPPMLSRGLGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPAKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTSDLADLHGTIGEIQAACQSMSPSSEDKFAVVMASFLETAQPVLRALDGLQHEAMEELGKALAFFGEDSKATTSEAFFGIFAEFMSKFERALSDLQAGEGMRSSGMVSPLAW", "length": 1211, "header": "tr|A0A5G2QU82-1|A0A5G2QU82_PIG Isoform 1 of Delphilin OS=Sus scrofa OX=9823 GN=GRID2IP PE=4 SV=2 CANONICAL=A0A5G2QU82-1" }, "isoforms": [ { "isoform_ac": "A0A287AGA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82/entry#A0A287AGA1-1", "sequence": { "sequence": "MSCLGIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKAASLPGGRPGPGGARRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPADNASLKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFASDSDSMDSPNPSSALTSLQWVAEILPSSIRVQGRTFSQQLEHLLTPPERYGVCRALESFFQHRTIDTLIVDVYPVLDTPAKQVLWQFIYQLLTYEEQELCQEKIACFLGYTAMTAEPEPELDLEPEPEPVPEPQPRSSLRASSMCRRSLRSQGLEASLGCGPSDCPDMPLPLIPGERQAGDGTSLPETPNPKMMSAVYAELESRLSSSFKGKMGTTSRSRASPPVPSTAGTAGPRNLSSVSWPSEQLLPSPCYYPLCSEGLASPSSSESHPYASLDSSRAPSPQPGPGPVCSDSPPSPDPGRPPSRRKLFTFSRPVRSRDTDRFLDALSEQLGPRVTIVDDFLSPENDYEEMSFHDDQGSFVTNERSSASECISSSEEGSSLTYSSISDHIPPPPLSPPPPLPFHDPKPSSRTPDGPRGPAPTLAKPLTQLSHPVPPPPPPPLPPPVPCAPPMLSRGLGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPAKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTSDLADLHGTIGEIQAACQSMSPSSEDKFAVVMASFLETAQPVLRALDGLQHEAMEELGKALAFFGEDSKATTSEAFFGIFAEFMSKFERALSDLQAGEGMRSSGMVSPLAW", "length": 1021, "header": "tr|A0A287AGA1-1|A0A5G2QU82_PIG Computationally mapped isoform of Delphilin OS=Sus scrofa OX=9823 GN=GRID2IP PE=4 SV=3 CANONICAL=A0A5G2QU82-1" }, "locus": { "chromosome": "3", "start_pos": 4698686, "end_pos": 4676384, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054299.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054299.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043008.3", "url": "https://www.ensembl.org/id/ENSSSCP00000043008.3" } ] } }, { "isoform_ac": "A0A5G2QU82-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82/entry#A0A5G2QU82-1", "sequence": { "sequence": "MATTAMPATNQGWPEDFGFRLGGSGPCFVLEVAEGSSAHAGGLRPGDQILEIEGLAVGGLSRERLVRLARRCPRVPPSLGVLPGPDSCPGAVSGCGPPTTACRALRSGRGLSLGRELLRLAGRKRPDAVHRERRRKAQDFSRKVDEILGDQPAAKEQVFTALKQFAAEQRVDTLVWALTLALPPEACGPLLENLRIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKAASLPGGRPGPGGARRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPADNASLKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFASDSDSMDSPNPSSALTSLQWVAEILPSSIRVQGRTFSQQLEHLLTPPERYGVCRALESFFQHRTIDTLIVDVYPVLDTPAKQVLWQFIYQLLTYEEQELCQEKIACFLGYTAMTAEPEPELDLEPEPEPVPEPQPRSSLRASSMCRRSLRSQGLEASLGCGPSDCPDMPLPLIPGERQAGDGTSLPETPNPKMMSAVYAELESRLSSSFKGKMGTTSRSRASPPVPSTAGTAGPRNLSSVSWPSEQLLPSPCYYPLCSEGLASPSSSESHPYASLDSSRAPSPQPGPGPVCSDSPPSPDPGRPPSRRKLFTFSRPVRSRDTDRFLDALSEQLGPRVTIVDDFLSPENDYEEMSFHDDQGSFVTNERSSASECISSSEEGSSLTYSSISDHIPPPPLSPPPPLPFHDPKPSSRTPDGPRGPAPTLAKPLTQLSHPVPPPPPPPLPPPVPCAPPMLSRGLGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPAKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTSDLADLHGTIGEIQAACQSMSPSSEDKFAVVMASFLETAQPVLRALDGLQHEAMEELGKALAFFGEDSKATTSEAFFGIFAEFMSKFERALSDLQAGEGMRSSGMVSPLAW", "length": 1211, "header": "tr|A0A5G2QU82-1|A0A5G2QU82_PIG Isoform 1 of Delphilin OS=Sus scrofa OX=9823 GN=GRID2IP PE=4 SV=2 CANONICAL=A0A5G2QU82-1" }, "locus": { "chromosome": "3", "start_pos": 4698686, "end_pos": 4667916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090829.3", "url": "https://www.ensembl.org/id/ENSSSCT00000090829.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068408.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068408.2" } ] } }, { "isoform_ac": "A0A5G2QYU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82/entry#A0A5G2QYU7-1", "sequence": { "sequence": "MGKDQGFSRHFRIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKAASLPGGRPGPGGARRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPADNASLKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFASDSDSMDSPNPSSALTSLQWVAEILPSSIRVQGRTFSQQLEHLLTPPERYGVCRALESFFQHRTIDTLIVDVYPVLDTPAKQVLWQFIYQLLTYEEQELCQEKIACFLGYTAMTAEPEPELDLEPEPEPVPEPQPRSSLRASSMCRRSLRSQGLEASLGCGPSDCPDMPLPLIPGERQAGDGTSLPETPNPKMMSAVYAELESRLSSSFKGKMGTTSRSRASPPVPSTAGTAGPRNLSSVSWPSEQLLPSPCYYPLCSEGLASPSSSESHPYASLDSSRAPSPQPGPGPVCSDSPPSPDPGRPPSRRKLFTFSRPVRSRDTDRFLDALSEQLGPRVTIVDDFLSPENDYEEMSFHDDQGSFVTNERSSASECISSSEEGSSLTYSSISDHIPPPPLSPPPPLPFHDPKPSSRTPDGPRGPAPTLAKPLTQLSHPVPPPPPPPLPPPVPCAPPMLSRGLGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPAKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTSDLADLHGTIGEIQAACQSMSPSSEDKFAVVMASFLETAQPVLRALDGLQHEAMEELGKALAFFGEDSKATTSEAFFGIFAEFMSKFERALSDLQAGEGMRSSGMVSPLAW", "length": 1028, "header": "tr|A0A5G2QYU7-1|A0A5G2QU82_PIG Computationally mapped isoform of Delphilin OS=Sus scrofa OX=9823 GN=GRID2IP PE=4 SV=2 CANONICAL=A0A5G2QU82-1" }, "locus": { "chromosome": "3", "start_pos": 4698686, "end_pos": 4680586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080243.3", "url": "https://www.ensembl.org/id/ENSSSCT00000080243.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067113.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067113.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82" } ], "pmid": "" }, { "name": "postsynaptic density, intracellular component", "id": "GO:0099092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099092", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82" } ], "pmid": "" }, { "name": "parallel fiber to Purkinje cell synapse", "id": "GO:0098688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098688", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82" } ], "pmid": "" }, { "name": "cerebellar granule cell to Purkinje cell synapse", "id": "GO:0150048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150048", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of postsynaptic membrane neurotransmitter receptor levels", "id": "GO:0099072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099072", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82" } ], "pmid": "" }, { "name": "regulation of postsynaptic cytosolic calcium ion concentration", "id": "GO:0099566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099566", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1038, "end_pos": 1040, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1052, "end_pos": 1054, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 902, "end_pos": 904, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QU82-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1211, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QU82-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU82" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QU82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82" }, { "id": "PS51444", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51444" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FH2", "eco_id": "ECO_0000259", "start_pos": 820, "end_pos": 1211, "start_aa": "His", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QU82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU82" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 71, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1038, "end_pos": 1040 }, { "start_pos": 1052, "end_pos": 1054 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 902, "end_pos": 904 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQ93-1", "uniprot_ac": "A0A5G2QQ93", "uniprot_id": "A0A5G2QQ93_PIG", "mass": { "chemical_mass": 99462.0, "monoisotopic_mass": 99462.0 }, "refseq": {}, "gene_names": [ { "name": "TRPC7", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93" } ] } ], "protein_names": [ { "name": "Transient receptor potential cation channel subfamily C member 7", "type": "synonym", "evidence": [ { "id": "A0A5G2QQ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TRPC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93", "locus": { "chromosome": "2", "start_pos": 138373189, "end_pos": 138510728, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014318", "url": "https://www.ensembl.org/id/ENSSSCG00000014318" } ] } } ], "crossref": [ { "id": "A0A5G2QQ93", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ93", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014318", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014318", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005463", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005463", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CLECMEK", "url": "https://omabrowser.org/oma/group/CLECMEK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10117:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10117:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114508", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114508", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-139853", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-139853", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AMW4", "url": "https://www.uniprot.org/uniprotkb/A0A287AMW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AMW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q6X4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q6X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6X4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ93-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RH97", "url": "https://www.uniprot.org/uniprotkb/F1RH97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RH97-1", "url": "https://www.uniprot.org/uniprotkb/F1RH97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGSSTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSLGLPFLAVAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMEWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKASEAQLYVDQHVQDDTLQNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFRKTRYQAGMRNSENLTANNTFSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNKGKDI", "length": 862, "header": "tr|A0A5G2QQ93-1|A0A5G2QQ93_PIG Isoform 1 of Transient receptor potential cation channel subfamily C member 7 OS=Sus scrofa OX=9823 GN=TRPC7 PE=4 SV=1 CANONICAL=A0A5G2QQ93-1" }, "isoforms": [ { "isoform_ac": "A0A287AMW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93/entry#A0A287AMW4-1", "sequence": { "sequence": "MLGSSTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMEWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKASEAQLYVDQHVQDDTLQNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFRKTRYQAGMRNSENLTANNTFSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNKGKDI", "length": 807, "header": "tr|A0A287AMW4-1|A0A5G2QQ93_PIG Computationally mapped isoform of Transient receptor potential cation channel subfamily C member 7 OS=Sus scrofa OX=9823 GN=TRPC7 PE=4 SV=2 CANONICAL=A0A5G2QQ93-1" }, "locus": { "chromosome": "2", "start_pos": 138510536, "end_pos": 138373975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051492.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051492.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045263.2", "url": "https://www.ensembl.org/id/ENSSSCP00000045263.2" } ] } }, { "isoform_ac": "A0A5G2Q6X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93/entry#A0A5G2Q6X4-1", "sequence": { "sequence": "MAEFPQEGRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSLGLPFLAVAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMEWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKASEAQLYVDQHVQDDTLQNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFRNISSQRGSRPGSFNPFLVSTFQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNKGKDI", "length": 854, "header": "tr|A0A5G2Q6X4-1|A0A5G2QQ93_PIG Computationally mapped isoform of Transient receptor potential cation channel subfamily C member 7 OS=Sus scrofa OX=9823 GN=TRPC7 PE=4 SV=1 CANONICAL=A0A5G2QQ93-1" }, "locus": { "chromosome": "2", "start_pos": 138503116, "end_pos": 138373975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071039.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071039.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059783.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059783.1" } ] } }, { "isoform_ac": "A0A5G2QLF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93/entry#A0A5G2QLF0-1", "sequence": { "sequence": "MLGSSTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSLGLPFLAVAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMEWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKASEAQLYVDQHVQDDTLQNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFRKTRYQAGMRNSENLTANNTFSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNKGKDI", "length": 801, "header": "tr|A0A5G2QLF0-1|A0A5G2QQ93_PIG Computationally mapped isoform of Transient receptor potential cation channel subfamily C member 7 OS=Sus scrofa OX=9823 GN=TRPC7 PE=4 SV=1 CANONICAL=A0A5G2QQ93-1" }, "locus": { "chromosome": "2", "start_pos": 138510536, "end_pos": 138373975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084266.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084266.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065656.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065656.1" } ] } }, { "isoform_ac": "A0A5G2QQ93-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93/entry#A0A5G2QQ93-1", "sequence": { "sequence": "MLGSSTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSLGLPFLAVAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMEWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKASEAQLYVDQHVQDDTLQNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFRKTRYQAGMRNSENLTANNTFSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNKGKDI", "length": 862, "header": "tr|A0A5G2QQ93-1|A0A5G2QQ93_PIG Isoform 1 of Transient receptor potential cation channel subfamily C member 7 OS=Sus scrofa OX=9823 GN=TRPC7 PE=4 SV=1 CANONICAL=A0A5G2QQ93-1" }, "locus": { "chromosome": "2", "start_pos": 138510536, "end_pos": 138373975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076459.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076459.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066897.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066897.1" } ] } }, { "isoform_ac": "A0A5G2QXS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93/entry#A0A5G2QXS0-1", "sequence": { "sequence": "MLGSSTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMEWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKASEAQLYVDQHVQDDTLQNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFRKTRYQAGMRNSENLTANNTFSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNKGKDI", "length": 746, "header": "tr|A0A5G2QXS0-1|A0A5G2QQ93_PIG Computationally mapped isoform of Transient receptor potential cation channel subfamily C member 7 OS=Sus scrofa OX=9823 GN=TRPC7 PE=4 SV=1 CANONICAL=A0A5G2QQ93-1" }, "locus": { "chromosome": "2", "start_pos": 138510536, "end_pos": 138373975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067466.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067466.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068942.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068942.1" } ] } }, { "isoform_ac": "F1RH97-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93/entry#F1RH97-1", "sequence": { "sequence": "MLGSSTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSLGLPFLAVAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMEWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKASEAQLYVDQHVQDDTLQNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFRTRYQAGMRNSENLTANNTFSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNKGKDI", "length": 861, "header": "tr|F1RH97-1|A0A5G2QQ93_PIG Computationally mapped isoform of Transient receptor potential cation channel subfamily C member 7 OS=Sus scrofa OX=9823 GN=TRPC7 PE=4 SV=3 CANONICAL=A0A5G2QQ93-1" }, "locus": { "chromosome": "2", "start_pos": 138502453, "end_pos": 138373975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015644.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015644.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015231.3", "url": "https://www.ensembl.org/id/ENSSSCP00000015231.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2Q6X4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6X4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114508", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114508", "resource": "Reactome", "description": "Effects of PIP2 hydrolysis" }, { "id": "R-SSC-139853", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-139853", "resource": "Reactome", "description": "Elevation of cytosolic Ca2+ levels" }, { "id": "R-SSC-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LTG6-1", "protein_name": "Transient receptor potential cation channel subfamily C member 7", "gene_name": "TRPC7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFGSSTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILSHPAFAQGQRLALSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSLGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKASEAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFRKTRYQAGMRNSENLTANNTYSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNKGKDI", "length": 862 }, "evidence": [ { "id": "A0A5G2QQ93", "url": "https://omabrowser.org/oma/group/A0A5G2QQ93/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0Z017-1", "protein_name": "Transient receptor potential cation channel subfamily C member 7", "gene_name": "TRPC7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLRNSNYKNMHRRHTTLREKGRRQAIRGPAYMFNEKGTSLTAEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECIEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNIHLCPEHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKNLPNETITDHPKQIFRVKTTQFSWTELLIMKWVLGMIWSECKEIWEEGPREYVVHLWNLLDFGMLSIFVASFTARFMAFLKATEAQQYVDQYVQDDDLNNVTLPPEVAYFTYARNKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFLAFMIGMFNLYSYYLGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLILRIKMCLIKLCKSKAKNCENDLEMGMLNSKQRKVRFQSSSLHTENFSVKNAYNKPTRYQVPTLPPSGFYYLGHLQHTKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELARLIQQLSDKFGKNLNKDI", "length": 871 }, "evidence": [ { "id": "A0A5G2QQ93", "url": "https://omabrowser.org/oma/group/A0A5G2QQ93/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1LQF7-1", "protein_name": "Transient receptor potential cation channel, subfamily C, member 7", "gene_name": "Trpc7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVSHTDASPSHSLGNFPQIRKRTGRQVGHRRRVFTHKGKQSAPPHNRNSALWSRSRLQHHGERHLLLGHPWGARSPRLRTGFRSSRGGTSLRILLSMLGSNTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILSHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNLQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSVFVASFTARFMAFLKASEAQLYVDQYVQDVTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKRCENDLEMGMLNSKFRTRYQAGMRNSENLTANSTFSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNKGKDI", "length": 958 }, "evidence": [ { "id": "A0A5G2QQ93", "url": "https://omabrowser.org/oma/group/A0A5G2QQ93/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9HCX4-1", "protein_name": "Short transient receptor potential channel 7", "gene_name": "TRPC7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRNSTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNKGKDI", "length": 862 }, "evidence": [ { "id": "A0A5G2QQ93", "url": "https://omabrowser.org/oma/group/A0A5G2QQ93/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WVC5-1", "protein_name": "Short transient receptor potential channel 7", "gene_name": "Trpc7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGSNTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILSHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNLQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGQTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKASEAQLYVDQYVQDVTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIELCQSKAKRCENDLEMGMLNSKFRKTRYQAGMRNSENLTANSTFSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNQGKDI", "length": 862 }, "evidence": [ { "id": "A0A5G2QQ93", "url": "https://omabrowser.org/oma/group/A0A5G2QQ93/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93" } ], "pmid": "" }, { "name": "inositol 1,4,5 trisphosphate binding", "id": "GO:0070679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070679", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93" } ], "pmid": "" }, { "name": "store-operated calcium channel activity", "id": "GO:0015279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015279", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93" } ], "pmid": "" }, { "name": "cation channel complex", "id": "GO:0034703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034703", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93" } ], "pmid": "" }, { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 657, "end_pos": 659, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 767, "end_pos": 769, "annotation": "n_glycosylation_sequon" }, { "start_pos": 771, "end_pos": 773, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQ93-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 862, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQ93-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ93" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ93" }, { "id": "SM01420", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01420" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transient receptor ion channel", "eco_id": "ECO_0000259", "start_pos": 198, "end_pos": 260, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 339, "end_pos": 341 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 418, "end_pos": 420 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 657, "end_pos": 659 }, { "start_pos": 673, "end_pos": 675 }, { "start_pos": 767, "end_pos": 769 }, { "start_pos": 771, "end_pos": 773 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QS11-1", "uniprot_ac": "A0A5G2QS11", "uniprot_id": "A0A5G2QS11_PIG", "mass": { "chemical_mass": 52443.0, "monoisotopic_mass": 52443.0 }, "refseq": {}, "gene_names": [ { "name": "GORASP1", "type": "recommended", "evidence": [ { "id": "A0A5G2QS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11" } ] } ], "protein_names": [ { "name": "Golgi reassembly stacking protein 1", "type": "synonym", "evidence": [ { "id": "A0A5G2QS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GORASP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11", "locus": { "chromosome": "13", "start_pos": 23786248, "end_pos": 23797487, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034916", "url": "https://www.ensembl.org/id/ENSSSCG00000034916" } ] } } ], "crossref": [ { "id": "A0A5G2QS11", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QS11", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034916", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034916", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100518933", "url": "https://www.ncbi.nlm.nih.gov/gene/100518933", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12893", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12893", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12893:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12893:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04495", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04495", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-162658", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-162658", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AU67", "url": "https://www.uniprot.org/uniprotkb/A0A287AU67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AU67-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AU67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B4K8", "url": "https://www.uniprot.org/uniprotkb/A0A287B4K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B4K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B4K8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QBX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QBX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS11-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLGASAEQPVGGTEGFHLHGVSRPRGAGELGVTGSRLYCGCPGEDGVPFRWEPPARSDPAAFLGPSRSAAAVRSAPAPSANSAGSGSVSWSGQAAPKWHFWRVQENSPAQRAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMKVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPASLAGLCPYTDYVVGSDQILQESEDFFSLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSTPPPGTPPPGTLLPGPNPQDSPAPPGLETGSRQGDYVEALLQAPGSFPEEQLPGPESPDHSTSGLGDFPCSMEIPLQPPPPLQRVMDPGFLDVSGISLLDSSNASVWPNLPSSTELTSTELTSTAVSASGPEDICSSGSSHERGGEATWSGSEFEVSFPDSPGTQAQPDHLPQLTLPDSLTSAASPEDGLSAELLEAQAEEEPASTESPDFGAEAERAASQAQPSTPK", "length": 499, "header": "tr|A0A5G2QS11-1|A0A5G2QS11_PIG Isoform 1 of Golgi reassembly stacking protein 1 OS=Sus scrofa OX=9823 GN=GORASP1 PE=3 SV=1 CANONICAL=A0A5G2QS11-1" }, "isoforms": [ { "isoform_ac": "A0A287AU67-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11/entry#A0A287AU67-1", "sequence": { "sequence": "MGLGASAEQPVGGTEGFHLHGNKENDTLKALLKANVEKPVKLEVFNMKTMKVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPASLAGLCPYTDYVVGSDQILQESEDFFSLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQPPSHHKKPLGVPPPSTPPPGTPPPGTLLPGPNPQDSPAPPGLETGSRQGDYVEALLQAPGSFPEEQLPGPESPDHSTSGLGDFPCSMEIPLQPPPPLQRVMDPGFLDVSGISLLDSSNASVWPNLPSSTELTSTELTSTAVSASGPEDICSSGSSHERGGEATWSGSEFEVSFPDSPGTQAQPDHLPQLTLPDSLTSAASPEDGLSAELLEAQAEEEPASTESPDFGAEAERAASQAQPSTPK", "length": 421, "header": "tr|A0A287AU67-1|A0A5G2QS11_PIG Computationally mapped isoform of Golgi reassembly stacking protein 1 OS=Sus scrofa OX=9823 GN=GORASP1 PE=3 SV=2 CANONICAL=A0A5G2QS11-1" }, "locus": { "chromosome": "13", "start_pos": 23797391, "end_pos": 23788143, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040350.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040350.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047410.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047410.2" } ] } }, { "isoform_ac": "A0A287B4K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11/entry#A0A287B4K8-1", "sequence": { "sequence": "MGLGASAEQPVGGTEGFHLHGVQENSPAQRAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMKVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPASLAGLCPYTDYVVGSDQILQESEDFFSLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSTPPPGTPPPGTLLPGPNPQDSPAPPGLETGSRQGDYVEALLQAPGSFPEEQLPGPESPDHSTSGLGDFPCSMEIPLQPPPPLQRVMDPGFLDVSGISLLDSSNASVWPNLPSSTELTSTELTSTAVSASGPEDICSSGSSHERGGEATWSGSEFEVSFPDSPGTQAQPDHLPQLTLPDSLTSAASPEDGLSAELLEAQAEEEPASTESPDFGAEAERAASQAQPSTPK", "length": 417, "header": "tr|A0A287B4K8-1|A0A287B4K8_PIG Computationally mapped isoform of Golgi reassembly stacking protein 1 OS=Sus scrofa OX=9823 GN=GORASP1 PE=3 SV=2 CANONICAL=A0A5G2QS11-1" }, "locus": { "chromosome": "13", "start_pos": 23797391, "end_pos": 23788143, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044137.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044137.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051366.2", "url": "https://www.ensembl.org/id/ENSSSCP00000051366.2" } ] } }, { "isoform_ac": "A0A5G2QBX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11/entry#A0A5G2QBX7-1", "sequence": { "sequence": "MLQGSGQERAVQENSPAQRAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMKVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPASLAGLCPYTDYVVGSDQILQESEDFFSLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQPPSHHKKPLGVPPPSTPPPGTPPPGTLLPGPNPQDSPAPPGLETGSRQGDYVEALLQAPGSFPEEQLPGPESPDHSTSGLGDFPCSMEIPLQPPPPLQRVMDPGFLDVSGISLLDSSNASVWPNLPSSTELTSTELTSTAVSASGPEDICSSGSSHERGGEATWSGSEFEVSFPDSPGTQAQPDHLPQLTLPDSLTSAASPEDGLSAELLEAQAEEEPASTESPDFGAEAERAASQAQPSTPK", "length": 437, "header": "tr|A0A5G2QBX7-1|A0A5G2QS11_PIG Computationally mapped isoform of Golgi reassembly stacking protein 1 OS=Sus scrofa OX=9823 GN=GORASP1 PE=3 SV=1 CANONICAL=A0A5G2QS11-1" }, "locus": { "chromosome": "13", "start_pos": 23795255, "end_pos": 23788143, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087253.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087253.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061559.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061559.1" } ] } }, { "isoform_ac": "A0A5G2QS11-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11/entry#A0A5G2QS11-1", "sequence": { "sequence": "MGLGASAEQPVGGTEGFHLHGVSRPRGAGELGVTGSRLYCGCPGEDGVPFRWEPPARSDPAAFLGPSRSAAAVRSAPAPSANSAGSGSVSWSGQAAPKWHFWRVQENSPAQRAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMKVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPASLAGLCPYTDYVVGSDQILQESEDFFSLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSTPPPGTPPPGTLLPGPNPQDSPAPPGLETGSRQGDYVEALLQAPGSFPEEQLPGPESPDHSTSGLGDFPCSMEIPLQPPPPLQRVMDPGFLDVSGISLLDSSNASVWPNLPSSTELTSTELTSTAVSASGPEDICSSGSSHERGGEATWSGSEFEVSFPDSPGTQAQPDHLPQLTLPDSLTSAASPEDGLSAELLEAQAEEEPASTESPDFGAEAERAASQAQPSTPK", "length": 499, "header": "tr|A0A5G2QS11-1|A0A5G2QS11_PIG Isoform 1 of Golgi reassembly stacking protein 1 OS=Sus scrofa OX=9823 GN=GORASP1 PE=3 SV=1 CANONICAL=A0A5G2QS11-1" }, "locus": { "chromosome": "13", "start_pos": 23797391, "end_pos": 23788143, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089897.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089897.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067577.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067577.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 277, "start_aa": "Thr", "end_pos": 277, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr277", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QBX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBX7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-162658", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-162658", "resource": "Reactome", "description": "Golgi Cisternae Pericentriolar Stack Reorganization" }, { "id": "R-SSC-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-SSC-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of dendrite morphogenesis", "id": "GO:0050774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050774", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11" } ], "pmid": "" }, { "name": "Golgi ribbon formation", "id": "GO:0090161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090161", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11" } ], "pmid": "" }, { "name": "establishment of protein localization to plasma membrane", "id": "GO:0061951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061951", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QS11-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 499, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QS11-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QS11" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11" }, { "id": "PS51865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ GRASP-type", "eco_id": "ECO_0000259", "start_pos": 97, "end_pos": 187, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A5G2QS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11#function" }, { "id": "A0A5G2QS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11" }, { "id": "PIRSR607583-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607583-1" } ], "binding_site_uniprot": 100, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 100, "end_pos": 100, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287B4K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B4K8#function" }, { "id": "A0A287B4K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B4K8" }, { "id": "PIRSR607583-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607583-1" } ], "binding_site_uniprot": 103, "amino_acid": "Arg", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 103, "end_pos": 103, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287AU67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287AU67#function" }, { "id": "A0A287AU67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287AU67" }, { "id": "PIRSR607583-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607583-1" }, { "id": "A0A287B4K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B4K8#function" }, { "id": "A0A287B4K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B4K8" } ], "binding_site_uniprot": 18, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 18, "end_pos": 18, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11#function" }, { "id": "A0A5G2QS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS11" }, { "id": "PIRSR607583-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607583-1" } ], "binding_site_uniprot": 185, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 185, "end_pos": 185, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287AU67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287AU67#function" }, { "id": "A0A287AU67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287AU67" }, { "id": "PIRSR607583-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607583-1" }, { "id": "A0A287B4K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B4K8#function" }, { "id": "A0A287B4K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287B4K8" } ], "binding_site_uniprot": 20, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 20, "end_pos": 20, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287AU67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287AU67#function" }, { "id": "A0A287AU67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287AU67" }, { "id": "PIRSR607583-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607583-1" } ], "binding_site_uniprot": 76, "amino_acid": "Ala", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 76, "end_pos": 76, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QBX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBX7#function" }, { "id": "A0A5G2QBX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBX7" }, { "id": "PIRSR607583-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607583-1" } ], "binding_site_uniprot": 92, "amino_acid": "Ser", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 92, "end_pos": 92, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 277 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 374, "end_pos": 376 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QW78-1", "uniprot_ac": "A0A5G2QW78", "uniprot_id": "A0A5G2QW78_PIG", "mass": { "chemical_mass": 148120.0, "monoisotopic_mass": 148120.0 }, "refseq": { "ac": "XP_020936068", "name": "protocadherin-11 X-linked isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936068" }, "gene_names": [ { "name": "PCDH11X", "type": "synonym", "evidence": [ { "id": "XP_020936068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936068" } ] } ], "protein_names": [ { "name": "Protocadherin 11 X-linked", "type": "synonym", "evidence": [ { "id": "A0A5G2QW78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78/entry#names_and_taxonomy" } ] }, { "name": "protocadherin-11 X-linked isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020936068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936068" } ] } ], "function": [ { "annotation": "Potential calcium-dependent cell-adhesion protein.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78#function" }, { "database": "UniProtKB", "id": "ARBA00037723", "url": "https://www.uniprot.org/uniprotkb/ARBA00037723#function" }, { "database": "UniProtKB", "id": "A0A287BLB8", "url": "https://www.uniprot.org/uniprotkb/A0A287BLB8#function" }, { "database": "UniProtKB", "id": "A0A5G2R982", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R982#function" }, { "database": "UniProtKB", "id": "I3LUG2", "url": "https://www.uniprot.org/uniprotkb/I3LUG2#function" }, { "database": "UniProtKB", "id": "A0A287BJE2", "url": "https://www.uniprot.org/uniprotkb/A0A287BJE2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000029771", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000029771", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "414736", "url": "https://www.ncbi.nlm.nih.gov/gene/414736", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:414736", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414736", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHTRQVM", "url": "https://omabrowser.org/oma/group/IHTRQVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287BLB8", "url": "https://www.orthodb.org/?gene=A0A287BLB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QW78", "url": "https://www.orthodb.org/?gene=A0A5G2QW78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24026:SF126", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24026:SF126", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08374", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08374", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020936068", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936068", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BJE2", "url": "https://www.uniprot.org/uniprotkb/A0A287BJE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BJE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BJE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLB8", "url": "https://www.uniprot.org/uniprotkb/A0A287BLB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BLB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW78-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R982", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R982", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R982-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R982-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LUG2", "url": "https://www.uniprot.org/uniprotkb/I3LUG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LUG2-1", "url": "https://www.uniprot.org/uniprotkb/I3LUG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLLSGTYIFAVLLACIVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDRSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVVDAHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYHLIKGQSIFGLDVIETPEGEKMPQLIVQKELDREEKDTYVMKIKVEDGGFPQRSSTAILQVSVADTNDNRPVFKENEIEVSIPENAPVGSSVTQLHATDADIGENAKIHFYFSNLISNMAKKLFHLNSTTGLITIKEPLDREESPNHKLLVLASDGGLTPARAMVLVNVTDINDNIPSIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVSCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQPFLSLSVPENNSPGTQLTKISAMDADSGRNAEINYLLGFDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPPLMTNATVLVTVLDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVILSILDANDDFTIDPQTGVIQPNISFDREKQESYTFYVKAEDGGRISRSSTAKVTINVVDVNDNKPVFVVPSSNYSFELVPPSTNPGTVVFTVVAIDNDTGMNAELRYSMVGGNTKGLFIIDQTSGNITLKEKCVFADLGLHRLVVKAKDLGQPDSLFNVVNVNLFVNESVTNATLIYELVRKNIETPVTQNIETTDASSPSSDYVKIVVAIVAGTITVILVIFITAVVRCQQSPHLKAAQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHAPKNLLLNFVTIEEAKADDADNNRSSITLDLPIELEEQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPTFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKTPVSVHTRPPMKEAIRSHTPMKETTTVEIWTHPQPQRKSEGKRAGKSQRRVTFHLPEGSQESSSDGGLGDHDTGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPESAFIPGLKKGAEITVEPTVEEASDNCTQECLILGHSDACWMPASLTHSSPQQTQASGLCHSPPMTQTTLRHRSPPVTQTVALCHSPPVTQTITLCHSPPLAHTSALHHSPPLAKATPLRHSPPPAQASALHYSPTLAQAVAIQHSPPLPQAAALHRSPAQPQMGLQQGWGQGASPDGLNSLNQGLQGSARSQFYTMSERLHPSDDSIKVIPLTTFTPGQQARPSRGESPIMEEHPL", "length": 1350, "header": "tr|A0A5G2QW78-1|A0A5G2QW78_PIG Isoform 1 of Protocadherin 11 X-linked OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QW78-1" }, "isoforms": [ { "isoform_ac": "A0A287BJE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78/entry#A0A287BJE2-1", "sequence": { "sequence": "MDLLSGTYIFAVLLACIVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDRSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVVDAHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYHLIKGQSIFGLDVIETPEGEKMPQLIVQKELDREEKDTYVMKIKVEDGGFPQRSSTAILQVSVADTNDNRPVFKENEIEVSIPENAPVGSSVTQLHATDADIGENAKIHFYFSNLISNMAKKLFHLNSTTGLITIKEPLDREESPNHKLLVLASDGGLTPARAMVLVNVTDINDNIPSIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVSCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQPFLSLSVPENNSPGTQLTKISAMDADSGRNAEINYLLGFDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPPLMTNATVLVTVLDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVILSILDANDDFTIDPQTGVIQPNISFDREKQESYTFYVKAEDGGRISRSSTAKVTINVVDVNDNKPVFVVPSSNYSFELVPPSTNPGTVVFTVVAIDNDTGMNAELRYSMVGGNTKGLFIIDQTSGNITLKEKCVFADLGLHRLVVKAKDLGQPDSLFNVVNVNLFVNESVTNATLIYELVRKNIETPVTQNIETTDASSPSSDYVKIVVAIVAGTITVILVIFITAVVRCQQSPHLKAAQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHAPKNLLLNFVTIEEAKADDADNNRSSITLDLPIELEEQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPTFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKTPVSVHTRPVGNPSF", "length": 1018, "header": "tr|A0A287BJE2-1|A0A287BJE2_PIG Computationally mapped isoform of Protocadherin 11 X-linked OS=Sus scrofa OX=9823 GN= PE=4 SV=3 CANONICAL=A0A5G2QW78-1" }, "locus": { "chromosome": "X", "start_pos": 74541187, "end_pos": 74510342, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053308.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053308.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056727.3", "url": "https://www.ensembl.org/id/ENSSSCP00000056727.3" } ] } }, { "isoform_ac": "A0A287BLB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78/entry#A0A287BLB8-1", "sequence": { "sequence": "MDLLSGTYIFAVLLACIVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDRSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVVDAHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYHLIKGQSIFGLDVIETPEGEKMPQLIVQKELDREEKDTYVMKIKVEDGGFPQRSSTAILQVSVADTNDNRPVFKENEIEVSIPENAPVGSSVTQLHATDADIGENAKIHFYFSNLISNMAKKLFHLNSTTGLITIKEPLDREESPNHKLLVLASDGGLTPARAMVLVNVTDINDNIPSIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVSCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQPFLSLSVPENNSPGTQLTKISAMDADSGRNAEINYLLGFDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPPLMTNATVLVTVLDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVILSILDANDDFTIDPQTGVIQPNISFDREKQESYTFYVKAEDGGRISRSSTAKVTINVVDVNDNKPVFVVPSSNYSFELVPPSTNPGTVVFTVVAIDNDTGMNAELRYSMVGGNTKGLFIIDQTSGNITLKEKCVFADLGLHRLVVKAKDLGQPDSLFNVVNVNLFVNESVTNATLIYELVRKNIETPVTQNIETTDASSPSSDYVKIVVAIVAGTITVILVIFITAVVRCQQSPHLKAAQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHAPKNLLLNFVTIEEAKADDADNNRSSITLDLPIELEEQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPTFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKTPVSVHTRPTDSRTPTIEIYSEI", "length": 1026, "header": "tr|A0A287BLB8-1|A0A287BLB8_PIG Computationally mapped isoform of Protocadherin 11 X-linked OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QW78-1" }, "locus": { "chromosome": "X", "start_pos": 74544631, "end_pos": 74510342, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063417.2", "url": "https://www.ensembl.org/id/ENSSSCT00000063417.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057409.1", "url": "https://www.ensembl.org/id/ENSSSCP00000057409.1" } ] } }, { "isoform_ac": "A0A5G2QW78-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78/entry#A0A5G2QW78-1", "sequence": { "sequence": "MDLLSGTYIFAVLLACIVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDRSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVVDAHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYHLIKGQSIFGLDVIETPEGEKMPQLIVQKELDREEKDTYVMKIKVEDGGFPQRSSTAILQVSVADTNDNRPVFKENEIEVSIPENAPVGSSVTQLHATDADIGENAKIHFYFSNLISNMAKKLFHLNSTTGLITIKEPLDREESPNHKLLVLASDGGLTPARAMVLVNVTDINDNIPSIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVSCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQPFLSLSVPENNSPGTQLTKISAMDADSGRNAEINYLLGFDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPPLMTNATVLVTVLDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVILSILDANDDFTIDPQTGVIQPNISFDREKQESYTFYVKAEDGGRISRSSTAKVTINVVDVNDNKPVFVVPSSNYSFELVPPSTNPGTVVFTVVAIDNDTGMNAELRYSMVGGNTKGLFIIDQTSGNITLKEKCVFADLGLHRLVVKAKDLGQPDSLFNVVNVNLFVNESVTNATLIYELVRKNIETPVTQNIETTDASSPSSDYVKIVVAIVAGTITVILVIFITAVVRCQQSPHLKAAQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHAPKNLLLNFVTIEEAKADDADNNRSSITLDLPIELEEQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPTFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKTPVSVHTRPPMKEAIRSHTPMKETTTVEIWTHPQPQRKSEGKRAGKSQRRVTFHLPEGSQESSSDGGLGDHDTGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPESAFIPGLKKGAEITVEPTVEEASDNCTQECLILGHSDACWMPASLTHSSPQQTQASGLCHSPPMTQTTLRHRSPPVTQTVALCHSPPVTQTITLCHSPPLAHTSALHHSPPLAKATPLRHSPPPAQASALHYSPTLAQAVAIQHSPPLPQAAALHRSPAQPQMGLQQGWGQGASPDGLNSLNQGLQGSARSQFYTMSERLHPSDDSIKVIPLTTFTPGQQARPSRGESPIMEEHPL", "length": 1350, "header": "tr|A0A5G2QW78-1|A0A5G2QW78_PIG Isoform 1 of Protocadherin 11 X-linked OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QW78-1" }, "locus": { "chromosome": "X", "start_pos": 75187732, "end_pos": 74510342, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081395.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081395.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069209.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069209.1" } ] } }, { "isoform_ac": "A0A5G2R982-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78/entry#A0A5G2R982-1", "sequence": { "sequence": "MDLLSGTYIFAVLLACIVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDRSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVVDAHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYHLIKGQSIFGLDVIETPEGEKMPQLIVQKELDREEKDTYVMKIKVEDGGFPQRSSTAILQVSVADTNDNRPVFKENEIEVSIPENAPVGSSVTQLHATDADIGENAKIHFYFSNLISNMAKKLFHLNSTTGLITIKEPLDREESPNHKLLVLASDGGLTPARAMVLVNVTDINDNIPSIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVSCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQPFLSLSVPENNSPGTQLTKISAMDADSGRNAEINYLLGFDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPPLMTNATVLVTVLDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVILSILDANDDFTIDPQTGVIQPNISFDREKQESYTFYVKAEDGGRISRSSTAKVTINVVDVNDNKPVFVVPSSNYSFELVPPSTNPGTVVFTVVAIDNDTGMNAELRYSMVGGNTKGLFIIDQTSGNITLKEKCVFADLGLHRLVVKAKDLGQPDSLFNVVNVNLFVNESVTNATLIYELVRKNIETPVTQNIETTDASSPSSDYVKIVVAIVAGTITVILVIFITAVVRCQQSPHLKAAQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHAPKNLLLNFVTIEEAKADDADNNRSSITLDLPIELEEQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPTFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKTPVSVHTRPPMKEAIRSHTPMKETTTVEIWTHPQPQSQRRVTFHLPEGSQESSSDGGLGDHDTGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPESAFIPGLKKGAEITVEPTVEEASDNCTQECLILGHSDACWMPASLTHSSPQQTQASGLCHSPPMTQTTLRHRSPPVTQTVALCHSPPVTQTITLCHSPPLAHTSALHHSPPLAKATPLRHSPPPAQASALHYSPTLAQAVAIQHSPPLPQAAALHRSPAQPQMGLQQGWGQGASPDGLNSLNQGLQGSARSQFYTMSERLHPSDDSIKVIPLTTFTPGQQARPSRGESPIMEEHPL", "length": 1340, "header": "tr|A0A5G2R982-1|A0A5G2QW78_PIG Computationally mapped isoform of Protocadherin 11 X-linked OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QW78-1" }, "locus": { "chromosome": "X", "start_pos": 75187732, "end_pos": 74510342, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089433.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089433.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070679.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070679.1" } ] } }, { "isoform_ac": "I3LUG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78/entry#I3LUG2-1", "sequence": { "sequence": "MDLLSGTYIFAVLLACIVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDRSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVVDAHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYHLIKGQSIFGLDVIETPEGEKMPQLIVQKELDREEKDTYVMKIKVEDGGFPQRSSTAILQVSVADTNDNRPVFKENEIEVSIPENAPVGSSVTQLHATDADIGENAKIHFYFSNLISNMAKKLFHLNSTTGLITIKEPLDREESPNHKLLVLASDGGLTPARAMVLVNVTDINDNIPSIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVSCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQPFLSLSVPENNSPGTQLTKISAMDADSGRNAEINYLLGFDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPPLMTNATVLVTVLDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVILSILDANDDFTIDPQTGVIQPNISFDREKQESYTFYVKAEDGGRISRSSTAKVTINVVDVNDNKPVFVVPSSNYSFELVPPSTNPGTVVFTVVAIDNDTGMNAELRYSMVGGNTKGLFIIDQTSGNITLKEKCVFADLGLHRLVVKAKDLGQPDSLFNVVNVNLFVNESVTNATLIYELVRKNIETPVTQNIETTDASSPSSDYVKIVVAIVAGTITVILVIFITAVVRCQQSPHLKAAQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHAPKNLLLNFVTIEEAKADDADNNRSSITLDLPIELEEQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPTFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKTPVSVHTRPPMKEAIRSHTPMKETTTVEIWTHPQPQRKSEGKRAGKSQRRVTFHLPEGSQESSSDGGLGDHDTGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPESGAEITVEPTVEEASDNCTQECLILGHSDACWMPASLTHSSPQQTQASGLCHSPPMTQTTLRHRSPPVTQTVALCHSPPVTQTITLCHSPPLAHTSALHHSPPLAKATPLRHSPPPAQASALHYSPTLAQAVAIQHSPPLPQAAALHRSPAQPQMGLQQGWGQGASPDGLNSLNQGLQGSARSQFYTMSERLHPSDDSIKVIPLTTFTPGQQARPSRGESPIMEEHPL", "length": 1342, "header": "tr|I3LUG2-1|A0A5G2QW78_PIG Computationally mapped isoform of Protocadherin 11 X-linked OS=Sus scrofa OX=9823 GN= PE=4 SV=3 CANONICAL=A0A5G2QW78-1" }, "locus": { "chromosome": "X", "start_pos": 75187732, "end_pos": 74510342, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023372.4", "url": "https://www.ensembl.org/id/ENSSSCT00000023372.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027762.3", "url": "https://www.ensembl.org/id/ENSSSCP00000027762.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LUG2", "url": "https://www.uniprot.org/uniprotkb/I3LUG2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:414736", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414736", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LML0-1", "protein_name": "Cadherin domain-containing protein", "gene_name": "LOC538674", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIIVDTHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYQLIKGQNIFGLDIIETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPVFKEDEIEVSIPENAPVGSSVTQLHATDADIGENARIHFYFSSLVSSVAKRLFHLNSTTGLITVKEPLDREESPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPLIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLASDAGKPPLNQSSMLLIKLKDENDNAPVFTQPFISLSVPENNSPGTQLTKISATDADTGRNAEIHYLLGIDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPSLITNATVLVTILDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVTLSILDANDDFTIDPQSGVIQPNISFDREKQESYTFNVKAEDGGRVSHSSTAKVTINVVDVNDNKPVFVVPPSNYSFELVSPSANPGTVVFTVVAIDNDTGMNAELRYSILGGNTKGLFMIDQTTGNITLKEKCVLADLGLHKLIVKAKDLGQPDSLFSVINVNLFVNESMTNATLIYELVRKNIEIPVTQNVETTHTSSPSSDYVKIMVAIVAGTITVILVIFITAVVRCRQSPHLKAAQKNKQNSEWVTPNPENRQMMMMKKKKKHTPKNLLLNFVTIEEAKADDADNDRNTVTLDLPVELEEQTMVKYNWGTTPTTFKPDSPDLAQHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSISECSYPVTNIKTPVSVHTRLPMKEVVRSHTPMKGTTTVEIWTHPQPQQKSKGKRTIKSQRRVTFHLPEGSQESSSDGGLGDHDAGSLSSTSHALPLGYPQEEYFDHAANNNRTEGDGNSDPESK", "length": 1112 }, "evidence": [ { "id": "A0A5G2QW78", "url": "https://omabrowser.org/oma/group/A0A5G2QW78/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0L546-1", "protein_name": "Protocadherin 11 X-linked", "gene_name": "Pcdh11x", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQTPGGSDPCRRASENCAHSRAPRVGGIGLPGMLPFLPALGPSECGNVYRGLTNSTFGIETGMDLLSGTYIFAVLLACVVFQSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKSQNVFGLDVVETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNRPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNNAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTPAKAMVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVTDKDSEHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGRNAEINYLLGFDAPPEFNLDRRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPENLPKHGTVGLITVTDPDYGENSAVTLSVLDVNDQFTIDPQSGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSTAKVTINVVDVNDNKPIFIDPPSNYSFEWVLPSTDPGTVIFKVLAIDNDTGMNAELRYSIVGGNTKGLFMIEQISGNITLKEKCMVSDIGLHRVIVKAKDLGQPDSLFNVVNVNLFVNESVPNTTLIYEMVRKSIDSPANQNSETTSASSPTTDYVKIMVAIVAGTITVVLVIFITAVVRCRQSPHLKASQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHPPKNLLLNFVSIEEAKPDDADNERNSVTLDLPIELEDQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKTPVSVHTRPPMKEVVRSHTPMKEATTVEIWTHPHPQRRSDGKKAGKSQRRVTFHLPEGSQESISDGGLGDHDPGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPESTAEITVQPTVEEASDTCTQECLILGHSDSCWMPASLTNPTPSQIKTSAICHSPPRTHSSVRRCSPPVTQTVAICHSPPVTQAIALCHSPPPVQATVLRHSSPPAQASAVCYSPTLVQAVVIHRSPPLPQAATLRHTQAQPPMGLQQGWVQGAGADGTHPIDQGVQGSTRAQFYTMAERLHPDDDSIKVIPLTTFTSGKQARASRGDSPIMEEHPL", "length": 1393 }, "evidence": [ { "id": "A0A5G2QW78", "url": "https://omabrowser.org/oma/group/A0A5G2QW78/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6ZNL5-1", "protein_name": "Protocadherin 11 X-linked", "gene_name": "Pcdh11x", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAVTLSILDVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSNYSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQPDSLFNVVNVNFFINESVPNATLIYELVRRSIDAPANQNTETTSASSPTTDYVKIMVAIVAGTITVVLVIFITAVVRCRQPPHLKASQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHPPKNLLLNFVTIEEAKPDDGENERNSVTLDLPIELEEQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKAPVSVHIRPTMKEVVRSHTPMKEATTVEIWTHPHPQRRSDGKKAGKSQRRVTFHLPEGSQESISDGGLGDHDAGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDTCTQECLILGHSDSCWMPATLTNPSPSQIKTSAICHSPPRPRLSVRRYSPPVTQTVTICHSPPVTQAIALCHSPPPVQVTVPRHSPPPAQASAVSYSPTLVQAVVIHHSPPLPQAATHHRTQAQPPMGLQQGWVQGAGADGLYPIDQGVQGSTRAQFYTMAERFHPDDDSIKVIPLTTFTSGQQARSSRGDSPIIEEHPL", "length": 1338 }, "evidence": [ { "id": "A0A5G2QW78", "url": "https://omabrowser.org/oma/group/A0A5G2QW78/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZA7-1", "protein_name": "Protocadherin-11 X-linked", "gene_name": "PCDH11X", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPPMKEVVRSCTPMKESTTMEIWIHPQPQRKSEGKVAGKSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDNCTQECLIYGHSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPRVTQTIALCHSPPVTQTIALCHSPPPIQVSALHHSPPLVQATALHHSPPSAQASALCYSPPLAQAAAISHSSPLPQVIALHRSQAQSSVSLQQGWVQGADGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFTPRQQARPSRGDSPIMEEHPL", "length": 1347 }, "evidence": [ { "id": "A0A5G2QW78", "url": "https://omabrowser.org/oma/group/A0A5G2QW78/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1103, "end_pos": 1105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1139, "end_pos": 1141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 703, "end_pos": 705, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" }, { "start_pos": 900, "end_pos": 902, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QW78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW78" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 139, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1103, "end_pos": 1105 }, { "start_pos": 1139, "end_pos": 1141 }, { "start_pos": 145, "end_pos": 147 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 679, "end_pos": 681 }, { "start_pos": 703, "end_pos": 705 }, { "start_pos": 732, "end_pos": 734 }, { "start_pos": 773, "end_pos": 775 }, { "start_pos": 778, "end_pos": 780 }, { "start_pos": 900, "end_pos": 902 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSC0-1", "uniprot_ac": "A0A5G2QSC0", "uniprot_id": "A0A5G2QSC0_PIG", "mass": { "chemical_mass": 16581.0, "monoisotopic_mass": 16581.0 }, "refseq": {}, "gene_names": [ { "name": "CYB5B", "type": "recommended", "evidence": [ { "id": "A0A5G2QSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0" } ] } ], "protein_names": [ { "name": "Cytochrome b5", "type": "recommended", "evidence": [ { "id": "A0A5G2QSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CYB5B", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0", "locus": { "chromosome": "6", "start_pos": 17519289, "end_pos": 17558181, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000033944", "url": "https://www.ensembl.org/id/ENSSSCG00000033944" } ] } } ], "crossref": [ { "id": "A0A5G2QSC0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000033944", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033944", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001199", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001199", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19359:SF95", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19359:SF95", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00173", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00173", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1660661", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660661", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-203615", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-203615", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-211945", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-211945", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SFP8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SFP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SFP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SFP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SGH4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SGH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SGH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SGH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q9T3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q9T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9T3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "IGDPMATVEASGSDGQGVETSVTYYRLEEVAKRNSPKELWLVIHGRVYDVTRFMNEHPGGEEVLMEQAGRDATESFEDVGHSSDAREMLKQYYIGDVHPNDLKSESGKEPPTSGVCKSYWSYWIFPILGAILLGFLYRYYTAAESKSS", "length": 148, "header": "tr|A0A5G2QSC0-1|A0A5G2QSC0_PIG Isoform 1 of Cytochrome b5 OS=Sus scrofa OX=9823 GN=CYB5B PE=1 SV=1 CANONICAL=A0A5G2QSC0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SFP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0/entry#A0A4X1SFP8-1", "sequence": { "sequence": "MATVEASGSDGQGVETSVTYYRLEEVAKRNSPKELWLVIHGRVYDVTRFMNEHPGGEEVLMEQAGRDATESFEDVGHSSDAREMLKQYYIGDVHPNDLKSESGKLLVILDLPHPGRHPLRFSLSLLHGGGEQILLRRLC", "length": 139, "header": "tr|A0A4X1SFP8-1|A0A4X1SFP8_PIG Computationally mapped isoform of Cytochrome b5 OS=Sus scrofa OX=9823 GN=CYB5B PE=1 SV=1 CANONICAL=A0A5G2QSC0-1" }, "locus": { "chromosome": "6", "start_pos": 17557970, "end_pos": 17523000, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057260.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057260.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052993.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052993.2" } ] } }, { "isoform_ac": "A0A4X1SGH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0/entry#A0A4X1SGH4-1", "sequence": { "sequence": "MATVEASGSDGQGVETSVTYYRLEEVAKRNSPKELWLVIHGRVYDVTRFMNEHPGGEEVLMEQAGRDATESFEDVGHSSDAREMLKQYYIGDVHPNDLKSESGKQLRFSPLEFLWWLSGSKPN", "length": 123, "header": "tr|A0A4X1SGH4-1|A0A4X1SGH4_PIG Computationally mapped isoform of Cytochrome b5 OS=Sus scrofa OX=9823 GN=CYB5B PE=1 SV=1 CANONICAL=A0A5G2QSC0-1" }, "locus": { "chromosome": "6", "start_pos": 17557970, "end_pos": 17532299, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003053.3", "url": "https://www.ensembl.org/id/ENSSSCT00000003053.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002974.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002974.3" } ] } }, { "isoform_ac": "A0A5G2Q9T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0/entry#A0A5G2Q9T3-1", "sequence": { "sequence": "IGDPMATVEASGSDGQGVETSVTYYRLEEVAKRNSPKELWLVIHGRVYDVTRFMNEHPGGEEVLMEQAGRDATESFEDVGHSSDAREMLKQYYIGDHPFGLECSRLIASSPPPYPFSYWSYWIFPILGAILLGFLYRYYTAAESKSS", "length": 147, "header": "tr|A0A5G2Q9T3-1|A0A5G2QSC0_PIG Computationally mapped isoform of Cytochrome b5 OS=Sus scrofa OX=9823 GN=CYB5B PE=1 SV=2 CANONICAL=A0A5G2QSC0-1" }, "locus": { "chromosome": "6", "start_pos": 17557982, "end_pos": 17523014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083102.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083102.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060088.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060088.2" } ] } }, { "isoform_ac": "A0A5G2QSC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0/entry#A0A5G2QSC0-1", "sequence": { "sequence": "IGDPMATVEASGSDGQGVETSVTYYRLEEVAKRNSPKELWLVIHGRVYDVTRFMNEHPGGEEVLMEQAGRDATESFEDVGHSSDAREMLKQYYIGDVHPNDLKSESGKEPPTSGVCKSYWSYWIFPILGAILLGFLYRYYTAAESKSS", "length": 148, "header": "tr|A0A5G2QSC0-1|A0A5G2QSC0_PIG Isoform 1 of Cytochrome b5 OS=Sus scrofa OX=9823 GN=CYB5B PE=1 SV=1 CANONICAL=A0A5G2QSC0-1" }, "locus": { "chromosome": "6", "start_pos": 17557982, "end_pos": 17523014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068628.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068628.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067019.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067019.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 141, "start_aa": "Thr", "end_pos": 141, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr141", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2Q9T3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9T3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1660661", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660661", "resource": "Reactome", "description": "Sphingolipid de novo biosynthesis" }, { "id": "R-SSC-203615", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-203615", "resource": "Reactome", "description": "eNOS activation" }, { "id": "R-SSC-211945", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-211945", "resource": "Reactome", "description": "Phase I - Functionalization of compounds" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0" } ], "pmid": "" }, { "name": "nitric-oxide synthase complex", "id": "GO:1903958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903958", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0" } ], "pmid": "" }, { "name": "nitrite reductase (NO-forming) activity", "id": "GO:0050421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050421", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nitric oxide biosynthetic process", "id": "GO:0006809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006809", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSC0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 148, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSC0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSC0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC0" }, { "id": "PS50255", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50255" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytochrome b5 heme-binding", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 98, "start_aa": "Val", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 141 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QT85-1", "uniprot_ac": "A0A5G2QT85", "uniprot_id": "A0A5G2QT85_PIG", "mass": { "chemical_mass": 33115.0, "monoisotopic_mass": 33115.0 }, "refseq": {}, "gene_names": [ { "name": "EXOSC2", "type": "recommended", "evidence": [ { "id": "A0A5G2QT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ] } ], "protein_names": [ { "name": "Exosome complex component RRP4", "type": "recommended", "evidence": [ { "id": "A0A5G2QT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85/entry#names_and_taxonomy" } ] }, { "name": "Exosome component 2", "type": "synonym", "evidence": [ { "id": "A0A5G2QT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85/entry#names_and_taxonomy" } ] }, { "name": "Ribosomal RNA-processing protein 4", "type": "synonym", "evidence": [ { "id": "A0A5G2QT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EXOSC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85", "locus": { "chromosome": "1", "start_pos": 270758111, "end_pos": 270748537, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005704", "url": "https://www.ensembl.org/id/ENSSSCG00000005704" } ] } } ], "crossref": [ { "id": "A0A5G2QT85", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QT85", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005704", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005704", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05789", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05789", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22525", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22525", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21321", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21321", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21321:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21321:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15985", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15985", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-429958", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429958", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-450385", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450385", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-450513", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450513", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-450604", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9930044", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9930044", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TCP8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TCP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TDC9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TDC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QT85-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMEMRLPVARKPLSESLGRETKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYNGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNCIVSLVTQRVMLYDTSILYCYEASLPHQVPHAGLPFSALISEQALSVICSVLPQIAGTQIPLP", "length": 302, "header": "tr|A0A5G2QT85-1|A0A5G2QT85_PIG Isoform 1 of Exosome complex component RRP4 OS=Sus scrofa OX=9823 GN=EXOSC2 PE=1 SV=2 CANONICAL=A0A5G2QT85-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TCP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85/entry#A0A4X1TCP8-1", "sequence": { "sequence": "MAMEMRLPVARKPLSESLGRETKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYNGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNCIVSLVTQRVMLYDTSILYCYEASLPHQIKDILKPEVMEEIVMETRQRLLEQEG", "length": 267, "header": "tr|A0A4X1TCP8-1|A0A4X1TCP8_PIG Computationally mapped isoform of Exosome component 2 OS=Sus scrofa OX=9823 GN=EXOSC2 PE=1 SV=1 CANONICAL=A0A5G2QT85-1" }, "locus": { "chromosome": "1", "start_pos": 270757220, "end_pos": 270748564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079542.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079542.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063138.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063138.1" } ] } }, { "isoform_ac": "A0A4X1TDC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85/entry#A0A4X1TDC9-1", "sequence": { "sequence": "MAMEMRLPVARKPLSESLGRETKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYNGEVGDIVVGRITERRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNCIVSLVTQRVMLYDTSILYCYEASLPHQIKDILKPEVMEEIVMETRQRLLEQEG", "length": 263, "header": "tr|A0A4X1TDC9-1|A0A4X1TDC9_PIG Computationally mapped isoform of Exosome component 2 OS=Sus scrofa OX=9823 GN=EXOSC2 PE=1 SV=1 CANONICAL=A0A5G2QT85-1" }, "locus": { "chromosome": "1", "start_pos": 270757220, "end_pos": 270748564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006273.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006273.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006111.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006111.4" } ] } }, { "isoform_ac": "A0A5G2QT85-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85/entry#A0A5G2QT85-1", "sequence": { "sequence": "MAMEMRLPVARKPLSESLGRETKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYNGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNCIVSLVTQRVMLYDTSILYCYEASLPHQVPHAGLPFSALISEQALSVICSVLPQIAGTQIPLP", "length": 302, "header": "tr|A0A5G2QT85-1|A0A5G2QT85_PIG Isoform 1 of Exosome complex component RRP4 OS=Sus scrofa OX=9823 GN=EXOSC2 PE=1 SV=2 CANONICAL=A0A5G2QT85-1" }, "locus": { "chromosome": "1", "start_pos": 270756753, "end_pos": 270748564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068347.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068347.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068136.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068136.2" } ] } }, { "isoform_ac": "A0A5G2RBC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85/entry#A0A5G2RBC2-1", "sequence": { "sequence": "MAMEMRLPVARKPLSESLGRETKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYNGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNCIVSLVTQRVMLYDTSILYCYEASLPHQIKDILKPEVMEEIVMETRQRLLEQEG", "length": 271, "header": "tr|A0A5G2RBC2-1|A0A5G2QT85_PIG Computationally mapped isoform of Exosome complex component RRP4 OS=Sus scrofa OX=9823 GN=EXOSC2 PE=1 SV=1 CANONICAL=A0A5G2QT85-1" }, "locus": { "chromosome": "1", "start_pos": 270757220, "end_pos": 270748564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068212.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068212.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071461.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071461.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 208, "start_aa": "Thr", "end_pos": 208, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr208", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBC2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-429958", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429958", "resource": "Reactome", "description": "mRNA decay by 3' to 5' exoribonuclease" }, { "id": "R-SSC-450385", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450385", "resource": "Reactome", "description": "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" }, { "id": "R-SSC-450513", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450513", "resource": "Reactome", "description": "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" }, { "id": "R-SSC-450604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450604", "resource": "Reactome", "description": "KSRP (KHSRP) binds and destabilizes mRNA" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-SSC-9930044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9930044", "resource": "Reactome", "description": "Nuclear RNA decay" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "exosome (RNase complex)", "id": "GO:0000178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000178", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000467", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "U4 snRNA 3'-end processing", "id": "GO:0034475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034475", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "CUT catabolic process", "id": "GO:0071034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071034", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" }, { "name": "poly(A)-dependent snoRNA 3'-end processing", "id": "GO:0071051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071051", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QT85-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 302, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QT85-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QT85" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" }, { "id": "PF14382", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exosome complex component N-terminal", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 63, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" }, { "id": "PF15985", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15985" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 169, "end_pos": 209, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT85" }, { "id": "PF21266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRP4 S1", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 146, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 208 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQU7-1", "uniprot_ac": "A0A5G2QQU7", "uniprot_id": "A0A5G2QQU7_PIG", "mass": { "chemical_mass": 109198.0, "monoisotopic_mass": 109198.0 }, "refseq": { "ac": "XP_003131067", "name": "exosome complex exonuclease RRP44 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131067" }, "gene_names": [ { "name": "DIS3", "type": "recommended", "evidence": [ { "id": "A0A5G2QQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ] }, { "name": "DIS3", "type": "synonym", "evidence": [ { "id": "XP_003131067", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131067" } ] } ], "protein_names": [ { "name": "Exosome complex exonuclease RRP44", "type": "recommended", "evidence": [ { "id": "A0A5G2QQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7/entry#names_and_taxonomy" } ] }, { "name": "Protein DIS3 homolog", "type": "synonym", "evidence": [ { "id": "A0A5G2QQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7/entry#names_and_taxonomy" } ] }, { "name": "Ribosomal RNA-processing protein 44", "type": "synonym", "evidence": [ { "id": "A0A5G2QQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7/entry#names_and_taxonomy" } ] }, { "name": "exosome complex exonuclease RRP44 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003131067", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131067" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DIS3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7", "locus": { "chromosome": "11", "start_pos": 45044508, "end_pos": 45075963, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009460", "url": "https://www.ensembl.org/id/ENSSSCG00000009460" } ] } } ], "crossref": [ { "id": "A0A5G2QQU7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQU7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009460", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009460", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09862", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09862", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521470", "url": "https://www.ncbi.nlm.nih.gov/gene/100521470", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022966", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022966", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033771", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033771", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521470", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521470", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GQVMRNN", "url": "https://omabrowser.org/oma/group/GQVMRNN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QQU7", "url": "https://www.orthodb.org/?gene=A0A5G2QQU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23355", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23355", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23355:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23355:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17215", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17215", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17216", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17216", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17849", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17849", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-429958", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429958", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-450385", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450385", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-450513", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450513", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-450604", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9930044", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9930044", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131067", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131067", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1V843", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V843", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V843-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V843-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTB5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1N147", "url": "https://www.uniprot.org/uniprotkb/A0A8D1N147", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1N147-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1N147-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPVLEPQPLDPASSLCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQQQGENSNDRNDRAIRVAAKWYNEHLKKMSAENQLQVIFITNDRKNKEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSDEGNEIESGKVIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWVHGDTEENKEIILQGLKNLNRAVHEDIVAVELLPKNQWVAPSSVVLHDEGQNEDDVEKEEERERILKTAVNEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVSIDGWPRNSRYPNGHFVKNLGEVGDKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCVCSVDPPGCTDIDDALHCRELENGDLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKASLTYAEAQMRIDSAAMNDSITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAAKSKNLEIKTDTAKALADSLDRVDSPIFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGADCTYPELTDKHKLADLCKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPKPRLIYDDEVPSLKIEDTVFHIFDKVKVRIMLDSSNLQHQKIRMLLVEPQIPGISVPTDTSNMDNSEPERKKKKLQK", "length": 958, "header": "tr|A0A5G2QQU7-1|A0A5G2QQU7_PIG Isoform 1 of Exosome complex exonuclease RRP44 OS=Sus scrofa OX=9823 GN=DIS3 PE=1 SV=1 CANONICAL=A0A5G2QQU7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1V843-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7/entry#A0A4X1V843-1", "sequence": { "sequence": "MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPVLEPQPLDPASSLCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQQQGENSNDRNDRAIRVAAKWYNEHLKKMSAENQLQVIFITNDRKNKEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSDEGNEIESGKVIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWVHGDTEENKEIILQGLKNLNRAVHEDIVAVELLPKNQWVAPSSVVLHDEGQNEDDVEKEEERERILKTAVNEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVSIDGWPRNSRYPNGHFVKNLGEVGDKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCVCSVDPPGCTDIDDALHCRELENGDLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKASLTYAEAQMRIDSAAMNDSITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAAKSKNLEIKTDTAKALADSLDRVDSPIFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGADCTYPELTDKHKLADLCKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPKPRLIYDDEIPGISVPTDTSNMDNSEPERKKKKLQK", "length": 917, "header": "tr|A0A4X1V843-1|A0A5G2QQU7_PIG Computationally mapped isoform of Exosome complex exonuclease RRP44 OS=Sus scrofa OX=9823 GN=DIS3 PE=1 SV=1 CANONICAL=A0A5G2QQU7-1" }, "locus": { "chromosome": "11", "start_pos": 45075764, "end_pos": 45048243, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010370.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010370.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010100.3", "url": "https://www.ensembl.org/id/ENSSSCP00000010100.3" } ] } }, { "isoform_ac": "A0A5G2QQU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7/entry#A0A5G2QQU7-1", "sequence": { "sequence": "MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPVLEPQPLDPASSLCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQQQGENSNDRNDRAIRVAAKWYNEHLKKMSAENQLQVIFITNDRKNKEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSDEGNEIESGKVIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWVHGDTEENKEIILQGLKNLNRAVHEDIVAVELLPKNQWVAPSSVVLHDEGQNEDDVEKEEERERILKTAVNEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVSIDGWPRNSRYPNGHFVKNLGEVGDKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCVCSVDPPGCTDIDDALHCRELENGDLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKASLTYAEAQMRIDSAAMNDSITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAAKSKNLEIKTDTAKALADSLDRVDSPIFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGADCTYPELTDKHKLADLCKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPKPRLIYDDEVPSLKIEDTVFHIFDKVKVRIMLDSSNLQHQKIRMLLVEPQIPGISVPTDTSNMDNSEPERKKKKLQK", "length": 958, "header": "tr|A0A5G2QQU7-1|A0A5G2QQU7_PIG Isoform 1 of Exosome complex exonuclease RRP44 OS=Sus scrofa OX=9823 GN=DIS3 PE=1 SV=1 CANONICAL=A0A5G2QQU7-1" }, "locus": { "chromosome": "11", "start_pos": 45075764, "end_pos": 45048243, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086234.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086234.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060654.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060654.1" } ] } }, { "isoform_ac": "A0A5G2QTB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7/entry#A0A5G2QTB5-1", "sequence": { "sequence": "MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPVLEPQPLDPASSLCPQPHYLLPDTNVLLHQILIWRPGTWPSVASSLRPSGSLETYVEQQQGENSNDRNDRAIRVAAKWYNEHLKKMSAENQLQVIFITNDRKNKEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSDEGNEIESGKVIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWVHGDTEENKEIILQGLKNLNRAVHEDIVAVELLPKNQWVAPSSVVLHDEGQNEDDVEKEEERERILKTAVNEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVSIDGWPRNSRYPNGHFVKNLGEVGDKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCVCSVDPPGCTDIDDALHCRELENGDLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKASLTYAEAQMRIDSAAMNDSITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAAKSKNLEIKTDTAKALADSLDRVDSPIFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGADCTYPELTDKHKLADLCKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPKPRLIYDDEVPSLKIEDTVFHIFDKVKVRIMLDSSNLQHQKIRMLLVEPQIPGISVPTDTSNMDNSEPERKKKKLQK", "length": 927, "header": "tr|A0A5G2QTB5-1|A0A5G2QQU7_PIG Computationally mapped isoform of Exosome complex exonuclease RRP44 OS=Sus scrofa OX=9823 GN=DIS3 PE=1 SV=1 CANONICAL=A0A5G2QQU7-1" }, "locus": { "chromosome": "11", "start_pos": 45075764, "end_pos": 45048243, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088088.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088088.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061405.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061405.1" } ] } }, { "isoform_ac": "A0A8D1N147-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7/entry#A0A8D1N147-1", "sequence": { "sequence": "MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPVLEPQPLDPASSLCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQQQGENSNDRNDRAIRVAAKWYNEHLKKMSAENQLQVIFITNDRKNKEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSDEGNEIESGKVIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWVHGDTEENKEIILQGLKNLNRAVHEDIVAVELLPKNQWVAPSSVVLHDEGQNEDDVEKEEERERILKTAVNEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVSIDGWPRNSRYPNGHFVKNLGEVGDKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCVCSVDPPGCTDIDDALHCRELENGDLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAAKSKNLEIKTDTAKALADSLDRVDSPIFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGADCTYPELTDKHKLADLCKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPKPRLIYDDEVPSLKIEDTVFHIFDKVKVRIMLDSSNLQHQKIRMLLVEPQIPGISVPTDTSNMDNSEPERKKKKLQK", "length": 915, "header": "tr|A0A8D1N147-1|A0A5G2QQU7_PIG Computationally mapped isoform of Exosome complex exonuclease RRP44 OS=Sus scrofa OX=9823 GN=DIS3 PE=1 SV=1 CANONICAL=A0A5G2QQU7-1" }, "locus": { "chromosome": "11", "start_pos": 45075764, "end_pos": 45048243, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046267.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046267.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050817.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050817.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V843", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V843" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521470", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521470", "resource": "KEGG Pathway" }, { "id": "R-SSC-429958", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429958", "resource": "Reactome", "description": "mRNA decay by 3' to 5' exoribonuclease" }, { "id": "R-SSC-450385", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450385", "resource": "Reactome", "description": "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" }, { "id": "R-SSC-450513", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450513", "resource": "Reactome", "description": "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" }, { "id": "R-SSC-450604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450604", "resource": "Reactome", "description": "KSRP (KHSRP) binds and destabilizes mRNA" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-SSC-9930044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9930044", "resource": "Reactome", "description": "Nuclear RNA decay" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N1R4-1", "protein_name": "Exosome complex exonuclease RRP44", "gene_name": "DIS3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGASGCAVCDGAHEGPVLELQPLDRASSLCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDMTNNQEKHFYTFTNEHHRETYVEQLQGENSNDRNDRAIRVAAKWYNEHLKNMSAENRLQVIFITNDRKNKEKAIEEGIPAFTCEEYIKSLTANPELIDRLACLSEEGNEIESGKTIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWVHSDDEDNKEILLQGLKNLNRAIHEDIVAVELLPKHQWVAPSSVVLQDEGQNEDDIEKEEERECILKTAVNEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAVDGWPRNSRYPNGHFVKNLGEVGDKETETEVLLLEHDVPHQAFSQAVLSFLPKMPWSITEKDMKNREDLRHLCVCSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMTHNAEILKTRFTKSVINSKASLTYAEAQMRIDSAAMNDNITTSLRGLNKLAKILKKGRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAAKSKNLEIKTDTAKALADSLDQADSPIFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGADCTYPELTDKHKLADLCKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPRLIYDDEIPSLKIEDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISVSADTSNMDINEPERKKKKLQK", "length": 958 }, "evidence": [ { "id": "A0A5G2QQU7", "url": "https://omabrowser.org/oma/group/A0A5G2QQU7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7EPZ4-1", "protein_name": "Exosome complex exonuclease RRP44", "gene_name": "Dis3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSAAARRLARPVARRTRARPWSCSPGTRRAASAHGRTTSCRTPMCCCTRCVDAGPRGDEGAWREGRRVSGWRGKFFGHPRFQLSRPGYLSLTLLHLLVVFGSWSRTFRHVNFLTPGVSSTLDYKCLEAGDLGFCGLQIATPRQLIDVLEDPAIRNVIVLQTVLQEVRNRSAPIYKRIRDVTNNQEKHFYTFTNEHHKETYIEQEQGENANDRNDRAIRVAAKWYNEHLKMSAENQLQVILITNDKKNKEKAAEEGIPAFTCEEYVKSLTANPELIDRLACLSDEMNEIESGKIIFSEHLPLSKLQQGIKSGSYLQGTFRASRENYLEATVWIHGDKEDEKEILIQGLKHLNRAIHEDIVAVELLPKSQWVAPSSVVLHDEGQNEDDVEKDEERELLLKTAVSEKMLRPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASALEGRRIIVAIDGWPRNSRYPNGHFVKNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEEDMKNREDLRHLCVCSVDPPGCTDIDDALHCRELSNGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKASLTYAEAQMRIDSAAMNDDITTSLRGLNKLAKILKRGRIEKGALTLSSPEIRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEVLVKAAKSKNLEIRTDTAKSLADSLDRAECPDFPYLNTLLRILATRCMMQAVYFCSGMDSDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGADCTYPELTDKHKLSDICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPKPRLTYDDEIPSLRIEGTVFHVFDKVKVKITLDSSNLQHQKIRMALVEPQIPGINMPPDVSDMDLNGPGGKKRKLEK", "length": 1026 }, "evidence": [ { "id": "A0A5G2QQU7", "url": "https://omabrowser.org/oma/group/A0A5G2QQU7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08162-1", "protein_name": "Exosome complex exonuclease DIS3", "gene_name": "DIS3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSVPAIAPRRKRLADGLSVTQKVFVRSRNGGATKIVREHYLRSDIPCLSRSCTKCPQIVVPDAQNELPKFILSDSPLELSAPIGKHYVVLDTNVVLQAIDLLENPNCFFDVIVPQIVLDEVRNKSYPVYTRLRTLCRDSDDHKRFIVFHNEFSEHTFVERLPNETINDRNDRAIRKTCQWYSEHLKPYDINVVLVTNDRLNREAATKEVESNIITKSLVQYIELLPNADDIRDSIPQMDSFDKDLERDTFSDFTFPEYYSTARVMGGLKNGVLYQGNIQISEYNFLEGSVSLPRFSKPVLIVGQKNLNRAFNGDQVIVELLPQSEWKAPSSIVLDSEHFDVNDNPDIEAGDDDDNNESSSNTTVISDKQRRLLAKDAMIAQRSKKIQPTAKVVYIQRRSWRQYVGQLAPSSVDPQSSSTQNVFVILMDKCLPKVRIRTRRAAELLDKRIVISIDSWPTTHKYPLGHFVRDLGTIESAQAETEALLLEHDVEYRPFSKKVLECLPAEGHDWKAPTKLDDPEAVSKDPLLTKRKDLRDKLICSIDPPGCVDIDDALHAKKLPNGNWEVGVHIADVTHFVKPGTALDAEGAARGTSVYLVDKRIDMLPMLLGTDLCSLKPYVDRFAFSVIWELDDSANIVNVNFMKSVIRSREAFSYEQAQLRIDDKTQNDELTMGMRALLKLSVKLKQKRLEAGALNLASPEVKVHMDSETSDPNEVEIKKLLATNSLVEEFMLLANISVARKIYDAFPQTAMLRRHAAPPSTNFEILNEMLNTRKNMSISLESSKALADSLDRCVDPEDPYFNTLVRIMSTRCMMAAQYFYSGAYSYPDFRHYGLAVDIYTHFTSPIRRYCDVVAHRQLAGAIGYEPLSLTHRDKNKMDMICRNINRKHRNAQFAGRASIEYYVGQVMRNNESTETGYVIKVFNNGIVVLVPKFGVEGLIRLDNLTEDPNSAAFDEVEYKLTFVPTNSDKPRDVYVFDKVEVQVRSVMDPITSKRKAELLLK", "length": 1001 }, "evidence": [ { "id": "A0A5G2QQU7", "url": "https://omabrowser.org/oma/group/A0A5G2QQU7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54BH9-1", "protein_name": "Ribosomal RNA-processing protein 44", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MQSNKCFYKATKKGTIIKVVNEIYLRDDIPCGHDSCKECKIKLERRTTVEDRALLSNEINTIDSDKILILDTNVILHQIDLLEDPTIKNCIILSTVLDEVKSQNRAIFNRIRDVIKESSRKFYVYSNEYSTFTSITRENGESPNDRNDRAIRVATQWYKSHLHKYSIKVLLITNDKDNLKKAKSLGLDCQTIQDLVFELSDKNPSLVDKLSDPNDDSNEKDNDESKRFQYQEHKPMSMLTEGIKGGKLIQGIFRTSITNYREATVSNREMEKEILIQGIENINRAVDGDIVAVELFDQSKWNTPSTLIMLENEGVEEDDDSIAKDSLISKKQPTGKVVGIIKRNWKPYCGAVEFKQDDNNTTTKTSTGLHFLYFMPIDKRIPKIRIKSRQVSNLIGKRIVVAIDQWDKNSKYPSGHFVKDLGPLGDKETESQVLLLQFDIPHHPFGAAVMKCLPSPDIMDRVTSADMVGRKDLRKECIFSVDPPGCTDIDDALHIKDLGKGIMEVGVHIADVSHFVQEGTAIDEEAANRSTSVYLVDRRIDMLPGELSGNLCSLMSNVDRFAFSCIWKINQHTGEIIAVEYTKSIIRSCASLTYEQAQIRIDDKSQNDQITVNLRNLNSLAKILRKQRFDRGALYLASPQVKFKTEELGGDPSDVEIYQLRETNSMIEEFMLLANIWVAKKIYKHFPGCAMLRRHPTPNKAAFDLLTKLIENKGYKFSTTTSKDLADSLDSAVDKNDSYFNTLCRIMTTRCMSPAKYFSSGSLPYEDFNHYGLATDIYTHFTSPIRRYPDIIVHRLLASAIGIQSVSLNLENKTISALTENNNFRHKMAQYASRGSTQLHTLIFFKGRKSVEDAYIIRVKANAFVVLVPRYGFEGTVYVSDPNSSTATTNGGGGTSNIYNYNHEDQTLGNGIHTFRVFDKVTVEIYVDDSKAHDQKLKINCINPNISFVPSDDIDSNNLDDILNQENNINKSTSSTSSSNKSSKVRKQPENIKSSTKPTSNKKLKK", "length": 1006 }, "evidence": [ { "id": "A0A5G2QQU7", "url": "https://omabrowser.org/oma/group/A0A5G2QQU7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9CSH3-1", "protein_name": "Exosome complex exonuclease RRP44", "gene_name": "Dis3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRSKTFLKKTRAGGVVKIVREHYLRDDIGCGAPACSACGGAHAGPALELQPRDQASSLCPWPHYLLPDTNVLLHQIDVLEHPAIRNVIVLQTVMQEVRNRSAPIYKRIRDVTNNQEKHFYTFTNEHHKETYIEQEQGENANDRNDRAIRVAAKWYNEHLKRVAADSQLQVILITNDRKNKEKAVQEGIPAFTCEEYVKSLTANPELIDRLAYLSDEMNEIESGKIIFSEHLPLSKLQQGIKSGSYLQGTFRASRENYLEATVWIHGDKEEEKEILIQGIKHLNRAVHEDIVAVELLPRSQWVAPSSVVLDDEGQNEDDVEKDEERELLLKTAVSEKMLRPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASALEGRRIIVAIDGWPRNSRYPNGHFVKNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPRMPWSITEEDMKNREDLRHLCVCSVDPPGCTDIDDALHCRELSNGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKASLTYAEAQMRIDSAAMNDDITTSLRGLNQLAKILKKGRIEKGALTLSSPEIRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYDILVKAAKSKNLQIKTDTAKSLADSLDRAESPDFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGADCTYPELTDKHKLSDICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPKPRLAYDDEIPSLRIEGTVFHVFDKVKVKITLDSSNLQHQKIRMALVEPQIPGINIPPNVADKALTAPGGKKRKLEK", "length": 958 }, "evidence": [ { "id": "A0A5G2QQU7", "url": "https://omabrowser.org/oma/group/A0A5G2QQU7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SHL7-1", "protein_name": "Exosome complex exonuclease RRP44 homolog A", "gene_name": "RRP44A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MLQSKVFNKKTRGGRIQKQVREVYLRDDIYCGAFSCKSCDSSAARLSSSKIIVVDTNVVLHQIDLLENKAIDTVVVLSVVLDEVKNRNRSVYNRIRLLCSNPARQFYVFSNHVHKDTYVQAMEKESANDHNDRAIRVATLWYQKHLGDTSQVLLVTNDRENKRKATEEGISAETIEAYVKSLGQPELLDLLAQPTNEDITMEDADDSRPSKRKLIYQEHKPMSEITAGLHRGIYHQGKLRVNRFNPYEAYVGSESIGEEIIIYGRSNMNRAFDGDIVAVELLPRDQWQDEKALSIAEEDDEEDDTVHLAPDNVDDAPRTSNLSHETSGDKNAAPVRPSGRVVGVIRRNWHSYCGSLEPMSLPAGSGGTAHALFVSKDRRIPKIRINTRQLQNLLDMRIVVAVDSWDRQSRYPSGHYVRPIGKIGDKETETEVVLIENDVDYSPFSSQVLACLPPLPWSVSSEDVSNPVRQDLRHLLVFSVDPPGCKDIDDALHCTSLPNGNFELGVHIADVTNFVHPGTPLDDEASKRGTSVYLVERRIDMLPKPLTEDICSLRADVERLAFSVIWEMSPDAEIISTRFTKSIIKSSAALSYIEAQARMDDSRLTDSLTTDLRNMNTLAKIMRQRRIDRGALTLASAEVKFDIDPENHDPLNIGMYQILEANQMVEEFMLAANVSVAGQILKLFPSCSLLRRHPTPTREMLEPLLRTAAAIGLTLDVSSSKALADSLDRAVGEDPYFNKLIRILATRCMTQAVYFCSGDLSPPEYHHYGLAAPLYTHFTSPIRRYADVFVHRLLAASLGIYKLPTVFQDRPQLTSVADNLNYRHRNAQMAGRASVELYVLIYFRTRPTDEEARVVKIRSNGFIVFVPKYGIEGPVYLTGKGEKGAGDWYVDEEKQKIVKMDGSLSYSVLQTVKIHMEVVEPQPNRPKLQLTLL", "length": 933 }, "evidence": [ { "id": "A0A5G2QQU7", "url": "https://omabrowser.org/oma/group/A0A5G2QQU7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VC93-1", "protein_name": "Exosome complex exonuclease RRP44", "gene_name": "Dis3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQTLREFTRKTKRGNILKIVREHYLRDDIGCGSELCRECFQNEVYQLTSQHANKSTLFKFPHYLVLDTNVVLDQIDVLEEDVLRNVVVLTTVLNEVKHRSSAIYKRFNEIVHDRTRNFYVFVNEHHKETYADREPDETANDRNDRAIRLATKWYDDHLQASQSSKEFERSGKAATRVVLLTDDAANRAKAEAEGILVTTAAEYVKSLEDFPLLMDKLSHKTFDSEKNGLPQYPPHLSMKELLEGLRQNKLLQGTFQASRENYLEGTVNVEKFEKGILIQGRESLNRAVDGDLVAVELLPEAEWSAPSEIVLEEKNVYADEVPSEERAKDENEMLNQVRAAALSAERTPTGRIVGIVRRKWRQYCGILQPSLIEDTNRHIFVPADRKIPRIRIETRQAAMLQNQRIIVTIDTWPRNSRYPHGHFVRSLGPLGDMATENEVILLEHDVPHCKFSDEVLSFLPKMPWTITDEDYSKRVDLRDLYICSVDPPGCTDIDDALHCKELPNGNLEVGVHIADVSHFIRPGNALDMEAAARGTTVYLVGKRIDMVPELLSSNLCSLVGGVERFAFSCVWEVDNEANVLSKRFHKSVIKSKRAMTYEEAQNIIDDATQQNEIAKSLRNLNRLAKILKKRRMDNGALVLASPEIRFQVDSETHEPLEVEVKQMRETNSMVEEFMLLANITVAEHIATEFSECAVLRRHPRPPPTNFDPLVKSARYQGFQVDINSGLELSHSLDKCVKADNPYFNTMIRILTTRCMMQAVYFISGSLQKEEFFHYGLAAPIYTHFTSPIRRYSDIMVHRLLAASIGADSTYAQLLDRKSNEELCHNLNYRHKMAQYAGRASVALNTHLFFRGKEEDEEGYVLFVRKNALQVLIPKYGLEGTLYLKSDKDGKDGVERVKSEIVFTFNEEDHTQRCGDVVFHSFDPVTVRLSLDSSNVQHEKLIFRLVKPYIKGFSVETTTEGTDSQAVSAAPPSKKTKKDKKKK", "length": 982 }, "evidence": [ { "id": "A0A5G2QQU7", "url": "https://omabrowser.org/oma/group/A0A5G2QQU7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y2L1-1", "protein_name": "Exosome complex exonuclease RRP44", "gene_name": "DIS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSANMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK", "length": 958 }, "evidence": [ { "id": "A0A5G2QQU7", "url": "https://omabrowser.org/oma/group/A0A5G2QQU7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" }, { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" }, { "name": "CUT catabolic process", "id": "GO:0071034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071034", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" }, { "name": "nuclear mRNA surveillance of mRNA 3'-end processing", "id": "GO:0071031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071031", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 671, "end_pos": 673, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQU7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 958, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQU7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQU7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" }, { "id": "SM00670", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00670" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIN", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 182, "start_aa": "His", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQU7" }, { "id": "SM00955", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00955" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNB", "eco_id": "ECO_0000259", "start_pos": 467, "end_pos": 797, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 603, "end_pos": 605 }, { "start_pos": 671, "end_pos": 673 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QW28-1", "uniprot_ac": "A0A5G2QW28", "uniprot_id": "A0A5G2QW28_PIG", "mass": { "chemical_mass": 194574.0, "monoisotopic_mass": 194574.0 }, "refseq": {}, "gene_names": [ { "name": "TRPM3", "type": "recommended", "evidence": [ { "id": "A0A5G2QW28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28" } ] } ], "protein_names": [ { "name": "Transient receptor potential cation channel subfamily M member 3", "type": "recommended", "evidence": [ { "id": "A0A5G2QW28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW28", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TRPM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28", "locus": { "chromosome": "1", "start_pos": 223836213, "end_pos": 224680389, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005257", "url": "https://www.ensembl.org/id/ENSSSCG00000005257" } ] } } ], "crossref": [ { "id": "ENSSSCG00000005257", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005257", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13800", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13800", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13800:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13800:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16519", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16519", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18139", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18139", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25508", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25508", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "28699", "url": "https://www.rhea-db.org/rhea/28699", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29351", "url": "https://www.rhea-db.org/rhea/29351", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29827", "url": "https://www.rhea-db.org/rhea/29827", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1VYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VYG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VYG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VYG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QM35", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QM35-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS60", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS60-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW28", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW28-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJC7", "url": "https://www.uniprot.org/uniprotkb/F1SJC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJC7-1", "url": "https://www.uniprot.org/uniprotkb/F1SJC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGPWGTVCFLGTAQVCDFWFSRWNLEGVMNQTDAPRPLNWTIRKLCHAAFLPSVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNDKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDVPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEQEEPEKPTKEKDEEDMELTAMLGRNNGESSRKKDEEEVQSRHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHCMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETLSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESLFKERSLSLHRATSSHSVAKESKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSMNILGLGEPSFSAPVPSTAPSSSAYATLVPTDRPPSRSIDCEDITTMDTRSFSSDYTHLPECQNPWDTDPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYTNFGVPMKTAEYTSITDCIDTRCVTAPQVTADRATFPGGLGGKVEDSSCCHPEREAELSHPSSDSEENEAKGRRATIAIPSQEGDNSDRTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSRSSKPEGRGDSLSMRRLSRTSAFRSFESKHN", "length": 1706, "header": "tr|A0A5G2QW28-1|A0A5G2QW28_PIG Isoform 1 of Transient receptor potential cation channel subfamily M member 3 OS=Sus scrofa OX=9823 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A5G2QW28-1" }, "isoforms": [ { "isoform_ac": "A0A4X1VYG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28/entry#A0A4X1VYG4-1", "sequence": { "sequence": "MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLDSRLFYSFWGSCQLDPIGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGSKGTNNLKRERKEDEKSNSI", "length": 275, "header": "tr|A0A4X1VYG4-1|A0A5G2QW28_PIG Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 3 OS=Sus scrofa OX=9823 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A5G2QW28-1" }, "locus": { "chromosome": "1", "start_pos": 224119346, "end_pos": 224033762, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043786.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043786.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037298.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037298.2" } ] } }, { "isoform_ac": "A0A5G2QFP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28/entry#A0A5G2QFP1-1", "sequence": { "sequence": "MPGPWGTVCFLGTAQVCDFWFSRWNLEGVMNQTDAPRPLNWTIRKLCHAAFLPSVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNDKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDVPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEQEEPEKPTKEKDEEDMELTAMLGRNNGESSRKKDEEEVQSRHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHCMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAEHPFYSV", "length": 1324, "header": "tr|A0A5G2QFP1-1|A0A5G2QW28_PIG Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 3 OS=Sus scrofa OX=9823 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A5G2QW28-1" }, "locus": { "chromosome": "1", "start_pos": 224373550, "end_pos": 223839689, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075867.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075867.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062575.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062575.1" } ] } }, { "isoform_ac": "A0A5G2QM35-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28/entry#A0A5G2QM35-1", "sequence": { "sequence": "MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVSPGSCPCM", "length": 123, "header": "tr|A0A5G2QM35-1|A0A5G2QW28_PIG Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 3 OS=Sus scrofa OX=9823 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A5G2QW28-1" }, "locus": { "chromosome": "1", "start_pos": 224119346, "end_pos": 224099688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085980.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085980.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065937.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065937.1" } ] } }, { "isoform_ac": "A0A5G2QS60-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28/entry#A0A5G2QS60-1", "sequence": { "sequence": "MGKKWRDAAEMERGCSDREDSAESRRRSRSASRGRFAESWKRLSSKQGSTKRSGLPSQQTPAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNDKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDVPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEQEEPEKPTKEKDEEDMELTAMLGRNNGESSRKKDEEEVQSRHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHCMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETLSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESLFKERSLSLHRATSSHSVAKESKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSMNILGLGEPSFSAPVPSTAPSSSAYATLVPTDRPPSRSIDCEDITTMDTRSFSSDYTHLPECQNPWDTDPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYTNFGVPMKTAEYTSITDCIDTRCVTAPQVTADRATFPGGLGGKVEDSSCCHPEREAELSHPSSDSEENEAKGRRATIAIPSQEGDNSDRTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSRSSKPEGRGDSLSMRRLSRTSAFRSFESKHN", "length": 1710, "header": "tr|A0A5G2QS60-1|A0A5G2QS60_PIG Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 3 OS=Sus scrofa OX=9823 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A5G2QW28-1" }, "locus": { "chromosome": "1", "start_pos": 224680190, "end_pos": 223840203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087969.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087969.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064842.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064842.1" } ] } }, { "isoform_ac": "A0A5G2QW28-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28/entry#A0A5G2QW28-1", "sequence": { "sequence": "MPGPWGTVCFLGTAQVCDFWFSRWNLEGVMNQTDAPRPLNWTIRKLCHAAFLPSVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNDKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDVPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEQEEPEKPTKEKDEEDMELTAMLGRNNGESSRKKDEEEVQSRHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHCMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETLSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESLFKERSLSLHRATSSHSVAKESKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSMNILGLGEPSFSAPVPSTAPSSSAYATLVPTDRPPSRSIDCEDITTMDTRSFSSDYTHLPECQNPWDTDPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYTNFGVPMKTAEYTSITDCIDTRCVTAPQVTADRATFPGGLGGKVEDSSCCHPEREAELSHPSSDSEENEAKGRRATIAIPSQEGDNSDRTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSRSSKPEGRGDSLSMRRLSRTSAFRSFESKHN", "length": 1706, "header": "tr|A0A5G2QW28-1|A0A5G2QW28_PIG Isoform 1 of Transient receptor potential cation channel subfamily M member 3 OS=Sus scrofa OX=9823 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A5G2QW28-1" }, "locus": { "chromosome": "1", "start_pos": 224373550, "end_pos": 223840203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066964.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066964.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068355.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068355.1" } ] } }, { "isoform_ac": "F1SJC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28/entry#F1SJC7-1", "sequence": { "sequence": "MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLDSRLFYSFWGSCQLDPIGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDVPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEQEEPEKPTKEKDEEDMELTAMLGRNNGESSRKKDEEEVQSRHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHCMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETLSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESLFKERSLSLHRATSSHSVAKESKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSMNILGLGEPSFSAPVPSTAPSSSAYATLVPTDRPPSRSIDCEDITTMDTRSFSSDYTHLPECQNPWDTDPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYTNFGVPMKTAEYTSITDCIDTRCVTAPQVTADRATFPGGLGGKVEDSSCCHPEREAELSHPSSDSEENEAKGRRATIAIPSQEGDNSDRTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSRSSKPEGRGDSLSMRRLSRTSAFRSFESKHN", "length": 1578, "header": "tr|F1SJC7-1|F1SJC7_PIG Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 3 OS=Sus scrofa OX=9823 GN=TRPM3 PE=3 SV=4 CANONICAL=A0A5G2QW28-1" }, "locus": { "chromosome": "1", "start_pos": 224119346, "end_pos": 223840203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005792.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005792.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005649.4", "url": "https://www.ensembl.org/id/ENSSSCP00000005649.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VYG4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "monoatomic cation transmembrane transport", "id": "GO:0098655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098655", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW28", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28" } ], "pmid": "" }, { "name": "protein tetramerization", "id": "GO:0051262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051262", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW28", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW28", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW28", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW28", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW28", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1067, "end_pos": 1069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1112, "end_pos": 1114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1210, "end_pos": 1212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1226, "end_pos": 1228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1625, "end_pos": 1627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" }, { "start_pos": 731, "end_pos": 733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 941, "end_pos": 943, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "28699", "name": "", "equation": "Mn(2+)(in) = Mn(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "28699", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/28699" } ] }, { "id": "29351", "name": "", "equation": "Zn(2+)(in) = Zn(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29351", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29351" } ] }, { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] }, { "id": "29827", "name": "", "equation": "Mg(2+)(in) = Mg(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29827", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29827" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QW28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 879, "end_pos": 1120, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QW28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28" }, { "id": "PF18139", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18139" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRPM SLOG", "eco_id": "ECO_0000259", "start_pos": 153, "end_pos": 417, "start_aa": "Ala", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QW28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28" }, { "id": "PF16519", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16519" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRPM tetramerisation", "eco_id": "ECO_0000259", "start_pos": 1214, "end_pos": 1269, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QW28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW28" }, { "id": "PF25508", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25508" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRPM-like", "eco_id": "ECO_0000259", "start_pos": 472, "end_pos": 749, "start_aa": "Gln", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1067, "end_pos": 1069 }, { "start_pos": 1112, "end_pos": 1114 }, { "start_pos": 111, "end_pos": 113 }, { "start_pos": 1210, "end_pos": 1212 }, { "start_pos": 1226, "end_pos": 1228 }, { "start_pos": 1625, "end_pos": 1627 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 728, "end_pos": 730 }, { "start_pos": 731, "end_pos": 733 }, { "start_pos": 941, "end_pos": 943 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQH0-1", "uniprot_ac": "A0A5G2QQH0", "uniprot_id": "A0A5G2QQH0_PIG", "mass": { "chemical_mass": 28285.0, "monoisotopic_mass": 28285.0 }, "refseq": {}, "gene_names": [ { "name": "TMBIM4", "type": "recommended", "evidence": [ { "id": "A0A5G2QQH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0" } ] } ], "protein_names": [ { "name": "Transmembrane BAX inhibitor motif containing 4", "type": "synonym", "evidence": [ { "id": "A0A5G2QQH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMBIM4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0", "locus": { "chromosome": "5", "start_pos": 30488328, "end_pos": 30511533, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000473", "url": "https://www.ensembl.org/id/ENSSSCG00000000473" } ] } } ], "crossref": [ { "id": "A0A5G2QQH0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQH0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000473", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000473", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10429", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10429", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23291", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23291", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23291:SF50", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23291:SF50", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1W5A2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W5A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1W5A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W5A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSTMAAAWPPPACTSEWSHLFRTKDTPATQKTTRVLGTLCQGNWAAFLRKVYSILSLQVLLTTMTSTFFLYFDSVRAFVHESPALILVFALGSLGLILALTLNRHKHPLNLYLLFGFTLLEALTVAFVVTFYDVYIVLQAFILTTAVFLGLTVYTLQSKRDFSKFGAGLFAVLWILCLSGILKVFFYSETMELVLAAVGALLFCGFIIYDTHSLMHRLSPEEYVLAAISLYLDIINLFLHLLRVLEAVNKK", "length": 252, "header": "tr|A0A5G2QQH0-1|A0A5G2QQH0_PIG Isoform 1 of Transmembrane BAX inhibitor motif containing 4 OS=Sus scrofa OX=9823 GN=TMBIM4 PE=3 SV=2 CANONICAL=A0A5G2QQH0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1W5A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0/entry#A0A4X1W5A2-1", "sequence": { "sequence": "MADPDPRYPCSSIEDDFNYGSCVASASVHIRMAFLRKVYSILSLQVLLTTMTSTFFLYFDSVRAFVHESPALILVFALGSLGLILALTLNRHKHPLNLYLLFGFTLLEALTVAFVVTFYDVYIVLQAFILTTAVFLGLTVYTLQSKRDFSKFGAGIV", "length": 157, "header": "tr|A0A4X1W5A2-1|A0A5G2QQH0_PIG Computationally mapped isoform of Transmembrane BAX inhibitor motif containing 4 OS=Sus scrofa OX=9823 GN=TMBIM4 PE=3 SV=1 CANONICAL=A0A5G2QQH0-1" }, "locus": { "chromosome": "5", "start_pos": 30511465, "end_pos": 30493986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090819.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090819.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069356.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069356.1" } ] } }, { "isoform_ac": "A0A5G2QLT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0/entry#A0A5G2QLT1-1", "sequence": { "sequence": "MADPDPRYPCSSIEDDFNYGSCVASASVHIRMAFLRKVYSILSLQVLLTTMTSTFFLYFDSVRAFVHESPALILVFALGSLGLILALTLNRHKHPLNLYLLFGFTLLEALTVAFVVTFYDVYIVLQAFILTTAVFLGLTVYTLQSKRDFSKFGAGYFFTVRQWSWSWLP", "length": 169, "header": "tr|A0A5G2QLT1-1|A0A5G2QQH0_PIG Computationally mapped isoform of Transmembrane BAX inhibitor motif containing 4 OS=Sus scrofa OX=9823 GN=TMBIM4 PE=3 SV=1 CANONICAL=A0A5G2QQH0-1" }, "locus": { "chromosome": "5", "start_pos": 30511465, "end_pos": 30490755, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071982.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071982.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063040.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063040.1" } ] } }, { "isoform_ac": "A0A5G2QQH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0/entry#A0A5G2QQH0-1", "sequence": { "sequence": "MTSTMAAAWPPPACTSEWSHLFRTKDTPATQKTTRVLGTLCQGNWAAFLRKVYSILSLQVLLTTMTSTFFLYFDSVRAFVHESPALILVFALGSLGLILALTLNRHKHPLNLYLLFGFTLLEALTVAFVVTFYDVYIVLQAFILTTAVFLGLTVYTLQSKRDFSKFGAGLFAVLWILCLSGILKVFFYSETMELVLAAVGALLFCGFIIYDTHSLMHRLSPEEYVLAAISLYLDIINLFLHLLRVLEAVNKK", "length": 252, "header": "tr|A0A5G2QQH0-1|A0A5G2QQH0_PIG Isoform 1 of Transmembrane BAX inhibitor motif containing 4 OS=Sus scrofa OX=9823 GN=TMBIM4 PE=3 SV=2 CANONICAL=A0A5G2QQH0-1" }, "locus": { "chromosome": "5", "start_pos": 30511422, "end_pos": 30490594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072532.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072532.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066977.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066977.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1W5A2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W5A2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0" } ], "pmid": "" }, { "name": "regulation of calcium-mediated signaling", "id": "GO:0050848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050848", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQH0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 252, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQH0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQH0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRM0-1", "uniprot_ac": "A0A5G2QRM0", "uniprot_id": "A0A5G2QRM0_PIG", "mass": { "chemical_mass": 30487.0, "monoisotopic_mass": 30487.0 }, "refseq": { "ac": "NP_001231284", "name": "tumor protein p63-regulated gene 1-like protein isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231284" }, "gene_names": [ { "name": "TPRG1L", "type": "recommended", "evidence": [ { "id": "A0A5G2QRM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0" } ] }, { "name": "TPRG1L", "type": "synonym", "evidence": [ { "id": "NP_001231284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231284" } ] } ], "protein_names": [ { "name": "Tumor protein p63 regulated 1 like", "type": "synonym", "evidence": [ { "id": "A0A5G2QRM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0/entry#names_and_taxonomy" } ] }, { "name": "tumor protein p63-regulated gene 1-like protein isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001231284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231284" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRM0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TPRG1L", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0", "locus": { "chromosome": "6", "start_pos": 65154429, "end_pos": 65150903, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003359", "url": "https://www.ensembl.org/id/ENSSSCG00000003359" } ] } } ], "crossref": [ { "id": "A0A5G2QRM0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003359", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003359", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100512473", "url": "https://www.ncbi.nlm.nih.gov/gene/100512473", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512473", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512473", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNPWSSN", "url": "https://omabrowser.org/oma/group/WNPWSSN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QRM0", "url": "https://www.orthodb.org/?gene=A0A5G2QRM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1RJA8", "url": "https://www.orthodb.org/?gene=F1RJA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31108:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31108:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231284", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231284", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QAR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QAR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRM0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ59", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ59-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RJA8", "url": "https://www.uniprot.org/uniprotkb/F1RJA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RJA8-1", "url": "https://www.uniprot.org/uniprotkb/F1RJA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQLRDSVDSAGTSPTALLAAGEEVGPGGGGSGGGGGGGRPGVGTPLRQTLWPLSIHDPTRRARVKEYFVFRPGTIEQAVEEIRVVVRPVEDGDIQGVWLLTEVDHWNNEKERLVLITDQSLLICKYDFISLQCQQVVRVALSAVDTISYGEFQFPPKSLNKREGVGVRIQWDKQSRPSFISRWNPWSTSVPYTTFTEHPMAGVDEKTASLCQLEDFKALLIQAVKKAQKESPWPGQAGGVLVLERPLLIETYVGLMSFISNEAKLGYSMTRGRIGF", "length": 277, "header": "tr|A0A5G2QRM0-1|A0A5G2QRM0_PIG Isoform 1 of Tumor protein p63 regulated 1 like OS=Sus scrofa OX=9823 GN=TPRG1L PE=3 SV=1 CANONICAL=A0A5G2QRM0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QAR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0/entry#A0A5G2QAR1-1", "sequence": { "sequence": "MLQLRDSVDSAGTSPTALLAAGEEVGPGGGGSGGGGGGGRPGVGTPLRQTLWPLSIHDPTRRARVKEYFVFRPGTIEQAVEEIRVVVRPVEDGDIQGVWLLTEREGVGVRIQWDKQSRPSFISRWNPWSTSVPYTTFTEHPMAGVDEKTASLCQLEDFKALLIQAVKKAQKESPWPGQAGGVLVLERPLLIETYVGLMSFISNEAKLGYSMTRGRIGF", "length": 218, "header": "tr|A0A5G2QAR1-1|A0A5G2QRM0_PIG Computationally mapped isoform of Tumor protein p63 regulated 1 like OS=Sus scrofa OX=9823 GN=TPRG1L PE=3 SV=1 CANONICAL=A0A5G2QRM0-1" }, "locus": { "chromosome": "6", "start_pos": 65153754, "end_pos": 65150976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072622.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072622.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061497.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061497.1" } ] } }, { "isoform_ac": "A0A5G2QRM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0/entry#A0A5G2QRM0-1", "sequence": { "sequence": "MLQLRDSVDSAGTSPTALLAAGEEVGPGGGGSGGGGGGGRPGVGTPLRQTLWPLSIHDPTRRARVKEYFVFRPGTIEQAVEEIRVVVRPVEDGDIQGVWLLTEVDHWNNEKERLVLITDQSLLICKYDFISLQCQQVVRVALSAVDTISYGEFQFPPKSLNKREGVGVRIQWDKQSRPSFISRWNPWSTSVPYTTFTEHPMAGVDEKTASLCQLEDFKALLIQAVKKAQKESPWPGQAGGVLVLERPLLIETYVGLMSFISNEAKLGYSMTRGRIGF", "length": 277, "header": "tr|A0A5G2QRM0-1|A0A5G2QRM0_PIG Isoform 1 of Tumor protein p63 regulated 1 like OS=Sus scrofa OX=9823 GN=TPRG1L PE=3 SV=1 CANONICAL=A0A5G2QRM0-1" }, "locus": { "chromosome": "6", "start_pos": 65153754, "end_pos": 65150976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071764.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071764.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066717.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066717.1" } ] } }, { "isoform_ac": "A0A5G2QZ59-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0/entry#A0A5G2QZ59-1", "sequence": { "sequence": "MLQLRDSVDSAGTSPTALLAAGEETLWPLSIHDPTRRARVKEYFVFRPGTIEQAVEEIRVVVRPVEDGDIQGVWLLTEVDHWNNEKERLVLITDQSLLICKYDFISLQCQQVVRVALSAVDTISYGEFQFPPKSLNKREGVGVRIQWDKQSRPSFISRWNPWSTSVPYTTFTEHPMAGVDEKTASLCQLEDFKALLIQAVKKAQKESPWPGQAGGVLVLERPLLIETYVGLMSFISNEAKLGYSMTRGRIGF", "length": 252, "header": "tr|A0A5G2QZ59-1|A0A5G2QRM0_PIG Computationally mapped isoform of Tumor protein p63 regulated 1 like OS=Sus scrofa OX=9823 GN=TPRG1L PE=3 SV=1 CANONICAL=A0A5G2QRM0-1" }, "locus": { "chromosome": "6", "start_pos": 65153754, "end_pos": 65150976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075531.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075531.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070181.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070181.1" } ] } }, { "isoform_ac": "F1RJA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0/entry#F1RJA8-1", "sequence": { "sequence": "MLQLRDSVDSAGTSPTALLAAGEEPGTIEQAVEEIRVVVRPVEDGDIQGVWLLTEVDHWNNEKERLVLITDQSLLICKYDFISLQCQQVVRVALSAVDTISYGEFQFPPKSLNKREGVGVRIQWDKQSRPSFISRWNPWSTSVPYTTFTEHPMAGVDEKTASLCQLEDFKALLIQAVKKAQKESPWPGQAGGVLVLERPLLIETYVGLMSFISNEAKLGYSMTRGRIGF", "length": 229, "header": "tr|F1RJA8-1|A0A5G2QRM0_PIG Computationally mapped isoform of Tumor protein p63 regulated 1 like OS=Sus scrofa OX=9823 GN=TPRG1L PE=3 SV=2 CANONICAL=A0A5G2QRM0-1" }, "locus": { "chromosome": "6", "start_pos": 65153754, "end_pos": 65150976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003728.4", "url": "https://www.ensembl.org/id/ENSSSCT00000003728.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003642.3", "url": "https://www.ensembl.org/id/ENSSSCP00000003642.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QAR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAR1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512473", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512473", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A8WCF8-1", "protein_name": "Tumor protein p63-regulated gene 1-like protein", "gene_name": "Tprg1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLQLRDTVDSAGTSPTAVLAAGEDAGAGRQGAGTPLRQTLWPLNVHDPTRRARVKEYFVFRPGTIEQAVEEIRAVVRPVEDGEIQGVWLLTEVDHWNNEKERLVLVTDQSLLICKYDFISLQCQQVVRVALSAVDTISCGEFQFPPKSLNKREGFGVRIQWDKQSRPSFINRWNPWSTNMPYATFIEHPMAGMDEKTASLCHLESFKALLIQAVKKAQKESPLPGQANNVLVLDRPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 266 }, "evidence": [ { "id": "A0A5G2QRM0", "url": "https://omabrowser.org/oma/group/A0A5G2QRM0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B8A4V5-1", "protein_name": "Tumor protein p63-regulated gene 1-like protein", "gene_name": "tprg1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLQLNDSVITLDPESPGAAVLLSADCDDGLEVSARAGASVACCSSLQTLTPFHVHNPTMRAKVKDYFVFRPGTIEQAVNDIRTVALPSEDGEVLSVWLLAEVDHWNNEKERLVLITERSLLVCKYDFINLQCQQVIRISLNAVDTISIGEFEFPPKSLNKREGTGIRVQWDKRPRASFMNRWNPWSTDIPYATFTEHPMAHADEKVASLCQLENFKTQLIQAVKKAHKEYPIPGRANGVLILERPLLIETYLGIMSFINNEAKLGYAMTRGKIGF", "length": 275 }, "evidence": [ { "id": "A0A5G2QRM0", "url": "https://omabrowser.org/oma/group/A0A5G2QRM0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1P107-1", "protein_name": "Tumor protein p63 regulated 1 like", "gene_name": "TPRG1L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLQLRDPEEGGPEDEEEAAGGAAALLVPGGPEPPFSAAPPRQKLRPLNVRTASRAGRLKEYFVFRPGTIEQAVSEIRAVVMPTEDGDVESVWLLTEIDHWNNEKERLVLITDRSLLICKYDFVGLQCQHVTRIALNAIDTISVGEFEFPPKSLNKREGVGIRIQWDKRSRASFINRWNPWSTNVPYATFTEHPMADADEKVASLCLLENFKTQLIQAVKKAHKEWPLPGRANGVLVLERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 270 }, "evidence": [ { "id": "A0A5G2QRM0", "url": "https://omabrowser.org/oma/group/A0A5G2QRM0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F6QRH3-1", "protein_name": "Tumor protein p63 regulated 1 like", "gene_name": "TPRG1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLQLRDSVDSAGTSPTALLAAGEEVGPGSGGGGGGGRPGVGTPLRQTLWPLSVHDPTRRARVKEYFVFRPGTIEQAVEEIRVVVRPVEDGDIQGVWLLTEVDHWNNEKERLVLITDQALLICKYDFISLQCQQVVRVALNAVDTISYGEFQFPPKSLNKREGFGIRIQWDKQSRPSFISRWNPWSTSVPYTTFIEHPMAGVDEKTASLCQLDGFKALLIQAVKKAQKESPLPGQEGGVLVLECPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 274 }, "evidence": [ { "id": "A0A5G2QRM0", "url": "https://omabrowser.org/oma/group/A0A5G2QRM0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5T0D9-1", "protein_name": "Tumor protein p63-regulated gene 1-like protein", "gene_name": "TPRG1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQLRDSVDSAGTSPTAVLAAGEEVGAGGGPGGGRPGAGTPLRQTLWPLSIHDPTRRARVKEYFVFRPGSIEQAVEEIRVVVRPVEDGEIQGVWLLTEVDHWNNEKERLVLVTEQSLLICKYDFISLQCQQVVRIALNAVDTISYGEFQFPPKSLNKREGFGIRIQWDKQSRPSFINRWNPWSTNVPYATFTEHPMAGADEKTASLCQLESFKALLIQAVKKAQKESPLPGQANGVLILERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 272 }, "evidence": [ { "id": "A0A5G2QRM0", "url": "https://omabrowser.org/oma/group/A0A5G2QRM0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBS2-1", "protein_name": "Tumor protein p63-regulated gene 1-like protein", "gene_name": "Tprg1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLQLRDTVDSAGTSPTAVLAAGEDAGAGRPGAGTPLRQTLWPLNVHDPTRRARVKEYFVFRPGTIEQAVEEIRAVVRPVEDGEIQGVWLLTEVDHWNNEKERLVLVTDQSLLICKYDFISLQCQQVVRVALSAVDTISCGEFQFPPKSLNKREGFGVRIQWDKQSRPSFINRWNPWSTNMPYATFIEHPMAGMDEKTASLCHLESFKALLIQAVKKAQKESPLPGQANTVLVLERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 266 }, "evidence": [ { "id": "A0A5G2QRM0", "url": "https://omabrowser.org/oma/group/A0A5G2QRM0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRM0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRM0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRM0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRM0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRM0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 277, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRM0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRM0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM0" }, { "id": "PS51791", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51791" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSac2", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 242, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQ60-1", "uniprot_ac": "A0A5G2QQ60", "uniprot_id": "A0A5G2QQ60_PIG", "mass": { "chemical_mass": 111476.0, "monoisotopic_mass": 111476.0 }, "refseq": {}, "gene_names": [ { "name": "ADGRG2", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60" } ] } ], "protein_names": [ { "name": "Adhesion G-protein coupled receptor G2", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 64", "type": "synonym", "evidence": [ { "id": "A0A5G2QQ60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ60", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ADGRG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60", "locus": { "chromosome": "X", "start_pos": 15371805, "end_pos": 15463619, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000029756", "url": "https://www.ensembl.org/id/ENSSSCG00000029756" } ] } } ], "crossref": [ { "id": "A0A5G2QQ60", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ60", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000029756", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000029756", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15444", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15444", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011:SF264", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011:SF264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26152", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26152", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QFH9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ60", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ60-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8D4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GPV0", "url": "https://www.uniprot.org/uniprotkb/K7GPV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GPV0-1", "url": "https://www.uniprot.org/uniprotkb/K7GPV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLGGGQYGHVGRLEELLPMFKIVLVVICLHVPLVTSLEEYADNSTLLPPSAESSLVGFVPYSNGTPEVESTSLNDATSSVLSTLNKTEKTKITIVKTFNASGVKPQRNNCNLSSICNDSAFFRGEIMFQYDEEINVTQKQIVANGTLTGILSLGEMKRSELNKTLQTLSETYFIVCATAEAQSTLNCTFTVKLNKTMNICAVMVALPTVKIQPLEQCCCSVRIPCPSSPEELKKLQCDPQDPVACLAGHPHGPPPSSSRNSILFSPPATIVSQLSSAFPFSEPLAHPPVTQSPHSPTREIPLPSPRPSAPIASSPAIDTPPQSRTISSLTSPSDLLDTLPPVKASLPSPITSAAANVITTSTPPDKTEIVHTSSISVSDLENQVSRMEKALSLGSLEPNLAGQMVHQVSNLLHSPPTLLAPLAQRLLRVVDDIGLQLNFSTKTISLTSASLALAVIRVNASNFDTTTFAAQDPAHLQVSLETQAPENSIGAITLPSSLMSNLPANDVALASRVQFNFFETPALFQDPALENLSLISYVISSSIANLTVKNLTRNVTVTLKHVDPSQDDLRVRCVFWDLGRNGGRGGWSSDGCSVKARRLNETTCTCSHLTSFGVLLDLSRTSLPPAQMMVLTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYDIRGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCVVGWGVPAVVVTIVLIISPDNYGLGSYGKFPNGSPDDFCWINSNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSVAGITFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCATKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSSSHSLQSNSNSTHSTTLLVNNDCSGLASGNGTISTEKNGVSFSVQNGDVCLHDFTGKQHMFNEKEDSCNGKSRIALRRTSKRGSLHFIEQM", "length": 1021, "header": "tr|A0A5G2QQ60-1|A0A5G2QQ60_PIG Isoform 1 of Adhesion G-protein coupled receptor G2 OS=Sus scrofa OX=9823 GN=ADGRG2 PE=3 SV=1 CANONICAL=A0A5G2QQ60-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QFH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60/entry#A0A5G2QFH9-1", "sequence": { "sequence": "MLLGGGQYGHVGRLEELLPMFKIVLVVICLHVPLVTSLEEYADNSTLLPPSEVESTSLNDATSSVLSTLNKTGVKPQRNNCNLSSICNDSAFFRGEIMFQYDEEINVTQKQIVANGTLTGILSLGEMKRSELNKTLQTLSETYFIVCATAEAQSTLNCTFTVKLNKTMNICAVMVALPTVKIQPLEQCCCSVRIPCPSSPEELKKLQCDPQDPVACLAGHPHGPPPSSSRNSILFSPPATIVSQLSSAFPFSEPLAHPPVTQSPHSPTREIPLPSPRPSAPIASSPAIDTPPQSRTISSLTSPSDLLDTLPPVKASLPSPITSAAANVITTSTPPDKTEIVHTSSISVSDLENQVSRMEKALSLGSLEPNLAGQMVHQVSNLLHSPPTLLAPLAQRLLRVVDDIGLQLNFSTKTISLTSASLALAVIRVNASNFDTTTFAAQDPAHLQDDLRVRCVFWDLGRNGGRGGWSSDGCSVKARRLNETTCTCSHLTSFGVLLDLSRTSLPPAQMMVLTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYDIRGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCVVGWGVPAVVVTIVLIISPDNYGLGSYGKFPNGSPDDFCWINSNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSVAGITFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCATKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSSSHSLQSNSNSTHSTTLLVNNDCSGLASGNGTISTEKNGVSFSVQNGDVCLHDFTGKQHMFNEKEDSCNGKSRIALRRTSKRGSLHFIEQM", "length": 902, "header": "tr|A0A5G2QFH9-1|A0A5G2QQ60_PIG Computationally mapped isoform of Adhesion G-protein coupled receptor G2 OS=Sus scrofa OX=9823 GN=ADGRG2 PE=3 SV=1 CANONICAL=A0A5G2QQ60-1" }, "locus": { "chromosome": "X", "start_pos": 15452052, "end_pos": 15371808, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081948.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081948.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062966.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062966.1" } ] } }, { "isoform_ac": "A0A5G2QMM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60/entry#A0A5G2QMM3-1", "sequence": { "sequence": "MLLGGGQYGHVGRLEELLPMFKIVLVVICLHVPLVTSLEEYADNSTLLPPSDATSSVLSTLNKTEKTKITIVKTFNASGVKPQRNNCNLSSICNDSAFFRGEIMFQYDEEINVTQKQIVANGTLTGILSLGEMKRSELNKTLQTLSETYFIVCATAEAQSTLNCTFTVKLNKTMNICAVMVALPTVKIQPLEQCCCSVRIPCPSSPEELKKLQCDPQDPVACLAGHPHGPPPSSSRNSILFSPPATIVSQLSSAFPFSEPLAHPPVTQSPHSPTREIPLPSPRPSAPIASSPAIDTPPQSRTISSLTSPSDLLDTLPPVKASLPSPITSAAANVITTSTPPDKTEIVHTSSISVSDLENQVSRMEKALSLGSLEPNLAGQMVHQVSNLLHSPPTLLAPLAQRLLRVVDDIGLQLNFSTKTISLTSASLALAVIRVNASNFDTTTFAAQDPAHLQVSLETQAPENSIGAITLPSSLMSNLPANDVALASRVQFNFFETPALFQDPALENLSLISYVISSSIANLTVKNLTRNVTVTLKHVDPSQDDLRVRCVFWDLGRNGGRGGWSSDGCSVKARRLNETTCTCSHLTSFGVLLDLSRTSLPPAQMMVLTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYDIRGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCVVGWGVPAVVVTIVLIISPDNYGLGSYGKFPNGSPDDFCWINSNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSVAGITFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCATKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSSSHSLQSNSNSTHSTTLLVNNDCSGLASGNGTISTEKNGVSFSVQNGDVCLHDFTGKQHMFNEKEDSCNGKSRIALRRTSKRGSLHFIEQM", "length": 997, "header": "tr|A0A5G2QMM3-1|A0A5G2QQ60_PIG Computationally mapped isoform of Adhesion G-protein coupled receptor G2 OS=Sus scrofa OX=9823 GN=ADGRG2 PE=3 SV=1 CANONICAL=A0A5G2QQ60-1" }, "locus": { "chromosome": "X", "start_pos": 15452052, "end_pos": 15371808, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081182.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081182.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065904.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065904.1" } ] } }, { "isoform_ac": "A0A5G2QPV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60/entry#A0A5G2QPV6-1", "sequence": { "sequence": "MLLGGGQYGHVGRLEELLPMFKIVLVVICLHVPLVTSLEEYADNSTLLPPSAESSLVGFVPYSNGTPEVESTSLNDATSSVLSTLNKTEKTKITIVKTFNASGVKPQRNNCNLSSICNDSAFFRGEIMFQYDEEINVTQKQIVANGTLTGILSLGEMKRSELNKTLQTLSETYFIVCATAEAQSTLNCTFTVKLNKTMNICAVMVALPTVKIQPLEQCCCSVRIPCPSSPEELKKLQCDPQDPVACLAGHPHGPPPSSSRNSILFSPPATIVSQLSSAFPFSEPLAHPPVTQSPHSPTREIPLPSPRPSAPIASSPAIDTPPQSRTISSLTSPSDLLDTLPPVKASLPSPITSAAANVITTSTPPDKTEIVHTSSISVSDLENQVSRMEKALSLGSLEPNLAGQMVHQVSNLLHSPPTLLAPLAQRLLRVVDDIGLQLNFSTKTISLTSASLALAVIRVNASNFDTTTFAAQDPAHLQVSLETQAPENSIGAITLPSSLMSNLPANDVALASRVQFNFFETPALFQDPALENLSLISYVISSSIANLTVKNLTRNVTVTLKHVDPSQDDLRVRCVFWDLGRNGGRGGWSSDGCSVKARRLNETTCTCSHLTSFGVLLDLSRTSLPPAQMMVLTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYDIRGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCVVGWGVPAVVVTIVLIISPDNYGLGSYGKFPNGSPDDFCWINSNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSVAGITFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCATKENVRKQWRRYLCCGKLRLAENSGTISTEKNGVSFSVQNGDVCLHDFTGKQHMFNEKEDSCNGKSRIALRRTSKRGSLHFIEQM", "length": 970, "header": "tr|A0A5G2QPV6-1|A0A5G2QQ60_PIG Computationally mapped isoform of Adhesion G-protein coupled receptor G2 OS=Sus scrofa OX=9823 GN=ADGRG2 PE=3 SV=1 CANONICAL=A0A5G2QQ60-1" }, "locus": { "chromosome": "X", "start_pos": 15452052, "end_pos": 15371808, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068444.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068444.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066930.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066930.1" } ] } }, { "isoform_ac": "A0A5G2QQ60-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60/entry#A0A5G2QQ60-1", "sequence": { "sequence": "MLLGGGQYGHVGRLEELLPMFKIVLVVICLHVPLVTSLEEYADNSTLLPPSAESSLVGFVPYSNGTPEVESTSLNDATSSVLSTLNKTEKTKITIVKTFNASGVKPQRNNCNLSSICNDSAFFRGEIMFQYDEEINVTQKQIVANGTLTGILSLGEMKRSELNKTLQTLSETYFIVCATAEAQSTLNCTFTVKLNKTMNICAVMVALPTVKIQPLEQCCCSVRIPCPSSPEELKKLQCDPQDPVACLAGHPHGPPPSSSRNSILFSPPATIVSQLSSAFPFSEPLAHPPVTQSPHSPTREIPLPSPRPSAPIASSPAIDTPPQSRTISSLTSPSDLLDTLPPVKASLPSPITSAAANVITTSTPPDKTEIVHTSSISVSDLENQVSRMEKALSLGSLEPNLAGQMVHQVSNLLHSPPTLLAPLAQRLLRVVDDIGLQLNFSTKTISLTSASLALAVIRVNASNFDTTTFAAQDPAHLQVSLETQAPENSIGAITLPSSLMSNLPANDVALASRVQFNFFETPALFQDPALENLSLISYVISSSIANLTVKNLTRNVTVTLKHVDPSQDDLRVRCVFWDLGRNGGRGGWSSDGCSVKARRLNETTCTCSHLTSFGVLLDLSRTSLPPAQMMVLTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYDIRGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCVVGWGVPAVVVTIVLIISPDNYGLGSYGKFPNGSPDDFCWINSNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSVAGITFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCATKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSSSHSLQSNSNSTHSTTLLVNNDCSGLASGNGTISTEKNGVSFSVQNGDVCLHDFTGKQHMFNEKEDSCNGKSRIALRRTSKRGSLHFIEQM", "length": 1021, "header": "tr|A0A5G2QQ60-1|A0A5G2QQ60_PIG Isoform 1 of Adhesion G-protein coupled receptor G2 OS=Sus scrofa OX=9823 GN=ADGRG2 PE=3 SV=1 CANONICAL=A0A5G2QQ60-1" }, "locus": { "chromosome": "X", "start_pos": 15452052, "end_pos": 15371808, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068039.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068039.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067031.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067031.1" } ] } }, { "isoform_ac": "A0A5G2QWR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60/entry#A0A5G2QWR7-1", "sequence": { "sequence": "MLLGGGQYGHVGRLEELLPMFKIVLVVICLHVPLVTSLEEYADNSTLLPPSEVESTSLNDATSSVLSTLNKTEKTKITIVKTFNASGVKPQRNNCNLSSICNDSAFFRGEIMFQYDEEINVTQKQIVANGTLTGILSLGEMKRSELNKTLQTLSETYFIVCATAEAQSTLNCTFTVKLNKTMNICAVMVALPTVKIQPLEQCCCSVRIPCPSSPEELKKLQCDPQDPVACLAGHPHGPPPSSSRNSILFSPPATIVSQLSSAFPFSEPLAHPPVTQSPHSPTREIPLPSPRPSAPIASSPAIDTPPQSRTISSLTSPSDLLDTLPPVKASLPSPITSAAANVITTSTPPDKTEIVHTSSISVSDLENQVSRMEKALSLGSLEPNLAGQMVHQVSNLLHSPPTLLAPLAQRLLRVVDDIGLQLNFSTKTISLTSASLALAVIRVNASNFDTTTFAAQDPAHLQVSLETQAPENSIGAITLPSSLMSNLPANDVALASRVQFNFFETPALFQDPALENLSLISYVISSSIANLTVKNLTRNVTVTLKHVDPSQDDLRVRCVFWDLGRNGGRGGWSSDGCSVKARRLNETTCTCSHLTSFGVLLDLSRTSLPPAQMMVLTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYDIRGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCVVGWGVPAVVVTIVLIISPDNYGLGSYGKFPNGSPDDFCWINSNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSVAGITFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCATKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSSSHSLQSNSNSTHSTTLLVNNDCSGLASGNGTISTEKNGVSFSVQNGDVCLHDFTGKQHMFNEKEDSCNGKSRIALRRTSKRGSLHFIEQM", "length": 1005, "header": "tr|A0A5G2QWR7-1|A0A5G2QQ60_PIG Computationally mapped isoform of Adhesion G-protein coupled receptor G2 OS=Sus scrofa OX=9823 GN=ADGRG2 PE=3 SV=1 CANONICAL=A0A5G2QQ60-1" }, "locus": { "chromosome": "X", "start_pos": 15452052, "end_pos": 15371808, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089671.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089671.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066384.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066384.1" } ] } }, { "isoform_ac": "A0A5G2R8D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60/entry#A0A5G2R8D4-1", "sequence": { "sequence": "MLLGGGQYGHVGRLEELLPMFKIVLVVICLHVPLVTSLEEYADNSTLLPPSAESSLVGFVPYSNGTPDATSSVLSTLNKTGVKPQRNNCNLSSICNDSAFFRGEIMFQYDEEINVTQKQIVANGTLTGILSLGEMKRSELNKTLQTLSETYFIVCATAEAQSTLNCTFTVKLNKTMNICAVMVALPTVKIQPLEQCCCSVRIPCPSSPEELKKLQCDPQDPVACLAGHPHGPPPSSSRNSILFSPPATIVSQLSSAFPFSEPLAHPPVTQSPHSPTREIPLPSPRPSAPIASSPAIDTPPQSRTISSLTSPSDLLDTLPPVKASLPSPITSAAANVITTSTPPDKTEIVHTSSISVSDLENQVSRMEKALSLGSLEPNLAGQMVHQVSNLLHSPPTLLAPLAQRLLRVVDDIGLQLNFSTKTISLTSASLALAVIRVNASNFDTTTFAAQDPAHLQVSLETQAPENSIGAITLPSSLMSNLPANDVALASRVQFNFFETPALFQDPALENLSLISYVISSSIANLTVKNLTRNVTVTLKHVDPSQDDLRVRCVFWDLGRNGGRGGWSSDGCSVKARRLNETTCTCSHLTSFGVLLDLSRTSLPPAQMMVLTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYDIRGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCVVGWGVPAVVVTIVLIISPDNYGLGSYGKFPNGSPDDFCWINSNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSVAGITFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCATKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSSSHSLQSNSNSTHSTTLLVNNDCSGLASGNGTISTEKNGVSFSVQNGDVCLHDFTGKQHMFNEKEDSCNGKSRIALRRTSKRGSLHFIEQM", "length": 999, "header": "tr|A0A5G2R8D4-1|A0A5G2QQ60_PIG Computationally mapped isoform of Adhesion G-protein coupled receptor G2 OS=Sus scrofa OX=9823 GN=ADGRG2 PE=3 SV=1 CANONICAL=A0A5G2QQ60-1" }, "locus": { "chromosome": "X", "start_pos": 15452052, "end_pos": 15371808, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089029.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089029.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073528.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073528.1" } ] } }, { "isoform_ac": "K7GPV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60/entry#K7GPV0-1", "sequence": { "sequence": "MLLGGGQYGHVGRLEELLPMFKIVLVVICLHVPLVTSLEEYADNSTLLPPSAESSLVGFVPYSNGTPEVESTSLNDATSSVLSTLNKTGVKPQRNNCNLSSICNDSAFFRGEIMFQYDEEINVTQKQIVANGTLTGILSLGEMKRSELNKTLQTLSETYFIVCATAEAQSTLNCTFTVKLNKTMNICAVMVALPTVKIQPLEQCCCSVRIPCPSSPEELKKLQCDPQDPVACLAGHPHGPPPSSSRNSILFSPPATIVSQLSSAFPFSEPLAHPPVTQSPHSPTREIPLPSPRPSAPIASSPAIDTPPQSRTISSLTSPSDLLDTLPPVKASLPSPITSAAANVITTSTPPDKTEIVHTSSISVSDLENQVSRMEKALSLGSLEPNLAGQMVHQVSNLLHSPPTLLAPLAQRLLRVVDDIGLQLNFSTKTISLTSASLALAVIRVNASNFDTTTFAAQDPAHLQVSLETQAPENSIGAITLPSSLMSNLPANDVALASRVQFNFFETPALFQDPALENLSLISYVISSSIANLTVKNLTRNVTVTLKHVDPSQDDLRVRCVFWDLGRNGGRGGWSSDGCSVKARRLNETTCTCSHLTSFGVLLDLSRTSLPPAQMMVLTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYDIRGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCVVGWGVPAVVVTIVLIISPDNYGLGSYGKFPNGSPDDFCWINSNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSVAGITFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCATKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSSSHSLQSNSNSTHSTTLLVNNDCSGLASGNGTISTEKNGVSFSVQNGDVCLHDFTGKQHMFNEKEDSCNGKSRIALRRTSKRGSLHFIEQM", "length": 1007, "header": "tr|K7GPV0-1|A0A5G2QQ60_PIG Computationally mapped isoform of Adhesion G-protein coupled receptor G2 OS=Sus scrofa OX=9823 GN=ADGRG2 PE=3 SV=3 CANONICAL=A0A5G2QQ60-1" }, "locus": { "chromosome": "X", "start_pos": 15452052, "end_pos": 15371808, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035725.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035725.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029916.3", "url": "https://www.ensembl.org/id/ENSSSCP00000029916.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QFH9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFH9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ60", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ60", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ60", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ60", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ60", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ60", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ60", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ60", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 546, "end_pos": 548, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 775, "end_pos": 777, "annotation": "n_glycosylation_sequon" }, { "start_pos": 805, "end_pos": 807, "annotation": "n_glycosylation_sequon" }, { "start_pos": 861, "end_pos": 863, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" }, { "start_pos": 960, "end_pos": 962, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQ60-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1021, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQ60-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ60" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQ60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60" }, { "id": "PS50261", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 2", "eco_id": "ECO_0000259", "start_pos": 632, "end_pos": 887, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QQ60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ60" }, { "id": "PS50221", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50221" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GAIN-B", "eco_id": "ECO_0000259", "start_pos": 465, "end_pos": 623, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 112, "end_pos": 114 }, { "start_pos": 118, "end_pos": 120 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 145, "end_pos": 147 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 187, "end_pos": 189 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 532, "end_pos": 534 }, { "start_pos": 546, "end_pos": 548 }, { "start_pos": 551, "end_pos": 553 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 64, "end_pos": 66 }, { "start_pos": 775, "end_pos": 777 }, { "start_pos": 805, "end_pos": 807 }, { "start_pos": 861, "end_pos": 863 }, { "start_pos": 86, "end_pos": 88 }, { "start_pos": 940, "end_pos": 942 }, { "start_pos": 960, "end_pos": 962 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QPS5-1", "uniprot_ac": "A0A5G2QPS5", "uniprot_id": "A0A5G2QPS5_PIG", "mass": { "chemical_mass": 117857.0, "monoisotopic_mass": 117857.0 }, "refseq": {}, "gene_names": [ { "name": "FARP1", "type": "recommended", "evidence": [ { "id": "A0A5G2QPS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" } ] } ], "protein_names": [ { "name": "FERM, ARHGEF and pleckstrin domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2QPS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5/entry#names_and_taxonomy" } ] }, { "name": "FERM, RhoGEF and pleckstrin domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A5G2QPS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FARP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5", "locus": { "chromosome": "11", "start_pos": 67457548, "end_pos": 67144645, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026863", "url": "https://www.ensembl.org/id/ENSSSCG00000026863" } ] } } ], "crossref": [ { "id": "A0A5G2QPS5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QPS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026863", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026863", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01220", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01220", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13193", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13193", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13235", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13235", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17189", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17189", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000798", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000798", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45858", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45858", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45858:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45858:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QPS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9Q6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGJ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEIEQRPTPGSRLGAPENSGISTLEHGQKPPPTPSGKLMSIKIQMLDDTQEAFEVPQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVGDVRPKHVVVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEASDREHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDVNSSYQDTLEFLMASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDFVREGGHKKVPFERKHSKIHSIRSLATEPTEPNSEVPKQAQPSASLTLGEGAESPGSGQSCQQGEDLSGATQERSPALQRSPAAAAVAVAAAGSKDADRAVKAVMEEEEEVVKDRTQQSRPQPQQPSTGSQTGSPHLSELSINSQGGAAPTNAILSPNLSPDTKQASPLVSPLLNDQAGPRTDDEDDGRRKRFPTDKAYFIAKEVSTTERTYLKDLEVITSWFQSAVSKEDSMPETLRSLIFPNFEPLHKFHTNFLKEIEQRLALWEGRSNAHIRGDFYQRIGDVMLKNIQGMKQLAAHLWKHSEALEALETSIRGSRRLESLCRDFELQKVCYLPLNTFLLRPLHRLMHYKQVLERLCKHHPPSHADFRDCRAALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGVDNLVIPGREFIRLGSLSKLSGKGLQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTMEESEDEWGVPHCLTLRGQRQSIIVAASSRSEMEKWVEDIQMAIDLAEKSSDPAPEFLASSPPDNKSPEEAAVDQESEDDLSASRTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSVAVENQLSGNLLRKFKNSNGWQKLWVVFTNFCLFFYKSPQDNHPLASLPLLGYSLTVPSEAEDIHKDYVFKLHFKSHVYYFRAESEYTFERWMEVIRSATSSASRAHVLSHKESHVY", "length": 1042, "header": "tr|A0A5G2QPS5-1|A0A5G2QPS5_PIG Isoform 1 of FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Sus scrofa OX=9823 GN=FARP1 PE=1 SV=1 CANONICAL=A0A5G2QPS5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QPS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5/entry#A0A5G2QPS5-1", "sequence": { "sequence": "MGEIEQRPTPGSRLGAPENSGISTLEHGQKPPPTPSGKLMSIKIQMLDDTQEAFEVPQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVGDVRPKHVVVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEASDREHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDVNSSYQDTLEFLMASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDFVREGGHKKVPFERKHSKIHSIRSLATEPTEPNSEVPKQAQPSASLTLGEGAESPGSGQSCQQGEDLSGATQERSPALQRSPAAAAVAVAAAGSKDADRAVKAVMEEEEEVVKDRTQQSRPQPQQPSTGSQTGSPHLSELSINSQGGAAPTNAILSPNLSPDTKQASPLVSPLLNDQAGPRTDDEDDGRRKRFPTDKAYFIAKEVSTTERTYLKDLEVITSWFQSAVSKEDSMPETLRSLIFPNFEPLHKFHTNFLKEIEQRLALWEGRSNAHIRGDFYQRIGDVMLKNIQGMKQLAAHLWKHSEALEALETSIRGSRRLESLCRDFELQKVCYLPLNTFLLRPLHRLMHYKQVLERLCKHHPPSHADFRDCRAALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGVDNLVIPGREFIRLGSLSKLSGKGLQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTMEESEDEWGVPHCLTLRGQRQSIIVAASSRSEMEKWVEDIQMAIDLAEKSSDPAPEFLASSPPDNKSPEEAAVDQESEDDLSASRTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSVAVENQLSGNLLRKFKNSNGWQKLWVVFTNFCLFFYKSPQDNHPLASLPLLGYSLTVPSEAEDIHKDYVFKLHFKSHVYYFRAESEYTFERWMEVIRSATSSASRAHVLSHKESHVY", "length": 1042, "header": "tr|A0A5G2QPS5-1|A0A5G2QPS5_PIG Isoform 1 of FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Sus scrofa OX=9823 GN=FARP1 PE=1 SV=1 CANONICAL=A0A5G2QPS5-1" }, "locus": { "chromosome": "11", "start_pos": 67456218, "end_pos": 67216852, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077124.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077124.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060292.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060292.1" } ] } }, { "isoform_ac": "A0A5G2R9Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5/entry#A0A5G2R9Q6-1", "sequence": { "sequence": "LWYLAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVGDVRPKHVVVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEASDREHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDVNSSYQDTLEFLMASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDFVREGGHKKVPFERKHSKIHSIRSLATEPTEPNSEVPKQAQPSASLTLGEGAESPGSGQSCQQGEDLSGATQERSPALQRSPAAAAVAVAAAGSKDADRAVKAVMEEEEEVVKDRTQQSRPQPQQPSTGSQTGSPHLSELSINSQGGAAPTNAILSPNLSPDTKQASPLVSPLLNDQAGPRTDDEDDGRRKRFPTDKAYFIAKEVSTTERTYLKDLEVITSWFQSAVSKEDSMPETLRSLIFPNFEPLHKFHTNFLKEIEQRLALWEGRSNAHIRGDFYQRIGDVMLKNIQGMKQLAAHLWKHSEALEALETSIRGSRRLESLCRDFELQKVCYLPLNTFLLRPLHRLMHYKQVLERLCKHHPPSHADFRDCRAALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGVDNLVIPGREFIRLGSLSKLSGKGLQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTMEESEDEWGVPHCLTLRGQRQSIIVAASSRSEMEKWVEDIQMAIDLAEKSSDPAPEFLASSPPDNKSPEEAAVDQESEDDLSASRTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSVAVENQLSGNLLRKFKNSNGWQKLWVVFTNFCLFFYKSPQDNHPLASLPLLGYSLTVPSEAEDIHKDYVFKLHFKSHVYYFRAESEYTFERWMEVIRSATSSASRAHVLSHKESHVY", "length": 987, "header": "tr|A0A5G2R9Q6-1|A0A5G2R9Q6_PIG Computationally mapped isoform of FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Sus scrofa OX=9823 GN=FARP1 PE=1 SV=1 CANONICAL=A0A5G2QPS5-1" }, "locus": { "chromosome": "11", "start_pos": 67456218, "end_pos": 67343272, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078090.1", "url": "https://www.ensembl.org/id/ENSSSCT00000078090.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073049.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073049.1" } ] } }, { "isoform_ac": "A0A5G2RGJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5/entry#A0A5G2RGJ1-1", "sequence": { "sequence": "MGEIEQRPTPGSRLGAPENSGISTLEHGQKPPPTPSGKLMSIKIQMLDDTQEAFEVPQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEASDREHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDVNSSYQDTLEFLMASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDFVREGGHKKVPFERKHSKIHSIRSLATEPTEPNSEVPKQAQPSASLTLGEGAESPGSGQSCQQGEDLSGATQERSPALQRSPAAAAVAVAAAGSKDADRAVKAVMEEEEEVVKDRTQQSRPQPQQPSTGPASRAARGSSASILLREHASRSRSQTNDNYEGDVTSGVYLLSREERSREARHRASPRSAKSSRPPSRGFLDDDSADITFDTSGSPRLPRHSSLIDELFRGPGSHSPLATPLSPSSRSSSPDVSWDRTGSQGYVSESGHGWREPSTGEGTLSSRDPLCENASPVLQRPHVRDLPSRCNKSETDPLILSQVAATPEAVDVLDSRGKGGLASLAGPQGRTLANGTRLIGPRAKSPITQAACARPWPAQQAPLQKTEGSTSSGSESSDSDSEMLNPLGQPLVFGNPAALSSPSRARGQKCSGGLHLNEETEEDE", "length": 788, "header": "tr|A0A5G2RGJ1-1|A0A5G2QPS5_PIG Computationally mapped isoform of FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Sus scrofa OX=9823 GN=FARP1 PE=1 SV=1 CANONICAL=A0A5G2QPS5-1" }, "locus": { "chromosome": "11", "start_pos": 67396097, "end_pos": 67216852, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086113.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086113.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074123.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074123.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGJ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGJ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-SSC-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" } ], "pmid": "" }, { "name": "filopodium", "id": "GO:0030175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030175", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Rac protein signal transduction", "id": "GO:0016601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016601", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" } ], "pmid": "" }, { "name": "enzyme-linked receptor protein signaling pathway", "id": "GO:0007167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007167", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" } ], "pmid": "" }, { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 874, "end_pos": 876, "annotation": "n_glycosylation_sequon" }, { "start_pos": 916, "end_pos": 918, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QPS5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1042, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QPS5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QPS5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QPS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 536, "end_pos": 728, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QPS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" }, { "id": "PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 310, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QPS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPS5" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 757, "end_pos": 854, "start_aa": "Glu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 34 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 497, "end_pos": 499 }, { "start_pos": 874, "end_pos": 876 }, { "start_pos": 916, "end_pos": 918 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QPT8-1", "uniprot_ac": "A0A5G2QPT8", "uniprot_id": "A0A5G2QPT8_PIG", "mass": { "chemical_mass": 42025.0, "monoisotopic_mass": 42025.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100523770", "type": "recommended", "evidence": [ { "id": "A0A5G2QPT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8" } ] } ], "protein_names": [ { "name": "Peptidase A1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QPT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPT8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100523770", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QPT8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QPT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47966:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47966:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QPT8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY51-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RIE6", "url": "https://www.uniprot.org/uniprotkb/F1RIE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RIE6-1", "url": "https://www.uniprot.org/uniprotkb/F1RIE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWCSGTTFLLHLLLGFAAALSPLLCLIPLTKVKSIRENLREKGLLKNFLKEHPFNMIQNRLNQKPAPQGKVSRQPLRNYFDMAYVGNISIGTPPQQFSVIFDTGSSDLWVPSIYCQSRACNTHRVFDPFKSTTFRYSGVPIELEYASGMMSGYLGYDTVRVMWTPQDQEFGYSQWEENEAFDHAMFDGMLGLGYPGLIAQPVFAFYLSTNKEEGSVVMFGGVDRSFYKGELKWVPLTKPNYWQIALDRITWRGYVVACKSGCQAVIDTGSSLLIGPTKEVINIQKLINFLIQCSTMNTLPDFIFTINNVQYPVPARAYIQKGSSTGRCYSNFSGGTEDLSDKEFWILGDVFLRLYFTVFDRGQDRIGLAPAV", "length": 372, "header": "tr|A0A5G2QPT8-1|A0A5G2QPT8_PIG Isoform 1 of Peptidase A1 domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100523770 PE=3 SV=2 CANONICAL=A0A5G2QPT8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QPT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8/entry#A0A5G2QPT8-1", "sequence": { "sequence": "MWCSGTTFLLHLLLGFAAALSPLLCLIPLTKVKSIRENLREKGLLKNFLKEHPFNMIQNRLNQKPAPQGKVSRQPLRNYFDMAYVGNISIGTPPQQFSVIFDTGSSDLWVPSIYCQSRACNTHRVFDPFKSTTFRYSGVPIELEYASGMMSGYLGYDTVRVMWTPQDQEFGYSQWEENEAFDHAMFDGMLGLGYPGLIAQPVFAFYLSTNKEEGSVVMFGGVDRSFYKGELKWVPLTKPNYWQIALDRITWRGYVVACKSGCQAVIDTGSSLLIGPTKEVINIQKLINFLIQCSTMNTLPDFIFTINNVQYPVPARAYIQKGSSTGRCYSNFSGGTEDLSDKEFWILGDVFLRLYFTVFDRGQDRIGLAPAV", "length": 372, "header": "tr|A0A5G2QPT8-1|A0A5G2QPT8_PIG Isoform 1 of Peptidase A1 domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100523770 PE=3 SV=2 CANONICAL=A0A5G2QPT8-1" }, "locus": { "chromosome": "2", "start_pos": 10501265, "end_pos": 10492914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074406.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074406.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066910.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066910.2" } ] } }, { "isoform_ac": "A0A5G2QY51-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8/entry#A0A5G2QY51-1", "sequence": { "sequence": "MPGKFSVVTVILQNGQLLPISYLFPFPMHGERIPLTKVKSIRENLREKGLLKNFLKEHPFNMIQNRLNQKPAPQGKVSRQPLRNYFDMAYVGNISIGTPPQQFSVIFDTGSSDLWVPSIYCQSRACNTHRVFDPFKSTTFRYSGVPIELEYASGMMSGYLGYDTVRVMWTPQDQEFGYSQWEENEAFDHAMFDGMLGLGYPGLIAQPVFAFYLKEGSVVMFGGVDRSFYKGELKWVPLTKPNYWQIALDRITWRGYVVACKSGCQAVIDTGSSLLIGPTKEVINIQKLINAKPFQEEVRNFPQGHSGALHSGRIKFWILGDVFLRLYFTVFDRGQDRIGLAPAV", "length": 344, "header": "tr|A0A5G2QY51-1|A0A5G2QY51_PIG Computationally mapped isoform of Peptidase A1 domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100523770 PE=3 SV=2 CANONICAL=A0A5G2QPT8-1" }, "locus": { "chromosome": "2", "start_pos": 10500290, "end_pos": 10492914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070593.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070593.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069846.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069846.2" } ] } }, { "isoform_ac": "F1RIE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8/entry#F1RIE6-1", "sequence": { "sequence": "MLWLWCRIPLTKVKSIRENLREKGLLKNFLKEHPFNMIQNRLNQKPAPQGKVSRQPLRNYFDMAYVGNISIGTPPQQFSVIFDTGSSDLWVPSIYCQSRACNTHRVFDPFKSTTFRYSGVPIELEYASGMMSGYLGYDTVRISNLIIMGQEFGYSQWEENEAFDHAMFDGMLGLGYPGLIAQPVFAFYLSTNKEEGSVVMFGGVDRSFYKGELKWVPLTKPNYWQIALDRITWRGYVVACKSGCQAVIDTGSSLLIGPTKEVINIQKLINAKPFQEEFLIQCSTMNTLPDFIFTINNVQYPVPARAYIQKVRGQPRGNFSGGTEDLSDKEFWILGDVFLRLYFTVFDRGQDRIGLAPAV", "length": 359, "header": "tr|F1RIE6-1|A0A5G2QPT8_PIG Computationally mapped isoform of Peptidase A1 domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100523770 PE=3 SV=5 CANONICAL=A0A5G2QPT8-1" }, "locus": { "chromosome": "2", "start_pos": 10500454, "end_pos": 10492914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014309.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014309.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013923.4", "url": "https://www.ensembl.org/id/ENSSSCP00000013923.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 277, "start_aa": "Thr", "end_pos": 277, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr277", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RIE6", "url": "https://www.uniprot.org/uniprotkb/F1RIE6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPT8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPT8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPT8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QPT8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 372, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QPT8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QPT8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QPT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT8" }, { "id": "PS51767", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51767" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase A1", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 369, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 277 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 331, "end_pos": 333 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QPT9-1", "uniprot_ac": "A0A5G2QPT9", "uniprot_id": "A0A5G2QPT9_PIG", "mass": { "chemical_mass": 35717.0, "monoisotopic_mass": 35717.0 }, "refseq": { "ac": "XP_020937763", "name": "olfactory receptor 6C6-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937763" }, "gene_names": [ { "name": "LOC100514232", "type": "recommended", "evidence": [ { "id": "A0A5G2QPT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9" } ] }, { "name": "LOC100514232", "type": "synonym", "evidence": [ { "id": "XP_020937763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937763" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QPT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6C6-like", "type": "synonym", "evidence": [ { "id": "XP_020937763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937763" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100514232", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9", "locus": {} } ], "crossref": [ { "id": "A0A5G2QPT9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QPT9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100514232", "url": "https://www.ncbi.nlm.nih.gov/gene/100514232", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514232", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514232", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QPT9", "url": "https://www.orthodb.org/?gene=A0A5G2QPT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020937763", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937763", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QPT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNLSVEIDFILLGLTDDPQLQIMIFLFLFFNYVLSLMGNFIIILLTLLNPHLKTPMYFFLRNFSFLEISFTTVCIPRFLISILTGDKSISYNGCAAQLFFFLLLGVTEFYLLAAMSYDRYVAICKPLRYPVIMNSRVCHQLVLSSWVTGFLIIFPPLALGLQLDFCASKIIDHFLCDSSPILQLSCTDTHNLELASFVLAVVTLVVTLLLVVLSYTYIIKTILKFPSAQQRTKAFSTCSSHMVVVSITYGSCIFMYMKPSAKERVTLTKGVAVLNTSVAPLLNPFIYTLRNQQVKEALKDVLQRFCQFQKKMR", "length": 314, "header": "tr|A0A5G2QPT9-1|A0A5G2QPT9_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100514232 PE=3 SV=1 CANONICAL=A0A5G2QPT9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QPT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9/entry#A0A5G2QPT9-1", "sequence": { "sequence": "MKNLSVEIDFILLGLTDDPQLQIMIFLFLFFNYVLSLMGNFIIILLTLLNPHLKTPMYFFLRNFSFLEISFTTVCIPRFLISILTGDKSISYNGCAAQLFFFLLLGVTEFYLLAAMSYDRYVAICKPLRYPVIMNSRVCHQLVLSSWVTGFLIIFPPLALGLQLDFCASKIIDHFLCDSSPILQLSCTDTHNLELASFVLAVVTLVVTLLLVVLSYTYIIKTILKFPSAQQRTKAFSTCSSHMVVVSITYGSCIFMYMKPSAKERVTLTKGVAVLNTSVAPLLNPFIYTLRNQQVKEALKDVLQRFCQFQKKMR", "length": 314, "header": "tr|A0A5G2QPT9-1|A0A5G2QPT9_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100514232 PE=3 SV=1 CANONICAL=A0A5G2QPT9-1" }, "locus": { "chromosome": "AEMK02000522.1", "start_pos": 281938, "end_pos": 280997, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052597.2", "url": "https://www.ensembl.org/id/ENSSSCT00000052597.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064089.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064089.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514232", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514232", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QPT9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QPT9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QPT9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QPT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 276, "end_pos": 278 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QPU9-1", "uniprot_ac": "A0A5G2QPU9", "uniprot_id": "A0A5G2QPU9_PIG", "mass": { "chemical_mass": 41464.0, "monoisotopic_mass": 41464.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110259249", "type": "recommended", "evidence": [ { "id": "A0A5G2QPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9" } ] } ], "protein_names": [ { "name": "Peptidase A1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259249", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9", "locus": {} } ], "crossref": [ { "id": "A0A5G2QPU9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QPU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47966:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47966:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QPU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RIE4", "url": "https://www.uniprot.org/uniprotkb/F1RIE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RIE4-1", "url": "https://www.uniprot.org/uniprotkb/F1RIE4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLGFVQIPLTKVKSVRESLREKGLLKNFLKEHPYKMIQNQKIACHPLRNYLDMAYVGNITIGTPPQQFSVVFDTGSADLWVPSVYCKSKACVTHRSFKPARSSTFRLPGKNFELEYGSGKISGFLGYDTVRIGRLRTMNQVFGLSQLETGEAFEHGVFDGLLGLGFPSLALKGTTPIFDNLKKQGQISEPVFAFYLSTKEEGSAVIFGGVKKCCYKGELKWVPLTKPHYWQIALDRITWRGHIIGCLRGCQAIVDTGTTYLLGPYAEVDKIHSLMNAVPLQEEYLVQCNARDTYPDIVFTINNVDYPVPARTYIRKDANNNLCYSTFEVMGDTLTESQTWILGDVFLKVYFTVFDRGQNRIGLARAA", "length": 369, "header": "tr|A0A5G2QPU9-1|A0A5G2QPU9_PIG Isoform 1 of Peptidase A1 domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110259249 PE=3 SV=1 CANONICAL=A0A5G2QPU9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QPU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9/entry#A0A5G2QPU9-1", "sequence": { "sequence": "MALLGFVQIPLTKVKSVRESLREKGLLKNFLKEHPYKMIQNQKIACHPLRNYLDMAYVGNITIGTPPQQFSVVFDTGSADLWVPSVYCKSKACVTHRSFKPARSSTFRLPGKNFELEYGSGKISGFLGYDTVRIGRLRTMNQVFGLSQLETGEAFEHGVFDGLLGLGFPSLALKGTTPIFDNLKKQGQISEPVFAFYLSTKEEGSAVIFGGVKKCCYKGELKWVPLTKPHYWQIALDRITWRGHIIGCLRGCQAIVDTGTTYLLGPYAEVDKIHSLMNAVPLQEEYLVQCNARDTYPDIVFTINNVDYPVPARTYIRKDANNNLCYSTFEVMGDTLTESQTWILGDVFLKVYFTVFDRGQNRIGLARAA", "length": 369, "header": "tr|A0A5G2QPU9-1|A0A5G2QPU9_PIG Isoform 1 of Peptidase A1 domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110259249 PE=3 SV=1 CANONICAL=A0A5G2QPU9-1" }, "locus": { "chromosome": "2", "start_pos": 10289742, "end_pos": 10280976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087009.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087009.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060312.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060312.1" } ] } }, { "isoform_ac": "A0A8W4FEE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9/entry#A0A8W4FEE2-1", "sequence": { "sequence": "MALLGFVQIPLTKVKSVRESLREKGLLKNFLKEHPYKMIQNQKIACHPLRNYLDMAYVGNITIGTPPQQFSVVFDTGSADLWVPSVYCKSKACVTHRSFKPARSSTFRLPGFLGYDTVRIGRLRTMNQVFGLSQLETGEAFEHGVFDGLLGLGFPSLALKGTTPIFDNLKKQGQISEPVFAFYLSTKEEGSAVIFGGVKKCCYKGELKWVPLTKPHYWQIALDRITWRGHIIGCLRGCQAIVDTGTTYLLGPYAEVDKIHSLMNAVPLQEEYLVQCNARDTYPDIVFTINNVDYPVPARTYIRKDANNNLCYSTFEVMGDTLTESQTWILGDVFLKVYFTVFDRGQNRIGLARAA", "length": 355, "header": "tr|A0A8W4FEE2-1|A0A5G2QPU9_PIG Computationally mapped isoform of Peptidase A1 domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110259249 PE=3 SV=1 CANONICAL=A0A5G2QPU9-1" }, "locus": { "chromosome": "2", "start_pos": 10289742, "end_pos": 10280976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094693.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094693.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077679.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077679.1" } ] } }, { "isoform_ac": "F1RIE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9/entry#F1RIE4-1", "sequence": { "sequence": "MALLGFVQIPLTKVKSVRESLREKGLLKNFLKEHPYKMIQNQKIACHPLRNYLDMAYVGNITIGTPPQQFSVVFDTGSADLWVPSVYCKSKACVTHRSFKPARSSTFRLPGKNFELEYGSGKISGFLGYDTVRIGRLRTMNQVFGLSQLETGEAFEHGVFDGLLGLGFPSLALKGTTPIFDNLKKQGQISEPVFAFYLSTKEEGSAVIFGGVKKCCYKGELKWVPLTKPHYWQIALDRITWRGHIIGCLRGCQAIVDTGTTYLLGPYAEVDKIHSLMNAVPLQEEYLVQCNARDTYPDIVFTINNVDYPVPARTYIRKVRGQPWGCRSGYRGWAASQTWILGDVFLKVYFTVFDRGQNRIGLARAA", "length": 366, "header": "tr|F1RIE4-1|A0A5G2QPU9_PIG Computationally mapped isoform of Peptidase A1 domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110259249 PE=3 SV=3 CANONICAL=A0A5G2QPU9-1" }, "locus": { "chromosome": "2", "start_pos": 10289742, "end_pos": 10280976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014311.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014311.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013925.4", "url": "https://www.ensembl.org/id/ENSSSCP00000013925.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEE2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QPU9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 369, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QPU9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QPU9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPU9" }, { "id": "PS51767", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51767" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase A1", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 366, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QPX3-1", "uniprot_ac": "A0A5G2QPX3", "uniprot_id": "A0A5G2QPX3_PIG", "mass": { "chemical_mass": 120216.0, "monoisotopic_mass": 120216.0 }, "refseq": {}, "gene_names": [ { "name": "SEMA5A", "type": "recommended", "evidence": [ { "id": "A0A5G2QPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3" } ] } ], "protein_names": [ { "name": "Semaphorin-5A", "type": "recommended", "evidence": [ { "id": "A0A5G2QPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3/entry#names_and_taxonomy" } ] }, { "name": "Semaphorin-F", "type": "synonym", "evidence": [ { "id": "A0A5G2QPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3#function" }, { "database": "UniProtKB", "id": "ARBA00056685", "url": "https://www.uniprot.org/uniprotkb/ARBA00056685#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SEMA5A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3", "locus": { "chromosome": "16", "start_pos": 73328981, "end_pos": 72756383, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017095", "url": "https://www.ensembl.org/id/ENSSSCG00000017095" } ] } } ], "crossref": [ { "id": "A0A5G2QPX3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QPX3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017095", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017095", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057563", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057563", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036:SF78", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036:SF78", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23260", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23260", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-416700", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416700", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5173214", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5173214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QPX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGPCIIAWLFSSLGWWRLAQPETDASQCQRAEHPVISYKEIGPWLREFRAKNAVDFSQLTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKTKEECQNYIRVLLVGGDRLFTCGTNAFTPVCTNRTLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELYAATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDLGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQGTFFLPELDLIYAVFSTNVNSIAASAVCVFNLSAISQAFNGPFKYQENSRSAWLPYPNPNPNFQCGTVDQGLYVNLTERNLQDAQKFILMHEVVQPVTAVPSFMEDNSRFSHVAVDVVQGRDALVHIIYLATDYGSIKKVRAPLTQSSGGCLLEEIELFPERRPEPIRSLQILHSQSVLFVGLREHVAKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSIATCPTRNLTVDGRFGAWSPWTPCSHTDGSAVGSCLCRTRSCDSPAPQCGGWPCEGPRVEIANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHVFWTGWGPWERCTAQCGGGIQARRRTCENGPDCGCNVEYQPCNTNPCPELKKTTPWTPWTPVNISDNGGHYEQRFRYTCKARLPDPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGLPCLGPSLEYQECNILPCPVDGMWSCWSPWSKCSATCGGGHYMRTRSCTNPAPAYGGDICLGLHTEEALCNTQPCPESWSEWSDWSECDVSGVQIRVRQCVLLYPVGGQCSGNTTESRPCVFDSNFIPEVSVARSSSIEEKRCGEFSVFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVAPAPLNTSITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY", "length": 1072, "header": "tr|A0A5G2QPX3-1|A0A5G2QPX3_PIG Isoform 1 of Semaphorin-5A OS=Sus scrofa OX=9823 GN=SEMA5A PE=4 SV=1 CANONICAL=A0A5G2QPX3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QPX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3/entry#A0A5G2QPX3-1", "sequence": { "sequence": "MKGPCIIAWLFSSLGWWRLAQPETDASQCQRAEHPVISYKEIGPWLREFRAKNAVDFSQLTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKTKEECQNYIRVLLVGGDRLFTCGTNAFTPVCTNRTLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELYAATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDLGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQGTFFLPELDLIYAVFSTNVNSIAASAVCVFNLSAISQAFNGPFKYQENSRSAWLPYPNPNPNFQCGTVDQGLYVNLTERNLQDAQKFILMHEVVQPVTAVPSFMEDNSRFSHVAVDVVQGRDALVHIIYLATDYGSIKKVRAPLTQSSGGCLLEEIELFPERRPEPIRSLQILHSQSVLFVGLREHVAKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSIATCPTRNLTVDGRFGAWSPWTPCSHTDGSAVGSCLCRTRSCDSPAPQCGGWPCEGPRVEIANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHVFWTGWGPWERCTAQCGGGIQARRRTCENGPDCGCNVEYQPCNTNPCPELKKTTPWTPWTPVNISDNGGHYEQRFRYTCKARLPDPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGLPCLGPSLEYQECNILPCPVDGMWSCWSPWSKCSATCGGGHYMRTRSCTNPAPAYGGDICLGLHTEEALCNTQPCPESWSEWSDWSECDVSGVQIRVRQCVLLYPVGGQCSGNTTESRPCVFDSNFIPEVSVARSSSIEEKRCGEFSVFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVAPAPLNTSITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY", "length": 1072, "header": "tr|A0A5G2QPX3-1|A0A5G2QPX3_PIG Isoform 1 of Semaphorin-5A OS=Sus scrofa OX=9823 GN=SEMA5A PE=4 SV=1 CANONICAL=A0A5G2QPX3-1" }, "locus": { "chromosome": "16", "start_pos": 73327588, "end_pos": 72985097, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069586.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069586.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060337.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060337.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-416700", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416700", "resource": "Reactome", "description": "Other semaphorin interactions" }, { "id": "R-SSC-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3" } ], "pmid": "" }, { "name": "chemorepellent activity", "id": "GO:0045499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045499", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3" } ], "pmid": "" }, { "name": "axon extension", "id": "GO:0048675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048675", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1013, "end_pos": 1015, "annotation": "n_glycosylation_sequon" }, { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 715, "end_pos": 717, "annotation": "n_glycosylation_sequon" }, { "start_pos": 931, "end_pos": 933, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QPX3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1072, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QPX3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QPX3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPX3" }, { "id": "PS51004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sema", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 483, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1013, "end_pos": 1015 }, { "start_pos": 141, "end_pos": 143 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 322, "end_pos": 324 }, { "start_pos": 366, "end_pos": 368 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 590, "end_pos": 592 }, { "start_pos": 715, "end_pos": 717 }, { "start_pos": 931, "end_pos": 933 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVJ5-1", "uniprot_ac": "A0A5G2QVJ5", "uniprot_id": "A0A5G2QVJ5_PIG", "mass": { "chemical_mass": 162128.0, "monoisotopic_mass": 162128.0 }, "refseq": {}, "gene_names": [ { "name": "ARAP1", "type": "recommended", "evidence": [ { "id": "A0A5G2QVJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ] } ], "protein_names": [ { "name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2QVJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5/entry#names_and_taxonomy" } ] }, { "name": "Centaurin-delta-2", "type": "synonym", "evidence": [ { "id": "A0A5G2QVJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARAP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5", "locus": { "chromosome": "9", "start_pos": 7238049, "end_pos": 7301086, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014817", "url": "https://www.ensembl.org/id/ENSSSCG00000014817" } ] } } ], "crossref": [ { "id": "A0A5G2QVJ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014817", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014817", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08837", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08837", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09490", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09490", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13253", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13253", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13254", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13254", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13256", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13256", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13259", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13259", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45899:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45899:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8849469", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8849469", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QQ18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ18-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LPU3", "url": "https://www.uniprot.org/uniprotkb/I3LPU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LPU3-1", "url": "https://www.uniprot.org/uniprotkb/I3LPU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAGDAALSVAEWLRALHLEQYARLFEQHGLVWATECQGLSDARLVDMGVLLPGHRRRILAGLLRAHTPPAPAPRPAPRPVPMKRHVFRSPPVPAAPPEPLPTAGEDEGLPTAPPIPPRRSCIPPACFSTPSAAAPDPVLPPLPAKRHLPEQCVPPVPPRTGPPRPLVSLPTKEKELLLPPASSPPQPGPEEPPAVFPRGPPQPPTPPPSPPAIPPKPLRPLPEFDDSDYDEVPEEGPGAPAAVMTKKEERPASQVPRAVRVASLLSEGEELSGDDPGDEDEDDHAYEGVPNGGWHTSSLSSALPGSLLTPELPPPPMDGPPVSQDPSPVPPVIKAGWLDKNPPQGSYIYQKRWVRLDASYLQYFDSNKDAYSKRFVPVACISRVAAIGDQKFEVITNNRTFAFRAESDAERKEWIQALQQAVAEQRARARLSSAYPLGGGSEPPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEAADRRSFDLTTPYRIFSFSAESELEKEQWLEAMQGAIAEALSTSEVAERIWAVAPNRFCADCEAAQPDWASINLCVVICKRCAGAHRGLGAGVSKVRSLKMDRKVWTEVLIELFLQLGNAAGNHFWAANVPPSEALQPSSSPSARRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTSDLAETQALLGCGASVNCFSGDPGAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKPLQDRRAREEFSRRWCVLSDGVLSYYENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLENAELAREWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLTGSELHAVFPEGPCEEPLQLRKLQELSVQGDSENQVLVLVERRRTLYIQGERRLDFTGWLGAIQKAAASSGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVRLKEGEQHVDDVSSALKRFLRDLPDGLFTRVQRLSWLEASEIEDEEEKISRYRELLARLPPVNRATVKALISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTDGQDYKAGRVVEDLISRYVVVFSVDEEELRKQRDEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAEAEQHIKIPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSYLVVKKHQSMEAMLLYLASHVGETKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSQRPWSGAPETSHRPEKEWPVRSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCETQMELREWFATFLFMQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFAADPLSLLRNV", "length": 1456, "header": "tr|A0A5G2QVJ5-1|A0A5G2QVJ5_PIG Isoform 1 of Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Sus scrofa OX=9823 GN=ARAP1 PE=1 SV=3 CANONICAL=A0A5G2QVJ5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQ18-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5/entry#A0A5G2QQ18-1", "sequence": { "sequence": "MTKKEERPASQVPRAVRVASLLSEGEELSGDDPGDEDEDDHAYEGVPNGGWHTSSLSSALPGSLLTPELPPPPMDGPPVSQDPSPVPPVIKAGWLDKNPPQGSYIYQKRWVRLDASYLQYFDSNKDAYSKRFVPVACISRVAAIGDQKFEVITNNRTFAFRAESDAERKEWIQALQQAVAEQRARARLSSAYPLGGGSEPPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEAADRRSFDLTTPYRIFSFSAESELEKEQWLEAMQGAIAEALSTSEVAERIWAVAPNRFCADCEAAQPDWASINLCVVICKRCAGAHRGLGAGVSKVRSLKMDRKVWTEVLIELFLQLGNAAGNHFWAANVPPSEALQPSSSPSARRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTSDLAETQALLGCGASVNCFSGDPGAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKPLQDRRAREEFSRRWCVLSDGVLSYYENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLENAELAREWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLTGSELHAVFPEGPCEEPLQLRKLQELSVQGDSENQVLVLVERRRTLYIQGERRLDFTGWLGAIQKAAASSGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVRLKEGEQHVDDVSSALKRFLRDLPDGLFTRVQRLSWLEASEIEDEEEKISRYRELLARLPPVNRATVKALISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTDGQDYKAGRVVEDLISRYVVVFSVDEEELRKQRDEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAEAEQHIKIPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSYLVVKKHQSMEAMLLYLASHVGETKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSHRPEKEWPVRSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCETQMELREWFATFLFMQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFAADPLSLLRNV", "length": 1200, "header": "tr|A0A5G2QQ18-1|A0A5G2QVJ5_PIG Computationally mapped isoform of Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Sus scrofa OX=9823 GN=ARAP1 PE=1 SV=3 CANONICAL=A0A5G2QVJ5-1" }, "locus": { "chromosome": "9", "start_pos": 7264231, "end_pos": 7238665, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085702.3", "url": "https://www.ensembl.org/id/ENSSSCT00000085702.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060382.3", "url": "https://www.ensembl.org/id/ENSSSCP00000060382.3" } ] } }, { "isoform_ac": "A0A5G2QVJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5/entry#A0A5G2QVJ5-1", "sequence": { "sequence": "MAEAGDAALSVAEWLRALHLEQYARLFEQHGLVWATECQGLSDARLVDMGVLLPGHRRRILAGLLRAHTPPAPAPRPAPRPVPMKRHVFRSPPVPAAPPEPLPTAGEDEGLPTAPPIPPRRSCIPPACFSTPSAAAPDPVLPPLPAKRHLPEQCVPPVPPRTGPPRPLVSLPTKEKELLLPPASSPPQPGPEEPPAVFPRGPPQPPTPPPSPPAIPPKPLRPLPEFDDSDYDEVPEEGPGAPAAVMTKKEERPASQVPRAVRVASLLSEGEELSGDDPGDEDEDDHAYEGVPNGGWHTSSLSSALPGSLLTPELPPPPMDGPPVSQDPSPVPPVIKAGWLDKNPPQGSYIYQKRWVRLDASYLQYFDSNKDAYSKRFVPVACISRVAAIGDQKFEVITNNRTFAFRAESDAERKEWIQALQQAVAEQRARARLSSAYPLGGGSEPPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEAADRRSFDLTTPYRIFSFSAESELEKEQWLEAMQGAIAEALSTSEVAERIWAVAPNRFCADCEAAQPDWASINLCVVICKRCAGAHRGLGAGVSKVRSLKMDRKVWTEVLIELFLQLGNAAGNHFWAANVPPSEALQPSSSPSARRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTSDLAETQALLGCGASVNCFSGDPGAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKPLQDRRAREEFSRRWCVLSDGVLSYYENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLENAELAREWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLTGSELHAVFPEGPCEEPLQLRKLQELSVQGDSENQVLVLVERRRTLYIQGERRLDFTGWLGAIQKAAASSGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVRLKEGEQHVDDVSSALKRFLRDLPDGLFTRVQRLSWLEASEIEDEEEKISRYRELLARLPPVNRATVKALISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTDGQDYKAGRVVEDLISRYVVVFSVDEEELRKQRDEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAEAEQHIKIPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSYLVVKKHQSMEAMLLYLASHVGETKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSQRPWSGAPETSHRPEKEWPVRSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCETQMELREWFATFLFMQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFAADPLSLLRNV", "length": 1456, "header": "tr|A0A5G2QVJ5-1|A0A5G2QVJ5_PIG Isoform 1 of Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Sus scrofa OX=9823 GN=ARAP1 PE=1 SV=3 CANONICAL=A0A5G2QVJ5-1" }, "locus": { "chromosome": "9", "start_pos": 7278248, "end_pos": 7238665, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068276.3", "url": "https://www.ensembl.org/id/ENSSSCT00000068276.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068888.3", "url": "https://www.ensembl.org/id/ENSSSCP00000068888.3" } ] } }, { "isoform_ac": "I3LPU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5/entry#I3LPU3-1", "sequence": { "sequence": "MAEAGDAALSVAEWLRALHLEQYARLFEQHGLVWATECQGLSDARLVDMGVLLPGHRRRILAGLLRAHTPPAPAPRPAPRPVPMKRHVFRSPPVPAAPPEPLPTAGEDEGLPTAPPIPPRRSCIPPACFSTPSAAAPDPVLPPLPAKRHLPEQCVPPVPPRTGPPRPLVSLPTKEKELLLPPASSPPQPGPEEPPAVFPRGPPQPPTPPPSPPAIPPKPLRPLPEFDDSDYDEVPEEGPGAPAAVMTKKEERPASQVPRAVRVASLLSEGEELSGDDPGDEDEDDHAYEGVPNGGWHTSSLSSALPGSLLTPELPPPPMDGPPVSQDPSPVPPVIKAGWLDKNPPQGSYIYQKRWVRLDASYLQYFDSNKDAYSKRFVPVACISRVAAIGDQKFEVITNNRTFAFRAESDAERKEWIQALQQAVAEQRARARLSSAYPLGGGSEPPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEAADRRSFDLTTPYRIFSFSAESELEKEQWLEAMQGAIAEALSTSEVAERIWAVAPNRFCADCEAAQPDWASINLCVVICKRCAGAHRGLGAGVSKVRSLKMDRKVWTEVLIELFLQLGNAAGNHFWAANVPPSEALQPSSSPSARRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTSDLAETQALLGCGASVNCFSGDPGAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKPLQDRRAREEFSRRWCVLSDGVLSYYENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLENAELAREWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLTGSELHAVFPEGPCEEPLQLRKLQELSVQGDSENQVLVLVERRRTLYIQGERRLDFTGWLGAIQKAAASSGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVRLKEGEQHVDDVSSALKRFLRDLPDGLFTRVQRLSWLEASEIEDEEEKISRYRELLARLPPVNRATVKALISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTDGQDYKAGRVVEDLISRYVVVFSVDEEELRKQRDEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAEAEQHIKIPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSYLVVKKHQSMEAMLLYLASHVGETKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSHRPEKEWPVRSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCETQMELREWFATFLFMQHDGLVWPSEPSRVSRAVPEVRLGSVSLIPLRGSENEMRRSVAAFAADPLSLLRNV", "length": 1445, "header": "tr|I3LPU3-1|A0A5G2QVJ5_PIG Computationally mapped isoform of Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Sus scrofa OX=9823 GN=ARAP1 PE=1 SV=5 CANONICAL=A0A5G2QVJ5-1" }, "locus": { "chromosome": "9", "start_pos": 7278248, "end_pos": 7238665, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025648.5", "url": "https://www.ensembl.org/id/ENSSSCT00000025648.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022964.5", "url": "https://www.ensembl.org/id/ENSSSCP00000022964.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 207, "start_aa": "Thr", "end_pos": 207, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr207", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ18" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8849469", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8849469", "resource": "Reactome", "description": "PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1" }, { "id": "R-SSC-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "podosome", "id": "GO:0002102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002102", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "extrinsic component of plasma membrane", "id": "GO:0019897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "regulation of bone resorption", "id": "GO:0045124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045124", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "regulation of cell projection organization", "id": "GO:0031344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031344", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "positive regulation of phagocytosis", "id": "GO:0050766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "positive regulation of filopodium assembly", "id": "GO:0051491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051491", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "regulation of receptor internalization", "id": "GO:0002090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002090", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "negative regulation of stress fiber assembly", "id": "GO:0051497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051497", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" }, { "name": "positive regulation of cellular component organization", "id": "GO:0051130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051130", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1313, "end_pos": 1315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 725, "end_pos": 727, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVJ5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1456, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVJ5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVJ5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" }, { "id": "PS50115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000259", "start_pos": 541, "end_pos": 666, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QVJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 333, "end_pos": 425, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QVJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 1178, "end_pos": 1267, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QVJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 964, "end_pos": 1145, "start_aa": "Asp", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QVJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ5" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 64, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 207 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1313, "end_pos": 1315 }, { "start_pos": 400, "end_pos": 402 }, { "start_pos": 725, "end_pos": 727 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQ25-1", "uniprot_ac": "A0A5G2QQ25", "uniprot_id": "A0A5G2QQ25_PIG", "mass": { "chemical_mass": 34951.0, "monoisotopic_mass": 34951.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ25/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ25#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ25" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ25", "locus": {} } ], "crossref": [ { "id": "A0A5G2QQ25", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ25", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000042791", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042791", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QQ25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ25-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LRYLTRNNVTEFILLGLTQNPHMQKVIFVVFLLIYAVSLGGNVLTIVTITTSPLIGCPMYYFLAHLSFIDACYSCVDTPKLVVDSLYEKKTSTFHGCMMQIFGEHFFAGADIILLTVMAYDRYVAICKPLYYATIMNRRLCGLLVGVSWLGGFLHGFIQILFIFRLPFCGPNVIDHFMCDLIPLLHLACTDTHTLGLVVAANSGFICLLIFLLLVGSYGVILNSLRKQCLEARRKALSTCVSHITAVVIFFVPCIFEYMRPAVTLPIDKAVAVFYTMITPMLNPLIYTLRNAQLKNAIRKLFSRKVISSEI", "length": 311, "header": "tr|A0A5G2QQ25-1|A0A5G2QQ25_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2QQ25-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQ25-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ25/entry#A0A5G2QQ25-1", "sequence": { "sequence": "LRYLTRNNVTEFILLGLTQNPHMQKVIFVVFLLIYAVSLGGNVLTIVTITTSPLIGCPMYYFLAHLSFIDACYSCVDTPKLVVDSLYEKKTSTFHGCMMQIFGEHFFAGADIILLTVMAYDRYVAICKPLYYATIMNRRLCGLLVGVSWLGGFLHGFIQILFIFRLPFCGPNVIDHFMCDLIPLLHLACTDTHTLGLVVAANSGFICLLIFLLLVGSYGVILNSLRKQCLEARRKALSTCVSHITAVVIFFVPCIFEYMRPAVTLPIDKAVAVFYTMITPMLNPLIYTLRNAQLKNAIRKLFSRKVISSEI", "length": 311, "header": "tr|A0A5G2QQ25-1|A0A5G2QQ25_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2QQ25-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 179875, "end_pos": 178658, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069943.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069943.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064169.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064169.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ25" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ25" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ25" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQ25-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQ25-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ25" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ25" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQ37-1", "uniprot_ac": "A0A5G2QQ37", "uniprot_id": "A0A5G2QQ37_PIG", "mass": { "chemical_mass": 34651.0, "monoisotopic_mass": 34651.0 }, "refseq": { "ac": "XP_020958301", "name": "olfactory receptor 502-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958301" }, "gene_names": [ { "name": "LOC110262259", "type": "synonym", "evidence": [ { "id": "XP_020958301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958301" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 502-like", "type": "synonym", "evidence": [ { "id": "XP_020958301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958301" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37", "locus": {} } ], "crossref": [ { "id": "A0A5G2QQ37", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ37", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050053", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050053", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15416", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15416", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110262259", "url": "https://www.ncbi.nlm.nih.gov/gene/110262259", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110262259", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110262259", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFIDIWY", "url": "https://omabrowser.org/oma/group/AFIDIWY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QQ37", "url": "https://www.orthodb.org/?gene=A0A5G2QQ37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020958301", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958301", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ37-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFLGKGNHTAVTEFMLLGLTNDPTLQTVLFVIILCIYLVTICGNLSTIILVRLSPQLHHPMYFFLSHLALADMGYSSSVTPSMLVNFLVERNTISYPGCAVQLGSCAFFGSTECFLLAAMAYDRFVAICNPLLYSTKMSTQVCVQLLIVSYMGGFLNAFAFTISFYSLLFCGPNRVNHFFCDVAPLLELSCSDVTIPAVVPSFIAGSIIVVTVVVIAISYIYILSTVLKMPSTEGRHKAFSTCTSHLTAVTLFYGTITFIYVMPKSSYSTDQNKVVSVFYMVVIPMLNPLIYSLRSKEIKGALKRQLGRKTFS", "length": 314, "header": "tr|A0A5G2QQ37-1|A0A5G2QQ37_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QQ37-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQ37-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37/entry#A0A5G2QQ37-1", "sequence": { "sequence": "MDFLGKGNHTAVTEFMLLGLTNDPTLQTVLFVIILCIYLVTICGNLSTIILVRLSPQLHHPMYFFLSHLALADMGYSSSVTPSMLVNFLVERNTISYPGCAVQLGSCAFFGSTECFLLAAMAYDRFVAICNPLLYSTKMSTQVCVQLLIVSYMGGFLNAFAFTISFYSLLFCGPNRVNHFFCDVAPLLELSCSDVTIPAVVPSFIAGSIIVVTVVVIAISYIYILSTVLKMPSTEGRHKAFSTCTSHLTAVTLFYGTITFIYVMPKSSYSTDQNKVVSVFYMVVIPMLNPLIYSLRSKEIKGALKRQLGRKTFS", "length": 314, "header": "tr|A0A5G2QQ37-1|A0A5G2QQ37_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QQ37-1" }, "locus": { "chromosome": "9", "start_pos": 1869510, "end_pos": 1868569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079455.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079455.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064184.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064184.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 81, "start_aa": "Thr", "end_pos": 81, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr81", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110262259", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110262259", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R6P4-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p76b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFLENGNYTALTEFILLGLTNDPVLRVILFIIILCIYLVTVSGNFSTILLIRVSSQLHHPMYFFLSHLAFADIGYSSSVTPNMLVNFLVERNTISYLGCGIQLGSAVFFGTVECLLLAAMAYDRFIAICSPLLYSNKMSTQVCVQLLIGSYIGGFLDASSFTLSFFSLLFCGPNRVNHFFCDFAPLVKLSCSDVSVPAVVPSFTAGSIIMMTMLVIAVSYIYILITILKMRSTEGRHKAFSTCTSHLTAVTLFYGTITFIYVMPKSSYSTDQNKVVSVFYMVVVPMLNPIIYSLRNKEIKGAMKRQFGKNTFS", "length": 314 }, "evidence": [ { "id": "A0A5G2QQ37", "url": "https://omabrowser.org/oma/group/A0A5G2QQ37/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQ37-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQ37-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ37" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ37" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 293, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 81 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQ62-1", "uniprot_ac": "A0A5G2QQ62", "uniprot_id": "A0A5G2QQ62_PIG", "mass": { "chemical_mass": 37109.0, "monoisotopic_mass": 37109.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100621857", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100621857", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62", "locus": {} } ], "crossref": [ { "id": "A0A5G2QQ62", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ62", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000048471", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000048471", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QQ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ILFQRPFIKDMGTKNATELTEFVLTGLTYPPAWQIPLVLLFLMLYLVTIMGNLGLITLIYNDPHLHIPMYLFLANLAFVDTWLSSTVTPKMLVNIITKDKMISLHECVVQFFSFGVSATTECFLLATMAYDRYVAICNPLLYPVIMTNKLCLRMLVSSFVGGLSHALIHTGFLLRLTFCNSNTIHHFYCDIMPLFKISCTNPSINVLMMFIFSGSIQVFTILIVLVSYTRILFTILKKRSAQGIRKAFSTCGAHLLSVSLYYGPLLFMYVRPGSAQADDQDAIDSLFYTVIIPFLNPIIYSLRNKKVKDSVRKVFEGKAISSSVHATVN", "length": 329, "header": "tr|A0A5G2QQ62-1|A0A5G2QQ62_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100621857 PE=3 SV=1 CANONICAL=A0A5G2QQ62-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62/entry#A0A5G2QQ62-1", "sequence": { "sequence": "ILFQRPFIKDMGTKNATELTEFVLTGLTYPPAWQIPLVLLFLMLYLVTIMGNLGLITLIYNDPHLHIPMYLFLANLAFVDTWLSSTVTPKMLVNIITKDKMISLHECVVQFFSFGVSATTECFLLATMAYDRYVAICNPLLYPVIMTNKLCLRMLVSSFVGGLSHALIHTGFLLRLTFCNSNTIHHFYCDIMPLFKISCTNPSINVLMMFIFSGSIQVFTILIVLVSYTRILFTILKKRSAQGIRKAFSTCGAHLLSVSLYYGPLLFMYVRPGSAQADDQDAIDSLFYTVIIPFLNPIIYSLRNKKVKDSVRKVFEGKAISSSVHATVN", "length": 329, "header": "tr|A0A5G2QQ62-1|A0A5G2QQ62_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100621857 PE=3 SV=1 CANONICAL=A0A5G2QQ62-1" }, "locus": { "chromosome": "13", "start_pos": 161163145, "end_pos": 161161968, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089772.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089772.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066862.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066862.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQ62-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 329, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQ62-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ62" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ62" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 300, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQ87-1", "uniprot_ac": "A0A5G2QQ87", "uniprot_id": "A0A5G2QQ87_PIG", "mass": { "chemical_mass": 35787.0, "monoisotopic_mass": 35787.0 }, "refseq": { "ac": "XP_020958310", "name": "olfactory receptor 52N2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958310" }, "gene_names": [ { "name": "LOC110262260", "type": "synonym", "evidence": [ { "id": "XP_020958310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958310" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 52N2-like", "type": "synonym", "evidence": [ { "id": "XP_020958310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958310" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ87", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ87", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ87", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87", "locus": {} } ], "crossref": [ { "id": "A0A5G2QQ87", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ87", "database": "AlphaFoldDB", "categories": [] }, { "id": "110262260", "url": "https://www.ncbi.nlm.nih.gov/gene/110262260", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110262260", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110262260", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EINFSIC", "url": "https://omabrowser.org/oma/group/EINFSIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QQ87", "url": "https://www.orthodb.org/?gene=A0A5G2QQ87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020958310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958310", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ87", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ87-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHGANSSSLTPTHFILSGIPGLEAAHVWISLPFCFMYVIAVTGNCGLMYIISHEEALHRPMYYFLALLSLIDISGCTSFVPNTLCIFWLHLKEIDFNACLVQMFFIHMLTGMESGVLMLMALDRYVAICYPLRYATILTNTTIAKVGLATLMRSVLLVIPFTFLIKRLPYCRGNLVQHTYCDHMSLAKLSCGNIKINAVYGLIAALLNGGSDIICISLSYTMIIRAVINLASADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGRSIPHHVHILIANLYLLLPPTLNPIVYGVKTKQIREGVIKLFTREKDAFRVR", "length": 320, "header": "tr|A0A5G2QQ87-1|A0A5G2QQ87_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QQ87-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQ87-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87/entry#A0A5G2QQ87-1", "sequence": { "sequence": "MHGANSSSLTPTHFILSGIPGLEAAHVWISLPFCFMYVIAVTGNCGLMYIISHEEALHRPMYYFLALLSLIDISGCTSFVPNTLCIFWLHLKEIDFNACLVQMFFIHMLTGMESGVLMLMALDRYVAICYPLRYATILTNTTIAKVGLATLMRSVLLVIPFTFLIKRLPYCRGNLVQHTYCDHMSLAKLSCGNIKINAVYGLIAALLNGGSDIICISLSYTMIIRAVINLASADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGRSIPHHVHILIANLYLLLPPTLNPIVYGVKTKQIREGVIKLFTREKDAFRVR", "length": 320, "header": "tr|A0A5G2QQ87-1|A0A5G2QQ87_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QQ87-1" }, "locus": { "chromosome": "9", "start_pos": 3664160, "end_pos": 3663201, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085630.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085630.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060448.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060448.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ87", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110262260", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110262260", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ87", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ87", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ87", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQ87-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQ87-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ87" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQ87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ87" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 295, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQ88-1", "uniprot_ac": "A0A5G2QQ88", "uniprot_id": "A0A5G2QQ88_PIG", "mass": { "chemical_mass": 34688.0, "monoisotopic_mass": 34688.0 }, "refseq": { "ac": "XP_013845984", "name": "olfactory receptor 7G2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845984" }, "gene_names": [ { "name": "LOC100624207", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88" } ] }, { "name": "LOC100624207", "type": "synonym", "evidence": [ { "id": "XP_013845984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845984" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7G2-like", "type": "synonym", "evidence": [ { "id": "XP_013845984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845984" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100624207", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88", "locus": {} } ], "crossref": [ { "id": "A0A5G2QQ88", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ88", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100624207", "url": "https://www.ncbi.nlm.nih.gov/gene/100624207", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624207", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624207", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHPLVYM", "url": "https://omabrowser.org/oma/group/CHPLVYM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QQ88", "url": "https://www.orthodb.org/?gene=A0A5G2QQ88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013845984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845984", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ88-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSRNQTDVSKFLLLGLTEDPELQPFLFFLFLSIYLVTVLGNLLIILAVSSDSHLHTPMYFFLSSLSFIDICISTTTIPKMLVNIQAQIQHITYTGCLTQIGFVLIFGGLENFILAAMAYDRYVAICHPLRYMVIVNPQLCVLLILLSLLISTMVALILSLTMLRLSFCKNLEIPHFFCELAQVIKLACSDTLINNILIYLAIGVFGAISLPGIIFSYIRIVSSVLRMPSARAKLKAFSTCGSHLSVVSLFYGTVFGVYISSEVTTSPRKTSVASVMYIVVPQMMNPFIYSLRNSDMKGALRKLINGITSFL", "length": 312, "header": "tr|A0A5G2QQ88-1|A0A5G2QQ88_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100624207 PE=3 SV=1 CANONICAL=A0A5G2QQ88-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQ88-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88/entry#A0A5G2QQ88-1", "sequence": { "sequence": "MNSRNQTDVSKFLLLGLTEDPELQPFLFFLFLSIYLVTVLGNLLIILAVSSDSHLHTPMYFFLSSLSFIDICISTTTIPKMLVNIQAQIQHITYTGCLTQIGFVLIFGGLENFILAAMAYDRYVAICHPLRYMVIVNPQLCVLLILLSLLISTMVALILSLTMLRLSFCKNLEIPHFFCELAQVIKLACSDTLINNILIYLAIGVFGAISLPGIIFSYIRIVSSVLRMPSARAKLKAFSTCGSHLSVVSLFYGTVFGVYISSEVTTSPRKTSVASVMYIVVPQMMNPFIYSLRNSDMKGALRKLINGITSFL", "length": 312, "header": "tr|A0A5G2QQ88-1|A0A5G2QQ88_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100624207 PE=3 SV=1 CANONICAL=A0A5G2QQ88-1" }, "locus": { "chromosome": "2", "start_pos": 67136452, "end_pos": 67135517, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081164.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081164.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066892.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066892.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624207", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624207", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q7TRG4-1", "protein_name": "Olfactory receptor", "gene_name": "Or7g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEISNQSGISEFFLTGLTYSPAIESFIFSLFLSIYFVTIFGNILIILAVRLDYHLHTPMYFFIANLSFTDICISTTIIPKMLLNIETQNQSITYTGCLSQVCFVLIFGGLESCLLAVMAYDRYLAIVHPLRYTVIMNPCLCVLLVLLSLFISTINALLHSLMLLKLSFCKDQNILHFFCELVQVIKHACSDTFINTLLIYTVTSVFAGFPLAGIIFSYIQIVSSILKISSVQGRNKAFSTCGSHLSVVSLFYGTAFGVYMSSAVSDSSVKNIVFSMMYTVVPQMLNPFIYSLRNREMKQAMRHLLFPVVLSSP", "length": 313 }, "evidence": [ { "id": "A0A5G2QQ88", "url": "https://omabrowser.org/oma/group/A0A5G2QQ88/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQ88-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQ88-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ88" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQ88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ88" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQ91-1", "uniprot_ac": "A0A5G2QQ91", "uniprot_id": "A0A5G2QQ91_PIG", "mass": { "chemical_mass": 34752.0, "monoisotopic_mass": 34752.0 }, "refseq": {}, "gene_names": [ { "name": "OR10J4", "type": "recommended", "evidence": [ { "id": "A0A5G2QQ91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 10 subfamily J member 4/pseudo", "type": "synonym", "evidence": [ { "id": "A0A5G2QQ91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ91", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ91", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OR10J4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91", "locus": { "chromosome": "4", "start_pos": 91024840, "end_pos": 91025775, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000029064", "url": "https://www.ensembl.org/id/ENSSSCG00000029064" } ] } } ], "crossref": [ { "id": "A0A5G2QQ91", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ91", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000029064", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000029064", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QQ91", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ91-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRSNFTAVAEFTFEGFSIFGWQHRLILFVVFLALYLLTLASNVIILTVIHLNRQLHTPMYFFLSVLSISETCYTVAIIPRMLASLLSPQQAISAPECATQLFFYLTFGVNNCFLLTAMGYDRYVAICNPLRYSVIMGKKTCIQLASGSWSIGLSTAIIQVSSVFSLPFCDANIISHFFCDIRPLMKLACADTTIKELITLLISLCVLVLPMVLIFISYVLIVTTILKMASAEGRKKAFATCASHLTVVIVHYGCTSFIYLKPKSQNSLQDRLISVTYTVITPLLNPVVYSLRNKEVKEAFLRALGRKLLS", "length": 311, "header": "tr|A0A5G2QQ91-1|A0A5G2QQ91_PIG Isoform 1 of Olfactory receptor family 10 subfamily J member 4/pseudo OS=Sus scrofa OX=9823 GN=OR10J4 PE=3 SV=1 CANONICAL=A0A5G2QQ91-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQ91-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91/entry#A0A5G2QQ91-1", "sequence": { "sequence": "MTRSNFTAVAEFTFEGFSIFGWQHRLILFVVFLALYLLTLASNVIILTVIHLNRQLHTPMYFFLSVLSISETCYTVAIIPRMLASLLSPQQAISAPECATQLFFYLTFGVNNCFLLTAMGYDRYVAICNPLRYSVIMGKKTCIQLASGSWSIGLSTAIIQVSSVFSLPFCDANIISHFFCDIRPLMKLACADTTIKELITLLISLCVLVLPMVLIFISYVLIVTTILKMASAEGRKKAFATCASHLTVVIVHYGCTSFIYLKPKSQNSLQDRLISVTYTVITPLLNPVVYSLRNKEVKEAFLRALGRKLLS", "length": 311, "header": "tr|A0A5G2QQ91-1|A0A5G2QQ91_PIG Isoform 1 of Olfactory receptor family 10 subfamily J member 4/pseudo OS=Sus scrofa OX=9823 GN=OR10J4 PE=3 SV=1 CANONICAL=A0A5G2QQ91-1" }, "locus": { "chromosome": "4", "start_pos": 91025775, "end_pos": 91024843, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030893.3", "url": "https://www.ensembl.org/id/ENSSSCT00000030893.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064234.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064234.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ91", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ91", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ91", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ91", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ91", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ91", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ91", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQ91-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQ91-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQ91" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQ91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ91" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 290, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQB4-1", "uniprot_ac": "A0A5G2QQB4", "uniprot_id": "A0A5G2QQB4_PIG", "mass": { "chemical_mass": 51392.0, "monoisotopic_mass": 51392.0 }, "refseq": {}, "gene_names": [ { "name": "PAH", "type": "recommended", "evidence": [ { "id": "A0A5G2QQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4" } ] } ], "protein_names": [ { "name": "Phenylalanine-4-hydroxylase", "type": "recommended", "evidence": [ { "id": "A0A5G2QQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4/entry#names_and_taxonomy" } ] }, { "name": "1.14.16.1", "type": "synonym", "evidence": [ { "id": "A0A5G2QQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4/entry#names_and_taxonomy" } ] }, { "name": "Phe-4-monooxygenase", "type": "synonym", "evidence": [ { "id": "A0A5G2QQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine.", "evidence": [ { "database": "UniProtKB", "id": "F1SRJ8", "url": "https://www.uniprot.org/uniprotkb/F1SRJ8#function" }, { "database": "UniProtKB", "id": "ARBA00058511", "url": "https://www.uniprot.org/uniprotkb/ARBA00058511#function" }, { "database": "UniProtKB", "id": "I3L5I9", "url": "https://www.uniprot.org/uniprotkb/I3L5I9#function" }, { "database": "UniProtKB", "id": "A0A5G2QQB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PAH", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4", "locus": { "chromosome": "5", "start_pos": 81463451, "end_pos": 81385435, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000856", "url": "https://www.ensembl.org/id/ENSSSCG00000000856" } ] } } ], "crossref": [ { "id": "A0A5G2QQB4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQB4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000856", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000856", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03347", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03347", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04931", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04931", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11473", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11473", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11473:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11473:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00351", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00351", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01842", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01842", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8964208", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964208", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "20273", "url": "https://www.rhea-db.org/rhea/20273", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QQB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SRJ8", "url": "https://www.uniprot.org/uniprotkb/F1SRJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SRJ8-1", "url": "https://www.uniprot.org/uniprotkb/F1SRJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L5I9", "url": "https://www.uniprot.org/uniprotkb/I3L5I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L5I9-1", "url": "https://www.uniprot.org/uniprotkb/I3L5I9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAAVLENGGGGRKLSDWGQETSYIEDSSSQDGSISLIFSLKEEVGALAKVLRLFEENGINLTHIESRPSRLKKDEYEFFTHLDKGSMPTLSDIIKILRHDIGATVHELSRDKKKDTVPWFPKTIQELDRFANQILSYGAELDADHPGFKDPVYRTRRKYFADIAYNYRHGQPIPRVEYTEEEKKTWGTVFKNLKSLYQTHACYEYNHIFPLLEKYCGFCEDNIPQLEEVSQFLQSCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHASKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASGAPDEYIEKLATIYWFTVEFGLCKQEDSIKAYGAGLLSSFGELQYCLSGEPKLLTLELEKTAVQEYTVTEFQLYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINGEVGILCNALQKLK", "length": 450, "header": "tr|A0A5G2QQB4-1|A0A5G2QQB4_PIG Isoform 1 of Phenylalanine-4-hydroxylase OS=Sus scrofa OX=9823 GN=PAH PE=1 SV=1 CANONICAL=A0A5G2QQB4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4/entry#A0A5G2QQB4-1", "sequence": { "sequence": "MSAAVLENGGGGRKLSDWGQETSYIEDSSSQDGSISLIFSLKEEVGALAKVLRLFEENGINLTHIESRPSRLKKDEYEFFTHLDKGSMPTLSDIIKILRHDIGATVHELSRDKKKDTVPWFPKTIQELDRFANQILSYGAELDADHPGFKDPVYRTRRKYFADIAYNYRHGQPIPRVEYTEEEKKTWGTVFKNLKSLYQTHACYEYNHIFPLLEKYCGFCEDNIPQLEEVSQFLQSCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHASKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASGAPDEYIEKLATIYWFTVEFGLCKQEDSIKAYGAGLLSSFGELQYCLSGEPKLLTLELEKTAVQEYTVTEFQLYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINGEVGILCNALQKLK", "length": 450, "header": "tr|A0A5G2QQB4-1|A0A5G2QQB4_PIG Isoform 1 of Phenylalanine-4-hydroxylase OS=Sus scrofa OX=9823 GN=PAH PE=1 SV=1 CANONICAL=A0A5G2QQB4-1" }, "locus": { "chromosome": "5", "start_pos": 81459984, "end_pos": 81385602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074350.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074350.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060473.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060473.1" } ] } }, { "isoform_ac": "F1SRJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4/entry#F1SRJ8-1", "sequence": { "sequence": "MSAAVLENGGGGRKLSDWGQETSYIEDSSSQDGSISLIFSLKEEVGALAKVLRLFEENGINLTHIESRPSRLKKDEYEFFTHLDKGSMPTLSDIIKILRHDIGATVHELSRDKKKDTVPWFPKTIQELDRFANQILSYGAELDADHPGFKDPVYRTRRKYFADIAYNYRHGQPIPRVEYTEEEKKTWGTVFKNLKSLYQTHACYEYNHIFPLLEKYCGFCEDNIPQLEEVSQFLQSCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHASKPMYTPEPDICHELLGHVPLFSDRSFAQFSQYIEKLATIYWFTVEFGLCKQEDSIKAYGAGLLSSFGELQYCLSGEPKLLTLELEKTAVQEYTVTDFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINGK", "length": 418, "header": "tr|F1SRJ8-1|F1SRJ8_PIG Computationally mapped isoform of Phenylalanine-4-hydroxylase OS=Sus scrofa OX=9823 GN=PAH PE=1 SV=4 CANONICAL=A0A5G2QQB4-1" }, "locus": { "chromosome": "5", "start_pos": 81453787, "end_pos": 81385602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000934.5", "url": "https://www.ensembl.org/id/ENSSSCT00000000934.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000914.4", "url": "https://www.ensembl.org/id/ENSSSCP00000000914.4" } ] } }, { "isoform_ac": "I3L5I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4/entry#I3L5I9-1", "sequence": { "sequence": "MSAAVLENGGGGRKLSDWGQETSYIEDSSSQDGSISLIFSLKEEVGALAKVLRLFEENGINLTHIESRPSRLKKDEYEFFTHLDKGSMPTLSDIIKILRHDIGATVHELSRDKKKDTVPWFPKTIQELDRFANQILSYGAELDADHPGFKDPVYRTRRKYFADIAYNYRHGQPIPRVEYTEEEKKTWGTVFKNLKSLYQTHACYEYNHIFPLLEKYCGFCEDNIPQLEEVSQFLQSCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHASKPMYTPEPDICHELLGHVPLFSDRSFAQFSQYIEKLATIYWFTVEFGLCKQEDSIKAYGAGLLSSFGELQEPRMNSKAVVPALYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINGK", "length": 411, "header": "tr|I3L5I9-1|I3L5I9_PIG Computationally mapped isoform of Phenylalanine-4-hydroxylase OS=Sus scrofa OX=9823 GN=PAH PE=1 SV=3 CANONICAL=A0A5G2QQB4-1" }, "locus": { "chromosome": "5", "start_pos": 81453787, "end_pos": 81385602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022294.4", "url": "https://www.ensembl.org/id/ENSSSCT00000022294.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019288.3", "url": "https://www.ensembl.org/id/ENSSSCP00000019288.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8964208", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964208", "resource": "Reactome", "description": "Phenylalanine metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tyrosine biosynthetic process", "id": "GO:0006571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006571", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4" } ], "pmid": "" }, { "name": "L-phenylalanine catabolic process", "id": "GO:0006559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006559", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4" } ], "pmid": "" }, { "name": "phenylalanine 4-monooxygenase activity", "id": "GO:0004505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004505", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20273", "name": "", "equation": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20273", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20273" } ] }, { "id": "R-SSC-71118", "name": "PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-71118", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71118" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQB4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 450, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQB4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQB4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4" }, { "id": "PS51671", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51671" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ACT", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 114, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4" }, { "id": "PS51410", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51410" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Biopterin-dependent aromatic amino acid hydroxylase family profile", "eco_id": "ECO_0000259", "start_pos": 106, "end_pos": 450, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A5G2QQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4#function" }, { "id": "A0A5G2QQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" }, { "id": "F1SRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1SRJ8#function" }, { "id": "F1SRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1SRJ8" }, { "id": "I3L5I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3L5I9#function" }, { "id": "I3L5I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3L5I9" } ], "binding_site_uniprot": 285, "amino_acid": "His", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 285, "end_pos": 285, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4#function" }, { "id": "A0A5G2QQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" }, { "id": "F1SRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1SRJ8#function" }, { "id": "F1SRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1SRJ8" }, { "id": "I3L5I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3L5I9#function" }, { "id": "I3L5I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3L5I9" } ], "binding_site_uniprot": 290, "amino_acid": "His", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 290, "end_pos": 290, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1SRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1SRJ8#function" }, { "id": "F1SRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1SRJ8" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" }, { "id": "I3L5I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3L5I9#function" }, { "id": "I3L5I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3L5I9" } ], "binding_site_uniprot": 318, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 318, "end_pos": 318, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4#function" }, { "id": "A0A5G2QQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQB4" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" } ], "binding_site_uniprot": 329, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 329, "end_pos": 329, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQH8-1", "uniprot_ac": "A0A5G2QQH8", "uniprot_id": "A0A5G2QQH8_PIG", "mass": { "chemical_mass": 34551.0, "monoisotopic_mass": 34551.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "LINE-1 type transposase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2QQH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QQH8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050436", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050436", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QQH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLRNHSQSNQQENSPKTVNNETDLGSLTDLEFKREIVKILKELREDMNSNADTLRKDLENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNIQPRILYPARISFKIEGEMKIFPNKQKLKEYSNTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2QQH8-1|A0A5G2QQH8_PIG Isoform 1 of LINE-1 type transposase domain-containing protein 1 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QQH8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8/entry#A0A5G2QQH8-1", "sequence": { "sequence": "MKKLRNHSQSNQQENSPKTVNNETDLGSLTDLEFKREIVKILKELREDMNSNADTLRKDLENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNIQPRILYPARISFKIEGEMKIFPNKQKLKEYSNTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2QQH8-1|A0A5G2QQH8_PIG Isoform 1 of LINE-1 type transposase domain-containing protein 1 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QQH8-1" }, "locus": { "chromosome": "6", "start_pos": 46420044, "end_pos": 46419157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084301.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084301.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060533.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060533.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQH8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 296, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQH8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQH8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 227, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QQH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8" }, { "id": "PF17490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element dsRBD-like", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 293, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QQH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH8" }, { "id": "PF17489", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element trimerization", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 128, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 22, "end_pos": 24 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQI8-1", "uniprot_ac": "A0A5G2QQI8", "uniprot_id": "A0A5G2QQI8_PIG", "mass": { "chemical_mass": 34703.0, "monoisotopic_mass": 34703.0 }, "refseq": { "ac": "XP_020938022", "name": "olfactory receptor 4C46-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938022" }, "gene_names": [ { "name": "LOC110259070", "type": "recommended", "evidence": [ { "id": "A0A5G2QQI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8" } ] }, { "name": "LOC110259070", "type": "synonym", "evidence": [ { "id": "XP_020938022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938022" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QQI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4C46-like", "type": "synonym", "evidence": [ { "id": "XP_020938022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938022" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259070", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QQI8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQI8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110259070", "url": "https://www.ncbi.nlm.nih.gov/gene/110259070", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110259070", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259070", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVNTPKV", "url": "https://omabrowser.org/oma/group/CVNTPKV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QQI8", "url": "https://www.orthodb.org/?gene=A0A5G2QQI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020938022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QQI8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METRNNVTEFILLGLTQNPQMQKVIFIVFLIVYMVSMVGNVLTVVTITLSPLLKSPMYYFLAHLSFIDACYSCVNTPKLIVDSLYEKKTSLFNACMTQIFGEHFFGGADVILLTVMAYDRYVAICKPLYYATIMNRQLCGLLVGVVWVGGFLHGFIQILFIFRLPFCGPNVIDHFMCDLNPLLDLACTDTHTLGLFVAANSGFICLLNFLLLMGSYVVILNSLRTQSLEARQKALSTCVSHITAVILFFVPCIFVYMRPAATLPIDKAVAVFYTMITPMLNPLIYTLRNAQMKNAIRKLCSRKLISGEI", "length": 309, "header": "tr|A0A5G2QQI8-1|A0A5G2QQI8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259070 PE=3 SV=1 CANONICAL=A0A5G2QQI8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8/entry#A0A5G2QQI8-1", "sequence": { "sequence": "METRNNVTEFILLGLTQNPQMQKVIFIVFLIVYMVSMVGNVLTVVTITLSPLLKSPMYYFLAHLSFIDACYSCVNTPKLIVDSLYEKKTSLFNACMTQIFGEHFFGGADVILLTVMAYDRYVAICKPLYYATIMNRQLCGLLVGVVWVGGFLHGFIQILFIFRLPFCGPNVIDHFMCDLNPLLDLACTDTHTLGLFVAANSGFICLLNFLLLMGSYVVILNSLRTQSLEARQKALSTCVSHITAVILFFVPCIFVYMRPAATLPIDKAVAVFYTMITPMLNPLIYTLRNAQMKNAIRKLCSRKLISGEI", "length": 309, "header": "tr|A0A5G2QQI8-1|A0A5G2QQI8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259070 PE=3 SV=1 CANONICAL=A0A5G2QQI8-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 213363, "end_pos": 212437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074852.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074852.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066997.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066997.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110259070", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259070", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BQ36-1", "protein_name": "Olfactory receptor", "gene_name": "OR4C175", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDNANNVTEFILLGLSQNPKMQKIIFVVFLVVYIVSMVGNVFTMVTIITSPLLGYPMYYFLAHLSFIDACYSCVSTPKVIIDSFYEKKTSPFNECMTQVFGEHIFGGADVILLTVMAYDRYVAICKPLHYTTIMNRRLCGLLVGVAWVGGIIHSTIQLLFIISLPFCGPNVIDHFMCDLNPLLYLACTDTHILGFFVPANTGLICLSNFLLLIGSYVIILRSLRAHSLQARRKALSTCVSHITAVILFLVPCLFVYLRPTVTLPVDKAVSVFYTMITPMLNPLIYTLRNDQMKSAIRKLCSRKVISGDA", "length": 309 }, "evidence": [ { "id": "A0A5G2QQI8", "url": "https://omabrowser.org/oma/group/A0A5G2QQI8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQI8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQI8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQI8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQI8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQK4-1", "uniprot_ac": "A0A5G2QQK4", "uniprot_id": "A0A5G2QQK4_PIG", "mass": { "chemical_mass": 35299.0, "monoisotopic_mass": 35299.0 }, "refseq": { "ac": "XP_001927864", "name": "olfactory receptor 4F6-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927864" }, "gene_names": [ { "name": "LOC100155519", "type": "recommended", "evidence": [ { "id": "A0A5G2QQK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4" } ] }, { "name": "LOC100155519", "type": "synonym", "evidence": [ { "id": "XP_001927864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927864" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QQK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4F6-like", "type": "synonym", "evidence": [ { "id": "XP_001927864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927864" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100155519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4", "locus": {} } ], "crossref": [ { "id": "A0A5G2QQK4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155519", "url": "https://www.ncbi.nlm.nih.gov/gene/100155519", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155519", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155519", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HSMTQLA", "url": "https://omabrowser.org/oma/group/HSMTQLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QQK4", "url": "https://www.orthodb.org/?gene=A0A5G2QQK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001927864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927864", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QQK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEANHSVVSEFVFLGLSDSWEIQLLLFLFSSVFYVASLMGNLLIVFSVTSDPRLHSPMYFLLANLSIIDLIFCSSTVPKMIYDLLRKDKTISFGGCVVQIFFIHAVGGTKMVLLISMAYDRYVAICKPLHYLSIMNPRRCILFLVTSWIIGLIHSVTQLAFVVDLPFCGPNELDSFFCDLPRFTKLACIETYTLGFMVTANSGFISVASFLILIISYIFIFVTVWKRSSGGVSKAFSTLSAHVTVVVLFFGPLIFFYMWPFPISHVDKFLAIFDAVITPFLNPIIYTLRNKEMKVAMRRLCTQFVNDSKIS", "length": 312, "header": "tr|A0A5G2QQK4-1|A0A5G2QQK4_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100155519 PE=3 SV=1 CANONICAL=A0A5G2QQK4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4/entry#A0A5G2QQK4-1", "sequence": { "sequence": "MDEANHSVVSEFVFLGLSDSWEIQLLLFLFSSVFYVASLMGNLLIVFSVTSDPRLHSPMYFLLANLSIIDLIFCSSTVPKMIYDLLRKDKTISFGGCVVQIFFIHAVGGTKMVLLISMAYDRYVAICKPLHYLSIMNPRRCILFLVTSWIIGLIHSVTQLAFVVDLPFCGPNELDSFFCDLPRFTKLACIETYTLGFMVTANSGFISVASFLILIISYIFIFVTVWKRSSGGVSKAFSTLSAHVTVVVLFFGPLIFFYMWPFPISHVDKFLAIFDAVITPFLNPIIYTLRNKEMKVAMRRLCTQFVNDSKIS", "length": 312, "header": "tr|A0A5G2QQK4-1|A0A5G2QQK4_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100155519 PE=3 SV=1 CANONICAL=A0A5G2QQK4-1" }, "locus": { "chromosome": "AEMK02000131.1", "start_pos": 69938, "end_pos": 69003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072658.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072658.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067187.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067187.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155519", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155519", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQK4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQK4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQK4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQK4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 307, "end_pos": 309 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QTD5-1", "uniprot_ac": "A0A5G2QTD5", "uniprot_id": "A0A5G2QTD5_PIG", "mass": { "chemical_mass": 69861.0, "monoisotopic_mass": 69861.0 }, "refseq": { "ac": "XP_020950573", "name": "cationic amino acid transporter 3-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950573" }, "gene_names": [ { "name": "LOC110255287", "type": "recommended", "evidence": [ { "id": "A0A5G2QTD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5" } ] }, { "name": "LOC110255287", "type": "synonym", "evidence": [ { "id": "XP_020950573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950573" } ] } ], "protein_names": [ { "name": "Cationic amino acid transporter C-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QTD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5/entry#names_and_taxonomy" } ] }, { "name": "cationic amino acid transporter 3-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020950573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950573" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110255287", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5", "locus": {} } ], "crossref": [ { "id": "A0A5G2QTD5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000038825", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000038825", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110255287", "url": "https://www.ncbi.nlm.nih.gov/gene/110255287", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002293", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002293", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110255287", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255287", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QTD5", "url": "https://www.orthodb.org/?gene=A0A5G2QTD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43243:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43243:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020950573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QQY8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTHAAPCVYLTDVLLSKIGAASTMSGMLGQRVGQFGEKLVRKRPLEPREESEIPTLHPNILNLVLFGVNTPKARIYILAGAMAVSVAGPAIIISFLVFGLFSLLSGFFFGELVARVPRSGSVYLYSYVTMGQLHAFITGWNLILHLGIATACVTRAWSYTFDSLIGNHISQVLEGTFSEHVPSFLSPYPDIVALVLVLVMTGLLILGVHDSALVSKVSEGVNVLVLSFMILSGFIKGDLHNWQLTEQDYKLAASGSNDTSSLGPLGSGGFVPFGFEGILRGAAMPFYSYFGLNAIITTGRETPNPQRSIPWSIGIIISICFLAYSGVSAALTLMVPYYQIHPYNPLPQAFHHVGWAPAGYFVAVVILCALFYSLLLVMLTMSQLICAMAEDGLLFQGLGQIYARRGTPLVAVLVSAILSGILAVLFEIFHLVELLSVGALFVYFLVTFSVLVLRYQPDQSFSKKEKVEEEIEMEPIVEGNPSPSVPEAGTSNPLKSLCNPISTTPTLKSGQIVYGCAFLLVLLLTILSLLLALWPSRVFSGDPGFTAGAVLLLLLIAGITAIIWRQPQNPSPLPFRVPALPVLPVLSIFVNVYLMMQMSSVTWAQCGIWNALGLATYFGYGIRHSPEGKRDPQPPASSLQLPDPS", "length": 646, "header": "tr|A0A5G2QTD5-1|A0A5G2QTD5_PIG Isoform 1 of Cationic amino acid transporter C-terminal domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110255287 PE=3 SV=1 CANONICAL=A0A5G2QTD5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5/entry#A0A5G2QQY8-1", "sequence": { "sequence": "MSGMLGQRVGQFGEKLVRKRPLEPREESEIPTLHPNILNLVLFGVNTPKARIYILAGAMAVSVAGPAIIISFLVFGLFSLLSGFFFGELVARVPRSGSVYLYSYVTMGQLHAFITGWNLILHLGIATACVTRAWSYTFDSLIGNHISQVLEGTFSEHVPSFLSPYPDIVALVLVLVMTGLLILGVHDSALVSKVSEGVNVLVLSFMILSGFIKGDLHNWQLTEQDYKLAASGSNDTSSLGPLGSGGFVPFGFEGILRGAAMPFYSYFGLNAIITTGRETPNPQRSIPWSIGIIISICFLAYSGVSAALTLMVPYYQIHPYNPLPQAFHHVGWAPAGYFVAVVILCALFYSLLLVMLTMSQLICAMAEDGLLFQGLGQIYARRGTPLVAVLVSAILSGILAVLFEIFHLVELLSVGALFVYFLVTFSVLVLRYQPDQSFSKKEKVEEEIEMEPIVEGNPSPSVPEAGTSNPLKSLCNPISTTPTLKSGQIVYGCAFLLVLLLTILSLLLALWPSRVFSGDPGFTAGAVLLLLLIAGITAIIWRQPQNPSPLPFRVPALPVLPVLSIFVNVYLMMQMSSVTWAQCGIWNALGLATYFGYGIRHSPEGKRDPQPPASSLQLPDPS", "length": 622, "header": "tr|A0A5G2QQY8-1|A0A5G2QTD5_PIG Computationally mapped isoform of Cationic amino acid transporter C-terminal domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110255287 PE=3 SV=1 CANONICAL=A0A5G2QTD5-1" }, "locus": { "chromosome": "6", "start_pos": 56506677, "end_pos": 56501564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074354.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074354.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060694.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060694.1" } ] } }, { "isoform_ac": "A0A5G2QTD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5/entry#A0A5G2QTD5-1", "sequence": { "sequence": "MLTHAAPCVYLTDVLLSKIGAASTMSGMLGQRVGQFGEKLVRKRPLEPREESEIPTLHPNILNLVLFGVNTPKARIYILAGAMAVSVAGPAIIISFLVFGLFSLLSGFFFGELVARVPRSGSVYLYSYVTMGQLHAFITGWNLILHLGIATACVTRAWSYTFDSLIGNHISQVLEGTFSEHVPSFLSPYPDIVALVLVLVMTGLLILGVHDSALVSKVSEGVNVLVLSFMILSGFIKGDLHNWQLTEQDYKLAASGSNDTSSLGPLGSGGFVPFGFEGILRGAAMPFYSYFGLNAIITTGRETPNPQRSIPWSIGIIISICFLAYSGVSAALTLMVPYYQIHPYNPLPQAFHHVGWAPAGYFVAVVILCALFYSLLLVMLTMSQLICAMAEDGLLFQGLGQIYARRGTPLVAVLVSAILSGILAVLFEIFHLVELLSVGALFVYFLVTFSVLVLRYQPDQSFSKKEKVEEEIEMEPIVEGNPSPSVPEAGTSNPLKSLCNPISTTPTLKSGQIVYGCAFLLVLLLTILSLLLALWPSRVFSGDPGFTAGAVLLLLLIAGITAIIWRQPQNPSPLPFRVPALPVLPVLSIFVNVYLMMQMSSVTWAQCGIWNALGLATYFGYGIRHSPEGKRDPQPPASSLQLPDPS", "length": 646, "header": "tr|A0A5G2QTD5-1|A0A5G2QTD5_PIG Isoform 1 of Cationic amino acid transporter C-terminal domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110255287 PE=3 SV=1 CANONICAL=A0A5G2QTD5-1" }, "locus": { "chromosome": "6", "start_pos": 56506677, "end_pos": 56496039, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070484.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070484.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065259.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065259.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 130, "start_aa": "Thr", "end_pos": 130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr130", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQY8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQY8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110255287", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255287", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5" } ], "pmid": "" }, { "name": "amino acid transmembrane transporter activity", "id": "GO:0015171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QTD5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 646, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QTD5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTD5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QTD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTD5" }, { "id": "PF13906", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13906" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cationic amino acid transporter C-terminal", "eco_id": "ECO_0000259", "start_pos": 576, "end_pos": 626, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 130 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 258, "end_pos": 260 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QQZ7-1", "uniprot_ac": "A0A5G2QQZ7", "uniprot_id": "A0A5G2QQZ7_PIG", "mass": { "chemical_mass": 34641.0, "monoisotopic_mass": 34641.0 }, "refseq": { "ac": "XP_013846920", "name": "olfactory receptor 2M3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013846920" }, "gene_names": [ { "name": "LOC100620490", "type": "recommended", "evidence": [ { "id": "A0A5G2QQZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7" } ] }, { "name": "LOC100620490", "type": "synonym", "evidence": [ { "id": "XP_013846920", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013846920" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QQZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2M3", "type": "synonym", "evidence": [ { "id": "XP_013846920", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013846920" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100620490", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7", "locus": {} } ], "crossref": [ { "id": "A0A5G2QQZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100620490", "url": "https://www.ncbi.nlm.nih.gov/gene/100620490", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100620490", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620490", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FISMAGC", "url": "https://omabrowser.org/oma/group/FISMAGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QQZ7", "url": "https://www.orthodb.org/?gene=A0A5G2QQZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013846920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013846920", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALENQTFNSDFILLGIFDHSPTHIFLFSLVLGIFTVAFMGNTIMILLIYLDTQLHTPMYFLLSQLSLMDLMLICTTVPKMAYNYLSGSTSISFAGCATQIFFYTSLLGCECFLLAVMAYDRNIAICHPLRYTNLMSPKICGLMVASSWILGSTDGVIDAVATFSFSYCGSREIAHFFCDFPFLLIISCNDTSIFEEVLFYCCIIMIVFPVAVVLVSYARVILAVIRMGSGKGRHKAFATCSSHLMVVGMYYGAGLFIYMRPTSNRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVARAFMKVLGKGKN", "length": 310, "header": "tr|A0A5G2QQZ7-1|A0A5G2QQZ7_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100620490 PE=3 SV=1 CANONICAL=A0A5G2QQZ7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7/entry#A0A5G2QQZ7-1", "sequence": { "sequence": "MALENQTFNSDFILLGIFDHSPTHIFLFSLVLGIFTVAFMGNTIMILLIYLDTQLHTPMYFLLSQLSLMDLMLICTTVPKMAYNYLSGSTSISFAGCATQIFFYTSLLGCECFLLAVMAYDRNIAICHPLRYTNLMSPKICGLMVASSWILGSTDGVIDAVATFSFSYCGSREIAHFFCDFPFLLIISCNDTSIFEEVLFYCCIIMIVFPVAVVLVSYARVILAVIRMGSGKGRHKAFATCSSHLMVVGMYYGAGLFIYMRPTSNRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVARAFMKVLGKGKN", "length": 310, "header": "tr|A0A5G2QQZ7-1|A0A5G2QQZ7_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100620490 PE=3 SV=1 CANONICAL=A0A5G2QQZ7-1" }, "locus": { "chromosome": "2", "start_pos": 54868130, "end_pos": 54867201, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069143.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069143.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067342.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067342.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100620490", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620490", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BCE3-1", "protein_name": "Olfactory receptor family 2 subfamily M member 16", "gene_name": "OR2M16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAWEFQTFNSDFILLGIFDHRPTHIFLFSRVLGVSAVAIMGNTLVVLFLYLNAQLHTPMYFLLSQLSLTDLVLISTTIPKMAFNYLSGSKSITMADCATHIFFYASLTGCECFLLAVMAYDCDVATCHPLRYTSLMRLKICGLMTASSWVLGSTDGVIDAVVTFSFSCCGFWVIAHFFCDFPFLLVIQCNDTSIFEEVLFYCCIMMILFPVAIIIASYARVLLTVILMGSGKGRHRAFATCSSHLMVVGTYYGAVLFMYMRPASNHSPTQDRMMSVFYTILTPTLNPLIYSFRNKEVACAFQVFRKGKTGE", "length": 311 }, "evidence": [ { "id": "A0A5G2QQZ7", "url": "https://omabrowser.org/oma/group/A0A5G2QQZ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QQZ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QQZ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QQZ7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QQZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QR02-1", "uniprot_ac": "A0A5G2QR02", "uniprot_id": "A0A5G2QR02_PIG", "mass": { "chemical_mass": 81636.0, "monoisotopic_mass": 81636.0 }, "refseq": {}, "gene_names": [ { "name": "PPP1R3F", "type": "recommended", "evidence": [ { "id": "A0A5G2QR02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 3F", "type": "synonym", "evidence": [ { "id": "A0A5G2QR02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PPP1R3F", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02", "locus": { "chromosome": "X", "start_pos": 43344013, "end_pos": 43328274, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000022584", "url": "https://www.ensembl.org/id/ENSSSCG00000022584" } ] } } ], "crossref": [ { "id": "A0A5G2QR02", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QR02", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000022584", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022584", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR005036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12307", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12307", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12307:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12307:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QR02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QR02-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LU64", "url": "https://www.uniprot.org/uniprotkb/I3LU64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LU64-1", "url": "https://www.uniprot.org/uniprotkb/I3LU64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARTAPVEPPLRHPAPPSPAAGEPRTSVEVAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAAAGQDGDGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGFYLVPTFSLPPASGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVHVRASHDGWASFCDHPARYVPRSPPWAGTGGPGAGDPILDLALGLGPGQASASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLPQQQQLQQPEPQPECQGPVEAEARQLKSCMKPMRRRPHEEELRMKSAEDNAPAVAERPDVQESLGPLVAPTPLRPWPQMTLQVSEVTVTGKPPEEGDARRSSPPVAFTEAPPAPAIRIPLSSSLCGLGGSPRDQASGPDASEGAAGPLLEPSQRKVEATWEVSSENGGGLEVVSGLEEPLGEDTIDQELEQLYLSHLSRLRAAVATGGAGGGGEGPTDGGLSPSHPLGMLTDRDLILKWPGPERALNSALAEEITLHYARLGRGVELIKDTEDPDEEGEGEEGLSIIPSSPEGDTPKESPPEIVSGARSVVAGIGDVWLPWAEGSGCASPGVLGVEGQFTGAPEEGTGKDSGSSRVSRVTVGVTGTPGGMELTTELADSSAPVSGKEPASPVLQGPHLPLPGPLGAEVRPSSLAGPQVSSGDAEGSGPSLEPPKRSPALAAPAESVCILPPQLRGPLTQTLGVLAGLVVVPMALNSGMSLLVLALCLSLAWFS", "length": 790, "header": "tr|A0A5G2QR02-1|A0A5G2QR02_PIG Isoform 1 of Protein phosphatase 1 regulatory subunit 3F OS=Sus scrofa OX=9823 GN=PPP1R3F PE=1 SV=1 CANONICAL=A0A5G2QR02-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QR02-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02/entry#A0A5G2QR02-1", "sequence": { "sequence": "MARTAPVEPPLRHPAPPSPAAGEPRTSVEVAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAAAGQDGDGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGFYLVPTFSLPPASGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVHVRASHDGWASFCDHPARYVPRSPPWAGTGGPGAGDPILDLALGLGPGQASASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLPQQQQLQQPEPQPECQGPVEAEARQLKSCMKPMRRRPHEEELRMKSAEDNAPAVAERPDVQESLGPLVAPTPLRPWPQMTLQVSEVTVTGKPPEEGDARRSSPPVAFTEAPPAPAIRIPLSSSLCGLGGSPRDQASGPDASEGAAGPLLEPSQRKVEATWEVSSENGGGLEVVSGLEEPLGEDTIDQELEQLYLSHLSRLRAAVATGGAGGGGEGPTDGGLSPSHPLGMLTDRDLILKWPGPERALNSALAEEITLHYARLGRGVELIKDTEDPDEEGEGEEGLSIIPSSPEGDTPKESPPEIVSGARSVVAGIGDVWLPWAEGSGCASPGVLGVEGQFTGAPEEGTGKDSGSSRVSRVTVGVTGTPGGMELTTELADSSAPVSGKEPASPVLQGPHLPLPGPLGAEVRPSSLAGPQVSSGDAEGSGPSLEPPKRSPALAAPAESVCILPPQLRGPLTQTLGVLAGLVVVPMALNSGMSLLVLALCLSLAWFS", "length": 790, "header": "tr|A0A5G2QR02-1|A0A5G2QR02_PIG Isoform 1 of Protein phosphatase 1 regulatory subunit 3F OS=Sus scrofa OX=9823 GN=PPP1R3F PE=1 SV=1 CANONICAL=A0A5G2QR02-1" }, "locus": { "chromosome": "X", "start_pos": 43344010, "end_pos": 43328274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070924.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070924.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067347.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067347.1" } ] } }, { "isoform_ac": "I3LU64-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02/entry#I3LU64-1", "sequence": { "sequence": "MKSAEDNAPAVERPDVQESLGPLVAPTPLRPWPQMTLQVSEVTVTGKPPEEGDARRSSPPVAFTEAPPAPAIRIPLSSSLCGLGGSPRDQASGPDASEGAAGPLLEPSQRKVEATWEVSSENGGGLEVVSGLEEPLGEDTIDQELEQLYLSHLSRLRAAVATGGAGGGGEGPTDGGLSPSHPLGMLTDRDLILKWPGPERALNSALAEEITLHYARLGRGVELIKDTEDPDEEGEGEEGLSIIPSSPEGDTPKESPPEIVSGARSVVAGIGDVWLPWAEGSGCASPGVLGVEGQFTGAPEEGTGKDSGSSRVSRVTVGVTGTPGGMELTTELADSSAPVSGKEPASPVLQGPHLPLPGPLGAEVRPSSLAGPQVSSGDAEGSGPSLEPPKRSPALAAPAESVCILPPQLRGPLTQTLGVLAGLVVVPMALNSGMSLLVLALCLSLAWFS", "length": 449, "header": "tr|I3LU64-1|A0A5G2QR02_PIG Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 3F OS=Sus scrofa OX=9823 GN=PPP1R3F PE=1 SV=4 CANONICAL=A0A5G2QR02-1" }, "locus": { "chromosome": "X", "start_pos": 43344010, "end_pos": 43340118, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030816.5", "url": "https://www.ensembl.org/id/ENSSSCT00000030816.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027663.4", "url": "https://www.ensembl.org/id/ENSSSCP00000027663.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 290, "start_aa": "Thr", "end_pos": 290, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr290", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 292, "start_aa": "Thr", "end_pos": 292, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr292", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 514, "start_aa": "Thr", "end_pos": 514, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr514", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 657, "start_aa": "Thr", "end_pos": 657, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr657", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 663, "start_aa": "Thr", "end_pos": 663, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr663", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LU64", "url": "https://www.uniprot.org/uniprotkb/I3LU64" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "protein phosphatase type 1 complex", "id": "GO:0000164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000164", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02" } ], "pmid": "" }, { "name": "glycogen binding", "id": "GO:2001069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001069", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of glycogen biosynthetic process", "id": "GO:0005979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005979", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QR02-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 790, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QR02-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QR02" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QR02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR02" }, { "id": "PS51159", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBM21", "eco_id": "ECO_0000259", "start_pos": 126, "end_pos": 282, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 290, 292, 514, 657, 663 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 278, "end_pos": 280 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QR19-1", "uniprot_ac": "A0A5G2QR19", "uniprot_id": "A0A5G2QR19_PIG", "mass": { "chemical_mass": 34939.0, "monoisotopic_mass": 34939.0 }, "refseq": { "ac": "XP_003125728", "name": "olfactory receptor 10K1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125728" }, "gene_names": [ { "name": "LOC100519710", "type": "recommended", "evidence": [ { "id": "A0A5G2QR19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19" } ] }, { "name": "LOC100519710", "type": "synonym", "evidence": [ { "id": "XP_003125728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125728" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QR19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 10K1", "type": "synonym", "evidence": [ { "id": "XP_003125728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125728" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100519710", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19", "locus": {} } ], "crossref": [ { "id": "A0A5G2QR19", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QR19", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519710", "url": "https://www.ncbi.nlm.nih.gov/gene/100519710", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519710", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519710", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LFLGCCH", "url": "https://omabrowser.org/oma/group/LFLGCCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QR19", "url": "https://www.orthodb.org/?gene=A0A5G2QR19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003125728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125728", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QR19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QR19-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEWVNETTVREFVFLGFSSLAGLQQLLFFIFLLVYLFTLGTNAIIISTIVLDRALHTPMYFFLGVLSCFETCYTFVIVPKMLVDLLAQKKTISFLGCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGYGVCVGLVAAACAGGFTVSLVTTSLIFHLPFHSSNHLHHFFCDISPVLKLASHHSHLSQLVIFMLGVFALVIPLLLILVSYIHIISAILKIPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYASSQDTLISVSYTILTPLFNPMIYSLRNKEFKSALQRAIVQTLYPVN", "length": 313, "header": "tr|A0A5G2QR19-1|A0A5G2QR19_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100519710 PE=3 SV=1 CANONICAL=A0A5G2QR19-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QR19-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19/entry#A0A5G2QR19-1", "sequence": { "sequence": "MEWVNETTVREFVFLGFSSLAGLQQLLFFIFLLVYLFTLGTNAIIISTIVLDRALHTPMYFFLGVLSCFETCYTFVIVPKMLVDLLAQKKTISFLGCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGYGVCVGLVAAACAGGFTVSLVTTSLIFHLPFHSSNHLHHFFCDISPVLKLASHHSHLSQLVIFMLGVFALVIPLLLILVSYIHIISAILKIPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYASSQDTLISVSYTILTPLFNPMIYSLRNKEFKSALQRAIVQTLYPVN", "length": 313, "header": "tr|A0A5G2QR19-1|A0A5G2QR19_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100519710 PE=3 SV=1 CANONICAL=A0A5G2QR19-1" }, "locus": { "chromosome": "4", "start_pos": 91757133, "end_pos": 91756195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087762.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087762.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066497.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066497.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519710", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519710", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8NGX5-1", "protein_name": "Olfactory receptor 10K1", "gene_name": "OR10K1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQVNKTVVREFVVLGFSSLARLQQLLFVIFLLLYLFTLGTNAIIISTIVLDRALHTPMYFFLAILSCSEICYTFVIVPKMLVDLLSQKKTISFLGCAIQMFSFLFFGSSHSFLLAAMGYDRYMAICNPLRYSVLMGHGVCMGLMAAACACGFTVSLVTTSLVFHLPFHSSNQLHHFFCDISPVLKLASQHSGFSQLVIFMLGVFALVIPLLLILVSYIRIISAILKIPSSVGRYKTFSTCASHLIVVTVHYSCASFIYLRPKTNYTSSQDTLISVSYTILTPLFNPMIYSLRNKEFKSALRRTIGQTFYPLS", "length": 313 }, "evidence": [ { "id": "A0A5G2QR19", "url": "https://omabrowser.org/oma/group/A0A5G2QR19/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QR19-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QR19-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QR19" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QR19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR19" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Thr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QR56-1", "uniprot_ac": "A0A5G2QR56", "uniprot_id": "A0A5G2QR56_PIG", "mass": { "chemical_mass": 35103.0, "monoisotopic_mass": 35103.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100739816", "type": "recommended", "evidence": [ { "id": "A0A5G2QR56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QR56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR56", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR56", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100739816", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56", "locus": {} } ], "crossref": [ { "id": "A0A5G2QR56", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QR56", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000051539", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000051539", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YHTTMSN", "url": "https://omabrowser.org/oma/group/YHTTMSN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QR56", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QR56-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGDNQSLTVEFVLTGFADHPELRTILFLVFLAIYLITMVGNLGLVALICTERHLQTPMYIFLGNLALMDSCCSCAVTPKMLENFFSKDRIISLYECMAQWYFLCLAETADCFLLAAMAFDRYVAICNPLMYHTTMSNKLCIKMTTGAFIAGNLHSMIHVGFLFRLTFCRSHQINHFFCDILPLYRLSCVDPYLNELMIFIFSGSIQTLTITIVIISYLFILFTIFTMKSNKGRGKALSTCASHFLSVSIFYGSLLFVYIRPNSVNEEDKDLPLAIFYTLVIPLVNPFIYSLRNKEIINVTKKMIKMS", "length": 308, "header": "tr|A0A5G2QR56-1|A0A5G2QR56_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100739816 PE=3 SV=1 CANONICAL=A0A5G2QR56-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QR56-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56/entry#A0A5G2QR56-1", "sequence": { "sequence": "MTGDNQSLTVEFVLTGFADHPELRTILFLVFLAIYLITMVGNLGLVALICTERHLQTPMYIFLGNLALMDSCCSCAVTPKMLENFFSKDRIISLYECMAQWYFLCLAETADCFLLAAMAFDRYVAICNPLMYHTTMSNKLCIKMTTGAFIAGNLHSMIHVGFLFRLTFCRSHQINHFFCDILPLYRLSCVDPYLNELMIFIFSGSIQTLTITIVIISYLFILFTIFTMKSNKGRGKALSTCASHFLSVSIFYGSLLFVYIRPNSVNEEDKDLPLAIFYTLVIPLVNPFIYSLRNKEIINVTKKMIKMS", "length": 308, "header": "tr|A0A5G2QR56-1|A0A5G2QR56_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100739816 PE=3 SV=1 CANONICAL=A0A5G2QR56-1" }, "locus": { "chromosome": "AEMK02000478.1", "start_pos": 202109, "end_pos": 201186, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072384.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072384.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064531.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064531.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 78, "start_aa": "Thr", "end_pos": 78, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr78", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR56", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR56", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR56", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR56", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR56", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QR56-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 308, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QR56-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QR56" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QR56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR56" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 78 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 299, "end_pos": 301 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QR64-1", "uniprot_ac": "A0A5G2QR64", "uniprot_id": "A0A5G2QR64_PIG", "mass": { "chemical_mass": 32079.0, "monoisotopic_mass": 32079.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QR64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR64", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR64", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR64", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64", "locus": {} } ], "crossref": [ { "id": "A0A5G2QR64", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QR64", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050197", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050197", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QR64", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QR64-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQVVNQSIVTGFVLLGLSDQPKLEKTFFVLILLMYLVILLGNGVLILVTILDSLPLILDGFLTPRKTISFSGCAIQMFLSFAMGATECVLLGMMAFDRYVAICNPLRYPMVMSKATYVPMAASSWLAGGANSLVQISLAVQLPFCGDNVINHFTCEILAVLKLACADISINVISMGVANVIFLGVPVLFIFVSYIFILTTILKIPSAEGRKKAFSTCSAHLTVVILFYGTILFMYAKPKSKDPLGADKQDVSDKLISLLYGVLTPMLNPLIYSLRNKDVKVAVKNLKSQNKSLE", "length": 294, "header": "tr|A0A5G2QR64-1|A0A5G2QR64_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QR64-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QR64-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64/entry#A0A5G2QR64-1", "sequence": { "sequence": "MQVVNQSIVTGFVLLGLSDQPKLEKTFFVLILLMYLVILLGNGVLILVTILDSLPLILDGFLTPRKTISFSGCAIQMFLSFAMGATECVLLGMMAFDRYVAICNPLRYPMVMSKATYVPMAASSWLAGGANSLVQISLAVQLPFCGDNVINHFTCEILAVLKLACADISINVISMGVANVIFLGVPVLFIFVSYIFILTTILKIPSAEGRKKAFSTCSAHLTVVILFYGTILFMYAKPKSKDPLGADKQDVSDKLISLLYGVLTPMLNPLIYSLRNKDVKVAVKNLKSQNKSLE", "length": 294, "header": "tr|A0A5G2QR64-1|A0A5G2QR64_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QR64-1" }, "locus": { "chromosome": "1", "start_pos": 236763485, "end_pos": 236762352, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052465.2", "url": "https://www.ensembl.org/id/ENSSSCT00000052465.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066542.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066542.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR64", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR64", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR64", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR64", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR64", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR64", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QR64-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 294, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QR64-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QR64" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QR64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR64" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 272, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 290, "end_pos": 292 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QR78-1", "uniprot_ac": "A0A5G2QR78", "uniprot_id": "A0A5G2QR78_PIG", "mass": { "chemical_mass": 21762.0, "monoisotopic_mass": 21762.0 }, "refseq": {}, "gene_names": [ { "name": "MTFP1", "type": "recommended", "evidence": [ { "id": "A0A5G2QR78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR78" } ] } ], "protein_names": [ { "name": "Mitochondrial fission process protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2QR78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR78/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial 18 kDa protein", "type": "synonym", "evidence": [ { "id": "A0A5G2QR78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR78/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR78" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MTFP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR78", "locus": { "chromosome": "14", "start_pos": 47396727, "end_pos": 47392665, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010007", "url": "https://www.ensembl.org/id/ENSSSCG00000010007" } ] } } ], "crossref": [ { "id": "A0A5G2QR78", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QR78", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010007", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010007", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR019560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11001:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11001:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10558", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10558", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QR78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QR78-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RFC8", "url": "https://www.uniprot.org/uniprotkb/F1RFC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RFC8-1", "url": "https://www.uniprot.org/uniprotkb/F1RFC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEPPPRGAERDLFRDTWVRYLGYANEVGEAFRSLVPTAVVWLSYGVSSSYVLADAIDKGKKARDVPSPEAGRSTRVTVAVVDTFVWQALASVASQASLSTVCVLPLSTSWALPPAGLWLSASGPLLHWGYWPSPSSSTPSTGQWTSSWTPASASSTPQWRSPAPPDSTLVPGLWVCLFPVPPPSSCQGKWTPSCLGSEALTPE", "length": 204, "header": "tr|A0A5G2QR78-1|A0A5G2QR78_PIG Isoform 1 of Mitochondrial fission process protein 1 OS=Sus scrofa OX=9823 GN=MTFP1 PE=1 SV=1 CANONICAL=A0A5G2QR78-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QR78-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR78/entry#A0A5G2QR78-1", "sequence": { "sequence": "MSEPPPRGAERDLFRDTWVRYLGYANEVGEAFRSLVPTAVVWLSYGVSSSYVLADAIDKGKKARDVPSPEAGRSTRVTVAVVDTFVWQALASVASQASLSTVCVLPLSTSWALPPAGLWLSASGPLLHWGYWPSPSSSTPSTGQWTSSWTPASASSTPQWRSPAPPDSTLVPGLWVCLFPVPPPSSCQGKWTPSCLGSEALTPE", "length": 204, "header": "tr|A0A5G2QR78-1|A0A5G2QR78_PIG Isoform 1 of Mitochondrial fission process protein 1 OS=Sus scrofa OX=9823 GN=MTFP1 PE=1 SV=1 CANONICAL=A0A5G2QR78-1" }, "locus": { "chromosome": "14", "start_pos": 47395719, "end_pos": 47392776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067288.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067288.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066557.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066557.1" } ] } }, { "isoform_ac": "F1RFC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR78/entry#F1RFC8-1", "sequence": { "sequence": "MSEPPPRGAERDLFRDTWVRYLGYANEVGEAFRSLVPTAVVWLSYGVSSSYVLADAIDKGKKARDSFLLLPLLGY", "length": 75, "header": "tr|F1RFC8-1|A0A5G2QR78_PIG Computationally mapped isoform of Mitochondrial fission process protein 1 OS=Sus scrofa OX=9823 GN=MTFP1 PE=1 SV=3 CANONICAL=A0A5G2QR78-1" }, "locus": { "chromosome": "14", "start_pos": 47394070, "end_pos": 47392776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010964.4", "url": "https://www.ensembl.org/id/ENSSSCT00000010964.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010678.4", "url": "https://www.ensembl.org/id/ENSSSCP00000010678.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 139, "start_aa": "Thr", "end_pos": 139, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr139", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RFC8", "url": "https://www.uniprot.org/uniprotkb/F1RFC8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR78" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR78" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR78", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QR78-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 204, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QR78-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QR78" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 139 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRC5-1", "uniprot_ac": "A0A5G2QRC5", "uniprot_id": "A0A5G2QRC5_PIG", "mass": { "chemical_mass": 35024.0, "monoisotopic_mass": 35024.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QRC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5", "locus": {} } ], "crossref": [ { "id": "A0A5G2QRC5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRC5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000042620", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042620", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QRC5", "url": "https://www.orthodb.org/?gene=A0A5G2QRC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QRC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGQNQSSVVDFILLGFSNFPELQGQLFGVFLVVYLVTLMGNAVIILVISLEQSLHVPMYLFLQNLSVVDVSFSAVVMPEMLVVLSTEKTVITFAGCFAQMYFLLLFGGTECFLLGAMAYDRFAAICHPLSYPVLMNQRVFVKLVGSSWVSGIMVATVQTSWVFSFPFCGPNEINHLFCETPPVLELACADTFLFEVYAFTGTVLIVMVPFLLILLSYLRILLAILKMPPTTGRQKAFSTCGSHLTSVTLFYGTASMTYLQPKSGYSPDTKKLLSLAYSLLTPLLNPLIYSLRNSELKRALMKLWRRKADLHTF", "length": 314, "header": "tr|A0A5G2QRC5-1|A0A5G2QRC5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRC5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5/entry#A0A5G2QRC5-1", "sequence": { "sequence": "MKGQNQSSVVDFILLGFSNFPELQGQLFGVFLVVYLVTLMGNAVIILVISLEQSLHVPMYLFLQNLSVVDVSFSAVVMPEMLVVLSTEKTVITFAGCFAQMYFLLLFGGTECFLLGAMAYDRFAAICHPLSYPVLMNQRVFVKLVGSSWVSGIMVATVQTSWVFSFPFCGPNEINHLFCETPPVLELACADTFLFEVYAFTGTVLIVMVPFLLILLSYLRILLAILKMPPTTGRQKAFSTCGSHLTSVTLFYGTASMTYLQPKSGYSPDTKKLLSLAYSLLTPLLNPLIYSLRNSELKRALMKLWRRKADLHTF", "length": 314, "header": "tr|A0A5G2QRC5-1|A0A5G2QRC5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRC5-1" }, "locus": { "chromosome": "9", "start_pos": 1325319, "end_pos": 1324378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071303.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071303.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066602.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066602.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRC5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRC5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRC5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRC5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRD9-1", "uniprot_ac": "A0A5G2QRD9", "uniprot_id": "A0A5G2QRD9_PIG", "mass": { "chemical_mass": 34477.0, "monoisotopic_mass": 34477.0 }, "refseq": { "ac": "XP_020938717", "name": "olfactory receptor 4B1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938717" }, "gene_names": [ { "name": "LOC100523534", "type": "recommended", "evidence": [ { "id": "A0A5G2QRD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9" } ] }, { "name": "LOC100523534", "type": "synonym", "evidence": [ { "id": "XP_020938717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938717" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QRD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4B1-like", "type": "synonym", "evidence": [ { "id": "XP_020938717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938717" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100523534", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9", "locus": {} } ], "crossref": [ { "id": "A0A5G2QRD9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRD9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050589", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050589", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523534", "url": "https://www.ncbi.nlm.nih.gov/gene/100523534", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523534", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523534", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TTIMSQF", "url": "https://omabrowser.org/oma/group/TTIMSQF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QRD9", "url": "https://www.orthodb.org/?gene=A0A5G2QRD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020938717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938717", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QRD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPTNNVTELIITGLFEDPEVQRVCFVVFLPVYLATVVGNGLIVLTVKVSQSLHSPMYFFLSYLSLVEISYSSTVAPKFIADLLSKVKTISLEGCVAQIFFFHFFGVTEIFLLTVMAYDRYVAICKPLHYTVIMSQAVCHRLVAGSWLGGFFHSMVQIIVTVRLPFCGPNVIDHYFCDLHPLFKLACTDTSVEGLVVLANSGLISIFSFLILVSSYIVILVNLRNHSAEGRRKALSTCASHVTVVVLFFGPAIFLYMRPSSTFTEDKLVAVFYTVVTPMLNPIIYTLRNAEVKIAMRRLWGRKVNSGVE", "length": 309, "header": "tr|A0A5G2QRD9-1|A0A5G2QRD9_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100523534 PE=3 SV=1 CANONICAL=A0A5G2QRD9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9/entry#A0A5G2QRD9-1", "sequence": { "sequence": "MAPTNNVTELIITGLFEDPEVQRVCFVVFLPVYLATVVGNGLIVLTVKVSQSLHSPMYFFLSYLSLVEISYSSTVAPKFIADLLSKVKTISLEGCVAQIFFFHFFGVTEIFLLTVMAYDRYVAICKPLHYTVIMSQAVCHRLVAGSWLGGFFHSMVQIIVTVRLPFCGPNVIDHYFCDLHPLFKLACTDTSVEGLVVLANSGLISIFSFLILVSSYIVILVNLRNHSAEGRRKALSTCASHVTVVVLFFGPAIFLYMRPSSTFTEDKLVAVFYTVVTPMLNPIIYTLRNAEVKIAMRRLWGRKVNSGVE", "length": 309, "header": "tr|A0A5G2QRD9-1|A0A5G2QRD9_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100523534 PE=3 SV=1 CANONICAL=A0A5G2QRD9-1" }, "locus": { "chromosome": "2", "start_pos": 14493742, "end_pos": 14492816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075390.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075390.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060841.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060841.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523534", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523534", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K8X9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4b13b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANENNVTELIFTGLFQDPEVQKACFVLFLPVYVATLLGNSLIIVAVSASKTLHSPMYFFLSSLSLVEICYSSTIVPKFITDLLAKIKTISLKGCLTQIFFSHFLGVVEVILLVVMAYDRYVAICKPLHYMNIMSRQVCHMLVAGSWLGGLIHSIIQILITIPLPFCGPNVIDHYFCDLQPLFKLACTDTFLEGVIVMANSGLISIISLFILVFSYAIILVSLRNHSAEGRRKALATCASHITVVILFFGPGAFIYMRPSSTFTEDKLVSVFYTVITPMLNPIVYTLRNTEMKNAIRMFWNQKEN", "length": 305 }, "evidence": [ { "id": "A0A5G2QRD9", "url": "https://omabrowser.org/oma/group/A0A5G2QRD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VG62-1", "protein_name": "Olfactory receptor", "gene_name": "Or4b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVHENNVTELIFTGLFQDPEVQKVCFVLFLPVYLATLLGNGLIFVTVSISKTLHSPMYFFLSSLSLVEICYSSTVAPKFITDLLAKVKTISLKGCLTQIFFFHFFGVVEIILLVMMAYDRYVAICKPLHYMIIMSRQVCHMLVAGSWLGGLIHSIIQIIITIPLPFCGPNVIDHYFCDLHPLLKLACSDTFMERFIVMANSGLFSIISLFILVSSYAVILISLRKRSAEGRRKALSTCASHITVVILYFGPGAFIYMRPSSAFTEDKLVSVFYTVITPMLNPIVYTLRNTEMKNAIRMFWSQKDK", "length": 305 }, "evidence": [ { "id": "A0A5G2QRD9", "url": "https://omabrowser.org/oma/group/A0A5G2QRD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRD9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRD9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRD9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRD9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRI9-1", "uniprot_ac": "A0A5G2QRI9", "uniprot_id": "A0A5G2QRI9_PIG", "mass": { "chemical_mass": 138276.0, "monoisotopic_mass": 138276.0 }, "refseq": {}, "gene_names": [ { "name": "DIAPH1", "type": "recommended", "evidence": [ { "id": "A0A5G2QRI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ] } ], "protein_names": [ { "name": "Protein diaphanous homolog 1", "type": "recommended", "evidence": [ { "id": "A0A5G2QRI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9/entry#names_and_taxonomy" } ] }, { "name": "Diaphanous-related formin-1", "type": "synonym", "evidence": [ { "id": "A0A5G2QRI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9/entry#names_and_taxonomy" } ] }, { "name": "Diaphanous-related formin-2", "type": "synonym", "evidence": [ { "id": "A0A5G2QRI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9/entry#names_and_taxonomy" } ] }, { "name": "Protein diaphanous homolog 2", "type": "synonym", "evidence": [ { "id": "A0A5G2QRI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DIAPH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9", "locus": { "chromosome": "2", "start_pos": 143158585, "end_pos": 143271147, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014387", "url": "https://www.ensembl.org/id/ENSSSCG00000014387" } ] } } ], "crossref": [ { "id": "A0A5G2QRI9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRI9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014387", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014387", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR010465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45691", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45691", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45691:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45691:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06345", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06345", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06346", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06346", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06367", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06367", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06371", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06371", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6785631", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6785631", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013026", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013026", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7C9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RMT5", "url": "https://www.uniprot.org/uniprotkb/F1RMT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RMT5-1", "url": "https://www.uniprot.org/uniprotkb/F1RMT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPGGGLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKFTLKRLMADELERFTSMRIKKEKEKPNSANRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEKQQPLREKDIIIKREMVSQYLHTSKAGMSQKESSRSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEMERFQPLLDGLKSGTSIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQELREIENDDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMDDFSEVFQILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIDIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLHDLQGEKNTLDSEKQQITTEKQDLEAEVSQLTSEVAKLSKELEDAKKEVASLSAAAAAAAPPVRAALPPAPPLPGDSSGGPGPVVPTSPPLLEGGSPVPAPLLPGGEAIPPPPPPPPPLPGAPCIPPPPPLPGAPCIPPPPPLPGVPDVPPPPPLPGVPGVPGVPPPPPLPGVPGVPPPPPPLPGGPGMLPPPPPLPGGLPPPPPFPGGPGIPPPLPVGFGVPAAPVLPFGLIPKKVYKPEVQLRRPNWSKFVAEDLSQDCFWTKVKEDRFENNDLFAKLTLTFSAQTKTKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGAVPRLRPRLNAILFRLQFGEQVENIKPEIVSVTAACEETRKSESFASLLELTLLVGNYMNAGSRNAGAFGFSISFLCKLRDTKSTDQKMTLLHFLAELCENDHPDVLRFPEELAHVEKASRVSAENLQKNLDQMKKQIADVERDIQNFPAATDEKDKFVEKMTIFVKDAQEQYNKLRLMHSNMETLYKELGEYFLFDPKKVAVEEFFMDLHNFKNMFVQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRRKRGPRQANKKVACAVTLEGLKDDALASVPAKISRKSEQVPTILEEPKELLGRAS", "length": 1243, "header": "tr|A0A5G2QRI9-1|A0A5G2QRI9_PIG Isoform 1 of Protein diaphanous homolog 1 OS=Sus scrofa OX=9823 GN=DIAPH1 PE=1 SV=2 CANONICAL=A0A5G2QRI9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9/entry#A0A5G2QRI9-1", "sequence": { "sequence": "MEPPGGGLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKFTLKRLMADELERFTSMRIKKEKEKPNSANRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEKQQPLREKDIIIKREMVSQYLHTSKAGMSQKESSRSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEMERFQPLLDGLKSGTSIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQELREIENDDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMDDFSEVFQILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIDIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLHDLQGEKNTLDSEKQQITTEKQDLEAEVSQLTSEVAKLSKELEDAKKEVASLSAAAAAAAPPVRAALPPAPPLPGDSSGGPGPVVPTSPPLLEGGSPVPAPLLPGGEAIPPPPPPPPPLPGAPCIPPPPPLPGAPCIPPPPPLPGVPDVPPPPPLPGVPGVPGVPPPPPLPGVPGVPPPPPPLPGGPGMLPPPPPLPGGLPPPPPFPGGPGIPPPLPVGFGVPAAPVLPFGLIPKKVYKPEVQLRRPNWSKFVAEDLSQDCFWTKVKEDRFENNDLFAKLTLTFSAQTKTKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGAVPRLRPRLNAILFRLQFGEQVENIKPEIVSVTAACEETRKSESFASLLELTLLVGNYMNAGSRNAGAFGFSISFLCKLRDTKSTDQKMTLLHFLAELCENDHPDVLRFPEELAHVEKASRVSAENLQKNLDQMKKQIADVERDIQNFPAATDEKDKFVEKMTIFVKDAQEQYNKLRLMHSNMETLYKELGEYFLFDPKKVAVEEFFMDLHNFKNMFVQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRRKRGPRQANKKVACAVTLEGLKDDALASVPAKISRKSEQVPTILEEPKELLGRAS", "length": 1243, "header": "tr|A0A5G2QRI9-1|A0A5G2QRI9_PIG Isoform 1 of Protein diaphanous homolog 1 OS=Sus scrofa OX=9823 GN=DIAPH1 PE=1 SV=2 CANONICAL=A0A5G2QRI9-1" }, "locus": { "chromosome": "2", "start_pos": 143270994, "end_pos": 143160184, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071344.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071344.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067534.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067534.2" } ] } }, { "isoform_ac": "A0A5G2R7C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9/entry#A0A5G2R7C9-1", "sequence": { "sequence": "MEPPGGGLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKFTLKRLMADELERFTSMRIKKEKEKPNSANRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEKQQPLREKDIIIKREMVSQYLHTSKAGMSQKESSRSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEMERFQPLLDGLKSGTSIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQELREIENDDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMEYPFIDCEVFQILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIDIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLHDLQGEKNTLDSEKQQITTEKQDLEAEVSQLTSEVAKLSKELEDAKKEVASLSAAAAAAAPPVRAALPPAPPLPGDSSGGPGPVVPTSPPLLEGGSPVPAPLLPGGEAIPPPPPPPPPLPGAPCIPPPPPLPGAPCIPPPPPLPGVPDVPPPPPLPGVPGVPGVPPPPPLPGVPGVPPPPPPLPGGPGMLPPPPPLPGGLPPPPPFPGGPGIPPPLPVGFGVPAAPVLPFGLIPKKVYKPEVQLRRPNWSKFVAEDLSQDCFWTKVKEDRFENNDLFAKLTLTFSAQTKTSKGKNTEELFRWVS", "length": 820, "header": "tr|A0A5G2R7C9-1|A0A5G2QRI9_PIG Computationally mapped isoform of Protein diaphanous homolog 1 OS=Sus scrofa OX=9823 GN=DIAPH1 PE=1 SV=2 CANONICAL=A0A5G2QRI9-1" }, "locus": { "chromosome": "2", "start_pos": 143270994, "end_pos": 143223574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083080.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083080.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066506.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066506.2" } ] } }, { "isoform_ac": "A0A8W4FEZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9/entry#A0A8W4FEZ8-1", "sequence": { "sequence": "MEPPGGGLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKFTLKRLMADELERFTSMRIKKEKEKPNSANRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEKQQPLREKDIIIKREMVSQYLHTSKAGMSQKESSRSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEMERFQPLLDGLKSGTSIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQELREIENDDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMDDFSEVFQILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIDIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLHDLQGEKNTLDSEKQQITTEKQDLEAEVSQLTSEVAKLSKELEDAKKEVASLSAAAAAAAPPVRAALPPAPPLPGDSSGGPGPVVPTSPPLLEGGSPVPAPLLPGGEAIPPPPPPPPPLPGAPCIPPPPPLPGAPCIPPPPPLPGVPDVPPPPPLPGVPGVPPPPPPLPGGPGMLPPPPPLPGGLPPPPPFPGGPGIPPPLPVGFGVPAAPVLPFGLIPKKVYKPEVQLRRPNWSKFVAEDLSQDCFWTKVKEDRFENNDLFAKLTLTFSAQTKSESLPL", "length": 793, "header": "tr|A0A8W4FEZ8-1|A0A5G2QRI9_PIG Computationally mapped isoform of Protein diaphanous homolog 1 OS=Sus scrofa OX=9823 GN=DIAPH1 PE=1 SV=1 CANONICAL=A0A5G2QRI9-1" }, "locus": { "chromosome": "2", "start_pos": 143270994, "end_pos": 143224069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096548.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096548.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077437.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077437.1" } ] } }, { "isoform_ac": "F1RMT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9/entry#F1RMT5-1", "sequence": { "sequence": "MEPPGGGLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKFLERFTSMRIKKEKEKPNSANRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEKQQPLREKDIIIKREMVSQYLHTSKAGMSQKESSRSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEMERFQPLLDGLKSGTSIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQELREIENDDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMEYPFIDWLQDREDLQLQILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIDIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLHDLQGEKNTLDSEKQQITTEKQDLEAEVSQLTSEVAKLSKELEDAKKEVASLSAAAAAAAPPVRAALPPAPPLPGDSSGGPGPVVPTSPPLLEGGSPVPAPLLPGGEAIPPPPPPPPPLPGAPCIPPPPPLPGAPCIPPPPPLPGVPDVPPPPPLPGVPGVPGVPPPPPLPGVPGVPPPPPPLPGGPGMLPPPPPLPGGLPPPPPFPGGPGIPPPLPVGFGVPAAPVLPFGLIPKKVYKPEVQLRRPNWSKFVAEDLSQDCFWTKVKEDRFENNDLFAKLTLTFSAQTKSDQEGSGRWRRKEICAKEKSERVKGAGFKDGPESLNLSGFLPHALSRD", "length": 850, "header": "tr|F1RMT5-1|A0A5G2QRI9_PIG Computationally mapped isoform of Protein diaphanous homolog 1 OS=Sus scrofa OX=9823 GN=DIAPH1 PE=1 SV=5 CANONICAL=A0A5G2QRI9-1" }, "locus": { "chromosome": "2", "start_pos": 143270994, "end_pos": 143171607, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015724.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015724.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015309.5", "url": "https://www.ensembl.org/id/ENSSSCP00000015309.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 600, "start_aa": "Thr", "end_pos": 600, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr600", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEZ8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-SSC-6785631", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6785631", "resource": "Reactome", "description": "ERBB2 Regulates Cell Motility" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-SSC-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-SSC-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-SSC-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "regulation of microtubule-based process", "id": "GO:0032886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "regulation of cytoskeleton organization", "id": "GO:0051493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051493", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "regulation of release of sequestered calcium ion into cytosol", "id": "GO:0051279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051279", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "cellular response to histamine", "id": "GO:0071420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071420", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "protein localization to microtubule", "id": "GO:0035372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035372", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 761, "end_pos": 763, "annotation": "n_glycosylation_sequon" }, { "start_pos": 834, "end_pos": 836, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRI9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1243, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRI9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRI9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" }, { "id": "PS51231", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51231" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DAD", "eco_id": "ECO_0000259", "start_pos": 1169, "end_pos": 1197, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QRI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" }, { "id": "PS51444", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51444" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FH2", "eco_id": "ECO_0000259", "start_pos": 747, "end_pos": 1146, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QRI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI9" }, { "id": "PS51232", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51232" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GBD/FH3", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 449, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 600 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 70, "end_pos": 72 }, { "start_pos": 761, "end_pos": 763 }, { "start_pos": 834, "end_pos": 836 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRM8-1", "uniprot_ac": "A0A5G2QRM8", "uniprot_id": "A0A5G2QRM8_PIG", "mass": { "chemical_mass": 19633.0, "monoisotopic_mass": 19633.0 }, "refseq": { "ac": "XP_020935707", "name": "EKC/KEOPS complex subunit LAGE3-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935707" }, "gene_names": [ { "name": "LOC102166335", "type": "synonym", "evidence": [ { "id": "XP_020935707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935707" } ] } ], "protein_names": [ { "name": "L antigen family member 3", "type": "recommended", "evidence": [ { "id": "A0A5G2QRM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8/entry#names_and_taxonomy" } ] }, { "name": "EKC/KEOPS complex subunit LAGE3-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020935707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935707" } ] } ], "function": [ { "annotation": "Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRM8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8#function" }, { "database": "UniProtKB", "id": "ARBA00053047", "url": "https://www.uniprot.org/uniprotkb/ARBA00053047#function" }, { "database": "UniProtKB", "id": "A0A8W4FAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAW9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRM8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QRM8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRM8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000049540", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000049540", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "102166335", "url": "https://www.ncbi.nlm.nih.gov/gene/102166335", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015419", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015419", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:102166335", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102166335", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QRM8", "url": "https://www.orthodb.org/?gene=A0A5G2QRM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31283", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31283", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31283:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31283:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09341", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09341", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020935707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935707", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QRM8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQAPDDGEGGAGTPSGQHSSQLPDCHSSSGSPEGEGGPGNEGAVIKAALATPRPDQAPPAQGPGGDAVRMAVGPGSGPLEFTLTVTLRSPLEADMARRSLIPDAQRHQHGIQREFTVNGSALAIRWTAADLALFRSSINSSLDQLCLVIRNIRRFVPPPAKSLREERGLRPNFVSPTRQCIGNSNLE", "length": 187, "header": "tr|A0A5G2QRM8-1|A0A5G2QRM8_PIG Isoform 1 of L antigen family member 3 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRM8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8/entry#A0A5G2QRM8-1", "sequence": { "sequence": "MQAPDDGEGGAGTPSGQHSSQLPDCHSSSGSPEGEGGPGNEGAVIKAALATPRPDQAPPAQGPGGDAVRMAVGPGSGPLEFTLTVTLRSPLEADMARRSLIPDAQRHQHGIQREFTVNGSALAIRWTAADLALFRSSINSSLDQLCLVIRNIRRFVPPPAKSLREERGLRPNFVSPTRQCIGNSNLE", "length": 187, "header": "tr|A0A5G2QRM8-1|A0A5G2QRM8_PIG Isoform 1 of L antigen family member 3 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRM8-1" }, "locus": { "chromosome": "X", "start_pos": 125151874, "end_pos": 125150810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084263.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084263.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066727.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066727.1" } ] } }, { "isoform_ac": "A0A8W4FAW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8/entry#A0A8W4FAW9-1", "sequence": { "sequence": "MQAPDDGEGGAGTPSGQHSSQLPDCHSSSGSPEGEGGPGNEGAVIKAALATPRPDQAPPAQGPGGDAVRMAVGPGSGPLEFTLTVTLRSPLEADMARRSLIPDAQRHQHGIQREFTVNGSALAIRWTAADLALFRSSINSSLDQLCLVIRNIRRFVIKFFPEYFFI", "length": 166, "header": "tr|A0A8W4FAW9-1|A0A5G2QRM8_PIG Computationally mapped isoform of L antigen family member 3 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRM8-1" }, "locus": { "chromosome": "X", "start_pos": 125152770, "end_pos": 125150810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091773.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091773.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075438.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075438.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAW9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102166335", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102166335", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRM8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRM8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8" } ], "pmid": "" }, { "name": "EKC/KEOPS complex", "id": "GO:0000408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000408", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRM8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRM8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8" } ], "pmid": "" }, { "name": "tRNA threonylcarbamoyladenosine metabolic process", "id": "GO:0070525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRM8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRM8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 187, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRM8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRM8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 139, "end_pos": 141 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRN0-1", "uniprot_ac": "A0A5G2QRN0", "uniprot_id": "A0A5G2QRN0_PIG", "mass": { "chemical_mass": 45743.0, "monoisotopic_mass": 45743.0 }, "refseq": { "ac": "XP_020953799", "name": "Krueppel-like factor 15 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020953799" }, "gene_names": [ { "name": "KLF15", "type": "recommended", "evidence": [ { "id": "A0A5G2QRN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ] }, { "name": "KLF15", "type": "synonym", "evidence": [ { "id": "XP_020953799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020953799" } ] } ], "protein_names": [ { "name": "Krueppel-like factor 15", "type": "recommended", "evidence": [ { "id": "A0A5G2QRN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-like factor 15 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020953799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020953799" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KLF15", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0", "locus": { "chromosome": "7", "start_pos": 53877818, "end_pos": 53889144, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036742", "url": "https://www.ensembl.org/id/ENSSSCG00000036742" } ] } } ], "crossref": [ { "id": "A0A5G2QRN0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRN0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000036742", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036742", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21580", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21580", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100174957", "url": "https://www.ncbi.nlm.nih.gov/gene/100174957", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020953799", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020953799", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQEQPGWWPEAAATSTASMVDHLLPVDESFSSPKCPVGYLGDRLASGRSYHMLPSPLSEDDSDASSLCSCASPDSQALCSCYSGGSGAEGQDSILDFLLSQATLGSGGGCGSIGANGGPVAWGTWRKTPAPVKGEHFCFPEFPAGDPDDVPRPFQPTLEEIEEFLEENMEPGVKEAPESHGKDLETCGQLSTGLHRSHLHPGSGGRERGAALSGASAGSSQGTGGGPTPDGPIPVLLQIQPMQVKRECGAEPASPGQAPESVKVAQLLVNIQGQTFTLVPQVVPSSSLNLPSKFVRIAPVPIAAKPIGSGPLGPGSTSLLMGQKFPKNPAAELIKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHVKVHRFPRSSRAARP", "length": 431, "header": "tr|A0A5G2QRN0-1|A0A5G2QRN0_PIG Isoform 1 of Krueppel-like factor 15 OS=Sus scrofa OX=9823 GN=KLF15 PE=4 SV=1 CANONICAL=A0A5G2QRN0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0/entry#A0A5G2QRN0-1", "sequence": { "sequence": "MEQEQPGWWPEAAATSTASMVDHLLPVDESFSSPKCPVGYLGDRLASGRSYHMLPSPLSEDDSDASSLCSCASPDSQALCSCYSGGSGAEGQDSILDFLLSQATLGSGGGCGSIGANGGPVAWGTWRKTPAPVKGEHFCFPEFPAGDPDDVPRPFQPTLEEIEEFLEENMEPGVKEAPESHGKDLETCGQLSTGLHRSHLHPGSGGRERGAALSGASAGSSQGTGGGPTPDGPIPVLLQIQPMQVKRECGAEPASPGQAPESVKVAQLLVNIQGQTFTLVPQVVPSSSLNLPSKFVRIAPVPIAAKPIGSGPLGPGSTSLLMGQKFPKNPAAELIKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHVKVHRFPRSSRAARP", "length": 431, "header": "tr|A0A5G2QRN0-1|A0A5G2QRN0_PIG Isoform 1 of Krueppel-like factor 15 OS=Sus scrofa OX=9823 GN=KLF15 PE=4 SV=1 CANONICAL=A0A5G2QRN0-1" }, "locus": { "chromosome": "7", "start_pos": 53888895, "end_pos": 53878806, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085657.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085657.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064686.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064686.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 229, "start_aa": "Thr", "end_pos": 229, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr229", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ], "pmid": "" }, { "name": "cardiac muscle hypertrophy in response to stress", "id": "GO:0014898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014898", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ], "pmid": "" }, { "name": "podocyte differentiation", "id": "GO:0072112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072112", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRN0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 431, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRN0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRN0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRN0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 338, "end_pos": 367, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 229 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRP7-1", "uniprot_ac": "A0A5G2QRP7", "uniprot_id": "A0A5G2QRP7_PIG", "mass": { "chemical_mass": 11432.0, "monoisotopic_mass": 11432.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A5G2QRP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7", "locus": {} } ], "crossref": [ { "id": "A0A5G2QRP7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000047251", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000047251", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR010548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15186", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15186", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15186:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15186:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QRP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQSSQAPGLQEESLHGSSVELYFGNNGNGSIIPDSVSVYNGNMEKILLDAQHESGQSSSKSSHCDNPPRSQTQDNNREKINLCQIKKKKIQTLKCQTSQVSRI", "length": 104, "header": "tr|A0A5G2QRP7-1|A0A5G2QRP7_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRP7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7/entry#A0A5G2QRP7-1", "sequence": { "sequence": "MPQSSQAPGLQEESLHGSSVELYFGNNGNGSIIPDSVSVYNGNMEKILLDAQHESGQSSSKSSHCDNPPRSQTQDNNREKINLCQIKKKKIQTLKCQTSQVSRI", "length": 104, "header": "tr|A0A5G2QRP7-1|A0A5G2QRP7_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRP7-1" }, "locus": { "chromosome": "5", "start_pos": 78452743, "end_pos": 78451437, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084714.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084714.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067595.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067595.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7" } ], "pmid": "" }, { "name": "mitochondrial outer membrane permeabilization", "id": "GO:0097345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097345", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7" } ], "pmid": "" }, { "name": "positive regulation of programmed cell death", "id": "GO:0043068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043068", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRP7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 104, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRP7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRP7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRR3-1", "uniprot_ac": "A0A5G2QRR3", "uniprot_id": "A0A5G2QRR3_PIG", "mass": { "chemical_mass": 33746.0, "monoisotopic_mass": 33746.0 }, "refseq": { "ac": "XP_020917979", "name": "olfactory receptor 2AG1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020917979" }, "gene_names": [ { "name": "LOC100738864", "type": "synonym", "evidence": [ { "id": "XP_020917979", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020917979" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QRR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2AG1-like", "type": "synonym", "evidence": [ { "id": "XP_020917979", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020917979" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3", "locus": {} } ], "crossref": [ { "id": "A0A5G2QRR3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044796", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044796", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100738864", "url": "https://www.ncbi.nlm.nih.gov/gene/100738864", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100738864", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738864", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YELFVYV", "url": "https://omabrowser.org/oma/group/YELFVYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QRR3", "url": "https://www.orthodb.org/?gene=A0A5G2QRR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020917979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020917979", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QRR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHWNSTLGSGFILVGILNDSGSPGLLCAAIAVLYMLALTSNGLLLLVITVDARLHAPMYLLLGQLSLMDLLFTSVVTPKALVDFLLGESTISFGGCALQMFLALALGGAEDLLLAFMAYDRYVAICHPLSYMVLMRPGVCWLLVATSWVLASLSALGHTLYTMHYPFCRSRKISHLLCEIPPLLKLACADTSGYELMVYVMGVTFLIPPLVAVLASYTLILLTVLHMPSSEGRRKALVTCSSHLTVVGMFYGAATVMYVLPSSLHSPGQDRITSVFYTVVTPALNPLIYSLRNKEVLGAWRRVLGRRVL", "length": 310, "header": "tr|A0A5G2QRR3-1|A0A5G2QRR3_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRR3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3/entry#A0A5G2QRR3-1", "sequence": { "sequence": "MEHWNSTLGSGFILVGILNDSGSPGLLCAAIAVLYMLALTSNGLLLLVITVDARLHAPMYLLLGQLSLMDLLFTSVVTPKALVDFLLGESTISFGGCALQMFLALALGGAEDLLLAFMAYDRYVAICHPLSYMVLMRPGVCWLLVATSWVLASLSALGHTLYTMHYPFCRSRKISHLLCEIPPLLKLACADTSGYELMVYVMGVTFLIPPLVAVLASYTLILLTVLHMPSSEGRRKALVTCSSHLTVVGMFYGAATVMYVLPSSLHSPGQDRITSVFYTVVTPALNPLIYSLRNKEVLGAWRRVLGRRVL", "length": 310, "header": "tr|A0A5G2QRR3-1|A0A5G2QRR3_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRR3-1" }, "locus": { "chromosome": "9", "start_pos": 2790302, "end_pos": 2789373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097829.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097829.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076424.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076424.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 282, "start_aa": "Thr", "end_pos": 282, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr282", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100738864", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738864", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LWD1-1", "protein_name": "Olfactory receptor 2AG1", "gene_name": "LOC100752260", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPWNSTLRSDFILVGILDNSGSPELLCAAFTALYMLALTSNGLLLLVITLDARLHVPMYFLLGQLSLMDLLFTSVVTPKAVIDFLLRDNTITFESCALQMFLALTLGGAEDLLLAFMAYDRYVAICHPLNYMIFMRPSICWLMVATSWILASLMALGYTTYTMQYPFCKSREIRHLLCEIPPLLKLACADISTYELMVYVMGVTFLIPPLSAILVSYTLILFTVLHMPSNEGRKKAFVTCSSHLTVVGMFYGAATFMYVLPSSFHSPRQDNIISVFYTIVTPALNPLIYSLRNKEVTGALIRVLGRYIMPANPTL", "length": 316 }, "evidence": [ { "id": "A0A5G2QRR3", "url": "https://omabrowser.org/oma/group/A0A5G2QRR3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9EPF7-1", "protein_name": "Olfactory receptor family 2 subfamily AG member 1", "gene_name": "Or2ag1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPWNSTLGTDFNLVGILDDSGSPELLCATFTALYMLALISNGLLILVITMDARLHVPMYFLLGQLSLMDLLFTSVVTPKAVIDFLLRDNTISFEGCSLQMFLALTLGGAEDLLLAFMAYDRYVAICHPLNYMIFMRPSICWLMVATSWVLASLMALGYTTYTMQYSYCKSRKIRHLLCEIPPLLKLACADTSKYELMVYVMGVTFLIPPLAAILASYSLILFTVLHMPSNEGRKKALVTCSSHLTVVGMFYGAATFMYVLPNSFHSPRQDNIISVFYTIVTPALNPLIYSLRNKEVTGALIRVLGRYIVPAHPTL", "length": 316 }, "evidence": [ { "id": "A0A5G2QRR3", "url": "https://omabrowser.org/oma/group/A0A5G2QRR3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H205-1", "protein_name": "Olfactory receptor 2AG1", "gene_name": "OR2AG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELWNFTLGSGFILVGILNDSGSPELLCATITILYLLALISNGLLLLAITMEARLHMPMYLLLGQLSLMDLLFTSVVTPKALADFLRRENTISFGGCALQMFLALTMGGAEDLLLAFMAYDRYVAICHPLTYMTLMSSRACWLMVATSWILASLSALIYTVYTMHYPFCRAQEIRHLLCEIPHLLKVACADTSRYELMVYVMGVTFLIPSLAAILASYTQILLTVLHMPSNEGRKKALVTCSSHLTVVGMFYGAATFMYVLPSSFHSTRQDNIISVFYTIVTPALNPLIYSLRNKEVMRALRRVLGKYMLPAHSTL", "length": 316 }, "evidence": [ { "id": "A0A5G2QRR3", "url": "https://omabrowser.org/oma/group/A0A5G2QRR3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRR3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRR3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRR3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRR3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 282 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRS4-1", "uniprot_ac": "A0A5G2QRS4", "uniprot_id": "A0A5G2QRS4_PIG", "mass": { "chemical_mass": 43837.0, "monoisotopic_mass": 43837.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "exodeoxyribonuclease III", "type": "recommended", "evidence": [ { "id": "A0A5G2QRS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4/entry#names_and_taxonomy" } ] }, { "name": "3.1.11.2", "type": "synonym", "evidence": [ { "id": "A0A5G2QRS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4", "locus": {} } ], "crossref": [ { "id": "A0A5G2QRS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041491", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041491", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09076", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09076", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22748", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22748", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22748:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22748:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QRS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAINNHLSIITLNVNGLNAPIKRHRVAEWIKRQKPSICCLQETHLRTKDTYRLKVKGWGKIFHANRHDRKAGVATLISDKIDFKTKDIKKDKEGHYLMIKGSIQGEDVTIVNIYAPNTGAPRYTQQILTDIKGDIDENTIIVGELNTPLTSMDRSSRQKTNKATEILKETIEKLDLIDIFRTLHPKKAGYTFFSNAHGTFSRIDHILGHKANLNKFRSIEIISSIFSDHNAMKLEINHGKSKEKKPTPWRLNNMLLKNQWVNEEIKKEIKNYLETNDNEDTTSQNLWDAAKAVLRGKFIAIQAFLKKEERSQIDNLTLHLNELEKEQKSPKVSRRKEIIKIKEEINKIETQKTIEKINKTKSWFFEKLLHCKGNQKEN", "length": 378, "header": "tr|A0A5G2QRS4-1|A0A5G2QRS4_PIG Isoform 1 of exodeoxyribonuclease III OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2QRS4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4/entry#A0A5G2QRS4-1", "sequence": { "sequence": "MAINNHLSIITLNVNGLNAPIKRHRVAEWIKRQKPSICCLQETHLRTKDTYRLKVKGWGKIFHANRHDRKAGVATLISDKIDFKTKDIKKDKEGHYLMIKGSIQGEDVTIVNIYAPNTGAPRYTQQILTDIKGDIDENTIIVGELNTPLTSMDRSSRQKTNKATEILKETIEKLDLIDIFRTLHPKKAGYTFFSNAHGTFSRIDHILGHKANLNKFRSIEIISSIFSDHNAMKLEINHGKSKEKKPTPWRLNNMLLKNQWVNEEIKKEIKNYLETNDNEDTTSQNLWDAAKAVLRGKFIAIQAFLKKEERSQIDNLTLHLNELEKEQKSPKVSRRKEIIKIKEEINKIETQKTIEKINKTKSWFFEKLLHCKGNQKEN", "length": 378, "header": "tr|A0A5G2QRS4-1|A0A5G2QRS4_PIG Isoform 1 of exodeoxyribonuclease III OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2QRS4-1" }, "locus": { "chromosome": "9", "start_pos": 27676681, "end_pos": 27673602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091027.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091027.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067475.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067475.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4" } ], "pmid": "" }, { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4" } ], "pmid": "" }, { "name": "DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0003906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003906", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4" } ], "pmid": "" }, { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4" } ], "pmid": "" }, { "name": "double-stranded DNA 3'-5' DNA exonuclease activity", "id": "GO:0008311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008311", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRS4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 378, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRS4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRS4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRS4" }, { "id": "PF03372", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endonuclease/exonuclease/phosphatase", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 229, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 315, "end_pos": 317 }, { "start_pos": 358, "end_pos": 360 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRT1-1", "uniprot_ac": "A0A5G2QRT1", "uniprot_id": "A0A5G2QRT1_PIG", "mass": { "chemical_mass": 22351.0, "monoisotopic_mass": 22351.0 }, "refseq": {}, "gene_names": [ { "name": "DPRX", "type": "recommended", "evidence": [ { "id": "A0A5G2QRT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1" } ] } ], "protein_names": [ { "name": "Divergent-paired related homeobox", "type": "synonym", "evidence": [ { "id": "A0A5G2QRT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DPRX", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1", "locus": { "chromosome": "6", "start_pos": 56561189, "end_pos": 56568363, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000046881", "url": "https://www.ensembl.org/id/ENSSSCG00000046881" } ] } } ], "crossref": [ { "id": "A0A5G2QRT1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000046881", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000046881", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45793:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45793:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QRT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNPGNLSKEKCQSHPHRKRTVFTKKQLADMNLFFNTNPYPTPSLQREMASKMEMHPRALQVWFKNRRAKLEKAKCKDFQPAHEAQREAQRRPLAEARVRISSSRGQTTTPPRNPHAASPASLVYTDHPRPSFQLSIWTSLKTLTHQPLGHKMVHFGCCQDPNIYCLSPISESQAPSTSFCSNSLGLLSSQRTQRR", "length": 196, "header": "tr|A0A5G2QRT1-1|A0A5G2QRT1_PIG Isoform 1 of Divergent-paired related homeobox OS=Sus scrofa OX=9823 GN=DPRX PE=4 SV=1 CANONICAL=A0A5G2QRT1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1/entry#A0A5G2QRT1-1", "sequence": { "sequence": "MSNPGNLSKEKCQSHPHRKRTVFTKKQLADMNLFFNTNPYPTPSLQREMASKMEMHPRALQVWFKNRRAKLEKAKCKDFQPAHEAQREAQRRPLAEARVRISSSRGQTTTPPRNPHAASPASLVYTDHPRPSFQLSIWTSLKTLTHQPLGHKMVHFGCCQDPNIYCLSPISESQAPSTSFCSNSLGLLSSQRTQRR", "length": 196, "header": "tr|A0A5G2QRT1-1|A0A5G2QRT1_PIG Isoform 1 of Divergent-paired related homeobox OS=Sus scrofa OX=9823 GN=DPRX PE=4 SV=1 CANONICAL=A0A5G2QRT1-1" }, "locus": { "chromosome": "6", "start_pos": 56568320, "end_pos": 56562098, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076716.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076716.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066787.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066787.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 42, "start_aa": "Thr", "end_pos": 42, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr42", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRT1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 196, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRT1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRT1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRT1" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 74, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 42 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRU4-1", "uniprot_ac": "A0A5G2QRU4", "uniprot_id": "A0A5G2QRU4_PIG", "mass": { "chemical_mass": 44880.0, "monoisotopic_mass": 44880.0 }, "refseq": { "ac": "XP_020936562", "name": "heat shock transcription factor, Y-linked-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936562" }, "gene_names": [ { "name": "LOC110257899", "type": "synonym", "evidence": [ { "id": "XP_020936562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936562" } ] } ], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QRU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRU4/entry#names_and_taxonomy" } ] }, { "name": "heat shock transcription factor, Y-linked-like", "type": "synonym", "evidence": [ { "id": "XP_020936562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936562" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRU4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRU4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRU4", "locus": {} } ], "crossref": [ { "id": "A0A5G2QRU4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRU4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000051413", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000051413", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110257899", "url": "https://www.ncbi.nlm.nih.gov/gene/110257899", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110257899", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257899", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTSQNHI", "url": "https://omabrowser.org/oma/group/CTSQNHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QRU4", "url": "https://www.orthodb.org/?gene=A0A5G2QRU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020936562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936562", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QRU4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQVEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFNRGCPHLLVRMKRRVRMKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHVVNFITTTTSISQYRCISNFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2QRU4-1|A0A5G2QRU4_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRU4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRU4/entry#A0A5G2QRU4-1", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQVEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFNRGCPHLLVRMKRRVRMKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHVVNFITTTTSISQYRCISNFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2QRU4-1|A0A5G2QRU4_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRU4-1" }, "locus": { "chromosome": "Y", "start_pos": 21380551, "end_pos": 21378923, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071770.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071770.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066807.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066807.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "ssc:110257899", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257899", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRU4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRU4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRU4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRU4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRU4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRU4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRU4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRU4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRU4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRU4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRU4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRU4" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2QRV4-1", "uniprot_ac": "A0A5G2QRV4", "uniprot_id": "A0A5G2QRV4_PIG", "mass": { "chemical_mass": 84943.0, "monoisotopic_mass": 84943.0 }, "refseq": {}, "gene_names": [ { "name": "AFAP1L1", "type": "recommended", "evidence": [ { "id": "A0A5G2QRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4" } ] } ], "protein_names": [ { "name": "Actin filament-associated protein 1-like 1", "type": "recommended", "evidence": [ { "id": "A0A5G2QRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in podosome and invadosome formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4#function" }, { "database": "UniProtKB", "id": "ARBA00002089", "url": "https://www.uniprot.org/uniprotkb/ARBA00002089#function" }, { "database": "UniProtKB", "id": "F1RL95", "url": "https://www.uniprot.org/uniprotkb/F1RL95#function" }, { "database": "UniProtKB", "id": "A0A5G2R5D2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AFAP1L1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4", "locus": { "chromosome": "2", "start_pos": 150510002, "end_pos": 150445126, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014431", "url": "https://www.ensembl.org/id/ENSSSCG00000014431" } ] } } ], "crossref": [ { "id": "A0A5G2QRV4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014431", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014431", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13306", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13306", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13307", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13307", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HSCEVVP", "url": "https://omabrowser.org/oma/group/HSCEVVP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR14338", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14338", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14338:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14338:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QRV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5D2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RL95", "url": "https://www.uniprot.org/uniprotkb/F1RL95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RL95-1", "url": "https://www.uniprot.org/uniprotkb/F1RL95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRGRALEQLLPELTGLLSLLDHEHLSDTALEKKTAVASILQSLQPLPAKEVSYLYLNTADLHCGPSFVESLFEEFDCDLGDLRDAPDDDGQPKGASPQPARSPSLRHAADPPPPLPSRPPPEEFYEEALPLGPGKAPEYVSSHDGCSPAQSIVDGYYEDADSSYPATSVNGELKNSYNDSDAMSSSYESYDEEEEEGKGPRPTHQWPSEEASMHLVRDCRMCAFLLRKKRFGQWAKQLTVLKEDQLLCYKSSKDRQPHLRLALDGCTVVYVPKDGRHKRHELRFSQGATEVLVLALQSREQAEEWLKVIREVSKPAGGAEGADVPRSPVLLCKLDLDKRPSQEKQTSDSDSLGLGDSCSTLGREHGKGKKNSLSELKGSVSKAAGRKITRIISFSKKKALAEALQASAAEEEVPCCGHLNVLVNHGWKERWCRLKGSTLYFHKDRTDLRTHVNAIALRGCEVAPGFGPRHPFAFRILRDRQEVAILEASCSEDMGRWLGLLLVETGSRVTPEALHYDYVDVETLTSIVTVGRSSFLYARSCQDPWPEPRVYDDVPYEKMQDEKPARPSGAQVKRHASSCSEKSHRVDPQVSVKRHASSAHQYKYGKNRAEEDARRYLMEKEKLEKEKETIRTELAALRQEKRQLKEALRDHPGAKIKALEEALGTLEAQCRAKEERRIDLELRLVAVKERLQQSLAGPALGLSVSSRTKSGEAASKPQGSAPEQPLPVNCVSELRKRSPSIVTSNQGRVLQKAKEWERKKT", "length": 762, "header": "tr|A0A5G2QRV4-1|A0A5G2QRV4_PIG Isoform 1 of Actin filament-associated protein 1-like 1 OS=Sus scrofa OX=9823 GN=AFAP1L1 PE=4 SV=1 CANONICAL=A0A5G2QRV4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4/entry#A0A5G2QRV4-1", "sequence": { "sequence": "MDRGRALEQLLPELTGLLSLLDHEHLSDTALEKKTAVASILQSLQPLPAKEVSYLYLNTADLHCGPSFVESLFEEFDCDLGDLRDAPDDDGQPKGASPQPARSPSLRHAADPPPPLPSRPPPEEFYEEALPLGPGKAPEYVSSHDGCSPAQSIVDGYYEDADSSYPATSVNGELKNSYNDSDAMSSSYESYDEEEEEGKGPRPTHQWPSEEASMHLVRDCRMCAFLLRKKRFGQWAKQLTVLKEDQLLCYKSSKDRQPHLRLALDGCTVVYVPKDGRHKRHELRFSQGATEVLVLALQSREQAEEWLKVIREVSKPAGGAEGADVPRSPVLLCKLDLDKRPSQEKQTSDSDSLGLGDSCSTLGREHGKGKKNSLSELKGSVSKAAGRKITRIISFSKKKALAEALQASAAEEEVPCCGHLNVLVNHGWKERWCRLKGSTLYFHKDRTDLRTHVNAIALRGCEVAPGFGPRHPFAFRILRDRQEVAILEASCSEDMGRWLGLLLVETGSRVTPEALHYDYVDVETLTSIVTVGRSSFLYARSCQDPWPEPRVYDDVPYEKMQDEKPARPSGAQVKRHASSCSEKSHRVDPQVSVKRHASSAHQYKYGKNRAEEDARRYLMEKEKLEKEKETIRTELAALRQEKRQLKEALRDHPGAKIKALEEALGTLEAQCRAKEERRIDLELRLVAVKERLQQSLAGPALGLSVSSRTKSGEAASKPQGSAPEQPLPVNCVSELRKRSPSIVTSNQGRVLQKAKEWERKKT", "length": 762, "header": "tr|A0A5G2QRV4-1|A0A5G2QRV4_PIG Isoform 1 of Actin filament-associated protein 1-like 1 OS=Sus scrofa OX=9823 GN=AFAP1L1 PE=4 SV=1 CANONICAL=A0A5G2QRV4-1" }, "locus": { "chromosome": "2", "start_pos": 150507286, "end_pos": 150445234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083150.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083150.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066822.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066822.1" } ] } }, { "isoform_ac": "A0A5G2R5D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4/entry#A0A5G2R5D2-1", "sequence": { "sequence": "RVSSSALEQLLPELTGLLSLLDHEHLSDTALEKKTAVASILQSLQPLPAKEVSYLYLNTADLHCGPSFVESLFEEFDCDLGDLRDAPDDDGQPKGASPQPARSPSLRHAADPPPPLPSRPPPEEFYEEALPLGPGKAPEYVSSHDGCSPAQSIVDGYYEDADSSYPATSVNGELKNSYNDSDAMSSSYESYDEEEEEGKGPRPTHQWPSEEASMHLVRDCRMCAFLLRKKRFGQWAKQLTVLKEDQLLCYKSSKDRQPHLRLALDGCTVVYVPKDGRHKRHELRFSQGATEVLVLALQSREQAEEWLKVIREVSKPAGGAEGADVPRSPVLLCKLDLDKRPSQEKQTSDSDSLGLGDSCSTLGREHGKGKKNSLSELKGSVSKAAGRKITRIISFSKKKALAEALQASAAEEEVPCCGHLNVLVNHGWKERWCRLKGSTLYFHKDRTDLRTHVNAIALRGCEVAPGFGPRHPFAFRILRDRQEVAILEASCSEDMGRWLGLLLVETGSRVTPEALHYDYVDVETLTSIVTVGRSSFLYARSCQDPWPEPRVYDDVPYEKMQDEKPARPSGAQVKRHASSCSEKSHRVDPQVSVKRHASSAHQYKYGKNRAEEDARRYLMEKEKLEKEKETIRTELAALRQEKRQLKEALRDHPGAKIKALEEALGTLEAQCRAKEERRIDLELRLVAVKERLQQSLGGPALGLSVSSRTKSGEAASKPQGSAPEQPLPVNCVSELRKRSPSIVTSNQGRVLQKAKEWERKKT", "length": 762, "header": "tr|A0A5G2R5D2-1|A0A5G2R5D2_PIG Computationally mapped isoform of Actin filament-associated protein 1-like 1 OS=Sus scrofa OX=9823 GN=AFAP1L1 PE=4 SV=1 CANONICAL=A0A5G2QRV4-1" }, "locus": { "chromosome": "2", "start_pos": 150507286, "end_pos": 150471170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073988.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073988.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071529.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071529.1" } ] } }, { "isoform_ac": "F1RL95-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4/entry#F1RL95-1", "sequence": { "sequence": "MDRGRALEQLLPELTGLLSLLDHEHLSDTALEKKTAVASILQSLQPLPAKEVSYLYLNTADLHCGPSFVESLFEEFDCDLGDLRDAPDDDGQPKGASPQPARSPSLRHAADPPPPLPSRPPPEEFYEEALPLGPGKAPEYVSSHDGCSPAQSIVDGYYEDADSSYPATSVNGELKNSYNDSDAMSSSYESYDEEEEEGKGPRPTHQWPSEEASMHLVRDCRMCAFLLRKKRFGQWAKQLTVLKEDQLLCYKSSKDRQPHLRLALDGCTVVYVPKDGRHKRHELRFSQGATEVLVLALQSREQAEEWLKVIREVSKPAGGAEGADVPRSPVLLCKLDLDKRPSQEKQTSDSDSLGLGDSCSTLGREHGKGKKNSLSELKGSVSKAAGRKITRIISFSKKKALAEALQASAAEEEVPCCGHLNVLVNHGWKERWCRLKGSTLYFHKDRTDLRTHVNAIALRGCEVAPGFGPRHPFAFRILRDRQEVAILEASCSEDMGRWLGLLLVETGSRVTPEALHYDYVDVETLTSIVTVGRSSFLYARSCQDPWPEPRVYDDVPYEKMQDEKPARPSGAQVKRHASSCSEKSHRVDPQVSVKRHASSAHQYKYGKNRAEEDARRYLMEKEKLEKEKETIRTELAALRQEKRQLKEALRDHPGAKIKALEEALGTLEAQCRAKEERRIDLELRLVAVKERLQQSLAGPALGLSVSSRTKSGEWERKKT", "length": 719, "header": "tr|F1RL95-1|A0A5G2QRV4_PIG Computationally mapped isoform of Actin filament-associated protein 1-like 1 OS=Sus scrofa OX=9823 GN=AFAP1L1 PE=4 SV=4 CANONICAL=A0A5G2QRV4-1" }, "locus": { "chromosome": "2", "start_pos": 150507286, "end_pos": 150445234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015776.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015776.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015360.4", "url": "https://www.ensembl.org/id/ENSSSCP00000015360.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RL95", "url": "https://www.uniprot.org/uniprotkb/F1RL95" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4AB98-1", "protein_name": "Actin filament-associated protein 1-like 1", "gene_name": "Afap1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRSRVLEQLIPELTRLLSLLDHEYLSDSTLEKKMAVASLLQSLQPLPAKEVSFLYVNTADLHSGPSFVESLFEEFDCDLGDLRDMSDDGERSKEASPEPIKSPSLRSTADVPPPLPNKPPPEDYYEEALPLGPGKSPEYISSHNGCSPAQSIVDGYYEDADSSYPTTRMNGESKSSYNDSDAMSSSYESYDEEEEEEKGRQPKHQWPSEEASMHLVRDCRICAFLLRKKRFGQWAKQLTVIKEEQLLCYKSSKDRQPHLRLPLDVCTVVYVPKDSRHKRHELRFSQGATEVLVLALQSREQAEEWLKVIREVSRPIGGAESLEVPRSPVILCKLDQDKRLSQEKQNSDSDSLGMNDSSSTLSRREACEHGKGKKNSLAELKDSMSRAAGRKITRIISFSKKKALSEDLQTFSSEDEAPCCGYLNVLVNHGWKERWCRLRCNTLYFHKDRTDLHTHVNAIALRGCEVAPGFGPRHPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSKVTPEALHYDYVDVETLTSIVSAGRNSFLYAQSCQDQWPEPRIYDEVPYEKVQDEEPQRPTGAQVKRHASSCSEKSHRADPQVKVKRHASSANQYKYGKNRAEEDARRYLVEKERLEKEKETIRTELTALRQEKKELKEAIRNNPGAKLKALEEAVATLDAQCRAKEEQRIDLELKLVAVKERLQQSLAGGPALGLSVSSKSKSQETTNKPQSSVPEQSLPVNCVSEMRKRSPSIVTSNQGRVLQKAKEWEMKKT", "length": 767 }, "evidence": [ { "id": "A0A5G2QRV4", "url": "https://omabrowser.org/oma/group/A0A5G2QRV4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BZI0-1", "protein_name": "Actin filament-associated protein 1-like 1", "gene_name": "Afap1l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRSRVLEQLIPELTGLLSLLDHEYLSDSTLEKKMAVASLLQSLQPLPAKEVSFLYVNTADLHSGPSFVESLFEEFDCDLGDLRDMSDDGEPSKGASPEPTKSPSLRSAAADVPPPLPNKPPPEDYYEEALPLGPGKSPEYISSHNGCSPAQSIVDGYYEDADNSYPTTRMNGELKNSYNDSDAMSSSYESYDEEEEEEKGRQPKHQWPSEEASMHLVRDCRICAFLLRKKRFGQWAKQLTVIKEEQLLCYKSSKDRQPHLRLALDVCTVIYVPKDSRHKRHELRFSQGATEVLVLALQSREQAEEWLKVIREVSRPIVGAEGLEVPRSPVILCKADQDKRLSQEKQNSDSDSLGMNDSGSTLGRREACEHGKGKKNSLAELKGSMSRAAGRKITRIISFSKKKALSEDLQTFSSEDEVPCCGYLNVLVNQGWKERWCRLRCNTLYFHKDRTDLHTHVNSIALRGCEVAPGFGPRHPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSKVTPEALHYDYVDVETLTSIVSAGRNSFLYAQSCQDQWPEPRIYDEVPYEKVQDEEPQRPTGAQVKRHASSCSEKSHRADPQVKVKRHASSANQYKYGKNRAEEDARRYLVEKERLEKEKETIRTELTALRQEKKELKEAIRNNPGAKSKALEEAVATLEAQCRAKEEQRIDLELKLVAVKERLQQSLAGGPALGLSVSNKNKSQDTTNKPQSNAPEQSLPVNCVSELRKRSPSIVTSNQGRVLQKAKEWEMKKT", "length": 768 }, "evidence": [ { "id": "A0A5G2QRV4", "url": "https://omabrowser.org/oma/group/A0A5G2QRV4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TED9-1", "protein_name": "Actin filament-associated protein 1-like 1", "gene_name": "AFAP1L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTADLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNKPPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYNDSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQLTVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQSREQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNCSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVPCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNSFLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT", "length": 768 }, "evidence": [ { "id": "A0A5G2QRV4", "url": "https://omabrowser.org/oma/group/A0A5G2QRV4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4" } ], "pmid": "" }, { "name": "podosome", "id": "GO:0002102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002102", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRV4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 762, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRV4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRV4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRV4" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 219, "end_pos": 315, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRW3-1", "uniprot_ac": "A0A5G2QRW3", "uniprot_id": "A0A5G2QRW3_PIG", "mass": { "chemical_mass": 26114.0, "monoisotopic_mass": 26114.0 }, "refseq": {}, "gene_names": [ { "name": "HBB", "type": "recommended", "evidence": [ { "id": "A0A5G2QRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" } ] } ], "protein_names": [ { "name": "Hemoglobin, beta", "type": "synonym", "evidence": [ { "id": "A0A5G2QRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HBB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3", "locus": { "chromosome": "9", "start_pos": 4800293, "end_pos": 4802364, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014725", "url": "https://www.ensembl.org/id/ENSSSCG00000014725" } ] } } ], "crossref": [ { "id": "A0A5G2QRW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014725", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014725", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08925", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08925", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11442", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11442", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11442:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11442:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00042", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00042", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1237044", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1237044", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1247673", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1247673", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2168880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9707564", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9707564", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9707616", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9707616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QRW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLVALCTVRMGPRAPQRRAEGLKLVPGTPKTGILSTFKPHPVEPRPGLGQSAPRSREGRRLGGHKRKSRASSHLHLLLTQPCSLATAQTDNMVHLSAEEKEAVLGLWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSNADAVMGNPKVKAHGKKVLQSFSDGLKHLDNLKGTFAKLSELHCDQLHVDPENFRLLGNVIVVVLARRLGHDFNPDVQAAFQKVVAGVANALAHKYH", "length": 239, "header": "tr|A0A5G2QRW3-1|A0A5G2QRW3_PIG Isoform 1 of Hemoglobin, beta OS=Sus scrofa OX=9823 GN=HBB PE=1 SV=1 CANONICAL=A0A5G2QRW3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3/entry#A0A5G2QRW3-1", "sequence": { "sequence": "MKLVALCTVRMGPRAPQRRAEGLKLVPGTPKTGILSTFKPHPVEPRPGLGQSAPRSREGRRLGGHKRKSRASSHLHLLLTQPCSLATAQTDNMVHLSAEEKEAVLGLWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSNADAVMGNPKVKAHGKKVLQSFSDGLKHLDNLKGTFAKLSELHCDQLHVDPENFRLLGNVIVVVLARRLGHDFNPDVQAAFQKVVAGVANALAHKYH", "length": 239, "header": "tr|A0A5G2QRW3-1|A0A5G2QRW3_PIG Isoform 1 of Hemoglobin, beta OS=Sus scrofa OX=9823 GN=HBB PE=1 SV=1 CANONICAL=A0A5G2QRW3-1" }, "locus": { "chromosome": "9", "start_pos": 4802165, "end_pos": 4800686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081549.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081549.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067521.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067521.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1237044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1237044", "resource": "Reactome", "description": "Erythrocytes take up carbon dioxide and release oxygen" }, { "id": "R-SSC-1247673", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1247673", "resource": "Reactome", "description": "Erythrocytes take up oxygen and release carbon dioxide" }, { "id": "R-SSC-2168880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2168880", "resource": "Reactome", "description": "Scavenging of heme from plasma" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-9707564", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9707564", "resource": "Reactome", "description": "Cytoprotection by HMOX1" }, { "id": "R-SSC-9707616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9707616", "resource": "Reactome", "description": "Heme signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" } ], "pmid": "" }, { "name": "hemoglobin alpha binding", "id": "GO:0031721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031721", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" } ], "pmid": "" }, { "name": "oxygen binding", "id": "GO:0019825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019825", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" } ], "pmid": "" }, { "name": "oxygen carrier activity", "id": "GO:0005344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005344", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "hemoglobin complex", "id": "GO:0005833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005833", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" } ], "pmid": "" }, { "name": "haptoglobin-hemoglobin complex", "id": "GO:0031838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031838", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "erythrocyte development", "id": "GO:0048821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048821", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" } ], "pmid": "" }, { "name": "oxygen transport", "id": "GO:0015671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015671", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRW3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 239, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRW3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRW3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRW3" }, { "id": "PS01033", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Globin", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 239, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRY2-1", "uniprot_ac": "A0A5G2QRY2", "uniprot_id": "A0A5G2QRY2_PIG", "mass": { "chemical_mass": 72135.0, "monoisotopic_mass": 72135.0 }, "refseq": {}, "gene_names": [ { "name": "MAG", "type": "recommended", "evidence": [ { "id": "A0A5G2QRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ] } ], "protein_names": [ { "name": "Myelin-associated glycoprotein", "type": "recommended", "evidence": [ { "id": "A0A5G2QRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MAG", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2", "locus": { "chromosome": "6", "start_pos": 44809926, "end_pos": 44794204, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002887", "url": "https://www.ensembl.org/id/ENSSSCG00000002887" } ] } } ], "crossref": [ { "id": "A0A5G2QRY2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002887", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002887", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05712", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05712", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20987", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20987", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12035", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12035", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12035:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12035:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-193634", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RM75", "url": "https://www.uniprot.org/uniprotkb/F1RM75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RM75-1", "url": "https://www.uniprot.org/uniprotkb/F1RM75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGWLADSFQWGQKTFPTQGDGAVAHLLYKMIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIINTPSIVVPPEVVAGTEVEVSCMVPDNCPELHPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQSFPNTSLQFEGYASLNVKYPPVIVEVNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGAVLQEAVAESLSLELDEVTPAEDGVYACLAENAYGQDNRTVELSVMYAPWKPTVNGTVVAVEGETVSILCSTQSNPDPIITIFKEKQILATVIYESELQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPVILLESHCAAARDTVQCLCVVKANPEPTVAFELPSRNVTVNETEREFVYSERSGLLLSSILTLRGQAQAPPRVICTSRNLYGTKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSAGDTPPVLFSSDFRISGAPEKYESERRLGSERRLLGLRGEPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK", "length": 654, "header": "tr|A0A5G2QRY2-1|A0A5G2QRY2_PIG Isoform 1 of Myelin-associated glycoprotein OS=Sus scrofa OX=9823 GN=MAG PE=1 SV=2 CANONICAL=A0A5G2QRY2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2/entry#A0A5G2QRY2-1", "sequence": { "sequence": "MGWLADSFQWGQKTFPTQGDGAVAHLLYKMIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIINTPSIVVPPEVVAGTEVEVSCMVPDNCPELHPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQSFPNTSLQFEGYASLNVKYPPVIVEVNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGAVLQEAVAESLSLELDEVTPAEDGVYACLAENAYGQDNRTVELSVMYAPWKPTVNGTVVAVEGETVSILCSTQSNPDPIITIFKEKQILATVIYESELQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPVILLESHCAAARDTVQCLCVVKANPEPTVAFELPSRNVTVNETEREFVYSERSGLLLSSILTLRGQAQAPPRVICTSRNLYGTKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSAGDTPPVLFSSDFRISGAPEKYESERRLGSERRLLGLRGEPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK", "length": 654, "header": "tr|A0A5G2QRY2-1|A0A5G2QRY2_PIG Isoform 1 of Myelin-associated glycoprotein OS=Sus scrofa OX=9823 GN=MAG PE=1 SV=2 CANONICAL=A0A5G2QRY2-1" }, "locus": { "chromosome": "6", "start_pos": 44809566, "end_pos": 44795941, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071510.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071510.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067670.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067670.2" } ] } }, { "isoform_ac": "F1RM75-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2/entry#F1RM75-1", "sequence": { "sequence": "MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIINTPSIVVPPEVVAGTEVEVSCMVPDNCPELHPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQSFPNTSLQFEGYASLNVKYPPVIVEVNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGAVLQEAVAESLSLELDEVTPAEDGVYACLAENAYGQDNRTVELSVMYAPWKPTVNGTVVAVEGETVSILCSTQSNPDPIITIFKEKQILATVIYESELQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPVILLESHCAAARDTVQCLCVVKANPEPTVAFELPSRNVTVNETEREFVYSERSGLLLSSILTLRGQAQAPPRVICTSRNLYGTKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSAGDTPPVLFSSDFRISGAPEKYESREVSTLE", "length": 579, "header": "tr|F1RM75-1|A0A5G2QRY2_PIG Computationally mapped isoform of Myelin-associated glycoprotein OS=Sus scrofa OX=9823 GN=MAG PE=1 SV=4 CANONICAL=A0A5G2QRY2-1" }, "locus": { "chromosome": "6", "start_pos": 44808435, "end_pos": 44796651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003190.4", "url": "https://www.ensembl.org/id/ENSSSCT00000003190.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003109.4", "url": "https://www.ensembl.org/id/ENSSSCP00000003109.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 469, "start_aa": "Thr", "end_pos": 469, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr469", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 581, "start_aa": "Thr", "end_pos": 581, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr581", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RM75", "url": "https://www.uniprot.org/uniprotkb/F1RM75" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-193634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193634", "resource": "Reactome", "description": "Axonal growth inhibition (RHOA activation)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "central nervous system myelin formation", "id": "GO:0032289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032289", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "positive regulation of myelination", "id": "GO:0031643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031643", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "myelin sheath adaxonal region", "id": "GO:0035749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035749", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "Schmidt-Lanterman incisure", "id": "GO:0043220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043220", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "paranode region of axon", "id": "GO:0033270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "compact myelin", "id": "GO:0043218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043218", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "sialic acid binding", "id": "GO:0033691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033691", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "ganglioside GT1b binding", "id": "GO:1905576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRY2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRY2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 654, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRY2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRY2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRY2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 268, "end_pos": 349, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 469, 581 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 135, "end_pos": 137 }, { "start_pos": 251, "end_pos": 253 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 569, "end_pos": 571 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRZ0-1", "uniprot_ac": "A0A5G2QRZ0", "uniprot_id": "A0A5G2QRZ0_PIG", "mass": { "chemical_mass": 35394.0, "monoisotopic_mass": 35394.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QRZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0", "locus": {} } ], "crossref": [ { "id": "A0A5G2QRZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CTETEMP", "url": "https://omabrowser.org/oma/group/CTETEMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QRZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRNITGVSGLLLLGFSEEADMHPLIFGLFLSMYLITVFGNLLLILAVSSDSCLHTPMYFFLSNLSFVDICFISTTIPKMLQNICSKRQVITYAGCITQMYFFILFVGLDALLLTVMAYDRFVAICHPLHYMVIMNPQICRILVMASWITSVLDSLLQTLMTLRLSFCRNVKLPHYFCELRQLIQLACSDKCLNNMVMNFAAGLLGGIPLAGILYSYYKIVASIRGISSAEGKYKAFSTCASHLSGVSLFFSTSLGIYLSSSATHSSYLIEINSVMYTVVTPMLNPFIYSLRNKHIKRSLKAFFHMAAIRSPVDLG", "length": 317, "header": "tr|A0A5G2QRZ0-1|A0A5G2QRZ0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRZ0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0/entry#A0A5G2QRZ0-1", "sequence": { "sequence": "MAPRNITGVSGLLLLGFSEEADMHPLIFGLFLSMYLITVFGNLLLILAVSSDSCLHTPMYFFLSNLSFVDICFISTTIPKMLQNICSKRQVITYAGCITQMYFFILFVGLDALLLTVMAYDRFVAICHPLHYMVIMNPQICRILVMASWITSVLDSLLQTLMTLRLSFCRNVKLPHYFCELRQLIQLACSDKCLNNMVMNFAAGLLGGIPLAGILYSYYKIVASIRGISSAEGKYKAFSTCASHLSGVSLFFSTSLGIYLSSSATHSSYLIEINSVMYTVVTPMLNPFIYSLRNKHIKRSLKAFFHMAAIRSPVDLG", "length": 317, "header": "tr|A0A5G2QRZ0-1|A0A5G2QRZ0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QRZ0-1" }, "locus": { "chromosome": "2", "start_pos": 64120025, "end_pos": 64119075, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090629.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090629.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067680.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067680.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRZ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 317, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRZ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRZ0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QRZ6-1", "uniprot_ac": "A0A5G2QRZ6", "uniprot_id": "A0A5G2QRZ6_PIG", "mass": { "chemical_mass": 97062.0, "monoisotopic_mass": 97062.0 }, "refseq": {}, "gene_names": [ { "name": "TLR5", "type": "recommended", "evidence": [ { "id": "A0A5G2QRZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ] } ], "protein_names": [ { "name": "Toll-like receptor 5", "type": "recommended", "evidence": [ { "id": "A0A5G2QRZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response. Recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota. Upon ligand binding such as bacterial flagellins, recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion and induction of the inflammatory response. Plays thereby an important role in the relationship between the intestinal epithelium and enteric microbes and contributes to the gut microbiota composition throughout life.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6#function" }, { "database": "UniProtKB", "id": "ARBA00057507", "url": "https://www.uniprot.org/uniprotkb/ARBA00057507#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TLR5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6", "locus": { "chromosome": "10", "start_pos": 19387666, "end_pos": 19410024, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010885", "url": "https://www.ensembl.org/id/ENSSSCG00000010885" } ] } } ], "crossref": [ { "id": "A0A5G2QRZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010885", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010885", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24365", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24365", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24365:SF525", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24365:SF525", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01582", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDCLVLLLTLLVASPALGMPSCFFDGQRAIYRGCNLTQVPQVPSGTKSLLLSFNYIRTVTAGSFPFLEGLQLLELGTQLTPLSIDREAFRNLPNLRILDLGHSQIAFLHPDAFQELPHSELRLFSCGLSDAILKDGYFRNLASLTRLDLSKNQIQSLHLHPSFQELNSLKAIDLSLNQIPLVCEQGLKPLQGKTLSFLSLADNNLYSRVSVDWGKCMNPFRNMALEMLDVSGNGWTADTTRNFSQAVNGSQISSLVLAHHIMGSGFGFHNIKDPDHHTFASLGRSSLIQLDLSHGFIFSLNFRLFGTLKELKVLNLAFNKINKIADQAFHGLDNLQILNMSYNLLGELYNSNFEGLPKLAYIDLQKNHIGIIQDQTFRFLKKLNTLDLRDNALKTIQFIPSIPTLFLGGNKLVTLPNIRLTANFIHLSENRLENLDNLYFLLQVPHLQILILNQNRFSNCNQRHAPSENPSLEQLFLGENMLQLAWEAGFCWDVFKGLSHLQVLYLNNNYLNFLPPGVFRHLTALRGLSLSYNRLTVLYPGDLPAHLEVLDLSRNQLLSPDPDLFTSLSAVDLSHNKFVCDCELSTFINWLNQTNVTIFGSRDDIYCMYPSSLAGSPLNTVSMAGCSEEEVLESLKFSLFILFTVTLTLLFVAILVVMKFRGFCFICYKKVQRLVFKDPSLGRESDTYKYDAYLCFSGKDFEWVQEALLKNLDAQYSDQNRLNLCFEERDFVPGEDRISNIQDAVWSSRKVVCLVSRHFLRDGWCLEAFSYAQSRCLADLNGTLIMVVVGSLPQYQLMKHQSIRGFVRKQQYLRWPEDLQDVSWFLNKLSQYILKKVKEKKKDSDIQLQSVTIS", "length": 855, "header": "tr|A0A5G2QRZ6-1|A0A5G2QRZ6_PIG Isoform 1 of Toll-like receptor 5 OS=Sus scrofa OX=9823 GN=TLR5 PE=3 SV=1 CANONICAL=A0A5G2QRZ6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6/entry#A0A5G2QRZ6-1", "sequence": { "sequence": "MGDCLVLLLTLLVASPALGMPSCFFDGQRAIYRGCNLTQVPQVPSGTKSLLLSFNYIRTVTAGSFPFLEGLQLLELGTQLTPLSIDREAFRNLPNLRILDLGHSQIAFLHPDAFQELPHSELRLFSCGLSDAILKDGYFRNLASLTRLDLSKNQIQSLHLHPSFQELNSLKAIDLSLNQIPLVCEQGLKPLQGKTLSFLSLADNNLYSRVSVDWGKCMNPFRNMALEMLDVSGNGWTADTTRNFSQAVNGSQISSLVLAHHIMGSGFGFHNIKDPDHHTFASLGRSSLIQLDLSHGFIFSLNFRLFGTLKELKVLNLAFNKINKIADQAFHGLDNLQILNMSYNLLGELYNSNFEGLPKLAYIDLQKNHIGIIQDQTFRFLKKLNTLDLRDNALKTIQFIPSIPTLFLGGNKLVTLPNIRLTANFIHLSENRLENLDNLYFLLQVPHLQILILNQNRFSNCNQRHAPSENPSLEQLFLGENMLQLAWEAGFCWDVFKGLSHLQVLYLNNNYLNFLPPGVFRHLTALRGLSLSYNRLTVLYPGDLPAHLEVLDLSRNQLLSPDPDLFTSLSAVDLSHNKFVCDCELSTFINWLNQTNVTIFGSRDDIYCMYPSSLAGSPLNTVSMAGCSEEEVLESLKFSLFILFTVTLTLLFVAILVVMKFRGFCFICYKKVQRLVFKDPSLGRESDTYKYDAYLCFSGKDFEWVQEALLKNLDAQYSDQNRLNLCFEERDFVPGEDRISNIQDAVWSSRKVVCLVSRHFLRDGWCLEAFSYAQSRCLADLNGTLIMVVVGSLPQYQLMKHQSIRGFVRKQQYLRWPEDLQDVSWFLNKLSQYILKKVKEKKKDSDIQLQSVTIS", "length": 855, "header": "tr|A0A5G2QRZ6-1|A0A5G2QRZ6_PIG Isoform 1 of Toll-like receptor 5 OS=Sus scrofa OX=9823 GN=TLR5 PE=3 SV=1 CANONICAL=A0A5G2QRZ6-1" }, "locus": { "chromosome": "10", "start_pos": 19392774, "end_pos": 19390208, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033032.3", "url": "https://www.ensembl.org/id/ENSSSCT00000033032.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061007.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061007.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ], "pmid": "" }, { "name": "interleukin-1 receptor binding", "id": "GO:0005149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005149", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ], "pmid": "" }, { "name": "cellular response to mechanical stimulus", "id": "GO:0071260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071260", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ], "pmid": "" }, { "name": "toll-like receptor signaling pathway", "id": "GO:0002224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002224", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ], "pmid": "" }, { "name": "toll-like receptor 5 signaling pathway", "id": "GO:0034146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034146", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 782, "end_pos": 784, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QRZ6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 855, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QRZ6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QRZ6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QRZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRZ6" }, { "id": "PS50104", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50104" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TIR", "eco_id": "ECO_0000259", "start_pos": 689, "end_pos": 834, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 782, "end_pos": 784 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QS30-1", "uniprot_ac": "A0A5G2QS30", "uniprot_id": "A0A5G2QS30_PIG", "mass": { "chemical_mass": 142512.0, "monoisotopic_mass": 142512.0 }, "refseq": {}, "gene_names": [ { "name": "ADGRA2", "type": "recommended", "evidence": [ { "id": "A0A5G2QS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ] } ], "protein_names": [ { "name": "Adhesion G protein-coupled receptor A2", "type": "recommended", "evidence": [ { "id": "A0A5G2QS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 124", "type": "synonym", "evidence": [ { "id": "A0A5G2QS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30/entry#names_and_taxonomy" } ] }, { "name": "Tumor endothelial marker 5", "type": "synonym", "evidence": [ { "id": "A0A5G2QS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Endothelial receptor which functions together with RECK to enable brain endothelial cells to selectively respond to Wnt7 signals (WNT7A or WNT7B). Plays a key role in Wnt7-specific responses, such as endothelial cell sprouting and migration in the forebrain and neural tube, and establishment of the blood-brain barrier. Acts as a Wnt7-specific coactivator of canonical Wnt signaling: required to deliver RECK-bound Wnt7 to frizzled by assembling a higher-order RECK-ADGRA2-Fzd-LRP5-LRP6 complex. ADGRA2-tethering function does not rely on its G-protein coupled receptor (GPCR) structure but instead on its combined capacity to interact with RECK extracellularly and recruit the Dishevelled scaffolding protein intracellularly. Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30#function" }, { "database": "UniProtKB", "id": "ARBA00053609", "url": "https://www.uniprot.org/uniprotkb/ARBA00053609#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ADGRA2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30", "locus": { "chromosome": "15", "start_pos": 48573197, "end_pos": 48610668, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015825", "url": "https://www.ensembl.org/id/ENSSSCG00000015825" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015825", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015825", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15998", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15998", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45930", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45930", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45930:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45930:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS30-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDX1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTAGRRMRAAPARLLLQLLPWLLLLVPGTWGAPGCPVPIRSCKCSGERPKGLSGGSSNPARRRVVCGGGDLPEPPEPGLLPNSTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNVISTVQPGAFLGLGELKRLDLSNNRIGCLSSETFQGIPKLLRLNISGNIFSRLQPGVFDELPALKVVDFGTEFLTCDCRLHWLLPWARNRSLQLSERTLCAYPSALRAQALGGLQEAQLRCEGALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNQAPVEGDEQAGILLADSLIHDCTFITSELTVSHIGVWASGEWECSVSTVQGNASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLSGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSGIVGALERIGGAALSPHAQHISVNSRNVALEAYLIKPHSYVGLCTAFQRREAGAPGARPEGPGQNPSPELEPLADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSSLPAALTPPVPPDCTLQLLVFRNGRLFRSHGNTSRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAAWWSQEGPGGPGGWSSEGCQLRSSQPNVSSLHCQHLGNVAVLMELSTFPREVGGSGAGLHPVVYPCTALLLLCLFSTIITYILNHSSIHVSRKGWHMLLNLCFHMAMTSAVFAGGITLTNYQIVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDAAVPAPRPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQSPKGGTSRVPLEPGEELRGSTRLRSSGPLLSDSGSLLAAGSAGVATPGPPEDGDGLYSPGVQLGALVTTHFLYLAMWACGALTVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPASASRASPRAAPAAAEDGSPMFGEGPASLKSSPSSSSGHAPPPGPCKLTNLQLAQSQACEAGSAVRGEGEPEPPGPRGALGPRHPNNLHHGRRGHKSRAKGHRAGEAGGKNRLRALRGGAAGAAELQSSESGSLHNSPSDSYPGSGRNSPGAGPRPEGEPMLTPSEGSDTSAAPLSEPGRPGQRRCSSRDNLKGGGAGALEKESKRRSYPLNTASLNGAPKGGKYDDITLTGTEAAGSGCMKTGLWKSETTV", "length": 1336, "header": "tr|A0A5G2QS30-1|A0A5G2QS30_PIG Isoform 1 of Adhesion G protein-coupled receptor A2 OS=Sus scrofa OX=9823 GN=ADGRA2 PE=1 SV=2 CANONICAL=A0A5G2QS30-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QS30-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30/entry#A0A5G2QS30-1", "sequence": { "sequence": "MGTAGRRMRAAPARLLLQLLPWLLLLVPGTWGAPGCPVPIRSCKCSGERPKGLSGGSSNPARRRVVCGGGDLPEPPEPGLLPNSTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNVISTVQPGAFLGLGELKRLDLSNNRIGCLSSETFQGIPKLLRLNISGNIFSRLQPGVFDELPALKVVDFGTEFLTCDCRLHWLLPWARNRSLQLSERTLCAYPSALRAQALGGLQEAQLRCEGALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNQAPVEGDEQAGILLADSLIHDCTFITSELTVSHIGVWASGEWECSVSTVQGNASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLSGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSGIVGALERIGGAALSPHAQHISVNSRNVALEAYLIKPHSYVGLCTAFQRREAGAPGARPEGPGQNPSPELEPLADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSSLPAALTPPVPPDCTLQLLVFRNGRLFRSHGNTSRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAAWWSQEGPGGPGGWSSEGCQLRSSQPNVSSLHCQHLGNVAVLMELSTFPREVGGSGAGLHPVVYPCTALLLLCLFSTIITYILNHSSIHVSRKGWHMLLNLCFHMAMTSAVFAGGITLTNYQIVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDAAVPAPRPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQSPKGGTSRVPLEPGEELRGSTRLRSSGPLLSDSGSLLAAGSAGVATPGPPEDGDGLYSPGVQLGALVTTHFLYLAMWACGALTVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPASASRASPRAAPAAAEDGSPMFGEGPASLKSSPSSSSGHAPPPGPCKLTNLQLAQSQACEAGSAVRGEGEPEPPGPRGALGPRHPNNLHHGRRGHKSRAKGHRAGEAGGKNRLRALRGGAAGAAELQSSESGSLHNSPSDSYPGSGRNSPGAGPRPEGEPMLTPSEGSDTSAAPLSEPGRPGQRRCSSRDNLKGGGAGALEKESKRRSYPLNTASLNGAPKGGKYDDITLTGTEAAGSGCMKTGLWKSETTV", "length": 1336, "header": "tr|A0A5G2QS30-1|A0A5G2QS30_PIG Isoform 1 of Adhesion G protein-coupled receptor A2 OS=Sus scrofa OX=9823 GN=ADGRA2 PE=1 SV=2 CANONICAL=A0A5G2QS30-1" }, "locus": { "chromosome": "15", "start_pos": 48610619, "end_pos": 48574574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070661.3", "url": "https://www.ensembl.org/id/ENSSSCT00000070661.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064812.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064812.2" } ] } }, { "isoform_ac": "A0A5G2RDX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30/entry#A0A5G2RDX1-1", "sequence": { "sequence": "MGTAGRRMRAAPARLLLQLLPWLLLLVPGTWGAPGCPVPIRSCKCSGERPKGLSGGSSNPARRRVVCGGGDLPEPPEPGLLPNSTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNVISTVQPGAFLGLGELKRLDLSNNRIGCLSSETFQGIPKLLRLNISGNIFSRLQPGVFDELPALKVVDFGTEFLTCDCRLHWLLPWARNRSLQLSERTLCAYPSALRAQALGGLQEAQLRCEGALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNQAPVEGDEQAGILLADSLIHDCTFITSELTVSHIGVWASGEWECSVSTVQGNASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLSGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSGIVGALERIGGAALSPHAQHISVELSTFPREVGGSGAGLHPVVYPCTALLLLCLFSTIITYILNHSSIHVSRKGWHMLLNLCFHMAMTSAVFAGGITLTNYQIVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDAAVPAPRPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQSPKGGTSRVPLEPGEELRGSTRLRSSGPLLSDSGSLLAAGSAGVATPGPPEDGDGLYSPGVQLGALVTTHFLYLAMWACGALTVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPASASRASPRAAPAAAEDGSPMFGEGPASLKSSPSSSSGHAPPPGPCKLTNLQLAQSQACEAGSAVRGEGEPEPPGPRGALGPRHPNNLHHGRRGHKSRAKGHRAGEAGGKNRLRALRGGAAGAAELQSSESGSLHNSPSDSYPGSGRNSPGAGPRPEGEPMLTPSEGSDTSAAPLSEPGRPGQRRCSSRDNLKGGGAGALEKESKRRSYPLNTASLNGAPKGGKYDDITLTGTEAAGSGCMKTGLWKSETTV", "length": 1120, "header": "tr|A0A5G2RDX1-1|A0A5G2RDX1_PIG Computationally mapped isoform of Adhesion G protein-coupled receptor A2 OS=Sus scrofa OX=9823 GN=ADGRA2 PE=1 SV=1 CANONICAL=A0A5G2QS30-1" }, "locus": { "chromosome": "15", "start_pos": 48610619, "end_pos": 48574574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084353.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084353.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069002.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069002.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1000, "start_aa": "Thr", "end_pos": 1000, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1000", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" }, { "name": "filopodium", "id": "GO:0030175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030175", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" }, { "name": "Wnt signalosome", "id": "GO:1990909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990909", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" }, { "name": "endothelial cell migration", "id": "GO:0043542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043542", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" }, { "name": "regulation of angiogenesis", "id": "GO:0045765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045765", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" }, { "name": "regulation of chemotaxis", "id": "GO:0050920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050920", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 657, "end_pos": 659, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 735, "end_pos": 737, "annotation": "n_glycosylation_sequon" }, { "start_pos": 792, "end_pos": 794, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" }, { "id": "PS50227", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 1", "eco_id": "ECO_0000259", "start_pos": 326, "end_pos": 420, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" }, { "id": "PS50261", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 2", "eco_id": "ECO_0000259", "start_pos": 767, "end_pos": 942, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" }, { "id": "PS50221", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50221" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GAIN-B", "eco_id": "ECO_0000259", "start_pos": 592, "end_pos": 757, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS30" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 259, "end_pos": 343, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1000 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 206, "end_pos": 208 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 335, "end_pos": 337 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 657, "end_pos": 659 }, { "start_pos": 688, "end_pos": 690 }, { "start_pos": 735, "end_pos": 737 }, { "start_pos": 792, "end_pos": 794 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QS76-1", "uniprot_ac": "A0A5G2QS76", "uniprot_id": "A0A5G2QS76_PIG", "mass": { "chemical_mass": 62592.0, "monoisotopic_mass": 62592.0 }, "refseq": { "ac": "XP_020939243", "name": "mediator of RNA polymerase II transcription subunit 26 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939243" }, "gene_names": [ { "name": "MED26", "type": "recommended", "evidence": [ { "id": "A0A5G2QS76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76" } ] }, { "name": "MED26", "type": "synonym", "evidence": [ { "id": "XP_020939243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939243" } ] } ], "protein_names": [ { "name": "Mediator of RNA polymerase II transcription subunit 26", "type": "recommended", "evidence": [ { "id": "A0A5G2QS76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76/entry#names_and_taxonomy" } ] }, { "name": "Cofactor required for Sp1 transcriptional activation subunit 7", "type": "synonym", "evidence": [ { "id": "A0A5G2QS76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76/entry#names_and_taxonomy" } ] }, { "name": "Mediator complex subunit 26", "type": "synonym", "evidence": [ { "id": "A0A5G2QS76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76/entry#names_and_taxonomy" } ] }, { "name": "mediator of RNA polymerase II transcription subunit 26 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_020939243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939243" } ] } ], "function": [ { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.", "evidence": [ { "database": "UniProtKB", "id": "F1S9W1", "url": "https://www.uniprot.org/uniprotkb/F1S9W1#function" }, { "database": "UniProtKB", "id": "ARBA00057523", "url": "https://www.uniprot.org/uniprotkb/ARBA00057523#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS76", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MED26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76", "locus": { "chromosome": "2", "start_pos": 61035655, "end_pos": 60984256, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013862", "url": "https://www.ensembl.org/id/ENSSSCG00000013862" } ] } } ], "crossref": [ { "id": "A0A5G2QS76", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QS76", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013862", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013862", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00183", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00183", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737822", "url": "https://www.ncbi.nlm.nih.gov/gene/100737822", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737822", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737822", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDASRMD", "url": "https://omabrowser.org/oma/group/PDASRMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S9W1", "url": "https://www.orthodb.org/?gene=F1S9W1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15201", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15201", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15201:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15201:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15693", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15693", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15694", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15694", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020939243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939243", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QS76", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS76-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S9W1", "url": "https://www.uniprot.org/uniprotkb/F1S9W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S9W1-1", "url": "https://www.uniprot.org/uniprotkb/F1S9W1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAVQEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVHQNEATLRGLAGATGSANGGAHNCRPEAGAAGPPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDSLVPNLSPLPTNGISGSPESFPGSLDGSGHAGPEGSRLEHSENDKHSGKIPINAVRPHTSSPGLGKPPGPCLQTKAVLLQQLDRVDETPGPPHPKAPPRCSFSPRNSRHEGSFARQRSPYTYKGSVPSPSQRPQSLDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPEGHQRLSGPGCKAGLPPAEPLLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHTEQPRTELDKPEAKANLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARKPHVLVPHGPPTDLPGLSREVTQDDLDRIQAHQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD", "length": 572, "header": "tr|A0A5G2QS76-1|A0A5G2QS76_PIG Isoform 1 of Mediator of RNA polymerase II transcription subunit 26 OS=Sus scrofa OX=9823 GN=MED26 PE=3 SV=1 CANONICAL=A0A5G2QS76-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QS76-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76/entry#A0A5G2QS76-1", "sequence": { "sequence": "MVAVQEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVHQNEATLRGLAGATGSANGGAHNCRPEAGAAGPPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDSLVPNLSPLPTNGISGSPESFPGSLDGSGHAGPEGSRLEHSENDKHSGKIPINAVRPHTSSPGLGKPPGPCLQTKAVLLQQLDRVDETPGPPHPKAPPRCSFSPRNSRHEGSFARQRSPYTYKGSVPSPSQRPQSLDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPEGHQRLSGPGCKAGLPPAEPLLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHTEQPRTELDKPEAKANLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARKPHVLVPHGPPTDLPGLSREVTQDDLDRIQAHQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD", "length": 572, "header": "tr|A0A5G2QS76-1|A0A5G2QS76_PIG Isoform 1 of Mediator of RNA polymerase II transcription subunit 26 OS=Sus scrofa OX=9823 GN=MED26 PE=3 SV=1 CANONICAL=A0A5G2QS76-1" }, "locus": { "chromosome": "2", "start_pos": 61034537, "end_pos": 61032164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075256.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075256.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066974.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066974.1" } ] } }, { "isoform_ac": "F1S9W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76/entry#F1S9W1-1", "sequence": { "sequence": "MTAAPPSPQQIRDRLLQAIDPQSNIRNMVAVQEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVHQNEATLRGLAGATGSANGGAHNCRPEAGAAGPPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDSLVPNLSPLPTNGISGSPESFPGSLDGSGHAGPEGSRLEHSENDKHSGKIPINAVRPHTSSPGLGKPPGPCLQTKAVLLQQLDRVDETPGPPHPKAPPRCSFSPRNSRHEGSFARQRSPYTYKGSVPSPSQRPQSLDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPEGHQRLSGPGCKAGLPPAEPLLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHTEQPRTELDKPEAKANLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARKPHVLVPHGPPTDLPGLSREVTQDDLDRIQAHQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD", "length": 599, "header": "tr|F1S9W1-1|F1S9W1_PIG Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 26 OS=Sus scrofa OX=9823 GN=MED26 PE=3 SV=3 CANONICAL=A0A5G2QS76-1" }, "locus": { "chromosome": "2", "start_pos": 61034537, "end_pos": 60984519, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015141.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015141.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014736.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014736.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS76", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737822", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737822", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AK99-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 26", "gene_name": "MED26", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCPGRKRTNYFCLQGKRGTNEKALLLSHRYSSILGLELKTNINIRLKKNPTTHRCLFPLITLHCSPVCPMLCSVITSSELSLVCVTRRAAAPQALIFGEILMVKIHNMVAVLEVISSLEKYPITKEALEETRLGRLINEVRKKTSNEELAKRAKKLLRNWQKLIEPVTPNEAVPRGLQNPPGSANGGAHNCKPEAPLPAVAGSKPISELKSRNDIQKLNSPKPEKLGNRKRKGEHRDGHQGPPPPKVSKVSHEILQNSSPPPTNGIGGSPESFPSPVDVNLHAGPESSRTELSENDKHNKIPVNAVKPHTSSPGLVKPSSTSSLLKTAVLQQHDKLEETTGSHQPKSPRCSSFSPRNVRHDTFARQHTTYSPKDSMPSPSQRSQFLDTAQVPSPPPSLMQPSTPPMPAKRLEFSQQSVSEVSQHWQEQQVPSDSQHRHTAGTLPQHTSPSCKTSSHPGESLMSHIGFSQDASKMDSDDAASGSDSKKKKRYRPRDYTVNLDGHVTEGGVKPVRLKERKLTFDPMTGQIKPLTPKDPLQVEIPALTEQHRTETEKQEQKPNLQSPFEQTNWKELSRNEIIQSYLNRQSSLLSSSGVQTPGAHYFMSEYLKQEESTRKEARKTHVLAPNSKPTDLPGVTREVTSDDLNRICEHNWPGVNGCYDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD", "length": 693 }, "evidence": [ { "id": "A0A5G2QS76", "url": "https://omabrowser.org/oma/group/A0A5G2QS76/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LT16-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 26", "gene_name": "Med26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYILKRRKRPWRLSITQKAGTEISTRKDRPALPKRTKGMRSPKQIHPACPPAGPAAPPRFAQAMTAAPASPQQMRDRLLQAIDSQSNIRNMVAVLEVISSLERYPITKEALEETRLGKLINDVRKKTKNEELAKRAKRLLRSWQKLIEPVHQNEVALRALAGAAGSANGGAHNCRPELGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPHKVSKGSPDPLVPNASPLPTNGISGSPESLPSPLDGSGHLGPDGSRLELSENEKHSTKIPVNAVRPRPSSPGLGKPPVPCLQTKAAQLQPLDRADEPPGPPYPRGSPRCSISPRNSRHEGSFARHRSSYIPKGPVSSPSPRPQPLDTTQVPSPLPLAQPPTPPVRRLDLLPNAESPVHWPEQPEGHPRLTGPACRAGLSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIRPLTQKEPVRADSPVPTEQLPRTELEQQEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMAEYLKQEESSRQGARQPHVLLPLPTPTDLPGLTREVTQDDLDRIQAQQWPGVNGCEDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD", "length": 651 }, "evidence": [ { "id": "A0A5G2QS76", "url": "https://omabrowser.org/oma/group/A0A5G2QS76/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95402-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 26", "gene_name": "MED26", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAAPASPQQIRDRLLQAIDPQSNIRNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPAHQHEAALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGISGSPESFASSLDGSGHAGPEGSRLERDENDKHSGKIPVNAVRPHTSSPGLGKPPGPCLQPKASVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQQSLYAPKGSVPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLPSAESPVCWLEQPESHQRLAGPGCKAGLSPAEPLLSRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQQSRTELDKQEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRQGARQLHVLVPQSPPTDLPGLTREVTQDDLDRIQASQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD", "length": 600 }, "evidence": [ { "id": "A0A5G2QS76", "url": "https://omabrowser.org/oma/group/A0A5G2QS76/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TN02-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 26", "gene_name": "Med26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAAPASPQQMRDRLLQAIDSQSNIRNMVAVLEVISSLERYPITKEALEETRLGKLINDVRKKTKNEELAKRAKRLLRSWQKLIEPVHQNEVALRALAGAAGSANGGAHNCRPEMGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPHKVSKGSPDPLVPNASPLPTNGISGSPESLPSPLDGSGHLGPDGSRLEPSDNEKHSTKIPVNAVRPRPSSPGLGKPPVPCLQTKAAQLQQLDRADESPGPPYPRGSSRCSFSPRNSRHEGSFSRHRSSYIPKGQVSSPSPWPQPPDNTQVPSPLPLAQPPTPPVRRQELLPNAESPVHWPEQSEGHPRLTGPACRAGFSPDSSKADSDATSSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIRPLTQKEPVRADSPVPTEQLPRTELEQQEVKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMAEYLKQEESSRQGARQPHVLLPLPTPTDLPGLTREVTQDDLDRIQAQQWPGVNGCEDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD", "length": 588 }, "evidence": [ { "id": "A0A5G2QS76", "url": "https://omabrowser.org/oma/group/A0A5G2QS76/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS76", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS76", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS76", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS76", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS76", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS76", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS76", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QS76-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 572, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QS76-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QS76" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QS76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS76" }, { "id": "PS51319", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51319" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TFIIS N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 60, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QS96-1", "uniprot_ac": "A0A5G2QS96", "uniprot_id": "A0A5G2QS96_PIG", "mass": { "chemical_mass": 51628.0, "monoisotopic_mass": 51628.0 }, "refseq": {}, "gene_names": [ { "name": "CENPU", "type": "recommended", "evidence": [ { "id": "A0A5G2QS96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96" } ] } ], "protein_names": [ { "name": "Centromere protein U", "type": "recommended", "evidence": [ { "id": "A0A5G2QS96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96/entry#names_and_taxonomy" } ] }, { "name": "MLF1-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A5G2QS96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CENPU", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96", "locus": { "chromosome": "15", "start_pos": 45818951, "end_pos": 45851441, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015785", "url": "https://www.ensembl.org/id/ENSSSCG00000015785" } ] } } ], "crossref": [ { "id": "A0A5G2QS96", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QS96", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015785", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015785", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100515416", "url": "https://www.ncbi.nlm.nih.gov/gene/100515416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515416", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515416", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NTVGRTH", "url": "https://omabrowser.org/oma/group/NTVGRTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RSZ2", "url": "https://www.orthodb.org/?gene=F1RSZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32222", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32222", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32222:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32222:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-606279", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-606279", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68877", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QS96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS96-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSZ2", "url": "https://www.uniprot.org/uniprotkb/F1RSZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSZ2-1", "url": "https://www.uniprot.org/uniprotkb/F1RSZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQPGRVTRSGARYSENTVGRTQSMKDKPGRKHKPTDVFDFPDNSDISSISRLGENEKDEEPYETFAVRGHLGCFCLLTVTSNAALNMVCKYLFQSCFPIFWDMTRSGIAGSCDPPLHSTAIYADEEEFSRHVGPSLPSTPQGKEARSSSDTSEIEESENESVKISAKKPGRKLKPISDESESTEESDVRRKIKPAENISTQQHEAVAATASSELSEKPAESVPPKKTAPLNDESSVEKEILKTQRKEKMSHGKRKKSRNEAKDLDTSDCVPIWCLKEKKTSDIVDLDVVLSAFENIILEYKQKIDSRICKEAINKFHSNLKEQLIKMLKEVQMLQTLKRKKAKMISDIEKKRQRLIEVQDELLRLEPELQQLQIKYDELKERKSSLKNAAYFLSNLKQLHQDYSDIQEKEPNAKEMYDSSSLPALLFKARPLLGTENHLQNSNYQLEKLLDQK", "length": 454, "header": "tr|A0A5G2QS96-1|A0A5G2QS96_PIG Isoform 1 of Centromere protein U OS=Sus scrofa OX=9823 GN=CENPU PE=3 SV=1 CANONICAL=A0A5G2QS96-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QS96-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96/entry#A0A5G2QS96-1", "sequence": { "sequence": "MAQPGRVTRSGARYSENTVGRTQSMKDKPGRKHKPTDVFDFPDNSDISSISRLGENEKDEEPYETFAVRGHLGCFCLLTVTSNAALNMVCKYLFQSCFPIFWDMTRSGIAGSCDPPLHSTAIYADEEEFSRHVGPSLPSTPQGKEARSSSDTSEIEESENESVKISAKKPGRKLKPISDESESTEESDVRRKIKPAENISTQQHEAVAATASSELSEKPAESVPPKKTAPLNDESSVEKEILKTQRKEKMSHGKRKKSRNEAKDLDTSDCVPIWCLKEKKTSDIVDLDVVLSAFENIILEYKQKIDSRICKEAINKFHSNLKEQLIKMLKEVQMLQTLKRKKAKMISDIEKKRQRLIEVQDELLRLEPELQQLQIKYDELKERKSSLKNAAYFLSNLKQLHQDYSDIQEKEPNAKEMYDSSSLPALLFKARPLLGTENHLQNSNYQLEKLLDQK", "length": 454, "header": "tr|A0A5G2QS96-1|A0A5G2QS96_PIG Isoform 1 of Centromere protein U OS=Sus scrofa OX=9823 GN=CENPU PE=3 SV=1 CANONICAL=A0A5G2QS96-1" }, "locus": { "chromosome": "15", "start_pos": 45851117, "end_pos": 45819179, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076630.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076630.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066994.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066994.1" } ] } }, { "isoform_ac": "F1RSZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96/entry#F1RSZ2-1", "sequence": { "sequence": "MAQPGRVTRSGARYSENTVGRTQSMKDKPGRKHKPTDVFDFPDNSDISSISRLGENEKDEEPYETFDPPLHSTAIYADEEEFSRHVGPSLPSTPQGKEARSSSDTSEIEESENESVKISAKKPGRKLKPISDESESTEESDVRRKIKPAENISTQQHEAVAATASSELSEKPAESVPPKKTAPLNDESSVEKEILKTQRKEKMSHGKRKKSRNEAKDLDTSDCVPIWCLKEKKTSDIVDLDVVLSAFENIILEYKQKIDSRICKEAINKFHSNLKEQLIKMLKEVQMLQTLKRKKAKMISDIEKKRQRLIEVQDELLRLEPELQQLQIKYDELKERKSSLKNAAYFLSNLKQLHQDYSDIQEKEPNAKEMYDSSSLPALLFKARPLLGTENHLQNSNYQLEKLLDQK", "length": 407, "header": "tr|F1RSZ2-1|A0A5G2QS96_PIG Computationally mapped isoform of Centromere protein U OS=Sus scrofa OX=9823 GN=CENPU PE=3 SV=3 CANONICAL=A0A5G2QS96-1" }, "locus": { "chromosome": "15", "start_pos": 45851117, "end_pos": 45819179, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017188.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017188.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016727.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016727.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RSZ2", "url": "https://www.uniprot.org/uniprotkb/F1RSZ2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515416", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515416", "resource": "KEGG Pathway" }, { "id": "R-SSC-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-SSC-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-SSC-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-SSC-606279", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-606279", "resource": "Reactome", "description": "Deposition of new CENPA-containing nucleosomes at the centromere" }, { "id": "R-SSC-68877", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "resource": "Reactome", "description": "Mitotic Prometaphase" }, { "id": "R-SSC-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XZK8-1", "protein_name": "Centromere protein U", "gene_name": "CENPU", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSKKRTKRNRAGDEYKEHKGRSHPRRKFLPPEEPDVSRISKVAGVNQLEELCDSFDQPLHSTAVDACGEEHSENESSGYVPAPQRTNAERSEKMLLETPEGDVHEFSQSGSAREPLMENLNAPNTTRPEVKKKRPSKKSSSDSSVNSPSSVQLWCPNKLKRSSRDITELDVVLAEFEKIAANYRQSIESKACRKAVSAFCSAFEDQVTDLITEVQELKNTKKKNAKVVADIKKKRQRLMQVREKLSRTEPQLIKLQKEYAEVEERRSSLRQVVQFLTDLKELQQDYLDYREENPRKKVVYGASSLPALLVESRRILQAERHFQNINRKLEYALEVQRGKLAKEH", "length": 345 }, "evidence": [ { "id": "A0A5G2QS96", "url": "https://omabrowser.org/oma/group/A0A5G2QS96/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q4V8G7-1", "protein_name": "Centromere protein U", "gene_name": "Cenpu", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAARRSLRYSGDPGAKRSRNTLGSTNSRKQKAGQKPKRKDVFDFPNTSDVSSMLRELEEEEPYETFDPPLHSTAIYTDDELYKHCVSSTSPATHRGKESRNLNPSENEASGNDSIKLSAKKPRRKLEPISDESDSSEDNVRRSVSIERPRARKPPAAPAAASSSSSPSERPAEQVTPRKTSFPQPSAVEETPAAQSQLKTQKKVRPSPGRRKRPRRGSTHSDASESMHILCLEGKRQSDVMELDVVLSAFERTFLDYKQRVESESCNQAISKFYFKIKGELIRMLKEVQMLKALKRKNTKIISNMEKKRQRLIDVQDELIRLEPQLKQLQTKYDDLKKRKSALKNSKHFLSNLKQLYQDYSNVREEEPKEKEKYDSSSLPALLFKARSILGAEKHLKTINYHLGKLLKQD", "length": 410 }, "evidence": [ { "id": "A0A5G2QS96", "url": "https://omabrowser.org/oma/group/A0A5G2QS96/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q71F23-1", "protein_name": "Centromere protein U", "gene_name": "CENPU", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPRGRRRPRPHRSEGARRSKNTLERTHSMKDKAGQKCKPIDVFDFPDNSDVSSIGRLGENEKDEETYETFDPPLHSTAIYADEEEFSKHCGLSLSSTPPGKEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLTNLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLPALLFKARTLLGAESHLRNINHQLEKLLDQG", "length": 418 }, "evidence": [ { "id": "A0A5G2QS96", "url": "https://omabrowser.org/oma/group/A0A5G2QS96/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C4M7-1", "protein_name": "Centromere protein U", "gene_name": "Cenpu", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAARRSLRYSGNPGAKHSKNTLRSTYSRKQKAGPKPRPKDVFDFSNNSDASSIPGALEEEEETYETFDPPLHSTAIYAEDELSKHCVSSSSLATHRGKASRNLDPSEDEASGNESIKVSTKKPRRKLEPISGESDSSADDVRRRVASAEGPRSQQRQAAPAAPSPPERPAEPVTPRRTRLHSAQLSPVDETPATQSQLKTQKKVRPSPGRRKRPRRGHTDTDGSESMHIWCLEGKRQSDITELDVILSVFEKTFLEYKQRVESESCNQAINKFYFKMKGELIRMLKEAQMLKALKMKNTKIIANMEKKRQRLIEVQDELIRLEPQLKQLQTKYDDLKERKSSLKKSKHFLSNLKQLCQDYSNVQEKGPKGTGKYDSSSLPALLFKARSILGAENHLRTINYQLGKLLELD", "length": 410 }, "evidence": [ { "id": "A0A5G2QS96", "url": "https://omabrowser.org/oma/group/A0A5G2QS96/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QS96-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 454, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QS96-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QS96" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 198, "end_pos": 200 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSA7-1", "uniprot_ac": "A0A5G2QSA7", "uniprot_id": "A0A5G2QSA7_PIG", "mass": { "chemical_mass": 21831.0, "monoisotopic_mass": 21831.0 }, "refseq": {}, "gene_names": [ { "name": "NDUFB9", "type": "recommended", "evidence": [ { "id": "A0A5G2QSA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "type": "recommended", "evidence": [ { "id": "A0A5G2QSA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7/entry#names_and_taxonomy" } ] }, { "name": "Complex I-B22", "type": "synonym", "evidence": [ { "id": "A0A5G2QSA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7/entry#names_and_taxonomy" } ] }, { "name": "NADH-ubiquinone oxidoreductase B22 subunit", "type": "synonym", "evidence": [ { "id": "A0A5G2QSA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.", "evidence": [ { "database": "UniProtKB", "id": "K7GSE5", "url": "https://www.uniprot.org/uniprotkb/K7GSE5#function" }, { "database": "UniProtKB", "id": "ARBA00002920", "url": "https://www.uniprot.org/uniprotkb/ARBA00002920#function" }, { "database": "UniProtKB", "id": "A0A5G2QSA7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7#function" }, { "database": "UniProtKB", "id": "A0A5G2R954", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R954#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSA7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NDUFB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7", "locus": { "chromosome": "4", "start_pos": 15105305, "end_pos": 15113550, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005976", "url": "https://www.ensembl.org/id/ENSSSCG00000005976" } ] } } ], "crossref": [ { "id": "A0A5G2QSA7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSA7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005976", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005976", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "5GPN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5GPN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "5GUP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5GUP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2C", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2C&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2D&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2E", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2E&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2F", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2F&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2H", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2H&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2K", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2K&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V30", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V30&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V31", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V31&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V32", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V32&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V33", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V33&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V3M", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V3M&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VBL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VBL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VBP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VBP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VC0", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VC0&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VWL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VWL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VXS", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VXS&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VY1", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VY1&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VY9", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VY9&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYE", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYE&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYG", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYG&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYI", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYI&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYS", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYS&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZ8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZ8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZV", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZV&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W00", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W00&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W0H", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W0H&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W0R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W0R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1O", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1O&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1P", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1P&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1T", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1T&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1U", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1U&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1V", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1V&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W20", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W20&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2K", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2K&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2L", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2L&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2U", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2U&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2Y", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2Y&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W31", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W31&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W32", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W32&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W35", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W35&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4C", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4C&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4D&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4E", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4E&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4F", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4F&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4G", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4G&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4J", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4J&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4K", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4K&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4L", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4L&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4M", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4M&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4N", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4N&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4Q", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4Q&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UD1", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UD1&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEO", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEO&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UER", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UER&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UES", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UES&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UET", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UET&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEU", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEU&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEV", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEV&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEX", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEX&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEY", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEY&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGI", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGI&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGJ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGJ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZO8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZO8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZOU", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZOU&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZP8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZP8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSK", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSK&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSM", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSM&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSO", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSO&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZXZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZXZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9BUH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9BUH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9BWD", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9BWD&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9BXV", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9BXV&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CD6", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CD6&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CDN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CDN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CE2", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CE2&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9J6H", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9J6H&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9J6W", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9J6W&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR008011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12868", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12868", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12868:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12868:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00005gpn", "url": "https://www.rcsb.org/structure/pdb_00005gpn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00005gup", "url": "https://www.rcsb.org/structure/pdb_00005gup", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2c", "url": "https://www.rcsb.org/structure/pdb_00007v2c", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2d", "url": "https://www.rcsb.org/structure/pdb_00007v2d", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2e", "url": "https://www.rcsb.org/structure/pdb_00007v2e", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2f", "url": "https://www.rcsb.org/structure/pdb_00007v2f", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2h", "url": "https://www.rcsb.org/structure/pdb_00007v2h", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2k", "url": "https://www.rcsb.org/structure/pdb_00007v2k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2r", "url": "https://www.rcsb.org/structure/pdb_00007v2r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v30", "url": "https://www.rcsb.org/structure/pdb_00007v30", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v31", "url": "https://www.rcsb.org/structure/pdb_00007v31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v32", "url": "https://www.rcsb.org/structure/pdb_00007v32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v33", "url": "https://www.rcsb.org/structure/pdb_00007v33", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v3m", "url": "https://www.rcsb.org/structure/pdb_00007v3m", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vbl", "url": "https://www.rcsb.org/structure/pdb_00007vbl", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vbp", "url": "https://www.rcsb.org/structure/pdb_00007vbp", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vc0", "url": "https://www.rcsb.org/structure/pdb_00007vc0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vwl", "url": "https://www.rcsb.org/structure/pdb_00007vwl", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vxs", "url": "https://www.rcsb.org/structure/pdb_00007vxs", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vy1", "url": "https://www.rcsb.org/structure/pdb_00007vy1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vy9", "url": "https://www.rcsb.org/structure/pdb_00007vy9", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vye", "url": "https://www.rcsb.org/structure/pdb_00007vye", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vyg", "url": "https://www.rcsb.org/structure/pdb_00007vyg", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vyi", "url": "https://www.rcsb.org/structure/pdb_00007vyi", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vys", "url": "https://www.rcsb.org/structure/pdb_00007vys", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vz8", "url": "https://www.rcsb.org/structure/pdb_00007vz8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vzv", "url": "https://www.rcsb.org/structure/pdb_00007vzv", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vzw", "url": "https://www.rcsb.org/structure/pdb_00007vzw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w00", "url": "https://www.rcsb.org/structure/pdb_00007w00", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w0h", "url": "https://www.rcsb.org/structure/pdb_00007w0h", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w0r", "url": "https://www.rcsb.org/structure/pdb_00007w0r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1o", "url": "https://www.rcsb.org/structure/pdb_00007w1o", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1p", "url": "https://www.rcsb.org/structure/pdb_00007w1p", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1t", "url": "https://www.rcsb.org/structure/pdb_00007w1t", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1u", "url": "https://www.rcsb.org/structure/pdb_00007w1u", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1v", "url": "https://www.rcsb.org/structure/pdb_00007w1v", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1z", "url": "https://www.rcsb.org/structure/pdb_00007w1z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w20", "url": "https://www.rcsb.org/structure/pdb_00007w20", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2k", "url": "https://www.rcsb.org/structure/pdb_00007w2k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2l", "url": "https://www.rcsb.org/structure/pdb_00007w2l", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2r", "url": "https://www.rcsb.org/structure/pdb_00007w2r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2u", "url": "https://www.rcsb.org/structure/pdb_00007w2u", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2y", "url": "https://www.rcsb.org/structure/pdb_00007w2y", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w31", "url": "https://www.rcsb.org/structure/pdb_00007w31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w32", "url": "https://www.rcsb.org/structure/pdb_00007w32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w35", "url": "https://www.rcsb.org/structure/pdb_00007w35", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4c", "url": "https://www.rcsb.org/structure/pdb_00007w4c", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4d", "url": "https://www.rcsb.org/structure/pdb_00007w4d", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4e", "url": "https://www.rcsb.org/structure/pdb_00007w4e", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4f", "url": "https://www.rcsb.org/structure/pdb_00007w4f", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4g", "url": "https://www.rcsb.org/structure/pdb_00007w4g", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4j", "url": "https://www.rcsb.org/structure/pdb_00007w4j", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4k", "url": "https://www.rcsb.org/structure/pdb_00007w4k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4l", "url": "https://www.rcsb.org/structure/pdb_00007w4l", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4m", "url": "https://www.rcsb.org/structure/pdb_00007w4m", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4n", "url": "https://www.rcsb.org/structure/pdb_00007w4n", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4q", "url": "https://www.rcsb.org/structure/pdb_00007w4q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ud1", "url": "https://www.rcsb.org/structure/pdb_00008ud1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ueo", "url": "https://www.rcsb.org/structure/pdb_00008ueo", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uep", "url": "https://www.rcsb.org/structure/pdb_00008uep", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ueq", "url": "https://www.rcsb.org/structure/pdb_00008ueq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uer", "url": "https://www.rcsb.org/structure/pdb_00008uer", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ues", "url": "https://www.rcsb.org/structure/pdb_00008ues", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uet", "url": "https://www.rcsb.org/structure/pdb_00008uet", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ueu", "url": "https://www.rcsb.org/structure/pdb_00008ueu", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uev", "url": "https://www.rcsb.org/structure/pdb_00008uev", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uew", "url": "https://www.rcsb.org/structure/pdb_00008uew", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uex", "url": "https://www.rcsb.org/structure/pdb_00008uex", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uey", "url": "https://www.rcsb.org/structure/pdb_00008uey", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uez", "url": "https://www.rcsb.org/structure/pdb_00008uez", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugh", "url": "https://www.rcsb.org/structure/pdb_00008ugh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugi", "url": "https://www.rcsb.org/structure/pdb_00008ugi", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugj", "url": "https://www.rcsb.org/structure/pdb_00008ugj", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugn", "url": "https://www.rcsb.org/structure/pdb_00008ugn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugr", "url": "https://www.rcsb.org/structure/pdb_00008ugr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zo8", "url": "https://www.rcsb.org/structure/pdb_00008zo8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zou", "url": "https://www.rcsb.org/structure/pdb_00008zou", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zp8", "url": "https://www.rcsb.org/structure/pdb_00008zp8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsk", "url": "https://www.rcsb.org/structure/pdb_00008zsk", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsl", "url": "https://www.rcsb.org/structure/pdb_00008zsl", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsm", "url": "https://www.rcsb.org/structure/pdb_00008zsm", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsn", "url": "https://www.rcsb.org/structure/pdb_00008zsn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zso", "url": "https://www.rcsb.org/structure/pdb_00008zso", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsq", "url": "https://www.rcsb.org/structure/pdb_00008zsq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsr", "url": "https://www.rcsb.org/structure/pdb_00008zsr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zxz", "url": "https://www.rcsb.org/structure/pdb_00008zxz", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009buh", "url": "https://www.rcsb.org/structure/pdb_00009buh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009bwd", "url": "https://www.rcsb.org/structure/pdb_00009bwd", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009bxv", "url": "https://www.rcsb.org/structure/pdb_00009bxv", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009cd6", "url": "https://www.rcsb.org/structure/pdb_00009cd6", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009cdn", "url": "https://www.rcsb.org/structure/pdb_00009cdn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009ce2", "url": "https://www.rcsb.org/structure/pdb_00009ce2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009j6h", "url": "https://www.rcsb.org/structure/pdb_00009j6h", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009j6w", "url": "https://www.rcsb.org/structure/pdb_00009j6w", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5GPN", "url": "https://www.rcsb.org/structure/5GPN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5GUP", "url": "https://www.rcsb.org/structure/5GUP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2C", "url": "https://www.rcsb.org/structure/7V2C", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2D", "url": "https://www.rcsb.org/structure/7V2D", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2E", "url": "https://www.rcsb.org/structure/7V2E", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2F", "url": "https://www.rcsb.org/structure/7V2F", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2H", "url": "https://www.rcsb.org/structure/7V2H", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2K", "url": "https://www.rcsb.org/structure/7V2K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2R", "url": "https://www.rcsb.org/structure/7V2R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V30", "url": "https://www.rcsb.org/structure/7V30", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V31", "url": "https://www.rcsb.org/structure/7V31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V32", "url": "https://www.rcsb.org/structure/7V32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V33", "url": "https://www.rcsb.org/structure/7V33", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V3M", "url": "https://www.rcsb.org/structure/7V3M", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VBL", "url": "https://www.rcsb.org/structure/7VBL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VBP", "url": "https://www.rcsb.org/structure/7VBP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VC0", "url": "https://www.rcsb.org/structure/7VC0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VWL", "url": "https://www.rcsb.org/structure/7VWL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VXS", "url": "https://www.rcsb.org/structure/7VXS", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VY1", "url": "https://www.rcsb.org/structure/7VY1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VY9", "url": "https://www.rcsb.org/structure/7VY9", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYE", "url": "https://www.rcsb.org/structure/7VYE", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYG", "url": "https://www.rcsb.org/structure/7VYG", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYI", "url": "https://www.rcsb.org/structure/7VYI", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYS", "url": "https://www.rcsb.org/structure/7VYS", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZ8", "url": "https://www.rcsb.org/structure/7VZ8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZV", "url": "https://www.rcsb.org/structure/7VZV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZW", "url": "https://www.rcsb.org/structure/7VZW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W00", "url": "https://www.rcsb.org/structure/7W00", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W0H", "url": "https://www.rcsb.org/structure/7W0H", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W0R", "url": "https://www.rcsb.org/structure/7W0R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1O", "url": "https://www.rcsb.org/structure/7W1O", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1P", "url": "https://www.rcsb.org/structure/7W1P", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1T", "url": "https://www.rcsb.org/structure/7W1T", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1U", "url": "https://www.rcsb.org/structure/7W1U", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1V", "url": "https://www.rcsb.org/structure/7W1V", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1Z", "url": "https://www.rcsb.org/structure/7W1Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W20", "url": "https://www.rcsb.org/structure/7W20", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2K", "url": "https://www.rcsb.org/structure/7W2K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2L", "url": "https://www.rcsb.org/structure/7W2L", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2R", "url": "https://www.rcsb.org/structure/7W2R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2U", "url": "https://www.rcsb.org/structure/7W2U", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2Y", "url": "https://www.rcsb.org/structure/7W2Y", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W31", "url": "https://www.rcsb.org/structure/7W31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W32", "url": "https://www.rcsb.org/structure/7W32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W35", "url": "https://www.rcsb.org/structure/7W35", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4C", "url": "https://www.rcsb.org/structure/7W4C", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4D", "url": "https://www.rcsb.org/structure/7W4D", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4E", "url": "https://www.rcsb.org/structure/7W4E", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4F", "url": "https://www.rcsb.org/structure/7W4F", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4G", "url": "https://www.rcsb.org/structure/7W4G", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4J", "url": "https://www.rcsb.org/structure/7W4J", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4K", "url": "https://www.rcsb.org/structure/7W4K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4L", "url": "https://www.rcsb.org/structure/7W4L", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4M", "url": "https://www.rcsb.org/structure/7W4M", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4N", "url": "https://www.rcsb.org/structure/7W4N", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4Q", "url": "https://www.rcsb.org/structure/7W4Q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UD1", "url": "https://www.rcsb.org/structure/8UD1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEO", "url": "https://www.rcsb.org/structure/8UEO", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEP", "url": "https://www.rcsb.org/structure/8UEP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEQ", "url": "https://www.rcsb.org/structure/8UEQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UER", "url": "https://www.rcsb.org/structure/8UER", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UES", "url": "https://www.rcsb.org/structure/8UES", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UET", "url": "https://www.rcsb.org/structure/8UET", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEU", "url": "https://www.rcsb.org/structure/8UEU", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEV", "url": "https://www.rcsb.org/structure/8UEV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEW", "url": "https://www.rcsb.org/structure/8UEW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEX", "url": "https://www.rcsb.org/structure/8UEX", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEY", "url": "https://www.rcsb.org/structure/8UEY", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEZ", "url": "https://www.rcsb.org/structure/8UEZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGH", "url": "https://www.rcsb.org/structure/8UGH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGI", "url": "https://www.rcsb.org/structure/8UGI", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGJ", "url": "https://www.rcsb.org/structure/8UGJ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGN", "url": "https://www.rcsb.org/structure/8UGN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGR", "url": "https://www.rcsb.org/structure/8UGR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZO8", "url": "https://www.rcsb.org/structure/8ZO8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZOU", "url": "https://www.rcsb.org/structure/8ZOU", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZP8", "url": "https://www.rcsb.org/structure/8ZP8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSK", "url": "https://www.rcsb.org/structure/8ZSK", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSL", "url": "https://www.rcsb.org/structure/8ZSL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSM", "url": "https://www.rcsb.org/structure/8ZSM", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSN", "url": "https://www.rcsb.org/structure/8ZSN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSO", "url": "https://www.rcsb.org/structure/8ZSO", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSQ", "url": "https://www.rcsb.org/structure/8ZSQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSR", "url": "https://www.rcsb.org/structure/8ZSR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZXZ", "url": "https://www.rcsb.org/structure/8ZXZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9BUH", "url": "https://www.rcsb.org/structure/9BUH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9BWD", "url": "https://www.rcsb.org/structure/9BWD", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9BXV", "url": "https://www.rcsb.org/structure/9BXV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CD6", "url": "https://www.rcsb.org/structure/9CD6", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CDN", "url": "https://www.rcsb.org/structure/9CDN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CE2", "url": "https://www.rcsb.org/structure/9CE2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9J6H", "url": "https://www.rcsb.org/structure/9J6H", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9J6W", "url": "https://www.rcsb.org/structure/9J6W", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF05347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QSA7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R954", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R954", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R954-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R954-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GSE5", "url": "https://www.uniprot.org/uniprotkb/K7GSE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GSE5-1", "url": "https://www.uniprot.org/uniprotkb/K7GSE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFSAPAAYLTHQQKVLRLYKRALRHLESWCVHRDKYRYFACLMRARFDEHKNEKDMVKATQLLRQAEEEFWYGQHPQPYIFPESPGGTSYERYECYKVPEWCLDDWHPSEKAMYPDYFAKREQWKRLRRESWEREVSLELRFCSPCAEVQVPALTVTLAPCLSDILSLSSVLNGTSAPVLKID", "length": 184, "header": "tr|A0A5G2QSA7-1|A0A5G2QSA7_PIG Isoform 1 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Sus scrofa OX=9823 GN=NDUFB9 PE=1 SV=2 CANONICAL=A0A5G2QSA7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7/entry#A0A5G2QSA7-1", "sequence": { "sequence": "MAFSAPAAYLTHQQKVLRLYKRALRHLESWCVHRDKYRYFACLMRARFDEHKNEKDMVKATQLLRQAEEEFWYGQHPQPYIFPESPGGTSYERYECYKVPEWCLDDWHPSEKAMYPDYFAKREQWKRLRRESWEREVSLELRFCSPCAEVQVPALTVTLAPCLSDILSLSSVLNGTSAPVLKID", "length": 184, "header": "tr|A0A5G2QSA7-1|A0A5G2QSA7_PIG Isoform 1 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Sus scrofa OX=9823 GN=NDUFB9 PE=1 SV=2 CANONICAL=A0A5G2QSA7-1" }, "locus": { "chromosome": "4", "start_pos": 15113225, "end_pos": 15108699, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079935.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079935.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067692.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067692.2" } ] } }, { "isoform_ac": "A0A5G2R954-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7/entry#A0A5G2R954-1", "sequence": { "sequence": "MAFSAPAAYLTHQQKVLRLYKRALRHLESWCVHRDKYRYFACLMRARFDEHKNEKDMVKATQLLRQAEEEFWYGQHPQPYIFPESPGGTSYERYECYKVPEWCLDDWHPSEKAMYPDYFAKREQWKRLRRESWEREVSLAYFFFGQHPEGVRFCSPCAEVQVPALTVTLAPCLSDILS", "length": 178, "header": "tr|A0A5G2R954-1|A0A5G2R954_PIG Computationally mapped isoform of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Sus scrofa OX=9823 GN=NDUFB9 PE=1 SV=1 CANONICAL=A0A5G2QSA7-1" }, "locus": { "chromosome": "4", "start_pos": 15113225, "end_pos": 15108747, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083219.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083219.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073813.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073813.1" } ] } }, { "isoform_ac": "K7GSE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7/entry#K7GSE5-1", "sequence": { "sequence": "MTAALAPPRRKRKWPPLAPPFRGSPTPRFPAAPAAAEGERAVMAFSAPAAYLTHQQKVLRLYKRALRHLESWCVHRDKYRYFACLMRARFDEHKNEKDMVKATQLLRQAEEEFWYGQHPQPYIFPESPGGTSYERYECYKVPEWCLDDWHPSEKAMYPDYFAKREQWKRLRRESWEREVKQLQEETPPGGPRTEALPPARKEGDLPPLWWHIVTRPRERPM", "length": 221, "header": "tr|K7GSE5-1|A0A5G2QSA7_PIG Computationally mapped isoform of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Sus scrofa OX=9823 GN=NDUFB9 PE=1 SV=2 CANONICAL=A0A5G2QSA7-1" }, "locus": { "chromosome": "4", "start_pos": 15113351, "end_pos": 15105392, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035108.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035108.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030827.2", "url": "https://www.ensembl.org/id/ENSSSCP00000030827.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The architecture of the mammalian respirasome.", "journal": "Nature", "date": "2016", "authors": "Gu Jinke, Wu Meng, Guo Runyu, Yan Kaige, Lei Jianlin, Gao Ning, Yang Maojun", "evidence": [ { "database": "UniProtKB", "id": "K7GSE5", "url": "https://www.uniprot.org/uniprotkb/K7GSE5" } ], "reference": [ { "type": "PubMed", "id": "27654917", "url": "https://glygen.org/publication/PubMed/27654917" } ] }, { "title": "Structure of Mammalian Respiratory Supercomplex I1III2IV1.", "journal": "Cell", "date": "2016", "authors": "Wu Meng, Gu Jinke, Guo Runyu, Huang Yushen, Yang Maojun", "evidence": [ { "database": "UniProtKB", "id": "K7GSE5", "url": "https://www.uniprot.org/uniprotkb/K7GSE5" } ], "reference": [ { "type": "PubMed", "id": "27912063", "url": "https://glygen.org/publication/PubMed/27912063" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "K7GSE5", "url": "https://www.uniprot.org/uniprotkb/K7GSE5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "The coupling mechanism of mammalian mitochondrial complex I.", "journal": "Nat. Struct. Mol. Biol.", "date": "2022", "authors": "Gu Jinke, Liu Tianya, Guo Runyu, Zhang Laixing, Yang Maojun", "evidence": [ { "database": "UniProtKB", "id": "K7GSE5", "url": "https://www.uniprot.org/uniprotkb/K7GSE5" } ], "reference": [ { "type": "PubMed", "id": "35145322", "url": "https://glygen.org/publication/PubMed/35145322" } ] }, { "title": "High-resolution in situ structures of mammalian respiratory supercomplexes.", "journal": "Nature", "date": "2024", "authors": "Zheng Wan, Chai Pengxin, Zhu Jiapeng, Zhang Kai", "evidence": [ { "database": "UniProtKB", "id": "K7GSE5", "url": "https://www.uniprot.org/uniprotkb/K7GSE5" } ], "reference": [ { "type": "PubMed", "id": "38811722", "url": "https://glygen.org/publication/PubMed/38811722" } ] } ], "pathway": [ { "id": "R-SSC-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-SSC-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSA7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSA7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial electron transport, NADH to ubiquinone", "id": "GO:0006120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006120", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSA7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSA7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 184, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSA7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSA7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSA7" }, { "id": "PF05347", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05347" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Complex 1 LYR protein", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 72, "start_aa": "Gln", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSB9-1", "uniprot_ac": "A0A5G2QSB9", "uniprot_id": "A0A5G2QSB9_PIG", "mass": { "chemical_mass": 64242.0, "monoisotopic_mass": 64242.0 }, "refseq": {}, "gene_names": [ { "name": "BRAP", "type": "recommended", "evidence": [ { "id": "A0A5G2QSB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ] } ], "protein_names": [ { "name": "BRCA1-associated protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QSB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A5G2QSB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9/entry#names_and_taxonomy" } ] }, { "name": "BRAP2", "type": "synonym", "evidence": [ { "id": "A0A5G2QSB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9/entry#names_and_taxonomy" } ] }, { "name": "Impedes mitogenic signal propagation", "type": "synonym", "evidence": [ { "id": "A0A5G2QSB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase BRAP2", "type": "synonym", "evidence": [ { "id": "A0A5G2QSB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9#function" }, { "database": "UniProtKB", "id": "ARBA00053069", "url": "https://www.uniprot.org/uniprotkb/ARBA00053069#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BRAP", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9", "locus": { "chromosome": "14", "start_pos": 32800749, "end_pos": 32841743, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040595", "url": "https://www.ensembl.org/id/ENSSSCG00000040595" } ] } } ], "crossref": [ { "id": "A0A5G2QSB9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSB9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000040595", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000040595", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12718", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12718", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16457", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16457", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24007", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24007", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24007:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24007:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02148", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02148", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5673000", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5673000", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5675221", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5675221", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDEEIKKKTLASAVACLEGKSPGEKAALIHQHLGRREMTDMIIETMKSNPDELEATEEERKSSEASPTAQRSKDQSKECVNGAPDSPSKQLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPATMTSHDLMKFVAPFNEVIEQMKIIRDSTPNQYMVLIKFSAQADADSFYMACNGRQFNSIEDDVCQLVYVERAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHRLNDLLKEKQSVERKCTQLNTKVAKLTTELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDMQITEIREQLRDVMFYLETQQKISHLPAEARQEIQEGQINIPMASASSPSSSGGSGKLSSRKGRSKRGK", "length": 562, "header": "tr|A0A5G2QSB9-1|A0A5G2QSB9_PIG Isoform 1 of BRCA1-associated protein OS=Sus scrofa OX=9823 GN=BRAP PE=4 SV=1 CANONICAL=A0A5G2QSB9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9/entry#A0A5G2QSB9-1", "sequence": { "sequence": "MSDEEIKKKTLASAVACLEGKSPGEKAALIHQHLGRREMTDMIIETMKSNPDELEATEEERKSSEASPTAQRSKDQSKECVNGAPDSPSKQLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPATMTSHDLMKFVAPFNEVIEQMKIIRDSTPNQYMVLIKFSAQADADSFYMACNGRQFNSIEDDVCQLVYVERAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHRLNDLLKEKQSVERKCTQLNTKVAKLTTELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDMQITEIREQLRDVMFYLETQQKISHLPAEARQEIQEGQINIPMASASSPSSSGGSGKLSSRKGRSKRGK", "length": 562, "header": "tr|A0A5G2QSB9-1|A0A5G2QSB9_PIG Isoform 1 of BRCA1-associated protein OS=Sus scrofa OX=9823 GN=BRAP PE=4 SV=1 CANONICAL=A0A5G2QSB9-1" }, "locus": { "chromosome": "14", "start_pos": 32839402, "end_pos": 32802813, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091016.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091016.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064902.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064902.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5673000", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5673000", "resource": "Reactome", "description": "RAF activation" }, { "id": "R-SSC-5675221", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5675221", "resource": "Reactome", "description": "Negative regulation of MAPK pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSB9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-5672966", "name": "RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5672966", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5672966" } ] }, { "id": "R-SSC-5674018", "name": "BRAP binds RAS:GTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5674018", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5674018" } ] }, { "id": "R-SSC-5674019", "name": "BRAP binds KSR1:MARK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5674019", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5674019" } ] }, { "id": "R-SSC-5674022", "name": "BRAP autoubiquitinates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5674022", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5674022" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSB9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 562, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSB9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSB9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 274, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QSB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSB9" }, { "id": "PS50271", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50271" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBP-type", "eco_id": "ECO_0000259", "start_pos": 271, "end_pos": 363, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 254, "end_pos": 256 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSC5-1", "uniprot_ac": "A0A5G2QSC5", "uniprot_id": "A0A5G2QSC5_PIG", "mass": { "chemical_mass": 193356.0, "monoisotopic_mass": 193356.0 }, "refseq": {}, "gene_names": [ { "name": "XRN1", "type": "recommended", "evidence": [ { "id": "A0A5G2QSC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ] } ], "protein_names": [ { "name": "5'-3' exoribonuclease 1", "type": "recommended", "evidence": [ { "id": "A0A5G2QSC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5/entry#names_and_taxonomy" } ] }, { "name": "3.1.13.-", "type": "synonym", "evidence": [ { "id": "A0A5G2QSC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "XRN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5", "locus": { "chromosome": "13", "start_pos": 83065957, "end_pos": 83174477, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011678", "url": "https://www.ensembl.org/id/ENSSSCG00000011678" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011678", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011678", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18673", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18673", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12341", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12341", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12341:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12341:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17846", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17846", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18332", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18332", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-450385", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450385", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-450513", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450513", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKDKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYITILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEAKNYKEKKKTKGQENSVCWAALDKNGEEVVTSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWFYPYHYAPFLSDIRNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPTCYQHLMTSEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDGDTEFTYPSPWPEKFPAIERCHTRYRIISLDAWRVDISKNKITRVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENMMLEILVNAESDELSVENIASSVLGKSVFVNWPHLEEARVVGISDGETKFYLEEPPGTQKLYLGRTVPPSKVVHLDKEQSNWTKEVQGISEYYLRRKGIIINETSAVVYGQLLTGRKYQINQNGEVRLEKQWSKQVLPFVYQTIVKDVRAFDSRFSSIKTLDDLFPPRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFRLFDRVVNVRENFSVPIGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGSQKLTAIVKPQPAVNHYSSNSSVSSGHLGGLNHSPQSLFVPTQVPAKDDDEFCNIWQSLQESGKVQHFQPALQEKGAVLPQEISQVTQHNKSGFNDNSVKQRKHEPHKKFKEECKSPKTESRSQKMSNRQPNPGIENFLASLNIAKENEVQLSHHEEPPNEEHLSPQSFAMGTRMLKEILKIDGSGTLDHKSEMKQFGNEVTVSSNRRDEYGSSSQPKQNKKLTSYTNKPHSASEYHNVQSLDSMCWPALSQIPPVSTPVTELSRICSLVGMPQPDFSFLRTPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGVNFPLPPPIFPSYPPAVPPGTIPPVFPQPTGWDHYGSNLALGAANIMPSSTHLFGSMPWGPPVPVPGKPFHHTSYAGTMPMAGGMPAGVHNQFIPLQVTKKRVANKKNFENKETQSSHATPLQTSQSASSDVTKAVPQESSSASLKSSQNIQPASSLQAEAASPGHSMSHHKSTPSSSSRRKSRKLAVNFGISKPSE", "length": 1703, "header": "tr|A0A5G2QSC5-1|A0A5G2QSC5_PIG Isoform 1 of 5'-3' exoribonuclease 1 OS=Sus scrofa OX=9823 GN=XRN1 PE=3 SV=1 CANONICAL=A0A5G2QSC5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5/entry#A0A5G2QSC5-1", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKDKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYITILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEAKNYKEKKKTKGQENSVCWAALDKNGEEVVTSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWFYPYHYAPFLSDIRNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPTCYQHLMTSEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDGDTEFTYPSPWPEKFPAIERCHTRYRIISLDAWRVDISKNKITRVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENMMLEILVNAESDELSVENIASSVLGKSVFVNWPHLEEARVVGISDGETKFYLEEPPGTQKLYLGRTVPPSKVVHLDKEQSNWTKEVQGISEYYLRRKGIIINETSAVVYGQLLTGRKYQINQNGEVRLEKQWSKQVLPFVYQTIVKDVRAFDSRFSSIKTLDDLFPPRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFRLFDRVVNVRENFSVPIGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGSQKLTAIVKPQPAVNHYSSNSSVSSGHLGGLNHSPQSLFVPTQVPAKDDDEFCNIWQSLQESGKVQHFQPALQEKGAVLPQEISQVTQHNKSGFNDNSVKQRKHEPHKKFKEECKSPKTESRSQKMSNRQPNPGIENFLASLNIAKENEVQLSHHEEPPNEEHLSPQSFAMGTRMLKEILKIDGSGTLDHKSEMKQFGNEVTVSSNRRDEYGSSSQPKQNKKLTSYTNKPHSASEYHNVQSLDSMCWPALSQIPPVSTPVTELSRICSLVGMPQPDFSFLRTPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGVNFPLPPPIFPSYPPAVPPGTIPPVFPQPTGWDHYGSNLALGAANIMPSSTHLFGSMPWGPPVPVPGKPFHHTSYAGTMPMAGGMPAGVHNQFIPLQVTKKRVANKKNFENKETQSSHATPLQTSQSASSDVTKAVPQESSSASLKSSQNIQPASSLQAEAASPGHSMSHHKSTPSSSSRRKSRKLAVNFGISKPSE", "length": 1703, "header": "tr|A0A5G2QSC5-1|A0A5G2QSC5_PIG Isoform 1 of 5'-3' exoribonuclease 1 OS=Sus scrofa OX=9823 GN=XRN1 PE=3 SV=1 CANONICAL=A0A5G2QSC5-1" }, "locus": { "chromosome": "13", "start_pos": 83174402, "end_pos": 83068937, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069947.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069947.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067024.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067024.1" } ] } }, { "isoform_ac": "A0A5G2RBD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5/entry#A0A5G2RBD4-1", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKDKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYITILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEAKNYKEKKKTKGQENSVCWAALDKNGEEVVTSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWFYPYHYAPFLSDIRNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPTCYQHLMTSEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDGDTEFTYPSPWPEKFPAIERCHTRYRIISLDAWRVDISKNKITRVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENMMLEILVNAESDELSVENIASSVLGKSVFVNWPHLEEARVVGISDGETKFYLEEPPGTQKLYLGRTVPPSKVVHLDKEQSNWTKEVQGISEYYLRRKGIIINETSAVVYGQLLTGRKYQINQNGEVRLEKQWSKQVLPFVYQTIVKDVRAFDSRFSSIKTLDDLFPPRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFRLFDRVVNVRENFSVPIGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGSQKLTAIVKPQPAVNHYSSNSSVSSGHLGGLNHSPQSLFVPTQVPAKDDDEFCNIWQSLQESGKVQHFQPALQEKGAVLPQEISQVTQHNKSGFNDNSVKQRKHEPHKKFKEECKSPKTESRSQKMSNRQPNPGIENFLASLNIAKENEVQLSHHEEPPNEEHLSPQSFAMKGTRMLKEILKIDGSGTLDHKSEMKQFGNEVTVSSNRRDEYGSSSQPKQNKKLTSYTNKPHSASEYHNVQSLDSMCWPALSQIPPVSTPVTELSRICSLVGMPQPDFSFLRTPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGVNFPLPPPIFPSYPPAVPPGTIPPVFPQPTANIMPSSTHLFGSMPWGPPVPVPGKPFHHTSYAGTMPMAGGMPAGVHNQFIPLQVTKKRVANKKNFENKETQSSHATPLQTSQSASSDVTKAVPQESSSASLKSSQNIQPASSLQAEAASPGHSMSHHKSTPSSSSRRKSRKLAVNFGISKPSE", "length": 1691, "header": "tr|A0A5G2RBD4-1|A0A5G2RBD4_PIG Computationally mapped isoform of 5'-3' exoribonuclease 1 OS=Sus scrofa OX=9823 GN=XRN1 PE=3 SV=1 CANONICAL=A0A5G2QSC5-1" }, "locus": { "chromosome": "13", "start_pos": 83174402, "end_pos": 83068937, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082815.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082815.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071476.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071476.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-450385", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450385", "resource": "Reactome", "description": "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" }, { "id": "R-SSC-450513", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450513", "resource": "Reactome", "description": "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "pmid": "" }, { "name": "histone mRNA catabolic process", "id": "GO:0071044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071044", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "pmid": "" }, { "name": "5'-3' RNA exonuclease activity", "id": "GO:0004534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004534", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "pmid": "" }, { "name": "telomerase RNA binding", "id": "GO:0070034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070034", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1114, "end_pos": 1116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1170, "end_pos": 1172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1200, "end_pos": 1202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1212, "end_pos": 1214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1270, "end_pos": 1272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-450431", "name": "ZFP36 (TTP) recruits RNA degradation activities", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-450431", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450431" } ] }, { "id": "R-SSC-450488", "name": "BRF1 Complex recruits RNA degradation activities", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-450488", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450488" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" }, { "id": "PF18332", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18332" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "5'-3' exoribonuclease 1 D1", "eco_id": "ECO_0000259", "start_pos": 654, "end_pos": 843, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QSC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" }, { "id": "PF18129", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18129" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "5'-3' exoribonuclease 1 SH3-like", "eco_id": "ECO_0000259", "start_pos": 1101, "end_pos": 1170, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QSC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" }, { "id": "PF18334", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18334" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exoribonuclease Xrn1 D2/D3", "eco_id": "ECO_0000259", "start_pos": 849, "end_pos": 1074, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QSC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" }, { "id": "PF03159", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Xrn1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 227, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QSC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC5" }, { "id": "PF17846", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17846" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Xrn1 helical", "eco_id": "ECO_0000259", "start_pos": 272, "end_pos": 597, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1114, "end_pos": 1116 }, { "start_pos": 1170, "end_pos": 1172 }, { "start_pos": 1200, "end_pos": 1202 }, { "start_pos": 1212, "end_pos": 1214 }, { "start_pos": 1270, "end_pos": 1272 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 768, "end_pos": 770 }, { "start_pos": 789, "end_pos": 791 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSC8-1", "uniprot_ac": "A0A5G2QSC8", "uniprot_id": "A0A5G2QSC8_PIG", "mass": { "chemical_mass": 18667.0, "monoisotopic_mass": 18667.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Nucleoside-diphosphate kinase", "type": "recommended", "evidence": [ { "id": "A0A5G2QSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QSC8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00406", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00406", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QSC8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSCCGCRLLHVLGLSFLLLTRWPLFLCPHRLTRPKVGFVLGGPSTDKGTQREMDQTMAAKELQKNKFLIDGFPRNQDNLQGWNKIMDEKANVSFFLFFDCNNEICIDPCLERGKSSSGSDDNKESLEKRIQTYLQSTKPITDFYEDMGEVKKMVVKIFDKEG", "length": 163, "header": "tr|A0A5G2QSC8-1|A0A5G2QSC8_PIG Isoform 1 of Nucleoside-diphosphate kinase OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A5G2QSC8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC8/entry#A0A5G2QSC8-1", "sequence": { "sequence": "MLSCCGCRLLHVLGLSFLLLTRWPLFLCPHRLTRPKVGFVLGGPSTDKGTQREMDQTMAAKELQKNKFLIDGFPRNQDNLQGWNKIMDEKANVSFFLFFDCNNEICIDPCLERGKSSSGSDDNKESLEKRIQTYLQSTKPITDFYEDMGEVKKMVVKIFDKEG", "length": 163, "header": "tr|A0A5G2QSC8-1|A0A5G2QSC8_PIG Isoform 1 of Nucleoside-diphosphate kinase OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A5G2QSC8-1" }, "locus": { "chromosome": "14", "start_pos": 134540006, "end_pos": 134539044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084548.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084548.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067717.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067717.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC8" } ], "pmid": "" }, { "name": "nucleobase-containing compound kinase activity", "id": "GO:0019205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019205", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSC8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSC8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 163, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSC8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSC8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSE8-1", "uniprot_ac": "A0A5G2QSE8", "uniprot_id": "A0A5G2QSE8_PIG", "mass": { "chemical_mass": 65138.0, "monoisotopic_mass": 65138.0 }, "refseq": { "ac": "XP_001929315", "name": "keratin, type II cytoskeletal 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929315" }, "gene_names": [ { "name": "KRT3", "type": "recommended", "evidence": [ { "id": "A0A5G2QSE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8" } ] }, { "name": "KRT3", "type": "synonym", "evidence": [ { "id": "XP_001929315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929315" } ] } ], "protein_names": [ { "name": "Keratin 3", "type": "synonym", "evidence": [ { "id": "A0A5G2QSE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8/entry#names_and_taxonomy" } ] }, { "name": "keratin, type II cytoskeletal 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001929315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929315" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSE8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KRT3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8", "locus": { "chromosome": "5", "start_pos": 18075864, "end_pos": 18082196, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000023254", "url": "https://www.ensembl.org/id/ENSSSCG00000023254" } ] } } ], "crossref": [ { "id": "A0A5G2QSE8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSE8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000023254", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000023254", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100157304", "url": "https://www.ncbi.nlm.nih.gov/gene/100157304", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157304", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157304", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XLGELQT", "url": "https://omabrowser.org/oma/group/XLGELQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QSE8", "url": "https://www.orthodb.org/?gene=A0A5G2QSE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001929315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929315", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QSE8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LDM6", "url": "https://www.uniprot.org/uniprotkb/I3LDM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LDM6-1", "url": "https://www.uniprot.org/uniprotkb/I3LDM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRQVCKTSGGRSQGFSGHSAVISGSSRMSCVARTRGAGGGACGFQSGAGGFGSRSLYNLGGNKSISISVAGGSRAGGFGGGRSSCISGFGGGYGGGFGGGFGGGRGMGGGFGGAGGFGGVGGFGGAGGFGGAGGFGGAGGFGGAGGFGGPGGFGGPGGFGGPGGFGPGGFPGGIQEVTVNQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTNSITGTNNLEPLFENYINSQRSYLDSILGEKGRLDSELRNMQDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKVDALRDEINFLTTLYEMELSQMQSHVSDTSVVLSMDNNRFLDLDSIIAEVKAQYEEIAQRSKAEAEALYQTKLGELQTTAGRHGDDLKSTKSEISELNRLIQRLRAEIENVKKQSAKLQTAVADAEQRGEMALKDANAKLQELRAALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGECQSAVSISVVSSSSTTSASAGGYGGGFGGGIGVGGGAGGGFGGAGGSGLGGGSGFGGGSGLGGGSGFGGGSGFGGGSGFGGSGGFGSGSAGRCGVSGGGFSSGSSSRGGSVKFSQSSQRSSR", "length": 643, "header": "tr|A0A5G2QSE8-1|A0A5G2QSE8_PIG Isoform 1 of Keratin 3 OS=Sus scrofa OX=9823 GN=KRT3 PE=1 SV=1 CANONICAL=A0A5G2QSE8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8/entry#A0A5G2QSE8-1", "sequence": { "sequence": "MSRQVCKTSGGRSQGFSGHSAVISGSSRMSCVARTRGAGGGACGFQSGAGGFGSRSLYNLGGNKSISISVAGGSRAGGFGGGRSSCISGFGGGYGGGFGGGFGGGRGMGGGFGGAGGFGGVGGFGGAGGFGGAGGFGGAGGFGGAGGFGGPGGFGGPGGFGGPGGFGPGGFPGGIQEVTVNQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTNSITGTNNLEPLFENYINSQRSYLDSILGEKGRLDSELRNMQDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKVDALRDEINFLTTLYEMELSQMQSHVSDTSVVLSMDNNRFLDLDSIIAEVKAQYEEIAQRSKAEAEALYQTKLGELQTTAGRHGDDLKSTKSEISELNRLIQRLRAEIENVKKQSAKLQTAVADAEQRGEMALKDANAKLQELRAALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGECQSAVSISVVSSSSTTSASAGGYGGGFGGGIGVGGGAGGGFGGAGGSGLGGGSGFGGGSGLGGGSGFGGGSGFGGGSGFGGSGGFGSGSAGRCGVSGGGFSSGSSSRGGSVKFSQSSQRSSR", "length": 643, "header": "tr|A0A5G2QSE8-1|A0A5G2QSE8_PIG Isoform 1 of Keratin 3 OS=Sus scrofa OX=9823 GN=KRT3 PE=1 SV=1 CANONICAL=A0A5G2QSE8-1" }, "locus": { "chromosome": "5", "start_pos": 18082119, "end_pos": 18076226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082564.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082564.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061118.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061118.1" } ] } }, { "isoform_ac": "A0A8W4FDW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8/entry#A0A8W4FDW0-1", "sequence": { "sequence": "MSRQVCKTSGGRSQGFSGHSAVISGSSRMSCVARTRGAGGGACGFQSGAGGFGSRSLYNLGGNKSISISVAGGSRAGGFGGGRSSCISGFGGGYGGGFGGGFGGGRGMGGGFGGAGGFGGVGGFGGAGGFGGAGGFGGAGGFGGAGGFGGPGGFGGPGGFGGPGGFGPGGFPGGIQEVTVNQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTNSITGTNNLEPLFENYINSQRSYLDSILGEKGRLDSELRNMQDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKVDALRDEINFLTTLYEMELSQMQSHVSDTSVVLSMDNNRFLDLDSIIAEVKAQYEEIAQRSKAEAEALYQTKLGELQTTAGRHGDDLKSTKSEISELNRLIQRLRAEIENVKKQSAKLQTAVADAEQRGEMALKDANAKLQELRAALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRWASTSIPSPPPTQLLCSFGYGWTPSLGTSICLRCGPKKTKKKKFFSGQRGLLGLEGVADMFL", "length": 579, "header": "tr|A0A8W4FDW0-1|A0A5G2QSE8_PIG Computationally mapped isoform of Keratin 3 OS=Sus scrofa OX=9823 GN=KRT3 PE=1 SV=1 CANONICAL=A0A5G2QSE8-1" }, "locus": { "chromosome": "5", "start_pos": 18082119, "end_pos": 18076885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104455.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104455.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076495.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076495.1" } ] } }, { "isoform_ac": "I3LDM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8/entry#I3LDM6-1", "sequence": { "sequence": "MSRQVCKTSGGRSQGFSGHSAVISGSSRMSCVARTRGAGGGACGFQSGAGGFGSRSLYNLGGNKSISISVAGGSRAGGFGGGRSSCISGFGGGYGGGFGGGFGGGRGMGGGFGGAGGFGGVGGFGGAGGFGGAGGFGGAGGFGGAGGFGGPGGFGGPGGFGGPGGFGPGGFPGGIQEVTVNQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTNSITGTNNLEPLFENYINSQRSYLDSILGEKGRLDSELRNMQDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKVDALRDEINFLTTLYEMELSQMQSHVSDTSVVLSMDNNRFLDLDSIIAEVKAQYEEIAQRSKAEAEALYQTKLGELQTTAGRHGDDLKSTKSEISELNRLIQRLRAEIENVKKQSAKLQTAVADAEQRGEMALKDANAKLQELRAALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEESDRCTVLSPAAVVSSSSTTSASAGGYGGGFGGGIGVGGGAGGGFGGAGGSGLGGGSGFGGGSGLGGGSGFGGGSGFGGGSGFGGSGGFGSGSAGRCGVSGGGFSSGSSSRGGSVKFSQSSQRSSR", "length": 640, "header": "tr|I3LDM6-1|A0A5G2QSE8_PIG Computationally mapped isoform of Keratin 3 OS=Sus scrofa OX=9823 GN=KRT3 PE=1 SV=2 CANONICAL=A0A5G2QSE8-1" }, "locus": { "chromosome": "5", "start_pos": 18082119, "end_pos": 18076226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025193.3", "url": "https://www.ensembl.org/id/ENSSSCT00000025193.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022158.2", "url": "https://www.ensembl.org/id/ENSSSCP00000022158.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LDM6", "url": "https://www.uniprot.org/uniprotkb/I3LDM6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157304", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157304", "resource": "KEGG Pathway" }, { "id": "R-SSC-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-SSC-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MYR8-1", "protein_name": "Keratin 3", "gene_name": "KRT3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNRQVRKTSGSGSQGFSGRSAVVSGSSRMSCVARSGGGGGGAFGFRSGAGGFGSRSLYNLGGNKSISISVAGSRAGGFGGGRSSCVSGFGSGYGGGYGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGLGGFGGPGGFGPGGFGPGGFPGGIQEVTVNQSLLQPLNVEIDPQIGQVKTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWSLLQQQGTHPITGTNNLEPLFENYINSLRSYLDSILGERGRLDSELRNMQDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKVDALTDEINFLTTLYDMELSQMQSHVSDTSVVLSMDNNRSLDLDSIIAEVKAQYEEIAQRSKAEAEALYQTKLGELQTTAGRHGDDLKSTKSEISELNRVIQRLRAEIENVKKQIAKLQSAIAEAEQRGELALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRWASYSVVSSSSTTSASAGGFGGGYGGGVGVGGGARSGFGGGSGFGGGSGFGGGSGFGGGSGISGSSGFGGGSGSGFGGGSGFSGSSGFGGGSSGFGSGSGGRSGVSGGGLSSGSSRGGSVRFSQSSQRTSR", "length": 628 }, "evidence": [ { "id": "A0A5G2QSE8", "url": "https://omabrowser.org/oma/group/A0A5G2QSE8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P12035-1", "protein_name": "Keratin, type II cytoskeletal 3", "gene_name": "KRT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYGVSGGGFSSASNRGGSIKFSQSSQSSQRYSR", "length": 628 }, "evidence": [ { "id": "A0A5G2QSE8", "url": "https://omabrowser.org/oma/group/A0A5G2QSE8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSE8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSE8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "keratinization", "id": "GO:0031424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSE8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSE8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSE8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSE8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 643, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSE8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSE8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSE8" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 518, "start_aa": "Glu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSG3-1", "uniprot_ac": "A0A5G2QSG3", "uniprot_id": "A0A5G2QSG3_PIG", "mass": { "chemical_mass": 34448.0, "monoisotopic_mass": 34448.0 }, "refseq": { "ac": "XP_003122836", "name": "olfactory receptor 4X2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122836" }, "gene_names": [ { "name": "LOC100523167", "type": "recommended", "evidence": [ { "id": "A0A5G2QSG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3" } ] }, { "name": "LOC100523167", "type": "synonym", "evidence": [ { "id": "XP_003122836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122836" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QSG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4X2-like", "type": "synonym", "evidence": [ { "id": "XP_003122836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122836" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100523167", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3", "locus": {} } ], "crossref": [ { "id": "A0A5G2QSG3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000049702", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000049702", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523167", "url": "https://www.ncbi.nlm.nih.gov/gene/100523167", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523167", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523167", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WVGAFVH", "url": "https://omabrowser.org/oma/group/WVGAFVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QSG3", "url": "https://www.orthodb.org/?gene=A0A5G2QSG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003122836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QSG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANTHNVTEFIFLGLFPNLKVQKVCFVIFLLLYTAIVLGNFIIVLTVMTSRSLGSPMYFFLSSLSFVEICYSSTTTPKLISDLLADRKAISLWGCMSQVFFIHFFGGVEMFLLTVMAYDRYVAICKPLNYITIMNRQVCAFLVGVAGAGGFVHSSAQILLIFRLPFCGPNVIDHYFCDVLPLLKLACSDTFLIGLLMVANGGTLSVVSFLVLLVSYAVILLHLRTQSSEGRRKALSTCGSHIAVVTLFFGPCLFIYLRPSTILPVDKVVAVFYTVITPLLNPVIYSLRNAEMKKAVKRLWIRTVKLEEK", "length": 309, "header": "tr|A0A5G2QSG3-1|A0A5G2QSG3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100523167 PE=3 SV=1 CANONICAL=A0A5G2QSG3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3/entry#A0A5G2QSG3-1", "sequence": { "sequence": "MANTHNVTEFIFLGLFPNLKVQKVCFVIFLLLYTAIVLGNFIIVLTVMTSRSLGSPMYFFLSSLSFVEICYSSTTTPKLISDLLADRKAISLWGCMSQVFFIHFFGGVEMFLLTVMAYDRYVAICKPLNYITIMNRQVCAFLVGVAGAGGFVHSSAQILLIFRLPFCGPNVIDHYFCDVLPLLKLACSDTFLIGLLMVANGGTLSVVSFLVLLVSYAVILLHLRTQSSEGRRKALSTCGSHIAVVTLFFGPCLFIYLRPSTILPVDKVVAVFYTVITPLLNPVIYSLRNAEMKKAVKRLWIRTVKLEEK", "length": 309, "header": "tr|A0A5G2QSG3-1|A0A5G2QSG3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100523167 PE=3 SV=1 CANONICAL=A0A5G2QSG3-1" }, "locus": { "chromosome": "2", "start_pos": 14445165, "end_pos": 14444239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089801.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089801.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067757.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067757.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523167", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523167", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SY50-1", "protein_name": "Olfactory receptor family 4 subfamily X member 17", "gene_name": "OR4S1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGAKNNLTEFVLLGLFRSQEMQRACFLVFSLFHVLTVLGNLLVIVTINASKTLHAPMYFFLCHLSFADMCYPSASTPKMIADTLVERKTISFKGCMTQLFSAHFFGGTEIFLLTAMAYDRYVAICRPLHYETIMGRRKCGLLAGASWVAGFLHSILQTLLTVQLPFCGPNEIDSFFCDVHPLLKLACADTYVVGLIVVANSGMISLVSFIILIISYVVILLNLRSRSSESQRKALSTCGSHIIAVLLVLVPPMFMYIRPSTTLAADKLVILFNIVMPPLLNPLIYTLRNSEFCQENALVIANTLFQQYTWTSSDDQHQNQIDYILCSQRWRSSIQSTKTGPGADYGSDHELLIAKFRLKLKKIGKTNRPFRYDLNQIPYDYTVEVRNRFKGLDLIDRVPDELWTEVCDIVQETGIKTIPMEKKCKKARWLSGEALQIAVKRREAKSKGEKERYKHLNVEFQRIARKAKKAFLSDQCKEIEENNRMGKTRDLFKKIRDTKGTFHAKMGSIKDRNGMDLTEAEDIKKRWQEYTEELYKKDLHDPDNHDGVITHLEPDILECEVKWALESITNKASGGDGIPVELFQILKDDAVKVLHSICQKIWKPQQWPQDWKRSPIEIPASWWLHHG", "length": 627 }, "evidence": [ { "id": "A0A5G2QSG3", "url": "https://omabrowser.org/oma/group/A0A5G2QSG3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSG3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSG3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSG3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSG9-1", "uniprot_ac": "A0A5G2QSG9", "uniprot_id": "A0A5G2QSG9_PIG", "mass": { "chemical_mass": 53526.0, "monoisotopic_mass": 53526.0 }, "refseq": {}, "gene_names": [ { "name": "PDHX", "type": "recommended", "evidence": [ { "id": "A0A5G2QSG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9" } ] } ], "protein_names": [ { "name": "Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex", "type": "recommended", "evidence": [ { "id": "A0A5G2QSG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.-", "type": "synonym", "evidence": [ { "id": "A0A5G2QSG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PDHX", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9", "locus": { "chromosome": "2", "start_pos": 26014970, "end_pos": 26103402, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013298", "url": "https://www.ensembl.org/id/ENSSSCG00000013298" } ] } } ], "crossref": [ { "id": "A0A5G2QSG9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSG9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013298", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013298", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06849", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06849", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TIKQKPW", "url": "https://omabrowser.org/oma/group/TIKQKPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23151:SF90", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23151:SF90", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00364", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00364", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02817", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02817", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-204174", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204174", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5362517", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5362517", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9861559", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9861559", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QSG9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX27-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SGT3", "url": "https://www.uniprot.org/uniprotkb/F1SGT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SGT3-1", "url": "https://www.uniprot.org/uniprotkb/F1SGT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASWRLGCDPRVMRCLLGFGNCPGLVKGAAGWSLGRGASWRWYHSTQSLWADPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVAEGSKNVRLGSLIGLLVEEGEDWKHVEIPKDVGPPSPVKPSVPPPPSPQPQISTPVKKHTPGKLQFRLSPAARNILEKHALDANQGTATGPRGIFTKEDALKLVQLKEMGKITESRPSPALPTTPTAPLPPQATATPSYPRPMIPPVSIPGQPNVAGTFTEIPASNIRRVIAKRLTESKSTIPHAYATADCDLGAVLKVRQNLARDDIKVSVNDFIIKAAAVTLKQMPNVNASWDGEGPKQLPFIDISVAVATDKGLITPIIKDAAAKGLQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTQDEEGNAKLQQHQLITVTMSSDSRVVDDELATRFLESFKANLENPFRLA", "length": 498, "header": "tr|A0A5G2QSG9-1|A0A5G2QSG9_PIG Isoform 1 of Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex OS=Sus scrofa OX=9823 GN=PDHX PE=1 SV=1 CANONICAL=A0A5G2QSG9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9/entry#A0A5G2QSG9-1", "sequence": { "sequence": "MAASWRLGCDPRVMRCLLGFGNCPGLVKGAAGWSLGRGASWRWYHSTQSLWADPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVAEGSKNVRLGSLIGLLVEEGEDWKHVEIPKDVGPPSPVKPSVPPPPSPQPQISTPVKKHTPGKLQFRLSPAARNILEKHALDANQGTATGPRGIFTKEDALKLVQLKEMGKITESRPSPALPTTPTAPLPPQATATPSYPRPMIPPVSIPGQPNVAGTFTEIPASNIRRVIAKRLTESKSTIPHAYATADCDLGAVLKVRQNLARDDIKVSVNDFIIKAAAVTLKQMPNVNASWDGEGPKQLPFIDISVAVATDKGLITPIIKDAAAKGLQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTQDEEGNAKLQQHQLITVTMSSDSRVVDDELATRFLESFKANLENPFRLA", "length": 498, "header": "tr|A0A5G2QSG9-1|A0A5G2QSG9_PIG Isoform 1 of Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex OS=Sus scrofa OX=9823 GN=PDHX PE=1 SV=1 CANONICAL=A0A5G2QSG9-1" }, "locus": { "chromosome": "2", "start_pos": 26094846, "end_pos": 26015860, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074697.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074697.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067070.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067070.1" } ] } }, { "isoform_ac": "A0A5G2QX27-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9/entry#A0A5G2QX27-1", "sequence": { "sequence": "MAASWRLGCDPRVMRCLLGFGNCPGLVKGAAGWSLGRGASWRWYHSTQSLWADPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVQMPNVNASWDGEGPKQLPFIDISVAVATDKGLITPIIKDAAAKGLQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTQDEEGNAKLQQHQLITVTMSSDSRVVDDELATRFLESFKANLENPFRLA", "length": 272, "header": "tr|A0A5G2QX27-1|A0A5G2QX27_PIG Computationally mapped isoform of Pyruvate dehydrogenase complex component X OS=Sus scrofa OX=9823 GN=PDHX PE=1 SV=1 CANONICAL=A0A5G2QSG9-1" }, "locus": { "chromosome": "2", "start_pos": 26094846, "end_pos": 26015860, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070147.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070147.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069494.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069494.1" } ] } }, { "isoform_ac": "F1SGT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9/entry#F1SGT3-1", "sequence": { "sequence": "MAASWRLGCDPRVMRCLLGFGNCPGLVKGAAGWSLGRGASWRWYHSTQSLWADPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVAEGSKNVRLGSLIGLLVEEGEDWKHVEIPKDVGPPSPVQNHQFRLSPAARNILEKHALDANQGTATGPRGIFTKEDALKLVQLKEMGKITESRPSPALPTTPTAPLPPQATATPSYPRPMIPPVSIPGQPNVAGTFTEIPASNIRRVIAKRLTESKSTIPHAYATADCDLGAVLKVRQNLARDDIKVSVNDFIIKAAAVTLKQMPNVNASWDGEGPKQLPFIDISVAVATDKGLITPIIKDAAAKGLQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTQDEEGNAKLQQHQLITVTMSSDSRVVDDELATRFLESFKANLENPFRLA", "length": 475, "header": "tr|F1SGT3-1|F1SGT3_PIG Computationally mapped isoform of Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex OS=Sus scrofa OX=9823 GN=PDHX PE=1 SV=2 CANONICAL=A0A5G2QSG9-1" }, "locus": { "chromosome": "2", "start_pos": 26094846, "end_pos": 26015860, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014524.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014524.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014131.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014131.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 249, "start_aa": "Thr", "end_pos": 249, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr249", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-204174", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204174", "resource": "Reactome", "description": "Regulation of pyruvate dehydrogenase (PDH) complex" }, { "id": "R-SSC-5362517", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5362517", "resource": "Reactome", "description": "Signaling by Retinoic Acid" }, { "id": "R-SSC-9861559", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9861559", "resource": "Reactome", "description": "PDH complex synthesizes acetyl-CoA from PYR" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZH8-1", "protein_name": "Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex", "gene_name": "Pdhx", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASWRLRCNLPLVRYFLGFGSGRSLGLSQGAAAWTVGRGANWRWFHGTQLLQADPIKILMPSLSPTMERGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDANDDGILAKIVVEEGAKNIKLGSLIALMVEEGEDWKHVEIPKDVSAPPPVPKPPAPPQPSPQTQTPCPARKERTVGTPPRLRLSPAARNILEKHSLDASQGTATGPRGVFTKEDALRLVELKQMGKIAEFRPAPGPPSTLSAPVPPQPTAGLSYPRPMIPPVSIPGQPNAAGTFTEIPASNIRKVIAKRLTESKSTVPHAYATANCDLGAVLKVRRDLVKDDIKVSVNDFIIRAAAVTLKQMPGVNVTWDGEGPKHLPSVDISVAVATDKGLITPIIKDAAAKDIREIADAVKVLSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNPQVRQHQLITVTMSSDSRMVDDELATKFLETFKANLENPMRLA", "length": 503 }, "evidence": [ { "id": "A0A5G2QSG9", "url": "https://omabrowser.org/oma/group/A0A5G2QSG9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1A102-1", "protein_name": "Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex", "gene_name": "PDHX", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAASWWRSGGAGVLRLLRGGRPVLSAGLAVPARGGWRFLHGTQELLGTPAIKVLMPALSPTMEEGNIVKWLKKEGEMVNAGDALCEIETDKAVVTMESSDDGILAKILVEEGSKNVRLGSLIGLLVEEGQDWKQVEIPADANDQSSLAPPAAAVTSTPAGPSVSAPPKVEHQPGKLQFRLSPAARNIVETHGLDPSSVTPSGPRGIFTKEDALKLLQGKQKDKPSELKPVVSPATPQPTAVPSALPAAAVPSAYPRPIVPPVSTPGQPAAPGTFTEIPASNIRRVIAKRLTESKTTIPHAYAAADCDIDAILKLRSELAKDDIKVSVNDFIIKAAAVTLKQMPDVNATWDGEGCRQLQSIDISIAVATDRGLITPIIKDVPAKGIQEIAASAKALAKKARDGKLLPEEYQGGSFSISNLGMFGINDFIAVINPPQACILAVGRARPELKIVEDEEGNEKLKQHQLMTVTLSSDGRVVNDELASKFLETFKANIENPIRLALC", "length": 502 }, "evidence": [ { "id": "A0A5G2QSG9", "url": "https://omabrowser.org/oma/group/A0A5G2QSG9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1R0J8-1", "protein_name": "Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex", "gene_name": "pdhx", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAASMRLGRRTLFTALRALTQTPAGLQSSFRPPRESPRPAGWSRSAARPLYQSCRARAGVCPLKVQMPALSPTMEEGNIVKWLKKEGEDVAAGDALCEIETDKAVVVMESNEDGVLARILVQEGSRGVRLGTLIALMVSEGEDWKQVEIPALESVTPPTAAPPTAAPPTAGSAPPAAPALRQSVPTPLLRLSPAARHILDTHGLDPHQATASGPRGIITKEDALKLLSKASAAPPAAAAPAPSAPPAAPPAARPPHPPASAPARSAAPGTFTEIPASSVRRIIAQRLTQSKTTIPHTYACIHCDISGVMRVRKRLAEENIKVSVNDFIIKAAAVSLRELPAVNVSWSADGPQPLGFIHISMAVATDRGLITPIIRDAADKGLQEISSTAKALAQKARDGKLLPEEYQGGSFSVSNLGMFGISEFSAVINPPQACILAVGGSRTELSLSAEDTLQTQHTLTVTLSSDARLVDDELASRFLETFRSNLERPERMSLQA", "length": 496 }, "evidence": [ { "id": "A0A5G2QSG9", "url": "https://omabrowser.org/oma/group/A0A5G2QSG9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O00330-1", "protein_name": "Pyruvate dehydrogenase protein X component, mitochondrial", "gene_name": "PDHX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASWRLGCDPRLLRYLVGFPGRRSVGLVKGALGWSVSRGANWRWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENPIRLA", "length": 501 }, "evidence": [ { "id": "A0A5G2QSG9", "url": "https://omabrowser.org/oma/group/A0A5G2QSG9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P22439-1", "protein_name": "Pyruvate dehydrogenase protein X component", "gene_name": "PDHX", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAASWRLGCDPRLLRCLLGFGSRRSPELVKGAARWSVGRGASWRWFHSTQWLRADPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVAEGSKNIRLGSLIGLLVEEGEDWKHVEIPKDTGPPPPAAKPSVPPPSAEPQIATPVKKEHPPGKVQFRLSPAARNILEKHALDANQGTATGPRGIFTKEDALKLVQLKQTGKITEPRPTAALPTTPAAPLPPQAAATASYPRPMIPPVSTPGQPNVEGTFTEIPASNIRRVIAKRLTESKSTIPHAYATTDCDLGAVLTARQNLVRDDIKVSVNDFIIKAAAVTLKQMPNVNASWDGEGAKQLPSIDISVAVATDRGLITPVIKDAAAKGLQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTQDEEGNAQLQQRQLITVTMSSDSRVVDDELATRFLESFKANLENPLRLA", "length": 501 }, "evidence": [ { "id": "A0A5G2QSG9", "url": "https://omabrowser.org/oma/group/A0A5G2QSG9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q0WQF7-1", "protein_name": "Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial", "gene_name": "LTA3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLPLFRRAAIARTSSLLRARLFAPASEFHSRFSNGLYHLDDKISSSNGVRSASIDLITRMDDSSPKPILRFGVQNFSSTGPISQTVLAMPALSPTMSHGNVVKWMKKEGDKVEVGDVLCEIETDKATVEFESQEEGFLAKILVTEGSKDIPVNEPIAIMVEEEDDIKNVPATIEGGRDGKEETSAHQVMKPDESTQQKSSIQPDASDLPPHVVLEMPALSPTMNQGNIAKWWKKEGDKIEVGDVIGEIETDKATLEFESLEEGYLAKILIPEGSKDVAVGKPIALIVEDAESIEAIKSSSAGSSEVDTVKEVPDSVVDKPTERKAGFTKISPAAKLLILEHGLEASSIEASGPYGTLLKSDVVAAIASGKASKSSASTKKKQPSKETPSKSSSTSKPSVTQSDNNYEDFPNSQIRKIIAKRLLESKQKIPHLYLQSDVVLDPLLAFRKELQENHGVKVSVNDIVIKAVAVALRNVRQANAFWDAEKGDIVMCDSVDISIAVATEKGLMTPIIKNADQKSISAISLEVKELAQKARSGKLAPHEFQGGTFSISNLGMYPVDNFCAIINPPQAGILAVGRGNKVVEPVIGLDGIEKPSVVTKMNVTLSADHRIFDGQVGASFMSELRSNFEDVRRLLL", "length": 637 }, "evidence": [ { "id": "A0A5G2QSG9", "url": "https://omabrowser.org/oma/group/A0A5G2QSG9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8BKZ9-1", "protein_name": "Pyruvate dehydrogenase protein X component, mitochondrial", "gene_name": "Pdhx", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASWRLHCNQPLLRYLLGFSSRRSLGLAQGAAAWPVDRGASWRWFHSTQLLQADPIKVLMPSLSPTMEQGNIVKWLRKEGEAVSAGDSLCEIETDKAVVTLDANDDGILAKIVVEEGAKNIQLGSLIALMVEEGEDWKQVEIPKDVSAPPPVSKPPAPTQPSPQPQIPCPARKEHKGTARFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVELKQMGKITESRPASAPPPSLSASVPPQATAGPSYPRPMTPPVSIPGQPNAAGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRRDLVKDDIKVSVNDFIIRAAAVTLKQMPGVNVTWDGEGPKQLPSVDISVAVATDKGLITPIIKDAAAKGIQEIADSVKVLSKKARDGKLMPEEYQGGSFSISNLGMFGIDEFAAVINPPQACILAVGRFRPVLKLTEDEEGNPQLQQHQLITVTMSSDSRVVDDELATRFLETFKANLENPMRLG", "length": 501 }, "evidence": [ { "id": "A0A5G2QSG9", "url": "https://omabrowser.org/oma/group/A0A5G2QSG9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9" } ], "pmid": "" }, { "name": "pyruvate dehydrogenase complex", "id": "GO:0045254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045254", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "pyruvate decarboxylation to acetyl-CoA", "id": "GO:0006086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006086", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "dihydrolipoyllysine-residue acetyltransferase activity", "id": "GO:0004742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004742", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9" } ], "pmid": "" }, { "name": "acyltransferase activity", "id": "GO:0016746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016746", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSG9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-203946", "name": "PDK isozymes phosphorylate PDHC subunit E1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-203946", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-203946" } ] }, { "id": "R-SSC-204169", "name": "PDP1,2 dephosphorylate p-lipo-PDH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-204169", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204169" } ] }, { "id": "R-SSC-9861616", "name": "DLD dimer dehydrogenates dihydrolipoyl", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-SSC-9861664" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9861616", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9861616" } ] }, { "id": "R-SSC-9861667", "name": "DLAT trimer transfers acetyl to CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9861667", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9861667" } ] }, { "id": "R-SSC-9861734", "name": "PDH E1 decarboxylates PYR, transferring acetyl to DLAT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-SSC-69969" ], "output_participant_list": [ "R-SSC-9861594" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9861734", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9861734" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-69969", "participant_name": "DLAT [mitochondrial matrix]", "crossref": [ { "id": "A0A5G2QLQ1", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000015030", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000063005", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000078875", "database": "ENSEMBL", "url": "" }, { "id": "9J1W", "database": "PDB", "url": "" }, { "id": "87325", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9861594", "participant_name": "DLAT [mitochondrial matrix]", "crossref": [ { "id": "ENSSSCP00000063005", "database": "ENSEMBL", "url": "" }, { "id": "A0A5G2QLQ1", "database": "UniProt", "url": "" }, { "id": "9J1W", "database": "PDB", "url": "" }, { "id": "87325", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000078875", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000015030", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9861664", "participant_name": "DLAT [mitochondrial matrix]", "crossref": [ { "id": "A0A5G2QLQ1", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000015030", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000063005", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000078875", "database": "ENSEMBL", "url": "" }, { "id": "9J1W", "database": "PDB", "url": "" }, { "id": "87325", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSG9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 498, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSG9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSG9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9" }, { "id": "PS50968", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50968" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipoyl-binding", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 130, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QSG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSG9" }, { "id": "PS51826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peripheral subunit-binding (PSBD)", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 217, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 249 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 344, "end_pos": 346 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSK6-1", "uniprot_ac": "A0A5G2QSK6", "uniprot_id": "A0A5G2QSK6_PIG", "mass": { "chemical_mass": 35526.0, "monoisotopic_mass": 35526.0 }, "refseq": { "ac": "XP_020919610", "name": "olfactory receptor 6M1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919610" }, "gene_names": [ { "name": "LOC100524388", "type": "synonym", "evidence": [ { "id": "XP_020919610", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919610" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QSK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK6/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6M1-like", "type": "synonym", "evidence": [ { "id": "XP_020919610", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919610" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK6", "locus": {} } ], "crossref": [ { "id": "A0A5G2QSK6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000048275", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000048275", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524388", "url": "https://www.ncbi.nlm.nih.gov/gene/100524388", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524388", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524388", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CYNEIHH", "url": "https://omabrowser.org/oma/group/CYNEIHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QSK6", "url": "https://www.orthodb.org/?gene=A0A5G2QSK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020919610", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919610", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QSK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVQNQTTVTEFILTAFPALHKLQVFLFAVLLVTYMLTLTGNGVIISLIWADNRLQTPMYFFLSNLSFLDILYTTSVTPKLLACLLEDRKTISLAGCITQTYFFFFLGTVEFILLVVMSFDRYVAICNPLRYTIIMNSRVCLLLVLGCWVGAFLSVLCPVILLSRLPFCSEEINHFFCDIAPLLQAACINTHFLEMISFLLSSLVLLTSLVLTTVSYTYIISTILRIPSAQGRQKAFSTCASHITVVSIAYGSNIFMYVRPSQNHSLEFDKVTAVLTIMGTPLLNPFIYSLRNETVKEVLRDAGNKIMSLWHQKP", "length": 315, "header": "tr|A0A5G2QSK6-1|A0A5G2QSK6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QSK6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK6/entry#A0A5G2QSK6-1", "sequence": { "sequence": "MEVQNQTTVTEFILTAFPALHKLQVFLFAVLLVTYMLTLTGNGVIISLIWADNRLQTPMYFFLSNLSFLDILYTTSVTPKLLACLLEDRKTISLAGCITQTYFFFFLGTVEFILLVVMSFDRYVAICNPLRYTIIMNSRVCLLLVLGCWVGAFLSVLCPVILLSRLPFCSEEINHFFCDIAPLLQAACINTHFLEMISFLLSSLVLLTSLVLTTVSYTYIISTILRIPSAQGRQKAFSTCASHITVVSIAYGSNIFMYVRPSQNHSLEFDKVTAVLTIMGTPLLNPFIYSLRNETVKEVLRDAGNKIMSLWHQKP", "length": 315, "header": "tr|A0A5G2QSK6-1|A0A5G2QSK6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QSK6-1" }, "locus": { "chromosome": "9", "start_pos": 50667561, "end_pos": 50666617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070662.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070662.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067915.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067915.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524388", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524388", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M5D9-1", "protein_name": "Olfactory receptor", "gene_name": "OR6M2C", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDVQNQTTVTKFILTAFPTVQKLQISLFVVLLFTYMLTLTGNGVIISLIWADYRLQTPMYFFLSNLSLLDISYTSSVTPKLLSFLLKDRKTISLAGCISQTYFFFLGTVEFILLVVMSFDRYVAICKPLRYTIIMNSRACLLLVLGCWVGAFLSVLCPVILLSRLPFCHKEINHFFCDIAPLLQVACIDTHFLEMISFLLSSLILLTSLVLTTVSYTYIISTILSIPSAQGRQKAFSTCASHITVVSIAYGSNIFMYVRPSQSHSLQFDKVTAVFTIMVTPLLNPFIYSLRNKTAKDVLRDAVNKIISSLHRKP", "length": 314 }, "evidence": [ { "id": "A0A5G2QSK6", "url": "https://omabrowser.org/oma/group/A0A5G2QSK6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSK6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 315, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSK6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSK6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 264, "end_pos": 266 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSK8-1", "uniprot_ac": "A0A5G2QSK8", "uniprot_id": "A0A5G2QSK8_PIG", "mass": { "chemical_mass": 55027.0, "monoisotopic_mass": 55027.0 }, "refseq": { "ac": "NP_001230596", "name": "solute carrier family 41 member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230596" }, "gene_names": [ { "name": "SLC41A1", "type": "recommended", "evidence": [ { "id": "A0A5G2QSK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8" } ] }, { "name": "SLC41A1", "type": "synonym", "evidence": [ { "id": "NP_001230596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230596" } ] } ], "protein_names": [ { "name": "Solute carrier family 41 member", "type": "recommended", "evidence": [ { "id": "A0A5G2QSK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 41 member 1", "type": "synonym", "evidence": [ { "id": "NP_001230596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230596" } ] } ], "function": [ { "annotation": "Acts as a magnesium transporter.", "evidence": [ { "database": "UniProtKB", "id": "I3LE64", "url": "https://www.uniprot.org/uniprotkb/I3LE64#function" }, { "database": "UniProtKB", "id": "RU369007", "url": "https://www.uniprot.org/uniprotkb/RU369007#function" }, { "database": "UniProtKB", "id": "A0A5G2QSK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC41A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8", "locus": { "chromosome": "9", "start_pos": 66473341, "end_pos": 66499805, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000020783", "url": "https://www.ensembl.org/id/ENSSSCG00000020783" } ] } } ], "crossref": [ { "id": "ENSSSCG00000020783", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000020783", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100626641", "url": "https://www.ncbi.nlm.nih.gov/gene/100626641", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006667", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006667", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626641", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626641", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDPDNVT", "url": "https://omabrowser.org/oma/group/WDPDNVT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QSK8", "url": "https://www.orthodb.org/?gene=A0A5G2QSK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16228:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16228:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01769", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01769", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-425410", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-425410", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230596", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230596", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QSK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LE64", "url": "https://www.uniprot.org/uniprotkb/I3LE64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LE64-1", "url": "https://www.uniprot.org/uniprotkb/I3LE64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSKPEPKDTHQLNGTGPTASPCSSDGPGREPMAGTSEFLGPDGAGVEVVVIESRANAKGVREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYQEQDVWQYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEQVPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD", "length": 514, "header": "tr|A0A5G2QSK8-1|A0A5G2QSK8_PIG Isoform 1 of Solute carrier family 41 member OS=Sus scrofa OX=9823 GN=SLC41A1 PE=3 SV=1 CANONICAL=A0A5G2QSK8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8/entry#A0A5G2QSK8-1", "sequence": { "sequence": "MSSKPEPKDTHQLNGTGPTASPCSSDGPGREPMAGTSEFLGPDGAGVEVVVIESRANAKGVREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYQEQDVWQYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEQVPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD", "length": 514, "header": "tr|A0A5G2QSK8-1|A0A5G2QSK8_PIG Isoform 1 of Solute carrier family 41 member OS=Sus scrofa OX=9823 GN=SLC41A1 PE=3 SV=1 CANONICAL=A0A5G2QSK8-1" }, "locus": { "chromosome": "9", "start_pos": 66496889, "end_pos": 66475768, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085322.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085322.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061153.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061153.1" } ] } }, { "isoform_ac": "I3LE64-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8/entry#I3LE64-1", "sequence": { "sequence": "MSSKPEPKDTHQLNGTGPTASPCSSDGPGREPMAGTSEFLGPDGAGVEVVVIESRANAKGVREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYQEQDVWQYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEQVPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVRAVMWGAQATEYIEDAGLPTPT", "length": 476, "header": "tr|I3LE64-1|A0A5G2QSK8_PIG Computationally mapped isoform of Solute carrier family 41 member OS=Sus scrofa OX=9823 GN=SLC41A1 PE=3 SV=2 CANONICAL=A0A5G2QSK8-1" }, "locus": { "chromosome": "9", "start_pos": 66496889, "end_pos": 66476873, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028316.3", "url": "https://www.ensembl.org/id/ENSSSCT00000028316.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022350.2", "url": "https://www.ensembl.org/id/ENSSSCP00000022350.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LE64", "url": "https://www.uniprot.org/uniprotkb/I3LE64" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626641", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626641", "resource": "KEGG Pathway" }, { "id": "R-SSC-425410", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-425410", "resource": "Reactome", "description": "Metal ion SLC transporters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SR46-1", "protein_name": "Solute carrier family 41 member", "gene_name": "SLC41A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSKPEPKDAHQLNGTGPAASACSSEGPGREPLAGTSEFLGPDGAEVEVVVPESRANAKGLREEDALLENGSQSNESDDVSSDHGPAAPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATASIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLEQGIWQYIYPLVCAFFVALLPVWVMLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGTPGENSEQAPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD", "length": 514 }, "evidence": [ { "id": "A0A5G2QSK8", "url": "https://omabrowser.org/oma/group/A0A5G2QSK8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZM22-1", "protein_name": "Solute carrier family 41 member", "gene_name": "Slc41a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKPEPKDIHQPNGTGPTPSPCSSDGPGREPLAGTSEFLGPDGAGVEVVVIESRANAKGVREEDALLENGSQSNESDDVSTDRVPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGQMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELTHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEPTPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVNWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD", "length": 514 }, "evidence": [ { "id": "A0A5G2QSK8", "url": "https://omabrowser.org/oma/group/A0A5G2QSK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C334-1", "protein_name": "Solute carrier family 41 member", "gene_name": "SLC41A1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSKPEQKETHQANGAVLPAVPMDCLVSPDRGQLVEPSNFLGPDGVGVEVVVLESRANAKGVREEDALLENGSQSNESDDTSTDRGPEPASPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWDVFKYVTEVFILVPALLGLKGNLEMTLASRLSTAANIGQMDTPKELWKMITGNMALIQVQATVVGFLASIAAVIFGWIPDGHFSLDHAVLLCASSVATAFIASLVLGMIMIGVIIGSRKMGINPDNVATPIAASLGDLITLALLSGISWGLYKELESKAYVNPLVCAFFIALLPIWIIIAKKNAATREVLYSGWEPVIIAMAISSVGGLILDRTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTYLHMSGMPGESPETAPRKCPSPCSTFFSSDVNSRSARVLFLLVVPGHLVFLYTISSMQGGHTTLTPIFIVFYMTAALLQVLILLYIADWMVHWMWGRDLDPDNFSIPYLTALGDLIGTGLLALSFHVLWLIGDRDSDVGD", "length": 515 }, "evidence": [ { "id": "A0A5G2QSK8", "url": "https://omabrowser.org/oma/group/A0A5G2QSK8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7EXX2-1", "protein_name": "Solute carrier family 41 member 1", "gene_name": "slc41a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLWLKDQDKLSDMSTGTERIEMKKEGVPPAYHHSNGSVHPVILPDSPEEVPQTPGEYELTEVTSLPDCGDQENERPDMVVLDCRANAKGQREEDALLENASQSNESDDTSTDQSPVPPAPLKETSFSIGLQVLIPFLLAGFGTVAAGMVLDIVQHWTVFTEVTEVFILVPALLGLKGNLEMTLASRLSTAANIGQMDTAKDMWKMIMGNLALIQVQATVVGFLASIAAVIFGWIPEGNFRMGHAILLCASSVATAFIASLALGLIMIGVIIASRKVGINPDNVATPIAASLGDLITLSLLAGISTGLYKELEFNNYANPMVCAFFVALTPIWVLIARRIPSTREVLYSGWEPVIIAMAISSVGGLILDKTVSNPNFAGMAVFTPVINGVGGNLVAVQASRISTYLHMNALPIVEPNPAPRKCPTPWGTFFGSGVNSRSAKVLFLLVAPGHLVFLYTINSMRGGHTTLTYIFIAFYLAAALLQVIILLYLADWMVNWMWRRGMDPDNFSIPYLTALGDLLGTGFLALCFHILWLIGDRDTDVGD", "length": 544 }, "evidence": [ { "id": "A0A5G2QSK8", "url": "https://omabrowser.org/oma/group/A0A5G2QSK8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BJA2-1", "protein_name": "Solute carrier family 41 member 1", "gene_name": "Slc41a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSKPEPKDIHQPNGTGPTPSPCSSDGPGREPLAGTSEFLGPDGVEVVVIESRANAKGIREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGQMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELKHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEPTPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD", "length": 512 }, "evidence": [ { "id": "A0A5G2QSK8", "url": "https://omabrowser.org/oma/group/A0A5G2QSK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IVJ1-1", "protein_name": "Solute carrier family 41 member 1", "gene_name": "SLC41A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSKPEPKDVHQLNGTGPSASPCSSDGPGREPLAGTSEFLGPDGAGVEVVIESRANAKGVREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELNHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEQAPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD", "length": 513 }, "evidence": [ { "id": "A0A5G2QSK8", "url": "https://omabrowser.org/oma/group/A0A5G2QSK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "magnesium:sodium antiporter activity", "id": "GO:0061768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061768", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8" } ], "pmid": "" }, { "name": "monoatomic cation transmembrane transporter activity", "id": "GO:0008324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008324", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cellular response to magnesium ion", "id": "GO:0071286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071286", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8" } ], "pmid": "" }, { "name": "intracellular magnesium ion homeostasis", "id": "GO:0010961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010961", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8" } ], "pmid": "" }, { "name": "magnesium ion transport", "id": "GO:0015693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015693", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSK8" }, { "id": "PF01769", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01769" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SLC41A/MgtE integral membrane", "eco_id": "ECO_0000259", "start_pos": 140, "end_pos": 274, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 19 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 477, "end_pos": 479 }, { "start_pos": 70, "end_pos": 72 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSN2-1", "uniprot_ac": "A0A5G2QSN2", "uniprot_id": "A0A5G2QSN2_PIG", "mass": { "chemical_mass": 34746.0, "monoisotopic_mass": 34746.0 }, "refseq": { "ac": "XP_005652899", "name": "olfactory receptor 7G1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652899" }, "gene_names": [ { "name": "LOC100737876", "type": "recommended", "evidence": [ { "id": "A0A5G2QSN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2" } ] }, { "name": "LOC100737876", "type": "synonym", "evidence": [ { "id": "XP_005652899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652899" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QSN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7G1-like", "type": "synonym", "evidence": [ { "id": "XP_005652899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652899" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100737876", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2", "locus": {} } ], "crossref": [ { "id": "A0A5G2QSN2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737876", "url": "https://www.ncbi.nlm.nih.gov/gene/100737876", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737876", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737876", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTEIRIP", "url": "https://omabrowser.org/oma/group/CTEIRIP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QSN2", "url": "https://www.orthodb.org/?gene=A0A5G2QSN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005652899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652899", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QSN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRNQTEVSEFLLMRLTEDPELKIILFCLFLSVYLVTILGNLFIVLAVISDSHLHTPMYLFLSNLSFTDICLSTTTIPKILVNIQAQNQSISYAGCITQISFALTSACWENFLLGAMAYDRYVAICHPLRYPVIMNPHFCVLLILLSLFISAIVALLHSLMVLQLSFCTDLEIPLFFCEVVQVIKLACSDALINNILLYFAVSILGVIPLSGIIFSYTQIVSSILRKLSVGKRYKAFSTCGSHLSAVSLFYGTGFGVYICSAIPQSSRKTAVASLMYSMVTPMLNPFIYSLRNRDMKGALKKLMGGVPYFL", "length": 312, "header": "tr|A0A5G2QSN2-1|A0A5G2QSN2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100737876 PE=3 SV=1 CANONICAL=A0A5G2QSN2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2/entry#A0A5G2QSN2-1", "sequence": { "sequence": "MEPRNQTEVSEFLLMRLTEDPELKIILFCLFLSVYLVTILGNLFIVLAVISDSHLHTPMYLFLSNLSFTDICLSTTTIPKILVNIQAQNQSISYAGCITQISFALTSACWENFLLGAMAYDRYVAICHPLRYPVIMNPHFCVLLILLSLFISAIVALLHSLMVLQLSFCTDLEIPLFFCEVVQVIKLACSDALINNILLYFAVSILGVIPLSGIIFSYTQIVSSILRKLSVGKRYKAFSTCGSHLSAVSLFYGTGFGVYICSAIPQSSRKTAVASLMYSMVTPMLNPFIYSLRNRDMKGALKKLMGGVPYFL", "length": 312, "header": "tr|A0A5G2QSN2-1|A0A5G2QSN2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100737876 PE=3 SV=1 CANONICAL=A0A5G2QSN2-1" }, "locus": { "chromosome": "2", "start_pos": 67243256, "end_pos": 67242321, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072086.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072086.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061178.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061178.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737876", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737876", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSN2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSN2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSN2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSN2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSS1-1", "uniprot_ac": "A0A5G2QSS1", "uniprot_id": "A0A5G2QSS1_PIG", "mass": { "chemical_mass": 41199.0, "monoisotopic_mass": 41199.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100157349", "type": "recommended", "evidence": [ { "id": "A0A5G2QSS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QSS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" }, { "database": "UniProtKB", "id": "A0A5G2QWM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWM3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100157349", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1", "locus": {} } ], "crossref": [ { "id": "A0A5G2QSS1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15232", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15232", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157349", "url": "https://www.ncbi.nlm.nih.gov/gene/100157349", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157349", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157349", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TSRNHFT", "url": "https://omabrowser.org/oma/group/TSRNHFT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QWM3", "url": "https://www.orthodb.org/?gene=A0A5G2QWM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QSS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVTGSAHLQQRASRCVDPVGHAPHQELPTPHTLSAPPHRPMPPWAGLAVSQRLQGLTPQRTANNGTAVEEFVLQSFSEEPGPRILFLAMFLLLYLGALAGNALIVTAISLHPGLHTPMYFFLTNLAILDIVCTSTVVPKLLENLALKGGTITYQGCMTQLFFLTWCLGAELLLLTVMAYDRYVAICRPLHYSRLMGRPVCALLAGSVWAASVVSTSVHTGLMTRLTFCSHNQIQHFLCEIPTLLLLSCSPTTLNNVMMVLADVYFGVVNFLLTLASYAYIIASIVRMRSATGRQRAFSTCSSHLLVVTLYYSTVIYTYILPGSGSSLENGKVVAVLYTAVSPTLNPLIYSLRNKDVKVALGKVFSCIRGRHGPCRLTG", "length": 378, "header": "tr|A0A5G2QSS1-1|A0A5G2QSS1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100157349 PE=3 SV=1 CANONICAL=A0A5G2QSS1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1/entry#A0A5G2QSS1-1", "sequence": { "sequence": "MVTGSAHLQQRASRCVDPVGHAPHQELPTPHTLSAPPHRPMPPWAGLAVSQRLQGLTPQRTANNGTAVEEFVLQSFSEEPGPRILFLAMFLLLYLGALAGNALIVTAISLHPGLHTPMYFFLTNLAILDIVCTSTVVPKLLENLALKGGTITYQGCMTQLFFLTWCLGAELLLLTVMAYDRYVAICRPLHYSRLMGRPVCALLAGSVWAASVVSTSVHTGLMTRLTFCSHNQIQHFLCEIPTLLLLSCSPTTLNNVMMVLADVYFGVVNFLLTLASYAYIIASIVRMRSATGRQRAFSTCSSHLLVVTLYYSTVIYTYILPGSGSSLENGKVVAVLYTAVSPTLNPLIYSLRNKDVKVALGKVFSCIRGRHGPCRLTG", "length": 378, "header": "tr|A0A5G2QSS1-1|A0A5G2QSS1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100157349 PE=3 SV=1 CANONICAL=A0A5G2QSS1-1" }, "locus": { "chromosome": "14", "start_pos": 141586446, "end_pos": 141585127, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071568.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071568.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067181.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067181.1" } ] } }, { "isoform_ac": "A0A5G2QWM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1/entry#A0A5G2QWM3-1", "sequence": { "sequence": "MPPWAGLAVSQRLQGLTPQRTANNGTAVEEFVLQSFSEEPGPRILFLAMFLLLYLGALAGNALIVTAISLHPGLHTPMYFFLTNLAILDIVCTSTVVPKLLENLALKGGTITYQGCMTQLFFLTWCLGAELLLLTVMAYDRYVAICRPLHYSRLMGRPVCALLAGSVWAASVVSTSVHTGLMTRLTFCSHNQIQHFLCEIPTLLLLSCSPTTLNNVMMVLADVYFGVVNFLLTLASYAYIIASIVRMRSATGRQRAFSTCSSHLLVVTLYYSTVIYTYILPGSGSSLENGKVVAVLYTAVSPTLNPLIYSLRNKDVKVALGKVFSCIRGRHGPCRLTG", "length": 338, "header": "tr|A0A5G2QWM3-1|A0A5G2QWM3_PIG Computationally mapped isoform of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100157349 PE=3 SV=1 CANONICAL=A0A5G2QSS1-1" }, "locus": { "chromosome": "14", "start_pos": 141586140, "end_pos": 141585127, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080637.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080637.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069349.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069349.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157349", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157349", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSS1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 378, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSS1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSS1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSS1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 349, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSX0-1", "uniprot_ac": "A0A5G2QSX0", "uniprot_id": "A0A5G2QSX0_PIG", "mass": { "chemical_mass": 28971.0, "monoisotopic_mass": 28971.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QSX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSX0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSX0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSX0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSX0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSX0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSX0", "locus": {} } ], "crossref": [ { "id": "A0A5G2QSX0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QSX0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNTSARNPAKIDSEKQAKMIMAGNFLIVVTVTFDSHLHSIPMYFLLGNLSFLDMSISTITTPKMVADFLKENKTISLWGCMAQMFFLHFLGGSEMTLLIVMAVDRYIAICRPLHYTTIMNHRMLMGSVLLSWAVGFVHTMSQMVFTITLPFCGPNVVDNIFCDLPLVLKLACTDTYVLELLVIADSGLLSFICFILLLISYTALSTLSFSVDKFLSVFYSVITPLLNPIIYTLRNQEMKAAMSRLRTQHVSSRQNF", "length": 257, "header": "tr|A0A5G2QSX0-1|A0A5G2QSX0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2QSX0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSX0/entry#A0A5G2QSX0-1", "sequence": { "sequence": "MKNTSARNPAKIDSEKQAKMIMAGNFLIVVTVTFDSHLHSIPMYFLLGNLSFLDMSISTITTPKMVADFLKENKTISLWGCMAQMFFLHFLGGSEMTLLIVMAVDRYIAICRPLHYTTIMNHRMLMGSVLLSWAVGFVHTMSQMVFTITLPFCGPNVVDNIFCDLPLVLKLACTDTYVLELLVIADSGLLSFICFILLLISYTALSTLSFSVDKFLSVFYSVITPLLNPIIYTLRNQEMKAAMSRLRTQHVSSRQNF", "length": 257, "header": "tr|A0A5G2QSX0-1|A0A5G2QSX0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2QSX0-1" }, "locus": { "chromosome": "AEMK02000336.1", "start_pos": 114388, "end_pos": 112474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085756.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085756.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067236.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067236.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSX0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSX0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSX0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSX0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSX0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSX0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSX0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSX0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 257, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSX0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSX0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSX0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 205, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 49, "end_pos": 51 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSY0-1", "uniprot_ac": "A0A5G2QSY0", "uniprot_id": "A0A5G2QSY0_PIG", "mass": { "chemical_mass": 35287.0, "monoisotopic_mass": 35287.0 }, "refseq": { "ac": "XP_020937915", "name": "olfactory receptor 1J4-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937915" }, "gene_names": [ { "name": "LOC100155678", "type": "recommended", "evidence": [ { "id": "A0A5G2QSY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0" } ] }, { "name": "LOC100155678", "type": "synonym", "evidence": [ { "id": "XP_020937915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937915" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QSY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1J4-like", "type": "synonym", "evidence": [ { "id": "XP_020937915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937915" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100155678", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0", "locus": {} } ], "crossref": [ { "id": "A0A5G2QSY0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000046206", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000046206", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155678", "url": "https://www.ncbi.nlm.nih.gov/gene/100155678", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155678", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155678", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PVWAKQQ", "url": "https://omabrowser.org/oma/group/PVWAKQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QSY0", "url": "https://www.orthodb.org/?gene=A0A5G2QSY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020937915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937915", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QSY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTENQSSMSEFLLQGFPVWAKQQDILFALFLCMYLTTLLGNLLIILLIRLDPHLHTPMYFFLSQLALTDVSFSSVTVPKMLMDIQTQDQSIPYAGCVTQTYFFIFFACIDNFLLVVMAYDRYVAICHPLHYTIIMREELCLCLLTGSWLFSCAYALTHTLLLARLSFCDDNIIPHFFCDLAALLKLSCSDTSLNELVIFTLGSAVFIFPLSGILISYGRIGVSILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYLSSSSSQSQDKSIIASVMYTVVTPMLNPFIYSLRNRDMTLALRILFRNINLFVK", "length": 313, "header": "tr|A0A5G2QSY0-1|A0A5G2QSY0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100155678 PE=3 SV=1 CANONICAL=A0A5G2QSY0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0/entry#A0A5G2QSY0-1", "sequence": { "sequence": "MRTENQSSMSEFLLQGFPVWAKQQDILFALFLCMYLTTLLGNLLIILLIRLDPHLHTPMYFFLSQLALTDVSFSSVTVPKMLMDIQTQDQSIPYAGCVTQTYFFIFFACIDNFLLVVMAYDRYVAICHPLHYTIIMREELCLCLLTGSWLFSCAYALTHTLLLARLSFCDDNIIPHFFCDLAALLKLSCSDTSLNELVIFTLGSAVFIFPLSGILISYGRIGVSILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYLSSSSSQSQDKSIIASVMYTVVTPMLNPFIYSLRNRDMTLALRILFRNINLFVK", "length": 313, "header": "tr|A0A5G2QSY0-1|A0A5G2QSY0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100155678 PE=3 SV=1 CANONICAL=A0A5G2QSY0-1" }, "locus": { "chromosome": "AEMK02000598.1", "start_pos": 816908, "end_pos": 815970, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084523.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084523.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061274.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061274.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155678", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155678", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSY0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSY0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSY0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSY0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QSZ7-1", "uniprot_ac": "A0A5G2QSZ7", "uniprot_id": "A0A5G2QSZ7_PIG", "mass": { "chemical_mass": 44775.0, "monoisotopic_mass": 44775.0 }, "refseq": { "ac": "XP_020936538", "name": "heat shock transcription factor, Y-linked-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936538" }, "gene_names": [ { "name": "LOC110257872", "type": "synonym", "evidence": [ { "id": "XP_020936538", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936538" } ] } ], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QSZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSZ7/entry#names_and_taxonomy" } ] }, { "name": "heat shock transcription factor, Y-linked-like", "type": "synonym", "evidence": [ { "id": "XP_020936538", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936538" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSZ7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSZ7", "locus": {} } ], "crossref": [ { "id": "A0A5G2QSZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000051247", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000051247", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110257872", "url": "https://www.ncbi.nlm.nih.gov/gene/110257872", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110257872", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257872", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVINEEC", "url": "https://omabrowser.org/oma/group/IVINEEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QSZ7", "url": "https://www.orthodb.org/?gene=A0A5G2QSZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020936538", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936538", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QSZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEECFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2QSZ7-1|A0A5G2QSZ7_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QSZ7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSZ7/entry#A0A5G2QSZ7-1", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEECFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2QSZ7-1|A0A5G2QSZ7_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QSZ7-1" }, "locus": { "chromosome": "Y", "start_pos": 23677057, "end_pos": 23675429, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088908.1", "url": "https://www.ensembl.org/id/ENSSSCT00000088908.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067957.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067957.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 356, "start_aa": "Thr", "end_pos": 356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr356", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "ssc:110257872", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257872", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSZ7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSZ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QSZ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QSZ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QSZ7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QSZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSZ7" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 356 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2QT00-1", "uniprot_ac": "A0A5G2QT00", "uniprot_id": "A0A5G2QT00_PIG", "mass": { "chemical_mass": 23373.0, "monoisotopic_mass": 23373.0 }, "refseq": { "ac": "XP_020928091", "name": "Sin3A associated protein 30", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928091" }, "gene_names": [ { "name": "SAP30", "type": "recommended", "evidence": [ { "id": "A0A5G2QT00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" } ] }, { "name": "SAP30", "type": "synonym", "evidence": [ { "id": "XP_020928091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928091" } ] } ], "protein_names": [ { "name": "Sin3A associated protein 30", "type": "synonym", "evidence": [ { "id": "XP_020928091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928091" }, { "id": "A0A5G2QT00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT00", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SAP30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00", "locus": { "chromosome": "14", "start_pos": 16673318, "end_pos": 16681928, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000030118", "url": "https://www.ensembl.org/id/ENSSSCG00000030118" } ] } } ], "crossref": [ { "id": "ENSSSCG00000030118", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000030118", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100620430", "url": "https://www.ncbi.nlm.nih.gov/gene/100620430", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DEYRICC", "url": "https://omabrowser.org/oma/group/DEYRICC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13286", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13286", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13286:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13286:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13866", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13866", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13867", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13867", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3214815", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214815", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020928091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928091", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QT00", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QT00-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGFTPEDISRGGDAAAAVAAVVAAAAAAAASAGNGAGAGSGAEVPGAGAVSVAGPPGAAGPGPGQLCCLREDGERCSRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYFIYSVKNDKNKSDLKVDSGVH", "length": 221, "header": "tr|A0A5G2QT00-1|A0A5G2QT00_PIG Isoform 1 of Sin3A associated protein 30 OS=Sus scrofa OX=9823 GN=SAP30 PE=1 SV=1 CANONICAL=A0A5G2QT00-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QT00-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00/entry#A0A5G2QT00-1", "sequence": { "sequence": "MNGFTPEDISRGGDAAAAVAAVVAAAAAAAASAGNGAGAGSGAEVPGAGAVSVAGPPGAAGPGPGQLCCLREDGERCSRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYFIYSVKNDKNKSDLKVDSGVH", "length": 221, "header": "tr|A0A5G2QT00-1|A0A5G2QT00_PIG Isoform 1 of Sin3A associated protein 30 OS=Sus scrofa OX=9823 GN=SAP30 PE=1 SV=1 CANONICAL=A0A5G2QT00-1" }, "locus": { "chromosome": "14", "start_pos": 16681623, "end_pos": 16676184, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081064.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081064.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067271.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067271.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT00", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3214815", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214815", "resource": "Reactome", "description": "HDACs deacetylate histones" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZC08-1", "protein_name": "Sin3A associated protein 30", "gene_name": "Sap30", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGFTPEEMSRGGDAAAAVAAVVAAAAAAASAGNGNAAGGGAEVPGAGAVSASGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFKSIPVNEKDTLTCFIYSVRNDKNKSDLKADSGVH", "length": 220 }, "evidence": [ { "id": "A0A5G2QT00", "url": "https://omabrowser.org/oma/group/A0A5G2QT00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B806-1", "protein_name": "Sin3A associated protein 30", "gene_name": "SAP30", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNGFTPEDMSRGGDAAAAVAAVVAAAAAAASAGNGAGAGAGAEVPGAGAVSAAGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYFIYSVKNDKNKSDLKVDSSVH", "length": 220 }, "evidence": [ { "id": "A0A5G2QT00", "url": "https://omabrowser.org/oma/group/A0A5G2QT00/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HKY1-1", "protein_name": "Histone deacetylase complex subunit SAP30", "gene_name": "Sap30", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNGFTPEEMSRSGDAAAAVAAVVAAAAAAASAGNGNAAGGGAEVPGAGAVSAAGPPGAAGPGLGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYFIYSVKNDKNKSDLKVDSGVH", "length": 220 }, "evidence": [ { "id": "A0A5G2QT00", "url": "https://omabrowser.org/oma/group/A0A5G2QT00/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O75446-1", "protein_name": "Histone deacetylase complex subunit SAP30", "gene_name": "SAP30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGFTPDEMSRGGDAAAAVAAVVAAAAAAASAGNGTGAGTGAEVPGAGAVSAAGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYFIYSVKNDKNKSDLKVDSGVH", "length": 220 }, "evidence": [ { "id": "A0A5G2QT00", "url": "https://omabrowser.org/oma/group/A0A5G2QT00/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88574-1", "protein_name": "Histone deacetylase complex subunit SAP30", "gene_name": "Sap30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGFTPEEMSRGGDAAAAVAAVVAAAAAAASAGNGNAAGGGAEVPGAGAVSASGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFKSIPVNEKDTLTCFIYSVRNDKNKSDLKADSGVH", "length": 220 }, "evidence": [ { "id": "A0A5G2QT00", "url": "https://omabrowser.org/oma/group/A0A5G2QT00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT00", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT00", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT00", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT00", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT00", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT00", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT00", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT00", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QT00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" }, { "id": "PF13867", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13867" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histone deacetylase complex subunit SAP30 Sin3 binding", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 206, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QT00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT00" }, { "id": "PF13866", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13866" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histone deacetylase complex subunit SAP30 zinc-finger", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 134, "start_aa": "Gly", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QT11-1", "uniprot_ac": "A0A5G2QT11", "uniprot_id": "A0A5G2QT11_PIG", "mass": { "chemical_mass": 36111.0, "monoisotopic_mass": 36111.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110260680", "type": "recommended", "evidence": [ { "id": "A0A5G2QT11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QT11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110260680", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11", "locus": {} } ], "crossref": [ { "id": "A0A5G2QT11", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QT11", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QT11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QT11-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNHTIKTFILLGLTDDPRIKVLIFIFLFFTYMLSAAGNLTIISLTFIDCRLRTAMYFFLQNFSFLEISFTTACIPRFLYNIATGDKIITYAACAAQIFFTYLFGIMEFFLLATMSFDRYVAICKPLHYVTIMNNRVCNRLIISCWMAGLCIIIPPLSLGLNLEFCDSNVIDHFFCDATPLLKISCSDTQFIERMILVCAVLTFIMTLVCVVLSYIYIIMTVLRFSSSQQRKKAFSTCSSHMIVVSITYGSCIFIYIKPSAKKEVALNKGVSLLISSISPTLNPFIYTLRNKQVKKALNDLIKRITFFFKKKGTIK", "length": 316, "header": "tr|A0A5G2QT11-1|A0A5G2QT11_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110260680 PE=3 SV=2 CANONICAL=A0A5G2QT11-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QT11-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11/entry#A0A5G2QT11-1", "sequence": { "sequence": "MRNHTIKTFILLGLTDDPRIKVLIFIFLFFTYMLSAAGNLTIISLTFIDCRLRTAMYFFLQNFSFLEISFTTACIPRFLYNIATGDKIITYAACAAQIFFTYLFGIMEFFLLATMSFDRYVAICKPLHYVTIMNNRVCNRLIISCWMAGLCIIIPPLSLGLNLEFCDSNVIDHFFCDATPLLKISCSDTQFIERMILVCAVLTFIMTLVCVVLSYIYIIMTVLRFSSSQQRKKAFSTCSSHMIVVSITYGSCIFIYIKPSAKKEVALNKGVSLLISSISPTLNPFIYTLRNKQVKKALNDLIKRITFFFKKKGTIK", "length": 316, "header": "tr|A0A5G2QT11-1|A0A5G2QT11_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110260680 PE=3 SV=2 CANONICAL=A0A5G2QT11-1" }, "locus": { "chromosome": "5", "start_pos": 20778445, "end_pos": 20776892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081007.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081007.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065127.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065127.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QT11-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 316, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QT11-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QT11" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QT11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT11" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 39, "end_pos": 41 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QT77-1", "uniprot_ac": "A0A5G2QT77", "uniprot_id": "A0A5G2QT77_PIG", "mass": { "chemical_mass": 35452.0, "monoisotopic_mass": 35452.0 }, "refseq": { "ac": "XP_003355495", "name": "olfactory receptor 6C2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355495" }, "gene_names": [ { "name": "LOC100524864", "type": "recommended", "evidence": [ { "id": "A0A5G2QT77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77" } ] }, { "name": "LOC100524864", "type": "synonym", "evidence": [ { "id": "XP_003355495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355495" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QT77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6C2-like", "type": "synonym", "evidence": [ { "id": "XP_003355495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355495" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT77", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT77", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100524864", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77", "locus": {} } ], "crossref": [ { "id": "A0A5G2QT77", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QT77", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524864", "url": "https://www.ncbi.nlm.nih.gov/gene/100524864", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524864", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524864", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ssc:100736675", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736675", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MENHTIT", "url": "https://omabrowser.org/oma/group/MENHTIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QT77", "url": "https://www.orthodb.org/?gene=A0A5G2QT77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF50", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF50", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003355495", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355495", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QT77", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QT77-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNHTITTFILLGLTDNPQLQIPIFMFLFLTYMLSITGNLTIISLTLVGSHLKTPMYYFLQNFALLEISFTTACIPRYLYNITTGDRSITYNICVIQVFFTDVFGVTEFFLLAAMSYDRYVAICKPLHYMSIMNSRVCRRLVLCCWISGLLIILPPLTLFLDLKFCDSNVIDYFFCDASPILKISCSDTWLIEQLVIVCAVLTFILTLVCVVLSYLYILKTILRFPSAQQRKRAFSTCSSHMIVVSITYGSCIFIYIKPSAKESVAINKAVTLLMTSIAPMLNPFIYTLRNKQVRRALSDSFKKLALIAKK", "length": 311, "header": "tr|A0A5G2QT77-1|A0A5G2QT77_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524864 PE=3 SV=1 CANONICAL=A0A5G2QT77-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QT77-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77/entry#A0A5G2QT77-1", "sequence": { "sequence": "MKNHTITTFILLGLTDNPQLQIPIFMFLFLTYMLSITGNLTIISLTLVGSHLKTPMYYFLQNFALLEISFTTACIPRYLYNITTGDRSITYNICVIQVFFTDVFGVTEFFLLAAMSYDRYVAICKPLHYMSIMNSRVCRRLVLCCWISGLLIILPPLTLFLDLKFCDSNVIDYFFCDASPILKISCSDTWLIEQLVIVCAVLTFILTLVCVVLSYLYILKTILRFPSAQQRKRAFSTCSSHMIVVSITYGSCIFIYIKPSAKESVAINKAVTLLMTSIAPMLNPFIYTLRNKQVRRALSDSFKKLALIAKK", "length": 311, "header": "tr|A0A5G2QT77-1|A0A5G2QT77_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524864 PE=3 SV=1 CANONICAL=A0A5G2QT77-1" }, "locus": { "chromosome": "5", "start_pos": 20832802, "end_pos": 20831870, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076617.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076617.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068038.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068038.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT77", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524864", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524864", "resource": "KEGG Pathway" }, { "id": "ssc:100736675", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736675", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3N3Y0-1", "protein_name": "Olfactory receptor", "gene_name": "OR6C202", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MENHTITTFILVGLTDDPQLQIPIFMFLFLTYMFSITGNLTIIFLTLMDPHLKTPMYYFLQNFALLEVSFTTACIPRYLYNIATGDRSITYAICIIQVFFTDVFGVTEFFLLAIMSYDRYVAICKPLHYMTIMNSRVCQRLVLCCWISGLLIILPPLILFLNLKFCDSNIIDYFFCDASPILKISCSDTWLIEQLVIVSAVLTFILTLVCVALSYIYIIKTIVRLPSSQQRKRAFSTCSSHMIVVSITYGSCIFVYVKPSAKESVAINKGVAVLMTSIAPMLNPFIYTLRNKQVRQAFSDSFKKLVLVSKKQKTAQA", "length": 317 }, "evidence": [ { "id": "A0A5G2QT77", "url": "https://omabrowser.org/oma/group/A0A5G2QT77/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VFH6-1", "protein_name": "Olfactory receptor", "gene_name": "Or6c202", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNNTITTFILLGLTDDPQLQIPIFVFLFFAYMLSITGNLTIISLTILDSHLKTPMYFFLQNFSILEISFTSACIPRYLYNIATGDRSITYNVCVIQVFFTDVFGVIEFFLLAIMSYDRYVAICKPLHYVTIMSSKVCQTLVLCCWSAGLLIILPPLTLFLNLRFCDSNVIDYFFCDASPILKISCSDTWLIEQLVIVCAVLTFILTLVCVTLSYVHIIKTILRFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKESVAINKGVAVLMTSIAPMLNPFIYTLRNKQVRQAFSDSFKKIAIISMKKENVQI", "length": 317 }, "evidence": [ { "id": "A0A5G2QT77", "url": "https://omabrowser.org/oma/group/A0A5G2QT77/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT77", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT77", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT77", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QT77-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QT77-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QT77" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QT77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT77" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 39, "end_pos": 41 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QT90-1", "uniprot_ac": "A0A5G2QT90", "uniprot_id": "A0A5G2QT90_PIG", "mass": { "chemical_mass": 34637.0, "monoisotopic_mass": 34637.0 }, "refseq": { "ac": "XP_003480842", "name": "olfactory receptor 7D2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480842" }, "gene_names": [ { "name": "LOC100521247", "type": "recommended", "evidence": [ { "id": "A0A5G2QT90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90" } ] }, { "name": "LOC100521247", "type": "synonym", "evidence": [ { "id": "XP_003480842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480842" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QT90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7D2-like", "type": "synonym", "evidence": [ { "id": "XP_003480842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480842" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100521247", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90", "locus": {} } ], "crossref": [ { "id": "A0A5G2QT90", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QT90", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521247", "url": "https://www.ncbi.nlm.nih.gov/gene/100521247", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521247", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521247", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VFTCMDN", "url": "https://omabrowser.org/oma/group/VFTCMDN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QT90", "url": "https://www.orthodb.org/?gene=A0A5G2QT90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003480842", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480842", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QT90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QT90-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAGNQTRVLEFLLLGLSEDPELQPLLFGLFLSMYLVSMLGNLLIILAVSSDSRLHTPMYFFLSHLSFSDICYSSTIVPKMLVNIQTANKAIMYAGCITQMHFSIVFLCLDNLLLTVMAYDRFVAICHPLHYMIMMNPLLCGLLALVSWSVSILAPLIHSLMVLHLSFCSHTEIPHFFCELSEVLETSCSDALSNYIALYSLTGLLGIIPLTGILYSYSKILSSILKMSSAEGKYKVFSTCGSHLMVISLFYGTGLSVYLSSAFSASSSKGTVTSVMYTVVIPMLNPFIYSLRNRDLQGALRKCVSRSFYPF", "length": 312, "header": "tr|A0A5G2QT90-1|A0A5G2QT90_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100521247 PE=3 SV=1 CANONICAL=A0A5G2QT90-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QT90-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90/entry#A0A5G2QT90-1", "sequence": { "sequence": "MDAGNQTRVLEFLLLGLSEDPELQPLLFGLFLSMYLVSMLGNLLIILAVSSDSRLHTPMYFFLSHLSFSDICYSSTIVPKMLVNIQTANKAIMYAGCITQMHFSIVFLCLDNLLLTVMAYDRFVAICHPLHYMIMMNPLLCGLLALVSWSVSILAPLIHSLMVLHLSFCSHTEIPHFFCELSEVLETSCSDALSNYIALYSLTGLLGIIPLTGILYSYSKILSSILKMSSAEGKYKVFSTCGSHLMVISLFYGTGLSVYLSSAFSASSSKGTVTSVMYTVVIPMLNPFIYSLRNRDLQGALRKCVSRSFYPF", "length": 312, "header": "tr|A0A5G2QT90-1|A0A5G2QT90_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100521247 PE=3 SV=1 CANONICAL=A0A5G2QT90-1" }, "locus": { "chromosome": "2", "start_pos": 68140257, "end_pos": 68139322, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091194.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091194.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061380.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061380.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521247", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521247", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QT90-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QT90-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QT90" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QT90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT90" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QT93-1", "uniprot_ac": "A0A5G2QT93", "uniprot_id": "A0A5G2QT93_PIG", "mass": { "chemical_mass": 35680.0, "monoisotopic_mass": 35680.0 }, "refseq": { "ac": "XP_005657182", "name": "olfactory receptor 5H8-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657182" }, "gene_names": [ { "name": "LOC100623013", "type": "recommended", "evidence": [ { "id": "A0A5G2QT93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93" } ] }, { "name": "LOC100623013", "type": "synonym", "evidence": [ { "id": "XP_005657182", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657182" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QT93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5H8-like", "type": "synonym", "evidence": [ { "id": "XP_005657182", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657182" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100623013", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93", "locus": {} } ], "crossref": [ { "id": "A0A5G2QT93", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QT93", "database": "AlphaFoldDB", "categories": [] }, { "id": "100623013", "url": "https://www.ncbi.nlm.nih.gov/gene/100623013", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623013", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623013", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QT93", "url": "https://www.orthodb.org/?gene=A0A5G2QT93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005657182", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657182", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QT93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QT93-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METKNATELTEFVLTGLKYQSEWQIPLFLLFLIIYLITLLGNLGLIALICNDPHLHIPMYLFLGNLAFVDTWLSSTVTPNMLVNFFAKSKMISFSECVVQFFSFTLCVTTECFLLATMAYDRYVAICKPLLYPVIMTNRLCMWLLVLSFLGDLFHATLHNYFLFRLTFCDSIILHHFYCDIMPLLKISCTDPSINYLMVFIFPGIIQVFTIYVVLVSYTLILFTILKRRSLQGINKAFSTCGAHLLSVSLYYGPLLFMYVLPGSAQENDRDMMDSLFYTVIIPFLNPVIYSLRNKKVRDSLTKMLKRNV", "length": 309, "header": "tr|A0A5G2QT93-1|A0A5G2QT93_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100623013 PE=3 SV=1 CANONICAL=A0A5G2QT93-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QT93-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93/entry#A0A5G2QT93-1", "sequence": { "sequence": "METKNATELTEFVLTGLKYQSEWQIPLFLLFLIIYLITLLGNLGLIALICNDPHLHIPMYLFLGNLAFVDTWLSSTVTPNMLVNFFAKSKMISFSECVVQFFSFTLCVTTECFLLATMAYDRYVAICKPLLYPVIMTNRLCMWLLVLSFLGDLFHATLHNYFLFRLTFCDSIILHHFYCDIMPLLKISCTDPSINYLMVFIFPGIIQVFTIYVVLVSYTLILFTILKRRSLQGINKAFSTCGAHLLSVSLYYGPLLFMYVLPGSAQENDRDMMDSLFYTVIIPFLNPVIYSLRNKKVRDSLTKMLKRNV", "length": 309, "header": "tr|A0A5G2QT93-1|A0A5G2QT93_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100623013 PE=3 SV=1 CANONICAL=A0A5G2QT93-1" }, "locus": { "chromosome": "13", "start_pos": 161324862, "end_pos": 161323936, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090168.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090168.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067366.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067366.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623013", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623013", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT93", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QT93-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QT93-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QT93" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QT93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT93" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QTB3-1", "uniprot_ac": "A0A5G2QTB3", "uniprot_id": "A0A5G2QTB3_PIG", "mass": { "chemical_mass": 34793.0, "monoisotopic_mass": 34793.0 }, "refseq": { "ac": "XP_020940780", "name": "olfactory receptor 7G1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940780" }, "gene_names": [ { "name": "LOC110259633", "type": "recommended", "evidence": [ { "id": "A0A5G2QTB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3" } ] }, { "name": "LOC110259633", "type": "synonym", "evidence": [ { "id": "XP_020940780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940780" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QTB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7G1-like", "type": "synonym", "evidence": [ { "id": "XP_020940780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940780" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTB3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTB3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259633", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3", "locus": {} } ], "crossref": [ { "id": "A0A5G2QTB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110259633", "url": "https://www.ncbi.nlm.nih.gov/gene/110259633", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110259633", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259633", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QTB3", "url": "https://www.orthodb.org/?gene=A0A5G2QTB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020940780", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940780", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QTB3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPRNKTGVSQFLLMEVTEDPELQLFLFILFLSIYLVTILGNLLIILTVLSDSHLHTPMYFFLYNLSFTDICLSTTTITKMLVNIHTQNQSIPYAGCLTQIYFVLVFASLESCLLAAMAYDRYVAICHPLRYTVIMNSHICGQLILFSLFISILDALLHSLMVLQLTFCTDLQIPLFFCEVVQVIKLACSDALINNILIYVATSVFGGIPVCGIIFSYVQIVSSVLRMPSVGGKYKAFSTCGSHLSVVSLFYGTGLGVYISSALTNSSRKTAVVSMMYTVVPQMMNPFIYSLRNRDMKGALRKLSSKIPLFF", "length": 312, "header": "tr|A0A5G2QTB3-1|A0A5G2QTB3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259633 PE=3 SV=1 CANONICAL=A0A5G2QTB3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QTB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3/entry#A0A5G2QTB3-1", "sequence": { "sequence": "MGPRNKTGVSQFLLMEVTEDPELQLFLFILFLSIYLVTILGNLLIILTVLSDSHLHTPMYFFLYNLSFTDICLSTTTITKMLVNIHTQNQSIPYAGCLTQIYFVLVFASLESCLLAAMAYDRYVAICHPLRYTVIMNSHICGQLILFSLFISILDALLHSLMVLQLTFCTDLQIPLFFCEVVQVIKLACSDALINNILIYVATSVFGGIPVCGIIFSYVQIVSSVLRMPSVGGKYKAFSTCGSHLSVVSLFYGTGLGVYISSALTNSSRKTAVVSMMYTVVPQMMNPFIYSLRNRDMKGALRKLSSKIPLFF", "length": 312, "header": "tr|A0A5G2QTB3-1|A0A5G2QTB3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259633 PE=3 SV=1 CANONICAL=A0A5G2QTB3-1" }, "locus": { "chromosome": "2", "start_pos": 67218177, "end_pos": 67217242, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070948.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070948.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068073.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068073.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTB3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110259633", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259633", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTB3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTB3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTB3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTB3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QTB3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QTB3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTB3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QTB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTB3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QTK2-1", "uniprot_ac": "A0A5G2QTK2", "uniprot_id": "A0A5G2QTK2_PIG", "mass": { "chemical_mass": 15108.0, "monoisotopic_mass": 15108.0 }, "refseq": { "ac": "XP_020951270", "name": "zinc finger protein 593", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020951270" }, "gene_names": [ { "name": "ZNF593", "type": "recommended", "evidence": [ { "id": "A0A5G2QTK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2" } ] }, { "name": "ZNF593", "type": "synonym", "evidence": [ { "id": "XP_020951270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020951270" } ] } ], "protein_names": [ { "name": "Zinc finger protein 593", "type": "recommended", "evidence": [ { "id": "A0A5G2QTK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein T86", "type": "synonym", "evidence": [ { "id": "A0A5G2QTK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 593", "type": "synonym", "evidence": [ { "id": "XP_020951270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020951270" } ] } ], "function": [ { "annotation": "Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome. Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2#function" }, { "database": "UniProtKB", "id": "ARBA00056372", "url": "https://www.uniprot.org/uniprotkb/ARBA00056372#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF593", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2", "locus": { "chromosome": "6", "start_pos": 83593278, "end_pos": 83590895, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000045776", "url": "https://www.ensembl.org/id/ENSSSCG00000045776" } ] } } ], "crossref": [ { "id": "A0A5G2QTK2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTK2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045776", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045776", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110261119", "url": "https://www.ncbi.nlm.nih.gov/gene/110261119", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110261119", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261119", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MKDHFRS", "url": "https://omabrowser.org/oma/group/MKDHFRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QTK2", "url": "https://www.orthodb.org/?gene=A0A5G2QTK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46095", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46095", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46095:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46095:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020951270", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020951270", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QTK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRSRRTGAHRAHSLARQMKAKRRRPDLDEIHRELRPQVATRTRPDPGAEPDPDLPGGGLHRCLACARYFIDSANLKTHFRSKDHKKRLKQLSVEPYSQEEAERAAGMGSYVPPQRLAVPTEVSTDVPEMDTST", "length": 134, "header": "tr|A0A5G2QTK2-1|A0A5G2QTK2_PIG Isoform 1 of Zinc finger protein 593 OS=Sus scrofa OX=9823 GN=ZNF593 PE=3 SV=2 CANONICAL=A0A5G2QTK2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QTK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2/entry#A0A5G2QTK2-1", "sequence": { "sequence": "MGRSRRTGAHRAHSLARQMKAKRRRPDLDEIHRELRPQVATRTRPDPGAEPDPDLPGGGLHRCLACARYFIDSANLKTHFRSKDHKKRLKQLSVEPYSQEEAERAAGMGSYVPPQRLAVPTEVSTDVPEMDTST", "length": 134, "header": "tr|A0A5G2QTK2-1|A0A5G2QTK2_PIG Isoform 1 of Zinc finger protein 593 OS=Sus scrofa OX=9823 GN=ZNF593 PE=3 SV=2 CANONICAL=A0A5G2QTK2-1" }, "locus": { "chromosome": "6", "start_pos": 83591700, "end_pos": 83590982, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069657.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069657.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068256.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068256.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110261119", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261119", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7FCM9-1", "protein_name": "Zinc finger protein 593", "gene_name": "znf593", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKSKQVGNHNNGKKKNIAKTWKTKRRTKDLDQIHADMIPTNAAKLLKQDVDYDVTGCGQHYCLHCARYFVDLKTLKEHFKSKPHKKRLKQLREEPYTQAEAERAAGMGSYIPPKTLEVHTQQVEEDMD", "length": 129 }, "evidence": [ { "id": "A0A5G2QTK2", "url": "https://omabrowser.org/oma/group/A0A5G2QTK2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3I3E0-1", "protein_name": "Zinc finger protein 593", "gene_name": "Znf593", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGRSRRTGAHRAHSLARQMKAKKRRPDLDEIHRELRPQGLPRPKPELDAEPDPDLPGGGRHRCLACARYFIDSANLKTHFRSKDHKKRLKQLTIEPYSQEEAERAAGMGSYVPPQRLSVPTEVSTEIPEMDTST", "length": 134 }, "evidence": [ { "id": "A0A5G2QTK2", "url": "https://omabrowser.org/oma/group/A0A5G2QTK2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O00488-1", "protein_name": "Zinc finger protein 593", "gene_name": "ZNF593", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRSRRTGAHRAHSLARQMKAKRRRPDLDEIHRELRPQGSARPQPDPNAEFDPDLPGGGLHRCLACARYFIDSTNLKTHFRSKDHKKRLKQLSVEPYSQEEAERAAGMGSYVPPRRLAVPTEVSTEVPEMDTST", "length": 134 }, "evidence": [ { "id": "A0A5G2QTK2", "url": "https://omabrowser.org/oma/group/A0A5G2QTK2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q553S1-1", "protein_name": "Zinc finger protein 593 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGRYSGHGGTHTKKKQYKRARSTKNRAKDIDQIFDEIQPETIDKFSKFEVDPDLPGMGQNYCIHCSKHFVTNEDLQSHIKGKPHKIRVKELKTKPYSLAESQIPVDNGVKLNRDANGVPTTTDVTGTIKKSTTTTTTTTTV", "length": 141 }, "evidence": [ { "id": "A0A5G2QTK2", "url": "https://omabrowser.org/oma/group/A0A5G2QTK2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DB42-1", "protein_name": "Zinc finger protein 593", "gene_name": "Znf593", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRSRRTGAHRAHSLARQMKAKKRRPDLDEIHRELRPQGLPRPKPEPDAEPDPDLPGGGLHRCLACARYFIDSANLKTHFRSKDHKKRLKQLSVEPYSQEEAERAAGMGSYVQPQRLGVPTEVSTDIPEMDTST", "length": 134 }, "evidence": [ { "id": "A0A5G2QTK2", "url": "https://omabrowser.org/oma/group/A0A5G2QTK2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W3Y0-1", "protein_name": "Zinc finger protein 593 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGMVSKRKKMHYGDTHLQRRWRVRNRRRDLDQIDDDLQTRSGELINQNVDLDKPGFAQFYCVHCAKYFIDDTAMQAHFRTKVHKRRLKALEIEPYSIEEAERAAGRGSFVKPKKRAMETQPSKEDVVAGKRIRVEVVPEDTDATDSPSTSKTKRKKVEKMET", "length": 162 }, "evidence": [ { "id": "A0A5G2QTK2", "url": "https://omabrowser.org/oma/group/A0A5G2QTK2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "preribosome binding", "id": "GO:1990275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990275", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2" } ], "pmid": "" }, { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QTK2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 134, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QTK2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTK2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QTK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTK2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 90, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QTM9-1", "uniprot_ac": "A0A5G2QTM9", "uniprot_id": "A0A5G2QTM9_PIG", "mass": { "chemical_mass": 49043.0, "monoisotopic_mass": 49043.0 }, "refseq": {}, "gene_names": [ { "name": "TMPRSS3", "type": "recommended", "evidence": [ { "id": "A0A5G2QTM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9" } ] } ], "protein_names": [ { "name": "Transmembrane protease serine 3", "type": "recommended", "evidence": [ { "id": "A0A5G2QTM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival. Activates ENaC (in vitro).", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9#function" }, { "database": "UniProtKB", "id": "ARBA00056942", "url": "https://www.uniprot.org/uniprotkb/ARBA00056942#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMPRSS3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9", "locus": { "chromosome": "13", "start_pos": 205709663, "end_pos": 205732824, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000022568", "url": "https://www.ensembl.org/id/ENSSSCG00000022568" } ] } } ], "crossref": [ { "id": "A0A5G2QTM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000022568", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022568", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15494", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15494", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QTM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY63", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY63-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGENDPPAAEAPFSFRSLFGLDDLKISPVAPDADAVAAQILSLLPLKFFPILVVGIIALILALAIGLGIHFDCSGKYRCRSSFKCIELAARCNGVADCREGEDEYRCVRVSGRNAALQVFTAAAWRTVCSEDWKAHHASVACAQLGFPSYVSSDTLRVDLLEEPFREDFVSINHLLPDDKVTALHHAVYVREGCASGHVVTLTCSACGRRMGSSPRIVGGNASSLAQWPWQASLQFQGYHLCGGSVITPVWVVTAAHCVYDLYLPKSWTIQVGLVSLLDSPAPSHLVEKIIYHSKYKPKRLGNDIALMKLAGPVAFNEMIQPVCLPNSEENFPDGKMCWTSGWGATEDGAGDASPVLNHAAVPLLSNKLCNHRDVYGGLISPSMLCAGYLKGGVDSCQGDSGGPLVCQERTVWKLVGATSFGIGCAEANKPGVYTRITSFLDWIHEQMERDLKT", "length": 454, "header": "tr|A0A5G2QTM9-1|A0A5G2QTM9_PIG Isoform 1 of Transmembrane protease serine 3 OS=Sus scrofa OX=9823 GN=TMPRSS3 PE=4 SV=1 CANONICAL=A0A5G2QTM9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QTM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9/entry#A0A5G2QTM9-1", "sequence": { "sequence": "MGENDPPAAEAPFSFRSLFGLDDLKISPVAPDADAVAAQILSLLPLKFFPILVVGIIALILALAIGLGIHFDCSGKYRCRSSFKCIELAARCNGVADCREGEDEYRCVRVSGRNAALQVFTAAAWRTVCSEDWKAHHASVACAQLGFPSYVSSDTLRVDLLEEPFREDFVSINHLLPDDKVTALHHAVYVREGCASGHVVTLTCSACGRRMGSSPRIVGGNASSLAQWPWQASLQFQGYHLCGGSVITPVWVVTAAHCVYDLYLPKSWTIQVGLVSLLDSPAPSHLVEKIIYHSKYKPKRLGNDIALMKLAGPVAFNEMIQPVCLPNSEENFPDGKMCWTSGWGATEDGAGDASPVLNHAAVPLLSNKLCNHRDVYGGLISPSMLCAGYLKGGVDSCQGDSGGPLVCQERTVWKLVGATSFGIGCAEANKPGVYTRITSFLDWIHEQMERDLKT", "length": 454, "header": "tr|A0A5G2QTM9-1|A0A5G2QTM9_PIG Isoform 1 of Transmembrane protease serine 3 OS=Sus scrofa OX=9823 GN=TMPRSS3 PE=4 SV=1 CANONICAL=A0A5G2QTM9-1" }, "locus": { "chromosome": "13", "start_pos": 205731992, "end_pos": 205712568, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089050.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089050.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065350.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065350.1" } ] } }, { "isoform_ac": "A0A5G2QY63-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9/entry#A0A5G2QY63-1", "sequence": { "sequence": "MGENDPPAAEAPFSFRSLFGLDDLKISPVAPDADAVAAQILSLLPLKFFPILVVGIIALILALAIGLGIHFDCSGKYRCRSSFKCIELAARCNGVADCREGEDEYRCVRVSGRNAALQVFTAAAWRTVCSEDWKAHHASVACAQLGFPSYVSSDTLRVDLLEEPFREDFVSINHLLPDDKVTALHHAVYVREGCASGHVVTLTCSACGRRMGSSPRIVGGNASSLAQWPWQASLQFQGYHLCGGSVITPVWVVTAAHCVYDLYLPKSWTIQVGLVSLLDSPAPSHLVEKIIYHSKYKPKRLGNDIALMKLAGPVAFNGKWGFLCHCVARLFRENVLLAEAWRR", "length": 343, "header": "tr|A0A5G2QY63-1|A0A5G2QTM9_PIG Computationally mapped isoform of Transmembrane protease serine 3 OS=Sus scrofa OX=9823 GN=TMPRSS3 PE=4 SV=1 CANONICAL=A0A5G2QTM9-1" }, "locus": { "chromosome": "13", "start_pos": 205731992, "end_pos": 205718676, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090189.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090189.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063148.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063148.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY63", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY63" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9" } ], "pmid": "" }, { "name": "sodium channel regulator activity", "id": "GO:0017080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017080", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QTM9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 454, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QTM9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTM9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QTM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 217, "end_pos": 449, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QTM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTM9" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 105, "end_pos": 205, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 221, "end_pos": 223 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QTY9-1", "uniprot_ac": "A0A5G2QTY9", "uniprot_id": "A0A5G2QTY9_PIG", "mass": { "chemical_mass": 45478.0, "monoisotopic_mass": 45478.0 }, "refseq": {}, "gene_names": [ { "name": "CFP", "type": "recommended", "evidence": [ { "id": "A0A5G2QTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ] }, { "name": "ELK1", "type": "synonym", "evidence": [ { "id": "A0A5G2QTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ] } ], "protein_names": [ { "name": "ETS domain-containing protein Elk-1", "type": "recommended", "evidence": [ { "id": "A0A5G2QTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2. Induces target gene transcription upon JNK and MAPK-signaling pathways stimulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9#function" }, { "database": "UniProtKB", "id": "ARBA00055801", "url": "https://www.uniprot.org/uniprotkb/ARBA00055801#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CFP", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9", "locus": { "chromosome": "X", "start_pos": 42143697, "end_pos": 42152868, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012278", "url": "https://www.ensembl.org/id/ENSSSCG00000012278" } ] } } ], "crossref": [ { "id": "A0A5G2QTY9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012278", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012278", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "8ZH9", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZH9&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008zh9", "url": "https://www.rcsb.org/structure/pdb_00008zh9", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZH9", "url": "https://www.rcsb.org/structure/8ZH9", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QTN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSAEDCPAQPEVAVTSAVASAGPAAVHAVPGDTASGKPGTPKGAGMAGPGGLARSSRNDYMRSGLYSTFTIQSLQPQPQPPASHPRPSTVLPNATPAGAAVPPSGSRSTSPSPLEACLEAEEASLPLQVILTPPEAPNLKSEEPNMEPGLGRPLPPEVKVEEPKEELEAAASGEAGFVLEAVKAEPEIPPAEGVPARLPAVLMETAAQVGGLAASTTSSTEIAQPQKGRKPRDLELPLSPSLLGGPGSERTPGSGTGSGLQAPGPALTPSLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVVLSPGPQKP", "length": 436, "header": "tr|A0A5G2QTY9-1|A0A5G2QTY9_PIG Isoform 1 of ETS domain-containing protein Elk-1 OS=Sus scrofa OX=9823 GN=CFP PE=3 SV=1 CANONICAL=A0A5G2QTY9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QTN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9/entry#A0A5G2QTN4-1", "sequence": { "sequence": "MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYDKNIIRKVSGQKFVYKFVSYPESHCTP", "length": 95, "header": "tr|A0A5G2QTN4-1|A0A5G2QTY9_PIG Computationally mapped isoform of ETS domain-containing protein Elk-1 OS=Sus scrofa OX=9823 GN=CFP PE=3 SV=1 CANONICAL=A0A5G2QTY9-1" }, "locus": { "chromosome": "X", "start_pos": 42166779, "end_pos": 42159636, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079241.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079241.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067513.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067513.1" } ] } }, { "isoform_ac": "A0A5G2QTY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9/entry#A0A5G2QTY9-1", "sequence": { "sequence": "MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSAEDCPAQPEVAVTSAVASAGPAAVHAVPGDTASGKPGTPKGAGMAGPGGLARSSRNDYMRSGLYSTFTIQSLQPQPQPPASHPRPSTVLPNATPAGAAVPPSGSRSTSPSPLEACLEAEEASLPLQVILTPPEAPNLKSEEPNMEPGLGRPLPPEVKVEEPKEELEAAASGEAGFVLEAVKAEPEIPPAEGVPARLPAVLMETAAQVGGLAASTTSSTEIAQPQKGRKPRDLELPLSPSLLGGPGSERTPGSGTGSGLQAPGPALTPSLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVVLSPGPQKP", "length": 436, "header": "tr|A0A5G2QTY9-1|A0A5G2QTY9_PIG Isoform 1 of ETS domain-containing protein Elk-1 OS=Sus scrofa OX=9823 GN=CFP PE=3 SV=1 CANONICAL=A0A5G2QTY9-1" }, "locus": { "chromosome": "X", "start_pos": 42166779, "end_pos": 42159420, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066766.1", "url": "https://www.ensembl.org/id/ENSSSCT00000066766.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068406.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068406.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTN4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Host genetic variation governs PCV2 susceptibility through CXCL13 and ELK1-mediated immune regulation.", "journal": "Int. J. Biol. Macromol.", "date": "2025", "authors": "Gao F., Gao Y., Li X., Liu G., Sun L., Sun Y., Wang W., Wu Y., Yang N., Jiang Y., Cheng Y., Shu Y., Zhou Z.W.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTN4" } ], "reference": [ { "type": "PubMed", "id": "40267997", "url": "https://glygen.org/publication/PubMed/40267997" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" }, { "name": "mediator complex binding", "id": "GO:0036033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036033", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" }, { "name": "transcription regulator activator activity", "id": "GO:0140537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140537", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QTY9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 436, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QTY9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTY9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTY9" }, { "id": "PS50061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ETS", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 86, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QTP8-1", "uniprot_ac": "A0A5G2QTP8", "uniprot_id": "A0A5G2QTP8_PIG", "mass": { "chemical_mass": 40565.0, "monoisotopic_mass": 40565.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110260994", "type": "recommended", "evidence": [ { "id": "A0A5G2QTP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTP8" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QTP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTP8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTP8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110260994", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTP8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QTP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000024568", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000024568", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05774", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05774", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050831", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050831", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR44427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44427:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44427:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QTP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GRKDSRAHTSDSSACGPFWSGNSSLTGRDTAGTRHHGAPLSPWPQRACPLAQAPAGSLTPDLLEPAHHCQITVESVTFNAVEGRNILLLVHNAIENILAYHWYRGERIKNSQLIASYEVDRQVTITGPAHSGREIIYPNGSLLFQKVNQNDTGYYTLSIIYNDLQTESVIKQLYVYPPVAKPIIEASNTTGTEHGVTVVLKCLTNDTGVAISWFFNGQSLLLTERMELSQDNSTLTIEPVRREDAGDYQCEISNLIGSSKSDPSRVDVILQENGPVLSVGAIVGIVIGVLVVVALVAALGCFIFLARIRSPGCLQNSRENWYIESTPGYGPSSSSLSPACLSDRMPEVPIYQELVHPDTDIYCGMDHKADVAS", "length": 373, "header": "tr|A0A5G2QTP8-1|A0A5G2QTP8_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110260994 PE=3 SV=1 CANONICAL=A0A5G2QTP8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QTP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTP8/entry#A0A5G2QTP8-1", "sequence": { "sequence": "GRKDSRAHTSDSSACGPFWSGNSSLTGRDTAGTRHHGAPLSPWPQRACPLAQAPAGSLTPDLLEPAHHCQITVESVTFNAVEGRNILLLVHNAIENILAYHWYRGERIKNSQLIASYEVDRQVTITGPAHSGREIIYPNGSLLFQKVNQNDTGYYTLSIIYNDLQTESVIKQLYVYPPVAKPIIEASNTTGTEHGVTVVLKCLTNDTGVAISWFFNGQSLLLTERMELSQDNSTLTIEPVRREDAGDYQCEISNLIGSSKSDPSRVDVILQENGPVLSVGAIVGIVIGVLVVVALVAALGCFIFLARIRSPGCLQNSRENWYIESTPGYGPSSSSLSPACLSDRMPEVPIYQELVHPDTDIYCGMDHKADVAS", "length": 373, "header": "tr|A0A5G2QTP8-1|A0A5G2QTP8_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110260994 PE=3 SV=1 CANONICAL=A0A5G2QTP8-1" }, "locus": { "chromosome": "6", "start_pos": 50158683, "end_pos": 50148061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071878.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071878.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067528.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067528.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 326, "start_aa": "Thr", "end_pos": 326, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr326", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTP8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTP8" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QTP8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 373, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QTP8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTP8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QTP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTP8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 177, "end_pos": 267, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 326 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 22, "end_pos": 24 }, { "start_pos": 232, "end_pos": 234 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QTQ5-1", "uniprot_ac": "A0A5G2QTQ5", "uniprot_id": "A0A5G2QTQ5_PIG", "mass": { "chemical_mass": 43586.0, "monoisotopic_mass": 43586.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QTQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTQ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000042971", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042971", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QTQ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6S4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6S4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHAPSEIQHVSPKDAPTGSDSSTTSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGFRMKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWLSMSQRISNITTPTRSGLSSPSSPSVRPPGQIAMAQHAIFNQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHLISNFPSGYFGLRVEPSPLPTRYQNISPTEGPLSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSISEHHPNYH", "length": 391, "header": "tr|A0A5G2QTQ5-1|A0A5G2QTQ5_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QTQ5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QTQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5/entry#A0A5G2QTQ5-1", "sequence": { "sequence": "MAHAPSEIQHVSPKDAPTGSDSSTTSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGFRMKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWLSMSQRISNITTPTRSGLSSPSSPSVRPPGQIAMAQHAIFNQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHLISNFPSGYFGLRVEPSPLPTRYQNISPTEGPLSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSISEHHPNYH", "length": 391, "header": "tr|A0A5G2QTQ5-1|A0A5G2QTQ5_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QTQ5-1" }, "locus": { "chromosome": "Y", "start_pos": 19887404, "end_pos": 19885777, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103607.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103607.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074629.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074629.1" } ] } }, { "isoform_ac": "A0A8W4F6S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5/entry#A0A8W4F6S4-1", "sequence": { "sequence": "MAHAPSEIQHVSPKDAPTGSDSSTTSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGFRMKNASPVSASLLQGCSKKQTRGEDAFSTSTNLNVPLIRWLSMSQRISNITTPTRSGLSSPSSPSVRPPGQIAMAQHAIFNQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHLISNFPSGYFGLRVEPSPLPTRYQNISPTEGPLSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSISEHHPNYH", "length": 374, "header": "tr|A0A8W4F6S4-1|A0A5G2QTQ5_PIG Computationally mapped isoform of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QTQ5-1" }, "locus": { "chromosome": "Y", "start_pos": 21984616, "end_pos": 21982989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100398.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100398.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076264.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076264.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 345, "start_aa": "Thr", "end_pos": 345, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr345", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTQ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTQ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTQ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTQ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTQ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QTQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ5" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 162, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 345 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 250, "end_pos": 252 }, { "start_pos": 341, "end_pos": 343 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2QTR7-1", "uniprot_ac": "A0A5G2QTR7", "uniprot_id": "A0A5G2QTR7_PIG", "mass": { "chemical_mass": 85463.0, "monoisotopic_mass": 85463.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Disintegrin and metalloproteinase domain-containing protein 5-like", "type": "recommended", "evidence": [ { "id": "A0A5G2QTR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7", "locus": {} } ], "crossref": [ { "id": "A0A5G2QTR7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015806", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015806", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QTR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZL6", "url": "https://www.uniprot.org/uniprotkb/F1RZL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZL6-1", "url": "https://www.uniprot.org/uniprotkb/F1RZL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLLLVLLTGLGGLHAGLSPHKTFLHTTVPEKISSSEAIKNPENNVAYIITIEGKPYFVHLKKQLFLSSASVVYSYDKNDIQHSQPLSAQMDCSYHGYIAGFPNSLVSLNTCSGLRGTLQFKNFSYGIEPVETISGFMHMIYEEKNNSTDIPLLWNNDINSYERLQYQVRKSSELFPLYLDMYIVVDKNLFDYMGSDIKSVTQKVIQIIGFVNTMLTQLKLTVRISAIDIWSNKNKISTAGSPDYVLYKFLEWKYRFLFQPHHTAYLLAFKKHPVFIGVTHPGKICDKSDAGGVALYPEGLSLESYSINIIQLVGLNLGMSYDNTEICHCSGDVCIMSPEAMHSGGVKDFSTCSLDDFKYFAAHSGLTCLHSILLDEPVYKQRRRICGNGILEQGEQCDCGTLENCTHKHCCDPRTCRRKRNKQCGSGECCTQDCKIRPANVICRKSADECDFIEYCNGTYSHCVADTFARNGQSCESGSAYCYGGRCRSFTKQCRNLIGGESTGASFSCFDEINSRKDRFGNCGREYCNYPHLLCGKLVCNWPHKYLISRANLSVIYSHVREQMCVSTFLNAEKIPRDTITTVQFPGDRDRTFVQDGTVCGPEMFCLNFSCVEIKYRVNYGECNSSRHCNANGVCNNFNHCHCKKGFVPPDCNVGNGFGSIDDGHQSKVGYIMSSANSDSFTSSFPIWIPFISFTSLIAMARTSKTMLKSSGESGHPCLVADLSGNSFSFSPLRMMLAVGLSCMLFYYVDDHYTTTDVINSFA", "length": 764, "header": "tr|A0A5G2QTR7-1|A0A5G2QTR7_PIG Isoform 1 of Disintegrin and metalloproteinase domain-containing protein 5-like OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A5G2QTR7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QTR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7/entry#A0A5G2QTR7-1", "sequence": { "sequence": "MFLLLVLLTGLGGLHAGLSPHKTFLHTTVPEKISSSEAIKNPENNVAYIITIEGKPYFVHLKKQLFLSSASVVYSYDKNDIQHSQPLSAQMDCSYHGYIAGFPNSLVSLNTCSGLRGTLQFKNFSYGIEPVETISGFMHMIYEEKNNSTDIPLLWNNDINSYERLQYQVRKSSELFPLYLDMYIVVDKNLFDYMGSDIKSVTQKVIQIIGFVNTMLTQLKLTVRISAIDIWSNKNKISTAGSPDYVLYKFLEWKYRFLFQPHHTAYLLAFKKHPVFIGVTHPGKICDKSDAGGVALYPEGLSLESYSINIIQLVGLNLGMSYDNTEICHCSGDVCIMSPEAMHSGGVKDFSTCSLDDFKYFAAHSGLTCLHSILLDEPVYKQRRRICGNGILEQGEQCDCGTLENCTHKHCCDPRTCRRKRNKQCGSGECCTQDCKIRPANVICRKSADECDFIEYCNGTYSHCVADTFARNGQSCESGSAYCYGGRCRSFTKQCRNLIGGESTGASFSCFDEINSRKDRFGNCGREYCNYPHLLCGKLVCNWPHKYLISRANLSVIYSHVREQMCVSTFLNAEKIPRDTITTVQFPGDRDRTFVQDGTVCGPEMFCLNFSCVEIKYRVNYGECNSSRHCNANGVCNNFNHCHCKKGFVPPDCNVGNGFGSIDDGHQSKVGYIMSSANSDSFTSSFPIWIPFISFTSLIAMARTSKTMLKSSGESGHPCLVADLSGNSFSFSPLRMMLAVGLSCMLFYYVDDHYTTTDVINSFA", "length": 764, "header": "tr|A0A5G2QTR7-1|A0A5G2QTR7_PIG Isoform 1 of Disintegrin and metalloproteinase domain-containing protein 5-like OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A5G2QTR7-1" }, "locus": { "chromosome": "15", "start_pos": 47376269, "end_pos": 47306538, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076157.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076157.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068233.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068233.2" } ] } }, { "isoform_ac": "F1RZL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7/entry#F1RZL6-1", "sequence": { "sequence": "KLNHLDYFLFLPGTTLLSNVINIHEISRMSILKMDCSYHGYIAGFPNSLVSLNTCSGLRGTLQFKNFSYGIEPVETISGFMHMIYEEKNNSTDIPLLWNNDINSYERLQYQVRKSSEKPDYFKLFPLYLDMYIVVDKNLFDYMGSDIKSVTQKVIQIIGFVNTMLTQLKLTVRISAIDIWSNKNKISTAGSPDYVLYKFLEWKYRFLFQPHHTAYLLAFKKHPVFIGVTHPGKICDKSDAGGVALYPEGLSLESYSINIIQLVGLNLGMSYDNTEICHCSGDVCIMSPEAMHSGGVKDFSTCSLDDFKYFAAHSGLTCLHSILLDEPVYKQRRRICGNGILEQGEQCDCGTLENCTHKHCCDPRTCRRKRNKQCGSGECCTQDCKIRPANVICRKSADECDFIEYCNGTYSHCVADTFARNGQSCESGSAYCYGGRCRSFTKQCRNLIGGESTGASFSCFDEINSRKDRFGNCGREYCNYPHLLCGKLVCNWPHKYLISRANLSVIYSHVREQMCVSTFLNAEKIPRDTITTVQFPGDRDRTFVQDGTVCGPEMVIRMKIFKFNYGECNSSRHCNANGVCNNFNHCHCKKGFVPPDCNVGNGFGSIDDGHQSKVESLGFSRYSIMSSANSDSFTSSFPIWIPFISFTSLIAMARTSKTMLKSSGESGHPCLVADLSGNSFSFSPLRMMLAVGLSCMLFYYVDDHYTTTDVINSFA", "length": 715, "header": "tr|F1RZL6-1|A0A5G2QTR7_PIG Computationally mapped isoform of Disintegrin and metalloproteinase domain-containing protein 5-like OS=Sus scrofa OX=9823 GN= PE=4 SV=5 CANONICAL=A0A5G2QTR7-1" }, "locus": { "chromosome": "15", "start_pos": 47362990, "end_pos": 47306538, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017214.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017214.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016753.5", "url": "https://www.ensembl.org/id/ENSSSCP00000016753.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZL6", "url": "https://www.uniprot.org/uniprotkb/F1RZL6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7" } ], "pmid": "" }, { "name": "binding of sperm to zona pellucida", "id": "GO:0007339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007339", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QTR7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 764, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QTR7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTR7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QTR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7" }, { "id": "PS50214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Disintegrin", "eco_id": "ECO_0000259", "start_pos": 384, "end_pos": 472, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QTR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 620, "end_pos": 654, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QTR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTR7" }, { "id": "PS50215", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50215" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M12B", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 374, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 147, "end_pos": 149 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 458, "end_pos": 460 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 625, "end_pos": 627 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QTU0-1", "uniprot_ac": "A0A5G2QTU0", "uniprot_id": "A0A5G2QTU0_PIG", "mass": { "chemical_mass": 75797.0, "monoisotopic_mass": 75797.0 }, "refseq": {}, "gene_names": [ { "name": "DNAJC16", "type": "recommended", "evidence": [ { "id": "A0A5G2QTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0" } ] } ], "protein_names": [ { "name": "DnaJ homolog subfamily C member 16", "type": "recommended", "evidence": [ { "id": "A0A5G2QTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0/entry#names_and_taxonomy" } ] }, { "name": "Endoplasmic reticulum DNA J domain-containing protein 8", "type": "synonym", "evidence": [ { "id": "A0A5G2QTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays an important role in regulating the size of autophagosomes during the formation process.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTU0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0#function" }, { "database": "UniProtKB", "id": "ARBA00035002", "url": "https://www.uniprot.org/uniprotkb/ARBA00035002#function" }, { "database": "UniProtKB", "id": "F1SUU5", "url": "https://www.uniprot.org/uniprotkb/F1SUU5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTU0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DNAJC16", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0", "locus": { "chromosome": "6", "start_pos": 74774311, "end_pos": 74732169, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003464", "url": "https://www.ensembl.org/id/ENSSSCG00000003464" } ] } } ], "crossref": [ { "id": "A0A5G2QTU0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTU0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003464", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003464", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02963", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02963", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR44303", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44303", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44303:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44303:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26968", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26968", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QTU0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SUU5", "url": "https://www.uniprot.org/uniprotkb/F1SUU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SUU5-1", "url": "https://www.uniprot.org/uniprotkb/F1SUU5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVKKLSISWQFLIVLVLILQILSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDKFIQISKAYEILSNEEKRSHYDHYGDAGENQGYQKQQQQREYHFRHFHENFYFDESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPVWKEVVQELEGLGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHNAVVRENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHVLLFDQMPAVPLLYKLTAFAYKDYLSFGYVYVGLRGAEEMARQYNVNVYTPTILIFKEHIHKPADVIQARGVKKQVIDDFITQNKYLLAARLTSQKVFHELCPVKRSHRQRKYCVVLLTAEATKLSQPFEAFLSFALANTQDTVRFVHVYSNRQQEFADTLLPDSNAFQGKSAVSILERRNTAGRVVYKTLEDPWTGSESDKFILLGYLDQLRKDPALLSSEAVLPDLTDELAPIFLLRWLYSASDYISDCWDSIFHNNWREMMPLLSLVFSALFILFGTVIIQAFSDSNDERESNPPDKEEAHAKTGKTEPSFTKEPSSKIPKKGFVEVTELTDVTYTSNLVRLRPGHMNVVLILSSSTKTSLLQKFALEVYTFTGRIVWRR", "length": 656, "header": "tr|A0A5G2QTU0-1|A0A5G2QTU0_PIG Isoform 1 of DnaJ homolog subfamily C member 16 OS=Sus scrofa OX=9823 GN=DNAJC16 PE=4 SV=1 CANONICAL=A0A5G2QTU0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QTU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0/entry#A0A5G2QTU0-1", "sequence": { "sequence": "MEVKKLSISWQFLIVLVLILQILSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDKFIQISKAYEILSNEEKRSHYDHYGDAGENQGYQKQQQQREYHFRHFHENFYFDESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPVWKEVVQELEGLGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHNAVVRENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHVLLFDQMPAVPLLYKLTAFAYKDYLSFGYVYVGLRGAEEMARQYNVNVYTPTILIFKEHIHKPADVIQARGVKKQVIDDFITQNKYLLAARLTSQKVFHELCPVKRSHRQRKYCVVLLTAEATKLSQPFEAFLSFALANTQDTVRFVHVYSNRQQEFADTLLPDSNAFQGKSAVSILERRNTAGRVVYKTLEDPWTGSESDKFILLGYLDQLRKDPALLSSEAVLPDLTDELAPIFLLRWLYSASDYISDCWDSIFHNNWREMMPLLSLVFSALFILFGTVIIQAFSDSNDERESNPPDKEEAHAKTGKTEPSFTKEPSSKIPKKGFVEVTELTDVTYTSNLVRLRPGHMNVVLILSSSTKTSLLQKFALEVYTFTGRIVWRR", "length": 656, "header": "tr|A0A5G2QTU0-1|A0A5G2QTU0_PIG Isoform 1 of DnaJ homolog subfamily C member 16 OS=Sus scrofa OX=9823 GN=DNAJC16 PE=4 SV=1 CANONICAL=A0A5G2QTU0-1" }, "locus": { "chromosome": "6", "start_pos": 74774311, "end_pos": 74734521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078226.1", "url": "https://www.ensembl.org/id/ENSSSCT00000078226.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068263.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068263.1" } ] } }, { "isoform_ac": "F1SUU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0/entry#F1SUU5-1", "sequence": { "sequence": "MEVKKLSISWQFLIVLVLILQILSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDKFIQISKAYEILSNEEKRSHYDHYGDAGENQGYQKQQQQREYHFRHFHENFYFDESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPVWKEVVQELEGLGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHNAVVRENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHVLLFDQMPAVPLLYKLTAFAYKDYLSFGYVYVGLRGAEEMARQYNVNVYTPTILIFKEHIHKPADVIQARGVKKQVIDDFITQNKYLLAARLTSQKVFHELCPVKRSHRQRKYCVVLLTAEATKLSQPFEAFLSFALANTQDTVRFVHVYSNRQQEFADTLLPDSNAFQGKSAVSILERRNTAGRVVYKTLEDPWTGSESDKFILLGYLDQLRKDPALLSSEAVLPDLTDELAPIFLLRWLYSASDYISDCWDSIFHNNWREMMPLLSLVFSALFILFGTVIIQAFSDSNDERESNPPDKEEAHAKTGKTEPSFTKEPSRLL", "length": 595, "header": "tr|F1SUU5-1|F1SUU5_PIG Computationally mapped isoform of DnaJ homolog subfamily C member 16 OS=Sus scrofa OX=9823 GN=DNAJC16 PE=4 SV=2 CANONICAL=A0A5G2QTU0-1" }, "locus": { "chromosome": "6", "start_pos": 74765376, "end_pos": 74734521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003850.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003850.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003762.3", "url": "https://www.ensembl.org/id/ENSSSCP00000003762.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTU0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTU0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of autophagosome size", "id": "GO:0016243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016243", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTU0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTU0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QTU0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 656, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QTU0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTU0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 93, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTU0" }, { "id": "PS51352", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 247, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QTX1-1", "uniprot_ac": "A0A5G2QTX1", "uniprot_id": "A0A5G2QTX1_PIG", "mass": { "chemical_mass": 34922.0, "monoisotopic_mass": 34922.0 }, "refseq": { "ac": "XP_013834970", "name": "olfactory receptor 8B3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834970" }, "gene_names": [ { "name": "LOC106504908", "type": "synonym", "evidence": [ { "id": "XP_013834970", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834970" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QTX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8B3-like", "type": "synonym", "evidence": [ { "id": "XP_013834970", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834970" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTX1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTX1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1", "locus": {} } ], "crossref": [ { "id": "A0A5G2QTX1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000043498", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000043498", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15405", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15405", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "106504908", "url": "https://www.ncbi.nlm.nih.gov/gene/106504908", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:106504908", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106504908", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GSYMMAF", "url": "https://omabrowser.org/oma/group/GSYMMAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QTX1", "url": "https://www.orthodb.org/?gene=A0A5G2QTX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013834970", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834970", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QTX1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPGNGSFVTDFILVGLTDHPALQLPLFLLFLVMYMVTVLGNFGLITVIGLNSHLHTPMYLFLFNLSFIDLCYSSVFTPKMLTHFLSENKLISYLGCMTQLYFFCFFGISEAYVLTAMAYDRYVAICNPLLYNIAMSPKVCSSLMLACYLMALSGAMAHTGCMLRLTFCDANTINHYLCDILPLLQLSWTSTYINEMVDFITVGINIIVPSLTIFVSYGLILSNILRISSMESRSKAFSTCSSHIIAVSLFFGSGAIMYLRPSSSGSMDKGKISSVFYTNVVPMMNPLIYSLRNKDVKFALRKTLRRRFRF", "length": 311, "header": "tr|A0A5G2QTX1-1|A0A5G2QTX1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QTX1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QTX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1/entry#A0A5G2QTX1-1", "sequence": { "sequence": "MAPGNGSFVTDFILVGLTDHPALQLPLFLLFLVMYMVTVLGNFGLITVIGLNSHLHTPMYLFLFNLSFIDLCYSSVFTPKMLTHFLSENKLISYLGCMTQLYFFCFFGISEAYVLTAMAYDRYVAICNPLLYNIAMSPKVCSSLMLACYLMALSGAMAHTGCMLRLTFCDANTINHYLCDILPLLQLSWTSTYINEMVDFITVGINIIVPSLTIFVSYGLILSNILRISSMESRSKAFSTCSSHIIAVSLFFGSGAIMYLRPSSSGSMDKGKISSVFYTNVVPMMNPLIYSLRNKDVKFALRKTLRRRFRF", "length": 311, "header": "tr|A0A5G2QTX1-1|A0A5G2QTX1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QTX1-1" }, "locus": { "chromosome": "9", "start_pos": 50839962, "end_pos": 50839030, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091008.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091008.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068386.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068386.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTX1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:106504908", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106504908", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3IF17-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100762275", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIPENGSSVTEFILVGLTKQPDLQCPLFILFLVMYVVTVLGNLGLIILIGLNSHLHTPMYFFLCNLSFVDLCYSSVFSPKMLMSFISEENIISYRGCMTQLFFFSFFSISECYVLTSMAYDRYVAICNPLMYNIVMSPKLCLNLMLGSYMMAFSGALAHTGCMLRLTFCDANTINHYFCDILPLLQISCTSTYVNELEVFVVVGINIIVPSITIFISYGFILSSIFHISSTEGRFKAFNTCSSHIIAVSLFFGSGAFMYLKPVTAMSMDEGKISSVFYTNTVPLLNPLIYSLRNKDVKVALIKTLSKRNC", "length": 310 }, "evidence": [ { "id": "A0A5G2QTX1", "url": "https://omabrowser.org/oma/group/A0A5G2QTX1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "L7N1X5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGFENGSSVTEFILVGLTKESDLQCPLFILFLMMYVVTVLGNQGLISLIGLNSHLHTPMYFFLFNLSFVDLWYSSVFTPKMLESFISEKNTISYRGCMAQLFFFCFFSISECYILTSMAYDRYVAICNPLLYNIVMSPKQCLILMFSSYMMAFSGAMAHTGCMLRLTFCDANTINHYFCDILPLLQLSCTSTYVNELEVFVVVGINIIVPTITIFISYGFIIASIFRISSKEDRSKAFSTCSSHIIAVSLFFGSGAFMYLKPSSAESMNEGKISSIFYTNTVPLLNPLIYSLRNKDVKDALIKTLSKRKR", "length": 310 }, "evidence": [ { "id": "A0A5G2QTX1", "url": "https://omabrowser.org/oma/group/A0A5G2QTX1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTX1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTX1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTX1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTX1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTX1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTX1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QTX1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QTX1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTX1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QTX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTX1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QTZ4-1", "uniprot_ac": "A0A5G2QTZ4", "uniprot_id": "A0A5G2QTZ4_PIG", "mass": { "chemical_mass": 117085.0, "monoisotopic_mass": 117085.0 }, "refseq": { "ac": "XP_020942274", "name": "protein CLEC16A isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942274" }, "gene_names": [ { "name": "CLEC16A", "type": "recommended", "evidence": [ { "id": "A0A5G2QTZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ] }, { "name": "CLEC16A", "type": "synonym", "evidence": [ { "id": "XP_020942274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942274" } ] } ], "protein_names": [ { "name": "C-type lectin domain containing 16A", "type": "synonym", "evidence": [ { "id": "A0A5G2QTZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4/entry#names_and_taxonomy" } ] }, { "name": "protein CLEC16A isoform X3", "type": "synonym", "evidence": [ { "id": "XP_020942274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942274" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CLEC16A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4", "locus": { "chromosome": "3", "start_pos": 31938135, "end_pos": 32158320, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026569", "url": "https://www.ensembl.org/id/ENSSSCG00000026569" } ] } } ], "crossref": [ { "id": "A0A5G2QTZ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTZ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026569", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026569", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100519828", "url": "https://www.ncbi.nlm.nih.gov/gene/100519828", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21481", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21481", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21481:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21481:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020942274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LTM5", "url": "https://www.uniprot.org/uniprotkb/I3LTM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LTM5-1", "url": "https://www.uniprot.org/uniprotkb/I3LTM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GRM8", "url": "https://www.uniprot.org/uniprotkb/K7GRM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GRM8-1", "url": "https://www.uniprot.org/uniprotkb/K7GRM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGRSRSWVGGGHGKSSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQRSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVSLDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLENQDKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSETYAKPEQDVQRSCAKPSIRCFIKPTETLERSLEMNKHKGKRRVQKRPNYKNVGEEEDEEKGPAEDAQEDAEKAKGTEGGSKGTKTSGENEEIEMVIMERSKLPELAAGTSVQEQNTTDEEKSAATGLESAQWSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLERIQLPVPSAAEKTAYNHLLAERLIRIMNSAAQPDGKIRLATLELSCLLLKQQVVTSTGCIIKDVHLACLEGAREESVHLVRHFYKGEEIFLDMFEDEYRSMTMKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGMLQRFLAVDIYQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFIFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEVLGFGLGSSSSQHLPFRFYDQCRRGSSDPTVQRSVFASVDKVPGFAVAQCINQHSSSSLSSPSPSASGSPSGSGSTSHCDSGGASSSSTPSAAQSPADELPTAEQPQPNLPDQLVIVSETEADTRPSKSLAKSADAEPVSLSPSLIPAQQPTISLLCEDTADTLSVESLTLVPPVDPCSLRTLAGIPPPPTPAVADTGAPGEGTAPQEPAGPAEH", "length": 1050, "header": "tr|A0A5G2QTZ4-1|A0A5G2QTZ4_PIG Isoform 1 of C-type lectin domain containing 16A OS=Sus scrofa OX=9823 GN=CLEC16A PE=3 SV=2 CANONICAL=A0A5G2QTZ4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QTZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4/entry#A0A5G2QTZ4-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKSSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQRSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVSLDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLENQDKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSETYAKPEQDVQRSCAKPSIRCFIKPTETLERSLEMNKHKGKRRVQKRPNYKNVGEEEDEEKGPAEDAQEDAEKAKGTEGGSKGTKTSGENEEIEMVIMERSKLPELAAGTSVQEQNTTDEEKSAATGLESAQWSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLERIQLPVPSAAEKTAYNHLLAERLIRIMNSAAQPDGKIRLATLELSCLLLKQQVVTSTGCIIKDVHLACLEGAREESVHLVRHFYKGEEIFLDMFEDEYRSMTMKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGMLQRFLAVDIYQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFIFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEVLGFGLGSSSSQHLPFRFYDQCRRGSSDPTVQRSVFASVDKVPGFAVAQCINQHSSSSLSSPSPSASGSPSGSGSTSHCDSGGASSSSTPSAAQSPADELPTAEQPQPNLPDQLVIVSETEADTRPSKSLAKSADAEPVSLSPSLIPAQQPTISLLCEDTADTLSVESLTLVPPVDPCSLRTLAGIPPPPTPAVADTGAPGEGTAPQEPAGPAEH", "length": 1050, "header": "tr|A0A5G2QTZ4-1|A0A5G2QTZ4_PIG Isoform 1 of C-type lectin domain containing 16A OS=Sus scrofa OX=9823 GN=CLEC16A PE=3 SV=2 CANONICAL=A0A5G2QTZ4-1" }, "locus": { "chromosome": "3", "start_pos": 32158139, "end_pos": 31940994, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069170.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069170.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068318.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068318.2" } ] } }, { "isoform_ac": "I3LTM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4/entry#I3LTM5-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKSSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQRSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLENQDKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSETYAKPEQDVQRSCAKPSIRCFIKPTETLERSLEMNKHKGKRRVQKRPNYKNVGEEEDEEKGPAEDAQEDAEKAKGTEGGSKGTKTSGENEEIEMVIMERSKLPELAAGTSVQEQNTTDEEKSAATGLESAQWSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLERIQLPVPSAAEKTAYNHLLAERLIRIMNSAAQPDGKIRLATLELSCLLLKQQVVTSTGCIIKDVHLACLEVRARLRPVPGPPGEREEMKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGMLQRFLAVDIYQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFIFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEVLGFGLGSSSSQHLPFRFYDQCRRGSSDPTVQRSVFASVDKVPGFAVAQCINQHSSSSLSSPSPSASGSPSGSGSTSHCDSGGASSSSTPSAAQSPADELPTAEQPQPNLPDQLVIVSETEADTRPSKSLAKSADAEPVSLSPSLIPAQQPTISLLCEDTADTLSVESLTLVPPVDPCSLRTLAGIPPPPTPAVADTGAPGEGTAPQEPAGPAEH", "length": 1033, "header": "tr|I3LTM5-1|A0A5G2QTZ4_PIG Computationally mapped isoform of C-type lectin domain containing 16A OS=Sus scrofa OX=9823 GN=CLEC16A PE=3 SV=3 CANONICAL=A0A5G2QTZ4-1" }, "locus": { "chromosome": "3", "start_pos": 32158139, "end_pos": 31940994, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024144.3", "url": "https://www.ensembl.org/id/ENSSSCT00000024144.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027472.3", "url": "https://www.ensembl.org/id/ENSSSCP00000027472.3" } ] } }, { "isoform_ac": "K7GRM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4/entry#K7GRM8-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKSSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQRSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLENQDKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSETYAKPEQDVQRSCAKPSIRCFIKPTETLERSLEMNKHKGKRRVQKRPNYKNVGEEEDEEKGPAEDAQEDAEKAKGTEGGSKGTKTSGENEEIEMVIMERSKLPELAAGTSVQEQNTTDEEKSAATGLESAQWSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLERIQLPVPSAAEKTAYNHLLAERLIRIMNSAAQPDGKIRLATLELSCLLLKQQVVTSTGCIIKDVHLACLEGAREESVHLVRHFYKGEEIFLDMFEDEYRSMTMKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGMLQRFLAVDIYQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFIFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEVLGFGLGSSSSQHLPFRFYDQCRRGSSDPTVQRSVFASVDKVPGFAVAQCINQHSSSSLSSPSPSASGSPSGSGSTSHCDSGGASSSSTPSAAQSPADELPTAEQPQPNLPDQLVIVSETEADTRPSKSLAKSADAEPVSLSPSLIPAQQPTISLLCEDTADTLSVESLTLVPPVDPCSLRTLAGIPPPPTPAVADTGAPGEGTAPQEPAGPAEH", "length": 1048, "header": "tr|K7GRM8-1|A0A5G2QTZ4_PIG Computationally mapped isoform of C-type lectin domain containing 16A OS=Sus scrofa OX=9823 GN=CLEC16A PE=3 SV=4 CANONICAL=A0A5G2QTZ4-1" }, "locus": { "chromosome": "3", "start_pos": 32158139, "end_pos": 31940994, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035852.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035852.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030556.4", "url": "https://www.ensembl.org/id/ENSSSCP00000030556.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1026, "start_aa": "Thr", "end_pos": 1026, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1026", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 924, "start_aa": "Thr", "end_pos": 924, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr924", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LTM5", "url": "https://www.uniprot.org/uniprotkb/I3LTM5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ], "pmid": "" }, { "name": "negative regulation of autophagosome maturation", "id": "GO:1901097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901097", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ], "pmid": "" }, { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ], "pmid": "" }, { "name": "regulation of autophagosome maturation", "id": "GO:1901096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901096", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 705, "end_pos": 707, "annotation": "n_glycosylation_sequon" }, { "start_pos": 770, "end_pos": 772, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QTZ4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1050, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QTZ4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QTZ4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QTZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" }, { "id": "PF19439", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19439" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CLEC16A/TT9 C-terminal", "eco_id": "ECO_0000259", "start_pos": 245, "end_pos": 1018, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QTZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ4" }, { "id": "PF09758", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09758" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FPL", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 198, "start_aa": "Ile", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 924, 1026 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 64, "end_pos": 66 }, { "start_pos": 705, "end_pos": 707 }, { "start_pos": 770, "end_pos": 772 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QU12-1", "uniprot_ac": "A0A5G2QU12", "uniprot_id": "A0A5G2QU12_PIG", "mass": { "chemical_mass": 72584.0, "monoisotopic_mass": 72584.0 }, "refseq": {}, "gene_names": [ { "name": "TNK1", "type": "recommended", "evidence": [ { "id": "A0A5G2QU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12" } ] } ], "protein_names": [ { "name": "Non-receptor tyrosine-protein kinase TNK1", "type": "recommended", "evidence": [ { "id": "A0A5G2QU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12/entry#names_and_taxonomy" } ] }, { "name": "2.7.10.2", "type": "synonym", "evidence": [ { "id": "A0A5G2QU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU12", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TNK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12", "locus": { "chromosome": "12", "start_pos": 52719096, "end_pos": 52711921, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026142", "url": "https://www.ensembl.org/id/ENSSSCG00000026142" } ] } } ], "crossref": [ { "id": "A0A5G2QU12", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU12", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026142", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026142", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09539", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09539", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24418", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24418", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28526", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28526", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QU12", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QU12-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPEADSLWLLRLLRDIQLAEFYRPILEALNVTRPEHFDFVRPEDLDGIGMGRPAQRRLVEALKRHRSGLKSKNWVYKILGGFAPGQKESTPPSDSPPSLPEPEGGLKCLIPDGAVCRGELLGSGCFGVVHRGLWTLPSGQSIPVAVKSLRVGPEGPEGTELGDFLREVSVMMNLEHPHVLRLHGLVLGQPLQMVMELAPLGSLHTRLTAPAPTPPLPVALLCLFLRQVAGAMAYLGARGLVHRDLATRNLLLASPRTVKVADFGLVRPLGGARGRYVMGGPRRIPFAWCAPESLRHGAFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPRPPLCSRALYALALRCWAPHPADRPSFSNLEGLLQEAWPPEGRCVRDVTEPGALRMEPGDPITIIEGSASPHSPDSTTWKGQNGRTFKMGNFPASAVTLVDSGGSPASHLLPRGAPARGEHHQGNISGDRAKAKLRDPPPAQGQRRNMALQRSKGISKSLESVLSLGPRPTGGGSSPPELRHARVGPQGAPGLPPRPPVAASSSSQPSQPPRERPPWPKRELPHSQPTGAPGASKATVPSRGPLPDFELQRRITEVELSVHGVTHQECQEALRATGGDVVAAIRNLKVDQLFYLSSWSRADCRRILERYQWDLSAASRYVLARS", "length": 668, "header": "tr|A0A5G2QU12-1|A0A5G2QU12_PIG Isoform 1 of Non-receptor tyrosine-protein kinase TNK1 OS=Sus scrofa OX=9823 GN=TNK1 PE=4 SV=1 CANONICAL=A0A5G2QU12-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QU12-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12/entry#A0A5G2QU12-1", "sequence": { "sequence": "MLPEADSLWLLRLLRDIQLAEFYRPILEALNVTRPEHFDFVRPEDLDGIGMGRPAQRRLVEALKRHRSGLKSKNWVYKILGGFAPGQKESTPPSDSPPSLPEPEGGLKCLIPDGAVCRGELLGSGCFGVVHRGLWTLPSGQSIPVAVKSLRVGPEGPEGTELGDFLREVSVMMNLEHPHVLRLHGLVLGQPLQMVMELAPLGSLHTRLTAPAPTPPLPVALLCLFLRQVAGAMAYLGARGLVHRDLATRNLLLASPRTVKVADFGLVRPLGGARGRYVMGGPRRIPFAWCAPESLRHGAFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPRPPLCSRALYALALRCWAPHPADRPSFSNLEGLLQEAWPPEGRCVRDVTEPGALRMEPGDPITIIEGSASPHSPDSTTWKGQNGRTFKMGNFPASAVTLVDSGGSPASHLLPRGAPARGEHHQGNISGDRAKAKLRDPPPAQGQRRNMALQRSKGISKSLESVLSLGPRPTGGGSSPPELRHARVGPQGAPGLPPRPPVAASSSSQPSQPPRERPPWPKRELPHSQPTGAPGASKATVPSRGPLPDFELQRRITEVELSVHGVTHQECQEALRATGGDVVAAIRNLKVDQLFYLSSWSRADCRRILERYQWDLSAASRYVLARS", "length": 668, "header": "tr|A0A5G2QU12-1|A0A5G2QU12_PIG Isoform 1 of Non-receptor tyrosine-protein kinase TNK1 OS=Sus scrofa OX=9823 GN=TNK1 PE=4 SV=1 CANONICAL=A0A5G2QU12-1" }, "locus": { "chromosome": "12", "start_pos": 52718447, "end_pos": 52713266, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090115.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090115.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065485.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065485.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 214, "start_aa": "Thr", "end_pos": 214, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr214", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 515, "start_aa": "Thr", "end_pos": 515, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr515", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU12", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU12", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU12", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU12", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU12", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU12", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU12", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QU12-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 668, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QU12-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU12" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 383, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU12" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 381, "end_pos": 446, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 214, 515 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 31, "end_pos": 33 }, { "start_pos": 469, "end_pos": 471 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QU17-1", "uniprot_ac": "A0A5G2QU17", "uniprot_id": "A0A5G2QU17_PIG", "mass": { "chemical_mass": 28210.0, "monoisotopic_mass": 28210.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17", "locus": {} } ], "crossref": [ { "id": "A0A5G2QU17", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU17", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QU17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QU17-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYFFLSHLAFSDISFSSVTVPKMLMNMQTQDQSISYAGCIAQMYFFIFFTVLDDFLLTSMAYDRYVAICHPLHYTTIMREGLCTLLVTVSWIHSSANALCHTLLLTQLSFCADNTIPHFFCDFGALLKLFCSDTSLNELVIFTVGLAVITLPLICILVSYGHIGATILKVPSTKGICKALSTCGSHLSVVSLYYGTIIGLYFVPSSSASSPKDTISSVMYTVVTPLLNPFIYSLRNRDMKGALEKLFHKAAVLSQ", "length": 255, "header": "tr|A0A5G2QU17-1|A0A5G2QU17_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QU17-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QU17-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17/entry#A0A5G2QU17-1", "sequence": { "sequence": "MYFFLSHLAFSDISFSSVTVPKMLMNMQTQDQSISYAGCIAQMYFFIFFTVLDDFLLTSMAYDRYVAICHPLHYTTIMREGLCTLLVTVSWIHSSANALCHTLLLTQLSFCADNTIPHFFCDFGALLKLFCSDTSLNELVIFTVGLAVITLPLICILVSYGHIGATILKVPSTKGICKALSTCGSHLSVVSLYYGTIIGLYFVPSSSASSPKDTISSVMYTVVTPLLNPFIYSLRNRDMKGALEKLFHKAAVLSQ", "length": 255, "header": "tr|A0A5G2QU17-1|A0A5G2QU17_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QU17-1" }, "locus": { "chromosome": "1", "start_pos": 262923351, "end_pos": 262922587, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042726.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042726.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067649.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067649.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QU17-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 255, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QU17-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU17" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU17" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 232, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QU24-1", "uniprot_ac": "A0A5G2QU24", "uniprot_id": "A0A5G2QU24_PIG", "mass": { "chemical_mass": 50882.0, "monoisotopic_mass": 50882.0 }, "refseq": { "ac": "XP_020928566", "name": "anomalous homeobox protein-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928566" }, "gene_names": [ { "name": "LOC102158190", "type": "recommended", "evidence": [ { "id": "A0A5G2QU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24" } ] }, { "name": "LOC102158190", "type": "synonym", "evidence": [ { "id": "XP_020928566", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928566" } ] } ], "protein_names": [ { "name": "Homeobox domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24/entry#names_and_taxonomy" } ] }, { "name": "anomalous homeobox protein-like", "type": "synonym", "evidence": [ { "id": "XP_020928566", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928566" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU24", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC102158190", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24", "locus": {} } ], "crossref": [ { "id": "A0A5G2QU24", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU24", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050121", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050121", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "102158190", "url": "https://www.ncbi.nlm.nih.gov/gene/102158190", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:102158190", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102158190", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QU24", "url": "https://www.orthodb.org/?gene=A0A5G2QU24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10390:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10390:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020928566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928566", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QU24", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QU24-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSFLQLLRGSGGAGPPLAELVTLAGRLCRDLQDDPEQVQPLVSAVLDSQLRLYLLDHADVALVCARALAQQEQHQAACRLLEGCRVPGGSAELVRLWNDIHYQLLRKRLGVAELTPVQKFRCRKRNPPPASLCPEGLKNRNFPREVRQKLQDFASGVSTNPSKAEREDLALETRLTTEQVYNWFANYRRRQRALAQRGAPAQEAAKDPRAREAGSQPADHPHLGRGSLDRPQGSAPPEESGPVQTQQTPQEPWKPLALSPDFSREEAVPMSLAPRSLQPGEMYPEGPGFHLAAVPPVCPGLGLCPLAAGSDVLDPSLAAPESWLMSLALVSSKEVSFQTGQLVHDPGLNFTTHPPDAAVATPAALGEPSPTGFAEPPSGSPANAGQEEGPGTHGGQAGGQPDGFLVTQPPLQASGFLLTQSPPELALAPPAFAGPLPTVELSQPLPSSQVQWPDAQASGDTFWGARMLLELSGGSLG", "length": 478, "header": "tr|A0A5G2QU24-1|A0A5G2QU24_PIG Isoform 1 of Homeobox domain-containing protein OS=Sus scrofa OX=9823 GN=LOC102158190 PE=4 SV=2 CANONICAL=A0A5G2QU24-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QU24-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24/entry#A0A5G2QU24-1", "sequence": { "sequence": "MQSFLQLLRGSGGAGPPLAELVTLAGRLCRDLQDDPEQVQPLVSAVLDSQLRLYLLDHADVALVCARALAQQEQHQAACRLLEGCRVPGGSAELVRLWNDIHYQLLRKRLGVAELTPVQKFRCRKRNPPPASLCPEGLKNRNFPREVRQKLQDFASGVSTNPSKAEREDLALETRLTTEQVYNWFANYRRRQRALAQRGAPAQEAAKDPRAREAGSQPADHPHLGRGSLDRPQGSAPPEESGPVQTQQTPQEPWKPLALSPDFSREEAVPMSLAPRSLQPGEMYPEGPGFHLAAVPPVCPGLGLCPLAAGSDVLDPSLAAPESWLMSLALVSSKEVSFQTGQLVHDPGLNFTTHPPDAAVATPAALGEPSPTGFAEPPSGSPANAGQEEGPGTHGGQAGGQPDGFLVTQPPLQASGFLLTQSPPELALAPPAFAGPLPTVELSQPLPSSQVQWPDAQASGDTFWGARMLLELSGGSLG", "length": 478, "header": "tr|A0A5G2QU24-1|A0A5G2QU24_PIG Isoform 1 of Homeobox domain-containing protein OS=Sus scrofa OX=9823 GN=LOC102158190 PE=4 SV=2 CANONICAL=A0A5G2QU24-1" }, "locus": { "chromosome": "14", "start_pos": 22469999, "end_pos": 22457087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084483.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084483.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068353.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068353.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 362, "start_aa": "Thr", "end_pos": 362, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr362", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU24", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102158190", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102158190", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU24", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU24", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU24", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU24", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU24", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QU24-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 478, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QU24-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU24" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU24" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 195, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 362 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 350, "end_pos": 352 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QU73-1", "uniprot_ac": "A0A5G2QU73", "uniprot_id": "A0A5G2QU73_PIG", "mass": { "chemical_mass": 18897.0, "monoisotopic_mass": 18897.0 }, "refseq": { "ac": "XP_020926282", "name": "antibacterial peptide PMAP-37 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926282" }, "gene_names": [ { "name": "LOC110255221", "type": "recommended", "evidence": [ { "id": "A0A5G2QU73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73" } ] }, { "name": "PMAP37", "type": "synonym", "evidence": [ { "id": "XP_020926282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926282" } ] } ], "protein_names": [ { "name": "Myeloid antibacterial peptide 37", "type": "synonym", "evidence": [ { "id": "XP_020926282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926282" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A5G2QU73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73/entry#names_and_taxonomy" } ] }, { "name": "antibacterial peptide PMAP-37 precursor", "type": "synonym", "evidence": [ { "id": "XP_020926282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926282" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU73", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110255221", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73", "locus": {} } ], "crossref": [ { "id": "A0A5G2QU73", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU73", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000047135", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000047135", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110255221", "url": "https://www.ncbi.nlm.nih.gov/gene/110255221", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110255221", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255221", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QU73", "url": "https://www.orthodb.org/?gene=A0A5G2QU73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10206", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10206", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10206:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10206:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00666", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00666", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6803157", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6803157", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020926282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926282", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QU73", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QU73-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METQRASLCLGRWSLWLLLLALVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRRPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEIQSVGLLSRLRDFLSDRGRRLGEKIERIGQKIKDLSEFFQS", "length": 167, "header": "tr|A0A5G2QU73-1|A0A5G2QU73_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN=LOC110255221 PE=3 SV=1 CANONICAL=A0A5G2QU73-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QU73-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73/entry#A0A5G2QU73-1", "sequence": { "sequence": "METQRASLCLGRWSLWLLLLALVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRRPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEIQSVGLLSRLRDFLSDRGRRLGEKIERIGQKIKDLSEFFQS", "length": 167, "header": "tr|A0A5G2QU73-1|A0A5G2QU73_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN=LOC110255221 PE=3 SV=1 CANONICAL=A0A5G2QU73-1" }, "locus": { "chromosome": "13", "start_pos": 31013102, "end_pos": 31011192, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085984.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085984.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068398.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068398.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU73", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110255221", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255221", "resource": "KEGG Pathway" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-6803157", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6803157", "resource": "Reactome", "description": "Antimicrobial peptides" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU73", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU73", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73" } ], "pmid": "" }, { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU73", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU73", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73" } ], "pmid": "" }, { "name": "antimicrobial humoral immune response mediated by antimicrobial peptide", "id": "GO:0061844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061844", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU73", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipopolysaccharide binding", "id": "GO:0001530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001530", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU73", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QU73-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 167, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QU73-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU73" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QU83-1", "uniprot_ac": "A0A5G2QU83", "uniprot_id": "A0A5G2QU83_PIG", "mass": { "chemical_mass": 34878.0, "monoisotopic_mass": 34878.0 }, "refseq": { "ac": "XP_020938034", "name": "olfactory receptor 4C13-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938034" }, "gene_names": [ { "name": "LOC110259080", "type": "recommended", "evidence": [ { "id": "A0A5G2QU83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83" } ] }, { "name": "LOC110259080", "type": "synonym", "evidence": [ { "id": "XP_020938034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938034" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QU83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4C13-like", "type": "synonym", "evidence": [ { "id": "XP_020938034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938034" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259080", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83", "locus": {} } ], "crossref": [ { "id": "A0A5G2QU83", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU83", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110259080", "url": "https://www.ncbi.nlm.nih.gov/gene/110259080", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110259080", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259080", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QU83", "url": "https://www.orthodb.org/?gene=A0A5G2QU83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020938034", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938034", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QU83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QU83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENRNNVTEFVLLGLTQNPKMQKVIFVVFLIIYIISMGGNVLTMVTITTSPLLKSPMYFFLAHLSFIDACYSCVTTPKLIVDSLHEKKTSPFNECMTQIFGEHFFAGADIIVLTSMAYDRYVAICKPLHYTTIMNWQLCWLLVGVSWVGGFLHGFIQILFIFRLPFCGPNVINHFMCDLNPLLDLACTDTHTLGLFVAANSGFICLLIFLLLIGSYTVILHSLRTQSFEAKQKALSTCVSHITVIVLFFVPSIFVYMRPSANLPVDKAVAVFYSMIAPMLNPLIYTLRNSEMKNAIRKFCSRKVISSDQ", "length": 309, "header": "tr|A0A5G2QU83-1|A0A5G2QU83_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259080 PE=3 SV=1 CANONICAL=A0A5G2QU83-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QU83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83/entry#A0A5G2QU83-1", "sequence": { "sequence": "MENRNNVTEFVLLGLTQNPKMQKVIFVVFLIIYIISMGGNVLTMVTITTSPLLKSPMYFFLAHLSFIDACYSCVTTPKLIVDSLHEKKTSPFNECMTQIFGEHFFAGADIIVLTSMAYDRYVAICKPLHYTTIMNWQLCWLLVGVSWVGGFLHGFIQILFIFRLPFCGPNVINHFMCDLNPLLDLACTDTHTLGLFVAANSGFICLLIFLLLIGSYTVILHSLRTQSFEAKQKALSTCVSHITVIVLFFVPSIFVYMRPSANLPVDKAVAVFYSMIAPMLNPLIYTLRNSEMKNAIRKFCSRKVISSDQ", "length": 309, "header": "tr|A0A5G2QU83-1|A0A5G2QU83_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259080 PE=3 SV=1 CANONICAL=A0A5G2QU83-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 200728, "end_pos": 199802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084688.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084688.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068496.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068496.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110259080", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259080", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QU83-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QU83-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU83" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QU83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU83" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QU99-1", "uniprot_ac": "A0A5G2QU99", "uniprot_id": "A0A5G2QU99_PIG", "mass": { "chemical_mass": 35935.0, "monoisotopic_mass": 35935.0 }, "refseq": { "ac": "XP_003123441", "name": "olfactory receptor 7A17-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123441" }, "gene_names": [ { "name": "LOC100521773", "type": "recommended", "evidence": [ { "id": "A0A5G2QU99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99" } ] }, { "name": "LOC100521773", "type": "synonym", "evidence": [ { "id": "XP_003123441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123441" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QU99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7A17-like", "type": "synonym", "evidence": [ { "id": "XP_003123441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123441" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU99", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU99", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100521773", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99", "locus": {} } ], "crossref": [ { "id": "A0A5G2QU99", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU99", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521773", "url": "https://www.ncbi.nlm.nih.gov/gene/100521773", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521773", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521773", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MEPCNDT", "url": "https://omabrowser.org/oma/group/MEPCNDT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QU99", "url": "https://www.orthodb.org/?gene=A0A5G2QU99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003123441", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123441", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QU99", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QU99-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPCNDTQISEFLLLGFAEEPEWQLLIFGLFLYMYLITVFGNLLIILVVTSDCQLHKPMFFFLSNLSFVDICFISTTIPKMLWNIQTQSKVITYEDCITQIYFFILSAVLDIFLLTVMAYDRFVAICHPLHYTVIMNPQLCRLLVLVSWIICILNSLLQCLMTLQLSFRGSVEIPHFFCDLSQIIQLSCSDTFLNNMVMYFTVGLLGGGPLAGILYSYSKIVSCIRRISSAQGKYKAFSTCASHLLVVSLFFCTSIGVYFSAAATHGSHASAVASVMYTVVTPLLNPFIYSLRNKDIKGALKRFFAMESLKRKLILGL", "length": 318, "header": "tr|A0A5G2QU99-1|A0A5G2QU99_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100521773 PE=3 SV=1 CANONICAL=A0A5G2QU99-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QU99-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99/entry#A0A5G2QU99-1", "sequence": { "sequence": "MEPCNDTQISEFLLLGFAEEPEWQLLIFGLFLYMYLITVFGNLLIILVVTSDCQLHKPMFFFLSNLSFVDICFISTTIPKMLWNIQTQSKVITYEDCITQIYFFILSAVLDIFLLTVMAYDRFVAICHPLHYTVIMNPQLCRLLVLVSWIICILNSLLQCLMTLQLSFRGSVEIPHFFCDLSQIIQLSCSDTFLNNMVMYFTVGLLGGGPLAGILYSYSKIVSCIRRISSAQGKYKAFSTCASHLLVVSLFFCTSIGVYFSAAATHGSHASAVASVMYTVVTPLLNPFIYSLRNKDIKGALKRFFAMESLKRKLILGL", "length": 318, "header": "tr|A0A5G2QU99-1|A0A5G2QU99_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100521773 PE=3 SV=1 CANONICAL=A0A5G2QU99-1" }, "locus": { "chromosome": "2", "start_pos": 63534604, "end_pos": 63533651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085027.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085027.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067729.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067729.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU99", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521773", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521773", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU99", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU99", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU99", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU99", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QU99-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 318, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QU99-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QU99" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QU99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU99" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QUA8-1", "uniprot_ac": "A0A5G2QUA8", "uniprot_id": "A0A5G2QUA8_PIG", "mass": { "chemical_mass": 44888.0, "monoisotopic_mass": 44888.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QUA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QUA8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUA8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045241", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045241", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QUA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQVEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKHWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRMKNGSPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHVVNFITTTTSISQFRCISNFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2QUA8-1|A0A5G2QUA8_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QUA8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA8/entry#A0A5G2QUA8-1", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQVEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKHWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRMKNGSPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHVVNFITTTTSISQFRCISNFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2QUA8-1|A0A5G2QUA8_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QUA8-1" }, "locus": { "chromosome": "Y", "start_pos": 21445652, "end_pos": 21444023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082910.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082910.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068521.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068521.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QUA8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QUA8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUA8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QUA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA8" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2QUC5-1", "uniprot_ac": "A0A5G2QUC5", "uniprot_id": "A0A5G2QUC5_PIG", "mass": { "chemical_mass": 35586.0, "monoisotopic_mass": 35586.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5", "locus": {} } ], "crossref": [ { "id": "A0A5G2QUC5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUC5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15955", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15955", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QUC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFQRNDTVFMPLVLRLTGIPGLEPVQAWIGIPFCAMYVLALFGNSLLLVAIKSERSLHEPMCLFLAMLGATDVMLSTCILPKMLGIFWFHSPEIDFDACLFQMWLIHSFQCIESGVLLAMALDRYVAICDPLRHAAIFTPQLVTRIGVAVTLRAALLVAPCLILIKCRLKHYRTTVVSHSYCEHMAVVKLAAEDVRINKIYGLFVAFIVLGFDIIFITLSYIRIFVTVFSLPQREARLKAFNTCVAHICVFLEFYLLAFFSFFTHRFGFHIPPYVHILLSNLYLLTKQIRDRVSRIFYCEHVRIVGSLSKY", "length": 311, "header": "tr|A0A5G2QUC5-1|A0A5G2QUC5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QUC5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5/entry#A0A5G2QUC5-1", "sequence": { "sequence": "MFQRNDTVFMPLVLRLTGIPGLEPVQAWIGIPFCAMYVLALFGNSLLLVAIKSERSLHEPMCLFLAMLGATDVMLSTCILPKMLGIFWFHSPEIDFDACLFQMWLIHSFQCIESGVLLAMALDRYVAICDPLRHAAIFTPQLVTRIGVAVTLRAALLVAPCLILIKCRLKHYRTTVVSHSYCEHMAVVKLAAEDVRINKIYGLFVAFIVLGFDIIFITLSYIRIFVTVFSLPQREARLKAFNTCVAHICVFLEFYLLAFFSFFTHRFGFHIPPYVHILLSNLYLLTKQIRDRVSRIFYCEHVRIVGSLSKY", "length": 311, "header": "tr|A0A5G2QUC5-1|A0A5G2QUC5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QUC5-1" }, "locus": { "chromosome": "AEMK02000658.1", "start_pos": 62036, "end_pos": 60507, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087226.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087226.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067754.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067754.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QUC5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QUC5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUC5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUC5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 298, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "uniprot_ac": "A0A5G2QUE5", "uniprot_id": "A0A5G2QUE5_PIG", "mass": { "chemical_mass": 35093.0, "monoisotopic_mass": 35093.0 }, "refseq": { "ac": "XP_003122195", "name": "olfactory receptor 1J4-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122195" }, "gene_names": [ { "name": "LOC100524011", "type": "recommended", "evidence": [ { "id": "A0A5G2QUE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5" } ] }, { "name": "LOC100524011", "type": "synonym", "evidence": [ { "id": "XP_003122195", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122195" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QUE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1J4-like", "type": "synonym", "evidence": [ { "id": "XP_003122195", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122195" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100524011", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5", "locus": {} } ], "crossref": [ { "id": "A0A5G2QUE5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUE5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000047130", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000047130", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524011", "url": "https://www.ncbi.nlm.nih.gov/gene/100524011", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524011", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524011", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QUE5", "url": "https://www.orthodb.org/?gene=A0A5G2QUE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003122195", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122195", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QUE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313, "header": "tr|A0A5G2QUE5-1|A0A5G2QUE5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524011 PE=3 SV=1 CANONICAL=A0A5G2QUE5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5/entry#A0A5G2QUE5-1", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313, "header": "tr|A0A5G2QUE5-1|A0A5G2QUE5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524011 PE=3 SV=1 CANONICAL=A0A5G2QUE5-1" }, "locus": { "chromosome": "1", "start_pos": 262690628, "end_pos": 262689690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079451.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079451.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068453.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068453.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524011", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524011", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "A0A5G2QUE5", "url": "https://omabrowser.org/oma/group/A0A5G2QUE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QUE5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QUE5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUE5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QUE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QUK6-1", "uniprot_ac": "A0A5G2QUK6", "uniprot_id": "A0A5G2QUK6_PIG", "mass": { "chemical_mass": 76224.0, "monoisotopic_mass": 76224.0 }, "refseq": {}, "gene_names": [ { "name": "AACS", "type": "recommended", "evidence": [ { "id": "A0A5G2QUK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6" } ] } ], "protein_names": [ { "name": "Acetoacetyl-CoA synthetase", "type": "recommended", "evidence": [ { "id": "A0A5G2QUK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6/entry#names_and_taxonomy" } ] }, { "name": "6.2.1.16", "type": "synonym", "evidence": [ { "id": "A0A5G2QUK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Converts acetoacetate to acetoacetyl-CoA in the cytosol.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6#function" }, { "database": "UniProtKB", "id": "RU367019", "url": "https://www.uniprot.org/uniprotkb/RU367019#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AACS", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6", "locus": { "chromosome": "14", "start_pos": 28109869, "end_pos": 28169253, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009755", "url": "https://www.ensembl.org/id/ENSSSCG00000009755" } ] } } ], "crossref": [ { "id": "A0A5G2QUK6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009755", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009755", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05943", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05943", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR42921", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42921", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42921:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42921:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-77111", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77111", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "16117", "url": "https://www.rhea-db.org/rhea/16117", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QUK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKDTRAGQEEILECQVMWEPDSKKNTQMDSFREAAGAVCGLALENYDDLYHWSVESYSDFWAEFWKFSRIVFSRMYDEVVDTSKGISDVPEWFKGSRLNYAENLLQHKENDRVALYVAREGKEEILKVTFEELRQQVALFAAAMRKMGVKKGDRVVGYLPNSVHAVEAMLAAASIGAIWSSTSPDFGVNVSQGPCRCPGYGVLDRFSQIQPKLIFSVEAVMYNGKEHGHMDKLQQVVKGLPDLEKVVVIPYISSREKIDISKMPNSVFLEDFLATGKGEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHILHGNMTSSDIIFYYTTVGWMMWNWVVSALATGAAVVLYDGSPLVPTPNVLWDLVDRIGITILGTGAKWLSVLEEKNMKPAETHSLQTLHTILSTGSPLKAQSYEYVYRCIKSSVLLGSISGGTDIISCFMGQNPCVPVYKGEIQARNLGMAVEAWNEEGKAVWGERGELVCTKPLPCQPTHFWNDENGSKYRKAYFSKFPGVWAHGDYCRINPKTGGIIMLGRSDGTLNPNGVRFGSSEIYNIVEAFEEVMDSLCVPQFNKDGEERVILFLKMASGHTFQPDLVKSIRNAIRLGLSARHVPSLILETKDIPYTLNGKKVEVAVKQIIAGKAVEHRGAFSNPETLDLYRDIPELQDF", "length": 683, "header": "tr|A0A5G2QUK6-1|A0A5G2QUK6_PIG Isoform 1 of Acetoacetyl-CoA synthetase OS=Sus scrofa OX=9823 GN=AACS PE=3 SV=2 CANONICAL=A0A5G2QUK6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6/entry#A0A5G2QUK6-1", "sequence": { "sequence": "MSKDTRAGQEEILECQVMWEPDSKKNTQMDSFREAAGAVCGLALENYDDLYHWSVESYSDFWAEFWKFSRIVFSRMYDEVVDTSKGISDVPEWFKGSRLNYAENLLQHKENDRVALYVAREGKEEILKVTFEELRQQVALFAAAMRKMGVKKGDRVVGYLPNSVHAVEAMLAAASIGAIWSSTSPDFGVNVSQGPCRCPGYGVLDRFSQIQPKLIFSVEAVMYNGKEHGHMDKLQQVVKGLPDLEKVVVIPYISSREKIDISKMPNSVFLEDFLATGKGEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHILHGNMTSSDIIFYYTTVGWMMWNWVVSALATGAAVVLYDGSPLVPTPNVLWDLVDRIGITILGTGAKWLSVLEEKNMKPAETHSLQTLHTILSTGSPLKAQSYEYVYRCIKSSVLLGSISGGTDIISCFMGQNPCVPVYKGEIQARNLGMAVEAWNEEGKAVWGERGELVCTKPLPCQPTHFWNDENGSKYRKAYFSKFPGVWAHGDYCRINPKTGGIIMLGRSDGTLNPNGVRFGSSEIYNIVEAFEEVMDSLCVPQFNKDGEERVILFLKMASGHTFQPDLVKSIRNAIRLGLSARHVPSLILETKDIPYTLNGKKVEVAVKQIIAGKAVEHRGAFSNPETLDLYRDIPELQDF", "length": 683, "header": "tr|A0A5G2QUK6-1|A0A5G2QUK6_PIG Isoform 1 of Acetoacetyl-CoA synthetase OS=Sus scrofa OX=9823 GN=AACS PE=3 SV=2 CANONICAL=A0A5G2QUK6-1" }, "locus": { "chromosome": "14", "start_pos": 28169081, "end_pos": 28110954, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079199.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079199.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068631.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068631.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-77111", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77111", "resource": "Reactome", "description": "Synthesis of Ketone Bodies" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6" } ], "pmid": "" }, { "name": "acetoacetate-CoA ligase activity", "id": "GO:0030729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030729", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6" } ], "pmid": "" }, { "name": "positive regulation of insulin secretion", "id": "GO:0032024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032024", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16117", "name": "", "equation": "acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16117", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16117" } ] }, { "id": "R-SSC-5694494", "name": "AACS ligates CoA-SH to ACA, forming ACA-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29666" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5694494", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5694494" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29666", "participant_name": "ACA [cytosol]", "crossref": [ { "id": "13705", "database": "ChEBI", "url": "" }, { "id": "ZINC000000895089", "database": "ZINC", "url": "" }, { "id": "C00164", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QUK6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 683, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QUK6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUK6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QUK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6" }, { "id": "PF00501", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AMP-dependent synthetase/ligase", "eco_id": "ECO_0000259", "start_pos": 110, "end_pos": 501, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QUK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK6" }, { "id": "PF16177", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Acetyl-coenzyme A synthetase N-terminal", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 104, "start_aa": "Tyr", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 514, "end_pos": 516 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QUK8-1", "uniprot_ac": "A0A5G2QUK8", "uniprot_id": "A0A5G2QUK8_PIG", "mass": { "chemical_mass": 35108.0, "monoisotopic_mass": 35108.0 }, "refseq": { "ac": "XP_013849745", "name": "olfactory receptor 5B3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849745" }, "gene_names": [ { "name": "LOC106509346", "type": "recommended", "evidence": [ { "id": "A0A5G2QUK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8" } ] }, { "name": "LOC106509346", "type": "synonym", "evidence": [ { "id": "XP_013849745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849745" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QUK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5B3-like", "type": "synonym", "evidence": [ { "id": "XP_013849745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849745" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC106509346", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QUK8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "106509346", "url": "https://www.ncbi.nlm.nih.gov/gene/106509346", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:106509346", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106509346", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VHIRDTF", "url": "https://omabrowser.org/oma/group/VHIRDTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QUK8", "url": "https://www.orthodb.org/?gene=A0A5G2QUK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013849745", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849745", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QUK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENYTEVTEFILLGLTNAPELQVPLFIMFTLIYLINVVGNLGMIVLILLDPRLHIPMYFFLSHLSLVDFCYSTAVTPKVMAGFLIGDKVISYNACAAQMFFFVALGTVENFLLASMAYDRFAAVCKPLHYTTTMMTGVCAWLAIGSYVYGFLNASIHVRDTFSLSFCRSNLVHHFFCDIPAVMALSCSDRHISELILVVVASFNIFFALLVILVSYLFIFITTLKMHSIEGYLKALSTCASHLTAVSIFYGTVIFMYLQASPSHSTDTDKIASVFYGMVIPTLNPLVYSLRNKEVKNAFKKVVEKAKLSIGFTF", "length": 314, "header": "tr|A0A5G2QUK8-1|A0A5G2QUK8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC106509346 PE=3 SV=1 CANONICAL=A0A5G2QUK8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8/entry#A0A5G2QUK8-1", "sequence": { "sequence": "MENYTEVTEFILLGLTNAPELQVPLFIMFTLIYLINVVGNLGMIVLILLDPRLHIPMYFFLSHLSLVDFCYSTAVTPKVMAGFLIGDKVISYNACAAQMFFFVALGTVENFLLASMAYDRFAAVCKPLHYTTTMMTGVCAWLAIGSYVYGFLNASIHVRDTFSLSFCRSNLVHHFFCDIPAVMALSCSDRHISELILVVVASFNIFFALLVILVSYLFIFITTLKMHSIEGYLKALSTCASHLTAVSIFYGTVIFMYLQASPSHSTDTDKIASVFYGMVIPTLNPLVYSLRNKEVKNAFKKVVEKAKLSIGFTF", "length": 314, "header": "tr|A0A5G2QUK8-1|A0A5G2QUK8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC106509346 PE=3 SV=1 CANONICAL=A0A5G2QUK8-1" }, "locus": { "chromosome": "2", "start_pos": 12654721, "end_pos": 12653780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070980.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070980.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068518.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068518.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 76, "start_aa": "Thr", "end_pos": 76, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr76", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:106509346", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106509346", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QUK8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QUK8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUK8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QUK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUK8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 76 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QUN5-1", "uniprot_ac": "A0A5G2QUN5", "uniprot_id": "A0A5G2QUN5_PIG", "mass": { "chemical_mass": 35744.0, "monoisotopic_mass": 35744.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100525329", "type": "recommended", "evidence": [ { "id": "A0A5G2QUN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QUN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100525329", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5", "locus": {} } ], "crossref": [ { "id": "A0A5G2QUN5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUN5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QUN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGQNYSTVSEFILIGFSNFPQQLLPTFFLLYLLMYLFTLLGNLLIMTTIWREHSLHTPMYLFLCALSTSEILFTVAITPRMLVDMLSVYRSITFVACASQMFFSFTFGYTHSFLLMILGYDRYVAICHPLHYNMLMSTRDCARLVSWSWAGGSAVGMMVTLIVFNLTFCGSNVIHHFFCHVFSLLKLTCGNETSSLTIVVILVCVTALMGCLFLIVLSYVFIVAAILRIPSAEGRHKTFSTCVSHLTIVIVHYGFASIIYLKPKGPRSMDSNTLMTTTYTVFTPFLSPIIFSLRNKELKNAIKRSFQRAFCPLSS", "length": 316, "header": "tr|A0A5G2QUN5-1|A0A5G2QUN5_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100525329 PE=3 SV=2 CANONICAL=A0A5G2QUN5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5/entry#A0A5G2QUN5-1", "sequence": { "sequence": "MSGQNYSTVSEFILIGFSNFPQQLLPTFFLLYLLMYLFTLLGNLLIMTTIWREHSLHTPMYLFLCALSTSEILFTVAITPRMLVDMLSVYRSITFVACASQMFFSFTFGYTHSFLLMILGYDRYVAICHPLHYNMLMSTRDCARLVSWSWAGGSAVGMMVTLIVFNLTFCGSNVIHHFFCHVFSLLKLTCGNETSSLTIVVILVCVTALMGCLFLIVLSYVFIVAAILRIPSAEGRHKTFSTCVSHLTIVIVHYGFASIIYLKPKGPRSMDSNTLMTTTYTVFTPFLSPIIFSLRNKELKNAIKRSFQRAFCPLSS", "length": 316, "header": "tr|A0A5G2QUN5-1|A0A5G2QUN5_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100525329 PE=3 SV=2 CANONICAL=A0A5G2QUN5-1" }, "locus": { "chromosome": "2", "start_pos": 61648411, "end_pos": 61647464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091162.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091162.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065677.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065677.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QUN5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 316, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QUN5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUN5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QUN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUN5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 292, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 79 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QUP1-1", "uniprot_ac": "A0A5G2QUP1", "uniprot_id": "A0A5G2QUP1_PIG", "mass": { "chemical_mass": 35159.0, "monoisotopic_mass": 35159.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100514797", "type": "recommended", "evidence": [ { "id": "A0A5G2QUP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QUP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100514797", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1", "locus": {} } ], "crossref": [ { "id": "A0A5G2QUP1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100514797", "url": "https://www.ncbi.nlm.nih.gov/gene/100514797", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514797", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514797", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QUP1", "url": "https://www.orthodb.org/?gene=A0A5G2QUP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013845622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845622", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QUP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METKNATELTEFVLTGLKYQSEWQIPLFLLFLIIYLITLIGNLGLIALICNDPHLHSPMYLFLGNLAFVDTWLSSTVTPNMLVNFFSKSKMISLSECKIQFFSFAICATTECFLLATMAYDRYVAICKPLLYPVIMTNRLCIQLLILSFLGGLSHAIIHNVFLLRLTFCNSIIIHHFYCDIIPLFKISCTDPSINYMMVLIFAGIIQIFTISVVLASYTLVLFTILKKKSMQGTRKTFSTCGAHLLSVSLYYGPLLFMYVLPGSAEENDQDMMDSLFYAVIIPFLNPIIYSLRNKKVIDSITKMLKRNV", "length": 309, "header": "tr|A0A5G2QUP1-1|A0A5G2QUP1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100514797 PE=3 SV=1 CANONICAL=A0A5G2QUP1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1/entry#A0A5G2QUP1-1", "sequence": { "sequence": "METKNATELTEFVLTGLKYQSEWQIPLFLLFLIIYLITLIGNLGLIALICNDPHLHSPMYLFLGNLAFVDTWLSSTVTPNMLVNFFSKSKMISLSECKIQFFSFAICATTECFLLATMAYDRYVAICKPLLYPVIMTNRLCIQLLILSFLGGLSHAIIHNVFLLRLTFCNSIIIHHFYCDIIPLFKISCTDPSINYMMVLIFAGIIQIFTISVVLASYTLVLFTILKKKSMQGTRKTFSTCGAHLLSVSLYYGPLLFMYVLPGSAEENDQDMMDSLFYAVIIPFLNPIIYSLRNKKVIDSITKMLKRNV", "length": 309, "header": "tr|A0A5G2QUP1-1|A0A5G2QUP1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100514797 PE=3 SV=1 CANONICAL=A0A5G2QUP1-1" }, "locus": { "chromosome": "13", "start_pos": 161963553, "end_pos": 161962627, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088400.1", "url": "https://www.ensembl.org/id/ENSSSCT00000088400.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065682.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065682.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514797", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514797", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QUP1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QUP1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUP1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QUP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUP1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QUQ3-1", "uniprot_ac": "A0A5G2QUQ3", "uniprot_id": "A0A5G2QUQ3_PIG", "mass": { "chemical_mass": 85173.0, "monoisotopic_mass": 85173.0 }, "refseq": {}, "gene_names": [ { "name": "EZH1", "type": "recommended", "evidence": [ { "id": "A0A5G2QUQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" } ] } ], "protein_names": [ { "name": "[histone H3]-lysine(27) N-trimethyltransferase", "type": "recommended", "evidence": [ { "id": "A0A5G2QUQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.356", "type": "synonym", "evidence": [ { "id": "A0A5G2QUQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EZH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3", "locus": { "chromosome": "12", "start_pos": 20141749, "end_pos": 20115297, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017382", "url": "https://www.ensembl.org/id/ENSSSCG00000017382" } ] } } ], "crossref": [ { "id": "A0A5G2QUQ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017382", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017382", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19217", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19217", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045318", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045318", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45747", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45747", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45747:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45747:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11616", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11616", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18118", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18118", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18264", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18264", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21358", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21358", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-212300", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "60292", "url": "https://www.rhea-db.org/rhea/60292", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QUQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8X2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1G9", "url": "https://www.uniprot.org/uniprotkb/F1S1G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1G9-1", "url": "https://www.uniprot.org/uniprotkb/F1S1G9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIQNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEWKKLRVQPVQLMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEDGHNDNSDGKQDDSKEDLPVTRKRKHAIEGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHVVSASCSNTSASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL", "length": 746, "header": "tr|A0A5G2QUQ3-1|A0A5G2QUQ3_PIG Isoform 1 of [histone H3]-lysine(27) N-trimethyltransferase OS=Sus scrofa OX=9823 GN=EZH1 PE=4 SV=1 CANONICAL=A0A5G2QUQ3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3/entry#A0A5G2QUQ3-1", "sequence": { "sequence": "MDIQNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEWKKLRVQPVQLMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEDGHNDNSDGKQDDSKEDLPVTRKRKHAIEGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHVVSASCSNTSASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL", "length": 746, "header": "tr|A0A5G2QUQ3-1|A0A5G2QUQ3_PIG Isoform 1 of [histone H3]-lysine(27) N-trimethyltransferase OS=Sus scrofa OX=9823 GN=EZH1 PE=4 SV=1 CANONICAL=A0A5G2QUQ3-1" }, "locus": { "chromosome": "12", "start_pos": 20139416, "end_pos": 20118356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085050.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085050.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067879.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067879.1" } ] } }, { "isoform_ac": "A0A5G2R8X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3/entry#A0A5G2R8X2-1", "sequence": { "sequence": "ALYVANFAKVQEKTQILNEEWKKLRVQPVQLMKPVSGHPFLKKVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEDGHNDNSDGKQDDSKEDLPVTRKRKHAIEGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHVVSASCSNTSASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL", "length": 667, "header": "tr|A0A5G2R8X2-1|A0A5G2R8X2_PIG Computationally mapped isoform of [histone H3]-lysine(27) N-trimethyltransferase OS=Sus scrofa OX=9823 GN=EZH1 PE=4 SV=2 CANONICAL=A0A5G2QUQ3-1" }, "locus": { "chromosome": "12", "start_pos": 20139416, "end_pos": 20118863, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072319.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072319.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072774.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072774.2" } ] } }, { "isoform_ac": "F1S1G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3/entry#F1S1G9-1", "sequence": { "sequence": "MDIQNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEWKKLRVQPVQLMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELVDALNQYSDEEEDGHNDNSDGKQDDSKEDLPVTRKRKDMLLKGNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNVYKRKNKEIKIEPEPCGTDCFLLLEGAKEYAMLHNPRSKCSGRRRRRHHVVSASCSNTSASAVAETKEGDSDRDTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLPTDELMNPSQKKKRKHRIWHCRELCLSCVFFPFPDNSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL", "length": 751, "header": "tr|F1S1G9-1|A0A5G2QUQ3_PIG Computationally mapped isoform of [histone H3]-lysine(27) N-trimethyltransferase OS=Sus scrofa OX=9823 GN=EZH1 PE=4 SV=4 CANONICAL=A0A5G2QUQ3-1" }, "locus": { "chromosome": "12", "start_pos": 20139416, "end_pos": 20118356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018921.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018921.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018416.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018416.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1G9", "url": "https://www.uniprot.org/uniprotkb/F1S1G9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-212300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212300", "resource": "Reactome", "description": "PRC2 methylates histones and DNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ESC/E(Z) complex", "id": "GO:0035098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035098", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "histone H3K27 trimethyltransferase activity", "id": "GO:0140951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140951", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" } ], "pmid": "" }, { "name": "histone H3K27 methyltransferase activity", "id": "GO:0046976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046976", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60292", "name": "", "equation": "L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60292", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60292" } ] }, { "id": "R-SSC-212252", "name": "Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-212252", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212252" } ] }, { "id": "R-SSC-212263", "name": "PRC2 trimethylates histone H3 at lysine-27", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-212263", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212263" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QUQ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 746, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QUQ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUQ3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QUQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" }, { "id": "PS51633", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51633" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CXC", "eco_id": "ECO_0000259", "start_pos": 503, "end_pos": 605, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QUQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUQ3" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 612, "end_pos": 727, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 373, "end_pos": 375 }, { "start_pos": 512, "end_pos": 514 }, { "start_pos": 603, "end_pos": 605 }, { "start_pos": 688, "end_pos": 690 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QUS0-1", "uniprot_ac": "A0A5G2QUS0", "uniprot_id": "A0A5G2QUS0_PIG", "mass": { "chemical_mass": 41042.0, "monoisotopic_mass": 41042.0 }, "refseq": { "ac": "XP_003358456", "name": "receptor-transporting protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358456" }, "gene_names": [ { "name": "RTP3", "type": "recommended", "evidence": [ { "id": "A0A5G2QUS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0" } ] }, { "name": "RTP3", "type": "synonym", "evidence": [ { "id": "XP_003358456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358456" } ] } ], "protein_names": [ { "name": "Receptor transporter protein 3", "type": "synonym", "evidence": [ { "id": "A0A5G2QUS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0/entry#names_and_taxonomy" } ] }, { "name": "receptor-transporting protein 3", "type": "synonym", "evidence": [ { "id": "XP_003358456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358456" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RTP3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0", "locus": {} } ], "crossref": [ { "id": "A0A5G2QUS0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045673", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045673", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100622765", "url": "https://www.ncbi.nlm.nih.gov/gene/100622765", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100622765", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622765", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QUS0", "url": "https://www.orthodb.org/?gene=A0A5G2QUS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14402", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14402", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14402:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14402:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13695", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13695", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003358456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358456", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QUS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZH6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMGQNTEVWKQVFQELIQEVKPWHMWTLILDRSLLPNILKPGWTQYQQWAFARFQCSSCSQNWASSQVQVLFHMHWSEGESRGQVKMRIFSQRCKKCSQSSFEVPKFTEENISRILNNLVLRILKKCYGEGFKLVEIPIIKEVSLEGPHDSDNCEACLQGFCIQSGLGLATQAPMSPSLPTISSPPVEIAIQMPSPTRSSTTEDAVKKKKVIPRPWFPEATQAESLPTSWSPRADTNSQNQRADISSQSPRADTNSSQSQRVDISSQNLRAKTNSQSPRRKTNSQSPRAKTKSQSPRTDTSSQRWRANTYLQVERRVQDSLSREVYYSHTAQTFRSRNLGCCCCLILIIIVIVIVIKITI", "length": 361, "header": "tr|A0A5G2QUS0-1|A0A5G2QUS0_PIG Isoform 1 of Receptor transporter protein 3 OS=Sus scrofa OX=9823 GN=RTP3 PE=4 SV=1 CANONICAL=A0A5G2QUS0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0/entry#A0A5G2QUS0-1", "sequence": { "sequence": "MAMGQNTEVWKQVFQELIQEVKPWHMWTLILDRSLLPNILKPGWTQYQQWAFARFQCSSCSQNWASSQVQVLFHMHWSEGESRGQVKMRIFSQRCKKCSQSSFEVPKFTEENISRILNNLVLRILKKCYGEGFKLVEIPIIKEVSLEGPHDSDNCEACLQGFCIQSGLGLATQAPMSPSLPTISSPPVEIAIQMPSPTRSSTTEDAVKKKKVIPRPWFPEATQAESLPTSWSPRADTNSQNQRADISSQSPRADTNSSQSQRVDISSQNLRAKTNSQSPRRKTNSQSPRAKTKSQSPRTDTSSQRWRANTYLQVERRVQDSLSREVYYSHTAQTFRSRNLGCCCCLILIIIVIVIVIKITI", "length": 361, "header": "tr|A0A5G2QUS0-1|A0A5G2QUS0_PIG Isoform 1 of Receptor transporter protein 3 OS=Sus scrofa OX=9823 GN=RTP3 PE=4 SV=1 CANONICAL=A0A5G2QUS0-1" }, "locus": { "chromosome": "13", "start_pos": 29475518, "end_pos": 29472995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067046.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067046.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061916.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061916.1" } ] } }, { "isoform_ac": "A0A5G2QZH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0/entry#A0A5G2QZH6-1", "sequence": { "sequence": "MAMGQNTEVWKQVFQELIQEVKPWHMWTLILDRSLLPNILKPGWTQYQQWAFARFQCSSCSQNWASSQVQVLFHMHWSEGESRGQVKMRIFSQRCKKCSQSSFEVPKFTEENISRILNNLVLRILKKCYGEGFKLVEIPIIKEVSLEGPHDSDNCEACLQGFCIQSGLGLATQAPMSPSLPTISSPPVEIAIQMPSPTRSSTTEDAVKKKKDPVTRKFYMDPLTSVCGGICCLKR", "length": 235, "header": "tr|A0A5G2QZH6-1|A0A5G2QUS0_PIG Computationally mapped isoform of Receptor transporter protein 3 OS=Sus scrofa OX=9823 GN=RTP3 PE=4 SV=1 CANONICAL=A0A5G2QUS0-1" }, "locus": { "chromosome": "13", "start_pos": 29475995, "end_pos": 29472995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088277.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088277.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070291.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070291.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100622765", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622765", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0" } ], "pmid": "" }, { "name": "olfactory receptor binding", "id": "GO:0031849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031849", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0" } ], "pmid": "" }, { "name": "protein insertion into membrane", "id": "GO:0051205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051205", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0" } ], "pmid": "" }, { "name": "detection of chemical stimulus involved in sensory perception of bitter taste", "id": "GO:0001580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001580", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QUS0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 361, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QUS0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUS0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QUS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS0" }, { "id": "SM01328", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01328" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "3CxxC-type", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 161, "start_aa": "Trp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 256, "end_pos": 258 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QUS3-1", "uniprot_ac": "A0A5G2QUS3", "uniprot_id": "A0A5G2QUS3_PIG", "mass": { "chemical_mass": 34571.0, "monoisotopic_mass": 34571.0 }, "refseq": { "ac": "XP_003481775", "name": "olfactory receptor 8S1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481775" }, "gene_names": [ { "name": "LOC100737106", "type": "recommended", "evidence": [ { "id": "A0A5G2QUS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3" } ] }, { "name": "LOC100737106", "type": "synonym", "evidence": [ { "id": "XP_003481775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481775" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QUS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8S1-like", "type": "synonym", "evidence": [ { "id": "XP_003481775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481775" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100737106", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3", "locus": {} } ], "crossref": [ { "id": "A0A5G2QUS3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15229", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15229", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737106", "url": "https://www.ncbi.nlm.nih.gov/gene/100737106", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737106", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737106", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LTREICI", "url": "https://omabrowser.org/oma/group/LTREICI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QUS3", "url": "https://www.orthodb.org/?gene=A0A5G2QUS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003481775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481775", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QUS3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLRNHSTITEFILLGLSADPTVQTLLFVLFLVIYLLTMMGNLMMLLVIRADSHLHIPMYFFLTHLSFLDLCFSSVTVPKLLENLLSKKKNISKEGCLTQAFFMFDIGGTEIFLLSAMAFDRYAAICYPLLYAQVMSSQLCVNLVWVSWGLGFLDAVINIPLAVNLDFCEAHIIPHYSCELPSFFPLSCSDNSTNVTVLVGSTVLHGFGTFFLIFFSYIRIVSTILSISSTSGRSKAFSTCSSHLIAVSFFYGSAFLRYLMPTSGSPLELIFSIQYGVVTPLVNPLIYSLKNKEVKTALRRTLGKCAGSKL", "length": 311, "header": "tr|A0A5G2QUS3-1|A0A5G2QUS3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100737106 PE=3 SV=1 CANONICAL=A0A5G2QUS3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3/entry#A0A5G2QUS3-1", "sequence": { "sequence": "MVLRNHSTITEFILLGLSADPTVQTLLFVLFLVIYLLTMMGNLMMLLVIRADSHLHIPMYFFLTHLSFLDLCFSSVTVPKLLENLLSKKKNISKEGCLTQAFFMFDIGGTEIFLLSAMAFDRYAAICYPLLYAQVMSSQLCVNLVWVSWGLGFLDAVINIPLAVNLDFCEAHIIPHYSCELPSFFPLSCSDNSTNVTVLVGSTVLHGFGTFFLIFFSYIRIVSTILSISSTSGRSKAFSTCSSHLIAVSFFYGSAFLRYLMPTSGSPLELIFSIQYGVVTPLVNPLIYSLKNKEVKTALRRTLGKCAGSKL", "length": 311, "header": "tr|A0A5G2QUS3-1|A0A5G2QUS3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100737106 PE=3 SV=1 CANONICAL=A0A5G2QUS3-1" }, "locus": { "chromosome": "5", "start_pos": 79069833, "end_pos": 79068901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071306.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071306.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068583.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068583.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737106", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737106", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUS3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QUS3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QUS3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUS3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QUS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QUV1-1", "uniprot_ac": "A0A5G2QUV1", "uniprot_id": "A0A5G2QUV1_PIG", "mass": { "chemical_mass": 34551.0, "monoisotopic_mass": 34551.0 }, "refseq": {}, "gene_names": [ { "name": "OR5B3", "type": "recommended", "evidence": [ { "id": "A0A5G2QUV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QUV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUV1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUV1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OR5B3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1", "locus": { "chromosome": "2", "start_pos": 12708380, "end_pos": 12707442, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000048530", "url": "https://www.ensembl.org/id/ENSSSCG00000048530" } ] } } ], "crossref": [ { "id": "A0A5G2QUV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519009", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519009", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHTVDTF", "url": "https://omabrowser.org/oma/group/IHTVDTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QUV1", "url": "https://www.orthodb.org/?gene=A0A5G2QUV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QUV1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNSTEVTQFILLGLTDDPELQVPLFTTFILVYLITLIGNLGIIMLILLDSHLHTPMYFFLSNLSLVDICYSSAVTPIVMAGFIPGDKVISYSACAAQMFFFAAFATVENYLLASMAYDRYVAVCKPLHYTTTMTTGVCVCLATGSYVCGFLNASIHIGDTFTLSFCRSNMVHHFFCDVPAVMVLSCSDRHVSELVLVYVVSFNIFFALLIILISYLLIFITILKMPSSAGYQKALSTCASHFTAVSIFYGTIIFMYLQPSSSHSMDTDKIASVFYAMIIPMLNPVVYSLRNKEVKSAFMKVVLEAKLSLGL", "length": 312, "header": "tr|A0A5G2QUV1-1|A0A5G2QUV1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR5B3 PE=3 SV=1 CANONICAL=A0A5G2QUV1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1/entry#A0A5G2QUV1-1", "sequence": { "sequence": "MKNSTEVTQFILLGLTDDPELQVPLFTTFILVYLITLIGNLGIIMLILLDSHLHTPMYFFLSNLSLVDICYSSAVTPIVMAGFIPGDKVISYSACAAQMFFFAAFATVENYLLASMAYDRYVAVCKPLHYTTTMTTGVCVCLATGSYVCGFLNASIHIGDTFTLSFCRSNMVHHFFCDVPAVMVLSCSDRHVSELVLVYVVSFNIFFALLIILISYLLIFITILKMPSSAGYQKALSTCASHFTAVSIFYGTIIFMYLQPSSSHSMDTDKIASVFYAMIIPMLNPVVYSLRNKEVKSAFMKVVLEAKLSLGL", "length": 312, "header": "tr|A0A5G2QUV1-1|A0A5G2QUV1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR5B3 PE=3 SV=1 CANONICAL=A0A5G2QUV1-1" }, "locus": { "chromosome": "2", "start_pos": 12708377, "end_pos": 12707442, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067133.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067133.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068608.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068608.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUV1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519009", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519009", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8VFW5-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLMENNTDVTQFLLLGLTDDPGLQFPLFITFLLIYTITLVGNLGMILLIVLDSRLHTPMYFFLGNLSLVDFCYSSAVTPTVMTGLIGEKIISYNDCAAQMFFFVAFATVENYLLASMAYDRYAAVCKPLHYATTMTANVCICLCIGSYTCGFLNASIHIGDTFSLSFCRSNVVHHFFCDIPAVMVLSCSDRHVSELVLVYVVSFNIFFALSVIWISYIFIFITICKMHSSSGYRKAISTCASHFIAVSIFYGTIIFMYLQPSSSHSMDTDKIASVFYTMIIPMLNPLVYSMRNKEVKSAFTKVLQVAK", "length": 309 }, "evidence": [ { "id": "A0A5G2QUV1", "url": "https://omabrowser.org/oma/group/A0A5G2QUV1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUV1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUV1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUV1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUV1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUV1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUV1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QUV1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QUV1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QUV1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QUV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QUZ5-1", "uniprot_ac": "A0A5G2QUZ5", "uniprot_id": "A0A5G2QUZ5_PIG", "mass": { "chemical_mass": 35038.0, "monoisotopic_mass": 35038.0 }, "refseq": { "ac": "XP_013845748", "name": "olfactory receptor 7G1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845748" }, "gene_names": [ { "name": "LOC100737921", "type": "recommended", "evidence": [ { "id": "A0A5G2QUZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5" } ] }, { "name": "LOC100514214", "type": "synonym", "evidence": [ { "id": "A0A5G2QUZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5" } ] }, { "name": "LOC100737921", "type": "synonym", "evidence": [ { "id": "XP_013845748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845748" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QUZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7G1-like", "type": "synonym", "evidence": [ { "id": "XP_013845748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845748" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUZ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUZ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100737921", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5", "locus": {} } ], "crossref": [ { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737921", "url": "https://www.ncbi.nlm.nih.gov/gene/100737921", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737921", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737921", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QICFALT", "url": "https://omabrowser.org/oma/group/QICFALT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QUZ5", "url": "https://www.orthodb.org/?gene=A0A5G2QUZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013845748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845748", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QUZ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPRNQTDVSEFLLMRLTEDPELKTIFFRLFLSMYLVTVLGNLLIVLAVISDSHLHTPMYFFLSNLSFTDICLSTTMIPKILVNIRAQNQRISYAGCITQICFVLTFVCWESFLLLVMAYDRYVAICHPLRYTIIMNPRLCGLLTLLSLFISIADALLHSLMVLQLSFCTDLEIPLFFCEVVQVIKLACSDTLINNILIYLAAGVLAGVPLSGIIFSYIQIVSSILRMPSSGRKYKAFSTCGSHLSVVSLFYGTAFGVYISSAVTDSSRKTAVASLMYTVVTPIMNPFIYSLRNRDMKGALKKLISKVLRFL", "length": 312, "header": "tr|A0A5G2QUZ5-1|A0A5G2QUZ5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100737921 PE=3 SV=1 CANONICAL=A0A5G2QUZ5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5/entry#A0A5G2QUZ5-1", "sequence": { "sequence": "MDPRNQTDVSEFLLMRLTEDPELKTIFFRLFLSMYLVTVLGNLLIVLAVISDSHLHTPMYFFLSNLSFTDICLSTTMIPKILVNIRAQNQRISYAGCITQICFVLTFVCWESFLLLVMAYDRYVAICHPLRYTIIMNPRLCGLLTLLSLFISIADALLHSLMVLQLSFCTDLEIPLFFCEVVQVIKLACSDTLINNILIYLAAGVLAGVPLSGIIFSYIQIVSSILRMPSSGRKYKAFSTCGSHLSVVSLFYGTAFGVYISSAVTDSSRKTAVASLMYTVVTPIMNPFIYSLRNRDMKGALKKLISKVLRFL", "length": 312, "header": "tr|A0A5G2QUZ5-1|A0A5G2QUZ5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100737921 PE=3 SV=1 CANONICAL=A0A5G2QUZ5-1" }, "locus": { "chromosome": "2", "start_pos": 67263128, "end_pos": 67262193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082830.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082830.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071500.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071500.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUZ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737921", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737921", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8NGA0-1", "protein_name": "Olfactory receptor 7G1", "gene_name": "OR7G1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPRNQTAVSEFLLMKVTEDPELKLIPFSLFLSMYLVTILGNLLILLAVISDSHLHTPMYFLLFNLSFTDICLTTTTVPKILVNIQAQNQSITYTGCLTQICLVLVFAGLESCFLAVMAYDRYVAICHPLRYTVLMNVHFWGLLILLSMFMSTMDALVQSLMVLQLSFCKNVEIPLFFCEVVQVIKLACSDTLINNILIYFASSVFGAIPLSGIIFSYSQIVTSVLRMPSARGKYKAFSTCGCHLSVFSLFYGTAFGVYISSAVAESSRITAVASVMYTVVPQMMNPFIYSLRNKEMKKALRKLIGRLFPF", "length": 311 }, "evidence": [ { "id": "A0A5G2QUZ5", "url": "https://omabrowser.org/oma/group/A0A5G2QUZ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUZ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUZ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUZ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUZ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QUZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUZ5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QV06-1", "uniprot_ac": "A0A5G2QV06", "uniprot_id": "A0A5G2QV06_PIG", "mass": { "chemical_mass": 34733.0, "monoisotopic_mass": 34733.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QV06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06", "locus": {} } ], "crossref": [ { "id": "A0A5G2QV06", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QV06", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000048497", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000048497", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15952", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15952", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QV06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QV06-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSLNDTPFHPPFFHLLGIPGLETVHLWIAFPFCAVYLIALVGNITILSVIKAEHSLHQPMFYFLAMLSLIDLGLSTSTIPKMLGIFWFNLQEISFGGCLAQMFFIHMFTGMETVLLVAMAYDRFVAICNPLQYTAILTNKTVSILASVVVGRNLILVTPFVFLILRLPFCGHHIIPHTYCEHMGLARLACAPIGINVIYGLMVISNIIVDVVLIASSYVLILRAVFRLPSREARLKALNTCGSHVCVMLCFYTPAFFSFMTHRFGHHIPRYVHILLANLYVVVPPALNPVIYGVRTKHIREMLNPKSY", "length": 309, "header": "tr|A0A5G2QV06-1|A0A5G2QV06_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QV06-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QV06-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06/entry#A0A5G2QV06-1", "sequence": { "sequence": "MPSLNDTPFHPPFFHLLGIPGLETVHLWIAFPFCAVYLIALVGNITILSVIKAEHSLHQPMFYFLAMLSLIDLGLSTSTIPKMLGIFWFNLQEISFGGCLAQMFFIHMFTGMETVLLVAMAYDRFVAICNPLQYTAILTNKTVSILASVVVGRNLILVTPFVFLILRLPFCGHHIIPHTYCEHMGLARLACAPIGINVIYGLMVISNIIVDVVLIASSYVLILRAVFRLPSREARLKALNTCGSHVCVMLCFYTPAFFSFMTHRFGHHIPRYVHILLANLYVVVPPALNPVIYGVRTKHIREMLNPKSY", "length": 309, "header": "tr|A0A5G2QV06-1|A0A5G2QV06_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QV06-1" }, "locus": { "chromosome": "9", "start_pos": 3624914, "end_pos": 3609515, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074835.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074835.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068801.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068801.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QV06-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QV06-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QV06" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QV06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV06" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 293, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QV13-1", "uniprot_ac": "A0A5G2QV13", "uniprot_id": "A0A5G2QV13_PIG", "mass": { "chemical_mass": 34153.0, "monoisotopic_mass": 34153.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV13/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV13#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV13" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV13", "locus": {} } ], "crossref": [ { "id": "A0A5G2QV13", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QV13", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045260", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045260", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QV13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QV13-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSSRDELTARVSNVTEFILLGLTQNPELQKLLFGVLLTTYLITLAGNLLISVTIFISPALASPMYFFLSYLSLIDVFYSSSIAPKMIFDLISGTNTISFKGCMTQLFAEHFFGAVEIVLLIVMAYDRHVAICKPLHYMTIMSPPVCTFLVRMAGALGFIHGGIQVLFMVQLPFCGPNVIDHFMCDLIPLLELACTDTHTLGPLIAANSGSMCLVIFCMLVASYGVILRSLRTHSSEGRHKALSTCASHVTVVILFFVPCSFLYLRPMTSFPTDKAVTVFCTIVTPMLNPLIYTLRNAEVKDALKNSGDK", "length": 310, "header": "tr|A0A5G2QV13-1|A0A5G2QV13_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QV13-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QV13-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV13/entry#A0A5G2QV13-1", "sequence": { "sequence": "MFSSRDELTARVSNVTEFILLGLTQNPELQKLLFGVLLTTYLITLAGNLLISVTIFISPALASPMYFFLSYLSLIDVFYSSSIAPKMIFDLISGTNTISFKGCMTQLFAEHFFGAVEIVLLIVMAYDRHVAICKPLHYMTIMSPPVCTFLVRMAGALGFIHGGIQVLFMVQLPFCGPNVIDHFMCDLIPLLELACTDTHTLGPLIAANSGSMCLVIFCMLVASYGVILRSLRTHSSEGRHKALSTCASHVTVVILFFVPCSFLYLRPMTSFPTDKAVTVFCTIVTPMLNPLIYTLRNAEVKDALKNSGDK", "length": 310, "header": "tr|A0A5G2QV13-1|A0A5G2QV13_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QV13-1" }, "locus": { "chromosome": "AEMK02000159.1", "start_pos": 143737, "end_pos": 142808, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083016.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083016.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062011.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062011.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV13" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV13" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV13" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QV13-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QV13-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QV13" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV13" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 293, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QV38-1", "uniprot_ac": "A0A5G2QV38", "uniprot_id": "A0A5G2QV38_PIG", "mass": { "chemical_mass": 43767.0, "monoisotopic_mass": 43767.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Heterogeneous nuclear ribonucleoprotein K", "type": "recommended", "evidence": [ { "id": "A0A5G2QV38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest. As part of a ribonucleoprotein complex composed at least of ZNF827, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38#function" }, { "database": "UniProtKB", "id": "ARBA00045294", "url": "https://www.uniprot.org/uniprotkb/ARBA00045294#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38", "locus": {} } ], "crossref": [ { "id": "A0A5G2QV38", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QV38", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010221", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010221", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22432", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22432", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22433", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22433", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QV38-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNIKALRTDYNASVSVPDSSGPKRILSISADIETIGEILKKIIPTLEEGSDFDCELRLLIHQSLAGGIIGVKGAKIKEPRENTQTTIKLFQECCPQSTDRVVLIGGKPDRDVECIKIILDLISELPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSVIGKGVLHLFFFYLLLFKKPTFLCFIGVLHLRCSEIFAVHQM", "length": 392, "header": "tr|A0A5G2QV38-1|A0A5G2QV38_PIG Isoform 1 of Heterogeneous nuclear ribonucleoprotein K OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QV38-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QV38-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38/entry#A0A5G2QV38-1", "sequence": { "sequence": "METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNIKALRTDYNASVSVPDSSGPKRILSISADIETIGEILKKIIPTLEEGSDFDCELRLLIHQSLAGGIIGVKGAKIKEPRENTQTTIKLFQECCPQSTDRVVLIGGKPDRDVECIKIILDLISELPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSVIGKGVLHLFFFYLLLFKKPTFLCFIGVLHLRCSEIFAVHQM", "length": 392, "header": "tr|A0A5G2QV38-1|A0A5G2QV38_PIG Isoform 1 of Heterogeneous nuclear ribonucleoprotein K OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QV38-1" }, "locus": { "chromosome": "14", "start_pos": 65845672, "end_pos": 65844151, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067770.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067770.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065823.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065823.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "pmid": "" }, { "name": "podosome", "id": "GO:0002102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002102", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QV38-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 392, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QV38-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QV38" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QV38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV38" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 98, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QV45-1", "uniprot_ac": "A0A5G2QV45", "uniprot_id": "A0A5G2QV45_PIG", "mass": { "chemical_mass": 25608.0, "monoisotopic_mass": 25608.0 }, "refseq": {}, "gene_names": [ { "name": "FOXL3", "type": "recommended", "evidence": [ { "id": "A0A5G2QV45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45" } ] } ], "protein_names": [ { "name": "Forkhead box L3", "type": "synonym", "evidence": [ { "id": "A0A5G2QV45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FOXL3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45", "locus": { "chromosome": "3", "start_pos": 207945, "end_pos": 206348, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000050310", "url": "https://www.ensembl.org/id/ENSSSCG00000050310" } ] } } ], "crossref": [ { "id": "A0A5G2QV45", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QV45", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050310", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050310", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11829:SF211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11829:SF211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QV45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QV45-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFDSSQYPYNCFNYDADDYPAGSSDEEKRLTRPAYSYIALIAMAIQQSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFVKVPRTEGHEKGKGNYWTFAGGCESLLDLFENGNYRRRRRRRGPKREGTRGARAAAAEMPPGPPEPAGARASPAPAPSPRPPASPAALGREEHRDIKFSIDYILSAPDPFPGLKAPCAQEGRCPRREAQPMNLHLWPM", "length": 228, "header": "tr|A0A5G2QV45-1|A0A5G2QV45_PIG Isoform 1 of Forkhead box L3 OS=Sus scrofa OX=9823 GN=FOXL3 PE=4 SV=1 CANONICAL=A0A5G2QV45-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QV45-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45/entry#A0A5G2QV45-1", "sequence": { "sequence": "MFDSSQYPYNCFNYDADDYPAGSSDEEKRLTRPAYSYIALIAMAIQQSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFVKVPRTEGHEKGKGNYWTFAGGCESLLDLFENGNYRRRRRRRGPKREGTRGARAAAAEMPPGPPEPAGARASPAPAPSPRPPASPAALGREEHRDIKFSIDYILSAPDPFPGLKAPCAQEGRCPRREAQPMNLHLWPM", "length": 228, "header": "tr|A0A5G2QV45-1|A0A5G2QV45_PIG Isoform 1 of Forkhead box L3 OS=Sus scrofa OX=9823 GN=FOXL3 PE=4 SV=1 CANONICAL=A0A5G2QV45-1" }, "locus": { "chromosome": "3", "start_pos": 207942, "end_pos": 206547, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091120.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091120.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068713.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068713.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QV45-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 228, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QV45-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QV45" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QV45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV45" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 130, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QV54-1", "uniprot_ac": "A0A5G2QV54", "uniprot_id": "A0A5G2QV54_PIG", "mass": { "chemical_mass": 53317.0, "monoisotopic_mass": 53317.0 }, "refseq": { "ac": "XP_020950238", "name": "gastric inhibitory polypeptide receptor isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950238" }, "gene_names": [ { "name": "GIPR", "type": "recommended", "evidence": [ { "id": "A0A5G2QV54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" } ] }, { "name": "GIPR", "type": "synonym", "evidence": [ { "id": "XP_020950238", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950238" } ] } ], "protein_names": [ { "name": "Gastric inhibitory polypeptide receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QV54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54/entry#names_and_taxonomy" } ] }, { "name": "Glucose-dependent insulinotropic polypeptide receptor", "type": "synonym", "evidence": [ { "id": "A0A5G2QV54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54/entry#names_and_taxonomy" } ] }, { "name": "gastric inhibitory polypeptide receptor isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020950238", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950238" } ] } ], "function": [ { "annotation": "This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54#function" }, { "database": "UniProtKB", "id": "ARBA00059971", "url": "https://www.uniprot.org/uniprotkb/ARBA00059971#function" }, { "database": "UniProtKB", "id": "I3LND8", "url": "https://www.uniprot.org/uniprotkb/I3LND8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GIPR", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54", "locus": { "chromosome": "6", "start_pos": 52033954, "end_pos": 52022681, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021053", "url": "https://www.ensembl.org/id/ENSSSCG00000021053" } ] } } ], "crossref": [ { "id": "A0A5G2QV54", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QV54", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000021053", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000021053", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15929", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15929", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626628", "url": "https://www.ncbi.nlm.nih.gov/gene/100626628", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LNCPPWR", "url": "https://omabrowser.org/oma/group/LNCPPWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR45620", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45620", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45620:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45620:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-420092", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-420092", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020950238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950238", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QV54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QV54-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW90-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LND8", "url": "https://www.uniprot.org/uniprotkb/I3LND8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LND8-1", "url": "https://www.uniprot.org/uniprotkb/I3LND8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNCPPRRLLLLLLLCGPLLRRAEAGSEGQTAGELYQRWERYRRECQETLQAADPLPGLACNGSFDMYVCWDYTAPNATARASCPWYLPWHRHVASGFVLRHCGSDGQWGPWRDHSQCEDPEKNGAFQDQRLILERLQVVYTVGYSLSLATLLLALLILSFFRRLRCTRNYIHINLFTSFMLRAAAILTRDRLLPPPGPYSGDGAPVLWNQALAACRTAQIVTQYCVGANYTWLLVEGIYLHSLLVLVGGSEEGHFRCYMLLGWGAPALFVIPWVIVRYLYEDTQCWERNDIKAIWWIIRTPILLTILINFLIFIRILGILLSKLRTRQMRCPDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRLAKLAFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHRCRLRHSLDEEPRQPRERAFQTLRLGSGHGQVPAGRSPCSRTLPGPGDEASHILESYC", "length": 466, "header": "tr|A0A5G2QV54-1|A0A5G2QV54_PIG Isoform 1 of Gastric inhibitory polypeptide receptor OS=Sus scrofa OX=9823 GN=GIPR PE=3 SV=1 CANONICAL=A0A5G2QV54-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QV54-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54/entry#A0A5G2QV54-1", "sequence": { "sequence": "MRNCPPRRLLLLLLLCGPLLRRAEAGSEGQTAGELYQRWERYRRECQETLQAADPLPGLACNGSFDMYVCWDYTAPNATARASCPWYLPWHRHVASGFVLRHCGSDGQWGPWRDHSQCEDPEKNGAFQDQRLILERLQVVYTVGYSLSLATLLLALLILSFFRRLRCTRNYIHINLFTSFMLRAAAILTRDRLLPPPGPYSGDGAPVLWNQALAACRTAQIVTQYCVGANYTWLLVEGIYLHSLLVLVGGSEEGHFRCYMLLGWGAPALFVIPWVIVRYLYEDTQCWERNDIKAIWWIIRTPILLTILINFLIFIRILGILLSKLRTRQMRCPDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRLAKLAFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHRCRLRHSLDEEPRQPRERAFQTLRLGSGHGQVPAGRSPCSRTLPGPGDEASHILESYC", "length": 466, "header": "tr|A0A5G2QV54-1|A0A5G2QV54_PIG Isoform 1 of Gastric inhibitory polypeptide receptor OS=Sus scrofa OX=9823 GN=GIPR PE=3 SV=1 CANONICAL=A0A5G2QV54-1" }, "locus": { "chromosome": "6", "start_pos": 52032408, "end_pos": 52023781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079120.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079120.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065838.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065838.1" } ] } }, { "isoform_ac": "A0A5G2QW90-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54/entry#A0A5G2QW90-1", "sequence": { "sequence": "MRNCPPRRLLLLLLLCGPLLRRAEAGSEGQTAGELYQRWERYRRECQETLQAADPLPVASGFVLRHCGSDGQWGPWRDHSQCEDPEKNGAFQDQRLILERLQVVYTVGYSLSLATLLLALLILSFFRRLRCTRNYIHINLFTSFMLRAAAILTRDRLLPPPGPYSGDGAPVLWNQALAACRTAQIVTQYCVGANYTWLLVEGIYLHSLLVLVGGSEEGHFRCYMLLGWGAPALFVIPWVIVRYLYEDTQCWERNDIKAIWWIIRTPILLTILINFLIFIRILGILLSKLRTRQMRCPDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRLAKLAFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHRCRLRHSLDEEPRQPRERAFQTLRLGSGHGQVPAGRSPCSRTLPGPGDEASHILESYC", "length": 430, "header": "tr|A0A5G2QW90-1|A0A5G2QW90_PIG Computationally mapped isoform of Gastric inhibitory polypeptide receptor OS=Sus scrofa OX=9823 GN=GIPR PE=3 SV=1 CANONICAL=A0A5G2QV54-1" }, "locus": { "chromosome": "6", "start_pos": 52032408, "end_pos": 52023781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066862.1", "url": "https://www.ensembl.org/id/ENSSSCT00000066862.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062449.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062449.1" } ] } }, { "isoform_ac": "I3LND8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54/entry#I3LND8-1", "sequence": { "sequence": "MRNCPPRRLLLLLLLCGPLLRRAEAGSEGQTAGELYQRWERYRRECQETLQAADPLPGLACNGSFDMYVCWDYTAPNATARASCPWYLPWHRHVASGFVLRHCGSDGQWGPWRDHSQCEDPEKNGAFQDQRLILERLQVVYTVGYSLSLATLLLALLILSFFRRLRCTRNYIHINLFTSFMLRAAAILTRDRLLPPPGPYSGDGAPVLWNQALAACRTAQIVTQYCVGANYTWLLVEGIYLHSLLVLVGGSEEGHFRCYMLLGWGAPALFVIPWVIVRYLYEDTQCWERNDIKAIWWIIRTPILLTILINFLIFIRILGILLSKLRTRQMRCPDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRLAKLAFEIFLSSFQGFLVSVLYCFINKEVGRASAAARALWRSRMERRARRRL", "length": 422, "header": "tr|I3LND8-1|A0A5G2QV54_PIG Computationally mapped isoform of Gastric inhibitory polypeptide receptor OS=Sus scrofa OX=9823 GN=GIPR PE=3 SV=3 CANONICAL=A0A5G2QV54-1" }, "locus": { "chromosome": "6", "start_pos": 52032184, "end_pos": 52023781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023909.3", "url": "https://www.ensembl.org/id/ENSSSCT00000023909.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025612.3", "url": "https://www.ensembl.org/id/ENSSSCP00000025612.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LND8", "url": "https://www.uniprot.org/uniprotkb/I3LND8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-420092", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-420092", "resource": "Reactome", "description": "Glucagon-type ligand receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SW12-1", "protein_name": "Gastric inhibitory polypeptide receptor", "gene_name": "GIPR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPTCPPWWLLLLLSLWEPLLRSAEAGSEGQTAGELYQRWERYRRECQETLEASEPPAGLACNGSFDMYVCWDYTAPNATARASCPWYLPWHGHVAKGFVLRQCGSDGQWGPWRDHSQCENPEKNGVFQDQRLTLERLQVVYTVGYSLSLATLLFALLILSTFRRLRCTRNYIHINLFTSFMLRAAAILTRDRLLPPPGPYPGDQVLTLWNQALVACRTAQIVTQYCVGANYTWLLVEGIYLHSLLVLVGGSEKGHFRCYMLLGWGAPTLFVIPWVIVRYLFENTQCWERNDIKAIWWIIRTPILLTILINFLIFVRILGILVSKLRTRQMRCPDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRLAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHRCRLRHSLSEEPRQRPEPVFRTLPSGSGPGQVASGRALCSRTLPGPGGEANHVLESYC", "length": 466 }, "evidence": [ { "id": "A0A5G2QV54", "url": "https://omabrowser.org/oma/group/A0A5G2QV54/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P43219-1", "protein_name": "Gastric inhibitory polypeptide receptor", "gene_name": "Gipr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLRLLLLLLWLWGLSLQRAETDSEGQTTGELYQRWERYGWECQNTLEATEPPSGLACNGSFDMYACWNYTAANTTARVSCPWYLPWYRQVAAGFVFRQCGSDGQWGSWRDHTQCENPEKNGAFQDQKLILERLQVVYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHMNLFTSFMLRAGAILTRDQLLPPLGPYTGNQTPTLWNQALAACRTAQILTQYCVGANYTWLLVEGVYLHHLLVVVRRSEKGHFRCYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILITILINFLIFIRILGILVSKLRTRQMRCPDYRLRLARSTLTLMPLLGVHEVVFAPVTEEQAEGSLRFAKLAFEIFLSSFQGFLVSVLYCFINKEVQSEIRRLRLSLQEQCPRPHLGQAPRAVPLSSAPQEAAIRNALPSGMLHVPGDEVLESYC", "length": 455 }, "evidence": [ { "id": "A0A5G2QV54", "url": "https://omabrowser.org/oma/group/A0A5G2QV54/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P48546-1", "protein_name": "Gastric inhibitory polypeptide receptor", "gene_name": "GIPR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC", "length": 466 }, "evidence": [ { "id": "A0A5G2QV54", "url": "https://omabrowser.org/oma/group/A0A5G2QV54/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0P543-1", "protein_name": "Gastric inhibitory polypeptide receptor", "gene_name": "Gipr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLRLLLLLLWLWGLQWAETDSEGQTTTGELYQRWEHYGQECQKMLETTEPPSGLACNGSFDMYACWNYTAANTTARVSCPWYLPWFRQVSAGFVFRQCGSDGQWGSWRDHTQCENPEKNGAFQDQTLILERLQIMYTVGYSLSLTTLLLALLILSLFRRLHCTRNYIHMNLFTSFMLRAAAILTRDQLLPPLGPYTGDQAPTPWNQALAACRTAQIMTQYCVGANYTWLLVEGVYLHHLLVIVGRSEKGHFRCYLLLGWGAPALFVIPWVIVRYLRENTQCWERNEVKAIWWIIRTPILITILINFLIFIRILGILVSKLRTRQMRCPDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQVEGSLRFAKLAFEIFLSSFQGFLVSVLYCFINKEVQSEIRQGWRHRRLRLSLQEQRPRPHQELAPRAVPLSSACREAAVGNALPSGMLHVPGDEVLESYC", "length": 460 }, "evidence": [ { "id": "A0A5G2QV54", "url": "https://omabrowser.org/oma/group/A0A5G2QV54/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" } ], "pmid": "" }, { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" } ], "pmid": "" }, { "name": "regulation of insulin secretion", "id": "GO:0050796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050796", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" } ], "pmid": "" }, { "name": "G protein-coupled peptide receptor activity", "id": "GO:0008528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008528", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" } ], "pmid": "" }, { "name": "gastric inhibitory peptide receptor activity", "id": "GO:0016519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016519", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" } ], "pmid": "" }, { "name": "glucagon family peptide binding", "id": "GO:0120022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120022", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QV54-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 466, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QV54-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QV54" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QV54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" }, { "id": "PS50227", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 1", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 122, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QV54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV54" }, { "id": "PS50261", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 2", "eco_id": "ECO_0000259", "start_pos": 137, "end_pos": 396, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QV83-1", "uniprot_ac": "A0A5G2QV83", "uniprot_id": "A0A5G2QV83_PIG", "mass": { "chemical_mass": 35078.0, "monoisotopic_mass": 35078.0 }, "refseq": { "ac": "XP_003355696", "name": "olfactory receptor 8S1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355696" }, "gene_names": [ { "name": "LOC100622479", "type": "recommended", "evidence": [ { "id": "A0A5G2QV83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83" } ] }, { "name": "LOC100622479", "type": "synonym", "evidence": [ { "id": "XP_003355696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355696" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QV83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8S1-like", "type": "synonym", "evidence": [ { "id": "XP_003355696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355696" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100622479", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83", "locus": {} } ], "crossref": [ { "id": "A0A5G2QV83", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QV83", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15229", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15229", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100622479", "url": "https://www.ncbi.nlm.nih.gov/gene/100622479", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100622479", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622479", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TSEWENQ", "url": "https://omabrowser.org/oma/group/TSEWENQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QV83", "url": "https://www.orthodb.org/?gene=A0A5G2QV83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003355696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355696", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QV83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QV83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALRNHSTITEFILIGLSDDPHIEALLFVLFLGIYLLTMRENLMILLIIRADSHLHTPMYFFLRNLSFVDLCFSCVTLPKLLEDLLSEEKTISVEGCLAQVFFVFLTAGNETCLLSVMAYDHYAAICHLLLYGQVMSNQLCVRLVLISWGLASLDAVIIVLLAINLDFCEAQTIYHYTCELPSLLPLSCSDVSIYIDILICSILLHGLGTFLPIFFSYTRIVSTILGISSTTGRSKAFSTCSSHLIAVILFFGSGMLRYLMPPSGSSLDLLFSIQYSVITPMLNPLIYSLKNNEVKTAVKRTLRKYRQYFMV", "length": 312, "header": "tr|A0A5G2QV83-1|A0A5G2QV83_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100622479 PE=3 SV=1 CANONICAL=A0A5G2QV83-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QV83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83/entry#A0A5G2QV83-1", "sequence": { "sequence": "MALRNHSTITEFILIGLSDDPHIEALLFVLFLGIYLLTMRENLMILLIIRADSHLHTPMYFFLRNLSFVDLCFSCVTLPKLLEDLLSEEKTISVEGCLAQVFFVFLTAGNETCLLSVMAYDHYAAICHLLLYGQVMSNQLCVRLVLISWGLASLDAVIIVLLAINLDFCEAQTIYHYTCELPSLLPLSCSDVSIYIDILICSILLHGLGTFLPIFFSYTRIVSTILGISSTTGRSKAFSTCSSHLIAVILFFGSGMLRYLMPPSGSSLDLLFSIQYSVITPMLNPLIYSLKNNEVKTAVKRTLRKYRQYFMV", "length": 312, "header": "tr|A0A5G2QV83-1|A0A5G2QV83_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100622479 PE=3 SV=1 CANONICAL=A0A5G2QV83-1" }, "locus": { "chromosome": "5", "start_pos": 79129470, "end_pos": 79128535, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083980.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083980.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062082.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062082.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100622479", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622479", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MLF2-1", "protein_name": "Olfactory receptor", "gene_name": "OR8S27", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALRNHSTITEFILTGLSDDPHIQALLFVLFLVIYLLTVMGNLTMLLVIRADSHLHTPMYFFLSNLSFLDLCFSCVTLLLKDLLSEKKTISIEGCLAQVFFVFITPGTEVCLLSAMAYDRYAAVCHPLLYSQVMSNQLCVRLVLISWGLASLDAVIIVLLAVNLDFCEAQTIHHYTSELPSLFPLSCSDTSINISILICSILLHGFGTFLPIIFSYAHIVSTILSISSITGRSKAFSTCSSHLIAVILFFGSGMLRYLMPSSGSFLDLLSSLQYSVITPMLNPLIYSFKNKEVKGAVKRTLGKYLHYCTG", "length": 310 }, "evidence": [ { "id": "A0A5G2QV83", "url": "https://omabrowser.org/oma/group/A0A5G2QV83/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QV83-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QV83-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QV83" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QV83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV83" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 288, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVA1-1", "uniprot_ac": "A0A5G2QVA1", "uniprot_id": "A0A5G2QVA1_PIG", "mass": { "chemical_mass": 36406.0, "monoisotopic_mass": 36406.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QVA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1", "locus": {} } ], "crossref": [ { "id": "A0A5G2QVA1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVA1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QVA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRINNQSSLDDFILLGFSDRPWLETPFFVIFLVAYIFALLGNISIILVSHRDPQLDSPMYFFVSNLSLLDLCYTSSTVPQMLVNLQRPEKTISYGGCVAQLYIFLALGSTECILLAIMAFDRYAAICKPLHYPVIMNQRHCIHVATGTWISGFANSLVQSTFTVLTPRCGQRVIDHFFCEVPALLKLACTDTHVNEAELNVLGALLLLVPLTLILGTYVFIARAVMRIRSAESRWKAFNTCASHLLVVSLFYLTAISMYVQPPSSYSHDRGKIMALFYGIVTPTLNPFIYTLRNKDVKAALRRALTKEFWRKKYFKAIFQL", "length": 321, "header": "tr|A0A5G2QVA1-1|A0A5G2QVA1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2QVA1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1/entry#A0A5G2QVA1-1", "sequence": { "sequence": "MRINNQSSLDDFILLGFSDRPWLETPFFVIFLVAYIFALLGNISIILVSHRDPQLDSPMYFFVSNLSLLDLCYTSSTVPQMLVNLQRPEKTISYGGCVAQLYIFLALGSTECILLAIMAFDRYAAICKPLHYPVIMNQRHCIHVATGTWISGFANSLVQSTFTVLTPRCGQRVIDHFFCEVPALLKLACTDTHVNEAELNVLGALLLLVPLTLILGTYVFIARAVMRIRSAESRWKAFNTCASHLLVVSLFYLTAISMYVQPPSSYSHDRGKIMALFYGIVTPTLNPFIYTLRNKDVKAALRRALTKEFWRKKYFKAIFQL", "length": 321, "header": "tr|A0A5G2QVA1-1|A0A5G2QVA1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2QVA1-1" }, "locus": { "chromosome": "AEMK02000435.1", "start_pos": 155986, "end_pos": 144199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090346.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090346.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068773.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068773.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVA1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 321, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVA1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVA1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWE5-1", "uniprot_ac": "A0A5G2QWE5", "uniprot_id": "A0A5G2QWE5_PIG", "mass": { "chemical_mass": 96660.0, "monoisotopic_mass": 96660.0 }, "refseq": {}, "gene_names": [ { "name": "FCHO1", "type": "recommended", "evidence": [ { "id": "A0A5G2QWE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ] } ], "protein_names": [ { "name": "FCH and mu domain containing endocytic adaptor 1", "type": "synonym", "evidence": [ { "id": "A0A5G2QWE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FCHO1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5", "locus": { "chromosome": "2", "start_pos": 59958134, "end_pos": 59990490, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013885", "url": "https://www.ensembl.org/id/ENSSSCG00000013885" } ] } } ], "crossref": [ { "id": "A0A5G2QWE5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWE5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013885", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013885", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23065", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23065", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23065:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23065:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QVA6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5Q5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R678", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R678", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R678-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R678-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R904", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R904", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R904-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R904-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S938", "url": "https://www.uniprot.org/uniprotkb/F1S938", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S938-1", "url": "https://www.uniprot.org/uniprotkb/F1S938-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYFGEHFWGEKNHGFEVLYQSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYSDEQLKTHKKCKEEALGTLDAVQVLAGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAEAKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRQMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPPAAVDSLEPESGTCPEVDEEGFTVRPDVTQNNTEEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDTAGKPQRPRSAPRAGSCAEKPPSDEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHVAPGPSPDSWVPRPGTPQSPRTCRAPPPESRGTQPLPPSDSPQPLAPSPGPWGLEAMAGGDLMPVPADFAAREGLTAPPRRPRSRKVSCPLMRSNGDLSRSLSPSPLGSSAPSTIPERPSFSSQTGHGVSRGPSPVVLGSQDALPVATAFTEYVHAYFRGHTPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTAPIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPAASYYNVMLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYSYRPGATAVPTPLTNVQIVLPIGEPVTNVRLQPAATWNLEEKRLLWKLPDVSEAGGSGRLSASWEPCSGPSTPSPVAAQFTSEGATLSGVDLELVGSGYRMSLIKKRFATGMYLVSC", "length": 887, "header": "tr|A0A5G2QWE5-1|A0A5G2QWE5_PIG Isoform 1 of FCH and mu domain containing endocytic adaptor 1 OS=Sus scrofa OX=9823 GN=FCHO1 PE=3 SV=2 CANONICAL=A0A5G2QWE5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5/entry#A0A5G2QVA6-1", "sequence": { "sequence": "MSYFGEHFWGEKNHGFEVLYQSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYSDEQLKTHKKCKEEALGTLDAVQVLAGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAEAKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRQMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPPAAVDSLEPESGTCPEVDEEGFTVRPDVTQNNTEEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDTAGKPQRPRSAPRAGSCAEKPPSDEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHVAPGPSPDSWVPRPGTPQSPRTCRAPPPESRGTQPLPPSDSPQPLAPSPGPWGLEAMAGGDLMPVPADFAAREGLTAPPRRPRSRKVSCPLMRSNGDLSRSLSPSPLGSSAPSTIPERPSFSSQTGHGVSRGPSPVVLGSQDALPVATAFTEYVHAYFRGHTPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTAPIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPAASYYNVMLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYSYRPGATAVPTPLTNVQIVLPIGEPVTNVRLQPAATWNLEEKRLLWKLPDVSEAGGMYLVSC", "length": 832, "header": "tr|A0A5G2QVA6-1|A0A5G2QWE5_PIG Computationally mapped isoform of FCH and mu domain containing endocytic adaptor 1 OS=Sus scrofa OX=9823 GN=FCHO1 PE=3 SV=1 CANONICAL=A0A5G2QWE5-1" }, "locus": { "chromosome": "2", "start_pos": 59984746, "end_pos": 59958399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075116.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075116.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068060.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068060.1" } ] } }, { "isoform_ac": "A0A5G2QWE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5/entry#A0A5G2QWE5-1", "sequence": { "sequence": "MSYFGEHFWGEKNHGFEVLYQSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYSDEQLKTHKKCKEEALGTLDAVQVLAGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAEAKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRQMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPPAAVDSLEPESGTCPEVDEEGFTVRPDVTQNNTEEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDTAGKPQRPRSAPRAGSCAEKPPSDEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHVAPGPSPDSWVPRPGTPQSPRTCRAPPPESRGTQPLPPSDSPQPLAPSPGPWGLEAMAGGDLMPVPADFAAREGLTAPPRRPRSRKVSCPLMRSNGDLSRSLSPSPLGSSAPSTIPERPSFSSQTGHGVSRGPSPVVLGSQDALPVATAFTEYVHAYFRGHTPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTAPIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPAASYYNVMLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYSYRPGATAVPTPLTNVQIVLPIGEPVTNVRLQPAATWNLEEKRLLWKLPDVSEAGGSGRLSASWEPCSGPSTPSPVAAQFTSEGATLSGVDLELVGSGYRMSLIKKRFATGMYLVSC", "length": 887, "header": "tr|A0A5G2QWE5-1|A0A5G2QWE5_PIG Isoform 1 of FCH and mu domain containing endocytic adaptor 1 OS=Sus scrofa OX=9823 GN=FCHO1 PE=3 SV=2 CANONICAL=A0A5G2QWE5-1" }, "locus": { "chromosome": "2", "start_pos": 59984746, "end_pos": 59958399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071888.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071888.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068475.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068475.2" } ] } }, { "isoform_ac": "A0A5G2R5Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5/entry#A0A5G2R5Q5-1", "sequence": { "sequence": "MSYFGEHFWGEKNHGFEVLYQSVKQGPISTKELADFIRERTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYSDEQLKTHKKCKEEALGTLDAVQVLAGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAEAKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRQMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPPAAVDSLEPESGTCPEVDEEGFTVRPDVTQNSTEEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDTAGKPQRPRSAPRAGSCAEKPPSDEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHVAPGPSPDSWVPRPGTPQSPRTCRAPPPESRGTQPLPPSDSPQPLAPSPGPWGLEAMAGGDLMPVPADFAAREGLTAPPRRPRSRKVSCPLMRSNGDLSRSLSPSPLGSSAPSTIPERPSFSSQTGHGVSRGPSPVVLGSQDALPVATAFTEYVHAYFRGHTPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTAPIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPAASYYNVMLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYSYRPGATAVPTPLTNVQIVLPIGEPVTNVRLQPAATWNLEEKRLLWKLPDVSEAGGSGRLSASWEPCSGPSTPSPVAAQFTSEGATLSGVDLELVGSGYRMSLIKKRFATAPPPQGCT", "length": 863, "header": "tr|A0A5G2R5Q5-1|A0A5G2QWE5_PIG Computationally mapped isoform of FCH and mu domain containing endocytic adaptor 1 OS=Sus scrofa OX=9823 GN=FCHO1 PE=3 SV=2 CANONICAL=A0A5G2QWE5-1" }, "locus": { "chromosome": "2", "start_pos": 59984746, "end_pos": 59958410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086774.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086774.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071655.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071655.2" } ] } }, { "isoform_ac": "A0A5G2R678-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5/entry#A0A5G2R678-1", "sequence": { "sequence": "MSYFGEHFWGEKNHGFEVLYQSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYSDEQLKTHKKVLAGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAEAKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRQMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPPAAVDSLEPESGTCPEVDEEGFTVRPDVTQNNTEEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDTAGKPQRPRSAPRAGSCAEKPPSDEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHVAPGPSPDSWVPRPGTPQSPRTCRAPPPESRGTQPLPPSDSPQPLAPSPGPWGLEAMAGGDLMPVPADFAAREGLTAPPRRPRSRKVSCPLMRSNGDLSRSLSPSPLGSSAPSTIPERPSFSSQTGHGVSRGPSPVVLGSQDALPVATAFTEYVHAYFRGHTPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTAPIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPAASYYNVMLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYSYRPGATAVPTPLTNVQIVLPIGEPVTNVRLQPAATWNLEEKRLLWKLPDVSEAGGSGRLSASWEPCSGPSTPSPVAAQFTSEGATLSGVDLELVGSGYRMSLIKKRFATGMYLVSC", "length": 874, "header": "tr|A0A5G2R678-1|A0A5G2QWE5_PIG Computationally mapped isoform of FCH and mu domain containing endocytic adaptor 1 OS=Sus scrofa OX=9823 GN=FCHO1 PE=3 SV=1 CANONICAL=A0A5G2QWE5-1" }, "locus": { "chromosome": "2", "start_pos": 59984746, "end_pos": 59958399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091237.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091237.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066095.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066095.1" } ] } }, { "isoform_ac": "A0A5G2R6J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5/entry#A0A5G2R6J2-1", "sequence": { "sequence": "MSYFGEHFWGEKNHGFEVLYQSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYSDEQLKTHKKCKEEALGTLDAVQVLAGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAEAKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRQMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPPAAVDSLEPESGTCPEVDEEGFTVRPDVTQNNTEEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDTAGKPQRPRSAPRAGSCAEKPPSDEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHVAPGPSPDSWVPRPGTPQSPRTCRAPPPESRGTQPLPPSDSPQPLAPSPGPWGLEAMAGGDLMPVPADFAAREGLTAPPRRPRSRKVSCPLMRSNGDLSRSLSPSPLGSSAPSTIPERPSFSSQTGHGVSRGPSPVVLGSQDALPVATAFTEYVHAYFRGHTPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTAPIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPAASYYNVMLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYSYRPGATAVPTPLTNVQIVLPIGEPVTNVRLQPAATCPFGGRSDQASLDDDRNLEEKRLLWKLPDVSEAGGELWMCMRAWRSSVGEAYLN", "length": 860, "header": "tr|A0A5G2R6J2-1|A0A5G2QWE5_PIG Computationally mapped isoform of FCH and mu domain containing endocytic adaptor 1 OS=Sus scrofa OX=9823 GN=FCHO1 PE=3 SV=2 CANONICAL=A0A5G2QWE5-1" }, "locus": { "chromosome": "2", "start_pos": 59984746, "end_pos": 59959593, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083772.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083772.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072872.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072872.2" } ] } }, { "isoform_ac": "A0A5G2R904-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5/entry#A0A5G2R904-1", "sequence": { "sequence": "MSYFGEHFWGEKNHGFEVLYQSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYSDEQLKTHKKCKEEALGTLDAVQVLAGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAEAKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRQMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPPAAVDSLEPESGTCPEVDEEGFTVRPDVTQNNTEEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDTAGKPQRPRSAPRAGSCAEKPPSDEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHVAPGPSPDSWVPRPGTPQSPRTCRAPPPESRGTQPLPPSDSPQPLAPSPGPWGLEAMAGGDLMPVPADFAAREGLTAPPRRPRSRKVSCPLMRSNGDLSRSLSPSPLGSSAPSTIPERPSFSSQTGHGVSRGPSPVVLGSQDALPVATAFTEYVHAYFRGHTPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTAPIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPAASYYNVMLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYSYRPGATAVPTPLTNVQIVLPIGEPVTNVRLQPAATWNLEEKRLLWKLPDVSEAGGMALPCCCAPVEPGPCQGCT", "length": 845, "header": "tr|A0A5G2R904-1|A0A5G2QWE5_PIG Computationally mapped isoform of FCH and mu domain containing endocytic adaptor 1 OS=Sus scrofa OX=9823 GN=FCHO1 PE=3 SV=1 CANONICAL=A0A5G2QWE5-1" }, "locus": { "chromosome": "2", "start_pos": 59984746, "end_pos": 59958410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090634.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090634.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073561.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073561.1" } ] } }, { "isoform_ac": "A0A5G2RMN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5/entry#A0A5G2RMN3-1", "sequence": { "sequence": "MSYFGEHFWGEKNHGFEVLYQSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYSDEQLKTHKKCKEEALGTLDAVQVLAGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAEAKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRQMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPPAAVDSLEPESGTCPEVDEEGFTVRPDVTQNNTEEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDTAGKPQRPRSAPRAGSCAEKPPSDEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHVAPGPSPDSWVPRPGTPQSPRTCRAPPPESRGTQPLPPSDSPQPLAPSPGPWGLEAMAGGDLMPVPADFAAREGLTAPPRRPRSRKVSCPLMRSNGDLSRSLSPSPLGSSAPSTIPERPSFSSQTGHGVSRGPSPVVLGSQDALPVATAFTEYVHAYFRGHTPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTAPIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPAASYYNVMLLRYQEPGREEAPMEASRCVRGRGFWPPICQLGAMFGAQHAQPCSRSVHQRGGHSIWCGPGAGGEWLPHVLDKEEVRHRDVPSELLILQRPTSTAGPSSVLHPGAR", "length": 841, "header": "tr|A0A5G2RMN3-1|A0A5G2QWE5_PIG Computationally mapped isoform of FCH and mu domain containing endocytic adaptor 1 OS=Sus scrofa OX=9823 GN=FCHO1 PE=3 SV=2 CANONICAL=A0A5G2QWE5-1" }, "locus": { "chromosome": "2", "start_pos": 59984746, "end_pos": 59958337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069554.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069554.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073884.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073884.2" } ] } }, { "isoform_ac": "F1S938-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5/entry#F1S938-1", "sequence": { "sequence": "MSYFGEHFWGEKNHGFEVLYQSVKQGPISTKELADFIRERTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYSDEQLKTHKKCKEEALGTLDAVQVLAGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAEAKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRQMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPPAAVDSLEPESGTCPEVDEEGFTVRPDVTQNSTEEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDTAGKPQRPRSAPRAGSCAEKPPSDEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHVAPGPSPDSWVPRPGTPQSPRTCRAPPPESRGTQPLPPSDSPQPLAPSPGPWGLEAMAGGDLMPVPADFAAREGLTAPPRRPRSRKVSCPLMRSNGDLSRSLSPSPLGSSAPSTIPERPSFSSQTGHGVSRGPSPVVLGSQDALPVATAFTEYVHAYFRGHTPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTAPIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPAASYYNVMLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYSYRPGATAVPTPLTNVQIVLPIGEPVTNVRLQPAATWNLEEKRLLWKLPDVSEAGGSGRLSASWEPCSGPSTPSPVAAQFTSEGATLSGVDLELVGSGYRMSLIKKRFATGMYLVSC", "length": 862, "header": "tr|F1S938-1|F1S938_PIG Computationally mapped isoform of FCH and mu domain containing endocytic adaptor 1 OS=Sus scrofa OX=9823 GN=FCHO1 PE=4 SV=4 CANONICAL=A0A5G2QWE5-1" }, "locus": { "chromosome": "2", "start_pos": 59984746, "end_pos": 59958399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015171.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015171.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014765.5", "url": "https://www.ensembl.org/id/ENSSSCP00000014765.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 842, "start_aa": "Thr", "end_pos": 842, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr842", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVA6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVA6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-SSC-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "pmid": "" }, { "name": "clathrin coat assembly", "id": "GO:0048268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048268", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "pmid": "" }, { "name": "positive regulation of T cell activation", "id": "GO:0050870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050870", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "AP-2 adaptor complex binding", "id": "GO:0035612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035612", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWE5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 887, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWE5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWE5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" }, { "id": "PS51741", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51741" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-BAR", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 248, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QWE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE5" }, { "id": "PS51072", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51072" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MHD", "eco_id": "ECO_0000259", "start_pos": 623, "end_pos": 886, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 842 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 242, "end_pos": 244 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVF6-1", "uniprot_ac": "A0A5G2QVF6", "uniprot_id": "A0A5G2QVF6_PIG", "mass": { "chemical_mass": 44434.0, "monoisotopic_mass": 44434.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QVF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6", "locus": {} } ], "crossref": [ { "id": "A0A5G2QVF6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10489:SF951", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10489:SF951", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QVF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "REDLNTPSSQPGYWPRVTGAGATLALRALIAGAYLALCAVGLVGNTLVLVLVRAQQWRRRSLLNCFILNLAATDLQFVLTLPFWAADTVRDFSWPFGGAMCKVVLTLTVLNMYASSFFLSAMSMDRYRTVANALRPRQPGTPWAVCVCCLLWAIAVLATAPTALFATAARVGDERLCLLRFPDGGPDWLAFYHLQKIAVAFVLPLATLGICSLLLLRFLRRRVWPRRRSQVTRVLACVLLSFVLCWLPNQALTLWGVLIKLNAVPWDRAYFLAQAYLFPVSICLAHSNSCLNPLLYCLLRSDFRQSLRKLCGWAKPPADLRPGRTAVPQLLRSPTRPEDREVHLSVRTTLRSIVPRVVGQIMSLGTGPMKSSSSVCLQSLCSGVYWRGCIGPLAVETESCH", "length": 401, "header": "tr|A0A5G2QVF6-1|A0A5G2QVF6_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QVF6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6/entry#A0A5G2QVF6-1", "sequence": { "sequence": "REDLNTPSSQPGYWPRVTGAGATLALRALIAGAYLALCAVGLVGNTLVLVLVRAQQWRRRSLLNCFILNLAATDLQFVLTLPFWAADTVRDFSWPFGGAMCKVVLTLTVLNMYASSFFLSAMSMDRYRTVANALRPRQPGTPWAVCVCCLLWAIAVLATAPTALFATAARVGDERLCLLRFPDGGPDWLAFYHLQKIAVAFVLPLATLGICSLLLLRFLRRRVWPRRRSQVTRVLACVLLSFVLCWLPNQALTLWGVLIKLNAVPWDRAYFLAQAYLFPVSICLAHSNSCLNPLLYCLLRSDFRQSLRKLCGWAKPPADLRPGRTAVPQLLRSPTRPEDREVHLSVRTTLRSIVPRVVGQIMSLGTGPMKSSSSVCLQSLCSGVYWRGCIGPLAVETESCH", "length": 401, "header": "tr|A0A5G2QVF6-1|A0A5G2QVF6_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QVF6-1" }, "locus": { "chromosome": "7", "start_pos": 48012000, "end_pos": 48010589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080202.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080202.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068105.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068105.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6" } ], "pmid": "" }, { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6" } ], "pmid": "" }, { "name": "cell chemotaxis", "id": "GO:0060326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060326", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "C-C chemokine receptor activity", "id": "GO:0016493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016493", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6" } ], "pmid": "" }, { "name": "C-C chemokine binding", "id": "GO:0019957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019957", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVF6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 401, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVF6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVF6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 296, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVG4-1", "uniprot_ac": "A0A5G2QVG4", "uniprot_id": "A0A5G2QVG4_PIG", "mass": { "chemical_mass": 37258.0, "monoisotopic_mass": 37258.0 }, "refseq": {}, "gene_names": [ { "name": "EMB", "type": "recommended", "evidence": [ { "id": "A0A5G2QVG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG4" } ] } ], "protein_names": [ { "name": "Embigin", "type": "recommended", "evidence": [ { "id": "A0A5G2QVG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EMB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG4", "locus": { "chromosome": "16", "start_pos": 30120493, "end_pos": 30287793, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000029484", "url": "https://www.ensembl.org/id/ENSSSCG00000029484" } ] } } ], "crossref": [ { "id": "A0A5G2QVG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000029484", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000029484", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QVG4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L5I2", "url": "https://www.uniprot.org/uniprotkb/I3L5I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L5I2-1", "url": "https://www.uniprot.org/uniprotkb/I3L5I2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSLPGLRGPQAPSLPLLLLGLLAAVRRSLEDGHPSASPFTSPPIQEEMMTKYSNLSLESHNISLTEHSNKPVEKNITLERPSNIELTCQFTTSRDLNSVNVTWKKDDELLKNNYLINVTGRLLYTQYMFTIVNSKQMGSYSCFFEEKKEQRGTFNFKVPQLNGKNKPLITYVGDSVVLMCKCKDCLPLNWTWYSSNGSVQVPVGVQTNDKYVINGKNANETRLKIMQLSEEDQGSYWCHAIFQLGESEEHIELVVLSYLVPLKAFLAIAAEVVLLVAIILLCEMYTQKRKKPSDDGKEFEQIEQLKSDDSNGIENNATRHRKNESVSQ", "length": 329, "header": "tr|A0A5G2QVG4-1|A0A5G2QVG4_PIG Isoform 1 of Embigin OS=Sus scrofa OX=9823 GN=EMB PE=4 SV=2 CANONICAL=A0A5G2QVG4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG4/entry#A0A5G2QVG4-1", "sequence": { "sequence": "MRSLPGLRGPQAPSLPLLLLGLLAAVRRSLEDGHPSASPFTSPPIQEEMMTKYSNLSLESHNISLTEHSNKPVEKNITLERPSNIELTCQFTTSRDLNSVNVTWKKDDELLKNNYLINVTGRLLYTQYMFTIVNSKQMGSYSCFFEEKKEQRGTFNFKVPQLNGKNKPLITYVGDSVVLMCKCKDCLPLNWTWYSSNGSVQVPVGVQTNDKYVINGKNANETRLKIMQLSEEDQGSYWCHAIFQLGESEEHIELVVLSYLVPLKAFLAIAAEVVLLVAIILLCEMYTQKRKKPSDDGKEFEQIEQLKSDDSNGIENNATRHRKNESVSQ", "length": 329, "header": "tr|A0A5G2QVG4-1|A0A5G2QVG4_PIG Isoform 1 of Embigin OS=Sus scrofa OX=9823 GN=EMB PE=4 SV=2 CANONICAL=A0A5G2QVG4-1" }, "locus": { "chromosome": "16", "start_pos": 30170210, "end_pos": 30127264, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078771.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078771.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068115.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068115.2" } ] } }, { "isoform_ac": "I3L5I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG4/entry#I3L5I2-1", "sequence": { "sequence": "MDIFGGHYSANHNMERVEASPFTSPPIQEEMMTKYSNLSLESHNISLTEHSNKPVEKNITLERPSNIELTCQFTTSRDLNSVNVTWKKDDELLKNNYLINVTGRLLYTQYMFTIVNSKQMGSYSCFFEEKKEQRGTFNFKVPQLNGKNKPLITYVGDSVVLMCKCKDCLPLNWTWYSSNGSVQVPVGVQTNDKYVINGKNANETRLKIMQLSEEDQGSYWCHAIFQLGESEEHIELVVLSYLVPLKAFLAIAAEVVLLVAIILLCEMYTQKRKKPSDDGKEFEQIEQLKSDDSNGIENNATRHRKNESVSQ", "length": 311, "header": "tr|I3L5I2-1|A0A5G2QVG4_PIG Computationally mapped isoform of Embigin OS=Sus scrofa OX=9823 GN=EMB PE=4 SV=3 CANONICAL=A0A5G2QVG4-1" }, "locus": { "chromosome": "16", "start_pos": 30245110, "end_pos": 30127264, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030477.3", "url": "https://www.ensembl.org/id/ENSSSCT00000030477.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019281.3", "url": "https://www.ensembl.org/id/ENSSSCP00000019281.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3L5I2", "url": "https://www.uniprot.org/uniprotkb/I3L5I2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVG4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 329, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVG4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVG4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG4" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 143, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 118, "end_pos": 120 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 55, "end_pos": 57 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVG6-1", "uniprot_ac": "A0A5G2QVG6", "uniprot_id": "A0A5G2QVG6_PIG", "mass": { "chemical_mass": 91070.0, "monoisotopic_mass": 91070.0 }, "refseq": {}, "gene_names": [ { "name": "DPP10", "type": "recommended", "evidence": [ { "id": "A0A5G2QVG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6" } ] } ], "protein_names": [ { "name": "Dipeptidyl peptidase like 10", "type": "synonym", "evidence": [ { "id": "A0A5G2QVG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DPP10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6", "locus": { "chromosome": "15", "start_pos": 22011994, "end_pos": 20619441, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015711", "url": "https://www.ensembl.org/id/ENSSSCG00000015711" } ] } } ], "crossref": [ { "id": "A0A5G2QVG6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVG6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015711", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015711", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11731", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11731", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11731:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11731:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00930", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00930", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QVG6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RY14", "url": "https://www.uniprot.org/uniprotkb/F1RY14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RY14-1", "url": "https://www.uniprot.org/uniprotkb/F1RY14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAMKQEQQPTPGARASQAQPADQELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELTNSSETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIANATTLLLENTTFVTFKASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSILQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEGIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPNMVIPRFTGALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPTHTLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRPQNISILTVCETTTGACSRKYEMTSDTWLFKQNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLVQSKSEQIIVRHLTSGNWEVIKILAYDESTQKIYFLSTESSPRGRQLYSASTEGLLNRQCISCNFMKEQCTYFGASFSPMNQHFLLFCKGPGVPVVSLHSTDNPTKYFILENNSMLKDTILKKKIVKSEIKTLHIDDYELPLQLSFPKDFTDRNQYALLLIMDEEPGGQLVTDKFHVDWDSVLVDTDNVIIARFDGRGSGFQGLKILQEIHRRLGSVDVKDQIAAVKFLLKQPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVIAPIVDLKLYASAFSERYLGLPSKEESTYQASSVLHNIHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSEKSKYHLYSTILRFFSDCLKEEIPLLPQEPEEDE", "length": 799, "header": "tr|A0A5G2QVG6-1|A0A5G2QVG6_PIG Isoform 1 of Dipeptidyl peptidase like 10 OS=Sus scrofa OX=9823 GN=DPP10 PE=4 SV=1 CANONICAL=A0A5G2QVG6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6/entry#A0A5G2QVG6-1", "sequence": { "sequence": "MTAMKQEQQPTPGARASQAQPADQELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELTNSSETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIANATTLLLENTTFVTFKASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSILQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEGIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPNMVIPRFTGALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPTHTLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRPQNISILTVCETTTGACSRKYEMTSDTWLFKQNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLVQSKSEQIIVRHLTSGNWEVIKILAYDESTQKIYFLSTESSPRGRQLYSASTEGLLNRQCISCNFMKEQCTYFGASFSPMNQHFLLFCKGPGVPVVSLHSTDNPTKYFILENNSMLKDTILKKKIVKSEIKTLHIDDYELPLQLSFPKDFTDRNQYALLLIMDEEPGGQLVTDKFHVDWDSVLVDTDNVIIARFDGRGSGFQGLKILQEIHRRLGSVDVKDQIAAVKFLLKQPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVIAPIVDLKLYASAFSERYLGLPSKEESTYQASSVLHNIHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSEKSKYHLYSTILRFFSDCLKEEIPLLPQEPEEDE", "length": 799, "header": "tr|A0A5G2QVG6-1|A0A5G2QVG6_PIG Isoform 1 of Dipeptidyl peptidase like 10 OS=Sus scrofa OX=9823 GN=DPP10 PE=4 SV=1 CANONICAL=A0A5G2QVG6-1" }, "locus": { "chromosome": "15", "start_pos": 22009733, "end_pos": 21366282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066605.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066605.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068963.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068963.1" } ] } }, { "isoform_ac": "A0A5G2R9H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6/entry#A0A5G2R9H0-1", "sequence": { "sequence": "MRKVESRGEGGREELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELTNSSETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIANATTLLLENTTFVTFKASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSILQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEGIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPNMVIPRFTGALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPTHTLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRPQNISILTVCETTTGACSRKYEMTSDTWLFKQNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLVQSKSEQIIVRHLTSGNWEVIKILAYDESTQKIYFLSTESSPRGRQLYSASTEGLLNRQCISCNFMKEQCTYFGASFSPMNQHFLLFCKGPGVPVVSLHSTDNPTKYFILENNSMLKDTILKKKIVKSEIKTLHIDDYELPLQLSFPKDFTDRNQYALLLIMDEEPGGQLVTDKFHVDWDSVLVDTDNVIIARFDGRGSGFQGLKILQEIHRRLGSVDVKDQIAAVKFLLKQPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVIAPIVDLKLYASAFSERYLGLPSKEESTYQASSVLHNIHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSEKSKYHLYSTILRFFSDCLKEEIPLLPQEPEEDE", "length": 788, "header": "tr|A0A5G2R9H0-1|A0A5G2QVG6_PIG Computationally mapped isoform of Dipeptidyl peptidase like 10 OS=Sus scrofa OX=9823 GN=DPP10 PE=4 SV=1 CANONICAL=A0A5G2QVG6-1" }, "locus": { "chromosome": "15", "start_pos": 22009733, "end_pos": 21366556, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067526.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067526.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073716.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073716.1" } ] } }, { "isoform_ac": "F1RY14-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6/entry#F1RY14-1", "sequence": { "sequence": "MNQTASVSHHIKCQPSKTIKELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELTNSSETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIANATTLLLENTTFVTFKASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSILQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEGIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPNMVIPRFTGALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPTHTLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRPQNISILTVCETTTGACSRKYEMTSDTWLFKQNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLVQSKSEQIIVRHLTSGNWEVIKILAYDESTQKIYFLSTESSPRGRQLYSASTEGLLNRQCISCNFMKEQCTYFGASFSPMNQHFLLFCKGPGVPVVSLHSTDNPTKYFILENNSMLKDTILKKKIVKSEIKTLHIDDYELPLQLSFPKDFTDRNQYALLLIMDEEPGGQLVTDKFHVDWDSVLVDTDNVIIARFDGRGSGFQGLKILQEIHRRLGSVDVKDQIAAVKFLLKQPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVIAPIVDLKLYASAFSERYLGLPSKEESTYQASSVLHNIHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSEKSKYHLYSTILRFFSDCLKEEIPLLPQEPEEDE", "length": 795, "header": "tr|F1RY14-1|A0A5G2QVG6_PIG Computationally mapped isoform of Dipeptidyl peptidase like 10 OS=Sus scrofa OX=9823 GN=DPP10 PE=4 SV=4 CANONICAL=A0A5G2QVG6-1" }, "locus": { "chromosome": "15", "start_pos": 22009733, "end_pos": 20619778, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017111.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017111.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016651.4", "url": "https://www.ensembl.org/id/ENSSSCP00000016651.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 11, "start_aa": "Thr", "end_pos": 11, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr11", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of potassium ion transmembrane transport", "id": "GO:1901379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901379", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6" } ], "pmid": "" }, { "name": "positive regulation of protein localization to plasma membrane", "id": "GO:1903078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903078", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 751, "end_pos": 753, "annotation": "n_glycosylation_sequon" }, { "start_pos": 763, "end_pos": 765, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVG6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 799, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVG6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVG6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6" }, { "id": "PF00930", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00930" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dipeptidylpeptidase IV N-terminal", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 502, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QVG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG6" }, { "id": "PF00326", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S9 prolyl oligopeptidase catalytic", "eco_id": "ECO_0000259", "start_pos": 584, "end_pos": 786, "start_aa": "His", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 11 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 122, "end_pos": 124 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 520, "end_pos": 522 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 751, "end_pos": 753 }, { "start_pos": 763, "end_pos": 765 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVJ3-1", "uniprot_ac": "A0A5G2QVJ3", "uniprot_id": "A0A5G2QVJ3_PIG", "mass": { "chemical_mass": 34143.0, "monoisotopic_mass": 34143.0 }, "refseq": { "ac": "XP_003482552", "name": "olfactory receptor 481-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482552" }, "gene_names": [ { "name": "LOC100737844", "type": "synonym", "evidence": [ { "id": "XP_003482552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482552" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QVJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 481-like", "type": "synonym", "evidence": [ { "id": "XP_003482552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482552" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3", "locus": {} } ], "crossref": [ { "id": "A0A5G2QVJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100737844", "url": "https://www.ncbi.nlm.nih.gov/gene/100737844", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737844", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737844", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MVTEFVI", "url": "https://omabrowser.org/oma/group/MVTEFVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QVJ3", "url": "https://www.orthodb.org/?gene=A0A5G2QVJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003482552", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482552", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVGNHTMVTEFIILGLTENPSLRSVFSVVFLGIYIATILGNVSIIVLIQSSPQLHTPMYLFLSHLAFVDIGYSSSVTPVMVVSFLKEKLTMPVAGCIAQLGCDVVFGTAECFLLAAMAYDRYVAVCFPLLYSTHMSPRVCILLLVASYLGGCANAASFTGCLLSLTFCGPNKIDHFFCDLPPLVELSCTHRYAAERSPAVSAGSIIVLTLCAIIFSYLYIVHSILGMHSAEGRHKAFSTCTSHLTAVTLFYGTVTFVYVLPKSSHAADHIKVVSLFYTVVVPVLNPLIYSLRNKEVKEAMRKLMVRTHQSF", "length": 312, "header": "tr|A0A5G2QVJ3-1|A0A5G2QVJ3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QVJ3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3/entry#A0A5G2QVJ3-1", "sequence": { "sequence": "MEVGNHTMVTEFIILGLTENPSLRSVFSVVFLGIYIATILGNVSIIVLIQSSPQLHTPMYLFLSHLAFVDIGYSSSVTPVMVVSFLKEKLTMPVAGCIAQLGCDVVFGTAECFLLAAMAYDRYVAVCFPLLYSTHMSPRVCILLLVASYLGGCANAASFTGCLLSLTFCGPNKIDHFFCDLPPLVELSCTHRYAAERSPAVSAGSIIVLTLCAIIFSYLYIVHSILGMHSAEGRHKAFSTCTSHLTAVTLFYGTVTFVYVLPKSSHAADHIKVVSLFYTVVVPVLNPLIYSLRNKEVKEAMRKLMVRTHQSF", "length": 312, "header": "tr|A0A5G2QVJ3-1|A0A5G2QVJ3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QVJ3-1" }, "locus": { "chromosome": "9", "start_pos": 1917623, "end_pos": 1916688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068081.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068081.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068883.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068883.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737844", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737844", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZNI0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPGNHTMVTEFIILGLTEDPTLCCIFFVLFLGVYLTTVLGNASIIMLIRRSPQLHTPMYLFLSHLAFVDIGYSSSVTPVMIVNFLRERTAIPVAGCIVQLGSDVVFGTAECFLLAAMAYDRYVAICSPLRYSTLMSSRVCFILLVISYAGGCVNSSSFTSCLLSLTFCGPNKINHFFCDLPPLVELSCTHVYIADMSPAISAGSIIVITLFIIIISYVYILRSILRMRSTEGRHKAFSTCTSHLTAVTLFYGTVTFVYVIPKSSHSPDQIKVVSVFHTVVIPMLNPLTYSLRNKEVKEAMRKLMARTHSSY", "length": 312 }, "evidence": [ { "id": "A0A5G2QVJ3", "url": "https://omabrowser.org/oma/group/A0A5G2QVJ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TRV2-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGNHTMVTEFIILGLTENPTLCCIFFVLFLGVYLTTILGNVSIIMLIRRSPQLHTPMYLFLSHLAFVDIGYSSSVTPVMIVSFLRERTAIPVAGCIVQLGSDVVFGTAECFLLAAMAYDRYVAICSPLLYSTLMSPKVCLILLVISYVGGCVNSSSFTSCLLSLTFCGPNKVNHFFCDLPPLVELSCTHVYVAEMSPAISAGSIIVITLFVIIISYVYILHSILRMRSTEGRHKAFSTCTSHLTAVTLFYGTVTFVYVIPESSHSPNKIKVVSVFYTVVIPMLNPLIYSLRNKEVKEAMRKLMA", "length": 306 }, "evidence": [ { "id": "A0A5G2QVJ3", "url": "https://omabrowser.org/oma/group/A0A5G2QVJ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVJ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVJ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVJ3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVJ3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVM5-1", "uniprot_ac": "A0A5G2QVM5", "uniprot_id": "A0A5G2QVM5_PIG", "mass": { "chemical_mass": 23670.0, "monoisotopic_mass": 23670.0 }, "refseq": {}, "gene_names": [ { "name": "FXYD4", "type": "recommended", "evidence": [ { "id": "A0A5G2QVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5" } ] } ], "protein_names": [ { "name": "FXYD domain-containing ion transport regulator", "type": "recommended", "evidence": [ { "id": "A0A5G2QVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Increases the apparent affinity of the transporter for Na(+) and increases NKA activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5#function" }, { "database": "UniProtKB", "id": "ARBA00054079", "url": "https://www.uniprot.org/uniprotkb/ARBA00054079#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FXYD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5", "locus": {} } ], "crossref": [ { "id": "A0A5G2QVM5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044108", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044108", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20322", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20322", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14132:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14132:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QVM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYGVGQRCGLEPPLMWLWPKRVAIALIRPLRWEPPYAASVALEKTKKKKEREGYMAHLSPTITSASEQAWGPSLCLVLSVAGIVALGGATGFKSRNPPGLKCSPCSLHRPALGTRLSGALRRRLSALSCNCVMEGVTRGLLLLLAGLPILEASNLVADKDSPFYYDWEGLQLGGMICAALMCIIGIAFALSGKCKCKQNQKHSPLPEKAVPLIAPGSASAC", "length": 222, "header": "tr|A0A5G2QVM5-1|A0A5G2QVM5_PIG Isoform 1 of FXYD domain-containing ion transport regulator OS=Sus scrofa OX=9823 GN=FXYD4 PE=3 SV=2 CANONICAL=A0A5G2QVM5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5/entry#A0A5G2QVM5-1", "sequence": { "sequence": "MSYGVGQRCGLEPPLMWLWPKRVAIALIRPLRWEPPYAASVALEKTKKKKEREGYMAHLSPTITSASEQAWGPSLCLVLSVAGIVALGGATGFKSRNPPGLKCSPCSLHRPALGTRLSGALRRRLSALSCNCVMEGVTRGLLLLLAGLPILEASNLVADKDSPFYYDWEGLQLGGMICAALMCIIGIAFALSGKCKCKQNQKHSPLPEKAVPLIAPGSASAC", "length": 222, "header": "tr|A0A5G2QVM5-1|A0A5G2QVM5_PIG Isoform 1 of FXYD domain-containing ion transport regulator OS=Sus scrofa OX=9823 GN=FXYD4 PE=3 SV=2 CANONICAL=A0A5G2QVM5-1" }, "locus": { "chromosome": "14", "start_pos": 61637557, "end_pos": 61633188, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077499.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077499.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068195.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068195.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5" } ], "pmid": "" }, { "name": "regulation of monoatomic ion transport", "id": "GO:0043269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043269", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ion channel regulator activity", "id": "GO:0099106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099106", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVM5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 222, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVM5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVM5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVN7-1", "uniprot_ac": "A0A5G2QVN7", "uniprot_id": "A0A5G2QVN7_PIG", "mass": { "chemical_mass": 51176.0, "monoisotopic_mass": 51176.0 }, "refseq": {}, "gene_names": [ { "name": "FKBP4", "type": "recommended", "evidence": [ { "id": "A0A5G2QVN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7" } ] } ], "protein_names": [ { "name": "peptidylprolyl isomerase", "type": "recommended", "evidence": [ { "id": "A0A5G2QVN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7/entry#names_and_taxonomy" } ] }, { "name": "5.2.1.8", "type": "synonym", "evidence": [ { "id": "A0A5G2QVN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVN7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FKBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7", "locus": { "chromosome": "5", "start_pos": 67313480, "end_pos": 67322028, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000743", "url": "https://www.ensembl.org/id/ENSSSCG00000000743" } ] } } ], "crossref": [ { "id": "A0A5G2QVN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000743", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000743", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FGAEGNE", "url": "https://omabrowser.org/oma/group/FGAEGNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46512", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46512", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46512:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46512:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00254", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00254", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3371497", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371497", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3371568", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371568", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8939211", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939211", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9018519", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018519", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QVN7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SK86", "url": "https://www.uniprot.org/uniprotkb/F1SK86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SK86-1", "url": "https://www.uniprot.org/uniprotkb/F1SK86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAEETKTAENGAQSAPLPLEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVSVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYARPNDGAIVEVALEGYYKDQIFDQREIRFEVGEGETMDLPCGLEKAIQRMEKGEHSIVYLKPSYAFGSAGKEKFHIPPNAELKYEVHLKSFEKAKESWEMSSEEKLEQSSIVKERGTVYFKEGKYKQALVQYKKIVSWLEYESSFSNEDAQKAQALRLASHLNLAMCYLKLQSFSAAIENCNKALELDSNNEKGFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKAQLALCQQRIRKQLAREKKLYANMFERLAEEESKAKVSGDQQADTEMKEEQKNDVAGRQPQVEAEA", "length": 455, "header": "tr|A0A5G2QVN7-1|A0A5G2QVN7_PIG Isoform 1 of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=FKBP4 PE=1 SV=1 CANONICAL=A0A5G2QVN7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7/entry#A0A5G2QVN7-1", "sequence": { "sequence": "MTAEETKTAENGAQSAPLPLEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVSVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYARPNDGAIVEVALEGYYKDQIFDQREIRFEVGEGETMDLPCGLEKAIQRMEKGEHSIVYLKPSYAFGSAGKEKFHIPPNAELKYEVHLKSFEKAKESWEMSSEEKLEQSSIVKERGTVYFKEGKYKQALVQYKKIVSWLEYESSFSNEDAQKAQALRLASHLNLAMCYLKLQSFSAAIENCNKALELDSNNEKGFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKAQLALCQQRIRKQLAREKKLYANMFERLAEEESKAKVSGDQQADTEMKEEQKNDVAGRQPQVEAEA", "length": 455, "header": "tr|A0A5G2QVN7-1|A0A5G2QVN7_PIG Isoform 1 of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=FKBP4 PE=1 SV=1 CANONICAL=A0A5G2QVN7-1" }, "locus": { "chromosome": "5", "start_pos": 67321558, "end_pos": 67314121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085969.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085969.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065998.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065998.1" } ] } }, { "isoform_ac": "F1SK86-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7/entry#F1SK86-1", "sequence": { "sequence": "MTAEETKTAENGAQSAPLPLEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVSVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYARPNDGAIVEVALEGYYKDQIFDQREIRFEVGEGETMDLPCGLEKAIQRMEKGEHSIVYLKPSYAFGSAGKEKFHIPPNAELKYEVHLKSFEKAKESWEMSSEEKLEQSSIVKERGTVYFKEGKYKQALVQYKKIVSWLEYESSFSNEDAQKAQALRLASHLNLAMCYLKLQSFSAAIENCNKVLQLYPSNKAAKAQLALCQQRIRKQLAREKKLYANMFERLAEEESKAKVSGDQQADTEMKEEQKNDVAGRQPQVEAEA", "length": 422, "header": "tr|F1SK86-1|F1SK86_PIG Computationally mapped isoform of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=FKBP4 PE=1 SV=3 CANONICAL=A0A5G2QVN7-1" }, "locus": { "chromosome": "5", "start_pos": 67321558, "end_pos": 67314121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000807.5", "url": "https://www.ensembl.org/id/ENSSSCT00000000807.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000791.4", "url": "https://www.ensembl.org/id/ENSSSCP00000000791.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVN7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3371497", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371497", "resource": "Reactome", "description": "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" }, { "id": "R-SSC-3371568", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371568", "resource": "Reactome", "description": "Attenuation phase" }, { "id": "R-SSC-8939211", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939211", "resource": "Reactome", "description": "ESR-mediated signaling" }, { "id": "R-SSC-9018519", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018519", "resource": "Reactome", "description": "Estrogen-dependent gene expression" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q2U9P1-1", "protein_name": "peptidylprolyl isomerase", "gene_name": "FKBP4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTAEEMKADGAPLEGTDITPKRDEGVLKVVKREGTGTESPMIGDKVTVHYTGWLLDGTKFDSSLDRRDKFSFDLGKGEVIKAWDIAVATMKVGEICQITCKPEYAYGLAGSPPKIPPNATLIFEIELFEFKGEDLTDDEDGGIIRRIRKKGEGYLKPNEGALVEIQFEGRYRDRAFDKRELRFEIGEGDNYDLPHGLEKAIQKMEKSEESIFYLKPNYGFGSTGKEKFQIPPDAELQYEVKLKSFEKAKESWEMNTEEKLEQSCMVKERGTQYFKEGKYKRAALQYKKIVLWLEHESGLSDEEDTKAKSLRLAAHLNLAMCHLKLKEYSQALENCNKALELDSSNEKGLFRRGEAHLAVNDFELARGDFQKVIQLYPSNKAAKVQLVTCQQKIREQHEKEKKMYANMFQRLADKELKPATTLQTSHTEDAEMKDEQNGVDDNGFRGAEAELPSHSQEQLCMSVK", "length": 464 }, "evidence": [ { "id": "A0A5G2QVN7", "url": "https://omabrowser.org/oma/group/A0A5G2QVN7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MU79-1", "protein_name": "peptidylprolyl isomerase", "gene_name": "FKBP4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTAEETKAAESGAQSAPLRLEGVDISPKQDEGVLKVIKREGTGMETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDRFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGLAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIRTRGEGYAKPNEGALVEVALEGYFKDQVFDRRELRFEVGEGESMDLPCGLEKAIQRMEKGEHSIVYLKPRYAFGSAGKEKFQIPPNAELKYEIHLKSFEKAKESWEMSSEEKLEQSTIVKERGTVYFKEGKYKQAVLQYKKIVSWLEYESSFSDEDAEKAQALRLASHLNLAMCHLKLQAFSAAIENCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKAQLVVCQQRIRKQLEKEKKLYANMFERLAEEETKAKATVAAGDQPADAEMRDEPKNDVAGGQPQVEAEA", "length": 459 }, "evidence": [ { "id": "A0A5G2QVN7", "url": "https://omabrowser.org/oma/group/A0A5G2QVN7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P30416-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP4", "gene_name": "Fkbp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAEEMKAAENGAQSAPLPLEGVDISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGAAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIRTRGEGYARPNDGAMVEVALEGYHKDRLFDQRELCFEVGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRYEVRLKSFEKAKESWEMSSAEKLEQSNIVKERGTAYFKEGKYKQALLQYKKIVSWLEYESSFSGEEMQKVHALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKTQLAVCQQRTRRQLAREKKLYANMFERLAEEEHKVKAEVAAGDHPTDAEMKGERNNVAENQSRVETEA", "length": 458 }, "evidence": [ { "id": "A0A5G2QVN7", "url": "https://omabrowser.org/oma/group/A0A5G2QVN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q38931-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP62", "gene_name": "FKBP62", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDANFEMPPVGGMNDDDDMDFGDGASFLKVGEEKEIQQGLKKKLLKEGEGYETPENGDEVEVHYTGTLLDGTKFDSSRDRATPFKFTLGQGQVIKGWDIGIKTMKKGENAVFTIPAELAYGESGSPPTIPANATLQFDVELLKWDSVKDICKDGGVFKKILAVGEKWENPKDLDEVLVKFEAKLEDGTVVGKSDGVEFTVKDGHFCPALTKAVKTMKKGEKVLLTVKPQYGFGEKGKPASAGEGAVPPNATLEINLELVSWKTVSEVTDDNKVVKKVLKEGDGYERPNEGAVVKVKLIGKLQDGTVFLKKGHGENEEPFEFKTDEEQVVDGLDRAVMKMKKGEVALVTIDPEYAFGSNESQQELAVVPPNSTVTYEVDLLTFDKERESWDMNTEEKIEAASKKKEEGNSKFKGGKYSLASKRYEKAVKFIEYDTSFSEEEKKQAKALKVACNLNDAACKLKLKDYKQAEKLCTKVLELESTNVKALYRRAQAYMELSDLDLAEFDVKKALEIDPNNREVKLEQKRLKEKMKEFNKKEAKFYGNMFAKLSKE", "length": 551 }, "evidence": [ { "id": "A0A5G2QVN7", "url": "https://omabrowser.org/oma/group/A0A5G2QVN7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q54QI6-1", "protein_name": "peptidylprolyl isomerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSSKRFIPKKETSTSTTTTTTTTSTEITKNIDLNKTEKIQITSDNGITKIINKNGIGNNFPFDGDQIYIKYFGKTIDGTIFEDNRNKSSYSFILGGLGEPIKAFNYAIKSMKKGEISTFTIRSKYAFGAIGNGDSVPPNSTVIYEIELISFSNSSDISIEKDGSIIKKILNNSTTNTTNTNTIGTIPKYEAKISIDFKIKTKELNEIIQDKKNYIFKIGSDIMVLDIIEFILMTMQIGEFCQVEVEWSTFLNSIKKWPLDSLDNNLSYIKKFKDLINSQSQLQQQPIIIEIKLNEIIEFDKEKYQYNLNELESIGLNKKEEGTELFKRKYYEMARLKYKRALAFFNSNDSNSKQHIISCLSNQSVCNLLMKQYKQVIELTTQVLQLDPNHIKSLNSRSKALRETGKLNLAFYDIQKALKIDSHNKDTLNELSILNKLKENKN", "length": 443 }, "evidence": [ { "id": "A0A5G2QVN7", "url": "https://omabrowser.org/oma/group/A0A5G2QVN7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9QVC8-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP4", "gene_name": "Fkbp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAEEMKVAENGAQSAPLPLEGVDISPKQDEGVLKVIKREGTGTETAMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEDEDGGIIRRIRTRGEGYARPNDGAMVEVALEGYYNDRLFDQRELCFEVGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRYEVHLKSFEKAKASWEMNSEEKLEQSNIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSGEEMQKVHALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKTQLAVCQQRTRRQLAREKKLYANMFERLAEEEHKAKTEVAAGDHPTDAEMKGEPNNVAGNQAQVKTEA", "length": 458 }, "evidence": [ { "id": "A0A5G2QVN7", "url": "https://omabrowser.org/oma/group/A0A5G2QVN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VL78-1", "protein_name": "FK506-binding protein 59", "gene_name": "Fkbp59", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPEGNKIDLSGDGGVLKEILKEGTGTETPHSGCTVSLHYTGRLVDGTEFDSSLSRNEPFEFSLGKGNVIKAFDMGVATMKLGERCFLTCAPNYAYGAAGSPPAIPPDATLIFELEMLGWKGEDLSPNQDGSIDRTILEASDKKRTPSDGAFVKAHISGSFEGRVFEDRDVEFDYGEGKAIGIIDGVEIALEKMNVGETSRIKIQAKYAFGAKGNEEFKIPPNATVEYTVKLVDCGKGLEEWKLSDEERLAEAKVYKEKGTNYFKKENWALAIKMYTKCKNILPTTVHTNEEVKKIKVATHSNIALCHQKSNDHFEAKQECNEVLALDKNNVKALYRRGQCNLTINELEDALEDFQKVIQLEPGNKAAANQVIICKQKLKESKNKEKKLYANMFTKLAANDKETEPPRETDVLSKCGEWSEEDAKREAELTLERDNIIMI", "length": 439 }, "evidence": [ { "id": "A0A5G2QVN7", "url": "https://omabrowser.org/oma/group/A0A5G2QVN7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVN7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVN7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVN7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVN7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVN7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] }, { "id": "R-SSC-5324617", "name": "HSP90:FKBP4:PTGES3 binds HSF1 trimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5324617", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5324617" } ] }, { "id": "R-SSC-5618073", "name": "FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-SSC-5618108" ], "output_participant_list": [ "R-SSC-5618096" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5618073", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5618073" } ] }, { "id": "R-SSC-5618080", "name": "HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nuclear envelope, nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5618080", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5618080" } ] }, { "id": "R-SSC-5618085", "name": "FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5618085", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5618085" } ] }, { "id": "R-SSC-5618093", "name": "ATP hydrolysis by HSP90", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-SSC-5324621" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5618093", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5618093" } ] }, { "id": "R-SSC-5618099", "name": "NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5618099", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5618099" } ] }, { "id": "R-SSC-5618110", "name": "p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5618110", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5618110" } ] }, { "id": "R-SSC-8939203", "name": "HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8939203", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939203" } ] }, { "id": "R-SSC-8939204", "name": "ESTG binds ESR1:chaperone complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8939204", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939204" } ] }, { "id": "R-SSC-9032751", "name": "Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-SSC-5082403" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9032751", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9032751" } ] }, { "id": "R-SSC-9038161", "name": "Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9038161", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9038161" } ] }, { "id": "R-SSC-9678925", "name": "NR3C1 binds NR3C1 agonists", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9678925", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9678925" } ] }, { "id": "R-SSC-9690534", "name": "NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9690534", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9690534" } ] }, { "id": "R-SSC-9705925", "name": "Androgens binds AR (in the HSP90 chaperone complex)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9705925", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9705925" } ] }, { "id": "R-SSC-9705926", "name": "AR binds AR agonists", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9705926", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9705926" } ] }, { "id": "R-SSC-9706837", "name": "AR binds AR antagonists", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9706837", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9706837" } ] }, { "id": "R-SSC-9709547", "name": "ESTG binds ESR2:chaperone complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9709547", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9709547" } ] }, { "id": "R-SSC-9716913", "name": "ESR1 binds ESR1 antagonists", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9716913", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9716913" } ] }, { "id": "R-SSC-9716947", "name": "ESR1 binds ESR1 agonists", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9716947", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9716947" } ] }, { "id": "R-SSC-9725855", "name": "NR3C2 binds NR3C2 antagonists", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9725855", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9725855" } ] }, { "id": "R-SSC-9725885", "name": "P4 bind PGR (in the HSP90 chaperone complex)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9725885", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9725885" } ] }, { "id": "R-SSC-9726509", "name": "NR3C2 binds fludrocortisone", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9726509", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9726509" } ] }, { "id": "R-SSC-9726580", "name": "PGR binds PGR agonists", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9726580", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9726580" } ] }, { "id": "R-SSC-9726621", "name": "PGR binds PGR antagonists", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9726621", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9726621" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-5082403", "participant_name": "PTGES3 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000000433", "database": "ENSEMBL", "url": "" }, { "id": "XP_001929448.3", "database": "RefSeq", "url": "" }, { "id": "F1SL99", "database": "UniProt", "url": "" }, { "id": "ENSSSCT00000000439", "database": "ENSEMBL", "url": "" }, { "id": "91952", "database": "VGNC", "url": "" }, { "id": "ENSSSCG00000000406", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-5324621", "participant_name": "FKBP4 [nucleoplasm]", "crossref": [ { "id": "A0A5G2QVN7", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000065998", "database": "ENSEMBL", "url": "" }, { "id": "88147", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000085969", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000000743", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-5618096", "participant_name": "FKBP5 [cytosol]", "crossref": [ { "id": "ENSSSCG00000001549", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000102922", "database": "ENSEMBL", "url": "" }, { "id": "A0A8W4FCG7", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000076958", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-5618108", "participant_name": "FKBP4 [cytosol]", "crossref": [ { "id": "A0A5G2QVN7", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000000743", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000065998", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000085969", "database": "ENSEMBL", "url": "" }, { "id": "88147", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVN7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 455, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVN7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVN7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVN7" }, { "id": "PS50059", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50059" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPIase FKBP-type", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 138, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVP7-1", "uniprot_ac": "A0A5G2QVP7", "uniprot_id": "A0A5G2QVP7_PIG", "mass": { "chemical_mass": 34595.0, "monoisotopic_mass": 34595.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "L1 transposable element RRM domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7", "locus": {} } ], "crossref": [ { "id": "A0A5G2QVP7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000042171", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042171", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QVP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSLTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTARHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKIFPNKQKLKEYSNTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2QVP7-1|A0A5G2QVP7_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QVP7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7/entry#A0A5G2QVP7-1", "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSLTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTARHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKIFPNKQKLKEYSNTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2QVP7-1|A0A5G2QVP7_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QVP7-1" }, "locus": { "chromosome": "3", "start_pos": 65919490, "end_pos": 65918603, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066460.1", "url": "https://www.ensembl.org/id/ENSSSCT00000066460.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068945.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068945.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVP7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 296, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVP7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVP7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 227, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7" }, { "id": "PF17490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element dsRBD-like", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 293, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP7" }, { "id": "PF17489", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element trimerization", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 128, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVP8-1", "uniprot_ac": "A0A5G2QVP8", "uniprot_id": "A0A5G2QVP8_PIG", "mass": { "chemical_mass": 26456.0, "monoisotopic_mass": 26456.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Claudin", "type": "recommended", "evidence": [ { "id": "A0A5G2QVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QVP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050151", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050151", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QVP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDGGPEIHGKCSLPSGPSLAPDAPSSADGSPGSASTSPLFNGRLKLQLMGFVVATVGWVLGTTSMALAEWRVWYVNSTSLLSSHLACVGVWRACIFRQGNGIDRAIGCQGYSYFDPYVPMDIRVAQILLPLATVLGLFSKAAIIFALKSMYLSKVQKTCDASAVAGMLSIAASFCILAAVVWNQLSIQTEEGIAFPPSFNLPFKPDSQEVGGAALMAFLGSCGLFFGGLAYFSYKYPLDSRVHPTTSDT", "length": 250, "header": "tr|A0A5G2QVP8-1|A0A5G2QVP8_PIG Isoform 1 of Claudin OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2QVP8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP8/entry#A0A5G2QVP8-1", "sequence": { "sequence": "MSDGGPEIHGKCSLPSGPSLAPDAPSSADGSPGSASTSPLFNGRLKLQLMGFVVATVGWVLGTTSMALAEWRVWYVNSTSLLSSHLACVGVWRACIFRQGNGIDRAIGCQGYSYFDPYVPMDIRVAQILLPLATVLGLFSKAAIIFALKSMYLSKVQKTCDASAVAGMLSIAASFCILAAVVWNQLSIQTEEGIAFPPSFNLPFKPDSQEVGGAALMAFLGSCGLFFGGLAYFSYKYPLDSRVHPTTSDT", "length": 250, "header": "tr|A0A5G2QVP8-1|A0A5G2QVP8_PIG Isoform 1 of Claudin OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2QVP8-1" }, "locus": { "chromosome": "AEMK02000378.1", "start_pos": 13032, "end_pos": 9798, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074742.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074742.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066008.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066008.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP8" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVP8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 250, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVP8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVP8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVR4-1", "uniprot_ac": "A0A5G2QVR4", "uniprot_id": "A0A5G2QVR4_PIG", "mass": { "chemical_mass": 33853.0, "monoisotopic_mass": 33853.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR4", "locus": {} } ], "crossref": [ { "id": "A0A5G2QVR4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVR4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045014", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045014", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENRNNVTEFVLLGLTQNPEMQKLISAVLFVIYIITMVGNVLIVITITASPSLGSPMYFFLAHLSFIDACYSSVSTPKMIIDSLHGKKTILFEECMTQIFGEHFFGGAEVILLTVMAYDRYVAICKPLHYMTIMNRRVCGLLVGVSWVGGFLHGFIQILFISRLPFCGPNIIDHFMCDLNPLLDLACTDTHTLGLFVAANSGLICLLNFLFLLVSYVVILCSLRTYSLEARHKALSTCISHITVVVLFFVPCIFVYLRPAGTLSIDKAVALFYTTITLMLNPLIYTLRNAQMKNNAMRKVWC", "length": 302, "header": "tr|A0A5G2QVR4-1|A0A5G2QVR4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QVR4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR4/entry#A0A5G2QVR4-1", "sequence": { "sequence": "MENRNNVTEFVLLGLTQNPEMQKLISAVLFVIYIITMVGNVLIVITITASPSLGSPMYFFLAHLSFIDACYSSVSTPKMIIDSLHGKKTILFEECMTQIFGEHFFGGAEVILLTVMAYDRYVAICKPLHYMTIMNRRVCGLLVGVSWVGGFLHGFIQILFISRLPFCGPNIIDHFMCDLNPLLDLACTDTHTLGLFVAANSGLICLLNFLFLLVSYVVILCSLRTYSLEARHKALSTCISHITVVVLFFVPCIFVYLRPAGTLSIDKAVALFYTTITLMLNPLIYTLRNAQMKNNAMRKVWC", "length": 302, "header": "tr|A0A5G2QVR4-1|A0A5G2QVR4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QVR4-1" }, "locus": { "chromosome": "2", "start_pos": 14154524, "end_pos": 14134711, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077480.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077480.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066023.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066023.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVR4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 302, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVR4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVR4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVV2-1", "uniprot_ac": "A0A5G2QVV2", "uniprot_id": "A0A5G2QVV2_PIG", "mass": { "chemical_mass": 54066.0, "monoisotopic_mass": 54066.0 }, "refseq": {}, "gene_names": [ { "name": "EXOC4", "type": "recommended", "evidence": [ { "id": "A0A5G2QVV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2" } ] } ], "protein_names": [ { "name": "Exocyst complex component Sec8", "type": "recommended", "evidence": [ { "id": "A0A5G2QVV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FHC7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHC7#function" }, { "database": "UniProtKB", "id": "RU367079", "url": "https://www.uniprot.org/uniprotkb/RU367079#function" }, { "database": "UniProtKB", "id": "A0A5G2QVV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EXOC4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2", "locus": {} } ], "crossref": [ { "id": "A0A5G2QVV2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVV2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016543", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016543", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14146", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14146", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14146:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14146:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04048", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04048", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QVV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FHC7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FHC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEGAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQQNKEKGRMSSLVKDASPVPLLDVTNLPTPRKFLDTSQYSTPGSSSVKEISLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIKERLEQELKQIVKRSTTQVADSGYQRGENITAENQPRLLLELLELLFDKFNAVATAHSVVLGYLQDTVVTPLTQQEDVKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGE", "length": 475, "header": "tr|A0A5G2QVV2-1|A0A5G2QVV2_PIG Isoform 1 of Exocyst complex component Sec8 OS=Sus scrofa OX=9823 GN=EXOC4 PE=1 SV=1 CANONICAL=A0A5G2QVV2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2/entry#A0A5G2QVV2-1", "sequence": { "sequence": "MAAEGAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQQNKEKGRMSSLVKDASPVPLLDVTNLPTPRKFLDTSQYSTPGSSSVKEISLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIKERLEQELKQIVKRSTTQVADSGYQRGENITAENQPRLLLELLELLFDKFNAVATAHSVVLGYLQDTVVTPLTQQEDVKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGE", "length": 475, "header": "tr|A0A5G2QVV2-1|A0A5G2QVV2_PIG Isoform 1 of Exocyst complex component Sec8 OS=Sus scrofa OX=9823 GN=EXOC4 PE=1 SV=1 CANONICAL=A0A5G2QVV2-1" }, "locus": { "chromosome": "18", "start_pos": 15906668, "end_pos": 15674679, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073550.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073550.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066058.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066058.1" } ] } }, { "isoform_ac": "A0A8W4FHC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2/entry#A0A8W4FHC7-1", "sequence": { "sequence": "MAAEGAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQQNKEKGRMSSLVKDASPVPLLDVTNLPTPRKFLDTSQYSTPGSSSVKEISLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIKERLEQELKQIVKRSTTQVADSGYQRGENITAENQPRLLLELLELLFDKFNAVATAHSVVLGYLQDTVVTPLTQQEDVKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGG", "length": 475, "header": "tr|A0A8W4FHC7-1|A0A5G2QVV2_PIG Computationally mapped isoform of Exocyst complex component Sec8 OS=Sus scrofa OX=9823 GN=EXOC4 PE=1 SV=1 CANONICAL=A0A5G2QVV2-1" }, "locus": { "chromosome": "18", "start_pos": 15906668, "end_pos": 15678778, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103125.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103125.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078642.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078642.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FHC7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHC7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2" } ], "pmid": "" }, { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2" } ], "pmid": "" }, { "name": "vesicle tethering involved in exocytosis", "id": "GO:0090522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090522", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVV2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 475, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVV2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVV2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2" }, { "id": "PF04048", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04048" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exocyst complex component Sec8 N-terminal", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 143, "start_aa": "Gly", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QVV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV2" }, { "id": "PF20652", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20652" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exocyst complex component Sec8 middle helical bundle", "eco_id": "ECO_0000259", "start_pos": 272, "end_pos": 466, "start_aa": "Pro", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 250 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 275, "end_pos": 277 }, { "start_pos": 329, "end_pos": 331 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVV6-1", "uniprot_ac": "A0A5G2QVV6", "uniprot_id": "A0A5G2QVV6_PIG", "mass": { "chemical_mass": 20876.0, "monoisotopic_mass": 20876.0 }, "refseq": { "ac": "XP_003134190", "name": "ganglioside GM2 activator isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134190" }, "gene_names": [ { "name": "GM2A", "type": "recommended", "evidence": [ { "id": "A0A5G2QVV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6" } ] }, { "name": "GM2A", "type": "synonym", "evidence": [ { "id": "XP_003134190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134190" } ] } ], "protein_names": [ { "name": "Ganglioside GM2 activator", "type": "synonym", "evidence": [ { "id": "A0A5G2QVV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6/entry#names_and_taxonomy" } ] }, { "name": "ganglioside GM2 activator isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003134190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134190" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GM2A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6", "locus": { "chromosome": "16", "start_pos": 71742090, "end_pos": 71754884, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017087", "url": "https://www.ensembl.org/id/ENSSSCG00000017087" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017087", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017087", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100515283", "url": "https://www.ncbi.nlm.nih.gov/gene/100515283", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515283", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515283", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WENCGPP", "url": "https://omabrowser.org/oma/group/WENCGPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QVV6", "url": "https://www.orthodb.org/?gene=A0A5G2QVV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17357", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17357", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17357:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17357:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9840310", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003134190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134190", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QVV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0V6", "url": "https://www.uniprot.org/uniprotkb/F1S0V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0V6-1", "url": "https://www.uniprot.org/uniprotkb/F1S0V6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPLMQAPLLIALGLLLTCPAAPALLLPNQLSHFSWENCDGGKDPAVINSLTLKPDPIAIPGNLNVSAEVRTSVLLNDPLKVELTVEKEVAGFWVTIPCVEKMGSCTYDNICDILEVLIPLEDTCPEPLHTYGLPCHCPFKAGTYSLPESEFILPQLELPGWLSSGNYRIQGIMSRNGKHLGCAKISLSLKGK", "length": 193, "header": "tr|A0A5G2QVV6-1|A0A5G2QVV6_PIG Isoform 1 of Ganglioside GM2 activator OS=Sus scrofa OX=9823 GN=GM2A PE=1 SV=1 CANONICAL=A0A5G2QVV6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6/entry#A0A5G2QVV6-1", "sequence": { "sequence": "MSPLMQAPLLIALGLLLTCPAAPALLLPNQLSHFSWENCDGGKDPAVINSLTLKPDPIAIPGNLNVSAEVRTSVLLNDPLKVELTVEKEVAGFWVTIPCVEKMGSCTYDNICDILEVLIPLEDTCPEPLHTYGLPCHCPFKAGTYSLPESEFILPQLELPGWLSSGNYRIQGIMSRNGKHLGCAKISLSLKGK", "length": 193, "header": "tr|A0A5G2QVV6-1|A0A5G2QVV6_PIG Isoform 1 of Ganglioside GM2 activator OS=Sus scrofa OX=9823 GN=GM2A PE=1 SV=1 CANONICAL=A0A5G2QVV6-1" }, "locus": { "chromosome": "16", "start_pos": 71754772, "end_pos": 71743504, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077935.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077935.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069089.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069089.1" } ] } }, { "isoform_ac": "F1S0V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6/entry#F1S0V6-1", "sequence": { "sequence": "MSPLMQAPLLIALGLLLTCPAAPALLLPNQLSHFSWENCDGGKDPAVINSLTLKPDPIAIPGNLNVSAEVELTVEKEVAGFWVTIPCVEKMGSCTYDNICDILEVLIPLEDTCPEPLHTYGLPCHCPFKAGTYSLPESEFILPQLELPGWLSSGNYRIQGIMSRNGKHLGCAKISLSLKGK", "length": 181, "header": "tr|F1S0V6-1|A0A5G2QVV6_PIG Computationally mapped isoform of Ganglioside GM2 activator OS=Sus scrofa OX=9823 GN=GM2A PE=1 SV=3 CANONICAL=A0A5G2QVV6-1" }, "locus": { "chromosome": "16", "start_pos": 71754772, "end_pos": 71743504, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018603.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018603.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018102.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018102.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0V6", "url": "https://www.uniprot.org/uniprotkb/F1S0V6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515283", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515283", "resource": "KEGG Pathway" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A5G9-1", "protein_name": "Ganglioside GM2 activator", "gene_name": "Gm2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLIPLLKRLFSLFIDLYTMYLYCIQSHIPLQSITIFFSFSFFRSWGPNPGPCPSQLGGFSWDNCDEGKDPAVIKSLTLQPDPIVVPGDVIVSAEGKTSIPLTSPQKVELTVEKEVAGFWVKIPCVEQLGSCTYENVCDLIDQYIPPGETCPEPLHTYGLPCHCPFKEGTYSLPSSNFTVPDLELPSWLSTGNYRIQSILSSGGKRLACIKIAASLKGK", "length": 219 }, "evidence": [ { "id": "A0A5G2QVV6", "url": "https://omabrowser.org/oma/group/A0A5G2QVV6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0Z086-1", "protein_name": "Ganglioside GM2 activator", "gene_name": "GM2A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLLAGLFLALCAPSLCPAVLGAARPQLLVERSGPRMLREVGGFSWEDCGNGRDPVVLQSLSVAPDPISIPGNLRISAAVSSSKAMTSPLKAVLVVEKALGDLWIQLPCIDQLGSCTYDDVCNILDNLIPPGMPCPEPLLTYGIPCHCPFKAGSYSLPASDFALPDVELPSWMTNGNYRVRAVVSNKGQELACVKLGFSLQSQ", "length": 202 }, "evidence": [ { "id": "A0A5G2QVV6", "url": "https://omabrowser.org/oma/group/A0A5G2QVV6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P17900-1", "protein_name": "Ganglioside GM2 activator", "gene_name": "GM2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQSLMQAPLLIALGLLLAAPAQAHLKKPSQLSSFSWDNCDEGKDPAVIRSLTLEPDPIIVPGNVTLSVMGSTSVPLSSPLKVDLVLEKEVAGLWIKIPCTDYIGSCTFEHFCDVLDMLIPTGEPCPEPLRTYGLPCHCPFKEGTYSLPKSEFVVPDLELPSWLTTGNYRIESVLSSSGKRLGCIKIAASLKGI", "length": 193 }, "evidence": [ { "id": "A0A5G2QVV6", "url": "https://omabrowser.org/oma/group/A0A5G2QVV6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60648-1", "protein_name": "Ganglioside GM2 activator", "gene_name": "Gm2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLPLLLLLGLLLAGSVAPARLVPKRLSQLGGFSWDNCDEGKDPAVIKSLTIQPDPIVVPGDVVVSLEGKTSVPLTAPQKVELTVEKEVAGFWVKIPCVEQLGSCSYENICDLIDEYIPPGESCPEPLHTYGLPCHCPFKEGTYSLPTSNFTVPDLELPSWLSTGNYRIQSILSSGGKRLGCIKIAASLKGR", "length": 193 }, "evidence": [ { "id": "A0A5G2QVV6", "url": "https://omabrowser.org/oma/group/A0A5G2QVV6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ganglioside catabolic process", "id": "GO:0006689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006689", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6" } ], "pmid": "" }, { "name": "beta-N-acetylhexosaminidase activity", "id": "GO:0004563", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004563", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV6" }, { "id": "SM00737", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00737" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MD-2-related lipid-recognition", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 188, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVW1-1", "uniprot_ac": "A0A5G2QVW1", "uniprot_id": "A0A5G2QVW1_PIG", "mass": { "chemical_mass": 34924.0, "monoisotopic_mass": 34924.0 }, "refseq": { "ac": "XP_003130015", "name": "olfactory receptor 8B3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130015" }, "gene_names": [ { "name": "LOC100525476", "type": "synonym", "evidence": [ { "id": "XP_003130015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130015" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QVW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8B3-like", "type": "synonym", "evidence": [ { "id": "XP_003130015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130015" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1", "locus": {} } ], "crossref": [ { "id": "A0A5G2QVW1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVW1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050744", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050744", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15405", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15405", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100525476", "url": "https://www.ncbi.nlm.nih.gov/gene/100525476", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525476", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525476", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CANTINH", "url": "https://omabrowser.org/oma/group/CANTINH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QVW1", "url": "https://www.orthodb.org/?gene=A0A5G2QVW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003130015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130015", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QVW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPGNGSFVTDFILVGLTDHPALQLPLFLLFLAMYMVTVLGNFGLITVIGLNSHLHTPMYFFLLNLSFIDLCYSSVFTPEMLTHFLSEKKIISYLGCMTQLFFFGFLILSECYVLTAMAYDRYVAICNPLLYNIAMSPKVCSSLMLACYLMALSGAMAHTGCMLRLTFCDANTINHYFCDILPLLQLSCTSTYINEIVLFIASCINIIVPSLTIFVSYGLILSNILRISSMESRSKAFSTCSSHIIAISLFFASGEIMYLQPSSSGSMDKGKISSVFYTNVVPMMNPLIYSLRNKDVKFALRKTLRRRFWF", "length": 311, "header": "tr|A0A5G2QVW1-1|A0A5G2QVW1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QVW1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1/entry#A0A5G2QVW1-1", "sequence": { "sequence": "MAPGNGSFVTDFILVGLTDHPALQLPLFLLFLAMYMVTVLGNFGLITVIGLNSHLHTPMYFFLLNLSFIDLCYSSVFTPEMLTHFLSEKKIISYLGCMTQLFFFGFLILSECYVLTAMAYDRYVAICNPLLYNIAMSPKVCSSLMLACYLMALSGAMAHTGCMLRLTFCDANTINHYFCDILPLLQLSCTSTYINEIVLFIASCINIIVPSLTIFVSYGLILSNILRISSMESRSKAFSTCSSHIIAISLFFASGEIMYLQPSSSGSMDKGKISSVFYTNVVPMMNPLIYSLRNKDVKFALRKTLRRRFWF", "length": 311, "header": "tr|A0A5G2QVW1-1|A0A5G2QVW1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QVW1-1" }, "locus": { "chromosome": "9", "start_pos": 50799160, "end_pos": 50798228, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089277.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089277.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069094.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069094.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525476", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525476", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVW1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVW1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVW1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVW1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVZ0-1", "uniprot_ac": "A0A5G2QVZ0", "uniprot_id": "A0A5G2QVZ0_PIG", "mass": { "chemical_mass": 33003.0, "monoisotopic_mass": 33003.0 }, "refseq": { "ac": "XP_003127375", "name": "nitric oxide synthase-interacting protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003127375" }, "gene_names": [ { "name": "NOSIP", "type": "recommended", "evidence": [ { "id": "A0A5G2QVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0" } ] }, { "name": "NOSIP", "type": "synonym", "evidence": [ { "id": "XP_003127375", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003127375" } ] } ], "protein_names": [ { "name": "Nitric oxide synthase-interacting protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0/entry#names_and_taxonomy" } ] }, { "name": "nitric oxide synthase-interacting protein", "type": "synonym", "evidence": [ { "id": "XP_003127375", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003127375" } ] } ], "function": [ { "annotation": "Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0#function" }, { "database": "UniProtKB", "id": "PIRNR023577", "url": "https://www.uniprot.org/uniprotkb/PIRNR023577#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NOSIP", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0", "locus": { "chromosome": "6", "start_pos": 54617782, "end_pos": 54635942, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000029154", "url": "https://www.ensembl.org/id/ENSSSCG00000029154" } ] } } ], "crossref": [ { "id": "A0A5G2QVZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000029154", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000029154", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16662", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16662", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100518311", "url": "https://www.ncbi.nlm.nih.gov/gene/100518311", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518311", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518311", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PCVTKFM", "url": "https://omabrowser.org/oma/group/PCVTKFM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QVZ0", "url": "https://www.orthodb.org/?gene=A0A5G2QVZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13063:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13063:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-203754", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-203754", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003127375", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003127375", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RHW0", "url": "https://www.uniprot.org/uniprotkb/F1RHW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RHW0-1", "url": "https://www.uniprot.org/uniprotkb/F1RHW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRHGKNCTAGAVYTYHEKKKDTAASGYGTQNIRLSRDAVKDFDCCCLSLQPCHDPVVTPDGYLYEREAILEYILHQKKEIARQMKAYEKQRGARREEQKELQRAAAQDQVRGFLEKEAAIVSRPLNPFTPKAASGDSPDDAQPGPSAGPAGKDKDKALPSFWIPSLTPEAKATKLEKPSRVVTCPMSGKPLRMSDLTPVRFTPLDSSVDRVGLITRSERYVCAVTRDSLSNATPCAVLRPSGAVVTLECVEKLIRKDMVDPVNGEKLTDRDIIVLQRGGTGFAGSGVKLQAEKSRPVMQA", "length": 301, "header": "tr|A0A5G2QVZ0-1|A0A5G2QVZ0_PIG Isoform 1 of Nitric oxide synthase-interacting protein OS=Sus scrofa OX=9823 GN=NOSIP PE=1 SV=1 CANONICAL=A0A5G2QVZ0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0/entry#A0A5G2QVZ0-1", "sequence": { "sequence": "MTRHGKNCTAGAVYTYHEKKKDTAASGYGTQNIRLSRDAVKDFDCCCLSLQPCHDPVVTPDGYLYEREAILEYILHQKKEIARQMKAYEKQRGARREEQKELQRAAAQDQVRGFLEKEAAIVSRPLNPFTPKAASGDSPDDAQPGPSAGPAGKDKDKALPSFWIPSLTPEAKATKLEKPSRVVTCPMSGKPLRMSDLTPVRFTPLDSSVDRVGLITRSERYVCAVTRDSLSNATPCAVLRPSGAVVTLECVEKLIRKDMVDPVNGEKLTDRDIIVLQRGGTGFAGSGVKLQAEKSRPVMQA", "length": 301, "header": "tr|A0A5G2QVZ0-1|A0A5G2QVZ0_PIG Isoform 1 of Nitric oxide synthase-interacting protein OS=Sus scrofa OX=9823 GN=NOSIP PE=1 SV=1 CANONICAL=A0A5G2QVZ0-1" }, "locus": { "chromosome": "6", "start_pos": 54624236, "end_pos": 54619663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084757.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084757.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062354.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062354.1" } ] } }, { "isoform_ac": "F1RHW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0/entry#F1RHW0-1", "sequence": { "sequence": "MQSRTLTAAASLCSPATTPSSRHSKGLAVPSQEPGRGQSLGGKVQGVDKPGLLRSPFTARDFSYTSEHVTKPGKEFPGGLAVEDSAWSLLWPSPDGYLYEREAILEYILHQKKEIARQMKAYEKQRGARREEQKELQRAAAQDQVRGFLEKEAAIVSRPLNPFTPKAASGDSPDDAQPGPSAGPAGKDKDKALPSFWIPSLTPEAKATKLEKPSRVVTCPMSGKPLRMSDLTPVRFTPLDSSVDRVGLITRSERYVCAVTRDSLSNATPCAVLRPSGAVVTLECVEKLIRKDMVDPVNGEKLTDRDIIVLQRGGTGFAGSGVKLQAEKSRPVMQA", "length": 335, "header": "tr|F1RHW0-1|A0A5G2QVZ0_PIG Computationally mapped isoform of Nitric oxide synthase-interacting protein OS=Sus scrofa OX=9823 GN=NOSIP PE=1 SV=2 CANONICAL=A0A5G2QVZ0-1" }, "locus": { "chromosome": "6", "start_pos": 54623563, "end_pos": 54619663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031851.3", "url": "https://www.ensembl.org/id/ENSSSCT00000031851.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021692.2", "url": "https://www.ensembl.org/id/ENSSSCP00000021692.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RHW0", "url": "https://www.uniprot.org/uniprotkb/F1RHW0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518311", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518311", "resource": "KEGG Pathway" }, { "id": "R-SSC-203754", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-203754", "resource": "Reactome", "description": "NOSIP mediated eNOS trafficking" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZH12-1", "protein_name": "Nitric oxide synthase-interacting protein", "gene_name": "Nosip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRHGKNCTAGAVYTYHEKKKDTAASGYGTQNIRLSRDAVKDFDCCCLSLQPCHDPVVTPDGYLYEREAILEYILHQKREIARQMKAYEKQRGARREEQKELQRAAAQDQVRGFLEKESAIVSRPLNPFMPKAATLPNTDGEQPGPSVGPLGKDKDKALPSFWIPSLTPEAKATKLEKPSRTVTCPMSGKPLRMSDLTSVRFTQLDDSVDRVGLITRSERYVCAVTRDSLSNATPCAVLRPSGAVVTLECVEKLIRKDMVDPVNGDTLTERDIIVLQRGGTGFAGSGVKLQAEMSRPVMQA", "length": 301 }, "evidence": [ { "id": "A0A5G2QVZ0", "url": "https://omabrowser.org/oma/group/A0A5G2QVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3ILN4-1", "protein_name": "Nitric oxide synthase-interacting protein", "gene_name": "Nosip", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTRHGKNCTAGAVYTYHEKKKDTAASGYGTQNIRLSRDAVKDFDCCCLSLQPCHDPVVTPDGYLYEREAILEYILHQKKEIARQMKAYEKQRGARREEQKQLQRAAAQDQVRGFLEKEAAIVSRPLNPFMPKAAPLPNTDGEQPGPSSGPPGKDKDKALPSFWIPSLTPEAKATKLEKPSRTVTCPMSGKPLRMSDLTPVRFTQLDDSVDRVGLITRSERYVCAVTRDSLSNATPCAVLRPSGAVVTLECVEKLIRKDMVDPVNGDTLTERDIIVLQRGGTGFAGSGVKLQAEMSRPVMQA", "length": 301 }, "evidence": [ { "id": "A0A5G2QVZ0", "url": "https://omabrowser.org/oma/group/A0A5G2QVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3SWY5-1", "protein_name": "Nitric oxide synthase-interacting protein", "gene_name": "NOSIP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTRHGKNCTAGAVYTYHEKKKDTAASGYGTQNIRLSRDAVKDFDCCCLSLQPCHDPVVTPDGYLYEREAILEYILHQKKEIARQMKAYEKQRGARREEQKELQRAAAQDHVRGFLEKEAAIVSRPLNPFTPKAASAGNGPDDAQPGSSAGPAGKDKDKALPSFWIPSLTPEAKATKLEKPSRIVTCPMSGKPLRMSDLTPVRFTPLDSSVDRVGLITRSERYVCAVTRDSLSNATPCAVLRPSGAVVTLECVEKLIRKDMVDPVTGEKLTDRDIIVLQRGGTGFAGSGVKLQAEKSRPVMQA", "length": 302 }, "evidence": [ { "id": "A0A5G2QVZ0", "url": "https://omabrowser.org/oma/group/A0A5G2QVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55DU4-1", "protein_name": "Nitric oxide synthase-interacting protein homolog", "gene_name": "nosip", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRHSKHSCSNSGKFSNYERQLLKYGTTTERLGKDSIKNFDSCSLCLNDVIMPVICNKGHLYCKECILTSLIDQKKLIKIKEKEWEQYQNKLKYEQDQKQEKQHQDSIKEFEKNVITLEGIGSNDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTTTSDVNNKDKEKKEIVEKEIKLNSYWVITPDNKDKAIEKPRSYTVCPADGKHPLKSAQLINVHFTNVKPSSSDSNDSNNQYCCPICSKVLSNSTKTRLLKRCGHVFCSCLDKFKEDSSSQLSCYVCDKPYTEDEIIQIHSGGTGFSGSGSNLEAKKYTHTAIV", "length": 333 }, "evidence": [ { "id": "A0A5G2QVZ0", "url": "https://omabrowser.org/oma/group/A0A5G2QVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5U3S7-1", "protein_name": "Nitric oxide synthase-interacting protein", "gene_name": "nosip", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTRHGKNCTAGAVYTYHEKRKDTAASGYGTQSVRLGKDAIKDFDCCSLSLQPCRDPVLTEDGYLYEKEAILQYILHQKTEIAKKMKAYEKQKQALKSEGQLESKSEERERAEKFKQRENNIVSKPINPFTSGKSKDEGNQNGSTSSSSTDTSSGESSSSSALPSFWIPSLTPEAKPTLLKKPSKTVSCPMSGRPLKMSDLITVRFTPLDPSLDRVALLTRQDRYVCAVTKDTLGNSVPCAVLRPSGVVVTMECVEKLIKKDMVDPITGDKLKEKDIIPIQRGGTGFAGSGVDLKAKEARPVMQA", "length": 304 }, "evidence": [ { "id": "A0A5G2QVZ0", "url": "https://omabrowser.org/oma/group/A0A5G2QVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D6T0-1", "protein_name": "Nitric oxide synthase-interacting protein", "gene_name": "Nosip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRHGKNCTAGAVYTYHEKKKDTAASGYGTQNIRLSRDAVKDFDCCCLSLQPCHDPVVTPDGYLYEREAILEYILHQKREIARQVKAYEKQRGARREEQKELQRAAAQDQVRGFLEKEAAIVSRPLNPFMPKAATLPNTEGEQPGPSVGPVGKDKDKALPSFWIPSLTPEAKATKLEKPSRTVTCPMSGKPLRMSDLTSVRFTQLDDSVDRVGLITRSERYVCAVTRDSLSNATPCAVLRPSGAVVTLECVEKLIRKDMVDPVNGDTLTERDIIVLQRGGTGFAGSGVKLQAEMSRPVMQA", "length": 301 }, "evidence": [ { "id": "A0A5G2QVZ0", "url": "https://omabrowser.org/oma/group/A0A5G2QVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SY88-1", "protein_name": "E3 ubiquitin-protein ligase CSU1", "gene_name": "CSU1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPQRHSKNNNDLAYFTYDEKKKLGYGTQRERLGRDSIKPFDACSLCLKPFIDPMCCHKGHVFCRECILECFLAQKKDIQRRLAAHSSQKKQDKDEEEERLMLQKARELDEFDQQNHSAMPRNSDKNHNEDKNGFHGANSVKTTSFEEEALRTMKAFWLPSATPAASVRVDAPETHTVCPEGKEKLKLKNLFAIRFTEDNSEEEETKTKSASSSSYDKSYICPSCKVTLTNTMSLVALSSCGHVFCKKCAEKFMPVDKVCLVCDKPCKDRNLVGLKKGGTGFAEHDDHLEAKEYKHLGSGSGLGLVRPVKT", "length": 310 }, "evidence": [ { "id": "A0A5G2QVZ0", "url": "https://omabrowser.org/oma/group/A0A5G2QVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VWV8-1", "protein_name": "Nitric oxide synthase-interacting protein homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTRHARNCTAGAVYTYNEKKRDAAESGYGTNAQRLGKDSVKSFDCCSLTLQPCRRPVITKDGYLFDKEAILQYIVTKKNEYSRRLKEYERLRRAEEDKLSQEANSKQQARMERFVNAEKPAMTPAHSSAAASEKPSTSSAAAAASSESSSASSISNMTNGHEKKLPSFWLPSECPNAGLAKAQKPDATIYCPVSQKPLRVKDLIDVKFTLLKDGDTKRSLIAKEARYMCPITHDVLSNAVPCAVLRPTGDVVTMECVERLIRKDMIHPLTDRKLKEKDIIPLQRGGTGYATTNDHLQAKEKRPMLQA", "length": 307 }, "evidence": [ { "id": "A0A5G2QVZ0", "url": "https://omabrowser.org/oma/group/A0A5G2QVZ0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y314-1", "protein_name": "Nitric oxide synthase-interacting protein", "gene_name": "NOSIP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTRHGKNCTAGAVYTYHEKKKDTAASGYGTQNIRLSRDAVKDFDCCCLSLQPCHDPVVTPDGYLYEREAILEYILHQKKEIARQMKAYEKQRGTRREEQKELQRAASQDHVRGFLEKESAIVSRPLNPFTAKALSGTSPDDVQPGPSVGPPSKDKDKVLPSFWIPSLTPEAKATKLEKPSRTVTCPMSGKPLRMSDLTPVHFTPLDSSVDRVGLITRSERYVCAVTRDSLSNATPCAVLRPSGAVVTLECVEKLIRKDMVDPVTGDKLTDRDIIVLQRGGTGFAGSGVKLQAEKSRPVMQA", "length": 301 }, "evidence": [ { "id": "A0A5G2QVZ0", "url": "https://omabrowser.org/oma/group/A0A5G2QVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0" } ], "pmid": "" }, { "name": "molecular sequestering activity", "id": "GO:0140313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140313", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of nitric oxide biosynthetic process", "id": "GO:0045428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045428", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVZ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 301, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVZ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVZ0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ0" }, { "id": "PF15906", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15906" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nitric oxide synthase-interacting protein zinc-finger", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 78, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QVZ7-1", "uniprot_ac": "A0A5G2QVZ7", "uniprot_id": "A0A5G2QVZ7_PIG", "mass": { "chemical_mass": 50448.0, "monoisotopic_mass": 50448.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Tripartite motif-containing protein 64-like", "type": "recommended", "evidence": [ { "id": "A0A5G2QVZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7", "locus": {} } ], "crossref": [ { "id": "A0A5G2QVZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19783", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19783", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SICMNYY", "url": "https://omabrowser.org/oma/group/SICMNYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QVZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6B7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STP4", "url": "https://www.uniprot.org/uniprotkb/F1STP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STP4-1", "url": "https://www.uniprot.org/uniprotkb/F1STP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSEGFMHTFQDELKCSICMNYFIDPVTTDCGHSFCRPCLYLCWEEEQAPKSCPECRAVSEKPDFKTNIVLKRLASLARQARASHSSRSEEQLCGTHREAKGLFCEADKTLLCGPCSEGPEHAAHSHSPIQWAAEERREMLLKRMDSLWKMTQEMQNNRNQETKKIRSLEDYVTLRKVMIKLQYQRMHLFLREEEQFHLEALEKEAKETGRDLKESVFRMTQQKETLKEMYSMLTELCRSPDTELLQVRRGTELVQMQNPQPVNPELTCWPVTGMLEMLNNFRVIPLALHQRASLDSLLSFPFSLPWRREKGKTHWGESPCLPLRIFVAWGAQAFTSGRHYWEVDVTRSSNWILGVCKDIWTSDTDIINDQYTLSTNSPPLIQYVQRPLGRVGVFLDYDNGTVSFYDVCKGSLIYSFLPSSFSSPLRPYLFFSSP", "length": 435, "header": "tr|A0A5G2QVZ7-1|A0A5G2QVZ7_PIG Isoform 1 of Tripartite motif-containing protein 64-like OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QVZ7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7/entry#A0A5G2QVZ7-1", "sequence": { "sequence": "MDSEGFMHTFQDELKCSICMNYFIDPVTTDCGHSFCRPCLYLCWEEEQAPKSCPECRAVSEKPDFKTNIVLKRLASLARQARASHSSRSEEQLCGTHREAKGLFCEADKTLLCGPCSEGPEHAAHSHSPIQWAAEERREMLLKRMDSLWKMTQEMQNNRNQETKKIRSLEDYVTLRKVMIKLQYQRMHLFLREEEQFHLEALEKEAKETGRDLKESVFRMTQQKETLKEMYSMLTELCRSPDTELLQVRRGTELVQMQNPQPVNPELTCWPVTGMLEMLNNFRVIPLALHQRASLDSLLSFPFSLPWRREKGKTHWGESPCLPLRIFVAWGAQAFTSGRHYWEVDVTRSSNWILGVCKDIWTSDTDIINDQYTLSTNSPPLIQYVQRPLGRVGVFLDYDNGTVSFYDVCKGSLIYSFLPSSFSSPLRPYLFFSSP", "length": 435, "header": "tr|A0A5G2QVZ7-1|A0A5G2QVZ7_PIG Isoform 1 of Tripartite motif-containing protein 64-like OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QVZ7-1" }, "locus": { "chromosome": "9", "start_pos": 23015284, "end_pos": 23009082, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083677.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083677.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069046.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069046.1" } ] } }, { "isoform_ac": "A0A5G2R6B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7/entry#A0A5G2R6B7-1", "sequence": { "sequence": "MDSEGFMHTFQDELKCSICMNYFIDPVTTDCGHSFCRPCLYLCWEEEQAPKSCPECRAVSEKPDFKTNIVLKRLASLARQARASHSSRSEEQLCGTHREAKGLFCEADKTLLCGPCSEGPEHAAHSHSPIQWAAEERREMLLKRMDSLWKMTQEMQNNRNQETKKIRSLEVRKSMKVMIKLQYQRMHLFLREEEQFHLEALEKEAKETGRDLKESVFRMTQQKETLKEMYSMLTELCRSPDTELLQVRRGTELVQMQNPQPVNPELTCWPVTGMLEMLNNFRGDPIYTHNSKVVVFEDDPQGASSEPPSEERFVAWGAQAFTSGRHYWEVDVTRSSNWILGVCKDIWTSDTDIINDQYTLSTNSPPLIQYVQRPLGRVGVFLDYDNGTVSFYDVCKGSLIYSFLPSSFSSPLRPYLFFSSP", "length": 421, "header": "tr|A0A5G2R6B7-1|A0A5G2QVZ7_PIG Computationally mapped isoform of Tripartite motif-containing protein 64-like OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QVZ7-1" }, "locus": { "chromosome": "9", "start_pos": 23015284, "end_pos": 23009082, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069241.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069241.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066135.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066135.1" } ] } }, { "isoform_ac": "F1STP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7/entry#F1STP4-1", "sequence": { "sequence": "MDSEGFMHTFQDELKCSICMNYFIDPVTTDCGHSFCRPCLYLCWEEEQAPKSCPECRAVSEKPDFKTNIVLKRLASLARQARASHSSRSEEQLCGTHREAKGLFCEADKTLLCGPCSEGPEHAAHSHSPIQWAAEERREMLLKRMDSLWKMTQEMQNNRNQETKKIRSLEDYVTLRKVMIKLQYQRMHLFLREEEQFHLEALEKEAKETGRDLKESVFRMTQQKETLKEMYSMLTELCRSPDTELLQVRRGTELVQMQNPQPVNPELTCWPVTGMLEMLNNFRAENVLSQKMSIHSVRLSEDEASVVFEDDPQGASSEPPSEERFVAWGAQAFTSGRHYWEVDVTRSSNWILGVCKDIWTSDTDIINDQYTLSTNSPPLIQYVQRPLGRVGVFLDYDNGTVSFYDVCKGSLIYSFLPSSFSSPLRPYLFFSSP", "length": 433, "header": "tr|F1STP4-1|A0A5G2QVZ7_PIG Computationally mapped isoform of Tripartite motif-containing protein 64-like OS=Sus scrofa OX=9823 GN= PE=4 SV=3 CANONICAL=A0A5G2QVZ7-1" }, "locus": { "chromosome": "9", "start_pos": 23015284, "end_pos": 23009082, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016288.3", "url": "https://www.ensembl.org/id/ENSSSCT00000016288.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015852.3", "url": "https://www.ensembl.org/id/ENSSSCP00000015852.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1STP4", "url": "https://www.uniprot.org/uniprotkb/F1STP4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QVZ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 435, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QVZ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QVZ7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QVZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 130, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QVZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 241, "end_pos": 435, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QVZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVZ7" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 57, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 400, "end_pos": 402 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QW27-1", "uniprot_ac": "A0A5G2QW27", "uniprot_id": "A0A5G2QW27_PIG", "mass": { "chemical_mass": 35079.0, "monoisotopic_mass": 35079.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QW27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW27/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW27#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW27" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW27", "locus": {} } ], "crossref": [ { "id": "A0A5G2QW27", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QW27", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QW27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW27-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGNYTSATEFYLLGFPGSQDLRHVLFATFLLLYSVTLMGNTVIIALVCVDKRLQSPMYFFLGHLSALEILVTSILVPVMLWGLLLPGMQTVSLPGCVAQLFLYLAVGTTEFALLGGMAVDRDVAVCNPLRYHIIMNSRTCNFVVIGSWAFGFLFQIWPVYATFQLSYCKSNVVNNFFCDRGQLLKLSCSNTLFMEFILFLMAVFVLFGSLIPTIVSYSYIVSTVLRIPSASGWRKACSTCASHFTCVVIGYGSCLFLYVKPKQTQASDYNRVVSLMVSVVTPFLNPFIFTLRNDKVLEALRDGGKRCCHPFRN", "length": 314, "header": "tr|A0A5G2QW27-1|A0A5G2QW27_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QW27-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QW27-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW27/entry#A0A5G2QW27-1", "sequence": { "sequence": "MLGNYTSATEFYLLGFPGSQDLRHVLFATFLLLYSVTLMGNTVIIALVCVDKRLQSPMYFFLGHLSALEILVTSILVPVMLWGLLLPGMQTVSLPGCVAQLFLYLAVGTTEFALLGGMAVDRDVAVCNPLRYHIIMNSRTCNFVVIGSWAFGFLFQIWPVYATFQLSYCKSNVVNNFFCDRGQLLKLSCSNTLFMEFILFLMAVFVLFGSLIPTIVSYSYIVSTVLRIPSASGWRKACSTCASHFTCVVIGYGSCLFLYVKPKQTQASDYNRVVSLMVSVVTPFLNPFIFTLRNDKVLEALRDGGKRCCHPFRN", "length": 314, "header": "tr|A0A5G2QW27-1|A0A5G2QW27_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QW27-1" }, "locus": { "chromosome": "18", "start_pos": 8062448, "end_pos": 8046415, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028796.3", "url": "https://www.ensembl.org/id/ENSSSCT00000028796.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069076.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069076.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW27" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW27" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW27" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QW27-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QW27-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QW27" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QW27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW27" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 290, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QW52-1", "uniprot_ac": "A0A5G2QW52", "uniprot_id": "A0A5G2QW52_PIG", "mass": { "chemical_mass": 75437.0, "monoisotopic_mass": 75437.0 }, "refseq": {}, "gene_names": [ { "name": "SAMD4B", "type": "recommended", "evidence": [ { "id": "A0A5G2QW52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52" } ] } ], "protein_names": [ { "name": "Sterile alpha motif domain containing 4B", "type": "synonym", "evidence": [ { "id": "A0A5G2QW52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW52", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SAMD4B", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52", "locus": { "chromosome": "6", "start_pos": 48046555, "end_pos": 48002712, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010706", "url": "https://www.ensembl.org/id/ENSSSCG00000010706" } ] } } ], "crossref": [ { "id": "A0A5G2QW52", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QW52", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010706", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010706", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09557", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09557", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12515:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12515:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QW52", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW52-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GPV1", "url": "https://www.uniprot.org/uniprotkb/K7GPV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GPV1-1", "url": "https://www.uniprot.org/uniprotkb/K7GPV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLESEANSAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEESRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRTRPEPSYHSRQGSDEWGGPAELGPGEAGPGWQDKPPRENGHVPFHPPSSVPPAINSIGSNANAGLPCQIHPSPLKRSMSLIPTSPQAPGEWPSPEELVARATFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQEDGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAGATTTPPAKDGGRGEPPLPGAESPLAHPGTDKGSEAKDPPAAESFPPPPAPASTDGSEPAPAPVADGDIPSQFTRVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAALEMQNYRQQKGWAFGSNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGISPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFPPDCPVPGPDLEINPTLESLCLSMTEHALGGEHFLFP", "length": 693, "header": "tr|A0A5G2QW52-1|A0A5G2QW52_PIG Isoform 1 of Sterile alpha motif domain containing 4B OS=Sus scrofa OX=9823 GN=SAMD4B PE=1 SV=1 CANONICAL=A0A5G2QW52-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QW52-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52/entry#A0A5G2QW52-1", "sequence": { "sequence": "MMFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLESEANSAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEESRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRTRPEPSYHSRQGSDEWGGPAELGPGEAGPGWQDKPPRENGHVPFHPPSSVPPAINSIGSNANAGLPCQIHPSPLKRSMSLIPTSPQAPGEWPSPEELVARATFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQEDGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAGATTTPPAKDGGRGEPPLPGAESPLAHPGTDKGSEAKDPPAAESFPPPPAPASTDGSEPAPAPVADGDIPSQFTRVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAALEMQNYRQQKGWAFGSNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGISPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFPPDCPVPGPDLEINPTLESLCLSMTEHALGGEHFLFP", "length": 693, "header": "tr|A0A5G2QW52-1|A0A5G2QW52_PIG Isoform 1 of Sterile alpha motif domain containing 4B OS=Sus scrofa OX=9823 GN=SAMD4B PE=1 SV=1 CANONICAL=A0A5G2QW52-1" }, "locus": { "chromosome": "6", "start_pos": 48044144, "end_pos": 48019398, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072934.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072934.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069179.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069179.1" } ] } }, { "isoform_ac": "K7GPV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52/entry#K7GPV1-1", "sequence": { "sequence": "MSGDLEQEALRKRLRIVSRNQSVEEGLLSAQLTQLLCSSCLRGGFGCFLAWEFLTLMSSLLLRLEPGEVWLDQDLSRCEQVSSPHHPLPPRQGTSSSPGPQGRGNQSPEPRPCDGAGPCHRRPPHPGPRPGTMMFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLESEANSAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEESRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRTRPEPSYHSRQGSDEWGGPAELGPGEAGPGWQDKPPRENGHVPFHPPSSVPPAINSIGSNANAGLPCQIHPSPLKRSMSLIPTSPQAPGEWPSPEELVARATFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQEDGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAGATTTPPAKDGGRGEPPLPGAESPLAHPGTDKGSEAKDPPAAESFPPPPAPASTDGSEPAPAPVADGDIPSQFTRVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAALEMQNYRQQKGWAFGSNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGISPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFPPDCPVPGPDLEINPTLESLCLSMTEHALGDGTDKTSTI", "length": 827, "header": "tr|K7GPV1-1|A0A5G2QW52_PIG Computationally mapped isoform of Sterile alpha motif domain containing 4B OS=Sus scrofa OX=9823 GN=SAMD4B PE=1 SV=3 CANONICAL=A0A5G2QW52-1" }, "locus": { "chromosome": "6", "start_pos": 48044352, "end_pos": 48018190, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033498.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033498.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029917.3", "url": "https://www.ensembl.org/id/ENSSSCP00000029917.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "K7GPV1", "url": "https://www.uniprot.org/uniprotkb/K7GPV1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW52", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52" } ], "pmid": "" }, { "name": "translation repressor activity", "id": "GO:0030371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030371", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW52", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW52", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW52", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW52", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0000289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000289", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW52", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52" } ], "pmid": "" }, { "name": "regulation of mRNA stability", "id": "GO:0043488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043488", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW52", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QW52-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 693, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QW52-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QW52" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QW52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW52" }, { "id": "SM00454", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00454" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 359, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 340, "end_pos": 342 }, { "start_pos": 496, "end_pos": 498 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QW67-1", "uniprot_ac": "A0A5G2QW67", "uniprot_id": "A0A5G2QW67_PIG", "mass": { "chemical_mass": 35574.0, "monoisotopic_mass": 35574.0 }, "refseq": { "ac": "XP_003130011", "name": "olfactory receptor 6M1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130011" }, "gene_names": [ { "name": "LOC100524576", "type": "synonym", "evidence": [ { "id": "XP_003130011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130011" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QW67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW67/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6M1-like", "type": "synonym", "evidence": [ { "id": "XP_003130011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130011" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW67#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW67" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW67", "locus": {} } ], "crossref": [ { "id": "A0A5G2QW67", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QW67", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000049437", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000049437", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524576", "url": "https://www.ncbi.nlm.nih.gov/gene/100524576", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524576", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524576", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LPYCYRE", "url": "https://omabrowser.org/oma/group/LPYCYRE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QW67", "url": "https://www.orthodb.org/?gene=A0A5G2QW67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003130011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130011", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QW67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW67-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVQNQTTVTEFILTAFPALHKLQVFLFAVLLVTYMLTLTGNGVIISLIWADNRLQIPMYFFLSNLSFLDILYTTSVTPKLLACLLEDRKSISFAGCITQTYFFFFLGTVEFILLAVMSFDRYVAICNPLRYTIIMNSRVCLLLVLGCWVGAFLSVLCPTIVVSRLPFCSKEISHFFCDIAPLLQVACIDTHFIEMINFLLSSLVLLTSLVLTTVSYTYIISTILRIPSAQGRQKAFSTCASHITVVSIAYGSNIFMYVRPSQSHSLEFDKVTAVLTTMGTPLLNPFIYSLRNEKVKEVLRDAVNQIMSPWHRKP", "length": 315, "header": "tr|A0A5G2QW67-1|A0A5G2QW67_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QW67-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QW67-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW67/entry#A0A5G2QW67-1", "sequence": { "sequence": "MEVQNQTTVTEFILTAFPALHKLQVFLFAVLLVTYMLTLTGNGVIISLIWADNRLQIPMYFFLSNLSFLDILYTTSVTPKLLACLLEDRKSISFAGCITQTYFFFFLGTVEFILLAVMSFDRYVAICNPLRYTIIMNSRVCLLLVLGCWVGAFLSVLCPTIVVSRLPFCSKEISHFFCDIAPLLQVACIDTHFIEMINFLLSSLVLLTSLVLTTVSYTYIISTILRIPSAQGRQKAFSTCASHITVVSIAYGSNIFMYVRPSQSHSLEFDKVTAVLTTMGTPLLNPFIYSLRNEKVKEVLRDAVNQIMSPWHRKP", "length": 315, "header": "tr|A0A5G2QW67-1|A0A5G2QW67_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QW67-1" }, "locus": { "chromosome": "9", "start_pos": 50680644, "end_pos": 50679700, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083795.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083795.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066173.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066173.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW67" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524576", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524576", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW67" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW67" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QW67-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 315, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QW67-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QW67" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QW67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW67" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QW81-1", "uniprot_ac": "A0A5G2QW81", "uniprot_id": "A0A5G2QW81_PIG", "mass": { "chemical_mass": 36515.0, "monoisotopic_mass": 36515.0 }, "refseq": { "ac": "XP_020917892", "name": "olfactory receptor 51G1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020917892" }, "gene_names": [ { "name": "LOC110255340", "type": "synonym", "evidence": [ { "id": "XP_020917892", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020917892" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QW81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 51G1-like", "type": "synonym", "evidence": [ { "id": "XP_020917892", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020917892" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81", "locus": {} } ], "crossref": [ { "id": "A0A5G2QW81", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QW81", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000042716", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042716", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15222", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15222", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110255340", "url": "https://www.ncbi.nlm.nih.gov/gene/110255340", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110255340", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255340", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QW81", "url": "https://www.orthodb.org/?gene=A0A5G2QW81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF94", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF94", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020917892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020917892", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QW81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW81-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPWASLVTAPGSNASSGPPASFYLTGIPGSENVQPFLSLPFCVLYLTGTVGNCTILHIIHTDQRLHEPMYYFLAMLALTDLGMSISTLPTVLKTFWFDAKEIEINACVAQMYFIHTFSLMESAVLLAMALDRYVAICDPLRYCSKLTPRRIVYIGGFIVIRCSPVLPVILVRIPRLSFCHSHVLSHSFCLHQDIIRLACADISFNVLFGLFVVVFYWGVDALGIFLSYAFIFRSVLRIASKRGKLKALNTCASHICAVLILYVPMIGLSLVHRFAKHSSPVIHVTMANVYLLVPPVLNPIIYSIKTKQIRQGFLRILFSKRVGLAPT", "length": 328, "header": "tr|A0A5G2QW81-1|A0A5G2QW81_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QW81-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QW81-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81/entry#A0A5G2QW81-1", "sequence": { "sequence": "MAPWASLVTAPGSNASSGPPASFYLTGIPGSENVQPFLSLPFCVLYLTGTVGNCTILHIIHTDQRLHEPMYYFLAMLALTDLGMSISTLPTVLKTFWFDAKEIEINACVAQMYFIHTFSLMESAVLLAMALDRYVAICDPLRYCSKLTPRRIVYIGGFIVIRCSPVLPVILVRIPRLSFCHSHVLSHSFCLHQDIIRLACADISFNVLFGLFVVVFYWGVDALGIFLSYAFIFRSVLRIASKRGKLKALNTCASHICAVLILYVPMIGLSLVHRFAKHSSPVIHVTMANVYLLVPPVLNPIIYSIKTKQIRQGFLRILFSKRVGLAPT", "length": 328, "header": "tr|A0A5G2QW81-1|A0A5G2QW81_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QW81-1" }, "locus": { "chromosome": "9", "start_pos": 4947120, "end_pos": 4946137, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083988.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083988.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062439.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062439.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110255340", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255340", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QW81-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 328, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QW81-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QW81" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QW81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW81" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 303, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWA4-1", "uniprot_ac": "A0A5G2QWA4", "uniprot_id": "A0A5G2QWA4_PIG", "mass": { "chemical_mass": 67486.0, "monoisotopic_mass": 67486.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100628233", "type": "recommended", "evidence": [ { "id": "A0A5G2QWA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4" } ] } ], "protein_names": [ { "name": "Cationic amino acid transporter C-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QWA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWA4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100628233", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4", "locus": {} } ], "crossref": [ { "id": "A0A5G2QWA4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003248", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003248", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSSSCG00000032690", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000032690", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002293", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002293", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR43243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43243:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43243:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "32143", "url": "https://www.rhea-db.org/rhea/32143", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70935", "url": "https://www.rhea-db.org/rhea/70935", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71199", "url": "https://www.rhea-db.org/rhea/71199", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QWA4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RNK6", "url": "https://www.uniprot.org/uniprotkb/F1RNK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RNK6-1", "url": "https://www.uniprot.org/uniprotkb/F1RNK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPTSSTPSRMLHQYVCQFGQKLVRRRSLEPRDGSEGRMARCLNTLDLVSLGVGSTLGAGVYILAGAVAKDIAGPSIVLCFLVAALSSVLSGLCYAEFGARVPCSGSAYLYSYVTVGQLCAFITGWNLILSYIIGTASVARAWSSAFDSLIGNHISQVFKETFSPHVPHFLAKYPDFFALGLVLLLTGVLVLGARESALVTKVFTAINLLVLSFIILSGFIKGDLHNWQLTEQDYKLATAGSNDTSSLGPLGSGGFVPFGFGGIFHGAATCFFGFIGFDVIATTGEEARNPQRSIPLGIVISLFICFLAYFGVSATLTLMVPYYQIHPNSPLPQAFLQVGWDPARYVVAVGTLCALTSSLLGAMFPMPRVIYAMAEDGLLFRGLARIHARTRTPIMATLASGTLAGVMALLFELTDLVDLMSIGTLLAYSLVSFSVLVLRYQPDQNFSKKKTKEETEMDPVVEESPLESSLLDPISTTPTLKSGQIVYGCAFLLVLLLTILSLLLALWPSQVFSGDPGFTAGAVLLLLLIAGITVIIWRQPQNPSPLHFRVPALPVLPVLSIFVNVYLMMQMSSVTWAQFGVWMVIGFAIYFGYGIRHSLEENSDQEPPTSTSQALDKNPRSAKSA", "length": 626, "header": "tr|A0A5G2QWA4-1|A0A5G2QWA4_PIG Isoform 1 of Cationic amino acid transporter C-terminal domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100628233 PE=3 SV=2 CANONICAL=A0A5G2QWA4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4/entry#A0A5G2QWA4-1", "sequence": { "sequence": "MVPTSSTPSRMLHQYVCQFGQKLVRRRSLEPRDGSEGRMARCLNTLDLVSLGVGSTLGAGVYILAGAVAKDIAGPSIVLCFLVAALSSVLSGLCYAEFGARVPCSGSAYLYSYVTVGQLCAFITGWNLILSYIIGTASVARAWSSAFDSLIGNHISQVFKETFSPHVPHFLAKYPDFFALGLVLLLTGVLVLGARESALVTKVFTAINLLVLSFIILSGFIKGDLHNWQLTEQDYKLATAGSNDTSSLGPLGSGGFVPFGFGGIFHGAATCFFGFIGFDVIATTGEEARNPQRSIPLGIVISLFICFLAYFGVSATLTLMVPYYQIHPNSPLPQAFLQVGWDPARYVVAVGTLCALTSSLLGAMFPMPRVIYAMAEDGLLFRGLARIHARTRTPIMATLASGTLAGVMALLFELTDLVDLMSIGTLLAYSLVSFSVLVLRYQPDQNFSKKKTKEETEMDPVVEESPLESSLLDPISTTPTLKSGQIVYGCAFLLVLLLTILSLLLALWPSQVFSGDPGFTAGAVLLLLLIAGITVIIWRQPQNPSPLHFRVPALPVLPVLSIFVNVYLMMQMSSVTWAQFGVWMVIGFAIYFGYGIRHSLEENSDQEPPTSTSQALDKNPRSAKSA", "length": 626, "header": "tr|A0A5G2QWA4-1|A0A5G2QWA4_PIG Isoform 1 of Cationic amino acid transporter C-terminal domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100628233 PE=3 SV=2 CANONICAL=A0A5G2QWA4-1" }, "locus": { "chromosome": "6", "start_pos": 56591550, "end_pos": 56584584, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083162.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083162.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066218.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066218.2" } ] } }, { "isoform_ac": "F1RNK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4/entry#F1RNK6-1", "sequence": { "sequence": "MLHQYVCQFGQKLVRRRSLEPRDGSEGRMARCLNTLDLVSLGVGSTLGAGVYILAGAVAKDIAGPSIVLCFLVAALSSVLSGLCYAEFGARVPCSGSAYLYSYVTVGQLCAFITGWNLILSYIIGTASVARAWSSAFDSLIGNHISQVFKETFSPHVPHFLAKYPDFFALGLVLLLTGVLVLGARESALVTKVFTAINLLVLSFIILSGFIKGDLHNWQLTEQDYKLATAGSNDTSSLGPLGSGGFVPFGFGGIFHGAATCFFGFIGFDVIATTGEEARNPQRSIPLGIVISLFICFLAYFGVSATLTLMVPYYQIHPNSPLPQAFLQVGWDPARYVVAVGTLCALTSSLLGAMFPMPRVIYAMAEDGLLFRGLARIHARTRTPIMATLASGTLAGVMALLFELTDLVDLMSIGTLLAYSLVSFSVLVLRYQPDQNFSKKKTKEETEMDPVVEESPLESSLLDPISTTPTLKSGQIVYGCAFLLVLLLTILSLLLALWPSQVFSGDPGFTAGAVLLLLLIAGITVIIWRQPQNPSPLHFRVPALPVLPVLSIFVNVYLMMQMSSVTWAQFGVWMVIGFAIYFGYGIRHSLEENSDQEPPTSTSQALDKNPRSAKSA", "length": 616, "header": "tr|F1RNK6-1|A0A5G2QWA4_PIG Computationally mapped isoform of Cationic amino acid transporter C-terminal domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100628233 PE=3 SV=4 CANONICAL=A0A5G2QWA4-1" }, "locus": { "chromosome": "6", "start_pos": 56591550, "end_pos": 56585056, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003610.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003610.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003525.4", "url": "https://www.ensembl.org/id/ENSSSCP00000003525.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 115, "start_aa": "Thr", "end_pos": 115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr115", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 7, "start_aa": "Thr", "end_pos": 7, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr7", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RNK6", "url": "https://www.uniprot.org/uniprotkb/F1RNK6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWA4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWA4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "amino acid transmembrane transporter activity", "id": "GO:0015171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWA4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4" } ], "pmid": "" }, { "name": "L-arginine transmembrane transporter activity", "id": "GO:0061459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061459", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWA4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "32143", "name": "", "equation": "L-arginine(in) = L-arginine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "32143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32143" } ] }, { "id": "70935", "name": "", "equation": "L-lysine(in) = L-lysine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70935", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70935" } ] }, { "id": "71199", "name": "", "equation": "L-ornithine(in) = L-ornithine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71199", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71199" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWA4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 626, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWA4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWA4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA4" }, { "id": "PF13906", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13906" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cationic amino acid transporter C-terminal", "eco_id": "ECO_0000259", "start_pos": 549, "end_pos": 599, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 7, 115 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 }, { "start_pos": 446, "end_pos": 448 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWA8-1", "uniprot_ac": "A0A5G2QWA8", "uniprot_id": "A0A5G2QWA8_PIG", "mass": { "chemical_mass": 35309.0, "monoisotopic_mass": 35309.0 }, "refseq": { "ac": "XP_020937665", "name": "olfactory receptor 4S2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937665" }, "gene_names": [ { "name": "LOC110258737", "type": "recommended", "evidence": [ { "id": "A0A5G2QWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8" } ] }, { "name": "LOC110258737", "type": "synonym", "evidence": [ { "id": "XP_020937665", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937665" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4S2-like", "type": "synonym", "evidence": [ { "id": "XP_020937665", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937665" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110258737", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QWA8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWA8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110258737", "url": "https://www.ncbi.nlm.nih.gov/gene/110258737", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110258737", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258737", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QWA8", "url": "https://www.orthodb.org/?gene=A0A5G2QWA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020937665", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937665", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QWA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKINNVTEFVFWGLSQNLKVEKVCFMVFSFFSSVILLGNLLIMLTVYVGKLFKSPMYFFLNYLSFVDVCYSSVIAPKMIVDLLAKTKTISYDGCMLQLFAAHFLGCTEIFILTVMAYDRYVAICKPLHYMTIMDGERCNKMLLGTWLGGFLHSIIQVALVVQLPFCGPNEIDHYFCDIHPLLKLACADTYVIGVVVIANSGIITLVSFVILIISYIFILVYLRKQSAEGRHKALSTCGSHIAVVIIFFGPCTFMYMRPETTFSEDKMVALFYTIITPMLNPMIYTLRNAEVKNVMKKLGGRWIFWEAKGK", "length": 311, "header": "tr|A0A5G2QWA8-1|A0A5G2QWA8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258737 PE=3 SV=1 CANONICAL=A0A5G2QWA8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8/entry#A0A5G2QWA8-1", "sequence": { "sequence": "MGKINNVTEFVFWGLSQNLKVEKVCFMVFSFFSSVILLGNLLIMLTVYVGKLFKSPMYFFLNYLSFVDVCYSSVIAPKMIVDLLAKTKTISYDGCMLQLFAAHFLGCTEIFILTVMAYDRYVAICKPLHYMTIMDGERCNKMLLGTWLGGFLHSIIQVALVVQLPFCGPNEIDHYFCDIHPLLKLACADTYVIGVVVIANSGIITLVSFVILIISYIFILVYLRKQSAEGRHKALSTCGSHIAVVIIFFGPCTFMYMRPETTFSEDKMVALFYTIITPMLNPMIYTLRNAEVKNVMKKLGGRWIFWEAKGK", "length": 311, "header": "tr|A0A5G2QWA8-1|A0A5G2QWA8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258737 PE=3 SV=1 CANONICAL=A0A5G2QWA8-1" }, "locus": { "chromosome": "AEMK02000175.1", "start_pos": 346758, "end_pos": 345826, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082986.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082986.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068435.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068435.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110258737", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258737", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWA8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWA8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWA8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QY82-1", "uniprot_ac": "A0A5G2QY82", "uniprot_id": "A0A5G2QY82_PIG", "mass": { "chemical_mass": 83304.0, "monoisotopic_mass": 83304.0 }, "refseq": { "ac": "XP_020941775", "name": "E3 ubiquitin-protein ligase SMURF1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941775" }, "gene_names": [ { "name": "SMURF1", "type": "recommended", "evidence": [ { "id": "A0A5G2QY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ] }, { "name": "SMURF1", "type": "synonym", "evidence": [ { "id": "XP_020941775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941775" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase", "type": "recommended", "evidence": [ { "id": "A0A5G2QY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.26", "type": "synonym", "evidence": [ { "id": "A0A5G2QY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase SMURF1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_020941775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941775" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SMURF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82", "locus": { "chromosome": "3", "start_pos": 6037741, "end_pos": 6142575, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000030153", "url": "https://www.ensembl.org/id/ENSSSCG00000030153" } ] } } ], "crossref": [ { "id": "A0A5G2QY82", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QY82", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000030153", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000030153", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08382", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08382", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100621443", "url": "https://www.ncbi.nlm.nih.gov/gene/100621443", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QWDRPRH", "url": "https://omabrowser.org/oma/group/QWDRPRH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254:SF293", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254:SF293", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-201451", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201451", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2173791", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2173791", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4608870", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4608870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5632684", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5632684", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8941858", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8941858", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020941775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941775", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY82-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LTD6", "url": "https://www.uniprot.org/uniprotkb/I3LTD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LTD6-1", "url": "https://www.uniprot.org/uniprotkb/I3LTD6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAVSRLKDTGYQRLDLCKLNPSDTDAVRGQIVVSLQTRDRLGTGGPVVDCRGLLDNEGTVYEDSGPGRPLSCFMEEPAPYTDGPGAAAGGGNCRFVESPSQDQRVQAQRLRNPEVRGPLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRVPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQSLPLPSEGSVEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLDDWKSNTRLKHCGADSNVVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE", "length": 731, "header": "tr|A0A5G2QY82-1|A0A5G2QY82_PIG Isoform 1 of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=SMURF1 PE=4 SV=2 CANONICAL=A0A5G2QY82-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QY82-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82/entry#A0A5G2QY82-1", "sequence": { "sequence": "MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAVSRLKDTGYQRLDLCKLNPSDTDAVRGQIVVSLQTRDRLGTGGPVVDCRGLLDNEGTVYEDSGPGRPLSCFMEEPAPYTDGPGAAAGGGNCRFVESPSQDQRVQAQRLRNPEVRGPLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRVPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQSLPLPSEGSVEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLDDWKSNTRLKHCGADSNVVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE", "length": 731, "header": "tr|A0A5G2QY82-1|A0A5G2QY82_PIG Isoform 1 of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=SMURF1 PE=4 SV=2 CANONICAL=A0A5G2QY82-1" }, "locus": { "chromosome": "3", "start_pos": 6142250, "end_pos": 6040518, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088272.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088272.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069876.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069876.2" } ] } }, { "isoform_ac": "I3LTD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82/entry#I3LTD6-1", "sequence": { "sequence": "MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAVSRLKDTGYQRLDLCKLNPSDTDAVRGQIVVSLQTRDRLGTGGPVVDCRGLLDNEGTVYEDSGPGRPLSCFMEEPAPYTDGPGAAAGGGNCRFVESPSQDQRVQAQRLRNPEVRGPLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRVPSPLGTIPGGDEAFLYEFLLQGHTPEPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQSLPLPSEGSVEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLDDWKSNTRLKHCGADSNVVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE", "length": 757, "header": "tr|I3LTD6-1|A0A5G2QY82_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=SMURF1 PE=4 SV=3 CANONICAL=A0A5G2QY82-1" }, "locus": { "chromosome": "3", "start_pos": 6142250, "end_pos": 6040518, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028241.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028241.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027381.3", "url": "https://www.ensembl.org/id/ENSSSCP00000027381.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LTD6", "url": "https://www.uniprot.org/uniprotkb/I3LTD6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-201451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201451", "resource": "Reactome", "description": "Signaling by BMP" }, { "id": "R-SSC-2173791", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2173791", "resource": "Reactome", "description": "TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)" }, { "id": "R-SSC-4608870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4608870", "resource": "Reactome", "description": "Asymmetric localization of PCP proteins" }, { "id": "R-SSC-5632684", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5632684", "resource": "Reactome", "description": "Hedgehog 'on' state" }, { "id": "R-SSC-8941858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8941858", "resource": "Reactome", "description": "Regulation of RUNX3 expression and activity" }, { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K612-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Smurf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCKLNPSDTDAVRGQIVVSLQTRDRIGGGGSVVDCRGLLENEGTVYEDSGPGRPLSCLMEEPAPYTDGTGAAAGGGNCRFVESPSQDQRLLVQRLRNPEVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRIPSPLGTIPGGDEAFLYEFLLQGHTSEPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQPLQLPSEGSVEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE", "length": 757 }, "evidence": [ { "id": "A0A5G2QY82", "url": "https://omabrowser.org/oma/group/A0A5G2QY82/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MLS5-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "SMURF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCKLNPSDTDAVRGQIVVSLQTRDRIGTGGSVVDCRGLLESEGTVYEDSGPGRPLSCFMEEPAPYTDGPGAAAGGGTCRFVESPSQDQRLQAQRLRNPEVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRIPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMTHQCQLKEPSQPPPPPSEGSVEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLDDWKSNTRLKHCGADSNVVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE", "length": 731 }, "evidence": [ { "id": "A0A5G2QY82", "url": "https://omabrowser.org/oma/group/A0A5G2QY82/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CUN6-1", "protein_name": "E3 ubiquitin-protein ligase SMURF1", "gene_name": "Smurf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCKLNPSDTDAVRGQIVVSLQTRDRIGGGGSVVDCRGLLENEGTVYEDSGPGRPLSCLMEEPAPYTDGTGAAAGGGNCRFVESPSQDQRLLVQRLRNPEVRGPLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRIPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQPLQLPSEGSVEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE", "length": 731 }, "evidence": [ { "id": "A0A5G2QY82", "url": "https://omabrowser.org/oma/group/A0A5G2QY82/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HCE7-1", "protein_name": "E3 ubiquitin-protein ligase SMURF1", "gene_name": "SMURF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCKLNPSDTDAVRGQIVVSLQTRDRIGTGGSVVDCRGLLENEGTVYEDSGPGRPLSCFMEEPAPYTDSTGAAAGGGNCRFVESPSQDQRLQAQRLRNPDVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRIPSPSGTIPGGDAAFLYEFLLQGHTSEPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQPLPLPSEGSLEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE", "length": 757 }, "evidence": [ { "id": "A0A5G2QY82", "url": "https://omabrowser.org/oma/group/A0A5G2QY82/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V853-1", "protein_name": "E3 ubiquitin-protein ligase Smurf1", "gene_name": "Smurf", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNKLDYPRRNGTHKVRITILCARNLARKDLFRLPDPFAKVQVDGTGQVYSTEISKSSLDPKWNAHYDLFLGIGDAITITVWNQRKIHKGSGFLGCVRIPAFNIQSLKGAGFQRLDLGKLSPDDDELVRGQIIISLLSKDGPSSGNPLAIVGPSGDVRGPSEDDSSEDSLPEGWEERRTDNGRVYYVNHATKSTQWDRPRQPGVVGSSHATSPQQRHNTHNGNSGDRQAPAGPTRSTTCTNLMNNGHRSRDLSVTASDERRHSTEILSSVGKENTSPTTPVSATTTPGKKTSSSNSSSAGGRTLEQRPTNEPATPTSSTTSASVRLHSNDNHVKTPKHQTNGHAPPESTPTSPTGQQNYVNGNAQNGSTSGNGSGQAAQPQSASNGWTQEDAATTTSPSTTTSPPRHSQSPPTPNISPPASVTPSANGNVHSPNANSTPAGSGGGSRSYTAATPGQRSQRRSSRQQGEESSTRRRSSRGTRNGGTSGGGGGGGSGQRYASAAIAAANQAARPFLDLPPGYEMRTTQQGQVYFYHIPTGVSTWHDPRIPRDFDTQHLTLDAIGPLPSGWEQRKTASGRVYFVDHNNRTTQFTDPRLSGSILQMIRRGTVPPTSAANAGTPAPPSATPATPSAAAAVPPQATPASNATPTTLTTTTNPPHRIVPDLPQGLLEGADLLPKYRRDLVGKLRALRTELQTMQPQSGHCRLEVSRNEIFEESYRLIMKMRAKDMRKRLMVKFKGEEGLDYGGVAREWLHLLSREMLNPQYGLFQYSRDDHYTLQINPDSGVNPDHLSYFHFVGRTLGIAVFHGHCLDGGFTTPFYKQLLNKPITLGDIEGVDPDLHRSLTWMLESNISGIIESTFSVENNSFGALVVHELKPGGASIPVTEENKREYVKLYVNYRFMRGIEQQFLALQKGFCELIPSHLLRPFDERELELVIGGISSIDVNDWRNNTRLKHCTNETTQVLWFWQVVESYSSEMRARLLQFVTGSSRVPLQGFRALQGSTGAVGPRLFTIHLTADVPTQNLPKAHTCFNRIDLPPYETYQLLCDKLTQAVEETCGFAVE", "length": 1061 }, "evidence": [ { "id": "A0A5G2QY82", "url": "https://omabrowser.org/oma/group/A0A5G2QY82/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 18, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "ectoderm development", "id": "GO:0007398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007398", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "positive regulation of dendrite extension", "id": "GO:1903861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903861", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "negative regulation of activin receptor signaling pathway", "id": "GO:0032926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032926", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "engulfment of target by autophagosome", "id": "GO:0061736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061736", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "substrate localization to autophagosome", "id": "GO:0061753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061753", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "protein targeting to vacuole involved in autophagy", "id": "GO:0071211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071211", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "receptor catabolic process", "id": "GO:0032801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032801", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "positive regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000060", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor binding", "id": "GO:0005160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005160", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "SMAD binding", "id": "GO:0046332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "R-SMAD binding", "id": "GO:0070412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070412", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "I-SMAD binding", "id": "GO:0070411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070411", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" }, { "name": "activin receptor binding", "id": "GO:0070697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070697", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-201445", "name": "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-201445", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201445" } ] }, { "id": "R-SSC-201821", "name": "I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytoplasmic side of plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-201821", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201821" } ] }, { "id": "R-SSC-2160931", "name": "Disassembly of tight junctions", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cell junction", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2160931", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2160931" } ] }, { "id": "R-SSC-2160932", "name": "SMURF1 binds phosphorylated PARD6A", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cell junction, cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2160932", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2160932" } ] }, { "id": "R-SSC-2160935", "name": "SMURF1 ubiquitinates RHOA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cell junction, cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2160935", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2160935" } ] }, { "id": "R-SSC-4608852", "name": "SMURF1/2 ubiquitinates PRICKLE1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-SSC-4608816" ], "output_participant_list": [ "R-SSC-4608820" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-4608852", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4608852" } ] }, { "id": "R-SSC-4608854", "name": "SMURF1/2 are recruited to the DVL2:PARD6A complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-4608854", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4608854" } ] }, { "id": "R-SSC-5635865", "name": "SMURF1/2 dissociates from ub-PTCH1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "ciliary membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5635865", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5635865" } ] }, { "id": "R-SSC-8952419", "name": "SMURFs ubiquitinate RUNX3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-SSC-8952417" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8952419", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8952419" } ] }, { "id": "R-SSC-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983140" } ] }, { "id": "R-SSC-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983147" } ] }, { "id": "R-SSC-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983156" } ] }, { "id": "R-SSC-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983157" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-4608816", "participant_name": "PRICKLE1 [cytosol]", "crossref": [ { "id": "A0A287B8P6", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000034491", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000052476", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000044701", "database": "ENSEMBL", "url": "" }, { "id": "91793", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-4608820", "participant_name": "PRICKLE1 [cytosol]", "crossref": [ { "id": "ENSSSCT00000044701", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000034491", "database": "ENSEMBL", "url": "" }, { "id": "A0A287B8P6", "database": "UniProt", "url": "" }, { "id": "91793", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000052476", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-8952417", "participant_name": "PolyUb-RUNX3 [nucleoplasm]", "crossref": [ { "id": "XP_020951251.1", "database": "RefSeq", "url": "" }, { "id": "A0A5G2QVF3", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000065933", "database": "ENSEMBL", "url": "" }, { "id": "92518", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000090054", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000032686", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QY82-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 731, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QY82-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QY82" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 120, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" }, { "id": "PS50237", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50237" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HECT", "eco_id": "ECO_0000259", "start_pos": 394, "end_pos": 731, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY82" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 267, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 303, "end_pos": 305 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2I3-1", "uniprot_ac": "A0A5G2R2I3", "uniprot_id": "A0A5G2R2I3_PIG", "mass": { "chemical_mass": 98304.0, "monoisotopic_mass": 98304.0 }, "refseq": {}, "gene_names": [ { "name": "PGAP1", "type": "recommended", "evidence": [ { "id": "A0A5G2R2I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3" } ] } ], "protein_names": [ { "name": "GPI inositol-deacylase", "type": "recommended", "evidence": [ { "id": "A0A5G2R2I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3/entry#names_and_taxonomy" } ] }, { "name": "3.1.-.-", "type": "synonym", "evidence": [ { "id": "A0A5G2R2I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "GPI inositol-deacylase that catalyzes the remove of the acyl chain linked to the 2-OH position of inositol ring from the GPI-anchored protein (GPI-AP) in the endoplasmic reticulum. Initiates the post-attachment remodeling phase of GPI-AP biogenesis and participates in endoplasmic reticulum (ER)-to-Golgi transport of GPI-anchored protein.", "evidence": [ { "database": "UniProtKB", "id": "F1SN10", "url": "https://www.uniprot.org/uniprotkb/F1SN10#function" }, { "database": "UniProtKB", "id": "RU365011", "url": "https://www.uniprot.org/uniprotkb/RU365011#function" }, { "database": "UniProtKB", "id": "ARBA00093318", "url": "https://www.uniprot.org/uniprotkb/ARBA00093318#function" }, { "database": "UniProtKB", "id": "I3LKB2", "url": "https://www.uniprot.org/uniprotkb/I3LKB2#function" }, { "database": "UniProtKB", "id": "A0A5G2QNE0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNE0#function" }, { "database": "UniProtKB", "id": "A0A5G2QTF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTF0#function" }, { "database": "UniProtKB", "id": "A0A5G2QV34", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV34#function" }, { "database": "UniProtKB", "id": "A0A5G2R2I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3#function" }, { "database": "UniProtKB", "id": "A0A5G2RG16", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG16#function" }, { "database": "UniProtKB", "id": "A0A5G2RNM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNM6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PGAP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3", "locus": { "chromosome": "15", "start_pos": 100733560, "end_pos": 100820585, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016073", "url": "https://www.ensembl.org/id/ENSSSCG00000016073" } ] } } ], "crossref": [ { "id": "A0A5G2R2I3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2I3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016073", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016073", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100620753", "url": "https://www.ncbi.nlm.nih.gov/gene/100620753", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012908", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012908", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100620753", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620753", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YGLYYYY", "url": "https://omabrowser.org/oma/group/YGLYYYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "I3LKB2", "url": "https://www.orthodb.org/?gene=I3LKB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15495", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15495", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15495:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15495:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07819", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07819", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24660", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24660", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-162791", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-162791", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "83663", "url": "https://www.rhea-db.org/rhea/83663", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83787", "url": "https://www.rhea-db.org/rhea/83787", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QNE0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QV34", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QV34-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG16", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG16-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RNM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RNM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SN10", "url": "https://www.uniprot.org/uniprotkb/F1SN10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SN10-1", "url": "https://www.uniprot.org/uniprotkb/F1SN10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LKB2", "url": "https://www.uniprot.org/uniprotkb/I3LKB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LKB2-1", "url": "https://www.uniprot.org/uniprotkb/I3LKB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFMKIELPKKLAKRYPAYELYLYGEGSYAEEHKVLPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNGELVALYGGSLQKQTKFVHECIKTILKLYKGQEFAPKSVAIIGHSMGGLVARALLTLKNFKHDLINLLVTQATPHVAPVMPLDRFITDFYMTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPKLSDHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFFDLIDADTKQITQNPKKKLSVLNHHFIRHPAKHFEENPSIISDLTGTSMWVPVKVSKWTYVAYNESDKIYFTFPLANHRKIYTHVYCQSTMLVRKLVHFIRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHLVVYVPSIHGSKFVVDCEFFKKETRSIQLPVTHLFSFGLSSRKVILNTSGLFYNIELLNFGQIYQAFKISVVSKCSAVKEEITSIYKLHIPWSYEDSLTIAQVPSTTEIPVKLHIAQPENDSHVALLKMYTSSDCQYEVSCIQMIGFGRCVRFHGGALPAYVISSILLAYGGQLYSLFSTGHCLEYATMLDKEAKPYKVDPFVIMIKFLLGYKWFKELWDMCLLPELDAIVLTSQSMCFPLVSLILFLFGTCTAYWGGLLSSTSVRLLSSLWLALKRPSELPKEIKIISPDLPILTIVLIIVSWTTCGAFAILLTYFYYMFKIVHLQASLTTFKNSQTVNPKHSRRSEKKSNHHKDPAVHPLRLSANDAEDSLRMHSTVMNLLTWIVLLSMPSLIYWLKNLRYYFKLNPDPCKPLAFILIPTMALLGNTYTVSVKSSKLLKTTSQFPLPLAVGVIAFGSAHLYRVPCFVFIPLLLHALCNFM", "length": 866, "header": "tr|A0A5G2R2I3-1|A0A5G2R2I3_PIG Isoform 1 of GPI inositol-deacylase OS=Sus scrofa OX=9823 GN=PGAP1 PE=1 SV=2 CANONICAL=A0A5G2R2I3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QNE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3/entry#A0A5G2QNE0-1", "sequence": { "sequence": "MFLHSVNLWNLAFYALMVFMATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLAKRYPAYELYLYGEGSYAEEHKVLPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNGELVALYGGSLQKQTKFVHECIKTILKLYKGQEFAPKSVAIIGHSMGGLVARALLTLKNFKHDLINLLVTQATPHVAPVMPLDRFITDFYMTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPKLSDHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFFDLIDADTKQITQNPKKKLSVLNHHFIRHPAKHFEENPSIISDLTGTSMWVPVKVSKWTYVAYNESDKIYFTFPLANHRKIYTHVYCQSTMLVRKLVHFIRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHLVVYVPSIHGSKFVVDCEFFKKETRSIQLPVTHLFSFGLSSRKVILNTSGLFYNIELLNFGQIYQAFKISVVSKCSAVKEEITSIYKLHIPWSYEDSLTIAQVPSTTEIPVKLHIAQPENDSHVALLKMYTSSDCQYEVSCIQMIGFGRCVRFHGGALPAYVISSILLAYGGQLYSLFSTGHCLEYATMLDKEAKPYKVDPFVIMIKFLLGPSELPKEIKIISPDLPILTIVLIIVSWTTCGAFAILLTYFYYMFKIVHLQASLTTFKNSQTVNPKHSRRSEKKSNHHKDPAVHPLRLSANDAEDSLRMHSTVMNLLTWIVLLSMPSLIYWLKNLRYYFKLNPDPCKPLAFILIPTMALLGNTYTVSVKSSKLLKTTSQFPLPLAVGVIAFGSAHLYRVPCFVFIPLLLHALCNFM", "length": 846, "header": "tr|A0A5G2QNE0-1|A0A5G2QNE0_PIG Computationally mapped isoform of GPI inositol-deacylase OS=Sus scrofa OX=9823 GN=PGAP1 PE=1 SV=2 CANONICAL=A0A5G2R2I3-1" }, "locus": { "chromosome": "15", "start_pos": 100820475, "end_pos": 100741539, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075834.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075834.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066194.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066194.2" } ] } }, { "isoform_ac": "A0A5G2QTF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3/entry#A0A5G2QTF0-1", "sequence": { "sequence": "MFLHSVNLWNLAFYALMVFMATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLAKRYPAYELYLYGEGSYAEEHKVLPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNGELVALYGGSLQKQTKFVHECIKTILKLYKGQEFAPKSVAIIGHSMGGLVARALLTLKNFKHDLINLLVTQATPHVAPVMPLDRFITDFYMTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPKLSDHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFFDLIDADTKQITQNPKKKLSVLNHHFIRHPAKHFEENPSIISDLTGTSMWVPVKVSKWTYVAYNESDKIYFTFPLANHRKIYTHVYCQSTMLVRKLSLTLRLQDYPSLSHLVVYVPSIHGSKFVVDCEFFKKETRSIQLPVTHLFSFGLSSRKVILNTSGLFYNIELLNFGQIYQAFKISVVSKCSAVKEEITSIYKLHIPWSYEDSLTIAQVPSTTEIPVKLHIAQPENDSHVALLKMYTSSDCQYEVSCIQMIGFGRCVRFHGGALPAYVISSILLAYGGQLYSLFSTGHCLEYATMLDKEAKPYKVDPFVIMIKFLLGYKWFKELWDMCLLPELDAIVLTSQSMCFPLVSLILFLFGTCTAYWGGLLSSTSVRLLSSLWLALKRPSELPKEIKIISPDLPILTIVLIIVSWTTCGAFAILLTYFYYMFKIVHLQASLTTFKNSQTVNPKHSRRSEKKSNHHKDPAVHPLRLSANDAEDSLRMHSTVMNLLTWIVLLSMPSLIYWLKNLRYYFKLNPDPCKPLAFILIPTMALLGNTYTVSVKSSKLLKTTSQFPLPLAVGVIAFGSAHLYRVPCFVFIPLLLHALCNFM", "length": 891, "header": "tr|A0A5G2QTF0-1|A0A5G2R2I3_PIG Computationally mapped isoform of GPI inositol-deacylase OS=Sus scrofa OX=9823 GN=PGAP1 PE=1 SV=2 CANONICAL=A0A5G2R2I3-1" }, "locus": { "chromosome": "15", "start_pos": 100820475, "end_pos": 100741539, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069342.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069342.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067426.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067426.2" } ] } }, { "isoform_ac": "A0A5G2QV34-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3/entry#A0A5G2QV34-1", "sequence": { "sequence": "MFLHSVNLWNLAFYALMVFMATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLAKRYPAYELYLYGEGSYAEEHKVLPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNGELVALYGGSLQKQTKFVHECIKTILKLYKGQEFAPKSVAIIGHSMGGLVARALLTLKNFKHDLINLLVTQATPHVAPVMPLDRFITDFYMTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPKLSDHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFFDLIDADTKQITQNPKKKLSVLNHHFIRHPAKHFEENPSIISDLTGTSMWVPVKVSKWTYVAYNESDKIYFTFPLANHRKIYTHVYCQSTMLDTNSWIFGCINSTSMCRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHLVVYVPSIHGSKFVVDCEFFKKETRSIQLPVTHLFSFGLSSRKVILNTSGLFYNIELLNFGQIYQAFKISVVSKCSAVKEEITSIYKLHIPWSYEDSLTIAQVPSTTEIPVKLHIAQPENDSHVALLKMYTSSDCQYEVTVKTSFSQILGQVVRFHGGALPAYVISSILLAYGGQLYSLFSTGHCLEYATMLDKEAKPYKVDPFVIMIKFLLGPSELPKEIKIISPDLPILTIVLIIVSWTTCGAFAILLTYFYYMFKIVHLQASLTTFKNSQTVNPKHSRRSEKKSNHHKDPAVHPLRLSANDAEDSLRMHSTVMNLLTWIVLLSMPSLIYWLKNLRYYFKLNPDPCKPLAFILIPTMALLGNTYTVSVKSSKLLKTTSQFPLPLAVGVIAFGSAHLYRVPCFVFIPLLLHALCNFM", "length": 856, "header": "tr|A0A5G2QV34-1|A0A5G2R2I3_PIG Computationally mapped isoform of GPI inositol-deacylase OS=Sus scrofa OX=9823 GN=PGAP1 PE=1 SV=1 CANONICAL=A0A5G2R2I3-1" }, "locus": { "chromosome": "15", "start_pos": 100820475, "end_pos": 100741539, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079071.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079071.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062031.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062031.1" } ] } }, { "isoform_ac": "A0A5G2R2I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3/entry#A0A5G2R2I3-1", "sequence": { "sequence": "MFMKIELPKKLAKRYPAYELYLYGEGSYAEEHKVLPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNGELVALYGGSLQKQTKFVHECIKTILKLYKGQEFAPKSVAIIGHSMGGLVARALLTLKNFKHDLINLLVTQATPHVAPVMPLDRFITDFYMTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPKLSDHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFFDLIDADTKQITQNPKKKLSVLNHHFIRHPAKHFEENPSIISDLTGTSMWVPVKVSKWTYVAYNESDKIYFTFPLANHRKIYTHVYCQSTMLVRKLVHFIRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHLVVYVPSIHGSKFVVDCEFFKKETRSIQLPVTHLFSFGLSSRKVILNTSGLFYNIELLNFGQIYQAFKISVVSKCSAVKEEITSIYKLHIPWSYEDSLTIAQVPSTTEIPVKLHIAQPENDSHVALLKMYTSSDCQYEVSCIQMIGFGRCVRFHGGALPAYVISSILLAYGGQLYSLFSTGHCLEYATMLDKEAKPYKVDPFVIMIKFLLGYKWFKELWDMCLLPELDAIVLTSQSMCFPLVSLILFLFGTCTAYWGGLLSSTSVRLLSSLWLALKRPSELPKEIKIISPDLPILTIVLIIVSWTTCGAFAILLTYFYYMFKIVHLQASLTTFKNSQTVNPKHSRRSEKKSNHHKDPAVHPLRLSANDAEDSLRMHSTVMNLLTWIVLLSMPSLIYWLKNLRYYFKLNPDPCKPLAFILIPTMALLGNTYTVSVKSSKLLKTTSQFPLPLAVGVIAFGSAHLYRVPCFVFIPLLLHALCNFM", "length": 866, "header": "tr|A0A5G2R2I3-1|A0A5G2R2I3_PIG Isoform 1 of GPI inositol-deacylase OS=Sus scrofa OX=9823 GN=PGAP1 PE=1 SV=2 CANONICAL=A0A5G2R2I3-1" }, "locus": { "chromosome": "15", "start_pos": 100815380, "end_pos": 100741539, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091073.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091073.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064749.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064749.2" } ] } }, { "isoform_ac": "A0A5G2RG16-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3/entry#A0A5G2RG16-1", "sequence": { "sequence": "MFLHSVNLWNLAFYALMVFMATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLAKRYPAYELYLYGEGSYAEEHKVLPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNGELVALYGGSLQKQTKFVHECIKTILKLYKGQEFAPKSVAIIGHSMGGLVARALLTLKNFKHDLINLLVTQATPHVAPVMPLDRFITDFYMTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPKLSDHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFFDLIDADTKQITQNPKKKLSVLNHHFIRHPAKHFEENPSIISDLTGTSMWVPVKVSKWTYVAYNDTNSWIFGCINSTSMCRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHLVVYVPSIHGSKFVVDCEFFKKETRSIQLPVTHLFSFGLSSRKVILNTSGLFYNIELLNFGQIYQAFKISVVSKCSAVKEEITSIYKLHIPWSYEDSLTIAQVPSTTEIPVKLHIAQPENDSHVALLKMYTSSDCQYEVTVKTSFSQILGQVVRFHGGALPAYVISSILLAYGGQLYSLFSTGHCLEYATMLDKEAKPYKVDPFVIMIKFLLGYKWFKELWDMCLLPELDAIVLTSQSMCFPLVSLILFLFGTCTAYWGGLLSSTSVRLLSSLWLALKRPSELPKEIKIISPDLPILTIVLIIVSWTTCGAFAILLTYFYYMFKIVHLQASLTTFKNSQTVNPKHSRRSEKKSNHHKDPAVHPLRLSANDAEDSLRMHSTVMNLLTWIVLLSMPSLIYWLKNLRYYFKLNPDPCKPLAFILIPTMALLGNTYTVSVKSSKLLKTTSQFPLPLAVGVIAFGSAHLYRVPCFVFIPLLLHALCNFM", "length": 894, "header": "tr|A0A5G2RG16-1|A0A5G2RG16_PIG Computationally mapped isoform of GPI inositol-deacylase OS=Sus scrofa OX=9823 GN=PGAP1 PE=1 SV=1 CANONICAL=A0A5G2R2I3-1" }, "locus": { "chromosome": "15", "start_pos": 100820475, "end_pos": 100741539, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068796.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068796.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073862.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073862.1" } ] } }, { "isoform_ac": "A0A5G2RNM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3/entry#A0A5G2RNM6-1", "sequence": { "sequence": "MFLHSVNLWNLAFYALMVFMATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLAKRYPAYELYLYGEGSYAEEHKVLPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNGELVALYGGSLQKQTKFVHECIKTILKLYKGQEFAPKSVAIIGHSMGGLVARALLTLKNFKHDLINLLVTQATPHVAPVMPLDRFITDFYMTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPKLSDHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFFDLIDADTKQITQNPKKKLSVLNHHFIRHPAKHFEENPSIISDLTGTSMWVPVKVSKWTYVAYNESDKIYFTFPLANHRKIYTHVYCQSTMLDTNSWIFGCINSTSMCRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHLVVYVPSIHGSKFVVDCEFFKKETRSIQLPVTHLFSFGLSSRKVILNTSGLFYNIELLNFGQIYQAFKISVVSKCSAVKEEITSIYKLHIPWSYEDSLTIAQVPSTTEIPVKLHIAQPENDSHVALLKMYTSSDCQYEVTVKTSFSQILGQVIA", "length": 592, "header": "tr|A0A5G2RNM6-1|A0A5G2RNM6_PIG Computationally mapped isoform of GPI inositol-deacylase OS=Sus scrofa OX=9823 GN=PGAP1 PE=3 SV=1 CANONICAL=A0A5G2R2I3-1" }, "locus": { "chromosome": "15", "start_pos": 100820475, "end_pos": 100756232, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079888.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079888.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074511.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074511.1" } ] } }, { "isoform_ac": "F1SN10-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3/entry#F1SN10-1", "sequence": { "sequence": "MFLHSVNLWNLAFYALMVFMATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLAKRYPAYELYLYGEGSYAEEHKVLPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNGELVALYGGSLQKQTKFVHECIKTILKLYKGQEFAPKSVAIIGHSMGGLVARALLTLKNFKHDLINLLVTQATPHVAPVMPLDRFITDFYMTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPKLSDHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFFDLIDADTKQITQNPKKKLSVLNHHFIRHPAKHFEENPSIISDLTGTSMWVPVKVSKWTYVAYNVSILTMDLAFFSKNILSNRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHLVVYVPSIHGSKFVVDCEFFKKETRSIQLPVTHLFSFGLSSRKVILNTSGLFYNIELLNFGQIYQAFKISVVSKCSAVKEEITSIYKLHIPWSYEDSLTIAQVPSTTEIPVKLHIAQPENDSHVALLKMYTSSDCQYEVSCIQMIGFGRCVRFHGGALPAYVISSILLAYGGQLYSLFSTGHCLEYATMLDKEAKPYKVDPFVIMIKFLLGYKWFKELWDMCLLPELDAIVLTSQSMCFPLVSLILFLFGTCTAYWGGLLSSTSVRLLSSLWLALKRPSELPKEIKIISPDLPILTIVLIIVSWTTCGAFAILLTYFYYMFKIVHLQASLTTFKNSQTVNPKHSRRSEKKSNHHKDPAVHPLRLSANDAEDSLRMHSTVMNLLTWIVLLSMPSLIYWLKNLRYYFKLNPDPCKPLAFILIPTMALLGNTYTVSVKSSKLLKTTSQFPLPLAVGVIAFGSAHLYRVPCFVFIPLLLHALCNFM", "length": 894, "header": "tr|F1SN10-1|F1SN10_PIG Computationally mapped isoform of GPI inositol-deacylase OS=Sus scrofa OX=9823 GN=PGAP1 PE=1 SV=5 CANONICAL=A0A5G2R2I3-1" }, "locus": { "chromosome": "15", "start_pos": 100820475, "end_pos": 100741539, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017500.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017500.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017028.5", "url": "https://www.ensembl.org/id/ENSSSCP00000017028.5" } ] } }, { "isoform_ac": "I3LKB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3/entry#I3LKB2-1", "sequence": { "sequence": "MFLHSVNLWNLAFYALMVFMATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLAKRYPAYELYLYGEGSYAEEHKVLPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNGELVALYGGSLQKQTKFVHECIKTILKLYKGQEFAPKSVAIIGHSMGGLVARALLTLKNFKHDLINLLVTQATPHVAPVMPLDRFITDFYMTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPKLSDHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFFDLIDADTKQITQNPKKKLSVLNHHFIRHPAKHFEENPSIISDLTGTSMWVPVKVSKWTYVAYNESDKIYFTFPLANHRKIYTHVYCQSTMLDTNSWIFGCINSTSMCRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHLVVYVPSIHGSKFVVDCEFFKKETRSIQLPVTHLFSFGLSSRKVILNTSGLFYNIELLNFGQIYQAFKISVVSKCSAVKEEITSIYKLHIPWSYEDSLTIAQVPSTTEIPVKLHIAQPENDSHVALLKMYTSSDCQYEVTVKTSFSQILGQVVRFHGGALPAYVISSILLAYGGQLYSLFSTGHCLEYATMLDKEAKPYKVDPFVIMIKFLLGYKWFKELWDMCLLPELDAIVLTSQSMCFPLVSLILFLFGTCTAYWGGLLSSTSVRLLSSLWLALKRPSELPKEIKIISPDLPILTIVLIIVSWTTCGAFAILLTYFYYMFKIVHLQASLTTFKNSQTVNPKHSRRSEKKSNHHKDPAVHPLRLSANDAEDSLRMHSTVMNLLTWIVLLSMPSLIYWLKNLRYYFKLNPDPCKPLAFILIPTMALLGNTYTVSVKSSKLLKTTSQFPLPLAVGVIAFGSAHLYRVPCFVFIPLLLHALCNFICSSGPCCFGII", "length": 933, "header": "tr|I3LKB2-1|A0A5G2R2I3_PIG Computationally mapped isoform of GPI inositol-deacylase OS=Sus scrofa OX=9823 GN=PGAP1 PE=1 SV=2 CANONICAL=A0A5G2R2I3-1" }, "locus": { "chromosome": "15", "start_pos": 100820475, "end_pos": 100740030, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023196.4", "url": "https://www.ensembl.org/id/ENSSSCT00000023196.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024526.2", "url": "https://www.ensembl.org/id/ENSSSCP00000024526.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LKB2", "url": "https://www.uniprot.org/uniprotkb/I3LKB2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100620753", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620753", "resource": "KEGG Pathway" }, { "id": "R-SSC-162791", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-162791", "resource": "Reactome", "description": "Attachment of GPI anchor to uPAR" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SE06-1", "protein_name": "GPI inositol-deacylase", "gene_name": "PGAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLHSVNLWNLAFYALMVFMATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLAKRYPAYELYLYGEGSYAEEHKVLPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNEELVALYGGSLQKQTKFVHECIKTILKLYKGQEFAPKSVAIVGHSMGGLVARALLTLKNFKQDLINLLVTQATPHVAPVMPLDRFITDFYMTVNNYWILNARQINLTTLSVAGGFRDYQVRSGLTFLPKLSHHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFFDLIDADTKQITQNPKKKLSVLNHHFIRHPAKHFEENPSIISDLTGTSMWVPVKVSKWTYVAYNESDKIYFTFPLANHRKIYTHVYCQSTMLDTNSWIFGCINSTSMCRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHLVVYVPSIHGSKFVVDCEFFKKETRSIQLPVTHLFSFGLSSRKVILNTSGLFYNIELLNFGQIYQAFKINVVSKCSGVKEEITSIYKLHIPWSYEDSLTIAQVPSSTEISVKLHIAQPDNDSHVALLKMYTSSDCQYEVTVKTSFSQILGQVVRFHGGALPAYVISSILLAYGGQLYSLFSTGHCLEYATMLDKEAKPYKVDPFVIMVKFLLGPSELPKDIKIISPDLPILTIIFILISWTTCGAFAILLTYLYYVFKIVHLQASLTMFKNSQTVNPKHSRRSEKKSNHHKDSAVHHLRLSSSDAEDSLRMHSTLINLLTWIVLLSMPSLIYWLKNLRYYFKLNPDPCKPLAFILIPTMAILGNTYTTSIKSSKLLKTTSQFPLPLAVGVIAFGSSHLYRVPCFVFIPLLLHALCNFM", "length": 856 }, "evidence": [ { "id": "A0A5G2R2I3", "url": "https://omabrowser.org/oma/group/A0A5G2R2I3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UUQ7-1", "protein_name": "GPI inositol-deacylase", "gene_name": "Pgap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFLHSVNLWNLAFYVFMVFLATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLTKRYPAYELYLYGEGSYAEEHKILPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNEELVALYGGSLQKQTKFVHECIKAILKLYKGQEFAPTSVAIIGHSMGGLVARALLTLKNFKQDLINLLVTQATPHVAPVMPLDRFITEFYMNVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPKLSHYTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTIRAFFDLIDADTKQITQKPKKKLSVLNHHFIRHPAKQFEENPSIISDLTGTSMWVPVKVSRWSYVAYNESDKIYFAFPLANHRKIYTHAYCQSTMLDTNSWIFGCINSTSMCRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHIVVYVPSVHGSKFVVDCEFFKKEARSMQLPVTHLFSFGLSSRKVTLNTNGLYYNIELLNFGQIYQAFKVNVVSKCTGSKEEITSIYKLHIPWSYEDSLTIAQVPSSTDISLKLHVAQPENDSHVALLKMYTSSDCQYEVTIKTSFPQILGQVVRFHGGALPAYVVSSILLAYGGQLYSLLSTGYCLEYSTILDKEAKPYKVDPFVIMIKFLLGYKWFKELWDAVLLPELDAIVLTSQSMCFPLVSLILFLFGTCTAYWSGLLSSTSVQLLSSLWLALKRPAELPKDIKVMSPDLPVLTVVFLIVSWTTCGALAILLSYLYYVFKVVHLQASLTTFKNNQPVNPKHSRRSEKKSNHHKDSAVQSLRLCANDAEDSLRMHSTVINLLTWVVLLSMPSLIYWLKNLRYYFKLSPDPCKPLAFLLIPAIAILGNTHTVSVKSSKLLKTVSQFPLPLAVGVIAFGSSHLYRVPCFVIIPLVFHALCNFM", "length": 922 }, "evidence": [ { "id": "A0A5G2R2I3", "url": "https://omabrowser.org/oma/group/A0A5G2R2I3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q75T13-1", "protein_name": "GPI inositol-deacylase", "gene_name": "PGAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLHSVNLWNLAFYVFMVFLATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLAKRYPAYELYLYGEGSYAEEHKILPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNEELVALYGGSLQKQTKFVHECIKTILKLYKGQEFAPKSVAIIGHSMGGLVARALLTLKNFKHDLINLLITQATPHVAPVMPLDRFITDFYTTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPKLSHHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFFDLIDADTKQITQNSKKKLSVLYHHFIRHPSKHFEENPAIISDLTGTSMWVLVKVSKWTYVAYNESEKIYFTFPLENHRKIYTHVYCQSTMLDTNSWIFACINSTSMCLQGVDLSWKAELLPTIKYLTLRLQDYPSLSHLVVYVPSVRGSKFVVDCEFFKKEKRYIQLPVTHLFSFGLSSRKVVLNTNGLYYNLELLNFGQIYQAFKINVVSKCSAVKEEITSIYRLHIPWSYEDSLTIAQAPSSTEISLKLHIAQPENNTHVALFKMYTSSDCRYEVTVKTSFSQILGQVVRFHGGALPAYVVSNILLAYRGQLYSLFSTGCCLEYATMLDKEAKPYKVDPFVIIIKFLLGYKWFKELWDVLLLPELDAVILTCQSMCFPLISLILFLFGTCTAYWSGLLSSASVRLLSSLWLALKRPSELPKDIKMISPDLPFLTIVLIIVSWTTCGALAILLSYLYYVFKVVHLQASLTTFKNSQPVNPKHSRRSEKKSNHHKDSSIHHLRLSANDAEDSLRMHSTVINLLTWIVLLSMPSLIYWLKNLRYYFKLNPDPCKPLAFILIPTMAILGNTYTVSIKSSKLLKTTSQFPLPLAVGVIAFGSAHLYRLPCFVFIPLLLHALCNFM", "length": 922 }, "evidence": [ { "id": "A0A5G2R2I3", "url": "https://omabrowser.org/oma/group/A0A5G2R2I3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q765A7-1", "protein_name": "GPI inositol-deacylase", "gene_name": "Pgap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFLHSVNLWNLAFYVFMVFLATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLTKRYPAYELYLYGEGSYAEEHKILPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNEELVALYGGSLQKQTKFVHECIKAILKLYKGQEFPPTSVAIIGHSMGGLVARALLTLKNFKQDLINLLVTQATPHVAPVMPLDRFITEFYMTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPTLSHHTSALSVVTSAVPKTWVSTDHLSIVWCKQLQLTTIRAFFDLIDADTKQITQKSKKKLSVLNHHFIRHPAKQFEENPSIISDLTGTSMWVPVKVSRWSYVAYNESDKIYFAFPLANHRKVYTHAYCQSTMLDTNSWIFGCINSTSMCRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHIVVYVPSVHGSKFVVDCEFFKKEARSIQLPVTHLFSFGLSSRKAIINTSGRYYNIELLNLGQIYQAFKVNVVSKCTGGKEEITSIYKLHIPWSYEDSLTIAQVPSSVDISLKLHVAQPENDSHVALLKMYTSSDCQYEVTIKTSFPQILGQVVRFHGGALPAYVVSSILLAYGGQLYSLLSTGFCLEYGTMLDKEAKPYKVDPFVIMIKFLLGYKWFKELWDAVLLPELDAIVLTSQSMCFPLVSLILFLFGTCTAYWSGLLSSASVQLLSSLWLALKRPAELPKDVKVMSPDLPVLTVVFLIISWTTCGALAILLSYLYYVFKVVHLQASLTTFKNNQPVNPKHSRRSEKKSNHHKDSAIQNPRLSANDAEDSLRMHSTVINLLTWVVLLSMPSLIYWSKNLRYYFKLNPDPCKPLAFLLIPAIAVLGNTHTVSIKSSKLLKTASQFPLPLAVGVIAFGSSHLYRVPCFVIIPLVFHSLCNFM", "length": 922 }, "evidence": [ { "id": "A0A5G2R2I3", "url": "https://omabrowser.org/oma/group/A0A5G2R2I3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9W495-1", "protein_name": "GPI inositol-deacylase", "gene_name": "PGAP1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFMFRNCAVLLVIGSICCFIYGLFRLHVEVEPNACRMTYMFGEPMFAKVGVRDGDQYPNYALYYYYEGLRQPLDPLKRRMTGAPVIFVPGNAGSYKQVRSLASVALRKAMSNDAGIHLDYYTIDYDEELSALYGGYLHRQQSYLKLCIRTILSIYEGRTEQPSIVLIGHSMGGKLAQSVLVDPAIGQHINTIISISTPLDQPVLNLDTQLEEFYDQTDAVLSKLRTATVPTMTTNVCDSLHQRPPSVQRMASQDSSARLDNVLLISTGGGNRDLLVRPGLTSSRFNDLHAMTSAIPKVSLSCDHLSAVWCLQFMQAINRFLFSVAYVREDRSSIAFGTNKQRNLQTALSTFVKPRRRQQNTVRFGAAGNWHEERRLVINKYFTNGLKGTFFDLIGLQRQERYRKAAIEALNVDDEDWLFGCSAEDNNKTGQLYCEKATSLMHLVQWLPNEDREPRSIALLDLHNLRKTYVHWTHLLVRLPPSAKRIGYNLDIYDPKERVTDIKMPRWYTMAKLPLINETLQGTLHHRVRISEMVDPYQSIRVIVEPLQCINPEYRVTARICVPWAAGFERFQTLKSFDQKPQLYVNVPTLVPRHYNTTLNPVTLELYLDPTCRYRISYEYSYSSALSRLVLEFYGWLPAHLVCVLLIVLRKQVETFYDVGTFRSLRPYVGYLQYTSLYIVTACRLLKKLIISSRVFPEPEPLDYSINVSIVIHCAAIALSLLATLGTWLALTLYGNAFYRLALRITRLSQATSNVMISIMTHLPITYGILTIATAMGTCSGVGLLLAFVFYFLMLSNAYKDYLEDFLWQKAANLVRGKPSAVTEQEDATEEQNEEQNALKQNDEQKQQQQEEEEPEACVGLQNFSFHVTLLLMLFVQLLLNAPSSLAWLRSRRHGINLPDPSLYPSIVVLASLSLLLQLRAPQKCQGYWMLSIAFYILAGVVLLYCQAAIYRLTYVIAGAFALLSAHQSLWILWGRVSRV", "length": 980 }, "evidence": [ { "id": "A0A5G2R2I3", "url": "https://omabrowser.org/oma/group/A0A5G2R2I3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3" } ], "pmid": "" }, { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hydrolase activity, acting on ester bonds", "id": "GO:0016788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016788", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3" } ], "pmid": "" }, { "name": "deacylase activity", "id": "GO:0160215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160215", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "83663", "name": "", "equation": "[protein]-C-terminal carboxyl phosphoethanolamide-GPI(H8) + H2O = [protein]-C-terminal carboxyl phosphoethanolamide-GPI(deacylinositol-H8) + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83663", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83663" } ] }, { "id": "83787", "name": "", "equation": "[protein]-C-terminal carboxyl phosphoethanolamide-GPI(H7) + H2O = [protein]-C-terminal carboxyl phosphoethanolamide-GPI(deacylinositol-H7) + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83787", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83787" } ] }, { "id": "R-SSC-162729", "name": "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-113519", "R-SSC-162687" ], "output_participant_list": [ "R-ALL-1524021", "R-SSC-162703" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-162729", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-162729" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-113519", "participant_name": "H2O [endoplasmic reticulum lumen]", "crossref": [ { "id": "15377", "database": "ChEBI", "url": "" }, { "id": "8145132", "database": "PubChem Substance", "url": "" }, { "id": "C00001", "database": "COMPOUND", "url": "" }, { "id": "HMDB0002111", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-1524021", "participant_name": "LCFA(-) [endoplasmic reticulum membrane]", "crossref": [ { "id": "57560", "database": "ChEBI", "url": "" }, { "id": "C00060", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-SSC-162687", "participant_name": "PLAUR [endoplasmic reticulum membrane]", "crossref": [ { "id": "A0A8D1E2A2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000032434", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000052797", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000052717", "database": "ENSEMBL", "url": "" }, { "id": "XP_003127246.2", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-162703", "participant_name": "PLAUR [endoplasmic reticulum membrane]", "crossref": [ { "id": "ENSSSCP00000052797", "database": "ENSEMBL", "url": "" }, { "id": "XP_003127246.2", "database": "RefSeq", "url": "" }, { "id": "A0A8D1E2A2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000032434", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000052717", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2I3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 866, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2I3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2I3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3" }, { "id": "PF07819", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07819" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GPI inositol-deacylase PGAP1-like alpha/beta", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 255, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R2I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I3" }, { "id": "PF25140", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25140" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GPI inositol-deacylase transmembrane", "eco_id": "ECO_0000259", "start_pos": 541, "end_pos": 865, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 431, "end_pos": 433 }, { "start_pos": 504, "end_pos": 506 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3N7-1", "uniprot_ac": "A0A5G2R3N7", "uniprot_id": "A0A5G2R3N7_PIG", "mass": { "chemical_mass": 52887.0, "monoisotopic_mass": 52887.0 }, "refseq": {}, "gene_names": [ { "name": "NDUFS2", "type": "recommended", "evidence": [ { "id": "A0A5G2R3N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A5G2R3N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7/entry#names_and_taxonomy" } ] }, { "name": "7.1.1.2", "type": "synonym", "evidence": [ { "id": "A0A5G2R3N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7/entry#names_and_taxonomy" } ] }, { "name": "Complex I-49kD", "type": "synonym", "evidence": [ { "id": "A0A5G2R3N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7/entry#names_and_taxonomy" } ] }, { "name": "NADH-ubiquinone oxidoreductase 49 kDa subunit", "type": "synonym", "evidence": [ { "id": "A0A5G2R3N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NDUFS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7", "locus": { "chromosome": "4", "start_pos": 89246960, "end_pos": 89257085, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006358", "url": "https://www.ensembl.org/id/ENSSSCG00000006358" } ] } } ], "crossref": [ { "id": "A0A5G2R3N7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3N7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006358", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006358", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "5GPN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5GPN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "5GUP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5GUP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2C", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2C&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2D&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2E", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2E&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2F", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2F&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2H", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2H&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2K", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2K&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V30", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V30&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V31", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V31&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V32", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V32&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V33", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V33&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V3M", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V3M&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VB7", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VB7&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VBL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VBL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VBN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VBN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VBZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VBZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VC0", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VC0&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VWJ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VWJ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VXP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VXP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VXS", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VXS&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VXU", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VXU&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VY1", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VY1&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VY8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VY8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VY9", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VY9&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYA", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYA&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYE", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYE&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYF", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYF&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYG", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYG&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYS", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYS&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZ1", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZ1&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZ8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZ8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZV", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZV&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W00", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W00&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W0H", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W0H&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W0R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W0R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1O", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1O&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1P", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1P&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1T", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1T&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1U", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1U&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1V", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1V&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W20", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W20&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2K", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2K&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2L", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2L&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2U", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2U&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2Y", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2Y&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W31", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W31&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W32", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W32&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W35", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W35&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4C", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4C&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4D&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4E", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4E&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4F", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4F&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4G", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4G&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4J", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4J&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4K", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4K&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4L", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4L&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4M", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4M&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4N", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4N&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4Q", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4Q&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZO8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZO8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSK", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSK&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSM", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSM&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSO", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSO&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZXZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZXZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CE2", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CE2&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9J6H", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9J6H&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9J6W", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9J6W&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "F1S1A8", "url": "https://www.ebi.ac.uk/intact/interactors/id:F1S1A8*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11993", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11993", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11993:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11993:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00005gpn", "url": "https://www.rcsb.org/structure/pdb_00005gpn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00005gup", "url": "https://www.rcsb.org/structure/pdb_00005gup", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2c", "url": "https://www.rcsb.org/structure/pdb_00007v2c", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2d", "url": "https://www.rcsb.org/structure/pdb_00007v2d", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2e", "url": "https://www.rcsb.org/structure/pdb_00007v2e", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2f", "url": "https://www.rcsb.org/structure/pdb_00007v2f", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2h", "url": "https://www.rcsb.org/structure/pdb_00007v2h", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2k", "url": "https://www.rcsb.org/structure/pdb_00007v2k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2r", "url": "https://www.rcsb.org/structure/pdb_00007v2r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v30", "url": "https://www.rcsb.org/structure/pdb_00007v30", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v31", "url": "https://www.rcsb.org/structure/pdb_00007v31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v32", "url": "https://www.rcsb.org/structure/pdb_00007v32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v33", "url": "https://www.rcsb.org/structure/pdb_00007v33", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v3m", "url": "https://www.rcsb.org/structure/pdb_00007v3m", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vb7", "url": "https://www.rcsb.org/structure/pdb_00007vb7", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vbl", "url": "https://www.rcsb.org/structure/pdb_00007vbl", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vbn", "url": "https://www.rcsb.org/structure/pdb_00007vbn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vbz", "url": "https://www.rcsb.org/structure/pdb_00007vbz", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vc0", "url": "https://www.rcsb.org/structure/pdb_00007vc0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vwj", "url": "https://www.rcsb.org/structure/pdb_00007vwj", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vxp", "url": "https://www.rcsb.org/structure/pdb_00007vxp", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vxs", "url": "https://www.rcsb.org/structure/pdb_00007vxs", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vxu", "url": "https://www.rcsb.org/structure/pdb_00007vxu", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vy1", "url": "https://www.rcsb.org/structure/pdb_00007vy1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vy8", "url": "https://www.rcsb.org/structure/pdb_00007vy8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vy9", "url": "https://www.rcsb.org/structure/pdb_00007vy9", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vya", "url": "https://www.rcsb.org/structure/pdb_00007vya", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vye", "url": "https://www.rcsb.org/structure/pdb_00007vye", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vyf", "url": "https://www.rcsb.org/structure/pdb_00007vyf", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vyg", "url": "https://www.rcsb.org/structure/pdb_00007vyg", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vyh", "url": "https://www.rcsb.org/structure/pdb_00007vyh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vyn", "url": "https://www.rcsb.org/structure/pdb_00007vyn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vys", "url": "https://www.rcsb.org/structure/pdb_00007vys", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vz1", "url": "https://www.rcsb.org/structure/pdb_00007vz1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vz8", "url": "https://www.rcsb.org/structure/pdb_00007vz8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vzv", "url": "https://www.rcsb.org/structure/pdb_00007vzv", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vzw", "url": "https://www.rcsb.org/structure/pdb_00007vzw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w00", "url": "https://www.rcsb.org/structure/pdb_00007w00", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w0h", "url": "https://www.rcsb.org/structure/pdb_00007w0h", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w0r", "url": "https://www.rcsb.org/structure/pdb_00007w0r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1o", "url": "https://www.rcsb.org/structure/pdb_00007w1o", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1p", "url": "https://www.rcsb.org/structure/pdb_00007w1p", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1t", "url": "https://www.rcsb.org/structure/pdb_00007w1t", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1u", "url": "https://www.rcsb.org/structure/pdb_00007w1u", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1v", "url": "https://www.rcsb.org/structure/pdb_00007w1v", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1z", "url": "https://www.rcsb.org/structure/pdb_00007w1z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w20", "url": "https://www.rcsb.org/structure/pdb_00007w20", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2k", "url": "https://www.rcsb.org/structure/pdb_00007w2k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2l", "url": "https://www.rcsb.org/structure/pdb_00007w2l", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2r", "url": "https://www.rcsb.org/structure/pdb_00007w2r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2u", "url": "https://www.rcsb.org/structure/pdb_00007w2u", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2y", "url": "https://www.rcsb.org/structure/pdb_00007w2y", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w31", "url": "https://www.rcsb.org/structure/pdb_00007w31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w32", "url": "https://www.rcsb.org/structure/pdb_00007w32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w35", "url": "https://www.rcsb.org/structure/pdb_00007w35", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4c", "url": "https://www.rcsb.org/structure/pdb_00007w4c", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4d", "url": "https://www.rcsb.org/structure/pdb_00007w4d", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4e", "url": "https://www.rcsb.org/structure/pdb_00007w4e", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4f", "url": "https://www.rcsb.org/structure/pdb_00007w4f", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4g", "url": "https://www.rcsb.org/structure/pdb_00007w4g", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4j", "url": "https://www.rcsb.org/structure/pdb_00007w4j", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4k", "url": "https://www.rcsb.org/structure/pdb_00007w4k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4l", "url": "https://www.rcsb.org/structure/pdb_00007w4l", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4m", "url": "https://www.rcsb.org/structure/pdb_00007w4m", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4n", "url": "https://www.rcsb.org/structure/pdb_00007w4n", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4q", "url": "https://www.rcsb.org/structure/pdb_00007w4q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zo8", "url": "https://www.rcsb.org/structure/pdb_00008zo8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsk", "url": "https://www.rcsb.org/structure/pdb_00008zsk", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsl", "url": "https://www.rcsb.org/structure/pdb_00008zsl", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsm", "url": "https://www.rcsb.org/structure/pdb_00008zsm", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsn", "url": "https://www.rcsb.org/structure/pdb_00008zsn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zso", "url": "https://www.rcsb.org/structure/pdb_00008zso", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsq", "url": "https://www.rcsb.org/structure/pdb_00008zsq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsr", "url": "https://www.rcsb.org/structure/pdb_00008zsr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zxz", "url": "https://www.rcsb.org/structure/pdb_00008zxz", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009ce2", "url": "https://www.rcsb.org/structure/pdb_00009ce2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009j6h", "url": "https://www.rcsb.org/structure/pdb_00009j6h", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009j6w", "url": "https://www.rcsb.org/structure/pdb_00009j6w", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5GPN", "url": "https://www.rcsb.org/structure/5GPN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5GUP", "url": "https://www.rcsb.org/structure/5GUP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2C", "url": "https://www.rcsb.org/structure/7V2C", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2D", "url": "https://www.rcsb.org/structure/7V2D", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2E", "url": "https://www.rcsb.org/structure/7V2E", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2F", "url": "https://www.rcsb.org/structure/7V2F", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2H", "url": "https://www.rcsb.org/structure/7V2H", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2K", "url": "https://www.rcsb.org/structure/7V2K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2R", "url": "https://www.rcsb.org/structure/7V2R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V30", "url": "https://www.rcsb.org/structure/7V30", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V31", "url": "https://www.rcsb.org/structure/7V31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V32", "url": "https://www.rcsb.org/structure/7V32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V33", "url": "https://www.rcsb.org/structure/7V33", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V3M", "url": "https://www.rcsb.org/structure/7V3M", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VB7", "url": "https://www.rcsb.org/structure/7VB7", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VBL", "url": "https://www.rcsb.org/structure/7VBL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VBN", "url": "https://www.rcsb.org/structure/7VBN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VBZ", "url": "https://www.rcsb.org/structure/7VBZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VC0", "url": "https://www.rcsb.org/structure/7VC0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VWJ", "url": "https://www.rcsb.org/structure/7VWJ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VXP", "url": "https://www.rcsb.org/structure/7VXP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VXS", "url": "https://www.rcsb.org/structure/7VXS", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VXU", "url": "https://www.rcsb.org/structure/7VXU", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VY1", "url": "https://www.rcsb.org/structure/7VY1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VY8", "url": "https://www.rcsb.org/structure/7VY8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VY9", "url": "https://www.rcsb.org/structure/7VY9", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYA", "url": "https://www.rcsb.org/structure/7VYA", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYE", "url": "https://www.rcsb.org/structure/7VYE", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYF", "url": "https://www.rcsb.org/structure/7VYF", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYG", "url": "https://www.rcsb.org/structure/7VYG", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYH", "url": "https://www.rcsb.org/structure/7VYH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYN", "url": "https://www.rcsb.org/structure/7VYN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYS", "url": "https://www.rcsb.org/structure/7VYS", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZ1", "url": "https://www.rcsb.org/structure/7VZ1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZ8", "url": "https://www.rcsb.org/structure/7VZ8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZV", "url": "https://www.rcsb.org/structure/7VZV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZW", "url": "https://www.rcsb.org/structure/7VZW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W00", "url": "https://www.rcsb.org/structure/7W00", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W0H", "url": "https://www.rcsb.org/structure/7W0H", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W0R", "url": "https://www.rcsb.org/structure/7W0R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1O", "url": "https://www.rcsb.org/structure/7W1O", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1P", "url": "https://www.rcsb.org/structure/7W1P", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1T", "url": "https://www.rcsb.org/structure/7W1T", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1U", "url": "https://www.rcsb.org/structure/7W1U", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1V", "url": "https://www.rcsb.org/structure/7W1V", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1Z", "url": "https://www.rcsb.org/structure/7W1Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W20", "url": "https://www.rcsb.org/structure/7W20", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2K", "url": "https://www.rcsb.org/structure/7W2K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2L", "url": "https://www.rcsb.org/structure/7W2L", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2R", "url": "https://www.rcsb.org/structure/7W2R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2U", "url": "https://www.rcsb.org/structure/7W2U", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2Y", "url": "https://www.rcsb.org/structure/7W2Y", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W31", "url": "https://www.rcsb.org/structure/7W31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W32", "url": "https://www.rcsb.org/structure/7W32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W35", "url": "https://www.rcsb.org/structure/7W35", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4C", "url": "https://www.rcsb.org/structure/7W4C", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4D", "url": "https://www.rcsb.org/structure/7W4D", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4E", "url": "https://www.rcsb.org/structure/7W4E", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4F", "url": "https://www.rcsb.org/structure/7W4F", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4G", "url": "https://www.rcsb.org/structure/7W4G", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4J", "url": "https://www.rcsb.org/structure/7W4J", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4K", "url": "https://www.rcsb.org/structure/7W4K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4L", "url": "https://www.rcsb.org/structure/7W4L", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4M", "url": "https://www.rcsb.org/structure/7W4M", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4N", "url": "https://www.rcsb.org/structure/7W4N", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4Q", "url": "https://www.rcsb.org/structure/7W4Q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZO8", "url": "https://www.rcsb.org/structure/8ZO8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSK", "url": "https://www.rcsb.org/structure/8ZSK", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSL", "url": "https://www.rcsb.org/structure/8ZSL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSM", "url": "https://www.rcsb.org/structure/8ZSM", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSN", "url": "https://www.rcsb.org/structure/8ZSN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSO", "url": "https://www.rcsb.org/structure/8ZSO", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSQ", "url": "https://www.rcsb.org/structure/8ZSQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSR", "url": "https://www.rcsb.org/structure/8ZSR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZXZ", "url": "https://www.rcsb.org/structure/8ZXZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CE2", "url": "https://www.rcsb.org/structure/9CE2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9J6H", "url": "https://www.rcsb.org/structure/9J6H", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9J6W", "url": "https://www.rcsb.org/structure/9J6W", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00346", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00346", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29091", "url": "https://www.rhea-db.org/rhea/29091", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F811", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F811", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F811-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F811-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8I2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1A8", "url": "https://www.uniprot.org/uniprotkb/F1S1A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1A8-1", "url": "https://www.uniprot.org/uniprotkb/F1S1A8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "FRPMAALRALCSLRGVAAQVLRPGAGARLPIQPSRGARQWQPDVEWAEQFGGAVMYPTKETAHWKPPPWNDVDPPKDTLVSNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRLLNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGLLDDIYEFSKNFSFRIDELEEMLTNNRIWRNRTVDIGVVTAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSLRIISQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR", "length": 466, "header": "tr|A0A5G2R3N7-1|A0A5G2R3N7_PIG Isoform 1 of NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Sus scrofa OX=9823 GN=NDUFS2 PE=1 SV=1 CANONICAL=A0A5G2R3N7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R3N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7/entry#A0A5G2R3N7-1", "sequence": { "sequence": "FRPMAALRALCSLRGVAAQVLRPGAGARLPIQPSRGARQWQPDVEWAEQFGGAVMYPTKETAHWKPPPWNDVDPPKDTLVSNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRLLNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGLLDDIYEFSKNFSFRIDELEEMLTNNRIWRNRTVDIGVVTAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSLRIISQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR", "length": 466, "header": "tr|A0A5G2R3N7-1|A0A5G2R3N7_PIG Isoform 1 of NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Sus scrofa OX=9823 GN=NDUFS2 PE=1 SV=1 CANONICAL=A0A5G2R3N7-1" }, "locus": { "chromosome": "4", "start_pos": 89257083, "end_pos": 89247153, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066655.1", "url": "https://www.ensembl.org/id/ENSSSCT00000066655.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071701.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071701.1" } ] } }, { "isoform_ac": "A0A8W4F811-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7/entry#A0A8W4F811-1", "sequence": { "sequence": "MAALRALCSLRGVAAQVLRPGAGARLPIQPSRGARQWQPDVEWAEQFGGAVMYPTKETAHWKPPPWNDVDPPKDTLVSNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRLLNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYIRPGGVHQMLTNNRIWRNRTVDIGVVTAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSLRIISQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR", "length": 437, "header": "tr|A0A8W4F811-1|A0A5G2R3N7_PIG Computationally mapped isoform of NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Sus scrofa OX=9823 GN=NDUFS2 PE=1 SV=1 CANONICAL=A0A5G2R3N7-1" }, "locus": { "chromosome": "4", "start_pos": 89257042, "end_pos": 89247153, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106627.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106627.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074929.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074929.1" } ] } }, { "isoform_ac": "A0A8W4F8I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7/entry#A0A8W4F8I2-1", "sequence": { "sequence": "MAALRALCSLRGVAAQVLRPGAGARLPIQPSRGARQWQPDVEWAEQFGGAVMYPTKETAHWKPPPWNDVDPPKDTLVSNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRLLNHIMAVTTHALDIGAMTPFFWMFEEREKDLPLGLLDDIYEFSKNFSFRIDELEEMLTNNRIWRNRTVDIGVVTAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSLRIISQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR", "length": 438, "header": "tr|A0A8W4F8I2-1|A0A5G2R3N7_PIG Computationally mapped isoform of NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Sus scrofa OX=9823 GN=NDUFS2 PE=1 SV=1 CANONICAL=A0A5G2R3N7-1" }, "locus": { "chromosome": "4", "start_pos": 89257042, "end_pos": 89247153, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099556.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099556.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075125.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075125.1" } ] } }, { "isoform_ac": "F1S1A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7/entry#F1S1A8-1", "sequence": { "sequence": "SLWRGKMAALRALCSLRGVAAQVLRPGAGARLPIQPSRGARQWQPDVEWAEQFGGAVMYPTKETAHWKPPPWNDVDPPKDTLVSNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRLLNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGLLDDIYEFSKNFSFRIDELEEMLTNNRIWRNRTVDIGVVTAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSLRIISQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR", "length": 469, "header": "tr|F1S1A8-1|A0A5G2R3N7_PIG Computationally mapped isoform of NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Sus scrofa OX=9823 GN=NDUFS2 PE=1 SV=3 CANONICAL=A0A5G2R3N7-1" }, "locus": { "chromosome": "4", "start_pos": 89257060, "end_pos": 89247153, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006967.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006967.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006777.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006777.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The architecture of the mammalian respirasome.", "journal": "Nature", "date": "2016", "authors": "Gu Jinke, Wu Meng, Guo Runyu, Yan Kaige, Lei Jianlin, Gao Ning, Yang Maojun", "evidence": [ { "database": "UniProtKB", "id": "F1S1A8", "url": "https://www.uniprot.org/uniprotkb/F1S1A8" } ], "reference": [ { "type": "PubMed", "id": "27654917", "url": "https://glygen.org/publication/PubMed/27654917" } ] }, { "title": "Structure of Mammalian Respiratory Supercomplex I1III2IV1.", "journal": "Cell", "date": "2016", "authors": "Wu Meng, Gu Jinke, Guo Runyu, Huang Yushen, Yang Maojun", "evidence": [ { "database": "UniProtKB", "id": "F1S1A8", "url": "https://www.uniprot.org/uniprotkb/F1S1A8" } ], "reference": [ { "type": "PubMed", "id": "27912063", "url": "https://glygen.org/publication/PubMed/27912063" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1A8", "url": "https://www.uniprot.org/uniprotkb/F1S1A8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "The coupling mechanism of mammalian mitochondrial complex I.", "journal": "Nat. Struct. Mol. Biol.", "date": "2022", "authors": "Gu Jinke, Liu Tianya, Guo Runyu, Zhang Laixing, Yang Maojun", "evidence": [ { "database": "UniProtKB", "id": "F1S1A8", "url": "https://www.uniprot.org/uniprotkb/F1S1A8" } ], "reference": [ { "type": "PubMed", "id": "35145322", "url": "https://glygen.org/publication/PubMed/35145322" } ] } ], "pathway": [ { "id": "R-SSC-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-SSC-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "NADH dehydrogenase (ubiquinone) activity", "id": "GO:0008137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008137", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "quinone binding", "id": "GO:0048038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048038", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on NAD(P)H", "id": "GO:0016651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016651", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "NADH dehydrogenase activity", "id": "GO:0003954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003954", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "oxygen sensor activity", "id": "GO:0019826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019826", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "mitochondrial electron transport, NADH to ubiquinone", "id": "GO:0006120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006120", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "gliogenesis", "id": "GO:0042063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042063", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "neural precursor cell proliferation", "id": "GO:0061351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" }, { "name": "cellular response to oxygen levels", "id": "GO:0071453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071453", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3N7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29091", "name": "", "equation": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29091", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29091" } ] }, { "id": "R-SSC-163217", "name": "Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [ "R-ALL-73663" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-163217", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163217" } ] }, { "id": "R-SSC-6788523", "name": "NUBPL transfers 4Fe-4S to Complex I subunits", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6788523", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6788523" } ] }, { "id": "R-SSC-6799179", "name": "Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6799179", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799179" } ] }, { "id": "R-SSC-6799191", "name": "Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6799191", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799191" } ] }, { "id": "R-SSC-6799196", "name": "The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6799196", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799196" } ] }, { "id": "R-SSC-6799202", "name": "The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6799202", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799202" } ] }, { "id": "R-SSC-6799203", "name": "IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6799203", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799203" } ] }, { "id": "R-SSC-6800868", "name": "NDUF subunits bind to form the IP subcomplex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6800868", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6800868" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-73663", "participant_name": "CoQ [mitochondrial inner membrane]", "crossref": [ { "id": "46245", "database": "ChEBI", "url": "" }, { "id": "C11378", "database": "COMPOUND", "url": "" }, { "id": "ZINC000085427689", "database": "ZINC", "url": "" }, { "id": "HMDB0001072", "database": "HMDB Metabolite", "url": "" }, { "id": "C00399", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R3N7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 466, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R3N7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3N7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R3N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N7" }, { "id": "PF00346", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00346" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NADH-quinone oxidoreductase subunit D", "eco_id": "ECO_0000259", "start_pos": 196, "end_pos": 466, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 253, "end_pos": 255 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R661-1", "uniprot_ac": "A0A5G2R661", "uniprot_id": "A0A5G2R661_PIG", "mass": { "chemical_mass": 128768.0, "monoisotopic_mass": 128768.0 }, "refseq": {}, "gene_names": [ { "name": "ARHGEF9", "type": "recommended", "evidence": [ { "id": "A0A5G2R661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 9", "type": "recommended", "evidence": [ { "id": "A0A5G2R661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661/entry#names_and_taxonomy" } ] }, { "name": "Collybistin", "type": "synonym", "evidence": [ { "id": "A0A5G2R661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661/entry#names_and_taxonomy" } ] }, { "name": "Rac/Cdc42 guanine nucleotide exchange factor 9", "type": "synonym", "evidence": [ { "id": "A0A5G2R661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.", "evidence": [ { "database": "UniProtKB", "id": "K7GP42", "url": "https://www.uniprot.org/uniprotkb/K7GP42#function" }, { "database": "UniProtKB", "id": "ARBA00043844", "url": "https://www.uniprot.org/uniprotkb/ARBA00043844#function" }, { "database": "UniProtKB", "id": "A0A286ZK59", "url": "https://www.uniprot.org/uniprotkb/A0A286ZK59#function" }, { "database": "UniProtKB", "id": "A0A5G2R661", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661#function" }, { "database": "UniProtKB", "id": "A0A8W4FD14", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FD14#function" }, { "database": "UniProtKB", "id": "K7GNZ4", "url": "https://www.uniprot.org/uniprotkb/K7GNZ4#function" }, { "database": "UniProtKB", "id": "F1RTP2", "url": "https://www.uniprot.org/uniprotkb/F1RTP2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R661", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARHGEF9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661", "locus": {} } ], "crossref": [ { "id": "A0A5G2R661", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R661", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012362", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012362", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11975", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11975", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512575", "url": "https://www.ncbi.nlm.nih.gov/gene/100512575", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035728", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035728", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512575", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512575", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZK59", "url": "https://www.orthodb.org/?gene=A0A286ZK59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1RTP2", "url": "https://www.orthodb.org/?gene=F1RTP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47544", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47544", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47544:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47544:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-977443", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-977443", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZK59", "url": "https://www.uniprot.org/uniprotkb/A0A286ZK59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZK59-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZK59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A9U3", "url": "https://www.uniprot.org/uniprotkb/A0A287A9U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A9U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A9U3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R661", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R661-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FD14", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FD14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FD14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FD14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTP2", "url": "https://www.uniprot.org/uniprotkb/F1RTP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTP2-1", "url": "https://www.uniprot.org/uniprotkb/F1RTP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GNZ4", "url": "https://www.uniprot.org/uniprotkb/K7GNZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GNZ4-1", "url": "https://www.uniprot.org/uniprotkb/K7GNZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GP42", "url": "https://www.uniprot.org/uniprotkb/K7GP42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GP42-1", "url": "https://www.uniprot.org/uniprotkb/K7GP42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METLSSCQTAFLSELMPNGYLAQIFPGHPGVNGLAVKVGLEQPERCDQSDLSPRKENGQNKKKTKVNKIWNFVSRRKGASSQGKRPQSMILLEDTSRPSELKSKVTLMDRMKSFKRLKPPTGACKNTLPRSNKAQEPQEVPGTYHMRKAEEAPKPFRYSYSGHIESLEPFLADVQRLVHVPKRVNQKELAFDDTGIQLEEDCWGKESPEQHSRGRQARSYQKSMFPGEDEAPCTLAGDNRIQELEASIEASTLEGKMERNYEESPVHSRRDKTVPFGSVVKFFNNMAEVARKWRAFPREELQMGRHHGEAYFISGGSEGIILEGTASRTSFSLNLPSQPPKAALWGSVIGRHQHHHHKDSQASCTFEMSIEGKETLGNALAGPCNATALTTTSAACKFQDNLTPENGCSCHYSHAFTREHSSSEELNEDTETVVSFPKEDDSARMSPELGTCARNVTTKAVMEKLEKPNELKESETHRGPEEPIQAGKPQDSDLDMITTDAEREASKVCTGVLGTQVFFPPDEPSPRTPPLKILLEKCHSLPISKGIPRELDQVSWRRFRKICTDNLNQRSKTLETYKNITGYLNPQGPGTKYVNELITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDGVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKVPKQKVHIHYVVHLNTMQGVNAGRSVPPSYPPPQDPLNQGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK", "length": 1122, "header": "tr|A0A5G2R661-1|A0A5G2R661_PIG Isoform 1 of Rho guanine nucleotide exchange factor 9 OS=Sus scrofa OX=9823 GN=ARHGEF9 PE=1 SV=2 CANONICAL=A0A5G2R661-1" }, "isoforms": [ { "isoform_ac": "A0A286ZK59-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661/entry#A0A286ZK59-1", "sequence": { "sequence": "METLSSCQTAFLSELMPNGYLAQIFPGHPGVNGLAVKVGLEQPERCDQSDLSPRKENGQNKKKTKVNKIWNFVSRRKGASSQGKRPQSMILLEDTSRPSELKSKVTLMDRMKSFKRLKPPTGACKNTLPRSNKAQEPQEVPGTYHMRKAEEAPKPFRYSYSGHIESLEPFLADVQRLVHVPKRVNQKELAFDDTGIQLEEDCWGKESPEQHSRGRQARSYQKSMFPGEDEAPCTLAGDNRIQELEASIEASTLEGKMERNYEESPVHSRRDKTVPFGSVVKFFNNMAEVARKWRAFPREELQMGRHHGEAYFISGGSEGIILEGTASRTSFSLNLPSQPPKAALWGSVIGRHQHHHHKDSQASCTFEMSIEGKETLGNALAGPCNATALTTTSAACKFQDNLTPENGCSCHYSHAFTREHSSSEELNEDTETVVSFPKEDDSARMSPELGTCARNVTTKAVMEKLEKPNELKESETHRGPEEPIQAGKPQDSDLDMITTDAEREASKVCTGVLGTQVFFPPDEPSPRTPPLKILLEKCHSLPISKGIPRELDQVSWRRFRKICTDNLNQRSKTLETYKNITGYLNPQGPGTKYVNELITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDGVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKVPKQKGVNAGRSVPPSYPPPQDPLNQGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK", "length": 1109, "header": "tr|A0A286ZK59-1|A0A5G2R661_PIG Computationally mapped isoform of Rho guanine nucleotide exchange factor 9 OS=Sus scrofa OX=9823 GN=ARHGEF9 PE=1 SV=2 CANONICAL=A0A5G2R661-1" }, "locus": { "chromosome": "X", "start_pos": 50450857, "end_pos": 50163031, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049269.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049269.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031856.2", "url": "https://www.ensembl.org/id/ENSSSCP00000031856.2" } ] } }, { "isoform_ac": "A0A287A9U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661/entry#A0A287A9U3-1", "sequence": { "sequence": "METLSSCQTAFLSELMPNGYLAQIFPGHPGVNGLAVKVGLEQPERCDQSDLSPRKENGQNKKKTKVNKIWNFVSRRKGASSQGKRPQSMILLEDTSRPSELKSKVTLMDRMKSFKRLKPPTGACKNTLPRSNKAQEPQEVPGTYHMRKAEEAPKPFRYSYSGHIESLEPFLADVQRLVHVPKRVNQKELAFDDTGIQLEEDCWGKESPEQHSRGRQARSYQKSMFPGEDEAPCTLAGDNRIQELEASIEASTLEGKMERNYEESPVHSRRDKTVPFGSVVKFFNNMAEVARKWRAFPREELQMGRHHGEAYFISGGSEGIILEGTASRTSFSLNLPSQPPKAALWGSVIGRHQHHHHKDSQASCTFEMSIEGKETLGNALAGPCNATALTTTSAACKFQDNLTPENGCSCHYSHAFTREHSSSEELNEDTETVVSFPKEDDSARMSPELGTCARNVTTKAVMEKLEKPNELKESETHRGPEEPIQAGKPQDSDLDMITTDAEREASKVCTGVLGTQVFFPPDEPSPRTPPLKILLEKCHSLPISKGIPRELDQVSWRRFRKICTDNLNQRSKTLETYKNITGYLNPQGPGTKYVNELWVNQEDGVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKVPKQKGVNAGRSVPPSYPPPQDPLNQGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK", "length": 1049, "header": "tr|A0A287A9U3-1|A0A5G2R661_PIG Computationally mapped isoform of Rho guanine nucleotide exchange factor 9 OS=Sus scrofa OX=9823 GN=ARHGEF9 PE=1 SV=2 CANONICAL=A0A5G2R661-1" }, "locus": { "chromosome": "X", "start_pos": 50450857, "end_pos": 50163031, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045688.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045688.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040564.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040564.2" } ] } }, { "isoform_ac": "A0A5G2R661-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661/entry#A0A5G2R661-1", "sequence": { "sequence": "METLSSCQTAFLSELMPNGYLAQIFPGHPGVNGLAVKVGLEQPERCDQSDLSPRKENGQNKKKTKVNKIWNFVSRRKGASSQGKRPQSMILLEDTSRPSELKSKVTLMDRMKSFKRLKPPTGACKNTLPRSNKAQEPQEVPGTYHMRKAEEAPKPFRYSYSGHIESLEPFLADVQRLVHVPKRVNQKELAFDDTGIQLEEDCWGKESPEQHSRGRQARSYQKSMFPGEDEAPCTLAGDNRIQELEASIEASTLEGKMERNYEESPVHSRRDKTVPFGSVVKFFNNMAEVARKWRAFPREELQMGRHHGEAYFISGGSEGIILEGTASRTSFSLNLPSQPPKAALWGSVIGRHQHHHHKDSQASCTFEMSIEGKETLGNALAGPCNATALTTTSAACKFQDNLTPENGCSCHYSHAFTREHSSSEELNEDTETVVSFPKEDDSARMSPELGTCARNVTTKAVMEKLEKPNELKESETHRGPEEPIQAGKPQDSDLDMITTDAEREASKVCTGVLGTQVFFPPDEPSPRTPPLKILLEKCHSLPISKGIPRELDQVSWRRFRKICTDNLNQRSKTLETYKNITGYLNPQGPGTKYVNELITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDGVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKVPKQKVHIHYVVHLNTMQGVNAGRSVPPSYPPPQDPLNQGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK", "length": 1122, "header": "tr|A0A5G2R661-1|A0A5G2R661_PIG Isoform 1 of Rho guanine nucleotide exchange factor 9 OS=Sus scrofa OX=9823 GN=ARHGEF9 PE=1 SV=2 CANONICAL=A0A5G2R661-1" }, "locus": { "chromosome": "X", "start_pos": 50450857, "end_pos": 50163031, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071442.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071442.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072574.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072574.2" } ] } }, { "isoform_ac": "A0A8W4FD14-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661/entry#A0A8W4FD14-1", "sequence": { "sequence": "MTLLITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDGVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKVPKQKGVNAGRSVPPSYPPPQDPLNQGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK", "length": 472, "header": "tr|A0A8W4FD14-1|A0A5G2R661_PIG Computationally mapped isoform of Rho guanine nucleotide exchange factor 9 OS=Sus scrofa OX=9823 GN=ARHGEF9 PE=1 SV=1 CANONICAL=A0A5G2R661-1" }, "locus": { "chromosome": "X", "start_pos": 50302764, "end_pos": 50163031, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098348.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098348.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076199.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076199.1" } ] } }, { "isoform_ac": "F1RTP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661/entry#F1RTP2-1", "sequence": { "sequence": "MQWIRGGSGMLITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDGVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKVPKQKGVNAGRSVPPSYPPPQDPLNQGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK", "length": 523, "header": "tr|F1RTP2-1|A0A5G2R661_PIG Computationally mapped isoform of Rho guanine nucleotide exchange factor 9 OS=Sus scrofa OX=9823 GN=ARHGEF9 PE=1 SV=4 CANONICAL=A0A5G2R661-1" }, "locus": { "chromosome": "X", "start_pos": 50336177, "end_pos": 50163031, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013519.4", "url": "https://www.ensembl.org/id/ENSSSCT00000013519.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013157.4", "url": "https://www.ensembl.org/id/ENSSSCP00000013157.4" } ] } }, { "isoform_ac": "K7GNZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661/entry#K7GNZ4-1", "sequence": { "sequence": "MDSLTEQRLTSPNLPLFRTLALISSREPPGKNKIKRDRQRQGKRGRERTSFLTQGGKRFELQHGLAVICMTLLITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDGVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKVPKQKGKTAFNYNLPDPTHSCETEKPLAMYLYIPRLIFILKFTRGGGKCPDTQVSLMTSGK", "length": 581, "header": "tr|K7GNZ4-1|A0A5G2R661_PIG Computationally mapped isoform of Rho guanine nucleotide exchange factor 9 OS=Sus scrofa OX=9823 GN=ARHGEF9 PE=1 SV=4 CANONICAL=A0A5G2R661-1" }, "locus": { "chromosome": "X", "start_pos": 50303126, "end_pos": 50183272, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033580.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033580.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029601.4", "url": "https://www.ensembl.org/id/ENSSSCP00000029601.4" } ] } }, { "isoform_ac": "K7GP42-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661/entry#K7GP42-1", "sequence": { "sequence": "MTLLITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDGVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGVNAGRSVPPSYPPPQDPLNQGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK", "length": 493, "header": "tr|K7GP42-1|A0A5G2R661_PIG Computationally mapped isoform of Rho guanine nucleotide exchange factor 9 OS=Sus scrofa OX=9823 GN=ARHGEF9 PE=1 SV=4 CANONICAL=A0A5G2R661-1" }, "locus": { "chromosome": "X", "start_pos": 50302764, "end_pos": 50163031, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033226.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033226.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029652.4", "url": "https://www.ensembl.org/id/ENSSSCP00000029652.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZK59", "url": "https://www.uniprot.org/uniprotkb/A0A286ZK59" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512575", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512575", "resource": "KEGG Pathway" }, { "id": "R-SSC-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-SSC-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-SSC-977443", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-977443", "resource": "Reactome", "description": "GABA receptor activation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R661", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R661", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R661", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R661", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661" } ], "pmid": "" }, { "name": "postsynaptic specialization", "id": "GO:0099572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099572", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R661", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R661", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of postsynaptic specialization assembly", "id": "GO:0099150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099150", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R661", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1113, "end_pos": 1115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 579, "end_pos": 581, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" }, { "start_pos": 978, "end_pos": 980, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R661-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1122, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R661-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R661" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 696, "end_pos": 880, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 911, "end_pos": 1018, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R661" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 601, "end_pos": 660, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1113, "end_pos": 1115 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 579, "end_pos": 581 }, { "start_pos": 872, "end_pos": 874 }, { "start_pos": 978, "end_pos": 980 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R212-1", "uniprot_ac": "A0A5G2R212", "uniprot_id": "A0A5G2R212_PIG", "mass": { "chemical_mass": 75333.0, "monoisotopic_mass": 75333.0 }, "refseq": {}, "gene_names": [ { "name": "COQ8A", "type": "recommended", "evidence": [ { "id": "A0A5G2R212", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212" } ] } ], "protein_names": [ { "name": "Atypical kinase COQ8A, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A5G2R212", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212/entry#names_and_taxonomy" } ] }, { "name": "Chaperone activity of bc1 complex-like", "type": "synonym", "evidence": [ { "id": "A0A5G2R212", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212/entry#names_and_taxonomy" } ] }, { "name": "Coenzyme Q protein 8A", "type": "synonym", "evidence": [ { "id": "A0A5G2R212", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212/entry#names_and_taxonomy" } ] }, { "name": "aarF domain-containing protein kinase 3", "type": "synonym", "evidence": [ { "id": "A0A5G2R212", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is still unclear: may act as a protein kinase that mediates phosphorylation of COQ3. According to other reports, acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates. However, the small molecule kinase activity was not confirmed by another publication. Shows an unusual selectivity for binding ADP over ATP.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R212", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212#function" }, { "database": "UniProtKB", "id": "ARBA00058956", "url": "https://www.uniprot.org/uniprotkb/ARBA00058956#function" }, { "database": "UniProtKB", "id": "A0A286ZK64", "url": "https://www.uniprot.org/uniprotkb/A0A286ZK64#function" }, { "database": "UniProtKB", "id": "A0A287BEB5", "url": "https://www.uniprot.org/uniprotkb/A0A287BEB5#function" }, { "database": "UniProtKB", "id": "A0A287AZ56", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ56#function" }, { "database": "UniProtKB", "id": "A0A287B895", "url": "https://www.uniprot.org/uniprotkb/A0A287B895#function" }, { "database": "UniProtKB", "id": "A0A8W4FKC9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKC9#function" }, { "database": "UniProtKB", "id": "F1S8Q4", "url": "https://www.uniprot.org/uniprotkb/F1S8Q4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R212", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "COQ8A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212", "locus": { "chromosome": "10", "start_pos": 14643772, "end_pos": 14596599, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010861", "url": "https://www.ensembl.org/id/ENSSSCG00000010861" } ] } } ], "crossref": [ { "id": "A0A5G2R212", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R212", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010861", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010861", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13970", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13970", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100511399", "url": "https://www.ncbi.nlm.nih.gov/gene/100511399", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511399", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511399", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PEYYVPR", "url": "https://omabrowser.org/oma/group/PEYYVPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZK64", "url": "https://www.orthodb.org/?gene=A0A286ZK64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43851", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43851", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43851:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43851:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03109", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03109", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2142789", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2142789", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZK64", "url": "https://www.uniprot.org/uniprotkb/A0A286ZK64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZK64-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZK64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AZ56", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AZ56-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B895", "url": "https://www.uniprot.org/uniprotkb/A0A287B895", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B895-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B895-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BEB5", "url": "https://www.uniprot.org/uniprotkb/A0A287BEB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BEB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BEB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R212", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R212-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKC9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S8Q4", "url": "https://www.uniprot.org/uniprotkb/F1S8Q4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S8Q4-1", "url": "https://www.uniprot.org/uniprotkb/F1S8Q4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVLGDALMLVKGLVKLTQAAVETHLQHLGLGGELVLLARTLQSTAAEQMGVIWGQVQGQERHEEPHSESFDDPQAEFHFSGPRVEDFSAAASSEQAQDHTSSQGPAPAYAASGPFREGGFPGQAAHPLGGVNRRLFADPRDPFSSTGLQRRFLHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPEDPSGKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMVRRGGRRAALGAGVGVLGGFSGGPRPCSWPPPGISLQKTLNKDLGPSWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHRVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYRRRQAEQQ", "length": 677, "header": "tr|A0A5G2R212-1|A0A5G2R212_PIG Isoform 1 of Atypical kinase COQ8A, mitochondrial OS=Sus scrofa OX=9823 GN=COQ8A PE=1 SV=1 CANONICAL=A0A5G2R212-1" }, "isoforms": [ { "isoform_ac": "A0A286ZK64-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212/entry#A0A286ZK64-1", "sequence": { "sequence": "MAAVLGDALMLVKGLVKLTQAAVETHLQHLGLGGELVLLARTLQSTAAEQMGVIWGQVQGQERHEEPHSESFDDPQAEFHFSGPRVEDFSAAASSEQAQDHTSSQGPAPAYAASGPFREGGFPGQAAHPLGGVNRRLFADPRDPFSSTGLQRRFLHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPEDPSGKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNKDLGPSWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHRVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYRRRQAEQQ", "length": 640, "header": "tr|A0A286ZK64-1|A0A5G2R212_PIG Computationally mapped isoform of Atypical kinase COQ8A, mitochondrial OS=Sus scrofa OX=9823 GN=COQ8A PE=1 SV=1 CANONICAL=A0A5G2R212-1" }, "locus": { "chromosome": "10", "start_pos": 14642618, "end_pos": 14619633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054103.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054103.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031852.1", "url": "https://www.ensembl.org/id/ENSSSCP00000031852.1" } ] } }, { "isoform_ac": "A0A287AZ56-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212/entry#A0A287AZ56-1", "sequence": { "sequence": "MAAVLGDALMLVKGLVKLTQAAVETHLQHLGLGGELVLLARTLQSTAAEQMGVIWGQVQGQERHEEPHSESFDDPQAEFHFSGPRVEDFSAAASSEQAQDHTSSQGPAPAYAASGPFREGGFPGQAAHPLGGVNRRLFADPRDPFSSTGLQRRFLHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPEDPSDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNKDLGPSWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHRVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYRRRQAEQQ", "length": 599, "header": "tr|A0A287AZ56-1|A0A5G2R212_PIG Computationally mapped isoform of Atypical kinase COQ8A, mitochondrial OS=Sus scrofa OX=9823 GN=COQ8A PE=1 SV=1 CANONICAL=A0A5G2R212-1" }, "locus": { "chromosome": "10", "start_pos": 14642618, "end_pos": 14619633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050670.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050670.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049243.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049243.2" } ] } }, { "isoform_ac": "A0A287B895-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212/entry#A0A287B895-1", "sequence": { "sequence": "MAAVLGDALMLVKGLVKLTQAAVETHLQHLGLGGELVLLARTLQSTAAEQMGVIWGQVQGQERHEEPHSESFDDPQAEFHFSGPRVEDFSAAASSEQAQDHTSSQAAHPLGGVNRRLFADPRDPFSSTGLQRRFLHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPEDPSGKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNKDLGPSWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHRVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYRRRQAEQQ", "length": 620, "header": "tr|A0A287B895-1|A0A5G2R212_PIG Computationally mapped isoform of Atypical kinase COQ8A, mitochondrial OS=Sus scrofa OX=9823 GN=COQ8A PE=1 SV=2 CANONICAL=A0A5G2R212-1" }, "locus": { "chromosome": "10", "start_pos": 14642618, "end_pos": 14619633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054257.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054257.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052336.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052336.2" } ] } }, { "isoform_ac": "A0A287BEB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212/entry#A0A287BEB5-1", "sequence": { "sequence": "MAAVLGDALMLVKGLVKLTQAAVETHLQHLGLGGELVLLARTLQSTAAEQMGVIWGQVQGQERHEEPHSESFDDPQAEFHFSGPRVEDFSAAASSEQAQDHTSSQGPAAHPLGGVNRRLFADPRDPFSSTGLQRRFLHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPEDPSGKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNKDLGPSWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHRVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYRRRQAEQQ", "length": 622, "header": "tr|A0A287BEB5-1|A0A5G2R212_PIG Computationally mapped isoform of Atypical kinase COQ8A, mitochondrial OS=Sus scrofa OX=9823 GN=COQ8A PE=1 SV=2 CANONICAL=A0A5G2R212-1" }, "locus": { "chromosome": "10", "start_pos": 14642618, "end_pos": 14619633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051518.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051518.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054437.2", "url": "https://www.ensembl.org/id/ENSSSCP00000054437.2" } ] } }, { "isoform_ac": "A0A5G2R212-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212/entry#A0A5G2R212-1", "sequence": { "sequence": "MAAVLGDALMLVKGLVKLTQAAVETHLQHLGLGGELVLLARTLQSTAAEQMGVIWGQVQGQERHEEPHSESFDDPQAEFHFSGPRVEDFSAAASSEQAQDHTSSQGPAPAYAASGPFREGGFPGQAAHPLGGVNRRLFADPRDPFSSTGLQRRFLHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPEDPSGKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMVRRGGRRAALGAGVGVLGGFSGGPRPCSWPPPGISLQKTLNKDLGPSWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHRVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYRRRQAEQQ", "length": 677, "header": "tr|A0A5G2R212-1|A0A5G2R212_PIG Isoform 1 of Atypical kinase COQ8A, mitochondrial OS=Sus scrofa OX=9823 GN=COQ8A PE=1 SV=1 CANONICAL=A0A5G2R212-1" }, "locus": { "chromosome": "10", "start_pos": 14642618, "end_pos": 14619633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086305.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086305.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068232.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068232.1" } ] } }, { "isoform_ac": "A0A8W4FKC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212/entry#A0A8W4FKC9-1", "sequence": { "sequence": "MAAVLGDALMLVKGLVKLTQAAVETHLQHLGLGGELVLLARTLQSTAAEQMGVIWGQVQGQERHEEPHSESFDDPQAEFHFSGPRVEDFSAAASSEQAQDHTSSQGPAPAYAASGPFREGGFPGQAAHPLGGVNRRLFADPRDPFSSTGLQRRFLHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPEDPSGRPLCSASSPGLPGRGAAVAPVPSFRGVDDAFINPHLAKIFERVRQSADFMPLKQMMVRRGGRRAALGAGVGVLGGFSGGPRPCSWPPPGISLQKTLNKDLGPSWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHRVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYRRRQAEQQ", "length": 664, "header": "tr|A0A8W4FKC9-1|A0A5G2R212_PIG Computationally mapped isoform of Atypical kinase COQ8A, mitochondrial OS=Sus scrofa OX=9823 GN=COQ8A PE=1 SV=1 CANONICAL=A0A5G2R212-1" }, "locus": { "chromosome": "10", "start_pos": 14642618, "end_pos": 14619633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099360.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099360.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078760.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078760.1" } ] } }, { "isoform_ac": "F1S8Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212/entry#F1S8Q4-1", "sequence": { "sequence": "MAAVLGDALMLVKGLVKLTQAAVETHLQHLGLGGELVLLARTLQSTAAEQMGVIWGQVQGQERHEEPHSESFDDPQAEFHFSGPRVEDFSAAASSEQAQDHTSSQGPAAHPLGGVNRRLFADPRDPFSSTGLQRRFLHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPEDPSGKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNKDLGPSWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHRVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKGGWVLCTLFL", "length": 537, "header": "tr|F1S8Q4-1|F1S8Q4_PIG Computationally mapped isoform of Atypical kinase COQ8A, mitochondrial OS=Sus scrofa OX=9823 GN=COQ8A PE=1 SV=4 CANONICAL=A0A5G2R212-1" }, "locus": { "chromosome": "10", "start_pos": 14641376, "end_pos": 14619633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011883.4", "url": "https://www.ensembl.org/id/ENSSSCT00000011883.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011579.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011579.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZK64", "url": "https://www.uniprot.org/uniprotkb/A0A286ZK64" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511399", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511399", "resource": "KEGG Pathway" }, { "id": "R-SSC-2142789", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2142789", "resource": "Reactome", "description": "Ubiquinol biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NGM2-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "COQ8A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGDAIMVMRGLTKLSKAVLETQAGQLRQVILGGDAVTIAKSLQATAEEQFSSALGKMQELGKQQENLSDFSEDFGKDYDFLAQEPPDASRDFSTAPSKPHEHSSEGPAYSYTTNGPFKSVGETGDSGLGQKPFPPKMDAKLFGGFRDPGNPFAAVFGQNRAFHQDHSSVGGLTAEDIDKARQAKTEQKPYKQMLSERARERKVPVTRIGRLANFGGLAVGLGIGALAEVAKKSLRPEERSGKKAVMDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLQRIFERVRQSADFMPIKQMMKTLNNDLGPNWRDKLESFEERPFAAASIGQVHLARLKNGKEVAMKIQYPGVAQSINSDVNNLMTVLSMSNILPEGLFPEHLIEVLSRELALECDYQREAACAKKFQELLKDHPFFYVPRVVDELCSKHVLTTELVSGFPLDQAVGLSQEIRNEICHNILVLCLRELFEFRYMQTDPNWSNFFYDPQLHKVALLDFGATRGFDEKFTDVYIEVIKAAADMDRERVLKKSIEMKFLTGYEVKEMEDAHLNAVLILGEAFASEEPFDFGNQSTTEKIHGLIPVMLKHRLVPPPEETYSLHRKMGGSFLICTKLKAKIPCKNMFEEAYSKYWSNRGKKPED", "length": 648 }, "evidence": [ { "id": "A0A5G2R212", "url": "https://omabrowser.org/oma/group/A0A5G2R212/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HV77-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "Coq8a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAMLGDAIMVAKGLAKLTQAAVETHLQNLGLGGELILAARALQSTAVEQISMVFGKVQGQDKHEDLYATENFEDLEAEVQFSTPQAAETSLDFSATSSPDQSLSSSLGHAHSEGPAPTYVSSGPFREAGLSGQATSPMGRVNGRLFVNTRDLFLASGIQRRFFHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPENSTGKKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNNDLGPHWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELVLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELITGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPVMLKHRLIPPPEETYSLHRKMGGSFLICSKLKARFPCKTMFEEAYSNYCRMKSGLQ", "length": 649 }, "evidence": [ { "id": "A0A5G2R212", "url": "https://omabrowser.org/oma/group/A0A5G2R212/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P27697-1", "protein_name": "Atypical kinase COQ8, mitochondrial", "gene_name": "COQ8", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVTNMVKLRNLRRLYCSSRLLRTIQNGRISSVSSISLSKKYTTKSAKEGEENVERKHEEEKKDTLKSSSVPTSRISRLFHYGSLAAGVGMNAAAKGISEVAKGNSPTWKSLILSDSNIDRITNKFSKMRGVALKIGQLLSFQDEKVLPKELYEILSRVQNSANHMPQRQLEKVMAKELGANWKTKFSKFDKIPMAAASIGQVHAAELPSGQRVVVKIQYPGVKESIDSDLNSLLMLLTASSLLPKGLFLDKTIANARTELKWECDYNREARALQKFEALLKDDPAFEVPHVFPEYTTDNIITMTRMEGTEIMKLPKASQETKNFISENIMRLCLEEIATFKYMQTDPNWANFLYNGRTKKIELLDFGASRPFAEDFILKYRKLLTYATLRDRKGAYEMSVQLGYLTGLESQSMKDAHVDSVLTLGEPFRGDVDKSFDFKDQTVSDRIRGNIGLMLNERLCPPPEETYSLHRKFSGIFLLCARMGASVHCAKLFKEIFAYKV", "length": 501 }, "evidence": [ { "id": "A0A5G2R212", "url": "https://omabrowser.org/oma/group/A0A5G2R212/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q29RI0-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "COQ8A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAMLGDAIMLIKGFVKLTQAAVETHLQHLGLSGELLMAVRALQSTATEQVGMVFGQVQGQETPEEYYSESLDDPEGAFHFSGMRAESASADVSAASSPEQSPPPWAHAAGSEGPAPAYVASAPFREGGVLGQAASPLGRVNGRLFASPRDPFSAPGLQRRVYHQDQSSMGGLTAEDIEKARQAKARPESKPHKQALSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPDDPSGKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFDRVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARLKGGREVAMKIQYPGVAQSINSDVNNLMTVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARRFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFQFMQTDPNWSNFFYDPELHKVALLDFGATREFDRSFTDLYIQIIRAAANQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCRRQAEQQ", "length": 648 }, "evidence": [ { "id": "A0A5G2R212", "url": "https://omabrowser.org/oma/group/A0A5G2R212/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54IH6-1", "protein_name": "Probable serine/threonine-protein kinase abkA", "gene_name": "abkA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGGRLNDLIQVAYGGKNVILSMMKNKTRQTSSVFINNLNSLNNNNNNISLKDKFKDLKDLKDNLNEKKINNDNDDDDEDNLIFDEKKDFLNENKNPELNYIKSKGHKIPSSQTSRFWEFTKLAVGVGAGFLGEKTKRTIDSSSSSSSPSSSYSAIFTDTNAERMAESFSRMRGAALKIGQVLSIQDESFLPPKFVEILDRVRKNANPIPLEQLYNTMSNELGENWRSKFQLFQDDPIAAASIGQVHRAITLDGKEVAVKVQYPGVADSITSDIKNLSSLLKMIVPETAYIEKSLESARSELLLETDYLNEASNQLKFKSLLESSINSGTNGSFKYLKDLYVPNVIMELTTKRILTTEFVHGTSIDKITIENHNQETRDWISKNILSLCLAELFEFNFMQVDPNWTNFVVDFENKRINLLDFGACRNYKSEFLFNYLKSIEGGVNRDINQILEYSLKLGYLTGDENKQMNDAQAKSILILSEPFSKLYYKENNLKTYPFNEKQIAKRISQLIPTMLKNRLKPPPEETYSLHRKLSGCYLVCSKLKSNINSTLIFNHFKNIFYKNYK", "length": 565 }, "evidence": [ { "id": "A0A5G2R212", "url": "https://omabrowser.org/oma/group/A0A5G2R212/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5BJQ0-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "Coq8a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAMLGDAIMVAKGLAKLTQAAVETHLQNLGLGGELILAARALQSTAVEQISMVFGKVQGQDKHEDSYATENFEDLEAEVQFSTPQAAGSSPDFSTASSLDQPLSSSLGHAHREGPAPAYVSSGPFREAGLSGQATSPLGRVNGRLFVDCRDLFLANSIQRRFFHQDQAPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSENSTGKKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNNDLGPHWRDKLEYFEERPFAAASIGQVHLARLKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELITGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLIPPPEETYSLHRKMGGSFLICSKLKACFPCKAMFEEAYSNYCRMKSGLQ", "length": 649 }, "evidence": [ { "id": "A0A5G2R212", "url": "https://omabrowser.org/oma/group/A0A5G2R212/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60936-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "Coq8a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAMLGDAIMVAKGLAKLTQAAVETHLQNLGLGGELLLAARALQSTAVEQFSMVFGKVQGQDKHEDSYATENFEDLEAEVQFSTPQAAGTSLDFSAASSLDQSLSPSHSQGPAPAYASSGPFREAGLPGQATSPMGRVNGRLFVDHRDLFLANGIQRRSFHQDQSSVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGIGALAEVAKKSLRSENSTGKKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNSDLGPHWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELISGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPVMLKHRLIPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCRMKSGLQ", "length": 645 }, "evidence": [ { "id": "A0A5G2R212", "url": "https://omabrowser.org/oma/group/A0A5G2R212/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NI60-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "COQ8A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQGQDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYVASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEKARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSEDPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRDLLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAKSIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ", "length": 647 }, "evidence": [ { "id": "A0A5G2R212", "url": "https://omabrowser.org/oma/group/A0A5G2R212/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SBB2-1", "protein_name": "Protein ABC transporter 1, mitochondrial", "gene_name": "ABC1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSWSKSFTRLVNGVSLVAKEIYNQSPELQRARNGDLEGLITSSGKKALVAATDLVGLTSGKLRELSIRRSKEPSVVYFDEGDNKDNVVATPEVRSVNTKPSEKIVDSKVLRNEFSDEVKNSNREGEIKVSGVEAGEIIGVRAVESGTVTEASSPSEVVPPVKRRRPRERKVPSTPMARAYGFFNLGAALAWGAVKESTYRMVNGTPMTPDNQPALSSLMSKENAERLALGLCEMRGAALKVGQMLSIQDESLVPAPILNALEYVRQGADVMPRSQLNPVLDAELGSNWQSKLTSFDYEPLAAASIGQVHRAVTKDGLEVAMKIQYPGVANSIESDIENVRRLLNYTNLIPKGLFLDRAIKVAKEELAQECDYEIEAVSQKRFRDLLSDTPGFYVPLVVDETSSKKILTTELISGIPIDKVALLDQKTRDYVGRKMLELTLKELFVFRFMQTDPNWGNFLYNEATKTINLIDFGAARDYPKKFVDDYLRMVMACAEKDSEGVIEMSRRLGFLTGDESDVMLDAHVQAGFIVGLPFAEPGGYAFRTNNIASSISNLGATMLKHRLSPPPDEAYSLHRKLSGAFLACIKLGATVPCRDLLLQVYNKYQFDDEPQDPVVATSSVSS", "length": 623 }, "evidence": [ { "id": "A0A5G2R212", "url": "https://omabrowser.org/oma/group/A0A5G2R212/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VYI6-1", "protein_name": "Coenzyme Q8", "gene_name": "Coq8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRSAQEAAALLRGLRILLEACGREHLAHGRHLWSNSSIRELIAENVAHTQQLVRSSSQNPTEELKKLQQTVKETGERGYVVAKGICSLLETKIKMSREESAISEPAQVSSIRKSTPTAQNPASWDAANLDISSITLQEFEEILSRRNKDRSVSLRTPATKSNQTMPKKETSTNPGIITQDTEYVNNVLRFVAGAKVEEQPPDAQPKKKSDQPAIEVPELSKVAKQRKVPSSRIGRMASFGGLFAGLGLGTLNELTKGALGLGGSTSMREALLSPANAERIVDTLCKVRGAALKIGQILSIQDSSVVSPQLAKAFERVRQAADYMPDWQVERVMNTQLGADWRQRLKSFEDKPFAAASIGQVHRATLSDGMDVAIKIQYPGVAQSIESDIDNLVGMLKVWDVFPQGFFIDNVVRVAKRELQWEVDYDREAEYTEKFREMIAPYPEYYVPRVVRDLTTSSVLTTELVPGVPLDKCFDLSYEHRRHIAASVLKLCLRELFEIECMQTDPNWSNFLYDAPSRRLMLIDFGSTRFYRHEFIRNYRRVIMSAAENNRQGVLEMSREMGFLTGYETKQMEQAHVDAVMILGEIFRYDGDFDFGRQNTTERLAALVPTMVAHRLCPPPEEIYSIHRKLSGIFLLCARLNVRMNCVPFYKDIVLGKFKD", "length": 661 }, "evidence": [ { "id": "A0A5G2R212", "url": "https://omabrowser.org/oma/group/A0A5G2R212/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R212", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R212", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R212", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212" } ], "pmid": "" }, { "name": "ADP binding", "id": "GO:0043531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043531", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R212", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R212", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212" } ], "pmid": "" }, { "name": "extrinsic component of mitochondrial inner membrane", "id": "GO:0031314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031314", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R212", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R212", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R212-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 677, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R212-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R212" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R212", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R212" }, { "id": "PF03109", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03109" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC1 atypical kinase-like", "eco_id": "ECO_0000259", "start_pos": 341, "end_pos": 568, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 409, "end_pos": 411 }, { "start_pos": 519, "end_pos": 521 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZK0-1", "uniprot_ac": "A0A5G2QZK0", "uniprot_id": "A0A5G2QZK0_PIG", "mass": { "chemical_mass": 21504.0, "monoisotopic_mass": 21504.0 }, "refseq": { "ac": "XP_003124984", "name": "39S ribosomal protein L35, mitochondrial isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124984" }, "gene_names": [ { "name": "MRPL35", "type": "recommended", "evidence": [ { "id": "A0A5G2QZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0" } ] }, { "name": "MRPL35", "type": "synonym", "evidence": [ { "id": "XP_003124984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124984" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein bL35m", "type": "recommended", "evidence": [ { "id": "A0A5G2QZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L35, mitochondrial isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003124984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124984" } ] }, { "name": "39S ribosomal protein L35, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A5G2QZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZK0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MRPL35", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0", "locus": { "chromosome": "3", "start_pos": 58560680, "end_pos": 58575081, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021746", "url": "https://www.ensembl.org/id/ENSSSCG00000021746" } ] } } ], "crossref": [ { "id": "A0A5G2QZK0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000021746", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000021746", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100517705", "url": "https://www.ncbi.nlm.nih.gov/gene/100517705", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "4CE4", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=4CE4&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "4V19", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=4V19&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "5AJ4", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5AJ4&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6GAW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6GAW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6GB2", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6GB2&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6YDP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6YDP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6YDW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6YDW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NQH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NQH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NQL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NQL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NSH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NSH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NSI", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NSI&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NSJ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NSJ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8OIN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OIN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8OIQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OIQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR019338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037229", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037229", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517705", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517705", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TYCSTRK", "url": "https://omabrowser.org/oma/group/TYCSTRK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QZK0", "url": "https://www.orthodb.org/?gene=A0A5G2QZK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15909:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15909:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00004ce4", "url": "https://www.rcsb.org/structure/pdb_00004ce4", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00004v19", "url": "https://www.rcsb.org/structure/pdb_00004v19", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00005aj4", "url": "https://www.rcsb.org/structure/pdb_00005aj4", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006gaw", "url": "https://www.rcsb.org/structure/pdb_00006gaw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006gb2", "url": "https://www.rcsb.org/structure/pdb_00006gb2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006ydp", "url": "https://www.rcsb.org/structure/pdb_00006ydp", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006ydw", "url": "https://www.rcsb.org/structure/pdb_00006ydw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nqh", "url": "https://www.rcsb.org/structure/pdb_00007nqh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nql", "url": "https://www.rcsb.org/structure/pdb_00007nql", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nsh", "url": "https://www.rcsb.org/structure/pdb_00007nsh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nsi", "url": "https://www.rcsb.org/structure/pdb_00007nsi", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nsj", "url": "https://www.rcsb.org/structure/pdb_00007nsj", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008oin", "url": "https://www.rcsb.org/structure/pdb_00008oin", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008oiq", "url": "https://www.rcsb.org/structure/pdb_00008oiq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4CE4", "url": "https://www.rcsb.org/structure/4CE4", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4V19", "url": "https://www.rcsb.org/structure/4V19", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5AJ4", "url": "https://www.rcsb.org/structure/5AJ4", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6GAW", "url": "https://www.rcsb.org/structure/6GAW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6GB2", "url": "https://www.rcsb.org/structure/6GB2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6YDP", "url": "https://www.rcsb.org/structure/6YDP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6YDW", "url": "https://www.rcsb.org/structure/6YDW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NQH", "url": "https://www.rcsb.org/structure/7NQH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NQL", "url": "https://www.rcsb.org/structure/7NQL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NSH", "url": "https://www.rcsb.org/structure/7NSH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NSI", "url": "https://www.rcsb.org/structure/7NSI", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NSJ", "url": "https://www.rcsb.org/structure/7NSJ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OIN", "url": "https://www.rcsb.org/structure/8OIN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OIQ", "url": "https://www.rcsb.org/structure/8OIQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF01632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003124984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124984", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZLJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZK0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SVC5", "url": "https://www.uniprot.org/uniprotkb/F1SVC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SVC5-1", "url": "https://www.uniprot.org/uniprotkb/F1SVC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASAFAGAVRAATGILRPLHILASSAYQNCAKNACLSSVLSSRHFSHIQTSALLSAPRLITSVRNLMCGPTAPVLNRVAPLLPHVLKPPVRTVTYFSSRKGKRKTVKAVIYRFLRLHSGLWLRRKAGYKKKLWKKTAARKRRLREFVFCNKTQSKLLDKMTTSFWKRRNWYADDPYQKYQDRTNLKV", "length": 188, "header": "tr|A0A5G2QZK0-1|A0A5G2QZK0_PIG Isoform 1 of Large ribosomal subunit protein bL35m OS=Sus scrofa OX=9823 GN=MRPL35 PE=1 SV=2 CANONICAL=A0A5G2QZK0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZLJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0/entry#A0A286ZLJ1-1", "sequence": { "sequence": "FVASAYACVCFSPSPGILRPLHILASSAYQNCAKNACLSSVLSSRHFSHIQTSALLSAPRLITSVRNLMCGPTAPVLNRVAPLLPHVLKPPVRTVTYFSSRKGKRKTVKAVIYRFLRLHSGLWLRRKAGYKKKLWKKTAARKRRLREFVFCNKTQSKLLDKMTTSFWKRRNWYADDPYQKYQDRTNLKV", "length": 189, "header": "tr|A0A286ZLJ1-1|A0A5G2QZK0_PIG Computationally mapped isoform of Large ribosomal subunit protein bL35m OS=Sus scrofa OX=9823 GN=MRPL35 PE=1 SV=2 CANONICAL=A0A5G2QZK0-1" }, "locus": { "chromosome": "3", "start_pos": 58567204, "end_pos": 58562692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038986.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038986.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032438.2", "url": "https://www.ensembl.org/id/ENSSSCP00000032438.2" } ] } }, { "isoform_ac": "A0A5G2QZK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0/entry#A0A5G2QZK0-1", "sequence": { "sequence": "MAASAFAGAVRAATGILRPLHILASSAYQNCAKNACLSSVLSSRHFSHIQTSALLSAPRLITSVRNLMCGPTAPVLNRVAPLLPHVLKPPVRTVTYFSSRKGKRKTVKAVIYRFLRLHSGLWLRRKAGYKKKLWKKTAARKRRLREFVFCNKTQSKLLDKMTTSFWKRRNWYADDPYQKYQDRTNLKV", "length": 188, "header": "tr|A0A5G2QZK0-1|A0A5G2QZK0_PIG Isoform 1 of Large ribosomal subunit protein bL35m OS=Sus scrofa OX=9823 GN=MRPL35 PE=1 SV=2 CANONICAL=A0A5G2QZK0-1" }, "locus": { "chromosome": "3", "start_pos": 58571244, "end_pos": 58562692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088999.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088999.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070311.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070311.2" } ] } }, { "isoform_ac": "F1SVC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0/entry#F1SVC5-1", "sequence": { "sequence": "MAASAFAGAVRAATGILRPLHILASSAYQNCAKNACLSSVLSSRHFSHIQTSALLSAPRLITSVRNLMCGPTAPVLNRLVIRKNYGRRRLHEKDA", "length": 95, "header": "tr|F1SVC5-1|F1SVC5_PIG Computationally mapped isoform of Mitochondrial ribosomal protein L35 OS=Sus scrofa OX=9823 GN=MRPL35 PE=1 SV=2 CANONICAL=A0A5G2QZK0-1" }, "locus": { "chromosome": "3", "start_pos": 58571244, "end_pos": 58562826, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030403.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030403.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023814.2", "url": "https://www.ensembl.org/id/ENSSSCP00000023814.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 72, "start_aa": "Thr", "end_pos": 72, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr72", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Architecture of the large subunit of the mammalian mitochondrial ribosome.", "journal": "Nature", "date": "2014", "authors": "Greber Basil J, Boehringer Daniel, Leitner Alexander, Bieri Philipp, Voigts-Hoffmann Felix, Erzberger Jan P, Leibundgut Marc, Aebersold Ruedi, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "F1SVC5", "url": "https://www.uniprot.org/uniprotkb/F1SVC5" } ], "reference": [ { "type": "PubMed", "id": "24362565", "url": "https://glygen.org/publication/PubMed/24362565" } ] }, { "title": "The complete structure of the large subunit of the mammalian mitochondrial ribosome.", "journal": "Nature", "date": "2014", "authors": "Greber Basil J, Boehringer Daniel, Leibundgut Marc, Bieri Philipp, Leitner Alexander, Schmitz Nikolaus, Aebersold Ruedi, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "F1SVC5", "url": "https://www.uniprot.org/uniprotkb/F1SVC5" } ], "reference": [ { "type": "PubMed", "id": "25271403", "url": "https://glygen.org/publication/PubMed/25271403" } ] }, { "title": "Ribosome. The complete structure of the 55S mammalian mitochondrial ribosome.", "journal": "Science", "date": "2015", "authors": "Greber BJ, Bieri P, Leibundgut M, Leitner A, Aebersold R, Boehringer D, Ban N", "evidence": [ { "database": "UniProtKB", "id": "F1SVC5", "url": "https://www.uniprot.org/uniprotkb/F1SVC5" } ], "reference": [ { "type": "PubMed", "id": "25837512", "url": "https://glygen.org/publication/PubMed/25837512" } ] }, { "title": "Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.", "journal": "Nature", "date": "2018", "authors": "Kummer Eva, Leibundgut Marc, Rackham Oliver, Lee Richard G, Boehringer Daniel, Filipovska Aleksandra, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "F1SVC5", "url": "https://www.uniprot.org/uniprotkb/F1SVC5" } ], "reference": [ { "type": "PubMed", "id": "30089917", "url": "https://glygen.org/publication/PubMed/30089917" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SVC5", "url": "https://www.uniprot.org/uniprotkb/F1SVC5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Structural insights into mammalian mitochondrial translation elongation catalyzed by mtEFG1.", "journal": "EMBO J.", "date": "2020", "authors": "Kummer E, Ban N", "evidence": [ { "database": "UniProtKB", "id": "F1SVC5", "url": "https://www.uniprot.org/uniprotkb/F1SVC5" } ], "reference": [ { "type": "PubMed", "id": "32602580", "url": "https://glygen.org/publication/PubMed/32602580" } ] }, { "title": "Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.", "journal": "Mol. Cell", "date": "2021", "authors": "Kummer Eva, Schubert Katharina Noel, Schoenhut Tanja, Scaiola Alain, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "F1SVC5", "url": "https://www.uniprot.org/uniprotkb/F1SVC5" } ], "reference": [ { "type": "PubMed", "id": "33878294", "url": "https://glygen.org/publication/PubMed/33878294" } ] }, { "title": "Molecular basis of translation termination at noncanonical stop codons in human mitochondria.", "journal": "Science", "date": "2023", "authors": "Saurer Martin, Leibundgut Marc, Nadimpalli Hima Priyanka, Scaiola Alain, Sch\u00f6nhut Tanja, Lee Richard G, Siira Stefan J, Rackham Oliver, Dreos Ren\u00e9, Lenar\u010di\u010d Tea, Kummer Eva, Gatfield David, Filipovska Aleksandra, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZK0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0" } ], "reference": [ { "type": "PubMed", "id": "37141370", "url": "https://glygen.org/publication/PubMed/37141370" } ] } ], "pathway": [ { "id": "ssc:100517705", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517705", "resource": "KEGG Pathway" }, { "id": "R-SSC-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-SSC-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-SSC-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MF78-1", "protein_name": "Large ribosomal subunit protein bL35m", "gene_name": "Mrpl35", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAASVFTGALRAASGILRPLNVLASSTYRNYAKNACLTSALCTIHFRHIQTPVVSFAPRLVTSVRNLTHGHTATVLNRVAALVPSVLKPPVRTLTYCSTRKGKRKTVKSVVHRFLRLHSGLWLRRKAGYKKKLWKKSTARKKRLREFVFCNKTQSKLLDKMTTSFWKRRNWYADDPYLMYHDRTNLRV", "length": 188 }, "evidence": [ { "id": "A0A5G2QZK0", "url": "https://omabrowser.org/oma/group/A0A5G2QZK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I5ZYT3-1", "protein_name": "Large ribosomal subunit protein bL35m", "gene_name": "Mrpl35", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HSSRHQEALHQQRILRPLNVSVSSTYRNCARNACLSSALRTIPFRHIQTSVVSSAPRLVKSVGHLAYGHTASVLNRVATLVPSVLKPPVRALTYCSARKGKRKTVKSVVHRFLRLHSGLWLRRKAGYKKKLWKKSTARKKRLREFVFCNKTQSKLLDKMTTSFWKRRNWYTGDPYQMYHDRTNLRV", "length": 186 }, "evidence": [ { "id": "A0A5G2QZK0", "url": "https://omabrowser.org/oma/group/A0A5G2QZK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3SZA9-1", "protein_name": "Large ribosomal subunit protein bL35m", "gene_name": "MRPL35", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAASMFAGAVRAASGILRPLNILASSAYRNCTKNACLNSILSSRHFSHIQTPVVSSAPRLITSVRNLTCGQTATVLNRMALLLPNVLKPPVRTVTYCSSRKGKRKTVKAVIYRFLRLHSGLWLRRKAGYKKKLWKKTVARKRRLREFVFCNKTQSKLLDKMTTSFWKRRNWYADDPYQMYHDRTNLKV", "length": 188 }, "evidence": [ { "id": "A0A5G2QZK0", "url": "https://omabrowser.org/oma/group/A0A5G2QZK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CQL6-1", "protein_name": "Large ribosomal subunit protein bL35m", "gene_name": "Mrpl35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASIFTGAVRAASGIFRPLNVLASSTYRNCARNACLNSSLCTIHFRHIQTSVVSSAPRLVTSVGHLAYGHTTTVLNRVATLVPSVLKPPVRALTYCSTRKGKRKTVKSVVHRFLRLHSGLWLRRKAGYKKKLWKKSTARKKRLREFVFCSKTQSKLLDKMTTSFWKRRNWYAGDPYQMYHDRTNLRV", "length": 188 }, "evidence": [ { "id": "A0A5G2QZK0", "url": "https://omabrowser.org/oma/group/A0A5G2QZK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZE8-1", "protein_name": "Large ribosomal subunit protein bL35m", "gene_name": "MRPL35", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASAFAGAVRAASGILRPLNILASSTYRNCVKNASLISALSTGRFSHIQTPVVSSTPRLTTSERNLTCGHTSVILNRMAPVLPSVLKLPVRSLTYFSARKGKRKTVKAVIDRFLRLHCGLWVRRKAGYKKKLWKKTPARKKRLREFVFCNKTQSKLLDKMTTSFWKRRNWYVDDPYQKYHDRTNLKV", "length": 188 }, "evidence": [ { "id": "A0A5G2QZK0", "url": "https://omabrowser.org/oma/group/A0A5G2QZK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZK0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZK0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZK0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZK0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZK0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZK0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZK0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 188, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZK0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZK0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 72 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0F8-1", "uniprot_ac": "A0A5G2R0F8", "uniprot_id": "A0A5G2R0F8_PIG", "mass": { "chemical_mass": 80905.0, "monoisotopic_mass": 80905.0 }, "refseq": { "ac": "XP_013845413", "name": "mitochondrial Rho GTPase 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845413" }, "gene_names": [ { "name": "RHOT1", "type": "recommended", "evidence": [ { "id": "A0A5G2R0F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ] }, { "name": "RHOT1", "type": "synonym", "evidence": [ { "id": "XP_013845413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845413" } ] } ], "protein_names": [ { "name": "Mitochondrial Rho GTPase", "type": "recommended", "evidence": [ { "id": "A0A5G2R0F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.-", "type": "synonym", "evidence": [ { "id": "A0A5G2R0F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial Rho GTPase 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_013845413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845413" } ] } ], "function": [ { "annotation": "Atypical mitochondrial nucleoside-triphosphatase (NTPase) involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Can hydrolyze GTP, ATP and UTP.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZRP2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRP2#function" }, { "database": "UniProtKB", "id": "PIRNR037488", "url": "https://www.uniprot.org/uniprotkb/PIRNR037488#function" }, { "database": "UniProtKB", "id": "ARBA00093289", "url": "https://www.uniprot.org/uniprotkb/ARBA00093289#function" }, { "database": "UniProtKB", "id": "A0A286ZWW1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWW1#function" }, { "database": "UniProtKB", "id": "A0A287A323", "url": "https://www.uniprot.org/uniprotkb/A0A287A323#function" }, { "database": "UniProtKB", "id": "A0A8W4FKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKW7#function" }, { "database": "UniProtKB", "id": "A0A287A1F4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1F4#function" }, { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8#function" }, { "database": "UniProtKB", "id": "F1RKW4", "url": "https://www.uniprot.org/uniprotkb/F1RKW4#function" }, { "database": "UniProtKB", "id": "A0A5G2QWH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWH3#function" }, { "database": "UniProtKB", "id": "A0A5G2R4R0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R0#function" }, { "database": "UniProtKB", "id": "A0A5G2RCK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RHOT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8", "locus": { "chromosome": "12", "start_pos": 42711233, "end_pos": 42783421, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017735", "url": "https://www.ensembl.org/id/ENSSSCG00000017735" } ] } } ], "crossref": [ { "id": "A0A5G2R0F8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0F8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017735", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017735", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01892", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01892", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01893", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01893", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523466", "url": "https://www.ncbi.nlm.nih.gov/gene/100523466", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523466", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523466", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HETTWGI", "url": "https://omabrowser.org/oma/group/HETTWGI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287A1F4", "url": "https://www.orthodb.org/?gene=A0A287A1F4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46819", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46819", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46819:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46819:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08355", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08355", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08356", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08356", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013425", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013425", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013845413", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845413", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64900", "url": "https://www.rhea-db.org/rhea/64900", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZRP2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZRP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZWW1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZWW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1F4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1F4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A323", "url": "https://www.uniprot.org/uniprotkb/A0A287A323", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A323-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A323-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4R0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RKW4", "url": "https://www.uniprot.org/uniprotkb/F1RKW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RKW4-1", "url": "https://www.uniprot.org/uniprotkb/F1RKW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAGRARPLRAADMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGMKNCGKTGVLQALLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEILCDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPADFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRDRLSRDTGNTDRIENLRKVWVFLKTAFHARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFSAVLNRHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR", "length": 704, "header": "tr|A0A5G2R0F8-1|A0A5G2R0F8_PIG Isoform 1 of Mitochondrial Rho GTPase OS=Sus scrofa OX=9823 GN=RHOT1 PE=1 SV=1 CANONICAL=A0A5G2R0F8-1" }, "isoforms": [ { "isoform_ac": "A0A286ZRP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8/entry#A0A286ZRP2-1", "sequence": { "sequence": "MRAGRARPLRAADMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGMKNCGKTGVLQALLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEILCDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPADFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRDRLSRDTGNTDRIENLRKVWVFLKTALHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR", "length": 663, "header": "tr|A0A286ZRP2-1|A0A5G2R0F8_PIG Computationally mapped isoform of Mitochondrial Rho GTPase OS=Sus scrofa OX=9823 GN=RHOT1 PE=1 SV=1 CANONICAL=A0A5G2R0F8-1" }, "locus": { "chromosome": "12", "start_pos": 42783237, "end_pos": 42712216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045634.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045634.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034247.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034247.1" } ] } }, { "isoform_ac": "A0A286ZWW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8/entry#A0A286ZWW1-1", "sequence": { "sequence": "MRAGRARPLRAADMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGMKNCGKTGVLQALLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEILCDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPADFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFSAVLNRLRARVAEWGATLLADDEGSITHQVHAVHSVEDSIFMESSHGPLFLEARHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR", "length": 720, "header": "tr|A0A286ZWW1-1|A0A5G2R0F8_PIG Computationally mapped isoform of Mitochondrial Rho GTPase OS=Sus scrofa OX=9823 GN=RHOT1 PE=1 SV=1 CANONICAL=A0A5G2R0F8-1" }, "locus": { "chromosome": "12", "start_pos": 42783237, "end_pos": 42712216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056201.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056201.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035944.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035944.1" } ] } }, { "isoform_ac": "A0A287A1F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8/entry#A0A287A1F4-1", "sequence": { "sequence": "MRAGRARPLRAADMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGMKNCGKTGVLQALLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEILCDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPADFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRDRLSRDTGNTDRIENLRKVWVFLKTAFHARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFSAVLNRLRARVAEWGATLLADDEGSITHQVHAVHSVEDSIFMESSHGPLFLEARHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR", "length": 752, "header": "tr|A0A287A1F4-1|A0A5G2R0F8_PIG Computationally mapped isoform of Mitochondrial Rho GTPase OS=Sus scrofa OX=9823 GN=RHOT1 PE=1 SV=2 CANONICAL=A0A5G2R0F8-1" }, "locus": { "chromosome": "12", "start_pos": 42783237, "end_pos": 42712216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036939.3", "url": "https://www.ensembl.org/id/ENSSSCT00000036939.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037756.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037756.2" } ] } }, { "isoform_ac": "A0A287A323-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8/entry#A0A287A323-1", "sequence": { "sequence": "MRAGRARPLRAADMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGMKNCGKTGVLQALLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEILCDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPADFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR", "length": 631, "header": "tr|A0A287A323-1|A0A5G2R0F8_PIG Computationally mapped isoform of Mitochondrial Rho GTPase OS=Sus scrofa OX=9823 GN=RHOT1 PE=1 SV=1 CANONICAL=A0A5G2R0F8-1" }, "locus": { "chromosome": "12", "start_pos": 42783237, "end_pos": 42712216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052850.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052850.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038352.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038352.1" } ] } }, { "isoform_ac": "A0A5G2QWH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8/entry#A0A5G2QWH3-1", "sequence": { "sequence": "MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGMKNCGKTGVLQALLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEILCDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPADFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP", "length": 580, "header": "tr|A0A5G2QWH3-1|A0A5G2QWH3_PIG Computationally mapped isoform of Ras homolog gene family member T1 OS=Sus scrofa OX=9823 GN=RHOT1 PE=1 SV=1 CANONICAL=A0A5G2R0F8-1" }, "locus": { "chromosome": "12", "start_pos": 42783198, "end_pos": 42729570, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082888.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082888.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069211.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069211.1" } ] } }, { "isoform_ac": "A0A5G2R0F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8/entry#A0A5G2R0F8-1", "sequence": { "sequence": "MRAGRARPLRAADMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGMKNCGKTGVLQALLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEILCDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPADFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRDRLSRDTGNTDRIENLRKVWVFLKTAFHARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFSAVLNRHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR", "length": 704, "header": "tr|A0A5G2R0F8-1|A0A5G2R0F8_PIG Isoform 1 of Mitochondrial Rho GTPase OS=Sus scrofa OX=9823 GN=RHOT1 PE=1 SV=1 CANONICAL=A0A5G2R0F8-1" }, "locus": { "chromosome": "12", "start_pos": 42783237, "end_pos": 42712216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087981.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087981.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063995.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063995.1" } ] } }, { "isoform_ac": "A0A5G2R4R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8/entry#A0A5G2R4R0-1", "sequence": { "sequence": "LKNLIREFFLFYICLQTKVPPRAEEITIPADVTPERVPTHIVDYSGSAYLLWANVICIVYAVNNKLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTVTARLKLWYVTFIILQVLTRDKKIDLQKKQTQRNVFRCNVIGMKNCGKTGVLQALLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEILCDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPADFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRDRLSRDTGNTDRIENLRKVWVFLKTAL", "length": 551, "header": "tr|A0A5G2R4R0-1|A0A5G2R0F8_PIG Computationally mapped isoform of Mitochondrial Rho GTPase OS=Sus scrofa OX=9823 GN=RHOT1 PE=1 SV=1 CANONICAL=A0A5G2R0F8-1" }, "locus": { "chromosome": "12", "start_pos": 42762140, "end_pos": 42728420, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085989.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085989.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071323.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071323.1" } ] } }, { "isoform_ac": "A0A5G2RCK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8/entry#A0A5G2RCK8-1", "sequence": { "sequence": "MRAGRARPLRAADMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSGSAYLLWANVICIVYAVNNKLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTVTARLKLWYVTFIILQVLTRDKKIDLQKKQTQRNVFRCNVIGMKNCGKTGVLQALLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEILCDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPADFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRDRLSRDTGNTDRIENLRKVWVFLKTAFHARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFSAVLNRLRARVAEWGATLLADDEGSITHQVHAVHSVEDSIFMESSHGPLFLEARHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR", "length": 705, "header": "tr|A0A5G2RCK8-1|A0A5G2RCK8_PIG Computationally mapped isoform of Ras homolog gene family member T1 OS=Sus scrofa OX=9823 GN=RHOT1 PE=1 SV=2 CANONICAL=A0A5G2R0F8-1" }, "locus": { "chromosome": "12", "start_pos": 42783237, "end_pos": 42712216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081459.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081459.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068384.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068384.2" } ] } }, { "isoform_ac": "A0A8W4FKW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8/entry#A0A8W4FKW7-1", "sequence": { "sequence": "RRKDLSIMLRLARVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSGSAYLLWANVICIVYAVNNKLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTVTARLKLWYVTFIILQVLTRDKKIDLQKKQTQRNVFRCNVIGMKNCGKTGVLQALLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEILCDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPADFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP", "length": 532, "header": "tr|A0A8W4FKW7-1|A0A5G2R0F8_PIG Computationally mapped isoform of Mitochondrial Rho GTPase OS=Sus scrofa OX=9823 GN=RHOT1 PE=1 SV=1 CANONICAL=A0A5G2R0F8-1" }, "locus": { "chromosome": "12", "start_pos": 42763082, "end_pos": 42729570, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094656.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094656.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079847.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079847.1" } ] } }, { "isoform_ac": "F1RKW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8/entry#F1RKW4-1", "sequence": { "sequence": "MRAGRARPLRAADMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGMKNCGKTGVLQALLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEILCDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPADFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPCTPSTL", "length": 599, "header": "tr|F1RKW4-1|A0A5G2R0F8_PIG Computationally mapped isoform of Mitochondrial Rho GTPase OS=Sus scrofa OX=9823 GN=RHOT1 PE=1 SV=3 CANONICAL=A0A5G2R0F8-1" }, "locus": { "chromosome": "12", "start_pos": 42783237, "end_pos": 42713848, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019302.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019302.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018790.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018790.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4R0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523466", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523466", "resource": "KEGG Pathway" }, { "id": "R-SSC-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-SSC-9013425", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013425", "resource": "Reactome", "description": "RHOT1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1ADZ7-1", "protein_name": "Mitochondrial Rho GTPase", "gene_name": "RHOT1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQNDEQLYHEISQANVICIVYAVNNKNSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFRISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKNVSDGVADNGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLELTPEYLFPLLKIPPDCTTELNHHAYLFLQSIFDKHDLDRDCALSPDELKDLFKVFPYMPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILAEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVVGMKGCGKSGVLQALLGRNLMRQRQIRAEHKSYYAINTVYVYGQEKYLLLHDVSDSEFLTDAETICDVVCLVYDVSNPKSFEYCVRIFKQHFMDSRIPCLVVAAKSDLHEVRQEYSISPAEFCKKHKMPPPQAFTCNTVDMPSKDIFVKLTTMAMYPHARLRCMCACNRCTFCICQNFLNSDLLQSVKNKLFTAVLNRLRPHIDELGAMLLADEESSIMHQVHAVSFVEDSIFMESSLGPRLLEDRHVTQADLKSSTFWLRASFGATVFAFLGFAMYKALIKQR", "length": 707 }, "evidence": [ { "id": "A0A5G2R0F8", "url": "https://omabrowser.org/oma/group/A0A5G2R0F8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P39722-1", "protein_name": "Mitochondrial Rho GTPase 1", "gene_name": "GEM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTKETIRVVICGDEGVGKSSLIVSLTKAEFIPTIQDVLPPISIPRDFSSSPTYSPKNTVLIDTSDSDLIALDHELKSADVIWLVYCDHESYDHVSLFWLPHFRSLGLNIPVILCKNKCDSISNVNANAMVVSENSDDDIDTKVEDEEFIPILMEFKEIDTCIKTSAKTQFDLNQAFYLCQRAITHPISPLFDAMVGELKPLAVMALKRIFLLSDLNQDSYLDDNEILGLQKKCFNKSIDVNELNFIKDLLLDISKHDQEYINRKLYVPGKGITKDGFLVLNKIYAERGRHETTWAILRTFHYTDSLCINDKILHPRLVVPDTSSVELSPKGYRFLVDIFLKFDIDNDGGLNNQELHRLFKCTPGLPKLWTSTNFPFSTVVNNKGCITLQGWLAQWSMTTFLNYSTTTAYLVYFGFQEDARLALQVTKPRKMRRRSGKLYRSNINDRKVFNCFVIGKPCCGKSSLLEAFLGRSFSEEYSPTIKPRIAVNSLELKGGKQYYLILQELGEQEYAILENKDKLKECDVICLTYDSSDPESFSYLVSLLDKFTHLQDLPLVFVASKADLDKQQQRCQIQPDELADELFVNHPLHISSRWLSSLNELFIKITEAALDPGKNTPGLPEETAAKDVDYRQTALIFGSTVGFVALCSFTLMKLFKSSKFSK", "length": 662 }, "evidence": [ { "id": "A0A5G2R0F8", "url": "https://omabrowser.org/oma/group/A0A5G2R0F8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55G45-1", "protein_name": "Probable mitochondrial Rho GTPase gemA", "gene_name": "gemA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNNIKVILIGDEQVGKSTIINSFISESFSEITQKTLPEVTIPAEFNNEICSTRIIDTFDDGKNLKNQMNMEIRTADAIVIVYSVDRFDTFMSIRMKWIPLINQLRGSNKSPIIIVGNKLDLVDDKHENNKVQIEETIQYFRSTYSNTIQWLECSAKTMENLPELLYASQTSVFFPERILYNREENKMTEGCERALKRIFKLCDHDNDGSLSEEEINYFQTKCGHETMTSEEIQNIQQFVLSKIPDGVNSNGFTEKGFLYMNLLFLLRGPCQHTWTSLRSFNYDDDLVLLESYVHPTLQVPPNHNTILSSMGNEFFKSLFEKYDSDSDGVLSSFDLVSLFSTTPKIPWEIGFEKHFNTDKDSNLTLSGFLSLWNLQTYENYKVTLEYLAYFGSQTENNNIDMISILNSRELDIKSNQFTRNIVNCYVFGAEAVGKTTFLNTFIGKSFSTLYNATNGNDNFKVCGHLLKNKYLILSEYVGEKIPTAELKSKCDLVCLLYDCNSEQSFKFIENIYNQLKQQQLNIPIVFIRTKNNNNNNNNNNNNNNNNNNNNLNNNNNNINNNNNNNNNNTTTTNANVSTSKIIDSFFKSHKNYSPKDFSISRSNSIYHEMMETIVNSSFNDNSNGSNGSNNSNILTYLVIAAGVAGVGLLLSKYLAKK", "length": 658 }, "evidence": [ { "id": "A0A5G2R0F8", "url": "https://omabrowser.org/oma/group/A0A5G2R0F8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6NVC5-1", "protein_name": "Mitochondrial Rho GTPase 1-A", "gene_name": "rhot1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRKDVRILLVGEPKVGKTSLIMSLVSEEFPDEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLYQEITKANVICIVYSVNNKKSIEKVTSHWIPLINERTDKDSRVPLILVGNKSDLVEHSSMETILPIMNQYSEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYSPEEKEMKPSCIKALTRIFKISDLDNDGILNDNELNFFQRTCFNIPLAPQALEDVKNVVRKNMTDGVKDNGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLELTQEYLFPLFKIPPDCTTELNHNAYLFLQSVFDKHDKDRDCALSPDELKDLFKVFPYMPWGPDVNNTVCTNEQGWITYQGYLSQWTLTTYLDVQRCLEYLGYLGYSIIQEQESQAAAITVTRNKRIDLQKKQTQRSVFRCNVLGARGCGKSGFLQAFLGRNLVRQKRIREDHKSYYAISTTYVYGQEKYLLLHEVLPDVEFLSEADLACDVVCLVYDISNPRSFEYCAKVYKKHFMDSKTPCVIIAAKSDLHEARQYYSLSPLDFCRKHKLHPPQLFTCNTTEAPSKDLYTKLTTMAMYPHMTQADLKNSTFWLRASVGATVFAVLGFAMYKALLKQR", "length": 619 }, "evidence": [ { "id": "A0A5G2R0F8", "url": "https://omabrowser.org/oma/group/A0A5G2R0F8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BG51-1", "protein_name": "Mitochondrial Rho GTPase 1", "gene_name": "Rhot1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAGRVRPLRASDMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHLSDGVADSGLTLRGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFQVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGVKGCGKTGVLQSLLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAETICDVVCLVYDVTNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEHSISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASFGATVFAVVGFAMYRALLKQR", "length": 631 }, "evidence": [ { "id": "A0A5G2R0F8", "url": "https://omabrowser.org/oma/group/A0A5G2R0F8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IMX7-1", "protein_name": "Mitochondrial Rho GTPase", "gene_name": "Miro", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGQYTASQRKNVRILLVGDAGVGKTSLILSLVSEEYPEEVPPRAEEITIPANVTPEQVPTSIVDFSAVEQSEDALAAEINKAHVVCIVYAVDDDDTLDRITSHWLPLVRAKCNPSLDGEGDAEAEAEGDTQREPIRKPIVLVGNKIDLIEYSTMDSVLAIMEDYPEIESCVECSAKSLHNISEMFYYAQKAVLHPTSPLYMMEEQELTSACKKSLVRIFKICDIDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAVIQKNVPDGIYNDAVTLKGFLFLHCLFIQRGRNETTWAVLRRFGYNDQLEMCQEYLRPPLKIPPGSSTELSHRGQQFLIAVFERYDRDGDGALSPEEHKMLFSTCPAAPWSYSTDIRKSCPINETTGWVTLHGWLCRWTLMTLIDVVKTMEYLAYLGFNVHENDSQLAAIHVTRERRIDLAKRQSSRSVYKCHVIGPKGSGKTGMCRGFLVEDMHKLIGKEFKTNVVNCINSVQVYGQEKHLILRDIDVRHALDPLQPQEVNCDVACLVYDSSNPRSFEYVARIYIKYYAESKIPVMIVGTKCDMDERRQDYLMQPSEFCDKYKLLPPHLFSLKTNKKELYTKLATMAAFPHLRQFGLMTEDPKLWLKAGLGVAAATMLGFIVLKTISAAGAHTR", "length": 652 }, "evidence": [ { "id": "A0A5G2R0F8", "url": "https://omabrowser.org/oma/group/A0A5G2R0F8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8IXI2-1", "protein_name": "Mitochondrial Rho GTPase 1", "gene_name": "RHOT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFRCNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR", "length": 618 }, "evidence": [ { "id": "A0A5G2R0F8", "url": "https://omabrowser.org/oma/group/A0A5G2R0F8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" }, { "name": "establishment of mitochondrion localization, microtubule-mediated", "id": "GO:0034643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034643", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" }, { "name": "mitochondrion transport along microtubule", "id": "GO:0047497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047497", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" }, { "name": "cellular homeostasis", "id": "GO:0019725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019725", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" }, { "name": "regulation of mitochondrion organization", "id": "GO:0010821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010821", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" }, { "name": "mitochondrial outer membrane permeabilization", "id": "GO:0097345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097345", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "64900", "name": "", "equation": "UTP + H2O = UDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "64900", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64900" } ] }, { "id": "R-SSC-5696872", "name": "USP30 deubiquitinates Ub-MOM proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial outer membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5696872", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696872" } ] }, { "id": "R-SSC-9018814", "name": "RHOT1 hydrolyzes GTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial outer membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9018814", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018814" } ] }, { "id": "R-SSC-9018815", "name": "RHOT1 binds effectors at the mitochondrial outer membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial outer membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9018815", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018815" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0F8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 704, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0F8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0F8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 317, "end_pos": 352, "start_aa": "His", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R0F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0F8" }, { "id": "PS51423", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51423" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Miro", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 181, "start_aa": "Lys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 359, "end_pos": 361 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWP9-1", "uniprot_ac": "A0A5G2QWP9", "uniprot_id": "A0A5G2QWP9_PIG", "mass": { "chemical_mass": 192319.0, "monoisotopic_mass": 192319.0 }, "refseq": {}, "gene_names": [ { "name": "KIF1A", "type": "recommended", "evidence": [ { "id": "A0A5G2QWP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ] } ], "protein_names": [ { "name": "plus-end-directed kinesin ATPase", "type": "recommended", "evidence": [ { "id": "A0A5G2QWP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9/entry#names_and_taxonomy" } ] }, { "name": "5.6.1.3", "type": "synonym", "evidence": [ { "id": "A0A5G2QWP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KIF1A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9", "locus": { "chromosome": "15", "start_pos": 139610627, "end_pos": 139694826, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016401", "url": "https://www.ensembl.org/id/ENSSSCG00000016401" } ] } } ], "crossref": [ { "id": "A0A5G2QWP9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016401", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016401", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01233", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01233", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01365", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01365", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22726", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22726", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47117:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47117:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16183", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16183", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983189", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983189", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZS37", "url": "https://www.uniprot.org/uniprotkb/A0A286ZS37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZS37-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZS37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RE74", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RE74-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SHW6", "url": "https://www.uniprot.org/uniprotkb/F1SHW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SHW6-1", "url": "https://www.uniprot.org/uniprotkb/F1SHW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETSVTTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDTNTVPGGPKLTNALVGMSPSSSLSALSSRAASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGREDAEKRQDIVLSGHFIKEEHCVFRSDSRGGGEAVVTLEPCEGADTYVNGKKVTEPSVLRSGNRIIMGKSHVFRFNHPEQARQERERTPCAETPSEPVDWAFAQRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLDYESKLEALQKQMDSRYYPEVNEEEEEPEDEVQWTERECELALWAFRKWRWYQFTSLRDLLWGNAIFLKEANAISVELKKKVQFQFVLLTDTLYSPLPPDLLPPEAADRETRPFPRTIVAVEVQDQKNGATHYWTLEKLRQRLDLMREMYDRAAEVPSSVIEDCDNVVTGGDPFYDRFPWFRLVGRAFVYLSNLLYPVPLVHRVAIVSEKGEVKGFLRVAVQAISADEEAPDYGSGVRQSGTAKISFDDQHFEKFQSESCPGAGMSRSGASQEELRIVEGQGQGADAGPSADEVNNNTCSAVTPEGLLDSPEKATLDGPLDAALDHLGLGSTFTFRVTVLQASSISAEYADIFCQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAVEVTRSFIEYIKSQPIVFEVFGHYQQHPFPPLCKDVLSPLRPSRRHFPRVMPLSKPVPATKLSALTRHCPGPCHCKYDLLVYFEICELEANGDYIPAVVDHRGGMPCMGTFLLHQGIQRRITVTLLHETGSHIHWKEVRELVVGRIRNTPETDESLIDPNILSLNILSSGYIYPAQDDRQFLDSDMPRTFYQFEAAWDSSMHNSLLLNRVTPYREKIYMTLSAYIEMENCTQPAVITKDFCMVFYSRDAKLPASRSIRNLFGSGSLRASESNRVTGVYELSLCHVADAGSPGTQRRRRRVLDTSVAYVRGEENLAGWRPRSDSLILDHQWELEKLSLLQEVEKTRHYLLLREKLETAQRPGPEALSPASSEDSEAHSSSSASSPLAAEGRPSSLEAPNERQRELAVKCLRLLTHSFNREYTHSHVCISASESKLSEMSVTLLRDPSMSPLGAATLTPSSTCPSLVEGRYGAPDLRTPQPCSRPASPEPEPLPEADSKKLPSPARGASEADKETPRLLVPDIQEIRVSPIVSKKGYLHFLEPHTAGWAKRFVVVRRPYAYMYNSDKDAVERFVLNLSTAQVEYSEDQQAMLKTPNTFAVCTEHRGILLQANSDKDMHDWLYAFNPLLAGTIRSKLSRRRSAQMRV", "length": 1707, "header": "tr|A0A5G2QWP9-1|A0A5G2QWP9_PIG Isoform 1 of plus-end-directed kinesin ATPase OS=Sus scrofa OX=9823 GN=KIF1A PE=1 SV=2 CANONICAL=A0A5G2QWP9-1" }, "isoforms": [ { "isoform_ac": "A0A286ZS37-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9/entry#A0A286ZS37-1", "sequence": { "sequence": "MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETSVTTEKVSMASAGGGRGVRLGQEGANINKSLTTLGKVISALAEMNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGPGLRMLPGPPGLCPPLALGLAPRAPCCPTFATALLCVRFCQEGPGLDPPLLCLALQETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRWGSPGCRAGPPQRASAGTRPPAQPSVVTLEPCEGADTYVNGKKVTEPSVLRSGNRIIMGKSHVFRFNHPEQARQERERTPCAETPSEPVDWAFAQRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLVRAARRQAPTWDPGGRGPCLLFSRLWLQQLPSSQHMHERAHGCSHPLPHLLEPRLRRHRACRGAERGGGGGGGGGGGGPGGRRLSGARAVRRPGPVLRPAPPVQFSRKVGEVEDSMLGRNQLFCTGALLRAQFDRHQGVTPGDLGSSLDPGQRQAEGLASLGREREAGPGDGGGRVPRGEASAQWDSFCREAPGARQSRHAGPEGNTWQGGGAHRCAHRELSSSPPSALFQKRWREAPGPPPWEEEQTWRRPSRGQEGRAGAWAVKGPPSEALGTADPTLL", "length": 926, "header": "tr|A0A286ZS37-1|A0A5G2QWP9_PIG Computationally mapped isoform of plus-end-directed kinesin ATPase OS=Sus scrofa OX=9823 GN=KIF1A PE=1 SV=2 CANONICAL=A0A5G2QWP9-1" }, "locus": { "chromosome": "15", "start_pos": 139674853, "end_pos": 139646921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039711.2", "url": "https://www.ensembl.org/id/ENSSSCT00000039711.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034463.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034463.2" } ] } }, { "isoform_ac": "A0A5G2QTZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9/entry#A0A5G2QTZ0-1", "sequence": { "sequence": "MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETSVTTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDMTNALVGMSPSSSLSALSSRAASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGREDAEKRQDIVLSGHFIKEEHCVFRSDSRGGGEAVVTLEPCEGADTYVNGKKVTEPSVLRSGNRIIMGKSHVFRFNHPEQARQERERTPCAETPSEPVDWAFAQRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLDYESKLEALQKQMDSRYYPEVNEEEEEPEDEVQWTERECELALWAFRKWRWYQFTSLRDLLWGNAIFLKEANAISVELKKKVQFQFVLLTDTLYSPLPPDLLPPEAADRETRPFPRTIVAVEVQDQKNGATHYWTLEKLRQRLDLMREMYDRAAEVPSSVIEDCDNVVTGGDPFYDRFPWFRLVGSSVVSGCNSYPLLNTCMSERMAALTPSPTFSSPDSDATEPAEEQSVGEEEEEEEEEEDLEDDVFPEHVLCDGRDPFYDRPPLFSLVGRAFVYLSNLLYPVPLVHRVAIVSEKGEVKGFLRVAVQAISADEEAPDYGSGVRQSGTAKISFDDQHFEKFQSESCPGAGMSRSGASQEELRIVEGQGQGADAGPSADEVNNNTCSAVTPEGLLDSPEKATLDGPLDAALDHLGLGSTFTFRVTVLQASSISAEYADIFCQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAVEVTRSFIEYIKSQPIVFEVFGHYQQHPFPPLCKDVLSPLRPSRRHFPRVMPLSKPVPATKLSALTRHCPGPCHCKYDLLVYFEICELEANGDYIPAVVDHRGGMPCMGTFLLHQGIQRRITVTLLHETGSHIHWKEVRELVVGRIRNTPETDESLIDPNILSLNILSSGYIYPAQDDRTFYQFEAAWDSSMHNSLLLNRVTPYREKIYMTLSAYIEMENCTQPAVITKDFCMVFYSRDAKLPASRSIRNLFGSGSLRASESNRVTGVYELSLCHVADAGSPGTQRRRRRVLDTSVAYVRGEENLAGWRPRSDSLILDHQWELEKLSLLQEVEKTRHYLLLREKLETAQRPGPEALSPASSEDSEAHSSSSASSPLAAEGRPSSLEAPNERQRELAVKCLRLLTHSFNREYTHSHVCISASESKLSEMSVTLLRDPSMSPLGAATLTPSSTCPSLVEGRYGAPDLRTPQPCSRPASPEPEPLPEADSKKLPSPARGASEADKETPRLLVPDIQEIRVSPIVSKKGYLHFLEPHTAGWAKRFVVVRRPYAYMYNSDKDAVERFVLNLSTAQVEYSEDQQAMLKTPNTFAVCTEHRGILLQANSDKDMHDWLYAFNPLLAGTIRSKLSRRRSAQMRV", "length": 1776, "header": "tr|A0A5G2QTZ0-1|A0A5G2QWP9_PIG Computationally mapped isoform of plus-end-directed kinesin ATPase OS=Sus scrofa OX=9823 GN=KIF1A PE=1 SV=2 CANONICAL=A0A5G2QWP9-1" }, "locus": { "chromosome": "15", "start_pos": 139674853, "end_pos": 139613557, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067087.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067087.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065460.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065460.2" } ] } }, { "isoform_ac": "A0A5G2QUB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9/entry#A0A5G2QUB2-1", "sequence": { "sequence": "MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETSVTTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDTNTVPGGPKLTNALVGMSPSSSLSALSSRAASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGREDAEKRQDIVLSGHFIKEEHCVFRSDSRGGGEAVVTLEPCEGADTYVNGKKVTEPSVLRSGNRIIMGKSHVFRFNHPEQARQERERTPCAETPSEPVDWAFAQRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLDYESKLEALQKQMDSRYYPEVNEEEEEPEDEVQWTERECELALWAFRKWRWYQFTSLRDLLWGNAIFLKEANAISVELKKKVQFQFVLLTDTLYSPLPPDLLPPEAADRETRPFPRTIVAVEVQDQKNGATHYWTLEKLRQRLDLMREMYDRAAEVPSSVIEDCDNVVTGGDPFYDRFPWFRLVGSSVVSGCNSYPLLNTCMSERMAALTPSPTFSSPDSDATEPAEEQSVGEEEEEEEEEEDLEDDVFPEHVLCDGRDPFYDRPPLFSLVGRAFVYLSNLLYPVPLVHRVAIVSEKGEVKGFLRVAVQAISADEEAPDYGSGVRQSGTAKISFDDQHFEKFQSESCPGAGMSRSGASQEELRIVEGQGQGADAGPSADEVNNNTCSAVTPEGLLDSPEKATLDGPLDAALDHLGLGSTFTFRVTVLQASSISAEYADIFCQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAVEVTRSFIEYIKSQPIVFEVFGHYQQHPFPPLCKDVLSPLRPSRRHFPRVMPLSKPVPATKLSALTRHCPGPCHCKYDLLVYFEICELEANGDYIPAVVDHRGGMPCMGTFLLHQGIQRRITVTLLHETGSHIHWKEVRELVVGRIRNTPETDESLIDPNILSLNILSSGYIYPAQDDRVSFGGEPGTFYQFEAAWDSSMHNSLLLNRVTPYREKIYMTLSAYIEMENCTQPAVITKDFCMVFYSRDAKLPASRSIRNLFGSGSLRASESNRVTGVYELSLCHVADAGSPGTQRRRRRVLDTSVAYVRGEENLAGWRPRSDSLILDHQWELEKLSLLQEVEKTRHYLLLREKLETAQRPGPEALSPASSEDSEAHSSSSASSPLAAEGRPSSLEAPNERQRELAVKCLRLLTHSFNREYTHSHVCISASESKLSEMSVTLLRDPSMSPLGAATLTPSSTCPSLVEGRYGAPDLRTPQPCSRPASPEPEPLPEADSKKLPSPARGASEADKETPRLLVPDIQEIRVSPIVSKKGYLHFLEPHTAGWAKRFVVVRRPYAYMYNSDKDAVERFVLNLSTAQVEYSEDQQAMLKTPNTFAVCTEHRGILLQANSDKDMHDWLYAFNPLLAGTIRSKLSRRRSAQMRV", "length": 1793, "header": "tr|A0A5G2QUB2-1|A0A5G2QWP9_PIG Computationally mapped isoform of plus-end-directed kinesin ATPase OS=Sus scrofa OX=9823 GN=KIF1A PE=1 SV=2 CANONICAL=A0A5G2QWP9-1" }, "locus": { "chromosome": "15", "start_pos": 139674853, "end_pos": 139613557, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066907.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066907.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068526.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068526.2" } ] } }, { "isoform_ac": "A0A5G2QWP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9/entry#A0A5G2QWP9-1", "sequence": { "sequence": "MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETSVTTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDTNTVPGGPKLTNALVGMSPSSSLSALSSRAASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGREDAEKRQDIVLSGHFIKEEHCVFRSDSRGGGEAVVTLEPCEGADTYVNGKKVTEPSVLRSGNRIIMGKSHVFRFNHPEQARQERERTPCAETPSEPVDWAFAQRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLDYESKLEALQKQMDSRYYPEVNEEEEEPEDEVQWTERECELALWAFRKWRWYQFTSLRDLLWGNAIFLKEANAISVELKKKVQFQFVLLTDTLYSPLPPDLLPPEAADRETRPFPRTIVAVEVQDQKNGATHYWTLEKLRQRLDLMREMYDRAAEVPSSVIEDCDNVVTGGDPFYDRFPWFRLVGRAFVYLSNLLYPVPLVHRVAIVSEKGEVKGFLRVAVQAISADEEAPDYGSGVRQSGTAKISFDDQHFEKFQSESCPGAGMSRSGASQEELRIVEGQGQGADAGPSADEVNNNTCSAVTPEGLLDSPEKATLDGPLDAALDHLGLGSTFTFRVTVLQASSISAEYADIFCQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAVEVTRSFIEYIKSQPIVFEVFGHYQQHPFPPLCKDVLSPLRPSRRHFPRVMPLSKPVPATKLSALTRHCPGPCHCKYDLLVYFEICELEANGDYIPAVVDHRGGMPCMGTFLLHQGIQRRITVTLLHETGSHIHWKEVRELVVGRIRNTPETDESLIDPNILSLNILSSGYIYPAQDDRQFLDSDMPRTFYQFEAAWDSSMHNSLLLNRVTPYREKIYMTLSAYIEMENCTQPAVITKDFCMVFYSRDAKLPASRSIRNLFGSGSLRASESNRVTGVYELSLCHVADAGSPGTQRRRRRVLDTSVAYVRGEENLAGWRPRSDSLILDHQWELEKLSLLQEVEKTRHYLLLREKLETAQRPGPEALSPASSEDSEAHSSSSASSPLAAEGRPSSLEAPNERQRELAVKCLRLLTHSFNREYTHSHVCISASESKLSEMSVTLLRDPSMSPLGAATLTPSSTCPSLVEGRYGAPDLRTPQPCSRPASPEPEPLPEADSKKLPSPARGASEADKETPRLLVPDIQEIRVSPIVSKKGYLHFLEPHTAGWAKRFVVVRRPYAYMYNSDKDAVERFVLNLSTAQVEYSEDQQAMLKTPNTFAVCTEHRGILLQANSDKDMHDWLYAFNPLLAGTIRSKLSRRRSAQMRV", "length": 1707, "header": "tr|A0A5G2QWP9-1|A0A5G2QWP9_PIG Isoform 1 of plus-end-directed kinesin ATPase OS=Sus scrofa OX=9823 GN=KIF1A PE=1 SV=2 CANONICAL=A0A5G2QWP9-1" }, "locus": { "chromosome": "15", "start_pos": 139674853, "end_pos": 139613557, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072253.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072253.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066369.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066369.2" } ] } }, { "isoform_ac": "A0A5G2RE74-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9/entry#A0A5G2RE74-1", "sequence": { "sequence": "MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETSVTTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDTNTVPGGPKLTNALVGMSPSSSLSALSSRAASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGREDAEKRQDIVLSGHFIKEEHCVFRSDSRGGGEAVVTLEPCEGADTYVNGKKVTEPSVLRSGNRIIMGKSHVFRFNHPEQARQERERTPCAETPSEPVDWAFAQRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLDYESKLEALQKQMDSRYYPEVNEEEEEPEDEVQWTERECELALWAFRKWRWYQFTSLRDLLWGNAIFLKEANAISVELKKKVQFQFVLLTDTLYSPLPPDLLPPEAADRETRPFPRTIVAVEVQDQKNGATHYWTLEKLRQRLDLMREMYDRAAEVPSSVIEDCDNVVTGGDPFYDRFPWFRLVGRAFVYLSNLLYPVPLVHRVAIVSEKGEVKGFLRVAVQAISADEEAPDYGSGVRQSGTAKISFDDQHFEKFQSESCPGAGMSRSGASQEELRIVEGQGQGADAGPSADEVNNNTCSAVTPEGLLDSPEKATLDGPLDAALDHLGLGSTFTFRVTVLQASSISAEYADIFCQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAVEVTRSFIEYIKSQPIVFEVFGHYQQHPFPPLCKDVLSPLRPSRRHFPRVMPLSKPVPATKLSALTRHCPGPCHCKYDLLVYFEICELEANGDYIPAVVDHRGGMPCMGTFLLHQGIQRRITVTLLHETGSHIHWKEVRELVVGRIRNTPETDESLIDPNILSLNILSSGYIYPAQDDRTFYQFEAAWDSSMHNSLLLNRVTPYREKIYMTLSAYIEMENCTQPAVITKDFCMVFYSRDAKLPASRSIRNLFGSGSLRASESNRVTGVYELSLCHVADAGSPGTQRRRRRVLDTSVAYVRGEENLAGWRPRSDSLILDHQWELEKLSLLQEVEKTRHYLLLREKLETAQRPGPEALSPASSEDSEAHSSSSASSPLAAEGRPSSLEAPNERQRELAVKCLRLLTHSFNREYTHSHVCISASESKLSEMSVTLLRDPSMSPLGAATLTPSSTCPSLVEGRYGAPDLRTPQPCSRPASPEPEPLPEADSKKLPSPARGASEADKETPRLLVPDIQEIRVSPIVSKKGYLHFLEPHTAGWAKRFVVVRRPYAYMYNSDKDAVERFVLNLSTAQVEYSEDQQAMLKTPNTFAVCTEHRGILLQANSDKDMHDWLYAFNPLLAGTIRSKLSRRRSAQMRV", "length": 1698, "header": "tr|A0A5G2RE74-1|A0A5G2RE74_PIG Computationally mapped isoform of plus-end-directed kinesin ATPase OS=Sus scrofa OX=9823 GN=KIF1A PE=1 SV=2 CANONICAL=A0A5G2QWP9-1" }, "locus": { "chromosome": "15", "start_pos": 139674853, "end_pos": 139613557, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088069.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088069.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069127.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069127.2" } ] } }, { "isoform_ac": "F1SHW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9/entry#F1SHW6-1", "sequence": { "sequence": "MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETSVTTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDTNTVPGGPKLTNALVGMSPSSSLSALSSRAASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGREDAEKRQDIVLSGHFIKEEHCVFRSDSRGGGEAVVTLEPCEGADTYVNGKKVTEPSVLRSGNRIIMGKSHVFRFNHPEQARQERERTPCAETPSEPVDWAFAQRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLDYESKLEALQKQMDSRYYPEVNEEEEEPEDEVQWTERECELALWAFRKWRWYQFTSLRDLLWGNAIFLKEANAISVELKKKVQFQFVLLTDTLYSPLPPDLLPPEAADRETRPFPRTIVAVEVQDQKNGATHYWTLEKLRQRLDLMREMYDRAAEVPSSVIEDCDNVVTGGDPFYDRFPWFRLVGSSVVSGCNSYPLLNTCMSERMAALTPSPTFSSPDSDATEPAEEQSVGEEEEEEEEEEDLEDDVFPEHVLCDGRDPFYDRPPLFSLVGRAFVYLSNLLYPVPLVHRVAIVSEKGEVKGFLRVAVQAISADEEAPDYGSGVRQSGTAKISFDDQHFEKFQSESCPGAGMSRSGASQEELRIVEGQGQGADAGPSADEVNNNTCSAVTPEGLLDSPEKATLDGPLDAALDHLGLGSTFTFRVTVLQASSISAEYADIFCQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAVEVTRSFIEYIKSQPIVFEVFGHYQQHPFPPLCKDVLSPLRPSRRHFPRVMPLSKPVPATKLSALTRHCPGPCHCKYDLLVYFEICELEANGDYIPAVVDHRGGMPCMGTFLLHQGIQRRITVTLLHETGSHIHWKEVRELVVGRIRNTPETDESLIDPNILSLNILSSGYIYPAQDDRTFYQFEAAWDSSMHNSLLLNRVTPYREKIYMTLSAYIEMENCTQPAVITKDFCMVFYSRDAKLPASRSIRNLFGSGSLRASESNRVTGVYELSLCHVADAGSPGTQRRRRRVLDTSVAYVRGEENLAGWRPRSDSLILDHQWELEKLSLLQEVEKTRHYLLLREKLETAQRPGPEALSPASSEDSEAHSSSSASSPLAAEGRPSSLEAPNERQRELAVKCLRLLTHSFNREYTHSHVCISASESKLSEMSVTLLRDPSMSPLGAATLTPSSTCPSLVEGRYGAPDLRTPQPCSRPASPEPEPLPEADSKKLPSPARGASEADKETPRLLVPDIQEIRVSPIVSKKGYLHFLEPHTAGWAKRFVVVRRPYAYMYNSDKDAVERFVLNLSTAQVEYSEDQQAMLKTPNTFAVCTEHRGILLQANSDKDMHDWLYAFNPLLAGTIRSKLSRRRSAQMRV", "length": 1785, "header": "tr|F1SHW6-1|F1SHW6_PIG Computationally mapped isoform of plus-end-directed kinesin ATPase OS=Sus scrofa OX=9823 GN=KIF1A PE=1 SV=4 CANONICAL=A0A5G2QWP9-1" }, "locus": { "chromosome": "15", "start_pos": 139674853, "end_pos": 139613557, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017858.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017858.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017377.4", "url": "https://www.ensembl.org/id/ENSSSCP00000017377.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZS37", "url": "https://www.uniprot.org/uniprotkb/A0A286ZS37" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-SSC-983189", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983189", "resource": "Reactome", "description": "Kinesins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "transport along microtubule", "id": "GO:0010970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010970", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" }, { "name": "retrograde neuronal dense core vesicle transport", "id": "GO:1990049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990049", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1292, "end_pos": 1294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1637, "end_pos": 1639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 970, "end_pos": 972, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-6811423", "name": "Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6811423", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811423" } ] }, { "id": "R-SSC-6811426", "name": "Retrograde COPI vesicles bind kinesin and microtubules", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "transport vesicle", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6811426", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811426" } ] }, { "id": "R-SSC-983259", "name": "Kinesins move along microtubules consuming ATP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983259", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983259" } ] }, { "id": "R-SSC-983266", "name": "Kinesins bind microtubules", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983266", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983266" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWP9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1707, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWP9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWP9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" }, { "id": "PS50006", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50006" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FHA", "eco_id": "ECO_0000259", "start_pos": 525, "end_pos": 581, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QWP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" }, { "id": "PS50067", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kinesin motor", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 354, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QWP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP9" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 1592, "end_pos": 1690, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1292, "end_pos": 1294 }, { "start_pos": 131, "end_pos": 133 }, { "start_pos": 137, "end_pos": 139 }, { "start_pos": 1637, "end_pos": 1639 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 457, "end_pos": 459 }, { "start_pos": 970, "end_pos": 972 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QY27-1", "uniprot_ac": "A0A5G2QY27", "uniprot_id": "A0A5G2QY27_PIG", "mass": { "chemical_mass": 143198.0, "monoisotopic_mass": 143198.0 }, "refseq": { "ac": "XP_020935218", "name": "dystrophin isoform X15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935218" }, "gene_names": [ { "name": "DMD", "type": "recommended", "evidence": [ { "id": "A0A5G2QY27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ] }, { "name": "DMD", "type": "synonym", "evidence": [ { "id": "XP_020935218", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935218" } ] } ], "protein_names": [ { "name": "Dystrophin", "type": "recommended", "evidence": [ { "id": "A0A5G2QY27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27/entry#names_and_taxonomy" } ] }, { "name": "dystrophin isoform X15", "type": "synonym", "evidence": [ { "id": "XP_020935218", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935218" } ] } ], "function": [ { "annotation": "Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZSQ2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSQ2#function" }, { "database": "UniProtKB", "id": "ARBA00037032", "url": "https://www.uniprot.org/uniprotkb/ARBA00037032#function" }, { "database": "UniProtKB", "id": "F1SPU7", "url": "https://www.uniprot.org/uniprotkb/F1SPU7#function" }, { "database": "UniProtKB", "id": "I3LPH8", "url": "https://www.uniprot.org/uniprotkb/I3LPH8#function" }, { "database": "UniProtKB", "id": "I3LG08", "url": "https://www.uniprot.org/uniprotkb/I3LG08#function" }, { "database": "UniProtKB", "id": "A0A5G2QTV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTV4#function" }, { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27#function" }, { "database": "UniProtKB", "id": "A0A5G2R988", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R988#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DMD", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27", "locus": { "chromosome": "X", "start_pos": 27028231, "end_pos": 28383840, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000028148", "url": "https://www.ensembl.org/id/ENSSSCG00000028148" } ] } } ], "crossref": [ { "id": "A0A5G2QY27", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QY27", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000028148", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000028148", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00176", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00176", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02334", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02334", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16246", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16246", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "497636", "url": "https://www.ncbi.nlm.nih.gov/gene/497636", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12268", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12268", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12268:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12268:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00435", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00435", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09068", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09068", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-390522", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-390522", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9913351", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9913351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020935218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935218", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZSQ2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZSQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY27-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R988", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R988", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R988-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R988-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SPU7", "url": "https://www.uniprot.org/uniprotkb/F1SPU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SPU7-1", "url": "https://www.uniprot.org/uniprotkb/F1SPU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LG08", "url": "https://www.uniprot.org/uniprotkb/I3LG08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LG08-1", "url": "https://www.uniprot.org/uniprotkb/I3LG08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LPH8", "url": "https://www.uniprot.org/uniprotkb/I3LPH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LPH8-1", "url": "https://www.uniprot.org/uniprotkb/I3LPH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSSLLLEVPALADFNRAWTELTDWLSLLDRVIKSQRVMVGDLEDINEMIIKQKATLQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQSQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTMDAIQRKITETKQLAKDLRQWQINVDVANDLALKLLRDYSADDTRKVHMITENINASWANIHKRLSERETVLEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATHKERLLEDSKGVRELMKQWQDLQGEIEAHTDIYHNLDENGQKILRSLEGSDDAILLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDCPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDEALERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEMAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRIRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTVYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIVSLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSESMGEEDLLSPPQDTNTGLEEVMEQLNNSFPSSRGHNVGSLFHLADDLGRAMESLVSVMTDEEGAE", "length": 1243, "header": "tr|A0A5G2QY27-1|A0A5G2QY27_PIG Isoform 1 of Dystrophin OS=Sus scrofa OX=9823 GN=DMD PE=4 SV=1 CANONICAL=A0A5G2QY27-1" }, "isoforms": [ { "isoform_ac": "A0A286ZSQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27/entry#A0A286ZSQ2-1", "sequence": { "sequence": "MPSSLLLEVPALADFNRAWTELTDWLSLLDRVIKSQRVMVGDLEDINEMIIKQKATLQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQSQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTMDAIQRKITETKQLAKDLRQWQINVDVANDLALKLLRDYSADDTRKVHMITENINASWANIHKRLSERETVLEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATHKERLLEDSKGVRELMKQWQDLQGEIEAHTDIYHNLDENGQKILRSLEGSDDAILLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDCPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDEALERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEMAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRIRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTVYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIVSLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSESMGEEDLLSPPQDTNTGLEEVMEQLNNSFPSSRGRNTPGKPVREDTM", "length": 1115, "header": "tr|A0A286ZSQ2-1|A0A5G2QY27_PIG Computationally mapped isoform of Dystrophin OS=Sus scrofa OX=9823 GN=DMD PE=4 SV=1 CANONICAL=A0A5G2QY27-1" }, "locus": { "chromosome": "X", "start_pos": 27724125, "end_pos": 27030732, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048708.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048708.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034605.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034605.1" } ] } }, { "isoform_ac": "A0A5G2QTV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27/entry#A0A5G2QTV4-1", "sequence": { "sequence": "MPSSLLLEVPALADFNRAWTELTDWLSLLDRVIKSQRVMVGDLEDINEMIIKQKATLQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQSQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTMDAIQRKITETKQLAKDLRQWQINVDVANDLALKLLRDYSADDTRKVHMITENINASWANIHKRLSERETVLEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATHKERLLEDSKGVRELMKQWQDLQGEIEAHTDIYHNLDENGQKILRSLEGSDDAILLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDCPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDEALERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEMAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRIRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTVYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIVSLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQKKYPWEASERGHNVGSLFHLADDLGRAMESLVSVMTDEEGAE", "length": 1154, "header": "tr|A0A5G2QTV4-1|A0A5G2QY27_PIG Computationally mapped isoform of Dystrophin OS=Sus scrofa OX=9823 GN=DMD PE=4 SV=2 CANONICAL=A0A5G2QY27-1" }, "locus": { "chromosome": "X", "start_pos": 27724125, "end_pos": 27030646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089893.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089893.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068371.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068371.2" } ] } }, { "isoform_ac": "A0A5G2QY27-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27/entry#A0A5G2QY27-1", "sequence": { "sequence": "MPSSLLLEVPALADFNRAWTELTDWLSLLDRVIKSQRVMVGDLEDINEMIIKQKATLQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQSQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTMDAIQRKITETKQLAKDLRQWQINVDVANDLALKLLRDYSADDTRKVHMITENINASWANIHKRLSERETVLEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATHKERLLEDSKGVRELMKQWQDLQGEIEAHTDIYHNLDENGQKILRSLEGSDDAILLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDCPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDEALERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEMAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRIRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTVYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIVSLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSESMGEEDLLSPPQDTNTGLEEVMEQLNNSFPSSRGHNVGSLFHLADDLGRAMESLVSVMTDEEGAE", "length": 1243, "header": "tr|A0A5G2QY27-1|A0A5G2QY27_PIG Isoform 1 of Dystrophin OS=Sus scrofa OX=9823 GN=DMD PE=4 SV=1 CANONICAL=A0A5G2QY27-1" }, "locus": { "chromosome": "X", "start_pos": 27724125, "end_pos": 27030646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087025.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087025.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066851.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066851.1" } ] } }, { "isoform_ac": "A0A5G2R988-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27/entry#A0A5G2R988-1", "sequence": { "sequence": "MPSSLLLEVPALADFNRAWTELTDWLSLLDRVIKSQRVMVGDLEDINEMIIKQKATLQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQSQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTMDAIQRKITETKQLAKDLRQWQINVDVANDLALKLLRDYSADDTRKVHMITENINASWANIHKRLSERETVLEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATHKERLLEDSKGVRELMKQWQDLQGEIEAHTDIYHNLDENGQKILRSLEGSDDAILLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDCPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDEALERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEMAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRIRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTVYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIVSLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSESMGEEDLLSPPQDTNTGLEEVMEQLNNSFPSSRGRNTPGKPVREDTM", "length": 1212, "header": "tr|A0A5G2R988-1|A0A5G2R988_PIG Computationally mapped isoform of Dystrophin OS=Sus scrofa OX=9823 GN=DMD PE=4 SV=2 CANONICAL=A0A5G2QY27-1" }, "locus": { "chromosome": "X", "start_pos": 27724125, "end_pos": 27030732, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071618.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071618.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072889.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072889.2" } ] } }, { "isoform_ac": "F1SPU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27/entry#F1SPU7-1", "sequence": { "sequence": "MQQDQCCSPRFKLKMLHRKTYHVKDLQGEIEAHTDIYHNLDENGQKILRSLEGSDDAILLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDCPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDEALERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEMAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRIRQLHEAHRDFGPASQHFLSTPDRGALAAMREQLKGHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTVYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIVSLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSESMGEEDLLSPPQDTNTGLEEVMEQLNNSFPSSRGRNTPGKPVREDTM", "length": 965, "header": "tr|F1SPU7-1|A0A5G2QY27_PIG Computationally mapped isoform of Dystrophin OS=Sus scrofa OX=9823 GN=DMD PE=4 SV=6 CANONICAL=A0A5G2QY27-1" }, "locus": { "chromosome": "X", "start_pos": 27422787, "end_pos": 27030732, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013350.6", "url": "https://www.ensembl.org/id/ENSSSCT00000013350.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012992.6", "url": "https://www.ensembl.org/id/ENSSSCP00000012992.6" } ] } }, { "isoform_ac": "I3LG08-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27/entry#I3LG08-1", "sequence": { "sequence": "MSGRKLRNLSYKKAVRRQKLLEQSIQSAQEIEKSLHLIQDSLSSIDHQLAVYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKKHYQGKEAAPRVLSQIELAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALEIKSVEQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDTELTKRSAVEGMPSNLDSEVVWGKATQKEIEKQKFHLKSISEIGEALKMVLGKKETLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMENFDQNVDHITKWIIQADTLLDESEKKKPQQKEDVLKRLKAEMNDMRPKVDSTRDQAANLMANRGDHCRKVIEPKISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKDMSEDNEGTVKELLQRGDNLQQRITDERKREEIKIKQQLLQTKHNALKDLRSQRRKKALEISHQWYQYKRQADDLLKCLDDIEKKLASLPEPQDEKKIKEIDRELQKKKEELDAVRRQAEGLSEDGAAMAVEPTQIQLSKRWREIESKFAHFRRLNFAQIHTVHEESVMVMTEDMPLEISYVPSAYLTEITHVSQALSEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQISGRVDIIHNKKTAGLQSATPVERTRLQEALSQLDFQWERVNKMYKDRQGKFDRSVEKWRRFHYDMKIFNQWLTEAEHFLKKTQIPENWEHAKYKWYLKELQDGIGQRQTIVRVLNATGEEVIQQSSKTDASILQEKLGSLNLRWQEVCKQLAERKKRLEEQKNILSEFQRDLNEFVLWLEEADNITSVALEPGNEQQLKEKLEEIKLLAEELPLRQGILKQLNETGGTVLVSAPISPEEQDKIENKLKQTNLQWIKVSRILPEKQGEIEAHIKDLGQLEEQLNHLLVWLSPIKNQLEIYNQPNQTGPFDIKETEVAVQAKQPDVEGILSKGQHLYKEKPATQPVKRKLEDLSSEWKAVTHLLQELRAKWPGPTPGLTTIEAPTSQTVTLVTQPTVTKETAISKPEMPSSLLLEVPALADFNRAWTELTDWLSLLDRVIKSQRVMVGDLEDINEMIIKQKATLQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQSQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTMDAIQRKITETKQLAKDLRQWQINVDVANDLALKLLRDYSADDTRKVHMITENINASWANIHKRLSERETVLEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATHKERLLEDSKGVRELMKQWQDLQGEIEAHTDIYHNLDENGQKILRSLEGSDDAILLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDCPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDEALERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEMAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRIRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTVYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIVSLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSESMGEEDLLSPPQDTNTGLEEVMEQLNNSFPSSRGRNTPGKPVREDTM", "length": 2334, "header": "tr|I3LG08-1|A0A5G2QY27_PIG Computationally mapped isoform of Dystrophin OS=Sus scrofa OX=9823 GN=DMD PE=4 SV=5 CANONICAL=A0A5G2QY27-1" }, "locus": { "chromosome": "X", "start_pos": 28383840, "end_pos": 27030732, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026041.5", "url": "https://www.ensembl.org/id/ENSSSCT00000026041.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023001.5", "url": "https://www.ensembl.org/id/ENSSSCP00000023001.5" } ] } }, { "isoform_ac": "I3LPH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27/entry#I3LPH8-1", "sequence": { "sequence": "MQQDQCCSPRFKLKMLHRKTYHVKDLQGEIEAHTDIYHNLDENGQKILRSLEGSDDAILLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDCPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDEALERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEMAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRIRQLHEAHRDFGPASQHFLSTPDRGALAAMREQLKGHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTVYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIVSLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSESMGEEDLLSPPQDTNTGLEEVMEQLNNSFPSSRGRNTPGKPVREDTM", "length": 930, "header": "tr|I3LPH8-1|A0A5G2QY27_PIG Computationally mapped isoform of Dystrophin OS=Sus scrofa OX=9823 GN=DMD PE=4 SV=4 CANONICAL=A0A5G2QY27-1" }, "locus": { "chromosome": "X", "start_pos": 27422787, "end_pos": 27030732, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029079.4", "url": "https://www.ensembl.org/id/ENSSSCT00000029079.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026005.4", "url": "https://www.ensembl.org/id/ENSSSCP00000026005.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SPU7", "url": "https://www.uniprot.org/uniprotkb/F1SPU7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-390522", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-390522", "resource": "Reactome", "description": "Striated Muscle Contraction" }, { "id": "R-SSC-9913351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9913351", "resource": "Reactome", "description": "Formation of the dystrophin-glycoprotein complex (DGC)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "dystrophin-associated glycoprotein complex", "id": "GO:0016010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016010", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "cell-substrate junction", "id": "GO:0030055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030055", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "neuron projection terminus", "id": "GO:0044306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044306", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "postsynaptic specialization", "id": "GO:0099572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099572", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "nitric-oxide synthase binding", "id": "GO:0050998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050998", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "regulation of heart rate", "id": "GO:0002027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002027", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "id": "GO:0010881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010881", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "regulation of sodium ion transmembrane transport", "id": "GO:1902305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902305", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "cardiac muscle cell action potential", "id": "GO:0086001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086001", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "muscle cell development", "id": "GO:0055001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055001", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "positive regulation of cell-matrix adhesion", "id": "GO:0001954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001954", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion", "id": "GO:0014809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014809", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "regulation of muscle system process", "id": "GO:0090257", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090257", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" }, { "name": "synaptic signaling", "id": "GO:0099536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099536", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1002, "end_pos": 1004, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1147, "end_pos": 1149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1204, "end_pos": 1206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" }, { "start_pos": 991, "end_pos": 993, "annotation": "n_glycosylation_sequon" }, { "start_pos": 996, "end_pos": 998, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QY27-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1243, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QY27-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QY27" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QY27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 595, "end_pos": 628, "start_aa": "Thr", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QY27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY27" }, { "id": "PS50135", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50135" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZZ-type", "eco_id": "ECO_0000259", "start_pos": 848, "end_pos": 904, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1002, "end_pos": 1004 }, { "start_pos": 1147, "end_pos": 1149 }, { "start_pos": 1204, "end_pos": 1206 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 79, "end_pos": 81 }, { "start_pos": 991, "end_pos": 993 }, { "start_pos": 996, "end_pos": 998 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R496-1", "uniprot_ac": "A0A5G2R496", "uniprot_id": "A0A5G2R496_PIG", "mass": { "chemical_mass": 39721.0, "monoisotopic_mass": 39721.0 }, "refseq": { "ac": "XP_005666097", "name": "DNA-directed RNA polymerases I and III subunit RPAC1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666097" }, "gene_names": [ { "name": "POLR1C", "type": "recommended", "evidence": [ { "id": "A0A5G2R496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ] }, { "name": "POLR1C", "type": "synonym", "evidence": [ { "id": "XP_005666097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666097" } ] } ], "protein_names": [ { "name": "DNA-directed RNA polymerases I and III subunit RPAC1", "type": "recommended", "evidence": [ { "id": "A0A5G2R496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496/entry#names_and_taxonomy" } ] }, { "name": "DNA-directed RNA polymerases I and III subunit RPAC1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005666097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666097" } ] } ], "function": [ { "annotation": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and short non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs, respectively. POLR1C/RPAC1 is part of the polymerase core and may function as a clamp element that moves to open and close the cleft.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496#function" }, { "database": "UniProtKB", "id": "ARBA00056177", "url": "https://www.uniprot.org/uniprotkb/ARBA00056177#function" }, { "database": "UniProtKB", "id": "A0A286ZT79", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT79#function" }, { "database": "UniProtKB", "id": "A0A286ZY98", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY98#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "POLR1C", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496", "locus": { "chromosome": "7", "start_pos": 38537943, "end_pos": 38507073, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000028007", "url": "https://www.ensembl.org/id/ENSSSCG00000028007" } ] } } ], "crossref": [ { "id": "A0A5G2R496", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R496", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000028007", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000028007", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07032", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07032", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "414414", "url": "https://www.ncbi.nlm.nih.gov/gene/414414", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001514", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001514", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011262", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011262", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:414414", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414414", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFPEVVF", "url": "https://omabrowser.org/oma/group/MFPEVVF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZY98", "url": "https://www.orthodb.org/?gene=A0A286ZY98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R496", "url": "https://www.orthodb.org/?gene=A0A5G2R496", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11800", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11800", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11800:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11800:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5250924", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5250924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73762", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73762", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73772", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73772", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73863", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73863", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-76061", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76061", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-76066", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-76071", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76071", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005666097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666097", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZT79", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZT79-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZY98", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZY98-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ22-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R496-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R518", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R518", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R518-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R518-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVELKMAAAQAVEEMRSRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNLGDEEGTEIDTLQFRLQVRCTRNPSAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMQCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGDAAEELSRCFSPGVIEVQEIQGKKVARVANPRLDTFSREVFRNDMLKKVVRLARVRDHYIFSVESTGVLPPDVLVSEAIKVLMGKCRRFLDELDAVQMD", "length": 351, "header": "tr|A0A5G2R496-1|A0A5G2R496_PIG Isoform 1 of DNA-directed RNA polymerases I and III subunit RPAC1 OS=Sus scrofa OX=9823 GN=POLR1C PE=1 SV=1 CANONICAL=A0A5G2R496-1" }, "isoforms": [ { "isoform_ac": "A0A286ZT79-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496/entry#A0A286ZT79-1", "sequence": { "sequence": "MGTPISHVLNEWKVKTRSLSQKLMKDWRRKKHPNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNLGDEEGTEIDTLQFRLQVRCTRNPSAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMQCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGDAAEELSRCFSPGVIEVQEIQGKKVARVANPRLDTFSREVFRNDMLKKVVRLARVRDHYIFSVESTGVLPPDVLVSEAIKVLMGKCRRFLDELDAVQMD", "length": 332, "header": "tr|A0A286ZT79-1|A0A5G2R496_PIG Computationally mapped isoform of DNA-directed RNA polymerases I and III subunit RPAC1 OS=Sus scrofa OX=9823 GN=POLR1C PE=1 SV=2 CANONICAL=A0A5G2R496-1" }, "locus": { "chromosome": "7", "start_pos": 38530588, "end_pos": 38528501, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060718.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060718.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034852.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034852.2" } ] } }, { "isoform_ac": "A0A286ZY98-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496/entry#A0A286ZY98-1", "sequence": { "sequence": "MNLASLLLREQNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNLGDEEGTEIDTLQFRLQVRCTRNPSAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMQCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGDAAEELSRCFSPGVIEVQEIQGKKVARVANPRLDTFSREVFRNDMLKKVVRLARVRDHYIFSVESTGVLPPDVLVSEAIKVLMGKCRRFLDELDAVQMD", "length": 310, "header": "tr|A0A286ZY98-1|A0A5G2R496_PIG Computationally mapped isoform of DNA-directed RNA polymerases I and III subunit RPAC1 OS=Sus scrofa OX=9823 GN=POLR1C PE=1 SV=1 CANONICAL=A0A5G2R496-1" }, "locus": { "chromosome": "7", "start_pos": 38530588, "end_pos": 38511741, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040334.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040334.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036691.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036691.1" } ] } }, { "isoform_ac": "A0A5G2QQ22-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496/entry#A0A5G2QQ22-1", "sequence": { "sequence": "MVELKMAAAQAVEEMRSRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNLGDEEGTEIDTLQFRLQVRCTRNPSAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMQCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGDAAEELSRCFSPGVIEVQEIQGKKVARVANPRLDTFSREVFRNDMLKKVVRLARVRDHYIWKKN", "length": 316, "header": "tr|A0A5G2QQ22-1|A0A5G2R496_PIG Computationally mapped isoform of DNA-directed RNA polymerases I and III subunit RPAC1 OS=Sus scrofa OX=9823 GN=POLR1C PE=1 SV=2 CANONICAL=A0A5G2R496-1" }, "locus": { "chromosome": "7", "start_pos": 38537943, "end_pos": 38511585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087037.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087037.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060387.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060387.2" } ] } }, { "isoform_ac": "A0A5G2R496-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496/entry#A0A5G2R496-1", "sequence": { "sequence": "MVELKMAAAQAVEEMRSRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNLGDEEGTEIDTLQFRLQVRCTRNPSAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMQCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGDAAEELSRCFSPGVIEVQEIQGKKVARVANPRLDTFSREVFRNDMLKKVVRLARVRDHYIFSVESTGVLPPDVLVSEAIKVLMGKCRRFLDELDAVQMD", "length": 351, "header": "tr|A0A5G2R496-1|A0A5G2R496_PIG Isoform 1 of DNA-directed RNA polymerases I and III subunit RPAC1 OS=Sus scrofa OX=9823 GN=POLR1C PE=1 SV=1 CANONICAL=A0A5G2R496-1" }, "locus": { "chromosome": "7", "start_pos": 38530588, "end_pos": 38511585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086396.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086396.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065382.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065382.1" } ] } }, { "isoform_ac": "A0A5G2R518-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496/entry#A0A5G2R518-1", "sequence": { "sequence": "MVELKMAAAQAVEEMRSRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNLGDEEGTEIDTLQFRLQVRCTRNPSAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMQCVKGIGKKVARVANPRLDTFSREVFRNDMLKKVVRLARVRDHYIFSVESTGVLPPDVLVSEAIKVLMGKCRRFLDELDAVQMD", "length": 301, "header": "tr|A0A5G2R518-1|A0A5G2R518_PIG Computationally mapped isoform of DNA-directed RNA polymerases I and III subunit RPAC1 OS=Sus scrofa OX=9823 GN=POLR1C PE=1 SV=2 CANONICAL=A0A5G2R496-1" }, "locus": { "chromosome": "7", "start_pos": 38530588, "end_pos": 38511585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075419.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075419.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072319.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072319.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT79", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT79" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:414414", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414414", "resource": "KEGG Pathway" }, { "id": "R-SSC-5250924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5250924", "resource": "Reactome", "description": "B-WICH complex positively regulates rRNA expression" }, { "id": "R-SSC-73762", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73762", "resource": "Reactome", "description": "RNA Polymerase I Transcription Initiation" }, { "id": "R-SSC-73772", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73772", "resource": "Reactome", "description": "RNA Polymerase I Promoter Escape" }, { "id": "R-SSC-73863", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73863", "resource": "Reactome", "description": "RNA Polymerase I Transcription Termination" }, { "id": "R-SSC-76061", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76061", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 1 Promoter" }, { "id": "R-SSC-76066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76066", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 2 Promoter" }, { "id": "R-SSC-76071", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76071", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 3 Promoter" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase activity", "id": "GO:0003899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003899", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" }, { "name": "RNA polymerase I complex", "id": "GO:0005736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005736", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase complex", "id": "GO:0000428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000428", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" }, { "name": "RNA polymerase III complex", "id": "GO:0005666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005666", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase I", "id": "GO:0006362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006362", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" }, { "name": "termination of RNA polymerase III transcription", "id": "GO:0006386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006386", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R496", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R496-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 351, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R496-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R496" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R496" }, { "id": "SM00662", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00662" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DNA-directed RNA polymerase RpoA/D/Rpb3-type", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 344, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 102, "end_pos": 104 }, { "start_pos": 37, "end_pos": 39 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXA1-1", "uniprot_ac": "A0A5G2QXA1", "uniprot_id": "A0A5G2QXA1_PIG", "mass": { "chemical_mass": 62449.0, "monoisotopic_mass": 62449.0 }, "refseq": { "ac": "XP_020937367", "name": "natural resistance-associated macrophage protein 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937367" }, "gene_names": [ { "name": "SLC11A2", "type": "recommended", "evidence": [ { "id": "A0A5G2QXA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ] }, { "name": "DMT1", "type": "synonym", "evidence": [ { "id": "XP_020937367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937367" } ] }, { "name": "SLC11A2", "type": "synonym", "evidence": [ { "id": "XP_020937367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937367" } ] } ], "protein_names": [ { "name": "Solute carrier family 11 member 2", "type": "synonym", "evidence": [ { "id": "A0A5G2QXA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1/entry#names_and_taxonomy" } ] }, { "name": "natural resistance-associated macrophage protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_020937367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937367" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC11A2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1", "locus": {} } ], "crossref": [ { "id": "A0A5G2QXA1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXA1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034039", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034039", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "733595", "url": "https://www.ncbi.nlm.nih.gov/gene/733595", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11706", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11706", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11706:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11706:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-425410", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-425410", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-917937", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917937", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020937367", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937367", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZVW1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZVW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYV6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIX1", "url": "https://www.uniprot.org/uniprotkb/A0A287BIX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BIX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BKX2", "url": "https://www.uniprot.org/uniprotkb/A0A287BKX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BKX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BKX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLE8", "url": "https://www.uniprot.org/uniprotkb/A0A287BLE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BLE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QCN0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QCN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLGPEQKTPSEDASGEHGDTASLGAINPAYSHSSLPQSPGGLSEEPFTTYFDEKIAIPEEEHSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITVMALTFGYEYVTVKPSQSQVLKGMFLPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKEEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNQQVVDVCRNSSSPHSDLFPEDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFANGIGWRIAGGILVLIVCSINMYFVVVYVQDLGHVVLYVVAAVVSVAYLSFVFYLGWQCLIALGMSFLDCGHTYHLGLTVQPELYLLNTVDADSLVSR", "length": 569, "header": "tr|A0A5G2QXA1-1|A0A5G2QXA1_PIG Isoform 1 of Solute carrier family 11 member 2 OS=Sus scrofa OX=9823 GN=SLC11A2 PE=3 SV=2 CANONICAL=A0A5G2QXA1-1" }, "isoforms": [ { "isoform_ac": "A0A286ZVW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1/entry#A0A286ZVW1-1", "sequence": { "sequence": "MKKGKKEAAPCCELKSYSKNSGTQVSAMVLGPEQKTPSEDASGEHGDTASLGAINPAYSHSSLPQSPGGLSEEPFTTYFDEKIAIPEEEHSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITVMALTFGYEYVTVKPSQSQVLKGMFLPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKEEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNQQVVDVCRNSSSPHSDLFPEDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFANGIGWRIAGGILVLIVCSINMYFVVVYVQDLGHVVLYVVAAVVSVAYLSFVFYLGWQCLIALGMSFLDCGHTVSISKALLTEEATSGYAK", "length": 579, "header": "tr|A0A286ZVW1-1|A0A5G2QXA1_PIG Computationally mapped isoform of Solute carrier family 11 member 2 OS=Sus scrofa OX=9823 GN=SLC11A2 PE=3 SV=2 CANONICAL=A0A5G2QXA1-1" }, "locus": { "chromosome": "AEMK02000258.1", "start_pos": 369836, "end_pos": 341472, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050069.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050069.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035756.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035756.2" } ] } }, { "isoform_ac": "A0A286ZYV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1/entry#A0A286ZYV6-1", "sequence": { "sequence": "MVLGPEQKTPSEDASGEHGDTASLGAINPAYSHSSLPQSPGGLSEEPFTTYFDEKIAIPEEEHSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITVMALTFGYEYVTVKPSQSQVLKGMFLPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKEEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNQQVVDVCRNSSSPHSDLFPEDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFANGIGWRIAGGILVLIVCSINMYFVVVYVQDLGHVVLYVVAAVVSVAYLSFVFYLGWQCLIALGMSFLDCGHTDL", "length": 546, "header": "tr|A0A286ZYV6-1|A0A5G2QXA1_PIG Computationally mapped isoform of Solute carrier family 11 member 2 OS=Sus scrofa OX=9823 GN=SLC11A2 PE=3 SV=3 CANONICAL=A0A5G2QXA1-1" }, "locus": { "chromosome": "AEMK02000258.1", "start_pos": 370057, "end_pos": 354928, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043790.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043790.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036893.3", "url": "https://www.ensembl.org/id/ENSSSCP00000036893.3" } ] } }, { "isoform_ac": "A0A287BIX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1/entry#A0A287BIX1-1", "sequence": { "sequence": "YVLSPEDIKDASGEHGDTASLGAINPAYSHSSLPQSPGGLSEEPFTTYFDEKIAIPEEEHSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITVMALTFGYEYVTVKPSQSQVLKGMFLPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKEEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNQQVVDVCRNSSSPHSDLFPEDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFANGIGWRIAGGILVLIVCSINMYFVVVYVQDLGHVVLYVVAAVVSVAYLSFVFYLGWQCLIALGMSFLDCGHTVSISKALLTEEATSGYAK", "length": 559, "header": "tr|A0A287BIX1-1|A0A5G2QXA1_PIG Computationally mapped isoform of Solute carrier family 11 member 2 OS=Sus scrofa OX=9823 GN=SLC11A2 PE=3 SV=2 CANONICAL=A0A5G2QXA1-1" }, "locus": { "chromosome": "AEMK02000258.1", "start_pos": 369836, "end_pos": 356023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059222.2", "url": "https://www.ensembl.org/id/ENSSSCT00000059222.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056318.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056318.2" } ] } }, { "isoform_ac": "A0A287BKX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1/entry#A0A287BKX2-1", "sequence": { "sequence": "MKVKSYSKNSGTQVSAMVLGPEQKTPSEDASGEHGDTASLGAINPAYSHSSLPQSPGGLSEEPFTTYFDEKIAIPEEEHSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITVMALTFGYEYVTVKPSQSQVLKGMFLPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKEEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNQQVVDVCRNSSSPHSDLFPEDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFANGIGWRIAGGILVLIVCSINMYFVVVYVQDLGHVVLYVVAAVVSVAYLSFVFYLGWQCLIALGMSFLDCGHTVSISKALLTEEATSGYAK", "length": 578, "header": "tr|A0A287BKX2-1|A0A5G2QXA1_PIG Computationally mapped isoform of Solute carrier family 11 member 2 OS=Sus scrofa OX=9823 GN=SLC11A2 PE=3 SV=3 CANONICAL=A0A5G2QXA1-1" }, "locus": { "chromosome": "AEMK02000258.1", "start_pos": 369836, "end_pos": 344649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042375.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042375.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057157.3", "url": "https://www.ensembl.org/id/ENSSSCP00000057157.3" } ] } }, { "isoform_ac": "A0A287BLE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1/entry#A0A287BLE8-1", "sequence": { "sequence": "MLLENMGTRPVLVPSTLLTVTPLSRSRPGGSQRSPSPPTLTRRSPFLRRRFVTGPWEETLVSRGNLGVKRLLDNSRSTAHSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITVMALTFGYEYVTVKPSQSQVLKGMFLPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKEEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNQQVVDVCRNSSSPHSDLFPEDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFANGIGWRIAGGILVLIVCSINMYFVVVYVQDLGHVVLYVVAAVVSVAYLSFVFYLGWQCLIALGMSFLDCGHTYHLGLTVQPELYLLNTVDADSLVSR", "length": 586, "header": "tr|A0A287BLE8-1|A0A5G2QXA1_PIG Computationally mapped isoform of Solute carrier family 11 member 2 OS=Sus scrofa OX=9823 GN=SLC11A2 PE=3 SV=3 CANONICAL=A0A5G2QXA1-1" }, "locus": { "chromosome": "AEMK02000258.1", "start_pos": 375971, "end_pos": 356435, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047355.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047355.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057340.3", "url": "https://www.ensembl.org/id/ENSSSCP00000057340.3" } ] } }, { "isoform_ac": "A0A5G2QCN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1/entry#A0A5G2QCN0-1", "sequence": { "sequence": "MSQDDSFKDASGEHGDTASLGAINPAYSHSSLPQSPGGLSEEPFTTYFDEKIAIPEEEHSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITVMALTFGYEYVTVKPSQSQVLKGMFLPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKEEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNQQVVDVCRNSSSPHSDLFPEDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFANGIGWRIAGGILVLIVCSINMYFVVVYVQDLGHVVLYVVAAVVSVAYLSFVFYLGWQCLIALGMSFLDCGHTVSISKALLTEEATSGYAK", "length": 548, "header": "tr|A0A5G2QCN0-1|A0A5G2QCN0_PIG Computationally mapped isoform of Solute carrier family 11 member 2 OS=Sus scrofa OX=9823 GN=SLC11A2 PE=3 SV=1 CANONICAL=A0A5G2QXA1-1" }, "locus": { "chromosome": "AEMK02000258.1", "start_pos": 369836, "end_pos": 355890, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080393.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080393.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061865.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061865.1" } ] } }, { "isoform_ac": "A0A5G2QXA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1/entry#A0A5G2QXA1-1", "sequence": { "sequence": "MVLGPEQKTPSEDASGEHGDTASLGAINPAYSHSSLPQSPGGLSEEPFTTYFDEKIAIPEEEHSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITVMALTFGYEYVTVKPSQSQVLKGMFLPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKEEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNQQVVDVCRNSSSPHSDLFPEDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFANGIGWRIAGGILVLIVCSINMYFVVVYVQDLGHVVLYVVAAVVSVAYLSFVFYLGWQCLIALGMSFLDCGHTYHLGLTVQPELYLLNTVDADSLVSR", "length": 569, "header": "tr|A0A5G2QXA1-1|A0A5G2QXA1_PIG Isoform 1 of Solute carrier family 11 member 2 OS=Sus scrofa OX=9823 GN=SLC11A2 PE=3 SV=2 CANONICAL=A0A5G2QXA1-1" }, "locus": { "chromosome": "AEMK02000258.1", "start_pos": 375971, "end_pos": 354928, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080368.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080368.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069564.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069564.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVW1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVW1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-425410", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-425410", "resource": "Reactome", "description": "Metal ion SLC transporters" }, { "id": "R-SSC-917937", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917937", "resource": "Reactome", "description": "Iron uptake and transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 13, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "basal part of cell", "id": "GO:0045178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045178", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "extracellular vesicle", "id": "GO:1903561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903561", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "paraferritin complex", "id": "GO:0070826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070826", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "iron ion transmembrane transport", "id": "GO:0034755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034755", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "response to iron ion", "id": "GO:0010039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010039", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "manganese ion transport", "id": "GO:0006828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006828", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "intracellular manganese ion homeostasis", "id": "GO:0030026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030026", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "multicellular organismal-level iron ion homeostasis", "id": "GO:0060586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060586", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "metal ion transmembrane transporter activity", "id": "GO:0046873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046873", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "cadmium ion binding", "id": "GO:0046870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046870", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "solute:proton symporter activity", "id": "GO:0015295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015295", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "copper ion transmembrane transporter activity", "id": "GO:0005375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005375", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "manganese ion transmembrane transporter activity", "id": "GO:0005384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005384", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "cadmium ion transmembrane transporter activity", "id": "GO:0015086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015086", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "cobalt ion transmembrane transporter activity", "id": "GO:0015087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "ferrous iron transmembrane transporter activity", "id": "GO:0015093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015093", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "lead ion transmembrane transporter activity", "id": "GO:0015094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015094", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" }, { "name": "nickel cation transmembrane transporter activity", "id": "GO:0015099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015099", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXA1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QXA1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 569, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QXA1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXA1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 337, "end_pos": 339 }, { "start_pos": 350, "end_pos": 352 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R276-1", "uniprot_ac": "A0A5G2R276", "uniprot_id": "A0A5G2R276_PIG", "mass": { "chemical_mass": 21352.0, "monoisotopic_mass": 21352.0 }, "refseq": {}, "gene_names": [ { "name": "VAMP2", "type": "recommended", "evidence": [ { "id": "A0A5G2R276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" } ] } ], "protein_names": [ { "name": "Vesicle associated membrane protein 2", "type": "synonym", "evidence": [ { "id": "A0A5G2R276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R276", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "VAMP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276", "locus": { "chromosome": "12", "start_pos": 53378409, "end_pos": 53382240, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034868", "url": "https://www.ensembl.org/id/ENSSSCG00000034868" } ] } } ], "crossref": [ { "id": "A0A5G2R276", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R276", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034868", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034868", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15870", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15870", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45701", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45701", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00957", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00957", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-181429", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-181429", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-181430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-181430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-199992", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-199992", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-210500", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-210500", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-212676", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-264642", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264642", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-432720", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432720", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-449836", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-449836", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-888590", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-888590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9609523", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9609523", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZY50", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZY50-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R276", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R276-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QAGKLRPGGGRGPPSRSRGRLPAGPGEGHGSLRVALLPRRRKGGTDGWTDGWAEPSLRGRGLQGLDLNPSVPLRSATAATAPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIGESGGSGRAPLLERFPP", "length": 201, "header": "tr|A0A5G2R276-1|A0A5G2R276_PIG Isoform 1 of Vesicle associated membrane protein 2 OS=Sus scrofa OX=9823 GN=VAMP2 PE=1 SV=2 CANONICAL=A0A5G2R276-1" }, "isoforms": [ { "isoform_ac": "A0A286ZY50-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276/entry#A0A286ZY50-1", "sequence": { "sequence": "MSATAATAPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIGESGGSGRAPLLERFPP", "length": 128, "header": "tr|A0A286ZY50-1|A0A5G2R276_PIG Computationally mapped isoform of Vesicle associated membrane protein 2 OS=Sus scrofa OX=9823 GN=VAMP2 PE=1 SV=2 CANONICAL=A0A5G2R276-1" }, "locus": { "chromosome": "12", "start_pos": 53382102, "end_pos": 53380673, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042111.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042111.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036563.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036563.2" } ] } }, { "isoform_ac": "A0A5G2R276-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276/entry#A0A5G2R276-1", "sequence": { "sequence": "QAGKLRPGGGRGPPSRSRGRLPAGPGEGHGSLRVALLPRRRKGGTDGWTDGWAEPSLRGRGLQGLDLNPSVPLRSATAATAPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIGESGGSGRAPLLERFPP", "length": 201, "header": "tr|A0A5G2R276-1|A0A5G2R276_PIG Isoform 1 of Vesicle associated membrane protein 2 OS=Sus scrofa OX=9823 GN=VAMP2 PE=1 SV=2 CANONICAL=A0A5G2R276-1" }, "locus": { "chromosome": "12", "start_pos": 53381813, "end_pos": 53380673, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080340.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080340.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071291.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071291.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY50", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY50" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-181429", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-181429", "resource": "Reactome", "description": "Serotonin Neurotransmitter Release Cycle" }, { "id": "R-SSC-181430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-181430", "resource": "Reactome", "description": "Norepinephrine Neurotransmitter Release Cycle" }, { "id": "R-SSC-199992", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-199992", "resource": "Reactome", "description": "trans-Golgi Network Vesicle Budding" }, { "id": "R-SSC-210500", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-210500", "resource": "Reactome", "description": "Glutamate Neurotransmitter Release Cycle" }, { "id": "R-SSC-212676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212676", "resource": "Reactome", "description": "Dopamine Neurotransmitter Release Cycle" }, { "id": "R-SSC-264642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264642", "resource": "Reactome", "description": "Acetylcholine Neurotransmitter Release Cycle" }, { "id": "R-SSC-432720", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432720", "resource": "Reactome", "description": "Lysosome Vesicle Biogenesis" }, { "id": "R-SSC-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" }, { "id": "R-SSC-449836", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-449836", "resource": "Reactome", "description": "Other interleukin signaling" }, { "id": "R-SSC-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-SSC-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" }, { "id": "R-SSC-888590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-888590", "resource": "Reactome", "description": "GABA synthesis, release, reuptake and degradation" }, { "id": "R-SSC-9609523", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9609523", "resource": "Reactome", "description": "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R276", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R276", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R276", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R276", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R276", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R276", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" } ], "pmid": "" }, { "name": "SNARE complex assembly", "id": "GO:0035493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035493", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R276", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R276", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R276", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" } ], "pmid": "" }, { "name": "syntaxin-1 binding", "id": "GO:0017075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017075", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R276", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R276-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 201, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R276-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R276" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R276" }, { "id": "PS50892", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50892" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "V-SNARE coiled-coil homology", "eco_id": "ECO_0000259", "start_pos": 104, "end_pos": 164, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R533-1", "uniprot_ac": "A0A5G2R533", "uniprot_id": "A0A5G2R533_PIG", "mass": { "chemical_mass": 47299.0, "monoisotopic_mass": 47299.0 }, "refseq": {}, "gene_names": [ { "name": "AP3M2", "type": "recommended", "evidence": [ { "id": "A0A5G2R533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ] } ], "protein_names": [ { "name": "AP-3 complex subunit mu-2", "type": "recommended", "evidence": [ { "id": "A0A5G2R533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AP3M2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533", "locus": { "chromosome": "17", "start_pos": 11190854, "end_pos": 11167161, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007033", "url": "https://www.ensembl.org/id/ENSSSCG00000007033" } ] } } ], "crossref": [ { "id": "A0A5G2R533", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R533", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000007033", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007033", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09261", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09261", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14837", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14837", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100525135", "url": "https://www.ncbi.nlm.nih.gov/gene/100525135", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525135", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525135", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LIWNIGK", "url": "https://omabrowser.org/oma/group/LIWNIGK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8D0SEL7", "url": "https://www.orthodb.org/?gene=A0A8D0SEL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10529", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10529", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00928", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00928", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZZ65", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZ65-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R533-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0SEL7", "url": "https://www.uniprot.org/uniprotkb/A0A8D0SEL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0SEL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0SEL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQTMGKTIEGVTVASQMPRGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSLQAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKNPINIRTVFR", "length": 420, "header": "tr|A0A5G2R533-1|A0A5G2R533_PIG Isoform 1 of AP-3 complex subunit mu-2 OS=Sus scrofa OX=9823 GN=AP3M2 PE=1 SV=1 CANONICAL=A0A5G2R533-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZ65-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533/entry#A0A286ZZ65-1", "sequence": { "sequence": "MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQTMGKTIEGVTVASQMPRGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSLQAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQFEPEGRVLQREQSWTLFHFLLVQK", "length": 393, "header": "tr|A0A286ZZ65-1|A0A5G2R533_PIG Computationally mapped isoform of AP-3 complex subunit mu-2 OS=Sus scrofa OX=9823 GN=AP3M2 PE=1 SV=1 CANONICAL=A0A5G2R533-1" }, "locus": { "chromosome": "17", "start_pos": 11188848, "end_pos": 11168948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045201.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045201.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036788.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036788.1" } ] } }, { "isoform_ac": "A0A5G2R533-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533/entry#A0A5G2R533-1", "sequence": { "sequence": "MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQTMGKTIEGVTVASQMPRGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSLQAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKNPINIRTVFR", "length": 420, "header": "tr|A0A5G2R533-1|A0A5G2R533_PIG Isoform 1 of AP-3 complex subunit mu-2 OS=Sus scrofa OX=9823 GN=AP3M2 PE=1 SV=1 CANONICAL=A0A5G2R533-1" }, "locus": { "chromosome": "17", "start_pos": 11189440, "end_pos": 11168948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073088.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073088.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069285.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069285.1" } ] } }, { "isoform_ac": "A0A8D0SEL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533/entry#A0A8D0SEL7-1", "sequence": { "sequence": "MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQTMGKTIEGVTVASQMPRGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSLQAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQFEPEGRVLQREQSWTLFHFLLVQK", "length": 439, "header": "tr|A0A8D0SEL7-1|A0A5G2R533_PIG Computationally mapped isoform of AP-3 complex subunit mu-2 OS=Sus scrofa OX=9823 GN=AP3M2 PE=1 SV=1 CANONICAL=A0A5G2R533-1" }, "locus": { "chromosome": "17", "start_pos": 11188848, "end_pos": 11168948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007702.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007702.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007495.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007495.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZ65", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ65" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525135", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525135", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NUM5-1", "protein_name": "AP-3 complex subunit mu-2", "gene_name": "AP3M2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIHSLFLINASGDIFLEKHWKSVVSRSVCDYFFEAQERASEAENVPPVISTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEVMIKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNINFRDSSSLGRFEITVGPKQTMGKTVEGVMVTSQMPKGVLNMSLTPSQGTHIFDPVTKLLTWDVGKINPQKLPSLKGSMNLQAGTSKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT", "length": 418 }, "evidence": [ { "id": "A0A5G2R533", "url": "https://omabrowser.org/oma/group/A0A5G2R533/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HHH9-1", "protein_name": "AP-3 complex subunit mu-2", "gene_name": "Ap3m2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVVEEIDAIIDKSGSTVTAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFKRWESERILSFIPPDGSFRLLSYHVSAQNLVAIPVYVKHSISFRDSSSLGRFEITVGPKQTMGKTIEGVIVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSLQVGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT", "length": 418 }, "evidence": [ { "id": "A0A5G2R533", "url": "https://omabrowser.org/oma/group/A0A5G2R533/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P53677-1", "protein_name": "AP-3 complex subunit mu-2", "gene_name": "AP3M2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQTMGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSLQAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT", "length": 418 }, "evidence": [ { "id": "A0A5G2R533", "url": "https://omabrowser.org/oma/group/A0A5G2R533/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P53678-1", "protein_name": "AP-3 complex subunit mu-2", "gene_name": "Ap3m2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIHSLFLINSAGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVVEEIDAIIDKSGSTVTAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHSISFRDSGSLGRFEITVGPKQTMGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMGLQVGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT", "length": 418 }, "evidence": [ { "id": "A0A5G2R533", "url": "https://omabrowser.org/oma/group/A0A5G2R533/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R2R9-1", "protein_name": "AP-3 complex subunit mu-2", "gene_name": "Ap3m2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVVEEIDAIIDKSGSTVTAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFKRWESERILSFIPPDGNFRLLAYHVSAQNLVAIPVYVKHSISFRDSSSLGRFEITVGPKQTMGKTIEGVIVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMGLQVGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT", "length": 418 }, "evidence": [ { "id": "A0A5G2R533", "url": "https://omabrowser.org/oma/group/A0A5G2R533/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "clathrin adaptor complex", "id": "GO:0030131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030131", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "anterograde synaptic vesicle transport", "id": "GO:0048490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048490", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R533-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 420, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R533-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R533" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R533" }, { "id": "PS51072", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51072" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MHD", "eco_id": "ECO_0000259", "start_pos": 176, "end_pos": 418, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 279, "end_pos": 281 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYC9-1", "uniprot_ac": "A0A5G2QYC9", "uniprot_id": "A0A5G2QYC9_PIG", "mass": { "chemical_mass": 100305.0, "monoisotopic_mass": 100305.0 }, "refseq": {}, "gene_names": [ { "name": "PIGN", "type": "recommended", "evidence": [ { "id": "A0A5G2QYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9" } ] } ], "protein_names": [ { "name": "GPI ethanolamine phosphate transferase 1", "type": "recommended", "evidence": [ { "id": "A0A5G2QYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9/entry#names_and_taxonomy" } ] }, { "name": "2.-.-.-", "type": "synonym", "evidence": [ { "id": "A0A5G2QYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0N3", "url": "https://www.uniprot.org/uniprotkb/A0A287A0N3#function" }, { "database": "UniProtKB", "id": "RU367138", "url": "https://www.uniprot.org/uniprotkb/RU367138#function" }, { "database": "UniProtKB", "id": "A0A5G2QYC9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYC9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PIGN", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9", "locus": { "chromosome": "1", "start_pos": 159417327, "end_pos": 159317734, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004901", "url": "https://www.ensembl.org/id/ENSSSCG00000004901" } ] } } ], "crossref": [ { "id": "A0A5G2QYC9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004901", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004901", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16020", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16020", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522054", "url": "https://www.ncbi.nlm.nih.gov/gene/100522054", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12250", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12250", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12250:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12250:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01663", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01663", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04987", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04987", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-162710", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-162710", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A0N3", "url": "https://www.uniprot.org/uniprotkb/A0A287A0N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A0N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0N3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYC9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLYIIFGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADKLYELDENGNSRAPFIRDIIMHKGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDFLFNETNYSWSWGSPDLLVMFSKGAKRNNVFPCSYDASSEDFGAQDVTKLDTWVFDNVKELFRGARNNQSLFSKLNEDKIVFFLHLLGIDTNGHAHRPSSRAGHPSETNTPFVTWGAGIKYPQRVSAQKFDDTYLEEWKLENWKRHDVNQADIAPLMASLIGVPFPLNSVGILPVDILNTTDLFKAESMFTNAVQILEQFKVKMTQKKEATLSFLFTPFKSLSDSKQINILRKARSYIKQKKYDEAVSLCKELINLALKGLSYYHTYDRFFLGFNVVLGFVGWTSYASLLIIKSHCNLTIGVSKEVKKPSHLLLCSFVALGLLVALFLLLQACPWTYYVYCLLPLPIWYAVLREFPVIQDFVTLLLTNPPNHFVGYLLLFILGVEVLVVSFFYRYMLTAGLIAFAGWPFITPLWTRAKSTSLSWIFFCLLLAVFPLMPVVGRKPDIFLVMGAGLLVLLLSLLVLTFVIRRKNGFVNEELVLYLLQMLSVVVSICVVYGTHNSLLKKQGLPLTNQIASWIILASSLVIPLLSSPILFDRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIYMEQETLQQSGISCKQKLSTIQFACNTDLTQFRDFSLDDIRRAFFLVFFLVTAFFGTGNIASVNSFDLASVYCFLTVFSPYMMGALMIWKILIPFVFVMCAFEAVQLTTQLSSKSLFLMVIIISDVMALHFFFLIKDFGSWLDIGTSISHYVIVMSMTIFLMFLNGLAQILTTKKLKLWGRPKSHLI", "length": 884, "header": "tr|A0A5G2QYC9-1|A0A5G2QYC9_PIG Isoform 1 of GPI ethanolamine phosphate transferase 1 OS=Sus scrofa OX=9823 GN=PIGN PE=3 SV=2 CANONICAL=A0A5G2QYC9-1" }, "isoforms": [ { "isoform_ac": "A0A287A0N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9/entry#A0A287A0N3-1", "sequence": { "sequence": "MEILGHHLLGWKENPVEFDFLFNETNYSWSWGSPDLLVMFSKGAKRNNVFPCSYDASSEDFGAQDVTKLDTWVFDNVKELFRGARNNQSLFSKLNEDKIVFFLHLLGIDTNGHAHRPSSRDYLDNIKIVDDGLKEIESTLKDFYGNDEKTAFIFTSDHGMTDWGSHGAGHPSETNTPFVTWGAGIKYPQRVSAQKFDDTYLEEWKLENWKRHDVNQADIAPLMASLIGVPFPLNSVGILPVDILNTTDLFKAESMFTNAVQILEQFKVKMTQKKEATLSFLFTPFKSLSDSKQINILRKARSYIKQKKYDEAVSLCKELINLALKGLSYYHTYDRFFLGFNVVLGFVGWTSYASLLIIKSHCNLTIGVSKEVKKPSHLLLCSFVALGLLVALFLLLQACPWTYYVYCLLPLPIWYAVLREFPVIQDFVTLLLTNPPNHFVGYLLLFILGVEVLVVSFFYRYMLTAGLIAFAGWPFITPLWTRAKSTSLSWIFFCLLLAVFPLMPVVGRKPDIFLVMGAGLLVLLLSLLVLTFVIRRKNGFVNEELVLYLLQMLSVVVSICVVYGTHNSLLKKQGLPLTNQIASWIILASSLVIPLLSSPILFDRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIYMEQETLQQSGISCKQKLSTIQFACNTDLTQFRDFSLDDIRRAFFLVFFLVTAFFGTGNIASVNSFDLASVYCFLTVFSPYMMGALMIWKILIPFVFVMCAFEAVQLTTQLSSKSLFLMVIIISDVMALHFFFLIKDFGSWLDIGTSISHYVIVMSMTIFLMFLNGLAQILTTKKLKLWGRPKSHLI", "length": 826, "header": "tr|A0A287A0N3-1|A0A5G2QYC9_PIG Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Sus scrofa OX=9823 GN=PIGN PE=3 SV=1 CANONICAL=A0A5G2QYC9-1" }, "locus": { "chromosome": "1", "start_pos": 159415172, "end_pos": 159326140, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039986.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039986.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037468.1", "url": "https://www.ensembl.org/id/ENSSSCP00000037468.1" } ] } }, { "isoform_ac": "A0A5G2QYC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9/entry#A0A5G2QYC9-1", "sequence": { "sequence": "MLLYIIFGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADKLYELDENGNSRAPFIRDIIMHKGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDFLFNETNYSWSWGSPDLLVMFSKGAKRNNVFPCSYDASSEDFGAQDVTKLDTWVFDNVKELFRGARNNQSLFSKLNEDKIVFFLHLLGIDTNGHAHRPSSRAGHPSETNTPFVTWGAGIKYPQRVSAQKFDDTYLEEWKLENWKRHDVNQADIAPLMASLIGVPFPLNSVGILPVDILNTTDLFKAESMFTNAVQILEQFKVKMTQKKEATLSFLFTPFKSLSDSKQINILRKARSYIKQKKYDEAVSLCKELINLALKGLSYYHTYDRFFLGFNVVLGFVGWTSYASLLIIKSHCNLTIGVSKEVKKPSHLLLCSFVALGLLVALFLLLQACPWTYYVYCLLPLPIWYAVLREFPVIQDFVTLLLTNPPNHFVGYLLLFILGVEVLVVSFFYRYMLTAGLIAFAGWPFITPLWTRAKSTSLSWIFFCLLLAVFPLMPVVGRKPDIFLVMGAGLLVLLLSLLVLTFVIRRKNGFVNEELVLYLLQMLSVVVSICVVYGTHNSLLKKQGLPLTNQIASWIILASSLVIPLLSSPILFDRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIYMEQETLQQSGISCKQKLSTIQFACNTDLTQFRDFSLDDIRRAFFLVFFLVTAFFGTGNIASVNSFDLASVYCFLTVFSPYMMGALMIWKILIPFVFVMCAFEAVQLTTQLSSKSLFLMVIIISDVMALHFFFLIKDFGSWLDIGTSISHYVIVMSMTIFLMFLNGLAQILTTKKLKLWGRPKSHLI", "length": 884, "header": "tr|A0A5G2QYC9-1|A0A5G2QYC9_PIG Isoform 1 of GPI ethanolamine phosphate transferase 1 OS=Sus scrofa OX=9823 GN=PIGN PE=3 SV=2 CANONICAL=A0A5G2QYC9-1" }, "locus": { "chromosome": "1", "start_pos": 159415172, "end_pos": 159325947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074435.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074435.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066951.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066951.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0N3", "url": "https://www.uniprot.org/uniprotkb/A0A287A0N3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-162710", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-162710", "resource": "Reactome", "description": "Synthesis of glycosylphosphatidylinositol (GPI)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mannose-ethanolamine phosphotransferase activity", "id": "GO:0051377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051377", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYC9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYC9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYC9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYC9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYC9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-162798", "name": "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-8855659" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-162798", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-162798" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8855659", "participant_name": "mannose (a1-4) glucosaminyl-acyl-PI [lumenal side of endoplasmic reticulum membrane]", "crossref": [ { "id": "53056", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QYC9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 884, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QYC9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYC9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC9" }, { "id": "PF04987", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04987" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GPI ethanolamine phosphate transferase 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 383, "end_pos": 837, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 131, "end_pos": 133 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 421, "end_pos": 423 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZI1-1", "uniprot_ac": "A0A5G2QZI1", "uniprot_id": "A0A5G2QZI1_PIG", "mass": { "chemical_mass": 90700.0, "monoisotopic_mass": 90700.0 }, "refseq": { "ac": "XP_020942923", "name": "metal transporter CNNM3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942923" }, "gene_names": [ { "name": "CNNM3", "type": "recommended", "evidence": [ { "id": "A0A5G2QZI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1" } ] }, { "name": "CNNM3", "type": "synonym", "evidence": [ { "id": "XP_020942923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942923" } ] } ], "protein_names": [ { "name": "Metal transporter", "type": "recommended", "evidence": [ { "id": "A0A5G2QZI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1/entry#names_and_taxonomy" } ] }, { "name": "metal transporter CNNM3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020942923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942923" } ] } ], "function": [ { "annotation": "Metal transporter.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4N8", "url": "https://www.uniprot.org/uniprotkb/A0A287A4N8#function" }, { "database": "UniProtKB", "id": "RU369091", "url": "https://www.uniprot.org/uniprotkb/RU369091#function" }, { "database": "UniProtKB", "id": "A0A287BA80", "url": "https://www.uniprot.org/uniprotkb/A0A287BA80#function" }, { "database": "UniProtKB", "id": "A0A5G2R2P5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P5#function" }, { "database": "UniProtKB", "id": "A0A5G2QZI1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1#function" }, { "database": "UniProtKB", "id": "F1STC7", "url": "https://www.uniprot.org/uniprotkb/F1STC7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZI1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CNNM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1", "locus": { "chromosome": "3", "start_pos": 56792391, "end_pos": 56811789, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008201", "url": "https://www.ensembl.org/id/ENSSSCG00000008201" } ] } } ], "crossref": [ { "id": "A0A5G2QZI1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZI1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008201", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008201", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04590", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04590", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512161", "url": "https://www.ncbi.nlm.nih.gov/gene/100512161", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512161", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512161", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KLMFMHA", "url": "https://omabrowser.org/oma/group/KLMFMHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QZI1", "url": "https://www.orthodb.org/?gene=A0A5G2QZI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12064:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12064:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020942923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942923", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A4N8", "url": "https://www.uniprot.org/uniprotkb/A0A287A4N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4N8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BA80", "url": "https://www.uniprot.org/uniprotkb/A0A287BA80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BA80-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BA80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZI1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2P5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STC7", "url": "https://www.uniprot.org/uniprotkb/F1STC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STC7-1", "url": "https://www.uniprot.org/uniprotkb/F1STC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAATAGRLGWLLAAFCLGNAAAEAAPGPRVLGVCLEEDGAAGTGWARGEEVRTAPEATFRLRLFGSGLANSSWSWVAPEGAGCPEGGPVAAPDEAAAPTGEWRALLRLRAEAAHPHSARLAVRGEPGGAAAPTGEWRALLRLRSESAHPHSALLAVRVEPGGEAAEEAAPPWAVGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPSRRWAGCALGALLLLASLAQAALAVLLYRAAGQRAVPAVLGSAGLLFLVGEVVPAAVSGRWTLALAPRALILSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDPYSDLSKGVLPCRTVEDVLTPLEDCFMLDASTVLDFGVLASIMQSGHTRIPVYEEERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESEDYRDTIVKKKPASLSAPLRQKEEFSLFKVSDDEYKVKISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVRFDESNRLAAHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALAAPSSGKLQPPWCWGLGWQSQWPRPLAGRSALQPAGPSWLRAAWREGQPFFRAHLCCPSHPCRTSPGRACLFSSESPSDGGWPLEAVLLSPGQGWPAPPPTVLPVVPQSPVSSLQSVRHDLPPEPADGTRLSAYCPDYTVRALSDLQFIKVTRLQYLNALLATRAQALPQPSENADLQTIPGSQTRLLGDKAATAAGSNHSRPGLPVEESPGRNPGV", "length": 845, "header": "tr|A0A5G2QZI1-1|A0A5G2QZI1_PIG Isoform 1 of Metal transporter OS=Sus scrofa OX=9823 GN=CNNM3 PE=1 SV=1 CANONICAL=A0A5G2QZI1-1" }, "isoforms": [ { "isoform_ac": "A0A287A4N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1/entry#A0A287A4N8-1", "sequence": { "sequence": "MAAATAGRLGWLLAAFCLGNAAAEAAPGPRVLGVCLEEDGAAGTGWARGEEVRTAPEATFRLRLFGSGLANSSWSWVAPEGAGCPEGGPVAAPDEAAAPTGEWRALLRLRAEAAHPHSARLAVRGEPGGAAAPTGEWRALLRLRSESAHPHSALLAVRVEPGGEAAEEAAPPWAVGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPSRRWAGCALGALLLLASLAQAALAVLLYRAAGQRAVPAVLGSAGLLFLVGEVVPAAVSGRWTLALAPRALILSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDPYSDLSKGVLPCRTVEDVLTPLEDCFMLDASTVLDFGVLASIMQSGHTRIPVYEEERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESEDYRDTIVKKKPASLSAPLRQKEEFSLFKVSDDEYKVKISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVRFDESNRLAAHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALAAPSSVPQSPVSSLQSVRHDLPPEPADGTRLSAYCPDYTVRALSDLQFIKVTRLQYLNALLATRAQALPQPSENADLQTIPGSQTRLLGDKAATAAGEPHGVTPG", "length": 733, "header": "tr|A0A287A4N8-1|A0A5G2QZI1_PIG Computationally mapped isoform of Metal transporter OS=Sus scrofa OX=9823 GN=CNNM3 PE=1 SV=2 CANONICAL=A0A5G2QZI1-1" }, "locus": { "chromosome": "3", "start_pos": 56811744, "end_pos": 56797984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063118.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063118.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038744.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038744.2" } ] } }, { "isoform_ac": "A0A287BA80-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1/entry#A0A287BA80-1", "sequence": { "sequence": "MAAATAGRLGWLLAAFCLGNAAAEAAPGPRVLGVCLEEDGAAGTGWARGEEVRTAPEATFRLRLFGSGLANSSWSWVAPEGAGCPEGGPVAAPDEAAAPTGEWRALLRLRAEAAHPHSARLAVRGEPGGAAAPTGEWRALLRLRSESAHPHSALLAVRVEPGGEAAEEAAPPWAVGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPSRRWAGCALGALLLLASLAQAALAVLLYRAAGQRAVPAVLGSAGLLFLVGEVVPAAVSGRWTLALAPRALILSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDPYSDLSKGVLPCRTVEDVLTPLEDCFMLDASTVLDFGVLASIMQSGHTRIPVYEEERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESEDYRDTIVKKKPASLSAPLRQKEEFSLFKVSDDEYKVKISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVRFDESNRLAAHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALAAPSSVPQSPVSSLQSVRHDLPPEPADGTRLSAYCPDYTVRALSDLQFIKVTRLQYLNALLATRAQALPQPSENADLQTIPGSQTRLLGDKAATAAGLGHLESEDLDHH", "length": 737, "header": "tr|A0A287BA80-1|A0A5G2QZI1_PIG Computationally mapped isoform of Metal transporter OS=Sus scrofa OX=9823 GN=CNNM3 PE=1 SV=1 CANONICAL=A0A5G2QZI1-1" }, "locus": { "chromosome": "3", "start_pos": 56811744, "end_pos": 56797523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065321.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065321.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053412.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053412.1" } ] } }, { "isoform_ac": "A0A5G2QZI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1/entry#A0A5G2QZI1-1", "sequence": { "sequence": "MAAATAGRLGWLLAAFCLGNAAAEAAPGPRVLGVCLEEDGAAGTGWARGEEVRTAPEATFRLRLFGSGLANSSWSWVAPEGAGCPEGGPVAAPDEAAAPTGEWRALLRLRAEAAHPHSARLAVRGEPGGAAAPTGEWRALLRLRSESAHPHSALLAVRVEPGGEAAEEAAPPWAVGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPSRRWAGCALGALLLLASLAQAALAVLLYRAAGQRAVPAVLGSAGLLFLVGEVVPAAVSGRWTLALAPRALILSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDPYSDLSKGVLPCRTVEDVLTPLEDCFMLDASTVLDFGVLASIMQSGHTRIPVYEEERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESEDYRDTIVKKKPASLSAPLRQKEEFSLFKVSDDEYKVKISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVRFDESNRLAAHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALAAPSSGKLQPPWCWGLGWQSQWPRPLAGRSALQPAGPSWLRAAWREGQPFFRAHLCCPSHPCRTSPGRACLFSSESPSDGGWPLEAVLLSPGQGWPAPPPTVLPVVPQSPVSSLQSVRHDLPPEPADGTRLSAYCPDYTVRALSDLQFIKVTRLQYLNALLATRAQALPQPSENADLQTIPGSQTRLLGDKAATAAGSNHSRPGLPVEESPGRNPGV", "length": 845, "header": "tr|A0A5G2QZI1-1|A0A5G2QZI1_PIG Isoform 1 of Metal transporter OS=Sus scrofa OX=9823 GN=CNNM3 PE=1 SV=1 CANONICAL=A0A5G2QZI1-1" }, "locus": { "chromosome": "3", "start_pos": 56811744, "end_pos": 56794585, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082804.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082804.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069543.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069543.1" } ] } }, { "isoform_ac": "A0A5G2R2P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1/entry#A0A5G2R2P5-1", "sequence": { "sequence": "MAAATAGRLGWLLAAFCLGNAAAEAAPGPRVLGVCLEEDGAAGTGWARGEEVRTAPEATFRLRLFGSGLANSSWSWVAPEGAGCPEGGPVAAPDEAAAPTGEWRALLRLRAEAAHPHSARLAVRGEPGGAAAPTGEWRALLRLRSESAHPHSALLAVRVEPGGEAAEEAAPPWAVGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPSRRWAGCALGALLLLASLAQAALAVLLYRAAGQRAVPAVLGSAGLLFLVGEVVPAAVSGRWTLALAPRALILSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDPYSDLSKGVLPCRTVEDVLTPLEDCFMLDASTVLDFGVLASIMQSGHTRIPVYEEERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESEDYRDTIVKKKPASLSAPLRQKEEFSLFKVSDDEYKVKISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVRFDESNRLAAHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALAAPSSGKLQPPWCWGLGWQSQWPRPLAGRSALQPAGPSWLRAAWREGQPFFRAHLCCPSHPCRTSPGRACLFSSESPSDGGWPLEAVLLSPGQGWPAPPPTVLPVVPQSPVSSLQSVRHDLPPEPADGTRLSAYCPDYTVRALSDLQFIKVTRLQYLNALLATRAQALPQPSENADLQTIPGSQTRLLGDKAATAAGEPHGVTPG", "length": 833, "header": "tr|A0A5G2R2P5-1|A0A5G2R2P5_PIG Computationally mapped isoform of Metal transporter OS=Sus scrofa OX=9823 GN=CNNM3 PE=1 SV=1 CANONICAL=A0A5G2QZI1-1" }, "locus": { "chromosome": "3", "start_pos": 56811744, "end_pos": 56797984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077580.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077580.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070611.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070611.1" } ] } }, { "isoform_ac": "F1STC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1/entry#F1STC7-1", "sequence": { "sequence": "MAAATAGRLGWLLAAFCLGNAAAEAAPGPRVLGVCLEEDGAAGTGWARGEEVRTAPEATFRLRLFGSGLANSSWSWVAPEGAGCPEGGPVAAPDEAAAPTGEWRALLRLRAEAAHPHSARLAVRGEPGGAAAPTGEWRALLRLRSESAHPHSALLAVRVEPGGEAAEEAAPPWAVGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPSRRWAGCALGALLLLASLAQAALAVLLYRAAGQRAVPAVLGSAGLLFLVGEVVPAAVSGRWTLALAPRALILSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDPYSDLSKGVLPCRTVEDVLTPLEDCFMLDASTVLDFGVLASIMQSGHTRIPVYEEERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESEDYRDTIVKKKPASLSAPLRQKEEFSLFKVSDDEYKVKISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVRFDESNRLAAHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALAAPSSVPQSPVSSLQSVRHDLPPEPADGTRLSAYCPDYTVRALSDLQFIKVTRLQYLNALLATRAQALPQPSENADLQTIPGSQTRLLGDKAATAAAFPVDLSLLGTFGNCN", "length": 740, "header": "tr|F1STC7-1|F1STC7_PIG Computationally mapped isoform of Metal transporter OS=Sus scrofa OX=9823 GN=CNNM3 PE=1 SV=4 CANONICAL=A0A5G2QZI1-1" }, "locus": { "chromosome": "3", "start_pos": 56811744, "end_pos": 56795157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008982.5", "url": "https://www.ensembl.org/id/ENSSSCT00000008982.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008756.4", "url": "https://www.ensembl.org/id/ENSSSCP00000008756.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4N8", "url": "https://www.uniprot.org/uniprotkb/A0A287A4N8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512161", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512161", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACK7-1", "protein_name": "Metal transporter", "gene_name": "Cnnm3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAAAVAGWLGWVLAAFCLGSTAGEAAPGAGLLSFCTEEDGAPGAGSLRGRAAPEATLCLRLFCPGLANSSWTWVAPEGAGCPEGGRATEPSEAAAPTGEWRALLRLRAEAGHPRSALLAVRVEPGGGAAEEAAAPWALGLGAAGLLALAAVARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPARRWAGCALGALLLLASLAQAALAVLLYGAVGQRAVPAVLGCAGLVFLVGEVLPAAVSGRWALALAPRALGLSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDPYSDLSKGVLRYRTVEDVLTPLEDCFMLDSGTVLDFSVLASIMQSGHTRIPVFEEERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIRSEILDESEDYSDTKVKKKAVTLGAPLKRKEEFSLFKVSDDEYKVKISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVKFDESNRLATHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALTAPSSAHQSPVSSRQLIRHDLQPEPADSTRSCTYCPDYTVRALSDLQLIKVTRLQYLNALLATRAQSLPPSPENAELQAIPGSQTRLLGDKSRETAGPSSSRRSIPVEESPGRNPGV", "length": 711 }, "evidence": [ { "id": "A0A5G2QZI1", "url": "https://omabrowser.org/oma/group/A0A5G2QZI1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N293-1", "protein_name": "Metal transporter", "gene_name": "CNNM3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAAAAAGRLGWLLAALCLGNAAGEAAPDPRVLGVCLEEDGAAGAGWAHEGEVRAAPEATFRLRLFGSGFSNSSWSWVAPEGAGCPEGGPAAAPDEAAAPTGEWRALLRLRAEAARPHSVRLAVRGEPGGSAAEEAAALTGEWRALLRLRAEAARPHSALLAVRVEPGGSAAEEEAPPWALGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPARRWAGCALGALLLLASLAQAALAVLLYRAAGQRAVPAVLGSAGLVFLVGEVVPAAVSGRWTLALAPRALILSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDPYSDLSKGVLPCRTVEDVLTPLEDCFMLDASTVLDFGVLASIMQSGHTRIPVYEDERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESEDYRDTIVKKKPASLNAPLRQKEEFSLFKVSDDDCKVKISPQLLLATQRFLSREVDVFSPLRVSEKVLLHLLKHPSVNQEVRFDESNRLASHHYLYQRSRPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALTAPSSVHQSPVSSLQSLRYDPPPEPTDGTCLSAYCPDYTVRALSDLQFIKVTRLQYLNALLATRAQALPQTPENTELLAIPGSQTRLLGDKAATAPDSVSYGLCSALVFTIGKKPTSHPTLQWGHRDLPEGCLCLALF", "length": 773 }, "evidence": [ { "id": "A0A5G2QZI1", "url": "https://omabrowser.org/oma/group/A0A5G2QZI1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q32NY4-1", "protein_name": "Metal transporter CNNM3", "gene_name": "Cnnm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAAAVVGWLGWVLAAFCLGSTAGEAAPAPGAGLLNFCTEEDSAPGAGSLRGRAAPEATLCLRLFCSGLANSSWTWVAAEGAGCPEGGRATEPEEAAAPTGEWRALLRLRAEAGHPRSALLAVRVEPGGGAAEEAAPPWALGLGAAGLLALAAVARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPARRWAGCALGALLLLASLAQAALAVLLYGAAGQRAVPAVLGCAGLVFLVGEVLPAAVSGRWALALAPRALGLSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDPYSDLSKGVLRSRTVEDVLTPLEDCFMLDSGTVLDFSVLASIMQSGHTRIPVYEEERSNIVDMLYLKDLAIVEPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESEDYSDTKVRKKTVALGAPLKRKEEFSLFKVSDDEYKVKISPQLLLATQRFLSREVDVFSPLRVSEKVLLHLLKHPSVNQEVTFDESNRLAAHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALTAPSSAHQSPVSSRQLIRHDVQPEPADGTRSCTYCPDYTVRALSDLQLIKVTRLQYLNALLATRAQSLPPSPENAELQAIPGSQTRLLGDKSRETAGSTNSRPSIPVEESPGRNPGV", "length": 713 }, "evidence": [ { "id": "A0A5G2QZI1", "url": "https://omabrowser.org/oma/group/A0A5G2QZI1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54W99-1", "protein_name": "CNNM transmembrane domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTSVQYYFFQWISIIVLVAISGLFAGLTLGIMSLDITGLEIIIASGTAKESKYAKIIYPVRQKGNLLLCTLLLGNVGVNALLSIFLADLTSGFVGFILSTTIIVIAGEIIPQAACSRHGLAVGAHTIYIVYVFIFLFFPFAYPISLTLDWILGNEMGTIYSRNQLKKLLDIHSAHANESGVSRSDVTMLTGVLDFAHKKVSLIMTPMERVFSVDIESLLDYNTITLILESGHSRIPVFEGNKSNIVGCLYVKDLALLNPADKVPLRTILNLYKRQLVKTWNDTSLDQMLTEFKTGRSHMAIVHKVNNEGEGDPFYENLGIICLEDIIEEILQDEILDENDMYHEVRKKNQHHSTFDYRTIGSFHGPKTALAQLSSQQVKAIYSYLSGSIDEFSSKFISENVFIKMLSTKGAIVLDVDRPATGDKFIYTRGVATDFFTIILQGKVEIRSGSEAFISEGGPFSTLGVGALKSDHFVPDFTARVISGNISYLKIPKSVYDQSVISTDDEYNTKIFNRNRVDLSGSSSSANVNTSSSSGHSRSISNDDRPTSSPIINNVSSSPNIPSSILTNNNNNNNNSTNTTTTTTTTTTSTKNKENESDNSESEDDSDDNYNSQKPILSTPKNNFLQNIRKSDTNI", "length": 635 }, "evidence": [ { "id": "A0A5G2QZI1", "url": "https://omabrowser.org/oma/group/A0A5G2QZI1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NE01-1", "protein_name": "Metal transporter CNNM3", "gene_name": "CNNM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAVAAAGRLGWLFAALCLGNAAGEAAPGPRVLGFCLEEDGAAGAGWVRGGAARDTPDATFLLRLFGPGFANSSWSWVAPEGAGCREEAASPAGEWRALLRLRLRAEAVRPHSALLAVRVEPGGGAAEEAAPPWALGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPARRWAGCALGALLLLASLAQAALAVLLYRAAGQRAVPAVLGSAGLVFLVGEVVPAAVSGRWTLALAPRALGLSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDPYSDLSKGVLRCRTVEDVLTPLEDCFMLDASTVLDFGVLASIMQSGHTRIPVYEEERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIRSEILDESEDYRDTVVKRKPASLMAPLKRKEEFSLFKVSDDEYKVTISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVRFDESNRLATHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALTVPSSVHQSPVSSLQPIRHDLQPDPGDGTHSSAYCPDYTVRALSDLQLIKVTRLQYLNALLATRAQNLPQSPENTDLQVIPGSQTRLLGEKTTTAAGSSHSRPGVPVEGSPGRNPGV", "length": 707 }, "evidence": [ { "id": "A0A5G2QZI1", "url": "https://omabrowser.org/oma/group/A0A5G2QZI1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZI1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZI1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1" } ], "pmid": "" }, { "name": "magnesium ion homeostasis", "id": "GO:0010960", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010960", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZI1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZI1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZI1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 845, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZI1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZI1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1" }, { "id": "PS51371", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51371" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBS", "eco_id": "ECO_0000259", "start_pos": 424, "end_pos": 490, "start_aa": "Tyr", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QZI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI1" }, { "id": "PS51846", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51846" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CNNM transmembrane", "eco_id": "ECO_0000259", "start_pos": 168, "end_pos": 346, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 433, "end_pos": 435 }, { "start_pos": 71, "end_pos": 73 }, { "start_pos": 827, "end_pos": 829 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWR0-1", "uniprot_ac": "A0A5G2QWR0", "uniprot_id": "A0A5G2QWR0_PIG", "mass": { "chemical_mass": 49767.0, "monoisotopic_mass": 49767.0 }, "refseq": {}, "gene_names": [ { "name": "CYP11B2", "type": "recommended", "evidence": [ { "id": "A0A5G2QWR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ] } ], "protein_names": [ { "name": "Cytochrome P450 family 11 subfamily B member 2", "type": "synonym", "evidence": [ { "id": "A0A5G2QWR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CYP11B2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0", "locus": {} } ], "crossref": [ { "id": "A0A5G2QWR0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000031563", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031563", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RMGINSW", "url": "https://omabrowser.org/oma/group/RMGINSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "W0FJN1", "url": "https://www.orthodb.org/?gene=W0FJN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24279", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24279", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24279:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24279:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-193993", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193993", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-194002", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-194002", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-211976", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-211976", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "15629", "url": "https://www.rhea-db.org/rhea/15629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46104", "url": "https://www.rhea-db.org/rhea/46104", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "W0FJN1", "url": "https://www.uniprot.org/uniprotkb/W0FJN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "W0FJN1-1", "url": "https://www.uniprot.org/uniprotkb/W0FJN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAIWAKAEAWLAGPWLALHRARTLGTRAALAPKAVLPFEAIPQCPGNKWMRVLQLWREQGFENIHLDMHQTFQELGPIFRFDVGGRHMVLVMLPEDVERLQKVEGLHPQRMFLEPWLAYRQLRGHKCGVFLLNGPTWRLDRLQLNPGVLSLQAMQKFTPLVDGVARDFSQALRARVMQNARGSLTLDIKPSIFRYTIEASNLVLFGERLGLLAHQPNPESLDFIHALEVMFKSTVQLMFMPRSLSRWTSTGTWKEHFEAWDCIFQYANKAIQRLYQELTLGHPWHYSGVVAELLTHANMTVDAIKANSIDLTAGSVDTTAYPLLMTLFELARNPEVQQALRQESLAAAARISENPQKAITELPLLRAALKETLRLYPVGIFLDRCVSSDLVLQNYHIPAGVLKNFLVETLVQEDIKMIYRFILTPSTLPLLTFRAIS", "length": 437, "header": "tr|A0A5G2QWR0-1|A0A5G2QWR0_PIG Isoform 1 of Cytochrome P450 family 11 subfamily B member 2 OS=Sus scrofa OX=9823 GN=CYP11B2 PE=3 SV=1 CANONICAL=A0A5G2QWR0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0/entry#A0A5G2QWR0-1", "sequence": { "sequence": "MAIWAKAEAWLAGPWLALHRARTLGTRAALAPKAVLPFEAIPQCPGNKWMRVLQLWREQGFENIHLDMHQTFQELGPIFRFDVGGRHMVLVMLPEDVERLQKVEGLHPQRMFLEPWLAYRQLRGHKCGVFLLNGPTWRLDRLQLNPGVLSLQAMQKFTPLVDGVARDFSQALRARVMQNARGSLTLDIKPSIFRYTIEASNLVLFGERLGLLAHQPNPESLDFIHALEVMFKSTVQLMFMPRSLSRWTSTGTWKEHFEAWDCIFQYANKAIQRLYQELTLGHPWHYSGVVAELLTHANMTVDAIKANSIDLTAGSVDTTAYPLLMTLFELARNPEVQQALRQESLAAAARISENPQKAITELPLLRAALKETLRLYPVGIFLDRCVSSDLVLQNYHIPAGVLKNFLVETLVQEDIKMIYRFILTPSTLPLLTFRAIS", "length": 437, "header": "tr|A0A5G2QWR0-1|A0A5G2QWR0_PIG Isoform 1 of Cytochrome P450 family 11 subfamily B member 2 OS=Sus scrofa OX=9823 GN=CYP11B2 PE=3 SV=1 CANONICAL=A0A5G2QWR0-1" }, "locus": { "chromosome": "4", "start_pos": 1373136, "end_pos": 1367924, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084934.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084934.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069384.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069384.1" } ] } }, { "isoform_ac": "W0FJN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0/entry#W0FJN1-1", "sequence": { "sequence": "MAIWAKAEAWLAGPWLALHRARTLGTRAALAPKAVLPFEAIPQCPGNKWMRVLQLWREQGFENIHLDMHQTFQELGPIFRFDVGGRHMVLVMLPEDVERLQKVEGLHPQRMFLEPWLAYRQLRGHKCGVFLLNGPTWRLDRLQLNPGVLSLQAMQKFTPLVDGVARDFSQALRARVMQNARGSLTLDIKPSIFRYTIEASNLVLFGERLGLLAHQPNPESLDFIHALEVMFKSTVQLMFMPRSLSRWTSTGTWKEHFEAWDCIFQYANKAIQRLYQELTLGHPWHYSGVVAELLTHANMTVDAIKANSIDLTAGSVDTTAYPLLMTLFELARNPEVQQALRQESLAAAARISENPQKAITELPLLRAALKETLRLYPVGIFLDRCVSSDLVLQNYHIPAGTLVKVLLYSLGRNPAVFARPERYHPQRWLDNQGSGTRFPHLAFGFGMRQCLGRRLAQVEMLLLLHHVLKNFLVETLVQEDIKMIYRFILTPSTLPLLTFRAIS", "length": 503, "header": "tr|W0FJN1-1|A0A5G2QWR0_PIG Computationally mapped isoform of Cytochrome P450 family 11 subfamily B member 2 OS=Sus scrofa OX=9823 GN=CYP11B2 PE=3 SV=1 CANONICAL=A0A5G2QWR0-1" }, "locus": { "chromosome": "4", "start_pos": 1373136, "end_pos": 1367924, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049306.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049306.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043770.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043770.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "W0FJN1", "url": "https://www.uniprot.org/uniprotkb/W0FJN1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-193993", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193993", "resource": "Reactome", "description": "Mineralocorticoid biosynthesis" }, { "id": "R-SSC-194002", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-194002", "resource": "Reactome", "description": "Glucocorticoid biosynthesis" }, { "id": "R-SSC-211976", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-211976", "resource": "Reactome", "description": "Endogenous sterols" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MWH3-1", "protein_name": "steroid 11beta-monooxygenase", "gene_name": "CYP11B1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALWAKARVRMAGPWLSLHEARLLGTRGAAAPKAVLPFEAMPRCPGNKWMRMLQIWKEQGSENMHLDMHQTFQELGPIFRYDVGGRHMVFVMLPEDVERLQQADSHHPQRMILEPWLAYRQARGHKCGVFLLNGPQWRLDRLRLNPDVLSLPALQKYTPLVDGVARDFSQTLKARVLQNARGSLTLDIAPSVFRYTIEASTLVLYGERLGLLTQQPNPDSLNFIHALEAMLKSTVQLMFVPRRLSRWMSTNMWREHFEAWDYIFQYANRAIQRIYQELALGHPWHYSGIVAELLMRADMTLDTIKANTIDLTAGSVDTTAFPLLMTLFELARNPEVQQAVRQESLVAEARISENPQRAITELPLLRAALKETLRLYPVGITLEREVSSDLVLQNYHIPAGTLVKVLLYSLGRNPAVFARPESYHPQRWLDRQGSGSRFPHLAFGFGVRQCLGRRVAEVEMLLLLHHVLKNFLVETLEQEDIKMVYRFILMPSTLPLFTFRAIQ", "length": 503 }, "evidence": [ { "id": "A0A5G2QWR0", "url": "https://omabrowser.org/oma/group/A0A5G2QWR0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P15538-1", "protein_name": "Cytochrome P450 11B1, mitochondrial", "gene_name": "CYP11B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALRAKAEVCMAVPWLSLQRAQALGTRAARVPRTVLPFEAMPRRPGNRWLRLLQIWREQGYEDLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMFPLLTFRAIN", "length": 503 }, "evidence": [ { "id": "A0A5G2QWR0", "url": "https://omabrowser.org/oma/group/A0A5G2QWR0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15539-1", "protein_name": "Cytochrome P450 11B2, mitochondrial", "gene_name": "Cyp11b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALRVTADVWLARPWQCLHRTRALGTTATLAPKTLQPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQVFRELGPIFRHSVGKTQIVSVMLPEDAEKLHQVESMLPRRMHLEPWVAHRELRGLRRGVFLLNGPEWRLNRLRLNRNVLSPKAVQKFVPMVDMVARDFLETLKEKVLQNARGSLTMDVQQSLFNYTIEASNFALFGERLGLLGHDLSPGSLKFIHALHSMFKSTSQLLFLPKSLTRWTSTRVWKEHFDAWDVISEYANRCIWKVHQELRLGSSQTYSGIVAELISQGSLPLDAIKANSMELTAGSVDTTAIPLVMTLFELARNPDVQKALRQESLAAEASIAANPQKAMSDLPLLRAALKETLRLYPVGGFLERILSSDLVLQNYHVPAGTLVLLYLYSMGRNPAVFPRPERYMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEMMLLLHHILKTFQVETLRQEDVQMAYRFVLMPSSSPVLTFRPVS", "length": 500 }, "evidence": [ { "id": "A0A5G2QWR0", "url": "https://omabrowser.org/oma/group/A0A5G2QWR0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ], "pmid": "" }, { "name": "steroid 11-beta-monooxygenase activity", "id": "GO:0004507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004507", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ], "pmid": "" }, { "name": "corticosterone 18-monooxygenase activity", "id": "GO:0047783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "steroid biosynthetic process", "id": "GO:0006694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006694", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ], "pmid": "" }, { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ], "pmid": "" }, { "name": "glucocorticoid biosynthetic process", "id": "GO:0006704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006704", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ], "pmid": "" }, { "name": "cellular response to peptide hormone stimulus", "id": "GO:0071375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071375", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ], "pmid": "" }, { "name": "aldosterone biosynthetic process", "id": "GO:0032342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032342", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ], "pmid": "" }, { "name": "cortisol metabolic process", "id": "GO:0034650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034650", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15629", "name": "", "equation": "a steroid + 2 reduced [adrenodoxin] + O2 + 2 H(+) = an 11beta-hydroxysteroid + 2 oxidized [adrenodoxin] + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "15629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15629" } ] }, { "id": "46104", "name": "", "equation": "21-hydroxyprogesterone + 2 reduced [adrenodoxin] + O2 + 2 H(+) = corticosterone + 2 oxidized [adrenodoxin] + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46104", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46104" } ] }, { "id": "R-SSC-193965", "name": "CYP11B2 oxidises 18HCORST to ALDO", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-194012" ], "output_participant_list": [ "R-ALL-193982" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-193965", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193965" } ] }, { "id": "R-SSC-193995", "name": "CYP11B2 18-hydroxylates CORST to 18HCORST", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-194005" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-193995", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193995" } ] }, { "id": "R-SSC-193997", "name": "CYP11B1 oxidises 11DCORT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-193998" ], "output_participant_list": [ "R-ALL-194011" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-193997", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193997" } ] }, { "id": "R-SSC-194017", "name": "CYP11B2 oxidises 11DCORST to CORST", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-193988" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-194017", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-194017" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-193982", "participant_name": "ALDO [mitochondrial matrix]", "crossref": [ { "id": "HMDB0000037", "database": "HMDB Metabolite", "url": "" }, { "id": "2872", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "27584", "database": "ChEBI", "url": "" }, { "id": "C01780", "database": "COMPOUND", "url": "" }, { "id": "ZINC000003833824", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-193988", "participant_name": "11DCORST [mitochondrial matrix]", "crossref": [ { "id": "16973", "database": "ChEBI", "url": "" }, { "id": "C03205", "database": "COMPOUND", "url": "" }, { "id": "ZINC000003833823", "database": "ZINC", "url": "" }, { "id": "HMDB0000016", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-193998", "participant_name": "11DCORT [mitochondrial matrix]", "crossref": [ { "id": "28324", "database": "ChEBI", "url": "" }, { "id": "C05488", "database": "COMPOUND", "url": "" }, { "id": "5100", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000003860956", "database": "ZINC", "url": "" }, { "id": "HMDB0000015", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-194005", "participant_name": "CORST [mitochondrial matrix]", "crossref": [ { "id": "16827", "database": "ChEBI", "url": "" }, { "id": "C02140", "database": "COMPOUND", "url": "" }, { "id": "2869", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000013513592", "database": "ZINC", "url": "" }, { "id": "HMDB0001547", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-194011", "participant_name": "CORT [mitochondrial matrix]", "crossref": [ { "id": "ZINC000013540519", "database": "ZINC", "url": "" }, { "id": "C00735", "database": "COMPOUND", "url": "" }, { "id": "17650", "database": "ChEBI", "url": "" }, { "id": "2868", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "HMDB0000063", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-194012", "participant_name": "18HCORST [mitochondrial matrix]", "crossref": [ { "id": "16485", "database": "ChEBI", "url": "" }, { "id": "C01124", "database": "COMPOUND", "url": "" }, { "id": "ZINC000004095550", "database": "ZINC", "url": "" }, { "id": "HMDB0000319", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWR0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 437, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWR0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWR0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3P3-1", "uniprot_ac": "A0A5G2R3P3", "uniprot_id": "A0A5G2R3P3_PIG", "mass": { "chemical_mass": 69673.0, "monoisotopic_mass": 69673.0 }, "refseq": { "ac": "XP_020920476", "name": "voltage-dependent L-type calcium channel subunit beta-2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920476" }, "gene_names": [ { "name": "CACNB2", "type": "recommended", "evidence": [ { "id": "A0A5G2R3P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ] }, { "name": "CACNB2", "type": "synonym", "evidence": [ { "id": "XP_020920476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920476" } ] } ], "protein_names": [ { "name": "Voltage-dependent L-type calcium channel subunit beta-2", "type": "recommended", "evidence": [ { "id": "A0A5G2R3P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3/entry#names_and_taxonomy" } ] }, { "name": "Calcium channel voltage-dependent subunit beta 2", "type": "synonym", "evidence": [ { "id": "A0A5G2R3P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3/entry#names_and_taxonomy" } ] }, { "name": "voltage-dependent L-type calcium channel subunit beta-2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_020920476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920476" } ] } ], "function": [ { "annotation": "Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current. Plays a role in shifting voltage dependencies of activation and inactivation of the channel. May modulate G protein inhibition. May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. Involved in membrane targeting of the alpha-1 subunit CACNA1C.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BIE3", "url": "https://www.uniprot.org/uniprotkb/A0A287BIE3#function" }, { "database": "UniProtKB", "id": "ARBA00046042", "url": "https://www.uniprot.org/uniprotkb/ARBA00046042#function" }, { "database": "UniProtKB", "id": "A0A287BSZ0", "url": "https://www.uniprot.org/uniprotkb/A0A287BSZ0#function" }, { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3#function" }, { "database": "UniProtKB", "id": "A0A286ZP52", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP52#function" }, { "database": "UniProtKB", "id": "A0A287A6B3", "url": "https://www.uniprot.org/uniprotkb/A0A287A6B3#function" }, { "database": "UniProtKB", "id": "A0A287AL78", "url": "https://www.uniprot.org/uniprotkb/A0A287AL78#function" }, { "database": "UniProtKB", "id": "A0A287B2G2", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G2#function" }, { "database": "UniProtKB", "id": "F1RWA1", "url": "https://www.uniprot.org/uniprotkb/F1RWA1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CACNB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3", "locus": { "chromosome": "10", "start_pos": 44886425, "end_pos": 44421485, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011040", "url": "https://www.ensembl.org/id/ENSSSCG00000011040" } ] } } ], "crossref": [ { "id": "A0A5G2R3P3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3P3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011040", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011040", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524101", "url": "https://www.ncbi.nlm.nih.gov/gene/100524101", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DSNFSHH", "url": "https://omabrowser.org/oma/group/DSNFSHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-112308", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112308", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-422356", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-422356", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5576892", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576892", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5576893", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576893", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020920476", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920476", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZP52", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZP52-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A6B3", "url": "https://www.uniprot.org/uniprotkb/A0A287A6B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A6B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A6B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AL78", "url": "https://www.uniprot.org/uniprotkb/A0A287AL78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AL78-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AL78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2G2", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIE3", "url": "https://www.uniprot.org/uniprotkb/A0A287BIE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BIE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BSZ0", "url": "https://www.uniprot.org/uniprotkb/A0A287BSZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BSZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BSZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R637", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R637", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R637-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R637-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCU8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWA1", "url": "https://www.uniprot.org/uniprotkb/F1RWA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWA1-1", "url": "https://www.uniprot.org/uniprotkb/F1RWA1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQAGGLDLLKISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVNYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTSPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPESFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPMSPTLASHSQGPPGDQRTDRSAPGRSASQVEEEACPELVRKPQHRSSSSAQHHNHRSGAGRGLSRQETLDSETQESRDSAYVEPKEDSCHEPVDHCAAHRDHSHREEPHGGGEHRHRESRHRARDPDREQDHNECSRQRSRHKFKDAEGLAKKRNEAGDCNRDVYIRQ", "length": 626, "header": "tr|A0A5G2R3P3-1|A0A5G2R3P3_PIG Isoform 1 of Voltage-dependent L-type calcium channel subunit beta-2 OS=Sus scrofa OX=9823 GN=CACNB2 PE=3 SV=1 CANONICAL=A0A5G2R3P3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZP52-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3/entry#A0A286ZP52-1", "sequence": { "sequence": "MVQSDMSKSPPTAAAAVAQEIQMELLENAAPAGALGAAAQSYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVNYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTSPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPESFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPMSPTLASHSQGPPGDQRTDRSAPGRSASQVEEEACPELVRKPQHRSSSSAQHHNHRSGAGRGLSRQETLDSETQESRDSAYVEPKEDSCHEPVDHCAAHRDHSHREEPHGGGEHRHRESRHRARDPDREQDHNECSRQRSRHKFKDAEGLAKKRNEAGDCNRDVYIRQ", "length": 654, "header": "tr|A0A286ZP52-1|A0A5G2R3P3_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-2 OS=Sus scrofa OX=9823 GN=CACNB2 PE=3 SV=2 CANONICAL=A0A5G2R3P3-1" }, "locus": { "chromosome": "10", "start_pos": 44885421, "end_pos": 44421684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038059.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038059.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033393.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033393.2" } ] } }, { "isoform_ac": "A0A287A6B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3/entry#A0A287A6B3-1", "sequence": { "sequence": "MYHDGREHSEAGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVNYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTSPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPESFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPMSPTLASHSQGPPGDQRTDRSAPGRSASQVEEEACPELVRKPQHRSSSSAQHHNHRSGAGRGLSRQETLDSETQESRDSAYVEPKEDSCHEPVDHCAAHRDHSHREEPHGGGEHRHRESRHRARDPDREQDHNECSRQRSRHKFKDAEGLAKKRNEAGDCNRDVYIRQ", "length": 594, "header": "tr|A0A287A6B3-1|A0A5G2R3P3_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-2 OS=Sus scrofa OX=9823 GN=CACNB2 PE=3 SV=2 CANONICAL=A0A5G2R3P3-1" }, "locus": { "chromosome": "10", "start_pos": 44885421, "end_pos": 44677872, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046405.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046405.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039340.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039340.2" } ] } }, { "isoform_ac": "A0A287AL78-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3/entry#A0A287AL78-1", "sequence": { "sequence": "MKATWIRLLKRAKGGRLKNSDICGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVNYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTSPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPESFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPMSPTLASHSQGPPGDQRTDRSAPGRSASQVEEEACPELVRKPQHRSSSSAQHHNHRSGAGRGLSRQETLDSETQESRDSAYVEPKEDSCHEPVDHCAAHRDHSHREEPHGGGEHRHRESRHRARDPDREQDHNECSRQRSRHKFKDAEGLAKKRNEAGDCNRDVYIRQ", "length": 606, "header": "tr|A0A287AL78-1|A0A5G2R3P3_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-2 OS=Sus scrofa OX=9823 GN=CACNB2 PE=3 SV=1 CANONICAL=A0A5G2R3P3-1" }, "locus": { "chromosome": "10", "start_pos": 44885421, "end_pos": 44727038, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052242.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052242.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044756.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044756.1" } ] } }, { "isoform_ac": "A0A287B2G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3/entry#A0A287B2G2-1", "sequence": { "sequence": "MKATWIRLLKRAKGGRLKNSDICGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVNYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTSPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPESFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPMSPTLASHSQGPPGDQRTDRSAPGRSASQVEEEACPELVRKPQHRSSSSAQHHNHRSGAGRGLSRQETLDSETQESRDSAYVEPKEDSCHEPVDHCAAHRDHSHREEPHGGGEHRHRESRHRARDPDREQDHNECSRQRSRHKFKDAEGLAKKRNEAGDCNRDVYIRQ", "length": 568, "header": "tr|A0A287B2G2-1|A0A5G2R3P3_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-2 OS=Sus scrofa OX=9823 GN=CACNB2 PE=3 SV=3 CANONICAL=A0A5G2R3P3-1" }, "locus": { "chromosome": "10", "start_pos": 44885421, "end_pos": 44727038, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061976.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061976.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050632.3", "url": "https://www.ensembl.org/id/ENSSSCP00000050632.3" } ] } }, { "isoform_ac": "A0A287BIE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3/entry#A0A287BIE3-1", "sequence": { "sequence": "MFDRRLLSPQTKGILPGGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVNYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTSPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPESFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPMSPTLASHSQGPPGDQRTDRSAPGRSASQVEEEACPELVRKPQHRSSSSAQHHNHRSGAGRGLSRQETLDSETQESRDSAYVEPKEDSCHEPVDHCAAHRDHSHREEPHGGGEHRHRESRHRARDPDREQDHNECSRQRSRHKFKDAEGLAKKRNEAGDCNRDVYIRQ", "length": 600, "header": "tr|A0A287BIE3-1|A0A5G2R3P3_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-2 OS=Sus scrofa OX=9823 GN=CACNB2 PE=3 SV=2 CANONICAL=A0A5G2R3P3-1" }, "locus": { "chromosome": "10", "start_pos": 44885421, "end_pos": 44653386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049791.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049791.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055839.2", "url": "https://www.ensembl.org/id/ENSSSCP00000055839.2" } ] } }, { "isoform_ac": "A0A287BSZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3/entry#A0A287BSZ0-1", "sequence": { "sequence": "MNQAGGLDLLKISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVNYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEHTSPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPESFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPMSPTLASHSQGPPGDQRTDRSAPGRSASQVEEEACPELVRKPQHRSSSSAQHHNHRSGAGRGLSRQETLDSETQESRDSAYVEPKEDSCHEPVDHCAAHRDHSHREEPHGGGEHRHRESRHRARDPDREQDHNECSRQRSRHKFKDAEGLAKKRNEAGDCNRDVYIRQ", "length": 602, "header": "tr|A0A287BSZ0-1|A0A5G2R3P3_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-2 OS=Sus scrofa OX=9823 GN=CACNB2 PE=3 SV=3 CANONICAL=A0A5G2R3P3-1" }, "locus": { "chromosome": "10", "start_pos": 44885421, "end_pos": 44422148, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057605.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057605.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059574.3", "url": "https://www.ensembl.org/id/ENSSSCP00000059574.3" } ] } }, { "isoform_ac": "A0A5G2R3P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3/entry#A0A5G2R3P3-1", "sequence": { "sequence": "MNQAGGLDLLKISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVNYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTSPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPESFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPMSPTLASHSQGPPGDQRTDRSAPGRSASQVEEEACPELVRKPQHRSSSSAQHHNHRSGAGRGLSRQETLDSETQESRDSAYVEPKEDSCHEPVDHCAAHRDHSHREEPHGGGEHRHRESRHRARDPDREQDHNECSRQRSRHKFKDAEGLAKKRNEAGDCNRDVYIRQ", "length": 626, "header": "tr|A0A5G2R3P3-1|A0A5G2R3P3_PIG Isoform 1 of Voltage-dependent L-type calcium channel subunit beta-2 OS=Sus scrofa OX=9823 GN=CACNB2 PE=3 SV=1 CANONICAL=A0A5G2R3P3-1" }, "locus": { "chromosome": "10", "start_pos": 44885421, "end_pos": 44422148, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070943.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070943.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068812.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068812.1" } ] } }, { "isoform_ac": "A0A5G2R637-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3/entry#A0A5G2R637-1", "sequence": { "sequence": "MFDRRLLSPQTKGILPGGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVNYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSDGAHFSIRCGPFYAASGLGGPFSEGV", "length": 195, "header": "tr|A0A5G2R637-1|A0A5G2R3P3_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-2 OS=Sus scrofa OX=9823 GN=CACNB2 PE=3 SV=2 CANONICAL=A0A5G2R3P3-1" }, "locus": { "chromosome": "10", "start_pos": 44849176, "end_pos": 44653386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075442.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075442.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071800.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071800.2" } ] } }, { "isoform_ac": "A0A8W4FCU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3/entry#A0A8W4FCU8-1", "sequence": { "sequence": "MQCCGLVHRRRARVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVNYSAAHEDDVPVPGMAISFEAKDFLHVKEVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPESFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPMSPTLASHSQGPPGDQRTDRSAPGRSASQVEEEACPELVRKPQHRSSSSAQHHNHRSGAGRGLSRQETLDSETQESRDSAYVEPKEDSCHEPVDHCAAHRDHSHREEPHGGGEHRHRESRHRARDPDREQDHNECSRQRSRHKFKDAEGLAKKRNEAGDCNRDVYIRQ", "length": 349, "header": "tr|A0A8W4FCU8-1|A0A5G2R3P3_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-2 OS=Sus scrofa OX=9823 GN=CACNB2 PE=3 SV=1 CANONICAL=A0A5G2R3P3-1" }, "locus": { "chromosome": "10", "start_pos": 44885421, "end_pos": 44560566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092725.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092725.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077141.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077141.1" } ] } }, { "isoform_ac": "F1RWA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3/entry#F1RWA1-1", "sequence": { "sequence": "MQCCGLVHRRRARVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVNYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTSPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPESFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPMSPTLASHSQGPPGDQRTDRSAPGRSASQVEEEACPELVRKPQHRSSSSAQHHNHRSGAGRGLSRQETLDSETQESRDSAYVEPKEDSCHEPVDHCAAHRDHSHREEPHGGGEHRHRESRHRARDPDREQDHNECSRQRSRHKFKDAEGLAKKRNEAGDCNRDVYIRQ", "length": 599, "header": "tr|F1RWA1-1|A0A5G2R3P3_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-2 OS=Sus scrofa OX=9823 GN=CACNB2 PE=3 SV=3 CANONICAL=A0A5G2R3P3-1" }, "locus": { "chromosome": "10", "start_pos": 44885421, "end_pos": 44560566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012084.4", "url": "https://www.ensembl.org/id/ENSSSCT00000012084.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011776.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011776.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A6B3", "url": "https://www.uniprot.org/uniprotkb/A0A287A6B3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-112308", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112308", "resource": "Reactome", "description": "Presynaptic depolarization and calcium channel opening" }, { "id": "R-SSC-422356", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-422356", "resource": "Reactome", "description": "Regulation of insulin secretion" }, { "id": "R-SSC-5576892", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576892", "resource": "Reactome", "description": "Phase 0 - rapid depolarisation" }, { "id": "R-SSC-5576893", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576893", "resource": "Reactome", "description": "Phase 2 - plateau phase" } ], "orthologs": [ { "uniprot_canonical_ac": "Q08289-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-2", "gene_name": "CACNB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ", "length": 660 }, "evidence": [ { "id": "A0A5G2R3P3", "url": "https://omabrowser.org/oma/group/A0A5G2R3P3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VGC3-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-2", "gene_name": "Cacnb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQSDTSKSPPIAAVAQESQMELLESAAPAGALGAQSYGKGARRKNRFKGSDDSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQESFDVILDENQLEDACEHLADYLEAYWKATHPPSSNLPNPLLSRTLATSTLPLSPTLASNSQGSQGDQRTDRSAPRSASQAEEEPCLEPVKKSQHRSSSATHQNHRSGTGRGLSRQETFDSETQESRDSAYVEPKEDYSHEHVDRYVPHREHNHREESHSSNGHRHREPRHRTRDMGRDQDHNECSKQRSRHKSKDRYCDKEGEVISKRRSEAGEWNRDVYIRQ", "length": 655 }, "evidence": [ { "id": "A0A5G2R3P3", "url": "https://omabrowser.org/oma/group/A0A5G2R3P3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9MZL5-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-2", "gene_name": "CACNB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQCCGLVHRRRARVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEDNDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPVSPTLASNSQGSQGDQRTDRGAPGRSASQAEEEHCPEPVKKAQHRSSTQHHNHRSGTSRGLSRQETLDSETQESRDSAYAEPKEEYSHEHADHYAPHRDHNHREEPHGGGEHRHREPRHRSRDPDREQDHNESNKQRSRHKSKDRYCDKDGEGLSRRRNEAADWNRDVYIRQ", "length": 603 }, "evidence": [ { "id": "A0A5G2R3P3", "url": "https://omabrowser.org/oma/group/A0A5G2R3P3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels", "id": "GO:0099626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099626", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "high voltage-gated calcium channel activity", "id": "GO:0008331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008331", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity involved in AV node cell action potential", "id": "GO:0086056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086056", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "regulation of heart rate by cardiac conduction", "id": "GO:0086091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086091", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "positive regulation of calcium ion transport", "id": "GO:0051928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051928", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "membrane depolarization during atrial cardiac muscle cell action potential", "id": "GO:0098912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098912", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "calcium ion import", "id": "GO:0070509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "L-type voltage-gated calcium channel complex", "id": "GO:1990454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990454", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "photoreceptor ribbon synapse", "id": "GO:0098684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098684", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R3P3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 626, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R3P3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3P3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R3P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3P3" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 155, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R520-1", "uniprot_ac": "A0A5G2R520", "uniprot_id": "A0A5G2R520_PIG", "mass": { "chemical_mass": 21556.0, "monoisotopic_mass": 21556.0 }, "refseq": {}, "gene_names": [ { "name": "HOXD8", "type": "recommended", "evidence": [ { "id": "A0A5G2R520", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520" } ] } ], "protein_names": [ { "name": "Homeobox protein Hox-D8", "type": "recommended", "evidence": [ { "id": "A0A5G2R520", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BGU6", "url": "https://www.uniprot.org/uniprotkb/A0A287BGU6#function" }, { "database": "UniProtKB", "id": "ARBA00003263", "url": "https://www.uniprot.org/uniprotkb/ARBA00003263#function" }, { "database": "UniProtKB", "id": "A0A5G2QGQ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGQ7#function" }, { "database": "UniProtKB", "id": "A0A5G2R520", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R520", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HOXD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520", "locus": { "chromosome": "15", "start_pos": 81935529, "end_pos": 81931010, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040349", "url": "https://www.ensembl.org/id/ENSSSCG00000040349" } ] } } ], "crossref": [ { "id": "A0A5G2R520", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R520", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000040349", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000040349", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515172", "url": "https://www.ncbi.nlm.nih.gov/gene/100515172", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CHREPAK", "url": "https://omabrowser.org/oma/group/CHREPAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46166:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46166:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287BGU6", "url": "https://www.uniprot.org/uniprotkb/A0A287BGU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BGU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BGU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QGQ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QGQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R520", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R520-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPERQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEAKDGETKKEAQELEEDRAEGPTN", "length": 186, "header": "tr|A0A5G2R520-1|A0A5G2R520_PIG Isoform 1 of Homeobox protein Hox-D8 OS=Sus scrofa OX=9823 GN=HOXD8 PE=3 SV=1 CANONICAL=A0A5G2R520-1" }, "isoforms": [ { "isoform_ac": "A0A287BGU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520/entry#A0A287BGU6-1", "sequence": { "sequence": "MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAGFPHAPPQAHAHPHPSPPPARPGCGGGGGPGPGQDYFHPGGGSPAAAYQAAPPPPPPPPPPPPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEAKDGETKKEAQELEEDRAEGPTN", "length": 290, "header": "tr|A0A287BGU6-1|A0A5G2R520_PIG Computationally mapped isoform of Homeobox protein Hox-D8 OS=Sus scrofa OX=9823 GN=HOXD8 PE=3 SV=3 CANONICAL=A0A5G2R520-1" }, "locus": { "chromosome": "15", "start_pos": 81932880, "end_pos": 81931633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060973.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060973.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055275.3", "url": "https://www.ensembl.org/id/ENSSSCP00000055275.3" } ] } }, { "isoform_ac": "A0A5G2QGQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520/entry#A0A5G2QGQ7-1", "sequence": { "sequence": "MFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEAKDGETKKEAQELEEDRAEGPTN", "length": 106, "header": "tr|A0A5G2QGQ7-1|A0A5G2QGQ7_PIG Computationally mapped isoform of Homeobox protein Hox-D8 OS=Sus scrofa OX=9823 GN=HOXD8 PE=3 SV=1 CANONICAL=A0A5G2R520-1" }, "locus": { "chromosome": "15", "start_pos": 81932880, "end_pos": 81932188, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090436.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090436.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062993.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062993.1" } ] } }, { "isoform_ac": "A0A5G2R520-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520/entry#A0A5G2R520-1", "sequence": { "sequence": "MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPERQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEAKDGETKKEAQELEEDRAEGPTN", "length": 186, "header": "tr|A0A5G2R520-1|A0A5G2R520_PIG Isoform 1 of Homeobox protein Hox-D8 OS=Sus scrofa OX=9823 GN=HOXD8 PE=3 SV=1 CANONICAL=A0A5G2R520-1" }, "locus": { "chromosome": "15", "start_pos": 81932880, "end_pos": 81931633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106353.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106353.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076569.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076569.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BGU6", "url": "https://www.uniprot.org/uniprotkb/A0A287BGU6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZP54-1", "protein_name": "Homeobox protein Hox-D8", "gene_name": "Hoxd8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EVAPGRGCVFFSSPCRAGAREPKPKRLPRGPGALFSSSRCARAAWCLGGNWRPRGRSPGRRRFYCGPAGARRERLAGRRRAGAGEAINPTYYDCHFAPEVSGRHAAALQLYGNSAAGFPHAPPQAHAHPHPSPPPGCGGGGGPGPGQNYFHAGAGSPVAAYQAAPPPPPHPPPPPPPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHTLALTERQVKIWFQNRRMKWKKENNRDKFPASRPEAKDGDPKKEVSGLEEDGAEGPTN", "length": 345 }, "evidence": [ { "id": "A0A5G2R520", "url": "https://omabrowser.org/oma/group/A0A5G2R520/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9SQJ0-1", "protein_name": "Homeobox protein Hox-D8", "gene_name": "HOXD8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSYFVNPLYSKYKAAAAAGEAINPTYYDCHFAPERQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEAKDGETKKEAQELEEDRAEGPTN", "length": 182 }, "evidence": [ { "id": "A0A5G2R520", "url": "https://omabrowser.org/oma/group/A0A5G2R520/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P13378-1", "protein_name": "Homeobox protein Hox-D8", "gene_name": "HOXD8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAGFPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPPPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN", "length": 290 }, "evidence": [ { "id": "A0A5G2R520", "url": "https://omabrowser.org/oma/group/A0A5G2R520/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P23463-1", "protein_name": "Homeobox protein Hox-D8", "gene_name": "Hoxd8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSYFVNPLYSKYKAAAAAAAAAAAAAAGEAINPTYYDCHFAPEVSGRHAAALQLYGNSAAGFPHAHPHPHPHPSPPPGCGGGGGPGPGQDYFHAGAGSPTAAYQAAPPPPHPPPPPPPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHTLALTERQVKIWFQNRRMKWKKENNKDKFPASRPEAKDGDPKKEVSGLEEDGAEGCPTN", "length": 289 }, "evidence": [ { "id": "A0A5G2R520", "url": "https://omabrowser.org/oma/group/A0A5G2R520/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R520", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R520", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R520", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R520", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R520", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R520", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R520", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R520-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 186, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R520-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R520" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R520", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R520" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 151, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R4Q2-1", "uniprot_ac": "A0A5G2R4Q2", "uniprot_id": "A0A5G2R4Q2_PIG", "mass": { "chemical_mass": 51034.0, "monoisotopic_mass": 51034.0 }, "refseq": {}, "gene_names": [ { "name": "SLC30A6", "type": "recommended", "evidence": [ { "id": "A0A5G2R4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2" } ] } ], "protein_names": [ { "name": "Zinc transporter 6", "type": "recommended", "evidence": [ { "id": "A0A5G2R4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 30 member 6", "type": "synonym", "evidence": [ { "id": "A0A5G2R4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway. As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0WIE9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WIE9#function" }, { "database": "UniProtKB", "id": "ARBA00045455", "url": "https://www.uniprot.org/uniprotkb/ARBA00045455#function" }, { "database": "UniProtKB", "id": "A0A4X1TBB6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TBB6#function" }, { "database": "UniProtKB", "id": "A0A5G2R4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2#function" }, { "database": "UniProtKB", "id": "A0A5K1UU83", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UU83#function" }, { "database": "UniProtKB", "id": "A0A287AH42", "url": "https://www.uniprot.org/uniprotkb/A0A287AH42#function" }, { "database": "UniProtKB", "id": "A0A287AYQ2", "url": "https://www.uniprot.org/uniprotkb/A0A287AYQ2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC30A6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2", "locus": { "chromosome": "3", "start_pos": 107387860, "end_pos": 107426337, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008518", "url": "https://www.ensembl.org/id/ENSSSCG00000008518" } ] } } ], "crossref": [ { "id": "A0A5G2R4Q2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4Q2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008518", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008518", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100170144", "url": "https://www.ncbi.nlm.nih.gov/gene/100170144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8D0WIE9", "url": "https://www.orthodb.org/?gene=A0A8D0WIE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46531", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46531", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46531:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46531:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01545", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01545", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AH42", "url": "https://www.uniprot.org/uniprotkb/A0A287AH42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AH42-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AH42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AYQ2", "url": "https://www.uniprot.org/uniprotkb/A0A287AYQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AYQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AYQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TBB6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TBB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TBB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TBB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UU83", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UU83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UU83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UU83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0WIE9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WIE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0WIE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WIE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KGTIHLFRKPQRSFFGKLLQEFRLVAADRRSWKILFFGAINLTCTGFLLMWCSSTNSIALTAYTYLTIFDLFSLMTCLISYWVMMRKPSPAYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALSFNLFTMLSVRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPALLSGPVAANVLNFSDHHIIPMPPSKCADDSNPVTSTPAKPSSPPPEFSFNTPGKNVSPVILLNTQTRPYGLGLNHGHTPYSNMLNQGLGIPGIGATQGFRTGFTNIPSRYGTNNRIGQPRS", "length": 461, "header": "tr|A0A5G2R4Q2-1|A0A5G2R4Q2_PIG Isoform 1 of Zinc transporter 6 OS=Sus scrofa OX=9823 GN=SLC30A6 PE=3 SV=2 CANONICAL=A0A5G2R4Q2-1" }, "isoforms": [ { "isoform_ac": "A0A287AH42-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2/entry#A0A287AH42-1", "sequence": { "sequence": "MSWKILFFGAINLTCTGFLLMWCSSTNSILMTCLISYWVMMRKPSPAYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALSFNLFTMLSVRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPALLSGPVAANVLNFSDHHIIPMPPSKCADDSNPVTSTPAKPSSPPPEFSFNTPGKNVSPVILLNTQTRPYGLGLNHGHTPYSNMLNQGLGIPGIGATQGFRTGFTNIPSRYGTNNRIGQPRS", "length": 417, "header": "tr|A0A287AH42-1|A0A5G2R4Q2_PIG Computationally mapped isoform of Zinc transporter 6 OS=Sus scrofa OX=9823 GN=SLC30A6 PE=3 SV=3 CANONICAL=A0A5G2R4Q2-1" }, "locus": { "chromosome": "3", "start_pos": 107426294, "end_pos": 107390840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052851.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052851.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043193.3", "url": "https://www.ensembl.org/id/ENSSSCP00000043193.3" } ] } }, { "isoform_ac": "A0A287AYQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2/entry#A0A287AYQ2-1", "sequence": { "sequence": "MGTIHLFRKPQRSFFGKLLQEFRLVAADRRSWKILFFGAINLTCTGFLLMWCSSTNSILMTCLISYWVMMRKPSPAYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALSFNLFTMLSVRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPALLSGPVAANVLNFSDHHIIPMPPSKCADDSNPVTSTPAKPSSPPPEFSFNTPGKNVSPVILLNTQTRPYGLGLNHGHTPYSNMLNQGLGIPGIGATQGFRTGFTNIPSRYGTNNRIGQPRS", "length": 446, "header": "tr|A0A287AYQ2-1|A0A5G2R4Q2_PIG Computationally mapped isoform of Zinc transporter 6 OS=Sus scrofa OX=9823 GN=SLC30A6 PE=3 SV=2 CANONICAL=A0A5G2R4Q2-1" }, "locus": { "chromosome": "3", "start_pos": 107426294, "end_pos": 107390840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043276.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043276.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049280.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049280.2" } ] } }, { "isoform_ac": "A0A4X1TBB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2/entry#A0A4X1TBB6-1", "sequence": { "sequence": "IKPQRSFFGKLLQEFRLVAADRRSWKILFFGAINLTCTGFLLMWCSSTNSIALTAYTYLTIFDLFSLMTCLISYWVMMRKPSPAYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALSFNLFTMLSVRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPALLSGPVAANVLNFSDHHIIPMPPSKCADDSNPVTSTPAKPSSPPPEFSFNTPGKNVSPVILLNTQTRPYGLGLNHGHTPYSNMLNQGLGIPGIGATQGFRTGFTNIPSRYGTNNRIGQPRS", "length": 454, "header": "tr|A0A4X1TBB6-1|A0A4X1TBB6_PIG Computationally mapped isoform of Zinc transporter 6 OS=Sus scrofa OX=9823 GN=SLC30A6 PE=3 SV=1 CANONICAL=A0A5G2R4Q2-1" }, "locus": { "chromosome": "3", "start_pos": 107421781, "end_pos": 107390840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041509.2", "url": "https://www.ensembl.org/id/ENSSSCT00000041509.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047388.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047388.2" } ] } }, { "isoform_ac": "A0A5G2R4Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2/entry#A0A5G2R4Q2-1", "sequence": { "sequence": "KGTIHLFRKPQRSFFGKLLQEFRLVAADRRSWKILFFGAINLTCTGFLLMWCSSTNSIALTAYTYLTIFDLFSLMTCLISYWVMMRKPSPAYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALSFNLFTMLSVRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPALLSGPVAANVLNFSDHHIIPMPPSKCADDSNPVTSTPAKPSSPPPEFSFNTPGKNVSPVILLNTQTRPYGLGLNHGHTPYSNMLNQGLGIPGIGATQGFRTGFTNIPSRYGTNNRIGQPRS", "length": 461, "header": "tr|A0A5G2R4Q2-1|A0A5G2R4Q2_PIG Isoform 1 of Zinc transporter 6 OS=Sus scrofa OX=9823 GN=SLC30A6 PE=3 SV=2 CANONICAL=A0A5G2R4Q2-1" }, "locus": { "chromosome": "3", "start_pos": 107421752, "end_pos": 107390840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082965.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082965.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069165.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069165.2" } ] } }, { "isoform_ac": "A0A5K1UU83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2/entry#A0A5K1UU83-1", "sequence": { "sequence": "MGTIHLFRKPQRSFFGKLLQEFRLVAADRRSWKILFFGAINLTCTGFLLMWCSSTNSILMTCLISYWVMMRKPSPAYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALSFNLFTMLSVRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPALLSGPVAANVLNFSDHHIIPMPPSKCADDSNPVTSTPAKPSSPPPEFSFNTPGKNVSPVILLNTQTRPYGLGLNHGHTPYSNMLNQGLGIPGIGATQGFRTGFTNIPSRYGTNNRIGQPRS", "length": 423, "header": "tr|A0A5K1UU83-1|A0A5K1UU83_PIG Computationally mapped isoform of Zinc transporter 6 OS=Sus scrofa OX=9823 GN=SLC30A6 PE=3 SV=2 CANONICAL=A0A5G2R4Q2-1" }, "locus": { "chromosome": "3", "start_pos": 107426294, "end_pos": 107390840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009322.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009322.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009084.5", "url": "https://www.ensembl.org/id/ENSSSCP00000009084.5" } ] } }, { "isoform_ac": "A0A8D0WIE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2/entry#A0A8D0WIE9-1", "sequence": { "sequence": "MFTAVTGTIHLFRKPQRSFFGKLLQEFRLVAADRRSWKILFFGAINLTCTGFLLMWCSSTNSIALTAYTYLTIFDLFSLMTCLISYWVMMRKPSPAYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALSFNLFTMLSVRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPALLSGPVAANVLNFSDHHIIPMPPSKCADDSNPVTSTPAKPSSPPPEFSFNTPGKNVSPVILLNTQTRPYGLGLNHGHTPYSNMLNQGLGIPGIGATQGFRTGFTNIPSRYGTNNRIGQPRS", "length": 466, "header": "tr|A0A8D0WIE9-1|A0A5G2R4Q2_PIG Computationally mapped isoform of Zinc transporter 6 OS=Sus scrofa OX=9823 GN=SLC30A6 PE=3 SV=1 CANONICAL=A0A5G2R4Q2-1" }, "locus": { "chromosome": "3", "start_pos": 107425924, "end_pos": 107390840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038324.2", "url": "https://www.ensembl.org/id/ENSSSCT00000038324.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053533.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053533.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 376, "start_aa": "Thr", "end_pos": 376, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr376", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0WIE9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WIE9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "zinc ion transport", "id": "GO:0006829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2" } ], "pmid": "" }, { "name": "regulation of zinc ion transport", "id": "GO:0071579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071579", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2" } ], "pmid": "" }, { "name": "zinc ion import into Golgi lumen", "id": "GO:1904257", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904257", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R4Q2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 461, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R4Q2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4Q2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Q2" }, { "id": "PF01545", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01545" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cation efflux protein transmembrane", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 255, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 376 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 352, "end_pos": 354 }, { "start_pos": 395, "end_pos": 397 }, { "start_pos": 41, "end_pos": 43 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3X7-1", "uniprot_ac": "A0A5G2R3X7", "uniprot_id": "A0A5G2R3X7_PIG", "mass": { "chemical_mass": 119959.0, "monoisotopic_mass": 119959.0 }, "refseq": {}, "gene_names": [ { "name": "AP3B2", "type": "recommended", "evidence": [ { "id": "A0A5G2R3X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ] } ], "protein_names": [ { "name": "AP-3 complex subunit beta", "type": "recommended", "evidence": [ { "id": "A0A5G2R3X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F9H0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9H0#function" }, { "database": "UniProtKB", "id": "ARBA00023570", "url": "https://www.uniprot.org/uniprotkb/ARBA00023570#function" }, { "database": "UniProtKB", "id": "I3LRS3", "url": "https://www.uniprot.org/uniprotkb/I3LRS3#function" }, { "database": "UniProtKB", "id": "F1RI97", "url": "https://www.uniprot.org/uniprotkb/F1RI97#function" }, { "database": "UniProtKB", "id": "A0A5G2QYL3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL3#function" }, { "database": "UniProtKB", "id": "A0A5G2R1U4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1U4#function" }, { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AP3B2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7", "locus": { "chromosome": "7", "start_pos": 52294149, "end_pos": 52256159, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001807", "url": "https://www.ensembl.org/id/ENSSSCG00000001807" } ] } } ], "crossref": [ { "id": "A0A5G2R3X7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3X7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001807", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001807", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026740", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026740", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24080", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24080", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QYL3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1U4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1U4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RK43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RK43-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6J1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9H0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGU8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RI97", "url": "https://www.uniprot.org/uniprotkb/F1RI97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RI97-1", "url": "https://www.uniprot.org/uniprotkb/F1RI97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LRS3", "url": "https://www.uniprot.org/uniprotkb/I3LRS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LRS3-1", "url": "https://www.uniprot.org/uniprotkb/I3LRS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENPEKAFYGSEEDEAKGPGSEEAAATTLPARKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSSREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGGSSSESDNEDQDEDEEKGRSSESDQSEEEGKKRQMKKRKKVPEGQEGGSSSDEGSDSSSSSSESEMTSETEEEQVEPASWRKKTPSSSKSAPAAKEISLLDLEDSSFTPTVTPPSIQPVSSPAVVSTSLAADLEGLTLTDSPLAPSLLSPVSGVGRQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSDTPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAIMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKEQGKLTGMNEITEKLTLPDTCRSDHIVVQKVTATANLGRVPCGTSDEYRFAGRTLTSGSLVLLTLDARPTGAAQLTVNSEKMVIGTMLVKDVVQALTQ", "length": 1091, "header": "tr|A0A5G2R3X7-1|A0A5G2R3X7_PIG Isoform 1 of AP-3 complex subunit beta OS=Sus scrofa OX=9823 GN=AP3B2 PE=1 SV=1 CANONICAL=A0A5G2R3X7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7/entry#A0A5G2QYL3-1", "sequence": { "sequence": "MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENPEKAFYGSEEDEAKGPGSEEAAATTLPARKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSSREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGGSSSESDNEDQDEDEEKGRSSESDQSEEEGKKRQMKKRKKVPEGQEGGSSSDEGSDSSSSSSESEMTSETEEEQVEPASWRKKTPSSSKSAPAAKEISLLDLEDFTPPSIQPVSSPAVVSTSLAADLEGLTLTDSPLAPSLLSPVSGVGRQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSDTPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAIMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKEQGKLTGMNEITEKLTLPDTCRSDHIVVQKVTATANLGRVPCGTSDEYRFAGRTLTSGSLVLLTLDARPTGAAQLTVNSEKMVIGTMLVKDVVQALTQ", "length": 1053, "header": "tr|A0A5G2QYL3-1|A0A5G2QYL3_PIG Computationally mapped isoform of AP-3 complex subunit beta OS=Sus scrofa OX=9823 GN=AP3B2 PE=1 SV=1 CANONICAL=A0A5G2R3X7-1" }, "locus": { "chromosome": "7", "start_pos": 52293834, "end_pos": 52256714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085197.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085197.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063309.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063309.1" } ] } }, { "isoform_ac": "A0A5G2R1U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7/entry#A0A5G2R1U4-1", "sequence": { "sequence": "MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENPEKAFYGSEEDEAKGPGSEEAAATTLPARKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEEEDLSLIETHVGLLGEYTEVPEWTKCSSREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGGSSSESDNEDQDEDEEKGRSSESDQSEEEGKKRQMKKRKKVPEGQEGGSSSDEGSDSSSSSSESEMTSETEEEQVEPASWRKKTPSSSKSAPAAKEISLLDLEDFTPPSIQPVSSPAVVSTSLAADLEGLTLTDSPLAPSLLSPVSGVGRQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSDTPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAIMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKEQGKLTGMNEITEKLTLPDTCRSDHIVVQKVTATANLGRVPCGTSDEYRFAGRTLTSGSLVLLTLDARPTGAAQLTVNSEKMVIGTMLVKDVVQALTQ", "length": 1104, "header": "tr|A0A5G2R1U4-1|A0A5G2R1U4_PIG Computationally mapped isoform of AP-3 complex subunit beta OS=Sus scrofa OX=9823 GN=AP3B2 PE=1 SV=1 CANONICAL=A0A5G2R3X7-1" }, "locus": { "chromosome": "7", "start_pos": 52293834, "end_pos": 52256714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080895.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080895.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068162.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068162.1" } ] } }, { "isoform_ac": "A0A5G2R3X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7/entry#A0A5G2R3X7-1", "sequence": { "sequence": "MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENPEKAFYGSEEDEAKGPGSEEAAATTLPARKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSSREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGGSSSESDNEDQDEDEEKGRSSESDQSEEEGKKRQMKKRKKVPEGQEGGSSSDEGSDSSSSSSESEMTSETEEEQVEPASWRKKTPSSSKSAPAAKEISLLDLEDSSFTPTVTPPSIQPVSSPAVVSTSLAADLEGLTLTDSPLAPSLLSPVSGVGRQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSDTPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAIMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKEQGKLTGMNEITEKLTLPDTCRSDHIVVQKVTATANLGRVPCGTSDEYRFAGRTLTSGSLVLLTLDARPTGAAQLTVNSEKMVIGTMLVKDVVQALTQ", "length": 1091, "header": "tr|A0A5G2R3X7-1|A0A5G2R3X7_PIG Isoform 1 of AP-3 complex subunit beta OS=Sus scrofa OX=9823 GN=AP3B2 PE=1 SV=1 CANONICAL=A0A5G2R3X7-1" }, "locus": { "chromosome": "7", "start_pos": 52293834, "end_pos": 52256714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089909.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089909.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065256.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065256.2" } ] } }, { "isoform_ac": "A0A5G2RK43-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7/entry#A0A5G2RK43-1", "sequence": { "sequence": "MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKPLIKAASNMDHLSPRV", "length": 136, "header": "tr|A0A5G2RK43-1|A0A5G2R3X7_PIG Computationally mapped isoform of AP-3 complex subunit beta OS=Sus scrofa OX=9823 GN=AP3B2 PE=1 SV=1 CANONICAL=A0A5G2R3X7-1" }, "locus": { "chromosome": "7", "start_pos": 52267614, "end_pos": 52256714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072468.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072468.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072390.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072390.1" } ] } }, { "isoform_ac": "A0A8W4F6J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7/entry#A0A8W4F6J1-1", "sequence": { "sequence": "MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENPEKAFYGSEEDEAKGPGSEEAAATTLPARKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSSREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGGSSSESDNEDQDEDEEKGRSSESDQSEEEGKKRQMKKRKKVPEGQEGGSSSDEGSDSSSSSSESEMTSETEEEQVEPASWRKKTPSSSKSAPAAKEISLLDLEDFTPPSIQPVSSPAVVSTSLAADLEGLTLTDSPLAPSLLSPVSGVGRQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSDTPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAIMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKEQGLQGGH", "length": 995, "header": "tr|A0A8W4F6J1-1|A0A5G2R3X7_PIG Computationally mapped isoform of AP-3 complex subunit beta OS=Sus scrofa OX=9823 GN=AP3B2 PE=1 SV=1 CANONICAL=A0A5G2R3X7-1" }, "locus": { "chromosome": "7", "start_pos": 52293703, "end_pos": 52256714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098044.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098044.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074779.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074779.1" } ] } }, { "isoform_ac": "A0A8W4F9H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7/entry#A0A8W4F9H0-1", "sequence": { "sequence": "MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVADPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENPEKAFYGSEEDEAKGPGSEEAAATTLPARKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSSREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGGSSSESDNEDQDEDEEKGRSSESDQSEEEGKKRQMKKRKKVPEGQEGGSSSDEGSDSSSSSSESEMTSETEEEQVEPASWRKKTPSSSKSAPAAKEISLLDLEDFTPPSIQPVSSPAVVSTSLAADLEGLTLTDSPLAPSLLSPVSGVGRQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSDTPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAIMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKEQGKLTGMNEITEKLTLPDTCRSDHIVVQKVTATANLGRVPCGTSDEYRFAGRTLTSGSLVLLTLDARPTGAAQLTVNSEKMVIGTMLVKDVVQALTQ", "length": 1028, "header": "tr|A0A8W4F9H0-1|A0A5G2R3X7_PIG Computationally mapped isoform of AP-3 complex subunit beta OS=Sus scrofa OX=9823 GN=AP3B2 PE=1 SV=1 CANONICAL=A0A5G2R3X7-1" }, "locus": { "chromosome": "7", "start_pos": 52293834, "end_pos": 52256714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096046.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096046.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075476.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075476.1" } ] } }, { "isoform_ac": "A0A8W4FGU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7/entry#A0A8W4FGU8-1", "sequence": { "sequence": "MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKVRGLTLPPGVRASLALYWRSEPVGM", "length": 145, "header": "tr|A0A8W4FGU8-1|A0A5G2R3X7_PIG Computationally mapped isoform of AP-3 complex subunit beta OS=Sus scrofa OX=9823 GN=AP3B2 PE=1 SV=1 CANONICAL=A0A5G2R3X7-1" }, "locus": { "chromosome": "7", "start_pos": 52267498, "end_pos": 52256714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097522.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097522.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078101.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078101.1" } ] } }, { "isoform_ac": "A0A8W4FQJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7/entry#A0A8W4FQJ8-1", "sequence": { "sequence": "MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENPEKAFYGSEEDEAKGPGSEEAAATTLPARKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVSWWKGKRGDT", "length": 507, "header": "tr|A0A8W4FQJ8-1|A0A5G2R3X7_PIG Computationally mapped isoform of AP-3 complex subunit beta OS=Sus scrofa OX=9823 GN=AP3B2 PE=1 SV=1 CANONICAL=A0A5G2R3X7-1" }, "locus": { "chromosome": "7", "start_pos": 52277627, "end_pos": 52256714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105319.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105319.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081301.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081301.1" } ] } }, { "isoform_ac": "F1RI97-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7/entry#F1RI97-1", "sequence": { "sequence": "MSAAPAYSEDKGGSAGPGEPEYGHDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENPEKAFYGSEEDEAKGPGSEEAAATTLPARKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSSREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGGSSSESDNEDQDEDEEKGRSSESDQSEEEGKKRQMKKRKKVPEGQEGGSSSDEGSDSSSSSSESEMTSETEEEQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSDTPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAIMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKEQGKLTGMNEITEKLTLPDTCRSDHIVVQKVTATANLGRVPCGTSDEYRFAGRTLTSGSLVLLTLDARPTGAAQLTVNSEKMVIGTMLVKDVVQALTQ", "length": 1008, "header": "tr|F1RI97-1|A0A5G2R3X7_PIG Computationally mapped isoform of AP-3 complex subunit beta OS=Sus scrofa OX=9823 GN=AP3B2 PE=1 SV=3 CANONICAL=A0A5G2R3X7-1" }, "locus": { "chromosome": "7", "start_pos": 52293834, "end_pos": 52256714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002023.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002023.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001974.4", "url": "https://www.ensembl.org/id/ENSSSCP00000001974.4" } ] } }, { "isoform_ac": "I3LRS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7/entry#I3LRS3-1", "sequence": { "sequence": "MQRFLQLPGAVGRPGGRGACGADQEAASPVLAPEGGPPPWYQALQPEELRWLQAPEEDTTPETSLEGPCPEPGQGQSQNQPLRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENPEKAFYGSEEDEAKGPGSEEAAATTLPARKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSEQGGALSRHAKKLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSSREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGGSSSESDNEDQDEDEEKGRSSESDQSEEEGKKRQMKKRKKVPEGQEGGSSSDEGSDSSSSSSESEMTSETEEEQVEPASWRKKTPSSSKSAPAAKEISLLDLEDFTPPSIQPVSSPAVVSTSLAADLEGLTLTDSPLAPSLLSPVSGVGRQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSDTPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAIMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKEQGKLTGMNEITEKLTLPDTCRSDHIVVQKVTATANLGRVPCGTSDEYRFAGRTLTSGSLVLLTLDARPTGAAQLTVNSEKMVIGTMLVKDVVQALTQ", "length": 1130, "header": "tr|I3LRS3-1|A0A5G2R3X7_PIG Computationally mapped isoform of AP-3 complex subunit beta OS=Sus scrofa OX=9823 GN=AP3B2 PE=1 SV=3 CANONICAL=A0A5G2R3X7-1" }, "locus": { "chromosome": "7", "start_pos": 52293834, "end_pos": 52260518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024280.3", "url": "https://www.ensembl.org/id/ENSSSCT00000024280.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026812.3", "url": "https://www.ensembl.org/id/ENSSSCP00000026812.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 688, "start_aa": "Thr", "end_pos": 688, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr688", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6J1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "pmid": "" }, { "name": "anterograde synaptic vesicle transport", "id": "GO:0048490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048490", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "pmid": "" }, { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "pmid": "" }, { "name": "AP-3 adaptor complex", "id": "GO:0030123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030123", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "pmid": "" }, { "name": "clathrin-coated vesicle membrane", "id": "GO:0030665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030665", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "pmid": "" }, { "name": "membrane coat", "id": "GO:0030117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030117", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 906, "end_pos": 908, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R3X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X7" }, { "id": "SM01355", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01355" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-3 complex subunit beta C-terminal", "eco_id": "ECO_0000259", "start_pos": 804, "end_pos": 956, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 688 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 }, { "start_pos": 403, "end_pos": 405 }, { "start_pos": 70, "end_pos": 72 }, { "start_pos": 906, "end_pos": 908 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZX7-1", "uniprot_ac": "A0A5G2QZX7", "uniprot_id": "A0A5G2QZX7_PIG", "mass": { "chemical_mass": 84744.0, "monoisotopic_mass": 84744.0 }, "refseq": {}, "gene_names": [ { "name": "CLCN4", "type": "recommended", "evidence": [ { "id": "A0A5G2QZX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ] } ], "protein_names": [ { "name": "Chloride channel protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QZX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CLCN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7", "locus": { "chromosome": "X", "start_pos": 7019738, "end_pos": 6939387, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000024809", "url": "https://www.ensembl.org/id/ENSSSCG00000024809" } ] } } ], "crossref": [ { "id": "A0A5G2QZX7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000024809", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000024809", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03684", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03684", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04591", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04591", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45711:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45711:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B7R6", "url": "https://www.uniprot.org/uniprotkb/A0A287B7R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B7R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B7R6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGW3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVHAGVMSGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKSRDTDRHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFEDRDKCPLWQKWSELLVNQSEGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSIPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGLFIRCNIAWCRRRKTTRLGKYPVLEVIAVTAITAIVAYPNPYTRRSTSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGVGVYTAMWQLALALIFKIVITIFTFGMKIPSGLFIPSMAVGAMAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEPPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSRDSERLIGFAQRRELILAIKNARQRQEGIVSDSVMYFTEEPPELPANSPHPLKLRRVLNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMANQDPESIMFN", "length": 758, "header": "tr|A0A5G2QZX7-1|A0A5G2QZX7_PIG Isoform 1 of Chloride channel protein OS=Sus scrofa OX=9823 GN=CLCN4 PE=1 SV=1 CANONICAL=A0A5G2QZX7-1" }, "isoforms": [ { "isoform_ac": "A0A287B7R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7/entry#A0A287B7R6-1", "sequence": { "sequence": "MVHAGVMSGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKSRDTDRHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFEDRDKCPLWQKWSELLVNQSEGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSIPFGNSRLVLFYVEYHTPWRRKTTRLGKYPVLEVIAVTAITAIVAYPNPYTRRSTSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGVGVYTAMWQLALALIFKIVITIFTFGMKIPSGLFIPSMAVGAMAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEPPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSRDSERLIGFAQRRELILAIKNARQRQEGIVSDSVMYFTEEPPELPANSPHPLKLRRVLNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMANQDPESIMFN", "length": 728, "header": "tr|A0A287B7R6-1|A0A5G2QZX7_PIG Computationally mapped isoform of Chloride channel protein OS=Sus scrofa OX=9823 GN=CLCN4 PE=1 SV=2 CANONICAL=A0A5G2QZX7-1" }, "locus": { "chromosome": "X", "start_pos": 7017731, "end_pos": 6977125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022263.4", "url": "https://www.ensembl.org/id/ENSSSCT00000022263.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052560.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052560.2" } ] } }, { "isoform_ac": "A0A5G2QZX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7/entry#A0A5G2QZX7-1", "sequence": { "sequence": "MVHAGVMSGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKSRDTDRHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFEDRDKCPLWQKWSELLVNQSEGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSIPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGLFIRCNIAWCRRRKTTRLGKYPVLEVIAVTAITAIVAYPNPYTRRSTSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGVGVYTAMWQLALALIFKIVITIFTFGMKIPSGLFIPSMAVGAMAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEPPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSRDSERLIGFAQRRELILAIKNARQRQEGIVSDSVMYFTEEPPELPANSPHPLKLRRVLNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMANQDPESIMFN", "length": 758, "header": "tr|A0A5G2QZX7-1|A0A5G2QZX7_PIG Isoform 1 of Chloride channel protein OS=Sus scrofa OX=9823 GN=CLCN4 PE=1 SV=1 CANONICAL=A0A5G2QZX7-1" }, "locus": { "chromosome": "X", "start_pos": 7017731, "end_pos": 6977125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066570.1", "url": "https://www.ensembl.org/id/ENSSSCT00000066570.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069689.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069689.1" } ] } }, { "isoform_ac": "A0A5G2R2J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7/entry#A0A5G2R2J6-1", "sequence": { "sequence": "MVHAGVMSGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKSRDTDRHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFEDRDKCPLWQKWSELLVNQSEGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVSSAVSVCCRLLLSLEDLVAVLLRSPGGSLHAAVHQPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLRRKTTRLGKYPVLEVIAVTAITAIVAYPNPYTRRSTSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGVGVYTAMWQLALALIFKIVITIFTFGMKIPSGLFIPSMAVGAMAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEPPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSRDSERLIGFAQRRELILAIKNARQRQEGIVSDSVMYFTEEPPELPANSPHPLKLRRVLNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMANQDPESIMFN", "length": 727, "header": "tr|A0A5G2R2J6-1|A0A5G2R2J6_PIG Computationally mapped isoform of Chloride channel protein OS=Sus scrofa OX=9823 GN=CLCN4 PE=1 SV=2 CANONICAL=A0A5G2QZX7-1" }, "locus": { "chromosome": "X", "start_pos": 7017731, "end_pos": 6977125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072458.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072458.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068422.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068422.2" } ] } }, { "isoform_ac": "A0A8W4FGW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7/entry#A0A8W4FGW3-1", "sequence": { "sequence": "MVHAGVMSGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKSRDTDRHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFEDRDKCPLWQKWSELLVNQSENICLFWTFHGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSIPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGLFIRCNIAWCRRRKTTRLGKYPVLEVIAVTAITAIVAYPNPYTRRSTSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGVGVYTAMWQLALALIFKIVITIFTFGMKIPSGLFIPSMAVGAMAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEPPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSRDSERLIGFAQRRELILAIKNARQRQEGIVSDSVMYFTEEPPELPANSPHPLKLRRVLNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMANQDPESIMFN", "length": 767, "header": "tr|A0A8W4FGW3-1|A0A5G2QZX7_PIG Computationally mapped isoform of Chloride channel protein OS=Sus scrofa OX=9823 GN=CLCN4 PE=1 SV=1 CANONICAL=A0A5G2QZX7-1" }, "locus": { "chromosome": "X", "start_pos": 7017731, "end_pos": 6977125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104858.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104858.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077550.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077550.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 510, "start_aa": "Thr", "end_pos": 510, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr510", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FGW3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGW3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ], "pmid": "" }, { "name": "voltage-gated chloride channel activity", "id": "GO:0005247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005247", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZX7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 696, "end_pos": 698, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZX7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 758, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZX7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZX7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZX7" }, { "id": "PS51371", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51371" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBS", "eco_id": "ECO_0000259", "start_pos": 598, "end_pos": 664, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 510 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 141, "end_pos": 143 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 696, "end_pos": 698 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3A4-1", "uniprot_ac": "A0A5G2R3A4", "uniprot_id": "A0A5G2R3A4_PIG", "mass": { "chemical_mass": 11985.0, "monoisotopic_mass": 11985.0 }, "refseq": {}, "gene_names": [ { "name": "CISD1", "type": "recommended", "evidence": [ { "id": "A0A5G2R3A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4" } ] }, { "name": "UBE2D1", "type": "recommended", "evidence": [ { "id": "A0A5G2R3A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4" } ] }, { "name": "CISD1", "type": "synonym", "evidence": [ { "id": "A0A5G2R3A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4" } ] } ], "protein_names": [ { "name": "CDGSH iron sulfur domain 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R3A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UBE2D1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4", "locus": { "chromosome": "14", "start_pos": 92294642, "end_pos": 92330541, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000033323", "url": "https://www.ensembl.org/id/ENSSSCG00000033323" } ] } } ], "crossref": [ { "id": "A0A5G2R3A4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3A4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000033323", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033323", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR018967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13680", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13680", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13680:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13680:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09360", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09360", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10660", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10660", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R3A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0WFJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WFJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0WFJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WFJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GATAASLRQIEWIAAVTIAAGTAAIGYLAYKRFYVKDHRNKSMVNPHIQKDNPKVVHAFDMEDLGDKAVYCRCWRSKKFPLCDGSHIKHNEETGDNVGPLIIKKKDT", "length": 107, "header": "tr|A0A5G2R3A4-1|A0A5G2R3A4_PIG Isoform 1 of CDGSH iron sulfur domain 1 OS=Sus scrofa OX=9823 GN=UBE2D1 PE=4 SV=2 CANONICAL=A0A5G2R3A4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R3A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4/entry#A0A5G2R3A4-1", "sequence": { "sequence": "GATAASLRQIEWIAAVTIAAGTAAIGYLAYKRFYVKDHRNKSMVNPHIQKDNPKVVHAFDMEDLGDKAVYCRCWRSKKFPLCDGSHIKHNEETGDNVGPLIIKKKDT", "length": 107, "header": "tr|A0A5G2R3A4-1|A0A5G2R3A4_PIG Isoform 1 of CDGSH iron sulfur domain 1 OS=Sus scrofa OX=9823 GN=UBE2D1 PE=4 SV=2 CANONICAL=A0A5G2R3A4-1" }, "locus": { "chromosome": "14", "start_pos": 92373338, "end_pos": 92363827, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089285.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089285.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068672.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068672.2" } ] } }, { "isoform_ac": "A0A8D0WFJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4/entry#A0A8D0WFJ4-1", "sequence": { "sequence": "MQHSLLSRILWNWVEWIAAVTIAAGTAAIGYLAYKRFYVKDHRNKSMVNPHIQKDNPKVVHAFDMEDLGDKAVYCRCWRSKKFPLCDGSHIKHNEETGDNVGPLIIKKKDT", "length": 111, "header": "tr|A0A8D0WFJ4-1|A0A5G2R3A4_PIG Computationally mapped isoform of CDGSH iron sulfur domain 1 OS=Sus scrofa OX=9823 GN=UBE2D1 PE=4 SV=1 CANONICAL=A0A5G2R3A4-1" }, "locus": { "chromosome": "14", "start_pos": 92374380, "end_pos": 92363827, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064863.2", "url": "https://www.ensembl.org/id/ENSSSCT00000064863.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041408.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041408.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0WFJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WFJ4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4" } ], "pmid": "" }, { "name": "L-cysteine transaminase activity", "id": "GO:0047801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047801", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R3A4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 107, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R3A4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3A4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R3A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A4" }, { "id": "SM00704", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00704" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Iron-binding zinc finger CDGSH type", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 92, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1R6-1", "uniprot_ac": "A0A5G2R1R6", "uniprot_id": "A0A5G2R1R6_PIG", "mass": { "chemical_mass": 81376.0, "monoisotopic_mass": 81376.0 }, "refseq": {}, "gene_names": [ { "name": "APEH", "type": "recommended", "evidence": [ { "id": "A0A5G2R1R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6" } ] } ], "protein_names": [ { "name": "Acylamino-acid-releasing enzyme", "type": "recommended", "evidence": [ { "id": "A0A5G2R1R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.1", "type": "synonym", "evidence": [ { "id": "A0A5G2R1R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Aminopeptidase involved in the degradation of N(alpha)-acylated peptides. Displays exopeptidase activity toward N-formyl and N-acetyl peptides with a preference for dipeptide substrates. Catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. Hydrolyzes N-formylated peptides likely arising from N-terminal proteolytic cleavage of bacterial and mitochondrial proteins. May act sequentially with ACY1 in the degradation of N-acylated peptides: APEH first cleaves N-acylaminoacids from N-acylated peptides, then ACY1 further hydrolyzes the N-acylaminoacid into free aminoacid and a carboxylate. Displays endopeptidase activity involved in the degradation of oxidized and glycated proteins.", "evidence": [ { "database": "UniProtKB", "id": "F1SPS7", "url": "https://www.uniprot.org/uniprotkb/F1SPS7#function" }, { "database": "UniProtKB", "id": "ARBA00094309", "url": "https://www.uniprot.org/uniprotkb/ARBA00094309#function" }, { "database": "UniProtKB", "id": "I3LFX8", "url": "https://www.uniprot.org/uniprotkb/I3LFX8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1R6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "APEH", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6", "locus": { "chromosome": "13", "start_pos": 32214518, "end_pos": 32205609, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011385", "url": "https://www.ensembl.org/id/ENSSSCG00000011385" } ] } } ], "crossref": [ { "id": "A0A5G2R1R6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1R6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011385", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011385", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR42776", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42776", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42776:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42776:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19283", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19283", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72764", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72764", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "83443", "url": "https://www.rhea-db.org/rhea/83443", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83487", "url": "https://www.rhea-db.org/rhea/83487", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83491", "url": "https://www.rhea-db.org/rhea/83491", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83495", "url": "https://www.rhea-db.org/rhea/83495", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83499", "url": "https://www.rhea-db.org/rhea/83499", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83503", "url": "https://www.rhea-db.org/rhea/83503", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83507", "url": "https://www.rhea-db.org/rhea/83507", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83511", "url": "https://www.rhea-db.org/rhea/83511", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R1R6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FNE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FNE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FNE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SPS7", "url": "https://www.uniprot.org/uniprotkb/F1SPS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SPS7-1", "url": "https://www.uniprot.org/uniprotkb/F1SPS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LFX8", "url": "https://www.uniprot.org/uniprotkb/I3LFX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LFX8-1", "url": "https://www.uniprot.org/uniprotkb/I3LFX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RERTVLLSEPEEAAALYRGLSRQPALSAACLGPEVTTQYGGRYRTVHTEWTQRDLERMENIRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGGTGTAEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTKALDVTGSDDEMARTKKPDQAIKGDQFLFYEDWGENMVSKSTPVLCVLDIESGNISVLEGVPESVSPGQAFWAPGDTGVVFVGWWHEPFRLGIRFCTNRRLSMNPVLCRPHWGELLSDESVAVTSPRLSPDQCRIVYLRFPSLVPHQQCGQLCLYDWYTRVTSVVVDIVPRQLGEDFSGIYCSLLPLGCWSADSQRVVFDSPQRSRQDLFAVDTQMGSVTSLTAGGSGGSWKLLTIDRDLMVVQFSTPSVPPSLKVGFLPPAGKEQAVSWVSLEEAEPFPDISWSIRVLQPPPQQEHVQYAGLDFEAILLQPSNSPEKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDAGRVALMGGSHGGFLSCHLIGQYPETYSACVVRNPVINIASMMGSTDIPDWCMVEAGFSYSSDCLPDLSVWAAMLDKSPIKYAPQVKTPLLLMLGQEDRRVPFKQGMEYYRVLKARNVPVRLLLYPKSTHALSEVEVESDSFMNAVLWLCTHLGS", "length": 732, "header": "tr|A0A5G2R1R6-1|A0A5G2R1R6_PIG Isoform 1 of Acylamino-acid-releasing enzyme OS=Sus scrofa OX=9823 GN=APEH PE=3 SV=1 CANONICAL=A0A5G2R1R6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6/entry#A0A5G2R1R6-1", "sequence": { "sequence": "RERTVLLSEPEEAAALYRGLSRQPALSAACLGPEVTTQYGGRYRTVHTEWTQRDLERMENIRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGGTGTAEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTKALDVTGSDDEMARTKKPDQAIKGDQFLFYEDWGENMVSKSTPVLCVLDIESGNISVLEGVPESVSPGQAFWAPGDTGVVFVGWWHEPFRLGIRFCTNRRLSMNPVLCRPHWGELLSDESVAVTSPRLSPDQCRIVYLRFPSLVPHQQCGQLCLYDWYTRVTSVVVDIVPRQLGEDFSGIYCSLLPLGCWSADSQRVVFDSPQRSRQDLFAVDTQMGSVTSLTAGGSGGSWKLLTIDRDLMVVQFSTPSVPPSLKVGFLPPAGKEQAVSWVSLEEAEPFPDISWSIRVLQPPPQQEHVQYAGLDFEAILLQPSNSPEKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDAGRVALMGGSHGGFLSCHLIGQYPETYSACVVRNPVINIASMMGSTDIPDWCMVEAGFSYSSDCLPDLSVWAAMLDKSPIKYAPQVKTPLLLMLGQEDRRVPFKQGMEYYRVLKARNVPVRLLLYPKSTHALSEVEVESDSFMNAVLWLCTHLGS", "length": 732, "header": "tr|A0A5G2R1R6-1|A0A5G2R1R6_PIG Isoform 1 of Acylamino-acid-releasing enzyme OS=Sus scrofa OX=9823 GN=APEH PE=3 SV=1 CANONICAL=A0A5G2R1R6-1" }, "locus": { "chromosome": "13", "start_pos": 32214359, "end_pos": 32205609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066828.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066828.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071059.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071059.1" } ] } }, { "isoform_ac": "A0A8W4FNE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6/entry#A0A8W4FNE3-1", "sequence": { "sequence": "MERQVLLSEPEEAAALYRGLSRQPALSAACLGPEVTTQYGGRYRTVHTEWTQRDLERMENIRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGGTGTAEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTKALDVTGSDDEMARTKKPDQAIKGDQFLFYEDWGENMVSKSTPVLCVLDIESGNISVLEGVPESVSPGQAFWAPGDTGVVFVGWWHEPFRLGIRFCTNRRSALYYVDLTGGKCELLSDESVAVTSPRLSPDQCRIVYLRFPSLVPHQQCGQLCLYDWYTRVTSVVVDIVPRQLGEDFSGIYCSLLPLGCWSADSQRVVFDSPQRSRQDLFAVDTQMGSVTSLTAGGSGGSWKLLTIDRDLMVVQFSTPSVPPSLKVGFLPPAGKEQAVSWVSLEEAEPFPDISWSIRVLQPPPQQEHVQYAGLDFEAILLQPSNSPEKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQVHGGGWLLLQQRLPARPQCVGCDAGQVTHQVCPSGEDSTVTDARPGGQACALQAGHGVLPCSQGPECASPAPALSQKHPCTIRGGGGIRQLHECCALAMHTLGQLKPYLSA", "length": 675, "header": "tr|A0A8W4FNE3-1|A0A5G2R1R6_PIG Computationally mapped isoform of Acylamino-acid-releasing enzyme OS=Sus scrofa OX=9823 GN=APEH PE=3 SV=1 CANONICAL=A0A5G2R1R6-1" }, "locus": { "chromosome": "13", "start_pos": 32214379, "end_pos": 32205876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102828.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102828.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080423.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080423.1" } ] } }, { "isoform_ac": "F1SPS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6/entry#F1SPS7-1", "sequence": { "sequence": "MERQVLLSEPEEAAALYRGLSRQPALSAACLGPEVTTQYGGRYRTVHTEWTQRDLERMENIRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGGTGTAEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTKALDVTGSDDEMARTKKPDQAIKGDQFLFYEDWGENMVSKSTPVLCVLDIESGNISVLEGVPESVSPGQAFWAPGDTGVVFVGWWHEPFRLGIRFCTNRRSALYYVDLTGGKCELLSDESVAVTSPRLSPDQCRIVYLRFPSLVPHQQCGQLCLYDWYTRVTSVVVDIVPRQLGEDFSGIYCSLLPLGCWSADSQRVVFDSPQRSRQDLFAVDTQMGSVTSLTAGGSGGSWKLLTIDRDLMVVQFSTPSVPPSLKVGFLPPAGKEQAVSWVSLEEAEPFPDISWSIRVLQPPPQQEHVQYAGLDFEAILLQPSNSPEKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDAGRVALMGGSHGGFLSCHLIGQYPETYSACVVRNPVINIASMMGSTDIPDCSISYRCMVEAGFSYSSDCLPDLSVWAAMLDKSPIKYAPQVKTPLLLMLGQEDRRVPFKQGMEYYRVLKARNVPVRLLLYPKSTHALSEVEVESDSFMNAVLWLCTHLGS", "length": 737, "header": "tr|F1SPS7-1|F1SPS7_PIG Computationally mapped isoform of Acylamino-acid-releasing enzyme OS=Sus scrofa OX=9823 GN=APEH PE=3 SV=3 CANONICAL=A0A5G2R1R6-1" }, "locus": { "chromosome": "13", "start_pos": 32214359, "end_pos": 32205876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012463.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012463.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012138.3", "url": "https://www.ensembl.org/id/ENSSSCP00000012138.3" } ] } }, { "isoform_ac": "I3LFX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6/entry#I3LFX8-1", "sequence": { "sequence": "MERQVRDRPAVPVVFATRAVPDPAVSPAQVLLSEPEEAAALYRGLSRQPALSAACLGPEVTTQYGGRYRTVHTEWTQRDLERMENIRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGGTGTAEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTKALDVTGSDDEMARTKKPDQAIKGDQFLFYEDWGENMVSKSTPVLCVLDIESGNISVLEGVPESVSPGQAFWAPGDTGVVFVGWWHEPFRLGIRFCTNRRSALYYVDLTGGKCELLSDESVAVTSPRLSPDQCRIVYLRFPSLVPHQQCGQLCLYDWYTRVTSVVVDIVPRQLGEDFSGIYCSLLPLGCWSADSQRVVFDSPQRSRQDLFAVDTQMGSVTSLTAGGSGGSWKLLTIDRDLMVVQFSTPSVPPSLKVGFLPPAGKEQAVSWVSLEEAEPFPDISWSIRVLQPPPQQEHVQYAGLDFEAILLQPSNSPEKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDAGRVALMGGSHGGFLSCHLIGQYPETYSACVVRNPVINIASMMGSTDIPDWCMVEAGFSYSSDCLPDLSVWAAMLDKSPIKYAPQVKTPLLLMLGQEDRRVPFKQGMEYYRVLKARNVPVRLLLYPKSTHALSEVEVESDSFMNAVLWLCTHLGS", "length": 757, "header": "tr|I3LFX8-1|A0A5G2R1R6_PIG Computationally mapped isoform of Acylamino-acid-releasing enzyme OS=Sus scrofa OX=9823 GN=APEH PE=3 SV=2 CANONICAL=A0A5G2R1R6-1" }, "locus": { "chromosome": "13", "start_pos": 32214359, "end_pos": 32205876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023528.4", "url": "https://www.ensembl.org/id/ENSSSCT00000023528.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022971.2", "url": "https://www.ensembl.org/id/ENSSSCP00000022971.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LFX8", "url": "https://www.uniprot.org/uniprotkb/I3LFX8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-72764", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72764", "resource": "Reactome", "description": "Eukaryotic Translation Termination" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1R6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6" } ], "pmid": "" }, { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1R6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6" } ], "pmid": "" }, { "name": "omega peptidase activity", "id": "GO:0008242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008242", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1R6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1R6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1R6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1R6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1R6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6" } ], "pmid": "" }, { "name": "amyloid-beta metabolic process", "id": "GO:0050435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050435", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1R6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "83443", "name": "", "equation": "N(alpha)-formyl-L-methionyl-L-leucyl-L-phenylalanine + H2O = L-leucyl-L-phenylalanine + N(alpha)-formyl-L-methionine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83443", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83443" } ] }, { "id": "83487", "name": "", "equation": "N(alpha)-formyl-L-methionyl-L-phenylalanine + H2O = N(alpha)-formyl-L-methionine + L-phenylalanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83487", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83487" } ] }, { "id": "83491", "name": "", "equation": "N(alpha)-formyl-L-methionyl-L-alanine + H2O = N(alpha)-formyl-L-methionine + L-alanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83491", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83491" } ] }, { "id": "83495", "name": "", "equation": "N(alpha)-formyl-L-methionyl-L-alanyl-L-serine + H2O = L-alanyl-L-serine + N(alpha)-formyl-L-methionine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83495", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83495" } ] }, { "id": "83499", "name": "", "equation": "N(alpha)-formyl-L-methionyl-L-serine + H2O = N(alpha)-formyl-L-methionine + L-serine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83499", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83499" } ] }, { "id": "83503", "name": "", "equation": "N(alpha)-acetyl-L-methionyl-L-alanyl-L-serine + H2O = L-alanyl-L-serine + N-acetyl-L-methionine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83503", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83503" } ] }, { "id": "83507", "name": "", "equation": "N(alpha)-acetyl-L-alanyl-L-alanine + H2O = N(alpha)-acetyl-L-alanine + L-alanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83507", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83507" } ] }, { "id": "83511", "name": "", "equation": "N(alpha)-acetyl-L-alanyl-L-alanyl-L-alanine + H2O = N(alpha)-acetyl-L-alanine + L-alanyl-L-alanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83511", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83511" } ] }, { "id": "R-SSC-5691512", "name": "APEH hydrolyses NAc-Ser-protein", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-5691517", "R-ALL-6785226" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5691512", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5691512" } ] }, { "id": "R-SSC-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6800434" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5691517", "participant_name": "NAc-Ser residue [cytosol]", "crossref": [ { "id": "83690", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6785226", "participant_name": "protein [cytosol]", "crossref": [ { "id": "36080", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1R6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 732, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1R6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1R6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6" }, { "id": "PF19283", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19283" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Acylamino-acid-releasing enzyme N-terminal", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 458, "start_aa": "Thr", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R1R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R6" }, { "id": "PF00326", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S9 prolyl oligopeptidase catalytic", "eco_id": "ECO_0000259", "start_pos": 523, "end_pos": 731, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 233, "end_pos": 235 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R356-1", "uniprot_ac": "A0A5G2R356", "uniprot_id": "A0A5G2R356_PIG", "mass": { "chemical_mass": 48045.0, "monoisotopic_mass": 48045.0 }, "refseq": { "ac": "XP_005665941", "name": "tapasin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665941" }, "gene_names": [ { "name": "TAPBP", "type": "recommended", "evidence": [ { "id": "A0A5G2R356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ] }, { "name": "TAPBP", "type": "synonym", "evidence": [ { "id": "XP_005665941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665941" } ] } ], "protein_names": [ { "name": "Tapasin", "type": "recommended", "evidence": [ { "id": "A0A5G2R356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356/entry#names_and_taxonomy" } ] }, { "name": "TAP-binding protein", "type": "synonym", "evidence": [ { "id": "A0A5G2R356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356/entry#names_and_taxonomy" } ] }, { "name": "tapasin", "type": "synonym", "evidence": [ { "id": "XP_005665941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665941" } ] } ], "function": [ { "annotation": "Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1Y1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1Y1#function" }, { "database": "UniProtKB", "id": "ARBA00037757", "url": "https://www.uniprot.org/uniprotkb/ARBA00037757#function" }, { "database": "UniProtKB", "id": "A0A5G2R585", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R585#function" }, { "database": "UniProtKB", "id": "A0A8D1NLX3", "url": "https://www.uniprot.org/uniprotkb/A0A8D1NLX3#function" }, { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TAPBP", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356", "locus": { "chromosome": "7", "start_pos": 29663495, "end_pos": 29673634, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001507", "url": "https://www.ensembl.org/id/ENSSSCG00000001507" } ] } } ], "crossref": [ { "id": "A0A5G2R356", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R356", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001507", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001507", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100155428", "url": "https://www.ncbi.nlm.nih.gov/gene/100155428", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155428", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155428", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMPPTLE", "url": "https://omabrowser.org/oma/group/YMPPTLE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R356", "url": "https://www.orthodb.org/?gene=A0A5G2R356", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23411", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23411", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-983170", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005665941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665941", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A1Y1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R356-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R585", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R585", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R585-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R585-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1NLX3", "url": "https://www.uniprot.org/uniprotkb/A0A8D1NLX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1NLX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1NLX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPLSLLLSVVALGLASTVSAGPAVIECWFVEDAGRGQLSKKPAALLLRQGPGSPPPRPDLEPELYLKVHDPAGALLAAFRQYPRDAPAPRCEMSHYIPLPASPDWVSGLTPEQRCPRALDGKWLMVSMSSPVLSLSSFLQPQSEPQLEPALITMATAVLTVITHTPAPRIRLGQDALLDLSFAYVPPTSKAAISLAPGPPPFGLEWRRQHLGKGHLLLAATPGLSGQVPAAREGAVAFAAWDDDEPWGPWTGNGSFWLPAVQPFQEGTYLATVHLPYLQGQVAMDLAVQKSPKVSLTPAPLVWAAPGEAPPELLCLVSHFYPSEGLEVEWELRGGPQGRFQKAEGQSWHSALSHHADGSVSLSAHLQLPPVTTEQHGARYACRVHHPSLPALGRRSEITLQVAGLSGPSLEDGVGLFLSAFLLLGLIKALGWAAAHLAASRDSTQKKTE", "length": 450, "header": "tr|A0A5G2R356-1|A0A5G2R356_PIG Isoform 1 of Tapasin OS=Sus scrofa OX=9823 GN=TAPBP PE=1 SV=2 CANONICAL=A0A5G2R356-1" }, "isoforms": [ { "isoform_ac": "A0A287A1Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356/entry#A0A287A1Y1-1", "sequence": { "sequence": "MKPLSLLLSVVALGLASTVSAGPAVIECWFVEDAGRGQLSKKPAALLLRQGPGSPPPRPDLEPELYLKVHDPAGALLAAFRQYPRDAPAPRCEMSHYIPLPASPDWVSGLTPEQRCPRALDGKWLMVSMSSPVLSLSSFLQPQSEPQLEPALITMATAVLTVITHTPAPRIRLGQDALLDLSFAYVPPTSKAAISLAPGPPPFGLEWRRQHLGKGHLLLAATPGLSGQVPAAREGAVAFAAWDDDEPWGPWTGNGSFWLPAVQPFQEGTYLATVHLPYLQGQVAMDLAVQKSPKVSLTPAPLVWAAPGEAPPELLCLVSHFYPSEGLEVEWELRGGPQGRFQKAEGQSWHSALSHHADGSVSLSAHLQLPPVTTEQHGARYACRVHHPSLPALGRRSEITLQVAGLSGPSLEDGVGLFLSAFLLLGLIKALGWAAAHLAASRDSTQKVTVLLPHLSLLVVSPPPTPHSRARPQAWWASQGLGIHTDLSNPATKNILHLLPWV", "length": 502, "header": "tr|A0A287A1Y1-1|A0A5G2R356_PIG Computationally mapped isoform of Tapasin OS=Sus scrofa OX=9823 GN=TAPBP PE=1 SV=3 CANONICAL=A0A5G2R356-1" }, "locus": { "chromosome": "7", "start_pos": 29672642, "end_pos": 29665791, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053102.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053102.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037938.3", "url": "https://www.ensembl.org/id/ENSSSCP00000037938.3" } ] } }, { "isoform_ac": "A0A5G2R356-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356/entry#A0A5G2R356-1", "sequence": { "sequence": "MKPLSLLLSVVALGLASTVSAGPAVIECWFVEDAGRGQLSKKPAALLLRQGPGSPPPRPDLEPELYLKVHDPAGALLAAFRQYPRDAPAPRCEMSHYIPLPASPDWVSGLTPEQRCPRALDGKWLMVSMSSPVLSLSSFLQPQSEPQLEPALITMATAVLTVITHTPAPRIRLGQDALLDLSFAYVPPTSKAAISLAPGPPPFGLEWRRQHLGKGHLLLAATPGLSGQVPAAREGAVAFAAWDDDEPWGPWTGNGSFWLPAVQPFQEGTYLATVHLPYLQGQVAMDLAVQKSPKVSLTPAPLVWAAPGEAPPELLCLVSHFYPSEGLEVEWELRGGPQGRFQKAEGQSWHSALSHHADGSVSLSAHLQLPPVTTEQHGARYACRVHHPSLPALGRRSEITLQVAGLSGPSLEDGVGLFLSAFLLLGLIKALGWAAAHLAASRDSTQKKTE", "length": 450, "header": "tr|A0A5G2R356-1|A0A5G2R356_PIG Isoform 1 of Tapasin OS=Sus scrofa OX=9823 GN=TAPBP PE=1 SV=2 CANONICAL=A0A5G2R356-1" }, "locus": { "chromosome": "7", "start_pos": 29672642, "end_pos": 29664807, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067132.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067132.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070782.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070782.2" } ] } }, { "isoform_ac": "A0A5G2R585-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356/entry#A0A5G2R585-1", "sequence": { "sequence": "MKPLSLLLSVVALGLASTVSAGPAVIECWFVEDAGRGQLSKKPAALLLRQGPGSPPPRPDLEPELYLKVHAVLTVITHTPAPRIRLGQDALLDLSFAYVPPTSKAAISLAPGPPPFGLEWRRQHLGKGHLLLAATPGLSGQVPAAREGAVAFAAWDDDEPWGPWTGNGSFWLPAVQPFQEGTYLATVHLPYLQGQVAMDLAVQKSPKVSLTPAPLVWAAPGEAPPELLCLVSHFYPSEGLEVEWELRGGPQGRFQKAEGQSWHSALSHHADGSVSLSAHLQLPPVTTEQHGARYACRVHHPSLPALGRRSEITLQVAGLSGPSLEDGVGLFLSAFLLLGLIKALGWAAAHLAASRDSTQKVTVLLPHLSLLVVSPPPTPHSRARPQAWWASQGLGIHTDLSNPATKNILHLLPWV", "length": 415, "header": "tr|A0A5G2R585-1|A0A5G2R356_PIG Computationally mapped isoform of Tapasin OS=Sus scrofa OX=9823 GN=TAPBP PE=1 SV=2 CANONICAL=A0A5G2R356-1" }, "locus": { "chromosome": "7", "start_pos": 29672642, "end_pos": 29665791, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070680.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070680.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072252.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072252.2" } ] } }, { "isoform_ac": "A0A8D1NLX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356/entry#A0A8D1NLX3-1", "sequence": { "sequence": "MKPLSLLLSVVALGLASTVSAGPAVIECWFVEDAGRGQLSKKPAALLLRQGPGSPPPRPDLEPELYLKVHDPAGALLAAFRQYPRDAPAPRCEMSHYIPLPASPDWVSGLTPEQRCPRALDGKWLMVSMSSPVLSLSSFLQPQSEPQLEPALITMATAVLTVITHTPAPRIRLGQDALLDLSFAYVPPTSKAAISLAPGPPPFGLEWRRQHLGKGHLLLAATPGLSGQVPAAREGAVAFAAWDDDEPWGPWTGNGSFWLPAVQPFQEGTYLATVHLPYLQGQVAMDLAVQKSPKVSLTPAPLVWAAPGEAPPELLCLVSHFYPSEGLEVEWELRGGPQGRFQKAEGQSWHSALSHHADGSVSLSAHLQLPPVTTEQHGARYACRVHHPSLPALGRRSEITLQVAGLSGPSLEDGVGLFLSAFLLLGLIKALGWAAAHLAASRDSTQKPSSHCSSHRRRILSNNSLPPSLDSRVPALLLGSPSPSLVSRIIACSPTVPLLCGCPRLH", "length": 506, "header": "tr|A0A8D1NLX3-1|A0A5G2R356_PIG Computationally mapped isoform of Tapasin OS=Sus scrofa OX=9823 GN=TAPBP PE=1 SV=1 CANONICAL=A0A5G2R356-1" }, "locus": { "chromosome": "7", "start_pos": 29672642, "end_pos": 29663795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001680.3", "url": "https://www.ensembl.org/id/ENSSSCT00000001680.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001636.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001636.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1Y1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1Y1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155428", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155428", "resource": "KEGG Pathway" }, { "id": "R-SSC-983170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983170", "resource": "Reactome", "description": "Antigen Presentation: Folding, assembly and peptide loading of class I MHC" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LGP5-1", "protein_name": "TAP binding protein", "gene_name": "Tapbp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEKANQGLTQGYLTNPGPEEEGGASGVLSYAGKRAVRSRERANVQGSGWSLRSGSQYWSMGKGLATVVVSAGPQTIECWFVEDAGGGGLSKKPATLLLRHGPRGPPPRPDLDPKLYFKVDDPAGMLLAAFRRYPAGAHAPHCEMSSYIPFPASAKWARGLSPQQNCSRALDGDWLMVSVSGTVFSLSSLLRPLPEPQREPVFITMATVVLTVLTRHPAPRIHLGKDAVLDLRFAYAPPALEDAPSVASGPPPFGLEWRRQHRGKGHLLLAAIPGLLEKMPPAREKAVAFAAWDDDNDPWGPWTGNGTLWLPAVSPSQEGVYLATVHLPYLQGQVSLELTVHKPPRVSLTPAPIVWAAPGEAPPELLCLVSHFYPEEGLEVEWELRGGPEGSSRKAEGKTWVSTVRHHSDGSVSQSGHLQLPPVTDKQHGVRYACRVRHPSLPSSGRSAEVTLEVAGFSGPSIEDGIGLFLSAFLLLGLFKALGWMAAYLTIPKILKEKASATSLTVPKDEKKSE", "length": 515 }, "evidence": [ { "id": "A0A5G2R356", "url": "https://omabrowser.org/oma/group/A0A5G2R356/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15533-1", "protein_name": "Tapasin", "gene_name": "TAPBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDLDPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALDGAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDLSFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAAWDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPSLPASGRSAEVTLEVAGLSGPSLEDSVGLFLSAFLLLGLFKALGWAAVYLSTCKDSKKKAE", "length": 448 }, "evidence": [ { "id": "A0A5G2R356", "url": "https://omabrowser.org/oma/group/A0A5G2R356/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R233-1", "protein_name": "Tapasin", "gene_name": "Tapbp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPLLLLVAVALGLATVVSVVSAGPEAIECWFVEDAGGGGLSKKPATLLLRHGPRGPPPRPDLDPKLYFKVDDPAGMLLAAFRRYPAGASAPHCEMSRFIPFPASAKWARSLSPEQNCPRALDGDWLLVSVSSTLFSLSSLLRPQPEPLREPVVITMATVVLTVLTHNPAPRVQLGKDAVLDLRFAYAPSALEGSPSLDAGPPPFGLEWRRQHRGKGHLLLAATPGLAGRMPPAQEKATAFAAWDDDEPWGPWTGNGTFWLPAVKPSQEGVYLATVHLPYLQGQVSLELTVHKAPRVSLTPAPVVWAAPGEAPPELLCLASHFFPAEGLEVKWELRGGPGGSSRKVEGKTWLSTIRHHSDGSVSQSGHLQLPPVTAKQHGVHYVCRVYHSSLPASGRSADVTLEVAGFSGPSIEDGIGLFLSAFLLLGLLKVLGWLAAYWTIPEVSKEKATAASLTIPRNSKKSQ", "length": 465 }, "evidence": [ { "id": "A0A5G2R356", "url": "https://omabrowser.org/oma/group/A0A5G2R356/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "MHC class I peptide loading complex", "id": "GO:0042824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042824", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "peptide antigen binding", "id": "GO:0042605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042605", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "TAP1 binding", "id": "GO:0046978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "TAP2 binding", "id": "GO:0046979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046979", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "MHC class I protein complex binding", "id": "GO:0023024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023024", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "TAP complex binding", "id": "GO:0062061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062061", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "antigen processing and presentation of endogenous peptide antigen via MHC class I", "id": "GO:0019885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019885", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "antigen processing and presentation of peptide antigen via MHC class I", "id": "GO:0002474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002474", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "regulation of protein complex stability", "id": "GO:0061635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061635", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "peptide antigen assembly with MHC class I protein complex", "id": "GO:0002502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002502", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" }, { "name": "MHC class Ib protein complex assembly", "id": "GO:0002398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002398", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R356", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R356-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 450, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R356-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R356" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R356" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 293, "end_pos": 400, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 254, "end_pos": 256 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R4J6-1", "uniprot_ac": "A0A5G2R4J6", "uniprot_id": "A0A5G2R4J6_PIG", "mass": { "chemical_mass": 55602.0, "monoisotopic_mass": 55602.0 }, "refseq": {}, "gene_names": [ { "name": "CAMK2D", "type": "recommended", "evidence": [ { "id": "A0A5G2R4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ] } ], "protein_names": [ { "name": "calcium/calmodulin-dependent protein kinase", "type": "recommended", "evidence": [ { "id": "A0A5G2R4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.17", "type": "synonym", "evidence": [ { "id": "A0A5G2R4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CAMK2D", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6", "locus": { "chromosome": "8", "start_pos": 109222905, "end_pos": 108915572, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009123", "url": "https://www.ensembl.org/id/ENSSSCG00000009123" } ] } } ], "crossref": [ { "id": "A0A5G2R4J6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4J6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009123", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009123", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08332", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08332", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AHX0", "url": "https://www.uniprot.org/uniprotkb/A0A287AHX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AHX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AHX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2C9F383", "url": "https://www.uniprot.org/uniprotkb/A0A2C9F383", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2C9F383-1", "url": "https://www.uniprot.org/uniprotkb/A0A2C9F383-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ20", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ20-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS23", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS23-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUE4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R491", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R491", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R491-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R491-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK", "length": 491, "header": "tr|A0A5G2R4J6-1|A0A5G2R4J6_PIG Isoform 1 of calcium/calmodulin-dependent protein kinase OS=Sus scrofa OX=9823 GN=CAMK2D PE=3 SV=1 CANONICAL=A0A5G2R4J6-1" }, "isoforms": [ { "isoform_ac": "A0A287AHX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6/entry#A0A287AHX0-1", "sequence": { "sequence": "MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIN", "length": 477, "header": "tr|A0A287AHX0-1|A0A5G2R4J6_PIG Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Sus scrofa OX=9823 GN=CAMK2D PE=3 SV=2 CANONICAL=A0A5G2R4J6-1" }, "locus": { "chromosome": "8", "start_pos": 109220893, "end_pos": 108916356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049835.2", "url": "https://www.ensembl.org/id/ENSSSCT00000049835.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043591.2", "url": "https://www.ensembl.org/id/ENSSSCP00000043591.2" } ] } }, { "isoform_ac": "A0A2C9F383-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6/entry#A0A2C9F383-1", "sequence": { "sequence": "MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKVRNVTFPAEEFCMIYTSLTNFLRERKVKLLFATLKVFSSQQESTESSNTTIEDEDVKGMIKSEVENPDSEMYCFYFPYRKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK", "length": 488, "header": "tr|A0A2C9F383-1|A0A5G2R4J6_PIG Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Sus scrofa OX=9823 GN=CAMK2D PE=3 SV=3 CANONICAL=A0A5G2R4J6-1" }, "locus": { "chromosome": "8", "start_pos": 109217583, "end_pos": 108916356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009990.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009990.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009730.5", "url": "https://www.ensembl.org/id/ENSSSCP00000009730.5" } ] } }, { "isoform_ac": "A0A5G2QQ20-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6/entry#A0A5G2QQ20-1", "sequence": { "sequence": "MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKVRNVTFLTSLKLLSLFSCVSWLTLSLTLVENVLTNANCFFLYFVLTQEPQTTVIHNPDGNKVFRKNQHHPQEIIKVTEQLIEAINNGTLKKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK", "length": 499, "header": "tr|A0A5G2QQ20-1|A0A5G2R4J6_PIG Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Sus scrofa OX=9823 GN=CAMK2D PE=3 SV=2 CANONICAL=A0A5G2R4J6-1" }, "locus": { "chromosome": "8", "start_pos": 109217583, "end_pos": 108916356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073383.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073383.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064164.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064164.2" } ] } }, { "isoform_ac": "A0A5G2QS23-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6/entry#A0A5G2QS23-1", "sequence": { "sequence": "MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKVRNVTFSNILYDSYLLFSPYSFSSPLARKQEIIKVTEQLIEAINNGTLKKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK", "length": 458, "header": "tr|A0A5G2QS23-1|A0A5G2R4J6_PIG Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Sus scrofa OX=9823 GN=CAMK2D PE=3 SV=1 CANONICAL=A0A5G2R4J6-1" }, "locus": { "chromosome": "8", "start_pos": 109217583, "end_pos": 108916356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070379.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070379.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067592.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067592.1" } ] } }, { "isoform_ac": "A0A5G2QUE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6/entry#A0A5G2QUE4-1", "sequence": { "sequence": "MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKVRNVTFARDHTPPRGTQTTPPTGSNILYDSYLLFSPYSFSSPLARKQEIIKVTEQLIEAINNGTLKKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK", "length": 475, "header": "tr|A0A5G2QUE4-1|A0A5G2R4J6_PIG Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Sus scrofa OX=9823 GN=CAMK2D PE=3 SV=2 CANONICAL=A0A5G2R4J6-1" }, "locus": { "chromosome": "8", "start_pos": 109217583, "end_pos": 108916356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088894.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088894.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061781.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061781.2" } ] } }, { "isoform_ac": "A0A5G2R491-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6/entry#A0A5G2R491-1", "sequence": { "sequence": "MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICVSDIKLLFATLKVFSSQQESTESSNTTIEDEDVKGMIKSESNILYDSYLLFSPYSFSSPLARKQEIIKVTEQLIEAINNGTLKKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK", "length": 464, "header": "tr|A0A5G2R491-1|A0A5G2R491_PIG Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Sus scrofa OX=9823 GN=CAMK2D PE=3 SV=2 CANONICAL=A0A5G2R4J6-1" }, "locus": { "chromosome": "8", "start_pos": 109217583, "end_pos": 108916356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087473.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087473.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071153.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071153.2" } ] } }, { "isoform_ac": "A0A5G2R4J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6/entry#A0A5G2R4J6-1", "sequence": { "sequence": "MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK", "length": 491, "header": "tr|A0A5G2R4J6-1|A0A5G2R4J6_PIG Isoform 1 of calcium/calmodulin-dependent protein kinase OS=Sus scrofa OX=9823 GN=CAMK2D PE=3 SV=1 CANONICAL=A0A5G2R4J6-1" }, "locus": { "chromosome": "8", "start_pos": 109217583, "end_pos": 108916356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074642.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074642.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069110.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069110.1" } ] } }, { "isoform_ac": "A0A5G2RCS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6/entry#A0A5G2RCS0-1", "sequence": { "sequence": "MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKINNKANVVTSPKENIPTPALEPQTTVIHNPDGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIKPSCIPNGKENFSGSTSLWQNI", "length": 532, "header": "tr|A0A5G2RCS0-1|A0A5G2R4J6_PIG Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Sus scrofa OX=9823 GN=CAMK2D PE=3 SV=1 CANONICAL=A0A5G2R4J6-1" }, "locus": { "chromosome": "8", "start_pos": 109219480, "end_pos": 108916356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078069.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078069.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072072.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072072.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 177, "start_aa": "Thr", "end_pos": 177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr177", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCS0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" }, { "name": "calcium/calmodulin-dependent protein kinase activity", "id": "GO:0004683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004683", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" }, { "name": "cell communication", "id": "GO:0007154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007154", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" }, { "name": "signaling", "id": "GO:0023052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023052", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" }, { "name": "regulation of protein localization to plasma membrane", "id": "GO:1903076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903076", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" }, { "name": "regulation of neuronal synaptic plasticity", "id": "GO:0048168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048168", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R4J6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 491, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R4J6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4J6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J6" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 272, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 177 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 313, "end_pos": 315 }, { "start_pos": 349, "end_pos": 351 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R053-1", "uniprot_ac": "A0A5G2R053", "uniprot_id": "A0A5G2R053_PIG", "mass": { "chemical_mass": 38299.0, "monoisotopic_mass": 38299.0 }, "refseq": {}, "gene_names": [ { "name": "GALM", "type": "recommended", "evidence": [ { "id": "A0A5G2R053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053" } ] } ], "protein_names": [ { "name": "Galactose mutarotase", "type": "recommended", "evidence": [ { "id": "A0A5G2R053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053/entry#names_and_taxonomy" } ] }, { "name": "5.1.3.3", "type": "synonym", "evidence": [ { "id": "A0A5G2R053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053/entry#names_and_taxonomy" } ] }, { "name": "Aldose 1-epimerase", "type": "synonym", "evidence": [ { "id": "A0A5G2R053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism. Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1. Also active on D-glucose although shows a preference for galactose over glucose.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1AHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8D1AHN7#function" }, { "database": "UniProtKB", "id": "ARBA00045743", "url": "https://www.uniprot.org/uniprotkb/ARBA00045743#function" }, { "database": "UniProtKB", "id": "A0A5G2R1N9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1N9#function" }, { "database": "UniProtKB", "id": "A0A5G2QZ46", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ46#function" }, { "database": "UniProtKB", "id": "A0A5G2R053", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053#function" }, { "database": "UniProtKB", "id": "A0A4X1SZM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R053", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GALM", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053", "locus": { "chromosome": "3", "start_pos": 101617526, "end_pos": 101753125, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008486", "url": "https://www.ensembl.org/id/ENSSSCG00000008486" } ] } } ], "crossref": [ { "id": "A0A5G2R053", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R053", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008486", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008486", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09019", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09019", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR008183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10091", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10091", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10091:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10091:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01263", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01263", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "10264", "url": "https://www.rhea-db.org/rhea/10264", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "28675", "url": "https://www.rhea-db.org/rhea/28675", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SZM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SZM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ46", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ46-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R053", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R053-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1N9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1AHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8D1AHN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1AHN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1AHN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PCPSPSPVNFCRSRFGGGSSRDLEQLHTPSFPNGFSYKIRVWRPPLGGRDGGKVPAAIRPAESGHHLLGLHQKHPYFGAVVGRVANRIAKGTFTLDGKEYKLAINNGPNSLHGGVRGFDKVLWTPRVLSNGIEFSRVSPDGEEGYPGELKVWVTYTLDGGELVVNYRAQASQTTPVNLTNHSYFNLAGQGSPNIYDHEVTIEADAFLPVDETLIPTGEIAPVQGTAFDLRKPVELGKHLQEFHINGFDHNFCLKRSKEKQFCARVHHAGSGRVLEVYTTQPGIQFYTGNFLDGTLKGKTGAVYPKHSGFCLETQNWPNAVNQPHFPPVLLKPGAGWEPLQEPVSCAEIR", "length": 349, "header": "tr|A0A5G2R053-1|A0A5G2R053_PIG Isoform 1 of Galactose mutarotase OS=Sus scrofa OX=9823 GN=GALM PE=3 SV=2 CANONICAL=A0A5G2R053-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SZM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053/entry#A0A4X1SZM2-1", "sequence": { "sequence": "MVSVTRSVFGDLPSGAGTVEKFQLQSDQLRVDIISWGCTITALEVKDRQGRASDVVLGFAELKGEIAPVQGTAFDLRKPVELGKHLQEFHINGFDHNFCLKRSKEKQFCARVHHAGSGRVLEVYTTQPGIQFYTGNFLDGTLKGKTGAVYPKHSGFCLETQNWPNAVNQPHFPPVLLKPGEEYNHTTWFVFSVA", "length": 194, "header": "tr|A0A4X1SZM2-1|A0A4X1SZM2_PIG Computationally mapped isoform of Galactose mutarotase OS=Sus scrofa OX=9823 GN=GALM PE=4 SV=1 CANONICAL=A0A5G2R053-1" }, "locus": { "chromosome": "3", "start_pos": 101682765, "end_pos": 101618605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077149.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077149.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063869.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063869.1" } ] } }, { "isoform_ac": "A0A5G2QZ46-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053/entry#A0A5G2QZ46-1", "sequence": { "sequence": "MVSVTRSVFGDLPSGAGTVEKFQLQSDQLRVDIISWGCTITALEVKDRQGRASDVVLGFAELKEYLQKHPYFGAVVGRVANRIAKGTFTLDGKEYKLAINNGPNSLHGGVRGFDKVLWTPRVLSNGIEFSRVSPDGEEGYPGELKVWVTYTLDGGELVVNYRAQASQTTPVNLTNHSYFNLAGQGSPNIYDHEVTIEADAFLPVDETLIPTGEIAPVQGTAFDLRKPVELGKHLQEFHINGFDHNFCLKRSKEKQFCARAIYYCHKGPATTSHVFSNSIPQVNLSPLAPTMPLFLCPCLASCLSLLPLSPSLPVL", "length": 315, "header": "tr|A0A5G2QZ46-1|A0A5G2QZ46_PIG Computationally mapped isoform of Galactose mutarotase OS=Sus scrofa OX=9823 GN=GALM PE=3 SV=1 CANONICAL=A0A5G2R053-1" }, "locus": { "chromosome": "3", "start_pos": 101682765, "end_pos": 101621331, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066917.1", "url": "https://www.ensembl.org/id/ENSSSCT00000066917.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063510.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063510.1" } ] } }, { "isoform_ac": "A0A5G2R053-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053/entry#A0A5G2R053-1", "sequence": { "sequence": "PCPSPSPVNFCRSRFGGGSSRDLEQLHTPSFPNGFSYKIRVWRPPLGGRDGGKVPAAIRPAESGHHLLGLHQKHPYFGAVVGRVANRIAKGTFTLDGKEYKLAINNGPNSLHGGVRGFDKVLWTPRVLSNGIEFSRVSPDGEEGYPGELKVWVTYTLDGGELVVNYRAQASQTTPVNLTNHSYFNLAGQGSPNIYDHEVTIEADAFLPVDETLIPTGEIAPVQGTAFDLRKPVELGKHLQEFHINGFDHNFCLKRSKEKQFCARVHHAGSGRVLEVYTTQPGIQFYTGNFLDGTLKGKTGAVYPKHSGFCLETQNWPNAVNQPHFPPVLLKPGAGWEPLQEPVSCAEIR", "length": 349, "header": "tr|A0A5G2R053-1|A0A5G2R053_PIG Isoform 1 of Galactose mutarotase OS=Sus scrofa OX=9823 GN=GALM PE=3 SV=2 CANONICAL=A0A5G2R053-1" }, "locus": { "chromosome": "3", "start_pos": 101682862, "end_pos": 101618524, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089154.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089154.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067576.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067576.2" } ] } }, { "isoform_ac": "A0A5G2R1N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053/entry#A0A5G2R1N9-1", "sequence": { "sequence": "THLRVDIISWGCTITALEVKDRQGRASDVVLGFAELKEYLQKHPYFGAVVGRVANRIAKGTFTLDGKEYKLAINNGPNSLHGGVRGFDKVLWTPRVLSNGIEFSRVSPDGEEGYPGELKVWVTYTLDGGELVVNYRAQASQTTPVNLTNHSYFNLAGQGSPNIYDHEVTIEADAFLPVDETLIPTGEIAPVQGTAFDLRKPVELGKHLQEFHINGFDHNFCLKRSKEKQFCARVHHAGSGRVLEVYTTQPGIQFYTGNFLDGTLKGKTGAVYPKHSGFCLETQNWPNAVNQPHFPPVLLKPGEEYNHTTWFVFSVA", "length": 316, "header": "tr|A0A5G2R1N9-1|A0A5G2R053_PIG Computationally mapped isoform of Galactose mutarotase OS=Sus scrofa OX=9823 GN=GALM PE=3 SV=1 CANONICAL=A0A5G2R053-1" }, "locus": { "chromosome": "3", "start_pos": 101698468, "end_pos": 101618605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068895.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068895.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070265.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070265.1" } ] } }, { "isoform_ac": "A0A8D1AHN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053/entry#A0A8D1AHN7-1", "sequence": { "sequence": "MVSVTRSVFGDLPSGAGTVEKFQLQSDVVLGFAELKEYLQKHPYFGAVVGRVANRIAKGTFTLDGKEYKLAINNGPNSLHGGVRGFDKVLWTPRVLSNGIEFSRVSPDGEEGYPGELKVWVTYTLDGGELVVNYRAQASQTTPVNLTNHSYFNLAGQGSPNIYDHEVTIEADAFLPVDETLIPTGEIAPVQGTAFDLRKPVELGKHLQEFHINGFDHNFCLKRSKEKQFCARVHHAGSGRVLEVYTTQPGIQFYTGNFLDGTLKGKTGAVYPKHSGFCLETQNWPNAVNQPHFPPVLLKPGEEYNHTTWFVFSVA", "length": 315, "header": "tr|A0A8D1AHN7-1|A0A5G2R053_PIG Computationally mapped isoform of Galactose mutarotase OS=Sus scrofa OX=9823 GN=GALM PE=3 SV=1 CANONICAL=A0A5G2R053-1" }, "locus": { "chromosome": "3", "start_pos": 101682765, "end_pos": 101618605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009288.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009288.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009052.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009052.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1N9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1N9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R053", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R053", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053" } ], "pmid": "" }, { "name": "aldose 1-epimerase activity", "id": "GO:0004034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004034", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R053", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "galactose metabolic process", "id": "GO:0006012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006012", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R053", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053" } ], "pmid": "" }, { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R053", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053" } ], "pmid": "" }, { "name": "galactose catabolic process via UDP-galactose, Leloir pathway", "id": "GO:0033499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033499", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R053", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R053" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10264", "name": "", "equation": "alpha-D-glucose = beta-D-glucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10264", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10264" } ] }, { "id": "28675", "name": "", "equation": "alpha-D-galactose = beta-D-galactose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "28675", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/28675" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R053-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 349, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R053-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R053" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 180, "end_pos": 182 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R5V9-1", "uniprot_ac": "A0A5G2R5V9", "uniprot_id": "A0A5G2R5V9_PIG", "mass": { "chemical_mass": 60266.0, "monoisotopic_mass": 60266.0 }, "refseq": { "ac": "XP_003359435", "name": "RNA polymerase II-associated factor 1 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003359435" }, "gene_names": [ { "name": "PAF1", "type": "recommended", "evidence": [ { "id": "A0A5G2R5V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ] }, { "name": "PAF1", "type": "synonym", "evidence": [ { "id": "XP_003359435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003359435" } ] } ], "protein_names": [ { "name": "RNA polymerase II-associated factor 1 homolog", "type": "recommended", "evidence": [ { "id": "A0A5G2R5V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9/entry#names_and_taxonomy" } ] }, { "name": "RNA polymerase II-associated factor 1 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003359435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003359435" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PAF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9", "locus": { "chromosome": "6", "start_pos": 48046502, "end_pos": 48052038, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000022442", "url": "https://www.ensembl.org/id/ENSSSCG00000022442" } ] } } ], "crossref": [ { "id": "ENSSSCG00000022442", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022442", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100514194", "url": "https://www.ncbi.nlm.nih.gov/gene/100514194", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514194", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514194", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LVCRIKY", "url": "https://omabrowser.org/oma/group/LVCRIKY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QQP9", "url": "https://www.orthodb.org/?gene=A0A5G2QQP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R5V9", "url": "https://www.orthodb.org/?gene=A0A5G2R5V9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23188:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23188:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03985", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03985", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-112382", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112382", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-75955", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8866654", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8866654", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003359435", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003359435", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QQP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R544", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R544", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R544-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R544-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SEH0", "url": "https://www.uniprot.org/uniprotkb/F1SEH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SEH0-1", "url": "https://www.uniprot.org/uniprotkb/F1SEH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEREKGSSSEKEGSEDERSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGRARGSDNDSDSGSDGGGQRSRSHSRSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD", "length": 532, "header": "tr|A0A5G2R5V9-1|A0A5G2R5V9_PIG Isoform 1 of RNA polymerase II-associated factor 1 homolog OS=Sus scrofa OX=9823 GN=PAF1 PE=1 SV=1 CANONICAL=A0A5G2R5V9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9/entry#A0A5G2QQP9-1", "sequence": { "sequence": "MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKVRSRAGGREGSPVISGCPILIPVPSIPQMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEREKGSSSEKEGSEDERSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGRARGSDNDSDSGSDGGGQRSRSHSRSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD", "length": 560, "header": "tr|A0A5G2QQP9-1|A0A5G2R5V9_PIG Computationally mapped isoform of RNA polymerase II-associated factor 1 homolog OS=Sus scrofa OX=9823 GN=PAF1 PE=1 SV=1 CANONICAL=A0A5G2R5V9-1" }, "locus": { "chromosome": "6", "start_pos": 48051596, "end_pos": 48046848, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073448.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073448.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064390.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064390.1" } ] } }, { "isoform_ac": "A0A5G2R544-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9/entry#A0A5G2R544-1", "sequence": { "sequence": "MAPTIQTQAQREDGHRSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSVMLIQRMTLTLTMRTEDGPEAVTMIRTVAVMGVASGAGATAGAGVPVPSPVAASILLRRMAVKLQLRIPVKLTVTVTESQGLQGWSRYNYYAQEGTFQVVYLQAFCFVSLSSSKPLLFNKATFLYFPSQALQSPSAPSSHPHPHRCLRHRSKGHRGRATRFSMKCSITKVRILFVCLFFLFFQNKPRPLNK", "length": 575, "header": "tr|A0A5G2R544-1|A0A5G2R5V9_PIG Computationally mapped isoform of RNA polymerase II-associated factor 1 homolog OS=Sus scrofa OX=9823 GN=PAF1 PE=1 SV=2 CANONICAL=A0A5G2R5V9-1" }, "locus": { "chromosome": "6", "start_pos": 48051596, "end_pos": 48046505, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085478.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085478.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069295.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069295.2" } ] } }, { "isoform_ac": "A0A5G2R5V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9/entry#A0A5G2R5V9-1", "sequence": { "sequence": "MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEREKGSSSEKEGSEDERSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGRARGSDNDSDSGSDGGGQRSRSHSRSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD", "length": 532, "header": "tr|A0A5G2R5V9-1|A0A5G2R5V9_PIG Isoform 1 of RNA polymerase II-associated factor 1 homolog OS=Sus scrofa OX=9823 GN=PAF1 PE=1 SV=1 CANONICAL=A0A5G2R5V9-1" }, "locus": { "chromosome": "6", "start_pos": 48051596, "end_pos": 48046848, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090424.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090424.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065975.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065975.1" } ] } }, { "isoform_ac": "F1SEH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9/entry#F1SEH0-1", "sequence": { "sequence": "MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEREKGSSSEKEGSEDERSGSESEREEGDRDEAIPSPVAASILLRRMAVKLQLRIPVKLTVTVTESQGLQGWSRYNYYAQEGTFQVVYLQAFCFVSLSSSKPLLFNKATFLYFPSQ", "length": 511, "header": "tr|F1SEH0-1|F1SEH0_PIG Computationally mapped isoform of RNA polymerase II-associated factor 1 homolog OS=Sus scrofa OX=9823 GN=PAF1 PE=1 SV=2 CANONICAL=A0A5G2R5V9-1" }, "locus": { "chromosome": "6", "start_pos": 48051596, "end_pos": 48046691, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036353.4", "url": "https://www.ensembl.org/id/ENSSSCT00000036353.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030019.2", "url": "https://www.ensembl.org/id/ENSSSCP00000030019.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R544", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R544" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514194", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514194", "resource": "KEGG Pathway" }, { "id": "R-SSC-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-SSC-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-SSC-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" }, { "id": "R-SSC-8866654", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8866654", "resource": "Reactome", "description": "E3 ubiquitin ligases ubiquitinate target proteins" }, { "id": "R-SSC-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XVQ2-1", "protein_name": "RNA polymerase II-associated factor 1 homolog", "gene_name": "PAF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPTIQTQAQREEPGHRPGSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPSGELGPEGPLGGDKGGREGNRRWGDAGGFLWQCSWTRRMRSCWRRRSRHPPAPRGNGAPGPTLEPAGAQLSPESLEEPPIQPRVTHPTLRPRSQQHAKVVPWMRKTEYISTEFNRYGVSNEKPEVKIGVSVKQQFTEEEIYKDRDSQIAAIEKTFEDAQKAITQHYSKPRVTPLEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLRKRKRDQEEEMDYAPEDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRARAGVQSGTNAVLVVKHRDMNEKELEAQEARRAQLENHEPEEEEEEEMEAEKEAPGSDEEREKGSESEGAASGEEEEEAEGSGASSSEQGGSAHSEDDAEDEEEEAARGARRGGSDAARAARDQEEIFGSDDDEDEEDDDDEEESEGGGSEGGPPRSPRLSPSEASEDEESASEASDSSSD", "length": 586 }, "evidence": [ { "id": "A0A5G2R5V9", "url": "https://omabrowser.org/oma/group/A0A5G2R5V9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q2KJ14-1", "protein_name": "RNA polymerase II-associated factor 1 homolog", "gene_name": "PAF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGASDEEREKGSSSEKEGSEDERSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGRARGSDNDSDSGSDGGGQRSRSHSRSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD", "length": 532 }, "evidence": [ { "id": "A0A5G2R5V9", "url": "https://omabrowser.org/oma/group/A0A5G2R5V9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4V886-1", "protein_name": "RNA polymerase II-associated factor 1 homolog", "gene_name": "Paf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMEAEEKEAGGSDEEHEKGSSSEKEGSEDERSGSESDREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAHRGSDNDSDSGSDGGGQRSRSQSRSRSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD", "length": 535 }, "evidence": [ { "id": "A0A5G2R5V9", "url": "https://omabrowser.org/oma/group/A0A5G2R5V9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K2T8-1", "protein_name": "RNA polymerase II-associated factor 1 homolog", "gene_name": "Paf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMEAEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESDREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAHRGSDNDSDSGSDGGGQRSRSQSRSRSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD", "length": 535 }, "evidence": [ { "id": "A0A5G2R5V9", "url": "https://omabrowser.org/oma/group/A0A5G2R5V9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N7H5-1", "protein_name": "RNA polymerase II-associated factor 1 homolog", "gene_name": "PAF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD", "length": 531 }, "evidence": [ { "id": "A0A5G2R5V9", "url": "https://omabrowser.org/oma/group/A0A5G2R5V9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "protein localization to nucleus", "id": "GO:0034504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034504", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "endodermal cell fate commitment", "id": "GO:0001711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001711", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "negative regulation of myeloid cell differentiation", "id": "GO:0045638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045638", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "positive regulation of cell cycle G1/S phase transition", "id": "GO:1902808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902808", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" }, { "name": "Cdc73/Paf1 complex", "id": "GO:0016593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016593", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 479, "end_pos": 481 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZN6-1", "uniprot_ac": "A0A5G2QZN6", "uniprot_id": "A0A5G2QZN6_PIG", "mass": { "chemical_mass": 42945.0, "monoisotopic_mass": 42945.0 }, "refseq": {}, "gene_names": [ { "name": "CKM", "type": "recommended", "evidence": [ { "id": "A0A5G2QZN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6" } ] } ], "protein_names": [ { "name": "Creatine kinase M-type", "type": "recommended", "evidence": [ { "id": "A0A5G2QZN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6/entry#names_and_taxonomy" } ] }, { "name": "2.7.3.2", "type": "synonym", "evidence": [ { "id": "A0A5G2QZN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6/entry#names_and_taxonomy" } ] }, { "name": "Creatine kinase M chain", "type": "synonym", "evidence": [ { "id": "A0A5G2QZN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6/entry#names_and_taxonomy" } ] }, { "name": "Creatine phosphokinase M-type", "type": "synonym", "evidence": [ { "id": "A0A5G2QZN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6/entry#names_and_taxonomy" } ] }, { "name": "M-CK", "type": "synonym", "evidence": [ { "id": "A0A5G2QZN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FIY7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIY7#function" }, { "database": "UniProtKB", "id": "ARBA00037274", "url": "https://www.uniprot.org/uniprotkb/ARBA00037274#function" }, { "database": "UniProtKB", "id": "A0A5G2QZN6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6#function" }, { "database": "UniProtKB", "id": "A0A287AMP3", "url": "https://www.uniprot.org/uniprotkb/A0A287AMP3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CKM", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6", "locus": { "chromosome": "6", "start_pos": 51700507, "end_pos": 51714814, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036132", "url": "https://www.ensembl.org/id/ENSSSCG00000036132" } ] } } ], "crossref": [ { "id": "A0A5G2QZN6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZN6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000036132", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036132", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014746", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014746", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036802", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036802", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WGYLTSC", "url": "https://omabrowser.org/oma/group/WGYLTSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11547", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11547", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11547:SF63", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11547:SF63", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02807", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02807", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-71288", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17157", "url": "https://www.rhea-db.org/rhea/17157", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AMP3", "url": "https://www.uniprot.org/uniprotkb/A0A287AMP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AMP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZN6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIY7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIY7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFGNTHNKYKLNFKAEEEYPDLSKHNNHMAKALTLEIYKKLRDKETPSGFTLDDVIQTGVDPGHPFIMTVGCVAGDEESYVVFKDLFDPIIQDRHGGYKPTDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK", "length": 380, "header": "tr|A0A5G2QZN6-1|A0A5G2QZN6_PIG Isoform 1 of Creatine kinase M-type OS=Sus scrofa OX=9823 GN=CKM PE=1 SV=1 CANONICAL=A0A5G2QZN6-1" }, "isoforms": [ { "isoform_ac": "A0A287AMP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6/entry#A0A287AMP3-1", "sequence": { "sequence": "MPFGNTHNKYKLNFKAEEEYPDLSKHNNHMAKALTLEIYKKLRDKETPSGFTLDDVIQTGVDNQGHPFIMTVGCVAGDEESYVVFKDLFDPIIQDRHGGYKPTDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQELWLTEAP", "length": 357, "header": "tr|A0A287AMP3-1|A0A5G2QZN6_PIG Computationally mapped isoform of Creatine kinase M-type OS=Sus scrofa OX=9823 GN=CKM PE=1 SV=1 CANONICAL=A0A5G2QZN6-1" }, "locus": { "chromosome": "6", "start_pos": 51712422, "end_pos": 51704086, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075869.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075869.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061534.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061534.2" } ] } }, { "isoform_ac": "A0A5G2QZN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6/entry#A0A5G2QZN6-1", "sequence": { "sequence": "MPFGNTHNKYKLNFKAEEEYPDLSKHNNHMAKALTLEIYKKLRDKETPSGFTLDDVIQTGVDPGHPFIMTVGCVAGDEESYVVFKDLFDPIIQDRHGGYKPTDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK", "length": 380, "header": "tr|A0A5G2QZN6-1|A0A5G2QZN6_PIG Isoform 1 of Creatine kinase M-type OS=Sus scrofa OX=9823 GN=CKM PE=1 SV=1 CANONICAL=A0A5G2QZN6-1" }, "locus": { "chromosome": "6", "start_pos": 51712422, "end_pos": 51704354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087584.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087584.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070358.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070358.1" } ] } }, { "isoform_ac": "A0A8W4FIY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6/entry#A0A8W4FIY7-1", "sequence": { "sequence": "MTVGCVAGDEESYVVFKDLFDPIIQDRHGGYKPTDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYAAWRRACEAGTPEQASQVRGDSHSSAPAEAGHRWRGHSRCGLSVRCIQRRSAGLVGGRTGAAGGGWCEAHGGDGEEAGKRPVHRRHDPRPEVGSQPTAGAQGKGRTKPIEGPPLPSRIWLTRVSQPGALSPLFIEFQFQPEFQPMGSILWVLANENPPFTFTFHYP", "length": 376, "header": "tr|A0A8W4FIY7-1|A0A5G2QZN6_PIG Computationally mapped isoform of Creatine kinase M-type OS=Sus scrofa OX=9823 GN=CKM PE=1 SV=1 CANONICAL=A0A5G2QZN6-1" }, "locus": { "chromosome": "6", "start_pos": 51711171, "end_pos": 51704130, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093010.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093010.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078844.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078844.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FIY7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIY7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-71288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71288", "resource": "Reactome", "description": "Creatine metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A2BHA3-1", "protein_name": "creatine kinase", "gene_name": "ckma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPFGNTHNNFKLNYSVDEEYPDLSKHNNHMAKVLTKEMYGKLRDKQTSTGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKDLFDPVISDRHGGYKATDKHKTDLNFENLKGGDDLDPNYVLSSRVRTGRSIKGYALPPHNSRGERRAVEKLSVEALSSLDGEFKGKYYPLKSMTDAEQEQLIADHFLFDKPVSPLLLAAGMARDWPDARGIWHNENKTFLVWVNEEDHLRVISMQKGGNMKEVFKRFCVGLQRIEEIFKKHNHGFMWNEHLGFVLTCPSNLGTGLRGGVHVKLPKLSTHAKFEEILTRLRLQKRGTGGVDTASVGGVFDISNADRIGSSEVEQVQCVVDGVKLMVEMEKKLEKGESIDSMIPAQK", "length": 381 }, "evidence": [ { "id": "A0A5G2QZN6", "url": "https://omabrowser.org/oma/group/A0A5G2QZN6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P06732-1", "protein_name": "Creatine kinase M-type", "gene_name": "CKM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDKETPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKPTDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK", "length": 381 }, "evidence": [ { "id": "A0A5G2QZN6", "url": "https://omabrowser.org/oma/group/A0A5G2QZN6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9XSC6-1", "protein_name": "Creatine kinase M-type", "gene_name": "CKM", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFGNTHNKHKLNFKAEEEYPDLSKHNNHMAKALTLEIYKKLRDKETPSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYTVFKDLFDPIIQDRHGGFKPTDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYALPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK", "length": 381 }, "evidence": [ { "id": "A0A5G2QZN6", "url": "https://omabrowser.org/oma/group/A0A5G2QZN6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phosphocreatine biosynthetic process", "id": "GO:0046314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046314", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "creatine kinase activity", "id": "GO:0004111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004111", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17157", "name": "", "equation": "creatine + ATP = N-phosphocreatine + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17157", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17157" } ] }, { "id": "R-SSC-200318", "name": "creatine + ATP => phosphocreatine + ADP [CKB,CKM]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29916" ], "output_participant_list": [ "R-ALL-200351" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-200318", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-200318" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-200351", "participant_name": "Pcr [cytosol]", "crossref": [ { "id": "ZINC000003869774", "database": "ZINC", "url": "" }, { "id": "58092", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-29916", "participant_name": "CRET [cytosol]", "crossref": [ { "id": "57947", "database": "ChEBI", "url": "" }, { "id": "ZINC000003861770", "database": "ZINC", "url": "" }, { "id": "C00300", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZN6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 380, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZN6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZN6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6" }, { "id": "PS51510", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51510" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphagen kinase C-terminal", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 366, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QZN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN6" }, { "id": "PS51509", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51509" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphagen kinase N-terminal", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 97, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 221, "end_pos": 223 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZC7-1", "uniprot_ac": "A0A5G2QZC7", "uniprot_id": "A0A5G2QZC7_PIG", "mass": { "chemical_mass": 77908.0, "monoisotopic_mass": 77908.0 }, "refseq": {}, "gene_names": [ { "name": "MED25", "type": "recommended", "evidence": [ { "id": "A0A5G2QZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ] } ], "protein_names": [ { "name": "Mediator of RNA polymerase II transcription subunit 25", "type": "recommended", "evidence": [ { "id": "A0A5G2QZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Activates transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS42", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS42#function" }, { "database": "UniProtKB", "id": "RU369088", "url": "https://www.uniprot.org/uniprotkb/RU369088#function" } ] }, { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.", "evidence": [ { "database": "UniProtKB", "id": "F1RHT9", "url": "https://www.uniprot.org/uniprotkb/F1RHT9#function" }, { "database": "UniProtKB", "id": "RU369088", "url": "https://www.uniprot.org/uniprotkb/RU369088#function" }, { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MED25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7", "locus": { "chromosome": "6", "start_pos": 54852821, "end_pos": 54834316, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003197", "url": "https://www.ensembl.org/id/ENSSSCG00000003197" } ] } } ], "crossref": [ { "id": "A0A5G2QZC7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZC7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003197", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003197", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR021394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021419", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021419", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038196", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038196", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12433", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12433", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12433:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12433:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11232", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11232", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11235", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11235", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11265", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11265", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18658", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18658", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QS42", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS42-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RHT9", "url": "https://www.uniprot.org/uniprotkb/F1RHT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RHT9-1", "url": "https://www.uniprot.org/uniprotkb/F1RHT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIYFSIVSPRKLPALRLLFEKAAPPAMLEPLQPPADVSQDPRHMVLVRGLVLPVGGGSAPGPLQPKQPVPLPPAPPSGATLSAAPQQPLPPVPQQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAAPGVGPPYSQAAPPMPSGAPGASKPPPASQPSLVSTVAPGPGLAPSAQPGAPSMAGTVAPGGVSGPSAAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLDSLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQAPPGLGPILEDQARPSQNLLQLRPPQPQPQGAVGASAATGQPQPQGTAQAPPGAPQGPPGAAPGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI", "length": 745, "header": "tr|A0A5G2QZC7-1|A0A5G2QZC7_PIG Isoform 1 of Mediator of RNA polymerase II transcription subunit 25 OS=Sus scrofa OX=9823 GN=MED25 PE=3 SV=1 CANONICAL=A0A5G2QZC7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QS42-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7/entry#A0A5G2QS42-1", "sequence": { "sequence": "MVLGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAAPGVGPPYSQAAPPMPSGAPGASKPPPASQPSLVSTVAPGPGLAPSAQPGAPSMAGTVAPGGVSGPSAAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLDSLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQAPPGLGPILEDQARPSQNLLQLRPPQPQPQGAVGASAATGQPQPQGTAQAPPGAPQGPPGAAPGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI", "length": 532, "header": "tr|A0A5G2QS42-1|A0A5G2QZC7_PIG Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 25 OS=Sus scrofa OX=9823 GN=MED25 PE=3 SV=1 CANONICAL=A0A5G2QZC7-1" }, "locus": { "chromosome": "6", "start_pos": 54849501, "end_pos": 54834381, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074134.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074134.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067750.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067750.1" } ] } }, { "isoform_ac": "A0A5G2QZC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7/entry#A0A5G2QZC7-1", "sequence": { "sequence": "MVLGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIYFSIVSPRKLPALRLLFEKAAPPAMLEPLQPPADVSQDPRHMVLVRGLVLPVGGGSAPGPLQPKQPVPLPPAPPSGATLSAAPQQPLPPVPQQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAAPGVGPPYSQAAPPMPSGAPGASKPPPASQPSLVSTVAPGPGLAPSAQPGAPSMAGTVAPGGVSGPSAAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLDSLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQAPPGLGPILEDQARPSQNLLQLRPPQPQPQGAVGASAATGQPQPQGTAQAPPGAPQGPPGAAPGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI", "length": 745, "header": "tr|A0A5G2QZC7-1|A0A5G2QZC7_PIG Isoform 1 of Mediator of RNA polymerase II transcription subunit 25 OS=Sus scrofa OX=9823 GN=MED25 PE=3 SV=1 CANONICAL=A0A5G2QZC7-1" }, "locus": { "chromosome": "6", "start_pos": 54849501, "end_pos": 54834381, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088354.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088354.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067303.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067303.1" } ] } }, { "isoform_ac": "F1RHT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7/entry#F1RHT9-1", "sequence": { "sequence": "MVLGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIYFSIVSPRKLPALRLLFEKAAPPAMLEPLQPPADVSQDPRHMVLVRGLVLPVGGGSAPGPLQPKQPVPLPPAPPSGATLSAAPQQPLPPVPQQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAAPGVGPPYSQAAPPMPSGAPGASKPPPASQPSLVSTVAPGPGLAPSAQPGAPSMAGTVAPGGVSGPSAAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLDSLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQAPPGLGPILEDQARPSQNLLQLRPPQPQPQGAVGASAATGQPQPQGTAQAPPGAPQGPPGAAPGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPVAKRKREREGHVFREKWERAYFFVEVKSLPTCLICKKIVSVLKEYNLRRHYESKHSKSFDQYTEQTRDAILSELKKGLKCQ", "length": 794, "header": "tr|F1RHT9-1|A0A5G2QZC7_PIG Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 25 OS=Sus scrofa OX=9823 GN=MED25 PE=3 SV=4 CANONICAL=A0A5G2QZC7-1" }, "locus": { "chromosome": "6", "start_pos": 54851353, "end_pos": 54834381, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003552.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003552.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003469.4", "url": "https://www.ensembl.org/id/ENSSSCP00000003469.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RHT9", "url": "https://www.uniprot.org/uniprotkb/F1RHT9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of mediator complex assembly", "id": "GO:2001178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001178", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" }, { "name": "negative regulation of fibroblast proliferation", "id": "GO:0048147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048147", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator binding", "id": "GO:0001223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001223", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" }, { "name": "nuclear retinoid X receptor binding", "id": "GO:0046965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046965", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZC7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 745, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZC7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZC7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" }, { "id": "PF11232", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11232" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator complex subunit Med25 PTOV", "eco_id": "ECO_0000259", "start_pos": 396, "end_pos": 545, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" }, { "id": "PF11235", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator complex subunit Med25 synapsin 1", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 382, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZC7" }, { "id": "PF11265", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11265" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator of RNA polymerase II transcription subunit 25 von Willebrand factor type A", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 226, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 277, "end_pos": 279 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R4A1-1", "uniprot_ac": "A0A5G2R4A1", "uniprot_id": "A0A5G2R4A1_PIG", "mass": { "chemical_mass": 41606.0, "monoisotopic_mass": 41606.0 }, "refseq": {}, "gene_names": [ { "name": "PGAP3", "type": "recommended", "evidence": [ { "id": "A0A5G2R4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1" } ] } ], "protein_names": [ { "name": "Post-GPI attachment to proteins factor 3", "type": "recommended", "evidence": [ { "id": "A0A5G2R4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in the fatty acid remodeling steps of GPI-anchor maturation where the unsaturated acyl chain at sn-2 of inositol phosphate is replaced by a saturated stearoyl chain. May catalyze the first step of the fatty acid remodeling, by removing the unsaturated acyl chain at sn-2 of inositol phosphate, generating a lyso-GPI intermediate. The fatty acid remodeling steps is critical for the integration of GPI-APs into lipid rafts.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ADB1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADB1#function" }, { "database": "UniProtKB", "id": "ARBA00093305", "url": "https://www.uniprot.org/uniprotkb/ARBA00093305#function" }, { "database": "UniProtKB", "id": "F1RWL4", "url": "https://www.uniprot.org/uniprotkb/F1RWL4#function" }, { "database": "UniProtKB", "id": "A0A5G2R4A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1#function" }, { "database": "UniProtKB", "id": "A0A5G2Q9U9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9U9#function" } ] }, { "annotation": "Involved in the lipid remodeling steps of GPI-anchor maturation.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ADB1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADB1#function" }, { "database": "UniProtKB", "id": "RU365066", "url": "https://www.uniprot.org/uniprotkb/RU365066#function" }, { "database": "UniProtKB", "id": "F1RWL4", "url": "https://www.uniprot.org/uniprotkb/F1RWL4#function" }, { "database": "UniProtKB", "id": "A0A5G2R4A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1#function" }, { "database": "UniProtKB", "id": "A0A5G2Q9U9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9U9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PGAP3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1", "locus": { "chromosome": "12", "start_pos": 22647813, "end_pos": 22630435, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017502", "url": "https://www.ensembl.org/id/ENSSSCG00000017502" } ] } } ], "crossref": [ { "id": "A0A5G2R4A1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4A1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017502", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017502", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100516999", "url": "https://www.ncbi.nlm.nih.gov/gene/100516999", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1RWL4", "url": "https://www.orthodb.org/?gene=F1RWL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13148", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13148", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13148:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13148:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04080", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04080", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "83847", "url": "https://www.rhea-db.org/rhea/83847", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287ADB1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ADB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q9U9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q9U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWL4", "url": "https://www.uniprot.org/uniprotkb/F1RWL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWL4-1", "url": "https://www.uniprot.org/uniprotkb/F1RWL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWRTARLLLLAGAAALASGSQGDREPVYRDCLLQCEERNCSGGALKHFRSHQPIYMSLAGWTCRDDCKYECMWVTVGLYLQEGHKVPQFHGKWPFSRFLCFQEPASAVASFLNGLASLVMLCRYRASVPASSPMYPTCVAFAWVSLNAWFWSTVFHTRDTDLTEVSASHSLLCLGQPRRSPGEVGQRRLFLLRTHSVSGSPEHLPYAGHFRSKLDYFCASTVILHSVYLCCVRTVGLQRPAVASAFRALLLLMLTAHVSYLSLVHFDYGYNLAANVAMGLVNAAWWLAWCLRNRRRLPHVRKCMVVVLLLQALSLLELLDFPPLFWVLDAHAIWHISTIPVHVLFFSFLEDDSLYLLKESEAKFKLA", "length": 368, "header": "tr|A0A5G2R4A1-1|A0A5G2R4A1_PIG Isoform 1 of Post-GPI attachment to proteins factor 3 OS=Sus scrofa OX=9823 GN=PGAP3 PE=3 SV=1 CANONICAL=A0A5G2R4A1-1" }, "isoforms": [ { "isoform_ac": "A0A287ADB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1/entry#A0A287ADB1-1", "sequence": { "sequence": "MAWRTARLLLLAGAAALASGSQGDREPVYRDCLLQCEERNCSGGALKHFRSHQPIYMSLAGWTCRDDCKYECMWVTVGLYLQEGHKVPQFHGKWPFSRFLCFQEPASAVASFLNGLASLVMLCRYRASVPASSPMYPTCVAFAWKLDYFCASTVILHSVYLCCVRTVGLQRPAVASAFRALLLLMLTAHVSYLSLVHFDYGYNLAANVAMGLVNAAWWLAWCLRNRRRLPHVRKCMVVVLLLQALSLLELLDFPPLFWVLDAHAIWHISTIPVHVLFFSFLEDDSLYLLKESEAKFKLA", "length": 299, "header": "tr|A0A287ADB1-1|A0A5G2R4A1_PIG Computationally mapped isoform of Post-GPI attachment to proteins factor 3 OS=Sus scrofa OX=9823 GN=PGAP3 PE=3 SV=2 CANONICAL=A0A5G2R4A1-1" }, "locus": { "chromosome": "12", "start_pos": 22645921, "end_pos": 22630571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040318.2", "url": "https://www.ensembl.org/id/ENSSSCT00000040318.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041999.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041999.2" } ] } }, { "isoform_ac": "A0A5G2Q9U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1/entry#A0A5G2Q9U9-1", "sequence": { "sequence": "MAWRTARLLLLAGAAALASGSQGDREPVYRDCLLQCEERNCSGGALKHFRSHQPIYMSLAGWTCRDDCKYECMWVTVGLYLQEGHKVPQFHGKWPFSRFLCFQEPASAVASFLNGLASLVMLCRYRASVPASSPMYPTCVAFAWLSGR", "length": 148, "header": "tr|A0A5G2Q9U9-1|A0A5G2Q9U9_PIG Computationally mapped isoform of Post-GPI attachment to proteins factor 3 OS=Sus scrofa OX=9823 GN=PGAP3 PE=3 SV=1 CANONICAL=A0A5G2R4A1-1" }, "locus": { "chromosome": "12", "start_pos": 22645872, "end_pos": 22630571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078772.1", "url": "https://www.ensembl.org/id/ENSSSCT00000078772.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060108.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060108.1" } ] } }, { "isoform_ac": "A0A5G2R4A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1/entry#A0A5G2R4A1-1", "sequence": { "sequence": "MAWRTARLLLLAGAAALASGSQGDREPVYRDCLLQCEERNCSGGALKHFRSHQPIYMSLAGWTCRDDCKYECMWVTVGLYLQEGHKVPQFHGKWPFSRFLCFQEPASAVASFLNGLASLVMLCRYRASVPASSPMYPTCVAFAWVSLNAWFWSTVFHTRDTDLTEVSASHSLLCLGQPRRSPGEVGQRRLFLLRTHSVSGSPEHLPYAGHFRSKLDYFCASTVILHSVYLCCVRTVGLQRPAVASAFRALLLLMLTAHVSYLSLVHFDYGYNLAANVAMGLVNAAWWLAWCLRNRRRLPHVRKCMVVVLLLQALSLLELLDFPPLFWVLDAHAIWHISTIPVHVLFFSFLEDDSLYLLKESEAKFKLA", "length": 368, "header": "tr|A0A5G2R4A1-1|A0A5G2R4A1_PIG Isoform 1 of Post-GPI attachment to proteins factor 3 OS=Sus scrofa OX=9823 GN=PGAP3 PE=3 SV=1 CANONICAL=A0A5G2R4A1-1" }, "locus": { "chromosome": "12", "start_pos": 22645921, "end_pos": 22630571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077502.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077502.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071163.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071163.1" } ] } }, { "isoform_ac": "F1RWL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1/entry#F1RWL4-1", "sequence": { "sequence": "MAWRTARLLLLAGAAALASGSQGDREPVYRDCLLQCEERNCSGGALKHFRSHQPIYMSLAGWTCRDDCKYECMWVTVGLYLQEGHKVPQFHGKVSLNAWFWSTVFHTRDTDLTEKLDYFCASTVILHSVYLCCVRTVGLQRPAVASAFRALLLLMLTAHVSYLSLVHFDYGYNLAANVAMGLVNAAWWLAWCLRNRRRLPHVRKCMVVVLLLQALSLLELLDFPPLFWVLDAHAIWHISTIPVHVLFFSFLEDDSLYLLKESEAKFKLA", "length": 269, "header": "tr|F1RWL4-1|A0A5G2R4A1_PIG Computationally mapped isoform of Post-GPI attachment to proteins factor 3 OS=Sus scrofa OX=9823 GN=PGAP3 PE=3 SV=2 CANONICAL=A0A5G2R4A1-1" }, "locus": { "chromosome": "12", "start_pos": 22645921, "end_pos": 22630571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019055.3", "url": "https://www.ensembl.org/id/ENSSSCT00000019055.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018550.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018550.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ADB1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADB1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity, acting on ester bonds", "id": "GO:0016788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016788", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4A1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "83847", "name": "", "equation": "[protein]-C-terminal carboxyl phosphoethanolamide-GPI(deacylinositol-H7) + H2O = [protein]-C-terminal carboxyl phosphoethanolamide-lysoGPI(deacylinositol-H7) + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83847", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83847" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R4A1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 368, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R4A1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4A1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0L8-1", "uniprot_ac": "A0A5G2R0L8", "uniprot_id": "A0A5G2R0L8_PIG", "mass": { "chemical_mass": 120835.0, "monoisotopic_mass": 120835.0 }, "refseq": {}, "gene_names": [ { "name": "ESYT1", "type": "recommended", "evidence": [ { "id": "A0A5G2R0L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ] } ], "protein_names": [ { "name": "Extended synaptotagmin-1", "type": "recommended", "evidence": [ { "id": "A0A5G2R0L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Acts as an inhibitor of ADGRD1 G-protein-coupled receptor activity in absence of cytosolic calcium. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport.", "evidence": [ { "database": "UniProtKB", "id": "F1SPG9", "url": "https://www.uniprot.org/uniprotkb/F1SPG9#function" }, { "database": "UniProtKB", "id": "ARBA00093357", "url": "https://www.uniprot.org/uniprotkb/ARBA00093357#function" }, { "database": "UniProtKB", "id": "A0A287ASV9", "url": "https://www.uniprot.org/uniprotkb/A0A287ASV9#function" }, { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ESYT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8", "locus": { "chromosome": "5", "start_pos": 21535929, "end_pos": 21514510, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000379", "url": "https://www.ensembl.org/id/ENSSSCG00000000379" } ] } } ], "crossref": [ { "id": "A0A5G2R0L8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0L8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000379", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000379", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04050", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04050", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08391", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08391", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21679", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21679", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45761", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45761", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45761:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45761:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9845576", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9845576", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AH93", "url": "https://www.uniprot.org/uniprotkb/A0A287AH93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AH93-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AH93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASV9", "url": "https://www.uniprot.org/uniprotkb/A0A287ASV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ASV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SPG9", "url": "https://www.uniprot.org/uniprotkb/F1SPG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SPG9-1", "url": "https://www.uniprot.org/uniprotkb/F1SPG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERSPGDRSSPVDQPYAPSDPPDQPPVAPTKPDQSSGNQPAGPGAAGEALAVLTSFGRRLLVLVPVYLAGAMGLSVGFVLFGLALYLGWRRVREEKERSLRVAQQLLEDEERLTAKTLYMSQRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGSNPHLQTFTFTRVELGEKPLRILGVKVHPGQRKEQILLDLNISYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLPIVGAVSMFFIRRPTLDINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRVHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQAFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAAVMDEWFPLQGGQGQVHLRLEWLSLLPDAEKLEQILQWNRGVSSRPEPPSAAILVVYLDRAQDLPVVTSEFYSLQLKKGNKEPNPMVQLSVQDVTQESKAVYSTNSPVWEEAFRFFLQDPRSQELDVQVKDDSRALTLGALTLPLARLLTAPELTLDQWFQVWSWRKCEVRFPAGPGTPEAWDLDNESPQTGSSVDTPPRPSHTTPDSNFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSRVIREDLNPHWNEVFEVIVTSIPGQELEAEVFDKDLDKDDFLGRCKVSLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALLSVYLERAEDLPLRKGTKPPSPYATLAVGETSHKTKTVPQTSAPIWDESASFLIRKPNIESLELQVRGEGTGVLGSLSLPLSELLVADRLCLDRWFTLSSGQGQVLLRAQLGILVSQHSGVEAHSHSHSSSSLSEEPELWGGLPHVTSSAPELRQRLTHGDSPQEAPAGPLGQVKLTVWYYSEERKLVSMVHSCRALRQNGRDPPDPYVSLLLLPDKNRGTKRKTSQKKRTLNPEFNERFEWELPLDEALRRKLDVSVKSSSSFMSRERELLGKVRGQGGQGQGRVRSCQWQGL", "length": 1084, "header": "tr|A0A5G2R0L8-1|A0A5G2R0L8_PIG Isoform 1 of Extended synaptotagmin-1 OS=Sus scrofa OX=9823 GN=ESYT1 PE=1 SV=2 CANONICAL=A0A5G2R0L8-1" }, "isoforms": [ { "isoform_ac": "A0A287AH93-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8/entry#A0A287AH93-1", "sequence": { "sequence": "MERSPGDRSSPPPVAPTKPDQSSGNQPAGPGAAGEALAVLTSFGRRLLVLVPVYLAGAMGLSVGFVLFGLALYLGWRRVREEKERSLRVAQQLLEDEERLTAKTLYMSQRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGSNPHLQTFTFTRVELGEKPLRILGVKVHPGQRKEQILLDLNISYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLPIVGAVSMFFIRRPTLDINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRVHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQAFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAAVMDEWFPLQGGQGQVHLRLEWLSLLPDAEKLEQILQWNRGVSSRPEPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQLSVQDVTQESKAVYSTNSPVWEEAFRFFLQDPRSQELDVQVKDDSRALTLGALTLPLARLLTAPELTLDQWFQLSMRFPAGPGTPEAWDLDNESPQTGSSVDTPPRPSHTTPDSNFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSRVIREDLNPHWNEVFETLILIFYRCKVSLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALLSVYLERAEDLPLRKGTKPPSPYATLAVGETSHKTKTVPQTSAPIWDESASFLIRKPNIESLELQVRGEGTGVLGSLSLPLSELLVADRLCLDRWFTLSSGQGQVLLRAQLGILVSQHSGVEAHSHSHSSSSLSEEPELWGGLPHVTSSAPELRQRLTHGDSPQEAPAGPLGQVKLTVWYYSEERKLVSMVHSCRALRQNGRDPPDPYVSLLLLPDKNRGTKRKTSQKKRTLNPEFNERFEWELPLDEALRRKLDVSVKSSSSFMSRERELLGKVRGQGGQGQGRVRSCQWQGL", "length": 1035, "header": "tr|A0A287AH93-1|A0A5G2R0L8_PIG Computationally mapped isoform of Extended synaptotagmin-1 OS=Sus scrofa OX=9823 GN=ESYT1 PE=1 SV=2 CANONICAL=A0A5G2R0L8-1" }, "locus": { "chromosome": "5", "start_pos": 21533066, "end_pos": 21518070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055523.2", "url": "https://www.ensembl.org/id/ENSSSCT00000055523.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043227.2", "url": "https://www.ensembl.org/id/ENSSSCP00000043227.2" } ] } }, { "isoform_ac": "A0A287ASV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8/entry#A0A287ASV9-1", "sequence": { "sequence": "MERSPGDRSSPVDQPYAPSDPPDQPPVAPTKPDQSSGNQPAGPGAAGEALAVLTSFGRRLLVLVPVYLAGAMGLSVGFVLFGLALYLGWRRVREEKERSLRVAQQLLEDEERLTAKTLYMSQRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGSNPHLQTFTFTRVELGEKPLRILGVKVHPGQRKEQILLDLNISYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLPIVGAVSMFFIRRPTLDINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRVHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQAFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAAVMDEWFPLQGGQGQVHLRLEWLSLLPDAEKLEQILQWNRGVSSRPEPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQLSVQDVTQESKAVYSTNSPVWEEAFRFFLQDPRSQELDVQVKDDSRALTLGALTLPLARLLTAPELTLDQWFQLSKVRFPAGPGTPEAWDLDNESPQTGSSVDTPPRPSHTTPDSNFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSRVIREDLNPHWNEVFEVIVTSIPGQELEAEVFDKDLDKDDFLGRCKVSLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALLSVYLERAEDLPLRKGTKPPSPYATLAVGETSHKTKTVPQTSAPIWDESASFLIRKPNIESLELQVRGEGTGVLGSLSLPLSELLVADRLCLDRWFTLSSGQGQVLLRAQLGILVSQHSGVEAHSHSHSSSSLSEEPELWGGLPHVTSSAPELRQRLTHGDSPQEAPAGPLGQVKLTVWYYSEERKLVSMVHSCRALRQNGRDPPDPYVSLLLLPDKNRGTKRKTSQKKRTLNPEFNERFEWELPLDEALRRKLDVSVKSSSSFMSRERELLGKVRGQGGQGQGRVRSCQWQGL", "length": 1069, "header": "tr|A0A287ASV9-1|A0A5G2R0L8_PIG Computationally mapped isoform of Extended synaptotagmin-1 OS=Sus scrofa OX=9823 GN=ESYT1 PE=1 SV=2 CANONICAL=A0A5G2R0L8-1" }, "locus": { "chromosome": "5", "start_pos": 21533066, "end_pos": 21518070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050279.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050279.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047170.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047170.2" } ] } }, { "isoform_ac": "A0A5G2R0L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8/entry#A0A5G2R0L8-1", "sequence": { "sequence": "MERSPGDRSSPVDQPYAPSDPPDQPPVAPTKPDQSSGNQPAGPGAAGEALAVLTSFGRRLLVLVPVYLAGAMGLSVGFVLFGLALYLGWRRVREEKERSLRVAQQLLEDEERLTAKTLYMSQRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGSNPHLQTFTFTRVELGEKPLRILGVKVHPGQRKEQILLDLNISYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLPIVGAVSMFFIRRPTLDINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRVHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQAFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAAVMDEWFPLQGGQGQVHLRLEWLSLLPDAEKLEQILQWNRGVSSRPEPPSAAILVVYLDRAQDLPVVTSEFYSLQLKKGNKEPNPMVQLSVQDVTQESKAVYSTNSPVWEEAFRFFLQDPRSQELDVQVKDDSRALTLGALTLPLARLLTAPELTLDQWFQVWSWRKCEVRFPAGPGTPEAWDLDNESPQTGSSVDTPPRPSHTTPDSNFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSRVIREDLNPHWNEVFEVIVTSIPGQELEAEVFDKDLDKDDFLGRCKVSLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALLSVYLERAEDLPLRKGTKPPSPYATLAVGETSHKTKTVPQTSAPIWDESASFLIRKPNIESLELQVRGEGTGVLGSLSLPLSELLVADRLCLDRWFTLSSGQGQVLLRAQLGILVSQHSGVEAHSHSHSSSSLSEEPELWGGLPHVTSSAPELRQRLTHGDSPQEAPAGPLGQVKLTVWYYSEERKLVSMVHSCRALRQNGRDPPDPYVSLLLLPDKNRGTKRKTSQKKRTLNPEFNERFEWELPLDEALRRKLDVSVKSSSSFMSRERELLGKVRGQGGQGQGRVRSCQWQGL", "length": 1084, "header": "tr|A0A5G2R0L8-1|A0A5G2R0L8_PIG Isoform 1 of Extended synaptotagmin-1 OS=Sus scrofa OX=9823 GN=ESYT1 PE=1 SV=2 CANONICAL=A0A5G2R0L8-1" }, "locus": { "chromosome": "5", "start_pos": 21533066, "end_pos": 21518070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090528.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090528.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070653.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070653.2" } ] } }, { "isoform_ac": "F1SPG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8/entry#F1SPG9-1", "sequence": { "sequence": "MERSPGDRSSPVDQPYPDQSSGNQPAGPGAAGEALAVLTSFGRRLLVLVPVYLAGAMGLSVGFVLFGLALYLGWRRVREEKERSLRVAQQLLEDEERLTAKTLYMSQRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGSNPHLQTFTFTRVELGEKPLRILGVKVHPGQRKEQILLDLNISYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLPIVGAVSMFFIRRPTLDINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRVHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQAFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAAVMDEWFPLQGGQGQVHLRLEWLSLLPDAEKLEQILQWNRGVSSRPEPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQLSVQDVTQESKAVYSTNSPVWEEAFRFFLQDPRSQELDVQVKDDSRALTLGALTLPLARLLTAPELTLDQWFQLSKVRFPAGPGTPEAWDLDNESPQTGSSVDTPPRPSHTTPDSNFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSRVIREDLNPHWNEVFEVIVTSIPGQELEAEVFDKDLDKDDFLGRCKVSLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALLSVYLERAEDLPLRKGTKPPSPYATLAVGETSHKTKTVPQTSAPIWDESASFLIRKPNIESLELQVRGEGTGVLGSLSLPLSELLVADRLCLDRWFTLSSGQGQVLLRAQLGILVSQHSGVEAHSHSHSSSSLSEEPELWGGLPHVTSSAPELRQRLTHGDSPQEAPAGPLGQVKLTVWYYSEERKLVSMVHSCRALRQNGRDPPDPYVSLLLLPDKNRGTKRKTSQKKRTLNPEFNERFEWELPLDEALRRKLDVSVKSSSSFMSRERELLGKVRGQGGQGQGRVRSCQWQGL", "length": 1054, "header": "tr|F1SPG9-1|F1SPG9_PIG Computationally mapped isoform of Extended synaptotagmin-1 OS=Sus scrofa OX=9823 GN=ESYT1 PE=1 SV=3 CANONICAL=A0A5G2R0L8-1" }, "locus": { "chromosome": "5", "start_pos": 21533066, "end_pos": 21518070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000405.4", "url": "https://www.ensembl.org/id/ENSSSCT00000000405.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000399.4", "url": "https://www.ensembl.org/id/ENSSSCP00000000399.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AH93", "url": "https://www.uniprot.org/uniprotkb/A0A287AH93" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-SSC-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-SSC-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-SSC-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-SSC-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" }, { "id": "R-SSC-9845576", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9845576", "resource": "Reactome", "description": "Glycosphingolipid transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane tethering", "id": "GO:0061817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061817", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" }, { "name": "phosphatidylethanolamine binding", "id": "GO:0008429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008429", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" }, { "name": "phosphatidylcholine binding", "id": "GO:0031210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031210", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" }, { "name": "phospholipid transfer activity", "id": "GO:0120014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120014", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0L8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1084, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0L8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0L8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 310, "end_pos": 431, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R0L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0L8" }, { "id": "PS51847", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51847" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SMP-LTD", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 311, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 271, "end_pos": 273 }, { "start_pos": 610, "end_pos": 612 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWE7-1", "uniprot_ac": "A0A5G2QWE7", "uniprot_id": "A0A5G2QWE7_PIG", "mass": { "chemical_mass": 258419.0, "monoisotopic_mass": 258419.0 }, "refseq": {}, "gene_names": [ { "name": "PTPRQ", "type": "recommended", "evidence": [ { "id": "A0A5G2QWE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ] } ], "protein_names": [ { "name": "Phosphatidylinositol phosphatase PTPRQ", "type": "recommended", "evidence": [ { "id": "A0A5G2QWE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.67", "type": "synonym", "evidence": [ { "id": "A0A5G2QWE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.86", "type": "synonym", "evidence": [ { "id": "A0A5G2QWE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.95", "type": "synonym", "evidence": [ { "id": "A0A5G2QWE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7/entry#names_and_taxonomy" } ] }, { "name": "Receptor-type tyrosine-protein phosphatase Q", "type": "synonym", "evidence": [ { "id": "A0A5G2QWE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PTPRQ", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7", "locus": { "chromosome": "5", "start_pos": 100787027, "end_pos": 101033334, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031716", "url": "https://www.ensembl.org/id/ENSSSCG00000031716" } ] } } ], "crossref": [ { "id": "ENSSSCG00000031716", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031716", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14616", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14616", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YYTVYIW", "url": "https://omabrowser.org/oma/group/YYTVYIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46957:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46957:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "25017", "url": "https://www.rhea-db.org/rhea/25017", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25528", "url": "https://www.rhea-db.org/rhea/25528", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "32955", "url": "https://www.rhea-db.org/rhea/32955", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "39019", "url": "https://www.rhea-db.org/rhea/39019", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287ASE8", "url": "https://www.uniprot.org/uniprotkb/A0A287ASE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ASE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VKKVATKPEKRKKRKALRISAPSFSLHWSLPSGHVDLVPDSGFVTITLLGGGEYQVDVSSAVPGTRYNVAISSISATTYSSPVSRTVTTNVTKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYIVKYKEVCPWMQAAYTQVRTKPDSLEVLLTNLNPGTTYEIKVAAENSAGLGVFSDPFLFQTAESAPGKVVNLTVEAFNDSAVNLIWYLPRQPNGKITSFKISVKHARSGIVVKDVSIRVEDLLTGKLPACNENNESFLWSTTSPAPMLDRVTPPPRTTHSSSVLARSKMSSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDSTIVRTPESVPEGPPQNCLTGNITGKSFSMSWDPPSTVTGKFSYRVELYGPSGRILDNSTKDLKFAFTNLTPFTMYDVYVAAETSAGIGPKSNISVFTPPDVPGAVFDLQVADVEATEVRITWKKPRQPNGIINRYRVKVLASETGVILENTLLTGRDEYINHPMAPETVNIVESMTGLFEGSAEMSSDLYSLASVIYNIHPHNFPARSGAEDQPSIVGTTRSQYIADIAAEQLSYVIRRLVPFTEHMISVSAFTIMGEGPPTALSVRTREQVPSSIQVINYKNISSSSILLFWDPPEYPNGKITHYTIYAMELDTNRAFQMTTVDNSFLITGLKKYTKYKMRVAASTNVGESSLSEANDIFVRTPEDEPESSPRDVEVIDVSAREISLKWSPPEKPNGIIVAYEVLCKNTDTLVTKNTSTTNITLGGLKPYTRYNISVRSYTRFGHGSQLSSLLSVSTSETAPDSAPENITYRNISSGEIELSFLPPNSPNGIIQKYTIYLKKSDGNEERTINTSSLTQSIKGLKKYTQYMIEVSASTLSGEGVRSLPISVLTEEDAPDSPPQDFSVKQLSGVMVKLSWQPPLEPNGIILYYTVYVWDVSSLKTVNVTETSLELSDLDYDSEYSAYVTASTRFGDGKRRSSIIHFRTPEGAPSDPPKDVHYANLSSSSIVLFWKPPSKPNGIIQYYSVHYRNTSGTFMQNFTLHEVTNDFDNMTVSAIIDKLAIFSYYTFWVTASTSVGNGNKSSDIVQVYTDQDTPEGLVGNLTYESMSSTAVNVSWGPPSQPNGLVFYYVSLSSEQTPRHVRPLLVTYERSVYFDNLEKYTDYILEITPSTEKGFSDTYTAQLHIKTEEDVPETSPIINTFKNLSSTSVLLSWDPPVKPNGAIISYDLTLQGPRENYSFVTSDNYLILEELSPFTLYSFFAAARTVKGLGPSSVLLFYTDESVPLAPPQNLTLINYTSDLVWLKWSPSPVPGGIVKLYSLKIHEHETDTIFYKNISGLQTEAQVVGLEPVSTYSVSISAFTKVGNGNQFSNVVKFTTQESVPDVVQNIQCVATSWQSALVKWDPPRKANGIITHYLITVEKNATKVFPQDHMHTFMKLFANTSYVFKIRASTSAGEGDERTCNVSTLPETVPSVPTNITFANIRSTSATLTWMRPDSIFGYFQNYKITTQLRAQTCREWESEGCVEHQKIQYLYEADLTEETIYGLKKFRWYRFQVAASTNAGYGNASDWISTQTLPGPPDGPPENVLVVATSPFSINISWSEPAVITGPTFYLIDVQSVDSDEFNISLIKSNEENKTIEIKDLKIFTRYSVVITAFTGNISAAYGEGKSSAKVIVTTLESVPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTDTSVVAVLEGLKGGYTYNISVYAINSAGAGPKVQMRITMDIKAPARPKTKPTPIYDATGKLLVTSTTITIRMPICYYSDDHGPIKNVQVLVAEAGAQHDGNVTKWYDAYFNKPRPYFTNEGFPNPPCTEGKTKFSGNEEIYIIGADNACMIPGNEDKICNGPLKPKKQYLFKFRATNIMGQFTDSDYSDPVKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPRDAEIIDTKFKLDQLITVADLELKDERLTRPISKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIADASIPGSDYINASYVSGYLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDVQIDWTIRDLKIERHGDCMAIRQCNFTAWPEHGVPESSAALVHFVKLVRASRAHDTTPMVVHCSAGVGRTGVFIALDHLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCVLDLLSSKGGNPPVCFVNYAALQKMDSLDAMEGDVELEWEETTM", "length": 2327, "header": "tr|A0A5G2QWE7-1|A0A5G2QWE7_PIG Isoform 1 of Phosphatidylinositol phosphatase PTPRQ OS=Sus scrofa OX=9823 GN=PTPRQ PE=3 SV=1 CANONICAL=A0A5G2QWE7-1" }, "isoforms": [ { "isoform_ac": "A0A287ASE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7/entry#A0A287ASE8-1", "sequence": { "sequence": "MDFLIIFLLLFIGTSETQVDVSSAVPGTRYNVAISSISATTYSSPVSRTVTTNVTKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYIVKYKEVCPWMQAAYTQVRTKPDSLEVLLTNLNPGTTYEIKVAAENSAGLGVFSDPFLFQTAESAPGKVVNLTVEAFNDSAVNLIWYLPRQPNGKITSFKISVKHARSGIVVKDVSIRVEDLLTGKLPACNENNESFLWSTTSPAPMLDRVTPPPRTTHSSSVLARSKMSSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDSTIVRTPESVPEGPPQNCLTGNITGKSFSMSWDPPSTVTGKFSYRVELYGPSGRILDNSTKDLKFAFTNLTPFTMYDVYVAAETSAGIGPKSNISVFTPPDVPGAVFDLQVADVEATEVRITWKKPRQPNGIINRYRVKVLASETGVILENTLLTGRDEYINHPMAPETVNIVESMTGLFEGSAEMSSDLYSLASVIYNIHPHNFPARSGAEDQPSIVGTTRSQYIADIAAEQLSYVIRRLVPFTEHMISVSAFTIMGEGPPTALSVRTREQVPSSIQVINYKNISSSSILLFWDPPEYPNGKITHYTIYAMELDTNRAFQMTTVDNSFLITGLKKYTKYKMRVAASTNVGESSLSEANDIFVRTPEDEPESSPRDVEVIDVSAREISLKWSPPEKPNGIIVAYEVLCKNTDTLVTKNTSTTNITLGGLKPYTRYNISVRSYTRFGHGSQLSSLLSVSTSETAPDSAPENITYRNISSGEIELSFLPPNSPNGIIQKYTIYLKKSDGNEERTINTSSLTQSIKGLKKYTQYMIEVSASTLSGEGVRSLPISVLTEEDAPDSPPQDFSVKQLSGVMVKLSWQPPLEPNGIILYYTVYVWDVSSLKTVNVTETSLELSDLDYDSEYSAYVTASTRFGDGKRRSSIIHFRTPEGAPSDPPKDVHYANLSSSSIVLFWKPPSKPNGIIQYYSVHYRNTSGTFMQNFTLHEVTNDFDNMTVSAIIDKLAIFSYYTFWVTASTSVGNGNKSSDIVQVYTDQDTPEGLVGNLTYESMSSTAVNVSWGPPSQPNGLVFYYVSLSSEQTPRHVRPLLVTYERSVYFDNLEKYTDYILEITPSTEKGFSDTYTAQLHIKTEEDVPETSPIINTFKNLSSTSVLLSWDPPVKPNGAIISYDLTLQGPRENYSFVTSDNYLILEELSPFTLYSFFAAARTVKGLGPSSVLLFYTDESVPLAPPQNLTLINYTSDLVWLKWSPSPVPGGIVKLYSLKIHEHETDTIFYKNISGLQTEAQVVGLEPVSTYSVSISAFTKVGNGNQFSNVVKFTTQESVPDVVQNIQCVATSWQSALVKWDPPRKANGIITHYLITVEKNATKVFPQDHMHTFMKLFANTSYVFKIRASTSAGEGDERTCNVSTLPETVPSVPTNITFANIRSTSATLTWMRPDSIFGYFQNYKITTQLRAQTCREWESEGCVEHQKIQYLYEADLTEETIYGLKKFRWYRFQVAASTNAGYGNASDWISTQTLPGPPDGPPENVLVVATSPFSINISWSEPAVITGPTFYLIDVQSVDSDEFNISLIKSNEENKTIEIKDLKIFTRYSVVITAFTGNISAAYGEGKSSAKVIVTTLESVPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTDTSVVAVLEGLKGGYTYNISVYAINSAGAGPKVQMRITMDIKAPARPKTKPTPIYDATGKLLVTSTTITIRMPICYYSDDHGPIKNVQVLVAEAGAQHDGNVTKWYDAYFNKPRPYFTNEGFPNPPCTEGKTKFSGNEEIYIIGADNACMIPGNEDKICNGPLKPKKQYLFKFRATNIMGQFTDSDYSDPVKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPRDAEIIDTKFKLDQLITVADLELKDERLTRLLSYRKSIKPISKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIADASIPGSDYINASYVSGYLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDVQIDWTIRDLKIERHGDCMAIRQCNFTAWPEHGVPESSAALVHFVKLVRASRAHDTTPMVVHCSAGVGRTGVFIALDHLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCVLDLLSSKGGNPPVCFVNYAALQKMDSLDAMEGDVELEWEETTM", "length": 2299, "header": "tr|A0A287ASE8-1|A0A5G2QWE7_PIG Computationally mapped isoform of Phosphatidylinositol phosphatase PTPRQ OS=Sus scrofa OX=9823 GN=PTPRQ PE=3 SV=2 CANONICAL=A0A5G2QWE7-1" }, "locus": { "chromosome": "5", "start_pos": 101023303, "end_pos": 100787888, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039234.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039234.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046835.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046835.2" } ] } }, { "isoform_ac": "A0A5G2QWE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7/entry#A0A5G2QWE7-1", "sequence": { "sequence": "VKKVATKPEKRKKRKALRISAPSFSLHWSLPSGHVDLVPDSGFVTITLLGGGEYQVDVSSAVPGTRYNVAISSISATTYSSPVSRTVTTNVTKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYIVKYKEVCPWMQAAYTQVRTKPDSLEVLLTNLNPGTTYEIKVAAENSAGLGVFSDPFLFQTAESAPGKVVNLTVEAFNDSAVNLIWYLPRQPNGKITSFKISVKHARSGIVVKDVSIRVEDLLTGKLPACNENNESFLWSTTSPAPMLDRVTPPPRTTHSSSVLARSKMSSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDSTIVRTPESVPEGPPQNCLTGNITGKSFSMSWDPPSTVTGKFSYRVELYGPSGRILDNSTKDLKFAFTNLTPFTMYDVYVAAETSAGIGPKSNISVFTPPDVPGAVFDLQVADVEATEVRITWKKPRQPNGIINRYRVKVLASETGVILENTLLTGRDEYINHPMAPETVNIVESMTGLFEGSAEMSSDLYSLASVIYNIHPHNFPARSGAEDQPSIVGTTRSQYIADIAAEQLSYVIRRLVPFTEHMISVSAFTIMGEGPPTALSVRTREQVPSSIQVINYKNISSSSILLFWDPPEYPNGKITHYTIYAMELDTNRAFQMTTVDNSFLITGLKKYTKYKMRVAASTNVGESSLSEANDIFVRTPEDEPESSPRDVEVIDVSAREISLKWSPPEKPNGIIVAYEVLCKNTDTLVTKNTSTTNITLGGLKPYTRYNISVRSYTRFGHGSQLSSLLSVSTSETAPDSAPENITYRNISSGEIELSFLPPNSPNGIIQKYTIYLKKSDGNEERTINTSSLTQSIKGLKKYTQYMIEVSASTLSGEGVRSLPISVLTEEDAPDSPPQDFSVKQLSGVMVKLSWQPPLEPNGIILYYTVYVWDVSSLKTVNVTETSLELSDLDYDSEYSAYVTASTRFGDGKRRSSIIHFRTPEGAPSDPPKDVHYANLSSSSIVLFWKPPSKPNGIIQYYSVHYRNTSGTFMQNFTLHEVTNDFDNMTVSAIIDKLAIFSYYTFWVTASTSVGNGNKSSDIVQVYTDQDTPEGLVGNLTYESMSSTAVNVSWGPPSQPNGLVFYYVSLSSEQTPRHVRPLLVTYERSVYFDNLEKYTDYILEITPSTEKGFSDTYTAQLHIKTEEDVPETSPIINTFKNLSSTSVLLSWDPPVKPNGAIISYDLTLQGPRENYSFVTSDNYLILEELSPFTLYSFFAAARTVKGLGPSSVLLFYTDESVPLAPPQNLTLINYTSDLVWLKWSPSPVPGGIVKLYSLKIHEHETDTIFYKNISGLQTEAQVVGLEPVSTYSVSISAFTKVGNGNQFSNVVKFTTQESVPDVVQNIQCVATSWQSALVKWDPPRKANGIITHYLITVEKNATKVFPQDHMHTFMKLFANTSYVFKIRASTSAGEGDERTCNVSTLPETVPSVPTNITFANIRSTSATLTWMRPDSIFGYFQNYKITTQLRAQTCREWESEGCVEHQKIQYLYEADLTEETIYGLKKFRWYRFQVAASTNAGYGNASDWISTQTLPGPPDGPPENVLVVATSPFSINISWSEPAVITGPTFYLIDVQSVDSDEFNISLIKSNEENKTIEIKDLKIFTRYSVVITAFTGNISAAYGEGKSSAKVIVTTLESVPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTDTSVVAVLEGLKGGYTYNISVYAINSAGAGPKVQMRITMDIKAPARPKTKPTPIYDATGKLLVTSTTITIRMPICYYSDDHGPIKNVQVLVAEAGAQHDGNVTKWYDAYFNKPRPYFTNEGFPNPPCTEGKTKFSGNEEIYIIGADNACMIPGNEDKICNGPLKPKKQYLFKFRATNIMGQFTDSDYSDPVKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPRDAEIIDTKFKLDQLITVADLELKDERLTRPISKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIADASIPGSDYINASYVSGYLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDVQIDWTIRDLKIERHGDCMAIRQCNFTAWPEHGVPESSAALVHFVKLVRASRAHDTTPMVVHCSAGVGRTGVFIALDHLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCVLDLLSSKGGNPPVCFVNYAALQKMDSLDAMEGDVELEWEETTM", "length": 2327, "header": "tr|A0A5G2QWE7-1|A0A5G2QWE7_PIG Isoform 1 of Phosphatidylinositol phosphatase PTPRQ OS=Sus scrofa OX=9823 GN=PTPRQ PE=3 SV=1 CANONICAL=A0A5G2QWE7-1" }, "locus": { "chromosome": "5", "start_pos": 101033334, "end_pos": 100787888, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085511.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085511.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069274.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069274.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ASE8", "url": "https://www.uniprot.org/uniprotkb/A0A287ASE8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y8L5-1", "protein_name": "Phosphatidylinositol phosphatase PTPRQ", "gene_name": "PTPRQ", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGQAILLLLLLQCLLQVSECLVCDQVRKPSRAVLLEWTEFPKGEHAEYYIVTYQLTDAFNQKNIKNISEVEQKPIGTTVLLEESKHYDITIESLKNGQIRSVKTFKTRGISENDFKILVTATTVSFNLSTMTKEFAVSVSLNDSSQIIPKNHGFFVWNDLTPGTLYTFEFTFDQLHLEFINVSQSLEVQAETGTCSKGWLAFQSSCYRMSKESKPWKVAQQTCENSSQEAHLLNIGSEEERGFILSYLQTVSHIVMLWTGLNDLKEESQLLWTDGSHYSLKANVSSLSMLPANEADCYALQRDPTGPDYFFMGFFCFIQLPYICEYELPVMPENTIFTVFDVKTTEVEFIWSYMDIWLKSGFALIMKYYSDHLKPQSLSLPANTTQAKIVQLCPGLCYRFLLVARNPEGAQAVLSPILKVETRPLHSPKLETTYVSSAEIHLKWKPPQHSSCAHFHYYLINILDSETSVWEQLPVEKNKTSTVMGNRKPYHQYQIYLQNVAEKGTQSCHEKPILITTAVSPPIAVFIQPEDVQEESVILHWKLSQEGQESYIQVKPSTDVGETKKFLVNNTEEFKIDLLIPGMTYEIAVASVNNGNMSELKTVQCTLKPKPVQIVVPYMLYSNAAVLFVRMPDTGVFDGIYVTTNGGPNATFSLKSDGKLTVENLTPGTEYDFCVFTKSREMLSSSYRVTGVKTCLAAPLNIREGNVTDTSVQIAWDRAEGDFQQYEVTCTNCASAFRVQKVKQETATFSNLVPGKLYSFTVRTEKEGFRDSVLVAKETETVPSAVKYLNYSRDSESITVTWPPAQNKFDGYVLSIKSKIFNKENMLSSGVRMYKAECLLPGTDFLISIVTTSGLKRSHPTFLKISTCPDPPSDLQVLGQEENTVYLSWKLPRGGFDKFQLSYCLMNNEKPFTRTVYDSRTVVKNLAPGMEYTFQLRTIKGWDSSVAVEKNVITKPAGICNLALKMVNTSSATLMWNPTKTNFTSYKASLSNSTFISKFMIPGAVSKFSVTNLTAGGIYNFTLQRLQGNIEGSPSFLEIVAEPAKPEGLKFFNVSSNSFSLYWRLPYGHVDRFCVDLIPDHGSVVISDLGVREYQADFYNTTPGTTYNVTVSTVSSSTYSSPASRTVTTNVTNPGPPAFLAGERVGSAGILLSWNTPQHPNGRILSYIVKYKEVCPWMQTAYTQVTSKPDSLEVLLTNLNPGTTYEIKVAAENSAGVGVFSAPFLFQTAESAPGKVVNLTVEALNYSAVNLIWFLPRQPNGKITSFKISVKHARSGIVVKDVLVKVEDLLSGRLPECNDNSESFLWSTTTPSTTFGKSTIPSSTTVTASTEASSQMSAVWNEPISFVITNLRPYTTYLFEVSAVNTEAGYIDSTIVRTPESVPEDPPQNFAKVNITSKSFSVMWDPPTIVTGKFSYRVELYGPSGHILDNSTKDLKFVFHNLVPFTMYDVYVGAETSAGVGPKTNLTVFTPSDVPGAVSDLHLVEVEATYIKIVWRKPQQPNGIITQYRVKVHVQEKEVTLENIILIGKNKHLIDSLEPYMINENIEPSPTWNSIETANELYEGSGEMFSSIQTVSPVILTTVSDDHLPAINGAAELHSTLDDQYATDILGEELSYIIKGLVPFTDYTISVSAFTAIGEGPPSVLTVRTREQVPSSVQSISYKNISSSSVLLYWDPPANPNGKIIHYTVYAMELDTKRAFHTTTSNNSLLMTGLKKYTNYKMRVAASTVIGESALSEENDIFVRTPEDEPDSPPQNVEIINVTATEINLKWLPPEQPNGLITHYEVLYSDSSDLFVRNTSSTNISLTEMMPYTLYNISVRAFTRLGHGNQSSFPLLVRTSETVPNSAPENITYWNISSTEIELSFFPPSIPNGIIQTYTIYLKRINGTEERVINTTHLVLRITDLKKYTEYMIEVSASTMLGEGLRSAPLHILTDEDAPSSPPESLSVKQLSGVTVKLSWKPPLEPNGIILYYTVYVWNKTSKRSVNVTETSLEFTDLENNSEYSAYVAASTRFGDGNIKSDTIIFRTSEGAPGDPPKDIVYKNLTSTSIMLFWSPPQKPNGNIRYYSVYFRNDSGIFIQNFTSHDNDSDVNMSPSAVLDDLAKYSHYTLWLTASTAVGDGNKTSEIIDVYTDQDIPDGPVENLVYQNISSSSVNVSWLPPSQPNGLVFFHVSLSLLQLGTNKILSFLTYNTSIIFDNLEKYTDYILKITPATDKGSSELHALSLHIRTDEDVPESAPIIKTFSNLSTTSVMLSWDPPVKPSGIIISYDLNLFGSEKNISFSTTNNFIILEDLVPSTLYSIYTAARTMKGSGPSSVLHFYTDESVPLAPPQNLTITNYTADSVWLKWEPSPQPNGVITRYNLKIYQNDTEKIFYQNISGSNNEAKLDGLKPFSTYFISVSAFTKLGNGNQFSNAVQFTTMESVPDVVQNVHCIATSWESIFMQWEPPASSNGVITYYIVTVEGSSTNFSSDTTLHTFQNLLSNISYQFKIKAATSAGDGEEQICNASTLPEEVPSAPRDIVFSNVQSTSVTLNWRSPKSIPGYFQNYKITTQLQSIYCSNWETKECIEDEIHQYLYEKGVNAQIEETVYGLKKYRWYRFAVAASTNAGYGSSSPWISTQTLPGSPDGPPENVTVLATSPHSINISWSEPVVITGPMCYLIDITSVDNENYKAQFLRTNDEGKILEISDLKAFTRYSVVIIAFTGDVNAAAIEGKASSPVIVSTFEAVPEDPPNNVTFQKIPDEVTKFQVTFVPPSEPNGNIQVYQAMVYNEDDPAAIRIHNLSVIDKTDQSVTAMIEGLKGGHTYNVSVYAINGAGAGPKIQLKITMDIKEPPRPKKKPAPVYDTNGALLVTATTITIRMPVCYYSDDHGPIKKIQVLVVEAGAQHDGNVTKWHDAYFNRPRPYFTNEGFPNPPCIEGKEDLSGKEEIYVIGADTTCMISGSQDKICNGPLKPRKQYLFKFRATNVKGQFTDSDYSDPVKTLGEGRSGGSVEVILAVTLCILSVVLLVAAVYAFARIRQKQKEGGTYSPRDAEIIDTKFKLDQLITVADLELKDERFTRYSSFFFRRKEIFVIQLLSYRKSIKPISKKSFLQHVEELCTNNNLKFQEEFSELPKFLEDLASTDADLPWNRSKNRFPNIKPYNNNRVKLMPDAGIPGSDYINASYVSGYLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLVEDIQIDWTIRDLKIERHGDCMMVRQCNFTSWPEHGVPETTAPIIHFVKLIRASRAHDNTPMVVHCSAGVGRTGVYIALDHLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCVLDLLTSRGSSQPICFVNYSALQKMDSLDAMEGDVELEWEETTM", "length": 3401 }, "evidence": [ { "id": "A0A5G2QWE7", "url": "https://omabrowser.org/oma/group/A0A5G2QWE7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O88488-1", "protein_name": "Phosphatidylinositol phosphatase PTPRQ", "gene_name": "Ptprq", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMDFHFSFLFLLIGTSESQVDVSSSFDGTGYDITLSSVSATTYSSPVSRTLATNVTKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYVVKYKEVCPWMQTAYTRARAKPDSLEVLLTNLNPGTTYEIKVAAENNAGIGVFSDPFLFQTAESAPGKVVNLTVEALNYSAVNLIWYLPRQPNGKITSFKISVKHARSGIVVKDVSLRVEDILSGKLPECNENSESFLWSTTSPSPTLGRVTPTVRTTQSSSTAARSKISSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDSTIVRTPESVPEGPPQNCIMGNVTGKAFSISWDPPTIVTGKFSYRVELYGPSGRILDNSTKDLRFAFTHLTPFTMYDVYVAAETSAGVGPKSNLSVFTPPDVPGAVFDLQIAEVEATEIRITWRKPRQPNGIISQYRVKVSVLETGVVLENTLLTGQDESISNPMSPEIMNLVDPMIGFYEGSGEMSSDLHSPASFIYNSHPHNDFPASTRAEEQSSPVVTTRNQYMTDITAEQLSYVVRRLVPFTEHTISVSAFTIMGEGPPTVLTVRTREQVPSSIQIINYKNISSSSILLYWDPPEYPNGKITHYTIYATELDTNRAFQMTTVDNSFLITGLKKYTRYKMRVAASTHVGESSLSEENDIFVRTPEDEPESSPQDVQVTGVSPSELRLKWSPPEKPNGIIIAYEVLYQNADTLFVKNTSTTDIIISDLKPYTLYNISIRSYTRLGHGNQSSSLLSVRTSETVPDSAPENITYKNISSGEIEISFLPPRSPNGIIQKYTIYLKRSNSHEARTINTTSLTQTIGGLKKYTHYVIEVSASTLKGEGIRSRPISILTEEDAPDSPPQNFSVKQLSGVTVMLSWQPPLEPNGIILYYTVYVWDKSSLRAINATEASLVLSDLDYNVDYGACVTASTRFGDGNARSSIINFRTPEGEPSDPPNDVHYVNLSSSSIILFWTPPVKPNGIIQYYSVYYQNTSGTFVQNFTLLQVTKESDNVTVSARIYRLAIFSYYTFWLTASTSVGNGNKSSDIIHVYTDQDIPEGPVGNLTFESISSTAIHVSWEPPSQPNGLVFYYLSLNLQQSPPRHMIPPLVTYENSIDFDDLEKYTDYIFKITPSTEKGFSETYTTQLHIKTEEDVPDTPPIINTFKNLSSTSILLSWDPPLKPNGAILGYHLTLQGPHANHTFVTSGNHIVLEELSPFTLYSFFAAARTMKGLGPSSILFFYTDESAPLAPPQNLTLINYTSDFVWLTWSPSPLPGGIVKVYSFKIHEHETDTVFYKNISGLQTDAKLEGLEPVSTYSVSVSAFTKVGNGNQYSNVVEFTTQESVPEAVRNIECVARDWQSVSVRWDPPRKTNGIIIHYMITVGGNSTKVSPRDPTYTFTKLLPNTSYVFEVRASTSAGEGNESRCDISTLPETVPSAPTNVAFSNVQSTSATLTWTKPDTIFGYFQNYKITTQLRAQKCREWEPEECIEHQKDQYLYEANQTEETVHGLKKFRWYRFQVAASTNVGYSNASEWISTQTLPGPPDGPPENVHVVATSPFGINISWSEPAVITGPTFYLIDVKSVDDDDFNISFLKSNEENKTTEINNLEVFTRYSVVITAFVGNVSRAYTDGKSSAEVIITTLESVPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIRVYQALVYREDDPTAVQIHNFSIIQKTDTSIIAMLEGLKGGHTYNISVYAINSAGAGPKVQMRITMDIKAPARPKSKPIPIRDATGKLLVTSTTITIRMPICYYNDDHGPIRNVQVLVAETGAQQDGNVTKWYDAYFNKARPYFTNEGFPNPPCIEGKTKFSGNEEIYVIGADNACMIPGNEEKICNGPLKPKKQYLFKFRATNVMGQFTDSEYSDPIKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFVRIRQKQKEGGTYSPRDAEIIDTKFKLDQLITVADLELKDERLTRLLSYRKSIKPISKKSFLQHVEELCTNSNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIADVSLPGSDYINASYVSGYLCPNEFIATQGPLPGTVGDFWRMVWETRTKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDIQIDWTIRDLKIERHGDCMTVRQCNFTGWPEHGVPENTTPLIHFVKLVRTSRAHDTTPMVVHCSAGVGRTGVFIALDHLTQHINNHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKGGHQPVCFVNYSTLQKMDSLDAMEGDVELEWEETTM", "length": 2302 }, "evidence": [ { "id": "A0A5G2QWE7", "url": "https://omabrowser.org/oma/group/A0A5G2QWE7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C5E4-1", "protein_name": "Phosphatidylinositol phosphatase PTPRQ", "gene_name": "Ptprq", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFLFFFLFSLIGTSESQVDVSGSFDDTVYDITLSSISATTYSSPVSRTLATNVSKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYVVKYKEVCPWMQTAYTRVRAKPDSLEVLLTNLNPGTTYEIKVAAENSAGIGVFSDPFLFQTAESAPGKVVNLTVEALNYSAVNLIWYLPRQPNGKITSFKISVKHARSGIVVKDVSIKVEDLLSGKLPECNENSDSFLWSTTSPSPTLSRATPPLRTTHLSNTLARNKISSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDSTIVRTPESVPEGPPQNCITGNVTGKAFSISWDPPAIVTGKFSYRVELYGPTGRILDNSTKDLRFVFTHLTPFTMYDVYVAAETSAGVGPKSNLSVFTPPDVPGAVFDLQIVEVEATEIRVSWRKPRQPNGIISQYRVKVSVLESGVILENTLLTGQDEYINNPMTPEIMNLVDPMIGFYEGSGEMSSDLHSLASFIYNSHPHDFPARTRVEDQRSPVVATRNQYMTDIAAEHLSYVIRRLVPFTEHTISVSAFTVMGEGPPTVLTVRTREQVPSSIQIINYKNISSSSILLYWDPPEYPNGKITHYTIYAMELDTNRAFQMTTVDNSFLITGLKKYTRYKMRVAASTHVGESSLSEENDLFVRTPEDEPESSPQDVKVTDVSPSELSLTWSPPEKPNGIIIAYEVFYQNADALFVKNTSTTNITLSDLKPYTLYNISIQSYTRLGHGNQSSSLLSVRTSETVPDSAPENITYKNISSEEIEIFFLPPRSPNGIIQKYTIYLKRSNSHEARTIETTSLTLTIGGLKKYTHYVIEVSASTLKGEGVRSMPISILTEEDAPDSPPQNFSVKQLSGVTVMLSWQPPLEPNGIILYYTVYVWDKVSLKTINATEVSLELSDLDYHADYSAYVTASTRFGDGKTRSSVINFRTPEGEPSDPPKDVHYVNLSSSSIILFWTPPVKPNGIIQYYSVYYQNTSSTFVQNFTLLEVTQEPGNVTVSARIYKLAVFSYYTFWLTASTLVGNGNKSSDVIHVYTDQDIPEGGVGNLTYESLSSTAINVSWTPPSQPNGLVFYYVSLNLQQSPPRHRRPPLTTYENSIYFDNLEKYTDYIFKITPSTEKGFSETYTAQLHIKTEEDVPDTPPIINTFKNLSSTSILLSWDPPLKPNGAILSYHLTLQGTHANRTFVTSGNHIVLEELSPFTLYSFLAAARTMKGLGPSSILFFYTDESAPLAPPQNLTLINYTSDFVWLTWSPSPLPGGIVKVYSFKIHEHETDTVFYKNISGFQTDAKLAGLEPVSTYSISVSAFTKVGNGNQFSNVVKFTTQESVPDAVQNIACVARDWQSVSVMWDPPRKANGIIIHYMITVEGNSTKVSPRDPMYTFTKLLANTSYIFEVRASTSAGEGNESQCNVSTLPETVPSVPTNTAFSNVQSTSVTLRWIKPDTILGYFQNYKITTQLRAQKCREWEPEECVEHQEVQYLYEANQTEDTVRGLKKFQWYRFQVAASTNAGYGNASSWISTQTLPGPPDGPPENVRVVATSPFGINISWNEPAIITGPTFYLIDVKSVDNDNFNISFVKSNEENKTTEINDLEVFTRYSVVITAFVGNVSGAYTDGKSSAEVIITTLESVPKDPPNNMTFQKIPDEVTKFQLSFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTDTSVIAMLEGLKGGHTYNISVYAINSAGAGPKVQMRITMDIKAPARPKTKPIPIHDATGKLLVTSTTITIRMPICYYNDDHGPIRNVQVLVAEAGAQQDGNVTKWYDAYFNKARPYFTNEGFPNPPCIEGKTKFSGNEEIYVIGADNACMIPGNEEKICNGPLKPKKQYLFKFRATNVMGQFTDSEYSDPIKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPRDAEIIDTKFKLDQLITVADLELKDERLTRLLSYRKSIKPVSKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIADVSIPGSDYINASYVSGYLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDILITKLMEDIQIDWTIRDLKIERHGDCMTVRQCNFTGWPEHGVPENTTPLIHFVKLVRTSRAHDATPMVVHCSAGVGRTGVFIALDHLTQHIHDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKGGHQPVCFVNYSTLQKMDSLDAMEGDVELEWEETTM", "length": 2300 }, "evidence": [ { "id": "A0A5G2QWE7", "url": "https://omabrowser.org/oma/group/A0A5G2QWE7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UMZ3-1", "protein_name": "Phosphatidylinositol phosphatase PTPRQ", "gene_name": "PTPRQ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKVPIKPEQPEKLRAFNISTHSFSLHWSLPSGHVERYQVDLVPDSGFVTIRDLGGGEYQVDVSNVVPGTRYDITISSISTTYTSPVTRIVTTNVTKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYIVKYKEVCPWMQTVYTQVRSKPDSLEVLLTNLNPGTTYEIKVAAENSAGIGVFSDPFLFQTAESAPGKVVNLTVEAYNASAVKLIWYLPRQPNGKITSFKISVKHARSGIVVKDVSIRVEDILTGKLPECNENSESFLWSTASPSPTLGRVTPPSRTTHSSSTLTQNEISSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDSTIVRTPESVPEGPPQNCVTGNITGKSFSILWDPPTIVTGKFSYRVELYGPSGRILDNSTKDLKFAFTNLTPFTMYDVYIAAETSAGTGPKSNISVFTPPDVPGAVFDLQLAEVESTQVRITWKKPRQPNGIINQYRVKVLVPETGIILENTLLTGNNEYINDPMAPEIVNIVEPMVGLYEGSAEMSSDLHSLATFIYNSHPDKNFPARNRAEDQTSPVVTTRNQYITDIAAEQLSYVIRRLVPFTEHMISVSAFTIMGEGPPTVLSVRTRQQVPSSIKIINYKNISSSSILLYWDPPEYPNGKITHYTIYAMELDTNRAFQITTIDNSFLITGLKKYTKYKMRVAASTHVGESSLSEENDIFVRTSEDEPESSPQDVEVIDVTADEIRLKWSPPEKPNGIIIAYEVLYKNIDTLYMKNTSTTDIILRNLRPHTLYNISVRSYTRFGHGNQVSSLLSVRTSETVPDSAPENITYKNISSGEIELSFLPPSSPNGIIKKYTIYLKRSNGNEERTINTTSLTQNIKVLKKYTQYIIEVSASTLKGEGVRSAPISILTEEDAPDSPPQDFSVKQLSGVTVKLSWQPPLEPNGIILYYTVYVWNRSSLKTINVTETSLELSDLDYNVEYSAYVTASTRFGDGKTRSNIISFQTPEGAPSDPPKDVYYANLSSSSIILFWTPPSKPNGIIQYYSVYYRNTSGTFMQNFTLHEVTNDFDNMTVSTIIDKLTIFSYYTFWLTASTSVGNGNKSSDIIEVYTDQDIPEGFVGNLTYESISSTAINVSWVPPAQPNGLVFYYVSLILQQTPRHVRPPLVTYERSIYFDNLEKYTDYILKITPSTEKGFSDTYTAQLYIKTEEDVPETSPIINTFKNLSSTSVLLSWDPPVKPNGAIISYDLTLQGPNENYSFITSDNYIILEELSPFTLYSFFAAARTRKGLGPSSILFFYTDESVPLAPPQNLTLINCTSDFVWLKWSPSPLPGGIVKVYSFKIHEHETDTIYYKNISGFKTEAKLVGLEPVSTYSIRVSAFTKVGNGNQFSNVVKFTTQESVPDVVQNMQCMATSWQSVLVKWDPPKKANGIITQYMVTVERNSTKVSPQDHMYTFIKLLANTSYVFKVRASTSAGEGDESTCHVSTLPETVPSVPTNIAFSDVQSTSATLTWIRPDTILGYFQNYKITTQLRAQKCKEWESEECVEYQKIQYLYEAHLTEETVYGLKKFRWYRFQVAASTNAGYGNASNWISTKTLPGPPDGPPENVHVVATSPFSISISWSEPAVITGPTCYLIDVKSVDNDEFNISFIKSNEENKTIEIKDLEIFTRYSVVITAFTGNISAAYVEGKSSAEMIVTTLESAPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTNTFVIAMLEGLKGGHTYNISVYAVNSAGAGPKVPMRITMDIKAPARPKTKPTPIYDATGKLLVTSTTITIRMPICYYSDDHGPIKNVQVLVTETGAQHDGNVTKWYDAYFNKARPYFTNEGFPNPPCTEGKTKFSGNEEIYIIGADNACMIPGNEDKICNGPLKPKKQYLFKFRATNIMGQFTDSDYSDPVKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPQDAEIIDTKLKLDQLITVADLELKDERLTRPISKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIADASVPGSDYINASYISGYLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDVQIDWTIRDLKIERHGDCMTVRQCNFTAWPEHGVPENSAPLIHFVKLVRASRAHDTTPMIVHCSAGVGRTGVFIALDHLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKGSNQPICFVNYSALQKMDSLDAMEGDVELEWEETTM", "length": 2332 }, "evidence": [ { "id": "A0A5G2QWE7", "url": "https://omabrowser.org/oma/group/A0A5G2QWE7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity", "id": "GO:0016314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016314", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity", "id": "GO:0052629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052629", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "id": "GO:0034485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034485", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of sound", "id": "GO:0050910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050910", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ], "pmid": "" }, { "name": "basal plasma membrane", "id": "GO:0009925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009925", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ], "pmid": "" }, { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ], "pmid": "" }, { "name": "stereocilium base", "id": "GO:0120044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120044", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1025, "end_pos": 1027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1033, "end_pos": 1035, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1045, "end_pos": 1047, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1075, "end_pos": 1077, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1096, "end_pos": 1098, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1108, "end_pos": 1110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1198, "end_pos": 1200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1231, "end_pos": 1233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1285, "end_pos": 1287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1290, "end_pos": 1292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1329, "end_pos": 1331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1417, "end_pos": 1419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1436, "end_pos": 1438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1458, "end_pos": 1460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1472, "end_pos": 1474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1561, "end_pos": 1563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1593, "end_pos": 1595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1621, "end_pos": 1623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1631, "end_pos": 1633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1655, "end_pos": 1657, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1684, "end_pos": 1686, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1731, "end_pos": 1733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1756, "end_pos": 1758, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1839, "end_pos": 1841, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2087, "end_pos": 2089, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2190, "end_pos": 2192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 750, "end_pos": 752, "annotation": "n_glycosylation_sequon" }, { "start_pos": 755, "end_pos": 757, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" }, { "start_pos": 802, "end_pos": 804, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 846, "end_pos": 848, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" }, { "start_pos": 939, "end_pos": 941, "annotation": "n_glycosylation_sequon" }, { "start_pos": 996, "end_pos": 998, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25017", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "25017", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25017" } ] }, { "id": "25528", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "25528", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25528" } ] }, { "id": "32955", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "32955", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32955" } ] }, { "id": "39019", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "39019", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/39019" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 191, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QWE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 2207, "end_pos": 2278, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QWE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE7" }, { "id": "PS50055", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50055" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 2031, "end_pos": 2287, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1025, "end_pos": 1027 }, { "start_pos": 1033, "end_pos": 1035 }, { "start_pos": 1045, "end_pos": 1047 }, { "start_pos": 1075, "end_pos": 1077 }, { "start_pos": 1096, "end_pos": 1098 }, { "start_pos": 1108, "end_pos": 1110 }, { "start_pos": 1198, "end_pos": 1200 }, { "start_pos": 1231, "end_pos": 1233 }, { "start_pos": 1285, "end_pos": 1287 }, { "start_pos": 1290, "end_pos": 1292 }, { "start_pos": 1329, "end_pos": 1331 }, { "start_pos": 1417, "end_pos": 1419 }, { "start_pos": 1436, "end_pos": 1438 }, { "start_pos": 1458, "end_pos": 1460 }, { "start_pos": 1472, "end_pos": 1474 }, { "start_pos": 1561, "end_pos": 1563 }, { "start_pos": 1593, "end_pos": 1595 }, { "start_pos": 1621, "end_pos": 1623 }, { "start_pos": 1631, "end_pos": 1633 }, { "start_pos": 1655, "end_pos": 1657 }, { "start_pos": 1684, "end_pos": 1686 }, { "start_pos": 1731, "end_pos": 1733 }, { "start_pos": 1756, "end_pos": 1758 }, { "start_pos": 1839, "end_pos": 1841 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 2087, "end_pos": 2089 }, { "start_pos": 2190, "end_pos": 2192 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 616, "end_pos": 618 }, { "start_pos": 750, "end_pos": 752 }, { "start_pos": 755, "end_pos": 757 }, { "start_pos": 768, "end_pos": 770 }, { "start_pos": 802, "end_pos": 804 }, { "start_pos": 807, "end_pos": 809 }, { "start_pos": 846, "end_pos": 848 }, { "start_pos": 90, "end_pos": 92 }, { "start_pos": 939, "end_pos": 941 }, { "start_pos": 996, "end_pos": 998 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2A2-1", "uniprot_ac": "A0A5G2R2A2", "uniprot_id": "A0A5G2R2A2_PIG", "mass": { "chemical_mass": 60929.0, "monoisotopic_mass": 60929.0 }, "refseq": {}, "gene_names": [ { "name": "TCTN1", "type": "recommended", "evidence": [ { "id": "A0A5G2R2A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2" } ] } ], "protein_names": [ { "name": "Tectonic family member 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R2A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TCTN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2", "locus": { "chromosome": "14", "start_pos": 32010185, "end_pos": 31954000, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009826", "url": "https://www.ensembl.org/id/ENSSSCG00000009826" } ] } } ], "crossref": [ { "id": "A0A5G2R2A2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2A2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009826", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009826", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100153308", "url": "https://www.ncbi.nlm.nih.gov/gene/100153308", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040354", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040354", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14611", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14611", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14611:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14611:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AUV5", "url": "https://www.uniprot.org/uniprotkb/A0A287AUV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AUV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AUV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QAI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QAI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2A2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RNM5", "url": "https://www.uniprot.org/uniprotkb/F1RNM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RNM5-1", "url": "https://www.uniprot.org/uniprotkb/F1RNM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHRVFSLFLSCCDLPTLSPRPPETPRGPRPSSGPRPTPVTDVAALCVCDLSPAQCDINCCCDPDCSSTDFSVFSACSIPVVTGDSRFCSQKAAIYSLNFTADPPQRVFKLVDQINPSMFCIHITNYKPALSFINPEVIADESNFDKMMKTSDGFSLNAESDVSFTTKPDAPNATKYEYGAHLQTSDSFLRFPSPLTSSLCTDNNPAAFLVNQAVKCTRRINLEQCEEIETLSMAYYSSPKILKVPGSGTKVPITVQSIVIQSLNKTLTRLEGIDLLKPRHVEAGHNKICINIVLKVKYSLTYTDAGEIIKADLSLLLGAVSSAMVPLQQKFDIYFIQQNTKPVPLSGNPGYGLGLPLAAGFQPRKGSGIIQTTNRYGQFTILRSTTEQDCLAIEGIRTPVLFGYNMQSGCKLRLTKTITCRLAAQKVKSLLKGQGFPDYVAPFGNSQAQDVLDWVPIHFITQTSHVKDSCQLPVALAIEVKWTKYGSLLNPQAKIVNVTANLISSSFSETHLGNERTILISTAVTFVDVSAPAEAGFRARPTINARLPFNFFFPFV", "length": 557, "header": "tr|A0A5G2R2A2-1|A0A5G2R2A2_PIG Isoform 1 of Tectonic family member 1 OS=Sus scrofa OX=9823 GN=TCTN1 PE=3 SV=1 CANONICAL=A0A5G2R2A2-1" }, "isoforms": [ { "isoform_ac": "A0A287AUV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2/entry#A0A287AUV5-1", "sequence": { "sequence": "MGPRGLPPLLLVFLGCWASVNAQAGATPVVTTEGFNSTEPAPTTLLPTLSPRPPETPRGPRPSSGPRPTPVTDVAALCVCDLSPAQCDINCCCDPDCSSTDFSVFSACSIPVVTGDSRFCSQKAAIYSLNFTADPPQRVFKLVDQINPSMFCIHITNYKPALSFINPEVIADESNFDKMMKTSDGFSLNAESDVSFTTKPDAPNATKYEYGAHLQTSDSFLRFPSPLTSSLCTDNNPAAFLVNQAVKCTRRINLEQCEEIETLSMAYYSSPKILKVPGSGTKVPITVQSIVIQSLNKTLTRLEGIDLLKPRHVEAGHNKICINIVLKVKYSLTYTDAGEIIKADLSLLLGAVSSAMVPLQQKFDIYFIQQNTKPVPLSGNPGYGLGLPLAAGFQPRKGSGIIQTTNRYGQFTILRSTTEQDCLAIEGIRTPVLFGYNMQSGCKLRLTKTITCRLAAQKVKSLLKGQGFPDYVAPFGNSQAQDVLDWVPIHFITQTSHVKDSCQLPVALAIEVKWTKYGSLLNPQAKIVNVTANLISSSFSESPHMKGCTGSSTYM", "length": 555, "header": "tr|A0A287AUV5-1|A0A5G2R2A2_PIG Computationally mapped isoform of Tectonic family member 1 OS=Sus scrofa OX=9823 GN=TCTN1 PE=3 SV=3 CANONICAL=A0A5G2R2A2-1" }, "locus": { "chromosome": "14", "start_pos": 32008315, "end_pos": 31976385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056582.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056582.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047711.3", "url": "https://www.ensembl.org/id/ENSSSCP00000047711.3" } ] } }, { "isoform_ac": "A0A5G2QAI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2/entry#A0A5G2QAI4-1", "sequence": { "sequence": "MGPRGLPPLLLVFLGCWASVNAQAGATPVVTTEGFNSTEPAPTTLLPTLSPRPPETPRGPRPSSGPRPTPVTDVAALCVCDLSPAQCDINCCCDPDCSSTDFSVFSACSIPVVKPALSFINPEVIADESNFDKMMKTSDGFSLNAESDVSFTTKPDAPNATKYEYGAHLQTSDSFLRFPSPLTSSLCTDNNPAAFLVNQAVKCTRRINLEQCEEIETLSMAYYSSPKILKVPGSGTKVPITVQSIVIQSLNKTLTRLEGIDLLKPRHVEAGHNKICINIVLKVKYSLTYTDAGEIIKADLSLLLGAVSSAMVPLQQKFDIYFIQQNTKPVPLSGNPGYGLGLPLAAGFQPRKGKTITCRLAAQKVKSLLKGQGFPDYVAPFGNSQAQDVLDWVPIHFITQTSHVKDSCQLPVALAIEVKWTKYGSLLNPQAKIVNVTANLISSSFSETHLGNERTILISTAVTFVDVSAPAEAGFRARPTINARLPFNFFFPFV", "length": 494, "header": "tr|A0A5G2QAI4-1|A0A5G2QAI4_PIG Computationally mapped isoform of Tectonic family member 1 OS=Sus scrofa OX=9823 GN=TCTN1 PE=3 SV=2 CANONICAL=A0A5G2R2A2-1" }, "locus": { "chromosome": "14", "start_pos": 32007375, "end_pos": 31976385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069829.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069829.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061016.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061016.2" } ] } }, { "isoform_ac": "A0A5G2R2A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2/entry#A0A5G2R2A2-1", "sequence": { "sequence": "MLHRVFSLFLSCCDLPTLSPRPPETPRGPRPSSGPRPTPVTDVAALCVCDLSPAQCDINCCCDPDCSSTDFSVFSACSIPVVTGDSRFCSQKAAIYSLNFTADPPQRVFKLVDQINPSMFCIHITNYKPALSFINPEVIADESNFDKMMKTSDGFSLNAESDVSFTTKPDAPNATKYEYGAHLQTSDSFLRFPSPLTSSLCTDNNPAAFLVNQAVKCTRRINLEQCEEIETLSMAYYSSPKILKVPGSGTKVPITVQSIVIQSLNKTLTRLEGIDLLKPRHVEAGHNKICINIVLKVKYSLTYTDAGEIIKADLSLLLGAVSSAMVPLQQKFDIYFIQQNTKPVPLSGNPGYGLGLPLAAGFQPRKGSGIIQTTNRYGQFTILRSTTEQDCLAIEGIRTPVLFGYNMQSGCKLRLTKTITCRLAAQKVKSLLKGQGFPDYVAPFGNSQAQDVLDWVPIHFITQTSHVKDSCQLPVALAIEVKWTKYGSLLNPQAKIVNVTANLISSSFSETHLGNERTILISTAVTFVDVSAPAEAGFRARPTINARLPFNFFFPFV", "length": 557, "header": "tr|A0A5G2R2A2-1|A0A5G2R2A2_PIG Isoform 1 of Tectonic family member 1 OS=Sus scrofa OX=9823 GN=TCTN1 PE=3 SV=1 CANONICAL=A0A5G2R2A2-1" }, "locus": { "chromosome": "14", "start_pos": 32007375, "end_pos": 31954185, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081335.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081335.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070476.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070476.1" } ] } }, { "isoform_ac": "F1RNM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2/entry#F1RNM5-1", "sequence": { "sequence": "MGPRGLPPLLLVFLGCWASVNAQAGATPVVTTEGFNSTEPAPTTLLPTLSPRPPETPRGPRPSSGPRPTPVTDVAALCVCDLSPAQCDINCCCDPDCSSTDFSVFSACSIPVVTGDSRFCSQKAAIYSLNFTADPPQRVFKLVDQINPSMFCIHITNYKPALSFINPEVIADESNFDKMMKTSDGFSLNAESDVSFTTKPDAPNATKYEYGAHLQTSDSFLRFPSPLTSSLCTDNNPAAFLVNQAVKCTRRINLEQCEEIETLSMAYYSSPKILKVPGSGTKVPITVQSIVIQSLNKTLTRLEGIDLLKPRHVEAGHNKICINIVLKQNTKPVPLSGNPGYGLGLPLAAGFQPRKGSGIIQTTNRYGQFTILRSTTEQDCLAIEGIRTPVLFGYNMQSGCKLRLTKTITCRLAAQKVKSLLKGQGFPDYVAPFGNSQAQDVLDWVPIHFITQTSHVKDSCQLPVALAIEVKWTKYGSLLNPQAKIVNVTANLISSSFSETHLGNERTILISTAVTFVDVSAPAEAGFRARPTINARLPFNFFFPFV", "length": 546, "header": "tr|F1RNM5-1|A0A5G2R2A2_PIG Computationally mapped isoform of Tectonic family member 1 OS=Sus scrofa OX=9823 GN=TCTN1 PE=3 SV=4 CANONICAL=A0A5G2R2A2-1" }, "locus": { "chromosome": "14", "start_pos": 32007375, "end_pos": 31976385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010769.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010769.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010489.5", "url": "https://www.ensembl.org/id/ENSSSCP00000010489.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 38, "start_aa": "Thr", "end_pos": 38, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr38", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AUV5", "url": "https://www.uniprot.org/uniprotkb/A0A287AUV5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2" } ], "pmid": "" }, { "name": "protein localization to ciliary transition zone", "id": "GO:1904491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904491", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2" } ], "pmid": "" }, { "name": "MKS complex", "id": "GO:0036038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036038", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2A2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 557, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2A2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2A2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2" }, { "id": "PF07773", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07773" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tectonic-1-3", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 338, "start_aa": "Ala", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R2A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A2" }, { "id": "PF25752", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25752" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tectonic-1-3 N-terminal", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 141, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 38 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 498, "end_pos": 500 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QY66-1", "uniprot_ac": "A0A5G2QY66", "uniprot_id": "A0A5G2QY66_PIG", "mass": { "chemical_mass": 75416.0, "monoisotopic_mass": 75416.0 }, "refseq": {}, "gene_names": [ { "name": "CAPN9", "type": "recommended", "evidence": [ { "id": "A0A5G2QY66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66" } ] } ], "protein_names": [ { "name": "Calpain 9", "type": "synonym", "evidence": [ { "id": "A0A5G2QY66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Calcium-regulated non-lysosomal thiol-protease.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R452", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R452#function" }, { "database": "UniProtKB", "id": "ARBA00002989", "url": "https://www.uniprot.org/uniprotkb/ARBA00002989#function" }, { "database": "UniProtKB", "id": "A0A287AXF0", "url": "https://www.uniprot.org/uniprotkb/A0A287AXF0#function" }, { "database": "UniProtKB", "id": "F1RG55", "url": "https://www.uniprot.org/uniprotkb/F1RG55#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY66", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CAPN9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66", "locus": { "chromosome": "14", "start_pos": 59582046, "end_pos": 59623376, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010182", "url": "https://www.ensembl.org/id/ENSSSCG00000010182" } ] } } ], "crossref": [ { "id": "A0A5G2QY66", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QY66", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010182", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010182", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16192", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16192", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100154688", "url": "https://www.ncbi.nlm.nih.gov/gene/100154688", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154688", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154688", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IEQTIYS", "url": "https://omabrowser.org/oma/group/IEQTIYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RG55", "url": "https://www.orthodb.org/?gene=F1RG55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183:SF385", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183:SF385", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1474228", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1474228", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AXF0", "url": "https://www.uniprot.org/uniprotkb/A0A287AXF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY66", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY66-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R452", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R452", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R452-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R452-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RG55", "url": "https://www.uniprot.org/uniprotkb/F1RG55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RG55-1", "url": "https://www.uniprot.org/uniprotkb/F1RG55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPHLYRAPGPQEPPTPKDARITHSSGQSFEELRRACLQKGVLFEDTDFPADSSSLFYSERPQIPFVWKRPGEIVKNPEFILGGATRTDICQGELGDCWLLAAIASLTLNEKALARVVPHNQSFGPGYAGIFHFQFWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAETFTTKEAPGNFYEILEKALTRGSLVGCSIDIRNAAESEARTPFGLIKGHAYTVTGVDQVNIRGQKVELIRVRNPWGQVEWTGSWSDRMAFRDFRAHFDKVEVCNLTPDALEEDAVHKWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECTFLVALMQKDRRKLKRFGANVLTIGYAIYQCPGQEGHLNKDFFRYHASQARSKTFINLREVSDRFRLPPGDYILIPSTFEPHQEADFCLRIFSEKKAITRDMDGSVDIDLPEPPKPTAPGQETEEERQFQALFKQVAGEDMEVTAEELKYVLNAVLQKKKDIKFKELSLISCKNIISLMDTSGNGKLEFSEFKVFWDKLKKWMSLFLQFDADKSGTMSSYELRSALKAAGFQLSSPLLQLIVLRYADPELQLGFDDFLNCLVRLENASRMFQALSTKNKEFIHLNINEFIVLTMNI", "length": 664, "header": "tr|A0A5G2QY66-1|A0A5G2QY66_PIG Isoform 1 of Calpain 9 OS=Sus scrofa OX=9823 GN=CAPN9 PE=3 SV=1 CANONICAL=A0A5G2QY66-1" }, "isoforms": [ { "isoform_ac": "A0A287AXF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66/entry#A0A287AXF0-1", "sequence": { "sequence": "MPHLYRAPGPQEPPTPKDARITHSSGQSFEELRRACLQKGVLFEDTDFPADSSSLFYSERPQIPFVWKRPGEIVKNPEFILGGATRTDICQGELGDCWLLAAIASLTLNEKALARVVPHNQSFGPGYAGIFHFQFWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAETFTTKEAPGNFYEILEKALTRGSLVGCSIDIRNAAESEARTPFGLIKGHAYTVTGVDQVNIRGQKVELIRVRNPWGQVEWTGSWSDSSSEWRSVGPAEQKRLCHTALDDGEFWMAFRDFRAHFDKVEVCNLTPDALEEDAVHKWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECTFLVALMQKDRRKLKRFGANVLTIGYAIYQCPGQEGHLNKDFFRYHASQARSKTFINLREVSDRFRLPPGDYILIPSTFEPHQEADFCLRIFSEKKAITRDMDGSVDIDLPEDMEVTAEELKYVLNAVLQKKKDIKFKELSLISCKNIISLMDTSGNGKLEFSEFKVFWDKLKKWMSLFLQFDADKSGTMSSYELRSALKAAGFQLSSPLLQLIVLRYADPELQLGFDDFLNCLVRLENASRMFQALSTKNKEFIHLNINEFIVLTMNI", "length": 663, "header": "tr|A0A287AXF0-1|A0A5G2QY66_PIG Computationally mapped isoform of Calpain 9 OS=Sus scrofa OX=9823 GN=CAPN9 PE=3 SV=1 CANONICAL=A0A5G2QY66-1" }, "locus": { "chromosome": "14", "start_pos": 59623317, "end_pos": 59582273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060757.2", "url": "https://www.ensembl.org/id/ENSSSCT00000060757.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048619.1", "url": "https://www.ensembl.org/id/ENSSSCP00000048619.1" } ] } }, { "isoform_ac": "A0A5G2QY66-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66/entry#A0A5G2QY66-1", "sequence": { "sequence": "MPHLYRAPGPQEPPTPKDARITHSSGQSFEELRRACLQKGVLFEDTDFPADSSSLFYSERPQIPFVWKRPGEIVKNPEFILGGATRTDICQGELGDCWLLAAIASLTLNEKALARVVPHNQSFGPGYAGIFHFQFWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAETFTTKEAPGNFYEILEKALTRGSLVGCSIDIRNAAESEARTPFGLIKGHAYTVTGVDQVNIRGQKVELIRVRNPWGQVEWTGSWSDRMAFRDFRAHFDKVEVCNLTPDALEEDAVHKWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECTFLVALMQKDRRKLKRFGANVLTIGYAIYQCPGQEGHLNKDFFRYHASQARSKTFINLREVSDRFRLPPGDYILIPSTFEPHQEADFCLRIFSEKKAITRDMDGSVDIDLPEPPKPTAPGQETEEERQFQALFKQVAGEDMEVTAEELKYVLNAVLQKKKDIKFKELSLISCKNIISLMDTSGNGKLEFSEFKVFWDKLKKWMSLFLQFDADKSGTMSSYELRSALKAAGFQLSSPLLQLIVLRYADPELQLGFDDFLNCLVRLENASRMFQALSTKNKEFIHLNINEFIVLTMNI", "length": 664, "header": "tr|A0A5G2QY66-1|A0A5G2QY66_PIG Isoform 1 of Calpain 9 OS=Sus scrofa OX=9823 GN=CAPN9 PE=3 SV=1 CANONICAL=A0A5G2QY66-1" }, "locus": { "chromosome": "14", "start_pos": 59623317, "end_pos": 59582273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087697.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087697.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069083.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069083.1" } ] } }, { "isoform_ac": "A0A5G2R452-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66/entry#A0A5G2R452-1", "sequence": { "sequence": "MPHLYRAPGPQEPPTPKDARITHSSGQSFEELRRACLQKGVLFEDTDFPADSSSLFYSERPQIPFVWKRPGFWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAETFTTKEAPGNFYEILEKALTRGSLVGCSIDIRNAAESEARTPFGLIKGHAYTVTGVDQVNIRGQKVELIRVRNPWGQVEWTGSWSDSSSEWRSVGPAEQKRLCHTALDDGEFWMAFRDFRAHFDKVEVCNLTPDALEEDAVHKWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECTFLVALMQKDRRKLKRFGANVLTIGYAIYQCPGQEGHLNKDFFRYHASQARSKTFINLREVSDRFRLPPGDYILIPSTFEPHQEADFCLRIFSEKKAITRDMDGSVDIDLPEPPKPTAPGQETEEERQFQALFKQVAGEDMEVTAEELKYVLNAVLQKKKDIKFKELSLISCKNIISLMDTSGNGKLEFSEFKVFWDKLKKWMSLFLQFDADKSGTMSSYELRSALKAAGFQLSSPLLQLIVLRYADPELQLGFDDFLNCLVRLENASRMFQALSTKNKEFIHLNINEFIVLTMNI", "length": 627, "header": "tr|A0A5G2R452-1|A0A5G2R452_PIG Computationally mapped isoform of Calpain-9 OS=Sus scrofa OX=9823 GN=CAPN9 PE=3 SV=1 CANONICAL=A0A5G2QY66-1" }, "locus": { "chromosome": "14", "start_pos": 59623317, "end_pos": 59582273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086375.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086375.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071866.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071866.1" } ] } }, { "isoform_ac": "F1RG55-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66/entry#F1RG55-1", "sequence": { "sequence": "MPHLYRAPGPQEPPTPKDARITHSSGQSFEELRRACLQKGVLFEDTDFPADSSSLFYSERPQIPFVWKRPGEIVKNPEFILGGATRTDICQGELGDCWLLAAIASLTLNEKALARVVPHNQSFGPGYAGIFHFQFWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAETFTTKEAPGNFYEILEKALTRGSLVGCSIDIRNAAESEARTPFGLIKGHAYTVTGVDQVNIRGQKVELIRVRNPWGQVEWTGSWSDSSSEWRSVGPAEQKRLCHTALDDGEFWMAFRDFRAHFDKVEVCNLTPDALEEDAVHKWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECTFLVALMQKDRRKLKRFGANVLTIGYAIYQCPGQEGHLNKDFFRYHASQARSKTFINLREVSDRFRLPPGDYILIPSTFEPHQEADFCLRIFSEKKAITRDMDGSVDIDLPEPPKPTAPGQETEEERQFQALFKQVAGEDMEVTAEELKYVLNAVLQKKKDIKFKELSLISCKNIISLMDTSGNGKLEFSEFKVFWDKLKKWMSLFLQFDADKSGTMSSYELRSALKAAGFQLSSPLLQLIVLRYADPELQLGFDDFLNCLVRLENASRMFQALSTKNKEFIHLNINEFIVLTMNI", "length": 690, "header": "tr|F1RG55-1|A0A5G2QY66_PIG Computationally mapped isoform of Calpain 9 OS=Sus scrofa OX=9823 GN=CAPN9 PE=3 SV=2 CANONICAL=A0A5G2QY66-1" }, "locus": { "chromosome": "14", "start_pos": 59623317, "end_pos": 59582273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011148.3", "url": "https://www.ensembl.org/id/ENSSSCT00000011148.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010859.3", "url": "https://www.ensembl.org/id/ENSSSCP00000010859.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AXF0", "url": "https://www.uniprot.org/uniprotkb/A0A287AXF0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154688", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154688", "resource": "KEGG Pathway" }, { "id": "R-SSC-1474228", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1474228", "resource": "Reactome", "description": "Degradation of the extracellular matrix" } ], "orthologs": [ { "uniprot_canonical_ac": "O14815-1", "protein_name": "Calpain-9", "gene_name": "CAPN9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPYLYRAPGPQAHPVPKDARITHSSGQSFEQMRQECLQRGTLFEDADFPASNSSLFYSERPQIPFVWKRPGEIVKNPEFILGGATRTDICQGELGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIFHFQFWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCFIDTRSAAESEARTPFGLIKGHAYSVTGIDQVSFRGQRIELIRIRNPWGQVEWNGSWSDSSPEWRSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFDKVEICNLTPDALEEDAIHKWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKLKRFGANVLTIGYAIYECPDKDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQRFRALFEQVAGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFKVFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLDFDDFLNCLVRLENASRVFQALSTKNKEFIHLNINEFIHLTMNI", "length": 690 }, "evidence": [ { "id": "A0A5G2QY66", "url": "https://omabrowser.org/oma/group/A0A5G2QY66/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q11002-1", "protein_name": "Calpain-A", "gene_name": "CalpA", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDDLRGFLRQAGQEFLNAAGEAAMGAAKDVVGSVINEIFIKKEADTKRVLPSIKNMRVLGEKSSSLGPYSEVQDYETILNSCLASGSLFEDPLFPASNESLQFSRRPDRHIEWLRPHEIAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFEENYAGIFHFRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLKEAPGNLFTILQKAAERNSMMGCSIEPDPNVTEAETPQGLIRGHAYSITKVCLIDIVTPNRQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQNSGKRKWEMSMYEGEWTPGVTAGGCRNFLDTFWHNPQYIITLVDPDEEDEEGQCTVIVALMQKNRRSKRNMGMECLTIGFAIYSLNDRELENRPQGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETQNNMEENDDHVGYGGKADTITPGFPTPKPIDPQKEGLRRLFDSIAGKDMEVDWMELKRILDHSMRDDLPKPVVFNRFSNNMAFETQAAGPGDDGAGACGLLSLICGPFLKGTPFEEQLGMNDQSNKRLIGDNPADGGPVTANAIVDETHGFSKDVCRSMVAMLDADKSGKLGFEEFETLLSEIAKWKAIFKVYDVENTGRVSGFQLREALNSAGYHLNNRVLNVLGHRYGSRDGKIAFDDFIMCAVKIKTYIDIFKERDTEKNETATFTLEEWIERTIYS", "length": 828 }, "evidence": [ { "id": "A0A5G2QY66", "url": "https://omabrowser.org/oma/group/A0A5G2QY66/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9D805-1", "protein_name": "Calpain-9", "gene_name": "Capn9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPYLHRSLRPQPQPVPGDARTIHSSGQSFEQLRQGCLQSGTLFEDADFPASNVSLFYSERPQVPFVWKRPGEIVEKPEFILGGATRTDICQGELGDCWLLAAIASLTLNQKALTRVVPQDQGFGSGYAGIFHFQFWQHSEWLDVVIDDRLPTFKDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAENFQIREAPEDFFEILEKALKRGSLLGCSIDTLNASESEARTSLGLIKGHAYTVTGLDQVNFHGQRIKLIRVRNPWGQVEWNGPWSDSSPEWRSVDLEEQKRLGHTALDDGEFWMAFKDFKIHFDKVEICNLTPDALEDSALHRWEVTIHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTERDEGQEGCTFLAALMQKDRRRLKRFGANMLTIGYAIYQCPDKDGHLSRDFFRYHASLARSKTFINLREVSERFQLPPGDYILIPSTFEPHQEADFCLRIFSEKRAVTRDLDENIDIDLPELPKPTPQEEETEEEQQFRALFQRVAGEDMEVSAEELEYVLNAVLQKKTALKFKRLSLLSCRNIISLMDTSGNGKLEFEEFRVFWDKLKHWMDLFLQFDVDKSGTMSSYELRTALKAAGFQLGGHLLQLIVLRYADEDLQLDFDDYLNCLVRLENASRVFQSLSVKNKDFIHLNINEFISLTMNI", "length": 690 }, "evidence": [ { "id": "A0A5G2QY66", "url": "https://omabrowser.org/oma/group/A0A5G2QY66/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium-dependent cysteine-type endopeptidase activity", "id": "GO:0004198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004198", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY66", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY66", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY66", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY66", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QY66-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 664, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QY66-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QY66" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QY66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66" }, { "id": "PS50203", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50203" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calpain catalytic", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 311, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QY66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY66" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 565, "end_pos": 600, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 181, "end_pos": 183 }, { "start_pos": 309, "end_pos": 311 }, { "start_pos": 634, "end_pos": 636 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R660-1", "uniprot_ac": "A0A5G2R660", "uniprot_id": "A0A5G2R660_PIG", "mass": { "chemical_mass": 41702.0, "monoisotopic_mass": 41702.0 }, "refseq": { "ac": "XP_005666184", "name": "secretory carrier-associated membrane protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666184" }, "gene_names": [ { "name": "SCAMP2", "type": "recommended", "evidence": [ { "id": "A0A5G2R660", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660" } ] }, { "name": "SCAMP2", "type": "synonym", "evidence": [ { "id": "XP_005666184", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666184" } ] } ], "protein_names": [ { "name": "Secretory carrier-associated membrane protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R660", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660/entry#names_and_taxonomy" } ] }, { "name": "Secretory carrier membrane protein", "type": "synonym", "evidence": [ { "id": "A0A5G2R660", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660/entry#names_and_taxonomy" } ] }, { "name": "secretory carrier-associated membrane protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005666184", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666184" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R660", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SCAMP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660", "locus": { "chromosome": "7", "start_pos": 58699142, "end_pos": 58672664, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001892", "url": "https://www.ensembl.org/id/ENSSSCG00000001892" } ] } } ], "crossref": [ { "id": "A0A5G2R660", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R660", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001892", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001892", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100154517", "url": "https://www.ncbi.nlm.nih.gov/gene/100154517", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CLAWFTG", "url": "https://omabrowser.org/oma/group/CLAWFTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R660", "url": "https://www.orthodb.org/?gene=A0A5G2R660", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10687", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10687", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10687:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10687:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005666184", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666184", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AXL2", "url": "https://www.uniprot.org/uniprotkb/A0A287AXL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TRK7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TRK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TRL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TRL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QR23", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QR23-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R660", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R660-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAFDTNPFADPVDVNPFQDPSVTQLTNAPQGGLAEFNPFSETNAATTVPVTQLPGPSQPAVLQPSVEPTQPTPQLLLRQASRFLPTRFLAVSELSERQMLLGGDSILRDSYMRELPKAVASAAQASLLRQQEELDRKAAELERKERELQNTVANLHVRENNWPPLPIWCPIKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFLVDTSRGVDFGLSILWFVIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYIIQLVGIPSLGDSGWIAALSTLKEDLAVSIIMMVVAGFFTLCAVLSLFLLKRVHSLYRRTGASFQQAQEEFSQGIFSSRTFQSAASSAARGAFQGN", "length": 371, "header": "tr|A0A5G2R660-1|A0A5G2R660_PIG Isoform 1 of Secretory carrier-associated membrane protein OS=Sus scrofa OX=9823 GN=SCAMP2 PE=1 SV=1 CANONICAL=A0A5G2R660-1" }, "isoforms": [ { "isoform_ac": "A0A287AXL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660/entry#A0A287AXL2-1", "sequence": { "sequence": "MSAFDTNPFADPVDVNPFQDPSVTQLTNAPQGGLAEFNPFSETNAATTVPVTQLPGPSQPAAVASAAQASLLRQQEELDRKAAELERKERELQNTVANLHVRENNWPPLPIWCPIKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFLVDTSRGVDFGLSILWFVIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYIIQLVGIPSLGDSGWIAALSTLKEDLAVSIIMMVVAGFFTLCAVLSLFLLKRVHSLYRRTGASFQQAQEEFSQGIFSSRTFQSAASSAARGAFQGN", "length": 314, "header": "tr|A0A287AXL2-1|A0A5G2R660_PIG Computationally mapped isoform of Secretory carrier-associated membrane protein OS=Sus scrofa OX=9823 GN=SCAMP2 PE=1 SV=2 CANONICAL=A0A5G2R660-1" }, "locus": { "chromosome": "7", "start_pos": 58697758, "end_pos": 58672765, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050781.2", "url": "https://www.ensembl.org/id/ENSSSCT00000050781.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048685.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048685.2" } ] } }, { "isoform_ac": "A0A4X1TRK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660/entry#A0A4X1TRK7-1", "sequence": { "sequence": "MSAFDTNPFADPVDVNPFQDPSVTQLTNAPQGGLAEFNPFSEAVASAAQASLLRQQEELDRKAAELERKERELQNTVANLHVRENNWPPLPIWCPIKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFLVDTSRGVDFGLSILWFVIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYIIQLVGIPSLGDSGWIAALSTLKEDLAVSIIMMVVAGFFTLCAVLSLFLLKRVHSLYRRTGASFQQAQEEFSQGIFSSRTFQSAASSAARGAFQGN", "length": 295, "header": "tr|A0A4X1TRK7-1|A0A4X1TRK7_PIG Computationally mapped isoform of Secretory carrier-associated membrane protein OS=Sus scrofa OX=9823 GN=SCAMP2 PE=1 SV=1 CANONICAL=A0A5G2R660-1" }, "locus": { "chromosome": "7", "start_pos": 58697758, "end_pos": 58672765, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002118.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002118.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002068.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002068.3" } ] } }, { "isoform_ac": "A0A4X1TRL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660/entry#A0A4X1TRL2-1", "sequence": { "sequence": "MSAFDTNPFADPVDVNPFQAVASAAQASLLRQQEELDRKAAELERKERELQNTVANLHVRENNWPPLPIWCPIKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFLVDTSRGVDFGLSILWFVIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYIIQLVGIPSLGDSGWIAALSTLKEDLAVSIIMMVVAGFFTLCAVLSLFLLKRVHSLYRRTGASFQQAQEEFSQGIFSSRTFQSAASSAARGAFQGN", "length": 272, "header": "tr|A0A4X1TRL2-1|A0A4X1TRL2_PIG Computationally mapped isoform of Secretory carrier-associated membrane protein OS=Sus scrofa OX=9823 GN=SCAMP2 PE=1 SV=1 CANONICAL=A0A5G2R660-1" }, "locus": { "chromosome": "7", "start_pos": 58697758, "end_pos": 58672765, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048461.2", "url": "https://www.ensembl.org/id/ENSSSCT00000048461.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038628.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038628.1" } ] } }, { "isoform_ac": "A0A5G2QR23-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660/entry#A0A5G2QR23-1", "sequence": { "sequence": "MSAFDTNPFADPVDVNPFQDPSVTQLTNAPQGGLAEFNPFSETNAATTVPVTQLPGPSQPAVLQPSVEPTQPTPQAVASAAQASLLRQQEELDRKAAELERKERELQNTVANLHVRENNWPPLPIWCPIKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFLVDTSRGVDFGLSILWFVIFTPCAFLCWYRPIYKAFSPVHTEGRLGRVNHHDGGGWLLHPLCRALTLSPEAGSLPVPPDWGQLPAGPRGVFPGHLQQQDLPERRLICCPRSLPGELVLLPLLPLAQPFLSTCLLSCTFCGCLTQWLCPAQTWGGSRPCFFLLPQQPAVPST", "length": 345, "header": "tr|A0A5G2QR23-1|A0A5G2R660_PIG Computationally mapped isoform of Secretory carrier-associated membrane protein OS=Sus scrofa OX=9823 GN=SCAMP2 PE=1 SV=1 CANONICAL=A0A5G2R660-1" }, "locus": { "chromosome": "7", "start_pos": 58697925, "end_pos": 58672765, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089208.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089208.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067194.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067194.1" } ] } }, { "isoform_ac": "A0A5G2R660-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660/entry#A0A5G2R660-1", "sequence": { "sequence": "MSAFDTNPFADPVDVNPFQDPSVTQLTNAPQGGLAEFNPFSETNAATTVPVTQLPGPSQPAVLQPSVEPTQPTPQLLLRQASRFLPTRFLAVSELSERQMLLGGDSILRDSYMRELPKAVASAAQASLLRQQEELDRKAAELERKERELQNTVANLHVRENNWPPLPIWCPIKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFLVDTSRGVDFGLSILWFVIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYIIQLVGIPSLGDSGWIAALSTLKEDLAVSIIMMVVAGFFTLCAVLSLFLLKRVHSLYRRTGASFQQAQEEFSQGIFSSRTFQSAASSAARGAFQGN", "length": 371, "header": "tr|A0A5G2R660-1|A0A5G2R660_PIG Isoform 1 of Secretory carrier-associated membrane protein OS=Sus scrofa OX=9823 GN=SCAMP2 PE=1 SV=1 CANONICAL=A0A5G2R660-1" }, "locus": { "chromosome": "7", "start_pos": 58697758, "end_pos": 58672765, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067452.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067452.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072736.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072736.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AXL2", "url": "https://www.uniprot.org/uniprotkb/A0A287AXL2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1NV32-1", "protein_name": "Secretory carrier-associated membrane protein", "gene_name": "SCAMP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSFDTNPFADPVDVNPFQDPSVTQLTNASQSGLDEFNPFSESSQLTHAARTAPATQPSGPSQPAVLQTSVEPTPQAVAAAAQAGLLQQQAELERKAAELEKKERELQNNAASINPRQNNWPPLPRKCPIKPCFYQDFSADIPADYQRICKMLYYLWMLHSVTLLLNLLACLAWFMVHAEKGVDFGLSILWFVLFTPCAFLCWYRPIYKAFRSDSSFSFFVFFFVFFCQIAIYIIQAVGIPGWGDSGWIAALSELHRNTAVAIIMMVVAGFFTLCAVLSLFLLKQVHSLYRRTGASFQRAQEEFSQGILTNRSFQNAAAGAASSAARSAFRGN", "length": 333 }, "evidence": [ { "id": "A0A5G2R660", "url": "https://omabrowser.org/oma/group/A0A5G2R660/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O15127-1", "protein_name": "Secretory carrier-associated membrane protein 2", "gene_name": "SCAMP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAFDTNPFADPVDVNPFQDPSVTQLTNAPQGGLAEFNPFSETNAATTVPVTQLPGSSQPAVLQPSVEPTQPTPQAVVSAAQAGLLRQQEELDRKAAELERKERELQNTVANLHVRQNNWPPLPSWCPVKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFSGNSSKGVDFGLSILWFLIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYIIQLVGIPGLGDSGWIAALSTLDNHSLAISVIMMVVAGFFTLCAVLSVFLLQRVHSLYRRTGASFQQAQEEFSQGIFSSRTFHRAASSAAQGAFQGN", "length": 329 }, "evidence": [ { "id": "A0A5G2R660", "url": "https://omabrowser.org/oma/group/A0A5G2R660/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ERN0-1", "protein_name": "Secretory carrier-associated membrane protein 2", "gene_name": "Scamp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAFDTNPFADPVDVNPFQDPSVTQLTNAPQSGLAEFNPFSETNAATTVPATQAPGPSQPAVLQPSVEPAQPTPQAVAAAAQAGLLRQQEELDRKAAELERKERELQNTAANLHVRDNNWPPLPSWCPVKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFTSDAANGTAFGLSILWFLIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYFIQLIGLPNLGTSGWLAALSTMKNGPLAVTIIMMVVAGFFTLCAGLSLFLLQRVHAFYRRTGASFQQAQEEFSQGIFSSRTFRGAASSAARGAFQGN", "length": 329 }, "evidence": [ { "id": "A0A5G2R660", "url": "https://omabrowser.org/oma/group/A0A5G2R660/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SXA5-1", "protein_name": "Secretory carrier-associated membrane protein 5", "gene_name": "SCAMP5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGGRYDRNTFDEQDEVNPFANPGSVPAASNSRLSPLPPEPAGFGYGRTVDIPLDRPGSGAQDLKKKEKELQAKEADLRRREQDLKRKQDAAARAGIVIEAKNWPTFFPLIHHDIANEILVRLQRLQYIAFATYLGLVLALFWNIIAVTTAWIKGEGVTIWLLAVIYFISGVPGGYVLWYRPLYRAFRSDSAFNFGWFFLFYMLHILFCLFAAVAPPIVFKGKSLAGILPAIDVLSAQALVGIFYFIGFGLFCLESVVSIWVIQQVYMYFRGSGKADDMRRDAARGAMRAAI", "length": 291 }, "evidence": [ { "id": "A0A5G2R660", "url": "https://omabrowser.org/oma/group/A0A5G2R660/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R660", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R660", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R660", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R660", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R660", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R660" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R660-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 371, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R660-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R660" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 73 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2S7-1", "uniprot_ac": "A0A5G2R2S7", "uniprot_id": "A0A5G2R2S7_PIG", "mass": { "chemical_mass": 30913.0, "monoisotopic_mass": 30913.0 }, "refseq": {}, "gene_names": [ { "name": "RPRD1A", "type": "recommended", "evidence": [ { "id": "A0A5G2R2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7" } ] } ], "protein_names": [ { "name": "Regulation of nuclear pre-mRNA domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B672", "url": "https://www.uniprot.org/uniprotkb/A0A287B672#function" }, { "database": "UniProtKB", "id": "RU369021", "url": "https://www.uniprot.org/uniprotkb/RU369021#function" }, { "database": "UniProtKB", "id": "A0A287BF49", "url": "https://www.uniprot.org/uniprotkb/A0A287BF49#function" }, { "database": "UniProtKB", "id": "ARBA00035622", "url": "https://www.uniprot.org/uniprotkb/ARBA00035622#function" }, { "database": "UniProtKB", "id": "A0A5G2R2S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPRD1A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7", "locus": { "chromosome": "6", "start_pos": 119762812, "end_pos": 119834012, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027700", "url": "https://www.ensembl.org/id/ENSSSCG00000027700" } ] } } ], "crossref": [ { "id": "A0A5G2R2S7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2S7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000027700", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027700", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17011", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17011", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12460", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12460", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12460:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12460:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B672", "url": "https://www.uniprot.org/uniprotkb/A0A287B672", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B672-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B672-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BF49", "url": "https://www.uniprot.org/uniprotkb/A0A287BF49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BF49-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BF49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIQVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEVRNLFLI", "length": 270, "header": "tr|A0A5G2R2S7-1|A0A5G2R2S7_PIG Isoform 1 of Regulation of nuclear pre-mRNA domain-containing protein OS=Sus scrofa OX=9823 GN=RPRD1A PE=1 SV=1 CANONICAL=A0A5G2R2S7-1" }, "isoforms": [ { "isoform_ac": "A0A287B672-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7/entry#A0A287B672-1", "sequence": { "sequence": "GQGSNLQPHGSLSDSVLLRHDGNSFIAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIQVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHLPFAGDIYSED", "length": 288, "header": "tr|A0A287B672-1|A0A5G2R2S7_PIG Computationally mapped isoform of Regulation of nuclear pre-mRNA domain-containing protein OS=Sus scrofa OX=9823 GN=RPRD1A PE=1 SV=3 CANONICAL=A0A5G2R2S7-1" }, "locus": { "chromosome": "6", "start_pos": 119809897, "end_pos": 119766171, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038736.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038736.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051588.3", "url": "https://www.ensembl.org/id/ENSSSCP00000051588.3" } ] } }, { "isoform_ac": "A0A287BF49-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7/entry#A0A287BF49-1", "sequence": { "sequence": "MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIQVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEVLDMGVSSNDVIIISIFFLLKINNQT", "length": 289, "header": "tr|A0A287BF49-1|A0A5G2R2S7_PIG Computationally mapped isoform of Regulation of nuclear pre-mRNA domain-containing protein OS=Sus scrofa OX=9823 GN=RPRD1A PE=1 SV=3 CANONICAL=A0A5G2R2S7-1" }, "locus": { "chromosome": "6", "start_pos": 119833847, "end_pos": 119794503, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056812.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056812.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054751.3", "url": "https://www.ensembl.org/id/ENSSSCP00000054751.3" } ] } }, { "isoform_ac": "A0A5G2R2S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7/entry#A0A5G2R2S7-1", "sequence": { "sequence": "MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIQVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEVRNLFLI", "length": 270, "header": "tr|A0A5G2R2S7-1|A0A5G2R2S7_PIG Isoform 1 of Regulation of nuclear pre-mRNA domain-containing protein OS=Sus scrofa OX=9823 GN=RPRD1A PE=1 SV=1 CANONICAL=A0A5G2R2S7-1" }, "locus": { "chromosome": "6", "start_pos": 119833847, "end_pos": 119795948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087017.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087017.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064849.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064849.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B672", "url": "https://www.uniprot.org/uniprotkb/A0A287B672" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7" } ], "pmid": "" }, { "name": "RNA polymerase II CTD heptapeptide repeat phosphatase activity", "id": "GO:0008420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008420", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7" } ], "pmid": "" }, { "name": "RNA polymerase II C-terminal domain binding", "id": "GO:0099122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099122", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7" } ], "pmid": "" }, { "name": "RNA polymerase II promoter clearance", "id": "GO:0001111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001111", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "transcription preinitiation complex", "id": "GO:0097550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097550", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2S7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 270, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2S7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2S7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S7" }, { "id": "PS51391", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51391" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CID", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 133, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0I5-1", "uniprot_ac": "A0A5G2R0I5", "uniprot_id": "A0A5G2R0I5_PIG", "mass": { "chemical_mass": 173042.0, "monoisotopic_mass": 173042.0 }, "refseq": {}, "gene_names": [ { "name": "LTBP4", "type": "recommended", "evidence": [ { "id": "A0A5G2R0I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5" } ] } ], "protein_names": [ { "name": "Latent-transforming growth factor beta-binding protein 4", "type": "recommended", "evidence": [ { "id": "A0A5G2R0I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5#function" }, { "database": "UniProtKB", "id": "ARBA00057882", "url": "https://www.uniprot.org/uniprotkb/ARBA00057882#function" }, { "database": "UniProtKB", "id": "A0A8W4FF41", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF41#function" }, { "database": "UniProtKB", "id": "A0A287BGV1", "url": "https://www.uniprot.org/uniprotkb/A0A287BGV1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LTBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5", "locus": { "chromosome": "6", "start_pos": 48861507, "end_pos": 48831014, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000033760", "url": "https://www.ensembl.org/id/ENSSSCG00000033760" } ] } } ], "crossref": [ { "id": "ENSSSCG00000033760", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033760", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24034:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24034:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24039", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24039", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24039:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24039:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00683", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00683", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2129379", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2129379", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2173789", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2173789", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BGV1", "url": "https://www.uniprot.org/uniprotkb/A0A287BGV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BGV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BGV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FF41", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FF41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLPGPSGRRPLLLVLLLPLLAAAATAASAARPSQAVEVAVIPGRPAGVAACRCCPGRSPRRSRCFRASCRVRSCWPEKCVGPQRCLTLVPPELPSPSPSVRKRQVSLNWQPLTLQEARALLRRRRPRGPGARALLRRRPPQRAPAGQSRVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSTGARPPAPAMPGFTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCGGAGLAWGVHDCQSCSELLGNSDQAGAPDGPCPAGFERVNGSCEDVDECATGGRCQHGECANTHGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGPEPPRVSLSQARAPSSTSRPPAGFLPTHRPEPRPEPRPEPRPRPELPLPSIPAWTGPEIPESGPSAGECQRNPQICGPGRCIPRHGGYTCACDSGFRLSPQGTHCLDVDECRRVPTPCAPGRCENTPGSFRCVCGPGFRAGLRATECLDVDECHRVPPPCDRGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECIQSPGLCGRGVCENLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCAYGRCENTEGGFQCVCPTGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPAGHHLHHGRCTDVDECSSGASCGSHGHCTNTEGSFHCSCEPGYRVPSGRPGPCTDVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGSSCLDVDECSEEDLCQSGICTNTDGSFECVCPPGHRAGPDLASCLDIDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPAICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGSFTGSQPHAPASHSLPARPPPPAPPRRPSPPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPSTETAEYQSLCPHGRGYLAPSGDPSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTIGSYHCTCEPPLVLDGSRRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYGPPRPGGFGLPYEYGLDLGPPYQGLPYGPELYPPPVLPYDPYPPPPGPFARREAPYGTPPFDMPDFEDDGGPYGESEAPGPPGPGTRWRYRSRDTRGSFPEPEESPEGGSYAGSRAGAYEGLEAEECGILDGCAHGRCVRVPEGFTCDCFDGYRLDMTRMACVDINECDEAEAASPLCINARCVNTDGSFRCICRPGFAPSHEPHHCTPARPRA", "length": 1622, "header": "tr|A0A5G2R0I5-1|A0A5G2R0I5_PIG Isoform 1 of Latent-transforming growth factor beta-binding protein 4 OS=Sus scrofa OX=9823 GN=LTBP4 PE=1 SV=1 CANONICAL=A0A5G2R0I5-1" }, "isoforms": [ { "isoform_ac": "A0A287BGV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5/entry#A0A287BGV1-1", "sequence": { "sequence": "MAGGARLLWVSLLVLLALLRPQPGLGRPQERLRVRFTPAVCGLRCVHGPTGPRCTPTCAPRNTTSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSTGARPPAPAMPGFTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCGGAGLAWGVHDCQSCSELLGNSDQAGAPDGPCPAGFERVNGSCEAQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGPEPPRVSLSQARAPSSTSRPPAGFLPTHRPEPRPEPRPELRPEPRPEPRPRPELPLPSIPAWTGPEIPESGPSAGECQRNPQICGPGRCIPRHGGYTCACDSGFRLSPQGTHCLDVDECRRVPTPCAPGRCENTPGSFRCVCGPGFRAGLRATECLDVDECHRVPPPCDRGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECIQSPGLCGRGVCENLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCAYGRCENTEGGFQCVCPTGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPAGHHLHHGRCTDVDECSSGASCGSHGHCTNTEGSFHCSCEPGYRVPSGRPGPCTDVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGSSCLDVDECSEEDLCQSGICTNTDGSFECVCPPGHRAGPDLASCLDIDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPAICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGSFTGSQPHAPASHSLPARPPPPAPPRRPSPPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPSTETAEYQSLCPHGRGYLAPSGDPSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTIGSYHCTCEPPLVLDGSRRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYGPPRPGGFGLPYEYGLDLGPPYQGLPYGPELYPPPVLPYDPYPPPPGPFARREAPYGTPPFDMPDFEDDGGPYGESEAPGPPGPGTRWRYRSRDTRGSFPEPEESPEGGSYAGSRAGAYEGLEAEECGILDGCAHGRCVRVPEGFTCDCFDGYRLDMTRMACVDINECDEAEAASPLCINARCVNTDGSFRCICRPGFAPSHEPHHCTPARPRA", "length": 1523, "header": "tr|A0A287BGV1-1|A0A5G2R0I5_PIG Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 4 OS=Sus scrofa OX=9823 GN=LTBP4 PE=1 SV=2 CANONICAL=A0A5G2R0I5-1" }, "locus": { "chromosome": "6", "start_pos": 48861240, "end_pos": 48835191, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051354.2", "url": "https://www.ensembl.org/id/ENSSSCT00000051354.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055818.2", "url": "https://www.ensembl.org/id/ENSSSCP00000055818.2" } ] } }, { "isoform_ac": "A0A5G2R0I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5/entry#A0A5G2R0I5-1", "sequence": { "sequence": "MRLPGPSGRRPLLLVLLLPLLAAAATAASAARPSQAVEVAVIPGRPAGVAACRCCPGRSPRRSRCFRASCRVRSCWPEKCVGPQRCLTLVPPELPSPSPSVRKRQVSLNWQPLTLQEARALLRRRRPRGPGARALLRRRPPQRAPAGQSRVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSTGARPPAPAMPGFTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCGGAGLAWGVHDCQSCSELLGNSDQAGAPDGPCPAGFERVNGSCEDVDECATGGRCQHGECANTHGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGPEPPRVSLSQARAPSSTSRPPAGFLPTHRPEPRPEPRPEPRPRPELPLPSIPAWTGPEIPESGPSAGECQRNPQICGPGRCIPRHGGYTCACDSGFRLSPQGTHCLDVDECRRVPTPCAPGRCENTPGSFRCVCGPGFRAGLRATECLDVDECHRVPPPCDRGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECIQSPGLCGRGVCENLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCAYGRCENTEGGFQCVCPTGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPAGHHLHHGRCTDVDECSSGASCGSHGHCTNTEGSFHCSCEPGYRVPSGRPGPCTDVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGSSCLDVDECSEEDLCQSGICTNTDGSFECVCPPGHRAGPDLASCLDIDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPAICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGSFTGSQPHAPASHSLPARPPPPAPPRRPSPPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPSTETAEYQSLCPHGRGYLAPSGDPSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTIGSYHCTCEPPLVLDGSRRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYGPPRPGGFGLPYEYGLDLGPPYQGLPYGPELYPPPVLPYDPYPPPPGPFARREAPYGTPPFDMPDFEDDGGPYGESEAPGPPGPGTRWRYRSRDTRGSFPEPEESPEGGSYAGSRAGAYEGLEAEECGILDGCAHGRCVRVPEGFTCDCFDGYRLDMTRMACVDINECDEAEAASPLCINARCVNTDGSFRCICRPGFAPSHEPHHCTPARPRA", "length": 1622, "header": "tr|A0A5G2R0I5-1|A0A5G2R0I5_PIG Isoform 1 of Latent-transforming growth factor beta-binding protein 4 OS=Sus scrofa OX=9823 GN=LTBP4 PE=1 SV=1 CANONICAL=A0A5G2R0I5-1" }, "locus": { "chromosome": "6", "start_pos": 48861240, "end_pos": 48831081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067071.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067071.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069900.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069900.1" } ] } }, { "isoform_ac": "A0A8W4FF41-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5/entry#A0A8W4FF41-1", "sequence": { "sequence": "MRLPGPSGRRPLLLVLLLPLLAAAATAASAARPSQAVEVAVIPGRPAGVAACRCCPGRSPRRSRCFRASCRVRSCWPEKCVGPQRCLTLVPPELPSPSPSVRKRQVSLNWQPLTLQEARALLRRRRPRGPGARALLRRRPPQRAPAGQSRVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSTGARPPAPAMPGFTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCGGAGLAWGVHDCQSCSELLGNSDQAGAPDGPCPAGFERVNGSCEDVDECATGGRCQHGECANTHGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGPEPPRVSLSQARAPSSTSRPPAGFLPTHRPEPRPEPRPELRPEPRPEPRPRPELPLPSIPAWTGPEIPESGPSAGECQRNPQICGPGRCIPRHGGYTCACDSGFRLSPQGTHCLDVDECRRVPTPCAPGRCENTPGSFRCVCGPGFRAGLRATECLDVDECHRVPPPCDRGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECIQSPGLCGRGVCENLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCAYGRCENTEGGFQCVCPTGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPAGHHLHHGRCTDVDECSSGASCGSHGHCTNTEGSFHCSCEPGYRVPSGRPGPCTDVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGSSCLDVDECSEEDLCQSGICTNTDGSFECVCPPGHRAGPDLASCLDIDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPAICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGSFTGSQPHAPASHSLPARPPPPAPPRRPSPPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPSTETAEYQSLCPHGRGYLAPSGDPSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTIGSYHCTCEPPLVLDGSRRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYGPPRPGGFGLPYEYGLDLGPPYQGLPYGPELYPPPVLPYDPYPPPPGPFARREAPYGTPPFDMPDFEDDGGPYGESEAPGPPGPGTRWRYRSRDTRGSFPEPEESPEGGSYAGSRAGAYEGLEAEECGILDGCAHGRCVRVPEGFTCDCFDGYRLDMTRMACVDINECDEAEAASPLCINARCVNTDGSFRCICRPGFAPSHEPHHCTPARPRA", "length": 1630, "header": "tr|A0A8W4FF41-1|A0A5G2R0I5_PIG Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 4 OS=Sus scrofa OX=9823 GN=LTBP4 PE=1 SV=1 CANONICAL=A0A5G2R0I5-1" }, "locus": { "chromosome": "6", "start_pos": 48861240, "end_pos": 48831081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091747.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091747.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077482.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077482.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1040, "start_aa": "Thr", "end_pos": 1040, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1040", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FF41", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF41" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2129379", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2129379", "resource": "Reactome", "description": "Molecules associated with elastic fibres" }, { "id": "R-SSC-2173789", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2173789", "resource": "Reactome", "description": "TGF-beta receptor signaling activates SMADs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5" } ], "pmid": "" }, { "name": "transforming growth factor beta binding", "id": "GO:0050431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050431", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5" } ], "pmid": "" }, { "name": "microfibril", "id": "GO:0001527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001527", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1053, "end_pos": 1055, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1198, "end_pos": 1200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1337, "end_pos": 1339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 181, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R0I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0I5" }, { "id": "PS51364", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51364" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TB", "eco_id": "ECO_0000259", "start_pos": 287, "end_pos": 327, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1040 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1053, "end_pos": 1055 }, { "start_pos": 1198, "end_pos": 1200 }, { "start_pos": 1337, "end_pos": 1339 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 424, "end_pos": 426 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWN8-1", "uniprot_ac": "A0A5G2QWN8", "uniprot_id": "A0A5G2QWN8_PIG", "mass": { "chemical_mass": 35631.0, "monoisotopic_mass": 35631.0 }, "refseq": {}, "gene_names": [ { "name": "HNRNPAB", "type": "recommended", "evidence": [ { "id": "A0A5G2QWN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8" } ] } ], "protein_names": [ { "name": "Heterogeneous nuclear ribonucleoprotein A/B", "type": "recommended", "evidence": [ { "id": "A0A5G2QWN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HNRNPAB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QWN8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014031", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014031", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12584", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12584", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12757", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12757", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100127170", "url": "https://www.ncbi.nlm.nih.gov/gene/100127170", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NQGYNYW", "url": "https://omabrowser.org/oma/group/NQGYNYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287BMB6", "url": "https://www.orthodb.org/?gene=A0A287BMB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48033", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48033", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48033:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48033:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08143", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08143", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287BMB6", "url": "https://www.uniprot.org/uniprotkb/A0A287BMB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BMB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BMB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWN8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S420", "url": "https://www.uniprot.org/uniprotkb/F1S420", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S420-1", "url": "https://www.uniprot.org/uniprotkb/F1S420-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEAGEEQPMETTGATENGHEAAPEGESPAGTGTGAAAGSGGGTAAPPAGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKSNKRRGFVFITFKEEEPVKKVLEKKFHTISGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGQSQSWNQGYGSYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY", "length": 327, "header": "tr|A0A5G2QWN8-1|A0A5G2QWN8_PIG Isoform 1 of Heterogeneous nuclear ribonucleoprotein A/B OS=Sus scrofa OX=9823 GN=HNRNPAB PE=1 SV=1 CANONICAL=A0A5G2QWN8-1" }, "isoforms": [ { "isoform_ac": "A0A287BMB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8/entry#A0A287BMB6-1", "sequence": { "sequence": "MSEAGEEQPMETTGATENGHEAAPEGESPAGTGTGTGTGTGTSTSSGAAAGSGGGTAAPPAGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKSNKRRGFVFITFKEEEPVKKVLEKKFHTISGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGSGGGQSQSWNQGYGSYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY", "length": 345, "header": "tr|A0A287BMB6-1|A0A5G2QWN8_PIG Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein A/B OS=Sus scrofa OX=9823 GN=HNRNPAB PE=1 SV=1 CANONICAL=A0A5G2QWN8-1" }, "locus": { "chromosome": "2", "start_pos": 80193800, "end_pos": 80187544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046549.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046549.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057558.1", "url": "https://www.ensembl.org/id/ENSSSCP00000057558.1" } ] } }, { "isoform_ac": "A0A5G2QWN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8/entry#A0A5G2QWN8-1", "sequence": { "sequence": "MSEAGEEQPMETTGATENGHEAAPEGESPAGTGTGAAAGSGGGTAAPPAGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKSNKRRGFVFITFKEEEPVKKVLEKKFHTISGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGQSQSWNQGYGSYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY", "length": 327, "header": "tr|A0A5G2QWN8-1|A0A5G2QWN8_PIG Isoform 1 of Heterogeneous nuclear ribonucleoprotein A/B OS=Sus scrofa OX=9823 GN=HNRNPAB PE=1 SV=1 CANONICAL=A0A5G2QWN8-1" }, "locus": { "chromosome": "2", "start_pos": 80193800, "end_pos": 80187544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088957.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088957.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069281.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069281.1" } ] } }, { "isoform_ac": "F1S420-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8/entry#F1S420-1", "sequence": { "sequence": "MSEAGEEQPMETTGATENGHEAAPEGESPAGTGTGTGTGTGTSTSSGAAAGSGGGTAAPPAGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKSNKRRGFVFITFKEEEPVKKVLEKKFHTISGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGSGGGQGSTNYGKSQRRGGHQNNYKPY", "length": 298, "header": "tr|F1S420-1|A0A5G2QWN8_PIG Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein A/B OS=Sus scrofa OX=9823 GN=HNRNPAB PE=1 SV=3 CANONICAL=A0A5G2QWN8-1" }, "locus": { "chromosome": "2", "start_pos": 80193800, "end_pos": 80187544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015327.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015327.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014919.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014919.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S420", "url": "https://www.uniprot.org/uniprotkb/F1S420" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LZD9-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A/B", "gene_name": "HNRNPAB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSEAGEEQPMETTGATENGHEAAPEGESPAGTGTGVAAGAGGGSAAPQAGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDATSVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKSNKRRGFVFITFKEEEPVKKVLEKKFHTISGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGSGGQSQSWNQGYGSYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY", "length": 332 }, "evidence": [ { "id": "A0A5G2QWN8", "url": "https://omabrowser.org/oma/group/A0A5G2QWN8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0YRG0-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A/B", "gene_name": "HNRNPAB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSEAEQQLAAAAGATQNGHEAAESSGEQQQADTGGAPAASAGAATAAAATAGTAAAAGAGPAAGTAGVAASQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVTDCTIKMDPNTGRSRGFGFILFKEPGSVEKVLEQKEHRLDGRLIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKTNKRRGFVFITFKEEDPVKKVLEKKFHNVSGSKCEIKVAQPKEVYQQQQFSSGGGRGSYGGRGRGGRGGAQSQNWNQGYGNYWNQGYGNQGYGYQQGYGGYGGYDYSGYGYYGYGPGYDYSQGSANYGKTPRRGGHQNNYKPY", "length": 353 }, "evidence": [ { "id": "A0A5G2QWN8", "url": "https://omabrowser.org/oma/group/A0A5G2QWN8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q99729-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A/B", "gene_name": "HNRNPAB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEAGEEQPMETTGATENGHEAVPEASRGRGWTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPESPTEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY", "length": 332 }, "evidence": [ { "id": "A0A5G2QWN8", "url": "https://omabrowser.org/oma/group/A0A5G2QWN8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of macromolecule biosynthetic process", "id": "GO:0010557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010557", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWN8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 327, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWN8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWN8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN8" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 155, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R278-1", "uniprot_ac": "A0A5G2R278", "uniprot_id": "A0A5G2R278_PIG", "mass": { "chemical_mass": 52293.0, "monoisotopic_mass": 52293.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100155138", "type": "recommended", "evidence": [ { "id": "A0A5G2R278", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278" } ] } ], "protein_names": [ { "name": "Tubulin alpha chain", "type": "recommended", "evidence": [ { "id": "A0A5G2R278", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.", "evidence": [ { "database": "UniProtKB", "id": "F1RK98", "url": "https://www.uniprot.org/uniprotkb/F1RK98#function" }, { "database": "UniProtKB", "id": "RU000352", "url": "https://www.uniprot.org/uniprotkb/RU000352#function" }, { "database": "UniProtKB", "id": "A0A5G2R278", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278#function" } ] }, { "annotation": "Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.", "evidence": [ { "database": "UniProtKB", "id": "F1RK98", "url": "https://www.uniprot.org/uniprotkb/F1RK98#function" }, { "database": "UniProtKB", "id": "ARBA00093431", "url": "https://www.uniprot.org/uniprotkb/ARBA00093431#function" }, { "database": "UniProtKB", "id": "A0A5G2R278", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R278", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100155138", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278", "locus": {} } ], "crossref": [ { "id": "A0A5G2R278", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R278", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010099", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010099", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSSSCG00000010103", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010103", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02186", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02186", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017975", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017975", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11588", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11588", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-190840", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-190840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2132295", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3371497", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371497", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5610787", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5610787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5620920", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620920", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5626467", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5626467", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68877", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8852276", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8852276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8955332", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8955332", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9646399", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9646399", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9668328", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9668328", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983189", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983189", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R278", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R278-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RK98", "url": "https://www.uniprot.org/uniprotkb/F1RK98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RK98-1", "url": "https://www.uniprot.org/uniprotkb/F1RK98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QPEPLQSLTTAMQTGASHICSGPQRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEAEEGEEY", "length": 473, "header": "tr|A0A5G2R278-1|A0A5G2R278_PIG Isoform 1 of Tubulin alpha chain OS=Sus scrofa OX=9823 GN=LOC100155138 PE=3 SV=2 CANONICAL=A0A5G2R278-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R278-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278/entry#A0A5G2R278-1", "sequence": { "sequence": "QPEPLQSLTTAMQTGASHICSGPQRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEAEEGEEY", "length": 473, "header": "tr|A0A5G2R278-1|A0A5G2R278_PIG Isoform 1 of Tubulin alpha chain OS=Sus scrofa OX=9823 GN=LOC100155138 PE=3 SV=2 CANONICAL=A0A5G2R278-1" }, "locus": { "chromosome": "14", "start_pos": 50657257, "end_pos": 50652053, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083740.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083740.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070450.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070450.2" } ] } }, { "isoform_ac": "F1RK98-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278/entry#F1RK98-1", "sequence": { "sequence": "LFWASHICSGPQRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEAEEGEEY", "length": 461, "header": "tr|F1RK98-1|A0A5G2R278_PIG Computationally mapped isoform of Tubulin alpha chain OS=Sus scrofa OX=9823 GN=LOC100155138 PE=3 SV=5 CANONICAL=A0A5G2R278-1" }, "locus": { "chromosome": "14", "start_pos": 50657257, "end_pos": 50652693, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011064.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011064.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010776.5", "url": "https://www.ensembl.org/id/ENSSSCP00000010776.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RK98", "url": "https://www.uniprot.org/uniprotkb/F1RK98" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-190840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-190840", "resource": "Reactome", "description": "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane" }, { "id": "R-SSC-2132295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "resource": "Reactome", "description": "MHC class II antigen presentation" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-SSC-3371497", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371497", "resource": "Reactome", "description": "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" }, { "id": "R-SSC-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-SSC-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" }, { "id": "R-SSC-5620920", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620920", "resource": "Reactome", "description": "Cargo trafficking to the periciliary membrane" }, { "id": "R-SSC-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620924", "resource": "Reactome", "description": "Intraflagellar transport" }, { "id": "R-SSC-5626467", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5626467", "resource": "Reactome", "description": "RHO GTPases activate IQGAPs" }, { "id": "R-SSC-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-SSC-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-SSC-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-SSC-68877", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "resource": "Reactome", "description": "Mitotic Prometaphase" }, { "id": "R-SSC-8852276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8852276", "resource": "Reactome", "description": "The role of GTSE1 in G2/M progression after G2 checkpoint" }, { "id": "R-SSC-8955332", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8955332", "resource": "Reactome", "description": "Carboxyterminal post-translational modifications of tubulin" }, { "id": "R-SSC-9646399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9646399", "resource": "Reactome", "description": "Aggrephagy" }, { "id": "R-SSC-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" }, { "id": "R-SSC-9668328", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9668328", "resource": "Reactome", "description": "Sealing of the nuclear envelope (NE) by ESCRT-III" }, { "id": "R-SSC-983189", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983189", "resource": "Reactome", "description": "Kinesins" }, { "id": "R-SSC-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R278", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R278", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R278", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R278", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R278", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "microtubule-based process", "id": "GO:0007017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R278", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R278", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R278", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R278-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 473, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R278-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R278" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R278", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278" }, { "id": "SM00865", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubulin/FtsZ 2-layer sandwich", "eco_id": "ECO_0000259", "start_pos": 271, "end_pos": 416, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R278", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R278" }, { "id": "SM00864", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00864" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubulin/FtsZ GTPase", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 269, "start_aa": "Phe", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 403, "end_pos": 405 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZR2-1", "uniprot_ac": "A0A5G2QZR2", "uniprot_id": "A0A5G2QZR2_PIG", "mass": { "chemical_mass": 16218.0, "monoisotopic_mass": 16218.0 }, "refseq": { "ac": "XP_003131117", "name": "gamma-glutamylaminecyclotransferase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131117" }, "gene_names": [ { "name": "GGACT", "type": "recommended", "evidence": [ { "id": "A0A5G2QZR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2" } ] }, { "name": "GGACT", "type": "synonym", "evidence": [ { "id": "XP_003131117", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131117" } ] } ], "protein_names": [ { "name": "Gamma-glutamylaminecyclotransferase", "type": "recommended", "evidence": [ { "id": "A0A5G2QZR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2/entry#names_and_taxonomy" } ] }, { "name": "4.3.2.8", "type": "synonym", "evidence": [ { "id": "A0A5G2QZR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2/entry#names_and_taxonomy" } ] }, { "name": "gamma-glutamylaminecyclotransferase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003131117", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131117" } ] } ], "function": [ { "annotation": "Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.", "evidence": [ { "database": "UniProtKB", "id": "F1RP13", "url": "https://www.uniprot.org/uniprotkb/F1RP13#function" }, { "database": "UniProtKB", "id": "RU367036", "url": "https://www.uniprot.org/uniprotkb/RU367036#function" }, { "database": "UniProtKB", "id": "A0A5G2QZR2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2#function" } ] }, { "annotation": "Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.", "evidence": [ { "database": "UniProtKB", "id": "F1RP13", "url": "https://www.uniprot.org/uniprotkb/F1RP13#function" }, { "database": "UniProtKB", "id": "ARBA00059877", "url": "https://www.uniprot.org/uniprotkb/ARBA00059877#function" }, { "database": "UniProtKB", "id": "A0A5G2QZR2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZR2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GGACT", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000009523", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009523", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524456", "url": "https://www.ncbi.nlm.nih.gov/gene/100524456", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524456", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524456", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FENIPTM", "url": "https://omabrowser.org/oma/group/FENIPTM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QZR2", "url": "https://www.orthodb.org/?gene=A0A5G2QZR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12510", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12510", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12510:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12510:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003131117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131117", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16961", "url": "https://www.rhea-db.org/rhea/16961", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QZR2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP13", "url": "https://www.uniprot.org/uniprotkb/F1RP13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP13-1", "url": "https://www.uniprot.org/uniprotkb/F1RP13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHVFVYGTLKTGQPNHRVLLDGAHGRATLRGRARTLEPYPLVIAGEHNIPWLLQLPGHGRCVAGEVYAVDEQMLRFLDEFEGCPDMYQRTRLTVAVEGPAGGTVQCFAYSTATYPPEWLQLPHLDDYDSQGEHGLRYNPRENR", "length": 144, "header": "tr|A0A5G2QZR2-1|A0A5G2QZR2_PIG Isoform 1 of Gamma-glutamylaminecyclotransferase OS=Sus scrofa OX=9823 GN=GGACT PE=1 SV=1 CANONICAL=A0A5G2QZR2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2/entry#A0A5G2QZR2-1", "sequence": { "sequence": "MAHVFVYGTLKTGQPNHRVLLDGAHGRATLRGRARTLEPYPLVIAGEHNIPWLLQLPGHGRCVAGEVYAVDEQMLRFLDEFEGCPDMYQRTRLTVAVEGPAGGTVQCFAYSTATYPPEWLQLPHLDDYDSQGEHGLRYNPRENR", "length": 144, "header": "tr|A0A5G2QZR2-1|A0A5G2QZR2_PIG Isoform 1 of Gamma-glutamylaminecyclotransferase OS=Sus scrofa OX=9823 GN=GGACT PE=1 SV=1 CANONICAL=A0A5G2QZR2-1" }, "locus": { "chromosome": "11", "start_pos": 69288759, "end_pos": 69288328, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074171.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074171.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072130.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072130.1" } ] } }, { "isoform_ac": "F1RP13-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2/entry#F1RP13-1", "sequence": { "sequence": "MPATGLGDVLLPLCPLALRHSLCSLTFVFVSPAAGLRTGCLVPGLLAPLRGGSPSPGVLFPRILRPNAFQTHTYHGVGFWADGVLKKQASSGGRMAHVFVYGTLKTGQPNHRVLLDGAHGRATLRGRARTLEPYPLVIAGEHNIPWLLQLPGHGRCVAGEVYAVDEQMLRFLDEFEGCPDMYQRTRLTVAVEGPAGGTVQCFAYSTATYPPEWLQLPHLDDYDSQGEHGLRYNPRENR", "length": 238, "header": "tr|F1RP13-1|A0A5G2QZR2_PIG Computationally mapped isoform of Gamma-glutamylaminecyclotransferase OS=Sus scrofa OX=9823 GN=GGACT PE=1 SV=4 CANONICAL=A0A5G2QZR2-1" }, "locus": { "chromosome": "11", "start_pos": 69344665, "end_pos": 69288328, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010441.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010441.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010170.4", "url": "https://www.ensembl.org/id/ENSSSCP00000010170.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RP13", "url": "https://www.uniprot.org/uniprotkb/F1RP13" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524456", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524456", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q2U3N8-1", "protein_name": "Gamma-glutamylaminecyclotransferase", "gene_name": "GGACT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARVFVYGTLKKGQPNYKHMINTAKGIAKYQGRGRTVEKYPLVIAGKYNIPYMLNIPGTGHHIAGEIYTVDDQMLRFLDEFEGCPDMYQRTTMRIEVVEWEGKSGTAEVRPASSGVMECFVYNTSTYQPEWVQLPYHDNYDSSGTHGLSYVLRENRD", "length": 157 }, "evidence": [ { "id": "A0A5G2QZR2", "url": "https://omabrowser.org/oma/group/A0A5G2QZR2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HGS3-1", "protein_name": "Gamma-glutamylaminecyclotransferase", "gene_name": "Ggact", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAHIFVYGTLKRGQPNHKVMLDQSHGSAVFQGRGCTVESFPLVIAGEHNIPWLLHVPGKGHRVEGEIYKVDEQMLRFLDDFEGCPTMYQRTALQVQVLEWEGAGGPVDSLQCFVYSTATYVPEWLHLPYHKSYDSEGPHGLPYNPRENR", "length": 149 }, "evidence": [ { "id": "A0A5G2QZR2", "url": "https://omabrowser.org/oma/group/A0A5G2QZR2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4KM86-1", "protein_name": "Gamma-glutamylaminecyclotransferase", "gene_name": "Ggact", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHIFVYGTLKRGQPNHKVMLDQSHGLATFRGRGCTVESFPLVIAGEHNIPWLLHLPGKGHCVAGEIYEVDEQMLRFLDDFEGCPSMYQRTALQVRVLEWEGAGGPGDSVQCFVYSTATYAPEWLFLPYHKNYDSEGPHGLRYNPRENR", "length": 149 }, "evidence": [ { "id": "A0A5G2QZR2", "url": "https://omabrowser.org/oma/group/A0A5G2QZR2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66I06-1", "protein_name": "Gamma-glutamylaminecyclotransferase B", "gene_name": "ggact.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPLVFVYGTLKKGQPNYFRLIDSSNGQAEFITCARTVEPYPLVITGECNIPFLLNVPGSGQRVYGEIYSVDQKMLEFLDWFEECPDWYQRTLIQLEILKGNGETEVEEAFVYTKTKYEPDWLNKPTYDSYDSNGDHGLKYAYEEDMTRSTLDQKSADFSQNSEQEIKKNNSLQILTSTGDDHDVNFRGPLQ", "length": 191 }, "evidence": [ { "id": "A0A5G2QZR2", "url": "https://omabrowser.org/oma/group/A0A5G2QZR2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q923B0-1", "protein_name": "Gamma-glutamylaminecyclotransferase", "gene_name": "Ggact", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAHIFVYGTLKRGQPNHKVMLDHSHGLAAFRGRGCTVESFPLVIAGEHNIPWLLYLPGKGHCVTGEIYEVDEQMLRFLDDFEDCPSMYQRTALQVQVLEWEGDGDPGDSVQCFVYTTATYAPEWLFLPYHESYDSEGPHGLRYNPRENR", "length": 149 }, "evidence": [ { "id": "A0A5G2QZR2", "url": "https://omabrowser.org/oma/group/A0A5G2QZR2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BVM4-1", "protein_name": "Gamma-glutamylaminecyclotransferase", "gene_name": "GGACT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALVFVYGTLKRGQPNHRVLRDGAHGSAAFRARGRTLEPYPLVIAGEHNIPWLLHLPGSGRLVEGEVYAVDERMLRFLDDFESCPALYQRTVLRVQLLEDRAPGAEEPPAPTAVQCFVYSRATFPPEWAQLPHHDSYDSEGPHGLRYNPRENR", "length": 153 }, "evidence": [ { "id": "A0A5G2QZR2", "url": "https://omabrowser.org/oma/group/A0A5G2QZR2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W0Y1-1", "protein_name": "Troponin C-akin-1 protein", "gene_name": "Tina-1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGQAKKVSSALSKLFVYGALKYGQPSNSILASSGNGFAKFWCKATTTQKLPLVIATRYNIPFLLNKPGVGYYVTGEIYEVDDRMLNSLDNLEDCEEIYTREMHDMNIGVGEGTVPCWVYLLQKYPENLLSLRYLSSYENSTTHPYIMRHRRTHKHPAQDDLTYEAQN", "length": 167 }, "evidence": [ { "id": "A0A5G2QZR2", "url": "https://omabrowser.org/oma/group/A0A5G2QZR2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "modified amino acid catabolic process", "id": "GO:0042219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042219", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZR2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "gamma-glutamylaminecyclotransferase activity", "id": "GO:0061929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061929", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZR2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZR2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16961", "name": "", "equation": "epsilon-(gamma-L-glutamyl)-L-lysine = 5-oxo-L-proline + L-lysine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16961", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16961" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZR2" }, { "id": "PF06094", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06094" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gamma-glutamylcyclotransferase AIG2-like", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 128, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2M6-1", "uniprot_ac": "A0A5G2R2M6", "uniprot_id": "A0A5G2R2M6_PIG", "mass": { "chemical_mass": 90187.0, "monoisotopic_mass": 90187.0 }, "refseq": {}, "gene_names": [ { "name": "CUL5", "type": "recommended", "evidence": [ { "id": "A0A5G2R2M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ] } ], "protein_names": [ { "name": "Cullin-5", "type": "recommended", "evidence": [ { "id": "A0A5G2R2M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CUL5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6", "locus": { "chromosome": "9", "start_pos": 36507667, "end_pos": 36419881, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000029198", "url": "https://www.ensembl.org/id/ENSSSCG00000029198" } ] } } ], "crossref": [ { "id": "A0A5G2R2M6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2M6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000029198", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000029198", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00888", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00888", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8863795", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8863795", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZMU8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZMU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZMU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZMU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQC8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LFR2", "url": "https://www.uniprot.org/uniprotkb/I3LFR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LFR2-1", "url": "https://www.uniprot.org/uniprotkb/I3LFR2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRCSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLMGKQGSNKKSNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA", "length": 772, "header": "tr|A0A5G2R2M6-1|A0A5G2R2M6_PIG Isoform 1 of Cullin-5 OS=Sus scrofa OX=9823 GN=CUL5 PE=1 SV=2 CANONICAL=A0A5G2R2M6-1" }, "isoforms": [ { "isoform_ac": "A0A286ZMU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6/entry#A0A286ZMU8-1", "sequence": { "sequence": "MATSNLLKNKGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLMGKQGSNKKSNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQVCNVKKNV", "length": 724, "header": "tr|A0A286ZMU8-1|A0A5G2R2M6_PIG Computationally mapped isoform of Cullin-5 OS=Sus scrofa OX=9823 GN=CUL5 PE=1 SV=3 CANONICAL=A0A5G2R2M6-1" }, "locus": { "chromosome": "9", "start_pos": 36499734, "end_pos": 36420299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058652.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058652.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032780.3", "url": "https://www.ensembl.org/id/ENSSSCP00000032780.3" } ] } }, { "isoform_ac": "A0A5G2R2M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6/entry#A0A5G2R2M6-1", "sequence": { "sequence": "MRCSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLMGKQGSNKKSNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA", "length": 772, "header": "tr|A0A5G2R2M6-1|A0A5G2R2M6_PIG Isoform 1 of Cullin-5 OS=Sus scrofa OX=9823 GN=CUL5 PE=1 SV=2 CANONICAL=A0A5G2R2M6-1" }, "locus": { "chromosome": "9", "start_pos": 36504263, "end_pos": 36436298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078414.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078414.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068452.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068452.1" } ] } }, { "isoform_ac": "A0A8W4FQC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6/entry#A0A8W4FQC8-1", "sequence": { "sequence": "MATSNLLKNKGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILAYIVEWRKFFTQCDILPKPFCQLEITLMGKQGSNKKSNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA", "length": 759, "header": "tr|A0A8W4FQC8-1|A0A5G2R2M6_PIG Computationally mapped isoform of Cullin-5 OS=Sus scrofa OX=9823 GN=CUL5 PE=1 SV=1 CANONICAL=A0A5G2R2M6-1" }, "locus": { "chromosome": "9", "start_pos": 36504263, "end_pos": 36420299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102083.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102083.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080573.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080573.1" } ] } }, { "isoform_ac": "I3LFR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6/entry#I3LFR2-1", "sequence": { "sequence": "MATSNLLKNKGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLMGKQGSNKKSNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA", "length": 758, "header": "tr|I3LFR2-1|A0A5G2R2M6_PIG Computationally mapped isoform of Cullin-5 OS=Sus scrofa OX=9823 GN=CUL5 PE=1 SV=2 CANONICAL=A0A5G2R2M6-1" }, "locus": { "chromosome": "9", "start_pos": 36504263, "end_pos": 36420299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029949.4", "url": "https://www.ensembl.org/id/ENSSSCT00000029949.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022904.2", "url": "https://www.ensembl.org/id/ENSSSCP00000022904.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FQC8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQC8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8863795", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8863795", "resource": "Reactome", "description": "Downregulation of ERBB2 signaling" }, { "id": "R-SSC-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" }, { "name": "ubiquitin ligase complex scaffold activity", "id": "GO:0160072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160072", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" }, { "name": "negative regulation of focal adhesion assembly", "id": "GO:0051895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051895", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" }, { "name": "negative regulation of focal adhesion disassembly", "id": "GO:0120184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120184", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" }, { "name": "Cul5-RING ubiquitin ligase complex", "id": "GO:0031466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031466", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" }, { "name": "cullin-RING ubiquitin ligase complex", "id": "GO:0031461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031461", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2M6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 772, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2M6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2M6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M6" }, { "id": "PS50069", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50069" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cullin family profile", "eco_id": "ECO_0000259", "start_pos": 395, "end_pos": 630, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 557, "end_pos": 559 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R228-1", "uniprot_ac": "A0A5G2R228", "uniprot_id": "A0A5G2R228_PIG", "mass": { "chemical_mass": 118715.0, "monoisotopic_mass": 118715.0 }, "refseq": { "ac": "XP_020946393", "name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946393" }, "gene_names": [ { "name": "LRIG2", "type": "recommended", "evidence": [ { "id": "A0A5G2R228", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228" } ] }, { "name": "LRIG2", "type": "synonym", "evidence": [ { "id": "XP_020946393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946393" } ] } ], "protein_names": [ { "name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "type": "recommended", "evidence": [ { "id": "A0A5G2R228", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeats and immunoglobulin-like domains protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020946393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946393" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R228", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LRIG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228", "locus": { "chromosome": "4", "start_pos": 107348669, "end_pos": 107492516, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034581", "url": "https://www.ensembl.org/id/ENSSSCG00000034581" } ] } } ], "crossref": [ { "id": "A0A5G2R228", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R228", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034581", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034581", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05763", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05763", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100154795", "url": "https://www.ncbi.nlm.nih.gov/gene/100154795", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154795", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154795", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVTMNHN", "url": "https://omabrowser.org/oma/group/QVTMNHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R228", "url": "https://www.orthodb.org/?gene=A0A5G2R228", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF210", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF210", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020946393", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946393", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZNI0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZNI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R228", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R228-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4X0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4X0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASAPQGVREEQLLECGTGLFSRLLFLAQAVLLLLPAARASLCPAPCSCRIPLLDCSRRKLPAPSWRALSSSLPPDTASLDLSHNRLSNWNISLESQTLQEVKMNYNELTEIPYFGESTSNITLLSLVHNIIPEINAEVFQFYPALENLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITILEAGCFDNLSSSLLVVKLNRNRISMIPPKIFKLPHLQFLELKRNRIKVVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLDNMEELELEHNNLTEVNKGWLYGLRMLQQLYVSQNAVERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLNLRNNEISWAIEDASEAFSGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAITSIQENAFSQTRLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPETTVALRGMNVTLTCTAVSSSDSAMSAVWRKDSEILYDADIENFVRYQQQAGEALEYTSVLHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSSNCDSSQGSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYLHKGADGGTGTRVICSDCYDNANIYSRTREYCPYTYVAEEDVLEQTLSSLMVQMPKETYLAHPPQEATTLESLVSSADRGMSAFPSNHERINEKKLPSTQMSSETLQRPLWNISKDLGMPRAPFSQQPALESPQLHQNEGLAETDPDCSASPMPSRRLLDHAFDFSRTRNIQDGSEGT", "length": 1065, "header": "tr|A0A5G2R228-1|A0A5G2R228_PIG Isoform 1 of Leucine-rich repeats and immunoglobulin-like domains protein 2 OS=Sus scrofa OX=9823 GN=LRIG2 PE=4 SV=1 CANONICAL=A0A5G2R228-1" }, "isoforms": [ { "isoform_ac": "A0A286ZNI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228/entry#A0A286ZNI0-1", "sequence": { "sequence": "MNYNELTEIPYFGESTSNITLLSLVHNIIPEINAEVFQFYPALENLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITILEAGCFDNLSSSLLVVKLNRNRISMIPPKIFKLPHLQFLELKRNRIKVVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLDNMEELELEHNNLTEVNKGWLYGLRMLQQLYVSQNAVERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLNLRNNEISWAIEDASEAFSGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAITSIQENAFSQTRLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPETTVALRGMNVTLTCTAVSSSDSAMSAVWRKDSEILYDADIENFVRYQQQAGEALEYTSVLHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSSNCDSSQGSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYLHKGADGGTGTRVICSDCYDNANIYSRTREYCPYTYVAEEDVLEQTLSSLMVQMPKETYLAHPPQEATTLESLVSSADRGMSAFPSNHERINEKKLPSTQMSSETLQRPLWNISKDLGMPRAPFSQQPALESPQLHQNEGLAETDPDCSASPMPSRRLLDHAFDFSRTRNIQDGSEGT", "length": 962, "header": "tr|A0A286ZNI0-1|A0A5G2R228_PIG Computationally mapped isoform of Leucine-rich repeats and immunoglobulin-like domains protein 2 OS=Sus scrofa OX=9823 GN=LRIG2 PE=4 SV=2 CANONICAL=A0A5G2R228-1" }, "locus": { "chromosome": "4", "start_pos": 107382357, "end_pos": 107354075, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060304.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060304.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033030.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033030.2" } ] } }, { "isoform_ac": "A0A5G2R228-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228/entry#A0A5G2R228-1", "sequence": { "sequence": "MASAPQGVREEQLLECGTGLFSRLLFLAQAVLLLLPAARASLCPAPCSCRIPLLDCSRRKLPAPSWRALSSSLPPDTASLDLSHNRLSNWNISLESQTLQEVKMNYNELTEIPYFGESTSNITLLSLVHNIIPEINAEVFQFYPALENLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITILEAGCFDNLSSSLLVVKLNRNRISMIPPKIFKLPHLQFLELKRNRIKVVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLDNMEELELEHNNLTEVNKGWLYGLRMLQQLYVSQNAVERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLNLRNNEISWAIEDASEAFSGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAITSIQENAFSQTRLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPETTVALRGMNVTLTCTAVSSSDSAMSAVWRKDSEILYDADIENFVRYQQQAGEALEYTSVLHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSSNCDSSQGSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYLHKGADGGTGTRVICSDCYDNANIYSRTREYCPYTYVAEEDVLEQTLSSLMVQMPKETYLAHPPQEATTLESLVSSADRGMSAFPSNHERINEKKLPSTQMSSETLQRPLWNISKDLGMPRAPFSQQPALESPQLHQNEGLAETDPDCSASPMPSRRLLDHAFDFSRTRNIQDGSEGT", "length": 1065, "header": "tr|A0A5G2R228-1|A0A5G2R228_PIG Isoform 1 of Leucine-rich repeats and immunoglobulin-like domains protein 2 OS=Sus scrofa OX=9823 GN=LRIG2 PE=4 SV=1 CANONICAL=A0A5G2R228-1" }, "locus": { "chromosome": "4", "start_pos": 107416692, "end_pos": 107354075, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073157.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073157.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071241.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071241.1" } ] } }, { "isoform_ac": "A0A5G2R4X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228/entry#A0A5G2R4X0-1", "sequence": { "sequence": "MASAPQGAVLLLLPAARASLCPAPCSCRIPLLDCSRRKLPAPSWRALSSSLPPDTASLDLSHNRLSNWNISLESQTLQEVKMNYNELTEIPYFGESTSNITLLSLVHNIIPEINAEVFQFYPALENLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITILEAGCFDNLSSSLLVVKLNRNRISMIPPKIFKLPHLQFLELKRNRIKVVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLDNMEELELEHNNLTEVNKGWLYGLRMLQQLYVSQNAVERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLNLRNNEISWAIEDASEAFSGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAITSIQENAFSQTRLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPETTVALRGMNVTLTCTAVSSSDSAMSAVWRKDSEILYDADIENFVRYQQQAGEALEYTSVLHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSSNCDSSQGSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYLHKGADGGTGTRVICSDCYDNANIYSRTREYCPYTYVAEEDVLEQTLSSLMVQMPKETYLAHPPQEATTLESLVSSADRGMSAFPSNHERINEKKLPSTQMSSETLQRPLWNISKDLGMPRAPFSQQPALESPQLHQNEGLAETDPDCSASPMPSRRLLDHAFDFSRTRNIQDGSEGT", "length": 1043, "header": "tr|A0A5G2R4X0-1|A0A5G2R228_PIG Computationally mapped isoform of Leucine-rich repeats and immunoglobulin-like domains protein 2 OS=Sus scrofa OX=9823 GN=LRIG2 PE=4 SV=1 CANONICAL=A0A5G2R228-1" }, "locus": { "chromosome": "4", "start_pos": 107416692, "end_pos": 107354075, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084180.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084180.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071378.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071378.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4X0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4X0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154795", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154795", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQV2-1", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "gene_name": "Lrig2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAPRGVWEQRRLGCRLGPLAPLLMLAQALLLLPAAGAGLCPAPCSCRLPLLDCSRRKLPALSWRALSGPLSPDISSLDLSHNRLSNWNISLESETLQEVKMNYNELTEIPYFGEPTPNITQLSLVHNLIPEINAEAFQLYSALESLDLSSNIISEIKTSSFPRMSLKYLNLSNNRITTLEAGCFDNLSGSLLVVKLNRNRISMIPPKVFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTGVHKGWLYGLRMLQQLYVSQNAIEKISPDAWEFCQRLSALDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEVFSGLKSLTKLILQGNRIKSVTQKAFVGLESLEYLDLNNNAIMSIQENAFSQTHLKELVLNTSSLLCDCHLKWLLQWLVDNNFHHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPENTVALRGVNVTLMCTAVSSSDSPMSTLWRKDSEILYDVDIENFVRYRQQDGEALEYTSVLRLFSVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPTPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCLMSNTLGTERGHIYLNVISSPNCDSSQNSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKDEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPASGYTHKGTDGGTGTRVICSDCYDNANIYSRTREYCPYTYIAEEDALDQALSSLMVQMPKETFLSHPPQDAANLESLMPPTERELSAFPTNHERTSENLPFSQRSSEIFQRPLWNMNRDLGLLPFPQQPVLESPQLAERDPNCSSPVSCHRLHDHAFDFSRTRNIQDGTEGT", "length": 1054 }, "evidence": [ { "id": "A0A5G2R228", "url": "https://omabrowser.org/oma/group/A0A5G2R228/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BIT3-1", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "gene_name": "LRIG2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPAPQGVREEPLLECGSRLLSRLLFLAQAVVLLLPAARAGLCPVPCSCRIPLLDCSRRKLPAPSWRALSTSLPPDAVSLDLSHNRLSNWNISLESQTLQEVLLRLLYSRLKTRKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAEVFQFYPALETLDLSSNQISEIKTSSFPRMQLKYLNLSNNRITVLEAGCFDNLSSSLLVVKLNRNRISMIPPKIFKLPHLQFLELKRNRIKVVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLDNMEELELEHNNLTEVNKGWLYGLRMLQQLYVSQNAVERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLNLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSVTKKAFIGLESLEHLDLNNNAIMSIQENAFSQTRLKELILNTNSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDLLKPQIRTHPETTVALRGVNVTLRCTAVSSSDSPMSALWRKDSEVLYDADIENFVRYQQQAGEALEYTSVLHLFNVNFTDEGKYQCIITNHFGSNYSHKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLIVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLDDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYLHKGTDGGAGTRVICSDCYDNANIYSRTREYCPYTYITEEDVLDQTLSSLMVQMPKETYLAHPPQDATTLESLVSSAERERCAFPTNHERMNEKKPSSTRMSNETLQRPLWNVSREPGMPHPPFPQQSVLESSQLHQNEGLAESDPDCSTSPMPCHRLHDHTFDFSRTRNVHNGSEGT", "length": 1077 }, "evidence": [ { "id": "A0A5G2R228", "url": "https://omabrowser.org/oma/group/A0A5G2R228/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O94898-1", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "gene_name": "LRIG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPAPLGVPEEQLLGCRSRVLSRLLFIAQTALLLLPAAGAGLCPAPCSCRIPLLDCSRRKLPAPSWRALSGLLPPDTAILDFSHNRLSNWNISLESQTLQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQAGEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYIHKGTDGGTGTRVICSDCYDNANIYSRTREYCPYTYIAEEDVLDQTLSSLMVQMPKETYLVHPPQDTTALESLIPSANREPSAFPTNHERISEKKLPSTQMSGETLQRPVWNINRELGLPHPPFSQQPVHESPQLHQNEGLAGREPDCSASSMSCHRLQDHAFDFSRTRNIQDGSEGT", "length": 1065 }, "evidence": [ { "id": "A0A5G2R228", "url": "https://omabrowser.org/oma/group/A0A5G2R228/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q52KR2-1", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "gene_name": "Lrig2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAPRGIWEQRRLGCGLGPLARLLILAQALRLLPAARAGLCPAPCACRLPLLDCSRRKLPAPSWRALSGPLPSDISSLDLSHNRLSNWNNTLESQTLQEVKMNYNELTEIPYFGEPTPNITLLSLVHNLIPEINAEAFELYSALESLDLSSNIISEIKTSSFPRMSLKYLNLSNNRISTLEAGCFDNLSDSLLVVKLNRNRISMIPPKVFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTGVNKGWLYGLRMLQQLYMSQNAIEKISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNDISWAIEDASEAFSGLKSLTKLILQGNRIKSVTQKAFIGLESLEYLDLNNNAIMSIQENAFSQTHLKGLVLNTSSLLCDCHLKWLLQWLVDNNFHHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPESTIALRGVNVTLTCTAVSSSDSPMSTIWRKDSEILYDVDIENFVRYRQQDGEALEYTSVLRLFSVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPTPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCLMSNTLGTERGHIYLNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYTHRGTDGGAGTRVICSDCYDNANIYSRTREYCPYTYIAEEDVLDQALSSLMVQMPKETFLSHPPQDAANLESLIPSAEREPAAFPTNHERMTENLPFSQRSSEIFQRPLWNMNRELGLLPFSQQPVLESPELTERDPNCSSPVTCRRLHDHAFDFSRTRIIQDGTEGT", "length": 1054 }, "evidence": [ { "id": "A0A5G2R228", "url": "https://omabrowser.org/oma/group/A0A5G2R228/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R228", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228" } ], "pmid": "" }, { "name": "intracellular vesicle", "id": "GO:0097708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097708", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R228", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R228", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R228", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R228", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R228", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R228", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 589, "end_pos": 591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" }, { "start_pos": 999, "end_pos": 1001, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R228-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1065, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R228-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R228" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R228", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R228" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 498, "end_pos": 597, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 173, "end_pos": 175 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 441, "end_pos": 443 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 589, "end_pos": 591 }, { "start_pos": 687, "end_pos": 689 }, { "start_pos": 728, "end_pos": 730 }, { "start_pos": 91, "end_pos": 93 }, { "start_pos": 999, "end_pos": 1001 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2V2-1", "uniprot_ac": "A0A5G2R2V2", "uniprot_id": "A0A5G2R2V2_PIG", "mass": { "chemical_mass": 24032.0, "monoisotopic_mass": 24032.0 }, "refseq": { "ac": "NP_001230488", "name": "large ribosomal subunit protein mL40 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230488" }, "gene_names": [ { "name": "MRPL40", "type": "recommended", "evidence": [ { "id": "A0A5G2R2V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2V2" } ] }, { "name": "MRPL40", "type": "synonym", "evidence": [ { "id": "NP_001230488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230488" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein mL40", "type": "recommended", "evidence": [ { "id": "A0A5G2R2V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2V2/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L40, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001230488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230488" }, { "id": "A0A5G2R2V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2V2/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein mL40 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001230488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230488" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2V2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2V2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MRPL40", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2V2", "locus": { "chromosome": "14", "start_pos": 51105767, "end_pos": 51102613, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034014", "url": "https://www.ensembl.org/id/ENSSSCG00000034014" } ] } } ], "crossref": [ { "id": "A0A5G2R2V2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2V2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034014", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034014", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100155568", "url": "https://www.ncbi.nlm.nih.gov/gene/100155568", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "6GAW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6GAW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6GB2", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6GB2&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6YDP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6YDP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6YDW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6YDW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NQH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NQH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NQL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NQL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NSH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NSH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NSI", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NSI&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NSJ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NSJ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8OIN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OIN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8OIQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OIQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR019192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155568", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155568", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KEWARYK", "url": "https://omabrowser.org/oma/group/KEWARYK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZP98", "url": "https://www.orthodb.org/?gene=A0A286ZP98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R2V2", "url": "https://www.orthodb.org/?gene=A0A5G2R2V2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13359:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13359:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00006gaw", "url": "https://www.rcsb.org/structure/pdb_00006gaw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006gb2", "url": "https://www.rcsb.org/structure/pdb_00006gb2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006ydp", "url": "https://www.rcsb.org/structure/pdb_00006ydp", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006ydw", "url": "https://www.rcsb.org/structure/pdb_00006ydw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nqh", "url": "https://www.rcsb.org/structure/pdb_00007nqh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nql", "url": "https://www.rcsb.org/structure/pdb_00007nql", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nsh", "url": "https://www.rcsb.org/structure/pdb_00007nsh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nsi", "url": "https://www.rcsb.org/structure/pdb_00007nsi", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nsj", "url": "https://www.rcsb.org/structure/pdb_00007nsj", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008oin", "url": "https://www.rcsb.org/structure/pdb_00008oin", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008oiq", "url": "https://www.rcsb.org/structure/pdb_00008oiq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6GAW", "url": "https://www.rcsb.org/structure/6GAW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6GB2", "url": "https://www.rcsb.org/structure/6GB2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6YDP", "url": "https://www.rcsb.org/structure/6YDP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6YDW", "url": "https://www.rcsb.org/structure/6YDW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NQH", "url": "https://www.rcsb.org/structure/7NQH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NQL", "url": "https://www.rcsb.org/structure/7NQL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NSH", "url": "https://www.rcsb.org/structure/7NSH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NSI", "url": "https://www.rcsb.org/structure/7NSI", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NSJ", "url": "https://www.rcsb.org/structure/7NSJ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OIN", "url": "https://www.rcsb.org/structure/8OIN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OIQ", "url": "https://www.rcsb.org/structure/8OIQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF09812", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09812", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230488", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230488", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZP98", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZP98-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2V2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2V2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAALGAASRTLRPASRLVGAWPTQTRDAHERGSLFSFWGLVPMRAEPLRKKKKVDPKKDQAAKDRLKKRIRRLEKASQELIPIEDFITPVKFLNKERQRPPVELPFEESERRALLLKRWSLYKQREHEMERSAIRSLLEAQEEALQELRLSSPELHAEATKRDPSLFPFERQGPDYTPPISDYQPPEGRYQDITKVYTQVEFKK", "length": 206, "header": "tr|A0A5G2R2V2-1|A0A5G2R2V2_PIG Isoform 1 of Large ribosomal subunit protein mL40 OS=Sus scrofa OX=9823 GN=MRPL40 PE=1 SV=1 CANONICAL=A0A5G2R2V2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZP98-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2V2/entry#A0A286ZP98-1", "sequence": { "sequence": "MRAEPLRKKKKVDPKKDQAAKDRLKKRIRRLEKASQELIPIEDFITPVKFLNKERQRPPVELPFEESERRALLLKRWSLYKQREHEMERSAIRSLLEAQEEALQELRLSSPELHAEATKRDPSLFPFERQGPDYTPPISDYQPPEGRYQDITKVYTQVEFKK", "length": 162, "header": "tr|A0A286ZP98-1|A0A5G2R2V2_PIG Computationally mapped isoform of Large ribosomal subunit protein mL40 OS=Sus scrofa OX=9823 GN=MRPL40 PE=1 SV=2 CANONICAL=A0A5G2R2V2-1" }, "locus": { "chromosome": "14", "start_pos": 51105677, "end_pos": 51103448, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046318.2", "url": "https://www.ensembl.org/id/ENSSSCT00000046318.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033416.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033416.2" } ] } }, { "isoform_ac": "A0A5G2R2V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2V2/entry#A0A5G2R2V2-1", "sequence": { "sequence": "MAAAALGAASRTLRPASRLVGAWPTQTRDAHERGSLFSFWGLVPMRAEPLRKKKKVDPKKDQAAKDRLKKRIRRLEKASQELIPIEDFITPVKFLNKERQRPPVELPFEESERRALLLKRWSLYKQREHEMERSAIRSLLEAQEEALQELRLSSPELHAEATKRDPSLFPFERQGPDYTPPISDYQPPEGRYQDITKVYTQVEFKK", "length": 206, "header": "tr|A0A5G2R2V2-1|A0A5G2R2V2_PIG Isoform 1 of Large ribosomal subunit protein mL40 OS=Sus scrofa OX=9823 GN=MRPL40 PE=1 SV=1 CANONICAL=A0A5G2R2V2-1" }, "locus": { "chromosome": "14", "start_pos": 51105677, "end_pos": 51103223, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074351.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074351.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070667.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070667.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.", "journal": "Nature", "date": "2018", "authors": "Kummer Eva, Leibundgut Marc, Rackham Oliver, Lee Richard G, Boehringer Daniel, Filipovska Aleksandra, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP98", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP98" } ], "reference": [ { "type": "PubMed", "id": "30089917", "url": "https://glygen.org/publication/PubMed/30089917" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP98", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP98" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Structural insights into mammalian mitochondrial translation elongation catalyzed by mtEFG1.", "journal": "EMBO J.", "date": "2020", "authors": "Kummer E, Ban N", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP98", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP98" } ], "reference": [ { "type": "PubMed", "id": "32602580", "url": "https://glygen.org/publication/PubMed/32602580" } ] }, { "title": "Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.", "journal": "Mol. Cell", "date": "2021", "authors": "Kummer Eva, Schubert Katharina Noel, Schoenhut Tanja, Scaiola Alain, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP98", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP98" } ], "reference": [ { "type": "PubMed", "id": "33878294", "url": "https://glygen.org/publication/PubMed/33878294" } ] }, { "title": "Molecular basis of translation termination at noncanonical stop codons in human mitochondria.", "journal": "Science", "date": "2023", "authors": "Saurer Martin, Leibundgut Marc, Nadimpalli Hima Priyanka, Scaiola Alain, Sch\u00f6nhut Tanja, Lee Richard G, Siira Stefan J, Rackham Oliver, Dreos Ren\u00e9, Lenar\u010di\u010d Tea, Kummer Eva, Gatfield David, Filipovska Aleksandra, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP98", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP98" } ], "reference": [ { "type": "PubMed", "id": "37141370", "url": "https://glygen.org/publication/PubMed/37141370" } ] } ], "pathway": [ { "id": "ssc:100155568", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155568", "resource": "KEGG Pathway" }, { "id": "R-SSC-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-SSC-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-SSC-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZZP5-1", "protein_name": "Large ribosomal subunit protein mL40", "gene_name": "MRPL40", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDPIAQRRVSVSPFCFDVIQFKAACQLAAALREAALRHEGSLCTCGSAALRRAQPKKKKKVDPKREQAQKDRVKKKIKKLEKAAPELIPIEDFETPLKFSDSNRVRSLPPLSFEETERRVLLMKKWSLYKQQQDKAEKEAIQSLVEAQQEALKELRLESEELYQAAVRRDEELFPFERDGPNYTPPLPGYDPPEGKCIDITKVYTQ", "length": 206 }, "evidence": [ { "id": "A0A5G2R2V2", "url": "https://omabrowser.org/oma/group/A0A5G2R2V2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HEN4-1", "protein_name": "Large ribosomal subunit protein mL40", "gene_name": "Mrpl40", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTTAVMLCAARALRPLSWIPGICQTQTRHTHQRASLLSFWELIPMRAEPLRKKKKVDPRKDQAAKDRLKRRIRKLERANQELIPIEDFITPLRFLDKSRKRPQEEHSFEESEQRALLLKRWALYKKQEHEAERDAIRAMLEAQQEALQELKLESPELYEEAIKRDPSLFPFEKEGPHHTPPISNYQAPEGRYNDITKVYAQVESKR", "length": 206 }, "evidence": [ { "id": "A0A5G2R2V2", "url": "https://omabrowser.org/oma/group/A0A5G2R2V2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P83565-1", "protein_name": "Large ribosomal subunit protein mL40", "gene_name": "Mrpl40", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATAAMLCAARALRPRSWIPGTCQAQVRHTHQRASLLSFWELIPMRAEPLRKKKKVDPRKDQAAKDRLKKRIRKLERASQELVPIEDFITPVRFLDKSRQRPQEEHSFEESERRALLLKRWALYKQQEHEMERDAIRAMLEAQQEALEQLKLESTELYAEAIKRDTSLFPFEKEGPHYTPPVPNYQAPEGRYNDITKVYTQVEFKR", "length": 206 }, "evidence": [ { "id": "A0A5G2R2V2", "url": "https://omabrowser.org/oma/group/A0A5G2R2V2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NQ50-1", "protein_name": "Large ribosomal subunit protein mL40", "gene_name": "MRPL40", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTASVLRSISLALRPTSGLLGTWQTQLRETHQRASLLSFWELIPMRSEPLRKKKKVDPKKDQEAKERLKRKIRKLEKATQELIPIEDFITPLKFLDKARERPQVELTFEETERRALLLKKWSLYKQQERKMERDTIRAMLEAQQEALEELQLESPKLHAEAIKRDPNLFPFEKEGPHYTPPIPNYQPPEGRYNDITKVYTQVEFKR", "length": 206 }, "evidence": [ { "id": "A0A5G2R2V2", "url": "https://omabrowser.org/oma/group/A0A5G2R2V2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VGP7-1", "protein_name": "Large ribosomal subunit protein mL40", "gene_name": "mRpL40", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLLGAFARLSLQRSGGVAGAAFARCLHTTPVLCAEPLKKKKKLDPQIVKQREDRKKKKIEKQIRRLEKNARQLKPVDELEVPLELIDEKDKRQRKLAPLTIDQLEERALLKKQWAHYKHDERVADFQIIDRLVQAQNKALAELRRESEELYQAAIDIDPQLLPVAVKGPVATPPIKDYVSPDGDYLHQSMKWEVK", "length": 196 }, "evidence": [ { "id": "A0A5G2R2V2", "url": "https://omabrowser.org/oma/group/A0A5G2R2V2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z2Q5-1", "protein_name": "Large ribosomal subunit protein mL40", "gene_name": "Mrpl40", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATGVMLCAARALRPRSWIPGTCQAHVRHTHQRASLLAFWDLIPMRAEPLRKKKKVDPRKDQAAKDRLKKRIRKLEKASQELIPIEDFITPVRFLDKSRQRPQEEHSPEESERRALLLKRWALFKQQEHEMERDAIRSMLEAQQEALEELKLESAELYAEAIKRDTSLFPFEKEGPHYTPPISNYQAPEGRYNDITKVYTQVEFKR", "length": 206 }, "evidence": [ { "id": "A0A5G2R2V2", "url": "https://omabrowser.org/oma/group/A0A5G2R2V2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2V2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2V2" } ], "pmid": "" }, { "name": "mitochondrial ribosome", "id": "GO:0005761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005761", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2V2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2V2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2V2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 206, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2V2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2V2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWR3-1", "uniprot_ac": "A0A5G2QWR3", "uniprot_id": "A0A5G2QWR3_PIG", "mass": { "chemical_mass": 44973.0, "monoisotopic_mass": 44973.0 }, "refseq": { "ac": "XP_003354580", "name": "zinc finger protein 764 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354580" }, "gene_names": [ { "name": "ZNF764", "type": "recommended", "evidence": [ { "id": "A0A5G2QWR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3" } ] }, { "name": "ZNF764", "type": "synonym", "evidence": [ { "id": "XP_003354580", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354580" } ] } ], "protein_names": [ { "name": "Zinc finger protein 764", "type": "synonym", "evidence": [ { "id": "A0A5G2QWR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 764 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003354580", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354580" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF764", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3", "locus": {} } ], "crossref": [ { "id": "A0A5G2QWR3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000038852", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000038852", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100620532", "url": "https://www.ncbi.nlm.nih.gov/gene/100620532", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100620532", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620532", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RRHGCYV", "url": "https://omabrowser.org/oma/group/RRHGCYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZR79", "url": "https://www.orthodb.org/?gene=A0A286ZR79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QWR3", "url": "https://www.orthodb.org/?gene=A0A5G2QWR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003354580", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354580", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZR79", "url": "https://www.uniprot.org/uniprotkb/A0A286ZR79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZR79-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZR79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPPAPLPTREPNGAGGQWGTPEPVKFADVAVYFSPEEWAYLRPAQKALYRDVMRETYGLLGALGFRGTKPALISWVEQEAELWGLEARDPEVGECLTEADTGSRDQEEKRQREETEALGKIFSVDAQPPGLTALKPLSAGFSGGWEQPSKMPRRGRPPLCAHPPVPRADQRHGCYVCGKSFAWRSTLVEHLYMHKGQKPFCCPDCGKGFSQASSLSKHRALHRGERPHRCPDCGRAFTQRSALTTHLRVHTGEKPYRCADCGRCFSQSSALYQHQRVHSGETPFPCRDCGRAFAHASDLRRHMRTHTGEKPYPCPDCGRGFRQNSEMAAHRRTHSGERPYPCPQCGRCFGQKSAVAKHQWVHRPGAGGRGGRAASGVPTPLASGGGGDLDPPVGFQHYPEIFQECG", "length": 408, "header": "tr|A0A5G2QWR3-1|A0A5G2QWR3_PIG Isoform 1 of Zinc finger protein 764 OS=Sus scrofa OX=9823 GN=ZNF764 PE=3 SV=1 CANONICAL=A0A5G2QWR3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZR79-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3/entry#A0A286ZR79-1", "sequence": { "sequence": "MAPPPAPLPTREPNGAGGQWGTPEPVKFADVAVYFSPEEWAYLRPAQKALYRDVMRETYGLLGALGSRDQEEKRQREETEALGKIFSVDAQPPGLTALKPLSAGFSGGWEQPSKMPRRGRPPLCAHPPVPRADQRHGCYVCGKSFAWRSTLVEHLYMHKGQKPFCCPDCGKGFSQASSLSKHRALHRGERPHRCPDCGRAFTQRSALTTHLRVHTGEKPYRCADCGRCFSQSSALYQHQRVHSGETPFPCRDCGRAFAHASDLRRHMRTHTGEKPYPCPDCGRGFRQNSEMAAHRRTHSGERPYPCPQCGRCFGQKSAVAKHQWVHRPGAGGRGGRAASGVPTPLASGGGGDLDPPVGFQHYPEIFQECG", "length": 370, "header": "tr|A0A286ZR79-1|A0A5G2QWR3_PIG Computationally mapped isoform of Zinc finger protein 764 OS=Sus scrofa OX=9823 GN=ZNF764 PE=3 SV=1 CANONICAL=A0A5G2QWR3-1" }, "locus": { "chromosome": "3", "start_pos": 17804537, "end_pos": 17801461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052912.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052912.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034127.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034127.1" } ] } }, { "isoform_ac": "A0A5G2QWR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3/entry#A0A5G2QWR3-1", "sequence": { "sequence": "MAPPPAPLPTREPNGAGGQWGTPEPVKFADVAVYFSPEEWAYLRPAQKALYRDVMRETYGLLGALGFRGTKPALISWVEQEAELWGLEARDPEVGECLTEADTGSRDQEEKRQREETEALGKIFSVDAQPPGLTALKPLSAGFSGGWEQPSKMPRRGRPPLCAHPPVPRADQRHGCYVCGKSFAWRSTLVEHLYMHKGQKPFCCPDCGKGFSQASSLSKHRALHRGERPHRCPDCGRAFTQRSALTTHLRVHTGEKPYRCADCGRCFSQSSALYQHQRVHSGETPFPCRDCGRAFAHASDLRRHMRTHTGEKPYPCPDCGRGFRQNSEMAAHRRTHSGERPYPCPQCGRCFGQKSAVAKHQWVHRPGAGGRGGRAASGVPTPLASGGGGDLDPPVGFQHYPEIFQECG", "length": 408, "header": "tr|A0A5G2QWR3-1|A0A5G2QWR3_PIG Isoform 1 of Zinc finger protein 764 OS=Sus scrofa OX=9823 GN=ZNF764 PE=3 SV=1 CANONICAL=A0A5G2QWR3-1" }, "locus": { "chromosome": "3", "start_pos": 17804537, "end_pos": 17801461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081077.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081077.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069306.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069306.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZR79", "url": "https://www.uniprot.org/uniprotkb/A0A286ZR79" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100620532", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620532", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZM47-1", "protein_name": "Zinc finger protein 764", "gene_name": "Zfp764", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQRITPGRASAQPEFYKPGTVSFSDVAVYFSSEEWRCLQPAERALYREVMRETYGLLGSFGIRGAKPALICWVEEETELWGPRAQDPEVAMCKTEVHSDCRQEEKRRKPREETEAIQRTFSTEAGPKEPCPSFAASPSYLELLSKDPQQGQPTVPLHDTVLKADQRHGCHVCGKSFTRQSKLVEHLYTHTGEKPFQCSECNKCFGRASSLSMHRAIHRRERPHCCPDCGKSFTQRSTLVAHMYTHTGEKPFRCPDCNKSFSWPSSLSTHRAIHRGERPHCCPDCGRAFTHRSGLITHLRVHTGEKPYCCADCGRCFSQSSGLSEHQRVVHSGMTPFSCTHCGRAFARAAYLRCHMRTHTGEKPYSCPDCGRCFRQGSDMAAHRRTHSGERPYPCPQCGRGFPTKSAMTKHQWVHRPGAKGHRDRKASQLSVALGTGQEDPDPPVGFQLYPEIFQECGAWS", "length": 461 }, "evidence": [ { "id": "A0A5G2QWR3", "url": "https://omabrowser.org/oma/group/A0A5G2QWR3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PZQ8-1", "protein_name": "Zinc finger protein 764 like 1", "gene_name": "Zfp764l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPRMAPERASAWPAFLKPGTVSFADVAVYFSPEEWRCLRPAQRTLYREVMRETYGLLASLEVGGDKPALICWVEEESEVWGPGAQEPEVAMCRTEVHSDCRHEKEGKRPREETKATKKILSPEAGPMEPRPSFASPSCNLELLFKNSQQGHPTVAVHNPILKADQRHGCHVCGKSFAHQSKLVEHLYTHTGEKPFQCPDCDKYFGRASSLSMHRAIHRGERPHQCPDCGKSFTQRSTLVAHMYTHTGEKPFHCPDCNKSFSRPSSLSSHRAIHRGERPHCCSDCGRAFTHRSGLIAHLRVHTGEKPYCCADCGRCFSQSSGLREHQRVVHSGVTPFTCTHCGRAFARAAYLQCHMRTHTGEKPYSCPDCGRCFRQSSDMAAHRRTHSGERPYPCPQCGRRFPTKSAVTKHQWVHRPGAKGHKDKKFSQLSISLDPSQEDPDPPVGFQHYPEIFQECGGWS", "length": 461 }, "evidence": [ { "id": "A0A5G2QWR3", "url": "https://omabrowser.org/oma/group/A0A5G2QWR3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96H86-1", "protein_name": "Zinc finger protein 764", "gene_name": "ZNF764", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPPLAPLPPRDPNGAGPEWREPGAVSFADVAVYFCREEWGCLRPAQRALYRDVMRETYGHLSALGIGGNKPALISWVEEEAELWGPAAQDPEVAKCQTQTDPADSRNKKKERQREGTGALEKPDPVAAGSPGLKSPQAPSAGPPYGWEQLSKAPHRGRPSLCAHPPVPRADQRHGCYVCGKSFAWRSTLVEHVYSHTGEKPFHCTDCGKGFGHASSLSKHRAIHRGERPHRCLECGRAFTQRSALTSHLRVHTGEKPYGCADCGRRFSQSSALYQHRRVHSGETPFPCPDCGRAFAYPSDLRRHVRTHTGEKPYPCPDCGRCFRQSSEMAAHRRTHSGEKPYPCPQCGRRFGQKSAVAKHQWVHRPGAGGHRGRVAGRLSVTLTPGHGDLDPPVGFQLYPEIFQECG", "length": 408 }, "evidence": [ { "id": "A0A5G2QWR3", "url": "https://omabrowser.org/oma/group/A0A5G2QWR3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWR3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 408, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWR3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWR3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 201, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QWR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR3" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 97, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWN3-1", "uniprot_ac": "A0A5G2QWN3", "uniprot_id": "A0A5G2QWN3_PIG", "mass": { "chemical_mass": 182957.0, "monoisotopic_mass": 182957.0 }, "refseq": {}, "gene_names": [ { "name": "ABI3BP", "type": "recommended", "evidence": [ { "id": "A0A5G2QWN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3" } ] } ], "protein_names": [ { "name": "ABI family member 3 binding protein", "type": "synonym", "evidence": [ { "id": "A0A5G2QWN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ABI3BP", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3", "locus": { "chromosome": "13", "start_pos": 158291103, "end_pos": 158013726, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011959", "url": "https://www.ensembl.org/id/ENSSSCG00000011959" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011959", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011959", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100154641", "url": "https://www.ncbi.nlm.nih.gov/gene/100154641", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23197", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23197", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23197:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23197:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21731", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21731", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZYL3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A2L7", "url": "https://www.uniprot.org/uniprotkb/A0A287A2L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A2L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2L7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AQF9", "url": "https://www.uniprot.org/uniprotkb/A0A287AQF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AQF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QEI5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QEI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIF2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUX0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RB21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RB21-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SL03", "url": "https://www.uniprot.org/uniprotkb/F1SL03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SL03-1", "url": "https://www.uniprot.org/uniprotkb/F1SL03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSSLGCLLLCGSIALALGNAQKLPKGKKPNLKVHINTTSDSIFLKFLRPHPNVKLEGFLLGYGSNLSPNQYFPLPAEGKYTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPQHDWTLPSQCPNDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPDTVYEFGVKDNVEGGIWSKIFNHKTIVGSKGKVNGKIQSTYDQVHTVPSYVPRKVIPVTIIKQVIQNVTHKASAKSPDRTPYGGTILVHLVIPGLNETTVKLPTSIMFDISNALKTELAKNETLALPAESKTPEVEKIPAQPITATPESVPRTTKPTASSALDISETTLAPKSLPEFPQAKTPFPFEKSWGTLASSEKPWIVPTSKTSEDSKILPPQTATSDPFLDSLPRKTSRTLEQPRATLAPSETPFVPPELEIFTSPEMQPTTSAPLQTTSIPSTPKRRLRPKIPRTKPERTTRPGIITSKISKSPEPTWTTLAPSKTPFISLKPKIPLSPEVTHTKPAPEPETPPPSPPPIVLEPGTLGTKPSTTLAPPKTKRPGRRPRPRPKTTPSPDVPKSKPALEPATVQPEPLGPTVDSKPPKQLLPKPQTTAKPDMPPPKSVLEPVTSEPEEPSTTIVPDTDIEPVTLRTEALPTTLAPKTSQRTRTRRPRPRPKPKTTPSPETPQAKLDFEPVTPGTSLATTTTTTTKRPRRPRPKLKTTPHPEVPQTKLVPATTPEPVTLRTEAPGTTIAPKVPQRTRHPRPKPKTTPSPEAPHTEPVPATDLEPVTPIKEAPVPVTDLEPVTFPTEISGTTLATKASQRPRRPRPRPKTTPSPQVPHTKPVPATALEPVTLKPEARGTTLVPTAVFEPVTLRTEAWVMTRAPKTSKRTRRPCPKPKTTPTPEAPRFKPVSTTDLVPGTEAPEIMALPTVLEPVIFRTKTPETTLVPAMSFEPVTYSSKAPETTLAPIELQTLTLKPVTSPSLDMTQSQPVSEVVESVTFSTESSKEAIVPTETDYPTAKVPLRPEEPKTEVVESITYVSEPPETMLVTIETSPLPSQTIILPSPDEPQTEPAPKQTPRTPPKPKTSPRPRIPQTQPVPKVFQRVTPKPKTSPSPEVSYTPSVPRDVFLPHKPDPEVSQSEPVLQPVTFRIDLPESTIAPLETRGSPFIPMISPSSSQEELQTTLETDQSTQELFTTKLPRTTELAKTTQAPHRLFTTPVRPRTPDKPHVRPVLNKTTTRPSRPKPSGMPRGNGIGTGIKQTPLPSGPGRNVSLDSTHSTKKPAMIPGTRRPPLPPRPTPPRRKPLPPNNVTGKPGSAGIISSGRVTSPPLRATLRPTEAPLERIETDKKQPTAPASGEDLGNMTDFSSSPTRETDPLGKPRFKGPHVRYIQKPENRPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWDKPLNDTVTEYEVISRENGSFSGKNKSIQTTNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLSSDQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW", "length": 1668, "header": "tr|A0A5G2QWN3-1|A0A5G2QWN3_PIG Isoform 1 of ABI family member 3 binding protein OS=Sus scrofa OX=9823 GN=ABI3BP PE=1 SV=1 CANONICAL=A0A5G2QWN3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZYL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3/entry#A0A286ZYL3-1", "sequence": { "sequence": "MLSSLGCLLLCGSIALALGNAQKLPKGKKPNLKVHINTTSDSIFLKFLRPHPNVKLEGFLLGYGSNLSPNQYFPLPAEGKYTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPQHDWTLPSQCPNDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPDTVYEFGVKDNVEGGIWSKIFNHKTIVGSKGKVNGKIQSTYDQVHTVPSYVPRKVIPVTIIKQVIQNVTHKASAKSPDRTPYGGTILVHLVIPGLNETTVKLPTSIMFDISNALKTELAKNETLALPAESKTPEVEKIPAQPITATPESVPRTTKPTASSALDISETTLASSEKPWIVPTSKTSEDSKILPPQTATSDPFLDSLPRKTSRTLEQPRATLAPSETPFVPPELEIFTSPEMQPTTSAPLQTTSIPSTPKRRLRPKIPRTKPERTTRPGIITSKISKSPEPTWTTLAPSKTPFISLKPKIPLSPEVTHTKPAPEPETPPPSPPPIVLEPGTLGTKPSTTLAPPKTKRPGRRPRPRPKTTPSPDVPKSKPALEPATVQPEPLGPTVDSKPPKQLLPKPQTTAKPDMPPPKSVLEPVTSEPEEPSTTIVPDTDIEPVTLRTEALPTTLAPKTSQRTRTRRPRPRPKPKTTPSPETPQAKLDFEPVTPGTSLAPTATTTTTTTKRPRRPRPKLKTTPHPEVPQTKLVPATTPEPVTLRTEAPGTTIAPKVPQRTRHPRPKPKTTPSPEAPHTEPVPATDLEPVTPIKEAPVPVTDLEPVTFPTEISGTTLATKASQRPRRPRPRPKTTPSPQVPHTKPVPATALEPVTLKPEARGTTLVPTAVFEPVTLRTEAWVMTRAPKTSKRTRRPCPKPKTTPTPEAPRFKPAPKQTPRTPPKPKTSPRPRIPQTQPVPKVFQRVTPKPKTSPSPEVSYTPSVPRDVFLPHKPDPEVSQSEPVLQPVTFRIDLPESTIAPLETRGSPFIPMISPSSSQEELQTTLETDQSTQELFTTKLPRTTELAKTTQAPHRLFTTPVRPRTPDKPHVRPVLNKTTTRPSRPKPSGMPRGNGIGTGIKQTPLPSGPGRNVSLDSTHSTKKPAMIPGTRRPPLPPRPTPPRRKPLPPNNVTGKPGSAGIISSGRVTSPPLRATLRPTEAPLERIETDKKQPTAPASGEDLGNMTDFSSSPTRETDPLGKPRFKGPHVRYIQKPENRPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWDKPLNDTVTEYEVISRENGSFSGKNKSIQTTNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLSSDQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW", "length": 1484, "header": "tr|A0A286ZYL3-1|A0A5G2QWN3_PIG Computationally mapped isoform of ABI family member 3 binding protein OS=Sus scrofa OX=9823 GN=ABI3BP PE=1 SV=2 CANONICAL=A0A5G2QWN3-1" }, "locus": { "chromosome": "13", "start_pos": 158289650, "end_pos": 158013822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045758.2", "url": "https://www.ensembl.org/id/ENSSSCT00000045758.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036597.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036597.2" } ] } }, { "isoform_ac": "A0A287A2L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3/entry#A0A287A2L7-1", "sequence": { "sequence": "MLSSLGCLLLCGSIALALGNAQKLPKGKKPNLKVHINTTSDSIFLKFLRPHPNVKLEGFLLGYGSNLSPNQYFPLPAEGKYTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPQHDWTLPSQCPNDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPDTVYEFGVKDNVEGGIWSKIFNHKTIVGSKGKVNGKIQSTYDQVHTVPSYVPRKVIPVTIIKQVIQNVTHKASAKSPDRTPYGGTILVHLVIPGLNETTVKLPTSIMFDISNALKTELAKNETLALPAESKTPEVEKIPAQPITATPESVPRTTKPTASSALDISETTLASSEKPWIVPTSKTSEDSKILPPQTATSDPFLDSLPRKTSRTLEQPRATLAPSETPFVPPELEIFTSPEMQPTTSAPLQTTSIPSTPKRRLRPKIPRTKPERTTRPGIITSKISKSPEPTWTTLAPSKTPFISLKPKIPLSPEVTHTKPAPEPETPPPSPPPIVLEPGTLGTKPSTTLAPPKTKRPGRRPRPRPKTTPSPDVPKSKPALEPATVQPEPLGPTVVLEPVTSEPEEPSTTIVPDTDIEPVTLRTEALPTTLAPKTSQRTRTRRPRPRPKPKTTPSPETPQAKLDFEPVTPGTSLVPATTPEPVTLRTEAPGTTIAPKVPQRTRHPRPKPKTTPSPEAPHTEPVPATDLEPVTPIKEAPVPVTDLEPVTFPTEISGTTLATKASQRPRRPRPRPKTTPSPQVPHTKPVPATALEPVTLKPEARGTTLVPTAVFEPVTLRTEAWVMTRAPKTSKRTRRPCPKPKTTPTPEAPRFKPVSTTDLVPGTEAPEIMALPTVLEPVIFRTKTPETTLAPKQTPRTPPKPKTSPRPRIPQTQPVPKVFQRVTPKPKTSPSPEVSYTPSVPRDVFLPHKPDPEVSQSEPVLQPVTFRIDLPESTIAPLETRGSPFIPMISPSSSQEELQTTLETDQSTQELFTTKLPRTTELAKTTQAPHRLFTTPVRPRTPDKPHVRPVLNKTTTRPSRPKPSGMPRGNGIGTGIKQTPLPSGPGRNVSLDSTHSTKKPAMIPGTRRPPLPPRPTPPRRKPLPPNNVTGKPGSAGIISSGRVTSPPLRATLRPTEAPLERIETDKKQPTAPASGEDLGNMTDFSSSPTRETDPLGKPRFKGPHVRYIQKPENRPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWDKPLNDTVTEYEVISRENGSFSGKNKSIQTTNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLSSDQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW", "length": 1461, "header": "tr|A0A287A2L7-1|A0A5G2QWN3_PIG Computationally mapped isoform of ABI family member 3 binding protein OS=Sus scrofa OX=9823 GN=ABI3BP PE=1 SV=2 CANONICAL=A0A5G2QWN3-1" }, "locus": { "chromosome": "13", "start_pos": 158289650, "end_pos": 158013822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040507.2", "url": "https://www.ensembl.org/id/ENSSSCT00000040507.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038182.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038182.2" } ] } }, { "isoform_ac": "A0A287AQF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3/entry#A0A287AQF9-1", "sequence": { "sequence": "MFDISNALKTELAKNETLALPAESKTPEVEKIPAQPITATPESVPRTTKPTASSALDISETTLASSEKPWIVPTSKTSEDSKILPPQTAAYDVFSSPTTSDEPEIAEPHTATSDPFLDSLPRKTSRTLEQPRATLAPSETPFVPPELEIFTSPEMQPTTSAPLQTTSIPSTPKRRLRPKIPRTKPERTTRPGIITSKISKSPEPTWTTLAPSKTPFISLKPKIPLSPEVTHTKPAPEPETPPPSPPPIVLEPGTLGTKPSTTLAPPKTKRPGRRPRPRPKTTPSPDVPKSKPALEPATVQPEPLGPTVDSKPPKQLLPKPQTTAKPDMPPPKSVLEPVTSEPEEPSTTIVPDTDIEPVTLRTEALPTTLAPKTSQRTRTRRPRPRPKPKTTPSPETPQAKLDFEPVTPGTSLAPTATTTTTTTKRPRRPRPKLKTTPHPEVPQTKLVPATTPEPVTLRTEAPGTTIAPKVPQRTRHPRPKPKTTPSPEAPHTEPVPATDLEPVTPIKEAPVPVTDLEPVTFPTEISGTTLATKASQRPRRPRPRPKTTPSPQVPHTKPVPATALEPVTLKPEARGTTLVPTAVFEPVTLRTEAWVMTRAPKTSKRTRRPCPKPKTTPTPEAPRFKPVSTTDLVPGTEAPEIMAPIELQTLTLKPVTSPSLDMTQSQPAPKQTPRTPPKPKTSPRPRIPQTQPVPKVFQRVTPKPKTSPSPEVSYTPSVPRDVFLPHKPDPEVSQSEPVLQPVTFRIDLPESTIAPLETRGSPFIPMISPSSSQEELQTTLETDQSTQELFTTKLPRTTELAKTTQAPHRLFTTPVRPRTPDKPHVRPVLNKTTTRPSRPKPSGMPRGNGIGTGIKQTPLPSGPGRNVSLDSTHSTKKPAMIPGTRRPPLPPRPTPPRRKPLPPNNVTGKPGSAGIISSGRVTSPPLRATLRPTEAPLERIETDKKQPTAPASGEDLGNMTDFSSSPTRETDPLGKPRFKGPHVRYIQKPENRPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWDKPLNDTVTEYEVISRENGSFSGKNKSIQTTNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLSSDQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW", "length": 1255, "header": "tr|A0A287AQF9-1|A0A5G2QWN3_PIG Computationally mapped isoform of ABI family member 3 binding protein OS=Sus scrofa OX=9823 GN=ABI3BP PE=1 SV=2 CANONICAL=A0A5G2QWN3-1" }, "locus": { "chromosome": "13", "start_pos": 158289650, "end_pos": 158148924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057677.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057677.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046114.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046114.2" } ] } }, { "isoform_ac": "A0A5G2QEI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3/entry#A0A5G2QEI5-1", "sequence": { "sequence": "MLSSLGCLLLCGSIALALGNAQKLPKGKKPNLKVHINTTSDSIFLKFLRPHPNVKLEGFLLGYGSNLSPNQYFPLPAEGKYTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPQHDWTLPSQCPNDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPDTVYEFGVKDNVEGGIWSKIFNHKTIVGSKGKVNGKIQSTYDQVHTVPSYVPRKVIPVTIIKQVIQNVTHKASAKSPDRTPYGGTILVHLVIPGLNETTVKLPTSIMFDISNALKTELAKNETLALPAESKTPEVEKIPAQPITASSEKPWIVPTSKTSEDSKILPPQTATSDPFLDSLPRKTSRTLEQPRATLAPSETPFVPPELEIFTSPEMQPTTSAPLQTTSIPSTPKRRLRPKIPRTKPERTTRPGIITSKISKSPEPTWTTLAPSKTPFISLKPKIPLSPEVTHTKPAPEPETPPPSPPPIVLEPGTLGTKPSTTLAPPKTKRPGRRPRPRPKTTPSPDVPKSKPALEPATVQPEPLGPTVDSKPPKQLLPKPQTTAKPDMPPPKSVLEPVTSEPEEPSTTIVPDTDIEPVTLRTEALPTTLAPKTSQRTRTRRPRPRPKPKTTPSPETPQAKLDFEPVTPGTSLAPTATTTTTTTKRPRRPRPKLKTTPHPEVPQTKLVPATTPEPVTLRTEAPGTTIAPKVPQRTRHPRPKPKTTPSPEAPHTEPVPATDLEPVTPIKEAPVPVTDLEPVTFPTEISGTTLATKASQRPRRPRPRPKTTPSPQVPHTKPVPATALEPVTLKPEARGTTLVPTAVFEPVTLRTEAWVMTRAPKTSKRTRRPCPKPKTTPTPEAPRFKPVSTTDLVPGTEAPEIMVSEVVESVTFSTESSKEAIVPTETDYPTAKVPLRPEEPKTEVVESITYVSEPPETMLVTIETSPLPSQTIILPSPDEPQTEPAPKQTPRTPPKPKTSPRPRIPQTQPVPKVFQRVTPKPKTSPSPEVSYTPSVPRDVFLPHKPDPEVSQSEPVLQPVTFRIDLPESTIAPLETRGSPFIPMISPSSSQEELQTTLETDQSTQELFTTKLPRTTELAKTTQAPHRLFTTPVRPRTPDKPHVRPVLNKTTTRPSRPKPSGMPRGNGIGTGIKQTPLPSGPGRNVSLDSTHSTKKPAMIPGTRRPPLPPRPTPPRRKPLPPNNVTGKPGSAGIISSGRVTSPPLRATLRPTEAPLERIETDKKQPTAPASGEDLGNMTDFSSSPTRETDPLGKPRFKGPHVRYIQKPENRPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWDKPLNDTVTEYEVISRENGSFSGKNKSIQTTNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLSSDQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW", "length": 1557, "header": "tr|A0A5G2QEI5-1|A0A5G2QWN3_PIG Computationally mapped isoform of ABI family member 3 binding protein OS=Sus scrofa OX=9823 GN=ABI3BP PE=1 SV=1 CANONICAL=A0A5G2QWN3-1" }, "locus": { "chromosome": "13", "start_pos": 158289650, "end_pos": 158013822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074528.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074528.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060446.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060446.1" } ] } }, { "isoform_ac": "A0A5G2QHH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3/entry#A0A5G2QHH4-1", "sequence": { "sequence": "MLSSLGCLLLCGSIALALGNAQKLPKGKKPNLKVHINTTSDSIFLKFLRPHPNVKLEGFLLGYGSNLSPNQYFPLPAEGKYTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPQHDWTLPSQCPNDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPDTVYEFGVKDNVEGGIWSKIFNHKTIVGSKGKVNGKIQSTYDQVHTVPSYVPRKVIPVTIIKQVIQNVTHKASAKSPDRTPYGGTILVHLVIPGLNETTVKLPTSIMFDISNALKTELAKNETLALPAESKTPEVEKIPAQPITATPESVPRTTKPTASSALDISETTLASSEKPWIVPTSKTSEDSKILPPQTAAYDVFSSPTTSDEPEIAEPHTATSDPFLDSLPRKTSRTLEQPRATLAPSETPFVPPELEIFTSPEMQPTTSAPLQTTSIPSTPKRRLRPKIPRTKPERTTRPGIITSKISKSPEPTWTTLAPSKTPFISLKPKIPLSPEVTHTKPAPEPETPPPSPPPIVLEPGTLGTKPSTTLAPPKTKRPGRRPRPRPKTTPSPDVPKSKPALEPATVQPEPLGPTVDSKPPKQLLPKPQTTAKPDMPPPKSVLEPVTSEPEEPSTTIVPDTDIEPVTLRTEALPTTLAPKTSQRTRTRRPRPRPKPKTTPSPETPQAKLDFEPVTPGTSLVPATTPEPVTLRTEAPGTTIAPKVPQRTRHPRPKPKTTPSPEAPHTEPVPATDLEPVTPIKEAPVPVTDLEPVTFPTEISGTTLATKASQRPRRPRPRPKTTPSPQVPHTKPVPATALEPVTLKPEARGTTLVPTAVFEPVTLRTEAWVMTRAPKTSKRTRRPCPKPKTTPTPEAPRFKPVSTTDLVPGTEAPEIMALPTVLEPVIFRTKTPETTLVPAMSFEPVTYSSKAPETTLAPIELQTLTLKPVTSPSLDMTQSQPVSEVVESVTFSTESSKEAIVPTETDYPTAKVPLRPEEPKTEVVESITYVSEPPETMLVTIETSPLPSQTIILPSPDEPQTEPAPKQTPRTPPKPKTSPRPRIPQTQPVPKVFQRVTPKPKTSPSPEVSYTPSVPRDVFLPHKPDPEVSQSEPVLQPVTFRIDLPESTIAPLETRGSPFIPMISPSSSQEELQTTLETDQSTQELFTTKLPRTTELAKTTQAPHRLFTTPVRPRTPDKPHVRPVLNKTTTRPSRPKPSGMPRGNGIGTGIKQTPLPSGPGRNVSLDSTHSTKKPAMIPGTRRPPLPPRPTPPRRKPLPPNNVTGKPGSAGIISSGRVTSPPLRATLRPTEAPLERIETDKKQPTAPASGEDLGNMTDFSSSPTRETDPLGKPRFKGPHVRYIQKPENRPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWDKPLNDTVTEYEVISRENGSFSGKNKSIQTTNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLSSDQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW", "length": 1635, "header": "tr|A0A5G2QHH4-1|A0A5G2QWN3_PIG Computationally mapped isoform of ABI family member 3 binding protein OS=Sus scrofa OX=9823 GN=ABI3BP PE=1 SV=1 CANONICAL=A0A5G2QWN3-1" }, "locus": { "chromosome": "13", "start_pos": 158289650, "end_pos": 158013822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086162.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086162.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063804.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063804.1" } ] } }, { "isoform_ac": "A0A5G2QIF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3/entry#A0A5G2QIF2-1", "sequence": { "sequence": "MLSSLGCLLLCGSIALALGNAQKLPKGKKPNLKVHINTTSDSIFLKFLRPHPNVKLEGFLLGYGSNLSPNQYFPLPAEGKYTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPQHDWTLPSQCPNDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPDTVYEFGVKDNVEGGIWSKIFNHKTIVGSKGKVNGKIQSTYDQVHTVPSYVPRKVIPVTIIKQVIQNVTHKASAKSPDRTPYGGTILVHLVIPGLNETTVKLPTSIMFDISNALKTELAKNETLALPAESKTPEVEKIPAQPITATPESVPRTTKPTASSALDISETTLASSEKPWIVPTSKTSEDSKILPPQTAAYDVFSSPTTSDEPEIAEPHTATSDPFLDSLPRKTSRTLEQPRATLAPSETPFVPPELEIFTSPEMQPTTSAPLQTTSIPSTPKRRLRPKIPRTKPERTTRPGIITSKISKSPEPTWTTLAPSKTPFISLKPKIPLSPEVTHTKPAPEPETPPPSPPPIVLEPGTLGTKPSTTLAPPKTKRPGRRPRPRPKTTPSPDVPKSKPALEPATVQPEPLGPTVDSKPPKQLLPKPQTTAKPDMPPPKSVLEPVTSEPEEPSTTIVPDTDIEPVTLRTEALPTTLAPKTSQRTRTRRPRPRPKPKTTPSPETPQAKLDFEPVTPGTSLAPTATTTTTTTKRPRRPRPKLKTTPHPEVPQTKLVPATTPEPVTLRTEAPGTTIAPKVPQRTRHPRPKPKTTPSPEAPHTEPVPATDLEPVTPIKEAPVPVTDLEPVTFPTEISGTTLATKASQRPRRPRPRPKTTPSPQVPHTKPVPATALEPVTLKPEARGTTLVPTAVFEPVTLRTEAWVMTRAPKTSKRTRRPCPKPKTTPTPEAPRFKPVSTTDLVPGTEAPEIMALPTVLEPVIFRTKTPETTLAPIELQTLTLKPVTSPSLDMTQSQPVSEVVESVTFSTESSKEAIVPTETDYPTAKVPLRPEEPKTEVVESITYVSEPPETMLVTIETSPLPSQTIILPSPDEPQTEPAPKQTPRTPPKPKTSPRPRIPQTQPVPKVFQRVTPKPKTSPSPEVSYTPSVPRDVFLPHKPDPEVSQSEPVLQPVTFRIDLPESTIAPLETRGSPFIPMISPSSSQEELQTTLETDQSTQELFTTKLPRTTELAKTTQAPHRLFTTPVRPRTPDKPHVRPVLNKTTTRPSRPKPSGMPRGNGIGTGIKQTPLPSGPGRNVSLDSTHSTKKPAMIPGTRRPPLPPRPTPPRRKPLPPNNVTGKPGSAGIISSGRVTSPPLRATLRPTEAPLERIETDKKQPTAPASGEDLGNMTDFSSSPTRETDPLGKPRFKGPHVRYIQKPENRPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWDKPLNDTVTEYEVISRENGSFSGKNKSIQTTNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLSSDQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW", "length": 1649, "header": "tr|A0A5G2QIF2-1|A0A5G2QWN3_PIG Computationally mapped isoform of ABI family member 3 binding protein OS=Sus scrofa OX=9823 GN=ABI3BP PE=1 SV=1 CANONICAL=A0A5G2QWN3-1" }, "locus": { "chromosome": "13", "start_pos": 158289650, "end_pos": 158013822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084217.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084217.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064205.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064205.1" } ] } }, { "isoform_ac": "A0A5G2QUX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3/entry#A0A5G2QUX0-1", "sequence": { "sequence": "MLSSLGCLLLCGSIALALGNAQKLPKGKKPNLKVHINTTSDSIFLKFLRPHPNVKLEGFLLGYGSNLSPNQYFPLPAEGKYTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPQHDWTLPSQCPNDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPDTVYEFGVKDNVEGGIWSKIFNHKTIVGSKGKVNGKIQSTYDQVHTVPSYVPRKVIPVTIIKQVIQNVTHKASAKSPDRTPYGGTILVHLVIPGLNETTVKLPTSIMFDISNALKTELAKNETLALPAESKTPEVEKIPAQPITATPESVPRTTKPTASSALDISETTLASSEKPWIVPTSKTSEDSKILPPQTAAYDVFSSPTTSDEPEIAEPHTATSDPFLDSLPRKTSRTLEQPRATLAPSETPFVPPELEIFTSPEMQPTTSAPLQTTSIPSTPKRRLRPKIPRTKPERTTRPGIITSKISKSPEPTWTTLAPSKTPFISLKPKIPLSPEVTHTKPAPEPETPPPSPPPIVLEPGTLGTKPSTTLAPPKTKRPGRRPRPRPKTTPSPDVPKSKPALEPATVQPEPLGPTVDSKPPKQLLPKPQTTAKPDMPPPKSVLEPVTSEPEEPSTTIVPDTDIEPVTLRTEALPTTLAPKTSQRTRTRRPRPRPKPKTTPSPETPQAKLDFEPVTPGTSLAPTATTTTTTTKRPRRPRPKLKTTPHPEVPQTKLVPATTPEPVTLRTEAPGTTIAPKVPQRTRHPRPKPKTTPSPEAPHTEPVPATDLEPVTPIKEAPVPVTDLEPVTFPTEISGTTLATKASQRPRRPRPRPKTTPSPQVPHTKPVPATALEPVTLKPEARGTTLVPTAVFEPVTLRTEAWVMTRAPKTSKRTRRPCPKPKTTPTPEAPRFKPVSTTDLVPGTEAPEIMALPTVLEPVIFRTKTPETTLVPAMSFEPVTYSSKAPETTLAPIELQTLTLKPVTSPSLDMTQSQPVSEVVESVTFSTESSKEAIVPTETDYPTAKVPLRPEEPKTEVVESITYVSEPPETMLAPKQTPRTPPKPKTSPRPRIPQTQPVPKVFQRVTPKPKTSPSPEVSYTPSVPRDVFLPHKPDPEVSQSEPVLQPVTFRIDLPESTIAPLETRGSPFIPMISPSSSQEELQTTLETDQSTQELFTTKLPRTTELAKTTQAPHRLFTTPVRPRTPDKPHVRPVLNKTTTRPSRPKPSGMPRGNGIGTGIKQTPLPSGPGRNVSLDSTHSTKKPAMIPGTRRPPLPPRPTPPRRKPLPPNNVTGKPGSAGIISSGRVTSPPLRATLRPTEAPLERIETDKKQPTAPASGEDLGNMTDFSSSPTRETDPLGKPRFKGPHVRYIQKPENRPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWDKPLNDTVTEYEVISRENGSFSGKNKSIQTTNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLSSDQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW", "length": 1644, "header": "tr|A0A5G2QUX0-1|A0A5G2QWN3_PIG Computationally mapped isoform of ABI family member 3 binding protein OS=Sus scrofa OX=9823 GN=ABI3BP PE=1 SV=1 CANONICAL=A0A5G2QWN3-1" }, "locus": { "chromosome": "13", "start_pos": 158289650, "end_pos": 158013822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078902.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078902.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061966.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061966.1" } ] } }, { "isoform_ac": "A0A5G2QWN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3/entry#A0A5G2QWN3-1", "sequence": { "sequence": "MLSSLGCLLLCGSIALALGNAQKLPKGKKPNLKVHINTTSDSIFLKFLRPHPNVKLEGFLLGYGSNLSPNQYFPLPAEGKYTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPQHDWTLPSQCPNDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPDTVYEFGVKDNVEGGIWSKIFNHKTIVGSKGKVNGKIQSTYDQVHTVPSYVPRKVIPVTIIKQVIQNVTHKASAKSPDRTPYGGTILVHLVIPGLNETTVKLPTSIMFDISNALKTELAKNETLALPAESKTPEVEKIPAQPITATPESVPRTTKPTASSALDISETTLAPKSLPEFPQAKTPFPFEKSWGTLASSEKPWIVPTSKTSEDSKILPPQTATSDPFLDSLPRKTSRTLEQPRATLAPSETPFVPPELEIFTSPEMQPTTSAPLQTTSIPSTPKRRLRPKIPRTKPERTTRPGIITSKISKSPEPTWTTLAPSKTPFISLKPKIPLSPEVTHTKPAPEPETPPPSPPPIVLEPGTLGTKPSTTLAPPKTKRPGRRPRPRPKTTPSPDVPKSKPALEPATVQPEPLGPTVDSKPPKQLLPKPQTTAKPDMPPPKSVLEPVTSEPEEPSTTIVPDTDIEPVTLRTEALPTTLAPKTSQRTRTRRPRPRPKPKTTPSPETPQAKLDFEPVTPGTSLATTTTTTTKRPRRPRPKLKTTPHPEVPQTKLVPATTPEPVTLRTEAPGTTIAPKVPQRTRHPRPKPKTTPSPEAPHTEPVPATDLEPVTPIKEAPVPVTDLEPVTFPTEISGTTLATKASQRPRRPRPRPKTTPSPQVPHTKPVPATALEPVTLKPEARGTTLVPTAVFEPVTLRTEAWVMTRAPKTSKRTRRPCPKPKTTPTPEAPRFKPVSTTDLVPGTEAPEIMALPTVLEPVIFRTKTPETTLVPAMSFEPVTYSSKAPETTLAPIELQTLTLKPVTSPSLDMTQSQPVSEVVESVTFSTESSKEAIVPTETDYPTAKVPLRPEEPKTEVVESITYVSEPPETMLVTIETSPLPSQTIILPSPDEPQTEPAPKQTPRTPPKPKTSPRPRIPQTQPVPKVFQRVTPKPKTSPSPEVSYTPSVPRDVFLPHKPDPEVSQSEPVLQPVTFRIDLPESTIAPLETRGSPFIPMISPSSSQEELQTTLETDQSTQELFTTKLPRTTELAKTTQAPHRLFTTPVRPRTPDKPHVRPVLNKTTTRPSRPKPSGMPRGNGIGTGIKQTPLPSGPGRNVSLDSTHSTKKPAMIPGTRRPPLPPRPTPPRRKPLPPNNVTGKPGSAGIISSGRVTSPPLRATLRPTEAPLERIETDKKQPTAPASGEDLGNMTDFSSSPTRETDPLGKPRFKGPHVRYIQKPENRPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWDKPLNDTVTEYEVISRENGSFSGKNKSIQTTNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLSSDQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW", "length": 1668, "header": "tr|A0A5G2QWN3-1|A0A5G2QWN3_PIG Isoform 1 of ABI family member 3 binding protein OS=Sus scrofa OX=9823 GN=ABI3BP PE=1 SV=1 CANONICAL=A0A5G2QWN3-1" }, "locus": { "chromosome": "13", "start_pos": 158289650, "end_pos": 158013822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070803.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070803.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062589.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062589.1" } ] } }, { "isoform_ac": "A0A5G2RB21-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3/entry#A0A5G2RB21-1", "sequence": { "sequence": "MLSSLGCLLLCGSIALALGNAQKLPKGKKPNLKVHINTTSDSIFLKFLRPHPNVKLEGFLLGYGSNLSPNQYFPLPAEGKYTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPQHDWTLPSQCPNDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPDTVYEFGVKDNVEGGIWSKIFNHKTIVGSKGKVNGKIQSTYDQVHTVPSYVPRKVIPVTIIKQVIQNVTHKASAKSPDRTPYGGTILVHLVIPGLNETTVKLPTSIMFDISNALKTELAKNETLALPAESKTPEVEKIPAQPITATPESVPRTTKPTASSALDISETTLAPKSLPEFPQAKTPFPFEKSWGTLASSEKPWIVPTSKTSEDSKILPPQTAAYDVFSSPTTSDEPEIAEPHTATSDPFLDSLPRKTSRTLEQPRATLAPSETPFVPPELEIFTSPEMQPTTSAPLQTTSIPSTPKRRLRPKIPRTKPERTTRPGIITSKISKSPEPTWTTLAPSKTPFISLKPKIPLSPEVTHTKPVLEPGTLGTKPSTTLAPPKTKRPGRRPRPRPKTTPSPDVPKSKPALEPATVQPEPLGPTVDSKPPKQLLPKPQTTAKPDMPPPKSVLEPVTSEPEEPSTTIVPDTDIEPVTLRTEALPTTLAPKTSQRTRTRRPRPRPKPKTTPSPETPQAKLDFEPVTPGTSLATTTTTTTKRPRRPRPKLKTTPHPEVPQTKLVPATTPEPVTLRTEAPGTTIAPKVPQRTRHPRPKPKTTPSPEAPHTEPVPATDLEPVTPIKEAPVPVTDLEPVTFPTEISGTTLATKASQRPRRPRPRPKTTPSPQVPHTKPVPATALEPVTLKPEARGTTLVPTAVFEPVTLRTEAWVMTRAPKTSKRTRRPCPKPKTTPTPEAPRFKPVSTTDLVPGTEAPEIMALPTVLEPVIFRTKTPETTLAPIELQTLTLKPVTSPSLDMTQSQPVSEVVESVTFSTESSKEAIVPTETDYPTAKVPLRPEEPKTEVVESITYVSEPPETMLVTIETSPLPSQTIILPSPDEPQTEPAPKQTPRTPPKPKTSPRPRIPQTQPVPKVFQRVTPKPKTSPSPEVSYTPSVPRDVFLPHKPDPEVSQSEPVLQPVTFRIDLPESTIAPLETRGSPFIPMISPSSSQEELQTTLETDQSTQELFTTKLPRTTELAKTTQAPHRLFTTPVRPRTPDKPHVRPVLNKTTTRPSRPKPSGMPRGNGIGTGIKQTPLPSGPGRNVSLDSTHSTKKPAMIPGTRRPPLPPRPTPPRRKPLPPNNVTGKPGSAGIISSGRVTSPPLRATLRPTEAPLERIETDKKQPTAPASGEDLGNMTDFSSSPTRETDPLGKPRFKGPHVRYIQKPENRPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWDKPLNDTVTEYEVISRENGSFSGKNKSIQTTNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLSSDQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW", "length": 1656, "header": "tr|A0A5G2RB21-1|A0A5G2QWN3_PIG Computationally mapped isoform of ABI family member 3 binding protein OS=Sus scrofa OX=9823 GN=ABI3BP PE=1 SV=1 CANONICAL=A0A5G2QWN3-1" }, "locus": { "chromosome": "13", "start_pos": 158289650, "end_pos": 158013822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084609.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084609.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071345.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071345.1" } ] } }, { "isoform_ac": "F1SL03-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3/entry#F1SL03-1", "sequence": { "sequence": "MLSSLGCLLLCGSIALALGNAQKLPKGKKPNLKVHINTTSDSIFLKFLRPHPNVKLEGFLLGYGSNLSPNQYFPLPAEGKYTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPQHDWTLPSQCPNDRFYTIRYREKDKEKKWIFQLCPATETIVENLKPDTVYEFGVKDNVEGGIWSKIFNHKTIVGSKGKVNGKIQSTYDQVHTVPSYVPRKVIPVTIIKQVIQNVTHKASAKSPDRTPYGGTILVHLVIPGLNETTVKLPTSIMFDISNALKTELAKNETLALPAESKTPEVEKIPAQPITASSEKPWIVPTSKTSEDSKILPPQTAAYDVFSSPTTSDEPEIAEPHTATSDPFLDSLPRKTSRTLEQPRATLAPSETPFVPPELEIFTSPEMQPTTSAPLQTTSIPSTPKRRLRPKIPRTKPERTTRPGIITSKISKSPEPTWTTLAPSKTPFISLKPKIPLSPEVTHTKPAPEPETPPPSPPPIVLEPGTLGTKPSTTLAPPKTKRPGRRPRPRPKTTPSPDVPKSKPALEPATVQPEPLGPTVVLEPVTSEPEEPSTTIVPDTDIEPVTLRTEALPTTLAPKTSQRTRTRRPRPRPKPKTTPSPETPQAKLDFEPVTPGTSLAPTATTTTTTTKRPRRPRPKLKTTPHPEVPQTKLVPATTPEPVTLRTEAPGTTIAPKVPQRTRHPRPKPKTTPSPEAPHTEPVPATDLEPVTPIKEAPVPVTDLEPVTFPTEISGTTLATKASQRPRRPRPRPKTTPSPQVPHTKPVPATALEPVTLKPEARGTTLAPKTSKRTRRPCPKPKTTPTPEAPRFKPAPKQTPRTPPKPKTSPRPRIPQTQPVPKVFQRVTPKPKTSPSPEVSYTPSVPRDVFLPHKPDPEVSQSEPVLQPVTFRIDLPESTIAPLETRGSPFIPMISPSSSQEELQTTLETDQSTQELFTTKLPRTTELAKTTQAPHRLFTTPVRPRTPDKPHVRPVLNKTTTRPSRPKPSGMPRGNGIGTGIKQTPLPSGPGRNVSLDSTHSTKKPAMIPGTRRPPLPPRPTPPRRKPLPPNNVTGKPGSAGIISSGRVTSPPLRATLRPTEAPLERIETDKKQPTAPASGEDLGNMTDFSSSPTRETDPLGKPRFKGPHVRYIQKPENRPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWDKPLNDTVTEYEVISRENGSFSGKNKSIQTTNQTFSTVENLKPDTSYEFQVKPKNPLGEGPASNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLSSDQLPTKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW", "length": 1436, "header": "tr|F1SL03-1|A0A5G2QWN3_PIG Computationally mapped isoform of ABI family member 3 binding protein OS=Sus scrofa OX=9823 GN=ABI3BP PE=1 SV=4 CANONICAL=A0A5G2QWN3-1" }, "locus": { "chromosome": "13", "start_pos": 158289650, "end_pos": 158013822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013085.4", "url": "https://www.ensembl.org/id/ENSSSCT00000013085.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012740.4", "url": "https://www.ensembl.org/id/ENSSSCP00000012740.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1307, "start_aa": "Thr", "end_pos": 1307, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1307", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 601, "start_aa": "Thr", "end_pos": 601, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr601", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QEI5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEI5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of connective tissue replacement involved in inflammatory response wound healing", "id": "GO:1904597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904597", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3" } ], "pmid": "" }, { "name": "positive regulation of cardiocyte differentiation", "id": "GO:1905209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905209", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1243, "end_pos": 1245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1279, "end_pos": 1281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1318, "end_pos": 1320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1371, "end_pos": 1373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1425, "end_pos": 1427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1436, "end_pos": 1438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1458, "end_pos": 1460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1471, "end_pos": 1473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1478, "end_pos": 1480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1485, "end_pos": 1487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN3" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 214, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 601, 1307 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1243, "end_pos": 1245 }, { "start_pos": 1279, "end_pos": 1281 }, { "start_pos": 1318, "end_pos": 1320 }, { "start_pos": 1371, "end_pos": 1373 }, { "start_pos": 1425, "end_pos": 1427 }, { "start_pos": 1436, "end_pos": 1438 }, { "start_pos": 1458, "end_pos": 1460 }, { "start_pos": 1471, "end_pos": 1473 }, { "start_pos": 1478, "end_pos": 1480 }, { "start_pos": 1485, "end_pos": 1487 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3A1-1", "uniprot_ac": "A0A5G2R3A1", "uniprot_id": "A0A5G2R3A1_PIG", "mass": { "chemical_mass": 263438.0, "monoisotopic_mass": 263438.0 }, "refseq": {}, "gene_names": [ { "name": "AHCTF1", "type": "recommended", "evidence": [ { "id": "A0A5G2R3A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" } ] } ], "protein_names": [ { "name": "AT-hook containing transcription factor 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R3A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AHCTF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1", "locus": { "chromosome": "10", "start_pos": 15132326, "end_pos": 15042275, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010863", "url": "https://www.ensembl.org/id/ENSSSCG00000010863" } ] } } ], "crossref": [ { "id": "ENSSSCG00000010863", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010863", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR025151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KWNHDCL", "url": "https://omabrowser.org/oma/group/KWNHDCL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21583", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21583", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21583:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21583:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13934", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13934", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68877", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9615933", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9615933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A0A3", "url": "https://www.uniprot.org/uniprotkb/A0A287A0A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A0A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3H9", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S8P4", "url": "https://www.uniprot.org/uniprotkb/F1S8P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S8P4-1", "url": "https://www.uniprot.org/uniprotkb/F1S8P4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSLAGAARSRAPSVGYITSFSAERRHMATERRLGVYTPLLARLQPCPHVSQAVLDCDPFSLLPSGAVETLAGLPLAEPAGTLSLSYVGVCSTCSRAWLGESMRDLTAQVTSDLLQFPEVTIQALGEDEITLESVLRGKFAAGRNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPIVLAVKEFSWQKRTGLLIGLEEFEGSVLCLYDLGLSRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSGSQNEVEASDLEVITGIPAEVPHIRENVMREGRHLCFQLVSPSGIAVSTLSYINRTNQLAVGFSDGYLALWNMKSMKREYYTQLEGGRVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLTGGGMFPVRGQTGNTKLLGCQSIEKFRSHGDREEGMNEALSPDTSVSVFTWQVNIYGQGKPSIYLGLFDINRWYHAQMPDSLRSGEYLHNCSYFALWSLDSVVSKTSPHYVLDVLVHERSLSRGVPPSYPPPEQFFNPSTYNFDATCLLNSGVVHITCTGFQKETLTFLKKSGPSLNEVIPDGYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGCIRRWITEEQPNSAANLRFVLEWTWNKVVFTKGEFDRLCAPLFDGSCRFIDPQTIQSIQQCSLLLSNLNTVLSCFATEAQEITERGVMDLSNKYTVSQLICQYAQVVLWFSHSGLLPEGLDDAVQLSRLCYNYPVIQNYYTSRRQKCERLSRGKWNPDCLMIDGMVSQLGDRVEKLWKRDEGGTGKYPPTSLHALLDIYLLEDVTEASKHSITIYLLLDIMYSFPNKTDTSIESFPTAFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPVSWQHSKIIQAFMSQGEPRQALRYIQTMRPTVSTDSDVTLHLTVLLFNRCMVEAWDLVRQHSSRLNIEELLKHTYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASIQNHEFLLVHHLQRANYIPALKLNQTLKINLMNDRDPRLRERSVARNSILDQYGKILPRVQRKLAIERAKPYRLSASSVLREVSRPKPLSAVPKQAVTGTVFTRSTFINNVLSKIGEVWASSEPKNSLSVYNSPKIEAPSPVVYSLPDLELPEAFVGTPISKASQKISRLLDLVVQPVPQPSQCLGFIQHIPPRSPLYLVSSSLSLSSQLKESRQNASRASELHLLETPLVVKKAKTLAMSVTSSGFAEFTPQSILRSGLRTTPLASPSLSPGRSLTPPLRLKETRISFMEEGLTTEWAAGAADDSKTKVFITEPFHKCGVPAETGWQKNKDKTTSFSMSSPEKDHQEVDVQSQDTTSQGLEKLDISVEHSNASTRSDQTTLEYQDAPLPEDLEDIFMASMPPSSSTELITNLTGQSEKDSDKDVFESEVTPPDLEKQMGTLEDAETRDLLVAEGALSELNHLSPSQGVEASCVSSIHEGSILTPESMVPVLDKGLVSIETCTSTIRTGNNKSVADVLGDNGSSGLLISESPAISEHRLDQEVALNVKEDHEIEVDVLKARVDLPEEKPPISDDPPDTQEIHVVEHEKVEVQDSGQEARNLSFNELYPSGTLKLQYNFDTIEKQFCDLPDSKDSAECDIAEVDRELFVAQSNFTLILEGEEGEIETGDSAASNVLAKAANAATEEKHTCSRENDSHRHVANLPSVLTSDQESQKVETLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHDNIPLISQKVMCSTKLAKTPFKTVQETSAVTINVSQINDMISSRTRKKRRVQDMSVKSAHQEESADVATPEMLGLSIMKKTRKTKEISGAFESASSDDKGISQNQQTPQNSVTPRRGRRKKEINQDTSEDINSVEQELEATPGRELRRVKSSQLLESVTEESSFRKDVKLSSVTKRTPKRIKKSVENQESVEVINDLKVSKIASPSRSTRKLRSACLETSESTAGESTEQQLPLQRNRRVRKREGSASDVVEDSKFDSSQRKPPAEFDTPATPRKRGRPRKTNPSEDVESKAVKGARSPETREGLNIQRRSTRNTPAKSGNTEVGKLALETSVFVPSEELATPVSSKKKPTKRTENQSQKRPLRSISEKCIDEEMTHKEVDDQEEKLLATVALTKSSRGTRTRSSKAVLLPDLSEPKNESLFSPPVSKIPRKEKAKKIEAPAQLKELVSDLSSQFVFSPPALRTRQKNLTNTSKLIDKLEDDAPSVETVEKQQVKRARTTKTRQASKNTEKESWSPPPVEVKLISPLASPVDGVKSRPRRAAEVTGKTLGRSRKKVSSFPKQVLRRKML", "length": 2374, "header": "tr|A0A5G2R3A1-1|A0A5G2R3A1_PIG Isoform 1 of AT-hook containing transcription factor 1 OS=Sus scrofa OX=9823 GN=AHCTF1 PE=1 SV=2 CANONICAL=A0A5G2R3A1-1" }, "isoforms": [ { "isoform_ac": "A0A287A0A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1/entry#A0A287A0A3-1", "sequence": { "sequence": "MRDLTAQVTSDLLQFPEVTIQALGEDEITLESVLRGKFAAGRNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPIVLAVKEFSWQKRTGLLIGLEEFEGSVLCLYDLGLSRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSGSQNEVEASDLEVITGIPAEVPHIRENVMREGRHLCFQLVSPSGIAVSTLSYINRTNQLAVGFSDGYLALWNMKSMKREYYTQLEGGRVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLTGGGMFPVRGQTGNTKLLGCQSIEKFRSHGDREEGMNEALSPDTSVSVFTWQVNIYGQGKPSIYLGLFDINRWYHAQMPDSLRSGEYLHNCSYFALWSLDSVVSKTSPHYVLDVLVHERSLSRGVPPSYPPPEQFFNPSTYNFDATCLLNSGVVHITCTGFQKETLTFLKKSGPSLNEVIPDGYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGCIRRWITEEQPNSAANLRFVLEWTWNKVVFTKGEFDRLCAPLFDGSCRFIDPQTIQSIQQCSLLLSNLNTVLSCFATEAQEITERGVMDLSNKYTVSQLICQYAQVVLWFSHSGLLPEGLDDAVQLSRLCYNYPVIQNYYTSRRQKCERLSRGKWNPDCLMIDGMVSQLGDRVEKLWKRDEGGTGKYPPTSLHALLDIYLLEDVTEASKHSITIYLLLDIMYSFPNKTDTSIESFPTAFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPVSWQHSKIIQAFMSQGEPRQALRYIQTMRPTVSTDSDVTLHLTVLLFNRCMVEAWDLVRQHSSRLNIEELLKHTYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASIQNHEFLLVHHLQRANYIPALKLNQTLKINLMNDRDPRLRERSVARNSILDQYGKILPRVQRKLAIERAKPYRLSASSVLREVSRPKPLSAVPKQAVTGTVFTRSTFINNVLSKIGEVWASSEPKNSLSVYNSPKIEAPSPVVYSLPDLELPEAFVGTPISKASQKISRLLDLVVQPVPQPSQCLGFIQHIPPRSPLYLVSSSLSLSSQLKESRQNASRASELHLLETPLVVKKAKTLAMSVTSSGFAEFTPQSILRSGLRTTPLASPSLSPGRSLTPPLRLKETRISFMEEGLTTEWAAGAADDSKTKVFITEPFHKCGVPAETGWQKNKDKTTSFSMSSPEKDHQEVDVQSQDTTSQGLEKLDISVEHSNASTRSDQTTLEYQDAPLPEDLEDIFMASMPPSSSTELITNLTGQSEKDSDKDVFESEVTPPDLEKQMEDAETRDLLVAEGALSELNHLSPSQGVEASCVSSIHEGSILTPESMVPVLDKGLVSIETCTSTIRTAVADVLGDNGSSGLLISESPAISEHRLDQEVALNVKEDHEIEVDVLKARVDLPEEKPPISDDPPDTQEIHVVEHEKVEVQDSGQEARNLSFNELYPSGTLKLQYNFDTIEKQFCDLPDSKDSAECDIAEVDRELFVAQSNFTLILEGEEGEIETGDSAASNVLAKAANAATEEKHTCSRENDSHRHVANLPSVLTSDQESQKVETLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHDNIPLISQKVMCSTKLAKTPFKTVQETSAVTINVSQINDMISSRTRKKRRVQDMSVKSAHQEESADVATPEMLGLSIMKKTRKTKEISGAFESASSDDKGISQNQQTPQNSVTPRRGRRKKEINQDTSEDINSVEQELEATPGRELRRVKSSQLLESVTEESSFRKDVKLSSVTKRTPKRIKKSVENQESVEVINDLKVSKIASPSRSTRKLRSACLETSESTAGESTEQQLPLQRNRRVRKREGSASDVVEDSKFDSSQRKPPAEFDTPATPRKRGRPRKTNPSEDVESKAVKGARSPETREGLNIQRRSTRNTPAKSGNTEVGKLALETSVFVPSEELATPVSSKKKPTKRTENQSQKRPLRSISEKCIDEEMTHKEVDDQEEKLLATVALTKSSRGTRTRSSKAVLLPDLSEPKNESLFSPPVSKIPRKEKAKKIEAPAQLKELVSDLSSQFVFSPPALRTRQKNLTNTSKLIDKLEDDAPSVETVEKQQVKRARTTKTRQASKNTEKESWSPPPVEVKLISPLASPVDGVKSRPRRAAEVTGKTLGRSRKKVSSFPKQVLRRKMLTTTIIQDPKNPEHTKTFIFDLAYWSHNGFQKDKDGVFISVDPSSKFAGQVSCFKTTLMDVGFCCCFFK", "length": 2333, "header": "tr|A0A287A0A3-1|A0A5G2R3A1_PIG Computationally mapped isoform of AT-hook containing transcription factor 1 OS=Sus scrofa OX=9823 GN=AHCTF1 PE=1 SV=1 CANONICAL=A0A5G2R3A1-1" }, "locus": { "chromosome": "10", "start_pos": 15132323, "end_pos": 15051113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047033.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047033.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037183.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037183.2" } ] } }, { "isoform_ac": "A0A287A3H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1/entry#A0A287A3H9-1", "sequence": { "sequence": "MRDLTAQVTSDLLQFPEVTIQALGEDEITLESVLRGKFAAGRNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPIVLAVKEFSWQKRTGLLIGLEEFEGSVLCLYDLGLSRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSGSQNEVEASDLEVITGIPAEVPHIRENVMREGRHLCFQLVSPSGIAVSTLSYINRTNQLAVGFSDGYLALWNMKSMKREYYTQLEGGRVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLTGGGMFPVRGQTGNTKLLGCQSIEKFRSHGDREEGMNEALSPDTSVSVFTWQVNIYGQGKPSIYLGLFDINRWYHAQMPDSLRSGEYLHNCSYFALWSLDSVVSKTSPHYVLDVLVHERSLSRGVPPSYPPPEQFFNPSTYNFDATCLLNSGVVHITCTGFQKETLTFLKKSGPSLNEVIPDGYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGCIRRWITEEQPNSAANLRFVLEWTWNKVVFTKGEFDRLCAPLFDGSCRFIDPQTIQSIQQCSLLLSNLNTVLSCFATEAQEITERGVMDLSNKYTVSQLICQYAQVVLWFSHSGLLPEGLDDAVQLSRLCYNYPVIQNYYTSRRQKCERLSRGKWNPDCLMIDGMVSQLGDRVEKLWKRDEGGTGKYPPTSLHALLDIYLLEDVTEASKHSITIYLLLDIMYSFPNKTDTSIESFPTAFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPVSWQHSKIIQAFMSQGEPRQALRYIQTMRPTVSTDSDVTLHLTVLLFNRCMVEAWDLVRQHSSRLNIEELLKHTYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASIQNHEFLLVHHLQRANYIPALKLNQTLKINLMNDRDPRLRERSVARNSILDQYGKILPRVQRKLAIERAKPYRLSASSVLREVSRPKPLSAVPKQAVTGTVFTRSTFINNVLSKIGEVWASSEPKNSLSVYNSPKIEAPSPVVYSLPDLELPEAFVGTPISKASQKISRLLDLVVQPVPQPSQCLGFIQHIPPRSPLYLVSSSLSLSSQLKESRQNASRASELHLLETPLVVKKAKTLAMSVTSSGFAEFTPQSILRSGLRTTPLASPSLSPGRSLTPPLRLKETRISFMEEGLTTEWAAGAADDSKTKVFITEPFHKCGVPAETGWQKNKDKTTSFSMSSPEKDHQEVDVQSQDTTSQGLEKLDISVEHSNASTRSDQTTLEYQDAPLPEDLEDIFMASMPPSSSTELITNLTGQSEKDSDKDVFESEVTPPDLEKQMAVADVLGDNGSSGLLISESPAISEHRLDQEVALNVKEDHEIEVDVLKARVDLPEEKPPISDDPPDTQEIHVVEHEKVEVQDSGQEARNLSFNELYPSGTLKLQYNFDTIEKQFCDLPDSKDSAECDIAEVDRELFVAQSNFTLILEGEEGEIETGDSAASNVLAKAANAATEEKHTCSRENDSHRHVANLPSVLTSDQESQKVETLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHDNIPLISQKVMCSTKLAKTPFKTVQETSAVTINVSQINDMISSRTRKKRRVQDMSVKSAHQEESADVATPEMLGLSIMKKTRKTKEISGAFESASSDDKGISQNQQTPQNSVTPRRGRRKKEINQDTSEDINSVEQELEATPGRELRRVKSSQLLESVTEESSFRKDVKLSSVTKRTPKRIKKSVENQESVEVINDLKVSKIASPSRSTRKLRSACLETSESTAGESTEQQLPLQRNRRVRKREGSASDVVEDSKFDSSQRKPPAEFDTPATPRKRGRPRKTNPSEDVESKAVKGARSPETREGLNIQRRSTRNTPAKSGNTEVGKLALETSVFVPSEELATPVSSKKKPTKRTENQSQKRPLRSISEKCIDEEMTHKEVDDQEEKLLATVALTKSSRGTRTRSSKAVLLPDLSEPKNESLFSPPVSKIPRKEKAKKIEAPAQLKELVSDLSSQFVFSPPALRTRQKNLTNTSKLIDKLEDDAPSVETVEKQQVKRARTTKTRQASKNTEKESWSPPPVEVKLISPLASPVDGVKSRPRRAAEVTGKTLGRSRKKVSSFPKQVLRRKML", "length": 2199, "header": "tr|A0A287A3H9-1|A0A5G2R3A1_PIG Computationally mapped isoform of AT-hook containing transcription factor 1 OS=Sus scrofa OX=9823 GN=AHCTF1 PE=1 SV=1 CANONICAL=A0A5G2R3A1-1" }, "locus": { "chromosome": "10", "start_pos": 15120342, "end_pos": 15051113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039756.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039756.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038524.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038524.1" } ] } }, { "isoform_ac": "A0A5G2R3A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1/entry#A0A5G2R3A1-1", "sequence": { "sequence": "MRSLAGAARSRAPSVGYITSFSAERRHMATERRLGVYTPLLARLQPCPHVSQAVLDCDPFSLLPSGAVETLAGLPLAEPAGTLSLSYVGVCSTCSRAWLGESMRDLTAQVTSDLLQFPEVTIQALGEDEITLESVLRGKFAAGRNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPIVLAVKEFSWQKRTGLLIGLEEFEGSVLCLYDLGLSRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSGSQNEVEASDLEVITGIPAEVPHIRENVMREGRHLCFQLVSPSGIAVSTLSYINRTNQLAVGFSDGYLALWNMKSMKREYYTQLEGGRVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLTGGGMFPVRGQTGNTKLLGCQSIEKFRSHGDREEGMNEALSPDTSVSVFTWQVNIYGQGKPSIYLGLFDINRWYHAQMPDSLRSGEYLHNCSYFALWSLDSVVSKTSPHYVLDVLVHERSLSRGVPPSYPPPEQFFNPSTYNFDATCLLNSGVVHITCTGFQKETLTFLKKSGPSLNEVIPDGYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGCIRRWITEEQPNSAANLRFVLEWTWNKVVFTKGEFDRLCAPLFDGSCRFIDPQTIQSIQQCSLLLSNLNTVLSCFATEAQEITERGVMDLSNKYTVSQLICQYAQVVLWFSHSGLLPEGLDDAVQLSRLCYNYPVIQNYYTSRRQKCERLSRGKWNPDCLMIDGMVSQLGDRVEKLWKRDEGGTGKYPPTSLHALLDIYLLEDVTEASKHSITIYLLLDIMYSFPNKTDTSIESFPTAFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPVSWQHSKIIQAFMSQGEPRQALRYIQTMRPTVSTDSDVTLHLTVLLFNRCMVEAWDLVRQHSSRLNIEELLKHTYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASIQNHEFLLVHHLQRANYIPALKLNQTLKINLMNDRDPRLRERSVARNSILDQYGKILPRVQRKLAIERAKPYRLSASSVLREVSRPKPLSAVPKQAVTGTVFTRSTFINNVLSKIGEVWASSEPKNSLSVYNSPKIEAPSPVVYSLPDLELPEAFVGTPISKASQKISRLLDLVVQPVPQPSQCLGFIQHIPPRSPLYLVSSSLSLSSQLKESRQNASRASELHLLETPLVVKKAKTLAMSVTSSGFAEFTPQSILRSGLRTTPLASPSLSPGRSLTPPLRLKETRISFMEEGLTTEWAAGAADDSKTKVFITEPFHKCGVPAETGWQKNKDKTTSFSMSSPEKDHQEVDVQSQDTTSQGLEKLDISVEHSNASTRSDQTTLEYQDAPLPEDLEDIFMASMPPSSSTELITNLTGQSEKDSDKDVFESEVTPPDLEKQMGTLEDAETRDLLVAEGALSELNHLSPSQGVEASCVSSIHEGSILTPESMVPVLDKGLVSIETCTSTIRTGNNKSVADVLGDNGSSGLLISESPAISEHRLDQEVALNVKEDHEIEVDVLKARVDLPEEKPPISDDPPDTQEIHVVEHEKVEVQDSGQEARNLSFNELYPSGTLKLQYNFDTIEKQFCDLPDSKDSAECDIAEVDRELFVAQSNFTLILEGEEGEIETGDSAASNVLAKAANAATEEKHTCSRENDSHRHVANLPSVLTSDQESQKVETLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHDNIPLISQKVMCSTKLAKTPFKTVQETSAVTINVSQINDMISSRTRKKRRVQDMSVKSAHQEESADVATPEMLGLSIMKKTRKTKEISGAFESASSDDKGISQNQQTPQNSVTPRRGRRKKEINQDTSEDINSVEQELEATPGRELRRVKSSQLLESVTEESSFRKDVKLSSVTKRTPKRIKKSVENQESVEVINDLKVSKIASPSRSTRKLRSACLETSESTAGESTEQQLPLQRNRRVRKREGSASDVVEDSKFDSSQRKPPAEFDTPATPRKRGRPRKTNPSEDVESKAVKGARSPETREGLNIQRRSTRNTPAKSGNTEVGKLALETSVFVPSEELATPVSSKKKPTKRTENQSQKRPLRSISEKCIDEEMTHKEVDDQEEKLLATVALTKSSRGTRTRSSKAVLLPDLSEPKNESLFSPPVSKIPRKEKAKKIEAPAQLKELVSDLSSQFVFSPPALRTRQKNLTNTSKLIDKLEDDAPSVETVEKQQVKRARTTKTRQASKNTEKESWSPPPVEVKLISPLASPVDGVKSRPRRAAEVTGKTLGRSRKKVSSFPKQVLRRKML", "length": 2374, "header": "tr|A0A5G2R3A1-1|A0A5G2R3A1_PIG Isoform 1 of AT-hook containing transcription factor 1 OS=Sus scrofa OX=9823 GN=AHCTF1 PE=1 SV=2 CANONICAL=A0A5G2R3A1-1" }, "locus": { "chromosome": "10", "start_pos": 15120342, "end_pos": 15042783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080963.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080963.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070827.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070827.2" } ] } }, { "isoform_ac": "F1S8P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1/entry#F1S8P4-1", "sequence": { "sequence": "MATERRSESMRDLTAQVTSDLLQFPEVTIQALGEDEITLESVLRGKFAAGRNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPIVLAVKEFSWQKRTGLLIGLEEFEGSVLCLYDLGLSRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSGSQNEVEASDLEVITGIPAEVPHIRENVMREGRHLCFQLVSPSGIAVSTLSYINRTNQLAVGFSDGYLALWNMKSMKREYYTQLEGGRVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLTGGGMFPVRGQTGNTKLLGCQSIEKFRSHGDREEGMNEALSPDTSVSVFTWQVNIYGQGKPSIYLGLFDINRWYHAQMPDSLRSGEYLHNCSYFALWSLDSVVSKTSPHYVLDVLVHERSLSRGVPPSYPPPEQFFNPSTYNFDATCLLNSGVVHITCTGFQKETLTFLKKSGPSLNEVIPDGYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGCIRRWITEEQPNSAANLRFVLEWTWNKVVFTKGEFDRLCAPLFDGSCRFIDPQTIQSIQQCSLLLSNLNTVLSCFATEAQEITERGVMDLSNKYTVSQLICQYAQVVLWFSHSGLLPEGLDDAVQLSRLCYNYPVIQNYYTSRRQKCERLSRGKWNPDCLMIDGMVSQLGDRVEKLWKRDEGGTGKYPPTSLHALLDIYLLEDVTEASKHSITIYLLLDIMYSFPNKTDTSIESFPTAFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPVSWQHSKIIQAFMSQGEPRQALRYIQTMRPTVSTDSDVTLHLTVLLFNRCMVEAWDLVRQHSSRLNIEELLKHTYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASIQNHEFLLVHHLQRANYIPALKLNQTLKINLMNDRDPRLRERSVARNSILDQYGKILPRVQRKLAIERAKPYRLSASSVLREVSRPKPLSAVPKQAVTGTVFTRSTFINNVLSKIGEVWASSEPKNSLSVYNSPKIEAPSPVVYSLPDLELPEAFVGTPISKASQKISRLLDLVVQPVPQPSQCLGFIQHIPPRSPLYLVSSSLSLSSQLKESRQNASRASELHLLETPLVVKKAKTLAMSVTSSGFAEFTPQSILRSGLRTTPLASPSLSPGRSLTPPLRLKETRISFMEEGLTTEWAAGAADDSKTKVFITEPFHKCGVPAETGWQKNKDKTTSFSMSSPEKDHQEVDVQSQDTTSQGLEKLDISVEHSNASTRSDQTTLEYQDAPLPEDLEDIFMASMPPSSSTELITNLTGQSEKDSDKDVFESEVTPPDLEKQMGTLEDAETRDLLVAEGALSELNHLSPSQGVEASCVSSIHEGSILTPESMVPVLDKGLVSIETCTSTIRTGNNKSVADVLGDNGSSGLLISESPAISEHRLDQEVALNVKEDHEIEVDVLKARVDLPEEKPPISDDPPDTQEIHVVEHEKVEVQDSGQEARNLSFNELYPSGTLKLQYNFDTIEKQFCDLPDSKDSAECDIAEVDRELFVAQSNFTLILEGEEGEIETGDSAASNVLAKAANAATEEKHTCSRENDSHRHVANLPSVLTSDQESQKVETLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHDNIPLISQKVMCSTKLAKTPFKTVQETSAVTINVSQINDMISSRTRKKRRVQDMSVKSAHQEESADVATPEMLGLSIMKKTRKTKEISGAFESASSDDKGISQNQQTPQNSVTPRRGRRKKEINQDTSEDINSVEQELEATPGRELRRVKSSQLLESVTEESSFRKDVKLSSVTKRTPKRIKKSVENQESVEVINDLKVSKIASPSRSTRKLRSACLETSESTAGESTEQQLPLQRNRRVRKREGSASDVVEDSKFDSSQRKPPAEFDTPATPRKRGRPRKTNPSEDVESKAVKGARSPETREGLNIQRRSTRNTPAKSGNTEVGKLALETSVFVPSEELATPVSSKKKPTKRTENQSQKRPLRSISEKCIDEEMTHKEVDDQEEKLLATVALTKSSRGTRTRSSKAVLLPDLSEPKNESLFSPPVSKIPRKEKAKKIEAPAQLKELVSDLSSQFVFSPPALRTRQKNLTNTSKLIDKLEDDAPSVETVEKQQVKRARTTKTRQASKNTEKESWSPPPVEVKLISPLASPVDGVKSRPRRAAEVTGKTLGRSRKKVSSFPKQVLRRKML", "length": 2281, "header": "tr|F1S8P4-1|A0A5G2R3A1_PIG Computationally mapped isoform of AT-hook containing transcription factor 1 OS=Sus scrofa OX=9823 GN=AHCTF1 PE=1 SV=4 CANONICAL=A0A5G2R3A1-1" }, "locus": { "chromosome": "10", "start_pos": 15120342, "end_pos": 15042864, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011885.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011885.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011581.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011581.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S8P4", "url": "https://www.uniprot.org/uniprotkb/F1S8P4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-SSC-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-SSC-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-SSC-68877", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "resource": "Reactome", "description": "Mitotic Prometaphase" }, { "id": "R-SSC-9615933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9615933", "resource": "Reactome", "description": "Postmitotic nuclear pore complex (NPC) reformation" }, { "id": "R-SSC-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K160-1", "protein_name": "AT hook containing transcription factor 1", "gene_name": "Ahctf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAEWSLRASLPRPWAGSSPSGTSLTRDPEPSRCSGAMETFVGRSPRTTAGAPSFSCVGVCSTWSCAGLGGSMQDLTAQVTSDLLQFPEVTIEALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPVVLAVKEFSWHKRTGLLIGLEEADGSVLCLYDLGISRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSCSQNEVEASDLEVITGIPAEVPHIRESVMREGRHLCFQLVSPSGVAISTLSYINRTNQLAVGFADGYLALWNMKSMKREYYTQLEGGRVPVYAVVFQEPENDPRNCCYLWAVQSTQESEGDVVSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLSGGMFPLRGQTSNTKLLGCQSIERFPSHGDREESMREALSPDTSVSVFTWQVNIYGQGEPSVYLGLFDINRWYHAQMPDSLRSGESLHNCSYFALWSLESVVSRTSPHHILDILVHERSLSRGVPPSYPPPEQFFNPSTFNFDATCLLNSGVIHVTCTGFQKETLTFLKKSGPTLNEVIPDSYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGYIRTWIIEEQPNSAANLRFVLEWTWNKVILTKEDFDRLCVPLFDGSCRFIDPQTIQSIQQCHLLLSNLSTVLSCFAMEAQGITERGLVDLNNKHMVTQLICQYAQMVLWFCHSGLLPEGLDDTLQLSRLRYNYPVIQNYYTSRRQKCERSPRGKWSRDCLLIDGLVSQLGDEVEKLWKRDEGGTGKYPPASIHALLDIYLLDNISEASKHAITIYLLLDIMYSFPNKTDTPIESFPTAFAISWGQVKLVQGFWLLDHNDYENGLDLLFHPVTAKPASWQHSKIIEAFMSQGEHKQALRYLQTMKPTVSSSSDVLLHLSVLLFNRCMVEAWNLLRQNSNTVNIEELLKHAYEVCQEMGLMEDLLKLPFTNTEQECLVNFLQSSSSVQNHEFLLVHHLQRANYISALKLNQTLKNNLTSDRDPRLRERSVTRNSILDQYGKILPRVQRKLAVERAKPYHLSTSSVFQEVSRPKPLSAFPKKALTGTVITRSTFISNVLSKIGEVWASHEPRNGISLFNSPKTEQPSPVVHSFPHPELPEAFVGTPISNPSQRISRLLDLVVHPIPQPSQRLEFIQQSPTRSPLCLLSSSLPLSSQLKRPHQQASRPSELLLLETPLIVKKAKSLALSATSSGFAEFTPPSILRSGLRTTSLASPSQSPGRSLTPPFRLKETRISFMEEGMNTHWTDTATDDRNAKAFVSTSFHKCGLPAETEWMKTNDKNTYFPLDVPAKVPQKVVAESLDTHSPRSLEKLDVSKDSTVSSRSDQTLEYHDAPSPEDLEGGVFVSPKPASSSTELTTNSMVQTEKDNDKNLFKSEGTPSAMEKQIGTIEASVEAFSEFSHLDPVERAEASLGVSSVREGETSTSKSKTSVLDGIVSIESRTSIPIADHNEFVANKVEDVESSESTTSKCPVTSERSLDKELTLNLKGDEMEAVVPKESVGLPEERPQTSAGPSDTQEIHLIGCEKLEVQNSEEVAKSLSFPELCPLGAHRPQYNFDVIEQQFRDLPDDKDSAECDVAEVDGELFVAQSNFSLILEGEEGEVEASDSNVLPKVTNIATKEKPVSCEEPDNEGHVTDLPSAVTGDQESHKVETLPYVPEPVKVAIAENLLDVIKDTRSKEATHVAAVEDVDEDRAVMIPKAAHPSRLTNSTPKTVKERRAETVSASQGDDSIAPRTLTRRQRALSLNVTSEQEPSAAATPQKKTRKVKETREFSESTCSDVKVAPENQLTAPSPSPSRRGRKKKDLGQGPLATSGAVEEPQATPERLRLRVQPPEPAAEETPSRAKAKLSSARKGTPRRLRKSIEDGPSADIVNEVRGRKAAGHGRTVRELRSASVEDTQKMEYEQDEERGDQQLPLKRKRVREREDSVSGVTEEPKLDSSQLTLQVGLDVPATPRKRGRRPKRVVPLGADGTTPGKEQTSPQKEGPVVRRSTRNTPARNVSTLEKPILVPNKEAATVMTSKKKPTKKSADGSPKGPFPAVSDLADEAAHRESTDQGVLTSAAFTTPSWSTRTRSRRTMLLTDISEPQTEPLLSSPSLKVPKKETKAKNMEAAAQLKELVSDISSRFVVSPPALRTRQKSTSNASKLLGELESNPKPVEIIEQKPKRSRTVKTKVSRNTGKGSSWSPPPIEIKLISPLASPVDEIKVSKPRKTAEVAGKTLGRGRKKPSSFPKQILRRKML", "length": 2312 }, "evidence": [ { "id": "A0A5G2R3A1", "url": "https://omabrowser.org/oma/group/A0A5G2R3A1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8N7T6T7-1", "protein_name": "Protein ELYS", "gene_name": "ahctf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRDLAAQVTSSLLRFPEVTIDALGEDEVTLDSVLHGKFTVGKSGLAWLACGPQLEVVHAVSGERFSAYHFSGVSEHPPTVLAVRDFCWLKRTGLLIGLEEAEGSMLCLYDLGISRVVKAVVIPGRITTIEPLVSYGGASASTQHLHQSLRWFFGVAAVVTDIGHVLLVDLCLDDLSCSQSELEASDLEVVNKSPSEIPRLREGVTQQGRHLCLQLSSPTGIGATALQYIQRTNQLAVGFSDGNLQLWNMKSLKKEYHSQLEGGRVPVYAFTFQEPENDPRNCCYLWAVQSAQDLEGDVVSLHLLQLAFGERKCLASGKIIYEGLEYCEERYSQDLNGTSFPLRAQATNTRLISCQTIEKFRHHPDRDDSMNEVASPDTSVSVFSWQVKSYGQGQPSTFIGVFDINRWYHAQMPDSLRTGESLRNCPYLAVWSLDCVIEMTAPCALLDILVHERSLSRGLPYTCPPPEQFFNPTTYNFDGSCLFNAGIVHFTCSGYQKETLCYLKKVAPSLGDSISNGYSRCLMSGLLSSRLADVQPSSLSQEEQLDAILCTAVETSSLGLITGCIRQWTTEEQPGSAVNLRYILEWAWNKVVHTKEELDEICAPLFDSSANFTDSQTLQLLQHSQRLLANLSTIFHCLLNEAQELTQKGLIGLMNKCMVSSLVSQYAQVVLWFCRTGLLPEGFDDDDVLQLSRPFYSHSIIKNYYIGQREELRRMAKDKWCADCLMIDGLVSQCGERLSELWKRDEGGTGHYPPPSLHALLDIYLLENIEESAKHAIVIYLLLDVMYSFPNKSGASVESFPTAFAIPIGLVKLVQGLWLLDHHDHESSLELLLHPATSHSLWSWQHERVLQALMCQQKHSIALRYLHVMKPPLCTTSQAKLCLSVFLHNRCIVEAWALLRQHCNKLNTEEVMRFLFETCQELGLMKELLKLPLGLAEQECLQRFLQSNGGFQNRELLMVHYLQQANYVPALQLNQTLKLNLAADRDPKMKERSNTRNSILNQYGKVLPRVQRKLAIERAKPYQHPTLIHRVKRPQPLSTVTKRSASENVMTRAAFINNVYSKIEEVWAGNNTTPESSPFKSPKESEMQVPSRHPSSPDLPEAFVGTPINKLTKRMSRLLDLVVQPSSQNSPESSNMPGTPTRSITSWAGPKSISKAPELSLLQTPQVVKRARALASGPVFSAFTPQSILRSSLRPTPVATPSASPGRSITPPLRPKESRITFIEDADSPEAPKGSVHWNNGISVNREHNTPKRSSPPAKASIGVWSEHSDAEEEDVDMKMTCMPSLGEQENPDVESETGSSIKEIPLAESTKVLPTLVRRPSLGQEASLVSNQSDTTLEFHDAPAPEDLLITLKEQQANNSVDREVTVRLPNTFEEHTAPVERNTTVDLPSLMLPEKEKDNSRGDLSNAERSLGIQEAQNEEECVNITNDVVENVSEEQLKGISEAQVLKIDVVIKPELVVPVQEPSSESVPEMSEHLDTRDPTEAEESLNTSSFFVEALSVPPPLEPLNQSMEENAAYNTIDQPPVVKVSEAASEKAVSEASVSKSSMGELVNHEQVTIEPEINEQCQEESMETSDLDAFVEQHLFGPDLTQSNIRESSEKSLKSDPVCDIKDYQTTSENAADLKTQTSETGTSESRSVVSLNDSDELSSAESAEDSDDEESEEESGDEKVEDSGSEVEIIDEIQGNGRSNHQRPSTLYVEELPSHGQYFQDQANAVLSLITPEAQLKVLDTDIPEEEGEVVMVGLGPADLDEEDGMCYTELRPSTTLLVPVELADQQQTHLIDRGTMETLSGAPEDSEGFTLMLDPDVEELPDASELDHNAVLLPLHEPEEHQDMENKPTTNSEVVILEHTFDVPDNKLEEVNDLVSDIEPVVSGSSKIEEQPAEVLQTVEQIITPEPETCLSNGDGPDSGPSKMQDAPHTPRSVKVFETPSPENALPLEQLLEKDNEVSVLDTGVSAIAKDVAPANQIDTTPSLAEEVEELNTTKQAARPKSPGRPKSPGRPKSPARTKVERPGKDTEEIKENLKEVQHSPSRRTRKTVTFPVPNLEADKDLTEEEQMDSQVPSTPRRVTRSGKQLQDCEVPVTPRRSTRKTDTEQHISENHQDMPSEKVSKPASPARKTPQKATPRKGSRKTRSTAVDDDEGDDNDDDDDDKAALTEHIPNEISEIQLRHSTRKSQPKTADRPEAQQEVPVERAQPNKAHSSPSRVTRKSTRGLTLESFQQDPAEDATTLNQPLRTPPRSRRKTVATTAEKAVNETYVVDDAQLQSVSRRLTRSRHWNQGDGLDKERLDLIPLEVHAESPQADALVERLKNEEASEKNVSVVTEIIRAKRRTTRSAAPPMNETQTIGFEESKLVSEEIEKHESKSLASARRTRASKLSENSASVDDSVAPVAEQRRTRGRKKGSAVPNEVEIPEILPVPQMLSEGGESDLQSKGDNGLVDDVPVETEVVKPRKKRTTRTKAAPEPPPPVEISFISPFGSPAETISKTEKRTEDKETPSLRMNLRRKRMMDAIFPKPVTRRKKL", "length": 2527 }, "evidence": [ { "id": "A0A5G2R3A1", "url": "https://omabrowser.org/oma/group/A0A5G2R3A1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0Y5R2-1", "protein_name": "AT-hook containing transcription factor 1", "gene_name": "AHCTF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQDLRAQVTSSLLQFPEVTIQALGEDEITLDSVLRGKFSGGRNGLAWLACGPQLEVVNSVTGERLSAYCFSGVSEQPPTVRVVKEFSWQKRTGLLVGLEEAEGSVLCLYDLGISRVVKAVVLPGRVTAIEPIINHGGASVSTQHLHQSLRWLFGVAAVVTDVGHVLLVDLCLDDLSCSQNEIEASDLEVVTGIPAEVPQRREAVTREGRHLCFQVQNPSGTAISTLCYISRSNLLVVGFSDGYLSLWNMKTLKREYHSQLEGGRIPVYAVTFQEPENDPRNCCYLWAVQSTQESEGDVLSLHLLQLAFGDRKRLASGQVMYEGFEYCDERYSLDLTGGAFPLRGQTSNTKLLSCQTVEKFRNHIDREDSVNEVISPDTSVSIFSWQVNTYGQGKPSTYLGVFDINRWYHAQMPDSLRPEEFLHNCPYFALWSLDAVTSVTSPNLILDVLVHERSLSRGVPPSYPPPEQFFNPSTYNFDGTCLLNSGVVHMTCTGFQKETLNFLKKSGPSISEAICDSYNRCLVAGLLSPRLVDVQPSSLSQEEQLEAVLSAAVQTSSLELLTGYIKHWTSEEQPSSAASLRFVLEWTWNKVIYTKDEFDQICVPLFDGSCNFIDPQTMQSLQHCQLLLSNLSTVLNCFLTEARELTEKGVTDLTNKQVVTSLISLYAQVVIWFCRSSLLPEGLDDDMHLSRPFYNYPLIQSYYTSHRQKLERLSRGRWDSDCLMIDGMVSQLGEQAQKLWRRDEGGTGKYPPASLHALLDLYLLENIEENYKHAITIYLLLDIMHSFPNKTETSIDSFPTVFAIPWGLVKLIQGFWLLDHNDFENSLALLFHPATIKTVPWQHMRIIQSLMCQGEHRRALRYIQMMKPAMSSSSEVQLFLTVLLSNRCMVEAWSLLQQHTTKLNVEELLKHMYEICQEMGLMEDLLKLPFTDTEQECLEKFLQTNGGVQNHEFLLVHHLQRANYIPALQLNHSMKVNLMNDRDPRLRERAVARNSILDQYGKILPRVQRKLALERAKPYRLPSSVFREVSRPKPLSTVAKQAHAGNVHTRATFISNVLSKIGEVWVGNEQKNSFSQCDSPRVAEPPVITHPLPDAELPDAFVGTPITKFSRKCSRLLDLVVRPVPSCSPAQNDGWQSPCLPSTSYLESTSLKSNINGSSSQKKFSRASELNLLETPLVVKRAKVLVTSSSASGFAGFTPQSILRSSLRTTPLATPSASPGRSVTPPLRAKEPRISFREVNSNTKWAVGVTEDDKAQSGASSEHCHGLVEDNWSGGRDKASLYTLSNPEIDHAEMEESLESIPGDGLEKMDVSKENSNVSVKSDQTTLEYHDAKSPSDFEDDVIFIAAKPASSFTEESTDFQEPEKENNEIIEDRPFQVEHTDSSELGKEAGFLEETTPECPALPKDGKLVFKAAEAVTSRTSREDETTHEEPKMSSASEEKSTLTVTNPQLSESPEADSESVISVLDSEDVIRTLSENRPEEKLDLPEERNLENEVEVNASFPQEEIHSSNSLPKTEEINVLKEVAVKAQTSEESPETSPYSELHPSGNLQYNYDTIEQQFAYDLPDNKDGECFAVEGDGELFISQSNFTLVLEGEEGEGEMGDLALADASKAAVTTTDEKPANSLGSTENEEHVKNSVSTVTSDQESQNIAESLPYVPEPIKVAIAENLLDVIKDTRSKEFTSEVVEQSIHESIGKKVTRFRKSKTPLTAVPEGADDETSIHQVEYVVTPRTRARRQLSRTLIIPSADDQQVLKTDKPVLFGLSPRRSTRQTKEAPETSSLVTVENTQDEQIPVAPATPRRRGRKPKQANLENVESSQSDGQTLSSSTQSIAVTPRRLRRAKEAASELMEDANEEISLAEGTIVASTTPRRTRGGKSSAGDQEAGQSSTDRRIKSAVSPSRSARKLKGSSLPLAQNTTMAQELQPSDQLLLPGPTKRGRRIKMSSSDISENSDLDLSKSSLPQTELKLPITPRRSARKAAQNLSADMESVSAREDLPSGGEVEILDTPRRRTRKVAHAKPEKTDTIEKTPEQSNEQSTTPRTTIRSGFRGRKRQLSSILEENTREEVFPEGTDGSPLLLTDINTSGYDETSRTVTDRVRRNRSRKTSMHQELSVEENESFFFSPPLTKLTKKFKAGKADQHVQDLDPDLSSQFVFSPPLLRSRRKNVSSTPQIVEEPALPTKEEEDIKSIESVGKQKLKRGRPARSKVKKASRTTRKEVSWSPPPVEIKFISPFGSPVEEMKSKQKETTDATEKTVQKNKKRLSNFPKPVVRRKML", "length": 2277 }, "evidence": [ { "id": "A0A5G2R3A1", "url": "https://omabrowser.org/oma/group/A0A5G2R3A1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8CJF7-1", "protein_name": "Protein ELYS", "gene_name": "Ahctf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQDLTAQVTSDLLHFPEVTIEALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPVVLAVKEFSWHKRTGLLIGLEEADGSVLCLYDLGISRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSCSQNEVEASDLEVITGIPAEVPHIRERVMREGRHLCFQLVSPLGVAISTLSYINRTNQLAVGFSDGYLALWNMKSMKREYYTQLEGGRVPVHAVAFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLAGGTFPLRGQTSNTKLLGCQSIERFPSHGDREESMREALSPDTSVSVFTWQVNIYGQGKPSVYLGLFDINRWYHAQMPDSLRSGESLHNCSYFALWSLDSVVSRTSPHHILDILVHERSLNRGVPPSYPPPEQFFNPSTFNFDATCLLDSGVIHVTCAGFQKETLTFLKKSGPTLNEVIPDSYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGYIRTWIIEEQPNSAANLRFVLEWTWNKVVLTKEEFDRLCVPLFDGSCRFIDPQTIQSIQQCHLLLSNLSTVLSCFAMEAQGITERGLVDLSNKHMVTQLLCQYAHMVLWFCHSGLLPEGLDDALQLSRLRYNYPVIQNYYTSRRQKSERSPRGKWNHDCLMIDGLVSQLGDEVEKLWKRDEGGTGRYPPASIHALLDIYLLDNITEASKHAITIYLLLDIMYSFPNKTDTPIESFPTAFAISWGQVKLVQGFWLLDHNDYENGLDLLFHPVTAKPASWQHSKIIEAFMSQGEHKQALRYLQTMKPTVSSSNEVILHLTVLLFNRCMVEAWNLLRQNSNRVNIEELLKHAYEVCQEMGLMEDLLKLPFTNTEQECLVKFLQSSTSVENHEFLLVHHLQRANYISALKLNQILKNNLMSDRDPRLRERSVTRNSILDQYGKILPRVQRKLAVERAKPYHLSTSSVFHEVSRPKPLSAFPKKAITGTVLTRSTFISNVLSKIGEVWASHEPRNGVSLFNSPKTEQPSPVVHSFPHPELPEAFVGTPISNTSQRISRLLDLVVHPVPQPSQCLEFIQQSPTRSPLCLLSSSLPLSSQFKRPHQNTSRPSELLLLETPLIVKKAKSLALSATSSGFAEFTPPSILRSGFRTTPLASPSLSPGRSLTPPFRVKETRISFMEEGMNTHWTDRATDDRNTKAFVSTSFHKCGLPAETEWMKTSDKNTYFPLDVPAKGPQKVVAESLATHSGRLEKLDVSKEDSTASTRSDQTSLEYHDAPSPEDLEGAVFVSPKPASSSTELTTNSTLQTERDNDKDAFKSEGAPSPVKKQIGTGDAAVEAFSELSRLDPVERAEASFAVSSVCEGETSTSNSKTSVLDGIVPIESRTSILTADHKESVANTVADVESSGSTSSKCPVTSERSLGQKLTLNLKEDEIEAHVPKENVGLPEESPRISAAPSDTHEIHLIGCENLEVQNSEEEAKNLSFDELYPLGAEKLEYNLSTIEQQFCDLPDDKDSAECDAAEVDGELFVAQSNFTLILEGEEGEAEASDSAAPNMLPKATKEKPVCHREPHNQERVTDLPSAVTADQESHKVETLPYVPEPVKVAIAENLLDVIKDTRSKEATPVAAGEAGDEDGAVIVSKAAHSSRLTNSTPKTVKEPHAETVNTSQNDDMVSSRTLTRRQHALSLNVTSEQEPSAVATPKKRTRKIKETPESSERTCSDLKVAPENQLTAQSPPAPRRGKKKDVSQGTLPSSGAVEPEPEPQGTPGRLRLRTQPPEPAAEETPSRTKVRLSSVRKGTPRRLKKSVENGQSTEILDDLKGSEAASHDGTVTELRNANLEDTQNMEYKQDEHSDQQLPLKRKRVREREVSVSSVTEEPKLDSSQLPLQTGLDVPATPRKRGRPRKVVPLEADGGTTGKEQTSPQKKDVPVVRRSTRNTPARNVSTLEKSVLVPNKEAALVVTSKRRPTKKSAEESSKDPSAAVSDLAGGAAHTESADRRDGLLAAAALTPSAQGTRTRSRRTMLLTDISEPKTEPLFPPPSVKVPKKKSKAENMEAAAQLKELVSDLSSQFVVSPPALRTRQKSISNTSKLLGELESDPKPLEIIEQKPKRSRTVKTRASRNTGKGSSWSPPPVEIKLVSPLASPVDEIKTGKPRKTAEIAGKTLGRGRKKPSSFPKQILRRKML", "length": 2243 }, "evidence": [ { "id": "A0A5G2R3A1", "url": "https://omabrowser.org/oma/group/A0A5G2R3A1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WYP5-1", "protein_name": "Protein ELYS", "gene_name": "AHCTF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRDLRAQVTSGLLPFPEVTLQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSITGERLSAYRFSGVNEQPPVVLAVKEFSWQKRTGLLIGLEETEGSVLCLYDLGISKVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLVDLCLDDLSCNQNEVEASDLEVLTGIPAEVPHIRESVMRQGRHLCFQLVSPTGTAVSTLSYISRTNQLAVGFSDGYLALWNMKSMKREYYIQLESGQVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGNRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTSNTKLLGCQSIEKFRSHGDREEGVNEALSPDTSVSVFTWQVNIYGQGKPSVYLGLFDINRWYHAQMPDSLRSGEYLHNCSYFALWSLESVVSRTSPHGILDILVHERSLNRGVPPSYPPPEQFFNPSTYNFDATCLLNSGVVHLTCTGFQKETLTFLKKSGPSLNELIPDGYNRCLVAGLLSPRFVDVQPSSLSQEEQLEAILSAAIQTSSLGLLTGYIRRWITEEQPNSATNLRFVLEWTWNKVVLTKEEFDRLCVPLFDGSCHFMDPQTIQSIQQCYLLLSNLNIVLSCFASEAREITERGLIDLSNKFVVSHLICQYAQVVLWFSHSGLLPEGIDDSVQLSRLCYNYPVIQNYYTSRRQKFERLSRGKWNPDCLMIDGLVSQLGERIEKLWKRDEGGTGKYPPASLHAVLDMYLLDGVTEAAKHSITIYLLLDIMYSFPNKTDTPIESFPTVFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPLSWQHSKIIQAFMSQGEHRQALRYIQTMKPTVSSGNDVILHLTVLLFNRCMVEAWNFLRQHCNRLNIEELLKHMYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASVQNHEFLLVHHLQRANYVPALKLNQTLKINVMNDRDPRLRERSLARNSILDQYGKILPRVHRKLAIERAKPYHLSTSSVFRLVSRPKPLSAVPKQVVTGTVLTRSVFINNVLSKIGEVWASKEPINSTTPFNSSKIEEPSPIVYSLPAPELPEAFFGTPISKASQKISRLLDLVVQPVPRPSQCSEFIQQSSMKSPLYLVSRSLPSSSQLKGSPQAISRASELHLLETPLVVKKAKSLAMSVTTSGFSEFTPQSILRSTLRSTPLASPSPSPGRSPQRLKETRISFVEEDVHPKWIPGAADDSKLEVFTTPKKCAVPVETEWLKSKDRTTSFFLNSPEKEHQEMDEGSQSLEKLDVSKGNSSVSITSDETTLEYQDAPSPEDLEETVFTASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNLEDAETKDLLVAAEAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVETYTPAIRANDNKSMADVLGDGGNSSLTISEGPIVSERRLNQEVALNLKEDHEVEVGVLKESVDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTIDQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSSYPKQILRRKML", "length": 2266 }, "evidence": [ { "id": "A0A5G2R3A1", "url": "https://omabrowser.org/oma/group/A0A5G2R3A1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VWE6-1", "protein_name": "Protein ELYS homolog", "gene_name": "Elys", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEWHEVELDGSRTIAFPERIVPGFGREPSAHLDAAEYLGGIIRDGQWGWVTWRYGSDATLLVCSMSTGDYLSWHCFWSESDDLGPRKSIRCVEELFPGEHERPAMLAICLESWNSGDQRPIDCPLSTQVLIYAIRNSQVLRRFDLHGITCSALTFLDKRIYGLTRLRRFKGCLAVATEEGTVLLVDLNSDSLQASTQRRSLCSPSSKDEPSDGNLYFVSSEESKRQLSSKLTHCRSKGAHLAVRMDVASIGISCLMGISMAPGYAAGLEDGRILIYDLINFDVTTDLNSPVKRKGVNRAVKRMCLIMPPDDPKPCFYICALYQNIDVLQMMLHSVCYRGSYRDRETHTIRFKDYRSRTVRNRQILDGGICSVIGCATASTFSFAGDNGTLLIVISWHSSADKKNKLVLFDINQWYKDEMPTSVHKNEVPNYMSGYILSGLQTGLALDLRSTTILHFVSLQRYDEHFYPNSLTFDCSLLTPTGKRYYAQDGVQHRFLNALRCDRATLFLRPQIYHEDIVRLRLLPQFCELNPNATFSKIAMYELILSVALEHNCGALLNDCARSWMDGSFLCNMIDNTQLSLSTLTNWILKRAGQIKTRCSELCHGIFDYGGYPLDQRERREFQVLSGQLRELVRLQSYIVEQGRRRLTSSILDDCRANERALKTVLEYQRVLLWFIDHGLLPEGQHMDNLVPGEQAFVRLQHEYSEKRAQGKILYIDSLGKRASFPEPYPPDSLHAYIHLMLSPDIELCHKHALILYLLMDLNQQLVGRFQIAFQLDKDLATSLRCFWYLDHGDYERGVEELYKEPAPAKNLKSWQMRLLIDKLLAEGAVKAAKKVVSRPPGPLSSALHMKVLLANENITEAFQIARLDDDEDGQPLLERFFRHCIEIRRFKVLAELYLREPEERLLYSLLRQCRSRQTDCVQLIMLLQKSKFIEAVSFMDEVAAERERDESSNTILPAYSATMGPVTQNIAGTYLRIRDTLEPYQKTGPLEPFSCQLVKQNASGQLGGIFQSSAVSAHWATQCESPPKMTPVSIQSKIGYTNVPFLRHAQYGHSELPLPRRIVKPVPHQVVEKRQRELEDQRTNLQDQRQLGTERPNKRPCLMVERMVEDVKDYVRSIREKSSNQMEQEEVKQNEATNLLQPPNFLQARQSTTIRQSSSSPQPIPPILKGSGAVDAVKRAPPVATFTALAGPKRFRFVPPIPLRTDKSDKSTEMGSEGAAEGEEETDEIIVEIESRSEPRSACSYESDEEDEFLSPLVSANVSLVDPVPSRNSPHYFAPPAGPQPRNSLLHGGNGSGSKIGTATGSESSSGFGSFSTVQPAQTSSHSQFVPTVCSSKMGETQSQVFSSGSCGIKISERTTICGEMESTDLGAELTAAPSAQWSLPSARPAIQGHHQMMDTTLGMSTYDVASLEQQDTQDVENEEELKLGDTKSLEEQQNPQDEQKPEQEQDQDEDQAQEPLATGGQLAFLSNSEGTAQEPLSSPIYSLSSEDSNVSSAGIRNPMLPTLHTDDPMYSIVVESPGSITTSRSVTHTPTSFLPSDTNVSQTSSPQAPHGEDGDGTPISLYRANSLETVDDLDTTKGSLEEEEEYDDDDCVIALDGTEVRGYVARPQQSAASSSAELFAFKDECQEEAAGVPSPFLSLGATVNSDSDVADTIVLDSDEETAKEKDTQPEQRKDWPMEEETPSNESVATVEFSEQKQPRADMDIGMEVDAVPDVLEVLEVPEMEPLPVLSDVDIEMAVDEVPNVLEVLEVPELEPLPAGQATQSSGLGEIPEEDVDAEAEEQVVVKVEHVADEQPKEGDKTESKEASEEETQHNPEPLLPEEEDSRHSLKLIFSGDEDEEEQDVPTRAIHTLRPRRSFTEHQDSPRTLRPRRVSQEHRDSPTPVAGRTMSLRSTDAPTLSPASNPPVSTPKRRGLQHKYLLEVIDEHSPSDLSLPRTRSRTRLSVDSEATSSRPGTPTMTKARGKRATSQAPPTASPSVRRSLRGHSEPPAALSAQLVRKPKTARAGVRSRKTSSGVQSPVAVSPTPIDAPIDVPDSTAPEEEQPRLRRTARRRISELSDQSANGTGDLRSEASSSRTGSKSNSAASTQNRELRPRLRRTSKSEH", "length": 2111 }, "evidence": [ { "id": "A0A5G2R3A1", "url": "https://omabrowser.org/oma/group/A0A5G2R3A1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" } ], "pmid": "" }, { "name": "nuclear pore outer ring", "id": "GO:0031080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031080", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" } ], "pmid": "" }, { "name": "nuclear pore complex assembly", "id": "GO:0051292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051292", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1074, "end_pos": 1076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1266, "end_pos": 1268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1422, "end_pos": 1424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1462, "end_pos": 1464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1561, "end_pos": 1563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1571, "end_pos": 1573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1650, "end_pos": 1652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1702, "end_pos": 1704, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1743, "end_pos": 1745, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1838, "end_pos": 1840, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2161, "end_pos": 2163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2223, "end_pos": 2225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2273, "end_pos": 2275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2276, "end_pos": 2278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 892, "end_pos": 894, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R3A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" }, { "id": "PF16687", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16687" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELYS beta-propeller", "eco_id": "ECO_0000259", "start_pos": 103, "end_pos": 592, "start_aa": "Met", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R3A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3A1" }, { "id": "PF13934", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13934" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELYS-like", "eco_id": "ECO_0000259", "start_pos": 825, "end_pos": 1047, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1074, "end_pos": 1076 }, { "start_pos": 1266, "end_pos": 1268 }, { "start_pos": 1422, "end_pos": 1424 }, { "start_pos": 1462, "end_pos": 1464 }, { "start_pos": 1561, "end_pos": 1563 }, { "start_pos": 1571, "end_pos": 1573 }, { "start_pos": 1650, "end_pos": 1652 }, { "start_pos": 1702, "end_pos": 1704 }, { "start_pos": 1743, "end_pos": 1745 }, { "start_pos": 1838, "end_pos": 1840 }, { "start_pos": 2161, "end_pos": 2163 }, { "start_pos": 2223, "end_pos": 2225 }, { "start_pos": 2273, "end_pos": 2275 }, { "start_pos": 2276, "end_pos": 2278 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 527, "end_pos": 529 }, { "start_pos": 892, "end_pos": 894 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R4B1-1", "uniprot_ac": "A0A5G2R4B1", "uniprot_id": "A0A5G2R4B1_PIG", "mass": { "chemical_mass": 72691.0, "monoisotopic_mass": 72691.0 }, "refseq": { "ac": "NP_001245289", "name": "olfactomedin-like protein 2A precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245289" }, "gene_names": [ { "name": "OLFML2A", "type": "recommended", "evidence": [ { "id": "A0A5G2R4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1" } ] }, { "name": "OLFML2A", "type": "synonym", "evidence": [ { "id": "NP_001245289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245289" } ] } ], "protein_names": [ { "name": "Olfactomedin like 2A", "type": "synonym", "evidence": [ { "id": "A0A5G2R4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1/entry#names_and_taxonomy" } ] }, { "name": "Olfactomedin-like protein 2A", "type": "synonym", "evidence": [ { "id": "NP_001245289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245289" } ] }, { "name": "olfactomedin-like protein 2A precursor", "type": "synonym", "evidence": [ { "id": "NP_001245289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245289" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4B1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OLFML2A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1", "locus": { "chromosome": "1", "start_pos": 265604502, "end_pos": 265577704, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005593", "url": "https://www.ensembl.org/id/ENSSSCG00000005593" } ] } } ], "crossref": [ { "id": "A0A5G2R4B1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4B1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005593", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005593", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100154062", "url": "https://www.ncbi.nlm.nih.gov/gene/100154062", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154062", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154062", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR23192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001245289", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245289", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A1H6", "url": "https://www.uniprot.org/uniprotkb/A0A287A1H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4B1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAAAVPLRPGPGPLPLLLLPLLLLRAGPVRADSKVFGDVDQVRMTSEGSDCRCKCIMRPLSKDACSRVRSGRARVEDFYTVETVSSGTDCRCSCTAPPSSLNPCENEWKMEKLKKQAPELLKLQSMVDLLEGTLYSMDLMKVHAYVHKLASQMNTLEESIKANLSRENEVVRESMRHFSEQLKHYENHSAIMMSIKKELSSLGLQLLQKDAASVPGAPPATGPGSKAQDTAGGKGKDSNKHGSVQKTFVDKGLPRPPKEKLLKAEKLKKEGGKARFPQPTAKPRALAQQQAVIRGITYYKAGRKEMTEAMADNALKGTSWLEQLPPRVEGRLPEPNSAERDEAGGPRASEAADLAPGTPASGPTLTPTPTASPLPTEPPSRPEVPSPGREASCEGTLRAVDPPVRHHSYGRHEGAWMKDPAAKDDKIYVTNYYYGNSLVEFRNLENFKQGRWSNMYKLPYNWIGTGHVVYQGAFYYNRAFTKNIIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPAADDRDEAQPEVIVLSRLDPGDLSVHRETTWKTRLRRNSYGNCFLVCGILYAVDTYNQREGHVAYAFDTHTGADARLQLPFLNEHAYTTQIDYNPKERVLYAWDNGHQLTYTLHFVV", "length": 651, "header": "tr|A0A5G2R4B1-1|A0A5G2R4B1_PIG Isoform 1 of Olfactomedin like 2A OS=Sus scrofa OX=9823 GN=OLFML2A PE=4 SV=2 CANONICAL=A0A5G2R4B1-1" }, "isoforms": [ { "isoform_ac": "A0A287A1H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1/entry#A0A287A1H6-1", "sequence": { "sequence": "MTAAAVPLRPGPGPLPLLLLPLLLLRAGPVRADSKVFGDVDQVRMTSEGSDCRCKCIMRPLSKDACSRVRSGRARVEDFYTVETVSSGTDCRCSCTAPPSSLNPCENEWKMEKLKKQAPELLKSIKANLSRENEVVRESMRHFSEQLKHYENHSAIMMSIKKELSSLGLQLLQKDAASVPGAPPATGPGSKAQDTAGGKGKDSNKHGSVQKTFVDKGLPRPPKEKLLKAEKLKKEGGKARFPQPTAKPRALAQQQAVIRGITYYKAGRKEMTEAMADNALKGTSWLEQLPPRVEGRLPEPNSAERDEAGGPRASEAADLAPGTPASGPTLTPTPTASPLPTEPPSRPEVPSPGREASCEGTLRAVDPPVRHHSYGRHEGAWMKDPAAKDDKIYVTNYYYGNSLVEFRNLENFKQGRWSNMYKLPYNWIGTGHVVYQGAFYYNRAFTKNIIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPAADDRDEAQPEVIVLSRLDPGDLSVHRETTWKTRLRRNSYGNCFLVCGILYAVDTYNQREGHVAYAFDTHTGADARLQLPFLNEHAYTTQIDYNPKERVLYAWDNGHQLTYTLHFVV", "length": 615, "header": "tr|A0A287A1H6-1|A0A5G2R4B1_PIG Computationally mapped isoform of Olfactomedin like 2A OS=Sus scrofa OX=9823 GN=OLFML2A PE=4 SV=2 CANONICAL=A0A5G2R4B1-1" }, "locus": { "chromosome": "1", "start_pos": 265600502, "end_pos": 265577805, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053133.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053133.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037782.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037782.2" } ] } }, { "isoform_ac": "A0A5G2R4B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1/entry#A0A5G2R4B1-1", "sequence": { "sequence": "MTAAAVPLRPGPGPLPLLLLPLLLLRAGPVRADSKVFGDVDQVRMTSEGSDCRCKCIMRPLSKDACSRVRSGRARVEDFYTVETVSSGTDCRCSCTAPPSSLNPCENEWKMEKLKKQAPELLKLQSMVDLLEGTLYSMDLMKVHAYVHKLASQMNTLEESIKANLSRENEVVRESMRHFSEQLKHYENHSAIMMSIKKELSSLGLQLLQKDAASVPGAPPATGPGSKAQDTAGGKGKDSNKHGSVQKTFVDKGLPRPPKEKLLKAEKLKKEGGKARFPQPTAKPRALAQQQAVIRGITYYKAGRKEMTEAMADNALKGTSWLEQLPPRVEGRLPEPNSAERDEAGGPRASEAADLAPGTPASGPTLTPTPTASPLPTEPPSRPEVPSPGREASCEGTLRAVDPPVRHHSYGRHEGAWMKDPAAKDDKIYVTNYYYGNSLVEFRNLENFKQGRWSNMYKLPYNWIGTGHVVYQGAFYYNRAFTKNIIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPAADDRDEAQPEVIVLSRLDPGDLSVHRETTWKTRLRRNSYGNCFLVCGILYAVDTYNQREGHVAYAFDTHTGADARLQLPFLNEHAYTTQIDYNPKERVLYAWDNGHQLTYTLHFVV", "length": 651, "header": "tr|A0A5G2R4B1-1|A0A5G2R4B1_PIG Isoform 1 of Olfactomedin like 2A OS=Sus scrofa OX=9823 GN=OLFML2A PE=4 SV=2 CANONICAL=A0A5G2R4B1-1" }, "locus": { "chromosome": "1", "start_pos": 265600502, "end_pos": 265577805, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076389.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076389.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071173.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071173.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 369, "start_aa": "Thr", "end_pos": 369, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr369", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 371, "start_aa": "Thr", "end_pos": 371, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr371", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1H6", "url": "https://www.uniprot.org/uniprotkb/A0A287A1H6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154062", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154062", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4B1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4B1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4B1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4B1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4B1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1" } ], "pmid": "" }, { "name": "extracellular matrix binding", "id": "GO:0050840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050840", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4B1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R4B1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 651, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R4B1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4B1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4B1" }, { "id": "PS51132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Olfactomedin-like", "eco_id": "ECO_0000259", "start_pos": 393, "end_pos": 651, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 369, 371 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 188, "end_pos": 190 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R5J1-1", "uniprot_ac": "A0A5G2R5J1", "uniprot_id": "A0A5G2R5J1_PIG", "mass": { "chemical_mass": 52887.0, "monoisotopic_mass": 52887.0 }, "refseq": {}, "gene_names": [ { "name": "CABYR", "type": "recommended", "evidence": [ { "id": "A0A5G2R5J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1" } ] } ], "protein_names": [ { "name": "Calcium-binding tyrosine phosphorylation-regulated protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R5J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CABYR", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1", "locus": { "chromosome": "6", "start_pos": 108997297, "end_pos": 108969948, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003711", "url": "https://www.ensembl.org/id/ENSSSCG00000003711" } ] } } ], "crossref": [ { "id": "A0A5G2R5J1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5J1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003711", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003711", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12100", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12100", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MCKNPVE", "url": "https://omabrowser.org/oma/group/MCKNPVE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR15494", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15494", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15494:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15494:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02197", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02197", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287A1X7", "url": "https://www.uniprot.org/uniprotkb/A0A287A1X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5J1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISSKPRLVIPYGLKTLLEGVSRAILKTNPPNITQFAAVYFKELIVFREGNNSLDIKDLVKQFHQTKVEKWSEGRAQEKKLEGVKEPERTPVVSQEPKRMEKSTDTEEDNITLPQFSNKTTQFPSVHAELLSDPEDATEVAHGPSKPTTPKNATPPSSPPPAAVSPEFAYVPADPAQFAAQMLGNVSPVHSDQSDILMVDVATSMPVLSEEMLSSEVAEDTVVATPTVYSRGMVALQVLSQTSVRVDLGSDTTDDKAESPTASSFPLQVEQEPPVYDQAPEVPLQADIEVTSTMHIASIYKDEPVIEGVPYVEQTPEHIVTPFSDHVARPKGNEQSPPLSPILAVGKTASGVSEKSWGSTKFVQLESAKDDSSVESYVEADGATKAVSAENSMHLEVEISALVPGSTGQEESWANPAAQETEVKPASSSGPRLPVPEGLNEPEMEPEWEAAPGQGLMEPGKKTQNYTSGDICMVGNHLGKRSDVLVSNRI", "length": 490, "header": "tr|A0A5G2R5J1-1|A0A5G2R5J1_PIG Isoform 1 of Calcium-binding tyrosine phosphorylation-regulated protein OS=Sus scrofa OX=9823 GN=CABYR PE=1 SV=2 CANONICAL=A0A5G2R5J1-1" }, "isoforms": [ { "isoform_ac": "A0A287A1X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1/entry#A0A287A1X7-1", "sequence": { "sequence": "MISSKPRLVIPYGLKTLLEGVSRAILKTNPPNITQFAAVYFKELIVFREGNNSLDIKDLVKQFHQTKVEKWSEGRAQEKKLEGVKEPERTPVVSQEPKRMEKSTDTEEDNITLPQFSNKTTQFPSVHAELLSDPEDATEVAHGPSKPTTPKNATPPSSPPPAAVSPEFAYVPADPAQFAAQMLGNVSPVHSDQSDILMVDVATSMPVLSEEMLSSEVAEDTVVATPTVYSRGMVALQVLSQTSVRVDLGSDTTDDKAESPTASSFPLQVEQEPPVYDQAPEVPLQADIEVTSTMHIASIYKDEPVIEGVPYVEQTPEHIVTPFSDHVARPKGNEQSPPLSPILAVGKTASGVSEKSWGSTKFVQLESAKDDSSVESYVEADGATKAVSAENSMHLEVEISALVPGSTGQEESWANPAAQETEVKPAFSGELPQ", "length": 433, "header": "tr|A0A287A1X7-1|A0A5G2R5J1_PIG Computationally mapped isoform of Calcium-binding tyrosine phosphorylation-regulated protein OS=Sus scrofa OX=9823 GN=CABYR PE=1 SV=1 CANONICAL=A0A5G2R5J1-1" }, "locus": { "chromosome": "6", "start_pos": 108993281, "end_pos": 108974349, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065058.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065058.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037933.1", "url": "https://www.ensembl.org/id/ENSSSCP00000037933.1" } ] } }, { "isoform_ac": "A0A5G2R5J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1/entry#A0A5G2R5J1-1", "sequence": { "sequence": "MISSKPRLVIPYGLKTLLEGVSRAILKTNPPNITQFAAVYFKELIVFREGNNSLDIKDLVKQFHQTKVEKWSEGRAQEKKLEGVKEPERTPVVSQEPKRMEKSTDTEEDNITLPQFSNKTTQFPSVHAELLSDPEDATEVAHGPSKPTTPKNATPPSSPPPAAVSPEFAYVPADPAQFAAQMLGNVSPVHSDQSDILMVDVATSMPVLSEEMLSSEVAEDTVVATPTVYSRGMVALQVLSQTSVRVDLGSDTTDDKAESPTASSFPLQVEQEPPVYDQAPEVPLQADIEVTSTMHIASIYKDEPVIEGVPYVEQTPEHIVTPFSDHVARPKGNEQSPPLSPILAVGKTASGVSEKSWGSTKFVQLESAKDDSSVESYVEADGATKAVSAENSMHLEVEISALVPGSTGQEESWANPAAQETEVKPASSSGPRLPVPEGLNEPEMEPEWEAAPGQGLMEPGKKTQNYTSGDICMVGNHLGKRSDVLVSNRI", "length": 490, "header": "tr|A0A5G2R5J1-1|A0A5G2R5J1_PIG Isoform 1 of Calcium-binding tyrosine phosphorylation-regulated protein OS=Sus scrofa OX=9823 GN=CABYR PE=1 SV=2 CANONICAL=A0A5G2R5J1-1" }, "locus": { "chromosome": "6", "start_pos": 108993499, "end_pos": 108974349, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073271.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073271.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065850.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065850.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 261, "start_aa": "Thr", "end_pos": 261, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr261", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1X7", "url": "https://www.uniprot.org/uniprotkb/A0A287A1X7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "O75952-1", "protein_name": "Calcium-binding tyrosine phosphorylation-regulated protein", "gene_name": "CABYR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRGNTTMDIKDLVKQFHQIKVEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEIEPEGESTAE", "length": 493 }, "evidence": [ { "id": "A0A5G2R5J1", "url": "https://omabrowser.org/oma/group/A0A5G2R5J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1" } ], "pmid": "" }, { "name": "sperm fibrous sheath", "id": "GO:0035686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035686", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R5J1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 490, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R5J1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5J1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R5J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J1" }, { "id": "SM00394", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00394" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RIIa", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 49, "start_aa": "Tyr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 261 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 118, "end_pos": 120 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXT7-1", "uniprot_ac": "A0A5G2QXT7", "uniprot_id": "A0A5G2QXT7_PIG", "mass": { "chemical_mass": 56436.0, "monoisotopic_mass": 56436.0 }, "refseq": {}, "gene_names": [ { "name": "TRIM35", "type": "recommended", "evidence": [ { "id": "A0A5G2QXT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase TRIM35", "type": "recommended", "evidence": [ { "id": "A0A5G2QXT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A5G2QXT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "E3 ubiquitin-protein ligase that participates in multiple biological processes including cell death, glucose metabolism, and in particular, the innate immune response. Mediates 'Lys-63'-linked polyubiquitination of TRAF3 thereby promoting type I interferon production via RIG-I signaling pathway. Can also catalyze 'Lys-48'-linked polyubiquitination and proteasomal degradation of viral proteins such as influenza virus PB2. Acts as a negative feedback regulator of TLR7- and TLR9-triggered signaling. Mechanistically, promotes the 'Lys-48'-linked ubiquitination of IRF7 and induces its degradation via a proteasome-dependent pathway. Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7#function" }, { "database": "UniProtKB", "id": "ARBA00059140", "url": "https://www.uniprot.org/uniprotkb/ARBA00059140#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TRIM35", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7", "locus": { "chromosome": "14", "start_pos": 11027190, "end_pos": 11051972, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000033325", "url": "https://www.ensembl.org/id/ENSSSCG00000033325" } ] } } ], "crossref": [ { "id": "A0A5G2QXT7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXT7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000033325", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033325", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16599", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16599", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287A1X8", "url": "https://www.uniprot.org/uniprotkb/A0A287A1X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1X8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGPAASPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVTRCWEVQVAPTCPVCKDRAAPSDLRPNHTLNNLVEKLLREEAEGARWTGHRSPRLCRLHRGQFSLFCLDDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALLEKAKAFWAMRRSYEAIVKHNQVEAARLEGRIRQEFDKLREFLRVEEQSILDAMAEARQKQLLAEEKMKQLAEDMEALAHEVERLQVEMKEDDISFLMKHKSRKRRLFCTMEPEPVQPGMLIDICKYLDSLQYRVWRKMVMCVESVPFSFDPNTAAGWLSVSDDLTSVTNHDYRVQVENPERFPSAPCLLGSCVLSQGSHAWEVDLGTLPSWRVGVVRWRQDAGSEGRSHSCYHDTRSGFWYVCRTRGVDGDHCVTSDPATSPLVPAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGEVRPYFYVGGSRGDGPPEPLRICPLRITVKEELDG", "length": 492, "header": "tr|A0A5G2QXT7-1|A0A5G2QXT7_PIG Isoform 1 of E3 ubiquitin-protein ligase TRIM35 OS=Sus scrofa OX=9823 GN=TRIM35 PE=4 SV=1 CANONICAL=A0A5G2QXT7-1" }, "isoforms": [ { "isoform_ac": "A0A287A1X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7/entry#A0A287A1X8-1", "sequence": { "sequence": "MEPGPAASPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVTRCWEVQVAPTCPVCKDRAAPSDLRPNHTLNNLVEKLLREEAEGARWTGHRSPRLCRLHRGQFSLFCLDDKELLCCSCQADPRHQGHRVQPVKDTAHDFRVEAARLEGRIRQEFDKLREFLRVEEQSILDAMAEARQKQLLAEEKMKQLAEDMEALAHEVERLQVEMKEDDISFLMPLLHDGARARPARHAHRHLQVPGLPAVPRLEEDGHVCRICAFQL", "length": 265, "header": "tr|A0A287A1X8-1|A0A5G2QXT7_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM35 OS=Sus scrofa OX=9823 GN=TRIM35 PE=4 SV=2 CANONICAL=A0A5G2QXT7-1" }, "locus": { "chromosome": "14", "start_pos": 11051773, "end_pos": 11034285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040166.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040166.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037924.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037924.2" } ] } }, { "isoform_ac": "A0A5G2QXT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7/entry#A0A5G2QXT7-1", "sequence": { "sequence": "MEPGPAASPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVTRCWEVQVAPTCPVCKDRAAPSDLRPNHTLNNLVEKLLREEAEGARWTGHRSPRLCRLHRGQFSLFCLDDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALLEKAKAFWAMRRSYEAIVKHNQVEAARLEGRIRQEFDKLREFLRVEEQSILDAMAEARQKQLLAEEKMKQLAEDMEALAHEVERLQVEMKEDDISFLMKHKSRKRRLFCTMEPEPVQPGMLIDICKYLDSLQYRVWRKMVMCVESVPFSFDPNTAAGWLSVSDDLTSVTNHDYRVQVENPERFPSAPCLLGSCVLSQGSHAWEVDLGTLPSWRVGVVRWRQDAGSEGRSHSCYHDTRSGFWYVCRTRGVDGDHCVTSDPATSPLVPAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGEVRPYFYVGGSRGDGPPEPLRICPLRITVKEELDG", "length": 492, "header": "tr|A0A5G2QXT7-1|A0A5G2QXT7_PIG Isoform 1 of E3 ubiquitin-protein ligase TRIM35 OS=Sus scrofa OX=9823 GN=TRIM35 PE=4 SV=1 CANONICAL=A0A5G2QXT7-1" }, "locus": { "chromosome": "14", "start_pos": 11051773, "end_pos": 11033723, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086168.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086168.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068957.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068957.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1X8", "url": "https://www.uniprot.org/uniprotkb/A0A287A1X8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "suppression of viral release by host", "id": "GO:0044790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044790", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" } ], "pmid": "" }, { "name": "negative regulation of mitotic cell cycle", "id": "GO:0045930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QXT7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 492, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QXT7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXT7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QXT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 137, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QXT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 283, "end_pos": 486, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QXT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXT7" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 61, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZ51-1", "uniprot_ac": "A0A5G2QZ51", "uniprot_id": "A0A5G2QZ51_PIG", "mass": { "chemical_mass": 34853.0, "monoisotopic_mass": 34853.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "B30.2/SPRY domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QZ51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51", "locus": {} } ], "crossref": [ { "id": "A0A5G2QZ51", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZ51", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000037259", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037259", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15819", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15819", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287ACN1", "url": "https://www.uniprot.org/uniprotkb/A0A287ACN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ACN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ACN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QA67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QA67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QA67-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QA67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW35", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW35-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ51-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5B6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5B6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7P7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RHK0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RHK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMTYPRDCCRKLPIMNENHKESQPKVDHVDDNFATCLLKLLVMVLIFYVFREECFGNKKRKGNDQLKENDQLRKENDQLRKENGKLQKEIDERKTQFRNGWQKSSLYPDWRKEFFQAVTITLDPDTAHPSLVLSEGNRRVTWGEKSQDLPENPQRFYSFPCVLGLQVITSGRCYWEVEVGDSQALDLGICRPHVMRKGGISIKPEDGFWAIRSYNDEYWALTSPETQLIPKEHPARVCIFLEYEEGRISFYNMTDKSHIHTFSQGSFEGPLKPFFRLWPSDSACLTICPVLEAAQNPLC", "length": 299, "header": "tr|A0A5G2QZ51-1|A0A5G2QZ51_PIG Isoform 1 of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QZ51-1" }, "isoforms": [ { "isoform_ac": "A0A287ACN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51/entry#A0A287ACN1-1", "sequence": { "sequence": "MINLEENDQLRKENGKLQKEIDERKTQFRNGWQKSSLYPDWRKEFFQAVTITLDPDTAHPSLVLSEGNRRVTWGEKSQDLPENPQRFYSFPCVLGLQVITSGRCYWEVEVGDSQALDLGICRPHVMRKGGISIKPEDGFWAIRSYNDEYWALTSPETQLIPKEHPARVCIFLEYEEGRISFYNMTDKSHIHTFSQGSFEGPLKPFFRLWPSDSACLTICPVLEAAQNPLC", "length": 230, "header": "tr|A0A287ACN1-1|A0A5G2QZ51_PIG Computationally mapped isoform of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A5G2QZ51-1" }, "locus": { "chromosome": "AEMK02000320.1", "start_pos": 33265, "end_pos": 26399, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047625.2", "url": "https://www.ensembl.org/id/ENSSSCT00000047625.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041571.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041571.2" } ] } }, { "isoform_ac": "A0A5G2QA67-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51/entry#A0A5G2QA67-1", "sequence": { "sequence": "MINLEENDQLRKENDQLRKENGKLQKEIDERKTQFRNGWQKSSLYPDWRKEFFQAVTITLDPDTAHPSLVLSEGNRRVTWGEKSQDLPENPQRFYSFPCVLGLQVITSGRCYWEVEVGDSQALDLGICRPHVMRKGGISIKPEDGFWAIRSYNDEYWALTSPETQLIPKEHPARVCIFLEYEEGRISFYNMTDKSHIHTFSQGSFEGPLKPFFRLWPSDSACLTICPVLEAAQNPLC", "length": 237, "header": "tr|A0A5G2QA67-1|A0A5G2QZ51_PIG Computationally mapped isoform of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QZ51-1" }, "locus": { "chromosome": "AEMK02000320.1", "start_pos": 33265, "end_pos": 26399, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087636.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087636.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060881.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060881.1" } ] } }, { "isoform_ac": "A0A5G2QNV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51/entry#A0A5G2QNV3-1", "sequence": { "sequence": "MMTYPRDCCRKLPIMNENHKESQPKVDHVDDNFATCLLKLLVMVLIFYVFREECFGNKKRKGNDQLKENDQLRKENGKLQKEIDERKTQFRNGWQKSSLYPDWRKEFFQAVTITLDPDTAHPSLVLSEGNRRVTWGEKSQDLPENPQRFYSFPCVLGLQVITSGRCYWEVEVGDSQALDLGICRPHVMRKGGISIKPEDGFWAIRSYNDEYWALTSPETQLIPKEHPARVCIFLEYEEGRISFYNMTDKSHIHTFSQGSFEGPLKPFFRLWPSDSACLTICPVLEAAQNPLC", "length": 292, "header": "tr|A0A5G2QNV3-1|A0A5G2QZ51_PIG Computationally mapped isoform of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QZ51-1" }, "locus": { "chromosome": "AEMK02000320.1", "start_pos": 33265, "end_pos": 11454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084055.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084055.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065740.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065740.1" } ] } }, { "isoform_ac": "A0A5G2QQZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51/entry#A0A5G2QQZ0-1", "sequence": { "sequence": "MMTYPRDCCRKLPIMNENHKESQPKVDHVDDNFATCLLKLLVMVLIFYVFREECFGNKKRKGNDQLRKENDERKTQFRNGWQKSSLYPDWRKEFFQAVTITLDPDTAHPSLVLSEGNRRVTWGEKSQDLPENPQRFYSFPCVLGLQVITSGRCYWEVEVGDSQALDLGICRPHVMRKGGISIKPEDGFWAIRSYNDEYWALTSPETQLIPKEHPARVCIFLEYEEGRISFYNMTDKSHIHTFSQGSFEGPLKPFFRLWPSDSACLTICPVLEAAQNPLC", "length": 279, "header": "tr|A0A5G2QQZ0-1|A0A5G2QZ51_PIG Computationally mapped isoform of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QZ51-1" }, "locus": { "chromosome": "AEMK02000320.1", "start_pos": 33265, "end_pos": 11454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080037.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080037.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066467.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066467.1" } ] } }, { "isoform_ac": "A0A5G2QW35-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51/entry#A0A5G2QW35-1", "sequence": { "sequence": "MMTYPRDCCRKLPIMNENHKESQPKVDHVDDNFATCLLKLLVMVLIFYVFREECFGNNQLKENDQLRKENGKLQKEIDERKTQFRNGWQKSSLYPDWRKEFFQAVTITLDPDTAHPSLVLSEGNRRVTWGEKSQDLPENPQRFYSFPCVLGLQVITSGRCYWEVEVGDSQALDLGICRPHVMRKGGISIKPEDGFWAIRSYNDEYWALTSPETQLIPKEHPARVCIFLEYEEGRISFYNMTDKSHIHTFSQGSFEGPLKPFFRLWPSDSACLTICPVLEAAQNPLC", "length": 286, "header": "tr|A0A5G2QW35-1|A0A5G2QZ51_PIG Computationally mapped isoform of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QZ51-1" }, "locus": { "chromosome": "AEMK02000320.1", "start_pos": 33265, "end_pos": 11454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068342.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068342.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069159.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069159.1" } ] } }, { "isoform_ac": "A0A5G2QZ51-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51/entry#A0A5G2QZ51-1", "sequence": { "sequence": "MMTYPRDCCRKLPIMNENHKESQPKVDHVDDNFATCLLKLLVMVLIFYVFREECFGNKKRKGNDQLKENDQLRKENDQLRKENGKLQKEIDERKTQFRNGWQKSSLYPDWRKEFFQAVTITLDPDTAHPSLVLSEGNRRVTWGEKSQDLPENPQRFYSFPCVLGLQVITSGRCYWEVEVGDSQALDLGICRPHVMRKGGISIKPEDGFWAIRSYNDEYWALTSPETQLIPKEHPARVCIFLEYEEGRISFYNMTDKSHIHTFSQGSFEGPLKPFFRLWPSDSACLTICPVLEAAQNPLC", "length": 299, "header": "tr|A0A5G2QZ51-1|A0A5G2QZ51_PIG Isoform 1 of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QZ51-1" }, "locus": { "chromosome": "AEMK02000320.1", "start_pos": 33265, "end_pos": 11454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087568.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087568.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070158.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070158.1" } ] } }, { "isoform_ac": "A0A5G2R5B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51/entry#A0A5G2R5B6-1", "sequence": { "sequence": "MMTYPRDCCRKLPIMNENHKESQPKVDHVDDNFATCLLKLLVMVLIFYVFREECFGNNQLKENDERKTQFRNGWQKSSLYPDWRKEFFQAVTITLDPDTAHPSLVLSEGNRRVTWGEKSQDLPENPQRFYSFPCVLGLQVITSGRCYWEVEVGDSQALDLGICRPHVMRKGGISIKPEDGFWAIRSYNDEYWALTSPETQLIPKEHPARVCIFLEYEEGRISFYNMTDKSHIHTFSQGSFEGPLKPFFRLWPSDSACLTICPVLEAAQNPLC", "length": 272, "header": "tr|A0A5G2R5B6-1|A0A5G2QZ51_PIG Computationally mapped isoform of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QZ51-1" }, "locus": { "chromosome": "AEMK02000320.1", "start_pos": 33265, "end_pos": 11454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082141.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082141.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065769.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065769.1" } ] } }, { "isoform_ac": "A0A5G2R7P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51/entry#A0A5G2R7P7-1", "sequence": { "sequence": "MMTYPRDCCRKLPIMNENHKESQPKVDHVDDNFATCLLKLLVMVLIFYVFREECFGNNQLKENDQLRKENDERKTQFRNGWQKSSLYPDWRKEFFQAVTITLDPDTAHPSLVLSEGNRRVTWGEKSQDLPENPQRFYSFPCVLGLQVITSGRCYWEVEVGDSQALDLGICRPHVMRKGGISIKPEDGFWAIRSYNDEYWALTSPETQLIPKEHPARVCIFLEYEEGRISFYNMTDKSHIHTFSQGSFEGPLKPFFRLWPSDSACLTICPVLEAAQNPLC", "length": 279, "header": "tr|A0A5G2R7P7-1|A0A5G2QZ51_PIG Computationally mapped isoform of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QZ51-1" }, "locus": { "chromosome": "AEMK02000320.1", "start_pos": 33265, "end_pos": 11454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077484.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077484.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066616.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066616.1" } ] } }, { "isoform_ac": "A0A5G2RHK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51/entry#A0A5G2RHK0-1", "sequence": { "sequence": "MYSGRNVLEIRKEKEMINLRKMINLEENDQLRKENDQLRKENGKLQKEIDERKTQFRNGWQKSSLYPDWRKEFFQAVTITLDPDTAHPSLVLSEGNRRVTWGEKSQDLPENPQRFYSFPCVLGLQVITSGRCYWEVEVGDSQALDLGICRPHVMRKGGISIKPEDGFWAIRSYNDEYWALTSPETQLIPKEHPARVCIFLEYEEGRISFYNMTDKSHIHTFSQGSFEGPLKPFFRLWPSDSACLTICPVLEAAQNPLC", "length": 258, "header": "tr|A0A5G2RHK0-1|A0A5G2QZ51_PIG Computationally mapped isoform of B30.2/SPRY domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A5G2QZ51-1" }, "locus": { "chromosome": "AEMK02000320.1", "start_pos": 33265, "end_pos": 16921, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074037.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074037.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070846.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070846.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QA67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QA67" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZ51-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 299, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZ51-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZ51" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZ51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ51" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 294, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 252, "end_pos": 254 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZJ2-1", "uniprot_ac": "A0A5G2QZJ2", "uniprot_id": "A0A5G2QZJ2_PIG", "mass": { "chemical_mass": 106556.0, "monoisotopic_mass": 106556.0 }, "refseq": { "ac": "XP_020921638", "name": "reversion-inducing cysteine-rich protein with Kazal motifs isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921638" }, "gene_names": [ { "name": "RECK", "type": "recommended", "evidence": [ { "id": "A0A5G2QZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ] }, { "name": "RECK", "type": "synonym", "evidence": [ { "id": "XP_020921638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921638" } ] } ], "protein_names": [ { "name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "type": "recommended", "evidence": [ { "id": "A0A5G2QZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2/entry#names_and_taxonomy" } ] }, { "name": "reversion-inducing cysteine-rich protein with Kazal motifs isoform X3", "type": "synonym", "evidence": [ { "id": "XP_020921638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921638" } ] } ], "function": [ { "annotation": "Functions together with ADGRA2 to enable brain endothelial cells to selectively respond to Wnt7 signals (WNT7A or WNT7B). Plays a key role in Wnt7-specific responses: required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation. Acts as a Wnt7-specific coactivator of canonical Wnt signaling by decoding Wnt ligands: acts by interacting specifically with the disordered linker region of Wnt7, thereby conferring ligand selectivity for Wnt7. ADGRA2 is then required to deliver RECK-bound Wnt7 to frizzled by assembling a higher-order RECK-ADGRA2-Fzd-LRP5-LRP6 complex. Also acts as a serine protease inhibitor: negatively regulates matrix metalloproteinase-9 (MMP9) by suppressing MMP9 secretion and by direct inhibition of its enzymatic activity. Also inhibits metalloproteinase activity of MMP2 and MMP14 (MT1-MMP).", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5B2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5B2#function" }, { "database": "UniProtKB", "id": "ARBA00058722", "url": "https://www.uniprot.org/uniprotkb/ARBA00058722#function" }, { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2#function" }, { "database": "UniProtKB", "id": "F1ST89", "url": "https://www.uniprot.org/uniprotkb/F1ST89#function" }, { "database": "UniProtKB", "id": "A0A287AGZ8", "url": "https://www.uniprot.org/uniprotkb/A0A287AGZ8#function" }, { "database": "UniProtKB", "id": "A0A287AU65", "url": "https://www.uniprot.org/uniprotkb/A0A287AU65#function" }, { "database": "UniProtKB", "id": "A0A5G2QRH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRH1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RECK", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2", "locus": { "chromosome": "1", "start_pos": 236898276, "end_pos": 236821414, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005338", "url": "https://www.ensembl.org/id/ENSSSCG00000005338" } ] } } ], "crossref": [ { "id": "ENSSSCG00000005338", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005338", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100519638", "url": "https://www.ncbi.nlm.nih.gov/gene/100519638", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GEVCDTQ", "url": "https://omabrowser.org/oma/group/GEVCDTQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QZJ2", "url": "https://www.orthodb.org/?gene=A0A5G2QZJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13487", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13487", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13487:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13487:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22955", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22955", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22961", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22961", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23298", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23298", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23332", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23332", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020921638", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921638", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AGZ8", "url": "https://www.uniprot.org/uniprotkb/A0A287AGZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AGZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AGZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AU65", "url": "https://www.uniprot.org/uniprotkb/A0A287AU65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AU65-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AU65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5B2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5B2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ST89", "url": "https://www.uniprot.org/uniprotkb/F1ST89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ST89-1", "url": "https://www.uniprot.org/uniprotkb/F1ST89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATVRASPRGTLLLLLAVAGVAEVIGSLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSESRLKHLLQRAPDYCPETMVEIWSCMNSSLPGVFKKSDGWVGLGCCELAITLECRQACKQASSKNDISRVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTLHPPPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQDFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFNNRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFISIPVLDIKKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLENCIPLDTYLRPSTLGNIVEEVTHPCNPNPCPAHELCEVNRKGCPAGDPCLPYSCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCIEMHCIDLQKSCIVGGKRKSHGTSFNIDCNICSCFAGNLVCSTRLCLSADSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCISKDPCNPNPCPKSQRCIPKPQVCLTTFDKFGCSQYECLPRQLTCDQVRDPVCDTNHMEHNNLCTLYQRGKSLLYKGPCQPFCRASEPVCGHNGETYSSVCAAYSDRVAVDYYGPCQAVGVLSEYSSVAECAAVKCPSLSATECKPIIPPGACCPLCAGMLRVLFDKEKLDTIAKVTNKKPITVLEILQRIRMHVSVPQCDVFGYFSIESEIVILITPVDHSPKALQIEACNKEAEKIESLINSDSPTLAAHVPLSALIISQVQVSSSIPSAAPRALPPCRSHLFLLSLGLTLHRVWTHN", "length": 971, "header": "tr|A0A5G2QZJ2-1|A0A5G2QZJ2_PIG Isoform 1 of Reversion-inducing cysteine-rich protein with Kazal motifs OS=Sus scrofa OX=9823 GN=RECK PE=1 SV=1 CANONICAL=A0A5G2QZJ2-1" }, "isoforms": [ { "isoform_ac": "A0A287AGZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2/entry#A0A287AGZ8-1", "sequence": { "sequence": "PKTMLRVVLIFNLGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTLHPPPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQDFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFNNRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFISIPVLDIKKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLENCIPLDTYLRPSTLGNIVEEVTHPCNPNPCPAHELCEVNRKGCPAGDPCLPYSCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCIEMHCIDLQKSCIVGGKRKSHGTSFNIDCNICSCFAGNLVCSTRLCLSADSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCISKDPCNPNPCPKSQRCIPKPQVCLTTFDKFGCSQYECLPRQLTCDQVRDPVCDTNHMEHNNLCTLYQRGKSLLYKGPCQPFCRASEPVCGHNGETYSSVCAAYSDRVAVDYYGPCQAVGVLSEYSSVAECAAVKCPSLSATECKPIIPPGACCPLCAGMLRVLFDKEKLDTIAKVTNKKPITVLEILQRIRMHVSVPQCDVFGYFSIESEIVILITPVDHSPKALQIEACNKEAEKIESLINSDSPTLAAHVPLSALIISQVQVSSSIPSAAPRALPPCRSHLFLLSLGLTLHRVWTHN", "length": 837, "header": "tr|A0A287AGZ8-1|A0A5G2QZJ2_PIG Computationally mapped isoform of Reversion-inducing cysteine-rich protein with Kazal motifs OS=Sus scrofa OX=9823 GN=RECK PE=1 SV=2 CANONICAL=A0A5G2QZJ2-1" }, "locus": { "chromosome": "1", "start_pos": 236896853, "end_pos": 236860577, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038337.2", "url": "https://www.ensembl.org/id/ENSSSCT00000038337.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043181.2", "url": "https://www.ensembl.org/id/ENSSSCP00000043181.2" } ] } }, { "isoform_ac": "A0A287AU65-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2/entry#A0A287AU65-1", "sequence": { "sequence": "MKDGTGKNALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTLHPPPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQDFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFNNRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFISIPVLDIKKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLENCIPLDTYLRPSTLGNIVEEVTHPCNPNPCPAHELCEVNRKGCPAGDPCLPYSCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCIEMHCIDLQKSCIVGGKRKSHGTSFNIDCNICSCFAGNLVCSTRLCLSADSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCISKDPCNPNPCPKSQRCIPKPQVCLTTFDKFGCSQYECLPRQLTCDQVRDPVCDTNHMEHNNLCTLYQRGKSLLYKGPCQPFCRASEPVCGHNGETYSSVCAAYSDRVAVDYYGPCQAVGVLSEYSSVAECAAVKCPSLSATECKPIIPPGACCPLCAGMLRVLFDKEKLDTIAKVTNKKPITVLEILQRIRMHVSVPQCDVFGYFSIESEIVILITPVDHSPKALQIEACNKEAEKIESLINSDSPTLAAHVPLSALIISQVQVSSSIPSAAPRALPPCRSHLFLLSLGLTLHRVWTHN", "length": 843, "header": "tr|A0A287AU65-1|A0A5G2QZJ2_PIG Computationally mapped isoform of Reversion-inducing cysteine-rich protein with Kazal motifs OS=Sus scrofa OX=9823 GN=RECK PE=1 SV=2 CANONICAL=A0A5G2QZJ2-1" }, "locus": { "chromosome": "1", "start_pos": 236896853, "end_pos": 236844644, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065419.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065419.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047459.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047459.2" } ] } }, { "isoform_ac": "A0A5G2QRH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2/entry#A0A5G2QRH1-1", "sequence": { "sequence": "MATVRASPRGTLLLLLAVAGVAEVIGSLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSESRLKHLLQRAPDYCPETMVEIWSCMNSSLPGVFKKSDGWVGLGCCELAITLECRQACKQASSKNDISRVCRKEYEVLGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTLHPPPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQDFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFNNRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFISIPVLDIKKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLENCIPLDTYLRPSTLGNIVEEVTHPCNPNPCPAHELCEVNRKGCPAGDPCLPYSCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCIEMHCIDLQKSCIVGGKRKSHGTSFNIDCNICSCFAGNLVCSTRLCLSADSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCISKDPCNPNPCPKSQRCIPKPQVCLTTFDKFGCSQYECLPRQLTCDQVRDPVCDTNHMEHNNLCTLYQRGKSLLYKGPCQPFCRASEPVCGHNGETYSSVCAAYSDRVAVDYYGPCQAVGVLSEYSSVAECAAVKCPSLSATECKPIIPPGACCPLCAGMLRVLFDKEKLDTIAKVTNKKPITVLEILQRIRMHVSVPQCDVFGYFSIESEIVILITPVDHSPKALQIEACNKEAEKIESLINSDSPTLAAHVPLSALIISQVQVSSSIPSAAPRALPPCRSHLFLLSLGLTLHRVWTHN", "length": 961, "header": "tr|A0A5G2QRH1-1|A0A5G2QZJ2_PIG Computationally mapped isoform of Reversion-inducing cysteine-rich protein with Kazal motifs OS=Sus scrofa OX=9823 GN=RECK PE=1 SV=1 CANONICAL=A0A5G2QZJ2-1" }, "locus": { "chromosome": "1", "start_pos": 236896853, "end_pos": 236821484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067536.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067536.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066657.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066657.1" } ] } }, { "isoform_ac": "A0A5G2QZJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2/entry#A0A5G2QZJ2-1", "sequence": { "sequence": "MATVRASPRGTLLLLLAVAGVAEVIGSLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSESRLKHLLQRAPDYCPETMVEIWSCMNSSLPGVFKKSDGWVGLGCCELAITLECRQACKQASSKNDISRVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTLHPPPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQDFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFNNRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFISIPVLDIKKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLENCIPLDTYLRPSTLGNIVEEVTHPCNPNPCPAHELCEVNRKGCPAGDPCLPYSCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCIEMHCIDLQKSCIVGGKRKSHGTSFNIDCNICSCFAGNLVCSTRLCLSADSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCISKDPCNPNPCPKSQRCIPKPQVCLTTFDKFGCSQYECLPRQLTCDQVRDPVCDTNHMEHNNLCTLYQRGKSLLYKGPCQPFCRASEPVCGHNGETYSSVCAAYSDRVAVDYYGPCQAVGVLSEYSSVAECAAVKCPSLSATECKPIIPPGACCPLCAGMLRVLFDKEKLDTIAKVTNKKPITVLEILQRIRMHVSVPQCDVFGYFSIESEIVILITPVDHSPKALQIEACNKEAEKIESLINSDSPTLAAHVPLSALIISQVQVSSSIPSAAPRALPPCRSHLFLLSLGLTLHRVWTHN", "length": 971, "header": "tr|A0A5G2QZJ2-1|A0A5G2QZJ2_PIG Isoform 1 of Reversion-inducing cysteine-rich protein with Kazal motifs OS=Sus scrofa OX=9823 GN=RECK PE=1 SV=1 CANONICAL=A0A5G2QZJ2-1" }, "locus": { "chromosome": "1", "start_pos": 236896853, "end_pos": 236821484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090334.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090334.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063660.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063660.1" } ] } }, { "isoform_ac": "A0A5G2R5B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2/entry#A0A5G2R5B2-1", "sequence": { "sequence": "MATVRASPRGTLLLLLAVAGVAEVIGSLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSESRLKHLLQRAPDYCPETMASSKNDISRVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTLHPPPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQDFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFNNRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFISIPVLDIKKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLENCIPLDTYLRPSTLGNIVEEVTHPCNPNPCPAHELCEVNRKGCPAGDPCLPYSCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCIEMHCIDLQKSCIVGGKRKSHGTSFNIDCNICSCFAGNLVCSTRLCLSADSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCISKDPCNPNPCPKSQRCIPKPQVCLTTFDKFGCSQYECLPRQLTCDQVRDPVCDTNHMEHNNLCTLYQRGKSLLYKGPCQPFCRASEPVCGHNGETYSSVCAAYSDRVAVDYYGPCQAVGVLSEYSSVAECAAVKCPSLSATECKPIIPPGACCPLCAGMLRVLFDKEKLDTIAKVTNKKPITVLEILQRIRMHVSVPQCDVFGYFSIESEIVILITPVDHSPKALQIEACNKEAEKIESLINSDSPTLAAHVPLSALIISQVQVSSSIPSAAPRALPPCRSHLFLLSLGLTLHRVWTHN", "length": 930, "header": "tr|A0A5G2R5B2-1|A0A5G2QZJ2_PIG Computationally mapped isoform of Reversion-inducing cysteine-rich protein with Kazal motifs OS=Sus scrofa OX=9823 GN=RECK PE=1 SV=1 CANONICAL=A0A5G2QZJ2-1" }, "locus": { "chromosome": "1", "start_pos": 236896853, "end_pos": 236821484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072232.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072232.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072277.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072277.1" } ] } }, { "isoform_ac": "F1ST89-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2/entry#F1ST89-1", "sequence": { "sequence": "MATVRASPRGTLLLLLAVAGVAEVIGSLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSESRLKHLLQRAPDYCPETMVEIWSCMNSSLPGVFKKSDGWVGLGCCELAITLECRQACKQASSKNDISRVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTLHPPPSTGLDGAKLHCCSKANTSTCRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFISIPVLDIKKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLENCIPLDTYLRPSTLGNIVEEVTHPCNPNPCPAHELCEVNRKGCPAGDPCLPYSCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCIEMHCIDLQKSCIVGGKRKSHGTSFNIDCNICSCFAGNLVCSTRLCLSADSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCISKDPCNPNPCPKSQRCIPKPQVCLTTFDKFGCSQYECLPRQLTCDQVRDPVCDTNHMEHNNLCTLYQRGKSLLYKGPCQPFCRASEPVCGHNGETYSSVCAAYSDRVAVDYYGPCQAVGVLSEYSSVAECAAVKCPSLSATECKPIIPPGACCPLCAGMLRVLFDKEKLDTIAKVTNKKPITVLEILQRIRMHVSVPQCDVFGYFSIESEIVILITPVDHSPKALQIEACNKEAEKIESLINSDSPTLAAHVPLSALIISQVQVSSSIPSAAPRALPPCRSHLFLLSLGLTLHRVWTHN", "length": 911, "header": "tr|F1ST89-1|A0A5G2QZJ2_PIG Computationally mapped isoform of Reversion-inducing cysteine-rich protein with Kazal motifs OS=Sus scrofa OX=9823 GN=RECK PE=1 SV=5 CANONICAL=A0A5G2QZJ2-1" }, "locus": { "chromosome": "1", "start_pos": 236896853, "end_pos": 236821484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005877.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005877.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005731.5", "url": "https://www.ensembl.org/id/ENSSSCP00000005731.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRH1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZRL0-1", "protein_name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "gene_name": "Reck", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASVRASARGALLLLLSAAGVAKVTGGLAPGSAGAVCCNHSKDNQMCRDVCEQIFSSKSESRLKHLLQRAPDYCPETMVEIWSCMNSSLPDLRLSPCLLFCSCSDMQNSSCLSPHCTGVFKKSDGWVGLGCCELAIGLECRQACKQASSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREFCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEEHACQSACRRILTSKKTEMEIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTVHPPPSTGLDGAKLHCCSKANTSVCRELCTKLYSMSWGNTQSWQEFDRICEYNPGEVSMLACLADVREPCQLGCTNLTYCTNFNNRPTELFRSCTAQSDQGAMSDMRLWEKGSIKMPFISIPVLDIRTCQPDLWKAVACSLQIKPCHRKSRGSIICKSDCVEILKKCGDQNKFPEAHTAESICEFLSPADDVENCIPLDTYLRPSALGNIIEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYSCVQGCKLGEASDFIVRQGALIQVPSSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFTIDCNVCSCFAGNLVCSTRLCLSEHSSDDDRRAFTGLPCNCADQFVPVCAQNGRTYPSACIARCVGLQDHQFEFGPCISKDPCNPNLCPKSQRCVPKPQVCLTTFDKFGCSQYECVPRQLTCDQARDPVCDTDHVEHSNLCTLYQRGKSLSYRGPCQPFCRTTEPVCGHNGETYSSVCAAYSDRVAVDYYGRCQAVGVLSEHSAVTECAAVKCPSLSAIGCKPIIPPGACCPLCAGMLRVLFDKEKLDTIAKVTNKKPITVLEILQKIRMHVSVPQCDVFGYLSIESEIVILIIPVDHYPKALQIEACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSLPSSAVVGRLPPVHSLPLFLSLGLTVHLLQTCP", "length": 999 }, "evidence": [ { "id": "A0A5G2QZJ2", "url": "https://omabrowser.org/oma/group/A0A5G2QZJ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XV82-1", "protein_name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "gene_name": "RECK", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAVAAWPWALFCLAAVPPLLSPGAAGLSCCYHAKDNLMCRDVCEQILSSKSDSRLKHLLQRAPEYCPESMGEVWGCINSSLPGVLKKSDGWVGLGCCELAIAVECRQACKQASSKNDILKVCRKEYEEVGQYVLKENGRGKNALFSCINRNEMGSICCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDYACQTACKRILMSMKTELEIVDGLIEGCKTMPLPQDPLWQCFLESSRSVHPGVTVHPPPSTGLDGAKLHCCSKANSSTCRELCTKLYSTSWGSSQSWQEFDRFCEYNAVEVSMLTCLADVREPCQLGCRNLSYCTNFNNRPTELFRSCNSQSDQGAMNDMKLWEKGSIKMPFINIPVLDINKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDHNKFPEGHTAESICELLSPTDDLENCIPLDTYLSPSSLGNIVEDVTHPCNPNPCAANQLCEVNRKGCQSGELCLPYLCVPGCKLGEASDFIVRQGTLIQVPSSAGDVGCYKICTCGHTGLLENCVEMHCVDLQKSCIVGGQKKSHGTSFNIDCNVCSCFAGNLICSTRQCLTEHSSEDERQKFTGLPCNCVDQFVPVCGQNGRTYPSACIARCVGLQDNQFEFGSCISKDPCNPNPCSKNQRCIPKKQVCLTSFGKFECSQHECVPRQLNCDQTQDPVCDTDSVEYNNVCTLYQKGKNLAYRGPCQPFCKSVEPVCGHNGETYSSVCAAYSDRVAVDYYGHCQAVGVLSDYGFHTECAFVKCPQLSATGCKPVIAPGACCPLCAGMLRILYDKDKLDNFARVTNKKPITVLDILEKLRLHVSVPQCDVFGYLSIESEIVILIIPVDQKPKPLQIEACNKEAEKIESLINSDSPTLASHVPLSALIASQVQVSFSISSPSVKVGPVLHCLFISFSFTLLKLMDYI", "length": 977 }, "evidence": [ { "id": "A0A5G2QZJ2", "url": "https://omabrowser.org/oma/group/A0A5G2QZJ2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BCI6-1", "protein_name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "gene_name": "RECK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATVRASPRGALLLLLTVARVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSESRLKHLLQRAPDYCPETMVDIWSCMNSSLPGVFKKSDGWVGLGCCELAITLECRQACKQASSKNDISRVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPRLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQSACKRILMSKKTEMEIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTLHPPPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQEFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFNNRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFISIPVLDIKKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLENCIPLDTYLRPSSLGNIVEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYSCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCIEMHCIDLQKSCIVGGKRKSHGTSFNVDCNICSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCISKDPCTPNPCPKNQRCIPKPQVCLTTFDKFGCSQYECLPRQLTCDQVRDPVCDTNHMEHSNLCTLYQRGKSLLYKGPCQPFCRAPELVCGHNGETYSSVCAAYSDRVAIDYYGPCQAVGVLSEYSSVAECAAVKCPSLSVTECKPIIPPGACCPLCAGMLRVLFDKEKLDTIAKVTNKKPITVLEILQKVRMHVSVPQCDVFGYFSIESEIVILIIPVDHYPKALQIEACNKEAEKIESLINSDSPTLAAHVPLSALVISQVQVSSSMPSAAPSARPPHHSCLFLLSLGLTFHRVWRHN", "length": 971 }, "evidence": [ { "id": "A0A5G2QZJ2", "url": "https://omabrowser.org/oma/group/A0A5G2QZJ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O95980-1", "protein_name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "gene_name": "RECK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSESRLKHLLQRAPDYCPETMVEIWNCMNSSLPGVFKKSDGWVGLGCCELAIALECRQACKQASSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTVHPPPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQEFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFNNRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFINIPVLDIKKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLKNCIPLDTYLRPSTLGNIVEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPLCAGMLRVLFDKEKLDTIAKVTNKKPITVLEILQKIRMHVSVPQCDVFGYFSIESEIVILIIPVDHYPKALQIEACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSVPSAGVRARPSCHSLLLPLSLGLALHLLWTYN", "length": 971 }, "evidence": [ { "id": "A0A5G2QZJ2", "url": "https://omabrowser.org/oma/group/A0A5G2QZJ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VUJ2-1", "protein_name": "Reversion-inducing-cysteine-rich protein with kazal motifs, isoform A", "gene_name": "Reck", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLSGWEILLFLLPFGVVSAVRQLEENQSIKNDHHHSVERQVRRRNNKSNASVDHHRHAPSSGSKKNSRSHSVSLDSDDYDWLDADTSEAIDSSEVTAVESIRSPGESYDIFTCCNQVFGSCRTACENLSLVEFATGTGGDNRDELHRYCQLHQVEFWTCVNQTFDAITRGADWSGRRCCQFGVLPHCRNVCATSTRSPVQNCRRSDEQTLYDCLERQEAADQCCGQARTSECLEACRAVFEPANDNHDHVDINGACGDRNADVIQCVNNHTDMTPLANAEQYIPCCEYSSKEHCRHTCRNLLHQNATLMERSEVIFGRLEAAGCGSPLPQLPFWQCFLTVTGKLYVPGGSGRAGGSLAQGRISGQGGSLAEPNHLGMDAAKRQCCEQASSHKCRRLCNQIFTSNWWDARSSFENECMDQPGERELRRCIESVDAPCELGCQGLSFCSNFNNRPTELFRSCTPEHDAAAREDWQLLQQRGTVRVLGQELFIKNTSRCAPDKWRALVCALQLKPCTRVGLFNGICSEDCHELLDECLDWTLQHQRPKDICSRLKEKDDDDSPLPCISLESYLKPGDASPEEFQGITSPCAQKPCNGSEVCILQRGGNQGYSCIPGCNLGQDSKLFVPFGSYVRLGKSNLHKKLEVGQFPLAEHIVCSCGLQGRLEQCQPLPSYMHAHCTLPGARSYRHGSSFYLECNLCSCFAGEITCTKQQCRLPGFVDSGYTSLPCNCPAHYVPVCGSNGNTYPSACVAKCHLPEGDYVYGACNARNACQAAPPNSCPSGTQCLDSRKVCLASMQRPCLQYVCVNATASNCSTFHQGEVCDSQGRTYPNACALLKANPQGQVAYWSACQSSRFNTSPSPVCGINGVTYKSSYAARAEYVLVDYVGRCREVGLLVSDMGRRCRTVKCPAPVSKHCRLIVPPGACCPLCAGGAFRIIYSRKQFDRAMYGLRAQSSTLLTLQGVLQQLDGLVQVSECQLTGFLTMEVGIFVAIVPSSSIKRPTHLQLEACAREAEKISSLINAQSPRITTNLALSCLTVSHLLEPTPNGATSYGPHAIWILPLLLLVSRVIIA", "length": 1071 }, "evidence": [ { "id": "A0A5G2QZJ2", "url": "https://omabrowser.org/oma/group/A0A5G2QZJ2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z0J1-1", "protein_name": "Reversion-inducing cysteine-rich protein with Kazal motifs", "gene_name": "Reck", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASVRASPRSALLLLLAAAGVAEVTGGLAPGSAGAVCCNHSKDNQMCRDVCEQIFSSKSESRLKHLLQRAPDYCPETMVEIWSCMNSSLPGVFKKSDGWVGLGCCELAIGLECRQACKQASSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREFCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTVHPPPSTGLDGAKLHCCSKANTSTCRELCTKLYSMSWGNTQSWQEFDRICEYNPVEVSMLTCLADVREPCQLGCTNLTYCTNFNNRPTELFRSCTAQSDQGAMSDMKLWEKGSIKMPFISIPVLDIKTCQPEMWKAVACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEEHTAESICEFLSPADDLESCIPLDTYLRPSALGNIIEEVTHPCNPNPCPANELCEVNRKGCPSADPCLPYSCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFTIDCNVCSCFAGNLVCSTRLCLSEHSSDDDRRTFTGLPCNCADQFVPVCAQNGRTYPSACIARCVGLQDHQFEFGPCISKNPCNPNLCPKSQRCVPKPQVCLTTFDKFGCSQYECVPRQLTCDQARDPVCDTDHMEHSNLCTLYQRGKSLSYRGPCQPFCRAKEPVCGHNGETYSSVCAAYSDRVAVDYYGPCQAVGVLSEYSAVAECAAVKCPSLSAIGCKPIIPPGACCPLCAGMLRVLFDKEKLDTIAKVTSKKPITVVEILQKVRMHVSVPQCDVFGYLSIESEIVILIIPVDHYPKALQIEACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSLPSSAVVGRPLFHSLLLLLSLGLTVHLLWTRP", "length": 971 }, "evidence": [ { "id": "A0A5G2QZJ2", "url": "https://omabrowser.org/oma/group/A0A5G2QZJ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "metalloendopeptidase inhibitor activity", "id": "GO:0008191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008191", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "coreceptor activity", "id": "GO:0015026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015026", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "endopeptidase inhibitor activity", "id": "GO:0004866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004866", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "Wnt-protein binding", "id": "GO:0017147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017147", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "Wnt signalosome", "id": "GO:1990909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990909", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "regulation of extracellular matrix organization", "id": "GO:1903053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903053", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "blood vessel maturation", "id": "GO:0001955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001955", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "regulation of angiogenesis", "id": "GO:0045765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045765", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "regulation of establishment of blood-brain barrier", "id": "GO:0090210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090210", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" }, { "name": "negative regulation of extracellular matrix disassembly", "id": "GO:0010716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010716", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZJ2" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 627, "end_pos": 673, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1Z5-1", "uniprot_ac": "A0A5G2R1Z5", "uniprot_id": "A0A5G2R1Z5_PIG", "mass": { "chemical_mass": 55055.0, "monoisotopic_mass": 55055.0 }, "refseq": { "ac": "NP_001230322", "name": "heat shock 70 kDa protein 14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230322" }, "gene_names": [ { "name": "HSPA14", "type": "recommended", "evidence": [ { "id": "A0A5G2R1Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5" } ] }, { "name": "HSPA14", "type": "synonym", "evidence": [ { "id": "NP_001230322", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230322" } ] } ], "protein_names": [ { "name": "Heat shock 70 kDa protein 14", "type": "recommended", "evidence": [ { "id": "A0A5G2R1Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5/entry#names_and_taxonomy" } ] }, { "name": "heat shock 70 kDa protein 14", "type": "synonym", "evidence": [ { "id": "NP_001230322", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230322" } ] } ], "function": [ { "annotation": "Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "F1RTY7", "url": "https://www.uniprot.org/uniprotkb/F1RTY7#function" }, { "database": "UniProtKB", "id": "ARBA00024825", "url": "https://www.uniprot.org/uniprotkb/ARBA00024825#function" }, { "database": "UniProtKB", "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5#function" }, { "database": "UniProtKB", "id": "A0A5G2R6H4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H4#function" }, { "database": "UniProtKB", "id": "A0A287AKR7", "url": "https://www.uniprot.org/uniprotkb/A0A287AKR7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HSPA14", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5", "locus": { "chromosome": "10", "start_pos": 46904311, "end_pos": 46935280, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011051", "url": "https://www.ensembl.org/id/ENSSSCG00000011051" } ] } } ], "crossref": [ { "id": "A0A5G2R1Z5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1Z5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011051", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011051", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10238", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10238", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100510924", "url": "https://www.ncbi.nlm.nih.gov/gene/100510924", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100510924", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100510924", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DQVLMDH", "url": "https://omabrowser.org/oma/group/DQVLMDH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R1Z5", "url": "https://www.orthodb.org/?gene=A0A5G2R1Z5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19375", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19375", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3371453", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230322", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230322", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AKR7", "url": "https://www.uniprot.org/uniprotkb/A0A287AKR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AKR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AKR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6H4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTY7", "url": "https://www.uniprot.org/uniprotkb/F1RTY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTY7-1", "url": "https://www.uniprot.org/uniprotkb/F1RTY7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAVVAYTENEEVVGLAAKQSRIRNISNTVMKVKQILGRSSDDPQAQKYISESKCLVIEKNGKLRYEIDTGEEMKFVNPEDVARLIFSKMKETAHSVLGPDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSISVMQVNSGIYRVLSTNTDNNIGGTHFTETLAQYLASEFQRSFKHDVRGNARAMMKLMNSADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIRGLLEQSGFTADDINKVVLCGGSSRIPRLQQMIKELFPAVELLNSIPPDEVIPIGAAIEAGILIGKENLLVEDSLKIECSAKDILVKGVDESGANSFRVLFPSGTPLPARRQHMLQAPGSISSVCLELYESDGKNSAKEENKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 509, "header": "tr|A0A5G2R1Z5-1|A0A5G2R1Z5_PIG Isoform 1 of Heat shock 70 kDa protein 14 OS=Sus scrofa OX=9823 GN=HSPA14 PE=1 SV=1 CANONICAL=A0A5G2R1Z5-1" }, "isoforms": [ { "isoform_ac": "A0A287AKR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5/entry#A0A287AKR7-1", "sequence": { "sequence": "MAAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAVVAYTENEEVVGLAAKQSRIRNISNTVMKVKQILGRSSDDPQAQKYISESKCLVIEKNGKLRYEIDTGEEMKFVNPEDVARLIFSKMKETAHSVLGPDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKRSFKHDVRGNARAMMKLMNSADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIRGLLEQSGFTADDINKVVLCGGSSRIPRLQQMIKELFPAVELLNSIPPDEVIPIGAAIEAGILIGKENLLVEDSLKIECSAKDILVKGVDESGANSFRVLFPSGTPLPARRQHMLQAPGSISSVCLELYESDGKNSAKEENKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 455, "header": "tr|A0A287AKR7-1|A0A5G2R1Z5_PIG Computationally mapped isoform of Heat shock 70 kDa protein 14 OS=Sus scrofa OX=9823 GN=HSPA14 PE=1 SV=1 CANONICAL=A0A5G2R1Z5-1" }, "locus": { "chromosome": "10", "start_pos": 46935212, "end_pos": 46908304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037425.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037425.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044485.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044485.1" } ] } }, { "isoform_ac": "A0A5G2R1Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5/entry#A0A5G2R1Z5-1", "sequence": { "sequence": "MAAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAVVAYTENEEVVGLAAKQSRIRNISNTVMKVKQILGRSSDDPQAQKYISESKCLVIEKNGKLRYEIDTGEEMKFVNPEDVARLIFSKMKETAHSVLGPDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSISVMQVNSGIYRVLSTNTDNNIGGTHFTETLAQYLASEFQRSFKHDVRGNARAMMKLMNSADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIRGLLEQSGFTADDINKVVLCGGSSRIPRLQQMIKELFPAVELLNSIPPDEVIPIGAAIEAGILIGKENLLVEDSLKIECSAKDILVKGVDESGANSFRVLFPSGTPLPARRQHMLQAPGSISSVCLELYESDGKNSAKEENKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 509, "header": "tr|A0A5G2R1Z5-1|A0A5G2R1Z5_PIG Isoform 1 of Heat shock 70 kDa protein 14 OS=Sus scrofa OX=9823 GN=HSPA14 PE=1 SV=1 CANONICAL=A0A5G2R1Z5-1" }, "locus": { "chromosome": "10", "start_pos": 46935212, "end_pos": 46908304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084861.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084861.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071129.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071129.1" } ] } }, { "isoform_ac": "A0A5G2R6H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5/entry#A0A5G2R6H4-1", "sequence": { "sequence": "MAAIGVHLGCTSACVAVYKVVGLAAKQSRIRNISNTVMKVKQILGRSSDDPQAQKYISESKCLVIEKNGKLRYEIDTGEEMKFVNPEDVARLIFSKMKETAHSVLGPDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSISVMQVNSGIYRVLSTNTDNNIGGTHFTETLAQYLASEFQRSFKHDVRGNARAMMKLMNSADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIRGLLEQSGFTADDINKVVLCGGSSRIPRLQQMIKELFPAVELLNSIPPDEVIPIGAAIEAGILIGKENLLVEDSLKIECSAKDILVKGVDESGANSFRVLFPSGTPLPARRQHMLQAPGSISSVCLELYESDGKNSAKEENKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 482, "header": "tr|A0A5G2R6H4-1|A0A5G2R6H4_PIG Computationally mapped isoform of Heat shock 70 kDa protein 14 OS=Sus scrofa OX=9823 GN=HSPA14 PE=1 SV=2 CANONICAL=A0A5G2R1Z5-1" }, "locus": { "chromosome": "10", "start_pos": 46935212, "end_pos": 46908304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077717.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077717.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071940.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071940.2" } ] } }, { "isoform_ac": "F1RTY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5/entry#F1RTY7-1", "sequence": { "sequence": "MAAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAVVAYTENEEVVGLAAKQSRIRNISNTVMKVKQILGRSSDDPQAQKYISESKCLVIEKNGKLRYEIDTGEEMKFVNPEDVARLIFSKMKETAHSVLGPDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSISVMQVNSGIYRVLSTNTDNNIGGTHFTETLAQYLASEFQRSFKHDVRGNARAMMKLMNSADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIRGLLEQSGFTADDINKVVLCGGSSRIPRLQQMIKENLLVEDSLKIECSAKDILVKGVDESGANSFRVLFPSGTPLPARRQHMLQAPGSISSVCLELYESDGKNSAKEENKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 477, "header": "tr|F1RTY7-1|A0A5G2R1Z5_PIG Computationally mapped isoform of Heat shock 70 kDa protein 14 OS=Sus scrofa OX=9823 GN=HSPA14 PE=1 SV=3 CANONICAL=A0A5G2R1Z5-1" }, "locus": { "chromosome": "10", "start_pos": 46935212, "end_pos": 46908304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024833.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024833.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020003.3", "url": "https://www.ensembl.org/id/ENSSSCP00000020003.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTY7", "url": "https://www.uniprot.org/uniprotkb/F1RTY7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100510924", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100510924", "resource": "KEGG Pathway" }, { "id": "R-SSC-3371453", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "resource": "Reactome", "description": "Regulation of HSF1-mediated heat shock response" } ], "orthologs": [ { "uniprot_canonical_ac": "Q2YDD0-1", "protein_name": "Heat shock 70 kDa protein 14", "gene_name": "HSPA14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAIVAYSKNEEVVGLAAKQSRIRNISNTVMKVKQILGRSSDDPQSRKYITESKCLVIEKNGKLLYEIDTGEEKKFVSPEDVARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKSALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSISVMEVNSGIYRVLSTNTDNNIGGTHFTETLAQYLASEFQRSFRHDVRGNARAMMKLMNGADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIREVLEQSGFTADDINKVVLCGGSSRIPRLQQMIRDLFPAVELLNSIPPDEVIPIGAAIEAGILIGKESLSVEDALQIECSAKDILVKGVDESGANSFKVLFPSGTPLPARRQHTLQAPGSISSVCLELYESEGKNSAKVENKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 509 }, "evidence": [ { "id": "A0A5G2R1Z5", "url": "https://omabrowser.org/oma/group/A0A5G2R1Z5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99M31-1", "protein_name": "Heat shock 70 kDa protein 14", "gene_name": "Hspa14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAIVAYSEREQVVGLAAKQSRIRHVSSTVVKVKQILGRSSADPQAQKYISESKCLVIEKNGKLRYEIDTGEETKLVNPEDVARLIFSKMKETAHSVLGSDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDHPTGKSNVLVFKLGGTSLSLSVMEVNSGMYRVLSTNTSDNIGGAHFTDTLAQYLASEFQRLFKHDVRGNARAMMKLMNSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCTEAIRELLRQTGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVDLLNSIPPDEVIPIGAAIEAGILVGKESTSGDDSVMIECSAKDILVKGVDESGADRFTVLFPSGTPLPARRQHTLQAPGRVSSVCLELYESEGKNSAKEEAKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQDTGKCEAITVEVAS", "length": 509 }, "evidence": [ { "id": "A0A5G2R1Z5", "url": "https://omabrowser.org/oma/group/A0A5G2R1Z5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5" } ], "pmid": "" }, { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein refolding", "id": "GO:0042026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042026", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1Z5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 509, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1Z5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1Z5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 294, "end_pos": 296 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1M7-1", "uniprot_ac": "A0A5G2R1M7", "uniprot_id": "A0A5G2R1M7_PIG", "mass": { "chemical_mass": 48937.0, "monoisotopic_mass": 48937.0 }, "refseq": { "ac": "XP_020931850", "name": "cyclin-dependent kinase 15 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931850" }, "gene_names": [ { "name": "CDK15", "type": "recommended", "evidence": [ { "id": "A0A5G2R1M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7" } ] }, { "name": "CDK15", "type": "synonym", "evidence": [ { "id": "XP_020931850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931850" } ] } ], "protein_names": [ { "name": "cyclin-dependent kinase", "type": "recommended", "evidence": [ { "id": "A0A5G2R1M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.22", "type": "synonym", "evidence": [ { "id": "A0A5G2R1M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7/entry#names_and_taxonomy" } ] }, { "name": "cyclin-dependent kinase 15 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_020931850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931850" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1M7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CDK15", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7", "locus": { "chromosome": "15", "start_pos": 105506114, "end_pos": 105401165, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000022296", "url": "https://www.ensembl.org/id/ENSSSCG00000022296" } ] } } ], "crossref": [ { "id": "A0A5G2R1M7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1M7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000022296", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022296", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07870", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07870", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513315", "url": "https://www.ncbi.nlm.nih.gov/gene/100513315", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NPEWFLM", "url": "https://omabrowser.org/oma/group/NPEWFLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056:SF159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020931850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931850", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AL35", "url": "https://www.uniprot.org/uniprotkb/A0A287AL35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AL35-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AL35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BRW2", "url": "https://www.uniprot.org/uniprotkb/A0A287BRW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BRW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BRW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1M7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQELCAKTLQPGCSCHRCWEGGDAHSGQRSAPVTVEAAMELADLKEASCSMTSFHPRGPQSVHARKFKNKRPRSNSDSFQEEHLRQSFQWTKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYVHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVVGVPTEDTWPGVSKLPNYNPEWFPLPKPPSLQDVWHRLCRAPEAEDLASQMLKGFPRDRVSAQEALVHDYFSVLPAQLHQLPDEESLFTVSGVRLKPEMCDLLASYRKGHHPAEFSKCW", "length": 435, "header": "tr|A0A5G2R1M7-1|A0A5G2R1M7_PIG Isoform 1 of cyclin-dependent kinase OS=Sus scrofa OX=9823 GN=CDK15 PE=3 SV=1 CANONICAL=A0A5G2R1M7-1" }, "isoforms": [ { "isoform_ac": "A0A287AL35-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7/entry#A0A287AL35-1", "sequence": { "sequence": "MTSFHPRGPQSVHARKFKNKRPRSNSDSFQEEHLRQSFQWTKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYVHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVVGVPTEDTWPGVSKLPNYNPEWFPLPKPPSLQDVWHRLCRAPEAEDLASQMLKGFPRDRVSAQEALVHDYFSVLPAQLHQLPDEESLFTVSGVRLKPEMCDLLASYRKGHHPAEFSKCW", "length": 384, "header": "tr|A0A287AL35-1|A0A5G2R1M7_PIG Computationally mapped isoform of cyclin-dependent kinase OS=Sus scrofa OX=9823 GN=CDK15 PE=3 SV=1 CANONICAL=A0A5G2R1M7-1" }, "locus": { "chromosome": "15", "start_pos": 105502175, "end_pos": 105419349, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039539.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039539.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044737.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044737.1" } ] } }, { "isoform_ac": "A0A287BRW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7/entry#A0A287BRW2-1", "sequence": { "sequence": "MGQELCAKTLQPGCSCHRCWEGGDAHSGQRSAPVTVEAAMELADLKEASCSMTSFHPRGPQSVHARKFKNKRPRSNSDSFQEEHLRQSFQWTKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYVHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVVGVPTEDTWPGVSKLPNYNPEWFPLPKPPSLQDVWHRLCRAPEAEDLASQMLKGFPRDRVSAQEALVHDYFSVLPAQLHQLPDAQ", "length": 401, "header": "tr|A0A287BRW2-1|A0A287BRW2_PIG Computationally mapped isoform of cyclin-dependent kinase OS=Sus scrofa OX=9823 GN=CDK15 PE=3 SV=2 CANONICAL=A0A5G2R1M7-1" }, "locus": { "chromosome": "15", "start_pos": 105499203, "end_pos": 105418475, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059063.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059063.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059173.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059173.2" } ] } }, { "isoform_ac": "A0A5G2R1M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7/entry#A0A5G2R1M7-1", "sequence": { "sequence": "MGQELCAKTLQPGCSCHRCWEGGDAHSGQRSAPVTVEAAMELADLKEASCSMTSFHPRGPQSVHARKFKNKRPRSNSDSFQEEHLRQSFQWTKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYVHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVVGVPTEDTWPGVSKLPNYNPEWFPLPKPPSLQDVWHRLCRAPEAEDLASQMLKGFPRDRVSAQEALVHDYFSVLPAQLHQLPDEESLFTVSGVRLKPEMCDLLASYRKGHHPAEFSKCW", "length": 435, "header": "tr|A0A5G2R1M7-1|A0A5G2R1M7_PIG Isoform 1 of cyclin-dependent kinase OS=Sus scrofa OX=9823 GN=CDK15 PE=3 SV=1 CANONICAL=A0A5G2R1M7-1" }, "locus": { "chromosome": "15", "start_pos": 105502175, "end_pos": 105418475, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073664.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073664.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071086.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071086.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AL35", "url": "https://www.uniprot.org/uniprotkb/A0A287AL35" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A604-1", "protein_name": "Cyclin dependent kinase 15", "gene_name": "CDK15", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLCVSAGSARCGSCCSEGRGSQRGRGLQHAEAASTEELRDVTRAALPVPSQQPQHFHTLQSRRCRMWRPWTYNDHFKEQDVVESFKWQRQGIPFGAATSYVHLKKLCEGSSATVYKGISRINGQLVALKVISLETEEGVPFTAIREASLLKHLKHANIVLLHDIIQTKETLTFVLEYMHTDLAQYMAQHPGGLHPCNVMLFMFQLLRGLAYIHRQHILHRDLKPQNLLISCLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDVLLGATDYSSDLDIWSAGCVFVEMVQGQPVFAGTSSAPEQLEKIWTVLGVPTEDTWPGLSKLPKYKPELTASRRPQRLRVICDRLSRAPAAEDLASRMLTAFPPGRISAQDALLHGFFSPLPPQLYQVPPEQSVLTVPAVRLQPEICDLFTSYRKGRLSQGSSKFW", "length": 432 }, "evidence": [ { "id": "A0A5G2R1M7", "url": "https://omabrowser.org/oma/group/A0A5G2R1M7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7FC43-1", "protein_name": "cyclin-dependent kinase", "gene_name": "Cdk15", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGQELCAKRQPGCSCYHRSERGEAHSCQRSQPGSTEAAAFELTDIKGATCSLSSFHPRGLQGPGDQKLESKRPRSNSDSFQEENLRQGLPWQKKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIVHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPKPQSLQIVWSRLGGVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSVLPSQLYQLPDEESLFAVSGVKLKPEMCDLSASYRKGHYLAGFNKCW", "length": 436 }, "evidence": [ { "id": "A0A5G2R1M7", "url": "https://omabrowser.org/oma/group/A0A5G2R1M7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0R7D0-1", "protein_name": "cyclin-dependent kinase", "gene_name": "Cdk15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQELCAKSRQPGCSCYHRSEGGEAHSCQRSQPGSTSEPAVFELTDLKEASCSSASFHPRGLQAARVQKLESKRPRSNSDSFQEENLRQGVPWKKSFPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIVHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQRVLHRDLKPQNLLLSHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPPPEPQSLQTVWNRLGGVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSVLPSQLYQLPDEESLFAVSGVELKPEMCDLSASYRKGHLLAGVNKCW", "length": 437 }, "evidence": [ { "id": "A0A5G2R1M7", "url": "https://omabrowser.org/oma/group/A0A5G2R1M7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3V3A1-1", "protein_name": "Cyclin-dependent kinase 15", "gene_name": "Cdk15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQELCAKRLQPGCSCYHRSEGGEAHSCQRSQPGSTEPAVFELTEASSSTASFHPRGLEAASAQKLKSKRPRSNSDSFQEENLRQGLPWKKSLPFGAASSYLNLEKLGEGSYAKVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIVHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQRVLHRDLKPQNLLLSHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPPPKPQSLQIVWDRLGGVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSVLPSQLYQLPDEESLFAVSGVKLKPEMCDLSASYRKRHHLVGVNKCW", "length": 433 }, "evidence": [ { "id": "A0A5G2R1M7", "url": "https://omabrowser.org/oma/group/A0A5G2R1M7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96Q40-1", "protein_name": "Cyclin-dependent kinase 15", "gene_name": "CDK15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQELCAKTVQPGCSCYHCSEGGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRLKPEMCDLLASYQKGHHPAQFSKCW", "length": 435 }, "evidence": [ { "id": "A0A5G2R1M7", "url": "https://omabrowser.org/oma/group/A0A5G2R1M7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1M7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1M7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030332", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1M7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1M7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1M7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1M7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1M7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of cell cycle phase transition", "id": "GO:1901987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901987", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1M7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1M7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 435, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1M7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1M7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M7" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 103, "end_pos": 387, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3E7-1", "uniprot_ac": "A0A5G2R3E7", "uniprot_id": "A0A5G2R3E7_PIG", "mass": { "chemical_mass": 56795.0, "monoisotopic_mass": 56795.0 }, "refseq": {}, "gene_names": [ { "name": "TTC29", "type": "recommended", "evidence": [ { "id": "A0A5G2R3E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 29", "type": "recommended", "evidence": [ { "id": "A0A5G2R3E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Axonemal protein which is implicated in axonemal and/or peri-axonemal structure assembly and regulates flagellum assembly and beating and therefore sperm motility.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AQJ3", "url": "https://www.uniprot.org/uniprotkb/A0A287AQJ3#function" }, { "database": "UniProtKB", "id": "ARBA00044739", "url": "https://www.uniprot.org/uniprotkb/ARBA00044739#function" }, { "database": "UniProtKB", "id": "A0A5G2R3E7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3E7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TTC29", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7", "locus": { "chromosome": "8", "start_pos": 81982760, "end_pos": 81746489, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040272", "url": "https://www.ensembl.org/id/ENSSSCG00000040272" } ] } } ], "crossref": [ { "id": "A0A5G2R3E7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3E7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000040272", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000040272", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100627237", "url": "https://www.ncbi.nlm.nih.gov/gene/100627237", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100627237", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627237", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QLAWMSG", "url": "https://omabrowser.org/oma/group/QLAWMSG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287AQJ3", "url": "https://www.orthodb.org/?gene=A0A287AQJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46630", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46630", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46630:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46630:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AQJ3", "url": "https://www.uniprot.org/uniprotkb/A0A287AQJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AQJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3E7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATLPPLPMTRPKLTALARQKLPCSPRTIPRSQLIKEKDDIDHYLEVNFKGLSKEEVAAYRNSYKKNICVDMLRDGYHKSFTELFALMEKWDAQREAARLSSLLWVQRPLEEQPDKLDHFYHYLTRAEAAERKEYFEEVYNNLYALACYFNNSEDKWVRNHFYERCFKIAQLIKVDGGKKEAEAHAHMGLLFEEEGQLLEAAEHYEAFHQLTQGRIWTDETGRFLNLLACESLLRTYRLLSDKMLENKEYKQAIRILIKASEIAKAGNDKKMEGEASYYLGLAHLAAGEYETALAVLNTYGKISADLDDDLSLGRAYEATAKVLQSQGQMTEAIQYLKKVVNIARNNFQSLDFVRASTMLGDIFNEKGSYHKASEYFQQAFDTTAELTNVPLMDETKVHYGIAKAHQMMLTVNTYIESADLTSLDYLLSWKESRSDIAPLDYAPLQPKPGCLGLPVRLEIFREIPRARGNFFFTATLETTSRRQENRQTIIKN", "length": 493, "header": "tr|A0A5G2R3E7-1|A0A5G2R3E7_PIG Isoform 1 of Tetratricopeptide repeat protein 29 OS=Sus scrofa OX=9823 GN=TTC29 PE=4 SV=2 CANONICAL=A0A5G2R3E7-1" }, "isoforms": [ { "isoform_ac": "A0A287AQJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7/entry#A0A287AQJ3-1", "sequence": { "sequence": "MATLPPLPMTRPKLTALARQKLPCSPRTIPRSQLIKEKDDIDHYLEVNFKGLSKEEVAAYRNSYKKNICVDMLRDGYHKSFTELFALMEKWDAQREAARLSSLLWVQRPLEEQPDKLDHFYHYLTRAEAAERKEYFEEVYNNLYALACYFNNSEDKWVRNHFYERCFKIAQLIKVDGGKKEAEAHAHMGLLFEEEGQLLEAAEHYEAFHQLTQGRIWTDETGRFLNLLACESLLRTYRLLSDKMLENKEYKQAIRILIKASEIAKAGNDKKMEGEASYYLGLAHLAAGEYETALAVLNTYGKISADLDDDLSLGRAYEATAKVLQSQGQMTEAIQYLKKVVNIARNNFQSLDFVRASTMLGDIFNEKGSYHKASEYFQQAFDTTAELTNVPLMDETKVHYGIAKAHQMMLTVNTYIESADLTSLDYLLSWKESRSDIAPDPVVGGSRRSTMEGLYQTSEYLEEEHSG", "length": 467, "header": "tr|A0A287AQJ3-1|A0A5G2R3E7_PIG Computationally mapped isoform of Tetratricopeptide repeat protein 29 OS=Sus scrofa OX=9823 GN=TTC29 PE=4 SV=1 CANONICAL=A0A5G2R3E7-1" }, "locus": { "chromosome": "8", "start_pos": 81981160, "end_pos": 81754683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045074.2", "url": "https://www.ensembl.org/id/ENSSSCT00000045074.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046313.1", "url": "https://www.ensembl.org/id/ENSSSCP00000046313.1" } ] } }, { "isoform_ac": "A0A5G2R3E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7/entry#A0A5G2R3E7-1", "sequence": { "sequence": "MATLPPLPMTRPKLTALARQKLPCSPRTIPRSQLIKEKDDIDHYLEVNFKGLSKEEVAAYRNSYKKNICVDMLRDGYHKSFTELFALMEKWDAQREAARLSSLLWVQRPLEEQPDKLDHFYHYLTRAEAAERKEYFEEVYNNLYALACYFNNSEDKWVRNHFYERCFKIAQLIKVDGGKKEAEAHAHMGLLFEEEGQLLEAAEHYEAFHQLTQGRIWTDETGRFLNLLACESLLRTYRLLSDKMLENKEYKQAIRILIKASEIAKAGNDKKMEGEASYYLGLAHLAAGEYETALAVLNTYGKISADLDDDLSLGRAYEATAKVLQSQGQMTEAIQYLKKVVNIARNNFQSLDFVRASTMLGDIFNEKGSYHKASEYFQQAFDTTAELTNVPLMDETKVHYGIAKAHQMMLTVNTYIESADLTSLDYLLSWKESRSDIAPLDYAPLQPKPGCLGLPVRLEIFREIPRARGNFFFTATLETTSRRQENRQTIIKN", "length": 493, "header": "tr|A0A5G2R3E7-1|A0A5G2R3E7_PIG Isoform 1 of Tetratricopeptide repeat protein 29 OS=Sus scrofa OX=9823 GN=TTC29 PE=4 SV=2 CANONICAL=A0A5G2R3E7-1" }, "locus": { "chromosome": "8", "start_pos": 81968402, "end_pos": 81754683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082142.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082142.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071723.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071723.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AQJ3", "url": "https://www.uniprot.org/uniprotkb/A0A287AQJ3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100627237", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627237", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6AYP3-1", "protein_name": "Tetratricopeptide repeat protein 29", "gene_name": "Ttc29", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATFPPLSMTRTKLAVLARQKLPCSSKSIPRAQLIKEKDDIDYYLEQNIKGLSKEEVAAHRNSYKKSICVDMLRDGFHKSFTELFSLMEQWDKLREAAQARSLFWLQRPLEDQPDKLDNFYHYLTKAEAAERKGYYEEVYNNLYALACYFDNSEDKWVRNHFYERCFKIAQLIKVDGGKKEAEAEAHMGLLYEEEGELLKAAEHYEAFHELTQGRLWKDATGQFLNLIACESLVRTYRLLSDRMLQNRDYKQAIKILIKASEIAREGNDRSMEGEASYYLGLAHLASGEYETALSVLDRYSEISTSLDDELSLGRAYEAMAKVLQSQGEMTEAIKYLEKFVVIARNNFKSLDVIQACTMLGDIYNEKGQYNKASDYFQQAFSTAMEVTKTTLMDETKVHYGIARAHQMMLTMNGYIESADMNSLNCLLSWKETRTQVEYDPILGEARKATEDNIYQFPDAQEETRRSPENQ", "length": 471 }, "evidence": [ { "id": "A0A5G2R3E7", "url": "https://omabrowser.org/oma/group/A0A5G2R3E7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80VM3-1", "protein_name": "Tetratricopeptide repeat protein 29", "gene_name": "Ttc29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATFPPLPMTHTRLAILARQKLPCSSKKIPRAQLIKEKEDIDYYLEQNFKGLSKEEVAAHRNSYKKSICVDMLRDGFHKSFTELFALMEQWDKLPEAAKAQSLFWQQRPLEDQPDKLDNFYHYLTRAEAAERKGYYEEVYNNLYALACYFDNSEDKWVRNHFYERCFNIAQLIKADGGKKEAEAESHMGLLFEEEGELLKAAEHYEAFHELTHGRLWKDGTGQLLNLVACESLVRTYRLLSDRMLENKDYKQAIKILIKASEIAREGNDRSMEGEASYYLGLAHLASGEYETALTVLNRYSEISTSLDDDHGLGRAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLDMIRACTMLGDIYNEKGQYSKASEYFQQAFSTAMELMKTALMDETKVHYGIARAHQMMLAMKGYIESADSNGLNCLLSWKETRTQIEYDPILGESRRATEDNIYQLPDAEEETRRSPENQ", "length": 471 }, "evidence": [ { "id": "A0A5G2R3E7", "url": "https://omabrowser.org/oma/group/A0A5G2R3E7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NA56-1", "protein_name": "Tetratricopeptide repeat protein 29", "gene_name": "TTC29", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTLPPLPMTRPKLTALARQKLPCSSRKIPRSQLIKEKDDIDHYLEVNFKGLSKEEVAAYRNSYKKNICVDMLRDGYHKSFTELFALMERWDALREAARVRSLFWLQKPLEEQPDKLDYLYHYLTRAEDAERKESFEDVHNNLYALACYFNNSEDKWVRNHFYERCFKIAQLIKIDCGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMMLTVNNYIESADLTSLNYLLSWKESRGNIEPDPVTEEFRGSTVEAVSQNSERLEELSRFPGDQKNET", "length": 475 }, "evidence": [ { "id": "A0A5G2R3E7", "url": "https://omabrowser.org/oma/group/A0A5G2R3E7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3E7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3E7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3E7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3E7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3E7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3E7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R3E7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 493, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R3E7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3E7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0W2-1", "uniprot_ac": "A0A5G2R0W2", "uniprot_id": "A0A5G2R0W2_PIG", "mass": { "chemical_mass": 62651.0, "monoisotopic_mass": 62651.0 }, "refseq": {}, "gene_names": [ { "name": "RNF220", "type": "recommended", "evidence": [ { "id": "A0A5G2R0W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RNF220", "type": "recommended", "evidence": [ { "id": "A0A5G2R0W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A5G2R0W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2/entry#names_and_taxonomy" } ] }, { "name": "RING finger protein 220", "type": "synonym", "evidence": [ { "id": "A0A5G2R0W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase RNF220", "type": "synonym", "evidence": [ { "id": "A0A5G2R0W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RNF220", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2", "locus": { "chromosome": "6", "start_pos": 166666138, "end_pos": 166910646, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037341", "url": "https://www.ensembl.org/id/ENSSSCG00000037341" } ] } } ], "crossref": [ { "id": "A0A5G2R0W2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0W2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000037341", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037341", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16563", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16563", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13459", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13459", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13459:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13459:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AU87", "url": "https://www.uniprot.org/uniprotkb/A0A287AU87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AU87-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AU87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLHRAAFKMENSSYLPNPLASPALMVLASTAEASRDASIPCQQPRPFGVPVSVDKDVHIPFTNGSYTFASMYHRQGGVPGTFANRDFPPSLLHLHPQFAPPNLDCTPISMLNHSGVGAFRPFASAEDRESYQSAFTPAKRLKNCHDTESPHLRFSDADGKEYDFGTQLPSSSPGSLKVDDTGKKIFAVSGLISDREASSSPEDRNDRCKKKAAALFDSQAPICPICQVLLRPSELQEHMEQELEQLAQLPSSKNSLLKDAMAPGTPKSLLLSASIKREGESPTASPHSSATDDLHHSDRYQTFLRVRANRQTRLNARIGKMKRRKQDEGQREGSCMAEEDAVDIEHENSNRFEEYEWCGQKRIRATTLLEGGFRGSGFVMCSGKENPDSDADLDVDGDDTLEYGKPQYTEADVIPCTGEEPGEAKEREALRGAVLNGGPPSTRITPEFSKWASDEMPSTSNGESSKQEAMQKTCKNSDIEKITEDSAVTTFEALKARVRELERQLSRDRYKCLICMDSYSMPLTSIQCWHVHCEECWLRTLGAKKLCPQCNTITAPGDLRRIYL", "length": 565, "header": "tr|A0A5G2R0W2-1|A0A5G2R0W2_PIG Isoform 1 of E3 ubiquitin-protein ligase RNF220 OS=Sus scrofa OX=9823 GN=RNF220 PE=1 SV=1 CANONICAL=A0A5G2R0W2-1" }, "isoforms": [ { "isoform_ac": "A0A287AU87-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2/entry#A0A287AU87-1", "sequence": { "sequence": "LSHNQTPGSLLLSASIKREGESPTASPHSSATDDLHHSDRYQTFLRVRANRQTRLNARIGKMKRRKQDEGQVCPLCSRPLAGSEQELSRHVERCLSKREGSCMAEEDAVDIEHENSNRFEEYEWCGQKRIRATTLLEGGFRGSGFVMCSGKENPDSDADLDVDGDDTLEYGKPQYTEADVIPCTGEEPGEAKEREALRGAVLNGGPPSTRITPEFSKWASDEMPSTSNGESSKQEAMQKTCKNSDIEKITEDSAVTTFEALKARVRELERQLSRGTVTNASSAWTPIRCP", "length": 290, "header": "tr|A0A287AU87-1|A0A5G2R0W2_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase RNF220 OS=Sus scrofa OX=9823 GN=RNF220 PE=1 SV=2 CANONICAL=A0A5G2R0W2-1" }, "locus": { "chromosome": "6", "start_pos": 166690127, "end_pos": 166667898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037689.2", "url": "https://www.ensembl.org/id/ENSSSCT00000037689.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047484.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047484.2" } ] } }, { "isoform_ac": "A0A5G2R0W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2/entry#A0A5G2R0W2-1", "sequence": { "sequence": "MDLHRAAFKMENSSYLPNPLASPALMVLASTAEASRDASIPCQQPRPFGVPVSVDKDVHIPFTNGSYTFASMYHRQGGVPGTFANRDFPPSLLHLHPQFAPPNLDCTPISMLNHSGVGAFRPFASAEDRESYQSAFTPAKRLKNCHDTESPHLRFSDADGKEYDFGTQLPSSSPGSLKVDDTGKKIFAVSGLISDREASSSPEDRNDRCKKKAAALFDSQAPICPICQVLLRPSELQEHMEQELEQLAQLPSSKNSLLKDAMAPGTPKSLLLSASIKREGESPTASPHSSATDDLHHSDRYQTFLRVRANRQTRLNARIGKMKRRKQDEGQREGSCMAEEDAVDIEHENSNRFEEYEWCGQKRIRATTLLEGGFRGSGFVMCSGKENPDSDADLDVDGDDTLEYGKPQYTEADVIPCTGEEPGEAKEREALRGAVLNGGPPSTRITPEFSKWASDEMPSTSNGESSKQEAMQKTCKNSDIEKITEDSAVTTFEALKARVRELERQLSRDRYKCLICMDSYSMPLTSIQCWHVHCEECWLRTLGAKKLCPQCNTITAPGDLRRIYL", "length": 565, "header": "tr|A0A5G2R0W2-1|A0A5G2R0W2_PIG Isoform 1 of E3 ubiquitin-protein ligase RNF220 OS=Sus scrofa OX=9823 GN=RNF220 PE=1 SV=1 CANONICAL=A0A5G2R0W2-1" }, "locus": { "chromosome": "6", "start_pos": 166903889, "end_pos": 166667062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083299.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083299.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067851.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067851.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 284, "start_aa": "Thr", "end_pos": 284, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr284", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AU87", "url": "https://www.uniprot.org/uniprotkb/A0A287AU87" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" }, { "name": "nuclear lamina", "id": "GO:0005652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005652", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" }, { "name": "regulation of postsynaptic neurotransmitter receptor internalization", "id": "GO:0099149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099149", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0W2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983140" } ] }, { "id": "R-SSC-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983147" } ] }, { "id": "R-SSC-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983156" } ] }, { "id": "R-SSC-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0W2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 565, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0W2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0W2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0W2" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 513, "end_pos": 552, "start_aa": "Cys", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 284 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 12, "end_pos": 14 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R140-1", "uniprot_ac": "A0A5G2R140", "uniprot_id": "A0A5G2R140_PIG", "mass": { "chemical_mass": 33970.0, "monoisotopic_mass": 33970.0 }, "refseq": {}, "gene_names": [ { "name": "TRA2A", "type": "recommended", "evidence": [ { "id": "A0A5G2R140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" } ] } ], "protein_names": [ { "name": "Transformer-2 protein homolog alpha", "type": "recommended", "evidence": [ { "id": "A0A5G2R140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140/entry#names_and_taxonomy" } ] }, { "name": "Transformer-2 protein homolog A", "type": "synonym", "evidence": [ { "id": "A0A5G2R140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140#function" }, { "database": "UniProtKB", "id": "ARBA00056621", "url": "https://www.uniprot.org/uniprotkb/ARBA00056621#function" }, { "database": "UniProtKB", "id": "A0A288CG19", "url": "https://www.uniprot.org/uniprotkb/A0A288CG19#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TRA2A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140", "locus": { "chromosome": "9", "start_pos": 92294917, "end_pos": 92323794, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015387", "url": "https://www.ensembl.org/id/ENSSSCG00000015387" } ] } } ], "crossref": [ { "id": "A0A5G2R140", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R140", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015387", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015387", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12363", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12363", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A288CG19", "url": "https://www.uniprot.org/uniprotkb/A0A288CG19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A288CG19-1", "url": "https://www.uniprot.org/uniprotkb/A0A288CG19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R140-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGRRRDSYYDRGYDRGYDRYEDYDYRYRRRSPSPYYSRYRSRSRSRSYSPSRYTFALVAFLINGLF", "length": 294, "header": "tr|A0A5G2R140-1|A0A5G2R140_PIG Isoform 1 of Transformer-2 protein homolog alpha OS=Sus scrofa OX=9823 GN=TRA2A PE=1 SV=1 CANONICAL=A0A5G2R140-1" }, "isoforms": [ { "isoform_ac": "A0A288CG19-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140/entry#A0A288CG19-1", "sequence": { "sequence": "CKLKLNNILIQQANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGRRRDSYYDRGYDRGYDRYEDYDYRYRISLFIHSKCYHLQLLTPNSQSISLSPLRQPQVCSPCP", "length": 193, "header": "tr|A0A288CG19-1|A0A288CG19_PIG Computationally mapped isoform of Transformer-2 protein homolog alpha OS=Sus scrofa OX=9823 GN=TRA2A PE=3 SV=2 CANONICAL=A0A5G2R140-1" }, "locus": { "chromosome": "9", "start_pos": 92307464, "end_pos": 92301368, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016762.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016762.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016314.4", "url": "https://www.ensembl.org/id/ENSSSCP00000016314.4" } ] } }, { "isoform_ac": "A0A5G2R140-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140/entry#A0A5G2R140-1", "sequence": { "sequence": "MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGRRRDSYYDRGYDRGYDRYEDYDYRYRRRSPSPYYSRYRSRSRSRSYSPSRYTFALVAFLINGLF", "length": 294, "header": "tr|A0A5G2R140-1|A0A5G2R140_PIG Isoform 1 of Transformer-2 protein homolog alpha OS=Sus scrofa OX=9823 GN=TRA2A PE=1 SV=1 CANONICAL=A0A5G2R140-1" }, "locus": { "chromosome": "9", "start_pos": 92323585, "end_pos": 92300187, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084233.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084233.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070828.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070828.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 204, "start_aa": "Thr", "end_pos": 204, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr204", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 24, "start_aa": "Thr", "end_pos": 24, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr24", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R140-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 294, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R140-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R140" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R140" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 197, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 24, 204 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1A5-1", "uniprot_ac": "A0A5G2R1A5", "uniprot_id": "A0A5G2R1A5_PIG", "mass": { "chemical_mass": 11602.0, "monoisotopic_mass": 11602.0 }, "refseq": { "ac": "XP_003357183", "name": "mitochondrial import inner membrane translocase subunit Tim10 B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357183" }, "gene_names": [ { "name": "TIMM10B", "type": "recommended", "evidence": [ { "id": "A0A5G2R1A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5" } ] }, { "name": "TIMM10B", "type": "synonym", "evidence": [ { "id": "XP_003357183", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357183" } ] } ], "protein_names": [ { "name": "Mitochondrial import inner membrane translocase subunit", "type": "recommended", "evidence": [ { "id": "A0A5G2R1A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial import inner membrane translocase subunit Tim10 B", "type": "synonym", "evidence": [ { "id": "XP_003357183", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357183" } ] } ], "function": [ { "annotation": "Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5#function" }, { "database": "UniProtKB", "id": "ARBA00037309", "url": "https://www.uniprot.org/uniprotkb/ARBA00037309#function" } ] }, { "annotation": "Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5#function" }, { "database": "UniProtKB", "id": "RU367043", "url": "https://www.uniprot.org/uniprotkb/RU367043#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TIMM10B", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5", "locus": { "chromosome": "9", "start_pos": 3248159, "end_pos": 3250050, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037299", "url": "https://www.ensembl.org/id/ENSSSCG00000037299" } ] } } ], "crossref": [ { "id": "ENSSSCG00000037299", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037299", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100623727", "url": "https://www.ncbi.nlm.nih.gov/gene/100623727", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050673", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050673", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623727", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623727", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FNRCVDN", "url": "https://omabrowser.org/oma/group/FNRCVDN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R1A5", "url": "https://www.orthodb.org/?gene=A0A5G2R1A5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13172", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13172", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1268020", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1268020", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003357183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357183", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SGN1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SGN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SGN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SGN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQQQQQQQQLRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVQLMPALVQRRIADYEAASAVPGVAAEQPEASPSGS", "length": 103, "header": "tr|A0A5G2R1A5-1|A0A5G2R1A5_PIG Isoform 1 of Mitochondrial import inner membrane translocase subunit OS=Sus scrofa OX=9823 GN=TIMM10B PE=1 SV=1 CANONICAL=A0A5G2R1A5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SGN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5/entry#A0A4X1SGN1-1", "sequence": { "sequence": "MEQQQQQQQQLRNEACLHSCAGKLIHSNHRLMAAYVQLMPALVQRRIADYEAASAVPGVAAEQPEASPSGS", "length": 71, "header": "tr|A0A4X1SGN1-1|A0A4X1SGN1_PIG Computationally mapped isoform of Translocase of inner mitochondrial membrane 10B OS=Sus scrofa OX=9823 GN=TIMM10B PE=1 SV=1 CANONICAL=A0A5G2R1A5-1" }, "locus": { "chromosome": "9", "start_pos": 3249868, "end_pos": 3249163, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060390.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060390.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038069.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038069.2" } ] } }, { "isoform_ac": "A0A5G2R1A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5/entry#A0A5G2R1A5-1", "sequence": { "sequence": "MEQQQQQQQQLRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVQLMPALVQRRIADYEAASAVPGVAAEQPEASPSGS", "length": 103, "header": "tr|A0A5G2R1A5-1|A0A5G2R1A5_PIG Isoform 1 of Mitochondrial import inner membrane translocase subunit OS=Sus scrofa OX=9823 GN=TIMM10B PE=1 SV=1 CANONICAL=A0A5G2R1A5-1" }, "locus": { "chromosome": "9", "start_pos": 3249868, "end_pos": 3249163, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076013.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076013.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070893.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070893.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623727", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623727", "resource": "KEGG Pathway" }, { "id": "R-SSC-1268020", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1268020", "resource": "Reactome", "description": "Mitochondrial protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "G3IDF3-1", "protein_name": "Mitochondrial import inner membrane translocase subunit", "gene_name": "Timm10b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEQQQQQLRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVHLMPALVQRRIADYEAASAVPGVTAEQPRDSPSGS", "length": 100 }, "evidence": [ { "id": "A0A5G2R1A5", "url": "https://omabrowser.org/oma/group/A0A5G2R1A5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9R1B1-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim10 B", "gene_name": "Timm10b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHQQQQLRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVHLMPALVQRRMADYEAASAVPGVPAEQPRDSPSGS", "length": 100 }, "evidence": [ { "id": "A0A5G2R1A5", "url": "https://omabrowser.org/oma/group/A0A5G2R1A5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WV96-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim10 B", "gene_name": "Timm10b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQQQQQLRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVHLMPALVQRRIADYEAASAAPGIPAEQTRDSPSGS", "length": 100 }, "evidence": [ { "id": "A0A5G2R1A5", "url": "https://omabrowser.org/oma/group/A0A5G2R1A5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y0V3-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim10B", "gene_name": "Tim9b", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDSNLRNLKDFFTLYNKVTELCFSRCVDNLSQRDLGGHEDLCVDRCVTKFARFNQNMMKVYVDVQTTINAKRMEEMEENARKAEQQQREQEKERLKEAAATAVLTPVQPPVAGNLSM", "length": 117 }, "evidence": [ { "id": "A0A5G2R1A5", "url": "https://omabrowser.org/oma/group/A0A5G2R1A5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y5J6-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim10 B", "gene_name": "TIMM10B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERQQQQQQQLRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVQLMPALVQRRIADYEAASAVPGVAAEQPGVSPSGS", "length": 103 }, "evidence": [ { "id": "A0A5G2R1A5", "url": "https://omabrowser.org/oma/group/A0A5G2R1A5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial intermembrane space chaperone complex", "id": "GO:0042719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042719", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5" } ], "pmid": "" }, { "name": "TIM22 mitochondrial import inner membrane insertion complex", "id": "GO:0042721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042721", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5" } ], "pmid": "" }, { "name": "protein insertion into mitochondrial inner membrane", "id": "GO:0045039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045039", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5" } ], "pmid": "" }, { "name": "protein transporter activity", "id": "GO:0140318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140318", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A5" }, { "id": "PF02953", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02953" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tim10-like", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 68, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWN4-1", "uniprot_ac": "A0A5G2QWN4", "uniprot_id": "A0A5G2QWN4_PIG", "mass": { "chemical_mass": 20225.0, "monoisotopic_mass": 20225.0 }, "refseq": {}, "gene_names": [ { "name": "CETN3", "type": "recommended", "evidence": [ { "id": "A0A5G2QWN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ] } ], "protein_names": [ { "name": "Centrin 3", "type": "synonym", "evidence": [ { "id": "A0A5G2QWN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU6#function" }, { "database": "UniProtKB", "id": "ARBA00060271", "url": "https://www.uniprot.org/uniprotkb/ARBA00060271#function" } ] }, { "annotation": "Plays a fundamental role in microtubule-organizing center structure and function.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU6#function" }, { "database": "UniProtKB", "id": "ARBA00056666", "url": "https://www.uniprot.org/uniprotkb/ARBA00056666#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CETN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4", "locus": { "chromosome": "2", "start_pos": 97572449, "end_pos": 97593291, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014151", "url": "https://www.ensembl.org/id/ENSSSCG00000014151" } ] } } ], "crossref": [ { "id": "A0A5G2QWN4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWN4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014151", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014151", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "574052", "url": "https://www.ncbi.nlm.nih.gov/gene/574052", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:574052", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:574052", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EFFMIMK", "url": "https://omabrowser.org/oma/group/EFFMIMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TDU6", "url": "https://www.orthodb.org/?gene=A0A4X1TDU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23048:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23048:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1TBD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TBD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TBD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TBD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TDU6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TDU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLALRNELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADILKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINFSKTKLFSRFFANYLM", "length": 171, "header": "tr|A0A5G2QWN4-1|A0A5G2QWN4_PIG Isoform 1 of Centrin 3 OS=Sus scrofa OX=9823 GN=CETN3 PE=4 SV=1 CANONICAL=A0A5G2QWN4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TBD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4/entry#A0A4X1TBD7-1", "sequence": { "sequence": "MSLALRNELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADILKILKDYDREATGKITFEDFNEVGVYFNSLCNHQLLENYLTF", "length": 108, "header": "tr|A0A4X1TBD7-1|A0A4X1TBD7_PIG Computationally mapped isoform of Centrin 3 OS=Sus scrofa OX=9823 GN=CETN3 PE=4 SV=1 CANONICAL=A0A5G2QWN4-1" }, "locus": { "chromosome": "2", "start_pos": 97593198, "end_pos": 97589525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044902.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044902.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052309.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052309.2" } ] } }, { "isoform_ac": "A0A4X1TDU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4/entry#A0A4X1TDU6-1", "sequence": { "sequence": "MSLALRNELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADILKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI", "length": 167, "header": "tr|A0A4X1TDU6-1|A0A4X1TDU6_PIG Computationally mapped isoform of Centrin-3 OS=Sus scrofa OX=9823 GN=CETN3 PE=3 SV=1 CANONICAL=A0A5G2QWN4-1" }, "locus": { "chromosome": "2", "start_pos": 97593198, "end_pos": 97574370, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015458.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015458.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015048.3", "url": "https://www.ensembl.org/id/ENSSSCP00000015048.3" } ] } }, { "isoform_ac": "A0A5G2QWN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4/entry#A0A5G2QWN4-1", "sequence": { "sequence": "MSLALRNELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADILKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINFSKTKLFSRFFANYLM", "length": 171, "header": "tr|A0A5G2QWN4-1|A0A5G2QWN4_PIG Isoform 1 of Centrin 3 OS=Sus scrofa OX=9823 GN=CETN3 PE=4 SV=1 CANONICAL=A0A5G2QWN4-1" }, "locus": { "chromosome": "2", "start_pos": 97593198, "end_pos": 97582812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082250.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082250.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069276.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069276.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:574052", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:574052", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N547-1", "protein_name": "Centrin-3", "gene_name": "CETN3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLALRNDLVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI", "length": 167 }, "evidence": [ { "id": "A0A5G2QWN4", "url": "https://omabrowser.org/oma/group/A0A5G2QWN4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HL74-1", "protein_name": "Centrin-3", "gene_name": "Cetn3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLALRSELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDHAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI", "length": 167 }, "evidence": [ { "id": "A0A5G2QWN4", "url": "https://omabrowser.org/oma/group/A0A5G2QWN4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0RCW6-1", "protein_name": "Centrin-3", "gene_name": "Cetn3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RGGRASVPQRGQGGRGREAESGADEECRASDLGGPRLPQRRSPSEVSRGFPHASAGFGPGRLLPPESHRRARLSARVPWHAVLWASWVDLVSVTPSSHFRTSPLPIGSSPCPSTLKGAPGPRISLGGELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI", "length": 287 }, "evidence": [ { "id": "A0A5G2QWN4", "url": "https://omabrowser.org/oma/group/A0A5G2QWN4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15182-1", "protein_name": "Centrin-3", "gene_name": "CETN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLALRSELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI", "length": 167 }, "evidence": [ { "id": "A0A5G2QWN4", "url": "https://omabrowser.org/oma/group/A0A5G2QWN4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35648-1", "protein_name": "Centrin-3", "gene_name": "Cetn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLALRGELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI", "length": 167 }, "evidence": [ { "id": "A0A5G2QWN4", "url": "https://omabrowser.org/oma/group/A0A5G2QWN4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06704-1", "protein_name": "Cell division control protein 31", "gene_name": "CDC31", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSKNRSSLQSGPLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAICTDS", "length": 161 }, "evidence": [ { "id": "A0A5G2QWN4", "url": "https://omabrowser.org/oma/group/A0A5G2QWN4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" }, { "name": "G-protein beta/gamma-subunit complex binding", "id": "GO:0031683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031683", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" }, { "name": "nuclear pore nuclear basket", "id": "GO:0044615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" }, { "name": "transcription export complex 2", "id": "GO:0070390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070390", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" }, { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWN4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 171, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWN4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWN4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWN4" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 60, "start_aa": "Glu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 155, "end_pos": 157 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1L1-1", "uniprot_ac": "A0A5G2R1L1", "uniprot_id": "A0A5G2R1L1_PIG", "mass": { "chemical_mass": 42379.0, "monoisotopic_mass": 42379.0 }, "refseq": { "ac": "XP_003123896", "name": "geranylgeranyl transferase type-1 subunit beta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123896" }, "gene_names": [ { "name": "PGGT1B", "type": "recommended", "evidence": [ { "id": "A0A5G2R1L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1" } ] }, { "name": "PGGT1B", "type": "synonym", "evidence": [ { "id": "XP_003123896", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123896" } ] } ], "protein_names": [ { "name": "Geranylgeranyl transferase type-1 subunit beta", "type": "recommended", "evidence": [ { "id": "A0A5G2R1L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.59", "type": "synonym", "evidence": [ { "id": "A0A5G2R1L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1/entry#names_and_taxonomy" } ] }, { "name": "Geranylgeranyl transferase type I subunit beta", "type": "synonym", "evidence": [ { "id": "A0A5G2R1L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1/entry#names_and_taxonomy" } ] }, { "name": "Type I protein geranyl-geranyltransferase subunit beta", "type": "synonym", "evidence": [ { "id": "A0A5G2R1L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1/entry#names_and_taxonomy" } ] }, { "name": "geranylgeranyl transferase type-1 subunit beta", "type": "synonym", "evidence": [ { "id": "XP_003123896", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123896" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1L1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PGGT1B", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1", "locus": { "chromosome": "2", "start_pos": 119383387, "end_pos": 119440322, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014215", "url": "https://www.ensembl.org/id/ENSSSCG00000014215" } ] } } ], "crossref": [ { "id": "A0A5G2R1L1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1L1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014215", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014215", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02895", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02895", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100520066", "url": "https://www.ncbi.nlm.nih.gov/gene/100520066", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520066", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520066", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RWCLMRQ", "url": "https://omabrowser.org/oma/group/RWCLMRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R1L1", "url": "https://www.orthodb.org/?gene=A0A5G2R1L1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11774", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11774", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11774:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11774:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003123896", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123896", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21240", "url": "https://www.rhea-db.org/rhea/21240", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1U0P0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U0P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0P0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1L1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RLE8", "url": "https://www.uniprot.org/uniprotkb/F1RLE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RLE8-1", "url": "https://www.uniprot.org/uniprotkb/F1RLE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATEDERPAGSGDGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKPCSENVHIST", "length": 377, "header": "tr|A0A5G2R1L1-1|A0A5G2R1L1_PIG Isoform 1 of Geranylgeranyl transferase type-1 subunit beta OS=Sus scrofa OX=9823 GN=PGGT1B PE=3 SV=1 CANONICAL=A0A5G2R1L1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U0P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1/entry#A0A4X1U0P0-1", "sequence": { "sequence": "MAATEDERPAGSGDGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKPCSENVHIST", "length": 300, "header": "tr|A0A4X1U0P0-1|A0A4X1U0P0_PIG Computationally mapped isoform of Protein geranylgeranyltransferase type I subunit beta OS=Sus scrofa OX=9823 GN=PGGT1B PE=3 SV=1 CANONICAL=A0A5G2R1L1-1" }, "locus": { "chromosome": "2", "start_pos": 119440314, "end_pos": 119391145, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098118.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098118.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074694.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074694.1" } ] } }, { "isoform_ac": "A0A5G2R1L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1/entry#A0A5G2R1L1-1", "sequence": { "sequence": "MAATEDERPAGSGDGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKPCSENVHIST", "length": 377, "header": "tr|A0A5G2R1L1-1|A0A5G2R1L1_PIG Isoform 1 of Geranylgeranyl transferase type-1 subunit beta OS=Sus scrofa OX=9823 GN=PGGT1B PE=3 SV=1 CANONICAL=A0A5G2R1L1-1" }, "locus": { "chromosome": "2", "start_pos": 119440314, "end_pos": 119391145, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103857.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103857.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078423.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078423.1" } ] } }, { "isoform_ac": "F1RLE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1/entry#F1RLE8-1", "sequence": { "sequence": "MAATEDERPAGSGDGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKNPGTAHPNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKPCSENVHIST", "length": 351, "header": "tr|F1RLE8-1|A0A5G2R1L1_PIG Computationally mapped isoform of Geranylgeranyl transferase type-1 subunit beta OS=Sus scrofa OX=9823 GN=PGGT1B PE=3 SV=4 CANONICAL=A0A5G2R1L1-1" }, "locus": { "chromosome": "2", "start_pos": 119440314, "end_pos": 119391145, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015533.4", "url": "https://www.ensembl.org/id/ENSSSCT00000015533.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015121.4", "url": "https://www.ensembl.org/id/ENSSSCP00000015121.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RLE8", "url": "https://www.uniprot.org/uniprotkb/F1RLE8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520066", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520066", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O80642-1", "protein_name": "Geranylgeranyl transferase type-1 subunit beta", "gene_name": "GGB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSETAVSIDSDRSKSEEEDEEEYSPPVQSSPSANFEKDRHLMYLEMMYELLPYHYQSQEINRLTLAHFIISGLHFLGARDRVDKDVVAKWVLSFQAFPTNRVSLKDGEFYGFFGSRSSQFPIDENGDLKHNGSHLASTYCALAILKVIGHDLSTIDSKSLLISMINLQQDDGSFMPIHIGGETDLRFVYCAAAICYMLDSWSGMDKESAKNYILNCQSYDGGFGLIPGSESHGGATYCAIASLRLMGYIGVDLLSNDSSSSIIDPSLLLNWCLQRQANDGGFQGRTNKPSDTCYAFWIGAVLKLIGGDALIDKMALRKFLMSCQSKYGGFSKFPGQLPDLYHSYYGYTAFSLLEEQGLSPLCPELGLPLLAAPGI", "length": 375 }, "evidence": [ { "id": "A0A5G2R1L1", "url": "https://omabrowser.org/oma/group/A0A5G2R1L1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P53609-1", "protein_name": "Geranylgeranyl transferase type-1 subunit beta", "gene_name": "PGGT1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATEDERLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKAPGTAHPYDSGHIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAITYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLLDLHQSWKTKDSKQCSENVHIST", "length": 377 }, "evidence": [ { "id": "A0A5G2R1L1", "url": "https://omabrowser.org/oma/group/A0A5G2R1L1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P53610-1", "protein_name": "Geranylgeranyl transferase type-1 subunit beta", "gene_name": "Pggt1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS", "length": 377 }, "evidence": [ { "id": "A0A5G2R1L1", "url": "https://omabrowser.org/oma/group/A0A5G2R1L1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q24173-1", "protein_name": "Geranylgeranyl transferase type-1 subunit beta", "gene_name": "betaggt-I", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEDRTDTEPVLLSKHAKNLLRFLNLLPARMASHDNTRSTIVFFAVCGLDVLNSLHLVPPQLRQDIIDWIYGGLVVPRDNEKNCGGFMGCRAMVPKTEDAEILECMRNYQWGHLAMTYTSLAVLVTLGDDLSRLDRKSIVDGVAAVQKPEGSFSACIDGSEDDMRFVYCAATICYMLDYWGDVNKETMFQFITRSLRYDYGFSQELEGEAHGGTTFCALAALHLSGQLHRLDATTVERMKRWLIFRQMDGFQGRPNKPVDTCYSFWIGASLCILDGFELTDYARNREFILSTQDKLIGGFAKWPQATPDPFHTYLGLCGLAFTGEPGLSPVNPSLNMSMAAYAHLQHLHEQWRSADGRGDEDISVSSAFKQQLHLSKGVEATSTTTTSNSPLISAQ", "length": 395 }, "evidence": [ { "id": "A0A5G2R1L1", "url": "https://omabrowser.org/oma/group/A0A5G2R1L1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q55DA3-1", "protein_name": "Geranylgeranyl transferase type-1 subunit beta", "gene_name": "pggt1b", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGSCINEEKLAKFFQRSLNALPAPYTSGLPNHLSLIFFVVSGLDLLNKTDILEKEKQDIINWVYSRQILPSKDNPEINLENCGFRGYNFLGQEFCCDKSVHTSENGPLEYDLPSTPNTYCALLILRILGDDFSGVNKKAIIDSLRKRQRESDGAISGSPNVGDYDLRHLFSACAISFILDDWSAINKESAIDYIKSCLSYEFAFGQTPQQEAHGGPTYCAIASLSLLGRLDVLEPFKEQLTFWLVKKQITGFCGRTNKDPDTCYAFWIGASLMMIDRYDLIDFASINAFIGSAQHEAIGGVAKEPGQLPDVMHSYLSLVGLSFGNIPSIQQVIPCLNLSKRAAGKDWFEKLI", "length": 352 }, "evidence": [ { "id": "A0A5G2R1L1", "url": "https://omabrowser.org/oma/group/A0A5G2R1L1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5EAD5-1", "protein_name": "Geranylgeranyl transferase type-1 subunit beta", "gene_name": "PGGT1B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAATEDERPTGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAINYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSENVHIST", "length": 377 }, "evidence": [ { "id": "A0A5G2R1L1", "url": "https://omabrowser.org/oma/group/A0A5G2R1L1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BUY9-1", "protein_name": "Geranylgeranyl transferase type-1 subunit beta", "gene_name": "Pggt1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLSRCGFRGSSYLGIPFNPSKNPGAAHPYDSGHIAMTYTGLSCLIILGDDLGRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHIAT", "length": 377 }, "evidence": [ { "id": "A0A5G2R1L1", "url": "https://omabrowser.org/oma/group/A0A5G2R1L1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1L1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1" } ], "pmid": "" }, { "name": "protein prenyltransferase activity", "id": "GO:0008318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008318", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1L1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1" } ], "pmid": "" }, { "name": "CAAX-protein geranylgeranyltransferase activity", "id": "GO:0004662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004662", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1L1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "CAAX-protein geranylgeranyltransferase complex", "id": "GO:0005953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005953", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1L1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "CAAX-box protein maturation", "id": "GO:0080120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080120", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1L1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21240", "name": "", "equation": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "21240", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21240" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1L1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 377, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1L1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1L1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1L1" }, { "id": "PF00432", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00432" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Prenyltransferase alpha-alpha toroid", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 346, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 345, "end_pos": 347 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0D0-1", "uniprot_ac": "A0A5G2R0D0", "uniprot_id": "A0A5G2R0D0_PIG", "mass": { "chemical_mass": 18315.0, "monoisotopic_mass": 18315.0 }, "refseq": { "ac": "XP_003360356", "name": "mitochondrial import inner membrane translocase subunit Tim17-B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003360356" }, "gene_names": [ { "name": "TIMM17B", "type": "recommended", "evidence": [ { "id": "A0A5G2R0D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0D0" } ] }, { "name": "TIMM17B", "type": "synonym", "evidence": [ { "id": "XP_003360356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003360356" } ] } ], "protein_names": [ { "name": "Mitochondrial import inner membrane translocase subunit TIM17", "type": "recommended", "evidence": [ { "id": "A0A5G2R0D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0D0/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial import inner membrane translocase subunit Tim17-B", "type": "synonym", "evidence": [ { "id": "XP_003360356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003360356" } ] } ], "function": [ { "annotation": "Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VM89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VM89#function" }, { "database": "UniProtKB", "id": "ARBA00002959", "url": "https://www.uniprot.org/uniprotkb/ARBA00002959#function" }, { "database": "UniProtKB", "id": "A0A5G2R0D0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0D0#function" }, { "database": "UniProtKB", "id": "RU364008", "url": "https://www.uniprot.org/uniprotkb/RU364008#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0D0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0D0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TIMM17B", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0D0", "locus": { "chromosome": "X", "start_pos": 42970108, "end_pos": 42975955, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000022647", "url": "https://www.ensembl.org/id/ENSSSCG00000022647" } ] } } ], "crossref": [ { "id": "A0A5G2R0D0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0D0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000022647", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022647", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100621014", "url": "https://www.ncbi.nlm.nih.gov/gene/100621014", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621014", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621014", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FDCTFQY", "url": "https://omabrowser.org/oma/group/FDCTFQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R0D0", "url": "https://www.orthodb.org/?gene=A0A5G2R0D0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10485", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10485", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10485:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10485:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02466", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02466", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1268020", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1268020", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003360356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003360356", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1VM89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VM89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VM89-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VM89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0D0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0D0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIRHRLRGSVNAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSITSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQQFRNAPPFLEDPSQLPPKEGTPAPGYPSYQQYH", "length": 172, "header": "tr|A0A5G2R0D0-1|A0A5G2R0D0_PIG Isoform 1 of Mitochondrial import inner membrane translocase subunit TIM17 OS=Sus scrofa OX=9823 GN=TIMM17B PE=3 SV=2 CANONICAL=A0A5G2R0D0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1VM89-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0D0/entry#A0A4X1VM89-1", "sequence": { "sequence": "MIAVEPSLWVLSAVESSRPLRASAMPLSVSAPNPKEAFTDCSATLRSLHPIISITCGCLKLSGSPVPLFRICSSYTVNSERGIRHRLRGSVNAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSITSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQQFRNAPPFLEDPSQLPPKEGTPAPGYPSYQQYH", "length": 211, "header": "tr|A0A4X1VM89-1|A0A5G2R0D0_PIG Computationally mapped isoform of Mitochondrial import inner membrane translocase subunit TIM17 OS=Sus scrofa OX=9823 GN=TIMM17B PE=3 SV=1 CANONICAL=A0A5G2R0D0-1" }, "locus": { "chromosome": "X", "start_pos": 42974998, "end_pos": 42970873, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027760.4", "url": "https://www.ensembl.org/id/ENSSSCT00000027760.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028151.2", "url": "https://www.ensembl.org/id/ENSSSCP00000028151.2" } ] } }, { "isoform_ac": "A0A5G2R0D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0D0/entry#A0A5G2R0D0-1", "sequence": { "sequence": "MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIRHRLRGSVNAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSITSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQQFRNAPPFLEDPSQLPPKEGTPAPGYPSYQQYH", "length": 172, "header": "tr|A0A5G2R0D0-1|A0A5G2R0D0_PIG Isoform 1 of Mitochondrial import inner membrane translocase subunit TIM17 OS=Sus scrofa OX=9823 GN=TIMM17B PE=3 SV=2 CANONICAL=A0A5G2R0D0-1" }, "locus": { "chromosome": "X", "start_pos": 42975898, "end_pos": 42970873, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074074.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074074.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067656.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067656.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VM89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VM89" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621014", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621014", "resource": "KEGG Pathway" }, { "id": "R-SSC-1268020", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1268020", "resource": "Reactome", "description": "Mitochondrial protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8J8XD91-1", "protein_name": "Translocase of inner mitochondrial membrane 17b", "gene_name": "Timm17b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAVKGFRNAPVGIRHRFRGSINAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSITSGALTGAVLAARSECFQPLTPVLALFCLPFLSCVSFCLPGGPLAMVGSAMMGGILLALIEGVGILLTRYTAQQFRNAPPFLEDPNQLTPKEGAPAPGYPNYQQYH", "length": 199 }, "evidence": [ { "id": "A0A5G2R0D0", "url": "https://omabrowser.org/oma/group/A0A5G2R0D0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7GN11-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim17-B isoform X1", "gene_name": "Timm17b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEEYAREPWTGSPFIAQVGLQLVILLPHLPKHCAYSPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIRHRFRGSINAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSITSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQQFRNAPPFLEDPNQLTPKEGAPAPGYPNYQQYH", "length": 199 }, "evidence": [ { "id": "A0A5G2R0D0", "url": "https://omabrowser.org/oma/group/A0A5G2R0D0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A8WHN3-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim17-B", "gene_name": "timm17b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEEYAREPCPWRIVDDCGGAFTMGAIGGGVFQTVKGFRNAPVGVRHRLRGSANAVRVRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSITSGAMTGAILAARSGPLAMVGSAMMGGILLALIEGFGILLTRYTAQQFQNSSPIVEDPKQLPPKEEARGYGQYQ", "length": 167 }, "evidence": [ { "id": "A0A5G2R0D0", "url": "https://omabrowser.org/oma/group/A0A5G2R0D0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O60830-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim17-B", "gene_name": "TIMM17B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIRHRLRGSANAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSITSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQQFRNAPPFLEDPSQLPPKDGTPAPGYPSYQQYH", "length": 172 }, "evidence": [ { "id": "A0A5G2R0D0", "url": "https://omabrowser.org/oma/group/A0A5G2R0D0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P39515-1", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM17", "gene_name": "TIM17", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSADHSRDPCPIVILNDFGGAFAMGAIGGVVWHGIKGFRNSPLGERGSGAMSAIKARAPVLGGNFGVWGGLFSTFDCAVKAVRKREDPWNAIIAGFFTGGALAVRGGWRHTRNSSITCACLLGVIEGVGLMFQRYAAWQAKPMAPPLPEAPSSQPLQA", "length": 158 }, "evidence": [ { "id": "A0A5G2R0D0", "url": "https://omabrowser.org/oma/group/A0A5G2R0D0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7PLT4-1", "protein_name": "Translocase of the inner mitochondrial membrane 17b, isoform B", "gene_name": "Tim17b", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEEYAREPCPYRIVDDCGGAFAMGCIGGGVFQAIKGFRNAPSGLNRRLVGSIIAIKTRSPVIAGNFAVWGGMFSTIDCTLVHFRKKEDPWNSIISGAATGGILAARNGVPAMAGSAIIGGVLLALIEGVGILFTRISADQFKNPIPPAEDPVALGDPGRNFSFESASNRTQYQ", "length": 173 }, "evidence": [ { "id": "A0A5G2R0D0", "url": "https://omabrowser.org/oma/group/A0A5G2R0D0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z0V7-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim17-B", "gene_name": "Timm17b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIRHRFRGSVNAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSISSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQQFRNAPPFLEDPSQLTPKEGSPAPGYPNYQQYH", "length": 172 }, "evidence": [ { "id": "A0A5G2R0D0", "url": "https://omabrowser.org/oma/group/A0A5G2R0D0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "TIM23 mitochondrial import inner membrane translocase complex", "id": "GO:0005744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005744", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0D0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0D0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0D0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0D0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein transmembrane transporter activity", "id": "GO:0008320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008320", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0D0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0D0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0D0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 172, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0D0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0D0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1W8-1", "uniprot_ac": "A0A5G2R1W8", "uniprot_id": "A0A5G2R1W8_PIG", "mass": { "chemical_mass": 49272.0, "monoisotopic_mass": 49272.0 }, "refseq": { "ac": "XP_013842827", "name": "evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842827" }, "gene_names": [ { "name": "ECSIT", "type": "recommended", "evidence": [ { "id": "A0A5G2R1W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ] }, { "name": "ECSIT", "type": "synonym", "evidence": [ { "id": "XP_013842827", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842827" } ] } ], "protein_names": [ { "name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A5G2R1W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8/entry#names_and_taxonomy" } ] }, { "name": "evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013842827", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842827" } ] } ], "function": [ { "annotation": "Adapter protein that plays a role in different signaling pathways including TLRs and IL-1 pathways or innate antiviral induction signaling. Plays a role in the activation of NF-kappa-B by forming a signal complex with TRAF6 and TAK1/MAP3K7 to activate TAK1/MAP3K7 leading to activation of IKKs. Once ubiquitinated, interacts with the dissociated RELA and NFKB1 proteins and translocates to the nucleus where it induces NF-kappa-B-dependent gene expression. Plays a role in innate antiviral immune response by bridging the pattern recognition receptors RIGI and MDA5/IFIT1 to the MAVS complex at the mitochondrion. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QHH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHH8#function" }, { "database": "UniProtKB", "id": "ARBA00045816", "url": "https://www.uniprot.org/uniprotkb/ARBA00045816#function" }, { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8#function" }, { "database": "UniProtKB", "id": "F1SA28", "url": "https://www.uniprot.org/uniprotkb/F1SA28#function" } ] }, { "annotation": "As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QHH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHH8#function" }, { "database": "UniProtKB", "id": "ARBA00029396", "url": "https://www.uniprot.org/uniprotkb/ARBA00029396#function" }, { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8#function" }, { "database": "UniProtKB", "id": "F1SA28", "url": "https://www.uniprot.org/uniprotkb/F1SA28#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ECSIT", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8", "locus": { "chromosome": "2", "start_pos": 70154843, "end_pos": 70170744, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013615", "url": "https://www.ensembl.org/id/ENSSSCG00000013615" } ] } } ], "crossref": [ { "id": "A0A5G2R1W8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1W8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013615", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013615", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100519412", "url": "https://www.ncbi.nlm.nih.gov/gene/100519412", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519412", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519412", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPFHIWL", "url": "https://omabrowser.org/oma/group/GPFHIWL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R1W8", "url": "https://www.orthodb.org/?gene=A0A5G2R1W8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13113:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13113:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06239", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06239", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14784", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14784", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-166058", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-166058", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975138", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975138", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975871", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975871", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013842827", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842827", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QHH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SA28", "url": "https://www.uniprot.org/uniprotkb/F1SA28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SA28-1", "url": "https://www.uniprot.org/uniprotkb/F1SA28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWAQAVLLARSLSRGWGGICSTALTGAPFSQVPLQAAHGLHCSTAMHTFDSSLVPHPPKPPRRPIKALALHEELFRKAPDGTREKASFVQAIQDFAQYNVHKRGHVDFIYLALRKMREYGVERDLAVYNLLLDIFPKEVFRPRSIFQTIFYHYPRQQECGIAVLEQMENHGVMPNKETEFLLIQIFGRKSYPMLKYVRMKLWFTRFRNINPFPLPRDLPQDPVDLARLALRHMEPDLSARVTVYQMSLPEDSKDAVDPTEPHIVGIQSPDQQAALACHDPARPIFVEGPFSLWLRDKCVYYHILRADLLPPEERKVEEIPEEWSLYYPMQLDLAYERSGWDDYKFNINEVEEGPVFAICMAGAHDQATLAKWIQGLQETNPALARIPVVFRLAGSAGELLASSSGPEGSSPPPSEGQEEEDDNQQRQQQGQS", "length": 433, "header": "tr|A0A5G2R1W8-1|A0A5G2R1W8_PIG Isoform 1 of Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial OS=Sus scrofa OX=9823 GN=ECSIT PE=1 SV=2 CANONICAL=A0A5G2R1W8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QHH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8/entry#A0A5G2QHH8-1", "sequence": { "sequence": "MSWAQAVLLARSLSRGWGGICSTALTGAPFSQMSLPEDSKDAVDPTEPHIVGIQSPDQQAALACHDPARPIFVEGPFSLWLRDKCVYYHILRADLLPPEERKVEEIPEEWSLYYPMQLDLAYERSGWDDYKFNINEVEEGPVFAICMAGAHDQATLAKWIQGLQETNPALARIPVVFRLAGSAGELLASSSGPEGSSPPPSEGQEEEDDNQQRQQQGQS", "length": 219, "header": "tr|A0A5G2QHH8-1|A0A5G2R1W8_PIG Computationally mapped isoform of Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial OS=Sus scrofa OX=9823 GN=ECSIT PE=1 SV=2 CANONICAL=A0A5G2R1W8-1" }, "locus": { "chromosome": "2", "start_pos": 70162913, "end_pos": 70154983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082900.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082900.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063305.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063305.2" } ] } }, { "isoform_ac": "A0A5G2R1W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8/entry#A0A5G2R1W8-1", "sequence": { "sequence": "MSWAQAVLLARSLSRGWGGICSTALTGAPFSQVPLQAAHGLHCSTAMHTFDSSLVPHPPKPPRRPIKALALHEELFRKAPDGTREKASFVQAIQDFAQYNVHKRGHVDFIYLALRKMREYGVERDLAVYNLLLDIFPKEVFRPRSIFQTIFYHYPRQQECGIAVLEQMENHGVMPNKETEFLLIQIFGRKSYPMLKYVRMKLWFTRFRNINPFPLPRDLPQDPVDLARLALRHMEPDLSARVTVYQMSLPEDSKDAVDPTEPHIVGIQSPDQQAALACHDPARPIFVEGPFSLWLRDKCVYYHILRADLLPPEERKVEEIPEEWSLYYPMQLDLAYERSGWDDYKFNINEVEEGPVFAICMAGAHDQATLAKWIQGLQETNPALARIPVVFRLAGSAGELLASSSGPEGSSPPPSEGQEEEDDNQQRQQQGQS", "length": 433, "header": "tr|A0A5G2R1W8-1|A0A5G2R1W8_PIG Isoform 1 of Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial OS=Sus scrofa OX=9823 GN=ECSIT PE=1 SV=2 CANONICAL=A0A5G2R1W8-1" }, "locus": { "chromosome": "2", "start_pos": 70162913, "end_pos": 70154984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075722.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075722.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064528.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064528.2" } ] } }, { "isoform_ac": "F1SA28-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8/entry#F1SA28-1", "sequence": { "sequence": "MSWAQAVLLARSLSRGWGGICSTALTGAPFSQYHSSQQCQILNPLMEARVRTHILMDTSQVPLQAAHGLHCSTAMHTFDSSLVPHPPKPPRRPIKALALHEELFRKAPDGTREKASFVQAIQDFAQYNVHKRGHVDFIYLALRKMREYGVERDLAVYNLLLDIFPKEVFRPRSIFQTIFYHYPRQQECGIAVLEQMENHGVMPNKETEFLLIQIFGRKSYPMLKYVRMKLWFTRFRNINPFPLPRDLPQDPVDLARLALRHMEPDLSARVTVYQMSLPEDSKDAVDPTEPHIVGIQSPDQQAALACHDPARPIFVEGPFSLWLRDKCVYYHILRADLLPPEERKVEEIPEEWSLYYPMQLDLAYERSGWDDYKFNINEVEEGPVFAICMAGAHDQATLAKWIQGLQETNPALARIPVVFRLAGSAGELLASSSGPEGSSPPPSEGQEEEDDNQQRQQQGQS", "length": 461, "header": "tr|F1SA28-1|F1SA28_PIG Computationally mapped isoform of Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial OS=Sus scrofa OX=9823 GN=ECSIT PE=1 SV=4 CANONICAL=A0A5G2R1W8-1" }, "locus": { "chromosome": "2", "start_pos": 70162913, "end_pos": 70154984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014870.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014870.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014469.4", "url": "https://www.ensembl.org/id/ENSSSCP00000014469.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 260, "start_aa": "Thr", "end_pos": 260, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr260", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QHH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHH8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519412", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519412", "resource": "KEGG Pathway" }, { "id": "R-SSC-166058", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-166058", "resource": "Reactome", "description": "MyD88:MAL(TIRAP) cascade initiated on plasma membrane" }, { "id": "R-SSC-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799198", "resource": "Reactome", "description": "Complex I biogenesis" }, { "id": "R-SSC-975138", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975138", "resource": "Reactome", "description": "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" }, { "id": "R-SSC-975871", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975871", "resource": "Reactome", "description": "MyD88 cascade initiated on plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GY04-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "Ecsit", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGWVQASLLVRGLSRGWGSICSTALSRAATTQVSLQAPRGLHCSAVIHKDDVSLVPRPPEPQRKPIKVPVLHEELFTPSATGEKDKASFLRALRSFEEHSVRKRGHVDFIYLALRKMPEFGVERDLSVYNLLLDVFPKEIFRPRNIIQRIFVHYPRQQECGISVLEQMERYAQVDLELLCCGAKPVLGLLIYVSSRPECWDYSSFICTGVMPNTETEFLLTQIFGRTSYPMLKFLRMKLWLTRFKNINPYPVPRDLPQDPLDLAKLSLRRMEPDLSAKVTVYQMSLPSDSTGTDPIQPHIVGIQSPDQQAALARHNPSKPVFVEGPFPLWLRNKCVYYHILRADLPLPEEEKVEEIPEEWNLYYPMKLDLEYSRSGWDNYEFDLDEVTEGPVFAMCMAGAHDQATLVKWIQGLQETNPILAQVPVVFRLARSTGELLTTSRLEEQSPPHGSPRDQEEDALQAQPQQG", "length": 467 }, "evidence": [ { "id": "A0A5G2R1W8", "url": "https://omabrowser.org/oma/group/A0A5G2R1W8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q08CK1-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ecsit", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSASHHLLRLQCVRCVSHFLGTPVRQVILPGRAHLQTPGSQHIYVQLLRPFHRSAVCSTDRQNRTDIEKLVEDETHHKDKTLVTHDDIFDRAAGDSKTKVEFNRVVDVFKSKDIRRRGHVEFIYAALKKMPEFGVECDVTVYNKLLDVFPKEVFVPQNFIQRMFNHYPRQQECGVQVLEQMENYGVMPNIETKVLLVQIFGEKSHPIRKFQRIMYWFPKFKHTNPYPVPHVLPSDPVDLAQFSLTRIAADLDAKITIYQYPSTDITETGEEITRPHIVGIQSPDQRSLLAKHNPCKPVFVEGPYPLWLRQKCVHYYLLRADPIPPEEKVEEEIDPEMICPEQSLFFPQRVELDLKVDMGDDHSFNVDEVEEGAVYAMCMAGQGDQATLSQWISGLQETCPILGQIPTVFRLESGPRELQTSTDDHQRPEQEAETDQIIEDDEEPRHSRGVKQ", "length": 452 }, "evidence": [ { "id": "A0A5G2R1W8", "url": "https://omabrowser.org/oma/group/A0A5G2R1W8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3SX05-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSWAQAILLARGASRGWGGICSTALTGAPFSQVPPQAPRGLRCSAAAHNPDSSLVPHPPEPPRRPVKALAVHEELFRPALDGARNKANFVRAVQNFTEYNVHKRGHVDFIYLALRKMREYGVERDLSVYNLLLDIFPKEVFRPRNIFHSIFLHYPRQQECGIAVLEQMENHGVMPNKETEFLLLQIFGRKSYPMLKLVRMKLWFTRFKNINPFPVPRDLPQDPVDLASLALRHMEPDLSARVTTYQMPLLKDSPNAMDPTETHIVGIQSPEQQSALARHDPARPIFVEGPFSLWLRDKCVYYHILRADLLPPEEREVEEIPEEWNLYYPMQLDLAYGRSSWDDYEFNIDEVEEGPVFAICVAGAHDQATLAKWIQGLQETNPALARIPVVFRLSGSSGELLPSSSELEEPPPPPPEGQEEEEDSQQRQQQGQS", "length": 433 }, "evidence": [ { "id": "A0A5G2R1W8", "url": "https://omabrowser.org/oma/group/A0A5G2R1W8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5XIC2-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "Ecsit", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWVQVNLLARGLSRGWGSICRTVLSGTPFAQPSLQARGLHCSAVTHKDDVWLVPRPSEPQKKPIKVPAMHEDLFRPSGNGEQDKASFLNAVRSFGEHNVRKRGHVDFIYLALRKMPEFGVERDLSVYNLLLDVFPKEVFRPRNAIQRIFVHYPRQQECGVAVLEQMERHGVMPNTETEFLLIQVFGHKSYPMLKFLRMKLWFTRFKNINPYPVPRDLPQDPLDLAKLGLRHMEPDLSAKVTVYQMSLPSESTGIEDPTQPHIVGIQSPDQQAALARHNPSRPVFVEGPFPLWLRNKCVYYHILRADLPPPEEETVEEIPEEWNLYYPMQLDLEYSRSAWDNYEFDMDEVTEGPVFAMCMTGAHDQATLVKWIQGLQETNPTLAQIPVVFRLARSTGELLATTRLEGQSPPHSPPKGPEEDDEAIQAQQRQGQS", "length": 434 }, "evidence": [ { "id": "A0A5G2R1W8", "url": "https://omabrowser.org/oma/group/A0A5G2R1W8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BQ95-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPEPRQRPTKALVPFEDLFGQAPGGERDKASFLQTVQKFAEHSVRKRGHIDFIYLALRKMREYGVERDLAVYNQLLNIFPKEVFRPRNIIQRIFVHYPRQQECGIAVLEQMENHGVMPNKETEFLLIQIFGRKSYPMLKLVRLKLWFPRFMNVNPFPVPRDLPQDPVELAMFGLRHMEPDLSARVTIYQVPLPKDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVFVEGPFSLWLRNKCVYYHILRADLLPPEEREVEETPEEWNLYYPMQLDLEYVRSGWDNYEFDINEVEEGPVFAMCMAGAHDQATMAKWIQGLQETNPTLAQIPVVFRLAGSTRELQTSSAGLEEPPLPEDHQEEDDNLQRQQQGQS", "length": 431 }, "evidence": [ { "id": "A0A5G2R1W8", "url": "https://omabrowser.org/oma/group/A0A5G2R1W8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZH6-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "Ecsit", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSWVQVNLLVRSLSRGWGGLCRPALSGTPFAQVSLQALRGLHCSAATHKDEPWLVPRPPEPQRKPIKVPAMHEDLFKPSGNRERDKASFLNAVRSFGAHNVRKRGHVDFIYLALRKMPEFGVERDLSVYNLLLDVFPKEVFRPRNVIQRIFVHYPRQQECGVAVLEQMERHGVMPSAETEFLLIQIFGRKSYPMLKFLRMKLWFTRFKNINPYPVPRDLPQDPLDLAKLGLRHMEPDLSAKVTVYQMSLPSDSTGMEDPTQPHIVGIQSPDQQAALARHNPSRPVFVEGPFPLWLRNKCVYYHILRADLPPPEEEKVEEIPEEWELYYPQKLDLEYSRSGWDDYEFDVDEVTEGPVFAMCMAGAHDQATLIKWIQGLQETNPTLAQIPVVFRLARSTGELLTTSRLEGQSPPHSPPKGPEEDDETIQAEQQQGQS", "length": 435 }, "evidence": [ { "id": "A0A5G2R1W8", "url": "https://omabrowser.org/oma/group/A0A5G2R1W8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9U6M0-1", "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ECSIT", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRRAQCLLRLHGNGGHSLVSRFRNYATDEGNPKQNPNPNPRAQKPGTKNLPALRNPFAAAQDRTKNSYLTMVEIFQERDVHRRNHVEFIYAALKNMADFGVERDLEVYKALINVMPKGKFIPTNMFQAEFMHYPKQQQCIIDLLEQMEDCGVMPDHEMEAMLLNVFGRQGHPLRKYWRMMYWMPKFKNLSPWPLPDPVPDDTLEMAKLALERMCTVDLRSKITVFETSELKDAIDDTWIVSGMSPEQEKLLREHSRQKALYIEGPFHIWLRNRRINYFTLRADADSEFLSELDERQLDEDDVSHIEVPFFGRAPPRRHNQLGKLRSVHQQDDGTIMAICATGTSTKDSLLSWIRLLEANGNPSIGEVPVLFRFTSEVPAKAEEIEGGASVPATSDNSSQDEHISSRQK", "length": 409 }, "evidence": [ { "id": "A0A5G2R1W8", "url": "https://omabrowser.org/oma/group/A0A5G2R1W8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "pmid": "" }, { "name": "mitochondrial complex I intermediate assembly complex", "id": "GO:0160295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160295", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "pmid": "" }, { "name": "cell surface receptor protein serine/threonine kinase signaling pathway", "id": "GO:0007178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007178", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "pmid": "" }, { "name": "toll-like receptor 4 signaling pathway", "id": "GO:0034142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034142", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "pmid": "" }, { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1W8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1W8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 433, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1W8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1W8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1W8" }, { "id": "SM01284", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01284" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ECSIT C-terminal", "eco_id": "ECO_0000259", "start_pos": 269, "end_pos": 394, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 260 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R614-1", "uniprot_ac": "A0A5G2R614", "uniprot_id": "A0A5G2R614_PIG", "mass": { "chemical_mass": 57307.0, "monoisotopic_mass": 57307.0 }, "refseq": { "ac": "XP_020932350", "name": "cell division cycle protein 20 homolog B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932350" }, "gene_names": [ { "name": "CDC20B", "type": "recommended", "evidence": [ { "id": "A0A5G2R614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614" } ] }, { "name": "CDC20B", "type": "synonym", "evidence": [ { "id": "XP_020932350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932350" } ] } ], "protein_names": [ { "name": "Cell division cycle 20B", "type": "synonym", "evidence": [ { "id": "A0A5G2R614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614/entry#names_and_taxonomy" } ] }, { "name": "cell division cycle protein 20 homolog B", "type": "synonym", "evidence": [ { "id": "XP_020932350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932350" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R614", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CDC20B", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614", "locus": { "chromosome": "16", "start_pos": 34294272, "end_pos": 34349242, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000048484", "url": "https://www.ensembl.org/id/ENSSSCG00000048484" } ] } } ], "crossref": [ { "id": "A0A5G2R614", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R614", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000048484", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000048484", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100620954", "url": "https://www.ncbi.nlm.nih.gov/gene/100620954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100620954", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620954", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R614", "url": "https://www.orthodb.org/?gene=A0A5G2R614", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19918", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19918", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19918:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19918:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24807", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24807", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020932350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932350", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QMV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R614", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R614-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEWKLERTARRRIRTEEEMLWEDVMRVLAKDMKQKRGQGSPKVFDVVNTTYSNFKSNFAKRLSAEVPVASSPITTRWRQSQTRDVAAHSFGEEHSTTDLAETVLRMTPEKETLSPGSYKEPLKNPNKGSFETSNSAFHFCKASHALDRGWKENVASTGQKCLNQLFSTQKVAQQVNGKMQLCEQPQCIWKGCNDGVKDGYFYIQSFSDTNYSILQPEVKIHLTGLRNDYYLNILDWNFQNLVAIALGSSVHIWNGESHSGIENIDLSLTCNYVSSVSWIEKGNCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHCILSSGSRLGRVYHHDVRVAQHRVGTLHHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGVTAQGHALKVIPQPTAVKAVDWCPWKSEVLAVGGGMKDGHLHILDINTGQSIQTPSTNSQICSLVWLPKTKEIATGQGSPKNDVTVWACPALARSRGFFGHRGRVLHLALSPDQTKVFSAAADGIACVWNCC", "length": 516, "header": "tr|A0A5G2R614-1|A0A5G2R614_PIG Isoform 1 of Cell division cycle 20B OS=Sus scrofa OX=9823 GN=CDC20B PE=3 SV=1 CANONICAL=A0A5G2R614-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QMV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614/entry#A0A5G2QMV6-1", "sequence": { "sequence": "MEWKLERTARRRIRTEEEMLWEDVMRVLAKDMKQKRGQGSPKVFDVVNTTYSNFKSNFAKRLSAEVPVASSPITTRWRQSQTRDVAAHSFGEEHSTTDLAETVLRMTPEKETLSPGSYKEPLKNPNKGSFETSNSAFHFCKASHALDRGWKENVASTGQKCLNQLFSTQKVAQQVNGKMQLCEQPQCIWKGCNDGVKDGYFYIQSFSDTNYSILQPEVKIHLTGLRNDYYLNILDWNFQNLVAIALGSSVHIWNGESHSGIENIDLSLTCNYVSSVSWIEKGNCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHCILSSGSRLGRVYHHDVRVAQHRVGTLHHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGVTAQGHALKVIPQPTAVKICSLVWLPKTKEIATGQGSPKNDVTVWACPALARSRGFFGHRGRVLHLALSPDQTKVFSAAADGIACVWNCC", "length": 474, "header": "tr|A0A5G2QMV6-1|A0A5G2R614_PIG Computationally mapped isoform of Cell division cycle 20B OS=Sus scrofa OX=9823 GN=CDC20B PE=3 SV=1 CANONICAL=A0A5G2R614-1" }, "locus": { "chromosome": "16", "start_pos": 34349043, "end_pos": 34295276, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073072.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073072.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059646.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059646.1" } ] } }, { "isoform_ac": "A0A5G2R614-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614/entry#A0A5G2R614-1", "sequence": { "sequence": "MEWKLERTARRRIRTEEEMLWEDVMRVLAKDMKQKRGQGSPKVFDVVNTTYSNFKSNFAKRLSAEVPVASSPITTRWRQSQTRDVAAHSFGEEHSTTDLAETVLRMTPEKETLSPGSYKEPLKNPNKGSFETSNSAFHFCKASHALDRGWKENVASTGQKCLNQLFSTQKVAQQVNGKMQLCEQPQCIWKGCNDGVKDGYFYIQSFSDTNYSILQPEVKIHLTGLRNDYYLNILDWNFQNLVAIALGSSVHIWNGESHSGIENIDLSLTCNYVSSVSWIEKGNCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHCILSSGSRLGRVYHHDVRVAQHRVGTLHHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGVTAQGHALKVIPQPTAVKAVDWCPWKSEVLAVGGGMKDGHLHILDINTGQSIQTPSTNSQICSLVWLPKTKEIATGQGSPKNDVTVWACPALARSRGFFGHRGRVLHLALSPDQTKVFSAAADGIACVWNCC", "length": 516, "header": "tr|A0A5G2R614-1|A0A5G2R614_PIG Isoform 1 of Cell division cycle 20B OS=Sus scrofa OX=9823 GN=CDC20B PE=3 SV=1 CANONICAL=A0A5G2R614-1" }, "locus": { "chromosome": "16", "start_pos": 34349043, "end_pos": 34295276, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089207.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089207.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072529.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072529.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QMV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMV6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100620954", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620954", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ubiquitin-protein transferase activator activity", "id": "GO:0097027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097027", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R614", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614" } ], "pmid": "" }, { "name": "anaphase-promoting complex binding", "id": "GO:0010997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010997", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R614", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614" } ], "pmid": "" }, { "name": "ubiquitin ligase activator activity", "id": "GO:1990757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990757", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R614", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R614", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614" } ], "pmid": "" }, { "name": "deuterosome", "id": "GO:0098536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098536", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R614", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R614", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614" } ], "pmid": "" }, { "name": "positive regulation of anaphase-promoting complex-dependent catabolic process", "id": "GO:1905786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905786", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R614", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614" } ], "pmid": "" }, { "name": "de novo centriole assembly", "id": "GO:0097742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097742", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R614", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R614-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 516, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R614-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R614" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R614" }, { "id": "PF24807", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24807" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CDC20/Fizzy WD40", "eco_id": "ECO_0000259", "start_pos": 224, "end_pos": 513, "start_aa": "Gly", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 48, "end_pos": 50 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZN1-1", "uniprot_ac": "A0A5G2QZN1", "uniprot_id": "A0A5G2QZN1_PIG", "mass": { "chemical_mass": 25727.0, "monoisotopic_mass": 25727.0 }, "refseq": {}, "gene_names": [ { "name": "QDPR", "type": "recommended", "evidence": [ { "id": "A0A5G2QZN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1" } ] } ], "protein_names": [ { "name": "Dihydropteridine reductase", "type": "recommended", "evidence": [ { "id": "A0A5G2QZN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1/entry#names_and_taxonomy" } ] }, { "name": "1.5.1.34", "type": "synonym", "evidence": [ { "id": "A0A5G2QZN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1/entry#names_and_taxonomy" } ] }, { "name": "HDHPR", "type": "synonym", "evidence": [ { "id": "A0A5G2QZN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1/entry#names_and_taxonomy" } ] }, { "name": "Quinoid dihydropteridine reductase", "type": "synonym", "evidence": [ { "id": "A0A5G2QZN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the conversion of quinonoid dihydrobiopterin into tetrahydrobiopterin.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1#function" }, { "database": "UniProtKB", "id": "ARBA00037099", "url": "https://www.uniprot.org/uniprotkb/ARBA00037099#function" }, { "database": "UniProtKB", "id": "A0A5G2QR20", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR20#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "QDPR", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1", "locus": { "chromosome": "8", "start_pos": 12529512, "end_pos": 12549603, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034811", "url": "https://www.ensembl.org/id/ENSSSCG00000034811" } ] } } ], "crossref": [ { "id": "A0A5G2QZN1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034811", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034811", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05334", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05334", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15104", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15104", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15104:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15104:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8964208", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964208", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17865", "url": "https://www.rhea-db.org/rhea/17865", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "17869", "url": "https://www.rhea-db.org/rhea/17869", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QR20", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QR20-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAAGEARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASANVVVKMTDSFTEQADQVTAEVGKLLGAEKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSMWTSTISSHLATKHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKDSGMPSGAAAIAVLPVTLDTPLNRKSMPHADFSSWTPLEFLVETFHDWIIEKNRPSSGSLIQVVTTQGKTELTPAYF", "length": 243, "header": "tr|A0A5G2QZN1-1|A0A5G2QZN1_PIG Isoform 1 of Dihydropteridine reductase OS=Sus scrofa OX=9823 GN=QDPR PE=3 SV=2 CANONICAL=A0A5G2QZN1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QR20-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1/entry#A0A5G2QR20-1", "sequence": { "sequence": "MAAAAAGEARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASANVVVKMTDSFTEQADQVTAEVGKLLGAEKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSMWTSTISSHLATKHLKEGGLLTLAGAKAALDGTPGSPWTRP", "length": 151, "header": "tr|A0A5G2QR20-1|A0A5G2QZN1_PIG Computationally mapped isoform of Dihydropteridine reductase OS=Sus scrofa OX=9823 GN=QDPR PE=3 SV=1 CANONICAL=A0A5G2QZN1-1" }, "locus": { "chromosome": "8", "start_pos": 12549455, "end_pos": 12531867, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080758.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080758.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067189.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067189.1" } ] } }, { "isoform_ac": "A0A5G2QZN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1/entry#A0A5G2QZN1-1", "sequence": { "sequence": "MAAAAAGEARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASANVVVKMTDSFTEQADQVTAEVGKLLGAEKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSMWTSTISSHLATKHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKDSGMPSGAAAIAVLPVTLDTPLNRKSMPHADFSSWTPLEFLVETFHDWIIEKNRPSSGSLIQVVTTQGKTELTPAYF", "length": 243, "header": "tr|A0A5G2QZN1-1|A0A5G2QZN1_PIG Isoform 1 of Dihydropteridine reductase OS=Sus scrofa OX=9823 GN=QDPR PE=3 SV=2 CANONICAL=A0A5G2QZN1-1" }, "locus": { "chromosome": "8", "start_pos": 12549455, "end_pos": 12530122, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070258.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070258.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070341.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070341.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QR20", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR20" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8964208", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964208", "resource": "Reactome", "description": "Phenylalanine metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tetrahydrobiopterin biosynthetic process", "id": "GO:0006729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006729", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1" } ], "pmid": "" }, { "name": "L-phenylalanine catabolic process", "id": "GO:0006559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006559", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "6,7-dihydropteridine reductase activity", "id": "GO:0004155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1" } ], "pmid": "" }, { "name": "NADPH binding", "id": "GO:0070402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070402", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1" } ], "pmid": "" }, { "name": "NADH binding", "id": "GO:0070404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070404", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17865", "name": "", "equation": "5,6,7,8-tetrahydropteridine + NADP(+) = 6,7-dihydropteridine + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17865", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17865" } ] }, { "id": "17869", "name": "", "equation": "5,6,7,8-tetrahydropteridine + NAD(+) = 6,7-dihydropteridine + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17869", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17869" } ] }, { "id": "R-SSC-71130", "name": "q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-71129" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-71130", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71130" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-71129", "participant_name": "qDHB [cytosol]", "crossref": [ { "id": "43120", "database": "ChEBI", "url": "" }, { "id": "HMDB0002215", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZN1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 243, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZN1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZN1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QX49-1", "uniprot_ac": "A0A5G2QX49", "uniprot_id": "A0A5G2QX49_PIG", "mass": { "chemical_mass": 62051.0, "monoisotopic_mass": 62051.0 }, "refseq": { "ac": "XP_005674038", "name": "SRSF protein kinase 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005674038" }, "gene_names": [ { "name": "SRPK3", "type": "recommended", "evidence": [ { "id": "A0A5G2QX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49" } ] }, { "name": "MSSK-1", "type": "synonym", "evidence": [ { "id": "XP_005674038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005674038" } ] }, { "name": "MSSK1", "type": "synonym", "evidence": [ { "id": "XP_005674038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005674038" } ] }, { "name": "SRPK3", "type": "synonym", "evidence": [ { "id": "XP_005674038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005674038" } ] }, { "name": "STK23", "type": "synonym", "evidence": [ { "id": "XP_005674038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005674038" } ] } ], "protein_names": [ { "name": "SRSF protein kinase 3", "type": "recommended", "evidence": [ { "id": "A0A5G2QX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A5G2QX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49/entry#names_and_taxonomy" } ] }, { "name": "Muscle-specific serine kinase 1", "type": "synonym", "evidence": [ { "id": "A0A5G2QX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49/entry#names_and_taxonomy" } ] }, { "name": "SRSF protein kinase 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005674038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005674038" } ] }, { "name": "Serine/arginine-rich protein-specific kinase 3", "type": "synonym", "evidence": [ { "id": "A0A5G2QX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49/entry#names_and_taxonomy" } ] }, { "name": "Serine/threonine-protein kinase 23", "type": "synonym", "evidence": [ { "id": "A0A5G2QX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49#function" }, { "database": "UniProtKB", "id": "ARBA00058217", "url": "https://www.uniprot.org/uniprotkb/ARBA00058217#function" }, { "database": "UniProtKB", "id": "I3LC38", "url": "https://www.uniprot.org/uniprotkb/I3LC38#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SRPK3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49", "locus": {} } ], "crossref": [ { "id": "A0A5G2QX49", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX49", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000024676", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000024676", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14218", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14218", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100240720", "url": "https://www.ncbi.nlm.nih.gov/gene/100240720", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QX49", "url": "https://www.orthodb.org/?gene=A0A5G2QX49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47634", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47634", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47634:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47634:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005674038", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005674038", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QRM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX49-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RB70", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RB70-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LC38", "url": "https://www.uniprot.org/uniprotkb/I3LC38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LC38-1", "url": "https://www.uniprot.org/uniprotkb/I3LC38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSASTGGGGGGDSGGSSSSSSQASCGPESSGSELAPPTPAPRMLQGLLGSDDEEQEDPKDYCKGGYYPVKIGDLFNGRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPKRETIVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQSGAPPPSRSTVSTAPQEVLQSGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAAAQAEDSGSRLEGGSGSTSSSGCHPGGAGPGPSPASSSPAPGGDRSLSPGSQTSGFSGSLFSPASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIRIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP", "length": 567, "header": "tr|A0A5G2QX49-1|A0A5G2QX49_PIG Isoform 1 of SRSF protein kinase 3 OS=Sus scrofa OX=9823 GN=SRPK3 PE=4 SV=2 CANONICAL=A0A5G2QX49-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49/entry#A0A5G2QRM9-1", "sequence": { "sequence": "MSASTGGGGGGDSGGSSSSSSQASCGPESSGSELAPPTPAPRMLQGLLGSDDEEQEDPKDYCKGGYYPVKIGDLFNGRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPKRETIVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQSGAPPPSRSTVSTAPQEVLLSGPALSTRPKLPWAAAGLATAPAEGRMPSKAGRAQGQPCWFLPNLELWQQSGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAAAQAEDSGSRLEGGSGSTSSSGCHPGGAGPGPSPASSSPAPGGDRSLSPGSQTSGFSGSLFSPASCSILSGSSNQRETGGLLSPSKPQNADKIRIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP", "length": 604, "header": "tr|A0A5G2QRM9-1|A0A5G2QX49_PIG Computationally mapped isoform of SRSF protein kinase 3 OS=Sus scrofa OX=9823 GN=SRPK3 PE=4 SV=1 CANONICAL=A0A5G2QX49-1" }, "locus": { "chromosome": "X", "start_pos": 124528334, "end_pos": 124524173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091343.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091343.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067424.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067424.1" } ] } }, { "isoform_ac": "A0A5G2QX49-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49/entry#A0A5G2QX49-1", "sequence": { "sequence": "MSASTGGGGGGDSGGSSSSSSQASCGPESSGSELAPPTPAPRMLQGLLGSDDEEQEDPKDYCKGGYYPVKIGDLFNGRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPKRETIVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQSGAPPPSRSTVSTAPQEVLQSGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAAAQAEDSGSRLEGGSGSTSSSGCHPGGAGPGPSPASSSPAPGGDRSLSPGSQTSGFSGSLFSPASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIRIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP", "length": 567, "header": "tr|A0A5G2QX49-1|A0A5G2QX49_PIG Isoform 1 of SRSF protein kinase 3 OS=Sus scrofa OX=9823 GN=SRPK3 PE=4 SV=2 CANONICAL=A0A5G2QX49-1" }, "locus": { "chromosome": "X", "start_pos": 124528334, "end_pos": 124524173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072582.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072582.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068725.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068725.2" } ] } }, { "isoform_ac": "A0A5G2RB70-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49/entry#A0A5G2RB70-1", "sequence": { "sequence": "MSASTGGGGGGDSGGSSSSSSQASCGPESSGSELAPPTPAPRMLQGLLGSDDEEQEDPKDYCKGGYYPVKIGDLFNGRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPKRETIVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQSGAPPPSRSTVSTAPQEVLSGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAAAQAEAPFGASNLLVNPLEPQNADKIRIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP", "length": 486, "header": "tr|A0A5G2RB70-1|A0A5G2RB70_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SRPK3 PE=3 SV=2 CANONICAL=A0A5G2QX49-1" }, "locus": { "chromosome": "X", "start_pos": 124528334, "end_pos": 124524173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081126.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081126.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071400.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071400.2" } ] } }, { "isoform_ac": "I3LC38-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49/entry#I3LC38-1", "sequence": { "sequence": "MSASTGGGGGGDSGGSSSSSSQASCGPESSGSELAPPTPAPRMLQGLLGSDDEEQEDPKDYCKGGYYPVKIGDLFNGRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPKRETIVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQSGAPPPSRSTVSTAPQEVLSGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAAAQAEDSGSRLEGGSGSTSSSGCFSGSLFSPASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIRIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP", "length": 534, "header": "tr|I3LC38-1|A0A5G2QX49_PIG Computationally mapped isoform of SRSF protein kinase 3 OS=Sus scrofa OX=9823 GN=SRPK3 PE=4 SV=3 CANONICAL=A0A5G2QX49-1" }, "locus": { "chromosome": "X", "start_pos": 124528334, "end_pos": 124524173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029367.4", "url": "https://www.ensembl.org/id/ENSSSCT00000029367.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021611.3", "url": "https://www.ensembl.org/id/ENSSSCP00000021611.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 38, "start_aa": "Thr", "end_pos": 38, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr38", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LC38", "url": "https://www.uniprot.org/uniprotkb/I3LC38" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49" } ], "pmid": "" }, { "name": "regulation of mRNA processing", "id": "GO:0050684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050684", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QX49-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 567, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QX49-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX49" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX49" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 565, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 38 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R222-1", "uniprot_ac": "A0A5G2R222", "uniprot_id": "A0A5G2R222_PIG", "mass": { "chemical_mass": 109903.0, "monoisotopic_mass": 109903.0 }, "refseq": {}, "gene_names": [ { "name": "INPP4A", "type": "recommended", "evidence": [ { "id": "A0A5G2R222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" } ] } ], "protein_names": [ { "name": "Inositol polyphosphate-4-phosphatase type I A", "type": "recommended", "evidence": [ { "id": "A0A5G2R222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.66", "type": "synonym", "evidence": [ { "id": "A0A5G2R222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222/entry#names_and_taxonomy" } ] }, { "name": "Inositol polyphosphate 4-phosphatase type I", "type": "synonym", "evidence": [ { "id": "A0A5G2R222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222/entry#names_and_taxonomy" } ] }, { "name": "Type I inositol 3,4-bisphosphate 4-phosphatase", "type": "synonym", "evidence": [ { "id": "A0A5G2R222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R222", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "INPP4A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222", "locus": { "chromosome": "3", "start_pos": 55711031, "end_pos": 55834367, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008190", "url": "https://www.ensembl.org/id/ENSSSCG00000008190" } ] } } ], "crossref": [ { "id": "A0A5G2R222", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R222", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008190", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008190", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04048", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04048", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12187", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12187", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12187:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12187:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1660516", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660516", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1855183", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855183", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "43388", "url": "https://www.rhea-db.org/rhea/43388", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43392", "url": "https://www.rhea-db.org/rhea/43392", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QS20", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS20-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R222", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R222-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3C2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3C2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBL8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STD8", "url": "https://www.uniprot.org/uniprotkb/F1STD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STD8-1", "url": "https://www.uniprot.org/uniprotkb/F1STD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNDPIFLSSIAFFQDSLINQMTQIKLSVYDVKDRSQGTMYLLGSGTFIVKDLLQDRRHRLYLTLRSAESDRVGNITVMGWQMEEKSDQRPPVTRSLDTVNGRMVLPDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTEGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTVILTYQENLTDLHQYKGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSSCQSIIYIPQDIVRAKEIIAQINTLKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLATSIHGLNAARPDYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQRERLQSGGCEDGFPCAGSCTGKKGNRGSRAYWIRPEDPFCDLPSSPCPSTTPSTACRPHPTTHCSPPPEEASPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATFLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSNASTDMLPVITGNRDGFNVRIPLPGPLFDALPRELQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHYRPPEGTYGKVET", "length": 976, "header": "tr|A0A5G2R222-1|A0A5G2R222_PIG Isoform 1 of Inositol polyphosphate-4-phosphatase type I A OS=Sus scrofa OX=9823 GN=INPP4A PE=1 SV=2 CANONICAL=A0A5G2R222-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QS20-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222/entry#A0A5G2QS20-1", "sequence": { "sequence": "MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNDPIFLSSIAFFQDSLINQMTQIKLSVYDVKDRSQGTMYLLGSGTFIVKDLLQDRRHRLYLTLRSAESDRVGNITVMGWQMEEKSDQRPPVTRSLDTVNGRVSSLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTEGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTVILTYQENLTDLHQYKGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLHKFEETKKHTSSSCQSIIYIPQDIVRAKEIIAQINTLKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLATSIHGLNAARPDYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQRERLQSGGCEDGFPCAGSCTGKKGNRGSRAYWIRPEDPFCDLPSSPCPSTTPSTACRPHPTTRAYASTLPPPRRVSEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATFLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSNASTDMLPVITGNRDGFNVRIPLPGPLFDALPRELQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHYRPPEGTYGKVET", "length": 969, "header": "tr|A0A5G2QS20-1|A0A5G2R222_PIG Computationally mapped isoform of Inositol polyphosphate-4-phosphatase type I A OS=Sus scrofa OX=9823 GN=INPP4A PE=1 SV=2 CANONICAL=A0A5G2R222-1" }, "locus": { "chromosome": "3", "start_pos": 55760365, "end_pos": 55713535, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087935.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087935.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067720.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067720.2" } ] } }, { "isoform_ac": "A0A5G2R222-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222/entry#A0A5G2R222-1", "sequence": { "sequence": "MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNDPIFLSSIAFFQDSLINQMTQIKLSVYDVKDRSQGTMYLLGSGTFIVKDLLQDRRHRLYLTLRSAESDRVGNITVMGWQMEEKSDQRPPVTRSLDTVNGRMVLPDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTEGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTVILTYQENLTDLHQYKGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSSCQSIIYIPQDIVRAKEIIAQINTLKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLATSIHGLNAARPDYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQRERLQSGGCEDGFPCAGSCTGKKGNRGSRAYWIRPEDPFCDLPSSPCPSTTPSTACRPHPTTHCSPPPEEASPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATFLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSNASTDMLPVITGNRDGFNVRIPLPGPLFDALPRELQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHYRPPEGTYGKVET", "length": 976, "header": "tr|A0A5G2R222-1|A0A5G2R222_PIG Isoform 1 of Inositol polyphosphate-4-phosphatase type I A OS=Sus scrofa OX=9823 GN=INPP4A PE=1 SV=2 CANONICAL=A0A5G2R222-1" }, "locus": { "chromosome": "3", "start_pos": 55760365, "end_pos": 55713535, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085463.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085463.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064578.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064578.2" } ] } }, { "isoform_ac": "A0A5G2R3C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222/entry#A0A5G2R3C2-1", "sequence": { "sequence": "MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNDPIFLSSIAFFQDSLINQMTQIKLSVYDVKDRSQGTMYLLGSGTFIVKDLLQDRRHRLYLTLRSAESDRVGNITVMGWQMEEKSDQRPPVTRSLDTVNGRMVLPDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTEGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTVILTYQENLTDLHQYKGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSSCQSIIYIPQDIVRAKEIIAQINTLKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLATSIHGLNAARPDYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQRERLQSGGCEDGFPCAGSCTGKKDCSPPPEEASPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATFLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSNASTDMLPVITGNRDGFNVRIPLPGPLFDALPRELQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNLSGLVPIRDLRLDPSLLCSIPLLALSPNLLIVWLFLSIAYLVAKLRCK", "length": 953, "header": "tr|A0A5G2R3C2-1|A0A5G2R3C2_PIG Computationally mapped isoform of Inositol polyphosphate-4-phosphatase type I A OS=Sus scrofa OX=9823 GN=INPP4A PE=1 SV=1 CANONICAL=A0A5G2R222-1" }, "locus": { "chromosome": "3", "start_pos": 55760365, "end_pos": 55718197, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070168.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070168.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071693.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071693.1" } ] } }, { "isoform_ac": "A0A8W4FBL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222/entry#A0A8W4FBL8-1", "sequence": { "sequence": "MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNDPIFLSSIAFFQDSLINQMTQIKLSVYDVKDRSQGTMYLLGSGTFIVKDLLQDRRHRLYLTLRSAESDRVGNITVMGWQMEEKSDQRPPVTRSLDTVNGRVSSLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTEGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTVILTYQENLTDLHQYKGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLHKFEETKKHTSSSCQSIIYIPQDIVRAKEIIAQINTLKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLATSIHGLNAARPDYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQRERLQSGGCEDGFPCAGSCTGKKDCSPPPEEASPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATFLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTFKVTQATSNASTDMLPVITGNRDGFNVRIPLPGPLFDALPRELQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNLSGLVPIRDLRLDPSLLCSIPLLALSPNLLIVWLFLSIAYLVAKLRCK", "length": 944, "header": "tr|A0A8W4FBL8-1|A0A5G2R222_PIG Computationally mapped isoform of Inositol polyphosphate-4-phosphatase type I A OS=Sus scrofa OX=9823 GN=INPP4A PE=1 SV=1 CANONICAL=A0A5G2R222-1" }, "locus": { "chromosome": "3", "start_pos": 55760365, "end_pos": 55718197, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103289.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103289.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075691.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075691.1" } ] } }, { "isoform_ac": "F1STD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222/entry#F1STD8-1", "sequence": { "sequence": "MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQATSNASTDMLPVITGNRDGFNVRIPLPGPLFDALPRELQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHYRPPEGTYGKVET", "length": 306, "header": "tr|F1STD8-1|A0A5G2R222_PIG Computationally mapped isoform of Inositol polyphosphate-4-phosphatase type I A OS=Sus scrofa OX=9823 GN=INPP4A PE=1 SV=5 CANONICAL=A0A5G2R222-1" }, "locus": { "chromosome": "3", "start_pos": 55760365, "end_pos": 55713535, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008969.5", "url": "https://www.ensembl.org/id/ENSSSCT00000008969.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008743.5", "url": "https://www.ensembl.org/id/ENSSSCP00000008743.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QS20", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS20" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" }, { "id": "R-SSC-1660516", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660516", "resource": "Reactome", "description": "Synthesis of PIPs at the early endosome membrane" }, { "id": "R-SSC-1855183", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855183", "resource": "Reactome", "description": "Synthesis of IP2, IP, and Ins in the cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R222", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R222", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R222", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R222", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R222", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R222", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R222", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R222", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small molecule metabolic process", "id": "GO:0044281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044281", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R222", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity", "id": "GO:0016316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016316", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R222", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 740, "end_pos": 742, "annotation": "n_glycosylation_sequon" }, { "start_pos": 751, "end_pos": 753, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "43388", "name": "", "equation": "1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "43388", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43388" } ] }, { "id": "43392", "name": "", "equation": "1D-myo-inositol 1,3,4-trisphosphate + H2O = 1D-myo-inositol 1,3-bisphosphate + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "43392", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43392" } ] }, { "id": "R-SSC-1676162", "name": "PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, early endosome membrane", "input_participant_list": [ "R-ALL-1806238" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1676162", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1676162" } ] }, { "id": "R-SSC-1676164", "name": "PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1676164", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1676164" } ] }, { "id": "R-SSC-1855180", "name": "I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-1629769" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1855180", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855180" } ] }, { "id": "R-SSC-1855202", "name": "I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1629746" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1855202", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855202" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1629746", "participant_name": "I(3,4)P2 [cytosol]", "crossref": [ { "id": "83241", "database": "ChEBI", "url": "" }, { "id": "ZINC000004096300", "database": "ZINC", "url": "" }, { "id": "C04063", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-1629769", "participant_name": "I(1,3)P2 [cytosol]", "crossref": [ { "id": "83242", "database": "ChEBI", "url": "" }, { "id": "C04062", "database": "COMPOUND", "url": "" }, { "id": "ZINC000100016181", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-1806238", "participant_name": "PI(3,4)P2 [early endosome membrane]", "crossref": [ { "id": "16152", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R222-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 976, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R222-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R222" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R222" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 153, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 740, "end_pos": 742 }, { "start_pos": 751, "end_pos": 753 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1I1-1", "uniprot_ac": "A0A5G2R1I1", "uniprot_id": "A0A5G2R1I1_PIG", "mass": { "chemical_mass": 38725.0, "monoisotopic_mass": 38725.0 }, "refseq": {}, "gene_names": [ { "name": "SIRT3", "type": "recommended", "evidence": [ { "id": "A0A5G2R1I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ] } ], "protein_names": [ { "name": "Sirtuin 3", "type": "synonym", "evidence": [ { "id": "A0A5G2R1I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "NAD-dependent protein deacetylase.", "evidence": [ { "database": "UniProtKB", "id": "F6PS90", "url": "https://www.uniprot.org/uniprotkb/F6PS90#function" }, { "database": "UniProtKB", "id": "PIRNR037938", "url": "https://www.uniprot.org/uniprotkb/PIRNR037938#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SIRT3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1", "locus": { "chromosome": "2", "start_pos": 38464, "end_pos": 55101, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014558", "url": "https://www.ensembl.org/id/ENSSSCG00000014558" } ] } } ], "crossref": [ { "id": "A0A5G2R1I1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1I1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014558", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014558", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01408", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01408", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11085", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11085", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11085:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11085:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02146", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02146", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2151201", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2151201", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9617629", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9617629", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9841251", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9841251", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9854311", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9854311", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "43636", "url": "https://www.rhea-db.org/rhea/43636", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83535", "url": "https://www.rhea-db.org/rhea/83535", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QT49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QT49-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0N0T2", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N0T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0N0T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N0T2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PS90", "url": "https://www.uniprot.org/uniprotkb/F6PS90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PS90-1", "url": "https://www.uniprot.org/uniprotkb/F6PS90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALWCRSSVAALRLWSLGGFCSWTRRPRITGGRRSISFSPGASGVCGSGGNSKKQLLLQDIAELIKTRACRRVVVMVGAGISTPSGIPDFRSPGTGYYSTLQSYDLPYPEAIFELSFFFHNPKPFFTFAKELYPGNYRPNTAHYFLRLLHDKGLLLRLYTQNIDGLERASGIPASKLVEAHGSFASATCTVCRRPFPGEDFWADVMVDSVPRCRVCAGVVKPDIVFFGEPLPPRFLLHLADFPVADLLLILGTSLEVEPFASLSEAVRSSVPRLLINRDLVGTLARHPRGRDVVQLGDLVHGVKRLVELLGWTEEMQDLIQQETGKVRIAEQSQEGRFLCCGVGPPGMEPQ", "length": 351, "header": "tr|A0A5G2R1I1-1|A0A5G2R1I1_PIG Isoform 1 of Sirtuin 3 OS=Sus scrofa OX=9823 GN=SIRT3 PE=1 SV=1 CANONICAL=A0A5G2R1I1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QT49-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1/entry#A0A5G2QT49-1", "sequence": { "sequence": "NQSLPAGGGHGRGRHQHAQRHSRLQVPKHPCAPAWPPSCPWLAPPPCSLLKGSAPFTSLCRSPGTGYYSTLQSYDLPYPEAIFELSFFFHNPKPFFTFAKELYPGNYRPNTAHYFLRLLHDKGLLLRLYTQNIDGLERASGIPASKLVEAHGSFASATCTVCRRPFPGEDFWADVMVDSVPRCRVCAGVVKPDIVFFGEPLPPRFLLHLADFPVADLLLILGTSLEVEPFASLSEAVRSSVPRLLINRDLVGTLARHPRGRDVVQLGDLVHGVKRLVELLGWTEEMQDLIQQETGKVRIAESHGW", "length": 305, "header": "tr|A0A5G2QT49-1|A0A5G2R1I1_PIG Computationally mapped isoform of Sirtuin 3 OS=Sus scrofa OX=9823 GN=SIRT3 PE=1 SV=2 CANONICAL=A0A5G2R1I1-1" }, "locus": { "chromosome": "2", "start_pos": 49322, "end_pos": 40443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090597.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090597.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067321.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067321.2" } ] } }, { "isoform_ac": "A0A5G2R1I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1/entry#A0A5G2R1I1-1", "sequence": { "sequence": "MALWCRSSVAALRLWSLGGFCSWTRRPRITGGRRSISFSPGASGVCGSGGNSKKQLLLQDIAELIKTRACRRVVVMVGAGISTPSGIPDFRSPGTGYYSTLQSYDLPYPEAIFELSFFFHNPKPFFTFAKELYPGNYRPNTAHYFLRLLHDKGLLLRLYTQNIDGLERASGIPASKLVEAHGSFASATCTVCRRPFPGEDFWADVMVDSVPRCRVCAGVVKPDIVFFGEPLPPRFLLHLADFPVADLLLILGTSLEVEPFASLSEAVRSSVPRLLINRDLVGTLARHPRGRDVVQLGDLVHGVKRLVELLGWTEEMQDLIQQETGKVRIAEQSQEGRFLCCGVGPPGMEPQ", "length": 351, "header": "tr|A0A5G2R1I1-1|A0A5G2R1I1_PIG Isoform 1 of Sirtuin 3 OS=Sus scrofa OX=9823 GN=SIRT3 PE=1 SV=1 CANONICAL=A0A5G2R1I1-1" }, "locus": { "chromosome": "2", "start_pos": 54515, "end_pos": 40462, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081934.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081934.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070969.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070969.1" } ] } }, { "isoform_ac": "A0A8D0N0T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1/entry#A0A8D0N0T2-1", "sequence": { "sequence": "NQSLPAGGGHGRGRHQHAQRHSRLQVPKHPCAPAWPPSCPWLAPPPCSLLKGSAPFTSLCRSPGTGYYSTLQSYDLPYPEAIFELSFFFHNPKPFFTFAKELYPGNYRPNTAHYFLRLLHDKGLLLRLYTQNIDGLERASGIPASKLVEAHGSFASATCTVCRRPFPGEDFWADVMVDSVPRCRVCAGVVKPDIVFFGEPLPPRFLLHLADFPVADLLLILGTSLEVEPFASLSEAVRSSVPRLLINRDLVGTLARHPRGRDVVQLGDLVHGVKRLVELLGWTEEMQDLIQQETGKFDGWDK", "length": 302, "header": "tr|A0A8D0N0T2-1|A0A5G2R1I1_PIG Computationally mapped isoform of Sirtuin 3 OS=Sus scrofa OX=9823 GN=SIRT3 PE=1 SV=1 CANONICAL=A0A5G2R1I1-1" }, "locus": { "chromosome": "2", "start_pos": 49322, "end_pos": 38937, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067030.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067030.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068988.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068988.1" } ] } }, { "isoform_ac": "F6PS90-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1/entry#F6PS90-1", "sequence": { "sequence": "MALWCRSSVAALRLWSLGGFCSWTRRPRITGGRRSISFSPGASGVCGSGGNSKKQLLLQDIAELIKTRACRRVVVMVGAGISTPSGIPDFRSPGTGYYSTLQSYDLPYPEAIFELSFFFHNPKPFFTFAKELYPGNYRPNTAHYFLRLLHDKGLLLRLYTQNIDGLERASGIPASKLVEAHGSFASATCTVCRRPFPGEDFWADVMVDSVPRCRVCAGVVKPDIVFFGEPLPPRFLLHLADFPVADLLLILGTSLEVEPFASLSEAVRSSVPRLLINRDLLGDLVHGVKRLVELLGWTEEMQDLIQQETGKFDGWDK", "length": 317, "header": "tr|F6PS90-1|F6PS90_PIG Computationally mapped isoform of NAD-dependent protein deacetylase OS=Sus scrofa OX=9823 GN=SIRT3 PE=1 SV=2 CANONICAL=A0A5G2R1I1-1" }, "locus": { "chromosome": "2", "start_pos": 54515, "end_pos": 38937, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015908.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015908.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015488.4", "url": "https://www.ensembl.org/id/ENSSSCP00000015488.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT49" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2151201", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2151201", "resource": "Reactome", "description": "Transcriptional activation of mitochondrial biogenesis" }, { "id": "R-SSC-9617629", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9617629", "resource": "Reactome", "description": "Regulation of FOXO transcriptional activity by acetylation" }, { "id": "R-SSC-9841251", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9841251", "resource": "Reactome", "description": "Mitochondrial unfolded protein response (UPRmt)" }, { "id": "R-SSC-9854311", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9854311", "resource": "Reactome", "description": "Maturation of TCA enzymes and regulation of TCA cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" }, { "name": "NAD+ binding", "id": "GO:0070403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070403", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" }, { "name": "histone deacetylase activity, NAD-dependent", "id": "GO:0017136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017136", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" }, { "name": "NAD-dependent protein lysine delactylase activity", "id": "GO:0141208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141208", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of oxidative phosphorylation", "id": "GO:1903862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903862", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" }, { "name": "aerobic respiration", "id": "GO:0009060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009060", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" }, { "name": "positive regulation of ceramide biosynthetic process", "id": "GO:2000304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000304", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial transcription", "id": "GO:1903109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903109", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "43636", "name": "", "equation": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "43636", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43636" } ] }, { "id": "83535", "name": "", "equation": "N(6)-benzoyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-benzoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83535", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83535" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1I1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 351, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1I1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1I1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" }, { "id": "PS50305", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50305" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Deacetylase sirtuin-type", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 313, "start_aa": "Asn", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A5G2QT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT49#function" }, { "id": "A0A5G2QT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT49" }, { "id": "PRU00236", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00236" }, { "id": "A0A8D0N0T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N0T2#function" }, { "id": "A0A8D0N0T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N0T2" } ], "binding_site_uniprot": 159, "amino_acid": "Tyr", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 159, "end_pos": 159, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT49#function" }, { "id": "A0A5G2QT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT49" }, { "id": "PRU00236", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00236" }, { "id": "A0A8D0N0T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N0T2#function" }, { "id": "A0A8D0N0T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N0T2" } ], "binding_site_uniprot": 162, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 162, "end_pos": 162, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT49#function" }, { "id": "A0A5G2QT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT49" }, { "id": "PRU00236", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00236" }, { "id": "A0A8D0N0T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N0T2#function" }, { "id": "A0A8D0N0T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N0T2" } ], "binding_site_uniprot": 183, "amino_acid": "Ser", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 183, "end_pos": 183, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT49#function" }, { "id": "A0A5G2QT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT49" }, { "id": "PRU00236", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00236" }, { "id": "A0A8D0N0T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N0T2#function" }, { "id": "A0A8D0N0T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N0T2" } ], "binding_site_uniprot": 186, "amino_acid": "Ser", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 186, "end_pos": 186, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R1I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1#function" }, { "id": "A0A5G2R1I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" }, { "id": "PRU00236", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00236" }, { "id": "F6PS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PS90#function" }, { "id": "F6PS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PS90" }, { "id": "PIRSR037938-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR037938-3" } ], "binding_site_uniprot": 189, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 189, "end_pos": 189, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R1I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1#function" }, { "id": "A0A5G2R1I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" }, { "id": "PRU00236", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00236" }, { "id": "F6PS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PS90#function" }, { "id": "F6PS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PS90" }, { "id": "PIRSR037938-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR037938-3" } ], "binding_site_uniprot": 192, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 192, "end_pos": 192, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R1I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1#function" }, { "id": "A0A5G2R1I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" }, { "id": "PRU00236", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00236" }, { "id": "F6PS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PS90#function" }, { "id": "F6PS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PS90" }, { "id": "PIRSR037938-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR037938-3" } ], "binding_site_uniprot": 213, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 213, "end_pos": 213, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R1I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1#function" }, { "id": "A0A5G2R1I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I1" }, { "id": "PRU00236", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00236" }, { "id": "F6PS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PS90#function" }, { "id": "F6PS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PS90" }, { "id": "PIRSR037938-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR037938-3" } ], "binding_site_uniprot": 216, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 216, "end_pos": 216, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYU9-1", "uniprot_ac": "A0A5G2QYU9", "uniprot_id": "A0A5G2QYU9_PIG", "mass": { "chemical_mass": 222213.0, "monoisotopic_mass": 222213.0 }, "refseq": {}, "gene_names": [ { "name": "MYH3", "type": "recommended", "evidence": [ { "id": "A0A5G2QYU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ] } ], "protein_names": [ { "name": "Myosin heavy chain 3", "type": "synonym", "evidence": [ { "id": "A0A5G2QYU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MYH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9", "locus": { "chromosome": "12", "start_pos": 55347087, "end_pos": 55375353, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000018007", "url": "https://www.ensembl.org/id/ENSSSCG00000018007" } ] } } ], "crossref": [ { "id": "ENSSSCG00000018007", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000018007", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14913", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14913", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45615:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45615:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-390522", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-390522", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QTZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SS61", "url": "https://www.uniprot.org/uniprotkb/F1SS61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SS61-1", "url": "https://www.uniprot.org/uniprotkb/F1SS61-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSTQDGKVTVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPFDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVLKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKEELAKSEAKRKELEEKMVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEEDKVNSLSKIKSKLEQQVDDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFESSQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEATVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDLAGNVESVSKAKANLEKICRTLEDQLSEARGKNEEIQRSMSELTMQKSRLQTEAGELSRQLEEKESTVSQLSRSKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQAEVEDLMVDVDRANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEAALKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKMAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRIKKKMEGDLNEIEIQLSHANRQAAETLKHLRGVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRASLLQAEVEELRASLEQTERARKLAEQELLDANERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKATTDKEQDTSAHLERMKKNLEQTVKDLQHRRGEQLALKGGKKQIQKLEARIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQAKDRKNVLRLQDLVDKLQAKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE", "length": 1928, "header": "tr|A0A5G2QYU9-1|A0A5G2QYU9_PIG Isoform 1 of Myosin heavy chain 3 OS=Sus scrofa OX=9823 GN=MYH3 PE=1 SV=2 CANONICAL=A0A5G2QYU9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QTZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9/entry#A0A5G2QTZ6-1", "sequence": { "sequence": "MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSTQDGKVTVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPFDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVLKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKEELAKSEAKRKELEEKMVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEEDKVNSLSKIKSKLEQQVDDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFESSQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEATVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDLAGNVESVSKAKANLEKICRTLEDQLSEARGKNEEIQRSMSELTMQKSRLQTEAGELSRQLEEKESTVSQLSRSKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQAEVEDLMVDVDRANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEAALKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKMAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRIKKKMEGDLNEIEIQLSHANRQAAETLKHLRGVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRASLLQAEVEELRASLEQTERARKLAEQELLDANERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKATTDKEQDTSAHLERMKKNLEQTVKDLQHLDEEQLALKGGKKQIQKLEARIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE", "length": 1876, "header": "tr|A0A5G2QTZ6-1|A0A5G2QYU9_PIG Computationally mapped isoform of Myosin heavy chain 3 OS=Sus scrofa OX=9823 GN=MYH3 PE=1 SV=2 CANONICAL=A0A5G2QYU9-1" }, "locus": { "chromosome": "12", "start_pos": 55371900, "end_pos": 55351270, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070570.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070570.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065465.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065465.2" } ] } }, { "isoform_ac": "A0A5G2QYU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9/entry#A0A5G2QYU9-1", "sequence": { "sequence": "MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSTQDGKVTVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPFDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVLKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKEELAKSEAKRKELEEKMVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEEDKVNSLSKIKSKLEQQVDDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFESSQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEATVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDLAGNVESVSKAKANLEKICRTLEDQLSEARGKNEEIQRSMSELTMQKSRLQTEAGELSRQLEEKESTVSQLSRSKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQAEVEDLMVDVDRANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEAALKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKMAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRIKKKMEGDLNEIEIQLSHANRQAAETLKHLRGVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRASLLQAEVEELRASLEQTERARKLAEQELLDANERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKATTDKEQDTSAHLERMKKNLEQTVKDLQHRRGEQLALKGGKKQIQKLEARIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQAKDRKNVLRLQDLVDKLQAKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE", "length": 1928, "header": "tr|A0A5G2QYU9-1|A0A5G2QYU9_PIG Isoform 1 of Myosin heavy chain 3 OS=Sus scrofa OX=9823 GN=MYH3 PE=1 SV=2 CANONICAL=A0A5G2QYU9-1" }, "locus": { "chromosome": "12", "start_pos": 55371900, "end_pos": 55351270, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076604.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076604.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063405.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063405.2" } ] } }, { "isoform_ac": "F1SS61-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9/entry#F1SS61-1", "sequence": { "sequence": "MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSTQDGKVTVETEDNRAHRAPFPFQTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPFDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVLKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKEELAKSEAKRKELEEKMVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEEDKVNSLSKIKSKLEQQVDDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFESSQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEATVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDLAGNVESVSKAKANLEKICRTLEDQLSEARGKNEEIQRSMSELTMQKSRLQTEAGELSRQLEEKESTVSQLSRSKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQAEVEDLMVDVDRANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEAALKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKMAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRIKKKMEGDLNEIEIQLSHANRQAAETLKHLRGVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRASLLQAEVEELRASLEQTERARKLAEQELLDANERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKATTDAAMMAEELKKEQDTSAHLERMKKNLEQTQLALKGGKKQIQKLEARIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQAKDRKNVLRLQDLVDKLQAKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQNNLKDNQRNLSTEIMMEEKTEETEEGDRVTHF", "length": 1945, "header": "tr|F1SS61-1|F1SS61_PIG Computationally mapped isoform of Myosin heavy chain 3 OS=Sus scrofa OX=9823 GN=MYH3 PE=1 SV=3 CANONICAL=A0A5G2QYU9-1" }, "locus": { "chromosome": "12", "start_pos": 55371900, "end_pos": 55347090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019601.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019601.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019082.4", "url": "https://www.ensembl.org/id/ENSSSCP00000019082.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTZ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTZ6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-390522", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-390522", "resource": "Reactome", "description": "Striated Muscle Contraction" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "myosin filament", "id": "GO:0032982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" }, { "name": "myofibril", "id": "GO:0030016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030016", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" }, { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "muscle system process", "id": "GO:0003012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003012", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" }, { "name": "muscle contraction", "id": "GO:0006936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006936", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" }, { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" }, { "name": "ATP metabolic process", "id": "GO:0046034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046034", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYU9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1721, "end_pos": 1723, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 677, "end_pos": 679, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 727, "end_pos": 729, "annotation": "n_glycosylation_sequon" }, { "start_pos": 978, "end_pos": 980, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" }, { "id": "PS51844", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51844" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin N-terminal SH3-like", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 82, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QYU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYU9" }, { "id": "PS51456", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51456" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin motor", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 779, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1721, "end_pos": 1723 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 603, "end_pos": 605 }, { "start_pos": 677, "end_pos": 679 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 727, "end_pos": 729 }, { "start_pos": 978, "end_pos": 980 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R5L5-1", "uniprot_ac": "A0A5G2R5L5", "uniprot_id": "A0A5G2R5L5_PIG", "mass": { "chemical_mass": 107174.0, "monoisotopic_mass": 107174.0 }, "refseq": {}, "gene_names": [ { "name": "NR3C2", "type": "recommended", "evidence": [ { "id": "A0A5G2R5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ] } ], "protein_names": [ { "name": "Mineralocorticoid receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5/entry#names_and_taxonomy" } ] }, { "name": "Nuclear receptor subfamily 3 group C member 2", "type": "synonym", "evidence": [ { "id": "A0A5G2R5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5#function" }, { "database": "UniProtKB", "id": "ARBA00037128", "url": "https://www.uniprot.org/uniprotkb/ARBA00037128#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NR3C2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5", "locus": { "chromosome": "8", "start_pos": 80668412, "end_pos": 80312234, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037766", "url": "https://www.ensembl.org/id/ENSSSCG00000037766" } ] } } ], "crossref": [ { "id": "A0A5G2R5L5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5L5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000037766", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037766", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07075", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07075", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07172", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07172", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3371497", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371497", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4090294", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4090294", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QUY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METKGYHSLPEGLEMERRWGQASETVERSSLGPTERTDESNYMEIVNVSCVSGAIPNNSTQGSSKEKHELLPCLQQDNNRPGILTSDIKTELESKELSATVAESMGLYMDSVRDADYSYDQQHPQGSASPAKIYQNVEQLVKFYKENGHRPSTLGGVSRPLRPFMPDSGSLVNGGVMRAVVKSPILCHEKSPSVCSPLNMTSAGCSPAGMGSVSSSSASFGSFGVHSPLTQGTPLTCSPNVENRGSRSHSPAHASNVGSPLSSPLSSMKSPISSPPSHCSVKSPVASPNNITLRSSVSSPANINNSRCSVSSPSNTNNRSSLSSPSASTVGSICSPISNAFSYSASGTPAGSVRDVVPSPDTHEKGAQEAPFPKTEETESAIPNGVTGQLNIVQYIKPEPDGAFSSSCLGGNSKINADSPFSVPIKQESTKHSCSGTSFKGNPTVNPFPFMDGSYFSFMDDKDYYSLSGILGPPVPGFDGNCEGSGFPMGIKQEPDDGSYYPEASIPSSAIVGVNSGGQSFHYRIGAQGTISLSRSARDQSFQHLSSFPPVNTLVESWKSHGDLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGKCSWQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQSQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVNSALVPQLSTISRALTPSPSMVLETIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTRCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESQALKVEFPAMLVEIISDQLPKVESGNAKTLYFHRK", "length": 986, "header": "tr|A0A5G2R5L5-1|A0A5G2R5L5_PIG Isoform 1 of Mineralocorticoid receptor OS=Sus scrofa OX=9823 GN=NR3C2 PE=3 SV=2 CANONICAL=A0A5G2R5L5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5/entry#A0A5G2QUY0-1", "sequence": { "sequence": "METKGYHSLPEGLEMERRWGQASETVERSSLGPTERTDESNYMEIVNVSCVSGAIPNNSTQGSSKEKHELLPCLQQDNNRPGILTSDIKTELESKELSATVAESMGLYMDSVRDADYSYDQQHPQGSASPAKIYQNVEQLVKFYKENGHRPSTLGGVSRPLRPFMPDSGSLVNGGVMRAVVKSPILCHEKSPSVCSPLNMTSAGCSPAGMGSVSSSSASFGSFGVHSPLTQGTPLTCSPNVENRGSRSHSPAHASNVGSPLSSPLSSMKSPISSPPSHCSVKSPVASPNNITLRSSVSSPANINNSRCSVSSPSNTNNRSSLSSPSASTVGSICSPISNAFSYSASGTPAGSVRDVVPSPDTHEKGAQEAPFPKTEETESAIPNGVTGQLNIVQYIKPEPDGAFSSSCLGGNSKINADSPFSVPIKQESTKHSCSGTSFKGNPTVNPFPFMDGSYFSFMDDKDYYSLSGILGPPVPGFDGNCEGSGFPMGIKQEPDDGSYYPEASIPSSAIVGVNSGGQSFHYRIGAQGTISLSRSARDQSFQHLSSFPPVNTLVESWKSHGDLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLGGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTRCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESQALKVEFPAMLVEIISDQLPKVESGNAKTLYFHRK", "length": 865, "header": "tr|A0A5G2QUY0-1|A0A5G2R5L5_PIG Computationally mapped isoform of Mineralocorticoid receptor OS=Sus scrofa OX=9823 GN=NR3C2 PE=3 SV=1 CANONICAL=A0A5G2R5L5-1" }, "locus": { "chromosome": "8", "start_pos": 80666758, "end_pos": 80312234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081679.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081679.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065767.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065767.1" } ] } }, { "isoform_ac": "A0A5G2R5L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5/entry#A0A5G2R5L5-1", "sequence": { "sequence": "METKGYHSLPEGLEMERRWGQASETVERSSLGPTERTDESNYMEIVNVSCVSGAIPNNSTQGSSKEKHELLPCLQQDNNRPGILTSDIKTELESKELSATVAESMGLYMDSVRDADYSYDQQHPQGSASPAKIYQNVEQLVKFYKENGHRPSTLGGVSRPLRPFMPDSGSLVNGGVMRAVVKSPILCHEKSPSVCSPLNMTSAGCSPAGMGSVSSSSASFGSFGVHSPLTQGTPLTCSPNVENRGSRSHSPAHASNVGSPLSSPLSSMKSPISSPPSHCSVKSPVASPNNITLRSSVSSPANINNSRCSVSSPSNTNNRSSLSSPSASTVGSICSPISNAFSYSASGTPAGSVRDVVPSPDTHEKGAQEAPFPKTEETESAIPNGVTGQLNIVQYIKPEPDGAFSSSCLGGNSKINADSPFSVPIKQESTKHSCSGTSFKGNPTVNPFPFMDGSYFSFMDDKDYYSLSGILGPPVPGFDGNCEGSGFPMGIKQEPDDGSYYPEASIPSSAIVGVNSGGQSFHYRIGAQGTISLSRSARDQSFQHLSSFPPVNTLVESWKSHGDLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGKCSWQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQSQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVNSALVPQLSTISRALTPSPSMVLETIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTRCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESQALKVEFPAMLVEIISDQLPKVESGNAKTLYFHRK", "length": 986, "header": "tr|A0A5G2R5L5-1|A0A5G2R5L5_PIG Isoform 1 of Mineralocorticoid receptor OS=Sus scrofa OX=9823 GN=NR3C2 PE=3 SV=2 CANONICAL=A0A5G2R5L5-1" }, "locus": { "chromosome": "8", "start_pos": 80666758, "end_pos": 80312234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084768.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084768.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071615.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071615.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 348, "start_aa": "Thr", "end_pos": 348, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr348", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUY0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3371497", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371497", "resource": "Reactome", "description": "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" }, { "id": "R-SSC-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" }, { "id": "R-SSC-4090294", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4090294", "resource": "Reactome", "description": "SUMOylation of intracellular receptors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "steroid binding", "id": "GO:0005496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005496", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "estrogen response element binding", "id": "GO:0034056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034056", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "TBP-class protein binding", "id": "GO:0017025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017025", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "nuclear receptor-mediated steroid hormone signaling pathway", "id": "GO:0030518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030518", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5L5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 914, "end_pos": 916, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R5L5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 986, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R5L5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5L5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" }, { "id": "PS51843", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51843" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NR LBD", "eco_id": "ECO_0000259", "start_pos": 728, "end_pos": 966, "start_aa": "Gln", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5L5" }, { "id": "PS51030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nuclear receptor", "eco_id": "ECO_0000259", "start_pos": 598, "end_pos": 677, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 348 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 47, "end_pos": 49 }, { "start_pos": 57, "end_pos": 59 }, { "start_pos": 581, "end_pos": 583 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 914, "end_pos": 916 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R5W7-1", "uniprot_ac": "A0A5G2R5W7", "uniprot_id": "A0A5G2R5W7_PIG", "mass": { "chemical_mass": 37655.0, "monoisotopic_mass": 37655.0 }, "refseq": {}, "gene_names": [ { "name": "DECR1", "type": "recommended", "evidence": [ { "id": "A0A5G2R5W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7" } ] } ], "protein_names": [ { "name": "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A5G2R5W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7/entry#names_and_taxonomy" } ] }, { "name": "1.3.1.124", "type": "synonym", "evidence": [ { "id": "A0A5G2R5W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7/entry#names_and_taxonomy" } ] }, { "name": "2,4-dienoyl-CoA reductase [NADPH]", "type": "synonym", "evidence": [ { "id": "A0A5G2R5W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U5Q1#function" }, { "database": "UniProtKB", "id": "ARBA00056513", "url": "https://www.uniprot.org/uniprotkb/ARBA00056513#function" }, { "database": "UniProtKB", "id": "A0A5G2R5W7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5W7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DECR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7", "locus": { "chromosome": "4", "start_pos": 46731360, "end_pos": 46767422, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006126", "url": "https://www.ensembl.org/id/ENSSSCG00000006126" } ] } } ], "crossref": [ { "id": "A0A5G2R5W7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5W7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006126", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006126", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05369", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05369", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR43658", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43658", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43658:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43658:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-77288", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "44912", "url": "https://www.rhea-db.org/rhea/44912", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45912", "url": "https://www.rhea-db.org/rhea/45912", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "61892", "url": "https://www.rhea-db.org/rhea/61892", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QV44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QV44-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5W7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1U5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U5Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1U5Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U5Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLGRVFAPGHGPRRVRRRWDGPGSRATLASTLSRFFTYGTKILYQSTEAFPSKSFPPFQKVMLPPNTFQGKLAFITGGGTGIGKRMTTHLSSLGAQCVIASRNIDILKATAEEISSQTGNKVHAIQCDVRDPNMVQNTVSELIKVIGHPDIVINNAAGNFISPSERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLAITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWSKYGMRFNVIQPGPIKTKGAFSRLDPTGAFEKEMIDRIPCGRLGTVEELANLATFLCSDYASWINGATIRFDGGEQVLLSGEFNHLRKVTKEQWDTIEGLIRKTKGS", "length": 348, "header": "tr|A0A5G2R5W7-1|A0A5G2R5W7_PIG Isoform 1 of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Sus scrofa OX=9823 GN=DECR1 PE=1 SV=1 CANONICAL=A0A5G2R5W7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QV44-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7/entry#A0A5G2QV44-1", "sequence": { "sequence": "MALLGRVFAPGHGPRRFFTYGTKILYQSTEAFPSKSFPPFQKVMLPPNTFQGKLAFITGGGTGIGKRMTTHLSSLGAQCVIASRNIDILKATAEEISSQTGNKVHAIQCDVRDPNMVQNTVSELIKVIGHPDIVINNAAGNFISPSERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKESLLFILIFRSLAAEWSKYGMRFNVIQPGPIKTKGAFSRLDPTGAFEKEMIDRIPCGRLGTVEELANLATFLCSDYASWINGATIRFDGGEQVLLSGEFNHLRKVTKEQWDTIEGLIRKTKGS", "length": 304, "header": "tr|A0A5G2QV44-1|A0A5G2R5W7_PIG Computationally mapped isoform of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Sus scrofa OX=9823 GN=DECR1 PE=1 SV=1 CANONICAL=A0A5G2R5W7-1" }, "locus": { "chromosome": "4", "start_pos": 46767393, "end_pos": 46732682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072160.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072160.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068005.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068005.1" } ] } }, { "isoform_ac": "A0A5G2R5W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7/entry#A0A5G2R5W7-1", "sequence": { "sequence": "MALLGRVFAPGHGPRRVRRRWDGPGSRATLASTLSRFFTYGTKILYQSTEAFPSKSFPPFQKVMLPPNTFQGKLAFITGGGTGIGKRMTTHLSSLGAQCVIASRNIDILKATAEEISSQTGNKVHAIQCDVRDPNMVQNTVSELIKVIGHPDIVINNAAGNFISPSERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLAITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWSKYGMRFNVIQPGPIKTKGAFSRLDPTGAFEKEMIDRIPCGRLGTVEELANLATFLCSDYASWINGATIRFDGGEQVLLSGEFNHLRKVTKEQWDTIEGLIRKTKGS", "length": 348, "header": "tr|A0A5G2R5W7-1|A0A5G2R5W7_PIG Isoform 1 of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Sus scrofa OX=9823 GN=DECR1 PE=1 SV=1 CANONICAL=A0A5G2R5W7-1" }, "locus": { "chromosome": "4", "start_pos": 46767393, "end_pos": 46732682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083660.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083660.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069535.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069535.1" } ] } }, { "isoform_ac": "A0A5K1U5Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7/entry#A0A5K1U5Q1-1", "sequence": { "sequence": "HNLLGLIFILTHFFTYGTKILYQSTEAFPSKSFPPFQKVMLPPNTFQGKLAFITGGGTGIGKRMTTHLSSLGAQCVIASRNIDILKATAEEISSQTGNKVHAIQCDVRDPNMVQNTVSELIKVIGHPDIVINNAAGNFISPSERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLAITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWSKYGMRFNVIQPGPIKTKGAFSRLDPTGAFEKEMIDRIPCGRLGTVEELANLATFLCSDYASWINGATIRFDGGEQVLLSGEFNHLRKVTKEQWDTIEGLIRKTKGS", "length": 324, "header": "tr|A0A5K1U5Q1-1|A0A5G2R5W7_PIG Computationally mapped isoform of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Sus scrofa OX=9823 GN=DECR1 PE=1 SV=2 CANONICAL=A0A5G2R5W7-1" }, "locus": { "chromosome": "4", "start_pos": 46753355, "end_pos": 46732682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006718.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006718.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006535.5", "url": "https://www.ensembl.org/id/ENSSSCP00000006535.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QV44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV44" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-77288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77288", "resource": "Reactome", "description": "mitochondrial fatty acid beta-oxidation of unsaturated fatty acids" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5W7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7" } ], "pmid": "" }, { "name": "2,4-dienoyl-CoA reductase (NADPH) activity", "id": "GO:0008670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008670", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5W7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5W7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7" } ], "pmid": "" }, { "name": "NADPH binding", "id": "GO:0070402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070402", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5W7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5W7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7" } ], "pmid": "" }, { "name": "catalytic complex", "id": "GO:1902494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902494", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5W7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5W7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7" } ], "pmid": "" }, { "name": "positive regulation of cold-induced thermogenesis", "id": "GO:0120162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120162", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5W7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5W7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "44912", "name": "", "equation": "(2E,4E)-hexadienoyl-CoA + NADPH + H(+) = (3E)-hexenoyl-CoA + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "44912", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44912" } ] }, { "id": "45912", "name": "", "equation": "a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "45912", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45912" } ] }, { "id": "61892", "name": "", "equation": "a (2E,4Z)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "61892", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61892" } ] }, { "id": "R-SSC-109343", "name": "Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-109990" ], "output_participant_list": [ "R-ALL-109994" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-109343", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-109343" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-109990", "participant_name": "2-trans-4-cis-decadienoyl-CoA [mitochondrial matrix]", "crossref": [ { "id": "137593", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-109994", "participant_name": "3-trans-decenoyl-CoA [mitochondrial matrix]", "crossref": [ { "id": "ZINC000096061868", "database": "ZINC", "url": "" }, { "id": "84793", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R5W7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 348, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R5W7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5W7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1A0-1", "uniprot_ac": "A0A5G2R1A0", "uniprot_id": "A0A5G2R1A0_PIG", "mass": { "chemical_mass": 169389.0, "monoisotopic_mass": 169389.0 }, "refseq": {}, "gene_names": [ { "name": "ARHGEF11", "type": "recommended", "evidence": [ { "id": "A0A5G2R1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 11", "type": "recommended", "evidence": [ { "id": "A0A5G2R1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW79#function" }, { "database": "UniProtKB", "id": "ARBA00057618", "url": "https://www.uniprot.org/uniprotkb/ARBA00057618#function" }, { "database": "UniProtKB", "id": "A0A5G2R0Y8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Y8#function" }, { "database": "UniProtKB", "id": "A0A5G2R1A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0#function" }, { "database": "UniProtKB", "id": "A0A5G2RID9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RID9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARHGEF11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0", "locus": { "chromosome": "4", "start_pos": 93160084, "end_pos": 93046770, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006461", "url": "https://www.ensembl.org/id/ENSSSCG00000006461" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006461", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006461", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08753", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08753", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13391", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13391", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23069", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23069", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157291", "url": "https://www.ncbi.nlm.nih.gov/gene/100157291", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037803", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037803", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45872:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45872:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09128", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09128", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17838", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17838", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-416572", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416572", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013026", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013026", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QW79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW79-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0Y8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RID9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RID9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RID9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RID9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVRLPQSIDRLSSLSLGDSAPERKSPSHHRQPSDTSETAGLVQRCVIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLLGSSPSSVGVSGLQQDPAPAGAPRVTPVVPPPPPPPPLPPPQRITGPKPLQRICEVYSRNPASLLEEQIEGARRRVTQLQLKIQQETGGLVDILPLYGDTSQRSSEGRLSLDSQEGDSGLDSGTERFPSLSESLMNRNSILSDPGLDSPRTSPVIMARMAQHHRRQGSDAPLLPSSDQGVDQSPKPLIIGPEEDYDPGYFNNESDIVFQDFEKLKSRPAHLGVFLRYIFSQADPGPLLFYLCAEVYQQTNPKDSRSLGKDIWNIFLEKNAPLRVKVPEMLQAEIDLRLRSGEDVRAVLCEAQEAAMPDIQEQIQDYRTKRTLGLGSLYGENDLLDLDGDPLRERQVAEKQLAALGDILSKYEEDRSAPMDFALNTYMSHAGIRLRETRPSNAAEKAQSAPDKDKWLPFFPKTKKSSNSKKEKDALEDKKRNPILKYIGKPKGSSQSTFHIPLSPVEVKPGNVRNIIQHFENNQQYDAPEPGTQRLSTGSFPEDLLESDSSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEAARLHQSASSSASSLSTRSLENPTPPFTPKMGRRSIESPSLGFCTDALLPNLLEDDLGHLSDLEPEPDAQNWQHTVGKDVVAGLSQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEGLLPREELARLFPNLPELIEIHNSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTRQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLENIIKHTEGGTTEHEKLCRARDQCREILKYVNEAVKQTENRHRLESYQKRLDTTSLERASNPLAAEFKSLDLTARKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLIRSVATDKRAFFIICTSELGPPQIYELVALTSSDKNTWMELLEEAVRNATRHPGAAPTPVHPPPPGPQEPAHQSPTPSRVELDDSEVFRSGPEPEAVPGGPGPQQRIKGKHPALLEDPEQEGSREEEELGALPDPSTSPDREKRGSRTRDPILRPLPGPLFMEGLADAALEDVENLRQLILWSLLPGHPMDPQAAGEPEDDLTPTPSVISITSHPWDPGSPGRAPPGGEGDNAQLSGPERGQPGQEDVALRSLEHLPPRTRNSGIWESPDLDRNPEEEASSTEATGSYKVVRKAEVAGSKVVPELPECGQSEPEPPEVEGGAEATGNCFYVSMPAGPPDSSTDSLGARRSPSQPDGLPAWQTEPRPPPRGGSGDQRHPGHSPPSLALRDVGMIFRTIEQLTLKLSRLKDMELAHRELLRSLGGESSGGTTPVGSFHTEPTRWTDSSLSPPAKEPPASDSRDSHEMGPCPEDGPSTLQEAGAADTATSPGL", "length": 1537, "header": "tr|A0A5G2R1A0-1|A0A5G2R1A0_PIG Isoform 1 of Rho guanine nucleotide exchange factor 11 OS=Sus scrofa OX=9823 GN=ARHGEF11 PE=4 SV=2 CANONICAL=A0A5G2R1A0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QW79-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0/entry#A0A5G2QW79-1", "sequence": { "sequence": "MSVRLPQSIDRLSSLSLGDSAPERKSPSHHRQPSDTSETAGLVQRCVIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLLGSSPSSVGVSGLQQDPAPAGAPRVTPVVPPPPPPPPLPPPQRITGPKPLQDILPLYGDTSQRSSEGRLSLDSQEGDSGLDSGTERFPSLSESLMNRNSILSDPGLDSPRTSPVIMARMAQHHRRQGSDAPLLPSSDQGVDQSPKPLIIGPEEDYDPGYFNNESDIVFQDFEKLKSRPAHLGVFLRYIFSQADPGPLLFYLCAEVYQQTNPKDSRSLGKDIWNIFLEKNAPLRVKVPEMLQAEIDLRLRSGEDVRAVLCEAQEAAMPDIQEQIQDYRTKRTLGLGSLYGENDLLDLDGDPLRERQVAEKQLAALGDILSKYEEDRSAPMDFALNTYMSHAGIRLRETRPSNAAEKAQSAPDKDKWLPFFPKTKKSSNSKKEKDALEDKKRNPILKYIGKPKGSSQSTFHIPLSPVEVKPGNVRNIIQHFENNQQYDAPEPGTQRLSTGSFPEDLLESDSSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEAARLHQSASSSASSLSTRSLENPTPPFTPKMGRRSIESPSLGFCTDALLPNLLEDDLGHLSDLEPEPDAQNWQHTVGKDVVAGLSQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEGLLPREELARLFPNLPELIEIHNSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTRQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLENIIKHTEGGTTEHEKLCRARDQCREILKYVNEAVKQTENRHRLESYQKRLDTTSLERASNPLAAEFKSLDLTARKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLIRSVATDKRAFFIICTSELGPPQIYELVALTSSDKNTWMELLEEAVRNATRHPGAAPTPVHPPPPGPQEPAHQSPTPSRVELDDSEVFRSGPEPEAVPGGPGPQQRIKGKHPALLEDPEQEGSREEEELGALPDPSTSPDREKRGSRTRDPILRPLPGPLFMEGLADAALEDVENLRQLILWSLLPGHPMDPQAAGEPEDDLTPTPSVISITSHPWDPGSPGRAPPGGEGDNAQLSGPERGQPGQEDVALRSLEHLPPRTRNSGIWESPDLDRNPEEEASSTEATGSYKVVRKAEVAGSKVVPELPECGQSEPEPPEVEGGAEATGNCFYVSMPAGPPDSSTDSLGARRSPSQPDGLPAWQTEPRPPPRGGSGDQRHPGHSPPSLALRDVGMIFRTIEQLTLKLSRLKDMELAHRELLRSLGGESSGGTTPVGSFHTEPTRWTDSSLSPPAKEPPASDSRDSHEMGPCPEDGPSTLQEAGAADTATSPGL", "length": 1497, "header": "tr|A0A5G2QW79-1|A0A5G2R1A0_PIG Computationally mapped isoform of Rho guanine nucleotide exchange factor 11 OS=Sus scrofa OX=9823 GN=ARHGEF11 PE=4 SV=2 CANONICAL=A0A5G2R1A0-1" }, "locus": { "chromosome": "4", "start_pos": 93159620, "end_pos": 93047038, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075293.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075293.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068410.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068410.2" } ] } }, { "isoform_ac": "A0A5G2R0Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0/entry#A0A5G2R0Y8-1", "sequence": { "sequence": "MSVRLPQSIDRLSSLSLGDSAPERKSPSHHRQPSDTSETAGLVQRCVIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLLGSSPSSVGVSGLQQDPAPAGAPRVTPVVPPPPPPPPLPPPQRITGPKPLQDPEFQKHATQILRNMLRQEEKELQDILPLYGDTSQRSSEGRLSLDSQEGDSGLDSGTERFPSLSESLMNRNSILSDPGLDSPRTSPVIMARMAQHHRRQGSDAPLLPSSDQGVDQSPKPLIIGPEEDYDPGYFNNESDIVFQDFEKLKSRPAHLGVFLRYIFSQADPGPLLFYLCAEVYQQTNPKDSRSLGKDIWNIFLEKNAPLRVKVPEMLQAEIDLRLRSGEDVRAVLCEAQEAAMPDIQEQIQDYRTKRTLGLGSLYGENDLLDLDGDPLRERQVAEKQLAALGDILSKYEEDRSAPMDFALNTYMSHAGIRLRETRPSNAAEKAQSAPDKDKWLPFFPKTKKSSNSKKEKDALEDKKRNPILKYIGKPKGSSQSTFHIPLSPVEVKPGNVRNIIQHFENNQQYDAPEPGTQRLSTGSFPEDLLESDSSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEAARLHQSASSSASSLSTRSLENPTPPFTPKMGRRSIESPSLGFCTDALLPNLLEDDLGHLSDLEPEPDAQNWQHTVGKDVVAGLSQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEGLLPREELARLFPNLPELIEIHNSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTRQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLENIIKHTEGGTTEHEKLCRARDQCREILKYVNEAVKQTENRHRLESYQKRLDTTSLERASNPLAAEFKSLDLTARKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLIRSVATDKRAFFIICTSELGPPQIYELVALTSSDKNTWMELLEEAVRNATRHPGAAPTPVHPPPPGPQEPAHQSPTPSRVELDDSEVFRSGPEPEAVPGGPGPQQRIKGKHPALLEDPEQEGSREEEELGALPDPSTSPDREKRGSRTRDPILRPLPGPLFMEGLADAALEDVENLRQLILWSLLPGHPMDPQAAGEPEDDLTPTPSVISITSHPWDPGSPGRAPPGGEGDNAQLSGPERGQPGQEDVALRSLEHLPPRTRNSGIWESPDLDRNPEEEASSTEATGSYKVVRKAEVAGSKVVPELPECGQSEPEPPEVEGGAEATGNCFYVSMPAGPPDSSTDSLGARRSPSQPDGLPAWQTEPRPPPRGGSGDQRHPGHSPPSLALRDVGMIFRTIEQLTLKLSRLKDMELAHRELLRSLGGESSGGTTPVGSFHTEPTRWTDSSLSPPAKEPPASDSRDSHEMGPCPEDGPSTLQEAGAADTATSPGL", "length": 1521, "header": "tr|A0A5G2R0Y8-1|A0A5G2R0Y8_PIG Computationally mapped isoform of Rho guanine nucleotide exchange factor 11 OS=Sus scrofa OX=9823 GN=ARHGEF11 PE=4 SV=2 CANONICAL=A0A5G2R1A0-1" }, "locus": { "chromosome": "4", "start_pos": 93159620, "end_pos": 93047038, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087379.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087379.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070830.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070830.2" } ] } }, { "isoform_ac": "A0A5G2R1A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0/entry#A0A5G2R1A0-1", "sequence": { "sequence": "MSVRLPQSIDRLSSLSLGDSAPERKSPSHHRQPSDTSETAGLVQRCVIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLLGSSPSSVGVSGLQQDPAPAGAPRVTPVVPPPPPPPPLPPPQRITGPKPLQRICEVYSRNPASLLEEQIEGARRRVTQLQLKIQQETGGLVDILPLYGDTSQRSSEGRLSLDSQEGDSGLDSGTERFPSLSESLMNRNSILSDPGLDSPRTSPVIMARMAQHHRRQGSDAPLLPSSDQGVDQSPKPLIIGPEEDYDPGYFNNESDIVFQDFEKLKSRPAHLGVFLRYIFSQADPGPLLFYLCAEVYQQTNPKDSRSLGKDIWNIFLEKNAPLRVKVPEMLQAEIDLRLRSGEDVRAVLCEAQEAAMPDIQEQIQDYRTKRTLGLGSLYGENDLLDLDGDPLRERQVAEKQLAALGDILSKYEEDRSAPMDFALNTYMSHAGIRLRETRPSNAAEKAQSAPDKDKWLPFFPKTKKSSNSKKEKDALEDKKRNPILKYIGKPKGSSQSTFHIPLSPVEVKPGNVRNIIQHFENNQQYDAPEPGTQRLSTGSFPEDLLESDSSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEAARLHQSASSSASSLSTRSLENPTPPFTPKMGRRSIESPSLGFCTDALLPNLLEDDLGHLSDLEPEPDAQNWQHTVGKDVVAGLSQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEGLLPREELARLFPNLPELIEIHNSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTRQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLENIIKHTEGGTTEHEKLCRARDQCREILKYVNEAVKQTENRHRLESYQKRLDTTSLERASNPLAAEFKSLDLTARKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLIRSVATDKRAFFIICTSELGPPQIYELVALTSSDKNTWMELLEEAVRNATRHPGAAPTPVHPPPPGPQEPAHQSPTPSRVELDDSEVFRSGPEPEAVPGGPGPQQRIKGKHPALLEDPEQEGSREEEELGALPDPSTSPDREKRGSRTRDPILRPLPGPLFMEGLADAALEDVENLRQLILWSLLPGHPMDPQAAGEPEDDLTPTPSVISITSHPWDPGSPGRAPPGGEGDNAQLSGPERGQPGQEDVALRSLEHLPPRTRNSGIWESPDLDRNPEEEASSTEATGSYKVVRKAEVAGSKVVPELPECGQSEPEPPEVEGGAEATGNCFYVSMPAGPPDSSTDSLGARRSPSQPDGLPAWQTEPRPPPRGGSGDQRHPGHSPPSLALRDVGMIFRTIEQLTLKLSRLKDMELAHRELLRSLGGESSGGTTPVGSFHTEPTRWTDSSLSPPAKEPPASDSRDSHEMGPCPEDGPSTLQEAGAADTATSPGL", "length": 1537, "header": "tr|A0A5G2R1A0-1|A0A5G2R1A0_PIG Isoform 1 of Rho guanine nucleotide exchange factor 11 OS=Sus scrofa OX=9823 GN=ARHGEF11 PE=4 SV=2 CANONICAL=A0A5G2R1A0-1" }, "locus": { "chromosome": "4", "start_pos": 93159620, "end_pos": 93047038, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077539.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077539.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070135.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070135.2" } ] } }, { "isoform_ac": "A0A5G2RID9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0/entry#A0A5G2RID9-1", "sequence": { "sequence": "MSVRLPQSIDRLSSLSLGDSAPERKSPSHHRQPSDTSETAGLVQRCVIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLLGSSPSSVGVSGLQQDPAPAGAPRVTPVVPPPPPPPPLPPPQRITGPKPLQDPEFQKHATQILRNMLRQEEKELQRICEVYSRNPASLLEEQIEGARRRVTQLQLKIQQETGGLVDILPLYGDTSQRSSEGRLSLDSQEGDSGLDSGTERFPSLSESLMNRNSILSDPGLDSPRTSPVIMARMAQHHRRQGSDAPLLPSSDQGVDQSPKPLIIGPEEDYDPGYFNNESDIVFQDFEKLKSRPAHLGVFLRYIFSQADPGPLLFYLCAEVYQQTNPKDSRSLGKDIWNIFLEKNAPLRVKVPEMLQAEIDLRLRSGEDVRAVLCEAQEAAMPDIQEQIQDYRTKRTLGLGSLYGENDLLDLDGDPLRERQVAEKQLAALGDILSKYEEDRSAPMDFALNTYMSHAGIRLRETRPSNAAEKAQSAPDKDKWLPFFPKTKKSSNSKKEKDALEDKKRNPILKYIGKPKGSSQSIKPGNVRNIIQHFENNQQYDAPEPGTQRLSTGSFPEDLLESDSSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEAARLHQSASSSASSLSTRSLENPTPPFTPKMGRRSIESPSLGFCTDALLPNLLEDDLGHLSDLEPEPDAQNWQHTVGKDVVAGLSQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEGLLPREELARLFPNLPELIEIHNSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTRQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLENIIKHTEGGTTEHEKLCRARDQCREILKYVNEAVKQTENRHRLESYQKRLDTTSLERASNPLAAEFKSLDLTARKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLIRSVATDKRAFFIICTSELGPPQIYELVALTSSDKNTWMELLEEAVRNATRHPGAAPTPVHPPPPGPQEPAHQSPTPSRVELDDSEVFRSGPEPEAVPGGPGPQQRIKGKHPALLEDPEQEGSREEEELGALPDPSTSPDREKRGSRTRDPILRPLPGPLFMEGLADAALEDVENLRQLILWSLLPGHPMDPQAAGEPEDDLTPTPSVISITSHPWDPGSPGRAPPGGEGDNAQLSGPERGQPGQEDVALRSLEHLPPRTRNSGIWESPDLDRNPEEEASSTEATGSYKVVRKGNCFYVSMPAGPPDSSTDSLGARRSPSQPDGLPAWQTEPRPPPRGGSGDQRHPGHSPPSLALRDVGMIFRTIEQLTLKLSRLKDMELAHRELLRSLGGESSGGTTPVGSFHTEPTRWTDSSLSPPAKEPPASDSRDSHEMGPCPEDGPSTLQEAGAADTATSPGL", "length": 1519, "header": "tr|A0A5G2RID9-1|A0A5G2RID9_PIG Computationally mapped isoform of Rho guanine nucleotide exchange factor 11 OS=Sus scrofa OX=9823 GN=ARHGEF11 PE=4 SV=1 CANONICAL=A0A5G2R1A0-1" }, "locus": { "chromosome": "4", "start_pos": 93159620, "end_pos": 93047038, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079334.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079334.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071337.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071337.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1105, "start_aa": "Thr", "end_pos": 1105, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1105", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1123, "start_aa": "Thr", "end_pos": 1123, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1123", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1252, "start_aa": "Thr", "end_pos": 1252, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1252", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW79" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-SSC-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-SSC-416572", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416572", "resource": "Reactome", "description": "Sema4D induced cell migration and growth-cone collapse" }, { "id": "R-SSC-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-SSC-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-SSC-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" } ], "pmid": "" }, { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" } ], "pmid": "" }, { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1095, "end_pos": 1097, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 749, "end_pos": 938, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 110, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1A0" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 980, "end_pos": 1094, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1105, 1123, 1252 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1095, "end_pos": 1097 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 92, "end_pos": 94 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWF0-1", "uniprot_ac": "A0A5G2QWF0", "uniprot_id": "A0A5G2QWF0_PIG", "mass": { "chemical_mass": 15632.0, "monoisotopic_mass": 15632.0 }, "refseq": { "ac": "XP_003124792", "name": "V-type proton ATPase 16 kDa proteolipid subunit", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124792" }, "gene_names": [ { "name": "ATP6V0C", "type": "recommended", "evidence": [ { "id": "A0A5G2QWF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0" } ] }, { "name": "ATP6V0C", "type": "synonym", "evidence": [ { "id": "XP_003124792", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124792" } ] } ], "protein_names": [ { "name": "V-type proton ATPase proteolipid subunit", "type": "recommended", "evidence": [ { "id": "A0A5G2QWF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0/entry#names_and_taxonomy" } ] }, { "name": "V-type proton ATPase 16 kDa proteolipid subunit", "type": "synonym", "evidence": [ { "id": "XP_003124792", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124792" } ] } ], "function": [ { "annotation": "Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0#function" }, { "database": "UniProtKB", "id": "RU363060", "url": "https://www.uniprot.org/uniprotkb/RU363060#function" }, { "database": "UniProtKB", "id": "F1SUH8", "url": "https://www.uniprot.org/uniprotkb/F1SUH8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ATP6V0C", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0", "locus": {} } ], "crossref": [ { "id": "A0A5G2QWF0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008056", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008056", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18175", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18175", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18176", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18176", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100518959", "url": "https://www.ncbi.nlm.nih.gov/gene/100518959", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518959", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518959", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGVMKPD", "url": "https://omabrowser.org/oma/group/MGVMKPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QWF0", "url": "https://www.orthodb.org/?gene=A0A5G2QWF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10263", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10263", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1222556", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1222556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-77387", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77387", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-917977", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917977", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983712", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983712", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003124792", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124792", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QWF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SUH8", "url": "https://www.uniprot.org/uniprotkb/F1SUH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SUH8-1", "url": "https://www.uniprot.org/uniprotkb/F1SUH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEAKSGPEYAAFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTEGISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK", "length": 155, "header": "tr|A0A5G2QWF0-1|A0A5G2QWF0_PIG Isoform 1 of V-type proton ATPase proteolipid subunit OS=Sus scrofa OX=9823 GN=ATP6V0C PE=1 SV=1 CANONICAL=A0A5G2QWF0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0/entry#A0A5G2QWF0-1", "sequence": { "sequence": "MSEAKSGPEYAAFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTEGISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK", "length": 155, "header": "tr|A0A5G2QWF0-1|A0A5G2QWF0_PIG Isoform 1 of V-type proton ATPase proteolipid subunit OS=Sus scrofa OX=9823 GN=ATP6V0C PE=1 SV=1 CANONICAL=A0A5G2QWF0-1" }, "locus": { "chromosome": "3", "start_pos": 39538515, "end_pos": 39533231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071558.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071558.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068480.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068480.1" } ] } }, { "isoform_ac": "F1SUH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0/entry#F1SUH8-1", "sequence": { "sequence": "MSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTEGISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK", "length": 112, "header": "tr|F1SUH8-1|F1SUH8_PIG Computationally mapped isoform of V-type proton ATPase proteolipid subunit OS=Sus scrofa OX=9823 GN=ATP6V0C PE=3 SV=2 CANONICAL=A0A5G2QWF0-1" }, "locus": { "chromosome": "3", "start_pos": 39533691, "end_pos": 39533231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008828.5", "url": "https://www.ensembl.org/id/ENSSSCT00000008828.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008604.3", "url": "https://www.ensembl.org/id/ENSSSCP00000008604.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518959", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518959", "resource": "KEGG Pathway" }, { "id": "R-SSC-1222556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1222556", "resource": "Reactome", "description": "ROS and RNS production in phagocytes" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-77387", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77387", "resource": "Reactome", "description": "Insulin receptor recycling" }, { "id": "R-SSC-917977", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917977", "resource": "Reactome", "description": "Transferrin endocytosis and recycling" }, { "id": "R-SSC-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" }, { "id": "R-SSC-983712", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983712", "resource": "Reactome", "description": "Ion channel transport" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I2T6-1", "protein_name": "V-type proton ATPase proteolipid subunit", "gene_name": "Atp6v0c", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDIKNSPEYAAFFAVVGASSAMIFSAMGAAYGTAKSGTGIAAMSVMRPEMIMKSIIPVVMAGIIAIYGLVVAVLIANSLTDGITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK", "length": 155 }, "evidence": [ { "id": "A0A5G2QWF0", "url": "https://omabrowser.org/oma/group/A0A5G2QWF0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P0DH92-1", "protein_name": "V-type proton ATPase subunit c1", "gene_name": "VHA-c1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTFSGDETAPFFGFLGAAAALVFSCMGAAYGTAKSGVGVASMGVMRPELVMKSIVPVVMAGVLGIYGLIIAVIISTGINPKAKSYYLFDGYAHLSSGLACGLAGLSAGMAIGIVGDAGVRANAQQPKLFVGMILILIFAEALALYGLIVGIILSSRAGQSRAE", "length": 164 }, "evidence": [ { "id": "A0A5G2QWF0", "url": "https://omabrowser.org/oma/group/A0A5G2QWF0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DH93-1", "protein_name": "V-type proton ATPase subunit c3", "gene_name": "VHA-c3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTFSGDETAPFFGFLGAAAALVFSCMGAAYGTAKSGVGVASMGVMRPELVMKSIVPVVMAGVLGIYGLIIAVIISTGINPKAKSYYLFDGYAHLSSGLACGLAGLSAGMAIGIVGDAGVRANAQQPKLFVGMILILIFAEALALYGLIVGIILSSRAGQSRAE", "length": 164 }, "evidence": [ { "id": "A0A5G2QWF0", "url": "https://omabrowser.org/oma/group/A0A5G2QWF0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DH94-1", "protein_name": "V-type proton ATPase subunit c5", "gene_name": "VHA-c5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTFSGDETAPFFGFLGAAAALVFSCMGAAYGTAKSGVGVASMGVMRPELVMKSIVPVVMAGVLGIYGLIIAVIISTGINPKAKSYYLFDGYAHLSSGLACGLAGLSAGMAIGIVGDAGVRANAQQPKLFVGMILILIFAEALALYGLIVGIILSSRAGQSRAE", "length": 164 }, "evidence": [ { "id": "A0A5G2QWF0", "url": "https://omabrowser.org/oma/group/A0A5G2QWF0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P23380-1", "protein_name": "V-type proton ATPase 16 kDa proteolipid subunit c", "gene_name": "Vha16-1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSEVSSDNPIYGPFFGVMGAASAIIFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAGALEEPSKYSLYRGFIHLGAGLAVGFSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAIYLYTK", "length": 159 }, "evidence": [ { "id": "A0A5G2QWF0", "url": "https://omabrowser.org/oma/group/A0A5G2QWF0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P23956-1", "protein_name": "V-type proton ATPase 16 kDa proteolipid subunit c", "gene_name": "ATP6V0C", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSEAKNGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEMIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDGISLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK", "length": 155 }, "evidence": [ { "id": "A0A5G2QWF0", "url": "https://omabrowser.org/oma/group/A0A5G2QWF0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P25515-1", "protein_name": "V-type proton ATPase subunit c", "gene_name": "VMA3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTELCPVYAPFFGAIGCASAIIFTSLGAAYGTAKSGVGICATCVLRPDLLFKNIVPVIMAGIIAIYGLVVSVLVCYSLGQKQALYTGFIQLGAGLSVGLSGLAAGFAIGIVGDAGVRGSSQQPRLFVGMILILIFAEVLGLYGLIVALLLNSRATQDVVC", "length": 160 }, "evidence": [ { "id": "A0A5G2QWF0", "url": "https://omabrowser.org/oma/group/A0A5G2QWF0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P27449-1", "protein_name": "V-type proton ATPase 16 kDa proteolipid subunit c", "gene_name": "ATP6V0C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSESKSGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK", "length": 155 }, "evidence": [ { "id": "A0A5G2QWF0", "url": "https://omabrowser.org/oma/group/A0A5G2QWF0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54642-1", "protein_name": "V-type proton ATPase proteolipid subunit", "gene_name": "vatP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFQLLSFLLSGEATAVERIITDACPVYAPFFGAMGVTAALVFTVMGAAYGTAKASVGISNMGVMKPDLVIKAFIPVIFAGVIAIYGLIICVILVGGIKPNANYTLMKSFTDLGAGLTVGLCGLAAGMAIGIVGDSGVRAFGQQPKLYVIMMLILIFSEALGLYGLIIGILLSSVSDTYCPGQALVPLNSGNVIGKN", "length": 196 }, "evidence": [ { "id": "A0A5G2QWF0", "url": "https://omabrowser.org/oma/group/A0A5G2QWF0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0" } ], "pmid": "" }, { "name": "clathrin-coated vesicle membrane", "id": "GO:0030665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030665", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0" } ], "pmid": "" }, { "name": "proton-transporting V-type ATPase, V0 domain", "id": "GO:0033179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033179", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWF0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 155, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWF0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWF0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF0" }, { "id": "PF00137", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00137" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "V-ATPase proteolipid subunit C-like", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 76, "start_aa": "Met", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWF3-1", "uniprot_ac": "A0A5G2QWF3", "uniprot_id": "A0A5G2QWF3_PIG", "mass": { "chemical_mass": 138541.0, "monoisotopic_mass": 138541.0 }, "refseq": {}, "gene_names": [ { "name": "RRP12", "type": "recommended", "evidence": [ { "id": "A0A5G2QWF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3" } ] } ], "protein_names": [ { "name": "Ribosomal RNA processing 12 homolog", "type": "synonym", "evidence": [ { "id": "A0A5G2QWF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RRP12", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3", "locus": { "chromosome": "14", "start_pos": 108772175, "end_pos": 108805506, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010514", "url": "https://www.ensembl.org/id/ENSSSCG00000010514" } ] } } ], "crossref": [ { "id": "A0A5G2QWF3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWF3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010514", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010514", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48287", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48287", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48287:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48287:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08161", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08161", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25772", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25772", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QWF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRSGKLRSGVSAKLKRWKKGHSSESNPAICRHRQAARSRFFSPPSGKSNLTVDAVKLHNEMQSGSLRLGKSEAPETVMEEEEVAPALTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAAHKEICAVLAAVTEVIRSQGGKETETEYFAALMTTMEAVESTESLAAVAYLLNLVLKRVPSPVLIRKFSDTSKAFMDIMSAQASSGSTSALRWVSVWVSVSPLLSSRAHPTWLKLGGSPGGVLSCLATLLRKQDLEAWGYPVTLQVYQGLLSFTVHIKPKVRKAAQHGVCSVLKGSEIMFGEKAPAHHPAAIPTAKFCIQEIEKSGGSKEATTLLHMLTLLKDLLPCFPEGLVKSCSETLLRVMTLNHVLVSACAMQAFHSLFHAKPSPGTLPAELNAQIIKALYDYVPSENDLQPLLAWLKVMEKAHINLVRLHQNLGLGHLPRFFGTAMTCLLSPHSQVVTVAAQCLQEILRECVAPHMADIGSVTSSASGPAQYIAKMFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAALDHAVGAAVATMGPQVVLEAVPLEIDGSEETLDFPRSWLLPVIRDHVRETRLGFFTTYFLPLATTLKNKALDLAQAGSTVESKIYDTLQWQIWTLLPGFCTKPTDVATSFKGLARTLGTAISERPDLRVTVCQALRTLITKGCEAEADRAEVSRFAKNFLPILFNLYGQPVAAGDTPAPRRAVLETIKTYLTITEAQLVNGFLEKASEKVLDPASSDFTRLSVLDLVVALAPHADEAAISKLYSTIRPYLESKSHGIQKKAYRVLEEVCASPQGPGARFVQNHLDELKKTLLDSLRSTSSPAKRPRLKCLIHIVKKLSAEHEEFISALVPEVILCTKEVSVGARKNAFVLLVEMGHAFLRFGPSQEEALQRYLVLIYPGLVGAVTMVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVVVMDVVHLAKHVQLVMGAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKKLLPEEYHKVLVNIRKAEARAKKHRALNQAAVEEEEEEEEPVQGKGDSIEEILADSEDEDDEEERARSKEQRRLARQRSQAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGQKKDHGFKVSADGRLIIREEEDDDTAKAEEEEGAKGEDEEMADLMEDMGVRRKKHQKLKQQEADDEELEMPPQYQGEAAMLLSWSTGSCHLQ", "length": 1256, "header": "tr|A0A5G2QWF3-1|A0A5G2QWF3_PIG Isoform 1 of Ribosomal RNA processing 12 homolog OS=Sus scrofa OX=9823 GN=RRP12 PE=3 SV=1 CANONICAL=A0A5G2QWF3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3/entry#A0A5G2QWF3-1", "sequence": { "sequence": "MGRSGKLRSGVSAKLKRWKKGHSSESNPAICRHRQAARSRFFSPPSGKSNLTVDAVKLHNEMQSGSLRLGKSEAPETVMEEEEVAPALTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAAHKEICAVLAAVTEVIRSQGGKETETEYFAALMTTMEAVESTESLAAVAYLLNLVLKRVPSPVLIRKFSDTSKAFMDIMSAQASSGSTSALRWVSVWVSVSPLLSSRAHPTWLKLGGSPGGVLSCLATLLRKQDLEAWGYPVTLQVYQGLLSFTVHIKPKVRKAAQHGVCSVLKGSEIMFGEKAPAHHPAAIPTAKFCIQEIEKSGGSKEATTLLHMLTLLKDLLPCFPEGLVKSCSETLLRVMTLNHVLVSACAMQAFHSLFHAKPSPGTLPAELNAQIIKALYDYVPSENDLQPLLAWLKVMEKAHINLVRLHQNLGLGHLPRFFGTAMTCLLSPHSQVVTVAAQCLQEILRECVAPHMADIGSVTSSASGPAQYIAKMFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAALDHAVGAAVATMGPQVVLEAVPLEIDGSEETLDFPRSWLLPVIRDHVRETRLGFFTTYFLPLATTLKNKALDLAQAGSTVESKIYDTLQWQIWTLLPGFCTKPTDVATSFKGLARTLGTAISERPDLRVTVCQALRTLITKGCEAEADRAEVSRFAKNFLPILFNLYGQPVAAGDTPAPRRAVLETIKTYLTITEAQLVNGFLEKASEKVLDPASSDFTRLSVLDLVVALAPHADEAAISKLYSTIRPYLESKSHGIQKKAYRVLEEVCASPQGPGARFVQNHLDELKKTLLDSLRSTSSPAKRPRLKCLIHIVKKLSAEHEEFISALVPEVILCTKEVSVGARKNAFVLLVEMGHAFLRFGPSQEEALQRYLVLIYPGLVGAVTMVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVVVMDVVHLAKHVQLVMGAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKKLLPEEYHKVLVNIRKAEARAKKHRALNQAAVEEEEEEEEPVQGKGDSIEEILADSEDEDDEEERARSKEQRRLARQRSQAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGQKKDHGFKVSADGRLIIREEEDDDTAKAEEEEGAKGEDEEMADLMEDMGVRRKKHQKLKQQEADDEELEMPPQYQGEAAMLLSWSTGSCHLQ", "length": 1256, "header": "tr|A0A5G2QWF3-1|A0A5G2QWF3_PIG Isoform 1 of Ribosomal RNA processing 12 homolog OS=Sus scrofa OX=9823 GN=RRP12 PE=3 SV=1 CANONICAL=A0A5G2QWF3-1" }, "locus": { "chromosome": "14", "start_pos": 108805406, "end_pos": 108775334, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083623.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083623.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062514.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062514.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 736, "start_aa": "Thr", "end_pos": 736, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr736", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWF3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1256, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWF3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWF3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3" }, { "id": "PF08161", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08161" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRP12 HEAT", "eco_id": "ECO_0000259", "start_pos": 456, "end_pos": 729, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QWF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWF3" }, { "id": "PF25772", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25772" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRP12 N-terminal HEAT", "eco_id": "ECO_0000259", "start_pos": 111, "end_pos": 232, "start_aa": "Val", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 736 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWJ0-1", "uniprot_ac": "A0A5G2QWJ0", "uniprot_id": "A0A5G2QWJ0_PIG", "mass": { "chemical_mass": 60643.0, "monoisotopic_mass": 60643.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100736962", "type": "recommended", "evidence": [ { "id": "A0A5G2QWJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0" } ] } ], "protein_names": [ { "name": "Carboxylic ester hydrolase", "type": "recommended", "evidence": [ { "id": "A0A5G2QWJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.-", "type": "synonym", "evidence": [ { "id": "A0A5G2QWJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWJ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100736962", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0", "locus": {} } ], "crossref": [ { "id": "A0A5G2QWJ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000039985", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000039985", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00312", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00312", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2022377", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-211945", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-211945", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5578768", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5578768", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9749641", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9749641", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QWJ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RF14", "url": "https://www.uniprot.org/uniprotkb/F1RF14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RF14-1", "url": "https://www.uniprot.org/uniprotkb/F1RF14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTFHSPFLFLLPLGTLFLPRQALPFAGQPASPPVVDTAQGRVLGKYVSLEGLAQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCCQDPVVEQMTSDLFTNGKERLTLEFSEDCLYLNIYTPADLTKRGRLPVMVWIHGGGLVLGGAPMYDGVVLAAHENVVVVAIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQENIANFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTVALVRKDMKAAAKQIAVLAGCKTTTSAVFVHCLRQKSEDELLDLTLKMKFLTLDFHGDQRESHPFLPTVVDGVLLPKMPEEILAEKDFNTVPYIVGINKQEFGWLLPTMMGFPLSEGKLDQKTATSLLWKSYPIANIPEELTPVATDKYLGGTDDPVKKKDLFLDLMGDVVFGVPSVTVARQHRGESQTLDRRGTRIGSEVLSGTKKAELSEQDCVAPMVWRMLVSAAGLLPSQCELGLPAPSNLTQGCGGGGSGADESPGEEVSLWGALLRSSQDPSFSRSPPSPGLQARKRISAPELSL", "length": 562, "header": "tr|A0A5G2QWJ0-1|A0A5G2QWJ0_PIG Isoform 1 of Carboxylic ester hydrolase OS=Sus scrofa OX=9823 GN=LOC100736962 PE=3 SV=1 CANONICAL=A0A5G2QWJ0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0/entry#A0A5G2QWJ0-1", "sequence": { "sequence": "MTFHSPFLFLLPLGTLFLPRQALPFAGQPASPPVVDTAQGRVLGKYVSLEGLAQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCCQDPVVEQMTSDLFTNGKERLTLEFSEDCLYLNIYTPADLTKRGRLPVMVWIHGGGLVLGGAPMYDGVVLAAHENVVVVAIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQENIANFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTVALVRKDMKAAAKQIAVLAGCKTTTSAVFVHCLRQKSEDELLDLTLKMKFLTLDFHGDQRESHPFLPTVVDGVLLPKMPEEILAEKDFNTVPYIVGINKQEFGWLLPTMMGFPLSEGKLDQKTATSLLWKSYPIANIPEELTPVATDKYLGGTDDPVKKKDLFLDLMGDVVFGVPSVTVARQHRGESQTLDRRGTRIGSEVLSGTKKAELSEQDCVAPMVWRMLVSAAGLLPSQCELGLPAPSNLTQGCGGGGSGADESPGEEVSLWGALLRSSQDPSFSRSPPSPGLQARKRISAPELSL", "length": 562, "header": "tr|A0A5G2QWJ0-1|A0A5G2QWJ0_PIG Isoform 1 of Carboxylic ester hydrolase OS=Sus scrofa OX=9823 GN=LOC100736962 PE=3 SV=1 CANONICAL=A0A5G2QWJ0-1" }, "locus": { "chromosome": "AEMK02000576.1", "start_pos": 116819, "end_pos": 90900, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072964.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072964.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068515.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068515.1" } ] } }, { "isoform_ac": "F1RF14-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0/entry#F1RF14-1", "sequence": { "sequence": "MTFHSPFLFLLPLGTLFLPRQALPFAGQPASPPVVDTAQGRVLGKYVSLEGLAQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCCQDPVVEQMTSDLFTNGKERLTLEFSEDCLYLNIYTPADLTKRGRLPVMVWIHGGGLVLGGAPMYDGVVLAAHENVVVVAIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQENIANFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTVALVRKDMKAAAKQIAVLAGCKTTTSAVFVHCLRQKSEDELLDLTLKMKFLTLDFHGDQRESHPFLPTVVDGVLLPKMPEEILAEKDFNTVPYIVGINKQEFGWLLPTMMGFPLSEGKLDQKTATSLLWKSYPIANIPEELTPVATDKYLGGTDDPVKKKDLFLDLMGDVVFGVPSVTVARQHRGESQTLDRRGTRPYTGSFVLEGVRGQG", "length": 472, "header": "tr|F1RF14-1|A0A5G2QWJ0_PIG Computationally mapped isoform of Carboxylic ester hydrolase OS=Sus scrofa OX=9823 GN=LOC100736962 PE=3 SV=5 CANONICAL=A0A5G2QWJ0-1" }, "locus": { "chromosome": "AEMK02000576.1", "start_pos": 116451, "end_pos": 90900, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003127.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003127.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003046.5", "url": "https://www.ensembl.org/id/ENSSSCP00000003046.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RF14", "url": "https://www.uniprot.org/uniprotkb/F1RF14" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2022377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022377", "resource": "Reactome", "description": "Metabolism of Angiotensinogen to Angiotensins" }, { "id": "R-SSC-211945", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-211945", "resource": "Reactome", "description": "Phase I - Functionalization of compounds" }, { "id": "R-SSC-5578768", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5578768", "resource": "Reactome", "description": "Physiological factors" }, { "id": "R-SSC-9749641", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9749641", "resource": "Reactome", "description": "Aspirin ADME" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWJ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWJ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "short-chain fatty acid catabolic process", "id": "GO:0019626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019626", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWJ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carboxylesterase activity", "id": "GO:0106435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106435", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWJ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWJ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-5693691", "name": "CES1 trimer.CES2 hydrolyse COCN to BEG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-5693702" ], "output_participant_list": [ "R-ALL-5693711", "R-ALL-5693712" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5693691", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693691" } ] }, { "id": "R-SSC-9619024", "name": "CES1 trimer hydrolyses ACEI pro-drugs to ACEIs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [ "R-ALL-140972" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9619024", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9619024" } ] }, { "id": "R-SSC-9727567", "name": "CES1 hydrolyses sacubitril to sacubitrilat", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, lipid droplet", "input_participant_list": [ "R-ALL-9727597" ], "output_participant_list": [ "R-ALL-9727588" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9727567", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9727567" } ] }, { "id": "R-SSC-9749792", "name": "CES1,CES2 hydrolyze ASA- to ST", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-9749795" ], "output_participant_list": [ "R-ALL-9749588" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9749792", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9749792" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-140972", "participant_name": "Alcohol [endoplasmic reticulum lumen]", "crossref": [ { "id": "30879", "database": "ChEBI", "url": "" }, { "id": "C00069", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-5693702", "participant_name": "COCN [endoplasmic reticulum lumen]", "crossref": [ { "id": "27958", "database": "ChEBI", "url": "" }, { "id": "C01416", "database": "COMPOUND", "url": "" }, { "id": "2286", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000003875336", "database": "ZINC", "url": "" }, { "id": "HMDB0015043", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-5693711", "participant_name": "MeOH [endoplasmic reticulum lumen]", "crossref": [ { "id": "HMDB0001875", "database": "HMDB Metabolite", "url": "" }, { "id": "17790", "database": "ChEBI", "url": "" }, { "id": "C00132", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-5693712", "participant_name": "BEG [endoplasmic reticulum lumen]", "crossref": [ { "id": "C10847", "database": "COMPOUND", "url": "" }, { "id": "HMDB0041836", "database": "HMDB Metabolite", "url": "" }, { "id": "41001", "database": "ChEBI", "url": "" }, { "id": "ZINC000002572652", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9727588", "participant_name": "sacubitrilat [cytosol]", "crossref": [ { "id": "0005009", "database": "Mondo", "url": "" }, { "id": "7858", "database": "Guide to Pharmacology - Ligands", "url": "" } ] }, { "participant_id": "R-ALL-9727597", "participant_name": "sacubitril [cytosol]", "crossref": [ { "id": "7857", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "134714", "database": "ChEBI", "url": "" }, { "id": "0005009", "database": "Mondo", "url": "" } ] }, { "participant_id": "R-ALL-9749588", "participant_name": "acetate [endoplasmic reticulum lumen]", "crossref": [ { "id": "30089", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9749795", "participant_name": "ASA- (hepatocyte) [endoplasmic reticulum lumen]", "crossref": [ { "id": "13719", "database": "ChEBI", "url": "" }, { "id": "ZINC000000000053", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWJ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 562, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWJ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWJ0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWJ0" }, { "id": "PF00135", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carboxylesterase type B", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 448, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 505, "end_pos": 507 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWK8-1", "uniprot_ac": "A0A5G2QWK8", "uniprot_id": "A0A5G2QWK8_PIG", "mass": { "chemical_mass": 35670.0, "monoisotopic_mass": 35670.0 }, "refseq": {}, "gene_names": [ { "name": "OR6N2", "type": "recommended", "evidence": [ { "id": "A0A5G2QWK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QWK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OR6N2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8", "locus": { "chromosome": "4", "start_pos": 91491554, "end_pos": 91485019, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006423", "url": "https://www.ensembl.org/id/ENSSSCG00000006423" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006423", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006423", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15914", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15914", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157689", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157689", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGYNEIQ", "url": "https://omabrowser.org/oma/group/CGYNEIQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QWK8", "url": "https://www.orthodb.org/?gene=A0A5G2QWK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QWK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPYNLSSLAEFVLLGFPKVGHVRGWLFVLLLLAYLFTICGNMLIFLVIRLDAALHTPMYHFVSILSFLELWYTATTIPKMLANLLSDKKTISFSGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPLHYPAIMTSALCAKMAAGCWTCGFLCPISEVILISQLPFCGYNEIQHIFCDFPPLLSLACKDTSINVLVDFAINAFIILITFLFIMVSYGRIIGAVLKIKTTAGRKKAFSTCASHLSVVLIFFGSIIFMYVRLKKSYSLTLDQTLAVVYSVLTPLINPIIYSLRNKELIKAIRRTIFQKGERASPTHH", "length": 317, "header": "tr|A0A5G2QWK8-1|A0A5G2QWK8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR6N2 PE=3 SV=1 CANONICAL=A0A5G2QWK8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8/entry#A0A5G2QWK8-1", "sequence": { "sequence": "MEPYNLSSLAEFVLLGFPKVGHVRGWLFVLLLLAYLFTICGNMLIFLVIRLDAALHTPMYHFVSILSFLELWYTATTIPKMLANLLSDKKTISFSGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPLHYPAIMTSALCAKMAAGCWTCGFLCPISEVILISQLPFCGYNEIQHIFCDFPPLLSLACKDTSINVLVDFAINAFIILITFLFIMVSYGRIIGAVLKIKTTAGRKKAFSTCASHLSVVLIFFGSIIFMYVRLKKSYSLTLDQTLAVVYSVLTPLINPIIYSLRNKELIKAIRRTIFQKGERASPTHH", "length": 317, "header": "tr|A0A5G2QWK8-1|A0A5G2QWK8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR6N2 PE=3 SV=1 CANONICAL=A0A5G2QWK8-1" }, "locus": { "chromosome": "4", "start_pos": 91489449, "end_pos": 91488499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070187.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070187.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069334.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069334.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157689", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157689", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q5F1-1", "protein_name": "Olfactory receptor", "gene_name": "Or6n2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQHNFSSLTEFVLLGFPNVEHIRSCLFVLLLLVYLFTIGGNMLIFLVIRLDAALHKPMYHFVSVLSFLELWYTATTIPKMLANLLSEKKTISFAGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPLHYPSIMTTALCVKMAAGCWTCGFLCPISEVILVSQLPFCNYNEIPHIFCDFPPLLSLACKDTSTNVLVDFAVNAFIILITFLFIMASYGRIIGAVLKIKTAAGRRKAFSTCASHLIVVLIFFGSIIFMYVRLKKSYSLTLDRTLAVVYSVLTPLANPIIYSLRNKELIQAIKRTFFKKVEKASPTHH", "length": 317 }, "evidence": [ { "id": "A0A5G2QWK8", "url": "https://omabrowser.org/oma/group/A0A5G2QWK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3H814-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100751255", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDQHNFSSLSEFVLLGFPNVGHIRGCLFVLLLLAYLFTIGGNMLIFLVIRLDSALHKPMYHFVSVLSFLELWYTATTIPKMLANLLSEKKTISFAGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPLHYPSIMTTSLCAKMAAGCWTCGFLCPISEVILVSQLPFCNYNEIPHIFCDFPPLLSLACKDTSTNVLVDFAVNAFIILITFLFIMTSYGRIIGAVLKIKTAAGRRKAFSTCASHLIVVLIFFGSIIFMYVRLKKSYSLTLDRTLAVVYSVLTPLANPIIYSLRNKELIQAIKRTIFKKGEKASPTHH", "length": 317 }, "evidence": [ { "id": "A0A5G2QWK8", "url": "https://omabrowser.org/oma/group/A0A5G2QWK8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3N1W8-1", "protein_name": "Olfactory receptor", "gene_name": "OR6N2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPHNHSSLAEFVLLGFPRVGHIRGWLFVLLLLAYLFTICGNMLIFLVIRLDAALHTPMYNFVSILSFLELWYTATTIPKMLANLLSDKKTISFSGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPLHYPAVMTPMLCVKMAAGCWTCGFLCPISEVILVSQLPFCSYNEIQHIFCDFPPLLSLACKDTSTNVLVDFAINAFIILITFLFIMVSYGRIMGTILQIKTIAGRKKAFSTCASHLIVVLIFFGSIIFMYVRLKESYSLTLDRTLAVVYSVLTPLVNPIIYSLRNKELIKAIKRTIFRKGERASPTQH", "length": 317 }, "evidence": [ { "id": "A0A5G2QWK8", "url": "https://omabrowser.org/oma/group/A0A5G2QWK8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8NGY6-1", "protein_name": "Olfactory receptor 6N2", "gene_name": "OR6N2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQYNHSSLAEFVFLGFASVGYVRGWLFVLLLLAYLFTICGNMLIFSVIRLDAALHTPMYHFVSVLSFLELWYTATTIPKMLSNILSEKKTISFAGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPLHYPIIMTTTLCAKMAAACWTCGFLCPISEVILASQLPFCAYNEIQHIFCDFPPLLSLACKDTSANILVDFAINAFIILITFFFIMISYARIIGAVLKIKTASGRKKAFSTCASHLAVVLIFFGSIIFMYVRLKKSYSLTLDRTLAIVYSVLTPMVNPIIYSLRNKEIIKAIKRTIFQKGDKASLAHL", "length": 317 }, "evidence": [ { "id": "A0A5G2QWK8", "url": "https://omabrowser.org/oma/group/A0A5G2QWK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWK8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWP2-1", "uniprot_ac": "A0A5G2QWP2", "uniprot_id": "A0A5G2QWP2_PIG", "mass": { "chemical_mass": 34935.0, "monoisotopic_mass": 34935.0 }, "refseq": { "ac": "XP_013842717", "name": "olfactory receptor 4C46-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842717" }, "gene_names": [ { "name": "LOC100520951", "type": "recommended", "evidence": [ { "id": "A0A5G2QWP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2" } ] }, { "name": "LOC100520951", "type": "synonym", "evidence": [ { "id": "XP_013842717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842717" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QWP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4C46-like", "type": "synonym", "evidence": [ { "id": "XP_013842717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842717" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100520951", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2", "locus": {} } ], "crossref": [ { "id": "A0A5G2QWP2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045754", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045754", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100520951", "url": "https://www.ncbi.nlm.nih.gov/gene/100520951", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520951", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520951", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QWP2", "url": "https://www.orthodb.org/?gene=A0A5G2QWP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013842717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842717", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QWP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNHRETRNNVTEFILLGLTQNSHMQKVIFVVFLLIYAVSLGGNVLTIVTITTSPLIGCPMYYFLAHLSFIDACCSCVDTPKLVVDSLYEKKTSTFHGCMMQIFGEHFFGGADIILLTAMAYDRYVAICKPLYYATIMNRQLCGLLVGVSWLGGFLHGFIQILFIFRLPFCGPNVIDHFMCDLIPLLKLACTDTHTLGLFVAANSGFICLLNFLLLLGSYGVILHTLRTQSLEARRKALSTCVSHITAVVIFFVPCIFVYMRPAVTLPFDKAVAVFYSMITPMLNPLIYTLRNAQLKNAVRKLFHRNAISGEI", "length": 312, "header": "tr|A0A5G2QWP2-1|A0A5G2QWP2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100520951 PE=3 SV=2 CANONICAL=A0A5G2QWP2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2/entry#A0A5G2QWP2-1", "sequence": { "sequence": "MNHRETRNNVTEFILLGLTQNSHMQKVIFVVFLLIYAVSLGGNVLTIVTITTSPLIGCPMYYFLAHLSFIDACCSCVDTPKLVVDSLYEKKTSTFHGCMMQIFGEHFFGGADIILLTAMAYDRYVAICKPLYYATIMNRQLCGLLVGVSWLGGFLHGFIQILFIFRLPFCGPNVIDHFMCDLIPLLKLACTDTHTLGLFVAANSGFICLLNFLLLLGSYGVILHTLRTQSLEARRKALSTCVSHITAVVIFFVPCIFVYMRPAVTLPFDKAVAVFYSMITPMLNPLIYTLRNAQLKNAVRKLFHRNAISGEI", "length": 312, "header": "tr|A0A5G2QWP2-1|A0A5G2QWP2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100520951 PE=3 SV=2 CANONICAL=A0A5G2QWP2-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 153873, "end_pos": 152938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082206.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082206.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062599.2", "url": "https://www.ensembl.org/id/ENSSSCP00000062599.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520951", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520951", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWP2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWP2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWP2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWP2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWU6-1", "uniprot_ac": "A0A5G2QWU6", "uniprot_id": "A0A5G2QWU6_PIG", "mass": { "chemical_mass": 34614.0, "monoisotopic_mass": 34614.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "L1 transposable element RRM domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWU6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6", "locus": {} } ], "crossref": [ { "id": "A0A5G2QWU6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWU6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QWU6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSLTELEFKREILKILKELREDMNSNADTLQKELENIRMSQEKLEHSFAEIQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKQESNIRDLWDNIKWANLRIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRSSADFSTETLQARRERQEIFKVLKGKNMQPRILYPARISFKIEGEIKFFSNKQKLKEYSHTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2QWU6-1|A0A5G2QWU6_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QWU6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6/entry#A0A5G2QWU6-1", "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSLTELEFKREILKILKELREDMNSNADTLQKELENIRMSQEKLEHSFAEIQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKQESNIRDLWDNIKWANLRIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRSSADFSTETLQARRERQEIFKVLKGKNMQPRILYPARISFKIEGEIKFFSNKQKLKEYSHTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2QWU6-1|A0A5G2QWU6_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QWU6-1" }, "locus": { "chromosome": "X", "start_pos": 99542584, "end_pos": 99541697, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083317.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083317.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069341.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069341.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWU6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWU6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWU6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWU6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWU6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 296, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWU6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWU6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 227, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6" }, { "id": "PF17490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element dsRBD-like", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 293, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWU6" }, { "id": "PF17489", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element trimerization", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 128, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3H9-1", "uniprot_ac": "A0A5G2R3H9", "uniprot_id": "A0A5G2R3H9_PIG", "mass": { "chemical_mass": 71976.0, "monoisotopic_mass": 71976.0 }, "refseq": { "ac": "XP_020949260", "name": "interleukin-23 receptor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949260" }, "gene_names": [ { "name": "IL23R", "type": "recommended", "evidence": [ { "id": "A0A5G2R3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ] }, { "name": "IL23RA", "type": "synonym", "evidence": [ { "id": "XP_020949260", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949260" } ] }, { "name": "IL23R", "type": "synonym", "evidence": [ { "id": "XP_020949260", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949260" } ] } ], "protein_names": [ { "name": "Interleukin-23 receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9/entry#names_and_taxonomy" } ] }, { "name": "interleukin-23 receptor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020949260", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949260" } ] } ], "function": [ { "annotation": "Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9#function" }, { "database": "UniProtKB", "id": "ARBA00058776", "url": "https://www.uniprot.org/uniprotkb/ARBA00058776#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IL23R", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9", "locus": { "chromosome": "6", "start_pos": 145335741, "end_pos": 145401510, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003801", "url": "https://www.ensembl.org/id/ENSSSCG00000003801" } ] } } ], "crossref": [ { "id": "A0A5G2R3H9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3H9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003801", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003801", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "733613", "url": "https://www.ncbi.nlm.nih.gov/gene/733613", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NWCHGGI", "url": "https://omabrowser.org/oma/group/NWCHGGI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R3H9", "url": "https://www.orthodb.org/?gene=A0A5G2R3H9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48423", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48423", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48423:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48423:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-SSC-9020933", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9020933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020949260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949260", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QWW4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQVTTQWDVVIALYIFFNWCHGGITNINCSGHIWVEPAAVFKMGVNISIYCQATIKNCQPRKIYFYKNGIKERFQITRINKTISRLWYNNFLEPQAFVYCTAECPGYFQETLICGKDISSGYPPDVPDKVTCVIYEYSGNMTCTWDAGKPTYIATKYVVYVKSLETEEEQEYLTSSYINISTDSLQGSKKYLVWVQATNVLGMEKSKQLQVHLDDIVIPSASIISRAEDINTTVPRTVIHWSSQTSIERVSCEMRYKATTNQTWKVKEFDVNLTYMQQSEFYLQPNTKYIFQVRCQETGKRYWQPWSSPFFHKTPETVPQVTVKSFQHDAQNSGLPVASIFKGHLTSDNRQQDIGLLLGMVFFAVLLSILSLIGIFNRSLRTGIKRRLLLLIPKWLYEDIPNMENSHVVKMLQEKSEFMNNNSSKQVLYVDPVITEIEIFLPEEKPMGYKKEKNTGSLETRNSLQTSLLSNTTVVYIPDLNTGYKPQISNFLTGGNHLSNNDETASSTLEPPADALNLGKNARFKKHPHFAFSVSSMTSLSNTLFLEELSLILNQGECSPTDLQNSIEGETTVQLLENASPNETIPEQTLLPDEFVSCLGRMNTELPSINSYFPQNILESHFNRISLLEK", "length": 631, "header": "tr|A0A5G2R3H9-1|A0A5G2R3H9_PIG Isoform 1 of Interleukin-23 receptor OS=Sus scrofa OX=9823 GN=IL23R PE=3 SV=1 CANONICAL=A0A5G2R3H9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9/entry#A0A5G2QWW4-1", "sequence": { "sequence": "MPRLKPGTNKVKEFDVNLTYMQQSEFYLQPNTKYIFQVRCQETGKRYWQPWSSPFFHKTPETVPQVTVKSFQHDAQNSGLPVASIFKGHLTSDNRQQDIGLLLGMVFFAVLLSILSLIGIFNRSLRTGIKRRLLLLIPKWLYEDIPNMENSHVVKMLQEKSEFMNNNSSKQVLYVDPVITEIEIFLPEEKPMGYKKEKNTGSLETRNSLQTSLLSNTTVVYIPDLNTGYKPQISNFLTGGNHLSNNDETASSTLEPPADALNLGKNARFKKHPHFAFSVSSMTSLSNTLFLEELSLILNQGECSPTDLQNSIEGETTVQLLENASPNETIPEQTLLPDEFVSCLGRMNTELPSINSYFPQNILESHFNRISLLEK", "length": 375, "header": "tr|A0A5G2QWW4-1|A0A5G2R3H9_PIG Computationally mapped isoform of Interleukin-23 receptor OS=Sus scrofa OX=9823 GN=IL23R PE=3 SV=2 CANONICAL=A0A5G2R3H9-1" }, "locus": { "chromosome": "6", "start_pos": 145370145, "end_pos": 145338374, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083963.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083963.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066429.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066429.2" } ] } }, { "isoform_ac": "A0A5G2R3H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9/entry#A0A5G2R3H9-1", "sequence": { "sequence": "MNQVTTQWDVVIALYIFFNWCHGGITNINCSGHIWVEPAAVFKMGVNISIYCQATIKNCQPRKIYFYKNGIKERFQITRINKTISRLWYNNFLEPQAFVYCTAECPGYFQETLICGKDISSGYPPDVPDKVTCVIYEYSGNMTCTWDAGKPTYIATKYVVYVKSLETEEEQEYLTSSYINISTDSLQGSKKYLVWVQATNVLGMEKSKQLQVHLDDIVIPSASIISRAEDINTTVPRTVIHWSSQTSIERVSCEMRYKATTNQTWKVKEFDVNLTYMQQSEFYLQPNTKYIFQVRCQETGKRYWQPWSSPFFHKTPETVPQVTVKSFQHDAQNSGLPVASIFKGHLTSDNRQQDIGLLLGMVFFAVLLSILSLIGIFNRSLRTGIKRRLLLLIPKWLYEDIPNMENSHVVKMLQEKSEFMNNNSSKQVLYVDPVITEIEIFLPEEKPMGYKKEKNTGSLETRNSLQTSLLSNTTVVYIPDLNTGYKPQISNFLTGGNHLSNNDETASSTLEPPADALNLGKNARFKKHPHFAFSVSSMTSLSNTLFLEELSLILNQGECSPTDLQNSIEGETTVQLLENASPNETIPEQTLLPDEFVSCLGRMNTELPSINSYFPQNILESHFNRISLLEK", "length": 631, "header": "tr|A0A5G2R3H9-1|A0A5G2R3H9_PIG Isoform 1 of Interleukin-23 receptor OS=Sus scrofa OX=9823 GN=IL23R PE=3 SV=1 CANONICAL=A0A5G2R3H9-1" }, "locus": { "chromosome": "6", "start_pos": 145400297, "end_pos": 145338374, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085477.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085477.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071641.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071641.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWW4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9020933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9020933", "resource": "Reactome", "description": "Interleukin-23 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LX96-1", "protein_name": "Interleukin-23 receptor", "gene_name": "Il23r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRREREMRGFYYIWDMSHVALQLHVVIALYALFRWGHGGIATINCSGNMWVEPGEIFQMGMNVSVYCQEALKNCRPRNLHFYKNGFKERFHITRINRTTARVWYKGFSEPHASMYCTAECPGRFQETLICGKDISSGYPPDAPSNMTCVIYEYSGNMTCTWNTGKPTYIDTKYTVHVKSLETEEQQQYLASNYVNISTDSLQGGRKYLVWVQAVNALGMENSQQLQVHLDDIVIPSPSIISRAETTNANVPKTIIYWKSKIMTGKVFCEMRYKATTNQTWNVKEFDTNYTYVQQSEFYLEPNSKYVFQVRCQGTGKRNWQPWSSPFVHQTPQTASQVTSKPPHEPQKIEMLTATIFKGHSTSDNSQDIGLLSGMVFLAILLPIFSLIGIFNRSLRIGIKRKVLLMIPKWLYEDIPNMENSNIAKLLQEKSVFENENASEQALYVDPILTEISEISPLEHKPTDYKKDRLTGFLETRDCPLTTLSTSSSVVYIPDLNTGYKPQVSNVPPEENHFINRDERDPMSLEATGDHFARLKTYPNFTFSASSMTSLSKTLILDELSLVLNQGEFNSLDIQNSRQEETSMILQNDSPSETIPVQTLLPDEFVSCLAIGSEDLPSINSYFPQNVLESHFSGIPLLQK", "length": 639 }, "evidence": [ { "id": "A0A5G2R3H9", "url": "https://omabrowser.org/oma/group/A0A5G2R3H9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MZJ0-1", "protein_name": "Interleukin-23 receptor", "gene_name": "IL23R", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNQVTIHWDVVIALYIFFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQPSKLYFYKNGIKERFHITRINKTTARLWYNNFVEPQAFVYCTAECSRYFPETLICGKDISSGYPPDVPDKVACVIYEYSGNMTCTWNPGRPTYIDTKYVVYVKSLETEEEQEYLTSSYINISTDSLQKGKKYLVWVQASNVLGMEKSKQLQIHLDDIVIPSASIISRAEDINTTVSKTVIHWDSQTSIEKVSCEMRYKDTTNQTWNVKEFDTNFTYEQQSEFYLQPNAMYVFQVRCQETGKKYWQPWSSPFFHKTPEIVPQVTMKSFQHDTQNSGLLIASIFKKHLTSDNRKQDIGLLLGMVFFAVMLSVLSLIGIFNRSLRTGIKRRILLLIPKWLYEDIPNMENSKVVKILQERNEFMNNNSSEQVLYVDPVITEIEIILPEEKPMGYKKENNTGCLERKESLEKSLLTDTTVVYIPDLNTGYKPQISSFLPGGNHLSNDDETASSILEPPADSLNLGNNARFKKYPDFAFSVSSTNSLSNTLFLEELNLILNQGECSPPDMQNSIEGETAMLLEDALLNETIPEQTLLPDEFVSCLGSMNKELPSINSYFPQNILESHFNRISLLEK", "length": 630 }, "evidence": [ { "id": "A0A5G2R3H9", "url": "https://omabrowser.org/oma/group/A0A5G2R3H9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5VWK5-1", "protein_name": "Interleukin-23 receptor", "gene_name": "IL23R", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQPRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYINISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMNNNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDLNTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSLSNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGIVNEELPSINTYFPQNILESHFNRISLLEK", "length": 629 }, "evidence": [ { "id": "A0A5G2R3H9", "url": "https://omabrowser.org/oma/group/A0A5G2R3H9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K4B4-1", "protein_name": "Interleukin-23 receptor", "gene_name": "Il23r", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHLTLQLHVVIALYVLFRWCHGGITSINCSGDMWVEPGEIFQMGMNVSIYCQEALKHCRPRNLYFYKNGFKEEFDITRINRTTARIWYKGFSEPHAYMHCTAECPGHFQETLICGKDISSGHPPDAPSNLTCVIYEYSGNMTCTWNTGKPTYIDTKYIVHVKSLETEEEQQYLASSYVKISTDSLQGSRKYLVWVQAVNSLGMENSQQLHVHLDDIVIPSASIISRAETTNDTVPKTIVYWKSKTMIEKVFCEMRYKTTTNQTWSVKEFDANFTYVQQSEFYLEPDSKYVFQVRCQETGKRNWQPWSSPFVHQTSQETGKRNWQPWSSPFVHQTSQTVSQVTAKSSHEPQKMEMLSATIFRGHPASGNHQDIGLLSGMVFLAIMLPIFSLIGIFNRSLRIGIKRKVLLMIPKWLYEDIPNMENSNVAKLLQEKSVFENDNASEQALYVDPVLTEISEISPLEHKPTDYKEERLTGLLETRDCPLGMLSTSSSVVYIPDLNTGYKPQVSNVPPGGNLFINRDERDPTSLETTDDHFARLKTYPNFQFSASSMALLNKTLILDELCLVLNQGEFNSLDIKNSRQEETSIVLQSDSPSETIPAQTLLSDEFVSCLAIGNEDLPSINSYFPQNVLESHFSRISLFQK", "length": 644 }, "evidence": [ { "id": "A0A5G2R3H9", "url": "https://omabrowser.org/oma/group/A0A5G2R3H9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "interleukin-23 receptor complex", "id": "GO:0072536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072536", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "negative regulation of interleukin-10 production", "id": "GO:0032693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032693", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "positive regulation of defense response to virus by host", "id": "GO:0002230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "positive regulation of type II interferon production", "id": "GO:0032729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "response to type II interferon", "id": "GO:0034341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034341", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "positive regulation of interleukin-12 production", "id": "GO:0032735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032735", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "positive regulation of T-helper 1 type immune response", "id": "GO:0002827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002827", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "interleukin-12 receptor binding", "id": "GO:0005143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005143", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "prolactin receptor activity", "id": "GO:0004925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004925", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "interleukin-23 binding", "id": "GO:0042019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042019", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" }, { "name": "interleukin-23 receptor activity", "id": "GO:0042020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 579, "end_pos": 581, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R3H9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 631, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R3H9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3H9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H9" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 222, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 180, "end_pos": 182 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 262, "end_pos": 264 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 378, "end_pos": 380 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 472, "end_pos": 474 }, { "start_pos": 47, "end_pos": 49 }, { "start_pos": 579, "end_pos": 581 }, { "start_pos": 583, "end_pos": 585 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWW7-1", "uniprot_ac": "A0A5G2QWW7", "uniprot_id": "A0A5G2QWW7_PIG", "mass": { "chemical_mass": 75313.0, "monoisotopic_mass": 75313.0 }, "refseq": {}, "gene_names": [ { "name": "KIRREL2", "type": "recommended", "evidence": [ { "id": "A0A5G2QWW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7" } ] } ], "protein_names": [ { "name": "Kin of IRRE-like protein 2", "type": "recommended", "evidence": [ { "id": "A0A5G2QWW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7/entry#names_and_taxonomy" } ] }, { "name": "Kin of irregular chiasm-like protein 2", "type": "synonym", "evidence": [ { "id": "A0A5G2QWW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May regulate basal insulin secretion.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDR2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDR2#function" }, { "database": "UniProtKB", "id": "ARBA00053990", "url": "https://www.uniprot.org/uniprotkb/ARBA00053990#function" }, { "database": "UniProtKB", "id": "A0A5G2QWW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7#function" }, { "database": "UniProtKB", "id": "F1RLG9", "url": "https://www.uniprot.org/uniprotkb/F1RLG9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KIRREL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7", "locus": { "chromosome": "6", "start_pos": 45284444, "end_pos": 45275716, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002915", "url": "https://www.ensembl.org/id/ENSSSCG00000002915" } ] } } ], "crossref": [ { "id": "A0A5G2QWW7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWW7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002915", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002915", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11640", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11640", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11640:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11640:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-373753", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-373753", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QWW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R115", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R115", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R115-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R115-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDR2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RLG9", "url": "https://www.uniprot.org/uniprotkb/F1RLG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RLG9-1", "url": "https://www.uniprot.org/uniprotkb/F1RLG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "TLRMLVPTLLVLFFLFLRGRAGLLPHFLQQPEDLVVLLGDEARLPCALGAYWGLVQWTKDGLALGGERDLPGWSRYWISGNAAGGQHDLHIRPVELEDQASYECQATQAGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGIPANLTCRSRGDAHPTPELLWFRDGVQLDGATFHQTLLKEGTTGSTGSVESILSLTPSSHDDGATLVCRARSQALPVGKDTAITLSLQYPPVVTLSAEPQRVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPMLEVVADASFLTEPVSCEVSNAVGSANRSTALDVQFGPILQSKPKPLSVDVGEDASFSCVWRGNPLPRVTWTRRGEAQVMASGPTLRLPAVGLEDAGDYVCRAEPGLSGLGGGAAEARLTVNAPPVVTALHSAPAFLRGPARLQCLVFASPAPEAVVWSWDEGFLTAGSRGRFLVETFPAPEGRGGQGPGLISVLHISGTQESDFSRGFNCSARNRLGEGGTLVTLGRRDLLPTVRIVAGAAAVAMTLLMVITGVALCCWHHNKASASFSKQKNLVRIQGSSDGSSSRGPEEETGSGEDQGPIMHTDHSDLVLDEERALETKDPTNGYYKVRGVSVSLSLGEAPGGGLFPPPSSPLGPPGTPAFYDFNPHLGMVPPCRLYRARAGYLTTPHPRAFTSYIKPTSFGPPDLGPSTPPFPYAAFPTPSHPRLQTHV", "length": 711, "header": "tr|A0A5G2QWW7-1|A0A5G2QWW7_PIG Isoform 1 of Kin of IRRE-like protein 2 OS=Sus scrofa OX=9823 GN=KIRREL2 PE=3 SV=1 CANONICAL=A0A5G2QWW7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7/entry#A0A5G2QWW7-1", "sequence": { "sequence": "TLRMLVPTLLVLFFLFLRGRAGLLPHFLQQPEDLVVLLGDEARLPCALGAYWGLVQWTKDGLALGGERDLPGWSRYWISGNAAGGQHDLHIRPVELEDQASYECQATQAGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGIPANLTCRSRGDAHPTPELLWFRDGVQLDGATFHQTLLKEGTTGSTGSVESILSLTPSSHDDGATLVCRARSQALPVGKDTAITLSLQYPPVVTLSAEPQRVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPMLEVVADASFLTEPVSCEVSNAVGSANRSTALDVQFGPILQSKPKPLSVDVGEDASFSCVWRGNPLPRVTWTRRGEAQVMASGPTLRLPAVGLEDAGDYVCRAEPGLSGLGGGAAEARLTVNAPPVVTALHSAPAFLRGPARLQCLVFASPAPEAVVWSWDEGFLTAGSRGRFLVETFPAPEGRGGQGPGLISVLHISGTQESDFSRGFNCSARNRLGEGGTLVTLGRRDLLPTVRIVAGAAAVAMTLLMVITGVALCCWHHNKASASFSKQKNLVRIQGSSDGSSSRGPEEETGSGEDQGPIMHTDHSDLVLDEERALETKDPTNGYYKVRGVSVSLSLGEAPGGGLFPPPSSPLGPPGTPAFYDFNPHLGMVPPCRLYRARAGYLTTPHPRAFTSYIKPTSFGPPDLGPSTPPFPYAAFPTPSHPRLQTHV", "length": 711, "header": "tr|A0A5G2QWW7-1|A0A5G2QWW7_PIG Isoform 1 of Kin of IRRE-like protein 2 OS=Sus scrofa OX=9823 GN=KIRREL2 PE=3 SV=1 CANONICAL=A0A5G2QWW7-1" }, "locus": { "chromosome": "6", "start_pos": 45283440, "end_pos": 45275943, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080790.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080790.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062680.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062680.1" } ] } }, { "isoform_ac": "A0A5G2R115-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7/entry#A0A5G2R115-1", "sequence": { "sequence": "TLRMLVPTLLVLFFLFLRGRAGWSRYWISGNAAGGQHDLHIRPVELEDQASYECQATQAGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGIPANLTCRSRGDAHPTPELLWFRDGVQLDGATFHQTLLKEGTTGSTGSVESILSLTPSSHDDGATLVCRARSQALPVGKDTAITLSLQYPPVVTLSAEPQRVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPMLEVVADASFLTEPVSCEVSNAVGSANRSTALDVQFGPILQSKPKPLSVDVGEDASFSCVWRGNPLPRVTWTRRGEAQVMASGPTLRLPAVGLEDAGDYVCRAEPGLSGLGGGAAEARLTVNAPPVVTALHSAPAFLRGPARLQCLVFASPAPEAVVWSWDEGFLTAGSRGRFLVETFPAPEGRGGQGPGLISVLHISGTQESDFSRGFNCSARNRLGEGGTLVTLGRRDLLPTVRIVAGAAAVAMTLLMVITGVALCCWHHNKASASFSKQKNLVRIQGSSDGSSSRGPEEETGSGEDQGPIMHTDHSDLVLDEERALETKDPTNGYYKVRGVSPSASPDSCVTSLQLKSPGIFNLP", "length": 586, "header": "tr|A0A5G2R115-1|A0A5G2R115_PIG Computationally mapped isoform of Kirre like nephrin family adhesion molecule 2 OS=Sus scrofa OX=9823 GN=KIRREL2 PE=3 SV=1 CANONICAL=A0A5G2QWW7-1" }, "locus": { "chromosome": "6", "start_pos": 45283484, "end_pos": 45275943, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089044.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089044.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064196.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064196.1" } ] } }, { "isoform_ac": "A0A5G2RDR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7/entry#A0A5G2RDR2-1", "sequence": { "sequence": "TLRMLVPTLLVLFFLFLRGRAGLLPHFLQQPEDLVVLLGDEARLPCALGAYWGLVQWTKDGLALGGERDLPGWSRYWISGNAAGGQHDLHIRPVELEDQASYECQATQAGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGIPANLTCRSRGDAHPTPELLWFRDGVQLDGATFHQTLLKEGTTGSTGSVESILSLTPSSHDDGATLVCRARSQALPVGKDTAITLSLQYPPVVTLSAEPQRVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPMLEVVADASFLTEPVSCEVSNAVGSANRSTALDVQFGPILQSKPKPLSVDVGEDASFSCVWRGNPLPRVTWTRRGEAQVMASGPTLRLPAVGLEDAGDYVCRAEPGLSGLGGGAAEARLTVNAPPVVTALHSAPAFLRGPARLQCLVFASPAPEAVVWSWDEGFLTAGSRGRFLVETFPAPEGRGGQGPGLISVLHISGTQESDFSRGFNCSARNRLGEGGTLVTLGRRASASFSKQKNLVRIQGSSDGSSSRGPEEETGSGEDQGPIMHTDHSDLVLDEERALETKDPTNGYYKVRGVSVSLSLGEAPGGGLFPPPSSPLGPPGTPAFYDFNPHLGMVPPCRLYRARAGYLTTPHPRAFTSYIKPTSFGPPDLGPSTPPFPYAAFPTPSHPRLQTHV", "length": 676, "header": "tr|A0A5G2RDR2-1|A0A5G2QWW7_PIG Computationally mapped isoform of Kin of IRRE-like protein 2 OS=Sus scrofa OX=9823 GN=KIRREL2 PE=3 SV=1 CANONICAL=A0A5G2QWW7-1" }, "locus": { "chromosome": "6", "start_pos": 45283440, "end_pos": 45275943, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083270.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083270.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068905.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068905.1" } ] } }, { "isoform_ac": "F1RLG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7/entry#F1RLG9-1", "sequence": { "sequence": "TLRMLVPTLLVLFFLFLRGRAGLLPHFLQQPEDLVVLLGDEARLPCALGAYWGLVQWTKDGLALGGERDLPGWSRYWISGNAAGGQHDLHIRPVELEDQASYECQATQAGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGIPANLTCRSRGDAHPTPELLWFRDGVQLDGATFHQTLLKEGTTGSTGSVESILSLTPSSHDDGATLVCRARSQALPVGKDTAITLSLQYPPVVTLSAEPQRVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPMLEVVADASFLTEPVSCEVSNAVGSANRSTALDVQFGPILQSKPKPLSVDVGEDASFSCVWRGNPLPRVTWTRRGEAQVMASGPTLRLPAVGLEDAGDYVCRAEPGLSGLGGGAAEARLTVNAPPVVTALHSAPAFLRGPARLQCLVFASPAPEAVVWSWDEGFLTAGSRGRFLVETFPAPEGRGGQGPGLISVLHISGTQESDFSRGFNCSARNRLGEGGTLVTLGRRDLLPTVRIVAGAAAVAMTLLMVITGVALCCWHHNKASASFSKQKNLVRIQGSSDGSSSRGPEEETGSGEDQGPIMHTDHSDLVLDEERALETKDPTNGYYKVRGVSPSASPDSCVTSLQLKSPGIFNLP", "length": 636, "header": "tr|F1RLG9-1|A0A5G2QWW7_PIG Computationally mapped isoform of Kin of IRRE-like protein 2 OS=Sus scrofa OX=9823 GN=KIRREL2 PE=3 SV=4 CANONICAL=A0A5G2QWW7-1" }, "locus": { "chromosome": "6", "start_pos": 45283484, "end_pos": 45275943, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003220.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003220.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003139.4", "url": "https://www.ensembl.org/id/ENSSSCP00000003139.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 639, "start_aa": "Thr", "end_pos": 639, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr639", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 701, "start_aa": "Thr", "end_pos": 701, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr701", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDR2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDR2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-373753", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-373753", "resource": "Reactome", "description": "Nephrin family interactions" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7" } ], "pmid": "" }, { "name": "slit diaphragm", "id": "GO:0036057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036057", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWW7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 711, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWW7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWW7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWW7" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 119, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 639, 701 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 488, "end_pos": 490 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWY3-1", "uniprot_ac": "A0A5G2QWY3", "uniprot_id": "A0A5G2QWY3_PIG", "mass": { "chemical_mass": 21140.0, "monoisotopic_mass": 21140.0 }, "refseq": {}, "gene_names": [ { "name": "OVOL3", "type": "recommended", "evidence": [ { "id": "A0A5G2QWY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ] } ], "protein_names": [ { "name": "Ovo like zinc finger 3", "type": "synonym", "evidence": [ { "id": "A0A5G2QWY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OVOL3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3", "locus": { "chromosome": "6", "start_pos": 45480786, "end_pos": 45478098, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000042327", "url": "https://www.ensembl.org/id/ENSSSCG00000042327" } ] } } ], "crossref": [ { "id": "A0A5G2QWY3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWY3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000042327", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042327", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10032", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10032", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10032:SF220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10032:SF220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRAFLVRSRRPQPPDWGHLPDQLRGDTYVPDLSSQGGQPAHQSSGLGDSWAAQPSQGTLTAAPRGPGTLGCPLCPKAFPLQRMLTRHLKCHSPARRHVCRCCGKGFHDAFDLKRHMRTHTGIRPFRCGACGKAFTQRCSLEAHLAKVHGQPASYAYRERREKLHVCEDCGFTSSRPEAYAQHRALHRTA", "length": 190, "header": "tr|A0A5G2QWY3-1|A0A5G2QWY3_PIG Isoform 1 of Ovo like zinc finger 3 OS=Sus scrofa OX=9823 GN=OVOL3 PE=3 SV=2 CANONICAL=A0A5G2QWY3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3/entry#A0A5G2QWY3-1", "sequence": { "sequence": "MPRAFLVRSRRPQPPDWGHLPDQLRGDTYVPDLSSQGGQPAHQSSGLGDSWAAQPSQGTLTAAPRGPGTLGCPLCPKAFPLQRMLTRHLKCHSPARRHVCRCCGKGFHDAFDLKRHMRTHTGIRPFRCGACGKAFTQRCSLEAHLAKVHGQPASYAYRERREKLHVCEDCGFTSSRPEAYAQHRALHRTA", "length": 190, "header": "tr|A0A5G2QWY3-1|A0A5G2QWY3_PIG Isoform 1 of Ovo like zinc finger 3 OS=Sus scrofa OX=9823 GN=OVOL3 PE=3 SV=2 CANONICAL=A0A5G2QWY3-1" }, "locus": { "chromosome": "6", "start_pos": 45480732, "end_pos": 45478918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066472.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066472.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069381.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069381.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "epidermal cell differentiation", "id": "GO:0009913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009913", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "pmid": "" }, { "name": "regulation of keratinocyte differentiation", "id": "GO:0045616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045616", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "pmid": "" }, { "name": "regulation of keratinocyte proliferation", "id": "GO:0010837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010837", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "pmid": "" }, { "name": "negative regulation of multicellular organismal process", "id": "GO:0051241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051241", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWY3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 190, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWY3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWY3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWY3" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 97, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWZ0-1", "uniprot_ac": "A0A5G2QWZ0", "uniprot_id": "A0A5G2QWZ0_PIG", "mass": { "chemical_mass": 34777.0, "monoisotopic_mass": 34777.0 }, "refseq": { "ac": "XP_013834967", "name": "olfactory receptor 8B3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834967" }, "gene_names": [ { "name": "LOC106504905", "type": "synonym", "evidence": [ { "id": "XP_013834967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834967" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QWZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8B3-like", "type": "synonym", "evidence": [ { "id": "XP_013834967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834967" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0", "locus": {} } ], "crossref": [ { "id": "A0A5G2QWZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044352", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044352", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15405", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15405", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "106504905", "url": "https://www.ncbi.nlm.nih.gov/gene/106504905", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:106504899", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106504899", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ssc:106504905", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106504905", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YCFFIIS", "url": "https://omabrowser.org/oma/group/YCFFIIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QWZ0", "url": "https://www.orthodb.org/?gene=A0A5G2QWZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013834967", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834967", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QWZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPGNGSFVTDFILVGLTDHPALQLPLFLLFLAMYMVTVLGNFGLITVIGLNSHLHTPMYFFLFNLSFIDLCYSSVLTPKMLTHFSSEKKIISYLGCMTQLFFFCFFVISEAYVLTAMAYDRYVAICNPLLYNITMSPKVCSSLMLACYLMALSGAMAHTGCMLRLTFCDANTINHYFCDILPLLQLSCTSTYVNEMIVFIVGGTNISVPSLTIFVSYGLILSNILHISSMESRSKAFSTCSSHIIAVSLFFGSGAIMYLRPSSSGSMDKGKISSVFYTNVVPMMNPLIYSFRNKDVKFALQKTLRRRFRF", "length": 311, "header": "tr|A0A5G2QWZ0-1|A0A5G2QWZ0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QWZ0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0/entry#A0A5G2QWZ0-1", "sequence": { "sequence": "MAPGNGSFVTDFILVGLTDHPALQLPLFLLFLAMYMVTVLGNFGLITVIGLNSHLHTPMYFFLFNLSFIDLCYSSVLTPKMLTHFSSEKKIISYLGCMTQLFFFCFFVISEAYVLTAMAYDRYVAICNPLLYNITMSPKVCSSLMLACYLMALSGAMAHTGCMLRLTFCDANTINHYFCDILPLLQLSCTSTYVNEMIVFIVGGTNISVPSLTIFVSYGLILSNILHISSMESRSKAFSTCSSHIIAVSLFFGSGAIMYLRPSSSGSMDKGKISSVFYTNVVPMMNPLIYSFRNKDVKFALQKTLRRRFRF", "length": 311, "header": "tr|A0A5G2QWZ0-1|A0A5G2QWZ0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QWZ0-1" }, "locus": { "chromosome": "9", "start_pos": 50817239, "end_pos": 50816307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091060.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091060.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066454.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066454.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:106504899", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106504899", "resource": "KEGG Pathway" }, { "id": "ssc:106504905", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106504905", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LNU4-1", "protein_name": "Olfactory receptor", "gene_name": "OR8B1AU", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPGNGSFVTEFILVGLTDQPDLQLPLFFLFLVMYMVTVLGNFGLLTLIVLNSHLHTAMYFFLFNLSLIDLCYSSVFTPKMLVDFLSKKNMISYMGCMTQLYFFCFFVISECYVLTSMAYDRYVAICNPLLYNVVMSPKVCSSLMLGSYLMAFSGAMAHTGCMLRLTFCDANTINHYLCDILPVLQLSCTSTYMNELVVFIVSGINIIVPSLTIFVSYGLILSNILHISSTEGRSKAFSTCSSHIIAVSLFFGSGAIMYLKPSSAGSMHVGKISSVFYTNVVPMMNPLTYSLRNKDVKLALKKTLGRGNF", "length": 310 }, "evidence": [ { "id": "A0A5G2QWZ0", "url": "https://omabrowser.org/oma/group/A0A5G2QWZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZU37-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASANVSLVTEFILVGLTNQPDLQIPLFFVFLIMYIVTALGNLCLIILIVLNSHLHTPMYFFLFNLSFIDLCYSTVFTPKMLMNFILSKNAISYMGCLTKLYFFCFFVISECYVLTSMAYDRFVAISNPLLYTVAMSPKLCLNLMLGTYLMAFSGAMAHTGCMLRLTFCDANTINHYFCDILPVMQLSCTSTYVNELVVFIVVGINIIVPSITIFISYGFILSSIFHIKSNEGRSKAFSTCSSHIIAVCLFFGSGAFMYLKPSSSSSMDQGKTSSVFYTNVVPMMNPLIYSLRNKDVKMALRKTLSRRKF", "length": 310 }, "evidence": [ { "id": "A0A5G2QWZ0", "url": "https://omabrowser.org/oma/group/A0A5G2QWZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWZ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWZ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWZ0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QWZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 206, "end_pos": 208 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QWZ7-1", "uniprot_ac": "A0A5G2QWZ7", "uniprot_id": "A0A5G2QWZ7_PIG", "mass": { "chemical_mass": 26587.0, "monoisotopic_mass": 26587.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Claudin", "type": "recommended", "evidence": [ { "id": "A0A5G2QWZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ7", "locus": {} } ], "crossref": [ { "id": "A0A5G2QWZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050596", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050596", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QWZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDGGPEIHGKCSLPSGPSLAPDAPSSADGSPWSASTSPLFNGRLKLQLMGFVVATVGWVLGTTSMALAEWRVWYVNSTSLLSSHLACVGVWRACIFHQGNGLDRAIGCQGYSYFDPYIPMDIHVAQILLPLATVLGLFSKAAIIFALKSMYLSKVQKTCDPSAVAGMLSIAASFCILAAVVWNQLSIQTEEGIAFPPSFNLPFKPDSQEVGGAALMAFLGSCGLFFGGLAYFSYKYPLDSRVHPTTSDT", "length": 250, "header": "tr|A0A5G2QWZ7-1|A0A5G2QWZ7_PIG Isoform 1 of Claudin OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QWZ7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ7/entry#A0A5G2QWZ7-1", "sequence": { "sequence": "MSDGGPEIHGKCSLPSGPSLAPDAPSSADGSPWSASTSPLFNGRLKLQLMGFVVATVGWVLGTTSMALAEWRVWYVNSTSLLSSHLACVGVWRACIFHQGNGLDRAIGCQGYSYFDPYIPMDIHVAQILLPLATVLGLFSKAAIIFALKSMYLSKVQKTCDPSAVAGMLSIAASFCILAAVVWNQLSIQTEEGIAFPPSFNLPFKPDSQEVGGAALMAFLGSCGLFFGGLAYFSYKYPLDSRVHPTTSDT", "length": 250, "header": "tr|A0A5G2QWZ7-1|A0A5G2QWZ7_PIG Isoform 1 of Claudin OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QWZ7-1" }, "locus": { "chromosome": "X", "start_pos": 6660890, "end_pos": 6657656, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077496.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077496.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069469.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069469.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ7" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QWZ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 250, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QWZ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QWZ7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R519-1", "uniprot_ac": "A0A5G2R519", "uniprot_id": "A0A5G2R519_PIG", "mass": { "chemical_mass": 138698.0, "monoisotopic_mass": 138698.0 }, "refseq": {}, "gene_names": [ { "name": "AP3D1", "type": "recommended", "evidence": [ { "id": "A0A5G2R519", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ] } ], "protein_names": [ { "name": "AP-3 complex subunit delta-1", "type": "recommended", "evidence": [ { "id": "A0A5G2R519", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519/entry#names_and_taxonomy" } ] }, { "name": "AP-3 complex subunit delta", "type": "synonym", "evidence": [ { "id": "A0A5G2R519", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519/entry#names_and_taxonomy" } ] }, { "name": "Adaptor-related protein complex 3 subunit delta-1", "type": "synonym", "evidence": [ { "id": "A0A5G2R519", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519/entry#names_and_taxonomy" } ] }, { "name": "Delta-adaptin", "type": "synonym", "evidence": [ { "id": "A0A5G2R519", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8H5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8H5#function" }, { "database": "UniProtKB", "id": "ARBA00055970", "url": "https://www.uniprot.org/uniprotkb/ARBA00055970#function" }, { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AP3D1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519", "locus": { "chromosome": "2", "start_pos": 76471257, "end_pos": 76428476, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040157", "url": "https://www.ensembl.org/id/ENSSSCG00000040157" } ] } } ], "crossref": [ { "id": "A0A5G2R519", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R519", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000040157", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000040157", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010474", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010474", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22781", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22781", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22781:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22781:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06375", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QX26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX26-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R519-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8H5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8H5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQCFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILRTHPKSVQAHKDLVLQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRRFAVSQMSALLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQDPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYAAILQQKEQAADAQAAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAKDMPVAEEVSALFAGELNPVAPKAQKKVPVPEGLDLDAWINEPLSDSESEDEKPKAIFQDEEQRHAKQRPPEADEQELARRREARKQEQANNPFYIKSSPSPQKRYQDAPGVDHIPVVQIDLSVPLKVPGMPMSDQYVKLEEERRHQQRLEKDKRKKKRRERERRGTRRHSSLHTESDEDIAPAQRVDIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPVQKHRNAETPKSPEKEDIPVIEKKSKKPKKKEKKHKEKEREKKKKRKEAEKGEDLDFWLSTTPPVAAPAPEEPRVNAAATAPEEGLEEPREEVQDADEDEHQEPEKKTSKEKKKKHKKDKEERPKDKKKSKKKTPPREGVAEPVENGALDEEPLPPMSSYCLLAENSYIKMTYDVQGSLQKDSQVTVSVVLENQSSSFLKSMELNVLDSLNARLARPEGSSVHDGVPVPFQLPPGISNEAQFVFTIQSIVMAQKLKGTLSFIAKNDEGSTHEKLDFKLHFTCTSYLVTTPCYSDAFAKLLESGDLSMSSIKVDGISMSFQNLLAKICFHHRFSVVERVDSCASMYSRSIQGHHVCLLVKKVSPQEGPTQPFHSSALCLCSFEPCSGGCWPILRSSGLGTGTSPTKWGGIPSSSLL", "length": 1232, "header": "tr|A0A5G2R519-1|A0A5G2R519_PIG Isoform 1 of AP-3 complex subunit delta-1 OS=Sus scrofa OX=9823 GN=AP3D1 PE=1 SV=1 CANONICAL=A0A5G2R519-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QX26-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519/entry#A0A5G2QX26-1", "sequence": { "sequence": "MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQCFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHRILIEDSDQNLKYLGLLAMSKILRTHPKSVQAHKDLVLQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRRFAVSQMSALLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQDPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYAAILQQKEQAADAQAAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAKDMPVAEEVSALFAGELNPVAPKAQKKVPVPEGLDLDAWINEPLSDSESEDEKPKAIFQDEEQRHAKQRPPEADEQELARRREARKQEQANNPFYIKSSPSPQKVRHGGRGLGPGPSTEYALFAGMPMSDQYVKLEEERRHQQRLEKDKRKKKRRERERRGTRRHSSLHTESDEDIAPAQRVDIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPVQKHRNAETPKSPEKEDIPVIEKKSKKPKKKEKKHKEKEREKKKKRKEAEKGEDLDFWLSTTPPVAAPAPEEPRVNAAATAPEEGLEEPREEVQDADEDEHQEPEKKTSKEKKKKHKKDKEERPKDKKKSKKKTPPREGVAEPVENGALDEEPLPPMSSYCLLAENSYIKMTYDVQGSLQKDSQVTVSVVLENQSSSFLKSMELNVLDSLNARLARPEGSSVHDGVPVPFQLPPGISNEAQFVFTIQSIVMAQKLKGTLSFIAKNDEGSTHEKLDFKLHFTCTSYLVTTPCYSDAFAKLLESGDLSMSSIKVDGISMSFQNLLAKICFHHRFSVVERVDSCASMYSRSIQGHHVCLLVKKVSPQEGPTQPFHSSALCLCSFEPCSGGCWPILRSSGLGTGTSPTKWGGIPSSSLL", "length": 1187, "header": "tr|A0A5G2QX26-1|A0A5G2R519_PIG Computationally mapped isoform of AP-3 complex subunit delta-1 OS=Sus scrofa OX=9823 GN=AP3D1 PE=1 SV=2 CANONICAL=A0A5G2R519-1" }, "locus": { "chromosome": "2", "start_pos": 76464986, "end_pos": 76428701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088590.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088590.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062740.2", "url": "https://www.ensembl.org/id/ENSSSCP00000062740.2" } ] } }, { "isoform_ac": "A0A5G2R519-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519/entry#A0A5G2R519-1", "sequence": { "sequence": "MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQCFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILRTHPKSVQAHKDLVLQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRRFAVSQMSALLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQDPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYAAILQQKEQAADAQAAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAKDMPVAEEVSALFAGELNPVAPKAQKKVPVPEGLDLDAWINEPLSDSESEDEKPKAIFQDEEQRHAKQRPPEADEQELARRREARKQEQANNPFYIKSSPSPQKRYQDAPGVDHIPVVQIDLSVPLKVPGMPMSDQYVKLEEERRHQQRLEKDKRKKKRRERERRGTRRHSSLHTESDEDIAPAQRVDIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPVQKHRNAETPKSPEKEDIPVIEKKSKKPKKKEKKHKEKEREKKKKRKEAEKGEDLDFWLSTTPPVAAPAPEEPRVNAAATAPEEGLEEPREEVQDADEDEHQEPEKKTSKEKKKKHKKDKEERPKDKKKSKKKTPPREGVAEPVENGALDEEPLPPMSSYCLLAENSYIKMTYDVQGSLQKDSQVTVSVVLENQSSSFLKSMELNVLDSLNARLARPEGSSVHDGVPVPFQLPPGISNEAQFVFTIQSIVMAQKLKGTLSFIAKNDEGSTHEKLDFKLHFTCTSYLVTTPCYSDAFAKLLESGDLSMSSIKVDGISMSFQNLLAKICFHHRFSVVERVDSCASMYSRSIQGHHVCLLVKKVSPQEGPTQPFHSSALCLCSFEPCSGGCWPILRSSGLGTGTSPTKWGGIPSSSLL", "length": 1232, "header": "tr|A0A5G2R519-1|A0A5G2R519_PIG Isoform 1 of AP-3 complex subunit delta-1 OS=Sus scrofa OX=9823 GN=AP3D1 PE=1 SV=1 CANONICAL=A0A5G2R519-1" }, "locus": { "chromosome": "2", "start_pos": 76464986, "end_pos": 76428701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077473.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077473.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065669.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065669.1" } ] } }, { "isoform_ac": "A0A5G2R8H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519/entry#A0A5G2R8H5-1", "sequence": { "sequence": "MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQCFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILRTHPKSVQAHKDLVLQCLDDKDESIRLRALDVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRRFAVSQMSALLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQDPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYAAILQQKEQAADAQAAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAKDMPVAEEVSALFAGELNPVAPKAQKKVPVPEGLDLDAWINEPLSDSESEDEKPKAIFQDEEQRHAKQRPPEADEQELARRREARKQEQANNPFYIKSSPSPQKRYQDAPGVDHIPVVQIDLSVPLKVPGMPMSDQYVKLEEERRHQQRLEKDKRKKKRRERERRGTRRHSSLHTESDEDIAPAQRVDIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPVQKHRNAETPKSPEKEDIPVIEKKSKKPKKKEKKHKEKEREKKKKRKEAEKKTSKEKKKKHKKDKEERPKDKKKSKKKTPPREGVAEPVENGALDEEPLPPMSSYCLLAENSYIKMTYDVQGSLQKDSQVTVSVVLENQSSSFLKSMELNVLDSLNARLARPEGSSVHDGVPVPFQLPPGISNEAQFVFTIQSIVMAQKLKGTLSFIAKNDEGSTHEKLDFKLHFTCTSYLVTTPCYSDAFAKLLESGDLSMSSIKVDGISMSFQNLLAKICFHHRFSVVERVDSCASMYSRSIQGHHVCLLVKKGEKSVSVDGKCSDPTLLSNLLEEMKETLAKC", "length": 1148, "header": "tr|A0A5G2R8H5-1|A0A5G2R519_PIG Computationally mapped isoform of AP-3 complex subunit delta-1 OS=Sus scrofa OX=9823 GN=AP3D1 PE=1 SV=1 CANONICAL=A0A5G2R519-1" }, "locus": { "chromosome": "2", "start_pos": 76470265, "end_pos": 76428701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071524.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071524.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070422.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070422.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1185, "start_aa": "Thr", "end_pos": 1185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1185", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX26", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX26" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "synaptic vesicle budding from endosome", "id": "GO:0016182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016182", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "endosome to melanosome transport", "id": "GO:0035646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035646", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "anterograde synaptic vesicle transport", "id": "GO:0048490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048490", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "synaptic vesicle membrane organization", "id": "GO:0048499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048499", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "neurotransmitter receptor transport, postsynaptic endosome to lysosome", "id": "GO:0098943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098943", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "zinc ion import into lysosome", "id": "GO:0140916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140916", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "lysosomal transport", "id": "GO:0007041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007041", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "AP-3 adaptor complex", "id": "GO:0030123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030123", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "presynaptic endosome", "id": "GO:0098830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098830", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R519", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1010, "end_pos": 1012, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R519-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1232, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R519-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R519" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R519", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R519" }, { "id": "SM01354", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01354" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-3 complex subunit delta", "eco_id": "ECO_0000259", "start_pos": 660, "end_pos": 807, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1185 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1010, "end_pos": 1012 }, { "start_pos": 296, "end_pos": 298 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QX30-1", "uniprot_ac": "A0A5G2QX30", "uniprot_id": "A0A5G2QX30_PIG", "mass": { "chemical_mass": 34918.0, "monoisotopic_mass": 34918.0 }, "refseq": { "ac": "XP_003480816", "name": "olfactory receptor 7A17-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480816" }, "gene_names": [ { "name": "LOC100738217", "type": "recommended", "evidence": [ { "id": "A0A5G2QX30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30" } ] }, { "name": "LOC100738217", "type": "synonym", "evidence": [ { "id": "XP_003480816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480816" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QX30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7A17-like", "type": "synonym", "evidence": [ { "id": "XP_003480816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480816" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100738217", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30", "locus": {} } ], "crossref": [ { "id": "A0A5G2QX30", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX30", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100738217", "url": "https://www.ncbi.nlm.nih.gov/gene/100738217", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100738217", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738217", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNPHLCK", "url": "https://omabrowser.org/oma/group/MNPHLCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QX30", "url": "https://www.orthodb.org/?gene=A0A5G2QX30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003480816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480816", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QX30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX30-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDIFLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWVMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAASLLCGGPFFGILCSYSKIVSSICRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVTGPM", "length": 310, "header": "tr|A0A5G2QX30-1|A0A5G2QX30_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100738217 PE=3 SV=1 CANONICAL=A0A5G2QX30-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QX30-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30/entry#A0A5G2QX30-1", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDIFLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWVMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAASLLCGGPFFGILCSYSKIVSSICRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVTGPM", "length": 310, "header": "tr|A0A5G2QX30-1|A0A5G2QX30_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100738217 PE=3 SV=1 CANONICAL=A0A5G2QX30-1" }, "locus": { "chromosome": "AEMK02000630.1", "start_pos": 80910, "end_pos": 79981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079984.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079984.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066494.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066494.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100738217", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738217", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MY48-1", "protein_name": "Olfactory receptor", "gene_name": "OR7A96", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQPGNDTWISGFLLLRFSEEPEVQPLIFGLFLSMYLLTVFGNLLIILAVSSDANLHTPMYFFLSNLSFVDICFTSTTIPKMLWNIQTQNKAITYEGCITQIYFFTLSAVLDIFLLTVMAYDRFVAICHPLHYTVIMNPRLCALLVLMSWIICLLNSLLQSLMVLRLSFCTNLKIPHFFCELNQMIQLACSDTFLNNMVMYFAAVLMGGGPFTGVLYSYSKIVSCIRGISSLQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAGTHSSRSSATASVMYTVVTPMLNPFIYSLRNKDIKRALKAFFVKQTTE", "length": 311 }, "evidence": [ { "id": "A0A5G2QX30", "url": "https://omabrowser.org/oma/group/A0A5G2QX30/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX30", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QX30-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QX30-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX30" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QX30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX30" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QX31-1", "uniprot_ac": "A0A5G2QX31", "uniprot_id": "A0A5G2QX31_PIG", "mass": { "chemical_mass": 45478.0, "monoisotopic_mass": 45478.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QX31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX31/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX31" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX31", "locus": {} } ], "crossref": [ { "id": "A0A5G2QX31", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX31", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041323", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041323", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QX31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX31-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "TAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASLLQGCNKKRSRTGGNVDNHNSDVVAETRGEDAFSTSTNLNVPLIGWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQNVMAQHAIFSQLTMFHMHSQSSYSPASGHIVNFIKTTTSISQYRHISNFPSGYFGLRVEPSPLPTRYQNISPTEGPLSNPQPAALPWFPMPMATDTSAASLSRQNPQSSSVSEHHPNFHCPIKGL", "length": 408, "header": "tr|A0A5G2QX31-1|A0A5G2QX31_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QX31-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QX31-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX31/entry#A0A5G2QX31-1", "sequence": { "sequence": "TAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASLLQGCNKKRSRTGGNVDNHNSDVVAETRGEDAFSTSTNLNVPLIGWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQNVMAQHAIFSQLTMFHMHSQSSYSPASGHIVNFIKTTTSISQYRHISNFPSGYFGLRVEPSPLPTRYQNISPTEGPLSNPQPAALPWFPMPMATDTSAASLSRQNPQSSSVSEHHPNFHCPIKGL", "length": 408, "header": "tr|A0A5G2QX31-1|A0A5G2QX31_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QX31-1" }, "locus": { "chromosome": "Y", "start_pos": 20853045, "end_pos": 20851399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073902.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073902.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062745.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062745.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 356, "start_aa": "Thr", "end_pos": 356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr356", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX31" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX31" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QX31-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 408, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QX31-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX31" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QX31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX31" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 356 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2QX37-1", "uniprot_ac": "A0A5G2QX37", "uniprot_id": "A0A5G2QX37_PIG", "mass": { "chemical_mass": 35335.0, "monoisotopic_mass": 35335.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Taste receptor type 2", "type": "recommended", "evidence": [ { "id": "A0A5G2QX37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX37/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX37" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX37", "locus": {} } ], "crossref": [ { "id": "A0A5G2QX37", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX37", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044781", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044781", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13950", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13950", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11394:SF138", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11394:SF138", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05296", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05296", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QX37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX37-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNVLEKVFMTVTGGELIIGILGNGFIGLTTFIAWIRNQKLCLVDFILTSLAFARISQLWLTVANLFSVLLYQEGFGTVERNYVLASSLILANHLSIWLATCLVVFYFLKIASFSNLPFLWLKRRIKKVVFILLLLSVPFLFMSFPFPYSFDGFWYHTQNILERNITELYNVTQSQKLKFMLIFTAGSIPPFSLSLISFFLLLCSLWKHKKHIELSVSDSRDASMEAHFRAMRTVFFFLVFFALYHLAFFMTFGGHFLLVTTFIIIENVAFLYPSIHPFILILGNQKLRQTFASLLRQIESCLKGM", "length": 306, "header": "tr|A0A5G2QX37-1|A0A5G2QX37_PIG Isoform 1 of Taste receptor type 2 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QX37-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QX37-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX37/entry#A0A5G2QX37-1", "sequence": { "sequence": "MLNVLEKVFMTVTGGELIIGILGNGFIGLTTFIAWIRNQKLCLVDFILTSLAFARISQLWLTVANLFSVLLYQEGFGTVERNYVLASSLILANHLSIWLATCLVVFYFLKIASFSNLPFLWLKRRIKKVVFILLLLSVPFLFMSFPFPYSFDGFWYHTQNILERNITELYNVTQSQKLKFMLIFTAGSIPPFSLSLISFFLLLCSLWKHKKHIELSVSDSRDASMEAHFRAMRTVFFFLVFFALYHLAFFMTFGGHFLLVTTFIIIENVAFLYPSIHPFILILGNQKLRQTFASLLRQIESCLKGM", "length": 306, "header": "tr|A0A5G2QX37-1|A0A5G2QX37_PIG Isoform 1 of Taste receptor type 2 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QX37-1" }, "locus": { "chromosome": "5", "start_pos": 61234216, "end_pos": 61227816, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091318.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091318.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069436.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069436.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX37" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX37" } ], "pmid": "" }, { "name": "bitter taste receptor activity", "id": "GO:0033038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033038", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX37" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of bitter taste", "id": "GO:0001580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001580", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QX37-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 306, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QX37-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX37" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 171, "end_pos": 173 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QX38-1", "uniprot_ac": "A0A5G2QX38", "uniprot_id": "A0A5G2QX38_PIG", "mass": { "chemical_mass": 35139.0, "monoisotopic_mass": 35139.0 }, "refseq": { "ac": "XP_020937079", "name": "olfactory receptor 6C2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937079" }, "gene_names": [ { "name": "LOC110258236", "type": "recommended", "evidence": [ { "id": "A0A5G2QX38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38" } ] }, { "name": "LOC110258236", "type": "synonym", "evidence": [ { "id": "XP_020937079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937079" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QX38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6C2-like", "type": "synonym", "evidence": [ { "id": "XP_020937079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937079" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110258236", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38", "locus": {} } ], "crossref": [ { "id": "A0A5G2QX38", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX38", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110258236", "url": "https://www.ncbi.nlm.nih.gov/gene/110258236", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110258236", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258236", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICCWMAG", "url": "https://omabrowser.org/oma/group/ICCWMAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QX38", "url": "https://www.orthodb.org/?gene=A0A5G2QX38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020937079", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937079", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QX38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX38-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLTYTLSVTGNLTIITLTFVDSHLKTPMYFFLKNYSFLEISLTTACVPRYLYSIATGDKVITYNACFIQVFFTDLCGVIEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKKAFKDSIKRIALLSTK", "length": 311, "header": "tr|A0A5G2QX38-1|A0A5G2QX38_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258236 PE=3 SV=1 CANONICAL=A0A5G2QX38-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QX38-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38/entry#A0A5G2QX38-1", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLTYTLSVTGNLTIITLTFVDSHLKTPMYFFLKNYSFLEISLTTACVPRYLYSIATGDKVITYNACFIQVFFTDLCGVIEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKKAFKDSIKRIALLSTK", "length": 311, "header": "tr|A0A5G2QX38-1|A0A5G2QX38_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258236 PE=3 SV=1 CANONICAL=A0A5G2QX38-1" }, "locus": { "chromosome": "AEMK02000640.1", "start_pos": 113152, "end_pos": 112220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072485.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072485.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069504.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069504.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110258236", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258236", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QX38-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QX38-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX38" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QX38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX38" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QX54-1", "uniprot_ac": "A0A5G2QX54", "uniprot_id": "A0A5G2QX54_PIG", "mass": { "chemical_mass": 49744.0, "monoisotopic_mass": 49744.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100158003", "type": "recommended", "evidence": [ { "id": "A0A5G2QX54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ] } ], "protein_names": [ { "name": "Tubulin alpha chain", "type": "recommended", "evidence": [ { "id": "A0A5G2QX54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54#function" }, { "database": "UniProtKB", "id": "RU000352", "url": "https://www.uniprot.org/uniprotkb/RU000352#function" }, { "database": "UniProtKB", "id": "F1SR80", "url": "https://www.uniprot.org/uniprotkb/F1SR80#function" } ] }, { "annotation": "Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54#function" }, { "database": "UniProtKB", "id": "ARBA00093431", "url": "https://www.uniprot.org/uniprotkb/ARBA00093431#function" }, { "database": "UniProtKB", "id": "F1SR80", "url": "https://www.uniprot.org/uniprotkb/F1SR80#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100158003", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54", "locus": {} } ], "crossref": [ { "id": "A0A5G2QX54", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX54", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016215", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016215", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02186", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02186", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "9CPC", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CPC&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR000217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017975", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017975", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11588", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11588", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00009cpc", "url": "https://www.rcsb.org/structure/pdb_00009cpc", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CPC", "url": "https://www.rcsb.org/structure/9CPC", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX54-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SR80", "url": "https://www.uniprot.org/uniprotkb/F1SR80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SR80-1", "url": "https://www.uniprot.org/uniprotkb/F1SR80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QRECISVHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKELIDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGMDSVEGEGEEEE", "length": 447, "header": "tr|A0A5G2QX54-1|A0A5G2QX54_PIG Isoform 1 of Tubulin alpha chain OS=Sus scrofa OX=9823 GN=LOC100158003 PE=1 SV=2 CANONICAL=A0A5G2QX54-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QX54-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54/entry#A0A5G2QX54-1", "sequence": { "sequence": "QRECISVHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKELIDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGMDSVEGEGEEEE", "length": 447, "header": "tr|A0A5G2QX54-1|A0A5G2QX54_PIG Isoform 1 of Tubulin alpha chain OS=Sus scrofa OX=9823 GN=LOC100158003 PE=1 SV=2 CANONICAL=A0A5G2QX54-1" }, "locus": { "chromosome": "15", "start_pos": 121311850, "end_pos": 121309495, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091074.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091074.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068730.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068730.2" } ] } }, { "isoform_ac": "F1SR80-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54/entry#F1SR80-1", "sequence": { "sequence": "MILHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKELIDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGMDSVEGEGEEEEGDEY", "length": 437, "header": "tr|F1SR80-1|F1SR80_PIG Computationally mapped isoform of Tubulin alpha chain OS=Sus scrofa OX=9823 GN=LOC100158003 PE=3 SV=3 CANONICAL=A0A5G2QX54-1" }, "locus": { "chromosome": "15", "start_pos": 121311862, "end_pos": 121309464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017657.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017657.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017179.4", "url": "https://www.ensembl.org/id/ENSSSCP00000017179.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Structural diversity of axonemes across mammalian motile cilia.", "journal": "Nature", "date": "2025", "authors": "Leung Miguel Ricardo, Sun Chen, Zeng Jianwei, Anderson Jacob R, Niu Qingwei, Huang Wei, Noteborn Willem E M, Brown Alan, Zeev-Ben-Mordehai Tzviya, Zhang Rui", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ], "reference": [ { "type": "PubMed", "id": "39743588", "url": "https://glygen.org/publication/PubMed/39743588" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ], "pmid": "" }, { "name": "microtubule-based process", "id": "GO:0007017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX54", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QX54-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 447, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QX54-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX54" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QX54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" }, { "id": "SM00865", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubulin/FtsZ 2-layer sandwich", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 392, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QX54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX54" }, { "id": "SM00864", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00864" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubulin/FtsZ GTPase", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 246, "start_aa": "Phe", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 379, "end_pos": 381 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QX80-1", "uniprot_ac": "A0A5G2QX80", "uniprot_id": "A0A5G2QX80_PIG", "mass": { "chemical_mass": 43159.0, "monoisotopic_mass": 43159.0 }, "refseq": {}, "gene_names": [ { "name": "YJU2", "type": "recommended", "evidence": [ { "id": "A0A5G2QX80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80" } ] } ], "protein_names": [ { "name": "Splicing factor YJU2", "type": "recommended", "evidence": [ { "id": "A0A5G2QX80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80#function" }, { "database": "HAMAP", "id": "MF_03226", "url": "https://hamap.expasy.org/signature/MF_03226" }, { "database": "UniProtKB", "id": "F1S7N8", "url": "https://www.uniprot.org/uniprotkb/F1S7N8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "YJU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80", "locus": { "chromosome": "2", "start_pos": 74509739, "end_pos": 74528300, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013499", "url": "https://www.ensembl.org/id/ENSSSCG00000013499" } ] } } ], "crossref": [ { "id": "A0A5G2QX80", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX80", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013499", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013499", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12111", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12111", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12111:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12111:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04502", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04502", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QX80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX80-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S7N8", "url": "https://www.uniprot.org/uniprotkb/F1S7N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S7N8-1", "url": "https://www.uniprot.org/uniprotkb/F1S7N8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQNEAYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERQKREQEEDERETAALVEESRKRRLLEDSDSEEDAAPTQPWPALPPNPTAILDEATPSVYGDSQARGQIGATAASLHHSSRQRQILNPLSEGRDQTHNLMFTRSIHFCCSTMAPKAKRKVESWERSVGTLGSRPQLSRLVVVKKTDLDRSIQRGLAPPSAVMNGKTAEPSPQAPGPSSLSQLGVYSDSEDSSGSN", "length": 377, "header": "tr|A0A5G2QX80-1|A0A5G2QX80_PIG Isoform 1 of Splicing factor YJU2 OS=Sus scrofa OX=9823 GN=YJU2 PE=3 SV=1 CANONICAL=A0A5G2QX80-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QX80-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80/entry#A0A5G2QX80-1", "sequence": { "sequence": "MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQNEAYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERQKREQEEDERETAALVEESRKRRLLEDSDSEEDAAPTQPWPALPPNPTAILDEATPSVYGDSQARGQIGATAASLHHSSRQRQILNPLSEGRDQTHNLMFTRSIHFCCSTMAPKAKRKVESWERSVGTLGSRPQLSRLVVVKKTDLDRSIQRGLAPPSAVMNGKTAEPSPQAPGPSSLSQLGVYSDSEDSSGSN", "length": 377, "header": "tr|A0A5G2QX80-1|A0A5G2QX80_PIG Isoform 1 of Splicing factor YJU2 OS=Sus scrofa OX=9823 GN=YJU2 PE=3 SV=1 CANONICAL=A0A5G2QX80-1" }, "locus": { "chromosome": "2", "start_pos": 74528223, "end_pos": 74511943, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072636.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072636.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068755.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068755.1" } ] } }, { "isoform_ac": "F1S7N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80/entry#F1S7N8-1", "sequence": { "sequence": "MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQNEAYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERQKREQEEDERETAALVEESRKRRLLEDSDSEEDAAPTQPWPALPPNPTAILDEAPKAKRKVESWERSVGTLGSRPQLSRLVVVKKTDLDRSIQRGLAPPTVPPVRFLSL", "length": 292, "header": "tr|F1S7N8-1|F1S7N8_PIG Computationally mapped isoform of Splicing factor YJU2 OS=Sus scrofa OX=9823 GN=YJU2 PE=3 SV=4 CANONICAL=A0A5G2QX80-1" }, "locus": { "chromosome": "2", "start_pos": 74528223, "end_pos": 74513291, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014745.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014745.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014347.4", "url": "https://www.ensembl.org/id/ENSSSCP00000014347.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "generation of catalytic spliceosome for first transesterification step", "id": "GO:0000349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000349", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80" } ], "pmid": "" }, { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QX80-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 377, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QX80-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QX80" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A5G2QX80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80#function" }, { "id": "A0A5G2QX80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80" }, { "id": "MF_03226", "database": "HAMAP", "url": "https://hamap.expasy.org/signature/MF_03226" }, { "id": "F1S7N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S7N8#function" }, { "id": "F1S7N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S7N8" } ], "binding_site_uniprot": 43, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 43, "end_pos": 43, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QX80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80#function" }, { "id": "A0A5G2QX80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80" }, { "id": "MF_03226", "database": "HAMAP", "url": "https://hamap.expasy.org/signature/MF_03226" }, { "id": "F1S7N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S7N8#function" }, { "id": "F1S7N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S7N8" } ], "binding_site_uniprot": 46, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 46, "end_pos": 46, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QX80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80#function" }, { "id": "A0A5G2QX80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80" }, { "id": "MF_03226", "database": "HAMAP", "url": "https://hamap.expasy.org/signature/MF_03226" }, { "id": "F1S7N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S7N8#function" }, { "id": "F1S7N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S7N8" } ], "binding_site_uniprot": 80, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 80, "end_pos": 80, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QX80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80#function" }, { "id": "A0A5G2QX80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX80" }, { "id": "MF_03226", "database": "HAMAP", "url": "https://hamap.expasy.org/signature/MF_03226" }, { "id": "F1S7N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S7N8#function" }, { "id": "F1S7N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S7N8" } ], "binding_site_uniprot": 83, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 83, "end_pos": 83, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXC2-1", "uniprot_ac": "A0A5G2QXC2", "uniprot_id": "A0A5G2QXC2_PIG", "mass": { "chemical_mass": 135593.0, "monoisotopic_mass": 135593.0 }, "refseq": {}, "gene_names": [ { "name": "PCDH7", "type": "recommended", "evidence": [ { "id": "A0A5G2QXC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2" } ] } ], "protein_names": [ { "name": "Protocadherin 7", "type": "synonym", "evidence": [ { "id": "A0A5G2QXC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PCDH7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2", "locus": { "chromosome": "8", "start_pos": 23873007, "end_pos": 23459475, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008765", "url": "https://www.ensembl.org/id/ENSSSCG00000008765" } ] } } ], "crossref": [ { "id": "A0A5G2QXC2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008765", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008765", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08374", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08374", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013026", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013026", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QXC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8K0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRMRTMGWARAWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDFEGRVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGGGGGEGRRAGPADSAPYPGGGGNGASGGGPGGSKRRLDAPEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSAPLDYETTREYNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPVFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDIFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENSNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPRNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVNATVIDSQIARSLHTPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSVVSQPQDPHQGSLQSCYDSGLEESETPSSKSSSGPRLGALPLPEDNYERTTPDGSVDSIPLPDVALTGKCTRECDEYGHSDSCWMPVRTSPERKKSQPKLSTFMPVDERGSQEKLANGEAAIMGDRNRNLLNKKLTSSYETFSAASFSKNEEANTEDIPLTKTGEYKPSPVNTLTRREVYL", "length": 1246, "header": "tr|A0A5G2QXC2-1|A0A5G2QXC2_PIG Isoform 1 of Protocadherin 7 OS=Sus scrofa OX=9823 GN=PCDH7 PE=1 SV=1 CANONICAL=A0A5G2QXC2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QXC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2/entry#A0A5G2QXC2-1", "sequence": { "sequence": "MLRMRTMGWARAWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDFEGRVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGGGGGEGRRAGPADSAPYPGGGGNGASGGGPGGSKRRLDAPEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSAPLDYETTREYNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPVFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDIFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENSNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPRNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVNATVIDSQIARSLHTPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSVVSQPQDPHQGSLQSCYDSGLEESETPSSKSSSGPRLGALPLPEDNYERTTPDGSVDSIPLPDVALTGKCTRECDEYGHSDSCWMPVRTSPERKKSQPKLSTFMPVDERGSQEKLANGEAAIMGDRNRNLLNKKLTSSYETFSAASFSKNEEANTEDIPLTKTGEYKPSPVNTLTRREVYL", "length": 1246, "header": "tr|A0A5G2QXC2-1|A0A5G2QXC2_PIG Isoform 1 of Protocadherin 7 OS=Sus scrofa OX=9823 GN=PCDH7 PE=1 SV=1 CANONICAL=A0A5G2QXC2-1" }, "locus": { "chromosome": "8", "start_pos": 23872003, "end_pos": 23459475, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009590.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009590.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066584.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066584.1" } ] } }, { "isoform_ac": "A0A5G2R8K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2/entry#A0A5G2R8K0-1", "sequence": { "sequence": "MLRMRTMGWARAWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDFEGRVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGGGGGEGRRAGPADSAPYPGGGGNGASGGGPGGSKRRLDAPEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSAPLDYETTREYNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPVFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDIFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENSNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPRNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVNATVIDSQIARSLHTPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQMRLHPYITVFG", "length": 1068, "header": "tr|A0A5G2R8K0-1|A0A5G2R8K0_PIG Computationally mapped isoform of Protocadherin 7 OS=Sus scrofa OX=9823 GN=PCDH7 PE=1 SV=1 CANONICAL=A0A5G2QXC2-1" }, "locus": { "chromosome": "8", "start_pos": 23468902, "end_pos": 23459475, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079445.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079445.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066938.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066938.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" }, { "id": "R-SSC-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-SSC-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1035, "end_pos": 1037, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 780, "end_pos": 782, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" }, { "start_pos": 822, "end_pos": 824, "annotation": "n_glycosylation_sequon" }, { "start_pos": 840, "end_pos": 842, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QXC2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1246, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QXC2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXC2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QXC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXC2" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 142, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1035, "end_pos": 1037 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 689, "end_pos": 691 }, { "start_pos": 747, "end_pos": 749 }, { "start_pos": 780, "end_pos": 782 }, { "start_pos": 79, "end_pos": 81 }, { "start_pos": 822, "end_pos": 824 }, { "start_pos": 840, "end_pos": 842 }, { "start_pos": 844, "end_pos": 846 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXD3-1", "uniprot_ac": "A0A5G2QXD3", "uniprot_id": "A0A5G2QXD3_PIG", "mass": { "chemical_mass": 49709.0, "monoisotopic_mass": 49709.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100515166", "type": "recommended", "evidence": [ { "id": "A0A5G2QXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" } ] } ], "protein_names": [ { "name": "Keratin 15", "type": "synonym", "evidence": [ { "id": "A0A5G2QXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100515166", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3", "locus": {} } ], "crossref": [ { "id": "A0A5G2QXD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017445", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017445", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100515166", "url": "https://www.ncbi.nlm.nih.gov/gene/100515166", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515166", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515166", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DAKMTGF", "url": "https://omabrowser.org/oma/group/DAKMTGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RAS7", "url": "https://www.orthodb.org/?gene=A0A5G2RAS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QXD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAS7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0K1", "url": "https://www.uniprot.org/uniprotkb/F1S0K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0K1-1", "url": "https://www.uniprot.org/uniprotkb/F1S0K1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCRLQSSSASYGGGFGGGSCQLGGGRSISTCSSRFVSGGSTGGYGGGVSCGFGGGAGSGFGAGFGGGFGGSFGGGFGGGVAGGFGFGDFGGGDGGLLAGNEKITMQNLNDRLASYLEKVRALEEANTDLEVKIRDWYQKQSPSSPERDYSPYFKTIEELRDKIQAANIENNRVVLQIDNARLAADDFRLKYENELTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLNEELAFLKKNHEEEMKEFSNRVVGQVNVEMDATPGVDLTRVLAEMREQYEAMAEKNRREAEEWFNKKIEELNKEVISSTALIQTSKTEITELRRTLQGLEIELQSQLSTKAGLENSLAETECRYALQLQQIQGLIGSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDANLNVFCSLRFPGNVTHSATITASTTISSSGSSNGPTRRTLESSRS", "length": 457, "header": "tr|A0A5G2QXD3-1|A0A5G2QXD3_PIG Isoform 1 of Keratin 15 OS=Sus scrofa OX=9823 GN=LOC100515166 PE=1 SV=2 CANONICAL=A0A5G2QXD3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QXD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3/entry#A0A5G2QXD3-1", "sequence": { "sequence": "MSCRLQSSSASYGGGFGGGSCQLGGGRSISTCSSRFVSGGSTGGYGGGVSCGFGGGAGSGFGAGFGGGFGGSFGGGFGGGVAGGFGFGDFGGGDGGLLAGNEKITMQNLNDRLASYLEKVRALEEANTDLEVKIRDWYQKQSPSSPERDYSPYFKTIEELRDKIQAANIENNRVVLQIDNARLAADDFRLKYENELTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLNEELAFLKKNHEEEMKEFSNRVVGQVNVEMDATPGVDLTRVLAEMREQYEAMAEKNRREAEEWFNKKIEELNKEVISSTALIQTSKTEITELRRTLQGLEIELQSQLSTKAGLENSLAETECRYALQLQQIQGLIGSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDANLNVFCSLRFPGNVTHSATITASTTISSSGSSNGPTRRTLESSRS", "length": 457, "header": "tr|A0A5G2QXD3-1|A0A5G2QXD3_PIG Isoform 1 of Keratin 15 OS=Sus scrofa OX=9823 GN=LOC100515166 PE=1 SV=2 CANONICAL=A0A5G2QXD3-1" }, "locus": { "chromosome": "12", "start_pos": 21143352, "end_pos": 21139382, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066749.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066749.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069594.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069594.2" } ] } }, { "isoform_ac": "A0A5G2RAS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3/entry#A0A5G2RAS7-1", "sequence": { "sequence": "MSCRLQSSSASYGGGFGGGSCQLGGGRSISTCSSRFVSGGSTGGYGGGVSCGFGGGAGSGFGAGFGGGFGGSFGGGFGGGVAGGFGFGDFGGGDGGLLAGNEKITMQNLNDRLASYLEKVRALEEANTDLEVKIRDWYQKQSPSSPERDYSPYFKTIEELRDKIQAANIENNRVVLQIDNARLAADDFRLKYENELTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLNEELAFLKKNHEEEMKEFSNRVVGQVNVEMDATPGVDLTRVLAEMREQYEAMAEKNRREAEEWFNKKIEELNKEVISSTALIQTSKTEITELRRTLQGLEIELQSQLSTKAGLENSLAETECRYALQLQQIQGLIGSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKLTGFATGGNVTHSATITASTTISSSGSSNGPTRRTLESSRS", "length": 454, "header": "tr|A0A5G2RAS7-1|A0A5G2RAS7_PIG Computationally mapped isoform of Keratin 15 OS=Sus scrofa OX=9823 GN=LOC100515166 PE=1 SV=1 CANONICAL=A0A5G2QXD3-1" }, "locus": { "chromosome": "12", "start_pos": 21143352, "end_pos": 21139382, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068642.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068642.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074112.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074112.1" } ] } }, { "isoform_ac": "F1S0K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3/entry#F1S0K1-1", "sequence": { "sequence": "MSCRLQSSSASYGGGFGGGSCQLGGGRSISTCSSRFVSGGSTGGYGGGVSCGFGGGAGSGFGAGFGGGFGGSFGGGFGGGVAGGFGFGDFGGGDGGLLAGNEKITMQNLNDRLASYLEKVRALEEANTDLEVKIRDWYQKQSPSSPERDYSPYFKTIEELRDKIQAANIENNRVVLQIDNARLAADDFRLKYENELTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLNEELAFLKKNHEEEMKEFSNRVVGQVNVEMDATPGVDLTRVLAEMREQYEAMAEKNRREAEEWFNKKIEELNKEVISSTALIQTSKTEITELRRTLQGLEIELQSQLSTKAGLENSLAETECRYALQLQQIQGLIGSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDSNLAGGGGPSN", "length": 422, "header": "tr|F1S0K1-1|A0A5G2QXD3_PIG Computationally mapped isoform of Keratin 15 OS=Sus scrofa OX=9823 GN=LOC100515166 PE=1 SV=2 CANONICAL=A0A5G2QXD3-1" }, "locus": { "chromosome": "12", "start_pos": 21142820, "end_pos": 21139382, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018991.3", "url": "https://www.ensembl.org/id/ENSSSCT00000018991.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018486.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018486.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0K1", "url": "https://www.uniprot.org/uniprotkb/F1S0K1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515166", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515166", "resource": "KEGG Pathway" }, { "id": "R-SSC-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-SSC-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZK24-1", "protein_name": "Keratin 13", "gene_name": "KRT13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTTYTVQNSFASGAGGLGAAGSGSSRLSSVRVGGSYRTPSIHGGSGGRGVSISSTKYVSSVGGGYGGGSCAGFGGGYGGGYGGFGGGAVCGLGGGAGFGGGFDAICAFGGGDGLLSGNEKITMQNLNDRLATYLQKVRALEDANAELEVKIRDWYQKEAPSSPARDYSNYYKIIEDLQDKILAATIDNSRVVLEIDNARLAADDFRLKHENELFLRQSVESDINGLRRVLDELTLSRADLEMQIESLKEELAYLKKNHEEEMKEYSNQLSGKVSVEMDAAPGIDLTRILSEMREQYEALAEKYRKDAEAWFLTQTTELNHEVATHTEQIQSSKSEITELRRTMQSLEIELQSQISMKAGLEANLRDTEGRYCAQLAQIQNLITSVEEQLSEIRCDMERQNQEYRMLMDIKSRLEQEIATYRQLLETQDSHLMIFFSPTTASAAGRARGGTEDEGRSSSTRDRRHQ", "length": 465 }, "evidence": [ { "id": "A0A5G2QXD3", "url": "https://omabrowser.org/oma/group/A0A5G2QXD3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3I8F5-1", "protein_name": "Keratin, type I cytoskeletal 13", "gene_name": "Krt13", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSCRFQSSSTSYGGGFGAGSCQLGGGRKISTCSSRFASGGSAGGYGGGMSCGFGGGAGSGFGGGFGGSYGGGFGGGFGGGFGGGFGDFGGGDGGLLSGNEKITMQNLNDRLANYLEKVRALEAANADLEVKIRDWHLRQSPTSPERDYSAYYKTIEELRVKILEATTDNNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYLKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEALAEKNRRDAEQWFQNKSAELNKEVSSNAAMIQTSKTEITELRRTLQSLEIELQSQLSMKAGLESTLAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMTGFNNSGGTSTASNASSSPSTSGRLDFRKY", "length": 442 }, "evidence": [ { "id": "A0A5G2QXD3", "url": "https://omabrowser.org/oma/group/A0A5G2QXD3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P08730-1", "protein_name": "Keratin, type I cytoskeletal 13", "gene_name": "Krt13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCRFQSSSMSYGGGFGAGSCQLGGGRNISSCSSRFVTGGSAGGYGGGMSCGFGGGAGGGFGGGFGGGFGGSYGGGFGGGFGDFGGVDGGLLSGNEKITMQNLNDRLASYLDKVRALEAANADLEVKIRDWHLKQSPASPERDYSAYYKTIEELRIKILEATTDNNRIILEIDNARLAADDFRLKYENELTLRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYLKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEALAEKNRRDAEEWFQTKSAELNKEVSSNAEMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLESTLAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMTGFNSGGNNTTTSNGSPSSNSGRPDFRKY", "length": 437 }, "evidence": [ { "id": "A0A5G2QXD3", "url": "https://omabrowser.org/oma/group/A0A5G2QXD3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13646-1", "protein_name": "Keratin, type I cytoskeletal 13", "gene_name": "KRT13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHTKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGRRTSDVRRP", "length": 458 }, "evidence": [ { "id": "A0A5G2QXD3", "url": "https://omabrowser.org/oma/group/A0A5G2QXD3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6IFV4-1", "protein_name": "Keratin, type I cytoskeletal 13", "gene_name": "Krt13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSCRFQSSSMSYGGGFGAGSCQLGGGRNISTCSSRFVTGGSSGGYGGGMSCGFGGGAGGGYGGGFGGGFGGSCGGGFGGGFGDFGSVDGGLLSGNEKITMQNLNDRLASYLEKVRALEAANADLEVKIRDWHLKQSPTSPERDYSAYYKTIEELRIKILEATTDNNRIVLEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYLKKNHEEEMKEFSNQAVGQVNVEMDATPGIDLTRVLAEMREQYEALAEKNRRDAEAWFQAKSAELNKEVSSNAAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLESTLAETECRYALQLQQIQALISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMTGFNTGGNSTTTSNTSTSPSTSGRPDFRKY", "length": 438 }, "evidence": [ { "id": "A0A5G2QXD3", "url": "https://omabrowser.org/oma/group/A0A5G2QXD3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of translation in response to stress", "id": "GO:0043555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043555", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" } ], "pmid": "" }, { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" } ], "pmid": "" }, { "name": "morphogenesis of an epithelium", "id": "GO:0002009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" } ], "pmid": "" }, { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QXD3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 457, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QXD3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXD3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXD3" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 102, "end_pos": 414, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 425, "end_pos": 427 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXJ2-1", "uniprot_ac": "A0A5G2QXJ2", "uniprot_id": "A0A5G2QXJ2_PIG", "mass": { "chemical_mass": 25294.0, "monoisotopic_mass": 25294.0 }, "refseq": { "ac": "XP_005653637", "name": "meiotic nuclear division protein 1 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653637" }, "gene_names": [ { "name": "MND1", "type": "recommended", "evidence": [ { "id": "A0A5G2QXJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2" } ] }, { "name": "MND1", "type": "synonym", "evidence": [ { "id": "XP_005653637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653637" } ] } ], "protein_names": [ { "name": "Meiotic nuclear division protein 1 homolog", "type": "recommended", "evidence": [ { "id": "A0A5G2QXJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2/entry#names_and_taxonomy" } ] }, { "name": "meiotic nuclear division protein 1 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005653637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653637" } ] } ], "function": [ { "annotation": "Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2#function" }, { "database": "UniProtKB", "id": "PIRNR026991", "url": "https://www.uniprot.org/uniprotkb/PIRNR026991#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MND1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2", "locus": { "chromosome": "8", "start_pos": 75689845, "end_pos": 75755768, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009009", "url": "https://www.ensembl.org/id/ENSSSCG00000009009" } ] } } ], "crossref": [ { "id": "A0A5G2QXJ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009009", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009009", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100517105", "url": "https://www.ncbi.nlm.nih.gov/gene/100517105", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QXJ2", "url": "https://www.orthodb.org/?gene=A0A5G2QXJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31398", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31398", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31398:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31398:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005653637", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653637", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QXJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCFSPLVTASVLSISSKKKGLSAEEKRARMMEIFFETKDVFQLKDMEKIAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHTRKRKLEVLESQLSEGNQKHANLQKSIEKAKIGRHETEERTMLAKELSSLRDQKEQLKAEVEKYKECDPQVVEEMRQANKVAKEAANRWTDNIFAVKSWAKRKFGFEENKIDKNFGIPEDFDYID", "length": 219, "header": "tr|A0A5G2QXJ2-1|A0A5G2QXJ2_PIG Isoform 1 of Meiotic nuclear division protein 1 homolog OS=Sus scrofa OX=9823 GN=MND1 PE=3 SV=1 CANONICAL=A0A5G2QXJ2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QXJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2/entry#A0A5G2QXJ2-1", "sequence": { "sequence": "MCFSPLVTASVLSISSKKKGLSAEEKRARMMEIFFETKDVFQLKDMEKIAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHTRKRKLEVLESQLSEGNQKHANLQKSIEKAKIGRHETEERTMLAKELSSLRDQKEQLKAEVEKYKECDPQVVEEMRQANKVAKEAANRWTDNIFAVKSWAKRKFGFEENKIDKNFGIPEDFDYID", "length": 219, "header": "tr|A0A5G2QXJ2-1|A0A5G2QXJ2_PIG Isoform 1 of Meiotic nuclear division protein 1 homolog OS=Sus scrofa OX=9823 GN=MND1 PE=3 SV=1 CANONICAL=A0A5G2QXJ2-1" }, "locus": { "chromosome": "8", "start_pos": 75755738, "end_pos": 75689988, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067865.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067865.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069596.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069596.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QXJ2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 219, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QXJ2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXJ2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QXJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2" }, { "id": "PF18517", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18517" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Leucine zipper with capping helix", "eco_id": "ECO_0000259", "start_pos": 165, "end_pos": 218, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QXJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ2" }, { "id": "PF03962", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03962" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mnd1 HTH", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 89, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXJ4-1", "uniprot_ac": "A0A5G2QXJ4", "uniprot_id": "A0A5G2QXJ4_PIG", "mass": { "chemical_mass": 61787.0, "monoisotopic_mass": 61787.0 }, "refseq": {}, "gene_names": [ { "name": "SLC6A20", "type": "recommended", "evidence": [ { "id": "A0A5G2QXJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4" } ] } ], "protein_names": [ { "name": "Transporter", "type": "recommended", "evidence": [ { "id": "A0A5G2QXJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC6A20", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4", "locus": { "chromosome": "13", "start_pos": 28899821, "end_pos": 28945187, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000028643", "url": "https://www.ensembl.org/id/ENSSSCG00000028643" } ] } } ], "crossref": [ { "id": "A0A5G2QXJ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000028643", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000028643", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-352230", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-352230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-442660", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-442660", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R003", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R003", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R003-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R003-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKARPLWDTPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYLIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLGGVGVASVVVSFFLSMYYNVVNAWAFWYLFHSFQDPLPWSVCPLNSNHTGYDEECEKASSTQYFWYRKTLNISPSIQESGPVQWEPALCLILAWLLVYLCILRGTESTGKVEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAVIVSLINSSTSIFASVVTFSIYGFKATFNYESCLKKVILLLTNAFDLEDGFLTASNLEQVKGYLASANPSKYSEVLPQIKNCSLESELETAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKLISSYLPKEAISGLVCLINCAIGMVFTTKAGNYWFDIFNDYAATLSLLLIVLVETIAVCYLYGLRRFENDLKAMMGHTLNWYWKIMWAGVSPLIIISLLLFYLSDYIITGTLQYQAWDASQGQLVTKDYPPYALAIIGLLVAASIMCIPLVALGTFIKHRLKQRATGPMA", "length": 555, "header": "tr|A0A5G2QXJ4-1|A0A5G2QXJ4_PIG Isoform 1 of Transporter OS=Sus scrofa OX=9823 GN=SLC6A20 PE=3 SV=1 CANONICAL=A0A5G2QXJ4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QXJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4/entry#A0A5G2QXJ4-1", "sequence": { "sequence": "MDKARPLWDTPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYLIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLGGVGVASVVVSFFLSMYYNVVNAWAFWYLFHSFQDPLPWSVCPLNSNHTGYDEECEKASSTQYFWYRKTLNISPSIQESGPVQWEPALCLILAWLLVYLCILRGTESTGKVEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAVIVSLINSSTSIFASVVTFSIYGFKATFNYESCLKKVILLLTNAFDLEDGFLTASNLEQVKGYLASANPSKYSEVLPQIKNCSLESELETAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKLISSYLPKEAISGLVCLINCAIGMVFTTKAGNYWFDIFNDYAATLSLLLIVLVETIAVCYLYGLRRFENDLKAMMGHTLNWYWKIMWAGVSPLIIISLLLFYLSDYIITGTLQYQAWDASQGQLVTKDYPPYALAIIGLLVAASIMCIPLVALGTFIKHRLKQRATGPMA", "length": 555, "header": "tr|A0A5G2QXJ4-1|A0A5G2QXJ4_PIG Isoform 1 of Transporter OS=Sus scrofa OX=9823 GN=SLC6A20 PE=3 SV=1 CANONICAL=A0A5G2QXJ4-1" }, "locus": { "chromosome": "13", "start_pos": 28944976, "end_pos": 28903372, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080455.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080455.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062927.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062927.1" } ] } }, { "isoform_ac": "A0A5G2R003-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4/entry#A0A5G2R003-1", "sequence": { "sequence": "MDKARPLWDTPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYLIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLGGVGVASVVVSFFLSMYYNVVNAWAFWYLFHSFQDPLPWSVCPLNSNHTGYDEECEKASSTQYFWYRKTLNISPSIQESGPVQWEPALCLILAWLLVYLCILRGTESTGKVVYFTALLPYCVLIIYLVRGLTLHGATNGLVYMFTPKVEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAVIVSLINSSTSIFASVVTFSIYGFKATFNYESCLKKVILLLTNAFDLEDGFLTASNLEQVKGYLASANPSKYSEVLPQIKNCSLESELETAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKLISSYLPKEAISGLVCLINCAIGMVFTTKAGNYWFDIFNDYAATLSLLLIVLVETIAVCYLYGLRRFENDLKAMMGHTLNWYWKIMWAGVSPLIIISLLLFYLSDYIITGTLQYQAWDASQDAWP", "length": 547, "header": "tr|A0A5G2R003-1|A0A5G2QXJ4_PIG Computationally mapped isoform of Transporter OS=Sus scrofa OX=9823 GN=SLC6A20 PE=3 SV=1 CANONICAL=A0A5G2QXJ4-1" }, "locus": { "chromosome": "13", "start_pos": 28944976, "end_pos": 28902831, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073228.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073228.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070446.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070446.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R003", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R003" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" }, { "id": "R-SSC-442660", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-442660", "resource": "Reactome", "description": "SLC-mediated transport of neurotransmitters" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "L-proline transmembrane transporter activity", "id": "GO:0015193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015193", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4" } ], "pmid": "" }, { "name": "proline:sodium symporter activity", "id": "GO:0005298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005298", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "L-proline import across plasma membrane", "id": "GO:1904271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904271", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4" } ], "pmid": "" }, { "name": "glycine import across plasma membrane", "id": "GO:1903804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903804", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QXJ4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 555, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QXJ4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXJ4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 246, "end_pos": 248 }, { "start_pos": 320, "end_pos": 322 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXJ8-1", "uniprot_ac": "A0A5G2QXJ8", "uniprot_id": "A0A5G2QXJ8_PIG", "mass": { "chemical_mass": 36219.0, "monoisotopic_mass": 36219.0 }, "refseq": { "ac": "XP_003354451", "name": "olfactory receptor 2T29-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354451" }, "gene_names": [ { "name": "LOC100623804", "type": "recommended", "evidence": [ { "id": "A0A5G2QXJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8" } ] }, { "name": "LOC100623804", "type": "synonym", "evidence": [ { "id": "XP_003354451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354451" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QXJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2T29-like", "type": "synonym", "evidence": [ { "id": "XP_003354451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354451" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100623804", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QXJ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXJ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100623804", "url": "https://www.ncbi.nlm.nih.gov/gene/100623804", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623804", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623804", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ITGMATH", "url": "https://omabrowser.org/oma/group/ITGMATH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QXJ8", "url": "https://www.orthodb.org/?gene=A0A5G2QXJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003354451", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354451", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENVNWETNHSGQSGFILVGIFSQSKHPTLLCVVIFIVLLMALIGNTVLIFLIHSDTHLHTAMYFFISQLSLMDVMYISVTVPKMLIDQAMGVNKISAPECAVQMFLYVTLAGSEFFFLAAMAYDRYVAICHPLRYSVLMNHRVCLLLASGCWFLGSVDGFMLTPITMTFPFCRSREIHHFFCEVPAVMKLSCSDTSLYETLMYLCCVLMLLIPVTVISSSYFFILLTIHRMNSAEVRKKAFATCSSHMTVVILFYGAAVYTYMLPNSYHTPEKDMVVSVFYTILTPVLNPLIYSFRNKDVMGALKKMLNVGPVHQETIK", "length": 320, "header": "tr|A0A5G2QXJ8-1|A0A5G2QXJ8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100623804 PE=3 SV=1 CANONICAL=A0A5G2QXJ8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QXJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8/entry#A0A5G2QXJ8-1", "sequence": { "sequence": "MENVNWETNHSGQSGFILVGIFSQSKHPTLLCVVIFIVLLMALIGNTVLIFLIHSDTHLHTAMYFFISQLSLMDVMYISVTVPKMLIDQAMGVNKISAPECAVQMFLYVTLAGSEFFFLAAMAYDRYVAICHPLRYSVLMNHRVCLLLASGCWFLGSVDGFMLTPITMTFPFCRSREIHHFFCEVPAVMKLSCSDTSLYETLMYLCCVLMLLIPVTVISSSYFFILLTIHRMNSAEVRKKAFATCSSHMTVVILFYGAAVYTYMLPNSYHTPEKDMVVSVFYTILTPVLNPLIYSFRNKDVMGALKKMLNVGPVHQETIK", "length": 320, "header": "tr|A0A5G2QXJ8-1|A0A5G2QXJ8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100623804 PE=3 SV=1 CANONICAL=A0A5G2QXJ8-1" }, "locus": { "chromosome": "2", "start_pos": 53251277, "end_pos": 53250318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091455.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091455.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068870.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068870.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623804", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623804", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8NH02-1", "protein_name": "Olfactory receptor 2T29", "gene_name": "OR2T29", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANITRMANHTGRLDFILMGLFRQSKHPALLSVVIFVVFLKALSGNAVLILLIHCDAHLHSPMYFFISQLSLMDMAYISVTVPKMLLDQVMGVNKVSAPECGMQMFLYLTLAGSEFFLLATMAYDRYVAICHPLRYPVLMNHRVCLFLASGCWFLGSVDGFMLTPITMSFPFCRSWEIHHFFCEVPAVTILSCSDTSLYETLMYLCCVLMLLIPVTIISSSYLLILLTVHRMNSAEGRKKAFATCSSHLTVVILFYGAAVYTYMLPSSYHTPEKDMMVSVFYTILTPVLNPLIYSLRNKDVMGALKKMLTVRFVL", "length": 315 }, "evidence": [ { "id": "A0A5G2QXJ8", "url": "https://omabrowser.org/oma/group/A0A5G2QXJ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QXJ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QXJ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXJ8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QXJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 294, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXK2-1", "uniprot_ac": "A0A5G2QXK2", "uniprot_id": "A0A5G2QXK2_PIG", "mass": { "chemical_mass": 34350.0, "monoisotopic_mass": 34350.0 }, "refseq": { "ac": "XP_005660290", "name": "olfactory receptor 13J1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660290" }, "gene_names": [ { "name": "LOC100157239", "type": "recommended", "evidence": [ { "id": "A0A5G2QXK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2" } ] }, { "name": "LOC100157239", "type": "synonym", "evidence": [ { "id": "XP_005660290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660290" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QXK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 13J1-like", "type": "synonym", "evidence": [ { "id": "XP_005660290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660290" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100157239", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2", "locus": {} } ], "crossref": [ { "id": "A0A5G2QXK2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXK2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000051658", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000051658", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15430", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15430", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157239", "url": "https://www.ncbi.nlm.nih.gov/gene/100157239", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157239", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157239", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CMAQLNL", "url": "https://omabrowser.org/oma/group/CMAQLNL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QXK2", "url": "https://www.orthodb.org/?gene=A0A5G2QXK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005660290", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660290", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QXK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELANWTEVSAFFLKGFSGYPALEHLLFPLCSAMYLVTLLGNAAIVAVSVLDAHLHTPMYFFLGNLSILDICFTSSFVPLMLVHLLSVQKTISFIGCAIQMCLGLSTGSTECVLLAVMAYDRYLAICQPLRYPVLMSHRLCLLLAGAAWVLCLLKSVAETIITMRLPFCGHHVVSHFSCEILAVLKLACSDTSVNEGFLLVDAILLLPVPLAFICLSYMLILATILRVPSAAGRKKAFSTCSAHLAVVLLFYGTFILMYLKPKSKDVHVSDKVFTVLYAVVTPMLNPIIYSLRNKEVKEAARKVWGGTWTSR", "length": 312, "header": "tr|A0A5G2QXK2-1|A0A5G2QXK2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100157239 PE=3 SV=1 CANONICAL=A0A5G2QXK2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QXK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2/entry#A0A5G2QXK2-1", "sequence": { "sequence": "MELANWTEVSAFFLKGFSGYPALEHLLFPLCSAMYLVTLLGNAAIVAVSVLDAHLHTPMYFFLGNLSILDICFTSSFVPLMLVHLLSVQKTISFIGCAIQMCLGLSTGSTECVLLAVMAYDRYLAICQPLRYPVLMSHRLCLLLAGAAWVLCLLKSVAETIITMRLPFCGHHVVSHFSCEILAVLKLACSDTSVNEGFLLVDAILLLPVPLAFICLSYMLILATILRVPSAAGRKKAFSTCSAHLAVVLLFYGTFILMYLKPKSKDVHVSDKVFTVLYAVVTPMLNPIIYSLRNKEVKEAARKVWGGTWTSR", "length": 312, "header": "tr|A0A5G2QXK2-1|A0A5G2QXK2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100157239 PE=3 SV=1 CANONICAL=A0A5G2QXK2-1" }, "locus": { "chromosome": "1", "start_pos": 236597257, "end_pos": 236596322, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088425.1", "url": "https://www.ensembl.org/id/ENSSSCT00000088425.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069650.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069650.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157239", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157239", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZIE7-1", "protein_name": "Olfactory receptor", "gene_name": "Or13j1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSNRTAFSEFILKGFSGYPALEHLLFPLCSVMYLVTLLGNTAIVVVSILDARLHTPMYFFLGNLSILDICYTSTFVPLMLVHLLSSRKTISFSGCAIQMCLSLSTGSTECLLLAVMAYDRYLAICQPLRYPVLMSHRLCLMLAGTSWVLCLFKSVTETVIAMRLPFCGRHVIRHFTCEILAVLKLACGDTSVSDAFLLVGAILLLPVPLTLICLSYMLILATILRVPSATGRRKAFSTCSAHLAVVLLFYSTIIFMYMKPKSKEARISDQVFTVLYAVVTPMLNPIIYSLRNKEVKEAARKAWGSRWVCR", "length": 312 }, "evidence": [ { "id": "A0A5G2QXK2", "url": "https://omabrowser.org/oma/group/A0A5G2QXK2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QXK2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QXK2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXK2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QXK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXK2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXL6-1", "uniprot_ac": "A0A5G2QXL6", "uniprot_id": "A0A5G2QXL6_PIG", "mass": { "chemical_mass": 94243.0, "monoisotopic_mass": 94243.0 }, "refseq": { "ac": "XP_020951609", "name": "granulocyte colony-stimulating factor receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020951609" }, "gene_names": [ { "name": "CSF3R", "type": "recommended", "evidence": [ { "id": "A0A5G2QXL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" } ] }, { "name": "CSF3R", "type": "synonym", "evidence": [ { "id": "XP_020951609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020951609" } ] } ], "protein_names": [ { "name": "Granulocyte colony-stimulating factor receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QXL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6/entry#names_and_taxonomy" } ] }, { "name": "granulocyte colony-stimulating factor receptor", "type": "synonym", "evidence": [ { "id": "XP_020951609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020951609" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CSF3R", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6", "locus": { "chromosome": "6", "start_pos": 92550161, "end_pos": 92565477, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000025795", "url": "https://www.ensembl.org/id/ENSSSCG00000025795" } ] } } ], "crossref": [ { "id": "ENSSSCG00000025795", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000025795", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100622336", "url": "https://www.ncbi.nlm.nih.gov/gene/100622336", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100622336", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622336", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYCSIPR", "url": "https://omabrowser.org/oma/group/SYCSIPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QXL6", "url": "https://www.orthodb.org/?gene=A0A5G2QXL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48423", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48423", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48423:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48423:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06328", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06328", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-449836", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-449836", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9674555", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9674555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9705462", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9705462", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020951609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020951609", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QXL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LQQ8", "url": "https://www.uniprot.org/uniprotkb/I3LQQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LQQ8-1", "url": "https://www.uniprot.org/uniprotkb/I3LQQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAGLGAWSLAGAVLIILLLPRSLEECGYISLPAPIIRLGDPITVSCIINQNCTSLGPESQIRWKLDTELQPGGRQQHLPNGTLQSTITFPHFNYSRALLSCCLHWGNGLQILDQAELQAGYPPPPPYNLSCLLNLTTNSLKCQWEPGPDTHLSTHFTLKSFKSRGNFQTQEDSIPDCVPEDGQNHCSIPRKHLQLYQNMSIWVQAKNALGTSTSPKLCLVPMDMVKLEPPTLWALEPSPEVAPPQPGCLRLRWETWKPSLHIEQKCELRHQPQRGESSWDLVGALPSRSLQYELCGLLPSTAYTLQMRCTRWPLPGRWSDWSPRLELTTAQQPPIVRLDTWWRQRQLDPRTVDVQLFWKPMPLQEDSGQIQGYLVSWRPSDQAEADPILCNTTELNCTFQLPSEAREVVLVAYNAAGTSRPTPVVFLESRGPPLRRLRTTARDPHSLWVGWEPPSPRPRGYVIEWGLGTPSPGGNPMTWRMEHNGSIAGTLLQENIKPFQLYKITVTALYQDAKGPSQHIYAYSQEMAPSHGPELHLRHIGKTWAQLEWVPEAPELGKSPLTHYTIFWTNAQDQSFSTVLNASSHGFVLRGLEPASLYHVHLMAVSQAWTTNSTSLTLMTLALEESELHILLGLFGLLVLFFCLCGAAQLCCRPRKNPLWPSVPDPAHSSLGSWVPTITAEDTFQLPSLRDPGMPPITKITVLEEEEKKPGPWESKSGPWESNDSSGTCSHPTLVQAYVLQGDPRVPATQAQPQSSTSDQVLYVQVLGSPTSPGPGHYLRCDSTQPLLGGLTPSPKSYENLWFQTSPLGTPEPLVPNPEDDCIFEPLLDFPLLQGLRVSGAEGLGGF", "length": 848, "header": "tr|A0A5G2QXL6-1|A0A5G2QXL6_PIG Isoform 1 of Granulocyte colony-stimulating factor receptor OS=Sus scrofa OX=9823 GN=CSF3R PE=3 SV=1 CANONICAL=A0A5G2QXL6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QXL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6/entry#A0A5G2QXL6-1", "sequence": { "sequence": "MVAGLGAWSLAGAVLIILLLPRSLEECGYISLPAPIIRLGDPITVSCIINQNCTSLGPESQIRWKLDTELQPGGRQQHLPNGTLQSTITFPHFNYSRALLSCCLHWGNGLQILDQAELQAGYPPPPPYNLSCLLNLTTNSLKCQWEPGPDTHLSTHFTLKSFKSRGNFQTQEDSIPDCVPEDGQNHCSIPRKHLQLYQNMSIWVQAKNALGTSTSPKLCLVPMDMVKLEPPTLWALEPSPEVAPPQPGCLRLRWETWKPSLHIEQKCELRHQPQRGESSWDLVGALPSRSLQYELCGLLPSTAYTLQMRCTRWPLPGRWSDWSPRLELTTAQQPPIVRLDTWWRQRQLDPRTVDVQLFWKPMPLQEDSGQIQGYLVSWRPSDQAEADPILCNTTELNCTFQLPSEAREVVLVAYNAAGTSRPTPVVFLESRGPPLRRLRTTARDPHSLWVGWEPPSPRPRGYVIEWGLGTPSPGGNPMTWRMEHNGSIAGTLLQENIKPFQLYKITVTALYQDAKGPSQHIYAYSQEMAPSHGPELHLRHIGKTWAQLEWVPEAPELGKSPLTHYTIFWTNAQDQSFSTVLNASSHGFVLRGLEPASLYHVHLMAVSQAWTTNSTSLTLMTLALEESELHILLGLFGLLVLFFCLCGAAQLCCRPRKNPLWPSVPDPAHSSLGSWVPTITAEDTFQLPSLRDPGMPPITKITVLEEEEKKPGPWESKSGPWESNDSSGTCSHPTLVQAYVLQGDPRVPATQAQPQSSTSDQVLYVQVLGSPTSPGPGHYLRCDSTQPLLGGLTPSPKSYENLWFQTSPLGTPEPLVPNPEDDCIFEPLLDFPLLQGLRVSGAEGLGGF", "length": 848, "header": "tr|A0A5G2QXL6-1|A0A5G2QXL6_PIG Isoform 1 of Granulocyte colony-stimulating factor receptor OS=Sus scrofa OX=9823 GN=CSF3R PE=3 SV=1 CANONICAL=A0A5G2QXL6-1" }, "locus": { "chromosome": "6", "start_pos": 92562270, "end_pos": 92550435, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080717.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080717.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066684.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066684.1" } ] } }, { "isoform_ac": "I3LQQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6/entry#I3LQQ8-1", "sequence": { "sequence": "MVAGLGAWSLAGAVLIILLLPRSLEECGYISLPAPIIRLGDPITVSCIINQNCTSLGPESQIRWKLDTELQPGGRQQHLPNGTLQSTITFPHFNYSRALLSCCLHWGNGLQILDQAELQAGYPPPPPYNLSCLLNLTTNSLKCQWEPGPDTHLSTHFTLKSFKSRGNFQTQEDSIPDCVPEDGQNHCSIPRKHLQLYQNMSIWVQAKNALGTSTSPKLCLVPMDMVKLEPPTLWALEPSPEVAPPQPGCLRLRWETWKPSLHIEQKCELRHQPQRGESSWDLVGALPSRSLQYELCGLLPSTAYTLQMRCTRWPLPGRWSDWSPRLELTTAQQPPIVRLDTWWRQRQLDPRTVDVQLFWKPMPLQEDSGQIQGYLVSWRPSDQAEADPILCNTTELNCTFQLPSEAREVVLVAYNAAGTSRPTPVVFLESRGPPLRRLRTTARDPHSLWVGWEPPSPRPRGYVIEWGLGTPSPGGNPMTWRMEHNGSIAGTLLQENIKPFQLYKITVTALYQDAKGPSQHIYAYSQEMAPSHGPELHLRHIGKTWAQLEWVPEAPELGKSPLTHYTIFWTNAQDQSFSTVLNASSHGFVLRGLEPASLYHVHLMAVSQAWTTNSTSLTLMTLALGRIPSGQVFQTQPTAVWVPGCQPSQQKIPSSCPAFGTLACHPSPRSQCWKRKRRSQGPGSPSQGPGSPMTAQGPAATPLWSRPMCSRGTQEYLPPRPSPSPAPVTRSFMCRCWAAPRAQGLGTTSAATPLSPSWGASPPAPSPMRTSGSRQAPWGPQNP", "length": 783, "header": "tr|I3LQQ8-1|A0A5G2QXL6_PIG Computationally mapped isoform of Granulocyte colony-stimulating factor receptor OS=Sus scrofa OX=9823 GN=CSF3R PE=3 SV=3 CANONICAL=A0A5G2QXL6-1" }, "locus": { "chromosome": "6", "start_pos": 92562270, "end_pos": 92550536, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026465.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026465.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026438.3", "url": "https://www.ensembl.org/id/ENSSSCP00000026438.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LQQ8", "url": "https://www.uniprot.org/uniprotkb/I3LQQ8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100622336", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622336", "resource": "KEGG Pathway" }, { "id": "R-SSC-449836", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-449836", "resource": "Reactome", "description": "Other interleukin signaling" }, { "id": "R-SSC-9674555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9674555", "resource": "Reactome", "description": "Signaling by CSF3 (G-CSF)" }, { "id": "R-SSC-9705462", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9705462", "resource": "Reactome", "description": "Inactivation of CSF3 (G-CSF) signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LU43-1", "protein_name": "Granulocyte colony-stimulating factor receptor", "gene_name": "CSF3R", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVGLGAWSLVGAALIILLLPRSLEQCGHILLSAPIVRLGDQVTASCIINRNCSHLGTDWRVVWKLEPELHPRERRQHLPNGTLQSTITLPHLNHSRVLLSCCLHWGNSLQILDQAELQAGYPPTAPYNLSCIMNLTTNSLICQWEPGPNTHLSTSFTLKSFKSQDKCQTQKDSIPDCVPEVGQSHCSIPRKHLQLYQNMSIWVQARNALGTSASPKLCLAPMDVVKLEPPTLWALEPSPAVAPPQPGCLRLRWETWRPSLYIEQKCELRHQPRLGEAGWDLVSALPARTSQYELCGLLPSTAYTLQMRCTRWRLPGHWSEWSPSLELTTAQRAPIVRLDTWWRQRQLDPETVTVQLFWKPIALEEDSGQIQGYLVSWRPSDQAGAEPTLCDTTELNCTFQLPSEAREVVLKAYNTAGTSHPTPVVFLESRGPPLGRLHTTARDPHSLWVGWEPPSPQPQGYVIEWGLSPPSPNGSPMTWRMEHNGSIAGTLLQENIRPFQLYEITVTPLYQDTKGPSQHIYAYSQEMAPSHGPELHLRHIGKTWAQLEWVPEAPELGKSPLTHYTIFWTNTQDQSFSTVLNASTHSFVLRGLEPSSLYHVQLMAASQVWAANSTSLTLMTLTLEESELHILLGLFGLLVLLICLCGAAQFCCRPSRKYSLWPSVPDPARSSLGSWVPTITAEDILQLPSLRDPGMPPITKITVLEEEEKKPGPWESNASSGPGSLSTLVQAYVLQGDPRVPSAQPQPQPGNSDQVLYVQVLGSPTGPGPGHYLRCDSTQPLLEGLSPSPKSYENLWFQTSSPGTPEPLVPHPEDDSIFEPLLDFPLLQGLRVSGAEGLGGF", "length": 841 }, "evidence": [ { "id": "A0A5G2QXL6", "url": "https://omabrowser.org/oma/group/A0A5G2QXL6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I6B3M3-1", "protein_name": "Colony stimulating factor 3 receptor", "gene_name": "Csf3r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVGLGACNLTGVTLIVLLLPRSLEGCGQIRISPPIVHLGDPVLASCTISPNCSKLDRQPKILWRLQDEPNQPGDRQHHLPDGSQESIITLPHLNYTQAFLFCLVPWNNSFQVLDQAELRAGYPPASPSNLSCLMYLTTNSLVCQWEPGPETHLPTSFILKSFRSRTGCQYQGGTILDCMPKKRHSNCSIPRKHLLLYQNMVIWVQAENMLGSSESPKLCIDPMDVGRESLTTPPPAVKLEPPMLQALDIGHDIVSRQPGCLWLSWKPWKPSEFMEQECELRYQPQLEGANWTLVRPRKTSRWRWGMERGQAGFSVTPPTHQVSHLPSSTDRFELCSLHQAPVYTLQLRCIRSSLPGLWSSWSPGLQLRPTIKAPTIRLDTWWQKKHLDPETVRMQLFWKPTPLQKDSGQIQGYLLSWSCPDGQGRIMHLCNTTELSCTFHLPSEAQNVTLVAYNSAGTSSPTLVVFLEHEGPAVTSLHAMAQDLGSIWVDWEAPSLLPQGYLIEWGPDSHKYSNNSWRIEPNGNTTGILLEDNIHPFQLYRITVAPLYPGTVGPPVNVYTYSGEKALPHAPELYLKHVGRTWAQLEWVPETPWLGMIPLTNYTIFWTDARDHSFSVTLNISFHDFVLDHLKPASLYHVYLMATSRAGSTNSTGLTLMTMALDSSDVNIFLGILCFVLLSITCATAWFCCKQSRKTFFWPNVPDPAHSSLSAWVPTIMTEETFQLPSFWGSSVPSITKITELEEDKKPTHWDPSESSGTGSLPAVVQAYVLQGDPREISNQFQPPSSTNDQVLYGQVLGSPTSPEVVGYLRCDSTQPLLGGPTPSPKSYENIWFHSRPQETFIPQPPSQEDDCVFGPPFDFPLFQGLQVHGVEEQGGF", "length": 877 }, "evidence": [ { "id": "A0A5G2QXL6", "url": "https://omabrowser.org/oma/group/A0A5G2QXL6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YPI5-1", "protein_name": "Colony stimulating factor 3 receptor", "gene_name": "CSF3R", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARRGAGSPLLLQLSLLLLLSPSGTQQSGAELDCASVAVGAPVVPMGSAVTASCTIRRERCRGLEDGQPLISWLLDSEPMAGRQRRGVGGTEVSELRVPQLNRPQAKLWCCVEWNGTKQRVGVAEIRAGYPPGKPSNLSCLLDLGDYGLTCRWQQGADGHLPTNIMLKCATSRSPAVTGCTPQNGHSQCTVPRRLLQLYRPMELWVTATNALGTAESERLRIDPMDVAKLDPPTLQSIRSMPPQTDCVTLTWTMTPRNAHMELRCELRYRAPEDPSWGVLTGIAGHAGTVQHCKFLFGTLYHFQMRCRRDLARGYWSEWSVSRNYTTHEKAPEGKLDAWWSTRTAAGRMEVQLRWKAPRRQEANGRVLGYRVALGSRRRGREPQTVCNTNDTHCDFTVPVRTGRVYLSAYNAAGESSATEVILLERKGQPLAGLRAVPAGDRSLWVHWEAAPVPVVAYVLEWQPVSSEPRHCSACWQLERNGTTTTTLIRDSIEPFQQYNISVYPLYKDAVGTPAYIAAYSKQKAPSHAPKLHLKSIGKSQAKLSWEPVAVELQNGFITHYTVFWANSTAEVSSAVVNSSLSSFTIQGLKPSTLYKVHIMASTAGGSINGTTLTLVTTMLDDTEIQFLFLTLGLVFVLLIILLICFQKNGRVKQQFWPSVPDPANSSLGTWVPAEQEPLQAPGVKEPGLATISTVTVLDKAAGKQTPTWGKEPPAEPLAPPQPYMQQHRPGTLQANSGLAAEPVQYVQVVGGSSQGPQHVAPCLYLRSSSTQPLLSDPSPEPYENLWFRGAAPSCARGSLEEPLLDFPLLRGLRVSGAEELHDFQPC", "length": 827 }, "evidence": [ { "id": "A0A5G2QXL6", "url": "https://omabrowser.org/oma/group/A0A5G2QXL6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P40223-1", "protein_name": "Granulocyte colony-stimulating factor receptor", "gene_name": "Csf3r", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGLGACTLTGVTLIFLLLPRSLESCGHIEISPPVVRLGDPVLASCTISPNCSKLDQQAKILWRLQDEPIQPGDRQHHLPDGTQESLITLPHLNYTQAFLFCLVPWEDSVQLLDQAELHAGYPPASPSNLSCLMHLTTNSLVCQWEPGPETHLPTSFILKSFRSRADCQYQGDTIPDCVAKKRQNNCSIPRKNLLLYQYMAIWVQAENMLGSSESPKLCLDPMDVVKLEPPMLQALDIGPDVVSHQPGCLWLSWKPWKPSEYMEQECELRYQPQLKGANWTLVFHLPSSKDQFELCGLHQAPVYTLQMRCIRSSLPGFWSPWSPGLQLRPTMKAPTIRLDTWCQKKQLDPGTVSVQLFWKPTPLQEDSGQIQGYLLSWSSPDHQGQDIHLCNTTQLSCIFLLPSEAQNVTLVAYNKAGTSSPTTVVFLENEGPAVTGLHAMAQDLNTIWVDWEAPSLLPQGYLIEWEMSSPSYNNSYKSWMIEPNGNITGILLKDNINPFQLYRITVAPLYPGIVGPPVNVYTFAGERAPPHAPALHLKHVGTTWAQLEWVPEAPRLGMIPLTHYTIFWADAGDHSFSVTLNISLHDFVLKHLEPASLYHVYLMATSRAGSTNSTGLTLRTLDPSDLNIFLGILCLVLLSTTCVVTWLCCKRRGKTSFWSDVPDPAHSSLSSWLPTIMTEETFQLPSFWDSSVPSITKITELEEDKKPTHWDSESSGNGSLPALVQAYVLQGDPREISNQSQPPSRTGDQVLYGQVLESPTSPGVMQYIRSDSTQPLLGGPTPSPKSYENIWFHSRPQETFVPQPPNQEDDCVFGPPFDFPLFQGLQVHGVEEQGGF", "length": 837 }, "evidence": [ { "id": "A0A5G2QXL6", "url": "https://omabrowser.org/oma/group/A0A5G2QXL6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99062-1", "protein_name": "Granulocyte colony-stimulating factor receptor", "gene_name": "CSF3R", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARLGNCSLTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRLGAELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPKDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDPRTVQLFWKPVPLEEDSGRIQGYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSRPTPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEWGLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSFSAILNASSRGFVLHGLEPASLYHIHLMAASQAGATNSTVLTLMTLTPEGSELHIILGLFGLLLLLTCLCGTAWLCCSPNRKNPLWPSVPDPAHSSLGSWVPTIMEEDAFQLPGLGTPPITKLTVLEEDEKKPVPWESHNSSETCGLPTLVQTYVLQGDPRAVSTQPQSQSGTSDQVLYGQLLGSPTSPGPGHYLRCDSTQPLLAGLTPSPKSYENLWFQASPLGTLVTPAPSQEDDCVFGPLLNFPLLQGIRVHGMEALGSF", "length": 836 }, "evidence": [ { "id": "A0A5G2QXL6", "url": "https://omabrowser.org/oma/group/A0A5G2QXL6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" } ], "pmid": "" }, { "name": "endocytic vesicle membrane", "id": "GO:0030666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030666", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" } ], "pmid": "" }, { "name": "granulocyte colony-stimulating factor binding", "id": "GO:0051916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051916", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 613, "end_pos": 615, "annotation": "n_glycosylation_sequon" }, { "start_pos": 724, "end_pos": 726, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QXL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL6" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 126, "end_pos": 231, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 135, "end_pos": 137 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 485, "end_pos": 487 }, { "start_pos": 52, "end_pos": 54 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 613, "end_pos": 615 }, { "start_pos": 724, "end_pos": 726 }, { "start_pos": 81, "end_pos": 83 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXL9-1", "uniprot_ac": "A0A5G2QXL9", "uniprot_id": "A0A5G2QXL9_PIG", "mass": { "chemical_mass": 35501.0, "monoisotopic_mass": 35501.0 }, "refseq": { "ac": "XP_003129484", "name": "olfactory receptor 56A3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129484" }, "gene_names": [ { "name": "LOC110255251", "type": "synonym", "evidence": [ { "id": "XP_003129484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129484" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 56A3-like", "type": "synonym", "evidence": [ { "id": "XP_003129484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129484" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9", "locus": {} } ], "crossref": [ { "id": "A0A5G2QXL9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "110255251", "url": "https://www.ncbi.nlm.nih.gov/gene/110255251", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110255251", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255251", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DVTINCH", "url": "https://omabrowser.org/oma/group/DVTINCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QXL9", "url": "https://www.orthodb.org/?gene=A0A5G2QXL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003129484", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129484", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QXL9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAHQNGTIATEVSHFLLNCFVRSPSWQLWLSLPLSLLLLLALGANTTLLVTIRLEASLHQPMYYLLSLLSLLDMVLCLTVIPKVLAIFWFDLRAISFSACFLQMFIMNCFFAMESCTFMVMAYDRYVAICHPLRYPSIITDQFVAKAAIFILARNFILTLPIPILSSRLHYCGRNVIENCLCANMSVSRLSYDDITINRLYQFALSWTMLGSDLILIFASYTLILRAVLRLKAEGAVAKALGTCGSHFILILFFSTILLVFVLTHVAKKKVPPDVPVLLNVLHHVVPAALNPIVYGVRTQEIKQGIQRLLKKGW", "length": 315, "header": "tr|A0A5G2QXL9-1|A0A5G2QXL9_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QXL9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QXL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9/entry#A0A5G2QXL9-1", "sequence": { "sequence": "MTAHQNGTIATEVSHFLLNCFVRSPSWQLWLSLPLSLLLLLALGANTTLLVTIRLEASLHQPMYYLLSLLSLLDMVLCLTVIPKVLAIFWFDLRAISFSACFLQMFIMNCFFAMESCTFMVMAYDRYVAICHPLRYPSIITDQFVAKAAIFILARNFILTLPIPILSSRLHYCGRNVIENCLCANMSVSRLSYDDITINRLYQFALSWTMLGSDLILIFASYTLILRAVLRLKAEGAVAKALGTCGSHFILILFFSTILLVFVLTHVAKKKVPPDVPVLLNVLHHVVPAALNPIVYGVRTQEIKQGIQRLLKKGW", "length": 315, "header": "tr|A0A5G2QXL9-1|A0A5G2QXL9_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QXL9-1" }, "locus": { "chromosome": "9", "start_pos": 3550117, "end_pos": 3549173, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072783.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072783.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069670.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069670.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110255251", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255251", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXL9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QXL9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 315, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QXL9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXL9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXL9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 296, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 }, { "start_pos": 46, "end_pos": 48 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXW0-1", "uniprot_ac": "A0A5G2QXW0", "uniprot_id": "A0A5G2QXW0_PIG", "mass": { "chemical_mass": 201866.0, "monoisotopic_mass": 201866.0 }, "refseq": { "ac": "XP_003484029", "name": "brefeldin A-inhibited guanine nucleotide-exchange protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003484029" }, "gene_names": [ { "name": "ARFGEF2", "type": "recommended", "evidence": [ { "id": "A0A5G2QXW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ] }, { "name": "ARFGEF2", "type": "synonym", "evidence": [ { "id": "XP_003484029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003484029" } ] } ], "protein_names": [ { "name": "ADP ribosylation factor guanine nucleotide exchange factor 2", "type": "synonym", "evidence": [ { "id": "A0A5G2QXW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0/entry#names_and_taxonomy" } ] }, { "name": "brefeldin A-inhibited guanine nucleotide-exchange protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003484029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003484029" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARFGEF2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0", "locus": { "chromosome": "17", "start_pos": 50732243, "end_pos": 50631092, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007460", "url": "https://www.ensembl.org/id/ENSSSCG00000007460" } ] } } ], "crossref": [ { "id": "ENSSSCG00000007460", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007460", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523757", "url": "https://www.ncbi.nlm.nih.gov/gene/100523757", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523757", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523757", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FWKSNEM", "url": "https://omabrowser.org/oma/group/FWKSNEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QXW0", "url": "https://www.orthodb.org/?gene=A0A5G2QXW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF124", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF124", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01369", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01369", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12783", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12783", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16213", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16213", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20252", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20252", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003484029", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003484029", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F657", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F657", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F657-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F657-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGK8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SBE8", "url": "https://www.uniprot.org/uniprotkb/F1SBE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SBE8-1", "url": "https://www.uniprot.org/uniprotkb/F1SBE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQESQTKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAEIEKQRLGAAAPPKANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETICNCFQGPQTDEGVQLQIIKALLTAVTSPHIEIHEGTVLQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTRMENQVLQEARELEKPVHSKPQSPVIQAAAVSPKFSRLKQSQAQSKPTTPEKTELTNGEHARSGSGKVSVENGDALRERGPSLSGTEDGAQEVVKEILEDVVTSAVKEAAQKHGLTEPERVLGELESQERAVPPAADENPQTNGVADDRQSLSSADNLESDAQGHPVAARFSHILQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRTHEMFINAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGHELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQTSLGQERPTDQEMGDGKGLDLARRSSVTSMESTVSSGTQTAVQDDPEQFEVIKQQKEMIEHGIELFNKKPKRGIQYLQEQGMLGTSVEDIAQFLHQEDRLDSTQVGDFLGESMKFNKEVMYAYVDQLDFCDKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKKIAMKETKEHTIATKSTKQSVASEKQRRLLYNLEMEQMAKTAKALMEAVSHAKAPFTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREGSLKGHTLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELASPHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCLAQMVNSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVTTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYTSDDMNVAPGDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWQDLFRIVFRIFDNMKLPEQQSEKSEWMTTTCNHALYAVCDVFTQFYEALNEVLLSDIFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAVWDETCNCMLDIFKTTIPHILLTWRPVGMEEDPSEKHLDVDLDRQSLSSIDKNASERGQSQLSNPTDDSWKARPYANQKLFASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHLVAAQQDTLDADIHIETEDQGMYKCMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWEEIQQRLLTVCSEALAYFITVNSESHREAWTSLLLLLLTKTLKINDEKFKAHASMYYPYLCEIMQFDLIPELRAVLRKFFLRIGVVYKIWIPEEPSQVPGTLSPIW", "length": 1785, "header": "tr|A0A5G2QXW0-1|A0A5G2QXW0_PIG Isoform 1 of ADP ribosylation factor guanine nucleotide exchange factor 2 OS=Sus scrofa OX=9823 GN=ARFGEF2 PE=1 SV=1 CANONICAL=A0A5G2QXW0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QXW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0/entry#A0A5G2QXW0-1", "sequence": { "sequence": "MQESQTKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAEIEKQRLGAAAPPKANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETICNCFQGPQTDEGVQLQIIKALLTAVTSPHIEIHEGTVLQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTRMENQVLQEARELEKPVHSKPQSPVIQAAAVSPKFSRLKQSQAQSKPTTPEKTELTNGEHARSGSGKVSVENGDALRERGPSLSGTEDGAQEVVKEILEDVVTSAVKEAAQKHGLTEPERVLGELESQERAVPPAADENPQTNGVADDRQSLSSADNLESDAQGHPVAARFSHILQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRTHEMFINAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGHELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQTSLGQERPTDQEMGDGKGLDLARRSSVTSMESTVSSGTQTAVQDDPEQFEVIKQQKEMIEHGIELFNKKPKRGIQYLQEQGMLGTSVEDIAQFLHQEDRLDSTQVGDFLGESMKFNKEVMYAYVDQLDFCDKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKKIAMKETKEHTIATKSTKQSVASEKQRRLLYNLEMEQMAKTAKALMEAVSHAKAPFTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREGSLKGHTLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELASPHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCLAQMVNSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVTTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYTSDDMNVAPGDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWQDLFRIVFRIFDNMKLPEQQSEKSEWMTTTCNHALYAVCDVFTQFYEALNEVLLSDIFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAVWDETCNCMLDIFKTTIPHILLTWRPVGMEEDPSEKHLDVDLDRQSLSSIDKNASERGQSQLSNPTDDSWKARPYANQKLFASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHLVAAQQDTLDADIHIETEDQGMYKCMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWEEIQQRLLTVCSEALAYFITVNSESHREAWTSLLLLLLTKTLKINDEKFKAHASMYYPYLCEIMQFDLIPELRAVLRKFFLRIGVVYKIWIPEEPSQVPGTLSPIW", "length": 1785, "header": "tr|A0A5G2QXW0-1|A0A5G2QXW0_PIG Isoform 1 of ADP ribosylation factor guanine nucleotide exchange factor 2 OS=Sus scrofa OX=9823 GN=ARFGEF2 PE=1 SV=1 CANONICAL=A0A5G2QXW0-1" }, "locus": { "chromosome": "17", "start_pos": 50728747, "end_pos": 50632031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066737.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066737.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063042.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063042.1" } ] } }, { "isoform_ac": "A0A5G2R1X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0/entry#A0A5G2R1X7-1", "sequence": { "sequence": "MAYGGPRTKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKVAVREPRSLTANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETICNCFQGPQTDEGVQLQIIKALLTAVTSPHIEIHEGTVLQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTRMENQVLQEARELEKPVHSKPQSPVIQAAAVSPKFSRLKQSQAQSKPTTPEKTELTNGEHARSGSGKVSVENGDALRERGPSLSGTTHESDAQGHPVAARFSHILQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRTHEMFINAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGHELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQTSLGQERPTDQEMGDGKGLDLARRSSVTSMESTVSSGTQTAVQDDPEQFEVIKQQKEMIEHGIELFNKKPKRGIQYLQEQGMLGTSVEDIAQFLHQEDRLDSTQVGDFLGESMKFNKEVMYAYVDQLDFCDKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKKIAMKETKEHTIATKSTKQSVASEKQRRLLYNLEMEQMAKTAKALMEAVSHAKAPFTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREGSLKGHTLAGEEFMGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELASPHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCLAQMVNSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVTTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYTSDDMNVAPGDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWQDLFRIVFRIFDNMKLPEQQSEKSEWMTTTCNHALYAVCDVFTQFYEALNEVLLSDIFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAVWDETCNCMLDIFKTTIPHILLTWRPVGMEEDPSEKHLITHSHDSDVQKGKQDINQKLFASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHLVAAQQDTLDADIHIETEDQGMYKCMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWEEIQQRLLTVCSEALAYFITVNSESHREAWTSLLLLLLTKTLKINDEKFKAHASMYYPYLCEIMQFDLIPELRAVLRKFFLRIGVVYKIWIPEEPSQSVGKRKQLNEDDY", "length": 1692, "header": "tr|A0A5G2R1X7-1|A0A5G2QXW0_PIG Computationally mapped isoform of ADP ribosylation factor guanine nucleotide exchange factor 2 OS=Sus scrofa OX=9823 GN=ARFGEF2 PE=1 SV=1 CANONICAL=A0A5G2QXW0-1" }, "locus": { "chromosome": "17", "start_pos": 50729527, "end_pos": 50631092, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067659.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067659.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071114.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071114.1" } ] } }, { "isoform_ac": "A0A8W4F657-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0/entry#A0A8W4F657-1", "sequence": { "sequence": "TKSMFVSRALEKILADKEVKRPQHSQLRRACQVALVDLKVAVREPRSLTANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETICNCFQGPQTDEGVQLQIIKALLTAVTSPHIEIHEGTVLQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTRMENQVLQEARELEKPVHSKPQSPVIQAAAVSPKFSRLKQSQAQSKPTTPEKTELTNGEHARSGSGKVSVENGDALRERGPSLSGTTHESDAQGHPVAARFSHILQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRTHEMFINAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGHELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQTSLGQERPTDQEMGDGKGLDLARRSSVTSMESTVSSGTQTAVQDDPEQFEVIKQQKEMIEHGIELFNKKPKRGIQYLQEQGMLGTSVEDIAQFLHQEDRLDSTQVGDFLGESMKFNKEVMYAYVDQLDFCDKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKKIAMKETKEHTIATKSTKQSVASEKQRRLLYNLEMEQMAKTAKALMEAVSHAKAPFTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREGSLKGHTLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELASPHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCLAQMVNSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVTTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYTSDDMNVAPGDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWQDLFRIVFRIFDNMKLPEQQSEKSEWMTTTCNHALYAVCDVFTQFYEALNEVLLSDIFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAVWDETCNCMLDIFKTTIPHILLTWRPVGMEEDPSEKHLITHSHDSDVQKGKQDISLSFTPGPHLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHLVAAQQDTLDADIHIETEDQGMYKCMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWEEIQQRLLTVCSEALAYFITVNSESHREAWTSLLLLLLTKTLKINDEKFKAHASMYYPYLCEIMQFDLIPELRAVLRKFFLRIGVVYKIWIPEEPSQSVGKRKQLNEDDY", "length": 1689, "header": "tr|A0A8W4F657-1|A0A5G2QXW0_PIG Computationally mapped isoform of ADP ribosylation factor guanine nucleotide exchange factor 2 OS=Sus scrofa OX=9823 GN=ARFGEF2 PE=1 SV=1 CANONICAL=A0A5G2QXW0-1" }, "locus": { "chromosome": "17", "start_pos": 50729527, "end_pos": 50632046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095328.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095328.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074631.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074631.1" } ] } }, { "isoform_ac": "A0A8W4FGK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0/entry#A0A8W4FGK8-1", "sequence": { "sequence": "MAYGGPRTKSMFVSRALEKILADKEVKRPQHSQLRRACQVALGAAAPPKANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETICNCFQGPQTDEGVQLQIIKALLTAVTSPHIEIHEGTVLQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTRMENQVLQEARELEKPVHSKPQSPVIQAAAVSPKFSRLKQSQAQSKPTTPEKTELTNGEHARSGSGKVSVENGDALRERGPSLSGTTHESDAQGHPVAARFSHILQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRTHEMFINAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGHELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQTSLGQERPTDQEMGDGKGLDLARRSSVTSMESTVSSGTQTAVQDDPEQFEVIKQQKEMIEHGIELFNKKPKRGIQYLQEQGMLGTSVEDIAQFLHQEDRLDSTQVGDFLGESMKFNKEVMYAYVDQLDFCDKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKKIAMKETKEHTIATKSTKQSVASEKQRRLLYNLEMEQMAKTAKALMEAVSHAKAPFTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREGSLKGHTLAGEEFMGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELASPHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCLAQMVNSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVTTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYTSDDMNVAPGDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWQDLFRIVFRIFDNMKLPEQQSEKSEWMTTTCNHALYAVCDVFTQFYEALNEVLLSDIFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAVWDETCNCMLDIFKTTIPHILLTWRPVGMEEDPSEKHLITHSHDSDVQKGKQDINQKLFASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHLVAAQQDTLDADIHIETEDQGMYKCMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWEEIQQRLLTVCSEALAYFITVNSESHREAWTSLLLLLLTKTLKINDEKFKAHASMYYPYLCEIMQFDLIPELRAVLRKFFLRIGVVYKIWIPEEPSQSVGKRKQLNEDDY", "length": 1685, "header": "tr|A0A8W4FGK8-1|A0A5G2QXW0_PIG Computationally mapped isoform of ADP ribosylation factor guanine nucleotide exchange factor 2 OS=Sus scrofa OX=9823 GN=ARFGEF2 PE=1 SV=1 CANONICAL=A0A5G2QXW0-1" }, "locus": { "chromosome": "17", "start_pos": 50729527, "end_pos": 50631092, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097664.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097664.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078452.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078452.1" } ] } }, { "isoform_ac": "F1SBE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0/entry#F1SBE8-1", "sequence": { "sequence": "MLNVIFTRMENQVLQEARELEKPVHSKPQSPVIQAAAVSPKFSRLKQSQAQSKPTTPEKTELTNGEHARSGSGKVSVENGDALRERGPSLSGTEDGAQEVVKEILEDVVTSAVKEAAQKHGLTEPERVLGELESQERAVPPAADENPQTNGVADDRQSLSSADNLESDAQGHPVAARFSHILQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRTHEMFINAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGHELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQTSLGQERPTDQEMGDGKGLDLARRSSVTSMESTVSSGTQTAVQDDPEQFEVIKQQKEMIEHGIELFNKKPKRGIQYLQEQGMLGTSVEDIAQFLHQEDRLDSTQVGDFLGESMKFNKEVMYAYVDQLDFCDKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKKIAMKETKEHTIATKSTKQSVASEKQRRLLYNLEMEQMAKTAKALMEAVSHAKAPFTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREGSLKGHTLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELASPHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCLAQMVNSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVTTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYTSDDMNVAPGDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWQDLFRIVFRIFDNMKLPEQQSEKSEWMTTTCNHALYAVCDVFTQFYEALNEVLLSDIFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAVWDETCNCMLDIFKTTIPHILLTWRPVGMEEDPSEKHLDVDLDRQSLSSIDKNASERGQSQLSNPTDDSWKARPYANQKLFASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHLVAAQQDTLDADIHIETEDQGMYKCMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWEEIQQRLLTVCSEALAYFITVNSESHREAWTSLLLLLLTKTLKINDEKFKAHASMYYPYLCEIMQFDLIPELRAVLRKFFLRIGVVYKIWIPEEPSQVPGTLSPIW", "length": 1597, "header": "tr|F1SBE8-1|A0A5G2QXW0_PIG Computationally mapped isoform of ADP ribosylation factor guanine nucleotide exchange factor 2 OS=Sus scrofa OX=9823 GN=ARFGEF2 PE=1 SV=3 CANONICAL=A0A5G2QXW0-1" }, "locus": { "chromosome": "17", "start_pos": 50728747, "end_pos": 50657081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008164.5", "url": "https://www.ensembl.org/id/ENSSSCT00000008164.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007948.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007948.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1X7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1X7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523757", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523757", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2A5R2-1", "protein_name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 2", "gene_name": "Arfgef2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQESQTKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAELEKQRLGAAAPPKANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETICNCFQGPQTDEGVQLQIIKALLTAVTSPHIEIHEGTILQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTRMENQVLQEARELEKPMQSKPQSPVIQATAGSPKFSRLKQSQAQSKPTTPEKAELPNGDHAQSGLGKVSLENGEAPRERGSPVSGRAEPSRGTDSGAQEVVKDILEDVVTSAVKEAAEKHGLPEPDRALGALECQECAVPPGVDENSQTNGIADDRQSLSSADNLEPDVQGHQVAARFSHILQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRSHEMFVTAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGHELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQATLGQERLPDQEMGDGKGLDMARRCSVTSVESTVSSGTQTAIQDDPEQFEVIKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLGAAVEDIAQFLHQEERLDSTQVGEFLGDSTRFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYDEIEGKKIAMKETKEHTIATKSTKQSVASEKQRRLLYNVEMEQMAKTAKALMEAVSHAKAPFTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAVRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREGSLKGHSLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELASPHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCIAQMVSSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVSTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYTSDDMNVAPGDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKSYGHTFAKHWWQDLFRIVFRIFDNMKLPEQQSEKSEWMTTTCNHALYAICDVFTQFYEALHEVLLSDVFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAVWDETCNCMLDIFKTTIPHVLLTWRPAGMEEEVSDRHLDVDLDRQSLSSIDRNASERGQSQLSNPTDDSWKGAPYAHQKLLASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHMVAAQQDTLDAEIHIETENQGMYKFMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWDEIQQRLLRVCSEALAYFITVNSESHREAWTSLLLLLLTKTLKISDEKFKAHASMYYPYLCEIMQFDLIPELRAVLRKFFLRIGLVYKIWIPEEPSQVPAALSSTW", "length": 1792 }, "evidence": [ { "id": "A0A5G2QXW0", "url": "https://omabrowser.org/oma/group/A0A5G2QXW0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E7FCG1-1", "protein_name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 2", "gene_name": "arfgef2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKEQEALATHRRHTQTESLSTKSMFLSRALEKILADKEVKRSQHNQLRKACQVALDEIKHELEKQKDGTVVPPRANYIEADKYVLPFELACQSKSPRIVSTSLDCLQKLIAYGHITGNAPDSAAPGKRLIDRLVETICNCFQGPQTDEGVQLQIIKALLTAVTSPHIEIHEGTILLTVRTCYNIYLASRNLINQTTAKATLTQMLNVIFTRMENQAALEAQEAEKERQRLQLRNPSPVSSNPSPVNQNPSQTPGRGSGSPWMGRACSEQNGSPCLSPPGVPSTPSTPQDSSSINSRPEEEFATDKQSTKDITHPDEELQESDQTTVDPSVTGGVEGEETHPQSETEAGSEVLEETEPDSGLGDSSVEGGLDQHSDSETRMPPPVVRVDTQQMNGMVDDRGSESSTDMLDAESIHGSQTAARFSHILQKDAFLVFRSLCKLSMKPLADGPPDPKSHELRSKVVSLQLLLSVLQGAGPVFRTHEMFVNAIKQYLCVALSKNGVSSVPEVFELSLAIFLTLLSHFKVHLKMQIEVFFREIFLTILETSSSSFEHKWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGQELGMTPLQELSLRKKGLECLVSILKCMVEWSRDMYVNPNLQANLGQERPAEGDSADVKLSEHLSSRRDSVSSLDSTVSSGVQQSQPDHPEQYEVIKQQKEIIEHGIELFNKKPKRGLQYLQEQGMLGTSPEDIAQFLQQEERLDTTQVGEFLGENVKFNKEVMYCYVDRLDFCGKDFVSALRAFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYDEIAGKKIAMKESKEYSITPKSSKQNVANEKQRRLLYNMEMEQMAKTAKALMEAVSHAQAPFFSATHLEHVRPMFKLAWTPLLAAFSVGLQDCDDQDVASLCLEGIRCAIRIACIFNMQLERDAYIQALARFTLLTASSSITEMKQKNIDTIKTLIMVAHTDGNYLGNSWHEILRCISQLELAQLIGTGVKMRISGVVRDQGGGIKGFPSGGEEFMPLGLGTLVGGPDKRQMAHIQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELASAHQPRMFSLQKIVEISYYNMNRIRLQWSRIWQVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIVKKNRSPTIRDMVIRCVAQMVNSQAANIRSGWKNIFSVFHQAASDHDENIVDLAFQTTGHIVMNTFQQHFAAAIDSFQDAVKCLSEFVCNAAFPDTSMEAIRLIRHCAKYVSERPQALREYTSDDMNVAPGDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWHDLFRIIFRIFDNMKLPEQQTEKTEWMTTTCNHALYAICDVFTQFYEPLSEVLLADIFAQLQWCVKQDNEQLARSGTNCLENLVILNGEKFSPEVWDVTCSCMLDIFQTTSPHALLTWRPAGQEEEVGEGKHMDVEVDSQSQSSFERTLSERGHSQMSTASDETWKGKSHTRVSDHRLFAGLLIKCVVQLELIQTIDNIVFYPATSKREDAENMAAAQRDALEQAEEGEAEVDQGMYRHLSSQHLFKLLDCLLESHRFAKDFNSNNEQRTALWRAGFKGKSKPNLLKQETSSLACSLRILFRMYSDTQLRDSWPDIQTRLLHVCSEALAYFISLTSESHREAWTSLLLLLLTRTLRLPDDKFKPHASCYYHHLCEMMQFDLIPELRAVLRRFFLRIGSVFHIAAPELGQAQPSSSSSSS", "length": 1846 }, "evidence": [ { "id": "A0A5G2QXW0", "url": "https://omabrowser.org/oma/group/A0A5G2QXW0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F4JSZ5-1", "protein_name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 1", "gene_name": "BIG1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSSQNLGGATRCGRVIGPSLDKIIKNAAWRKHTFLVSACKSVLDKLEALSDSPDPSSPLFGLTTSDADAVLQPLLLSLDTGYAKVIEPALDCSFKLFSLSLLRGEVCSSSPDSLLYKLIHAICKVCGIGEESIELAVLRVLLAAVRSPRILIRGDCLLHLVRTCYNVYLGGFNGTNQICAKSVLAQIMLIVFTRSEANSMDASLKTVNVNDLLAITDKNVNEGNSVHICQGFINDVITAGEAAPPPDFALVQPPEEGASSTEDEGTGSKIREDGFLLFKNLCKLSMKFSSQENTDDQILVRGKTLSLELLKVIIDNGGPIWLSDERFLNAIKQLLCLSLLKNSALSVMSIFQLQCAIFTTLLRKYRSGMKSEVGIFFPMLVLRVLENVLQPSFVQKMTVLSLLENICHDPNLIIDIFVNFDCDVESPNIFERIVNGLLKTALGPPPGSSTILSPVQDITFRHESVKCLVSIIKAMGTWMDQQLSVGDSLLPKSLENEAPANNHSNSNEEDGTTIDHDFHPDLNPESSDAATLEQRRAYKIERQKGVTLFNRKPSKGIEFLISSKKVGNSPDEVVSFLRNTTGLNATMIGDYLGEREDFPMKVMHAYVDSFDFKEMNFGEAIRFFLRGFRLPGEAQKIDRIMEKFAERFCKCNPNSFSSADTAYVLAYSVIMLNTDAHNIMVKEKMTKADFIRNNRGIDDGKDLPEEYLGALYDQVVINEIKMSSDSSAPESRQSNGLNKLLGLDGILNLVYWTQTEEKAVGANGLLIKDIQEKFRSKSGKSESAYHVVTDVAILRFMVEVSWGPMLAAFSVTLDQSDDRLAAVECLRGFRYAVHVTAVMGMQTQRDAFVTSMAKFTNLHCAGDMKQKNVDAVKAIISIAIEDGNHLQDAWEHILTCLSRIEHLQLLGEGAPSDASYFASTETEEKKALGFPNLKKKGALQNPVMMAVVRGGSYDSSTIGPNMPGLVKQDQINNFIANLNLLDQIGSFQLNNVYAHSQRLKTEAIVAFVKALCKVSMSELQSPTDPRVFSLTKLVEIAHYNMNRIRLVWSRIWSILSDFFVSVGLSENLSVAIFVMDSLRQLSMKFLEREELANYNFQNEFLRPFVIVMQKSSSAEIRELIVRCISQMVLSRVSNVKSGWKSVFKVFTTAAADERKNIVLLAFETMEKIVREYFSYITETEATTFTDCVRCLITFTNSTFTSDVSLNAIAFLRFCALKLADGGLVWNEKGRSSSPSTPVTDDHSPSTQNFMDADENISYWVPLLTGLSKLTSDSRSAIRKSSLEVLFNILKDHGHIFSRTFWIGVFSSVIYPIFNSVWGENDLLSKDEHSSFPSTFSSHPSEVSWDAETSAMAAQYLVDLFVSFFTVIRSQLSSVVSLLAGLIRSPAQGPTVAGVGALLRLADELGDRFSENEWKEIFLAVNEAASLTLSSFMKTLRTMDDIPDEDTLSDQDFSNEDDIDEDSLQTMSYVVARTKSHITVQLQVVQVVTDLYRIHQQSLLASHVTVILEILSSISSHAHQLNSDLILQKKVRRACSILELSEPPMLHFENDTFQNYLDILQAIVTNNPGVSLELNVESQLMTVCMQILKMYLKCTLFQGDELEETRQPKNWILPMGAASKEEAAARSPLVVAVLKALRELKRDSFKRYAPNFFPLLVELVRSEHSSSQVPQVLSTVFHTCMGAMMDE", "length": 1687 }, "evidence": [ { "id": "A0A5G2QXW0", "url": "https://omabrowser.org/oma/group/A0A5G2QXW0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q7TSU1-1", "protein_name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 2", "gene_name": "Arfgef2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQESQTKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAELEKQRLGAAAPPKANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETVCNCFQGPQTDEGVQLQIIKALLTAVTSPHIEIHEGTILQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTRMENQVLQEARELEKPIQSKPQSPVIQATAGSPKFSRLKQSQAQSKPTTPEKTELPNGDHARSSLGKVNSENGEAHRERGSSISGRAEPSGGSDNGAQEVVKDILEDVVTSAVKEAAEKQGLPEPDQAPGVPECQECTVPPAVDENSQTNGIADDRQSLSSADNLEPDAQGHPVAARFSHILQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRSHEMFVTAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGHELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQATLGQERLPDQEMGDGKGLDMARRCSVTSVESTVSSGTQTAIPDDPEQFEVIKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLGAAVEDIAQFLHQEERLDSTQVGEFLGDSTRFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKKIAMKETKEHTMATKSTKQNVASEKQRRLLYNVEMEQMAKTAKALMEAVSHAKAPFTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAVRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREGSLKGHSLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELASPHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCIAQMVSSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVSTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYTSDDMNVAPGDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKSYGHTFAKHWWQDLFRIVFRIFDNMKLPEQQSEKSEWMTTTCNHALYAICDVFTQFYEALHEVLLSDVFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAVWDETCNCMLDIFRTTIPHVLLTWRPAGMEEEVSDRHLDVDLDRQSLSSIDRNASERGQSQLSNPTDDSWKGAPYANQKLLASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHMVAAQQDTLDADIHIETENQGMYKFMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWGEIQQRLLTVCSEALAYFITVNSESHREAWTSLLLLLLTKTLKINDEKFKAHASVYYPYLCEMMQFDLIPELRAVLRKFFLRIGLVYKIWVPEEPSQVPAASTAW", "length": 1791 }, "evidence": [ { "id": "A0A5G2QXW0", "url": "https://omabrowser.org/oma/group/A0A5G2QXW0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y6D5-1", "protein_name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 2", "gene_name": "ARFGEF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQESQTKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAEIEKQRLGTAAPPKANFIEADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETICSCFQGPQTDEGVQLQIIKALLTAVTSPHIEIHEGTILQTVRTCYNIYLASKNLINQTTAKATLTQMLNVIFTRMENQVLQEARELEKPIQSKPQSPVIQAAAVSPKFVRLKHSQAQSKPTTPEKTDLTNGEHARSDSGKVSTENGDAPRERGSSLSGTDDGAQEVVKDILEDVVTSAIKEAAEKHGLTEPERVLGELECQECAIPPGVDENSQTNGIADDRQSLSSADNLESDAQGHQVAARFSHVLQKDAFLVFRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRTHEMFINAIKQYLCVALSKNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGHELGMTPLQELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQTSLGQERLTDQEIGDGKGLDMARRCSVTSMESTVSSGTQTTVQDDPEQFEVIKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLGTSVEDIAQFLHQEERLDSTQVGDFLGDSARFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKKIAMKETKELTIATKSTKQNVASEKQRRLLYNLEMEQMAKTAKALMEAVSHAKAPFTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLERDAYVQALARFSLLTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSGREREGSLKGHTLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELASPHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMAIRCIAQMVNSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTCHIVTTIFQHHFPAAIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYTSDDMNVAPGDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWQDLFRIVFRIFDNMKLPEQLSEKSEWMTTTCNHALYAICDVFTQFYEALNEVLLSDVFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPEVWDETCNCMLDIFKTTIPHVLLTWRPVGMEEDSSEKHLDVDLDRQSLSSIDKNPSERGQSQLSNPTDDSWKGRPYANQKLFASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHMVAAQQDTLDADIHIETEDQGMYKYMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLACCLRILFRMYVDENRRDSWEEIQQRLLTVCSEALAYFITVNSESHREAWTSLLLLLLTKTLKINDEKFKAHASMYYPYLCEIMQFDLIPELRAVLRKFFLRIGVVYKIWIPEEPSQVPAALSPVW", "length": 1785 }, "evidence": [ { "id": "A0A5G2QXW0", "url": "https://omabrowser.org/oma/group/A0A5G2QXW0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "receptor recycling", "id": "GO:0001881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001881", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" }, { "name": "protein kinase A regulatory subunit binding", "id": "GO:0034237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034237", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1194, "end_pos": 1196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1518, "end_pos": 1520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 805, "end_pos": 807, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QXW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW0" }, { "id": "PS50190", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50190" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEC7", "eco_id": "ECO_0000259", "start_pos": 636, "end_pos": 825, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1194, "end_pos": 1196 }, { "start_pos": 1518, "end_pos": 1520 }, { "start_pos": 178, "end_pos": 180 }, { "start_pos": 805, "end_pos": 807 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXW3-1", "uniprot_ac": "A0A5G2QXW3", "uniprot_id": "A0A5G2QXW3_PIG", "mass": { "chemical_mass": 34607.0, "monoisotopic_mass": 34607.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "LINE-1 type transposase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2QXW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3", "locus": {} } ], "crossref": [ { "id": "A0A5G2QXW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041325", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041325", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QXW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSLTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKIFPNKQKLKEYSNTNPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2QXW3-1|A0A5G2QXW3_PIG Isoform 1 of LINE-1 type transposase domain-containing protein 1 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QXW3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QXW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3/entry#A0A5G2QXW3-1", "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSLTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKIFPNKQKLKEYSNTNPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2QXW3-1|A0A5G2QXW3_PIG Isoform 1 of LINE-1 type transposase domain-containing protein 1 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QXW3-1" }, "locus": { "chromosome": "4", "start_pos": 60167466, "end_pos": 60166579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087625.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087625.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068982.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068982.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QXW3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 296, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QXW3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXW3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QXW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 227, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QXW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3" }, { "id": "PF17490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element dsRBD-like", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 293, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QXW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXW3" }, { "id": "PF17489", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element trimerization", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 128, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QXX8-1", "uniprot_ac": "A0A5G2QXX8", "uniprot_id": "A0A5G2QXX8_PIG", "mass": { "chemical_mass": 35150.0, "monoisotopic_mass": 35150.0 }, "refseq": { "ac": "XP_020938669", "name": "olfactory receptor 1052-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938669" }, "gene_names": [ { "name": "LOC110259258", "type": "recommended", "evidence": [ { "id": "A0A5G2QXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8" } ] }, { "name": "LOC110259258", "type": "synonym", "evidence": [ { "id": "XP_020938669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938669" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1052-like", "type": "synonym", "evidence": [ { "id": "XP_020938669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938669" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259258", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QXX8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXX8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044923", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044923", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15230", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15230", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110259258", "url": "https://www.ncbi.nlm.nih.gov/gene/110259258", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110259258", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259258", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QXX8", "url": "https://www.orthodb.org/?gene=A0A5G2QXX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020938669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938669", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QXX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALGQNHTTVTRFILLGLTDQAHQKPLLFALFLLVYLVTLVGNLGLIDLIRTSAPLHTPMYFLLSVLSVLDVCNSSSFTPRLLVSLLATDRSISFSGCAVQMALLNIFGTEECLLLSVMAYDRFVAICRPLLYHTIMSKHLCVRLVLATCAVVTLNSVLQTGNVFILPYCGPNIIDHYMCDIPPLLHLACSDTATANVILLVLSASVTLPTISVIVVSYAYILGTICRMRSLQAQSKAFSTCASHLTAVSLFYGSVFLVYVQPDPQRASAYNKILSVFYTIVIPMLNPLVYSLRNKDVKAAVQARGLRLHTRGMCQKGLW", "length": 320, "header": "tr|A0A5G2QXX8-1|A0A5G2QXX8_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110259258 PE=3 SV=1 CANONICAL=A0A5G2QXX8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QXX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8/entry#A0A5G2QXX8-1", "sequence": { "sequence": "MALGQNHTTVTRFILLGLTDQAHQKPLLFALFLLVYLVTLVGNLGLIDLIRTSAPLHTPMYFLLSVLSVLDVCNSSSFTPRLLVSLLATDRSISFSGCAVQMALLNIFGTEECLLLSVMAYDRFVAICRPLLYHTIMSKHLCVRLVLATCAVVTLNSVLQTGNVFILPYCGPNIIDHYMCDIPPLLHLACSDTATANVILLVLSASVTLPTISVIVVSYAYILGTICRMRSLQAQSKAFSTCASHLTAVSLFYGSVFLVYVQPDPQRASAYNKILSVFYTIVIPMLNPLVYSLRNKDVKAAVQARGLRLHTRGMCQKGLW", "length": 320, "header": "tr|A0A5G2QXX8-1|A0A5G2QXX8_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110259258 PE=3 SV=1 CANONICAL=A0A5G2QXX8-1" }, "locus": { "chromosome": "2", "start_pos": 13053867, "end_pos": 13052908, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078043.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078043.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069733.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069733.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110259258", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259258", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QXX8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QXX8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QXX8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QY04-1", "uniprot_ac": "A0A5G2QY04", "uniprot_id": "A0A5G2QY04_PIG", "mass": { "chemical_mass": 35017.0, "monoisotopic_mass": 35017.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100524192", "type": "recommended", "evidence": [ { "id": "A0A5G2QY04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QY04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY04", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY04", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100524192", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04", "locus": {} } ], "crossref": [ { "id": "A0A5G2QY04", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QY04", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QY04", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY04-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPNNVTEFVLLGFTQNPHLRKIFFIVFLFIFLFTLLSNMFIVIIISLSPTLSAPMYFFLTYLAFIDTSLSSVTTPKITIDLLYQRTTVSWGGCLTQLFLEHFLGGSEIIVLIAMAYDRYVAICKPLHYTTIMRHGLCQLLVVVAWIGGILHGTVQILFVLDLPFCGPNIINHFMCDFFSLFELACSDTYWRAIVISANSGGMCLLIFFMLLISYMVILSSLKSHGSEGRRKALSTCGSHFTVVVLFFVPCIFIYVRPVATYPVDKLVSLFYGTFTPMLNPIIYTVRNTEVKNAMKGLLKRRVTWVVPGA", "length": 310, "header": "tr|A0A5G2QY04-1|A0A5G2QY04_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524192 PE=3 SV=1 CANONICAL=A0A5G2QY04-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QY04-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04/entry#A0A5G2QY04-1", "sequence": { "sequence": "MPPNNVTEFVLLGFTQNPHLRKIFFIVFLFIFLFTLLSNMFIVIIISLSPTLSAPMYFFLTYLAFIDTSLSSVTTPKITIDLLYQRTTVSWGGCLTQLFLEHFLGGSEIIVLIAMAYDRYVAICKPLHYTTIMRHGLCQLLVVVAWIGGILHGTVQILFVLDLPFCGPNIINHFMCDFFSLFELACSDTYWRAIVISANSGGMCLLIFFMLLISYMVILSSLKSHGSEGRRKALSTCGSHFTVVVLFFVPCIFIYVRPVATYPVDKLVSLFYGTFTPMLNPIIYTVRNTEVKNAMKGLLKRRVTWVVPGA", "length": 310, "header": "tr|A0A5G2QY04-1|A0A5G2QY04_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524192 PE=3 SV=1 CANONICAL=A0A5G2QY04-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 538707, "end_pos": 537778, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070805.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070805.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069801.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069801.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY04", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY04", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY04", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY04", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QY04-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QY04-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QY04" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QY04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY04" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 284, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QY22-1", "uniprot_ac": "A0A5G2QY22", "uniprot_id": "A0A5G2QY22_PIG", "mass": { "chemical_mass": 63063.0, "monoisotopic_mass": 63063.0 }, "refseq": {}, "gene_names": [ { "name": "ANTXRL", "type": "recommended", "evidence": [ { "id": "A0A5G2QY22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22" } ] } ], "protein_names": [ { "name": "ANTXR like", "type": "synonym", "evidence": [ { "id": "A0A5G2QY22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ANTXRL", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22", "locus": {} } ], "crossref": [ { "id": "A0A5G2QY22", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QY22", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000043778", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000043778", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16059", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16059", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16059:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16059:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05587", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05587", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QY22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY22-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRGGLVMPGPTLFLLLVLPPPLLSAGSFQHSGPDWKDLHRLTRDWGNLYRHLIQNEGTFQHLRGPAIWLQENKEKDKDSCQSTYDLYFILDMSGSINNNWMDIYALVEDLVKKFDNPKIRMSFITYSTQGHILMKLTSDKKEIQDGLNRLQNVVPTGNTYMQEGFKKANEQIEQANSGENKVPSMIIALTDGTLESISLQETKQQADRARKLGANVYCIGVKDYETEQLSEIADSSDHVFGVDQGFKALKNIIDPMRGKTALNEYELMISGRGFNNAKSKDEVICRFIFSDKKSIDKKAASVDDTTITCPGVRIEKPDEEVFIEVSLNNGINFICNNVSIISKNCMSSKVSEPDTEVITTLQTTQQPTTQASSSPLPPTSPQFIPYVNSSYFFMIIPGLLLFLLMLWCIWWMCCKKTVKELPPVQKSEREPEEVCHMQTCPTVIVPCGCQGGGIKRMEGKLDSLCDFVQRCNQMPLMWYTPRDMGRCVNFSLMKPYCGQLPCSPKICLHPSRECFRINSYCSRCQHPPTTCSRLPSRVLPHISPNSRSLCGATLSLQPP", "length": 560, "header": "tr|A0A5G2QY22-1|A0A5G2QY22_PIG Isoform 1 of ANTXR like OS=Sus scrofa OX=9823 GN=ANTXRL PE=3 SV=2 CANONICAL=A0A5G2QY22-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QY22-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22/entry#A0A5G2QY22-1", "sequence": { "sequence": "MGRGGLVMPGPTLFLLLVLPPPLLSAGSFQHSGPDWKDLHRLTRDWGNLYRHLIQNEGTFQHLRGPAIWLQENKEKDKDSCQSTYDLYFILDMSGSINNNWMDIYALVEDLVKKFDNPKIRMSFITYSTQGHILMKLTSDKKEIQDGLNRLQNVVPTGNTYMQEGFKKANEQIEQANSGENKVPSMIIALTDGTLESISLQETKQQADRARKLGANVYCIGVKDYETEQLSEIADSSDHVFGVDQGFKALKNIIDPMRGKTALNEYELMISGRGFNNAKSKDEVICRFIFSDKKSIDKKAASVDDTTITCPGVRIEKPDEEVFIEVSLNNGINFICNNVSIISKNCMSSKVSEPDTEVITTLQTTQQPTTQASSSPLPPTSPQFIPYVNSSYFFMIIPGLLLFLLMLWCIWWMCCKKTVKELPPVQKSEREPEEVCHMQTCPTVIVPCGCQGGGIKRMEGKLDSLCDFVQRCNQMPLMWYTPRDMGRCVNFSLMKPYCGQLPCSPKICLHPSRECFRINSYCSRCQHPPTTCSRLPSRVLPHISPNSRSLCGATLSLQPP", "length": 560, "header": "tr|A0A5G2QY22-1|A0A5G2QY22_PIG Isoform 1 of ANTXR like OS=Sus scrofa OX=9823 GN=ANTXRL PE=3 SV=2 CANONICAL=A0A5G2QY22-1" }, "locus": { "chromosome": "14", "start_pos": 88379488, "end_pos": 88342211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073450.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073450.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063103.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063103.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QY22-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 560, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QY22-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QY22" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QY22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY22" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 257, "start_aa": "Asp", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 338, "end_pos": 340 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 490, "end_pos": 492 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QY67-1", "uniprot_ac": "A0A5G2QY67", "uniprot_id": "A0A5G2QY67_PIG", "mass": { "chemical_mass": 191958.0, "monoisotopic_mass": 191958.0 }, "refseq": {}, "gene_names": [ { "name": "CFAP43", "type": "recommended", "evidence": [ { "id": "A0A5G2QY67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY67" } ] } ], "protein_names": [ { "name": "Cilia- and flagella-associated protein 43", "type": "recommended", "evidence": [ { "id": "A0A5G2QY67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY67/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY67" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CFAP43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY67", "locus": { "chromosome": "14", "start_pos": 115073366, "end_pos": 115174043, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010609", "url": "https://www.ensembl.org/id/ENSSSCG00000010609" } ] } } ], "crossref": [ { "id": "ENSSSCG00000010609", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010609", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14885", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14885", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14885:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14885:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25828", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25828", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QY67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY67-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQGRERDESHSVAIGASLSVRWVQGFPKQNIHFVNDSTFCYPCGNFIIFINIETKKRTVLQCINGIVGVMATNIPYEVVAFSDRRLRPLIYIYNFPGLTRRTKLKGNVLLDYTLLSFSYCGTYLASYSSLPEFELALWNWELGVILCKKSQPGVDVSQMTFNPMNWCQLCLSSPSAVTVWTIERCNQEHYLKAKSVKLPMEDGSFFNETDVIFPQSLPKDLIYGPVLPVSAIAGLVGEEAETFRPKDDLYTLLHPTMHCWTPTSDLYIGCEEGHLLMINGENLKATVLSKMEDGTPNIGRSHISPVTMVYQKGGVLASGIDGFVYSFLIKDTNYKVEDFLEIEEPVEHLIFSPSYKMLLIQTDKGSVYIYTFGEEPTFEKILEACDGKFQATDFITPRSEYCMTLTASGEVCIWDIEDGLCASRIYLKIPATVLACSPSSLSAAVGTKDGFVHFLDVRNVESPQAVHKAFLSESPVQHLLYDQRGMYLLVGTSEGYIFVINAKPSSLFQILGFIEIGKGILQISTVSLLEKDIVKVMVLYPLPDTGRSRLEIFTLPKIIPQVSASFADERGRLRDELIHKFVYEIEHTLSSAVLNFQSNRIYGFCNQVPYICSYLLPEKEHGGVCILKPYQKVQSKQYGSGMLSLSPHGLWLITIAKCGILCVRDIHTLEVFARCRSHSHQGHGIQSVRISMDGQNILVNGRNDSTLVNLRWRRFGGHLANEILEYNQQLLTFLTNIMDEENDYLSITQRDSLVLESASEHTNRRSSTDSSQEELVQVGNTEAIPWIQQKSQEAIKKEVKLFSNKRKEIKRKIKALAKTVLDMMEENEAVDNIAKLEQQEFGLDLEELERLHHKSEEEVAKIRKDVEMQNLAKRYLAELIKEECWNSMAVKGRALKCFHIPYVVENFPMKERTDEELKELKRVVQQKKIEAECLKLRKEIVEVQSAITMVKKHHEEEDEEEEEDGTTKDTNLPNYLLGSLSTDFRVHTSLLSSQLELHSREEKINQIILLKDIIYKVKTTFNSEFDAAYKQKEFEIARVKEKNVRIQEIILDLELEESVWQPEFEDCEKPERTLVVKSSEITAHKHINPWQKSKTELLVAHEMEQSLLTRGSDARRRALMDMMGGVLEVKKEDILRMVIPQPAFMAKPDALWSEEERKQFKEYEKKVKDLNEERDKYRKSLEAEMKKLQNSIQENTQNFDEHLKKLFERRVKAEMVVNQEELKINNLVFSLLLDEEISSRETFLNNYLTRKQEEKSQTAEVVRKSREDLDVYKEHYDNLLAEDKVLDRSFKKEFSEIPSHQVDILYKLFKRRPRIHRQKVHADTTSLVPFGERPGSGKLNKDAFAQLMKAMDDLDNINNMPEGLDPSVWEHFCVTRRAKVENEQKVKQKAAGLMEMVAFLRRRTEDDERVQQEIEKVLHELVLLQEDKVKFQLNLTIQILLKQGQVELENFQFLLEYPDAILINKNIIEDLNSVIRTQGQKKVASMMESKNVHKGIFQIEWEHKKMEMEMEDLNQKAWDIQMLFFSRDRQKFLNEPNYETLIAIQIGIMEQTIAVLDKTHKKNVENCKKLLKKLGRCSSQKDVANYTLSCSLREELVAVSERKDICNAVGSKLTCEKIAKERYENMMQQQKLTKISKEQAEQISILQAEVERLRMKTFPALVQM", "length": 1665, "header": "tr|A0A5G2QY67-1|A0A5G2QY67_PIG Isoform 1 of Cilia- and flagella-associated protein 43 OS=Sus scrofa OX=9823 GN=CFAP43 PE=3 SV=2 CANONICAL=A0A5G2QY67-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QY67-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY67/entry#A0A5G2QY67-1", "sequence": { "sequence": "MAQGRERDESHSVAIGASLSVRWVQGFPKQNIHFVNDSTFCYPCGNFIIFINIETKKRTVLQCINGIVGVMATNIPYEVVAFSDRRLRPLIYIYNFPGLTRRTKLKGNVLLDYTLLSFSYCGTYLASYSSLPEFELALWNWELGVILCKKSQPGVDVSQMTFNPMNWCQLCLSSPSAVTVWTIERCNQEHYLKAKSVKLPMEDGSFFNETDVIFPQSLPKDLIYGPVLPVSAIAGLVGEEAETFRPKDDLYTLLHPTMHCWTPTSDLYIGCEEGHLLMINGENLKATVLSKMEDGTPNIGRSHISPVTMVYQKGGVLASGIDGFVYSFLIKDTNYKVEDFLEIEEPVEHLIFSPSYKMLLIQTDKGSVYIYTFGEEPTFEKILEACDGKFQATDFITPRSEYCMTLTASGEVCIWDIEDGLCASRIYLKIPATVLACSPSSLSAAVGTKDGFVHFLDVRNVESPQAVHKAFLSESPVQHLLYDQRGMYLLVGTSEGYIFVINAKPSSLFQILGFIEIGKGILQISTVSLLEKDIVKVMVLYPLPDTGRSRLEIFTLPKIIPQVSASFADERGRLRDELIHKFVYEIEHTLSSAVLNFQSNRIYGFCNQVPYICSYLLPEKEHGGVCILKPYQKVQSKQYGSGMLSLSPHGLWLITIAKCGILCVRDIHTLEVFARCRSHSHQGHGIQSVRISMDGQNILVNGRNDSTLVNLRWRRFGGHLANEILEYNQQLLTFLTNIMDEENDYLSITQRDSLVLESASEHTNRRSSTDSSQEELVQVGNTEAIPWIQQKSQEAIKKEVKLFSNKRKEIKRKIKALAKTVLDMMEENEAVDNIAKLEQQEFGLDLEELERLHHKSEEEVAKIRKDVEMQNLAKRYLAELIKEECWNSMAVKGRALKCFHIPYVVENFPMKERTDEELKELKRVVQQKKIEAECLKLRKEIVEVQSAITMVKKHHEEEDEEEEEDGTTKDTNLPNYLLGSLSTDFRVHTSLLSSQLELHSREEKINQIILLKDIIYKVKTTFNSEFDAAYKQKEFEIARVKEKNVRIQEIILDLELEESVWQPEFEDCEKPERTLVVKSSEITAHKHINPWQKSKTELLVAHEMEQSLLTRGSDARRRALMDMMGGVLEVKKEDILRMVIPQPAFMAKPDALWSEEERKQFKEYEKKVKDLNEERDKYRKSLEAEMKKLQNSIQENTQNFDEHLKKLFERRVKAEMVVNQEELKINNLVFSLLLDEEISSRETFLNNYLTRKQEEKSQTAEVVRKSREDLDVYKEHYDNLLAEDKVLDRSFKKEFSEIPSHQVDILYKLFKRRPRIHRQKVHADTTSLVPFGERPGSGKLNKDAFAQLMKAMDDLDNINNMPEGLDPSVWEHFCVTRRAKVENEQKVKQKAAGLMEMVAFLRRRTEDDERVQQEIEKVLHELVLLQEDKVKFQLNLTIQILLKQGQVELENFQFLLEYPDAILINKNIIEDLNSVIRTQGQKKVASMMESKNVHKGIFQIEWEHKKMEMEMEDLNQKAWDIQMLFFSRDRQKFLNEPNYETLIAIQIGIMEQTIAVLDKTHKKNVENCKKLLKKLGRCSSQKDVANYTLSCSLREELVAVSERKDICNAVGSKLTCEKIAKERYENMMQQQKLTKISKEQAEQISILQAEVERLRMKTFPALVQM", "length": 1665, "header": "tr|A0A5G2QY67-1|A0A5G2QY67_PIG Isoform 1 of Cilia- and flagella-associated protein 43 OS=Sus scrofa OX=9823 GN=CFAP43 PE=3 SV=2 CANONICAL=A0A5G2QY67-1" }, "locus": { "chromosome": "14", "start_pos": 115173970, "end_pos": 115073664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090212.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090212.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063153.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063153.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY67" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY67" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY67" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of cilium beat frequency", "id": "GO:0003356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003356", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY67" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1435, "end_pos": 1437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1586, "end_pos": 1588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1435, "end_pos": 1437 }, { "start_pos": 1586, "end_pos": 1588 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 704, "end_pos": 706 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYA5-1", "uniprot_ac": "A0A5G2QYA5", "uniprot_id": "A0A5G2QYA5_PIG", "mass": { "chemical_mass": 27178.0, "monoisotopic_mass": 27178.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "exodeoxyribonuclease III", "type": "recommended", "evidence": [ { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5/entry#names_and_taxonomy" } ] }, { "name": "3.1.11.2", "type": "synonym", "evidence": [ { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5", "locus": {} } ], "crossref": [ { "id": "A0A5G2QYA5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000051128", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000051128", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09076", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09076", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22748", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22748", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22748:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22748:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QYA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAIRTYISIINLNVNGLNTPTKRHRLAERIQKQDPHICCLQETHFTSRDTYKLKVKGWKKIVHANGNQKKAGVAILISGKRDFKMNILRDKEGHYIMIKGSIQEEDITILNIYAPNIGSPQYIRQLLTTLKGEINNNTIIVGDVNTPLTAMDRSTRQKTSKETQALNDALDQNDLIDIYRTFHPKATEYTFFSSAHGTFSKIDHILGYKSNLGNFKKIEITSSIVSGHNAIRLEINKKK", "length": 239, "header": "tr|A0A5G2QYA5-1|A0A5G2QYA5_PIG Isoform 1 of exodeoxyribonuclease III OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QYA5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5/entry#A0A5G2QYA5-1", "sequence": { "sequence": "MAIRTYISIINLNVNGLNTPTKRHRLAERIQKQDPHICCLQETHFTSRDTYKLKVKGWKKIVHANGNQKKAGVAILISGKRDFKMNILRDKEGHYIMIKGSIQEEDITILNIYAPNIGSPQYIRQLLTTLKGEINNNTIIVGDVNTPLTAMDRSTRQKTSKETQALNDALDQNDLIDIYRTFHPKATEYTFFSSAHGTFSKIDHILGYKSNLGNFKKIEITSSIVSGHNAIRLEINKKK", "length": 239, "header": "tr|A0A5G2QYA5-1|A0A5G2QYA5_PIG Isoform 1 of exodeoxyribonuclease III OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QYA5-1" }, "locus": { "chromosome": "13", "start_pos": 108782065, "end_pos": 108781349, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083878.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083878.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069118.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069118.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5" } ], "pmid": "" }, { "name": "double-stranded DNA 3'-5' DNA exonuclease activity", "id": "GO:0008311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008311", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QYA5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 239, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QYA5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYA5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5" }, { "id": "PF03372", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endonuclease/exonuclease/phosphatase", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 209, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5#function" }, { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 13, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 13, "end_pos": 13, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5#function" }, { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 143, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 143, "end_pos": 143, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5#function" }, { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 145, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 145, "end_pos": 145, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5#function" }, { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 228, "amino_acid": "His", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 228, "end_pos": 228, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5#function" }, { "id": "A0A5G2QYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA5" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 42, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 42, "end_pos": 42, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYC3-1", "uniprot_ac": "A0A5G2QYC3", "uniprot_id": "A0A5G2QYC3_PIG", "mass": { "chemical_mass": 90530.0, "monoisotopic_mass": 90530.0 }, "refseq": {}, "gene_names": [ { "name": "SYCP2L", "type": "recommended", "evidence": [ { "id": "A0A5G2QYC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3" } ] } ], "protein_names": [ { "name": "Synaptonemal complex protein 2 like", "type": "synonym", "evidence": [ { "id": "A0A5G2QYC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYC3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SYCP2L", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3", "locus": { "chromosome": "7", "start_pos": 7640989, "end_pos": 7574372, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000051558", "url": "https://www.ensembl.org/id/ENSSSCG00000051558" } ] } } ], "crossref": [ { "id": "A0A5G2QYC3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYC3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000051558", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000051558", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR024835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15607", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15607", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15607:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15607:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18584", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18584", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QYC3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQEEKEGPLQSVQEKDGSGLVQDAFYLQSLITDAFHDEGFQKIKEYFQQRENHVPQKYDDLLLHHLNRSISKELDKNEFQYVSLLLKCIQQFFMDGLKEDEPLLIQQGLIPKLVSWFERTADFLTTTELASDASLMSVTEDFYDTALVISRSSSKGKSEMLGSFMFTLGFLVTEGNVNHGIQQEALRALNCILQTVPREERKQLLLSDVPCQLMKDFARTILTVGDYDQQVALCEALCRLTTKKSREDIVHQWFEDDVIAEAFKEIKHQEFETDCRRFLNHLNDRLGDQRRVESFPCIAAFADELEMKKPADEKLEKFWIDFNLGSQSITFYVNNTESALWDSVRLLKDAVITFSVIETEMKVLRIFLKKPVNIGNKEVMKIEIHFELQFDIAQASIKALGEDKQVVMLDQTKTFSDLFEFEEEGTEIPSSHERETDQAKESTELAELSSPEDDHGLATVPLNNQSDPAVSRGSFKYRKHLFSESNQDSSTSSSELSWTSNQKRKALKSYPSRKKTRTRSSVRFVSLLPPSSGSDLEKDQAKILPPLQKDTSRQNSTTPPKISGTKFQNSSAFLTPEDSAQKTELQSPHPLSNLSSLEPSDLEENVSKTVAQESLIKSTSFKHKLQNLEDRDRAGGRAAQWKQSRREEGDSPGSLSSVSEEAGLAEGVSTSSLIVMPENPEGSMMIATFENFTQELRRKFELRYRRSLLYSKNAKQAPDCLMKLLNQIRQRRLKKLEQFRSFVLQEASNLEKDIQGLWRLEEDVLEFWGKQSDDLKSFCDLQLLRLNPVQPS", "length": 792, "header": "tr|A0A5G2QYC3-1|A0A5G2QYC3_PIG Isoform 1 of Synaptonemal complex protein 2 like OS=Sus scrofa OX=9823 GN=SYCP2L PE=3 SV=1 CANONICAL=A0A5G2QYC3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3/entry#A0A5G2QYC3-1", "sequence": { "sequence": "MQEEKEGPLQSVQEKDGSGLVQDAFYLQSLITDAFHDEGFQKIKEYFQQRENHVPQKYDDLLLHHLNRSISKELDKNEFQYVSLLLKCIQQFFMDGLKEDEPLLIQQGLIPKLVSWFERTADFLTTTELASDASLMSVTEDFYDTALVISRSSSKGKSEMLGSFMFTLGFLVTEGNVNHGIQQEALRALNCILQTVPREERKQLLLSDVPCQLMKDFARTILTVGDYDQQVALCEALCRLTTKKSREDIVHQWFEDDVIAEAFKEIKHQEFETDCRRFLNHLNDRLGDQRRVESFPCIAAFADELEMKKPADEKLEKFWIDFNLGSQSITFYVNNTESALWDSVRLLKDAVITFSVIETEMKVLRIFLKKPVNIGNKEVMKIEIHFELQFDIAQASIKALGEDKQVVMLDQTKTFSDLFEFEEEGTEIPSSHERETDQAKESTELAELSSPEDDHGLATVPLNNQSDPAVSRGSFKYRKHLFSESNQDSSTSSSELSWTSNQKRKALKSYPSRKKTRTRSSVRFVSLLPPSSGSDLEKDQAKILPPLQKDTSRQNSTTPPKISGTKFQNSSAFLTPEDSAQKTELQSPHPLSNLSSLEPSDLEENVSKTVAQESLIKSTSFKHKLQNLEDRDRAGGRAAQWKQSRREEGDSPGSLSSVSEEAGLAEGVSTSSLIVMPENPEGSMMIATFENFTQELRRKFELRYRRSLLYSKNAKQAPDCLMKLLNQIRQRRLKKLEQFRSFVLQEASNLEKDIQGLWRLEEDVLEFWGKQSDDLKSFCDLQLLRLNPVQPS", "length": 792, "header": "tr|A0A5G2QYC3-1|A0A5G2QYC3_PIG Isoform 1 of Synaptonemal complex protein 2 like OS=Sus scrofa OX=9823 GN=SYCP2L PE=3 SV=1 CANONICAL=A0A5G2QYC3-1" }, "locus": { "chromosome": "7", "start_pos": 7640986, "end_pos": 7574372, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072383.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072383.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069138.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069138.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYC3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYC3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3" } ], "pmid": "" }, { "name": "condensed chromosome, centromeric region", "id": "GO:0000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000779", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYC3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3" } ], "pmid": "" }, { "name": "lateral element", "id": "GO:0000800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000800", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYC3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 605, "end_pos": 607, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 691, "end_pos": 693, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QYC3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 792, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QYC3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYC3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3" }, { "id": "PF18584", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18584" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Synaptonemal complex protein 2 Spt16M-like", "eco_id": "ECO_0000259", "start_pos": 292, "end_pos": 402, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QYC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYC3" }, { "id": "PF18581", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18581" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Synaptonemal complex protein 2 armadillo-repeat-like", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 200, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 334, "end_pos": 336 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 569, "end_pos": 571 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 605, "end_pos": 607 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 691, "end_pos": 693 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYD0-1", "uniprot_ac": "A0A5G2QYD0", "uniprot_id": "A0A5G2QYD0_PIG", "mass": { "chemical_mass": 35082.0, "monoisotopic_mass": 35082.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110257984", "type": "recommended", "evidence": [ { "id": "A0A5G2QYD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QYD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYD0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYD0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110257984", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0", "locus": {} } ], "crossref": [ { "id": "A0A5G2QYD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF78", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF78", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QYD0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNLTIISLTSTDSHLQTAMYFFLQNFSFLEIAFTSACIPKYLYNISTGDKTITYNSCATQLFFTDLFAVTEFFLLAAMSYDRYVAICKPLHYVTIVNHTVCRRLIIGSWLAGLLIIIPPFSLGLKLEFCDSNVIDYFFCDLAPLLKISCSETWLIEETVTVCAVLAFIMTLVCVVLSYVYILKTILQFSSAQQRKKAFSTCSSHMIVVSISYGSCIFIYVKPSPKDSLAVNKGVTLLTTSIAPMLSPFIYTLRNKQVKQAFNDAIKRTALFKKD", "length": 311, "header": "tr|A0A5G2QYD0-1|A0A5G2QYD0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110257984 PE=3 SV=1 CANONICAL=A0A5G2QYD0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0/entry#A0A5G2QYD0-1", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNLTIISLTSTDSHLQTAMYFFLQNFSFLEIAFTSACIPKYLYNISTGDKTITYNSCATQLFFTDLFAVTEFFLLAAMSYDRYVAICKPLHYVTIVNHTVCRRLIIGSWLAGLLIIIPPFSLGLKLEFCDSNVIDYFFCDLAPLLKISCSETWLIEETVTVCAVLAFIMTLVCVVLSYVYILKTILQFSSAQQRKKAFSTCSSHMIVVSISYGSCIFIYVKPSPKDSLAVNKGVTLLTTSIAPMLSPFIYTLRNKQVKQAFNDAIKRTALFKKD", "length": 311, "header": "tr|A0A5G2QYD0-1|A0A5G2QYD0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110257984 PE=3 SV=1 CANONICAL=A0A5G2QYD0-1" }, "locus": { "chromosome": "AEMK02000164.1", "start_pos": 67256, "end_pos": 66324, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083630.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083630.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069888.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069888.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYD0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYD0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYD0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYD0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QYD0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QYD0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYD0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYD0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYF1-1", "uniprot_ac": "A0A5G2QYF1", "uniprot_id": "A0A5G2QYF1_PIG", "mass": { "chemical_mass": 230503.0, "monoisotopic_mass": 230503.0 }, "refseq": {}, "gene_names": [ { "name": "DSCAML1", "type": "recommended", "evidence": [ { "id": "A0A5G2QYF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ] } ], "protein_names": [ { "name": "Cell adhesion molecule DSCAML1", "type": "recommended", "evidence": [ { "id": "A0A5G2QYF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells. Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1#function" }, { "database": "UniProtKB", "id": "ARBA00058976", "url": "https://www.uniprot.org/uniprotkb/ARBA00058976#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DSCAML1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1", "locus": { "chromosome": "9", "start_pos": 44785701, "end_pos": 45147140, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015082", "url": "https://www.ensembl.org/id/ENSSSCG00000015082" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015082", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015082", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05734", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05734", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05735", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05735", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-376172", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-376172", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LMQ3", "url": "https://www.uniprot.org/uniprotkb/I3LMQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LMQ3-1", "url": "https://www.uniprot.org/uniprotkb/I3LMQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGAREPRREEPPPPPSAGLRSRESGARSAGGWERAERGRGAAARPATGPPPRRIGPLYGMWLVTFLLLLDSLHKARPEDVGTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAENAAGKIRSPNIRVKAVFREPYTVRVEDQRSMRGSVAVFKCLIPSSVQEYVSVVSWEKDTVAIIPENRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGTLTVIDPLHVTLTPKKLKTGIGSTVILSCTLMGSPEFTIRWYRNTELVLPGEAISIRGLSNETLLITSAQKSHSGAYQCFASRKAQTAQDFAIIVLEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRSNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMRDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEWKDVFVSSSERSFRLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQGLRANSSGEVFLTELREATWYELRMRACNSAGCGNETAQFATLDYDGSTIPPIKSAQGEGDDVKKLFTIGCPVILATLGVALLFIVRKKRKEKRLKRLRDAKSLAEMLISKNNRSFDTPVKGPPQGPRLHIDIPRVQLLIEDKEGIKQLDDKATIPVTDAEFSQAVNPQSFCTGVSLHHPALIQSTGPLIDMSDIRPGTNPVSRKNVKSAHSTRNRYSSQWTLTKCQASTPARTLTSDWRTVGSQHGVTVTESDSYSASLSQDTDKGRNSMVSTESASSTYEELARAYEHAKLEEQLQHAKFEITECFISDSSSDQMTTGTNENADSMTSMSTPSEPGICRFTASPPKPQDADRGKNVAVPIPHRANKSDYCNLPLYAKSEAFFRKADGREPCPVVPPREASIRNLARTYHPQARHLTLDPASKPLGLPHPGAPAAASTATLPQRTLAMPAPPAGTAPPAPPTPAEPPAAPSAAPPAPSTEPPRAGGPHTKMGGSRDSLLEMSTSGVGRSQKQGAGAYSKSYTLV", "length": 2111, "header": "tr|A0A5G2QYF1-1|A0A5G2QYF1_PIG Isoform 1 of Cell adhesion molecule DSCAML1 OS=Sus scrofa OX=9823 GN=DSCAML1 PE=4 SV=1 CANONICAL=A0A5G2QYF1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1/entry#A0A5G2QYF1-1", "sequence": { "sequence": "MTGAREPRREEPPPPPSAGLRSRESGARSAGGWERAERGRGAAARPATGPPPRRIGPLYGMWLVTFLLLLDSLHKARPEDVGTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAENAAGKIRSPNIRVKAVFREPYTVRVEDQRSMRGSVAVFKCLIPSSVQEYVSVVSWEKDTVAIIPENRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGTLTVIDPLHVTLTPKKLKTGIGSTVILSCTLMGSPEFTIRWYRNTELVLPGEAISIRGLSNETLLITSAQKSHSGAYQCFASRKAQTAQDFAIIVLEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRSNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMRDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEWKDVFVSSSERSFRLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQGLRANSSGEVFLTELREATWYELRMRACNSAGCGNETAQFATLDYDGSTIPPIKSAQGEGDDVKKLFTIGCPVILATLGVALLFIVRKKRKEKRLKRLRDAKSLAEMLISKNNRSFDTPVKGPPQGPRLHIDIPRVQLLIEDKEGIKQLDDKATIPVTDAEFSQAVNPQSFCTGVSLHHPALIQSTGPLIDMSDIRPGTNPVSRKNVKSAHSTRNRYSSQWTLTKCQASTPARTLTSDWRTVGSQHGVTVTESDSYSASLSQDTDKGRNSMVSTESASSTYEELARAYEHAKLEEQLQHAKFEITECFISDSSSDQMTTGTNENADSMTSMSTPSEPGICRFTASPPKPQDADRGKNVAVPIPHRANKSDYCNLPLYAKSEAFFRKADGREPCPVVPPREASIRNLARTYHPQARHLTLDPASKPLGLPHPGAPAAASTATLPQRTLAMPAPPAGTAPPAPPTPAEPPAAPSAAPPAPSTEPPRAGGPHTKMGGSRDSLLEMSTSGVGRSQKQGAGAYSKSYTLV", "length": 2111, "header": "tr|A0A5G2QYF1-1|A0A5G2QYF1_PIG Isoform 1 of Cell adhesion molecule DSCAML1 OS=Sus scrofa OX=9823 GN=DSCAML1 PE=4 SV=1 CANONICAL=A0A5G2QYF1-1" }, "locus": { "chromosome": "9", "start_pos": 45146958, "end_pos": 44785701, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090681.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090681.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069168.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069168.1" } ] } }, { "isoform_ac": "I3LMQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1/entry#I3LMQ3-1", "sequence": { "sequence": "MTGAREPRREEPPPPPSAGLRSRESGARSAGGWERAERGRGAAARPATGPPPRRIGPLYGMWLVTFLLLLDSLHKARPEDVGTSLYFVNDSLQQLPCTASGYPIPAIRWLKDGRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGTLTVIDPLHVTLTPKKLKTGIGSTVILSCTLMGSPEFTIRWYRNTELVLPGEAISIRGLSNETLLITSAQKSHSGAYQCFASRKAQTAQDFAIIVLEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRSNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMRDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEWKDVFVSSSERSFRLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQGLRANSSGEVFLTELREATWYELRMRACNSAGCGNETAQFATLDYDGSTIPPIKSAQGEGDDVKKLFTIGCPVILATLGVALLFIVRKKRKEKRLKRLRDAKSLAEMLISKNNRSFDTPVKGPPQGPRLHIDIPRVQLLIEDKEGIKQLDDKATIPVTDAEFSQAVNPQSFCTGVSLHHPALIQSTGPLIDMSDIRPGTNPVSRKNVKSAHSTRNRYSSQWTLTKCQASTPARTLTSDWRTVGSQHGVTVTESDSYSASLSQDTDKGRNSMVSTESASSTYEELARAYEHAKLEEQLQHAKFEITECFISDSSSDQMTTGTNENADSMTSMSTPSEPGICRFTASPPKPQDADRGKNVAVPIPHRANKSDYCNLPLYAKSEAFFRKADGREPCPVVPPREASIRNLARTYHPQARHLTLDPASKPLGLPHPGAPAAASTATLPQRTLAMPAPPAGTAPPAPPTPAEPPAAPSAAPPAPSTEPPRAGGPHTKMGGSRDSLLEMSTSGVGRSQKQGAGAYSKSYTLV", "length": 1901, "header": "tr|I3LMQ3-1|A0A5G2QYF1_PIG Computationally mapped isoform of Cell adhesion molecule DSCAML1 OS=Sus scrofa OX=9823 GN=DSCAML1 PE=4 SV=4 CANONICAL=A0A5G2QYF1-1" }, "locus": { "chromosome": "9", "start_pos": 45146958, "end_pos": 44785701, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026572.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026572.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025374.4", "url": "https://www.ensembl.org/id/ENSSSCP00000025374.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2049, "start_aa": "Thr", "end_pos": 2049, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2049", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 498, "start_aa": "Thr", "end_pos": 498, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr498", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LMQ3", "url": "https://www.uniprot.org/uniprotkb/I3LMQ3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-376172", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-376172", "resource": "Reactome", "description": "DSCAM interactions" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" }, { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" }, { "name": "embryonic skeletal system morphogenesis", "id": "GO:0048704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048704", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" }, { "name": "dendrite self-avoidance", "id": "GO:0070593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070593", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1142, "end_pos": 1144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1204, "end_pos": 1206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1222, "end_pos": 1224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1335, "end_pos": 1337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1405, "end_pos": 1407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1552, "end_pos": 1554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1591, "end_pos": 1593, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1621, "end_pos": 1623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1699, "end_pos": 1701, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1953, "end_pos": 1955, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" }, { "start_pos": 770, "end_pos": 772, "annotation": "n_glycosylation_sequon" }, { "start_pos": 809, "end_pos": 811, "annotation": "n_glycosylation_sequon" }, { "start_pos": 856, "end_pos": 858, "annotation": "n_glycosylation_sequon" }, { "start_pos": 869, "end_pos": 871, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" }, { "start_pos": 986, "end_pos": 988, "annotation": "n_glycosylation_sequon" }, { "start_pos": 999, "end_pos": 1001, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 947, "end_pos": 1044, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QYF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF1" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 167, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 498, 2049 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1142, "end_pos": 1144 }, { "start_pos": 1204, "end_pos": 1206 }, { "start_pos": 1222, "end_pos": 1224 }, { "start_pos": 1335, "end_pos": 1337 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 1405, "end_pos": 1407 }, { "start_pos": 1552, "end_pos": 1554 }, { "start_pos": 1591, "end_pos": 1593 }, { "start_pos": 1621, "end_pos": 1623 }, { "start_pos": 1699, "end_pos": 1701 }, { "start_pos": 1953, "end_pos": 1955 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 616, "end_pos": 618 }, { "start_pos": 726, "end_pos": 728 }, { "start_pos": 770, "end_pos": 772 }, { "start_pos": 809, "end_pos": 811 }, { "start_pos": 856, "end_pos": 858 }, { "start_pos": 869, "end_pos": 871 }, { "start_pos": 89, "end_pos": 91 }, { "start_pos": 986, "end_pos": 988 }, { "start_pos": 999, "end_pos": 1001 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYF3-1", "uniprot_ac": "A0A5G2QYF3", "uniprot_id": "A0A5G2QYF3_PIG", "mass": { "chemical_mass": 34871.0, "monoisotopic_mass": 34871.0 }, "refseq": { "ac": "XP_003358169", "name": "olfactory receptor 4D2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358169" }, "gene_names": [ { "name": "LOC100625111", "type": "recommended", "evidence": [ { "id": "A0A5G2QYF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3" } ] }, { "name": "LOC100625111", "type": "synonym", "evidence": [ { "id": "XP_003358169", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358169" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QYF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4D2-like", "type": "synonym", "evidence": [ { "id": "XP_003358169", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358169" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100625111", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3", "locus": {} } ], "crossref": [ { "id": "A0A5G2QYF3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYF3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100625111", "url": "https://www.ncbi.nlm.nih.gov/gene/100625111", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100625111", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625111", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MENCTRV", "url": "https://omabrowser.org/oma/group/MENCTRV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QYF3", "url": "https://www.orthodb.org/?gene=A0A5G2QYF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003358169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358169", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QYF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESGNLTWVSEFVFLGLSQTRELQLLLFLVVLFVYTTTVLGNLLIMVSVTSDSRLHTPMYFLLRNLALLDLSVSSVISPKMLVDLLSEKKTISYQGCMAQIFFFHFVGGGIVFFLSVMAYDRLVAISRPLHYVTIMNTQLCVGLVVASWVGGFIHSISQMALMLPLPFCGPNVLDNFYCDIPQVLRLACTDTSLLEFLIICNSGVLVLIWFLLLLISYSVILVMLRSHSGQARRKAASTCTTHIIVVSMGFIPSIYLYARPFTSFPMDKAVSISHTVMTPMLNPMIYTLRNQEMQAAMKRLVKHLVIGSRE", "length": 311, "header": "tr|A0A5G2QYF3-1|A0A5G2QYF3_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100625111 PE=3 SV=1 CANONICAL=A0A5G2QYF3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3/entry#A0A5G2QYF3-1", "sequence": { "sequence": "MESGNLTWVSEFVFLGLSQTRELQLLLFLVVLFVYTTTVLGNLLIMVSVTSDSRLHTPMYFLLRNLALLDLSVSSVISPKMLVDLLSEKKTISYQGCMAQIFFFHFVGGGIVFFLSVMAYDRLVAISRPLHYVTIMNTQLCVGLVVASWVGGFIHSISQMALMLPLPFCGPNVLDNFYCDIPQVLRLACTDTSLLEFLIICNSGVLVLIWFLLLLISYSVILVMLRSHSGQARRKAASTCTTHIIVVSMGFIPSIYLYARPFTSFPMDKAVSISHTVMTPMLNPMIYTLRNQEMQAAMKRLVKHLVIGSRE", "length": 311, "header": "tr|A0A5G2QYF3-1|A0A5G2QYF3_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100625111 PE=3 SV=1 CANONICAL=A0A5G2QYF3-1" }, "locus": { "chromosome": "12", "start_pos": 34455489, "end_pos": 34454557, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078907.1", "url": "https://www.ensembl.org/id/ENSSSCT00000078907.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069946.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069946.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100625111", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625111", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5YBF3-1", "protein_name": "Olfactory receptor", "gene_name": "Or4d10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EMENYTRVKELIFLGLTQSHEVSMVLFLFLLLVYVTTLLGNLLIMVTVTYESRLHTPMYFLLRNLSIADICFSSITAPKVLVDLLSDRKTISFNGCLTQMFFFHLIGGVDVFSLSVMALDRYVAISKPLHYVTIMSRGRCIGLIAASWVGGFAHSIVQISLLLTLPFCGPNVLDTFYCDVPQVIKLACTDIFVLELLMISNNGMLTTLWFFLLLISYMVILLLLRSHSGEGRKKAISTCTSHITVITLHFVPCIYVYARPFTALPTDKAISVTFTVISPLLNPLIYTLRNQEMKSAMRRLRKRLGPSHRIEK", "length": 312 }, "evidence": [ { "id": "A0A5G2QYF3", "url": "https://omabrowser.org/oma/group/A0A5G2QYF3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BDB3-1", "protein_name": "Olfactory receptor", "gene_name": "OR4D11B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELGNGTRVKEFIFLGLTQNQELSLVLFLFLLLVYVTTLLGNLLIMVTVTRDSRLHTPMYFLLRNLSVADICFSSITAPKVLADLLVQRKAISFNGCFTQMFFFHLIGGVDVASLSLMAFDRYVAITKPLHYVTIMSRGRCTALIMASWAGGFVHSIVQISLLLPLPFCGPNVLDTFYCDVPQVLTLACTDIFILELLMISNSGLLTTLWFVFLLVSYMVILLLIRSQAGEGRGKAISTCTAHITVVTLHFVPCIYVYARPFSTLPTDKAVSVTFTVISPLLNPLIYTLRNQEMKAAMRRLRGRLGPSDKE", "length": 311 }, "evidence": [ { "id": "A0A5G2QYF3", "url": "https://omabrowser.org/oma/group/A0A5G2QYF3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "K7N659-1", "protein_name": "Olfactory receptor", "gene_name": "Or4d10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EMENYTRVKELIFLGLTQSQEVSMVLFLFLLLVYVTTLLGNLLIMVTVTCESRLHTPMYFLLRNLSVADICFSSITAPKVLVDLLSDRKTISFNGCLTQMFFFHLIGGVDVFSLSVMALDRYVAISKPLHYVTIMSRGRCIGLIVASWVGGFAHSIVQISLLLTLPFCGPNVLDTFYCDVPQVIKLACTDIFVLELLMISNNGMLTTLWFFLLLVSYMVILLLLKSQSGEGKKKAISTCTSHITVITLHFVPCIYVYARPFTALPTDKAISVTFTVISPLLNPLIYTLRNQEMKSAMRRLRKRLGPSYWIER", "length": 312 }, "evidence": [ { "id": "A0A5G2QYF3", "url": "https://omabrowser.org/oma/group/A0A5G2QYF3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NGI6-1", "protein_name": "Olfactory receptor 4D10", "gene_name": "OR4D10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEMENCTRVKEFIFLGLTQNREVSLVLFLFLLLVYVTTLLGNLLIMVTVTCESRLHTPMYFLLHNLSIADICFSSITVPKVLVDLLSERKTISFNHCFTQMFLFHLIGGVDVFSLSVMALDRYVAISKPLHYATIMSRDHCIGLTVAAWLGGFVHSIVQISLLLPLPFCGPNVLDTFYCDVHRVLKLAHTDIFILELLMISNNGLLTTLWFFLLLVSYIVILSLPKSQAGEGRRKAISTCTSHITVVTLHFVPCIYVYARPFTALPMDKAISVTFTVISPLLNPLIYTLRNHEMKSAMRRLKRRLVPSDRK", "length": 311 }, "evidence": [ { "id": "A0A5G2QYF3", "url": "https://omabrowser.org/oma/group/A0A5G2QYF3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QYF3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QYF3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYF3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYK1-1", "uniprot_ac": "A0A5G2QYK1", "uniprot_id": "A0A5G2QYK1_PIG", "mass": { "chemical_mass": 34658.0, "monoisotopic_mass": 34658.0 }, "refseq": { "ac": "XP_003355170", "name": "olfactory receptor 10R2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355170" }, "gene_names": [ { "name": "LOC100626599", "type": "recommended", "evidence": [ { "id": "A0A5G2QYK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1" } ] }, { "name": "LOC100626599", "type": "synonym", "evidence": [ { "id": "XP_003355170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355170" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QYK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 10R2", "type": "synonym", "evidence": [ { "id": "XP_003355170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355170" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100626599", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1", "locus": {} } ], "crossref": [ { "id": "A0A5G2QYK1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626599", "url": "https://www.ncbi.nlm.nih.gov/gene/100626599", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626599", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626599", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LMSWRIC", "url": "https://omabrowser.org/oma/group/LMSWRIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QYK1", "url": "https://www.orthodb.org/?gene=A0A5G2QYK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003355170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355170", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QYK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANSSCVTEFFLLGFSSLGDLQLVLFVIFLCLYLIILSGNITIISVIRLDHSLHTPMYFFLSVLSTSEIFYTIVILPKMLVNLLSVLRTLSFVSCASQMYFFLGFAVTNCLLLGVMGYDRYAAICQPLHYPILMSWRVCGQLAATCIVNGFLISLVGTTLVFSLPFCGSNKVNHYFCDISPVIHLASAETYINQLVIFICGILVLVVPLTCICISYGFIVSTILKIPSTEGKQKAFSTCASHLIVVIVHYGCASFVYLRPSAKYTTGKDRLVTVTYTIITPLLNPMVYSLRNKDVQLAIRKMIGKTGFSVKTL", "length": 313, "header": "tr|A0A5G2QYK1-1|A0A5G2QYK1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100626599 PE=3 SV=1 CANONICAL=A0A5G2QYK1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1/entry#A0A5G2QYK1-1", "sequence": { "sequence": "MANSSCVTEFFLLGFSSLGDLQLVLFVIFLCLYLIILSGNITIISVIRLDHSLHTPMYFFLSVLSTSEIFYTIVILPKMLVNLLSVLRTLSFVSCASQMYFFLGFAVTNCLLLGVMGYDRYAAICQPLHYPILMSWRVCGQLAATCIVNGFLISLVGTTLVFSLPFCGSNKVNHYFCDISPVIHLASAETYINQLVIFICGILVLVVPLTCICISYGFIVSTILKIPSTEGKQKAFSTCASHLIVVIVHYGCASFVYLRPSAKYTTGKDRLVTVTYTIITPLLNPMVYSLRNKDVQLAIRKMIGKTGFSVKTL", "length": 313, "header": "tr|A0A5G2QYK1-1|A0A5G2QYK1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100626599 PE=3 SV=1 CANONICAL=A0A5G2QYK1-1" }, "locus": { "chromosome": "4", "start_pos": 91899160, "end_pos": 91898222, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068012.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068012.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069991.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069991.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626599", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626599", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QYK1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QYK1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYK1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYK1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYL6-1", "uniprot_ac": "A0A5G2QYL6", "uniprot_id": "A0A5G2QYL6_PIG", "mass": { "chemical_mass": 80986.0, "monoisotopic_mass": 80986.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC13", "type": "recommended", "evidence": [ { "id": "A0A5G2QYL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 13", "type": "synonym", "evidence": [ { "id": "A0A5G2QYL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CCDC13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6", "locus": { "chromosome": "13", "start_pos": 26220622, "end_pos": 26265700, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000050245", "url": "https://www.ensembl.org/id/ENSSSCG00000050245" } ] } } ], "crossref": [ { "id": "A0A5G2QYL6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYL6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050245", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050245", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR038929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31935", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31935", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31935:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31935:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QYL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAENEGSQDTLRLQFRAMQEMQHRRLQKQMEKRKEKELSLQSRVNDQKEPLEISDGLSVLQAGEQNSKTSFEQRVLEDEIQQLRDQLRETVDENGRLYKLLKERDFEIKHLKKKIEEDRFAFTGTAGAAGDVIATKIVELSKKNRVLMAESEGAKTRVRQLSNRIQELEQELQTALARLPAKGATDAGTKPLRAQMGDRILPESPEVKVLQDRLAATNLKMSDLRNQIQAVKQELRIAQKVLTSEVGEDVNIQQLLSSPGSWRGRAQQILVLQSKVRELERQLGQTRSQSIETASDELPAHPDPRKLSAQEKNLLRIRNLEREKQEGWEKLAAERDALRELEELKKKFEGVRSRNKVLSSEVKTLRSQMGTLVEKGRHDDELIDALMDQLRQLQEILGSLSLQEEKTRVSQHHLDQQLNNEAQRSSSLVAQLRAMVAEREAKVRQLELEIGQLSVQYLRNKGVGEGSSGPEVNPATTKFPNDLGLARSPASAAGDHAGRLGSSRSVTSLGHTLVESALTWPSLPSPHGPSPRFLDSPEQKGWQTQVTEFKALWQAAEVERDRLTEFVTVLQKRVESNIKLLESERKLQEERHRTVVLEQHLEKMRLEPARTSTSQRAAPRSKTGLPASNTKHNLNGSERKDLSSTQLSNVPVESQMEELTTRIAIQVEENEMLKAALDSTLRGKEEDFRMYHETLGQVKGVFLQALRQQKVDKH", "length": 714, "header": "tr|A0A5G2QYL6-1|A0A5G2QYL6_PIG Isoform 1 of Coiled-coil domain containing 13 OS=Sus scrofa OX=9823 GN=CCDC13 PE=4 SV=1 CANONICAL=A0A5G2QYL6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6/entry#A0A5G2QYL6-1", "sequence": { "sequence": "MAENEGSQDTLRLQFRAMQEMQHRRLQKQMEKRKEKELSLQSRVNDQKEPLEISDGLSVLQAGEQNSKTSFEQRVLEDEIQQLRDQLRETVDENGRLYKLLKERDFEIKHLKKKIEEDRFAFTGTAGAAGDVIATKIVELSKKNRVLMAESEGAKTRVRQLSNRIQELEQELQTALARLPAKGATDAGTKPLRAQMGDRILPESPEVKVLQDRLAATNLKMSDLRNQIQAVKQELRIAQKVLTSEVGEDVNIQQLLSSPGSWRGRAQQILVLQSKVRELERQLGQTRSQSIETASDELPAHPDPRKLSAQEKNLLRIRNLEREKQEGWEKLAAERDALRELEELKKKFEGVRSRNKVLSSEVKTLRSQMGTLVEKGRHDDELIDALMDQLRQLQEILGSLSLQEEKTRVSQHHLDQQLNNEAQRSSSLVAQLRAMVAEREAKVRQLELEIGQLSVQYLRNKGVGEGSSGPEVNPATTKFPNDLGLARSPASAAGDHAGRLGSSRSVTSLGHTLVESALTWPSLPSPHGPSPRFLDSPEQKGWQTQVTEFKALWQAAEVERDRLTEFVTVLQKRVESNIKLLESERKLQEERHRTVVLEQHLEKMRLEPARTSTSQRAAPRSKTGLPASNTKHNLNGSERKDLSSTQLSNVPVESQMEELTTRIAIQVEENEMLKAALDSTLRGKEEDFRMYHETLGQVKGVFLQALRQQKVDKH", "length": 714, "header": "tr|A0A5G2QYL6-1|A0A5G2QYL6_PIG Isoform 1 of Coiled-coil domain containing 13 OS=Sus scrofa OX=9823 GN=CCDC13 PE=4 SV=1 CANONICAL=A0A5G2QYL6-1" }, "locus": { "chromosome": "13", "start_pos": 26259758, "end_pos": 26225337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089400.3", "url": "https://www.ensembl.org/id/ENSSSCT00000089400.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070006.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070006.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6" } ], "pmid": "" }, { "name": "axonemal central pair", "id": "GO:0097540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097540", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QYL6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 714, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QYL6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYL6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 635, "end_pos": 637 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYM7-1", "uniprot_ac": "A0A5G2QYM7", "uniprot_id": "A0A5G2QYM7_PIG", "mass": { "chemical_mass": 34694.0, "monoisotopic_mass": 34694.0 }, "refseq": { "ac": "XP_003122741", "name": "olfactory receptor 5AN1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122741" }, "gene_names": [ { "name": "LOC100516243", "type": "recommended", "evidence": [ { "id": "A0A5G2QYM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7" } ] }, { "name": "LOC100516243", "type": "synonym", "evidence": [ { "id": "XP_003122741", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122741" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QYM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5AN1-like", "type": "synonym", "evidence": [ { "id": "XP_003122741", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122741" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYM7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYM7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100516243", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7", "locus": {} } ], "crossref": [ { "id": "A0A5G2QYM7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15417", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15417", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100516243", "url": "https://www.ncbi.nlm.nih.gov/gene/100516243", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516243", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516243", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CLIMLIR", "url": "https://omabrowser.org/oma/group/CLIMLIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QYM7", "url": "https://www.orthodb.org/?gene=A0A5G2QYM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003122741", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122741", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QYM7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGGDNTTDNTDFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVFSTMGLSESCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSASLSELCAMLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTSIFTVIFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSSIFVYLSSSSGGSSGLNRFASVFYTVVIPMLNPLIYSLRNKDIKDALKRLQKGKECC", "length": 312, "header": "tr|A0A5G2QYM7-1|A0A5G2QYM7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100516243 PE=3 SV=1 CANONICAL=A0A5G2QYM7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7/entry#A0A5G2QYM7-1", "sequence": { "sequence": "MTGGDNTTDNTDFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVFSTMGLSESCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSASLSELCAMLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTSIFTVIFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSSIFVYLSSSSGGSSGLNRFASVFYTVVIPMLNPLIYSLRNKDIKDALKRLQKGKECC", "length": 312, "header": "tr|A0A5G2QYM7-1|A0A5G2QYM7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100516243 PE=3 SV=1 CANONICAL=A0A5G2QYM7-1" }, "locus": { "chromosome": "AEMK02000637.1", "start_pos": 24490, "end_pos": 23555, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070612.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070612.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063324.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063324.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYM7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516243", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516243", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYM7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYM7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYM7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYM7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QYM7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QYM7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYM7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 291, "start_aa": "Trp", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 66, "end_pos": 68 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYN4-1", "uniprot_ac": "A0A5G2QYN4", "uniprot_id": "A0A5G2QYN4_PIG", "mass": { "chemical_mass": 33960.0, "monoisotopic_mass": 33960.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "L1 transposable element RRM domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QYN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN4", "locus": {} } ], "crossref": [ { "id": "A0A5G2QYN4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYN4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QYN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLRNHPQLNQQENSPKAVNNETDLCSLTDLEFKRETAKILKELREDMNSNADSVRKELENIRRSQEKPENSFAAIQMELKAVKTRMNNAEEQISHVEYRMMEITQMGQQTENQMKKHESNKRDLWDNMKWANLCIIGIPEGEEKDNGIENIFEEINAGNFPNLKDTDFKIQESHRAPNKLNPNRPTLKHIIIKIAKVNNKERILNAARQKQNVTCKGTPIRLSAAFSTETLQARREWQALKGKNIQPRILYPARISFKTKGEIKIFSNKQKLKEYSNTKPILKEILKGLL", "length": 292, "header": "tr|A0A5G2QYN4-1|A0A5G2QYN4_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QYN4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN4/entry#A0A5G2QYN4-1", "sequence": { "sequence": "MKKLRNHPQLNQQENSPKAVNNETDLCSLTDLEFKRETAKILKELREDMNSNADSVRKELENIRRSQEKPENSFAAIQMELKAVKTRMNNAEEQISHVEYRMMEITQMGQQTENQMKKHESNKRDLWDNMKWANLCIIGIPEGEEKDNGIENIFEEINAGNFPNLKDTDFKIQESHRAPNKLNPNRPTLKHIIIKIAKVNNKERILNAARQKQNVTCKGTPIRLSAAFSTETLQARREWQALKGKNIQPRILYPARISFKTKGEIKIFSNKQKLKEYSNTKPILKEILKGLL", "length": 292, "header": "tr|A0A5G2QYN4-1|A0A5G2QYN4_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QYN4-1" }, "locus": { "chromosome": "13", "start_pos": 116378259, "end_pos": 116377384, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073165.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073165.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069988.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069988.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QYN4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 292, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QYN4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYN4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN4" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 134, "end_pos": 226, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QYN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN4" }, { "id": "PF17490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element dsRBD-like", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 289, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYN5-1", "uniprot_ac": "A0A5G2QYN5", "uniprot_id": "A0A5G2QYN5_PIG", "mass": { "chemical_mass": 29504.0, "monoisotopic_mass": 29504.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "L1 transposable element RRM domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QYN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN5", "locus": {} } ], "crossref": [ { "id": "A0A5G2QYN5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYN5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044967", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044967", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QYN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSQTDLDLKREILKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEEQISDMEDRIMEITQSSQQTENRIKKLESNIRDLWDNKKRANLRIIGIPEGVEKDKGMENIFEEIIDGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARTEWQEIFKVLKGKKYAT", "length": 253, "header": "tr|A0A5G2QYN5-1|A0A5G2QYN5_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QYN5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN5/entry#A0A5G2QYN5-1", "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSQTDLDLKREILKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEEQISDMEDRIMEITQSSQQTENRIKKLESNIRDLWDNKKRANLRIIGIPEGVEKDKGMENIFEEIIDGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARTEWQEIFKVLKGKKYAT", "length": 253, "header": "tr|A0A5G2QYN5-1|A0A5G2QYN5_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QYN5-1" }, "locus": { "chromosome": "13", "start_pos": 111802169, "end_pos": 111801411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089710.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089710.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070026.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070026.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QYN5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 253, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QYN5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYN5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN5" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 227, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYS1-1", "uniprot_ac": "A0A5G2QYS1", "uniprot_id": "A0A5G2QYS1_PIG", "mass": { "chemical_mass": 25173.0, "monoisotopic_mass": 25173.0 }, "refseq": { "ac": "XP_020922789", "name": "uncharacterized protein LOC100621431 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922789" }, "gene_names": [ { "name": "LOC100621431", "type": "recommended", "evidence": [ { "id": "A0A5G2QYS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1" } ] }, { "name": "LOC100621431", "type": "synonym", "evidence": [ { "id": "XP_020922789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922789" } ] } ], "protein_names": [ { "name": "Guanine nucleotide-binding protein subunit gamma", "type": "recommended", "evidence": [ { "id": "A0A5G2QYS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100621431 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020922789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922789" } ] } ], "function": [ { "annotation": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1#function" }, { "database": "UniProtKB", "id": "RU004973", "url": "https://www.uniprot.org/uniprotkb/RU004973#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100621431", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1", "locus": {} } ], "crossref": [ { "id": "A0A5G2QYS1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045794", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045794", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00068", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00068", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100621431", "url": "https://www.ncbi.nlm.nih.gov/gene/100621431", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621431", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621431", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QYS1", "url": "https://www.orthodb.org/?gene=A0A5G2QYS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1296041", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296041", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-202040", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202040", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-392170", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-392451", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392451", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4086398", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4086398", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418597", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-428930", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-428930", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-456926", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-456926", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6814122", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6814122", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8964616", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-997272", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020922789", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922789", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QYS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPELGEPCKGKLWGLNGGHSGSPGLASLGRKNSLRAGSEVGKQRAWGRRQGKGSLQGWRVRTREMGSKPEPKGVPRGMGLMLGRGCRGPAVVAVLEAQAAGWAWNLEPMISLGVRDLGFQTICFIQRLSADQEPGGSNPILSGSGTSGLKCTLLLGRTWSLRGRMAQDLSEKELLKMEVEQLKKEVKTPRALISKTGKEIKDYVEAEAGNDPLLKGIPEDKNPFKEKGGCLIS", "length": 234, "header": "tr|A0A5G2QYS1-1|A0A5G2QYS1_PIG Isoform 1 of Guanine nucleotide-binding protein subunit gamma OS=Sus scrofa OX=9823 GN=LOC100621431 PE=3 SV=1 CANONICAL=A0A5G2QYS1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1/entry#A0A5G2QYS1-1", "sequence": { "sequence": "MEPELGEPCKGKLWGLNGGHSGSPGLASLGRKNSLRAGSEVGKQRAWGRRQGKGSLQGWRVRTREMGSKPEPKGVPRGMGLMLGRGCRGPAVVAVLEAQAAGWAWNLEPMISLGVRDLGFQTICFIQRLSADQEPGGSNPILSGSGTSGLKCTLLLGRTWSLRGRMAQDLSEKELLKMEVEQLKKEVKTPRALISKTGKEIKDYVEAEAGNDPLLKGIPEDKNPFKEKGGCLIS", "length": 234, "header": "tr|A0A5G2QYS1-1|A0A5G2QYS1_PIG Isoform 1 of Guanine nucleotide-binding protein subunit gamma OS=Sus scrofa OX=9823 GN=LOC100621431 PE=3 SV=1 CANONICAL=A0A5G2QYS1-1" }, "locus": { "chromosome": "12", "start_pos": 25424538, "end_pos": 25421426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071457.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071457.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070061.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070061.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621431", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621431", "resource": "KEGG Pathway" }, { "id": "R-SSC-1296041", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296041", "resource": "Reactome", "description": "Activation of G protein gated Potassium channels" }, { "id": "R-SSC-202040", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202040", "resource": "Reactome", "description": "G-protein activation" }, { "id": "R-SSC-392170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392170", "resource": "Reactome", "description": "ADP signalling through P2Y purinoceptor 12" }, { "id": "R-SSC-392451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392451", "resource": "Reactome", "description": "G beta:gamma signalling through PI3Kgamma" }, { "id": "R-SSC-4086398", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4086398", "resource": "Reactome", "description": "Ca2+ pathway" }, { "id": "R-SSC-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-SSC-418597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418597", "resource": "Reactome", "description": "G alpha (z) signalling events" }, { "id": "R-SSC-428930", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-428930", "resource": "Reactome", "description": "Thromboxane signalling through TP receptor" }, { "id": "R-SSC-456926", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-456926", "resource": "Reactome", "description": "Thrombin signalling through proteinase activated receptors (PARs)" }, { "id": "R-SSC-6814122", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6814122", "resource": "Reactome", "description": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" }, { "id": "R-SSC-8964616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964616", "resource": "Reactome", "description": "G beta:gamma signalling through CDC42" }, { "id": "R-SSC-997272", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "resource": "Reactome", "description": "Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G-protein beta-subunit binding", "id": "GO:0031681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031681", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "heterotrimeric G-protein complex", "id": "GO:0005834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005834", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QYS1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 234, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QYS1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYS1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS1" }, { "id": "PS50058", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50058" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G protein gamma", "eco_id": "ECO_0000259", "start_pos": 166, "end_pos": 234, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QYT7-1", "uniprot_ac": "A0A5G2QYT7", "uniprot_id": "A0A5G2QYT7_PIG", "mass": { "chemical_mass": 15426.0, "monoisotopic_mass": 15426.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "LITAF domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QYT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7", "locus": {} } ], "crossref": [ { "id": "A0A5G2QYT7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYT7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000047239", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000047239", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23292:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23292:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10601", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10601", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QYT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FPC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGASRDQHLAARSLEPNTAPMPLLEQRTPWVPTGSHPQGPPPHPPLPPRPGPPLPMHSSPGPFPSGLQLLSPDPTPSVCPYCGTHIITVTKAVPGTLTWILCTGICMAGCIMGCCLIPFCVDSLMDVLHTCPVCQQELFCYKRL", "length": 144, "header": "tr|A0A5G2QYT7-1|A0A5G2QYT7_PIG Isoform 1 of LITAF domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QYT7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7/entry#A0A5G2QYT7-1", "sequence": { "sequence": "MGASRDQHLAARSLEPNTAPMPLLEQRTPWVPTGSHPQGPPPHPPLPPRPGPPLPMHSSPGPFPSGLQLLSPDPTPSVCPYCGTHIITVTKAVPGTLTWILCTGICMAGCIMGCCLIPFCVDSLMDVLHTCPVCQQELFCYKRL", "length": 144, "header": "tr|A0A5G2QYT7-1|A0A5G2QYT7_PIG Isoform 1 of LITAF domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QYT7-1" }, "locus": { "chromosome": "3", "start_pos": 33819887, "end_pos": 33815029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090417.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090417.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069308.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069308.1" } ] } }, { "isoform_ac": "A0A8W4FPC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7/entry#A0A8W4FPC4-1", "sequence": { "sequence": "MHSSPGPFPSGLQLLSPDPTPSVCPYCGTHIITVTKAVPGTLTWILCTGICMAGCIMGCCLIPFCVDSLMDVLHTCPVCQQELFCYKRL", "length": 89, "header": "tr|A0A8W4FPC4-1|A0A5G2QYT7_PIG Computationally mapped isoform of LITAF domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QYT7-1" }, "locus": { "chromosome": "3", "start_pos": 33816822, "end_pos": 33815029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104662.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104662.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081038.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081038.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 75, "start_aa": "Thr", "end_pos": 75, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr75", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPC4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7" } ], "pmid": "" }, { "name": "cytoplasmic side of lysosomal membrane", "id": "GO:0098574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098574", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7" } ], "pmid": "" }, { "name": "cytoplasmic side of late endosome membrane", "id": "GO:0098560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098560", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QYT7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 144, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QYT7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QYT7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QYT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYT7" }, { "id": "PS51837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LITAF", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 143, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 75 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZ50-1", "uniprot_ac": "A0A5G2QZ50", "uniprot_id": "A0A5G2QZ50_PIG", "mass": { "chemical_mass": 35086.0, "monoisotopic_mass": 35086.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110259076", "type": "recommended", "evidence": [ { "id": "A0A5G2QZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ50", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ50", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259076", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50", "locus": {} } ], "crossref": [ { "id": "A0A5G2QZ50", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZ50", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050937", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050937", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PRCFFLA", "url": "https://omabrowser.org/oma/group/PRCFFLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QZ50", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ50-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENRNNVTEFVLLGLTENPKMQNIIFVVFFVIYIFTVVGNMLIVVTITSSPLLESPMYYFLAYLSFIDACYSSVNTPKLIRDSLHEKKTILFNGCMTQIFGEHFFGGAEVILLTVMAFDRYVAICKPLHYTTIMNRRVCHLLMGVSWMGGFLHGFIQILFIFRLPFCGPNIIDHFMCDLNPLLNLACIDTHILGLFVAANSGFLCMLNFLLLIGSYVVILHSLRTKTLEARQKALSTCVSHIIVVVLFFVPCIFVYMRPAAILPIDKAVAVFYTMITPMLNPLIYTLRNAQMKNAIRKLCSWQAISSDK", "length": 309, "header": "tr|A0A5G2QZ50-1|A0A5G2QZ50_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259076 PE=3 SV=1 CANONICAL=A0A5G2QZ50-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZ50-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50/entry#A0A5G2QZ50-1", "sequence": { "sequence": "MENRNNVTEFVLLGLTENPKMQNIIFVVFFVIYIFTVVGNMLIVVTITSSPLLESPMYYFLAYLSFIDACYSSVNTPKLIRDSLHEKKTILFNGCMTQIFGEHFFGGAEVILLTVMAFDRYVAICKPLHYTTIMNRRVCHLLMGVSWMGGFLHGFIQILFIFRLPFCGPNIIDHFMCDLNPLLNLACIDTHILGLFVAANSGFLCMLNFLLLIGSYVVILHSLRTKTLEARQKALSTCVSHIIVVVLFFVPCIFVYMRPAAILPIDKAVAVFYTMITPMLNPLIYTLRNAQMKNAIRKLCSWQAISSDK", "length": 309, "header": "tr|A0A5G2QZ50-1|A0A5G2QZ50_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259076 PE=3 SV=1 CANONICAL=A0A5G2QZ50-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 260916, "end_pos": 259990, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070403.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070403.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063515.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063515.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ50", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ50", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ50", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ50", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZ50-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZ50-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZ50" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ50" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZ71-1", "uniprot_ac": "A0A5G2QZ71", "uniprot_id": "A0A5G2QZ71_PIG", "mass": { "chemical_mass": 38459.0, "monoisotopic_mass": 38459.0 }, "refseq": {}, "gene_names": [ { "name": "NSUN3", "type": "recommended", "evidence": [ { "id": "A0A5G2QZ71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71" } ] } ], "protein_names": [ { "name": "NOP2/Sun RNA methyltransferase 3", "type": "synonym", "evidence": [ { "id": "A0A5G2QZ71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NSUN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71", "locus": { "chromosome": "13", "start_pos": 165765502, "end_pos": 165823171, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027432", "url": "https://www.ensembl.org/id/ENSSSCG00000027432" } ] } } ], "crossref": [ { "id": "A0A5G2QZ71", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZ71", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000027432", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027432", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22808", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22808", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22808:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22808:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QZ71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ71-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTRLKAKSERKLAKQICKVVLDHFEKQYSRELGDAWNTVRDILTSPSCWQYAVLLNRFNYPFELEKDLHLKGYHSLFQGSLPYNPKSMKCYLSRTPHRMPSERHQIGNLKKFYLLNAASLLPVLALELRHGEKILDLCAAPGGKSIALLQCAYPGYLHCNEYDSLRLRWLRQTLESFIPQPLVNVIKVSELDGREMGDAQPETFDKVLVDAPCSNDRSWLFSSDSQKAAYRISQRRNLPVLQIELLRSAIKALRPGGLLVYSTCTLSKAENQDVISEVLNSCNNIMPVDIKEMARACSQDFTFAPTGQECGLLVIPDKGKAWGPMYVAKLKKSQTTNC", "length": 339, "header": "tr|A0A5G2QZ71-1|A0A5G2QZ71_PIG Isoform 1 of NOP2/Sun RNA methyltransferase 3 OS=Sus scrofa OX=9823 GN=NSUN3 PE=3 SV=1 CANONICAL=A0A5G2QZ71-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZ71-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71/entry#A0A5G2QZ71-1", "sequence": { "sequence": "MLTRLKAKSERKLAKQICKVVLDHFEKQYSRELGDAWNTVRDILTSPSCWQYAVLLNRFNYPFELEKDLHLKGYHSLFQGSLPYNPKSMKCYLSRTPHRMPSERHQIGNLKKFYLLNAASLLPVLALELRHGEKILDLCAAPGGKSIALLQCAYPGYLHCNEYDSLRLRWLRQTLESFIPQPLVNVIKVSELDGREMGDAQPETFDKVLVDAPCSNDRSWLFSSDSQKAAYRISQRRNLPVLQIELLRSAIKALRPGGLLVYSTCTLSKAENQDVISEVLNSCNNIMPVDIKEMARACSQDFTFAPTGQECGLLVIPDKGKAWGPMYVAKLKKSQTTNC", "length": 339, "header": "tr|A0A5G2QZ71-1|A0A5G2QZ71_PIG Isoform 1 of NOP2/Sun RNA methyltransferase 3 OS=Sus scrofa OX=9823 GN=NSUN3 PE=3 SV=1 CANONICAL=A0A5G2QZ71-1" }, "locus": { "chromosome": "13", "start_pos": 165823060, "end_pos": 165765505, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072951.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072951.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063535.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063535.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "rRNA methylation", "id": "GO:0031167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031167", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71" } ], "pmid": "" }, { "name": "regulation of mitochondrial translation", "id": "GO:0070129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070129", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71" } ], "pmid": "" }, { "name": "tRNA wobble base cytosine methylation", "id": "GO:0002127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002127", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "tRNA (cytidine-5-)-methyltransferase activity", "id": "GO:0016428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016428", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZ71-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 339, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZ71-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZ71" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZ71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ71" }, { "id": "PS51686", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51686" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM-dependent MTase RsmB/NOP-type", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 334, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZ82-1", "uniprot_ac": "A0A5G2QZ82", "uniprot_id": "A0A5G2QZ82_PIG", "mass": { "chemical_mass": 39426.0, "monoisotopic_mass": 39426.0 }, "refseq": {}, "gene_names": [ { "name": "IFT46", "type": "recommended", "evidence": [ { "id": "A0A5G2QZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82" } ] } ], "protein_names": [ { "name": "Intraflagellar transport protein 46 homolog", "type": "recommended", "evidence": [ { "id": "A0A5G2QZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IFT46", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82", "locus": { "chromosome": "9", "start_pos": 45844619, "end_pos": 45861879, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000029649", "url": "https://www.ensembl.org/id/ENSSSCG00000029649" } ] } } ], "crossref": [ { "id": "A0A5G2QZ82", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZ82", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000029649", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000029649", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR022088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13376:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13376:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QEQ5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QEQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFM8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ82-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9A5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9A5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FHP8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FHP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LJ92", "url": "https://www.uniprot.org/uniprotkb/I3LJ92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LJ92-1", "url": "https://www.uniprot.org/uniprotkb/I3LJ92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADNSSDECEEENNKILSEDLPQPPGPRGKDIDRVPIASKYHQTSHELERVGWFVENQKLRKEKKKTSQLTPQRGFSENDDDDDDDDSSETDSDDDEEEHRAPLEGAYDPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTKQSDPTVLSLWLTENSKQHNVTQHMKVKSLEDAEKNPKAIDTWIESISELHRSKAPATVHYTRPMPDIDTLMQEWSPEFEELLGKVSLPTAEIDCSLEGYIDMICAILDIPIYKSRIQSLHLLFSLYSEFKNSQHFKALAEGKKAFTPPSNSTSQAGDAETLTFS", "length": 348, "header": "tr|A0A5G2QZ82-1|A0A5G2QZ82_PIG Isoform 1 of Intraflagellar transport protein 46 homolog OS=Sus scrofa OX=9823 GN=IFT46 PE=1 SV=2 CANONICAL=A0A5G2QZ82-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QEQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82/entry#A0A5G2QEQ5-1", "sequence": { "sequence": "LSVGSETQCKEFSFSGSTASQSPVMSPALSETLVDSEVIEPNFPIPRAYDPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTKQSDPTVLSLWLTENSKQHNVTQHMKVKSLEDAEKNPKAIDTWIESISELHRSKAPATVHYTRPMPDIDTLMQEWSPEFEELLGKVSLPTAEIDCSLEGYIDMICAILDIPIYKSRIQSLHLLFSLYSEFKNSQHFKALAEGKKAFTPPSNSTSQAGDAETLTFS", "length": 289, "header": "tr|A0A5G2QEQ5-1|A0A5G2QEQ5_PIG Computationally mapped isoform of Intraflagellar transport protein 46 homolog OS=Sus scrofa OX=9823 GN=IFT46 PE=1 SV=2 CANONICAL=A0A5G2QZ82-1" }, "locus": { "chromosome": "9", "start_pos": 45854457, "end_pos": 45845172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072914.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072914.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062679.2", "url": "https://www.ensembl.org/id/ENSSSCP00000062679.2" } ] } }, { "isoform_ac": "A0A5G2QFM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82/entry#A0A5G2QFM8-1", "sequence": { "sequence": "TDSEGLQTKIIENQTYDERLEINDSEEVASIYTPPSRHKEKKKTSQLTPQRGFSENDDDDDDDDSSETDSDDDEEEHRAPLEGAYDPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTKQSDPTVLSLWLTENSKQHNVTQHMKVKSLEDAEKNPKAIDTWIESISELHRSKAPATVHYTRPMPDIDTLMQEWSPEFEELLGKVSLPTAEIDCSLEGYIDMICAILDIPIYKSRIQSLHLLFSLYSEFKNSQHFKALAEGKKAFTPPSNSTSQAGDAETLTFS", "length": 325, "header": "tr|A0A5G2QFM8-1|A0A5G2QFM8_PIG Computationally mapped isoform of Intraflagellar transport protein 46 homolog OS=Sus scrofa OX=9823 GN=IFT46 PE=1 SV=2 CANONICAL=A0A5G2QZ82-1" }, "locus": { "chromosome": "9", "start_pos": 45861714, "end_pos": 45845172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077311.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077311.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060839.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060839.2" } ] } }, { "isoform_ac": "A0A5G2QZ82-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82/entry#A0A5G2QZ82-1", "sequence": { "sequence": "MADNSSDECEEENNKILSEDLPQPPGPRGKDIDRVPIASKYHQTSHELERVGWFVENQKLRKEKKKTSQLTPQRGFSENDDDDDDDDSSETDSDDDEEEHRAPLEGAYDPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTKQSDPTVLSLWLTENSKQHNVTQHMKVKSLEDAEKNPKAIDTWIESISELHRSKAPATVHYTRPMPDIDTLMQEWSPEFEELLGKVSLPTAEIDCSLEGYIDMICAILDIPIYKSRIQSLHLLFSLYSEFKNSQHFKALAEGKKAFTPPSNSTSQAGDAETLTFS", "length": 348, "header": "tr|A0A5G2QZ82-1|A0A5G2QZ82_PIG Isoform 1 of Intraflagellar transport protein 46 homolog OS=Sus scrofa OX=9823 GN=IFT46 PE=1 SV=2 CANONICAL=A0A5G2QZ82-1" }, "locus": { "chromosome": "9", "start_pos": 45857348, "end_pos": 45845172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076657.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076657.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063545.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063545.2" } ] } }, { "isoform_ac": "A0A5G2R9A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82/entry#A0A5G2R9A5-1", "sequence": { "sequence": "NADQSSDTGLMEKKKTSQLTPQRGFSENDDDDDDDDSSETDSDDDEEEHRAPLEGAYDPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTKQSDPTVLSLWLTENSKQHNVTQHMKVKSLEDAEKNPKAIDTWIESISELHRSKAPATVHYTRPMPDIDTLMQEWSPEFEELLGKVSLPTAEIDCSLEGYIDMICAILDIPIYKSRIQSLHLLFSLYSEFKNSQHFKALAEGKKAFTPPSNSTSQAGDAETLTFS", "length": 297, "header": "tr|A0A5G2R9A5-1|A0A5G2R9A5_PIG Computationally mapped isoform of Intraflagellar transport protein 46 homolog OS=Sus scrofa OX=9823 GN=IFT46 PE=1 SV=1 CANONICAL=A0A5G2QZ82-1" }, "locus": { "chromosome": "9", "start_pos": 45855279, "end_pos": 45845172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082595.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082595.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070704.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070704.1" } ] } }, { "isoform_ac": "A0A8W4FHP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82/entry#A0A8W4FHP8-1", "sequence": { "sequence": "EKKKTSQLTPQRGFSENDDDDDDDDSSETDSDDDEEEHRAPLEGAYDPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTKQSDPTVLSLWLTENSKQHNVTQHMKVKSLEDAEKNPKAIDTWIESISELHRSKAPATVHYTRPMPDIDTLMQEWSPEFEELLGKVSLPTAEIDCSLEGYIDMICAILDIPIYKSRIQSLHLLFSLYSEFKNSQHFKALAEGKKAFTPPSNSTSQAGDAETLTFS", "length": 286, "header": "tr|A0A8W4FHP8-1|A0A5G2QZ82_PIG Computationally mapped isoform of Intraflagellar transport protein 46 homolog OS=Sus scrofa OX=9823 GN=IFT46 PE=1 SV=1 CANONICAL=A0A5G2QZ82-1" }, "locus": { "chromosome": "9", "start_pos": 45854700, "end_pos": 45845172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103773.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103773.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078845.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078845.1" } ] } }, { "isoform_ac": "I3LJ92-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82/entry#I3LJ92-1", "sequence": { "sequence": "SMHNKSVLCFEENPPGPRGKDIDRVPILERVGWFVENQKLRKEKKKTSQLTPQRGFSENDDDDDDDDSSETDSDDDEEEHRAPLEGAYDPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTKQSDPTVLSLWLTENSKQHNVTQHMKVKSLEDAEKNPKAIDTWIESISELHRSKAPATVHYTRPMPDIDTLMQEWSPEFEELLGKVSLPTAEIDCSLEGYIDMICGK", "length": 270, "header": "tr|I3LJ92-1|A0A5G2QZ82_PIG Computationally mapped isoform of Intraflagellar transport protein 46 homolog OS=Sus scrofa OX=9823 GN=IFT46 PE=1 SV=4 CANONICAL=A0A5G2QZ82-1" }, "locus": { "chromosome": "9", "start_pos": 45856173, "end_pos": 45846084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027542.4", "url": "https://www.ensembl.org/id/ENSSSCT00000027542.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024150.4", "url": "https://www.ensembl.org/id/ENSSSCP00000024150.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FHP8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHP8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620924", "resource": "Reactome", "description": "Intraflagellar transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82" } ], "pmid": "" }, { "name": "intraciliary transport particle A", "id": "GO:0030991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030991", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82" } ], "pmid": "" }, { "name": "intraciliary transport particle B", "id": "GO:0030992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82" } ], "pmid": "" }, { "name": "intraciliary transport", "id": "GO:0042073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZ82-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 348, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZ82-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZ82" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZ84-1", "uniprot_ac": "A0A5G2QZ84", "uniprot_id": "A0A5G2QZ84_PIG", "mass": { "chemical_mass": 42968.0, "monoisotopic_mass": 42968.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QZ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ84/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ84" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ84", "locus": {} } ], "crossref": [ { "id": "A0A5G2QZ84", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZ84", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000039954", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000039954", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QZ84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ84-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQVEEKAFQALSEGSLTKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHVVNFITTTTSISQYRCISNFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQTSSVSEHHPNYH", "length": 383, "header": "tr|A0A5G2QZ84-1|A0A5G2QZ84_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QZ84-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZ84-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ84/entry#A0A5G2QZ84-1", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQVEEKAFQALSEGSLTKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHVVNFITTTTSISQYRCISNFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQTSSVSEHHPNYH", "length": 383, "header": "tr|A0A5G2QZ84-1|A0A5G2QZ84_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2QZ84-1" }, "locus": { "chromosome": "Y", "start_pos": 22861549, "end_pos": 22859921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085659.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085659.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069453.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069453.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ84" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ84" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZ84-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 383, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZ84-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZ84" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ84" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 333, "end_pos": 335 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2QZD2-1", "uniprot_ac": "A0A5G2QZD2", "uniprot_id": "A0A5G2QZD2_PIG", "mass": { "chemical_mass": 34674.0, "monoisotopic_mass": 34674.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QZD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZD2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZD2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2", "locus": {} } ], "crossref": [ { "id": "A0A5G2QZD2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000048412", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000048412", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QZD2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNMRNDTEELKEFLLLGIPQTEGLEPVLFVIFSAIYLFTLLGNLLIIVAITSSSTLRTPMYFFLGLLSILDILFPSVTCPKMLFYLSGRSRAISYEGCAAQLFFYHFLGSTEGCLYSVMAYDRFVAICHPLRYMLIMRPGVCVGLVMAALLVDCLHATILMSLTFQLPYCGPNQVAYFFCDIPAVLPLACADSSLAQRVGSTNVGFLVLLFWFSVCASYTRIGIAILRIRSAEGKQKAFSTCSAHLTAILCAYGPVIIIYLQPTPNALVGAMVQILNNIVSPMLNSLIYSLRNKEVKSSLKRVFHKVVFTALE", "length": 313, "header": "tr|A0A5G2QZD2-1|A0A5G2QZD2_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2QZD2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2/entry#A0A5G2QZD2-1", "sequence": { "sequence": "MNMRNDTEELKEFLLLGIPQTEGLEPVLFVIFSAIYLFTLLGNLLIIVAITSSSTLRTPMYFFLGLLSILDILFPSVTCPKMLFYLSGRSRAISYEGCAAQLFFYHFLGSTEGCLYSVMAYDRFVAICHPLRYMLIMRPGVCVGLVMAALLVDCLHATILMSLTFQLPYCGPNQVAYFFCDIPAVLPLACADSSLAQRVGSTNVGFLVLLFWFSVCASYTRIGIAILRIRSAEGKQKAFSTCSAHLTAILCAYGPVIIIYLQPTPNALVGAMVQILNNIVSPMLNSLIYSLRNKEVKSSLKRVFHKVVFTALE", "length": 313, "header": "tr|A0A5G2QZD2-1|A0A5G2QZD2_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2QZD2-1" }, "locus": { "chromosome": "9", "start_pos": 51044380, "end_pos": 51043189, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074510.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074510.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067308.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067308.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZD2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZD2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZD2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZD2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZD2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZD2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZD2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZD2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZD2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZG8-1", "uniprot_ac": "A0A5G2QZG8", "uniprot_id": "A0A5G2QZG8_PIG", "mass": { "chemical_mass": 15028.0, "monoisotopic_mass": 15028.0 }, "refseq": {}, "gene_names": [ { "name": "CENPX", "type": "recommended", "evidence": [ { "id": "A0A5G2QZG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8" } ] } ], "protein_names": [ { "name": "Centromere protein X", "type": "recommended", "evidence": [ { "id": "A0A5G2QZG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CENPX", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QZG8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000049515", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000049515", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22921", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22921", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR018552", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018552", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR28680", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28680", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28680:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28680:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-606279", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-606279", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QZG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPFASLGTPLSQLVLAPLVVRVSRCSSCSPGGSLALSALPWSLGSSGAAGPSGLSWWDQQVAPSSRAHSGRELVSKLLHLHFKDDKTKVSGDALQLTAELLKVFVVEAAVRSVRQAQAEDLTRVDVDQLEKVLPQLLLDF", "length": 141, "header": "tr|A0A5G2QZG8-1|A0A5G2QZG8_PIG Isoform 1 of Centromere protein X OS=Sus scrofa OX=9823 GN=CENPX PE=3 SV=2 CANONICAL=A0A5G2QZG8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8/entry#A0A5G2QZG8-1", "sequence": { "sequence": "MLPFASLGTPLSQLVLAPLVVRVSRCSSCSPGGSLALSALPWSLGSSGAAGPSGLSWWDQQVAPSSRAHSGRELVSKLLHLHFKDDKTKVSGDALQLTAELLKVFVVEAAVRSVRQAQAEDLTRVDVDQLEKVLPQLLLDF", "length": 141, "header": "tr|A0A5G2QZG8-1|A0A5G2QZG8_PIG Isoform 1 of Centromere protein X OS=Sus scrofa OX=9823 GN=CENPX PE=3 SV=2 CANONICAL=A0A5G2QZG8-1" }, "locus": { "chromosome": "12", "start_pos": 994261, "end_pos": 992440, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072327.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072327.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067343.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067343.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-606279", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-606279", "resource": "Reactome", "description": "Deposition of new CENPA-containing nucleosomes at the centromere" }, { "id": "R-SSC-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" }, { "id": "R-SSC-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "resolution of meiotic recombination intermediates", "id": "GO:0000712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000712", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8" } ], "pmid": "" }, { "name": "kinetochore assembly", "id": "GO:0051382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051382", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Fanconi anaemia nuclear complex", "id": "GO:0043240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043240", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8" } ], "pmid": "" }, { "name": "FANCM-MHF complex", "id": "GO:0071821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071821", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZG8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 141, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZG8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZG8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZH3-1", "uniprot_ac": "A0A5G2QZH3", "uniprot_id": "A0A5G2QZH3_PIG", "mass": { "chemical_mass": 39518.0, "monoisotopic_mass": 39518.0 }, "refseq": {}, "gene_names": [ { "name": "DMRT1", "type": "recommended", "evidence": [ { "id": "A0A5G2QZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ] } ], "protein_names": [ { "name": "Doublesex and mab-3 related transcription factor 1", "type": "synonym", "evidence": [ { "id": "A0A5G2QZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DMRT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3", "locus": { "chromosome": "1", "start_pos": 220841488, "end_pos": 220953442, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005236", "url": "https://www.ensembl.org/id/ENSSSCG00000005236" } ] } } ], "crossref": [ { "id": "A0A5G2QZH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005236", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005236", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CLMTECS", "url": "https://omabrowser.org/oma/group/CLMTECS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12322:SF70", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12322:SF70", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00751", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00751", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12374", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12374", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJG1", "url": "https://www.uniprot.org/uniprotkb/F1SJG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJG1-1", "url": "https://www.uniprot.org/uniprotkb/F1SJG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNDDAYSKPSAPSEAPHAPGAPPQGKAGGFSKALLGTSGGGGSGGSSGGGSGASGMSAASNKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENHGSNPCLMTESSSSSQPPPPPPAASTPTTAAPEGRMVIQDIPAVTSRGHVENAPDLVSDSTYYSSFYQPSLFPYYNNLYNYPQYSMALAADSSSGDVGSPLGGSPVKNSLRSLPAPYVPGQTGNQWQMKNSETRHAVSSQYRMHSYYPPPSYLGQSVSQIFTFEDGPSYSEAKASVFSPPSSQDSGLVSLSSSSPISNESTKGVLECESASEPSSFAVTPVIEDDESKT", "length": 375, "header": "tr|A0A5G2QZH3-1|A0A5G2QZH3_PIG Isoform 1 of Doublesex and mab-3 related transcription factor 1 OS=Sus scrofa OX=9823 GN=DMRT1 PE=3 SV=1 CANONICAL=A0A5G2QZH3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3/entry#A0A5G2QZH3-1", "sequence": { "sequence": "MPNDDAYSKPSAPSEAPHAPGAPPQGKAGGFSKALLGTSGGGGSGGSSGGGSGASGMSAASNKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENHGSNPCLMTESSSSSQPPPPPPAASTPTTAAPEGRMVIQDIPAVTSRGHVENAPDLVSDSTYYSSFYQPSLFPYYNNLYNYPQYSMALAADSSSGDVGSPLGGSPVKNSLRSLPAPYVPGQTGNQWQMKNSETRHAVSSQYRMHSYYPPPSYLGQSVSQIFTFEDGPSYSEAKASVFSPPSSQDSGLVSLSSSSPISNESTKGVLECESASEPSSFAVTPVIEDDESKT", "length": 375, "header": "tr|A0A5G2QZH3-1|A0A5G2QZH3_PIG Isoform 1 of Doublesex and mab-3 related transcription factor 1 OS=Sus scrofa OX=9823 GN=DMRT1 PE=3 SV=1 CANONICAL=A0A5G2QZH3-1" }, "locus": { "chromosome": "1", "start_pos": 220953335, "end_pos": 220841889, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082212.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082212.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067348.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067348.1" } ] } }, { "isoform_ac": "F1SJG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3/entry#F1SJG1-1", "sequence": { "sequence": "MPNDDAYSKPSAPSEAPHAPGAPPQGKAGGFSKALLGTSGGGGSGGSSGGGSGASGMSAASNKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENHGSNPCLMTESSSSSQPPPPPPAASTPTTAAPEGRMVIQDIPAVTSRGHVENAPDLVSDSTYYSSFYQPSLFPYYNNLYNYPQYSMALAADSSSGDVGSPLGGSPVKNSLRSLPAPYVPGQTGNQWQMKNSETRHAVSSQYRMHSYYPPPSYLGQSVSQIFTFEDGPSYSEAKASVFSPPSSQDSGLVSLSSSSPISNESTKGVLECESASEPSSFAVTPVIEDDE", "length": 372, "header": "tr|F1SJG1-1|F1SJG1_PIG Computationally mapped isoform of Doublesex and mab-3 related transcription factor 1 OS=Sus scrofa OX=9823 GN=DMRT1 PE=3 SV=3 CANONICAL=A0A5G2QZH3-1" }, "locus": { "chromosome": "1", "start_pos": 220953335, "end_pos": 220842468, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005770.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005770.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005628.3", "url": "https://www.ensembl.org/id/ENSSSCP00000005628.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q925A6-1", "protein_name": "Doublesex and mab-3 related transcription factor 1", "gene_name": "Dmrt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPNDDAFGKPSAPTEVPHAPGAPPQGKAGGYSKATGAMAGAAGGSSAGGSGGASGSGPSGLGSGSKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCSLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENSASNPCLMAESSSSAQPPPASTPTPTVSEGRMVIQDIPAVTSRGHMENAPDLMSDPAYYSSFYQPSLFPYYNNLYNYPQYSMALSAESSSGDVGNPLGGSPVKNSLRSLPAPYVPAQTGNQWQMKTSEGRHPVSSQYRMHSYYGPPSYLGQSMSQIFTFEEGPSYSEAKASVFSPPSSQDSGLVSLSSSSPMSNESTKGVLECESASSEPSSYAVNQVLEEDEDE", "length": 374 }, "evidence": [ { "id": "A0A5G2QZH3", "url": "https://omabrowser.org/oma/group/A0A5G2QZH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9QZ59-1", "protein_name": "Doublesex- and mab-3-related transcription factor 1", "gene_name": "Dmrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPNDDTFGKPSTPTEVPHAPGAPPQGKAGGYSKAAGAMAGAAGGSGAGGSGGASGSGPSGLGSGSKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCSLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENNASNPCLMAENSSSAQPPPASTPTPAASEGRMVIQDIPAVTSRGHMENTSDLVSDPAYYSSFYQPSLFPYYNNLYNYPQYSMALSAESSSGEVGNSLGGSPVKNSLRSLPAPYVPAQTGNQWQMKTSESRHPVSSQYRMHSYYGPPSYLGQSMSQIFTFEEGPSYSEAKASVFSPPSSQDSGLVSLSSSSPMSNESSKGVLECESASSEPSSYAVNQVLEEDEDE", "length": 374 }, "evidence": [ { "id": "A0A5G2QZH3", "url": "https://omabrowser.org/oma/group/A0A5G2QZH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5R6-1", "protein_name": "Doublesex- and mab-3-related transcription factor 1", "gene_name": "DMRT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPNDEAFSKPSTPSEAPHAPGVPPQGRAGGFGKASGALVGAASGSSAGGSSRGGGSGSGASDLGAGSKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENNGSNPCLMTECSGTSQPPPASVPTTAASEGRMVIQDIPAVTSRGHVENTPDLVSDSTYYSSFYQPSLFPYYNNLYNCPQYSMALAADSASGEVGNPLGGSPVKNSLRGLPGPYVPGQTGNQWQMKNMENRHAMSSQYRMHSYYPPPSYLGQSVPQFFTFEDAPSYPEARASVFSPPSSQDSGLVSLSSSSPISNKSTKAVLECEPASEPSSFTVTPVIEEDE", "length": 373 }, "evidence": [ { "id": "A0A5G2QZH3", "url": "https://omabrowser.org/oma/group/A0A5G2QZH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "male sex differentiation", "id": "GO:0046661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046661", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "adult locomotory behavior", "id": "GO:0008344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008344", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "sex differentiation", "id": "GO:0007548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007548", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "positive regulation of mitotic nuclear division", "id": "GO:0045840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045840", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "male germ cell proliferation", "id": "GO:0002176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002176", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "male sex determination", "id": "GO:0030238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030238", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "negative regulation of meiotic nuclear division", "id": "GO:0045835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045835", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZH3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 375, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZH3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZH3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZH3" }, { "id": "PS50809", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50809" }, { "id": "PRU00070", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00070" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DM", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 118, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 344, "end_pos": 346 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZI2-1", "uniprot_ac": "A0A5G2QZI2", "uniprot_id": "A0A5G2QZI2_PIG", "mass": { "chemical_mass": 27066.0, "monoisotopic_mass": 27066.0 }, "refseq": {}, "gene_names": [ { "name": "APOOL", "type": "recommended", "evidence": [ { "id": "A0A5G2QZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2" } ] } ], "protein_names": [ { "name": "MICOS complex subunit", "type": "recommended", "evidence": [ { "id": "A0A5G2QZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.", "evidence": [ { "database": "UniProtKB", "id": "K7GP05", "url": "https://www.uniprot.org/uniprotkb/K7GP05#function" }, { "database": "UniProtKB", "id": "RU363021", "url": "https://www.uniprot.org/uniprotkb/RU363021#function" }, { "database": "UniProtKB", "id": "K7GNC6", "url": "https://www.uniprot.org/uniprotkb/K7GNC6#function" }, { "database": "UniProtKB", "id": "F1S1Q7", "url": "https://www.uniprot.org/uniprotkb/F1S1Q7#function" }, { "database": "UniProtKB", "id": "A0A5G2QZI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2#function" }, { "database": "UniProtKB", "id": "A0A5G2R976", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R976#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "APOOL", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2", "locus": { "chromosome": "X", "start_pos": 68355006, "end_pos": 68281869, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012459", "url": "https://www.ensembl.org/id/ENSSSCG00000012459" } ] } } ], "crossref": [ { "id": "A0A5G2QZI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012459", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012459", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSSSCG00000023546", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000023546", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100153260", "url": "https://www.ncbi.nlm.nih.gov/gene/100153260", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019166", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019166", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QVTKWAA", "url": "https://omabrowser.org/oma/group/QVTKWAA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S1Q7", "url": "https://www.orthodb.org/?gene=F1S1Q7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14564", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14564", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09769", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09769", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QZI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R976", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R976", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R976-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R976-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1Q7", "url": "https://www.uniprot.org/uniprotkb/F1S1Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1Q7-1", "url": "https://www.uniprot.org/uniprotkb/F1S1Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GNC6", "url": "https://www.uniprot.org/uniprotkb/K7GNC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GNC6-1", "url": "https://www.uniprot.org/uniprotkb/K7GNC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GP05", "url": "https://www.uniprot.org/uniprotkb/K7GP05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GP05-1", "url": "https://www.uniprot.org/uniprotkb/K7GP05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAFRMRKLTTMPVGLICASVSVHVAKEEESRKQLVKPEQLPIYTAPPLQSKYVEEQPGRLQVGFASIRTTTGRYLGWCKSAYVFMKNGIKDAVQFGKDAYVYLKNPPRDFLPKIGVITVSGLAGFVSARKGSRFKKIAYPLGLATIGATVCYPVQSVIIAKVTGKKAYTTSQEIYEAVKSLWTNNSKKESLPEPKEKTKLGNSAKIAIPAKTAQNLKQSVPLPTELSSETKTKSESTSGLFEITHS", "length": 247, "header": "tr|A0A5G2QZI2-1|A0A5G2QZI2_PIG Isoform 1 of MICOS complex subunit OS=Sus scrofa OX=9823 GN=APOOL PE=1 SV=1 CANONICAL=A0A5G2QZI2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2/entry#A0A5G2QZI2-1", "sequence": { "sequence": "MAAFRMRKLTTMPVGLICASVSVHVAKEEESRKQLVKPEQLPIYTAPPLQSKYVEEQPGRLQVGFASIRTTTGRYLGWCKSAYVFMKNGIKDAVQFGKDAYVYLKNPPRDFLPKIGVITVSGLAGFVSARKGSRFKKIAYPLGLATIGATVCYPVQSVIIAKVTGKKAYTTSQEIYEAVKSLWTNNSKKESLPEPKEKTKLGNSAKIAIPAKTAQNLKQSVPLPTELSSETKTKSESTSGLFEITHS", "length": 247, "header": "tr|A0A5G2QZI2-1|A0A5G2QZI2_PIG Isoform 1 of MICOS complex subunit OS=Sus scrofa OX=9823 GN=APOOL PE=1 SV=1 CANONICAL=A0A5G2QZI2-1" }, "locus": { "chromosome": "X", "start_pos": 68347755, "end_pos": 68281912, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082480.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082480.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070296.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070296.1" } ] } }, { "isoform_ac": "A0A5G2R976-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2/entry#A0A5G2R976-1", "sequence": { "sequence": "LKYFYNLPIYTAPPLQSKYVEEQPGRLQVGFASIRTTTGRYLGWCKSAYVFMKNGIKDAVQFGKDAYVYLKNPPRDFLPKIGVITVSGLAGFVSARKGSRFKKIAYPLGLATIGATVCYPVQSVIIAKVTGKKAYTTSQEIYEAVKSLWTNNSKKESLPEPKEKTKLGNSAKIAIPAKTAQNLKQSVPLPTELSSETKTKSESTSGATQFLLDPKLIDHGQSHPEDADMYSTRS", "length": 234, "header": "tr|A0A5G2R976-1|A0A5G2R976_PIG Computationally mapped isoform of MICOS complex subunit OS=Sus scrofa OX=9823 GN=APOOL PE=1 SV=2 CANONICAL=A0A5G2QZI2-1" }, "locus": { "chromosome": "X", "start_pos": 68354520, "end_pos": 68326673, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087140.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087140.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067155.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067155.2" } ] } }, { "isoform_ac": "F1S1Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2/entry#F1S1Q7-1", "sequence": { "sequence": "MAAFRLPIYTAPPLQSKYVEEQPGRLQVGFASIRTTTGRYLGWCKSAYVFMKNGIKDAVQFGKDAYVYLKNPPRDFLPKIGVITVSGLAGFVSARKGSRFKKIAYPLGLATIGATVCYPVQSVIIAKVTGKKAYTTSQEIYEAVKSLWTNNSKKESLPEPKEKTKLGNSAKIAIPAKTAQNLKQSVPLPTELSSETKTKSESTSGATQFLLDPKLIDHGQSHPEDADMYSTRS", "length": 233, "header": "tr|F1S1Q7-1|A0A5G2QZI2_PIG Computationally mapped isoform of MICOS complex subunit OS=Sus scrofa OX=9823 GN=APOOL PE=1 SV=3 CANONICAL=A0A5G2QZI2-1" }, "locus": { "chromosome": "X", "start_pos": 68354520, "end_pos": 68281912, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094429.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094429.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079511.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079511.1" } ] } }, { "isoform_ac": "K7GNC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2/entry#K7GNC6-1", "sequence": { "sequence": "MAFKPRLPIYTAPPLQSKYVEEQPGRLQVGFASIRTTTGRYLGWCKSAYVFMKNGIKDAVQFGKDAYVYLKNPPRDFLPKIGVITVSGLAGFVSARKGSRFKKIAYPLGLATIGATVCYPVQSVIIAKVTGKKAYTTSQEIYEAVKSLWTNNSKKESLPEPKEKTKLGNSAKIAIPAKTAQNLKQSVPLPTELSSETKTKSESTSGATQFLLDPKLIDHGQSHPEDADMYSTRS", "length": 234, "header": "tr|K7GNC6-1|A0A5G2QZI2_PIG Computationally mapped isoform of MICOS complex subunit OS=Sus scrofa OX=9823 GN=APOOL PE=1 SV=3 CANONICAL=A0A5G2QZI2-1" }, "locus": { "chromosome": "X", "start_pos": 68354520, "end_pos": 68327115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035731.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035731.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029378.3", "url": "https://www.ensembl.org/id/ENSSSCP00000029378.3" } ] } }, { "isoform_ac": "K7GP05-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2/entry#K7GP05-1", "sequence": { "sequence": "MRKLTTMPVGLICASVSVHVAKEEESRKQLVKPEQLPIYTAPPLQSKYVEEQPGRLQVGFASIRTTTGRYLGWCKSAYVFMKNGIKDAVQFGKDAYVYLKNPPRDFLPKIGVITVSGLAGFVSARKGSRFKKIAYPLGLATIGATVCYPVQSVIIAKLGNSAKIAIPAKTAQNLKQSVPLPTELSSETKTKSESTSGATQFLLDPKLIDHGQSHPEDADMYSTRS", "length": 225, "header": "tr|K7GP05-1|A0A5G2QZI2_PIG Computationally mapped isoform of MICOS complex subunit OS=Sus scrofa OX=9823 GN=APOOL PE=1 SV=2 CANONICAL=A0A5G2QZI2-1" }, "locus": { "chromosome": "X", "start_pos": 68354520, "end_pos": 68324036, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035584.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035584.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029614.2", "url": "https://www.ensembl.org/id/ENSSSCP00000029614.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "K7GNC6", "url": "https://www.uniprot.org/uniprotkb/K7GNC6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3SZ27-1", "protein_name": "MICOS complex subunit MIC27", "gene_name": "APOL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALRMGKLTTMPTGLIYASISVHVAKEEESKKQLVKPEQLPIYTAPPLQSKYVEEQPGHLQMGFASIRTTTSRYIGWCKGVYVFVKNGIMDTVQFGKDAYVYLKNPPRDFLPKIGVITVSGLAGFISARKGSRFKRIAYPLGLATLGATVCYPVQSVIIAKVAGKKAYATSQQMYEAVKSLWTKNNKKLPEHKEKTKLGSADETETPAETTHNLKHSVPLPAELSSETKTKSTSGATQFMPDPKLMDHGQSHPEDIDMYSTRS", "length": 264 }, "evidence": [ { "id": "A0A5G2QZI2", "url": "https://omabrowser.org/oma/group/A0A5G2QZI2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q78IK4-1", "protein_name": "MICOS complex subunit Mic27", "gene_name": "Apool", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAFRMGKLTTIPAGLIYASINVRLAKEEEPKKQLVRPDQLPIYTAPPLHSKYVEEQPGNLQRGFASIRTTTVYYIGWCKSIYLFMKNGVMDTVQFGKDAYVYLKNPPQDFLPKMGVITASGLAGLLSARKGSRFKKIAYPLGLATLGATVCYPAQSVIIAKITGKKAYATSQQIFQAIKSLWTQKSENESLPEPKEESKEGRSDEIHASLPDLKHSVSLPKELASATVIKSESTSGTTQFIPDPKLMDHGQSHPDDKDMYSTRS", "length": 265 }, "evidence": [ { "id": "A0A5G2QZI2", "url": "https://omabrowser.org/oma/group/A0A5G2QZI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cristae formation", "id": "GO:0042407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042407", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "MICOS complex", "id": "GO:0061617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061617", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZI2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 247, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZI2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZI2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZN2-1", "uniprot_ac": "A0A5G2QZN2", "uniprot_id": "A0A5G2QZN2_PIG", "mass": { "chemical_mass": 35314.0, "monoisotopic_mass": 35314.0 }, "refseq": {}, "gene_names": [ { "name": "LOC106508817", "type": "recommended", "evidence": [ { "id": "A0A5G2QZN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2" } ] } ], "protein_names": [ { "name": "MHC class I-like antigen recognition-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2QZN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC106508817", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2", "locus": {} } ], "crossref": [ { "id": "A0A5G2QZN2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041378", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041378", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050208", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050208", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16675:SF64", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16675:SF64", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QZN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLTHTTGLLLLTLLLLLKPRKTLRYAHSLCLNLAVTSQSRPRQPGVKSRAQWTQSLSSSMTVTATRSQLRAPWGEVNGTKAWSDLTGTLGGVGESSGWSCMSSLGTEKTTGAPRLQAKLCCQLEAERVTAASWHFSLDGQTALLLDAMDMNWTVVNPGATGIKEQWKLTVGDCGHWLREFLGHWENVLEQEPTEPPLEPSDNQQLPAWIIPRSGLTVIVVLVLVVIVLIIVIVIRRCDGRSGTTAGEKQAGLRLLGSACSGKGLGDLSPALTQALCTDPLYTRCWLLCLEPHSAQRGWGLLGSWGRRGCGGGTSHVSITWGAGTGRV", "length": 328, "header": "tr|A0A5G2QZN2-1|A0A5G2QZN2_PIG Isoform 1 of MHC class I-like antigen recognition-like domain-containing protein OS=Sus scrofa OX=9823 GN=LOC106508817 PE=4 SV=2 CANONICAL=A0A5G2QZN2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2/entry#A0A5G2QZN2-1", "sequence": { "sequence": "MSLTHTTGLLLLTLLLLLKPRKTLRYAHSLCLNLAVTSQSRPRQPGVKSRAQWTQSLSSSMTVTATRSQLRAPWGEVNGTKAWSDLTGTLGGVGESSGWSCMSSLGTEKTTGAPRLQAKLCCQLEAERVTAASWHFSLDGQTALLLDAMDMNWTVVNPGATGIKEQWKLTVGDCGHWLREFLGHWENVLEQEPTEPPLEPSDNQQLPAWIIPRSGLTVIVVLVLVVIVLIIVIVIRRCDGRSGTTAGEKQAGLRLLGSACSGKGLGDLSPALTQALCTDPLYTRCWLLCLEPHSAQRGWGLLGSWGRRGCGGGTSHVSITWGAGTGRV", "length": 328, "header": "tr|A0A5G2QZN2-1|A0A5G2QZN2_PIG Isoform 1 of MHC class I-like antigen recognition-like domain-containing protein OS=Sus scrofa OX=9823 GN=LOC106508817 PE=4 SV=2 CANONICAL=A0A5G2QZN2-1" }, "locus": { "chromosome": "1", "start_pos": 16098797, "end_pos": 16096074, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077619.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077619.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067408.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067408.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "antigen processing and presentation of endogenous peptide antigen via MHC class Ib", "id": "GO:0002476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002476", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2" } ], "pmid": "" }, { "name": "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent", "id": "GO:0002486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002486", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2" } ], "pmid": "" }, { "name": "positive regulation of T cell mediated cytotoxicity", "id": "GO:0001916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001916", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2" } ], "pmid": "" }, { "name": "natural killer cell mediated cytotoxicity", "id": "GO:0042267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042267", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "natural killer cell lectin-like receptor binding", "id": "GO:0046703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046703", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2" } ], "pmid": "" }, { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZN2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 328, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZN2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZN2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZP4-1", "uniprot_ac": "A0A5G2QZP4", "uniprot_id": "A0A5G2QZP4_PIG", "mass": { "chemical_mass": 34912.0, "monoisotopic_mass": 34912.0 }, "refseq": {}, "gene_names": [ { "name": "IL20RB", "type": "recommended", "evidence": [ { "id": "A0A5G2QZP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4" } ] }, { "name": "NCK1", "type": "recommended", "evidence": [ { "id": "A0A5G2QZP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4" } ] }, { "name": "IL20RB", "type": "synonym", "evidence": [ { "id": "A0A5G2QZP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4" } ] } ], "protein_names": [ { "name": "Interleukin 20 receptor subunit beta", "type": "synonym", "evidence": [ { "id": "A0A5G2QZP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NCK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4", "locus": { "chromosome": "13", "start_pos": 77945468, "end_pos": 77863701, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000025701", "url": "https://www.ensembl.org/id/ENSSSCG00000025701" } ] } } ], "crossref": [ { "id": "A0A5G2QZP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000025701", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000025701", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100620875", "url": "https://www.ncbi.nlm.nih.gov/gene/100620875", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100620875", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620875", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QGEYERY", "url": "https://omabrowser.org/oma/group/QGEYERY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "I3LSK3", "url": "https://www.orthodb.org/?gene=I3LSK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20859", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20859", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20859:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20859:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01108", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01108", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5684996", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5684996", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8854691", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854691", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QZP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LSK3", "url": "https://www.uniprot.org/uniprotkb/I3LSK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LSK3-1", "url": "https://www.uniprot.org/uniprotkb/I3LSK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLEEIAASLMWFSYALIPCLLTDGVAVLPAPQNISVQSTNMKHVLTWSPVMVPEEIVYYSVEYQGEYESLYMSHIWIPSNWCSPTTGLECDITDDITATVPYNLRVRATLGSQTSAWSTLKHPFNRNSTTLIPPGMEVTKDGFHLVIKLEDLGPQFEFFVAYWRREPGAKEHVKVVRPGGIPMHLETMEPGATYCVKARTFVKAIGRYSAFSQAECVKVQGESLPLALALFAFVGFMLVLVVVPFSVWKMGRLLRRSCCPVVVLPDTLPARLSLFMAPRETCSQTQKCKKWEIHPETFPSSKCQLLVALQ", "length": 311, "header": "tr|A0A5G2QZP4-1|A0A5G2QZP4_PIG Isoform 1 of Interleukin 20 receptor subunit beta OS=Sus scrofa OX=9823 GN=NCK1 PE=4 SV=1 CANONICAL=A0A5G2QZP4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4/entry#A0A5G2QZP4-1", "sequence": { "sequence": "MVLEEIAASLMWFSYALIPCLLTDGVAVLPAPQNISVQSTNMKHVLTWSPVMVPEEIVYYSVEYQGEYESLYMSHIWIPSNWCSPTTGLECDITDDITATVPYNLRVRATLGSQTSAWSTLKHPFNRNSTTLIPPGMEVTKDGFHLVIKLEDLGPQFEFFVAYWRREPGAKEHVKVVRPGGIPMHLETMEPGATYCVKARTFVKAIGRYSAFSQAECVKVQGESLPLALALFAFVGFMLVLVVVPFSVWKMGRLLRRSCCPVVVLPDTLPARLSLFMAPRETCSQTQKCKKWEIHPETFPSSKCQLLVALQ", "length": 311, "header": "tr|A0A5G2QZP4-1|A0A5G2QZP4_PIG Isoform 1 of Interleukin 20 receptor subunit beta OS=Sus scrofa OX=9823 GN=NCK1 PE=4 SV=1 CANONICAL=A0A5G2QZP4-1" }, "locus": { "chromosome": "13", "start_pos": 77981908, "end_pos": 77952527, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080242.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080242.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063715.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063715.1" } ] } }, { "isoform_ac": "I3LSK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4/entry#I3LSK3-1", "sequence": { "sequence": "MVLEEIAASLMWFSYALIPCLLTDGVAVLPAPQNISVQSTNMKHVLTWSPVMVPEEIVYYSVEYQGEYESLYMSHIWIPSNWCSPTTGLECDITDDITATVPYNLRVRATLGSQTSAWSTLKHPFNRNSTTLIPPGMEVTKDGFHLVIKLEDLGPQFEFFVAYWRREPGAKEHVKVVRPGGIPMHLETMEPGATYCVKARTFVKAIGRYSAFSQAECVKVQGESLPLALALFAFVGFMLVLVVVPFSVWKMGRLLRRSCCPVVVLPDTLKITSSPQKLISCRREEVEACATAGLSSEELLRAWI", "length": 304, "header": "tr|I3LSK3-1|A0A5G2QZP4_PIG Computationally mapped isoform of Interleukin 20 receptor subunit beta OS=Sus scrofa OX=9823 GN=NCK1 PE=4 SV=2 CANONICAL=A0A5G2QZP4-1" }, "locus": { "chromosome": "13", "start_pos": 77985318, "end_pos": 77952527, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025385.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025385.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027096.2", "url": "https://www.ensembl.org/id/ENSSSCP00000027096.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LSK3", "url": "https://www.uniprot.org/uniprotkb/I3LSK3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100620875", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620875", "resource": "KEGG Pathway" }, { "id": "R-SSC-5684996", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5684996", "resource": "Reactome", "description": "MAPK1/MAPK3 signaling" }, { "id": "R-SSC-8854691", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854691", "resource": "Reactome", "description": "Interleukin-20 family signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q9A6-1", "protein_name": "Interleukin 20 receptor beta", "gene_name": "Il20rb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MISQGVWTSPFMWFFYSMTSGFLTDAVSVLPAPQNLSVQSTNMKHLLMWNPVTQPGETVLYCVEYQGEYESLYMSHIWIPSSQCSPTKSLECDVTDDITATVPYNFRVKAMLGSQTSAWSNLEHPFNRNATVLTPPRMEVTEHGLHLVIELEDLGPQFEFLVVYWRREPGAAEHVKMVRSGDIPVHLETMEPGAMYCVKAQALVKAIGRHSAFSQPTCVEMQGESLPLALALFAFVGFMLILVVVLLSVWKMGQLLRYSCCPAVVLPDTLKITSSSQKLISCRKEEVDACAVAVLSSEHLFGVWISQT", "length": 308 }, "evidence": [ { "id": "A0A5G2QZP4", "url": "https://omabrowser.org/oma/group/A0A5G2QZP4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UXL0-1", "protein_name": "Interleukin-20 receptor subunit beta", "gene_name": "IL20RB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQTFTMVLEEIWTSLFMWFFYALIPCLLTDEVAILPAPQNLSVLSTNMKHLLMWSPVIAPGETVYYSVEYQGEYESLYTSHIWIPSSWCSLTEGPECDVTDDITATVPYNLRVRATLGSQTSAWSILKHPFNRNSTILTRPGMEITKDGFHLVIELEDLGPQFEFLVAYWRREPGAEEHVKMVRSGGIPVHLETMEPGAAYCVKAQTFVKAIGRYSAFSQTECVEVQGEAIPLVLALFAFVGFMLILVVVPLFVWKMGRLLQYSCCPVVVLPDTLKITNSPQKLISCRREEVDACATAVMSPEELLRAWIS", "length": 311 }, "evidence": [ { "id": "A0A5G2QZP4", "url": "https://omabrowser.org/oma/group/A0A5G2QZP4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4" } ], "pmid": "" }, { "name": "interleukin-20 binding", "id": "GO:0042015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042015", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZP4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZP4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZP4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP4" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 130, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZP6-1", "uniprot_ac": "A0A5G2QZP6", "uniprot_id": "A0A5G2QZP6_PIG", "mass": { "chemical_mass": 286135.0, "monoisotopic_mass": 286135.0 }, "refseq": {}, "gene_names": [ { "name": "ZAN", "type": "recommended", "evidence": [ { "id": "A0A5G2QZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6" } ] } ], "protein_names": [ { "name": "Zonadhesin", "type": "recommended", "evidence": [ { "id": "A0A5G2QZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZP6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6#function" }, { "database": "UniProtKB", "id": "ARBA00057483", "url": "https://www.uniprot.org/uniprotkb/ARBA00057483#function" }, { "database": "UniProtKB", "id": "A0A5G2RK05", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK05#function" }, { "database": "UniProtKB", "id": "A0A8W4FML9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FML9#function" }, { "database": "UniProtKB", "id": "F1RMX7", "url": "https://www.uniprot.org/uniprotkb/F1RMX7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZP6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZAN", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6", "locus": { "chromosome": "3", "start_pos": 8668880, "end_pos": 8632701, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007674", "url": "https://www.ensembl.org/id/ENSSSCG00000007674" } ] } } ], "crossref": [ { "id": "ENSSSCG00000007674", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007674", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QLCICEG", "url": "https://omabrowser.org/oma/group/QLCICEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46160:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46160:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00629", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00629", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QZP6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RK05", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RK05-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FML9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FML9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FML9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FML9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RMX7", "url": "https://www.uniprot.org/uniprotkb/F1RMX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RMX7-1", "url": "https://www.uniprot.org/uniprotkb/F1RMX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPLWILVLQLGAAPARKEKPLDWKTVARNSRDNSLLTQCDFEDDSRPLCDWTQASSDDGDWTRTSRPSSTGSTGPPGGYPNGEGYYLHMESNKFHQGKVARLHSPLIWEQGPLCVRFAYYMFGLSWGAQLKLLLTSGSKGKHPNVLWKHSNAQSPSWMPTAVTVPTGLILPGRLTFEGVRGSTAYLDIALDTISIRRGSCNRICMMQTCSFDTPNDLCGWSWIPTATGAKWVQKKGSTGVPNVGPEDDFSSPGSGFYMLLDPKNAKPRQRSALLSPLIQSSGCLSLSFQYTQRGQASGATLMVYASVLGSIRKHTLFSGQPGPSWQPVSVNYTSQGQIQFTLVGVFGKIPEPAVAVDAISIAPCEESFPQCDFEDNAHPFCDWVQASQDGGYWRQGNKNTFIQPAGPFGISLNGEGHYIFLETDKFSQAGQSFRLVSRPFCAPAVICVTFTYHMYGLGQGTKLRLLLGSPAGSPPSSLWERVGPQSPEWLNTSVTIPSGHQQPMQLIFEAVRGTNTAFVVALGFVLINHGTCRIGPSETSVSTEKPVAPTEKPTVPSEIYTIPTEKPMVHMEKPIVHTEKPTVPTEKPTIPTEKSTVPTKKPTVFKEPTLPPEGPTVPAEQPTTPPEGPAVPPKGPTVLTEWPTSHTEKSTVHTEKPILPTGKSTIPTEKPMVPTKRTTTPTERTTIPAEKPTVPIEKPMVPTERTTIPTERTTIPTEKPTVPTEKLTVPTEKPIVPTEKPIVPTEKHTIPTEKLTVLTERTTTPTERTTIPTEKPTVPTEKPSVPTEKPTVPTEEPTIPTEKLTVPTERTTTPTKRTTTPTIRTTTPTIRTTTPTERTTTPTIRTTTPTERTTIPTKKTTVPTEKTIIPTERTIAPTTPQPSPTLVPTQPAAVVMPSTSATTVTPRTTILGTDWFSPNCTEHCHCRPSSRMECQTFKCGTHTVCQLKNGQYGCHPYAGSATCSVYGDPHYLTFDGRRFNFMGKCTYILAQPCGNLTEHFFRVLVKKEERGQEGVSCLSKVYVTLPESTVTLLKGRHTLVGGQRVTLPAIPSRGVFLAPSGRFVELQTAFGLRVRWDGDQQLFVSVPSTFSGKLCGLCGDYDGDSSNDNQKPDGSPAKDEKELGSSWQTSEDADQQCEENQVSPPSCNTALQNTMSGPEFCGQLVAPHGVFEACLPHLRASSFFKSCTFDMCNFQGLQHMLCAHMSALTENCQDAGYTVKPWRGPQFCPLACPRNSRYTLCARLCPDTCHSEFSGRACKDRCVEGCECDPGFVLSGLQCVSRSECGCLDSTAGYVKVGERWFKPGCRQLCICEGNNRTRCVLWRCQAQEFCGQQDGIYGCHAQGSATCTVSGDPHYLTFDGALHHFTGTCTYTLTKPCWLRSLENSFLVSATNEFRGGNLEASYVRAVQVQVFNLRISLIKGRKVTLDGRRVALPLWPAQGRVSIMSSGSFILLYTDFGLQVRYDGDHLVEVTVPSSYAGRLCGLCGNYNNNSLDDILQPDKRPASSSVRLGASWKINELSEPGCFAEGGKPPRCLGKEVADAWRKNCDVLMNPQGPFSQCHRVVAPQSSFSSCLYGQCATKGDTLTLCRSLQAYASLCARAGQALTWRNGTFCPLKCPSGSSYSTCANPCPATCLSLNNPSYCPSTLPCAEGCECQKGHILSGTSCVPLSQCGCTTQRGSYHPVGESWYTDNSCSRLCTCSAHNNISCRQASCKPSQMCWPQDGLIRCRVAGMGVCRIPDTSHYVSFDGSYHAVRGNCTYVLVKICHSTMDLPFFKISGENGKREGQPPAFYLRQVYVDIFNTLVTLKQDQVLINGTRVSLPATTQIRGVRVISRDGYTVLTINIGVQVKFDGRGFLEVEIPKAYYGRTCGVCGNFNDEEEDELMMPSDALALDDVMYVDSWRDKEIDPNCQEDDRKTEAESQEQPSANCRPADLERAQEQCQAAFQAPAWANCATRVVLSPYVRSCTHKLCEFGGLNRAFCESLQAFGAACQAQGIKPPVWRNSSFCPLDCSAHSVYTSCVPSCLPSCQDPEGQCTGAGAPSTCEEGCICEPGYVLSEQQCVARSQCGCRDARGTFLPVGRFRLSSGCSQMCVCTAGAIECRPFTCPSGSQCEPNEDGKDFCQPNSSNLCSVFGDPHYRTFDGLSYRFQGRMTYTLVKTLDVLPDGVEPLVVEGRNKVYPSLTPVFLQEIIVMVYGYTVQLQAELELVVNGQKVSIPYKPNEYLQVTLRGRRLYLVTDFELVVSFNGRNNAVIAMPSTYLGLVRGLCGNYDKNKRNDFMLPNGSFTQNLLVFGNSWEVKAKEGHPRFSRAIREEEEKNEESGFQNVSECSPEQLELVNHTQACGVLVDPQGPFAACHQIVAPGPFQEHCVFDLCAAPGPKEQEELRCQVLSGLAMSGQHGLSELYDTLPSLLCHPGSPPGLRRPVCGGLCQPPRLHLQWCPEPSLAHCGCTNNGVYYQQGDSFVTENCSQRCTCASSGVLLCEPLSCRPGEICTLGNLTRGCFRDSPCLQNPCQNDGRCREQGTHFTCECELGYGGDLCTEPRGVPSPKKPASNRVAILLGMLMPTVLLVPAVTRVSRKRRRRRRERTQSQNRGKRAGTDCAPEQAYKVA", "length": 2614, "header": "tr|A0A5G2QZP6-1|A0A5G2QZP6_PIG Isoform 1 of Zonadhesin OS=Sus scrofa OX=9823 GN=ZAN PE=4 SV=2 CANONICAL=A0A5G2QZP6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6/entry#A0A5G2QZP6-1", "sequence": { "sequence": "MAPPLWILVLQLGAAPARKEKPLDWKTVARNSRDNSLLTQCDFEDDSRPLCDWTQASSDDGDWTRTSRPSSTGSTGPPGGYPNGEGYYLHMESNKFHQGKVARLHSPLIWEQGPLCVRFAYYMFGLSWGAQLKLLLTSGSKGKHPNVLWKHSNAQSPSWMPTAVTVPTGLILPGRLTFEGVRGSTAYLDIALDTISIRRGSCNRICMMQTCSFDTPNDLCGWSWIPTATGAKWVQKKGSTGVPNVGPEDDFSSPGSGFYMLLDPKNAKPRQRSALLSPLIQSSGCLSLSFQYTQRGQASGATLMVYASVLGSIRKHTLFSGQPGPSWQPVSVNYTSQGQIQFTLVGVFGKIPEPAVAVDAISIAPCEESFPQCDFEDNAHPFCDWVQASQDGGYWRQGNKNTFIQPAGPFGISLNGEGHYIFLETDKFSQAGQSFRLVSRPFCAPAVICVTFTYHMYGLGQGTKLRLLLGSPAGSPPSSLWERVGPQSPEWLNTSVTIPSGHQQPMQLIFEAVRGTNTAFVVALGFVLINHGTCRIGPSETSVSTEKPVAPTEKPTVPSEIYTIPTEKPMVHMEKPIVHTEKPTVPTEKPTIPTEKSTVPTKKPTVFKEPTLPPEGPTVPAEQPTTPPEGPAVPPKGPTVLTEWPTSHTEKSTVHTEKPILPTGKSTIPTEKPMVPTKRTTTPTERTTIPAEKPTVPIEKPMVPTERTTIPTERTTIPTEKPTVPTEKLTVPTEKPIVPTEKPIVPTEKHTIPTEKLTVLTERTTTPTERTTIPTEKPTVPTEKPSVPTEKPTVPTEEPTIPTEKLTVPTERTTTPTKRTTTPTIRTTTPTIRTTTPTERTTTPTIRTTTPTERTTIPTKKTTVPTEKTIIPTERTIAPTTPQPSPTLVPTQPAAVVMPSTSATTVTPRTTILGTDWFSPNCTEHCHCRPSSRMECQTFKCGTHTVCQLKNGQYGCHPYAGSATCSVYGDPHYLTFDGRRFNFMGKCTYILAQPCGNLTEHFFRVLVKKEERGQEGVSCLSKVYVTLPESTVTLLKGRHTLVGGQRVTLPAIPSRGVFLAPSGRFVELQTAFGLRVRWDGDQQLFVSVPSTFSGKLCGLCGDYDGDSSNDNQKPDGSPAKDEKELGSSWQTSEDADQQCEENQVSPPSCNTALQNTMSGPEFCGQLVAPHGVFEACLPHLRASSFFKSCTFDMCNFQGLQHMLCAHMSALTENCQDAGYTVKPWRGPQFCPLACPRNSRYTLCARLCPDTCHSEFSGRACKDRCVEGCECDPGFVLSGLQCVSRSECGCLDSTAGYVKVGERWFKPGCRQLCICEGNNRTRCVLWRCQAQEFCGQQDGIYGCHAQGSATCTVSGDPHYLTFDGALHHFTGTCTYTLTKPCWLRSLENSFLVSATNEFRGGNLEASYVRAVQVQVFNLRISLIKGRKVTLDGRRVALPLWPAQGRVSIMSSGSFILLYTDFGLQVRYDGDHLVEVTVPSSYAGRLCGLCGNYNNNSLDDILQPDKRPASSSVRLGASWKINELSEPGCFAEGGKPPRCLGKEVADAWRKNCDVLMNPQGPFSQCHRVVAPQSSFSSCLYGQCATKGDTLTLCRSLQAYASLCARAGQALTWRNGTFCPLKCPSGSSYSTCANPCPATCLSLNNPSYCPSTLPCAEGCECQKGHILSGTSCVPLSQCGCTTQRGSYHPVGESWYTDNSCSRLCTCSAHNNISCRQASCKPSQMCWPQDGLIRCRVAGMGVCRIPDTSHYVSFDGSYHAVRGNCTYVLVKICHSTMDLPFFKISGENGKREGQPPAFYLRQVYVDIFNTLVTLKQDQVLINGTRVSLPATTQIRGVRVISRDGYTVLTINIGVQVKFDGRGFLEVEIPKAYYGRTCGVCGNFNDEEEDELMMPSDALALDDVMYVDSWRDKEIDPNCQEDDRKTEAESQEQPSANCRPADLERAQEQCQAAFQAPAWANCATRVVLSPYVRSCTHKLCEFGGLNRAFCESLQAFGAACQAQGIKPPVWRNSSFCPLDCSAHSVYTSCVPSCLPSCQDPEGQCTGAGAPSTCEEGCICEPGYVLSEQQCVARSQCGCRDARGTFLPVGRFRLSSGCSQMCVCTAGAIECRPFTCPSGSQCEPNEDGKDFCQPNSSNLCSVFGDPHYRTFDGLSYRFQGRMTYTLVKTLDVLPDGVEPLVVEGRNKVYPSLTPVFLQEIIVMVYGYTVQLQAELELVVNGQKVSIPYKPNEYLQVTLRGRRLYLVTDFELVVSFNGRNNAVIAMPSTYLGLVRGLCGNYDKNKRNDFMLPNGSFTQNLLVFGNSWEVKAKEGHPRFSRAIREEEEKNEESGFQNVSECSPEQLELVNHTQACGVLVDPQGPFAACHQIVAPGPFQEHCVFDLCAAPGPKEQEELRCQVLSGLAMSGQHGLSELYDTLPSLLCHPGSPPGLRRPVCGGLCQPPRLHLQWCPEPSLAHCGCTNNGVYYQQGDSFVTENCSQRCTCASSGVLLCEPLSCRPGEICTLGNLTRGCFRDSPCLQNPCQNDGRCREQGTHFTCECELGYGGDLCTEPRGVPSPKKPASNRVAILLGMLMPTVLLVPAVTRVSRKRRRRRRERTQSQNRGKRAGTDCAPEQAYKVA", "length": 2614, "header": "tr|A0A5G2QZP6-1|A0A5G2QZP6_PIG Isoform 1 of Zonadhesin OS=Sus scrofa OX=9823 GN=ZAN PE=4 SV=2 CANONICAL=A0A5G2QZP6-1" }, "locus": { "chromosome": "3", "start_pos": 8668831, "end_pos": 8632701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086847.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086847.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067423.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067423.2" } ] } }, { "isoform_ac": "A0A5G2RK05-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6/entry#A0A5G2RK05-1", "sequence": { "sequence": "MAPPLWILVLQLGAAPARKEKPLDWKTVARNSRDNSLLTQCDFEDDSRPLCDWTQASSDDGDWTRTSRPSSTGSTGPPGGYPNGEGYYLHMESNKFHQGKVARLHSPLIWEQGPLCVRFAYYMFGLSWGAQLKLLLTSGSKGKHPNVLWKHSNAQSPSWMPTAVTVPTGLILPGRLTFEGVRGSTAYLDIALDTISIRRGSCNRICMMQTCSFDTPNDLCGWSWIPTATGAKWVQKKGSTGVPNVGPEDDFSSPGSGFYMLLDPKNAKPRQRSALLSPLIQSSGCLSLSFQYTQRGQASGATLMVYASVLGSIRKHTLFSGQPGPSWQPVSVNYTSQGQIQFTLVGVFGKIPEPAVAVDAISIAPCEESFPQCDFEDNAHPFCDWVQASQDGGYWRQGNKNTFIQPAGPFGISLNGEGHYIFLETDKFSQAGQSFRLVSRPFCAPAVICVTFTYHMYGLGQGTKLRLLLGSPAGSPPSSLWERVGPQSPEWLNTSVTIPSGHQQPMQLIFEAVRGTNTAFVVALGFVLINHGTCRIGPSETSVSTEKPVAPTEKPTVPSEIYTIPTEKPMVHMEKPIVHTEKPTVPTEKPTIPTEKSTVPTKKPTVFKEPTLPPEGPTVPAEQPTTPPEGPAVPPKGPTVLTEWPTSHTEKSTVHTEKPILPTGKSTIPTEKPMVPTKRTTTPTERTTIPAEKPTVPIEKPMVPTERTTIPTERTTIPTEKPTVPTEKLTVPTEKPIVPTEKPIVPTEKHTIPTEKLTVLTERTTTPTERTTIPTEKPTVPTEKPSVPTEKPTVPTEEPTIPTEKLTVPTERTTTPTKRTTTPTIRTTTPTIRTTTPTERTTTPTIRTTTPTERTTIPTKKTTVPTEKTIIPTERTIAPTTPQPSPTLVPTQPAAVVMPSTSATTVTPRTTILGTDWFSPNCTEHCHCRPSSRMECQTFKCGTHTVCQLKNGQYGCHPYAGSATCSVYGDPHYLTFDGRRFNFMGKCTYILAQPCGNLTEHFFRVLVKKEERGQEGVSCLSKVYVTLPESTVTLLKGRHTLVGGQRVTLPAIPSRGVFLAPSGRFVELQTAFGLRVRWDGDQQLFVSVPSTFSGKLCGLCGDYDGDSSNDNQKPDGSPAKDEKELGSSWQTSEDADQQCEENQVSPPSCNTALQNTMSGPEFCGQLVAPHGVFEACLPHLRASSFFKSCTFDMCNFQGLQHMLCAHMSALTENCQDAGYTVKPWRGPQFCPLACPRNSRYTLCARLCPDTCHSEFSGRACKDRCVEGCECDPGFVLSGLQCVSRSECGCLDSTAGYVKVGERWFKPGCRQLCICEGNNRTRCVLWRCQAQEFCGQQDGIYGCHAQGSATCTVSGDPHYLTFDGALHHFTGTCTYTLTKPCWLRSLENSFLVSATNEFRGGNLEASYVRAVQVQVFNLRISLIKGRKVTLDGRRVALPLWPAQGRVSIMSSGSFILLYTDFGLQVRYDGDHLVEVTVPSSYAGRLCGLCGNYNNNSLDDILQPDKRPASSSVRLGASWKINELSEPGCFAEGGKPPRCLGKEVADAWRKNCDVLMNPQGPFSQCHRVVAPQSSFSSCLYGQCATKGDTLTLCRSLQAYASLCARAGQALTWRNGTFCPLKCPSGSSYSTCANPCPATCLSLNNPSYCPSTLPCAEGCECQKGHILSGTSCVPLSQCGCTTQRGSYHPVGESWYTDNSCSRLCTCSAHNNISCRQASCKPSQMCWPQDGLIRCRVAGMGVCRIPDTSHYVSFDGSYHAVRGNCTYVLVKICHSTMDLPFFKISGENGKREGQPPAFYLRQVYVDIFNTLVTLKQDQVLINGTRVSLPATTQIRGVRVISRDGYTVLTINIGVQVKFDGRGFLEVEIPKAYYGRTCGVCGNFNDEEEDELMMPSDALALDDVMYVDSWRDKEIDPNCQEDDRKTEAESQEQPSANCRPADLERAQEQCQAAFQAPAWANCATRVVLSPYVRSCTHKLCEFGGLNRAFCESLQAFGAACQAQGIKPPVWRNSSFCPLDCSAHSVYTSCVPSCLPSCQDPEGQCTGAGAPSTCEEGCICEPGYVLSEQQCVARSQCGCRDARGTFLPVGRFRLSSGCSQMCVCTAGAIECRPFTCPSGSQCEPNEDGKDFCQPNSSNLCSVFGDPHYRTFDGLSYRFQGRMTYTLVKTLDVLPDGVEPLVVEGRNKVYPSLTPVFLQEIIVMVYGYTVQLQAELELVVNGQKVSIPYKPNEYLQVTLRGRRLYLVTDFELVVSFNGRNNAVIAMPSTYLGLVRGLCGNYDKNKRNDFMLPNGSFTQNLLVFGNSWEVKAKEGHPRFSRAIREEEEKNEESGFQNVSECSPEQLELVNHTQACGVLVDPQGPFAACHQIVAPGPFQEHCVFDLCAAPGPKEQEELRCQVLSGYAIICQESGATLAGWRDHTHCDSPCLQNPCQNDGRCREQGTHFTCECELGYGGDLCTEPRGVPSPKKPASNRVAILLGMLMPTVLLVPAVTRVSRKRRRRRRERTQSQNRGKRAGTDCAPEQAYKVA", "length": 2523, "header": "tr|A0A5G2RK05-1|A0A5G2RK05_PIG Computationally mapped isoform of Zonadhesin OS=Sus scrofa OX=9823 GN=ZAN PE=4 SV=2 CANONICAL=A0A5G2QZP6-1" }, "locus": { "chromosome": "3", "start_pos": 8668831, "end_pos": 8632701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078565.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078565.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072325.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072325.2" } ] } }, { "isoform_ac": "A0A8W4FML9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6/entry#A0A8W4FML9-1", "sequence": { "sequence": "MLGLPALAGPMAMPHPPLIPSTPTLLAFSFPGGFYMLLDPKNAKPRQRSALLSPLIQSSGCLSLSFQYTQRGQASGATLMVYASVLGSIRKHTLFSGQPGPSWQPVSVNYTSQGQIQFTLVGVFGKIPEPAVAVDAISIAPCEESFPQCDFEDNAHPFCDWVQASQDGGYWRQGNKNTFIQPAGPFGISLNGEGHYIFLETDKFSQAGQSFRLVSRPFCAPAVICVTFTYHMYGLGQGTKLRLLLGSPAGSPPSSLWERVGPQSPEWLNTSVTIPSGHQQPMQLIFEAVRGTNTAFVVALGFVLINHGTCRGPSETSVSTEKPVAPTEKPTVPSEIYTIPTEKPMVHMEKPIVHTEKPTVPTEKPTIPTEKSTVPTKKPTVFKEPTLPPEGPTVPAEQPTTPPEGPAVPPKGPTVLTEWPTSHTEKSTVHTEKPILPTGKSTIPTEKPMVPTKRTTTPTERTTIPAEKPTVPIEKPMVPTERTTIPTERTTIPTEKPTVPTEKLTVPTEKPIVPTEKPIVPTEKHTIPTEKLTVLTERTTTPTERTTIPTEKPTVPTEKPSVPTEKPTVPTEEPTIPTEKLTVPTERTTTPTKRTTTPTIRTTTPTIRTTTPTERTTTPTIRTTTPTERTTIPTKKTTVPTEKTIIPTERTIAPTTPQPSPTLVPTQPAAVVMPSTSATTVTPRTTIASCPPNAHFERCACPVSCQSPTPNCELFCKPGCVCDPGFLFSGSHCVNASSCDCFYNDNYYKLGTDWFSPNCTEHCHCRPSSRMECQTFKCGTHTVCQLKNGQYGCHPYGSATCSVYGDPHYLTFDGRRFNFMGKCTYILAQPCGNLTEHFFRVLVKKEERGQEGVSCLSKVYVTLPESTVTLLKGRHTLVGGQRVTLPAIPSRGVFLAPSGRFVELQTAFGLRVRWDGDQQLFVSVPSTFSGKLCGLCGDYDGDSSNDNQKPDGSPAKDEKELGSSWQTSEDADQQCEENQVSPPSCNTALQNTMSGPEFCGQLVAPHGVFEACLPHLRASSFFKSCTFDMCNFQGLQHMLCAHMSALTENCQDAGYTVKPWRGPQFCPLACPRNSRYTLCARLCPDTCHSEFSGRACKDRCVEGCECDPGFVLSGLQCVSRSECGCLDSTAGYVKVGERWFKPGCRQLCICEGNNRTRCVLWRCQAQEFCGQQDGIYGCHAQGSATCTVSGDPHYLTFDGALHHFTGTCTYTLTKPCWLRSLENSFLVSATNEFRGGNLEASYVRAVQVQVFNLRISLIKGRKVTLDGRRVALPLWPAQGRVSIMSSGSFILLYTDFGLQVRYDGDHLVEVTVPSSYAGRLCGLCGNYNNNSLDDILQPDKRPASSSVRLGASWKINELSEPGCFAEGGKPPRCLGKEVADAWRKNCDVLMNPQGPFSQCHRVVAPQSSFSSCLYGQCATKGDTLTLCRSLQAYASLCARAGQALTWRNGTFCPLKCPSGSSYSTCANPCPATCLSLNNPSYCPSTLPCAEGCECQKGHILSGTSCVPLSQCGCTTQRGSYHPVGESWYTDNSCSRLCTCSAHNNISCRQASCKPSQMCWPQDGLIRCRVAGMGVCRIPDTSHYVSFDGSYHAVRGNCTYVLVKICHSTMDLPFFKISGENGKREGQPPAFYLRQVYVDIFNTLVTLKQDQVLINGTRVSLPATTQIRGVRVISRDGYTVLTINIGVQVKFDGRGFLEVEIPKAYYGRTCGVCGNFNDEEEDELMMPSDALALDDVMYVDSWRDKEIDPNCQEDDRKTEAESQEQPSANCRPADLERAQEQCQAAFQAPAWANCATRVVLSPYVRSCTHKLCEFGGLNRAFCESLQAFGAACQAQGIKPPVWRNSSFCPLDCSAHSVYTSCVPSCLPSCQDPEGQCTGAGAPSTCEEGCICEPGYVLSEQQCVARSQCGCRDARGTFLPVGRFRLSSGCSQMCVCTAGAIECRPFTCPSGSQCEPNEDGKDFCQPNSSNLCSVFGDPHYRTFDGLSYRFQGRMTYTLVKTLDVLPDGVEPLVVEGRNKVYPSLTPVFLQEIIVMVYGYTVQLQAELELVVNGQKVSIPYKPNEYLQVTLRGRRLYLVTDFELVVSFNGRNNAVIAMPSTYLGLVRGLCGNYDKNKRNDFMLPNGSFTQNLLVFGNSWEVKAKEGHPRFSRAIREEEEKNEESGFQNVSECSPEQLELVNHTQACGVLVDPQGPFAACHQIVAPGPFQEHCVFDLCAAPGPKEQEELRCQVLSGYAIICQESGATLAGWRDHTHCALPCPANTVYQSCMTPCPASCATLAVPRACDGPCVEGCASLPGYIYSGAQSLPMAHCGCTNNGVYYQQGDSFVTENCSQRCTCASSGVLLCEPLSCRPGEICTLGNLTRGCFRDSPCLQNPCQNDGRCREQGTHFTCECELGYGGDLCTEPRGVPSPKKPEASNRVAILLGMLMPTVLLVPAVTRVSRKRRRRRRPSRERTQSQNRGKRAGTDCAPEQAYKVA", "length": 2476, "header": "tr|A0A8W4FML9-1|A0A5G2QZP6_PIG Computationally mapped isoform of Zonadhesin OS=Sus scrofa OX=9823 GN=ZAN PE=4 SV=1 CANONICAL=A0A5G2QZP6-1" }, "locus": { "chromosome": "3", "start_pos": 8668831, "end_pos": 8638719, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092631.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092631.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080598.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080598.1" } ] } }, { "isoform_ac": "F1RMX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6/entry#F1RMX7-1", "sequence": { "sequence": "MLGLPALAGPMAMPHPPLIPSTPTLLAFSFPGGFYMLLDPKNAKPRQRSALLSPLIQSSGCLSLSFQYTQRGQASGATLMVYASVLGSIRKHTLFSGQPGPSWQPVSVNYTSQGQIQFTLVGVFGKIPEPAVAVDAISIAPCEESFPQCDFEDNAHPFCDWVQASQDGGYWRQGNKNTFIQPAGPFGISLNGEGHYIFLETDKFSQAGQSFRLVSRPFCAPAVICVTFTYHMYGLGQGTKLRLLLGSPAGSPPSSLWERVGPQSPEWLNTSVTIPSGHQQPMQLIFEAVRGTNTAFVVALGFVLINHGTCRGPSETSVSTEKPVAPTEKPTVPSEIYTIPTEKPMVHMEKPIVHTEKPTVPTEKPTIPTEKSTVPTKKPTVFKEPTLPPEGPTVPAEQPTTPPEGPAVPPKGPTVLTEWPTSHTEKSTVHTEKPILPTGKSTIPTEKPMVPTKRTTTPTERTTIPAEKPTVPIEKPMVPTERTTIPTERTTIPTEKPTVPTEKLTVPTEKPIVPTEKPIVPTEKHTIPTEKLTVLTERTTTPTERTTIPTEKPTVPTEKPSVPTEKPTVPTEEPTIPTEKLTVPTERTTTPTKRTTTPTIRTTTPTIRTTTPTERTTTPTIRTTTPTERTTIPTKKTTVPTEKTIIPTERTIAPTTPQPSPTLVPTQPAAVVMPSTSATTVTPRTTIASCPPNAHFERCACPVSCQSPTPNCELFCKPGCVCDPGFLFSGSHCVNASSCDCFYNDNYYKLGTDWFSPNCTEHCHCRPSSRMECQTFKCGTHTVCQLKNGQYGCHPYGSATCSVYGDPHYLTFDGRRFNFMGKCTYILAQPCGNLTGRTQRCLGLGSEVRRAGSSLASPPCLPVSSFGPSFQVGGQRVTLPAIPSRGVFLAPSGRFVELQTAFGLRVRWDGDQQLFVSVPSTFSGKLCGLCGDYDGDSSNDNQKPDGSPAKDEKELGSSWQTSEDADQQCEENQVSPPSCNTALQNTMSGPEFCGQLVAPHGVFEACLPHLRASSFFKSCTFDMCNFQGLQHMLCAHMSALTENCQDAGYTVKPWRGPQFCPLACPRNSRYTLCARLCPDTCHSEFSGRACKDRCVEGCECDPGFVLSGLQCVSRSECGCLDSTAGYVKVGERWFKPGCRQLCICEGNNRTRCVLWRCQAQEFCGQQDGIYGCHAQGSATCTVSGDPHYLTFDGALHHFTGTCTYTLTKPCWLRSLENSFLVSATNEFRGGNLEASYVRAVQVQVFNLRISLIKGRKVTLDGRRVALPLWPAQGRVSIMSSGSFILLYTDFGLQVRYDGDHLVEVTVPSSYAGRLCGLCGNYNNNSLDDILQPDKRPASSSVRLGASWKINELSEPGCFAEGGKPPRCLGKEVADAWRKNCDVLMNPQGPFSQCHRVVAPQSSFSSCLYGQCATKGDTLTLCRSLQAYASLCARAGQALTWRNGTFCPLKCPSGSSYSTCANPCPATCLSLNNPSYCPSTLPCAEGCECQKGHILSGTSCVPLSQCGCTTQRGSYHPVGESWYTDNSCSRLCTCSAHNNISCRQASCKPSQMCWPQDGLIRCRVAGMGVCRIPDTSHYVSFDGSYHAVRGNCTYVLVKICHSTMDLPFFKISGENGKREGQPPAFYLRQVYVDIFNTLVTLKQDQVLINGTRVSLPATTQIRGVRVISRDGYTVLTINIGVQVKFDGRGFLEVEIPKAYYGRTCGVCGNFNDEEEDELMMPSDALALDDVMYVDSWRDKEIDPNCQEDDRKTEAESQEQPSANCRPADLERAQEQCQAAFQAPAWANCATRVVLSPYVRSCTHKLCEFGGLNRAFCESLQAFGAACQAQGIKPPVWRNSSFCPLDCSAHSVYTSCVPSCLPSCQDPEGQCTGAGAPSTCEEGCICEPGYVLSEQQCVARSQCGCRDARGTFLPVGRFRLSSGCSQMCVCTAGAIECRPFTCPSGSQCEPNEDGKDFCQPNSSNLCSVFGDPHYRTFDGLSYRFQGRMTYTLVKTLDVLPDGVEPLVVEGRNKVYPSLTPVFLQEIIVMVYGYTVQLQAELELVVNGQKVSIPYKPNEYLQVTLRGRRLYLVTDFELVVSFNGRNNAVIAMPSTYLGLVRGLCGNYDKNKRNDFMLPNGSFTQNLLVFGNSWEVKAKEGHPRFSRAIREEEEKNEESGFQNVSECSPEQLELVNHTQACGVLVDPQGPFAACHQIVAPGPFQEHCVFDLCAAPGPKEQEELRCQVLSGYAIICQESGATLAGWRDHTHCALPCPANTVYQSCMTPCPASCATLAVPRACDGPCVEGCASLPGYIYSGAQSLPMAHCGCTNNGVYYQQGDSFVTENCSQRCTCASSGVLLCEPLSCRPGEICTLGNLTRGCFRDSPCLQNPCQNDGRCREQGTHFTCECELGYGGDLCTEPRGVPSPKKPEASNRVAILLGMLMPTVLLVPAVTRVSRKRRRRRRPSRERTQSQNRGKRAGTDCAPEQAYKVA", "length": 2470, "header": "tr|F1RMX7-1|A0A5G2QZP6_PIG Computationally mapped isoform of Zonadhesin OS=Sus scrofa OX=9823 GN=ZAN PE=4 SV=4 CANONICAL=A0A5G2QZP6-1" }, "locus": { "chromosome": "3", "start_pos": 8668831, "end_pos": 8638719, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008414.4", "url": "https://www.ensembl.org/id/ENSSSCT00000008414.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008195.4", "url": "https://www.ensembl.org/id/ENSSSCP00000008195.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 618, "start_aa": "Thr", "end_pos": 618, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr618", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 880, "start_aa": "Thr", "end_pos": 880, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr880", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 907, "start_aa": "Thr", "end_pos": 907, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr907", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FML9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FML9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G404-1", "protein_name": "Zonadhesin", "gene_name": "Zan", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLIPAFGGPPLRSPMAPPVWTLMLLLVGAAWGQDQVPSPVWRPNSPDPELMVHTPREDYILSKCDFEDNSRPFCDWSQMSQDDGDWVRTTGPSLTGTSGPPGGYPNGEGYYLHMDPKTFPRGGVARLRSPDIWEQGPLCVHFAFHMFGLSWGAQLRLLLIRGRKHHRPYMLWKHVNTQSPSWMPTTVTVPADHDIPSWLMFEGVRGNTAYLDISLDGLSIQRGTCNRICMSQMCTFDTLNDLCGWSWVPTATGAKWTQKKGATGTLGVGPDEDFSNPSSGYYMLLDSTNARPGQKAVLLSPLSHSSGCLTLSFYYIMHGQGHDEGLFVYATFLGNIRKHSLFSGHPGPDWQAVSVNYTGQGQIQFMVVGVFGNNPEPAIAVDAISIAPCGESFPQCDFEDRNHPFCDWSQMYGDIGHWSWGSKSVPTPISGSPREFPYGGGHYIFFDSVKLSQEGQSARLVSPPFCAPGDICVEFSYHMYGLGKGTTLKLLLGSPAGSSPIPLWNRVGSQSSGWLNSSVTIPKGHQQPMQLFIEATRGTSTAFVVALNFILISHGPCRVLLQTEIPPSPLFPPAGPAVLTVPVLPTEEHTTPTEATTVPIEIATTPMEEITIPTEAATVPIRETIIPTEVTAIPTEVTTPTGEVVTDHMGVTYVSPEETSIPTTMIIPAEATTVSSEEITLATEAITVPTEMVIVSIELGGVTIVVTNIPPAETIPTEVTTVSPEETALLTEVTTVLPEETTVPTEATAVHMEATSVSPQETSVPPEETIPTEVTTVSPEETALLTEVTTVLPEETTVPTEATAVHMEATSVSPQETSVPPEETIPTEVTTVPPEEFILPTEVTTVPTEVTNVLPEDTTVPTEVTTVHMEATNVSPGEISVSPEETTATEVTTISPEEAILPTKVIILPIEEIAVPTEVTIVPTEVTIVPTGETTLPTEVATVPTEVTAVHMEATNVSPEETIHPEETIATDVTTLPTEVATVPTEVTAVHMETTNVSPEETIHPEETIATDVTTLPTEVATVPTEVTAVHMEATNVSPEETIHPEETIATDVTTLPTEVATVPTEVTAVHMEATNVSPEETIHPEETIATDVTTLPTEVATVPTEVTAVHMEATNVSPEETIHPEETIATDVTTLPTEVATVPTEVTAVHMEATNVSPEETIHPEETIATDVTTLPTEVATVPTEVTAVHMEATNVSPEETIHPEETIATDVTTLPTEVATVPTEVTAVHMEATNVSPEETIHPEETIATDVTTLPTEVATVPTEVTAVHMEATNVSPEETIHPEETIATDVTTLPTEVATVPTEVTAVHMEATNVSPEETIHPEEPIATDVTTLPTEVATVPTEVTAVHMEATNVSPEETIHPEETIATDVTTLPTEVATVPTEVTAVHMEATNVSPEETIHPEETIATDVTTVSPEETIATDVTTVYPEVTILLTGVATVPIEVPTVFTEVTTVPIGETTLPTEVPTVLTKVTTVPTEVTTVPTGETTLPTEVTTVTTGKTALPTEVPTVLTEVTGVHTEVTNISPEETSVPPEEIIPTEVTTLSPEETMFPTEVPTVLTEVTTVPTEVTTVLTKETTFPTAMPTVSTEVTNVSPEETSVPHEETIPTEITTVSPEEMVLPTEVTTVPIEVTTVPTEVLTVLTGKITIPTDITIVSTEVTGVHTDMTNVSPEETSIPPEEIIPTEVITFSLEETMFPTEVPTVSTEVAGVHTEVTTPPPEETTIPTEVTIVPPVSIPPEETTTPTEVSTTPPEETTIPTEVTTLLPVSIPPEETTIPTEVTTPPPVSIPPEETTTPTEVSTTPPEETTIPTEVTTVPPVIISPEETTTPTEVTTPPPEETTIPTEVTTVPPVSISPEETTTPTEVTTPPPEETTIPTEVTTVPPVSVPPEETTVHTEVTTVPTEGTTVPPEKTTIPSEETTVSTPETIFLTKQSTVIQTSTACRPPCPSPTLMPIGPSLLKPPVVSVIGMAPTTVNCPPNAHFELCACPASCENPKPSCQYPCIPGCICNPGFLFSNNQCINESSCNCPYDHKYYKPGEEWFSPNCTERCRCLPGSLMECQISQCGTHTICQLKSGQYQCEPYGGATCLVYGDLHFVTFDERHIGFTGTCTYILTETCSNSTDPFFRITASTQERGVDGVSSLGKVFITLQEMTITMDRGRHTLIGDQEVTLPAIPSDGIYVGLSGRFVELKTTFGLRVRWDGDQQLFVTVSSTYSGKLCGFCGNYDGDSSNDNLKSDGMMAYDSEELGQSWQVEKEEDEECLKKKIPPSCDPALVTTMLGPELCGQLVNPSGPFEACLLHLKASSFLDNCVTDMCSFQGLQQKLCAHMSAMTATCQDAGYPVKAWRGPEMCPLVCPKNSRYSLCANPCPDTCHPGSATQTCSDDCVEACECSPGFILSGFECVPASECGCISLQGRYFKVQEQWFNPDCKEICICESHNNIRCKPWKCKAQETCGHKNGILGCHAQGTATCIASGDPHYLTFDGALHHFMGTCTYVLTQPCWPKSQDNNFVVSATNEIRGGNMEVSYVKAVHVQVFDLKISLFKGQKVMVNNQRVVLPVWPSKGRVTIRMSGIFVLLYTNFGLQVRYDGRHLVEVTVPSSYTGSLCGLCGNYNNNSLDDNLRADMKPAVNSLLLGAAWKILEASDPGCFIVGVKASSCQESNVDDTWTRKCAVLMNPVGPFSNCHEVVPPQASFSSCVYDQCGTNGDDLTFCRSLQAYASLCAQAGQVITWRNSSFCPLRCPPRSNYSPCANSCPATCLTLSIPKDCPTLPCVEGCECERGHILSGTTCVPLRECGCSDQDGSYHLLGESWYTEKTCTTLCTCSVPSNITCSPTSCKANHVCLRQDGLLRCAAEVGECHISEDSQIVSFDDHSHPIQEACTYILVKVCHPSMNLPFFTISAKIDMIANSHETFRAYQLYIDIFNFHITLQKNHLVLISLINDSMITLPATTQIPGLSVMTEGVYTIVTIKDEILVKFESNNFLVIKIPATSNGKVCGVCGNFNGEEEDELMTPSDELAENEQEFMESWKDKNIDPNCQKIEEQSVHVEQQEVMHGKCRPIDFEQAQANCQTALQSPAWAHCSSRVPTKPFLLKCMNSFCEFGELFRALCDSLQSFEDSCRNQGLEPPIWRNSSFCPLECPAHSHYTNCLPSCLPSCLDPDSRCEGSGHKVPATCKEGCICQPDYVLNNDKCVLKSQCGCRDGKGVFTPEGKNWISNSCTQNCVCIGGTIECQNFQCPLGAQCRDNEDGSSTCVKISVQCPVHSIYTKCLPPCPPTCSNPDGHCEATSPDIPAICREGCLCQTGFVSDNDKCVPATECACKDTQRGFILAGKTWISEDCTQSCTCVKGTLRCRDFHCPSGTYCRNSTCVKIFLQCPAHSQFTDCLPPCHPSCSDPEGHCEGINTKGPSHCKEGCVCQSGYVLQDDKCVLKIECGCRDTQGGFILAGKNWTSRGCTQSCNCMEGVVRCQHFQCPSGTYCQDIADGTSNCATLQCPAHSSFTNCLPSCLPSCLDPEGHCEGFTTKGPFACKEGCVCEPGYVLLDDKCVPRIECGGCKDAQGVLISADKTWINKGCTQICTCVTGTIHCTNFQCPLGTYCKDIEDGNTNCTKISLQCPPHSLYTHCLPSCLPSCSDPEGLCGGTIQKVASTCREGCVCEPGYVLRNDKCVLKIECDCEDAHGVLIPADTIWINRGCTQTCTCMGGAIQCQNFKCPLDTYCKDIEDGNSNCTNIELHCPAHSHYSNCLPHCQPSCSDPDGHCEGSSTKAPSTCREGCVCEPDYVLNGNKCVLRIECGCKDTQGVLILEDTTWINRGCTRSCTCVGGAIQCQKHHCPSGTYCKDAEGDSSSCAPITLQCPAHSSFTNCLPSCLPSCSDPEGHCEGSTTKGPFACKEGCVCEPGYVLLDDKCVPRIECGGCKDAQGVLIPVDKIWINRGCTQTCTCMGGAIQCRKFQCPSGTYCKGIEDGNSNCTNIPLQCPAHSSFTNCLPSCLPSCSNMNVHCEESRPKALSTCKEGCVCHSGYVLYNEECIRRNRCGCKDGQGAVVPTGETWINKGCTQICTCVTGTIHCRKFQCPLGTYCKDIADGNSNCTNIHEGWQGSEEAVRFGADGHGYWEPNTVPPEDKPTLKCPAHSRYTHCLPSCPPSCSDPEGLCGGTSPKVPSTCKEGCICQLGYVIHMDKCVLRSHCGCKDTQGAFISADKTWISRGCTKSCTCTEGVIQCRNFQCPSGTYCKDSDNGSPNCTKITLQCPVDSQFTDCLPSCLPSCSNHCEVTSPNVPSICKEGCLCNHGFVFSEDACVPRTQCGCKDAHGGIIPAGKTWTSKDCTQTCTCIEGTIQCQNSQCPPETYCKDNGDGSSNCTKITLQCPAHSLFASCLPSCLPSCSDPEGLCGGTSPEVPSTCKEGCVCQSGYVLNSDKCVLRVECDCRDTQGALILAGNTWTSKGCTQSCTCIEGAIQCQNSQCPPGTYCKDSSDGSGSCVEITLQCPAHSLFTDCLPSCLPSCLHPDGLCKGVSPTVPSTCKEGCVCQSGYVLSNNKCILRNQCGCKDAHGVLIPEDKTLISRDCTQSCVCTEGSIQCLVFQCPPGTYCRDSGDGSGTCVKISLQCPANSRYTDCVPLCPPSCSDPEGRCEGPGPTVPSICKEGCLCHPGFVLDWDKCVPRIECGCKDTQGALIPAGKTWIPRGCTQSCTCIGGAVQCQNSECPPGTYCKDNIDGSGTCVKITLQCPAHSNYTDCLPTCLPSCLDPSAHCGEPSPKDPSTCKEGCVCQPGYMLDKDKCVLKVECSCRDNQGAVIPAGETWISKGCTQSCACMGGAVQCQNSQCPPGTYCKDSIDGSSNCTEITLQCPAHSYFTTCLPSCPASCSNLDGSCVESNFKAPFICKEGCICQPGYFLNNDKCVLRIQCGCKDAQGGLIPASRTWISAGCTESCTCVGGNIRCRNFQCPPGTYCKDSSDGSGSCVKITLQCPPHSRFTDCLPACPPSCTALDGQCEGISPKVPSPCTEGCLCQPGYVMHNHKCVLQIHCDCRDAHGGFIPAGKTWISSDCTQSCACVGGTVQCHNFTCPPGTQCQNSVCSKIIQCPVHSHYTACLPSCPPSCFDPEGLCWGTSPRTPSTCKEGCVCQPGYVLNEDKCVLRSHCVCKNNQGVLIPADKSWLTRGCIQNCTCKGGDIHCLNFKCPLGTECKDSVDGNSNCAKIVLQCPAHSYHTNCLPSCIPSCSNVNGRCEFTSLKNPSTCIEGCLCQSGFVFNKDKCVHRTQCGCKDSQGTLIPAGKNWITTGCSQRCTCTAGLVQCHDFECPSGTECQDIEDGNSNCAEITVQCPAHSHYSKCLPSCLPSCSDPDGLCKGTRPKASSTCEEGCVCQSGYVLSNDTCIRSSACTCKNTHGVLIPEGKTWVSRGCTKNCTCKGGTVQCQDFGCPTGSRCIDNKDGNSNCVTYALKCPAHSLYTHCLPSCLPSCSDPEGLCGGTSPEVPSTCKEGCFCRSGYVLHNNKCMLRIHCNCKDSQGSLIQVGQTRISSGCSQICECKKGSFQCQSFKCPSGTQCEENEDGSHNCVSSTMKCPANSLRTNCLPSCLRSCSNPDGHCEGTSHKTPSTCREGCVCRPGYLLDKDTCVRKDQCDCKDIKGDIIPAGKTWISSGCTQSCACTDGVIQCQNFICPSGSHCQHNDDGSSDCAANKLEKCTIFGDPYYHTFDGFTYRFLGRMNYYLIKTLDKLPRGIEPLIMEGRNKISPKGSSTLHEVTTIVYGYKIQLQEGLGVLVNNQKVSVPYNPNEHLRVILRAQRLLLATDFEMVLDFDGKHSAVISLPTTYRGLIRGLCGNYDKDQTNDFMLPSGEVTSNVHVFGNSWEVKVMHAFFRFPRALPEEGGREEEPDLLQSECSPEQTALIGSTQACRVLVDPQGPFAACHQIIAPEPFKQRCISDMCTGWKTKEEEELRCRVLGGYAIICRDAGANMTGWRDQAHCAMTCPANTVYQSCMTPCPATCAKFVTPKVCEGPCVEGCASLPGYIYSDTQSLPVTHCGCTTNGIYYKLGDSFVTNNCSQRCSCASRGILLCEPYGCRGGESCMVANFTRDCFRDSPCLQNPCHNDGRCEERGAAFICHCDFGYGGEFCTEPRDVTTRKKLEASSLVAILPGVLVMVLVPVLLPRVYVYMATRTTMARRRRKGEKLLRRSILRLEDTDVPEPTFKATEF", "length": 6192 }, "evidence": [ { "id": "A0A5G2QZP6", "url": "https://omabrowser.org/oma/group/A0A5G2QZP6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y493-1", "protein_name": "Zonadhesin", "gene_name": "ZAN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADDEDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFAHHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEGTRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSSGKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPGAALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDATSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHYIYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLHCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQCREQGATFTCECEVGYGGGLCMEPRDAPPPRKPASNLVGVLLGLLVPVVVVLLAVTRECIYRTRRKREKTQEGDRLARLVDTDTVLDCAC", "length": 2812 }, "evidence": [ { "id": "A0A5G2QZP6", "url": "https://omabrowser.org/oma/group/A0A5G2QZP6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZP6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZP6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1318, "end_pos": 1320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1493, "end_pos": 1495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1612, "end_pos": 1614, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1708, "end_pos": 1710, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1760, "end_pos": 1762, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1818, "end_pos": 1820, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2007, "end_pos": 2009, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2129, "end_pos": 2131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2286, "end_pos": 2288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2329, "end_pos": 2331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2342, "end_pos": 2344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2471, "end_pos": 2473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2501, "end_pos": 2503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 921, "end_pos": 923, "annotation": "n_glycosylation_sequon" }, { "start_pos": 997, "end_pos": 999, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 2508, "end_pos": 2544, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6" }, { "id": "PS50060", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50060" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MAM", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 204, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP6" }, { "id": "PS51233", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51233" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFD", "eco_id": "ECO_0000259", "start_pos": 963, "end_pos": 1140, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 618, 880, 907 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1318, "end_pos": 1320 }, { "start_pos": 1493, "end_pos": 1495 }, { "start_pos": 1612, "end_pos": 1614 }, { "start_pos": 1708, "end_pos": 1710 }, { "start_pos": 1760, "end_pos": 1762 }, { "start_pos": 1818, "end_pos": 1820 }, { "start_pos": 2007, "end_pos": 2009 }, { "start_pos": 2129, "end_pos": 2131 }, { "start_pos": 2286, "end_pos": 2288 }, { "start_pos": 2329, "end_pos": 2331 }, { "start_pos": 2342, "end_pos": 2344 }, { "start_pos": 2471, "end_pos": 2473 }, { "start_pos": 2501, "end_pos": 2503 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 921, "end_pos": 923 }, { "start_pos": 997, "end_pos": 999 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZQ8-1", "uniprot_ac": "A0A5G2QZQ8", "uniprot_id": "A0A5G2QZQ8_PIG", "mass": { "chemical_mass": 34406.0, "monoisotopic_mass": 34406.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100625390", "type": "recommended", "evidence": [ { "id": "A0A5G2QZQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QZQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100625390", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8", "locus": {} } ], "crossref": [ { "id": "A0A5G2QZQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045772", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045772", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QZQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANSSCVTEFFLLGFSSLGDLQLVLFVIFLCLYLIILSGNITIISVIRLDHSLHTPMYFFLCVLSTSETFYTIVILPKMLINLLSVLRTLSFVSCASQMYFFLGFAVTNSLLLGVMGYDRYAAICQPLHYPILMSWRVCRQLAATCIVTGFLISLLGTSLVFSLPFCGSNRVNHYFCDISPVIRLACAETYINELVIFIGGVLVLVVPLICICISYGFIASAILKISSAEGKRKAFSTCASHLIVVIVHYGCASFVYLRPSAKYTSGKDRLVTVTYTVITPLLNPMVYSLRNKDVQLAIRKMLGKTGFSAL", "length": 311, "header": "tr|A0A5G2QZQ8-1|A0A5G2QZQ8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100625390 PE=3 SV=1 CANONICAL=A0A5G2QZQ8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8/entry#A0A5G2QZQ8-1", "sequence": { "sequence": "MANSSCVTEFFLLGFSSLGDLQLVLFVIFLCLYLIILSGNITIISVIRLDHSLHTPMYFFLCVLSTSETFYTIVILPKMLINLLSVLRTLSFVSCASQMYFFLGFAVTNSLLLGVMGYDRYAAICQPLHYPILMSWRVCRQLAATCIVTGFLISLLGTSLVFSLPFCGSNRVNHYFCDISPVIRLACAETYINELVIFIGGVLVLVVPLICICISYGFIASAILKISSAEGKRKAFSTCASHLIVVIVHYGCASFVYLRPSAKYTSGKDRLVTVTYTVITPLLNPMVYSLRNKDVQLAIRKMLGKTGFSAL", "length": 311, "header": "tr|A0A5G2QZQ8-1|A0A5G2QZQ8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100625390 PE=3 SV=1 CANONICAL=A0A5G2QZQ8-1" }, "locus": { "chromosome": "4", "start_pos": 91743737, "end_pos": 91722270, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102999.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102999.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076369.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076369.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZQ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZQ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZQ8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZU2-1", "uniprot_ac": "A0A5G2QZU2", "uniprot_id": "A0A5G2QZU2_PIG", "mass": { "chemical_mass": 77673.0, "monoisotopic_mass": 77673.0 }, "refseq": {}, "gene_names": [ { "name": "SLCO4C1", "type": "recommended", "evidence": [ { "id": "A0A5G2QZU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2" } ] } ], "protein_names": [ { "name": "Solute carrier organic anion transporter family member", "type": "recommended", "evidence": [ { "id": "A0A5G2QZU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLCO4C1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2", "locus": { "chromosome": "2", "start_pos": 107814844, "end_pos": 107887383, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014182", "url": "https://www.ensembl.org/id/ENSSSCG00000014182" } ] } } ], "crossref": [ { "id": "A0A5G2QZU2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014182", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014182", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11388:SF103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11388:SF103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-879518", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-879518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QZU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGSKGIDNPAFVASSPDTPRRLVPSPSHVEVSVLTRREDSQPQEPQKSPDLPLSSVTTPGSQEGSGPVSQSEFEEGPCGWGNFQPQCFQRCNTPRGFLFHYCLLALTQGIVVNGLVNISISTIEKRYELKSSLTGLISSSYDISFCLLSLFVSYIGERGHKPRWLAFASFMLGLGALVFSLPKFFSGRYQLGSLFEDACLAEKNKAICTASSSSLFKFLYVFILGQLLLGTGGTPLYTLGTAFIDDSVPTHKSSLYIGIGFAMSVLGPAFGYVLGGQLLTVYIDVDSGQSIDVTEDDPRWLGAWWIGFLLSWLLAWSLIIPFSCFPKHLPGTEEIQDGKISQAHQSGRNTDRNFGQSFKDFPAAVKNLMRNTVFMCLVLSTCSEALVATGFATFLPKFVENQFGFSSSSAATLAGSVLVPGAALGQILGGMLVSKFKMTCKNIMKFTLLTTVIALILSLVFLYTTCENAPFAGVSESYNGTGQLGKLTAPCNANCNCLRSYYYPLCGGDGVQYFSPCYAGCTNSISKKHPKVYQNCSCIKRKIEITPTPSSPDFEAKAGKCSVQCKNLPIFLGIFFAAIVFTFMAGTPITVSILRCVNQNQRSLALGIQCMLLRILGTIPGPIIFGIAIDSTCVLWDINKCGIKGACWVYNNIQMAYMFMAISIICKIFTVFFNGCAVFLYKPPPSATDVPFQDQDAVVTTVSLECDLNEAGNKG", "length": 716, "header": "tr|A0A5G2QZU2-1|A0A5G2QZU2_PIG Isoform 1 of Solute carrier organic anion transporter family member OS=Sus scrofa OX=9823 GN=SLCO4C1 PE=3 SV=1 CANONICAL=A0A5G2QZU2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2/entry#A0A5G2QZU2-1", "sequence": { "sequence": "MKGSKGIDNPAFVASSPDTPRRLVPSPSHVEVSVLTRREDSQPQEPQKSPDLPLSSVTTPGSQEGSGPVSQSEFEEGPCGWGNFQPQCFQRCNTPRGFLFHYCLLALTQGIVVNGLVNISISTIEKRYELKSSLTGLISSSYDISFCLLSLFVSYIGERGHKPRWLAFASFMLGLGALVFSLPKFFSGRYQLGSLFEDACLAEKNKAICTASSSSLFKFLYVFILGQLLLGTGGTPLYTLGTAFIDDSVPTHKSSLYIGIGFAMSVLGPAFGYVLGGQLLTVYIDVDSGQSIDVTEDDPRWLGAWWIGFLLSWLLAWSLIIPFSCFPKHLPGTEEIQDGKISQAHQSGRNTDRNFGQSFKDFPAAVKNLMRNTVFMCLVLSTCSEALVATGFATFLPKFVENQFGFSSSSAATLAGSVLVPGAALGQILGGMLVSKFKMTCKNIMKFTLLTTVIALILSLVFLYTTCENAPFAGVSESYNGTGQLGKLTAPCNANCNCLRSYYYPLCGGDGVQYFSPCYAGCTNSISKKHPKVYQNCSCIKRKIEITPTPSSPDFEAKAGKCSVQCKNLPIFLGIFFAAIVFTFMAGTPITVSILRCVNQNQRSLALGIQCMLLRILGTIPGPIIFGIAIDSTCVLWDINKCGIKGACWVYNNIQMAYMFMAISIICKIFTVFFNGCAVFLYKPPPSATDVPFQDQDAVVTTVSLECDLNEAGNKG", "length": 716, "header": "tr|A0A5G2QZU2-1|A0A5G2QZU2_PIG Isoform 1 of Solute carrier organic anion transporter family member OS=Sus scrofa OX=9823 GN=SLCO4C1 PE=3 SV=1 CANONICAL=A0A5G2QZU2-1" }, "locus": { "chromosome": "2", "start_pos": 107887227, "end_pos": 107817450, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067173.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067173.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070391.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070391.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 549, "start_aa": "Thr", "end_pos": 549, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr549", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-879518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-879518", "resource": "Reactome", "description": "Organic anion transport by SLCO transporters" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2" } ], "pmid": "" }, { "name": "sodium-independent organic anion transport", "id": "GO:0043252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043252", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2QZU2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 716, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2QZU2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2QZU2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 486, "end_pos": 541, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QZU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZU2" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 679, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 549 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 536, "end_pos": 538 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2QZV6-1", "uniprot_ac": "A0A5G2QZV6", "uniprot_id": "A0A5G2QZV6_PIG", "mass": { "chemical_mass": 32506.0, "monoisotopic_mass": 32506.0 }, "refseq": {}, "gene_names": [ { "name": "OR51E1", "type": "recommended", "evidence": [ { "id": "A0A5G2QZV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2QZV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OR51E1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6", "locus": { "chromosome": "9", "start_pos": 5473113, "end_pos": 5484468, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014766", "url": "https://www.ensembl.org/id/ENSSSCG00000014766" } ] } } ], "crossref": [ { "id": "ENSSSCG00000014766", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014766", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15222", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15222", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QZV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGPNGNESSATYFILIGLPGLEEAQFWLAFPLCSLYLIAVLGNLTIIYIVRTEHSLHEPMYIFLCMLSGLDVLISTSSMPKMMAIFWFNSTTIQFDACLLQMFAIHSLSGMESTVLLAMAFDRYVAICHPLRHATVLTLPRVTKIGMAAVVRGVALMAPLPVFIKRLPFCSSNVLSHSYCLHQDVMKLACADIRVNIIYGLIVIISAIGMDSLLISLSYLLILKTVLGLTREAQAKAFGTCVSHVCAVFIFYVPFIGLSMVHRFDKRHDSLLPSSWPTPTCLFLLCSTPLSTE", "length": 294, "header": "tr|A0A5G2QZV6-1|A0A5G2QZV6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR51E1 PE=3 SV=1 CANONICAL=A0A5G2QZV6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6/entry#A0A5G2QZV6-1", "sequence": { "sequence": "MVGPNGNESSATYFILIGLPGLEEAQFWLAFPLCSLYLIAVLGNLTIIYIVRTEHSLHEPMYIFLCMLSGLDVLISTSSMPKMMAIFWFNSTTIQFDACLLQMFAIHSLSGMESTVLLAMAFDRYVAICHPLRHATVLTLPRVTKIGMAAVVRGVALMAPLPVFIKRLPFCSSNVLSHSYCLHQDVMKLACADIRVNIIYGLIVIISAIGMDSLLISLSYLLILKTVLGLTREAQAKAFGTCVSHVCAVFIFYVPFIGLSMVHRFDKRHDSLLPSSWPTPTCLFLLCSTPLSTE", "length": 294, "header": "tr|A0A5G2QZV6-1|A0A5G2QZV6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR51E1 PE=3 SV=1 CANONICAL=A0A5G2QZV6-1" }, "locus": { "chromosome": "9", "start_pos": 5476589, "end_pos": 5475708, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016117.4", "url": "https://www.ensembl.org/id/ENSSSCT00000016117.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063785.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063785.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZV6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2QZV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZV6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 294, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 44, "end_pos": 46 }, { "start_pos": 7, "end_pos": 9 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R008-1", "uniprot_ac": "A0A5G2R008", "uniprot_id": "A0A5G2R008_PIG", "mass": { "chemical_mass": 35123.0, "monoisotopic_mass": 35123.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R008", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R008/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R008", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R008#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R008", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R008" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R008", "locus": {} } ], "crossref": [ { "id": "A0A5G2R008", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R008", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014769", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014769", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R008", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R008", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R008-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R008-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGPSYNHAMETPATFILVGIPGLPSSHVWLAVSLSITYVAALLGNSLIVTVIWTDSALQEPMYHLLCVLAAVDMAMASSVVPTMVSIFSSGHSSISFTACFTQMYFVHAATAMETGLLLAMAFDRYVAVCKPLHHKRILTPRVLWGMSVTIAVRAITFMTPLSWMVSQLPFCGSNVVLHSYCEHMAVATLACADPRPSCLYSLIGSSIIVGSDVAFIAASYILILQAVFRLSSKNAQLKALGTCGSHVGVMALYYLPGMASIHVAWLGTHAVPLHTQVLLADLYLIIPPTLNPIIYGLKTNQLRKRTWSLLMRCLLEHSNLGL", "length": 324, "header": "tr|A0A5G2R008-1|A0A5G2R008_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2R008-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R008-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R008/entry#A0A5G2R008-1", "sequence": { "sequence": "MLGPSYNHAMETPATFILVGIPGLPSSHVWLAVSLSITYVAALLGNSLIVTVIWTDSALQEPMYHLLCVLAAVDMAMASSVVPTMVSIFSSGHSSISFTACFTQMYFVHAATAMETGLLLAMAFDRYVAVCKPLHHKRILTPRVLWGMSVTIAVRAITFMTPLSWMVSQLPFCGSNVVLHSYCEHMAVATLACADPRPSCLYSLIGSSIIVGSDVAFIAASYILILQAVFRLSSKNAQLKALGTCGSHVGVMALYYLPGMASIHVAWLGTHAVPLHTQVLLADLYLIIPPTLNPIIYGLKTNQLRKRTWSLLMRCLLEHSNLGL", "length": 324, "header": "tr|A0A5G2R008-1|A0A5G2R008_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2R008-1" }, "locus": { "chromosome": "9", "start_pos": 5516377, "end_pos": 5515406, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016120.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016120.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070451.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070451.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R008", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R008" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R008", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R008" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R008", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R008" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R008", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R008" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R008-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 324, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R008-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R008" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R008", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R008" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 297, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R020-1", "uniprot_ac": "A0A5G2R020", "uniprot_id": "A0A5G2R020_PIG", "mass": { "chemical_mass": 103014.0, "monoisotopic_mass": 103014.0 }, "refseq": { "ac": "XP_020945964", "name": "guanylate-binding protein 6-like isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945964" }, "gene_names": [ { "name": "LOC102161784", "type": "recommended", "evidence": [ { "id": "A0A5G2R020", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020" } ] }, { "name": "LOC102161784", "type": "synonym", "evidence": [ { "id": "XP_020945964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945964" } ] } ], "protein_names": [ { "name": "GB1/RHD3-type G domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R020", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020/entry#names_and_taxonomy" } ] }, { "name": "guanylate-binding protein 6-like isoform X3", "type": "synonym", "evidence": [ { "id": "XP_020945964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945964" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R020", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC102161784", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020", "locus": {} } ], "crossref": [ { "id": "A0A5G2R020", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R020", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000030801", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000030801", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01851", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01851", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "102161784", "url": "https://www.ncbi.nlm.nih.gov/gene/102161784", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02263", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02263", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020945964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945964", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R020", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R020-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEERRERERTSTAEQDKRETSGGEKVLLKQHIKKLQHKLVNQENVFQGFRAKMTLEIRERKKLLRNMDERIEAIESFLGITKKRKKCCVKNGDPLRDAEKSPAGAGEPANLEAAQREKELLLQKMMELERRLDDHERILEELRGRMTDGGREMKTTSAGDKGEASAFPGREKELLEQHAKALQQDLEDQEEAFRRFRAQMIEEIREIETAQRQMDERIKILEEILLGYQVAMASALNMTDPICLIENNNELLSVNQEALEILEKISQPVVVVAIVGLYRTGKSYLMNRLAGRNHGFRVGSTVQSETKGIWMWCVPHPSKPDRTLVLLDTEGLGDVEKGDSKNDSWIFALAVLLSSVFVYNSTNTINHQALEQLHYVTELTELIRTKSSSENDGVEDCTEFVSFFPDFIWIVRDFTLDLKLHGHPVTEDEYLENALKLIPGNNPKAQISNLPRECIRNFFPKRKCFVFDRPTDKKNLLASIENVSEDQLDPDFLEQANNFCSYIFTNAKTKTLSDGIPVTGKRLGILVVAYVDAINTGDVPCLENAVATLAQLENSAAMQKAADHYSEQMAQRLDLPADTYLELLEVHADCECEAIAVFMEHSFKDDTQEFQKMLVEIIKNKKEGFVLQNEEASAKYCQEKLDQLSETLVECISAGMFSVPGGHELYRRAKQRLEWDYCHVLRKGVQADKVLQRFLQAQVATEKSILQTDKALTDGQKAIAEERARKEAAEKAQERLKQELLNQKLQEQEQQLAAQKGSFQENIDQLRKKLERELEYRLREQNMMLERKLKTQEVLLGKVFERRSEKMNAEIDHLRNIIAGTDSDDTHWVVKAFVNFVIRIISAIFPRNTSTLFVRNTMYVFWLRGFFWGAFFHFLFFWVCNLIFYICFYYYS", "length": 893, "header": "tr|A0A5G2R020-1|A0A5G2R020_PIG Isoform 1 of GB1/RHD3-type G domain-containing protein OS=Sus scrofa OX=9823 GN=LOC102161784 PE=3 SV=1 CANONICAL=A0A5G2R020-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R020-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020/entry#A0A5G2R020-1", "sequence": { "sequence": "MTEERRERERTSTAEQDKRETSGGEKVLLKQHIKKLQHKLVNQENVFQGFRAKMTLEIRERKKLLRNMDERIEAIESFLGITKKRKKCCVKNGDPLRDAEKSPAGAGEPANLEAAQREKELLLQKMMELERRLDDHERILEELRGRMTDGGREMKTTSAGDKGEASAFPGREKELLEQHAKALQQDLEDQEEAFRRFRAQMIEEIREIETAQRQMDERIKILEEILLGYQVAMASALNMTDPICLIENNNELLSVNQEALEILEKISQPVVVVAIVGLYRTGKSYLMNRLAGRNHGFRVGSTVQSETKGIWMWCVPHPSKPDRTLVLLDTEGLGDVEKGDSKNDSWIFALAVLLSSVFVYNSTNTINHQALEQLHYVTELTELIRTKSSSENDGVEDCTEFVSFFPDFIWIVRDFTLDLKLHGHPVTEDEYLENALKLIPGNNPKAQISNLPRECIRNFFPKRKCFVFDRPTDKKNLLASIENVSEDQLDPDFLEQANNFCSYIFTNAKTKTLSDGIPVTGKRLGILVVAYVDAINTGDVPCLENAVATLAQLENSAAMQKAADHYSEQMAQRLDLPADTYLELLEVHADCECEAIAVFMEHSFKDDTQEFQKMLVEIIKNKKEGFVLQNEEASAKYCQEKLDQLSETLVECISAGMFSVPGGHELYRRAKQRLEWDYCHVLRKGVQADKVLQRFLQAQVATEKSILQTDKALTDGQKAIAEERARKEAAEKAQERLKQELLNQKLQEQEQQLAAQKGSFQENIDQLRKKLERELEYRLREQNMMLERKLKTQEVLLGKVFERRSEKMNAEIDHLRNIIAGTDSDDTHWVVKAFVNFVIRIISAIFPRNTSTLFVRNTMYVFWLRGFFWGAFFHFLFFWVCNLIFYICFYYYS", "length": 893, "header": "tr|A0A5G2R020-1|A0A5G2R020_PIG Isoform 1 of GB1/RHD3-type G domain-containing protein OS=Sus scrofa OX=9823 GN=LOC102161784 PE=3 SV=1 CANONICAL=A0A5G2R020-1" }, "locus": { "chromosome": "4", "start_pos": 127257068, "end_pos": 127230581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075168.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075168.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069735.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069735.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R020", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R020", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R020", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R020", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020" } ], "pmid": "" }, { "name": "cellular response to type II interferon", "id": "GO:0071346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071346", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R020", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020" } ], "pmid": "" }, { "name": "defense response to protozoan", "id": "GO:0042832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042832", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R020", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R020", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R020-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 893, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R020-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R020" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R020", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R020" }, { "id": "PS51715", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51715" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GB1/RHD3-type G", "eco_id": "ECO_0000259", "start_pos": 267, "end_pos": 509, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 238, "end_pos": 240 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 849, "end_pos": 851 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R066-1", "uniprot_ac": "A0A5G2R066", "uniprot_id": "A0A5G2R066_PIG", "mass": { "chemical_mass": 35185.0, "monoisotopic_mass": 35185.0 }, "refseq": { "ac": "XP_013845622", "name": "olfactory receptor 5H2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845622" }, "gene_names": [ { "name": "LOC110256446", "type": "recommended", "evidence": [ { "id": "A0A5G2R066", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066" } ] }, { "name": "LOC100514797", "type": "synonym", "evidence": [ { "id": "XP_013845622", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845622" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R066", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5H2-like", "type": "synonym", "evidence": [ { "id": "XP_013845622", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845622" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R066", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R066", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110256446", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066", "locus": {} } ], "crossref": [ { "id": "A0A5G2R066", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R066", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514797", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514797", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PLAFRYV", "url": "https://omabrowser.org/oma/group/PLAFRYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R066", "url": "https://www.orthodb.org/?gene=A0A5G2R066", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013845622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845622", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R066", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R066-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METKNATELTEFVLTGLKYQSEWQIPLFLLFLIIYLITLIGNLGLIALICNDPHLHSPMYLFLGNLAFVDTWLSSTVTPNMLVNFFSKSKMISLSECKIQFFSFAICATTECFLLATMAYDRYVAICKPLLYPVIMTNRLCIRLLILSFLGGLSHAIIHNVFLLRLTFCNSIIIHHFYCDIIPLFKISCTDPSINYMMVLIFAGIIQIFTISVVLASYTLVLFTILKKKSMQGIRKTFSTCGAHLLSVSLYYGPLLFMYVLPGSAEENDQDMMDSLFYAVIIPFLNPIIYSLRNKKVIDSVTKMLKRNV", "length": 309, "header": "tr|A0A5G2R066-1|A0A5G2R066_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110256446 PE=3 SV=1 CANONICAL=A0A5G2R066-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R066-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066/entry#A0A5G2R066-1", "sequence": { "sequence": "METKNATELTEFVLTGLKYQSEWQIPLFLLFLIIYLITLIGNLGLIALICNDPHLHSPMYLFLGNLAFVDTWLSSTVTPNMLVNFFSKSKMISLSECKIQFFSFAICATTECFLLATMAYDRYVAICKPLLYPVIMTNRLCIRLLILSFLGGLSHAIIHNVFLLRLTFCNSIIIHHFYCDIIPLFKISCTDPSINYMMVLIFAGIIQIFTISVVLASYTLVLFTILKKKSMQGIRKTFSTCGAHLLSVSLYYGPLLFMYVLPGSAEENDQDMMDSLFYAVIIPFLNPIIYSLRNKKVIDSVTKMLKRNV", "length": 309, "header": "tr|A0A5G2R066-1|A0A5G2R066_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110256446 PE=3 SV=1 CANONICAL=A0A5G2R066-1" }, "locus": { "chromosome": "13", "start_pos": 161449676, "end_pos": 161448750, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083570.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083570.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069780.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069780.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R066", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514797", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514797", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NHG9-1", "protein_name": "Olfactory receptor 5H14", "gene_name": "OR5H14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEENATLLTEFVLTGFLYQPQWKIPLFLAFLVIYLITIMGNLGLIAVIWKDPHLHIPMYLLLGNLAFVDALLSSSVTLKMLINFLAKSKMISLSECKIQLFSFAISVTTECFLLATMAYDRYVAICKPLLYPAIMTNGLCIRLLILSYVGGLLHALIHEGFLFRLTFCNSNIIQHFYCDIIPLLKISYTDSSINFLMVFIFAGSIQVFTIGTVLISYIFVLYTILKKKSVKGMRKAFSTCGAHLLSVSLYYGPLAFMYMGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKRNDV", "length": 310 }, "evidence": [ { "id": "A0A5G2R066", "url": "https://omabrowser.org/oma/group/A0A5G2R066/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4A2H3-1", "protein_name": "Olfactory receptor", "gene_name": "Or5h17b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKKNETLWSEFILTGLTCQPQWKTPLFLMFLVIYLMTIVGNLGLITLIWNDPHLHIPMYLFLSNLAFVDTWLSSTVTPKMLFNLLDKGKVISIAECMTQFFSFAISVTTECFLLAAMAYDRYAAICNPLLYPVVMTNRLCIRLLALSFLGGFLHAVIHESFLSRLTFCNSNILYHFYCDVIPLLKISCTDPSLNYLMIFIFSGSIQVFTIMIVLMSYTFVLFTILKKKSDKGVRKALSTCGAHLLSVSLYYGPLLFMYVLPASSEVDAQDMILSLFYTVIVPVLNPMIYSLRNKQVIDSLKKMLKIMG", "length": 309 }, "evidence": [ { "id": "A0A5G2R066", "url": "https://omabrowser.org/oma/group/A0A5G2R066/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R066", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R066", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R066", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R066", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R066-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R066-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R066" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R066", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R066" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0B8-1", "uniprot_ac": "A0A5G2R0B8", "uniprot_id": "A0A5G2R0B8_PIG", "mass": { "chemical_mass": 34775.0, "monoisotopic_mass": 34775.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R0B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0B8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0B8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8", "locus": {} } ], "crossref": [ { "id": "A0A5G2R0B8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0B8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050809", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050809", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15416", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15416", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R0B8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSLGEGNHTAVREFILLGLTNDPTLQSILFVIILCIYLVTICGNLSTIILIRLSPQLHHPMYFFLSHLAFVDMGFSSSVTPNMLVNFLVERNTISYPGCAVQLGSGAFFGSTECFLLAAMAYDRFVAICNPLLYSTKMSTQVCVQLLTVAYMGGFLNACSITISFFFLLFCGPNRVNHFFCDFAPLLELSCSDFTVPAVVPSFIIGSIIVVTVVVIATSYIYILITVLKMPSTEGRHKAFSTCTSHLTAVTLFYGTITFIYVMPKSSYSTDQNKVVSVFYMVVIPMLNPLIYSLRNKEVKGALKRQLGRKTFS", "length": 314, "header": "tr|A0A5G2R0B8-1|A0A5G2R0B8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R0B8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R0B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8/entry#A0A5G2R0B8-1", "sequence": { "sequence": "MDSLGEGNHTAVREFILLGLTNDPTLQSILFVIILCIYLVTICGNLSTIILIRLSPQLHHPMYFFLSHLAFVDMGFSSSVTPNMLVNFLVERNTISYPGCAVQLGSGAFFGSTECFLLAAMAYDRFVAICNPLLYSTKMSTQVCVQLLTVAYMGGFLNACSITISFFFLLFCGPNRVNHFFCDFAPLLELSCSDFTVPAVVPSFIIGSIIVVTVVVIATSYIYILITVLKMPSTEGRHKAFSTCTSHLTAVTLFYGTITFIYVMPKSSYSTDQNKVVSVFYMVVIPMLNPLIYSLRNKEVKGALKRQLGRKTFS", "length": 314, "header": "tr|A0A5G2R0B8-1|A0A5G2R0B8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R0B8-1" }, "locus": { "chromosome": "9", "start_pos": 1797349, "end_pos": 1796408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083350.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083350.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070594.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070594.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0B8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0B8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0B8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0B8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0B8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0B8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0B8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0B8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0B8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 293, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0G6-1", "uniprot_ac": "A0A5G2R0G6", "uniprot_id": "A0A5G2R0G6_PIG", "mass": { "chemical_mass": 100296.0, "monoisotopic_mass": 100296.0 }, "refseq": {}, "gene_names": [ { "name": "XAB2", "type": "recommended", "evidence": [ { "id": "A0A5G2R0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" } ] } ], "protein_names": [ { "name": "Pre-mRNA-splicing factor SYF1", "type": "recommended", "evidence": [ { "id": "A0A5G2R0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6/entry#names_and_taxonomy" } ] }, { "name": "Pre-mRNA-splicing factor syf1", "type": "synonym", "evidence": [ { "id": "A0A5G2R0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6/entry#names_and_taxonomy" } ] }, { "name": "XPA-binding protein 2", "type": "synonym", "evidence": [ { "id": "A0A5G2R0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6#function" }, { "database": "UniProtKB", "id": "ARBA00056944", "url": "https://www.uniprot.org/uniprotkb/ARBA00056944#function" }, { "database": "UniProtKB", "id": "F1SCH5", "url": "https://www.uniprot.org/uniprotkb/F1SCH5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "XAB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6", "locus": { "chromosome": "2", "start_pos": 71530929, "end_pos": 71521081, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013582", "url": "https://www.ensembl.org/id/ENSSSCG00000013582" } ] } } ], "crossref": [ { "id": "A0A5G2R0G6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0G6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013582", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013582", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100525328", "url": "https://www.ncbi.nlm.nih.gov/gene/100525328", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525328", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525328", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IWYNYLR", "url": "https://omabrowser.org/oma/group/IWYNYLR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1SCH5", "url": "https://www.orthodb.org/?gene=F1SCH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11246:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11246:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23220", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23220", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23231", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23231", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23233", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23233", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6781823", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6781823", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6782135", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782135", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6782210", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SCH5", "url": "https://www.uniprot.org/uniprotkb/F1SCH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SCH5-1", "url": "https://www.uniprot.org/uniprotkb/F1SCH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QIVSSRILRGERIDQSPGIWEEEDLPYEEEIMRNQFSVKCWLRYIEFKQGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVSFKQVDDLASVWCECGELELRHENYDQALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYERATRAVEPSQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIREMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPSRAQSKILFVRSDASREELAELAQRANPEEIELGEDEDEDEMDLEPNEVRLEQQSVPAAVFGSLKED", "length": 858, "header": "tr|A0A5G2R0G6-1|A0A5G2R0G6_PIG Isoform 1 of Pre-mRNA-splicing factor SYF1 OS=Sus scrofa OX=9823 GN=XAB2 PE=1 SV=1 CANONICAL=A0A5G2R0G6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R0G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6/entry#A0A5G2R0G6-1", "sequence": { "sequence": "QIVSSRILRGERIDQSPGIWEEEDLPYEEEIMRNQFSVKCWLRYIEFKQGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVSFKQVDDLASVWCECGELELRHENYDQALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYERATRAVEPSQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIREMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPSRAQSKILFVRSDASREELAELAQRANPEEIELGEDEDEDEMDLEPNEVRLEQQSVPAAVFGSLKED", "length": 858, "header": "tr|A0A5G2R0G6-1|A0A5G2R0G6_PIG Isoform 1 of Pre-mRNA-splicing factor SYF1 OS=Sus scrofa OX=9823 GN=XAB2 PE=1 SV=1 CANONICAL=A0A5G2R0G6-1" }, "locus": { "chromosome": "2", "start_pos": 71530408, "end_pos": 71522079, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072931.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072931.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070602.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070602.1" } ] } }, { "isoform_ac": "F1SCH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6/entry#F1SCH5-1", "sequence": { "sequence": "MVVMARLSRTERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFKQGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVSFKQVDDLASVWCECGELELRHENYDQALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYERATRAVEPSQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIREMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPSRAQSKILFVRSDASREELAELAQRANPEEIELGEDEDEDEMDLEPNEVRLEQQSVPAAVFGSLKED", "length": 855, "header": "tr|F1SCH5-1|A0A5G2R0G6_PIG Computationally mapped isoform of Pre-mRNA-splicing factor SYF1 OS=Sus scrofa OX=9823 GN=XAB2 PE=1 SV=2 CANONICAL=A0A5G2R0G6-1" }, "locus": { "chromosome": "2", "start_pos": 71530408, "end_pos": 71521111, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014834.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014834.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014433.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014433.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SCH5", "url": "https://www.uniprot.org/uniprotkb/F1SCH5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525328", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525328", "resource": "KEGG Pathway" }, { "id": "R-SSC-6781823", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6781823", "resource": "Reactome", "description": "Formation of TC-NER Pre-Incision Complex" }, { "id": "R-SSC-6782135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782135", "resource": "Reactome", "description": "Dual incision in TC-NER" }, { "id": "R-SSC-6782210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782210", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in TC-NER" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1Z9G2-1", "protein_name": "Pre-mRNA-splicing factor syf1 homolog", "gene_name": "fand", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVTKTIKSLNLEINFEVEDVPYEEEILRNAYSVKHWLRYIDHKAKAPNNGVNMVYERALKELPGSYKIWHNYLRTRRKQVRGKIPTDPMYEEVNSAFERALVFMHKMPRIWMDYGAFMTSQCKITRTRHVFDRALRALPITQHGRIWPLYLQFVRRFEMPETALRVYRRYLKLFPEDTEEYVDYLQEADRLDEAAQQLAHIVDNEHFVSKHGKSNHQLWNELCDLISKNPHKVHSLNVDAIIRGGLRRYTDQLGHLWNSLADYYVRSGLFDRARDIYEEAIQTVTTVRDFTQVFDEYAQFEELSLNRRMEQVAANEAATEEDDIDVELRLSRFEYLMERRLLLLNSVLLRQNPHNVHEWHKRVTLYEDKPAEIISTYTEAVQTVQPKQAVGKLHTLWVEFAKFYEANGQVEDARVVFERGTEVEYVKVEDLAAVWCEWAEMELRQQQFEAALKLMQRATAMPKRKIAYYDDTETVQARLHRSLKVWSMYADLEESFGTFKTCKAVYERIIDLKICTPQIIINYGMFLEEHNYFEEAYRAYEKGISLFKWPNVYDIWNSYLTKFLERYGGTKLERARDLFEQCLDQCPPEHAKYFYLLYAKLEEEHGLARHAMSVYDRATSAVKEDEMFDMYNIFIKKAAEIYGLPRTREIYEKAIESLPEQNMRHMCVKFAELETKLGEVDRARAIYAHCSQVCDPRITADFWQTWKEFEVRHGNEDTMREMLRIKRSVQATYNTQVNMMAAQFLSTNNGAAADAGAGAGPDAMRLLEEKARQAAAESKQKPIEKAASNIMFVRGETQGGAKDKKDTVVNPDEIDIGDSDEDDEEEDDDEENEMTNENQASAAVTKTDEEGLVMKKLRFEQKAIPAKVFGSLKPSNQGDSDGE", "length": 883 }, "evidence": [ { "id": "A0A5G2R0G6", "url": "https://omabrowser.org/oma/group/A0A5G2R0G6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "G3HWW6-1", "protein_name": "Pre-mRNA-splicing factor SYF1", "gene_name": "Xab2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVVMARVPRPERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFKQGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAVRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALKLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYDRATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIREMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPPRAQNKIFFVRSDASREELAELAQQANPEEIQLGEEEDEDEMDLEPNEVRLEQQSVPAAVFGSLKED", "length": 855 }, "evidence": [ { "id": "A0A5G2R0G6", "url": "https://omabrowser.org/oma/group/A0A5G2R0G6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q04048-1", "protein_name": "Pre-mRNA-splicing factor SYF1", "gene_name": "SYF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSAYIAMKGVITNVDENIRNDEDVAFEYEIQKTPQNILTWKRYIEYWKEEGRTDKQIRWLYERFCSQFVTDTSIWEDYIRWESTKEVVETSRIFWLFQRCLKSCVRDCDRICLSYLELAIEQYDLAMIRHALASSLMKMEREMHRKVWDPVIKFVEEKVLPLTQLDSTQEDEEESTDEAELINVLLVKGFTKGGFISEEISENGSRGDIWSSHILERYLKVAPQQKRNESLATLALTRDNITIKSVYEKYLPQDENSGKYLPSSELPFELNFNYLASLEKLGLDNQYEEFMRQMNGIYPDKWLFLILSLAKYYISRGRLDSCGDLLKKSLQQTLRYSDFDRIYNFYLLFEQECSQFILGKLKENDSKFFNQKDWTEKLQAHMATFESLINLYDIYLNDVALRQDSNLVETWMKRVSLQKSAAEKCNVYSEAILKIDPRKVGTPGSFGRLWCSYGDLYWRSNAISTARELWTQSLKVPYPYIEDLEEIYLNWADRELDKEGVERAFSILEDALHVPTNPEILLEKYKNGHRKIPAQTVLFNSLRIWSKYIDYLEAYCPKDANSSDKIFNKTKMAYNTVIDLRLITPAMAENFALFLQNHYEVMESFQVYEKTIPLFPPEIQYELWIEYLEVATSHQLSSLSPEHIRFLFEKALKNLCSNGIDCKTIFIAYSVFEERISGLISKSIEILRRGAVIGTVSVSTHLESRLQLWRMCISKAESTLGPSVTRELYQECIQILPNSKAVEFVIKFSDFESSIGETIRAREILAYGAKLLPPSRNTELWDSFEIFELKHGDKETYKDMLKMKKVLESNMLIDSASVSHEEGNINFVAAATSHAPNSHTLTQSTSSYSINPDEIELDI", "length": 859 }, "evidence": [ { "id": "A0A5G2R0G6", "url": "https://omabrowser.org/oma/group/A0A5G2R0G6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54Z08-1", "protein_name": "Pre-mRNA-splicing factor SYF1", "gene_name": "xab2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPSINENEDIINKLKMSTITDDIIIQPSIDDLPYEEDVSKNPYSVNCWLRYLEFKQGSPQKQRNYIYERAIRELPRSYKIWHQYLLERTLAIRGKCILENSFEAVNTLFERSLVFLDKMPRIWIEYCEFLMIQEKITLTRKTFDRALIALPVTQHYRIWNEYTKFILKRSIPSLTCIRVYKRYLKIQPEKVEEYIEYLIKIKEWQEVVNQLIKLLDNVKFKSIKGKSRHDHWLQLCEILSSYPKQITGVDVDSVIRSGIGKFSDQIGKLWCYLSDYYIQLAQFEKARDIFEEALTSVGTARDFSFIWESYTQFEDSLIAAKQEILEEDPSEDNLLEFDIIIERYENLIQRQPLLLNSVMLKQNPNNVQEWLKRVNLYSNPTPNVKMIIQTFTDSIKSIDPQLAKGKLSTIYSTFAHFYEQNNKLSQARLIFENSLTVNFKTIDDLSTLYCDYAEMELKHRNYEKAIEILKRGTVSPKKQNTIIEENEPVQKRLFKSIKIWTFYVDLEESFGTFHNTKSIYEKMIQLKVVTPQIILNFAKYLEENKYFEDMFKAYEHGVQLFLFPHVQDIWITYLTKFIQRYAGMKLERTRDLFEQVLSKVPPKESIIFYLMYANFEEQYGLARHSMAVYDRAAKSVDKEDRFKMYLLYIHRASEFFGVNQTREIFSKAIEQLPDQYVRDMCLKFADMEKKYGEIDRARSIYIHGSQFSDPRTSMFYWNTWSDFEKLHGNEDTFKEMLRIRRSVQASYITQNPTLALLNKLNNKDDKDDKNQQQKQQQQQQEKQQQQQQQQQQASTLTKSKPVTVSLPETIQYNKKIENDDEINLDDDEEEEEEEDQLAIKAFPKTLLKII", "length": 850 }, "evidence": [ { "id": "A0A5G2R0G6", "url": "https://omabrowser.org/oma/group/A0A5G2R0G6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q99PK0-1", "protein_name": "Pre-mRNA-splicing factor SYF1", "gene_name": "Xab2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVMARVPRPERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFKQGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALKLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFISRYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYDRATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIREMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPPRAQSKIFFVRSDASREELAELAQQANPEEIQLGEDEDEDEMDLEPNEVRLEQQSVPAAVFGSLKED", "length": 855 }, "evidence": [ { "id": "A0A5G2R0G6", "url": "https://omabrowser.org/oma/group/A0A5G2R0G6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DCD2-1", "protein_name": "Pre-mRNA-splicing factor SYF1", "gene_name": "Xab2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVVMARVPRSERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFKQGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALKLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFISRYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYDRATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIREMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPPRAQSKIFFVRSDASREELAELAQQANPEEIQLGEDEDEDEMDLEPNEVRLEQQSVPAAVFGSLKED", "length": 855 }, "evidence": [ { "id": "A0A5G2R0G6", "url": "https://omabrowser.org/oma/group/A0A5G2R0G6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HCS7-1", "protein_name": "Pre-mRNA-splicing factor SYF1", "gene_name": "XAB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVMARLSRPERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFKQGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYERATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIKEMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPLRAQSKILFVRSDASREELAELAQQVNPEEIQLGEDEDEDEMDLEPNEVRLEQQSVPAAVFGSLKED", "length": 855 }, "evidence": [ { "id": "A0A5G2R0G6", "url": "https://omabrowser.org/oma/group/A0A5G2R0G6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LKU3-1", "protein_name": "Tetratricopeptide repeat (TPR)-like superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAISKDLYPSQEDLLYEEELLRNQFSLKLWWRYLIAKAESPFKKRFIIYERALKALPGSYKLWYAYLRERLDIVRNLPVTHPQYDSLNNTFERGLVTMHKMPRIWVMYLQTLTVQQLITRTRRTFDRALCALPVTQHDRIWEPYLVFVSQNGIPIETSLRVYRRYLMYDPSHIEEFIEFLVKSERWQESAERLASVLNDDKFYSIKGKTKHKLWLELCELLVHHANVISGLNVDAIIRGGIRKFTDEVGMLWTSLADYYIRKNLLEKARDIYEEGMMKVVTVRDFSVIFDVYSRFEESTVAKKMEMMSSSDEEDENEENGVEDDEEDVRLNFNLSVKELQRKILNGFWLNDDNDVDLRLARLEELMNRRPALANSVLLRQNPHNVEQWHRRVKIFEGNAAKQILTYTEAVRTVDPMKAVGKPHTLWVAFAKLYENHKDLVNTRVIFDKAVQVNYKTVDHLASVWCEWAEMELRHKNFKGALELMRRATAVPTVEVRRRVAADGNEPVQMKLHRSLRLWSFYVDLEESLGTLESTRAVYEKILDLRIATPQIIMNYAFLLEENKYFEDAFKVYERGVKIFKYPHVKDIWVTYLTKFVKRYGKTKLERARELFEHAVSMAPSDAVRTLYLQYAKLEEDYGLAKRAMKVYEEATKKVPEGQKLEMYEIYISRAAEIFGVPRTREIYEQAIESGLPHKDVKIMCIKFAELERSLGEIDRARALYKYSSQFADPRSDPEFWNKWHEFEVQHGNEDTYREMLRIKRSVSASYSQTHFILPENMMQKDKLLDVEDAKGELKRAGLPEDEMAALERQLLSTTTPTEPAKDGGRRVGFVSAGVISQSGENEGKPVTGNGEDIELPDESDDESDGDDHVEISQKEVPAAVFGGLARKRDEDGEEAGEDGAAQKLGALERIKRQKLNQ", "length": 917 }, "evidence": [ { "id": "A0A5G2R0G6", "url": "https://omabrowser.org/oma/group/A0A5G2R0G6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "generation of catalytic spliceosome for first transesterification step", "id": "GO:0000349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000349", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" } ], "pmid": "" }, { "name": "transcription-coupled nucleotide-excision repair", "id": "GO:0006283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006283", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" } ], "pmid": "" }, { "name": "post-mRNA release spliceosomal complex", "id": "GO:0071014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071014", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" } ], "pmid": "" }, { "name": "Prp19 complex", "id": "GO:0000974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000974", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0G6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 858, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0G6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0G6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" }, { "id": "PF23220", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23220" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pre-mRNA-splicing factor SYF1 central HAT repeats", "eco_id": "ECO_0000259", "start_pos": 184, "end_pos": 388, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" }, { "id": "PF23233", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23233" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 181, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G6" }, { "id": "PF23231", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23231" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats", "eco_id": "ECO_0000259", "start_pos": 390, "end_pos": 777, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 555, "end_pos": 557 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0H5-1", "uniprot_ac": "A0A5G2R0H5", "uniprot_id": "A0A5G2R0H5_PIG", "mass": { "chemical_mass": 35606.0, "monoisotopic_mass": 35606.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110258725", "type": "recommended", "evidence": [ { "id": "A0A5G2R0H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R0H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0H5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0H5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110258725", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5", "locus": {} } ], "crossref": [ { "id": "A0A5G2R0H5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0H5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044893", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044893", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15911", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15911", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242:SF378", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242:SF378", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R0H5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METVSIGNRTITEFVLLGFYDIADLHLLFFTVFTLVYTSIIIGNMLIIVAVVRSQKLHTPMYFFLANLSFLEILYTSTVVPKMLEGFLQEAAISVAACLLQFFIFGSLATAECFLLAVMAYDRYLAICYPLRYPLLMGPRWCLGLVLIAWLSGFMVDGLVVALMAQLRFCGPNHIDHFYCDFMSLMSLACSDPSIARMTTFILSVVCLTVPFGLILTSYAWIVVAVLRVPSGARRWKAFSTCSSHLAVVSTFYGTLMVLYIAPSAVHSQLLSKVFALLYTVVTPLFNPVIYTLRNREVHQALRRLKQTETIEEGWW", "length": 316, "header": "tr|A0A5G2R0H5-1|A0A5G2R0H5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258725 PE=3 SV=1 CANONICAL=A0A5G2R0H5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R0H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5/entry#A0A5G2R0H5-1", "sequence": { "sequence": "METVSIGNRTITEFVLLGFYDIADLHLLFFTVFTLVYTSIIIGNMLIIVAVVRSQKLHTPMYFFLANLSFLEILYTSTVVPKMLEGFLQEAAISVAACLLQFFIFGSLATAECFLLAVMAYDRYLAICYPLRYPLLMGPRWCLGLVLIAWLSGFMVDGLVVALMAQLRFCGPNHIDHFYCDFMSLMSLACSDPSIARMTTFILSVVCLTVPFGLILTSYAWIVVAVLRVPSGARRWKAFSTCSSHLAVVSTFYGTLMVLYIAPSAVHSQLLSKVFALLYTVVTPLFNPVIYTLRNREVHQALRRLKQTETIEEGWW", "length": 316, "header": "tr|A0A5G2R0H5-1|A0A5G2R0H5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258725 PE=3 SV=1 CANONICAL=A0A5G2R0H5-1" }, "locus": { "chromosome": "AEMK02000223.1", "start_pos": 57674, "end_pos": 56727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087405.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087405.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069890.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069890.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0H5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0H5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0H5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0H5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0H5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 316, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0H5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0H5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0H5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 67, "end_pos": 69 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0K1-1", "uniprot_ac": "A0A5G2R0K1", "uniprot_id": "A0A5G2R0K1_PIG", "mass": { "chemical_mass": 35902.0, "monoisotopic_mass": 35902.0 }, "refseq": { "ac": "XP_020942030", "name": "olfactory receptor 7A17-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942030" }, "gene_names": [ { "name": "LOC110259901", "type": "recommended", "evidence": [ { "id": "A0A5G2R0K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1" } ] }, { "name": "LOC110259901", "type": "synonym", "evidence": [ { "id": "XP_020942030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942030" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R0K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7A17-like", "type": "synonym", "evidence": [ { "id": "XP_020942030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942030" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0K1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0K1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259901", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1", "locus": {} } ], "crossref": [ { "id": "A0A5G2R0K1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0K1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045912", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045912", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110259901", "url": "https://www.ncbi.nlm.nih.gov/gene/110259901", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110259901", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259901", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R0K1", "url": "https://www.orthodb.org/?gene=A0A5G2R0K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020942030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942030", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R0K1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPWNLTGVSEFILLGFSEEPERQTLIIVFFLSMYLITVFGNLLIIMVTIYDSNLHTPMYFFLSNLSFADICFITMTVPKMLVNIQTQSKVITYAGCITQVYFFLFFSGLDIYLLTVMAYDRFVAICHPLHYMVIMNPRLCGLLLLVTWIISVLHSLLQSLMVLRLSFCTDLEIPHFFCELNQMVQLACCDTFLNNMVMYFAAVLLAGGPLAAILFSYSRIVLSICGISSAQGKSAAFSTCVSHLSVVSLFFCTSLGVYLSSAATHRSHSSAKASVMYAVVTPMLNPFIYSLRNKDIKGALKRLFGMAALQGPVVIGLKNCP", "length": 322, "header": "tr|A0A5G2R0K1-1|A0A5G2R0K1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259901 PE=3 SV=1 CANONICAL=A0A5G2R0K1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R0K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1/entry#A0A5G2R0K1-1", "sequence": { "sequence": "MEPWNLTGVSEFILLGFSEEPERQTLIIVFFLSMYLITVFGNLLIIMVTIYDSNLHTPMYFFLSNLSFADICFITMTVPKMLVNIQTQSKVITYAGCITQVYFFLFFSGLDIYLLTVMAYDRFVAICHPLHYMVIMNPRLCGLLLLVTWIISVLHSLLQSLMVLRLSFCTDLEIPHFFCELNQMVQLACCDTFLNNMVMYFAAVLLAGGPLAAILFSYSRIVLSICGISSAQGKSAAFSTCVSHLSVVSLFFCTSLGVYLSSAATHRSHSSAKASVMYAVVTPMLNPFIYSLRNKDIKGALKRLFGMAALQGPVVIGLKNCP", "length": 322, "header": "tr|A0A5G2R0K1-1|A0A5G2R0K1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259901 PE=3 SV=1 CANONICAL=A0A5G2R0K1-1" }, "locus": { "chromosome": "3", "start_pos": 17055239, "end_pos": 17054274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094403.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094403.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079646.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079646.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0K1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110259901", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259901", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0K1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0K1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0K1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0K1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0K1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 322, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0K1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0K1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0N0-1", "uniprot_ac": "A0A5G2R0N0", "uniprot_id": "A0A5G2R0N0_PIG", "mass": { "chemical_mass": 44628.0, "monoisotopic_mass": 44628.0 }, "refseq": { "ac": "XP_020936630", "name": "heat shock transcription factor, Y-linked-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936630" }, "gene_names": [ { "name": "LOC110257954", "type": "synonym", "evidence": [ { "id": "XP_020936630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936630" } ] } ], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R0N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0N0/entry#names_and_taxonomy" } ] }, { "name": "heat shock transcription factor, Y-linked-like", "type": "synonym", "evidence": [ { "id": "XP_020936630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936630" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0N0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0N0", "locus": {} } ], "crossref": [ { "id": "A0A5G2R0N0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0N0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050201", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050201", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110257954", "url": "https://www.ncbi.nlm.nih.gov/gene/110257954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110257954", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257954", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R0N0", "url": "https://www.orthodb.org/?gene=A0A5G2R0N0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020936630", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936630", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R0N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0N0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLKSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFLPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEECFKKEVLGRKAPFRIFETESMKSLVRQLNLYGFTKLQRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRMKSASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAISTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIAMAQHAIFNQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRRISNFSSGYFGPRVEPSPLPTRYQNISPTEGPVSNPQAAAHPWFPMPMATDTSAALLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2R0N0-1|A0A5G2R0N0_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R0N0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R0N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0N0/entry#A0A5G2R0N0-1", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLKSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFLPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEECFKKEVLGRKAPFRIFETESMKSLVRQLNLYGFTKLQRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRMKSASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAISTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIAMAQHAIFNQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRRISNFSSGYFGPRVEPSPLPTRYQNISPTEGPVSNPQAAAHPWFPMPMATDTSAALLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2R0N0-1|A0A5G2R0N0_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R0N0-1" }, "locus": { "chromosome": "Y", "start_pos": 21303374, "end_pos": 21301746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068046.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068046.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070710.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070710.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 356, "start_aa": "Thr", "end_pos": 356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr356", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "ssc:110257954", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257954", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0N0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0N0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0N0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0N0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0N0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0N0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0N0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0N0" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 356 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2R0S9-1", "uniprot_ac": "A0A5G2R0S9", "uniprot_id": "A0A5G2R0S9_PIG", "mass": { "chemical_mass": 40728.0, "monoisotopic_mass": 40728.0 }, "refseq": {}, "gene_names": [ { "name": "MECR", "type": "recommended", "evidence": [ { "id": "A0A5G2R0S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9" } ] } ], "protein_names": [ { "name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A5G2R0S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9/entry#names_and_taxonomy" } ] }, { "name": "1.3.1.104", "type": "synonym", "evidence": [ { "id": "A0A5G2R0S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9/entry#names_and_taxonomy" } ] }, { "name": "2-enoyl thioester reductase", "type": "synonym", "evidence": [ { "id": "A0A5G2R0S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9/entry#names_and_taxonomy" } ] }, { "name": "Nuclear receptor-binding factor 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R0S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Displays a preference for medium-chain over short- and long-chain substrates. May provide the octanoyl chain used for lipoic acid biosynthesis, regulating protein lipoylation and mitochondrial respiratory activity particularly in Purkinje cells. Involved in iron homeostasis; affecting Fe-S cluster assembly and ceramide metabolism. Required for proper morphology and bioenergetic functions of mitochondria. Required for maintenance of neurons.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9#function" }, { "database": "UniProtKB", "id": "ARBA00053553", "url": "https://www.uniprot.org/uniprotkb/ARBA00053553#function" }, { "database": "UniProtKB", "id": "F1STL4", "url": "https://www.uniprot.org/uniprotkb/F1STL4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MECR", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9", "locus": { "chromosome": "6", "start_pos": 86094423, "end_pos": 86131682, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003589", "url": "https://www.ensembl.org/id/ENSSSCG00000003589" } ] } } ], "crossref": [ { "id": "A0A5G2R0S9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0S9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003589", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003589", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08290", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08290", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515782", "url": "https://www.ncbi.nlm.nih.gov/gene/100515782", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR43981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43981:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43981:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-77346", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77346", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "22564", "url": "https://www.rhea-db.org/rhea/22564", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41812", "url": "https://www.rhea-db.org/rhea/41812", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41832", "url": "https://www.rhea-db.org/rhea/41832", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41848", "url": "https://www.rhea-db.org/rhea/41848", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41864", "url": "https://www.rhea-db.org/rhea/41864", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41880", "url": "https://www.rhea-db.org/rhea/41880", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41896", "url": "https://www.rhea-db.org/rhea/41896", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41912", "url": "https://www.rhea-db.org/rhea/41912", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R0S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STL4", "url": "https://www.uniprot.org/uniprotkb/F1STL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STL4-1", "url": "https://www.uniprot.org/uniprotkb/F1STL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGCGAFWGARAPSQLQRWLLPASRRRRRPAAASFSASAEPSRVQALVYGHHGDPAKVVELKNLELAAVGGSDVHVKMLAAPINPSDINMIQGNYGLLPQLPAVGGNEGVGQVVAVGSHVTGVKPGDWVIPANAGLGTWQTEAVFSEDALIGVPRDIPLQSAATLGVNPCTAYRMLMDFEQLRPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLMDRLKNLGADHVVTEEELRKPEMKNFFKNVPQPRLALNCVGGKSSTELLRHLAPGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFWMSQWKKDHNPDQFKELIFTLCDLIRRGQLSAPACSEVPLQDYQRALEASMQPFVSSKQILTMW", "length": 375, "header": "tr|A0A5G2R0S9-1|A0A5G2R0S9_PIG Isoform 1 of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Sus scrofa OX=9823 GN=MECR PE=1 SV=1 CANONICAL=A0A5G2R0S9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R0S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9/entry#A0A5G2R0S9-1", "sequence": { "sequence": "MWGCGAFWGARAPSQLQRWLLPASRRRRRPAAASFSASAEPSRVQALVYGHHGDPAKVVELKNLELAAVGGSDVHVKMLAAPINPSDINMIQGNYGLLPQLPAVGGNEGVGQVVAVGSHVTGVKPGDWVIPANAGLGTWQTEAVFSEDALIGVPRDIPLQSAATLGVNPCTAYRMLMDFEQLRPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLMDRLKNLGADHVVTEEELRKPEMKNFFKNVPQPRLALNCVGGKSSTELLRHLAPGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFWMSQWKKDHNPDQFKELIFTLCDLIRRGQLSAPACSEVPLQDYQRALEASMQPFVSSKQILTMW", "length": 375, "header": "tr|A0A5G2R0S9-1|A0A5G2R0S9_PIG Isoform 1 of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Sus scrofa OX=9823 GN=MECR PE=1 SV=1 CANONICAL=A0A5G2R0S9-1" }, "locus": { "chromosome": "6", "start_pos": 86131632, "end_pos": 86099852, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090113.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090113.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069980.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069980.1" } ] } }, { "isoform_ac": "F1STL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9/entry#F1STL4-1", "sequence": { "sequence": "MLAAPINPSDINMIQGNYGLLPQLPAVGGNEGVGQVVAVGSHVTGVKPGDWVIPANAGLGTWQTEAVFSEDALIGVPRDIPLQSAATLGVNPCTAYRMLMDFEQLRPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLMDRLKNLGADHVVTEEELRKPEMKNFFKNVPQPRLALNCVGGKSSTELLRHLAPGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFWMSQWKKDHNPDQFKELIFTLCDLIRRGQLSAPACSEVPLQDYQRALEASMQPFVSSKQILTMW", "length": 298, "header": "tr|F1STL4-1|A0A5G2R0S9_PIG Computationally mapped isoform of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Sus scrofa OX=9823 GN=MECR PE=1 SV=4 CANONICAL=A0A5G2R0S9-1" }, "locus": { "chromosome": "6", "start_pos": 86118330, "end_pos": 86099852, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003984.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003984.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003893.4", "url": "https://www.ensembl.org/id/ENSSSCP00000003893.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1STL4", "url": "https://www.uniprot.org/uniprotkb/F1STL4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-77346", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77346", "resource": "Reactome", "description": "Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enoyl-[acyl-carrier-protein] reductase (NADPH) activity", "id": "GO:0141148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141148", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22564", "name": "", "equation": "a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "22564", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22564" } ] }, { "id": "41812", "name": "", "equation": "(2E)-butenoyl-[ACP] + NADPH + H(+) = butanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "41812", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41812" } ] }, { "id": "41832", "name": "", "equation": "(2E)-hexenoyl-[ACP] + NADPH + H(+) = hexanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "41832", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41832" } ] }, { "id": "41848", "name": "", "equation": "(2E)-octenoyl-[ACP] + NADPH + H(+) = octanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "41848", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41848" } ] }, { "id": "41864", "name": "", "equation": "(2E)-decenoyl-[ACP] + NADPH + H(+) = decanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "41864", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41864" } ] }, { "id": "41880", "name": "", "equation": "(2E)-dodecenoyl-[ACP] + NADPH + H(+) = dodecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "41880", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41880" } ] }, { "id": "41896", "name": "", "equation": "(2E)-tetradecenoyl-[ACP] + NADPH + H(+) = tetradecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "41896", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41896" } ] }, { "id": "41912", "name": "", "equation": "(2E)-hexadecenoyl-[ACP] + NADPH + H(+) = hexadecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "41912", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41912" } ] }, { "id": "R-SSC-8952873", "name": "MECR dimer reduces tdec2-CoA to DEC-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-77308" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8952873", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8952873" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-77308", "participant_name": "DEC-CoA [mitochondrial matrix]", "crossref": [ { "id": "C05274", "database": "COMPOUND", "url": "" }, { "id": "61430", "database": "ChEBI", "url": "" }, { "id": "ZINC000096014554", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0S9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 375, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0S9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0S9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S9" }, { "id": "SM00829", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00829" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enoyl reductase (ER)", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 372, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0V0-1", "uniprot_ac": "A0A5G2R0V0", "uniprot_id": "A0A5G2R0V0_PIG", "mass": { "chemical_mass": 44927.0, "monoisotopic_mass": 44927.0 }, "refseq": { "ac": "XP_020936573", "name": "heat shock transcription factor, Y-linked-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936573" }, "gene_names": [ { "name": "LOC110257907", "type": "synonym", "evidence": [ { "id": "XP_020936573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936573" } ] } ], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R0V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V0/entry#names_and_taxonomy" } ] }, { "name": "heat shock transcription factor, Y-linked-like", "type": "synonym", "evidence": [ { "id": "XP_020936573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936573" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V0", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000049276", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000049276", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110257907", "url": "https://www.ncbi.nlm.nih.gov/gene/110257907", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110257907", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257907", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R0V0", "url": "https://www.orthodb.org/?gene=A0A5G2R0V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020936573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R0V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQSEEKAFQALPEGSLMKEPCHTLCASEPDEDSDFLPLPFPRKHWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNGSPVSASLLQGCSKKRSRTGGDVDNHNSDVVAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHVVNFITTTTSISQFRCISNFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNFH", "length": 402, "header": "tr|A0A5G2R0V0-1|A0A5G2R0V0_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R0V0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R0V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V0/entry#A0A5G2R0V0-1", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQSEEKAFQALPEGSLMKEPCHTLCASEPDEDSDFLPLPFPRKHWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNGSPVSASLLQGCSKKRSRTGGDVDNHNSDVVAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHVVNFITTTTSISQFRCISNFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNFH", "length": 402, "header": "tr|A0A5G2R0V0-1|A0A5G2R0V0_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R0V0-1" }, "locus": { "chromosome": "Y", "start_pos": 20117255, "end_pos": 20115627, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104769.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104769.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075708.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075708.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "ssc:110257907", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257907", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V0" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2R0V4-1", "uniprot_ac": "A0A5G2R0V4", "uniprot_id": "A0A5G2R0V4_PIG", "mass": { "chemical_mass": 28241.0, "monoisotopic_mass": 28241.0 }, "refseq": { "ac": "XP_003480825", "name": "syntaxin-10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480825" }, "gene_names": [ { "name": "STX10", "type": "recommended", "evidence": [ { "id": "A0A5G2R0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ] }, { "name": "STX10", "type": "synonym", "evidence": [ { "id": "XP_003480825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480825" } ] } ], "protein_names": [ { "name": "Syntaxin 10", "type": "synonym", "evidence": [ { "id": "A0A5G2R0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4/entry#names_and_taxonomy" } ] }, { "name": "syntaxin-10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003480825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480825" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "STX10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4", "locus": { "chromosome": "2", "start_pos": 65917070, "end_pos": 65914127, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013752", "url": "https://www.ensembl.org/id/ENSSSCG00000013752" } ] } } ], "crossref": [ { "id": "A0A5G2R0V4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0V4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013752", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013752", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15851", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15851", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21446", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21446", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100627609", "url": "https://www.ncbi.nlm.nih.gov/gene/100627609", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100627609", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627609", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERASDCC", "url": "https://omabrowser.org/oma/group/ERASDCC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R0V4", "url": "https://www.orthodb.org/?gene=A0A5G2R0V4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12791", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12791", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003480825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480825", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SD82", "url": "https://www.uniprot.org/uniprotkb/F1SD82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SD82-1", "url": "https://www.uniprot.org/uniprotkb/F1SD82-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQEGAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKAFVERMREAVQEMKDHMVSPAAIAFMEKNNREMLTGKPATLKSSSDLLDASVVSATSRYIEEQQATQQLIMDQQDQQLEMVSGSIRVLKHMSGRVGEELDEQGIMLDAFAHEMDHTQSRMDGVLRKMAKVSHMTSDRRQWCAIVVLLGVLLLVLILFFSL", "length": 249, "header": "tr|A0A5G2R0V4-1|A0A5G2R0V4_PIG Isoform 1 of Syntaxin 10 OS=Sus scrofa OX=9823 GN=STX10 PE=3 SV=2 CANONICAL=A0A5G2R0V4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R0V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4/entry#A0A5G2R0V4-1", "sequence": { "sequence": "MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQEGAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKAFVERMREAVQEMKDHMVSPAAIAFMEKNNREMLTGKPATLKSSSDLLDASVVSATSRYIEEQQATQQLIMDQQDQQLEMVSGSIRVLKHMSGRVGEELDEQGIMLDAFAHEMDHTQSRMDGVLRKMAKVSHMTSDRRQWCAIVVLLGVLLLVLILFFSL", "length": 249, "header": "tr|A0A5G2R0V4-1|A0A5G2R0V4_PIG Isoform 1 of Syntaxin 10 OS=Sus scrofa OX=9823 GN=STX10 PE=3 SV=2 CANONICAL=A0A5G2R0V4-1" }, "locus": { "chromosome": "2", "start_pos": 65916768, "end_pos": 65914276, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067973.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067973.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070743.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070743.2" } ] } }, { "isoform_ac": "F1SD82-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4/entry#F1SD82-1", "sequence": { "sequence": "MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQEGAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKAFVERMREAVQEMKDHMVSPAAIAFMEKNNREMLTGKPATLKSSSDLLDASVVSATSRYIEEQQATQQLIMDQQDQQLEMVSGSIRVLKHMSGRVGEELDEQGIMLDAFAHEMDHTQSRMDGVLRKMAKVSHMTSGESPGRSDLAVGGGEWVVGRTASPL", "length": 249, "header": "tr|F1SD82-1|F1SD82_PIG Computationally mapped isoform of Syntaxin 10 OS=Sus scrofa OX=9823 GN=STX10 PE=3 SV=4 CANONICAL=A0A5G2R0V4-1" }, "locus": { "chromosome": "2", "start_pos": 65916669, "end_pos": 65914276, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015026.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015026.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014621.5", "url": "https://www.ensembl.org/id/ENSSSCP00000014621.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100627609", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627609", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32U3L2-1", "protein_name": "Syntaxin-10 isoform X1", "gene_name": "stx10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSMEDPFFVVKGEVQKALSKAQGLYERWEELLQEETPVSRDELDWSTNELRNCLRAIDWDLEDLHETISIVEANPGKFRLGEHELQERRDFVERTRKSVQLMKEQLSSPSAVAQAEKKNKQALLGATAKDRYAGLEPHLVSANSRYIQEQQEQQQLIMQDQDEHLELVTGSIRVLKDMSSRIGDELDEQAVMLGEFNEEMDQTGSRMDSVLKKMEKVSHMTSKQHGGAMGSTIASQQEGCWFEPRLG", "length": 247 }, "evidence": [ { "id": "A0A5G2R0V4", "url": "https://omabrowser.org/oma/group/A0A5G2R0V4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O60499-1", "protein_name": "Syntaxin-10", "gene_name": "STX10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQWCAIAVLVGVLLLVLILLFSL", "length": 249 }, "evidence": [ { "id": "A0A5G2R0V4", "url": "https://omabrowser.org/oma/group/A0A5G2R0V4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03322-1", "protein_name": "t-SNARE affecting a late Golgi compartment protein 1", "gene_name": "TLG1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNNSEDPFQQVVKDTKEQLNRINNYITRHNTAGDDDQEEEIQDILKDVEETIVDLDRSIIVMKRDENEDVSGREAQVKNIKQQLDALKLRFDRRIQESTQTTIPLEETVENSTLNTSMAENNDGGMSNPFQEQMLREQDVHLDGIHKTMQNLHIQAQTMGDELENQGQLLDNMDEGMDGVVNKLARGRRQLEWVYEKNKEKYDDCCIGLLIVVLIVLLVLAFIA", "length": 224 }, "evidence": [ { "id": "A0A5G2R0V4", "url": "https://omabrowser.org/oma/group/A0A5G2R0V4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54PQ5-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "syn10", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MASPDQDPYYLAEQDIASSVRGIMTTHEKWKQLLFNTNTYTNKEFKWYNKEIRKVLAVIEEDIGDILEAIGTIEKFPGRYVLAPGELDRRKLFANDVKIKINEIKEDLQSPRALAKIEEDKQNELLSSEKRNMIERGGKFEGLRRAHDEDNRDFLREQAGYQRELMNRQDEGLDQMKDDVQILGEMGKAMHSELKIQEGLLDSLHDRAARSSETLGSVMRKLDRFMESTSSKLQWTIIAILGIIFVGLVVLTTMIKK", "length": 257 }, "evidence": [ { "id": "A0A5G2R0V4", "url": "https://omabrowser.org/oma/group/A0A5G2R0V4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "pmid": "" }, { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "pmid": "" }, { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0V4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 249, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0V4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0V4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V4" }, { "id": "PS50192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-SNARE coiled-coil homology", "eco_id": "ECO_0000259", "start_pos": 157, "end_pos": 219, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0X9-1", "uniprot_ac": "A0A5G2R0X9", "uniprot_id": "A0A5G2R0X9_PIG", "mass": { "chemical_mass": 35753.0, "monoisotopic_mass": 35753.0 }, "refseq": { "ac": "XP_003128649", "name": "olfactory receptor 4F15-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128649" }, "gene_names": [ { "name": "LOC100514909", "type": "recommended", "evidence": [ { "id": "A0A5G2R0X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9" } ] }, { "name": "LOC100514909", "type": "synonym", "evidence": [ { "id": "XP_003128649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128649" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R0X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4F15-like", "type": "synonym", "evidence": [ { "id": "XP_003128649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128649" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0X9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0X9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100514909", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9", "locus": {} } ], "crossref": [ { "id": "A0A5G2R0X9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0X9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100514909", "url": "https://www.ncbi.nlm.nih.gov/gene/100514909", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514909", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514909", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R0X9", "url": "https://www.orthodb.org/?gene=A0A5G2R0X9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003128649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128649", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R0X9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVRNHSIVSEFVFLRFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFRDLNVLDSFYCDLSRLLKLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312, "header": "tr|A0A5G2R0X9-1|A0A5G2R0X9_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100514909 PE=3 SV=1 CANONICAL=A0A5G2R0X9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R0X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9/entry#A0A5G2R0X9-1", "sequence": { "sequence": "MDVRNHSIVSEFVFLRFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFRDLNVLDSFYCDLSRLLKLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312, "header": "tr|A0A5G2R0X9-1|A0A5G2R0X9_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100514909 PE=3 SV=1 CANONICAL=A0A5G2R0X9-1" }, "locus": { "chromosome": "AEMK02000131.1", "start_pos": 58154, "end_pos": 57219, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091307.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091307.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070030.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070030.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0X9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514909", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514909", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0X9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0X9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0X9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0X9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0X9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0X9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 310, "end_pos": 312 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R0Z8-1", "uniprot_ac": "A0A5G2R0Z8", "uniprot_id": "A0A5G2R0Z8_PIG", "mass": { "chemical_mass": 45310.0, "monoisotopic_mass": 45310.0 }, "refseq": {}, "gene_names": [ { "name": "HSDL2", "type": "recommended", "evidence": [ { "id": "A0A5G2R0Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8" } ] } ], "protein_names": [ { "name": "Hydroxysteroid dehydrogenase-like protein 2", "type": "recommended", "evidence": [ { "id": "A0A5G2R0Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Has apparently no steroid dehydrogenase activity. Controls bile acid (BA) and lipid metabolism in response to nutritional cues.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0Z8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8#function" }, { "database": "UniProtKB", "id": "ARBA00045401", "url": "https://www.uniprot.org/uniprotkb/ARBA00045401#function" }, { "database": "UniProtKB", "id": "A0A5G2R8L9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8L9#function" }, { "database": "UniProtKB", "id": "F1SNA8", "url": "https://www.uniprot.org/uniprotkb/F1SNA8#function" }, { "database": "UniProtKB", "id": "K7GNL4", "url": "https://www.uniprot.org/uniprotkb/K7GNL4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0Z8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HSDL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8", "locus": { "chromosome": "1", "start_pos": 253194951, "end_pos": 253124471, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005467", "url": "https://www.ensembl.org/id/ENSSSCG00000005467" } ] } } ], "crossref": [ { "id": "A0A5G2R0Z8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0Z8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005467", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005467", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09762", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09762", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WWSSVAN", "url": "https://omabrowser.org/oma/group/WWSSVAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR42808", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42808", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42808:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42808:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R0Z8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8L9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SNA8", "url": "https://www.uniprot.org/uniprotkb/F1SNA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SNA8-1", "url": "https://www.uniprot.org/uniprotkb/F1SNA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GNL4", "url": "https://www.uniprot.org/uniprotkb/K7GNL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GNL4-1", "url": "https://www.uniprot.org/uniprotkb/K7GNL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPNTGRLAGCTVFITGASRGIGKAIALKAAKDGANVVIAAKTTQTHPKLQGTIYTAAEEIQAAGGKALPCVVDVRDEQQISDAVEKAVEKFGGIDILVNNASAISLTNTLETPTKRVDLMMNVNTRGTYLTSKACIPYLKKSRIAHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFKGEIAVNALWPKTAIHTAAMDMLGGSGIESQCRKVDIIADAAYCIFKKPKSFTGNFIIDENILKEEGITNFDVYAVTPGHPLLPDFFLDEQPETVIKKMESHGADPELKKEKLPPPPKPCSGAVEETFRIVKESLSDDVVKATQAIYQFELSGEDGGTWFLDLKSKGGNVGYGEPSDRADVVMSMSTDDFVKMFSGKLKPVVAFLSGKLKIKGNMALAIKLEKLMNQMNARL", "length": 418, "header": "tr|A0A5G2R0Z8-1|A0A5G2R0Z8_PIG Isoform 1 of Hydroxysteroid dehydrogenase-like protein 2 OS=Sus scrofa OX=9823 GN=HSDL2 PE=1 SV=1 CANONICAL=A0A5G2R0Z8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R0Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8/entry#A0A5G2R0Z8-1", "sequence": { "sequence": "MLPNTGRLAGCTVFITGASRGIGKAIALKAAKDGANVVIAAKTTQTHPKLQGTIYTAAEEIQAAGGKALPCVVDVRDEQQISDAVEKAVEKFGGIDILVNNASAISLTNTLETPTKRVDLMMNVNTRGTYLTSKACIPYLKKSRIAHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFKGEIAVNALWPKTAIHTAAMDMLGGSGIESQCRKVDIIADAAYCIFKKPKSFTGNFIIDENILKEEGITNFDVYAVTPGHPLLPDFFLDEQPETVIKKMESHGADPELKKEKLPPPPKPCSGAVEETFRIVKESLSDDVVKATQAIYQFELSGEDGGTWFLDLKSKGGNVGYGEPSDRADVVMSMSTDDFVKMFSGKLKPVVAFLSGKLKIKGNMALAIKLEKLMNQMNARL", "length": 418, "header": "tr|A0A5G2R0Z8-1|A0A5G2R0Z8_PIG Isoform 1 of Hydroxysteroid dehydrogenase-like protein 2 OS=Sus scrofa OX=9823 GN=HSDL2 PE=1 SV=1 CANONICAL=A0A5G2R0Z8-1" }, "locus": { "chromosome": "1", "start_pos": 253190855, "end_pos": 253124544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091367.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091367.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070840.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070840.1" } ] } }, { "isoform_ac": "A0A5G2R8L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8/entry#A0A5G2R8L9-1", "sequence": { "sequence": "MLPNTGRLAGCTVFITGASRGIGKAIALKAAKDGANVVIAAKTTQTHPKLQGTIYTAAEEIQAAGGKALPCVVDVRDEQQISDAVEKAVEKFGAYTIAKYGMSMCVLGMAEEFKGEIAVNALWPKTAIHTAAMDMLGGSGIESQCRKVDIIADAAYCIFKKPKSFTGNFIIDENILKEEGITNFDVYAVTPGHPLLPDFFLDEQPETVIKKMESHGADPELKKEKLPPPPKPCSGAVEETFRIVKESLSDDVVKATQAIYQFELSGEDGGTWFLDLKSKGGNVGYGEPSDRADVVMSMSTDDFVKMFSGKLKPVVAFLSGKLKIKGNMALAIKLEKLMNQMNARL", "length": 345, "header": "tr|A0A5G2R8L9-1|A0A5G2R0Z8_PIG Computationally mapped isoform of Hydroxysteroid dehydrogenase-like protein 2 OS=Sus scrofa OX=9823 GN=HSDL2 PE=1 SV=1 CANONICAL=A0A5G2R0Z8-1" }, "locus": { "chromosome": "1", "start_pos": 253190855, "end_pos": 253124544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074952.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074952.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073431.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073431.1" } ] } }, { "isoform_ac": "F1SNA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8/entry#F1SNA8-1", "sequence": { "sequence": "MLPNTGRLAGCTVFITGASRGIGKAIALKAAKDGANVVIAAKTTQTHPKLQGTIYTAAEEIQAAGGKALPCVVDVRDEQQISDAVEKAVEKFGGIDILVNNASAISLTNTLETPTKRVDLMMNVNTRGTYLTSKACIPYLKKSRIAHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFKGEIAVNALWPKTAIHTAAMDMLGGSGIESQCRKVDIIADAAYCIFKKPKSFTGNFIIDENILKEEGITNFDVYAVTPGHPLLPDFFLDEQPETVIKKMESHGADPELKKEKLPPPPKPCSGAVEETFRIVKESLSDDVVKATQAIYQFELSGKLKPVVAFLSGKLKIKGNMALAIKLEKLMNQMNARL", "length": 375, "header": "tr|F1SNA8-1|A0A5G2R0Z8_PIG Computationally mapped isoform of Hydroxysteroid dehydrogenase-like protein 2 OS=Sus scrofa OX=9823 GN=HSDL2 PE=1 SV=2 CANONICAL=A0A5G2R0Z8-1" }, "locus": { "chromosome": "1", "start_pos": 253190855, "end_pos": 253124544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006013.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006013.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005864.3", "url": "https://www.ensembl.org/id/ENSSSCP00000005864.3" } ] } }, { "isoform_ac": "K7GNL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8/entry#K7GNL4-1", "sequence": { "sequence": "MQQWDFVGSQRLAGCTVFITGASRGIGKAIALKAAKDGANVVIAAKTTQTHPKLQGTIYTAAEEIQAAGGKALPCVVDVRDEQQISDAVEKAVEKFGGIDILVNNASAISLTNTLETPTKRVDLMMNVNTRGTYLTSKACIPYLKKSRIAHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFKGEIAVNALWPKTAIHTAAMDMLGGSGIESQCRKVDIIADAAYCIFKKPKSFTGNFIIDENILKEEGITNFDVYAVTPGHPLLPDFFLDEQPETVIKKMESHGADPELKKEKLPPPPKPCSGAVEETFRIVKESLSDDVVKATQAIYQFELSGKLKPVVAFLSGKLKIKGNMALAIKLEKLMNQMNARL", "length": 379, "header": "tr|K7GNL4-1|A0A5G2R0Z8_PIG Computationally mapped isoform of Hydroxysteroid dehydrogenase-like protein 2 OS=Sus scrofa OX=9823 GN=HSDL2 PE=1 SV=3 CANONICAL=A0A5G2R0Z8-1" }, "locus": { "chromosome": "1", "start_pos": 253190855, "end_pos": 253131688, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000034705.4", "url": "https://www.ensembl.org/id/ENSSSCT00000034705.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029469.3", "url": "https://www.ensembl.org/id/ENSSSCP00000029469.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 263, "start_aa": "Thr", "end_pos": 263, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr263", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SNA8", "url": "https://www.uniprot.org/uniprotkb/F1SNA8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A4FUZ6-1", "protein_name": "Hydroxysteroid dehydrogenase-like protein 2", "gene_name": "HSDL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPNTGKLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQAHPKLPGTIYTAAEEIKAAGGKALPCIVDVRDEEQISSAVEKAVEKFGGIDILVNNASAISLTNTLETPTKKVDLMMNVNTRGTYLTSKACIPYLKKSKVAHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFKGEIAVNALWPRTAIHTAAMDMLGGSGVESQCRKVDIMADAAYCIFKKPKSFTGNFIIDENILKEEGIKNFDVYAITPGHPLLPDFFLDEQPAMVTKKADSYGAVPELKEEKTQPPPKARSGAVEETFRIVKDSLSDDIVKATQAVYQFELSGEDGGTWFLDLKSKGGNIGYGEPSDQADVVMSMSTDDFVKMFSGKLKPTMAFMSGKLKIKGNMALAIKLEKLMNQMNSKL", "length": 418 }, "evidence": [ { "id": "A0A5G2R0Z8", "url": "https://omabrowser.org/oma/group/A0A5G2R0Z8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1C7S2-1", "protein_name": "Hydroxysteroid dehydrogenase-like protein 2", "gene_name": "HSDL2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPNTGKLAGCTLFITGASRGIGKAIALKAARDGANIVIAAKTAEPHPKLPGTIYTAAEEIEAAGGRALPCIVNVRQEEQIISAVEKAVKTFGGIDILVNNASAISLTGTLETETKKVNLMMDVNVRGTYLTSKACLPYLRKSKNPHILNLSPPMNMKPIWFKNHCAYTISKYGMSMCVLGMAEEFKGEVAVNALWPKTAIHTAAMDMLGGSGIEKQCRKTDIIADAAYCILTKPKSFTGNFIIDEVLLREEGVKDFDVYAIAPGHPLMPDFFLDAETDMTESHGASQASDGAKANKESAPAGPVAETFRLIQGELNKEMVKSTQGVFQFELSGDEGGTWYLDLKTSSGSAGFGKPPAAADVVMSMSSGDFVKMFTGKLKPTMAFMSGKLRIKGNMALAVKLEKMLTQFNAKL", "length": 413 }, "evidence": [ { "id": "A0A5G2R0Z8", "url": "https://omabrowser.org/oma/group/A0A5G2R0Z8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q2TPA8-1", "protein_name": "Hydroxysteroid dehydrogenase-like protein 2", "gene_name": "Hsdl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPNTGKLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTTQKHPKLLGTIYTAAEEIEAAGGTALPCVVDVRDEQQINSAVEKAVEKFGGIDILVNNASAISLTNTLDTPTKRVDLMMNVNTRGTYLTSKACIPFLKKSKVGHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFRGEIAVNALWPRTAIHTAAMDMLGGSGVENQCRKVDIIADAAYSIFKRPKSFTGNFIIDENILKEEGIKNFDVYAIAPGHPLLPDFFLDEHPDAVMEEKESNDSVPEVKEEKLQLQEESQLQKQPQLQEQPQLQEKPQLQEKPQLQEQPQLQEKPQLQEQPQQREQPQLQQQPRPRQQPQPFVQSMLPQKPHFGAVEETFRIVKDSLSDEVVRATQAVYQFELSGEDGGTWFLDLKSKGGKVGHGEPSDRADVVMSMATDDFVKMFSGKLKPTMAFMSGKLKIKGNIALAIKLEKLMTQMNSRL", "length": 490 }, "evidence": [ { "id": "A0A5G2R0Z8", "url": "https://omabrowser.org/oma/group/A0A5G2R0Z8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4V8F9-1", "protein_name": "Hydroxysteroid dehydrogenase-like protein 2", "gene_name": "Hsdl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPNTGKLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTTQRHPKLLGTIYTAAEEIEAAGGKALPCVVDVRDEQQINSAVEKAVERFGGIDILVNNASAISLTNTLETPTKRVDLMMSVNTRGTYLTSKACIPFLKKSKVAHILNLSPPLNLNPMWFKQHCAYTIAKYGMSMCVLGMAEEFRGEIAVNALWPRTAIHTAAMDMLGGAGVESQCRKVDIIADAAYSIFKRPKSFTGNFIIDENILKEEGIKDFDIYAITPGHPLLPDFFLDEHPDAVMEEKESYDPVPEVKEEKLQLQEQPQLQEQPQLQEKPQLQEQPQLQEKPQLQEQPQLQEQPQLQEQPQQQPQLQEQPQLQEKPQLQEQPQQQEKPQPQQQPQQQPQQRPQQRPQPQPQPQPLLQSVLPPKPHFGAVEETFRIVKDSLSDEVVRATQAVYQFELSGEDGGTWFLDLKSKGGKVGHGEPSDRADVVMSMATEDFVKMFSGKLKPTMAFMSGKLKIKGNIALAIKLEKLMTHMNSRL", "length": 524 }, "evidence": [ { "id": "A0A5G2R0Z8", "url": "https://omabrowser.org/oma/group/A0A5G2R0Z8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54DN0-1", "protein_name": "Hydroxysteroid dehydrogenase-like protein 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLKGKTIFITGASRGIGEAIAIAAGKEGANVVIAAKTADPHPKLKGTIFSVQKAVEDAGGKCLACSVDIRFEDQIEDAVKKAVEKFGGIDILINNASAISLTGTLETNSKKFDLMMGVNTRGTYLTTQKCLPYLLKSKTAHVINLSPPLNMDKKWFANHPAYTMAKYGMSMCVLGMAEEFKGKVAFNALWPKTAIYTAAMEMLGGSDVGKQCRTVDILSDSVMWILKQPITTTGNFFIDEYCVKQAGITDLEKYSIVKGAKLMNDFFLEDDVDYSILPTPKL", "length": 282 }, "evidence": [ { "id": "A0A5G2R0Z8", "url": "https://omabrowser.org/oma/group/A0A5G2R0Z8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6P5L8-1", "protein_name": "Hydroxysteroid dehydrogenase-like protein 2", "gene_name": "hsdl2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLQNTGKLAGCTIFITGASRGIGKAIALKAAQDGANVVIAAKTADPHPKLPGTIYTAAAEIEAAGGKALPCIVDVRDEKQINDAVEQAVEKFGGIDILVNNASAINLTGTLQTPMKKADLMLGINLRGTYLTSKLCIPHLLKSKNPHILNLSPPLNLNPIWFKNHTAYTIAKYGMSMCVLGMAEEFRGSIAVNALWPKTAIQTAAMDMLGGSEVGKQCRKVEIMADAAYAIFKQPTSFTGQFVIDEDILKKEGIKDFDVYAVEPGHPLLPDFFLDGQPEDLVKHMEAHGATPAFTTAKADPVAAGPVSEMFNTIRGIISPEMVKTTQGVYKFNLAGEHAGVWYLDLKNDAGSAGNGEPPVKADVVMSMDSEDFVKMFGGKLKPTMAFMSGKLTIKGDMGLAIKLEKMMAMMKSKL", "length": 415 }, "evidence": [ { "id": "A0A5G2R0Z8", "url": "https://omabrowser.org/oma/group/A0A5G2R0Z8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6YN16-1", "protein_name": "Hydroxysteroid dehydrogenase-like protein 2", "gene_name": "HSDL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPNTGRLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRGTYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEEFKGEIAVNALWPKTAIHTAAMDMLGGPGIESQCRKVDIIADAAYSIFQKPKSFTGNFVIDENILKEEGIENFDVYAIKPGHPLQPDFFLDEYPEAVSKKVESTGAVPEFKEEKLQLQPKPRSGAVEETFRIVKDSLSDDVVKATQAIYLFELSGEDGGTWFLDLKSKGGNVGYGEPSDQADVVMSMTTDDFVKMFSGKLKPTMAFMSGKLKIKGNMALAIKLEKLMNQMNARL", "length": 418 }, "evidence": [ { "id": "A0A5G2R0Z8", "url": "https://omabrowser.org/oma/group/A0A5G2R0Z8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VB10-1", "protein_name": "Hydroxysteroid dehydrogenase-like protein 2", "gene_name": "Hsdl2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MINTGKLAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAGGKAYPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAISLTNTPDTDMKRYDLMHNINTRGTFLVSKVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVNALWPRTAIHTAAIEMLTGPDSAKWSRKPEIMADAAYAILTREPRQSTGQFFVDDEVLESAGITDLTEYACFRENADKLMVDFFVEEKGAPVENEAAAEDAAAPASGGDVKIPQLFRKIESLLSPEIVSKTQAVFQFNISGAEQGTWFLDLKNGSGSCGAGTPTAAPDATLTMNSKNFFDMFSGKLKAAPAYMTGKLKISGDFQKALKLEKLMKALKSKL", "length": 412 }, "evidence": [ { "id": "A0A5G2R0Z8", "url": "https://omabrowser.org/oma/group/A0A5G2R0Z8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0Z8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0Z8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0Z8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0Z8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R0Z8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 418, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R0Z8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R0Z8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R0Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0Z8" }, { "id": "PF02036", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02036" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCP2", "eco_id": "ECO_0000259", "start_pos": 319, "end_pos": 411, "start_aa": "Glu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 263 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 150, "end_pos": 152 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R151-1", "uniprot_ac": "A0A5G2R151", "uniprot_id": "A0A5G2R151_PIG", "mass": { "chemical_mass": 35507.0, "monoisotopic_mass": 35507.0 }, "refseq": { "ac": "XP_003354454", "name": "olfactory receptor 2T11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354454" }, "gene_names": [ { "name": "LOC100624524", "type": "recommended", "evidence": [ { "id": "A0A5G2R151", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151" } ] }, { "name": "LOC100624524", "type": "synonym", "evidence": [ { "id": "XP_003354454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354454" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R151", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2T11", "type": "synonym", "evidence": [ { "id": "XP_003354454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354454" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R151", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R151", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100624524", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151", "locus": {} } ], "crossref": [ { "id": "A0A5G2R151", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R151", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100624524", "url": "https://www.ncbi.nlm.nih.gov/gene/100624524", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624524", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624524", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IQIFLYM", "url": "https://omabrowser.org/oma/group/IQIFLYM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R151", "url": "https://www.orthodb.org/?gene=A0A5G2R151", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003354454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354454", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R151", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R151-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENRNSTSDFILLGLLVNNKATGVVFAGIFTIFAVAVTANLVMIFLIKVDSRLHTPMYFLLSQLSIMDTLFICTTVPKLLVDMVSKEKTISFVACGIQIFLYLTMIGSEFFLLGLMAYDRYVAVCNPLRYPVLMNRRVCLLLAAGAWFGGSLDGFLLTPVTMTFPYCGSRSINHFFCEIPAVLRLACADTSLYETLMYSCCVLMLLIPISIISTSYTLILLTVHRMRSVEGRRKAFTTCSSHLTVVSIFYGAAFYNYVLPQSFHTPEQDKVVSAFYTMVTPMLNPLIYSLRNKDVMGAFKKIFAQCLSIQNVSTIYA", "length": 317, "header": "tr|A0A5G2R151-1|A0A5G2R151_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100624524 PE=3 SV=1 CANONICAL=A0A5G2R151-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R151-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151/entry#A0A5G2R151-1", "sequence": { "sequence": "MENRNSTSDFILLGLLVNNKATGVVFAGIFTIFAVAVTANLVMIFLIKVDSRLHTPMYFLLSQLSIMDTLFICTTVPKLLVDMVSKEKTISFVACGIQIFLYLTMIGSEFFLLGLMAYDRYVAVCNPLRYPVLMNRRVCLLLAAGAWFGGSLDGFLLTPVTMTFPYCGSRSINHFFCEIPAVLRLACADTSLYETLMYSCCVLMLLIPISIISTSYTLILLTVHRMRSVEGRRKAFTTCSSHLTVVSIFYGAAFYNYVLPQSFHTPEQDKVVSAFYTMVTPMLNPLIYSLRNKDVMGAFKKIFAQCLSIQNVSTIYA", "length": 317, "header": "tr|A0A5G2R151-1|A0A5G2R151_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100624524 PE=3 SV=1 CANONICAL=A0A5G2R151-1" }, "locus": { "chromosome": "2", "start_pos": 52988163, "end_pos": 52987213, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086801.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086801.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070895.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070895.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R151", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624524", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624524", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R151", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R151", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R151", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R151", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R151-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 317, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R151-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R151" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R151", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R151" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 311, "end_pos": 313 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R178-1", "uniprot_ac": "A0A5G2R178", "uniprot_id": "A0A5G2R178_PIG", "mass": { "chemical_mass": 34063.0, "monoisotopic_mass": 34063.0 }, "refseq": { "ac": "XP_013847483", "name": "olfactory receptor 2L3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847483" }, "gene_names": [ { "name": "LOC106508617", "type": "recommended", "evidence": [ { "id": "A0A5G2R178", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178" } ] }, { "name": "LOC106508617", "type": "synonym", "evidence": [ { "id": "XP_013847483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847483" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R178", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2L3", "type": "synonym", "evidence": [ { "id": "XP_013847483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847483" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R178", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R178", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC106508617", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178", "locus": {} } ], "crossref": [ { "id": "A0A5G2R178", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R178", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "106508617", "url": "https://www.ncbi.nlm.nih.gov/gene/106508617", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:106508617", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106508617", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R178", "url": "https://www.orthodb.org/?gene=A0A5G2R178", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013847483", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847483", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R178", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R178-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENYTQTSTDFILLGLFPPSKIGMFLFILIVLIFLMALFGNLSMILLIYLDTQLHTPMYFLLSQLSFIDLNYISTIVPKMVSNFLSGNKSISFIGCGVQSFFFLILAVAEALLLTSMAYDRYVAICFPLHYPIRISRRVCVLMIIGSWIISSINSCAHTAYALHIPYCRSRAINHFFCDVPAMLTLACMDTWVYEYTVFVSTTLFLVLPFIIIACSYGRVLLAVFHMNSAEGKRKAYSTCSTHLTVVTFYYAPFFYTYLRPRSHRSPTGDKALAVFYTILTPMLNPVIYSLRNKEVMEA", "length": 299, "header": "tr|A0A5G2R178-1|A0A5G2R178_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC106508617 PE=3 SV=1 CANONICAL=A0A5G2R178-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R178-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178/entry#A0A5G2R178-1", "sequence": { "sequence": "MENYTQTSTDFILLGLFPPSKIGMFLFILIVLIFLMALFGNLSMILLIYLDTQLHTPMYFLLSQLSFIDLNYISTIVPKMVSNFLSGNKSISFIGCGVQSFFFLILAVAEALLLTSMAYDRYVAICFPLHYPIRISRRVCVLMIIGSWIISSINSCAHTAYALHIPYCRSRAINHFFCDVPAMLTLACMDTWVYEYTVFVSTTLFLVLPFIIIACSYGRVLLAVFHMNSAEGKRKAYSTCSTHLTVVTFYYAPFFYTYLRPRSHRSPTGDKALAVFYTILTPMLNPVIYSLRNKEVMEA", "length": 299, "header": "tr|A0A5G2R178-1|A0A5G2R178_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC106508617 PE=3 SV=1 CANONICAL=A0A5G2R178-1" }, "locus": { "chromosome": "2", "start_pos": 53613386, "end_pos": 53612490, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037483.2", "url": "https://www.ensembl.org/id/ENSSSCT00000037483.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070115.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070115.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R178", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:106508617", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106508617", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R178", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R178", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R178", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R178", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R178-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 299, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R178-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R178" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R178", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R178" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R190-1", "uniprot_ac": "A0A5G2R190", "uniprot_id": "A0A5G2R190_PIG", "mass": { "chemical_mass": 35628.0, "monoisotopic_mass": 35628.0 }, "refseq": { "ac": "XP_003481773", "name": "olfactory receptor 8S1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481773" }, "gene_names": [ { "name": "LOC100737025", "type": "recommended", "evidence": [ { "id": "A0A5G2R190", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190" } ] }, { "name": "LOC100737025", "type": "synonym", "evidence": [ { "id": "XP_003481773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481773" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R190", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8S1-like", "type": "synonym", "evidence": [ { "id": "XP_003481773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481773" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R190", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R190", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100737025", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190", "locus": {} } ], "crossref": [ { "id": "A0A5G2R190", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R190", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15229", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15229", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737025", "url": "https://www.ncbi.nlm.nih.gov/gene/100737025", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737025", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737025", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IACTESF", "url": "https://omabrowser.org/oma/group/IACTESF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R190", "url": "https://www.orthodb.org/?gene=A0A5G2R190", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003481773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481773", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R190", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R190-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLGNHSTIPEFILLGLSADPHIQVTFFVLFLWIYLLTMMGNLMMMLVIRMDSHLHSPMYFFLSHLSFLDLCLTSVIVPKMLENLLSRTKSIPIEGCLAQAFFVFSIAGTEVFVLSAMAYDRYTAICHPLVYGQLMSKQLCRGLVWGSWGLSFLDALINTLMTLNLDFCGAHVMPHFSCELPSLLSLSCSDISINFSVLGCSAVMHAFGTLLLVFFSYARIVSTILNISSTTGRSKAFSTCSSHLTAVSFFYGSAFLRYFMPNLSSPLELIFSIQYSVVTPLVNPLVYSLKNKEVKEALRRMLRKGLQHRRWRTSGE", "length": 317, "header": "tr|A0A5G2R190-1|A0A5G2R190_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100737025 PE=3 SV=1 CANONICAL=A0A5G2R190-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R190-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190/entry#A0A5G2R190-1", "sequence": { "sequence": "MVLGNHSTIPEFILLGLSADPHIQVTFFVLFLWIYLLTMMGNLMMMLVIRMDSHLHSPMYFFLSHLSFLDLCLTSVIVPKMLENLLSRTKSIPIEGCLAQAFFVFSIAGTEVFVLSAMAYDRYTAICHPLVYGQLMSKQLCRGLVWGSWGLSFLDALINTLMTLNLDFCGAHVMPHFSCELPSLLSLSCSDISINFSVLGCSAVMHAFGTLLLVFFSYARIVSTILNISSTTGRSKAFSTCSSHLTAVSFFYGSAFLRYFMPNLSSPLELIFSIQYSVVTPLVNPLVYSLKNKEVKEALRRMLRKGLQHRRWRTSGE", "length": 317, "header": "tr|A0A5G2R190-1|A0A5G2R190_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100737025 PE=3 SV=1 CANONICAL=A0A5G2R190-1" }, "locus": { "chromosome": "5", "start_pos": 79026672, "end_pos": 79025722, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073210.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073210.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067976.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067976.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R190", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737025", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737025", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R190", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R190", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R190", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R190", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R190-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 317, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R190-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R190" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R190", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R190" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1D1-1", "uniprot_ac": "A0A5G2R1D1", "uniprot_id": "A0A5G2R1D1_PIG", "mass": { "chemical_mass": 35494.0, "monoisotopic_mass": 35494.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110259614", "type": "recommended", "evidence": [ { "id": "A0A5G2R1D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R1D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259614", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1", "locus": {} } ], "crossref": [ { "id": "A0A5G2R1D1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1D1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R1D1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALMGNKTFISHFILLGLFTHSPLHLLLFSIIMVMFLVALSGNGLMILLINIDSRLHIPMYFFLSWLSLMDLMLISTIVPRMAIDFLLGSGSISFTGCGLQILFFVTLLGDECFLLAFMAYDRYVAISNPLRYSVVMSRRVCWLMVAWSWLFGLVDGLIQAVFTLRFPYCGSQEIDHFFCEVPAVLKLACADTSLYETMIYVCCVLMLLLPFSVISASYLRILLTVLHMRSAEGREKAFATCSSHMAVVSLFYGAAMITYMRPQAYHSSRQDKVVSAFYTMITPMLNPLIYSLRNKEVAGAFRKLLGKYTCCAR", "length": 314, "header": "tr|A0A5G2R1D1-1|A0A5G2R1D1_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110259614 PE=3 SV=2 CANONICAL=A0A5G2R1D1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1/entry#A0A5G2R1D1-1", "sequence": { "sequence": "MALMGNKTFISHFILLGLFTHSPLHLLLFSIIMVMFLVALSGNGLMILLINIDSRLHIPMYFFLSWLSLMDLMLISTIVPRMAIDFLLGSGSISFTGCGLQILFFVTLLGDECFLLAFMAYDRYVAISNPLRYSVVMSRRVCWLMVAWSWLFGLVDGLIQAVFTLRFPYCGSQEIDHFFCEVPAVLKLACADTSLYETMIYVCCVLMLLLPFSVISASYLRILLTVLHMRSAEGREKAFATCSSHMAVVSLFYGAAMITYMRPQAYHSSRQDKVVSAFYTMITPMLNPLIYSLRNKEVAGAFRKLLGKYTCCAR", "length": 314, "header": "tr|A0A5G2R1D1-1|A0A5G2R1D1_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110259614 PE=3 SV=2 CANONICAL=A0A5G2R1D1-1" }, "locus": { "chromosome": "2", "start_pos": 57617002, "end_pos": 57568253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088709.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088709.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064327.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064327.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1D1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1D1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1D1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1D2-1", "uniprot_ac": "A0A5G2R1D2", "uniprot_id": "A0A5G2R1D2_PIG", "mass": { "chemical_mass": 37487.0, "monoisotopic_mass": 37487.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Vomeronasal type-1 receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative pheromone receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2#function" }, { "database": "UniProtKB", "id": "ARBA00003878", "url": "https://www.uniprot.org/uniprotkb/ARBA00003878#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2", "locus": {} } ], "crossref": [ { "id": "A0A5G2R1D2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1D2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24062", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24062", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R1D2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GKAPRDMGTFHILCWTLNMILNILTRSSSPGCDRMDTKDWAIGMIFLLQTTAGLLGNCSLLYHFLFLYLTGGTSRSTDVILKHMTLANLLVLLSKGIPETLAALGSKHFLDDFGCKLLFYIQKVSRDVSIGTTCILSVFQVIMISPRDSRWAQLQGKAPRYLGTFSILCWVLNMMLNISVPIYTSDRLNNTTSIRHIDHIYCFSVGYSSITYKIYVSLVSFRDGFRLGLMVGSSGSMVLILHRHKQRVRYIHRHDQSARPSPETTATQTILVLVCCFVSLWTLSSVLHSCVAIFNNPSFWLKNTSKLIAACFPALSPYILMSHDSRVSRCFFL", "length": 333, "header": "tr|A0A5G2R1D2-1|A0A5G2R1D2_PIG Isoform 1 of Vomeronasal type-1 receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R1D2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2/entry#A0A5G2R1D2-1", "sequence": { "sequence": "GKAPRDMGTFHILCWTLNMILNILTRSSSPGCDRMDTKDWAIGMIFLLQTTAGLLGNCSLLYHFLFLYLTGGTSRSTDVILKHMTLANLLVLLSKGIPETLAALGSKHFLDDFGCKLLFYIQKVSRDVSIGTTCILSVFQVIMISPRDSRWAQLQGKAPRYLGTFSILCWVLNMMLNISVPIYTSDRLNNTTSIRHIDHIYCFSVGYSSITYKIYVSLVSFRDGFRLGLMVGSSGSMVLILHRHKQRVRYIHRHDQSARPSPETTATQTILVLVCCFVSLWTLSSVLHSCVAIFNNPSFWLKNTSKLIAACFPALSPYILMSHDSRVSRCFFL", "length": 333, "header": "tr|A0A5G2R1D2-1|A0A5G2R1D2_PIG Isoform 1 of Vomeronasal type-1 receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R1D2-1" }, "locus": { "chromosome": "6", "start_pos": 56960715, "end_pos": 56958902, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086104.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086104.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070160.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070160.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2" } ], "pmid": "" }, { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pheromone binding", "id": "GO:0005550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005550", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2" } ], "pmid": "" }, { "name": "pheromone receptor activity", "id": "GO:0016503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016503", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1D2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1D2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 333, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1D2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1D2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1D2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 320, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1I9-1", "uniprot_ac": "A0A5G2R1I9", "uniprot_id": "A0A5G2R1I9_PIG", "mass": { "chemical_mass": 113211.0, "monoisotopic_mass": 113211.0 }, "refseq": { "ac": "XP_020940283", "name": "colorectal mutant cancer protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940283" }, "gene_names": [ { "name": "MCC", "type": "recommended", "evidence": [ { "id": "A0A5G2R1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9" } ] }, { "name": "MCC", "type": "synonym", "evidence": [ { "id": "XP_020940283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940283" } ] } ], "protein_names": [ { "name": "MCC regulator of WNT signaling pathway", "type": "synonym", "evidence": [ { "id": "A0A5G2R1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9/entry#names_and_taxonomy" } ] }, { "name": "colorectal mutant cancer protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020940283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940283" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MCC", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9", "locus": { "chromosome": "2", "start_pos": 116740581, "end_pos": 116287018, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014203", "url": "https://www.ensembl.org/id/ENSSSCG00000014203" } ] } } ], "crossref": [ { "id": "A0A5G2R1I9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1I9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014203", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014203", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515712", "url": "https://www.ncbi.nlm.nih.gov/gene/100515712", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515712", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515712", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R1I9", "url": "https://www.orthodb.org/?gene=A0A5G2R1I9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23347:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23347:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10506", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10506", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020940283", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940283", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R1I9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RLH9", "url": "https://www.uniprot.org/uniprotkb/F1RLH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RLH9-1", "url": "https://www.uniprot.org/uniprotkb/F1RLH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LCC8", "url": "https://www.uniprot.org/uniprotkb/I3LCC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LCC8-1", "url": "https://www.uniprot.org/uniprotkb/I3LCC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAAAAGSASGGSSGGGRGGSSSSDTSSTGEEERMRRLFQTCDGDGDGYISRNDLLMVCRQLNMEESVAEIMNQLGADENGKISFQDFTRCRMQLVREIRKEEVGLSERSDNSCKKKKLRDRIASWPTSSDNSLGAVSAARESWEYDSGARDLQSPDLQTQSALQKLLEYGGSSWHQQAAALHKLLAQSPRFGSSVGGSYLELANTLHLAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSIIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSVDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCCRKKSSCSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTSANRPVNPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSSVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMKLDGSCGGAFAMAGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRTRSLSSTSSGGKDKAGKECADATSPALSLAELRTACSDSELAAEFANAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL", "length": 1016, "header": "tr|A0A5G2R1I9-1|A0A5G2R1I9_PIG Isoform 1 of MCC regulator of WNT signaling pathway OS=Sus scrofa OX=9823 GN=MCC PE=4 SV=2 CANONICAL=A0A5G2R1I9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9/entry#A0A5G2R1I9-1", "sequence": { "sequence": "MMAAAAGSASGGSSGGGRGGSSSSDTSSTGEEERMRRLFQTCDGDGDGYISRNDLLMVCRQLNMEESVAEIMNQLGADENGKISFQDFTRCRMQLVREIRKEEVGLSERSDNSCKKKKLRDRIASWPTSSDNSLGAVSAARESWEYDSGARDLQSPDLQTQSALQKLLEYGGSSWHQQAAALHKLLAQSPRFGSSVGGSYLELANTLHLAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSIIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSVDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCCRKKSSCSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTSANRPVNPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSSVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMKLDGSCGGAFAMAGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRTRSLSSTSSGGKDKAGKECADATSPALSLAELRTACSDSELAAEFANAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL", "length": 1016, "header": "tr|A0A5G2R1I9-1|A0A5G2R1I9_PIG Isoform 1 of MCC regulator of WNT signaling pathway OS=Sus scrofa OX=9823 GN=MCC PE=4 SV=2 CANONICAL=A0A5G2R1I9-1" }, "locus": { "chromosome": "2", "start_pos": 116736913, "end_pos": 116287217, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091476.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091476.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071046.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071046.2" } ] } }, { "isoform_ac": "F1RLH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9/entry#F1RLH9-1", "sequence": { "sequence": "MREHEDVQERTTLRYEERITELHSIIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSVDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCCRKKSSCSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTSANRPVNPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSSVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMKLDGSCGGAFAMAGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRTRSLSSTSSGGKDKAGKECADATSPALSLAELRTACSDSELAAEFANAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL", "length": 766, "header": "tr|F1RLH9-1|A0A5G2R1I9_PIG Computationally mapped isoform of MCC regulator of WNT signaling pathway OS=Sus scrofa OX=9823 GN=MCC PE=4 SV=5 CANONICAL=A0A5G2R1I9-1" }, "locus": { "chromosome": "2", "start_pos": 116736913, "end_pos": 116622422, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015519.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015519.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015109.5", "url": "https://www.ensembl.org/id/ENSSSCP00000015109.5" } ] } }, { "isoform_ac": "I3LCC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9/entry#I3LCC8-1", "sequence": { "sequence": "MNSGVAVKYGNDSSAELSELHLAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSIIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSVDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCCRKKSSCSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTSANRPVNPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSSVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMKLDGSCGGAFAMAGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRTRSLSSTSSGGKDKAGKVGVRGPRLGLIFC", "length": 708, "header": "tr|I3LCC8-1|A0A5G2R1I9_PIG Computationally mapped isoform of MCC regulator of WNT signaling pathway OS=Sus scrofa OX=9823 GN=MCC PE=4 SV=3 CANONICAL=A0A5G2R1I9-1" }, "locus": { "chromosome": "2", "start_pos": 116713094, "end_pos": 116442659, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031945.4", "url": "https://www.ensembl.org/id/ENSSSCT00000031945.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021703.3", "url": "https://www.ensembl.org/id/ENSSSCP00000021703.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LCC8", "url": "https://www.uniprot.org/uniprotkb/I3LCC8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515712", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515712", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of epithelial cell migration", "id": "GO:0010633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010633", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9" } ], "pmid": "" }, { "name": "negative regulation of epithelial cell proliferation", "id": "GO:0050680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050680", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9" } ], "pmid": "" }, { "name": "establishment of protein localization", "id": "GO:0045184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045184", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1I9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1012, "end_pos": 1014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1I9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1016, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1I9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1I9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1I9" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 65, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1012, "end_pos": 1014 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 444, "end_pos": 446 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 681, "end_pos": 683 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1J3-1", "uniprot_ac": "A0A5G2R1J3", "uniprot_id": "A0A5G2R1J3_PIG", "mass": { "chemical_mass": 28513.0, "monoisotopic_mass": 28513.0 }, "refseq": { "ac": "XP_020941865", "name": "metallo-beta-lactamase domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941865" }, "gene_names": [ { "name": "MBLAC1", "type": "recommended", "evidence": [ { "id": "A0A5G2R1J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3" } ] }, { "name": "MBLAC1", "type": "synonym", "evidence": [ { "id": "XP_020941865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941865" } ] } ], "protein_names": [ { "name": "Metallo-beta-lactamase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2R1J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3/entry#names_and_taxonomy" } ] }, { "name": "Endoribonuclease MBLAC1", "type": "synonym", "evidence": [ { "id": "A0A5G2R1J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3/entry#names_and_taxonomy" } ] }, { "name": "metallo-beta-lactamase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_020941865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941865" } ] } ], "function": [ { "annotation": "Endoribonuclease that catalyzes the hydrolysis of histone-coding pre-mRNA 3'-end. Involved in histone pre-mRNA processing during the S-phase of the cell cycle, which is required for entering/progressing through S-phase. Cleaves histone pre-mRNA at a major and a minor cleavage site after the 5'-ACCCA-3' and the 5'-ACCCACA-3' sequence, respectively, and located downstream of the stem-loop. May require the presence of the HDE element located at the histone pre-RNA 3'-end to avoid non-specific cleavage.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3#function" }, { "database": "UniProtKB", "id": "ARBA00045869", "url": "https://www.uniprot.org/uniprotkb/ARBA00045869#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MBLAC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3", "locus": { "chromosome": "3", "start_pos": 8033484, "end_pos": 8031835, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034092", "url": "https://www.ensembl.org/id/ENSSSCG00000034092" } ] } } ], "crossref": [ { "id": "ENSSSCG00000034092", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034092", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07711", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07711", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110259874", "url": "https://www.ncbi.nlm.nih.gov/gene/110259874", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110259874", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259874", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R1J3", "url": "https://www.orthodb.org/?gene=A0A5G2R1J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23200", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23200", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23200:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23200:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020941865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941865", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "68096", "url": "https://www.rhea-db.org/rhea/68096", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R1J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGLVRTEPLRGDTPLLVPGDPYSVVVLLQGYAEPEGVGEALRADGSVTLVLPQAWGPASSHREPSPESHEVKTALEEAARGPILVDTAGPWAREALLGALAGQGLSPGDVTLVVGTHGHSDHIGNLGLFPRAALLVSHDFCLPGGLYLPHGLAEERPLRLGPGLEVWATPGHGGQRDVSVVVAGTTLGTVMVVGDVFERDGDEDSWQALSEDPVAQKRSRKRILGTADVIVPGHGAPFRVIREASPSETEGQRNSQPELVIGDKEPTVHR", "length": 271, "header": "tr|A0A5G2R1J3-1|A0A5G2R1J3_PIG Isoform 1 of Metallo-beta-lactamase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=MBLAC1 PE=3 SV=1 CANONICAL=A0A5G2R1J3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3/entry#A0A5G2R1J3-1", "sequence": { "sequence": "MSGLVRTEPLRGDTPLLVPGDPYSVVVLLQGYAEPEGVGEALRADGSVTLVLPQAWGPASSHREPSPESHEVKTALEEAARGPILVDTAGPWAREALLGALAGQGLSPGDVTLVVGTHGHSDHIGNLGLFPRAALLVSHDFCLPGGLYLPHGLAEERPLRLGPGLEVWATPGHGGQRDVSVVVAGTTLGTVMVVGDVFERDGDEDSWQALSEDPVAQKRSRKRILGTADVIVPGHGAPFRVIREASPSETEGQRNSQPELVIGDKEPTVHR", "length": 271, "header": "tr|A0A5G2R1J3-1|A0A5G2R1J3_PIG Isoform 1 of Metallo-beta-lactamase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=MBLAC1 PE=3 SV=1 CANONICAL=A0A5G2R1J3-1" }, "locus": { "chromosome": "3", "start_pos": 8033183, "end_pos": 8032371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038751.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038751.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073518.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073518.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110259874", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259874", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of G1/S transition of mitotic cell cycle", "id": "GO:1900087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3" } ], "pmid": "" }, { "name": "histone mRNA metabolic process", "id": "GO:0008334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008334", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "68096", "name": "", "equation": "a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end ribonucleotide-RNA + a 5'-end 5'-phospho-ribonucleoside-RNA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "68096", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/68096" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1J3" }, { "id": "SM00849", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00849" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Metallo-beta-lactamase", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 235, "start_aa": "Glu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1K4-1", "uniprot_ac": "A0A5G2R1K4", "uniprot_id": "A0A5G2R1K4_PIG", "mass": { "chemical_mass": 113911.0, "monoisotopic_mass": 113911.0 }, "refseq": {}, "gene_names": [ { "name": "COL19A1", "type": "recommended", "evidence": [ { "id": "A0A5G2R1K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4" } ] } ], "protein_names": [ { "name": "Collagen alpha-1(XIX) chain", "type": "recommended", "evidence": [ { "id": "A0A5G2R1K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4/entry#names_and_taxonomy" } ] }, { "name": "Collagen alpha-1(Y) chain", "type": "synonym", "evidence": [ { "id": "A0A5G2R1K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the sphinteric smooth muscle.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4#function" }, { "database": "UniProtKB", "id": "ARBA00055297", "url": "https://www.uniprot.org/uniprotkb/ARBA00055297#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "COL19A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4", "locus": { "chromosome": "1", "start_pos": 50399969, "end_pos": 50045065, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000044472", "url": "https://www.ensembl.org/id/ENSSSCG00000044472" } ] } } ], "crossref": [ { "id": "A0A5G2R1K4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1K4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044472", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044472", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1442490", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1442490", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8948216", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8948216", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R1K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLAGSWKLWLWAALLLLPASTSVTVRDKPEKQCPVLRTEEHQFTQDNGDKLEVSGFDLGESFSMRRVFCEGDKTCFKLGSSLLIRDTIKVFPKGLPEHFAMVAMFRVRRSTKKERWFLWQVLNQQNMPQVSIVIDGGKKVVEFMFRAAEGDVLNFIFKNRELRSLFDRQWHKLGIGIQSQGISLYMDCNLVASQNTDGKGALDFRGRTIIMARASDGKPVDVELHQLKIYCDLNFIAQETCCEMSDTKCPEQVGFGSTASLSVPAYASRMSAFLPAKQELTDQCQCIPEKGEAGLQGAPGSPGQKGDKGQQGENGLHGVPGLPGQKGEQGFEGLKGEIGEKGEQGEKGDPGLAGVNGQDGSKGDVGPRGPPGPKGEKGDMGPPGPPALTGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQRVQQTLSEYYHKGNLDEHGAGEAGPPGFPGSIGPKGEKGESGEPFTKGEKGDRGEPGITGSQGIKGEPGDPGPPGVIGSPGLMGQQGPTGPMGPRGPPGDVGLPGEHGIPGKPGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGVPGPRGPKGERGLPGVQGSPGDIGPPGVGIPGQTGSQGPAGEPGIQGPRGLPGLPGTPGTPGNDGAPGRDGKPGLPGPPGDPIALPLLGDIGALFKNFCGNCQASVPGLKSNKGEEAGAGEPGKFDSIVHKGDAGPRGPPGIPGREGLKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLLGRTGHPGPTGTKGDKGSEGPPGRPGPPGPPGIPFNEGNGMSSLYKIQGGVNAPSFPGPPGPPGPKGDPGPMGEPGAMGLPGLEGFPGIKGDRGPAGPPGVAGMLGKPGVPGPPGIPGEPGERGPVGDVGFPGPEGPSGKPGINGKDGLPGVQGTMGKPGERGPKGERGDQGIPGDRGPQGERGKPGLPGIKGAIGPVGPPGNKGSPGSPGHQGPPGPGLPGTPADVVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAHGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGNPGLPGTSAPGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHGHPRTDGE", "length": 1132, "header": "tr|A0A5G2R1K4-1|A0A5G2R1K4_PIG Isoform 1 of Collagen alpha-1(XIX) chain OS=Sus scrofa OX=9823 GN=COL19A1 PE=3 SV=1 CANONICAL=A0A5G2R1K4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4/entry#A0A5G2R1K4-1", "sequence": { "sequence": "MRLAGSWKLWLWAALLLLPASTSVTVRDKPEKQCPVLRTEEHQFTQDNGDKLEVSGFDLGESFSMRRVFCEGDKTCFKLGSSLLIRDTIKVFPKGLPEHFAMVAMFRVRRSTKKERWFLWQVLNQQNMPQVSIVIDGGKKVVEFMFRAAEGDVLNFIFKNRELRSLFDRQWHKLGIGIQSQGISLYMDCNLVASQNTDGKGALDFRGRTIIMARASDGKPVDVELHQLKIYCDLNFIAQETCCEMSDTKCPEQVGFGSTASLSVPAYASRMSAFLPAKQELTDQCQCIPEKGEAGLQGAPGSPGQKGDKGQQGENGLHGVPGLPGQKGEQGFEGLKGEIGEKGEQGEKGDPGLAGVNGQDGSKGDVGPRGPPGPKGEKGDMGPPGPPALTGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQRVQQTLSEYYHKGNLDEHGAGEAGPPGFPGSIGPKGEKGESGEPFTKGEKGDRGEPGITGSQGIKGEPGDPGPPGVIGSPGLMGQQGPTGPMGPRGPPGDVGLPGEHGIPGKPGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGVPGPRGPKGERGLPGVQGSPGDIGPPGVGIPGQTGSQGPAGEPGIQGPRGLPGLPGTPGTPGNDGAPGRDGKPGLPGPPGDPIALPLLGDIGALFKNFCGNCQASVPGLKSNKGEEAGAGEPGKFDSIVHKGDAGPRGPPGIPGREGLKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLLGRTGHPGPTGTKGDKGSEGPPGRPGPPGPPGIPFNEGNGMSSLYKIQGGVNAPSFPGPPGPPGPKGDPGPMGEPGAMGLPGLEGFPGIKGDRGPAGPPGVAGMLGKPGVPGPPGIPGEPGERGPVGDVGFPGPEGPSGKPGINGKDGLPGVQGTMGKPGERGPKGERGDQGIPGDRGPQGERGKPGLPGIKGAIGPVGPPGNKGSPGSPGHQGPPGPGLPGTPADVVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAHGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGNPGLPGTSAPGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHGHPRTDGE", "length": 1132, "header": "tr|A0A5G2R1K4-1|A0A5G2R1K4_PIG Isoform 1 of Collagen alpha-1(XIX) chain OS=Sus scrofa OX=9823 GN=COL19A1 PE=3 SV=1 CANONICAL=A0A5G2R1K4-1" }, "locus": { "chromosome": "1", "start_pos": 50394797, "end_pos": 50058400, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074211.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074211.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064402.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064402.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 645, "start_aa": "Thr", "end_pos": 645, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr645", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 648, "start_aa": "Thr", "end_pos": 648, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr648", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 770, "start_aa": "Thr", "end_pos": 770, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr770", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1442490", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-SSC-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-SSC-8948216", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8948216", "resource": "Reactome", "description": "Collagen chain trimerization" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1K4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1132, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1K4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1K4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K4" }, { "id": "SM00210", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00210" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thrombospondin-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 234, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 645, 648, 770 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1K5-1", "uniprot_ac": "A0A5G2R1K5", "uniprot_id": "A0A5G2R1K5_PIG", "mass": { "chemical_mass": 34447.0, "monoisotopic_mass": 34447.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "LINE-1 type transposase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2R1K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K5", "locus": {} } ], "crossref": [ { "id": "A0A5G2R1K5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1K5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045756", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045756", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R1K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVSNETDLCSQTDLEFKREIVKILKELGEDMNSNADTLRKELENIRRSQEKLEHSFTEMQTELGAVKTRMNNAEERIIIPDRIMEITQSSQQTENQIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENILEEIIDGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISDDFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKIFSNKQKLKEYSNTKPRLKEILKGLL", "length": 295, "header": "tr|A0A5G2R1K5-1|A0A5G2R1K5_PIG Isoform 1 of LINE-1 type transposase domain-containing protein 1 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R1K5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K5/entry#A0A5G2R1K5-1", "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVSNETDLCSQTDLEFKREIVKILKELGEDMNSNADTLRKELENIRRSQEKLEHSFTEMQTELGAVKTRMNNAEERIIIPDRIMEITQSSQQTENQIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENILEEIIDGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISDDFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKIFSNKQKLKEYSNTKPRLKEILKGLL", "length": 295, "header": "tr|A0A5G2R1K5-1|A0A5G2R1K5_PIG Isoform 1 of LINE-1 type transposase domain-containing protein 1 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R1K5-1" }, "locus": { "chromosome": "1", "start_pos": 71457349, "end_pos": 71456465, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072837.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072837.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068077.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068077.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1K5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 295, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1K5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1K5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K5" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 226, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R1K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K5" }, { "id": "PF17490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element dsRBD-like", "eco_id": "ECO_0000259", "start_pos": 230, "end_pos": 292, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 213, "end_pos": 215 }, { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1K7-1", "uniprot_ac": "A0A5G2R1K7", "uniprot_id": "A0A5G2R1K7_PIG", "mass": { "chemical_mass": 34891.0, "monoisotopic_mass": 34891.0 }, "refseq": { "ac": "XP_003124227", "name": "olfactory receptor 140-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124227" }, "gene_names": [ { "name": "LOC100517394", "type": "recommended", "evidence": [ { "id": "A0A5G2R1K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7" } ] }, { "name": "LOC100517394", "type": "synonym", "evidence": [ { "id": "XP_003124227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124227" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R1K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 140-like", "type": "synonym", "evidence": [ { "id": "XP_003124227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124227" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100517394", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7", "locus": {} } ], "crossref": [ { "id": "A0A5G2R1K7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1K7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100517394", "url": "https://www.ncbi.nlm.nih.gov/gene/100517394", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517394", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517394", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ATYHADK", "url": "https://omabrowser.org/oma/group/ATYHADK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R1K7", "url": "https://www.orthodb.org/?gene=A0A5G2R1K7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003124227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124227", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R1K7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFLTLPNNVTEFVLLGLTQNPHLRKILFMVFLSIFLFTLLANLFIVITISLSPTLSAPMYFFLTYLAFIDASFSSVTTPKMIFDLLYQRTTISWGGCLTQLFLEHFLGGSEMIVLIAMAYDRYVAICKPLHYTTIMRHGFCQLLVVVAWVGGILHATVQIIFTCELTFCGPNVIDHFMCEFFSLLELACSNTYRLGIVVATNTGGMCLLIFSILIVSYIVILSSLKSHGSEGRYKALSTCGSHFTVVLLFFVPSFFIYIRPVATYHADKLVCLFYATFTPMLNPIIYTVRNQEVKIAMKRLLKRRVT", "length": 308, "header": "tr|A0A5G2R1K7-1|A0A5G2R1K7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100517394 PE=3 SV=1 CANONICAL=A0A5G2R1K7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7/entry#A0A5G2R1K7-1", "sequence": { "sequence": "MDFLTLPNNVTEFVLLGLTQNPHLRKILFMVFLSIFLFTLLANLFIVITISLSPTLSAPMYFFLTYLAFIDASFSSVTTPKMIFDLLYQRTTISWGGCLTQLFLEHFLGGSEMIVLIAMAYDRYVAICKPLHYTTIMRHGFCQLLVVVAWVGGILHATVQIIFTCELTFCGPNVIDHFMCEFFSLLELACSNTYRLGIVVATNTGGMCLLIFSILIVSYIVILSSLKSHGSEGRYKALSTCGSHFTVVLLFFVPSFFIYIRPVATYHADKLVCLFYATFTPMLNPIIYTVRNQEVKIAMKRLLKRRVT", "length": 308, "header": "tr|A0A5G2R1K7-1|A0A5G2R1K7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100517394 PE=3 SV=1 CANONICAL=A0A5G2R1K7-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 464354, "end_pos": 463431, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070876.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070876.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070999.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070999.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517394", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517394", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1K7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1K7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 308, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1K7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1K7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1K7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 288, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1Q0-1", "uniprot_ac": "A0A5G2R1Q0", "uniprot_id": "A0A5G2R1Q0_PIG", "mass": { "chemical_mass": 36290.0, "monoisotopic_mass": 36290.0 }, "refseq": { "ac": "XP_001926373", "name": "olfactory receptor 1361-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926373" }, "gene_names": [ { "name": "LOC100156904", "type": "recommended", "evidence": [ { "id": "A0A5G2R1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0" } ] }, { "name": "LOC100156904", "type": "synonym", "evidence": [ { "id": "XP_001926373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926373" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1361-like", "type": "synonym", "evidence": [ { "id": "XP_001926373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926373" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Q0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Q0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100156904", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0", "locus": {} } ], "crossref": [ { "id": "A0A5G2R1Q0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1Q0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15235", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15235", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156904", "url": "https://www.ncbi.nlm.nih.gov/gene/100156904", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156904", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156904", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R1Q0", "url": "https://www.orthodb.org/?gene=A0A5G2R1Q0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001926373", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926373", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R1Q0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTRNRTEVTEFVLLGLSIWPEMQPFIFGIVLIMYLVAVMGNSLLVIVALSDPKLQTPMYFLLSHLSFIDIFLTSITVPQMLAHMLSGNRTISFNCCMIQLFFFMAVGSMEGHLLAAMAYDRYVAICDPLRYSAIISHRLCLRITLTSWVVVSLNSLLYSVLVTRLTFCGNQVTHFFCDITPLLKLSCTRPVVNEMLIFTEGVAVVVSPFFFILGSYTRIGIAIAHMHSVAVLRKALSTCSSHILVVLLLYGSVIRMYLRPSSSYDLDQDCQVAIFYTVVTPMLNPLIYSLRNQEVKGALQRLFRKFCISGNFQLGSQAKRK", "length": 322, "header": "tr|A0A5G2R1Q0-1|A0A5G2R1Q0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100156904 PE=3 SV=1 CANONICAL=A0A5G2R1Q0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0/entry#A0A5G2R1Q0-1", "sequence": { "sequence": "MTTRNRTEVTEFVLLGLSIWPEMQPFIFGIVLIMYLVAVMGNSLLVIVALSDPKLQTPMYFLLSHLSFIDIFLTSITVPQMLAHMLSGNRTISFNCCMIQLFFFMAVGSMEGHLLAAMAYDRYVAICDPLRYSAIISHRLCLRITLTSWVVVSLNSLLYSVLVTRLTFCGNQVTHFFCDITPLLKLSCTRPVVNEMLIFTEGVAVVVSPFFFILGSYTRIGIAIAHMHSVAVLRKALSTCSSHILVVLLLYGSVIRMYLRPSSSYDLDQDCQVAIFYTVVTPMLNPLIYSLRNQEVKGALQRLFRKFCISGNFQLGSQAKRK", "length": 322, "header": "tr|A0A5G2R1Q0-1|A0A5G2R1Q0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100156904 PE=3 SV=1 CANONICAL=A0A5G2R1Q0-1" }, "locus": { "chromosome": "AEMK02000598.1", "start_pos": 457540, "end_pos": 456575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006115.3", "url": "https://www.ensembl.org/id/ENSSSCT00000006115.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071044.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071044.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Q0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156904", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156904", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Q0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Q0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Q0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Q0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1Q0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 322, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1Q0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1Q0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1Y7-1", "uniprot_ac": "A0A5G2R1Y7", "uniprot_id": "A0A5G2R1Y7_PIG", "mass": { "chemical_mass": 35876.0, "monoisotopic_mass": 35876.0 }, "refseq": { "ac": "XP_003123633", "name": "olfactory receptor 2L3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123633" }, "gene_names": [ { "name": "LOC100521433", "type": "recommended", "evidence": [ { "id": "A0A5G2R1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7" } ] }, { "name": "LOC100521433", "type": "synonym", "evidence": [ { "id": "XP_003123633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123633" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2L3-like", "type": "synonym", "evidence": [ { "id": "XP_003123633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123633" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Y7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Y7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100521433", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7", "locus": {} } ], "crossref": [ { "id": "A0A5G2R1Y7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1Y7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521433", "url": "https://www.ncbi.nlm.nih.gov/gene/100521433", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521433", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521433", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R1Y7", "url": "https://www.orthodb.org/?gene=A0A5G2R1Y7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003123633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123633", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R1Y7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENYNETSTDFILLGLFPPSRIGLFLFILIVLIFLVALFGNLFMILLIFLDIHLHTPMYYLLSQLSFIDLNYISTIVPKMAYNFLFGNRSISFIGCGVQSFFFLTLGGAETLLLTSMSYDRYVAICFPLHYPIRISRRLCVLMIIGSWIMGSINSCAHTIYALHIPYCRSRAINHFFCDVPAMLTLACMDTWVYEYTVFVSTTLFLLLPFIVILCSYGHVLLAVHRMQSVEGRKKAYATCSTHLTVVTFYYVPFAYTYLRPRSLRSPVEDKVLAVFYTMLTPMLNPVIYSLRNKEVMGALRRLIQRIGSVKM", "length": 312, "header": "tr|A0A5G2R1Y7-1|A0A5G2R1Y7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100521433 PE=3 SV=1 CANONICAL=A0A5G2R1Y7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7/entry#A0A5G2R1Y7-1", "sequence": { "sequence": "MENYNETSTDFILLGLFPPSRIGLFLFILIVLIFLVALFGNLFMILLIFLDIHLHTPMYYLLSQLSFIDLNYISTIVPKMAYNFLFGNRSISFIGCGVQSFFFLTLGGAETLLLTSMSYDRYVAICFPLHYPIRISRRLCVLMIIGSWIMGSINSCAHTIYALHIPYCRSRAINHFFCDVPAMLTLACMDTWVYEYTVFVSTTLFLLLPFIVILCSYGHVLLAVHRMQSVEGRKKAYATCSTHLTVVTFYYVPFAYTYLRPRSLRSPVEDKVLAVFYTMLTPMLNPVIYSLRNKEVMGALRRLIQRIGSVKM", "length": 312, "header": "tr|A0A5G2R1Y7-1|A0A5G2R1Y7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100521433 PE=3 SV=1 CANONICAL=A0A5G2R1Y7-1" }, "locus": { "chromosome": "2", "start_pos": 55310530, "end_pos": 55309595, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073198.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073198.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071124.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071124.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Y7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521433", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521433", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Y7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Y7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Y7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Y7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1Y7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1Y7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1Y7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Y7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1Z0-1", "uniprot_ac": "A0A5G2R1Z0", "uniprot_id": "A0A5G2R1Z0_PIG", "mass": { "chemical_mass": 27995.0, "monoisotopic_mass": 27995.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100515533", "type": "recommended", "evidence": [ { "id": "A0A5G2R1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0" } ] } ], "protein_names": [ { "name": "Histone RNA hairpin-binding protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0/entry#names_and_taxonomy" } ] }, { "name": "Histone stem-loop-binding protein", "type": "synonym", "evidence": [ { "id": "A0A5G2R1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). Plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. Involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. Binds to the 5' side of the stem-loop structure of histone pre-mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0#function" }, { "database": "UniProtKB", "id": "ARBA00057687", "url": "https://www.uniprot.org/uniprotkb/ARBA00057687#function" }, { "database": "UniProtKB", "id": "I3LHJ1", "url": "https://www.uniprot.org/uniprotkb/I3LHJ1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100515533", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0", "locus": {} } ], "crossref": [ { "id": "A0A5G2R1Z0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1Z0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000023691", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000023691", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR026502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PPVWQML", "url": "https://omabrowser.org/oma/group/PPVWQML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR17408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17408:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17408:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15247", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15247", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R1Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LHJ1", "url": "https://www.uniprot.org/uniprotkb/I3LHJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LHJ1-1", "url": "https://www.uniprot.org/uniprotkb/I3LHJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNKSEIQPLSLKDSKSEIQPLAGVRILVAEKYSIISLVFYTLFFFFFFFLFFAFLPFLGPLLRICFLRKEVCEESLSSRIEMVSVGVSTEPCRARWEVETDKTILQRRQKQIDYGKRTPGYQSFLQQVPKAQRLPGLHPQTPNKNRRYSRRSWDAQIRQWRRALHSWDPPTSLCRWGMENLLEPMDSSPLQPSGNLDGDQKGTQLADLVAPASSLSWICEEDPHHWLYVLADYNYLSQT", "length": 240, "header": "tr|A0A5G2R1Z0-1|A0A5G2R1Z0_PIG Isoform 1 of Histone RNA hairpin-binding protein OS=Sus scrofa OX=9823 GN=LOC100515533 PE=3 SV=1 CANONICAL=A0A5G2R1Z0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0/entry#A0A5G2R1Z0-1", "sequence": { "sequence": "MRNKSEIQPLSLKDSKSEIQPLAGVRILVAEKYSIISLVFYTLFFFFFFFLFFAFLPFLGPLLRICFLRKEVCEESLSSRIEMVSVGVSTEPCRARWEVETDKTILQRRQKQIDYGKRTPGYQSFLQQVPKAQRLPGLHPQTPNKNRRYSRRSWDAQIRQWRRALHSWDPPTSLCRWGMENLLEPMDSSPLQPSGNLDGDQKGTQLADLVAPASSLSWICEEDPHHWLYVLADYNYLSQT", "length": 240, "header": "tr|A0A5G2R1Z0-1|A0A5G2R1Z0_PIG Isoform 1 of Histone RNA hairpin-binding protein OS=Sus scrofa OX=9823 GN=LOC100515533 PE=3 SV=1 CANONICAL=A0A5G2R1Z0-1" }, "locus": { "chromosome": "2", "start_pos": 140329572, "end_pos": 140326046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069243.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069243.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071201.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071201.1" } ] } }, { "isoform_ac": "I3LHJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0/entry#I3LHJ1-1", "sequence": { "sequence": "MEYLPPVWQMLRQDRICFLRKEVCEESLSSRIEMVSVGVSTEPCRARWEVETDKTILQRRQKQIDYGKRTPGYQSFLQQVPKAQRLPGLHPQTPNKNRRYSRRSWDAQIRQWRRALHSWPPNQPLQAEGWGMENLLEPMDSSPLQPSGNLDGDQKGTQLADLVAPASSLSWICEEDPHHWLYVLADYNYLSQT", "length": 193, "header": "tr|I3LHJ1-1|A0A5G2R1Z0_PIG Computationally mapped isoform of Histone RNA hairpin-binding protein OS=Sus scrofa OX=9823 GN=LOC100515533 PE=3 SV=2 CANONICAL=A0A5G2R1Z0-1" }, "locus": { "chromosome": "2", "start_pos": 140329572, "end_pos": 140324795, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024036.3", "url": "https://www.ensembl.org/id/ENSSSCT00000024036.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023537.2", "url": "https://www.ensembl.org/id/ENSSSCP00000023537.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LHJ1", "url": "https://www.uniprot.org/uniprotkb/I3LHJ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "histone pre-mRNA 3'end processing complex", "id": "GO:0071204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071204", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "histone pre-mRNA stem-loop binding", "id": "GO:0071207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071207", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA 3'-end processing by stem-loop binding and cleavage", "id": "GO:0006398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006398", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1Z0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 240, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1Z0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1Z0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z0" }, { "id": "PF15247", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15247" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histone RNA hairpin-binding protein RNA-binding", "eco_id": "ECO_0000259", "start_pos": 101, "end_pos": 170, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R1Z1-1", "uniprot_ac": "A0A5G2R1Z1", "uniprot_id": "A0A5G2R1Z1_PIG", "mass": { "chemical_mass": 20981.0, "monoisotopic_mass": 20981.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R1Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1", "locus": {} } ], "crossref": [ { "id": "A0A5G2R1Z1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1Z1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R1Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPRANGTLSGKSLQEFVLEGFQGGLQTPALLFALFLALYLAAVLGNLTMIVVITLDARLHSPMYFFLKNLSFLDLCYSSVIYPKALANVLSSAKVISFGGCASQFFLISLMITTEGFLLAVMAYDRFLAICSPLHYPITMCPSACARLVLGCYGGGCLNAILQTSFTFSLPFCSSNHIDHFFCDVPAAPARLC", "length": 194, "header": "tr|A0A5G2R1Z1-1|A0A5G2R1Z1_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R1Z1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1/entry#A0A5G2R1Z1-1", "sequence": { "sequence": "MTPRANGTLSGKSLQEFVLEGFQGGLQTPALLFALFLALYLAAVLGNLTMIVVITLDARLHSPMYFFLKNLSFLDLCYSSVIYPKALANVLSSAKVISFGGCASQFFLISLMITTEGFLLAVMAYDRFLAICSPLHYPITMCPSACARLVLGCYGGGCLNAILQTSFTFSLPFCSSNHIDHFFCDVPAAPARLC", "length": 194, "header": "tr|A0A5G2R1Z1-1|A0A5G2R1Z1_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R1Z1-1" }, "locus": { "chromosome": "AEMK02000402.1", "start_pos": 24376, "end_pos": 23795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096801.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096801.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080325.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080325.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R1Z1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 194, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R1Z1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R1Z1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R1Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Z1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 194, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 47, "end_pos": 49 }, { "start_pos": 6, "end_pos": 8 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R207-1", "uniprot_ac": "A0A5G2R207", "uniprot_id": "A0A5G2R207_PIG", "mass": { "chemical_mass": 49791.0, "monoisotopic_mass": 49791.0 }, "refseq": {}, "gene_names": [ { "name": "GOLM2", "type": "recommended", "evidence": [ { "id": "A0A5G2R207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207" } ] } ], "protein_names": [ { "name": "Protein GOLM2", "type": "recommended", "evidence": [ { "id": "A0A5G2R207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207/entry#names_and_taxonomy" } ] }, { "name": "Golgi membrane protein 2", "type": "synonym", "evidence": [ { "id": "A0A5G2R207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R207", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GOLM2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207", "locus": { "chromosome": "1", "start_pos": 127131105, "end_pos": 127238601, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000023996", "url": "https://www.ensembl.org/id/ENSSSCG00000023996" } ] } } ], "crossref": [ { "id": "A0A5G2R207", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R207", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000023996", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000023996", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR026139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "XRFFDEN", "url": "https://omabrowser.org/oma/group/XRFFDEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R207", "url": "https://www.orthodb.org/?gene=A0A5G2R207", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15896", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15896", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15896:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15896:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R207", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R207-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3J4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SN03", "url": "https://www.uniprot.org/uniprotkb/F1SN03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SN03-1", "url": "https://www.uniprot.org/uniprotkb/F1SN03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LHM7", "url": "https://www.uniprot.org/uniprotkb/I3LHM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LHM7-1", "url": "https://www.uniprot.org/uniprotkb/I3LHM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGFGANRRAGRLPSFVLVVLLVVIAVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDSHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIRHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQIKELRAQHEENIKKLADQFLQEQKQETHKFESKNRNELDINNHAVPRNIPKVEENAADKNKEPSSNHNPHGKEQIKGGGDAGMPEIEENDVAKAEDLPTGLKKPPLSFSQYESHQTISHLPTGQPLSPNIVQDSHVNHNGNPRTSKQNPSNPLQRIIPGPNLENEPRIQADILKQATKDRAGDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEERELQMDPADYGKQRFNDVL", "length": 436, "header": "tr|A0A5G2R207-1|A0A5G2R207_PIG Isoform 1 of Protein GOLM2 OS=Sus scrofa OX=9823 GN=GOLM2 PE=1 SV=1 CANONICAL=A0A5G2R207-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R207-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207/entry#A0A5G2R207-1", "sequence": { "sequence": "MVGFGANRRAGRLPSFVLVVLLVVIAVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDSHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIRHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQIKELRAQHEENIKKLADQFLQEQKQETHKFESKNRNELDINNHAVPRNIPKVEENAADKNKEPSSNHNPHGKEQIKGGGDAGMPEIEENDVAKAEDLPTGLKKPPLSFSQYESHQTISHLPTGQPLSPNIVQDSHVNHNGNPRTSKQNPSNPLQRIIPGPNLENEPRIQADILKQATKDRAGDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEERELQMDPADYGKQRFNDVL", "length": 436, "header": "tr|A0A5G2R207-1|A0A5G2R207_PIG Isoform 1 of Protein GOLM2 OS=Sus scrofa OX=9823 GN=GOLM2 PE=1 SV=1 CANONICAL=A0A5G2R207-1" }, "locus": { "chromosome": "1", "start_pos": 127238164, "end_pos": 127133634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088308.1", "url": "https://www.ensembl.org/id/ENSSSCT00000088308.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071144.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071144.1" } ] } }, { "isoform_ac": "A0A5G2R3J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207/entry#A0A5G2R3J4-1", "sequence": { "sequence": "MVGFGANRRAGRLPSFVLVVLLVVIAVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDSHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIRHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQIKELRAQHEENIKKLADQFLQEQKQETHKFESKNRNELDINNHAVPRNIPKVEENAADKNKEPSSNHNPHGKEQIKGGGDAGMPEIEENDVAKAEDLPTGLKKPPLSFSQYESHQTISHLPTGQPLSPNIVQDSHVNHNGNPRTSKQNPSNPLQRIIPGPNLENEPRIQADILKQATKDRAGDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQGERGPGLHAVTMKSTSKFFG", "length": 433, "header": "tr|A0A5G2R3J4-1|A0A5G2R3J4_PIG Computationally mapped isoform of Protein GOLM2 OS=Sus scrofa OX=9823 GN=GOLM2 PE=1 SV=1 CANONICAL=A0A5G2R207-1" }, "locus": { "chromosome": "1", "start_pos": 127238164, "end_pos": 127140742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079989.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079989.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071773.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071773.1" } ] } }, { "isoform_ac": "F1SN03-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207/entry#F1SN03-1", "sequence": { "sequence": "MADIRHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQIKELRAQHEENIKKLADQFLQEQKQETHKFESKNRNELDINNHAVPRNIPKVEENAADKNKEPSSNHNPHGKEQIKGGGDAGMPEIEENDVAKAEDLPTGLKKPPLSFSQYESHQTISHLPTGQPLSPNIVQDSHVNHNGNPRTSKQNPSNPLQRIIPGPNLENEPRIQADILKQATKDRAGDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEERELQMDPADYGKQRFNDVL", "length": 317, "header": "tr|F1SN03-1|F1SN03_PIG Computationally mapped isoform of Protein GOLM2 OS=Sus scrofa OX=9823 GN=GOLM2 PE=3 SV=3 CANONICAL=A0A5G2R207-1" }, "locus": { "chromosome": "1", "start_pos": 127207665, "end_pos": 127133634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005183.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005183.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005057.4", "url": "https://www.ensembl.org/id/ENSSSCP00000005057.4" } ] } }, { "isoform_ac": "I3LHM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207/entry#I3LHM7-1", "sequence": { "sequence": "MVGFGANRRAGRLPSFVLVVLLVVIAVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDSHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIRHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQIKELRAQHEENIKKLADQFLQEQKQETHKFESKNRNELDINNHAVPRNIPKVEENAADKNKEPSSNHNPHGKEQIKGGGDAGMPEIEENDVAKAEDLPTGLKKPPLSFSQYESHQTISHLPTGQPLSPNIVQDSHVNHNGNPRTSKQNPSNPLQRIIPGPNLENEPRIQADILKQATKDRAGDFHKLKQNDEERELQMDPADYGKQRFNDVL", "length": 380, "header": "tr|I3LHM7-1|A0A5G2R207_PIG Computationally mapped isoform of Protein GOLM2 OS=Sus scrofa OX=9823 GN=GOLM2 PE=1 SV=2 CANONICAL=A0A5G2R207-1" }, "locus": { "chromosome": "1", "start_pos": 127238164, "end_pos": 127133634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025826.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025826.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023574.2", "url": "https://www.ensembl.org/id/ENSSSCP00000023574.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LHM7", "url": "https://www.uniprot.org/uniprotkb/I3LHM7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PFD3-1", "protein_name": "Protein GOLM2", "gene_name": "CASC4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVGFGANRRGGRLPSFLLAALLLVIAVLAFNCWNAASRQAVLREELAELQSQAKRTEVARGRLEKRNSDLLGRVDSHRKQLEQKEADYSQLSSQLQARDGQVKRCEDSRVKLQNNISYQMADIHRLKEQLAELRQEFIRQEDQLHEYKKNNTYLTRRLEYDSLQCGQQIKEMRIQHEENIKKLMDQIVREQKATQRIQSSKDAEVNPNGDNQPISKTVPEMEVKNAENNELPSDRVVNGKEKVKPGGDAGMPEIEDNDPAKAEDTPTAIKKPLISAPRSDNHHQADVNLPTEQPHAPNLAPGLHGDNDGNADIAKEIPPNSLQHLNFGENMDSQNENKIEADHLKLQKGRAVGLQKMKQSRFFDENESPVDPQQGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEERDLQNDLVDYSKPRFGDGVL", "length": 439 }, "evidence": [ { "id": "A0A5G2R207", "url": "https://omabrowser.org/oma/group/A0A5G2R207/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2VE10-1", "protein_name": "Protein GOLM2", "gene_name": "GOLM2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVGFGANRRAGRLPSLVLAVLLVVIAVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDSHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQIKELRAQHEENIKKLADQFLQEQKQEAHKFESKGGNELDTDNHAVPKNIPEVAENGAGKNEEPSSHHIPHGKEQIKRGGDAGMPGIEENDLAKAEDVPVALKKPPVSFSQYESHQVISHLPTGQPLSPNMVPDSHINHNGNSRTSKQNPSNPLQRLIPGPNLENEPRIQAEVLKQATKDRAGDFHKLKQNDEERELQMDPADYGKQRFNDAL", "length": 380 }, "evidence": [ { "id": "A0A5G2R207", "url": "https://omabrowser.org/oma/group/A0A5G2R207/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7FBP9-1", "protein_name": "Protein GOLM2", "gene_name": "golm2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIGFGAIRRGGRLPSFILIALLVVIVILSFNYWSVSTKHARLLDELAEVQTQVKRTDAARSRLEKRNSELMMQVDTHRKQIDLKDGDYSALQNKLQARDALVKTCTDDKNKLQNDVSAQMSEIHRLKEQVKELRQEVIRQEDQQREVRKNSTNLEKKLEYESLQCGRQIAELKAEYEESKKRVEEEAAKLRQSLLENRNADSVVQHVDLDLDQSNKRKEKEDTAERHTVAARRNDVPVLKDDLGKPGSDAGMPGIEDSEVGKIDDSQFAIKKPAITPQKHMEPAEAAAMLKEERAGFGAGAGARLGDDLARGQPLDRPDMPRDENLRLMNRDIPVQQQVPQPVVIKPMLFDEDNKAGIKADEFGEQRRQVGAEGLKAEGVGIPPPPNPVQVHAKPIDPHNGRDPVAADPPRHRQSRFFDENESPVDPQHGNKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEDRDAPGERNVDYGKRHQANDVL", "length": 495 }, "evidence": [ { "id": "A0A5G2R207", "url": "https://omabrowser.org/oma/group/A0A5G2R207/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6P2L7-1", "protein_name": "Protein GOLM2", "gene_name": "Golm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGFGANRRAGRLPSFVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAKEGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQIKELRAQHEENIKKLADQFLQEQKETHKIQSNDGKELGRNDHGAPKNIPNVPENDANKNEDPSSNHLPHGKEQLKRVGDAGMPGVEENDLAKVDELPAALKKPPVLASQHESHQTISHLPTGQPLSPNMAPGSHLNQNENPSTSKQNPSNPLQHIIPGPNLDREPRIQTDTLKQATRDRANDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEERELQMDPADYGKQRFSDVL", "length": 435 }, "evidence": [ { "id": "A0A5G2R207", "url": "https://omabrowser.org/oma/group/A0A5G2R207/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6P4E1-4", "protein_name": "Protein GOLM2", "gene_name": "GOLM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPPDSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEERELQMDPADYGKQHFNDVL", "length": 436 }, "evidence": [ { "id": "A0A5G2R207", "url": "https://omabrowser.org/oma/group/A0A5G2R207/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R207", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R207", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R207" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R207-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 436, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R207-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R207" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 364, "end_pos": 366 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R210-1", "uniprot_ac": "A0A5G2R210", "uniprot_id": "A0A5G2R210_PIG", "mass": { "chemical_mass": 37774.0, "monoisotopic_mass": 37774.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100623107", "type": "recommended", "evidence": [ { "id": "A0A5G2R210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R210", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R210", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100623107", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210", "locus": {} } ], "crossref": [ { "id": "A0A5G2R210", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R210", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041359", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041359", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ATTECFI", "url": "https://omabrowser.org/oma/group/ATTECFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R210", "url": "https://www.orthodb.org/?gene=A0A5G2R210", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R210", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R210-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDDCPFYTCYILFQRTSFKNMETKNATELTEFVLTGLTYQQECKIPLFLLFLVIYIITIMGNLGLIALICNDLQLHIPMYLFLGNLAFVDTWLSSTVTPRMLVNILTKSKMISLSECMTQCFSFVVSATTECFLLATMAYDRCVAICNPLLYPMIMTNRLCMRMLISSFVGGLLHALIHTGFLFRLTFCNSNVIHHFYCDIMPLFKISCTDPSINALMIFVFSGSIQVFTILTVLVSYTQVLFTILKKKSLQGIRKAFSTCGAHLLSVSLYYGPLLFMYVRPGSEQAGEQDMIDSLFYTVIIPFINPIIYSLRNKSVIDSLRKTLKRNTCI", "length": 332, "header": "tr|A0A5G2R210-1|A0A5G2R210_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100623107 PE=3 SV=1 CANONICAL=A0A5G2R210-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R210-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210/entry#A0A5G2R210-1", "sequence": { "sequence": "MVDDCPFYTCYILFQRTSFKNMETKNATELTEFVLTGLTYQQECKIPLFLLFLVIYIITIMGNLGLIALICNDLQLHIPMYLFLGNLAFVDTWLSSTVTPRMLVNILTKSKMISLSECMTQCFSFVVSATTECFLLATMAYDRCVAICNPLLYPMIMTNRLCMRMLISSFVGGLLHALIHTGFLFRLTFCNSNVIHHFYCDIMPLFKISCTDPSINALMIFVFSGSIQVFTILTVLVSYTQVLFTILKKKSLQGIRKAFSTCGAHLLSVSLYYGPLLFMYVRPGSEQAGEQDMIDSLFYTVIIPFINPIIYSLRNKSVIDSLRKTLKRNTCI", "length": 332, "header": "tr|A0A5G2R210-1|A0A5G2R210_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100623107 PE=3 SV=1 CANONICAL=A0A5G2R210-1" }, "locus": { "chromosome": "13", "start_pos": 161470159, "end_pos": 161469164, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077186.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077186.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070385.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070385.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R210", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R210", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R210", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R210", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R210", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R210-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 332, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R210-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R210" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R210" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 311, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 }, { "start_pos": 315, "end_pos": 317 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R224-1", "uniprot_ac": "A0A5G2R224", "uniprot_id": "A0A5G2R224_PIG", "mass": { "chemical_mass": 35745.0, "monoisotopic_mass": 35745.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R224/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R224", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R224#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R224", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R224" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R224", "locus": {} } ], "crossref": [ { "id": "A0A5G2R224", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R224", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R224", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R224", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R224-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R224-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRKPMEGANQSVVSEFVFLGITNSWEIQLLLLVFSSMFYMASMMGNSLIMLTVTSDPHLHSPMYFLLANLSFIDMGVSSVTSPKMIYDLFRKCKVISFTGCIAQIFFIHVIGGVEMVLLIAMAFDRYVAICKPLHYLTIMSPRLCISFLVAAWMTGLIHSMVQLAFVVNLPFCGPNVLDSFYCDLPQFIKLACIDADQLEFMVMANSGFISVGSFFILIISYIVIILTVKKQSSLRSSKALSTLSAHITVVILFFGPLIFVYTWPSLSTPLDKFLAIFDAVLTPFLNSVIYTFRNQEMKVAMRRVCRQLMSYRKIS", "length": 317, "header": "tr|A0A5G2R224-1|A0A5G2R224_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R224-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R224-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R224/entry#A0A5G2R224-1", "sequence": { "sequence": "MVRKPMEGANQSVVSEFVFLGITNSWEIQLLLLVFSSMFYMASMMGNSLIMLTVTSDPHLHSPMYFLLANLSFIDMGVSSVTSPKMIYDLFRKCKVISFTGCIAQIFFIHVIGGVEMVLLIAMAFDRYVAICKPLHYLTIMSPRLCISFLVAAWMTGLIHSMVQLAFVVNLPFCGPNVLDSFYCDLPQFIKLACIDADQLEFMVMANSGFISVGSFFILIISYIVIILTVKKQSSLRSSKALSTLSAHITVVILFFGPLIFVYTWPSLSTPLDKFLAIFDAVLTPFLNSVIYTFRNQEMKVAMRRVCRQLMSYRKIS", "length": 317, "header": "tr|A0A5G2R224-1|A0A5G2R224_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R224-1" }, "locus": { "chromosome": "7", "start_pos": 79767693, "end_pos": 79766743, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075739.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075739.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071159.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071159.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R224", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R224" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R224", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R224" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R224", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R224" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R224", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R224" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R224-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 317, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R224-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R224" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R224" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 292, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R236-1", "uniprot_ac": "A0A5G2R236", "uniprot_id": "A0A5G2R236_PIG", "mass": { "chemical_mass": 34629.0, "monoisotopic_mass": 34629.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "L1 transposable element RRM domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R236/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R236", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R236" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R236", "locus": {} } ], "crossref": [ { "id": "A0A5G2R236", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R236", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000047248", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000047248", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R236", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R236", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R236-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R236-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSQTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEEQISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKQANLRIIGIPEGVEKDKGMGNIFEEIIDGNFPNLKDTGFKIQEAQRAPYKLNPNRPTPRHIIIKMARVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKLFPNKQKLKEYSNTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2R236-1|A0A5G2R236_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R236-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R236-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R236/entry#A0A5G2R236-1", "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSQTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEEQISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKQANLRIIGIPEGVEKDKGMGNIFEEIIDGNFPNLKDTGFKIQEAQRAPYKLNPNRPTPRHIIIKMARVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKLFPNKQKLKEYSNTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2R236-1|A0A5G2R236_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R236-1" }, "locus": { "chromosome": "13", "start_pos": 16471381, "end_pos": 16470494, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069094.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069094.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068257.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068257.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R236", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R236" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R236", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R236" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R236", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R236" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R236", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R236" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R236-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 296, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R236-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R236" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R236" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 227, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R236" }, { "id": "PF17490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element dsRBD-like", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 293, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2A0-1", "uniprot_ac": "A0A5G2R2A0", "uniprot_id": "A0A5G2R2A0_PIG", "mass": { "chemical_mass": 36001.0, "monoisotopic_mass": 36001.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "A0A5G2R2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "A0A5G2R2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0", "locus": {} } ], "crossref": [ { "id": "A0A5G2R2A0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2A0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000042403", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042403", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R2A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSAVRNTPLRGPELPLDGPPLGRAPALQPRRTSPPAPAPEPAALPSPCLSRLPKPLEGLGLEDPRTRRPGTTEVGPTSHAPRVWFVLDALGLACATATWLLVLSEGVVLLCAWLLPARRPAYSLAHGSLFHLLAFLALASHARTMLTDPGALPAGALAQPGPTPSGPCCPLCGAIQPPGAHHCSVCGRCIRRRDHHCPWVNNCVGEDNRKFFLLFTLYTALAALHVLLLLGVPALRAHALGQWNLRTTVEPQGSLIYLFLVALNGFVFAAVMFTIQIHAILTDRPGIQPPQRQSGAPGRASPWKNLQAVLGHRVSLAWISPFASPDPQAASEPPNIV", "length": 338, "header": "tr|A0A5G2R2A0-1|A0A5G2R2A0_PIG Isoform 1 of Palmitoyltransferase OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R2A0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0/entry#A0A5G2R2A0-1", "sequence": { "sequence": "MSSAVRNTPLRGPELPLDGPPLGRAPALQPRRTSPPAPAPEPAALPSPCLSRLPKPLEGLGLEDPRTRRPGTTEVGPTSHAPRVWFVLDALGLACATATWLLVLSEGVVLLCAWLLPARRPAYSLAHGSLFHLLAFLALASHARTMLTDPGALPAGALAQPGPTPSGPCCPLCGAIQPPGAHHCSVCGRCIRRRDHHCPWVNNCVGEDNRKFFLLFTLYTALAALHVLLLLGVPALRAHALGQWNLRTTVEPQGSLIYLFLVALNGFVFAAVMFTIQIHAILTDRPGIQPPQRQSGAPGRASPWKNLQAVLGHRVSLAWISPFASPDPQAASEPPNIV", "length": 338, "header": "tr|A0A5G2R2A0-1|A0A5G2R2A0_PIG Isoform 1 of Palmitoyltransferase OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R2A0-1" }, "locus": { "chromosome": "5", "start_pos": 863487, "end_pos": 861647, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067565.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067565.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071229.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071229.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 164, "start_aa": "Thr", "end_pos": 164, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr164", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 78, "start_aa": "Thr", "end_pos": 78, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr78", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0" } ], "pmid": "" }, { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2A0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2A0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 338, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2A0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2A0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2A0" }, { "id": "PF01529", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Palmitoyltransferase DHHC", "eco_id": "ECO_0000259", "start_pos": 169, "end_pos": 284, "start_aa": "Cys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 78, 164 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2D6-1", "uniprot_ac": "A0A5G2R2D6", "uniprot_id": "A0A5G2R2D6_PIG", "mass": { "chemical_mass": 113255.0, "monoisotopic_mass": 113255.0 }, "refseq": {}, "gene_names": [ { "name": "CNTN4", "type": "recommended", "evidence": [ { "id": "A0A5G2R2D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ] } ], "protein_names": [ { "name": "Contactin 4", "type": "synonym", "evidence": [ { "id": "A0A5G2R2D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CNTN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6", "locus": { "chromosome": "13", "start_pos": 59642130, "end_pos": 58974198, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011527", "url": "https://www.ensembl.org/id/ENSSSCG00000011527" } ] } } ], "crossref": [ { "id": "A0A5G2R2D6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2D6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011527", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011527", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04969", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04969", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05853", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05853", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SFM0", "url": "https://www.uniprot.org/uniprotkb/F1SFM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SFM0-1", "url": "https://www.uniprot.org/uniprotkb/F1SFM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLPWELLVLQSFMLCLADDYTLHGPIFIQEPSHVMFPLDSEEKKVKLSCEVKGNPKPHIRWKLNGTDVDIGMDFRYSVVEGSLLINNPNKTQDAGTYQCIATNSFGTIVSREAKLQFAYLENFKTRTRSTVSVRQGQGMVLLCGPPAHSGELNYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNQKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGTTVKLECFALGNPVPTIIWRRADGKPMARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAIEENIFWECKANGRPKPTYRWLKNGDPLLSRDRIHIEQGTLNITIVNLSDAGMYQCVAENKHGVIFSSAELSVIAVGPDFSRTLVKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDVLRENERITISEDGSLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLAIVFTWSFNGHLIDFDKDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDKLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVNTVPEIIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVRPFSPFEVKVGVYNNKGEGPFSPTTVVYSAEEEPSKPPASIFARSLSATDIEVFWASPMEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKTNLKGSALYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGAGPSTSNACALSAISTIMISLTARSSL", "length": 1024, "header": "tr|A0A5G2R2D6-1|A0A5G2R2D6_PIG Isoform 1 of Contactin 4 OS=Sus scrofa OX=9823 GN=CNTN4 PE=1 SV=1 CANONICAL=A0A5G2R2D6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6/entry#A0A5G2R2D6-1", "sequence": { "sequence": "MRLPWELLVLQSFMLCLADDYTLHGPIFIQEPSHVMFPLDSEEKKVKLSCEVKGNPKPHIRWKLNGTDVDIGMDFRYSVVEGSLLINNPNKTQDAGTYQCIATNSFGTIVSREAKLQFAYLENFKTRTRSTVSVRQGQGMVLLCGPPAHSGELNYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNQKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGTTVKLECFALGNPVPTIIWRRADGKPMARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAIEENIFWECKANGRPKPTYRWLKNGDPLLSRDRIHIEQGTLNITIVNLSDAGMYQCVAENKHGVIFSSAELSVIAVGPDFSRTLVKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDVLRENERITISEDGSLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLAIVFTWSFNGHLIDFDKDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDKLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVNTVPEIIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVRPFSPFEVKVGVYNNKGEGPFSPTTVVYSAEEEPSKPPASIFARSLSATDIEVFWASPMEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKTNLKGSALYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGAGPSTSNACALSAISTIMISLTARSSL", "length": 1024, "header": "tr|A0A5G2R2D6-1|A0A5G2R2D6_PIG Isoform 1 of Contactin 4 OS=Sus scrofa OX=9823 GN=CNTN4 PE=1 SV=1 CANONICAL=A0A5G2R2D6-1" }, "locus": { "chromosome": "13", "start_pos": 59639573, "end_pos": 59153014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086762.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086762.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068362.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068362.1" } ] } }, { "isoform_ac": "F1SFM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6/entry#F1SFM0-1", "sequence": { "sequence": "QFCVWKLLVKRNDYTLHGPIFIQEPSHVMFPLDSEEKKVKLSCEVKGNPKPHIRWKLNGTDVDIGMDFRYSVVEGSLLINNPNKTQDAGTYQCIATNSFGTIVSREAKLQFAYLENFKTRTRSTVSVRQGQGMVLLCGPPAHSGELNYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNQKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGTTVKLECFALGNPVPTIIWRRADGKPMARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAIEENIFWECKANGRPKPTYRWLKNGDPLLSRDRIHIEQGTLNITIVNLSDAGMYQCVAENKHGVIFSSAELSVIAVGPDFSRTLVKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDVLRENERITISEDGSLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLAIVFTWSFNGHLIDFDKDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDKLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVNTVPEIIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVRPFSPFEVKVGVYNNKGEGPFSPTTVVYSAEEEPSKPPASIFARSLSATDIEVFWASPMEKNRGRIQGYEVKYWRHEDKEENARKIRTAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGAGPSTSNACALSAISTIMISLTARSSL", "length": 992, "header": "tr|F1SFM0-1|A0A5G2R2D6_PIG Computationally mapped isoform of Contactin 4 OS=Sus scrofa OX=9823 GN=CNTN4 PE=1 SV=4 CANONICAL=A0A5G2R2D6-1" }, "locus": { "chromosome": "13", "start_pos": 59639573, "end_pos": 59310423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012616.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012616.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012286.4", "url": "https://www.ensembl.org/id/ENSSSCP00000012286.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SFM0", "url": "https://www.uniprot.org/uniprotkb/F1SFM0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of neuron differentiation", "id": "GO:0045665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045665", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ], "pmid": "" }, { "name": "dendrite self-avoidance", "id": "GO:0070593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070593", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 705, "end_pos": 707, "annotation": "n_glycosylation_sequon" }, { "start_pos": 763, "end_pos": 765, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" }, { "start_pos": 891, "end_pos": 893, "annotation": "n_glycosylation_sequon" }, { "start_pos": 909, "end_pos": 911, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" }, { "start_pos": 927, "end_pos": 929, "annotation": "n_glycosylation_sequon" }, { "start_pos": 952, "end_pos": 954, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2D6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1024, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2D6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2D6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 599, "end_pos": 697, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R2D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2D6" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 117, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 623, "end_pos": 625 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 705, "end_pos": 707 }, { "start_pos": 763, "end_pos": 765 }, { "start_pos": 857, "end_pos": 859 }, { "start_pos": 891, "end_pos": 893 }, { "start_pos": 909, "end_pos": 911 }, { "start_pos": 90, "end_pos": 92 }, { "start_pos": 927, "end_pos": 929 }, { "start_pos": 952, "end_pos": 954 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2E8-1", "uniprot_ac": "A0A5G2R2E8", "uniprot_id": "A0A5G2R2E8_PIG", "mass": { "chemical_mass": 34684.0, "monoisotopic_mass": 34684.0 }, "refseq": { "ac": "XP_003355697", "name": "olfactory receptor 8S1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355697" }, "gene_names": [ { "name": "LOC100622582", "type": "recommended", "evidence": [ { "id": "A0A5G2R2E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8" } ] }, { "name": "LOC100622582", "type": "synonym", "evidence": [ { "id": "XP_003355697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355697" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R2E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8S1-like", "type": "synonym", "evidence": [ { "id": "XP_003355697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355697" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2E8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2E8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100622582", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8", "locus": {} } ], "crossref": [ { "id": "A0A5G2R2E8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2E8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15229", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15229", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100622582", "url": "https://www.ncbi.nlm.nih.gov/gene/100622582", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100622582", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622582", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMSSQFC", "url": "https://omabrowser.org/oma/group/VMSSQFC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R2E8", "url": "https://www.orthodb.org/?gene=A0A5G2R2E8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003355697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355697", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R2E8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALRNHSSITEFILIGLSNDPHVETLLFVLFLGIYLLTIIGNLTMLLVIRADSSLHTPMYFFLSNLSFLDLCFSSVTVPKLLEDLLSEEKTISVEGCLTQVFFVFITAGTEAFLLSVMAYDRYAAICHPLLYGQVMSIQLCVRLVLISWGLASVNASVIVLLAINLDFCDAQTIHHYTCELPSLFPLSCSDISINIDILICLILLHGLGTFLPVFFSYVRIVSTILSISSTTGRSKAFSTCSSHLIAVILFFGSGLVRYLMPTSGSPLDLLSSLQYSAVTPMLNPLIYSLKNMEVKAAVKRTWEKYLQYFRL", "length": 312, "header": "tr|A0A5G2R2E8-1|A0A5G2R2E8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100622582 PE=3 SV=1 CANONICAL=A0A5G2R2E8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8/entry#A0A5G2R2E8-1", "sequence": { "sequence": "MALRNHSSITEFILIGLSNDPHVETLLFVLFLGIYLLTIIGNLTMLLVIRADSSLHTPMYFFLSNLSFLDLCFSSVTVPKLLEDLLSEEKTISVEGCLTQVFFVFITAGTEAFLLSVMAYDRYAAICHPLLYGQVMSIQLCVRLVLISWGLASVNASVIVLLAINLDFCDAQTIHHYTCELPSLFPLSCSDISINIDILICLILLHGLGTFLPVFFSYVRIVSTILSISSTTGRSKAFSTCSSHLIAVILFFGSGLVRYLMPTSGSPLDLLSSLQYSAVTPMLNPLIYSLKNMEVKAAVKRTWEKYLQYFRL", "length": 312, "header": "tr|A0A5G2R2E8-1|A0A5G2R2E8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100622582 PE=3 SV=1 CANONICAL=A0A5G2R2E8-1" }, "locus": { "chromosome": "5", "start_pos": 79148005, "end_pos": 79147070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089778.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089778.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064708.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064708.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 280, "start_aa": "Thr", "end_pos": 280, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr280", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2E8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100622582", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622582", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BEY3-1", "protein_name": "Olfactory receptor", "gene_name": "OR8S8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALRNHSTITEFILTGLSDDPHIQALLFVLFLVIYLLTVMGNLTMLLVIRADSHLHTPMYFFLSNLSFLDLCFSSVTVPKLLKDLLSEKKTISVEGCLTQVFFVFITAGTEAFLLSMMAYDRYAAICHPLLYGQLMSTQLCVKLILASWGLASLNSVIIVLLAVNLDFCEAQTIHHYTCELPSLFPLSCSDVSVNIDILICSILLHGLGTFLPVVFSYARIVSTILSISSTTGRSKAFSTCSSHLIAVILFFGSGLIRYLMPSSGSSLDLLSSLQYSAVTPMLNPLIYSLKNMEVKAAVKRTLGKYLQYFK", "length": 311 }, "evidence": [ { "id": "A0A5G2R2E8", "url": "https://omabrowser.org/oma/group/A0A5G2R2E8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3IJ10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763846", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAWRNHSAITEFILTGLSDDPLIQALLFVLFLGIYLLTMTGNLMMLLVIRADSHLHTPMYFFLSNLSFLDLCFSSVTIPKLLKDLLSEKKSISIEGCLAQVFFIFITAGTEAFLLSMMAYDRYAAVCHPLLYGQIMSNELCRKLVLLSWGLASLSSLVIVLLAVNLDFCEATTIHHYMCELPSLFPLSCSDISINVDILICSTLLHGLGTFLPIFFSYARIVSTILSVKSTTGRSKAFNTCSSHLIAVVLFFGSGLVRYLMPTSGSSLDLLSSLQYSAVTPMLNPLIYSLKNKEVKAAVKRTLGKCLLYLE", "length": 311 }, "evidence": [ { "id": "A0A5G2R2E8", "url": "https://omabrowser.org/oma/group/A0A5G2R2E8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5USB8-1", "protein_name": "Olfactory receptor", "gene_name": "Or8s8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARSNHSGITEFVLTGLSDDPLIQALLFALFLGIYILTMTGNLMMLVVIRADSHLHTPMYYFLSNLSFLDLCFSSVTVPKLLKDLLSAKKSISVEGCLAQVFFVFITAGTEAFLLSMMAYDRYAAVCHPLLYGQMMSNELCLKLVLLSWGLASLSSVVIVLLAVNLDFCEAYTIHHYTCELPSLFPLSCSDISINVDVLICSTLLHGLGTFLPIFFSYARIVSTVLSMKSTTGRSKAFNTCSSHLIAVVLFFGSGLVRYLMPTSGSSLDLLSSLQYSAVTPMLNPLIYSLKNQEVKTAVKRTLGKCLRYLE", "length": 311 }, "evidence": [ { "id": "A0A5G2R2E8", "url": "https://omabrowser.org/oma/group/A0A5G2R2E8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VET6-1", "protein_name": "Olfactory receptor", "gene_name": "Or8s8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWSNHSVITEFVLTGLSDDPLIQALLFALFLGIYVLTMTGNLTMLLVITADSHLHTPMYFFLSNLSFLDLCFSSVTVPKLLKDLLSAKKTISVEGCLAQVFFVFITAGTEAFLLSMMAYDRYAAVCHPLLYGQMMSNELCLKLVLLSWGLASLSSVVIVLLAVNLDFCEAYTIHHYTCELPSLFPLSCSDISINVDILICSTLLHGLGTFLPIFFSYARIVSTVLSMESTTGRSKAFNTCSSHLIAVVLFFGSGLIRYLMPTSGSSLDLLSSLQYSAVTPMLNPLIYSLKNQEVKAAVRRTLGKCLRYLE", "length": 311 }, "evidence": [ { "id": "A0A5G2R2E8", "url": "https://omabrowser.org/oma/group/A0A5G2R2E8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2E8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2E8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2E8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2E8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2E8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2E8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2E8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2E8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 280 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2G2-1", "uniprot_ac": "A0A5G2R2G2", "uniprot_id": "A0A5G2R2G2_PIG", "mass": { "chemical_mass": 37121.0, "monoisotopic_mass": 37121.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R2G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2G2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2G2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2G2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2", "locus": {} } ], "crossref": [ { "id": "A0A5G2R2G2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2G2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R2G2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VYGSSPSPDHEDGSSHNSTQFHPSSFILLGIPGLEHVHLWIGFPFCAVYLIALLGNVAILFVIQAEPGLHQPMFYFLAMLACTDLSLSTATIPKMLGIFWFNSREILFGACLAQMFVVHLCTGLESGILTVMAVDRYVAIGNPLRYTAILTNKAVAILGAVTIVRSFLFVIPFVFLLLLLSFCGARIIPHTYCEHMGIARLSCASIRANHVFGMVAFSVGFVDLVIIGFSYGKILRTVLHLPSWKARSKALHTCGSHLCVMLIFYVPAFFSFLTHRFGHSIPGYLHIFLANLYMVAPPALNPIIYGVRTKQIRMQVLRILNPKDLMLSRPNHADI", "length": 335, "header": "tr|A0A5G2R2G2-1|A0A5G2R2G2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R2G2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2/entry#A0A5G2R2G2-1", "sequence": { "sequence": "VYGSSPSPDHEDGSSHNSTQFHPSSFILLGIPGLEHVHLWIGFPFCAVYLIALLGNVAILFVIQAEPGLHQPMFYFLAMLACTDLSLSTATIPKMLGIFWFNSREILFGACLAQMFVVHLCTGLESGILTVMAVDRYVAIGNPLRYTAILTNKAVAILGAVTIVRSFLFVIPFVFLLLLLSFCGARIIPHTYCEHMGIARLSCASIRANHVFGMVAFSVGFVDLVIIGFSYGKILRTVLHLPSWKARSKALHTCGSHLCVMLIFYVPAFFSFLTHRFGHSIPGYLHIFLANLYMVAPPALNPIIYGVRTKQIRMQVLRILNPKDLMLSRPNHADI", "length": 335, "header": "tr|A0A5G2R2G2-1|A0A5G2R2G2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R2G2-1" }, "locus": { "chromosome": "9", "start_pos": 3825428, "end_pos": 3823931, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072553.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072553.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068387.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068387.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2G2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2G2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2G2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2G2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2G2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 335, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2G2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2G2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2G2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 305, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 17, "end_pos": 19 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R360-1", "uniprot_ac": "A0A5G2R360", "uniprot_id": "A0A5G2R360_PIG", "mass": { "chemical_mass": 19045.0, "monoisotopic_mass": 19045.0 }, "refseq": {}, "gene_names": [ { "name": "RNASE4", "type": "recommended", "evidence": [ { "id": "A0A5G2R360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360" } ] } ], "protein_names": [ { "name": "Ribonuclease 4", "type": "recommended", "evidence": [ { "id": "A0A5G2R360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cleaves preferentially after uridine bases. Has antimicrobial activity against uropathogenic E.coli (UPEC). Probably contributes to urinary tract sterility.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I5#function" }, { "database": "UniProtKB", "id": "ARBA00045536", "url": "https://www.uniprot.org/uniprotkb/ARBA00045536#function" }, { "database": "UniProtKB", "id": "A0A5G2R360", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R360", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RNASE4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360", "locus": { "chromosome": "7", "start_pos": 78243691, "end_pos": 78244930, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031538", "url": "https://www.ensembl.org/id/ENSSSCG00000031538" } ] } } ], "crossref": [ { "id": "ENSSSCG00000031538", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031538", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06265", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06265", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023411", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023411", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11437", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11437", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11437:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11437:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00074", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00074", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R2I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R360", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R360-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALQRTHVLLLLLLLTLLGLGLVQPSYGQDRMYQRFLRQHVDPDATGGNDAYCNLMMQRRKMTSHYCKRFNTFIHEDIWNIRSICSTSNIQCKNGQMNCHEGVVKVTDCRRQEVPGLPTADTGPWPALDGLSLPVRVIQRCLCTLTNRCSPAGVMAQQLAFNLLLKQQ", "length": 168, "header": "tr|A0A5G2R360-1|A0A5G2R360_PIG Isoform 1 of Ribonuclease 4 OS=Sus scrofa OX=9823 GN=RNASE4 PE=3 SV=1 CANONICAL=A0A5G2R360-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360/entry#A0A5G2R2I5-1", "sequence": { "sequence": "MALQRTHVLLLLLLLTLLGLGLVQPSYGQDRMYQRFLRQHVDPDATGGNDAYCNLMMQRRKMTSHYCKRFNTFIHEDIWNIRSICSTSNIQCKNGQMNCHEGVVKVTDCRRQEVPGLPTADTGPWPALDGLSLPVRVIQRCLCTLTNSCPRLCLLCFFYI", "length": 160, "header": "tr|A0A5G2R2I5-1|A0A5G2R360_PIG Computationally mapped isoform of Ribonuclease 4 OS=Sus scrofa OX=9823 GN=RNASE4 PE=3 SV=1 CANONICAL=A0A5G2R360-1" }, "locus": { "chromosome": "7", "start_pos": 78244913, "end_pos": 78244356, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078860.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078860.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071309.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071309.1" } ] } }, { "isoform_ac": "A0A5G2R360-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360/entry#A0A5G2R360-1", "sequence": { "sequence": "MALQRTHVLLLLLLLTLLGLGLVQPSYGQDRMYQRFLRQHVDPDATGGNDAYCNLMMQRRKMTSHYCKRFNTFIHEDIWNIRSICSTSNIQCKNGQMNCHEGVVKVTDCRRQEVPGLPTADTGPWPALDGLSLPVRVIQRCLCTLTNRCSPAGVMAQQLAFNLLLKQQ", "length": 168, "header": "tr|A0A5G2R360-1|A0A5G2R360_PIG Isoform 1 of Ribonuclease 4 OS=Sus scrofa OX=9823 GN=RNASE4 PE=3 SV=1 CANONICAL=A0A5G2R360-1" }, "locus": { "chromosome": "7", "start_pos": 78244913, "end_pos": 78244410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044269.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044269.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068285.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068285.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2I5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R360", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R360", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R360", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R360", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R360", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360" } ], "pmid": "" }, { "name": "RNA nuclease activity", "id": "GO:0004540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004540", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R360", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R360", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360" } ], "pmid": "" }, { "name": "antibacterial humoral response", "id": "GO:0019731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019731", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R360", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R360", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R360" }, { "id": "SM00092", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00092" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribonuclease A-domain", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 132, "start_aa": "Gln", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2J2-1", "uniprot_ac": "A0A5G2R2J2", "uniprot_id": "A0A5G2R2J2_PIG", "mass": { "chemical_mass": 36163.0, "monoisotopic_mass": 36163.0 }, "refseq": { "ac": "XP_003124267", "name": "olfactory receptor 2T29-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124267" }, "gene_names": [ { "name": "LOC100515886", "type": "recommended", "evidence": [ { "id": "A0A5G2R2J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2" } ] }, { "name": "LOC100515886", "type": "synonym", "evidence": [ { "id": "XP_003124267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124267" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R2J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2T29-like", "type": "synonym", "evidence": [ { "id": "XP_003124267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124267" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100515886", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2", "locus": {} } ], "crossref": [ { "id": "A0A5G2R2J2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2J2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515886", "url": "https://www.ncbi.nlm.nih.gov/gene/100515886", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515886", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515886", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NISAPKC", "url": "https://omabrowser.org/oma/group/NISAPKC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R2J2", "url": "https://www.orthodb.org/?gene=A0A5G2R2J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003124267", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124267", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R2J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNSTSMANHTGQMYFILVGFFLQSKHPAILCAVIFVIFLMALSGNSILILLIHSTAHLHTPMYFFISQLSLMDVMYISVTVPKMLMDQVMGMNKISAPECGMQMFLYLTLGGSEFFLLAAMAYDHYVAICHPLHYSILMNHKVCLLLVSGCWFLGSVDGFMLTPVTMTFPFCRSREIHHFFCEAPVVMKLSCSDTSLYETLMYICCVLMILIPVTVISSSYSFILLTIHRMNSAEGRKKAFTTCSSHMTIVILFYGAAVYTYMLPSSYHTPEKDMVVSVFYTILTPVLNPLIYSLRNKDVTVALRKMLNGEDVFQKTVK", "length": 320, "header": "tr|A0A5G2R2J2-1|A0A5G2R2J2_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100515886 PE=3 SV=1 CANONICAL=A0A5G2R2J2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2/entry#A0A5G2R2J2-1", "sequence": { "sequence": "MDNSTSMANHTGQMYFILVGFFLQSKHPAILCAVIFVIFLMALSGNSILILLIHSTAHLHTPMYFFISQLSLMDVMYISVTVPKMLMDQVMGMNKISAPECGMQMFLYLTLGGSEFFLLAAMAYDHYVAICHPLHYSILMNHKVCLLLVSGCWFLGSVDGFMLTPVTMTFPFCRSREIHHFFCEAPVVMKLSCSDTSLYETLMYICCVLMILIPVTVISSSYSFILLTIHRMNSAEGRKKAFTTCSSHMTIVILFYGAAVYTYMLPSSYHTPEKDMVVSVFYTILTPVLNPLIYSLRNKDVTVALRKMLNGEDVFQKTVK", "length": 320, "header": "tr|A0A5G2R2J2-1|A0A5G2R2J2_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100515886 PE=3 SV=1 CANONICAL=A0A5G2R2J2-1" }, "locus": { "chromosome": "2", "start_pos": 52883197, "end_pos": 52882238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083478.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083478.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070561.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070561.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515886", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515886", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5NC44-1", "protein_name": "Olfactory receptor family 2 subfamily T member 49", "gene_name": "Or2t49", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLTTWMNNYTTQSDFTLVGFFSQSKHPALLAVVIFVVFLMALSGNALLILLILSDIHIPIHLHIPMYFFISQLSLMDMMYISVTVPKMLMDQVLGSHKISAAACGMQMFLYLTLAGSEYFLLAAMSYDHYVAICHPLQYPVLMNHRVCLLLMSVCWILGSLDGFMFTPVTMTFPFCGSREIHHFFCEVPAVTKLSCSDTWLYETLMYVCCVLMLLIPVTVISGSYTSILLTVLRMNSAEGRKKALATCSSHMTVVTLYYGAAIYTYIFPASLHTPEKDMVVSMFYTILTPLLNPLIYSFRNKNVTEAMKKLLGVSTLFQETVK", "length": 324 }, "evidence": [ { "id": "A0A5G2R2J2", "url": "https://omabrowser.org/oma/group/A0A5G2R2J2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2J2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2J2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2J2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2J2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 294, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2K4-1", "uniprot_ac": "A0A5G2R2K4", "uniprot_id": "A0A5G2R2K4_PIG", "mass": { "chemical_mass": 35121.0, "monoisotopic_mass": 35121.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110259613", "type": "recommended", "evidence": [ { "id": "A0A5G2R2K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R2K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4", "locus": {} } ], "crossref": [ { "id": "A0A5G2R2K4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2K4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MVTYMRP", "url": "https://omabrowser.org/oma/group/MVTYMRP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R2K4", "url": "https://www.orthodb.org/?gene=A0A5G2R2K4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R2K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALMGNQTLISHFILLGLFTHSPLHLLLFSIIMVMFLVALSGNGLMILLINIDSRLHIPMYFFLSWLSLMDLMLISTIVPRMAIDFLLGHGSISFTGCGFQILFFLTLLGDECFLLAFMAYDRYVAISNPLRYSVVMSCRVCWLMVVGSWLFGLVDGLIQAIYTLSFPYCGSQEIDHFFCDIPAVLKLACADTSLYETMIYVCCVLMLLLPFSVISVSYLLILVTVLHMRSAEGRKKAFSTCSSHMAVVSLFYGAAMITYMRPQAYHSSKQDKVVSAFYTMITPMLNPLIYSLRNKEVAGALRKLLARCPCGAG", "length": 314, "header": "tr|A0A5G2R2K4-1|A0A5G2R2K4_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110259613 PE=3 SV=1 CANONICAL=A0A5G2R2K4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4/entry#A0A5G2R2K4-1", "sequence": { "sequence": "MALMGNQTLISHFILLGLFTHSPLHLLLFSIIMVMFLVALSGNGLMILLINIDSRLHIPMYFFLSWLSLMDLMLISTIVPRMAIDFLLGHGSISFTGCGFQILFFLTLLGDECFLLAFMAYDRYVAISNPLRYSVVMSCRVCWLMVVGSWLFGLVDGLIQAIYTLSFPYCGSQEIDHFFCDIPAVLKLACADTSLYETMIYVCCVLMLLLPFSVISVSYLLILVTVLHMRSAEGRKKAFSTCSSHMAVVSLFYGAAMITYMRPQAYHSSKQDKVVSAFYTMITPMLNPLIYSLRNKEVAGALRKLLARCPCGAG", "length": 314, "header": "tr|A0A5G2R2K4-1|A0A5G2R2K4_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110259613 PE=3 SV=1 CANONICAL=A0A5G2R2K4-1" }, "locus": { "chromosome": "2", "start_pos": 57507723, "end_pos": 57506782, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081185.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081185.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071421.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071421.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q8VGD7-1", "protein_name": "Olfactory receptor family 2 subfamily T member 26", "gene_name": "Or2t26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWAGNQTLISHFVLLGLFTHSPLHLFLFSIIMVMFLVALSGNGLMILLILMDSRLHTPMYFFLSWLSLMDLMLISTIVPRMAADFLLGRGSISFAGCGLQILFFLTLLGDECFLLAFMAYDRYVAISNPLRYSVIMSRRVCWLMVAGSWLFGLVDGLIQAVFTLRFPYCGSQEIDHFFCEVPAVLKLACADTSLYETMIYVCCVLMLLLPFSVISASYLRILVAVLRMRSAEGRRKAFATCSSHMIVVSLFYGAAMITYMRPQAYHSSKQDKVVSAFYTMITPMLNPLIYSLRNKEVTGALRKLLGKCPCGGGTLG", "length": 317 }, "evidence": [ { "id": "A0A5G2R2K4", "url": "https://omabrowser.org/oma/group/A0A5G2R2K4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2K4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2K4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2K4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2K4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2K6-1", "uniprot_ac": "A0A5G2R2K6", "uniprot_id": "A0A5G2R2K6_PIG", "mass": { "chemical_mass": 44820.0, "monoisotopic_mass": 44820.0 }, "refseq": { "ac": "XP_020936541", "name": "heat shock transcription factor, Y-linked-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936541" }, "gene_names": [ { "name": "LOC110257882", "type": "synonym", "evidence": [ { "id": "XP_020936541", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936541" } ] } ], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R2K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K6/entry#names_and_taxonomy" } ] }, { "name": "heat shock transcription factor, Y-linked-like", "type": "synonym", "evidence": [ { "id": "XP_020936541", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936541" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2K6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K6", "locus": {} } ], "crossref": [ { "id": "A0A5G2R2K6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2K6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045651", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045651", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110257882", "url": "https://www.ncbi.nlm.nih.gov/gene/110257882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110257882", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257882", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R2K6", "url": "https://www.orthodb.org/?gene=A0A5G2R2K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020936541", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936541", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R2K6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQAPSEIQGVSPKDAPTGSESSITSPWCENSIIGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLSLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGNVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPLSNPQPAAHPWFPMPVATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2R2K6-1|A0A5G2R2K6_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R2K6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K6/entry#A0A5G2R2K6-1", "sequence": { "sequence": "MAQAPSEIQGVSPKDAPTGSESSITSPWCENSIIGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLSLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGNVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPLSNPQPAAHPWFPMPVATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2R2K6-1|A0A5G2R2K6_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R2K6-1" }, "locus": { "chromosome": "Y", "start_pos": 23899363, "end_pos": 23897735, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093741.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093741.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076164.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076164.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 356, "start_aa": "Thr", "end_pos": 356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr356", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "ssc:110257882", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257882", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2K6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2K6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2K6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2K6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2K6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2K6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2K6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2K6" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 356 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2R2P2-1", "uniprot_ac": "A0A5G2R2P2", "uniprot_id": "A0A5G2R2P2_PIG", "mass": { "chemical_mass": 15207.0, "monoisotopic_mass": 15207.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "H2B clustered histone 16", "type": "synonym", "evidence": [ { "id": "A0A5G2R2P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2", "locus": {} } ], "crossref": [ { "id": "A0A5G2R2P2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2P2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041356", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041356", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22910", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22910", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000558", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00125", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAARPRGWRITTSARPSRPGRSRRPCGCCCPGSWPSMPCPRAPRLSPSTQAPRAAKLWVLDDQL", "length": 137, "header": "tr|A0A5G2R2P2-1|A0A5G2R2P2_PIG Isoform 1 of H2B clustered histone 16 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R2P2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2/entry#A0A5G2R2P2-1", "sequence": { "sequence": "MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAARPRGWRITTSARPSRPGRSRRPCGCCCPGSWPSMPCPRAPRLSPSTQAPRAAKLWVLDDQL", "length": 137, "header": "tr|A0A5G2R2P2-1|A0A5G2R2P2_PIG Isoform 1 of H2B clustered histone 16 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R2P2-1" }, "locus": { "chromosome": "7", "start_pos": 21620630, "end_pos": 21616792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069351.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069351.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071364.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071364.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "antibacterial humoral response", "id": "GO:0019731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019731", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" } ], "pmid": "" }, { "name": "antimicrobial humoral immune response mediated by antimicrobial peptide", "id": "GO:0061844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061844", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" } ], "pmid": "" }, { "name": "innate immune response in mucosa", "id": "GO:0002227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002227", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2P2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 137, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2P2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2P2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P2" }, { "id": "PF00125", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Core Histone H2A/H2B/H3", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 76, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2R3-1", "uniprot_ac": "A0A5G2R2R3", "uniprot_id": "A0A5G2R2R3_PIG", "mass": { "chemical_mass": 35096.0, "monoisotopic_mass": 35096.0 }, "refseq": { "ac": "XP_001926789", "name": "olfactory receptor 1J4-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926789" }, "gene_names": [ { "name": "LOC100157267", "type": "recommended", "evidence": [ { "id": "A0A5G2R2R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3" } ] }, { "name": "LOC100157267", "type": "synonym", "evidence": [ { "id": "XP_001926789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926789" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R2R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1J4-like", "type": "synonym", "evidence": [ { "id": "XP_001926789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926789" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2R3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2R3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100157267", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3", "locus": {} } ], "crossref": [ { "id": "A0A5G2R2R3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2R3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157267", "url": "https://www.ncbi.nlm.nih.gov/gene/100157267", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157267", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157267", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TACITQI", "url": "https://omabrowser.org/oma/group/TACITQI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R2R3", "url": "https://www.orthodb.org/?gene=A0A5G2R2R3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001926789", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926789", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R2R3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRWENQSSVSEFLLLGLPIQTEQQGVFFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYIFLSHLALTDVSFSSVTVPKMLMNIQTQNQSIPYAGCVTQMYFFIFFCCIDNLLLAMMAYDRYVAICHPLHYTIIMREELCMCLLAGSWLFSCAYALTHTILLAQLSFCDDNIILQFFCDLAALLKLSCSDSSINELIIFSAGAAVVIFSLSCILLSYGQIVVSIRRVPSTKGICKALSTCGSHLSVVCLFYGTSTAVYFFSSSGQSHDEDIISSVMYTVVTPMLNPFIYSLRNRDMKLALGSIFRNNNLFVN", "length": 313, "header": "tr|A0A5G2R2R3-1|A0A5G2R2R3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100157267 PE=3 SV=1 CANONICAL=A0A5G2R2R3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3/entry#A0A5G2R2R3-1", "sequence": { "sequence": "MRWENQSSVSEFLLLGLPIQTEQQGVFFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYIFLSHLALTDVSFSSVTVPKMLMNIQTQNQSIPYAGCVTQMYFFIFFCCIDNLLLAMMAYDRYVAICHPLHYTIIMREELCMCLLAGSWLFSCAYALTHTILLAQLSFCDDNIILQFFCDLAALLKLSCSDSSINELIIFSAGAAVVIFSLSCILLSYGQIVVSIRRVPSTKGICKALSTCGSHLSVVCLFYGTSTAVYFFSSSGQSHDEDIISSVMYTVVTPMLNPFIYSLRNRDMKLALGSIFRNNNLFVN", "length": 313, "header": "tr|A0A5G2R2R3-1|A0A5G2R2R3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100157267 PE=3 SV=1 CANONICAL=A0A5G2R2R3-1" }, "locus": { "chromosome": "AEMK02000598.1", "start_pos": 902299, "end_pos": 901361, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069561.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069561.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064834.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064834.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2R3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157267", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157267", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2R3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2R3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2R3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2R3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2R3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2R3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2R3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2R3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2W0-1", "uniprot_ac": "A0A5G2R2W0", "uniprot_id": "A0A5G2R2W0_PIG", "mass": { "chemical_mass": 33167.0, "monoisotopic_mass": 33167.0 }, "refseq": { "ac": "XP_020941879", "name": "paired immunoglobulin-like type 2 receptor alpha isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941879" }, "gene_names": [ { "name": "PILRA", "type": "recommended", "evidence": [ { "id": "A0A5G2R2W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2W0" } ] }, { "name": "PILRA", "type": "synonym", "evidence": [ { "id": "XP_020941879", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941879" } ] } ], "protein_names": [ { "name": "Paired immunoglobin like type 2 receptor alpha", "type": "synonym", "evidence": [ { "id": "A0A5G2R2W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2W0/entry#names_and_taxonomy" } ] }, { "name": "paired immunoglobulin-like type 2 receptor alpha isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020941879", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941879" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2W0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PILRA", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2W0", "locus": {} } ], "crossref": [ { "id": "A0A5G2R2W0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2W0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026653", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026653", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100515653", "url": "https://www.ncbi.nlm.nih.gov/gene/100515653", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KQMWQSI", "url": "https://omabrowser.org/oma/group/KQMWQSI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR15549", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15549", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15549:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15549:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-198933", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-198933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020941879", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941879", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R2W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2W0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2W0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RA06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RA06-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LG64", "url": "https://www.uniprot.org/uniprotkb/I3LG64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LG64-1", "url": "https://www.uniprot.org/uniprotkb/I3LG64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELPLLLPLLLPLLLLLPPASLQGDHWAQPKARFHSGMNQQKQLSAPEGGSIRIPFSFDYPWDSGRVSNVKISWRWKHFHGDFIYNITPPFIHNNFKNRLLLNWEEGMKKGSLQISNLRREDEGSYFCRVEMITEKYGEQKWQSIQGTELTITHTQTTTLGSTTTAATTTATTAGLGTSENQRHSGSWPLSTEATVGIAGAVLVIAIVGLILCLWWKKRKGLQTKARTPARGSFQNLEEKYENIGNKVQQTNPKLDQNNDGILYASLTLHNLPSPAAPPCPPAHGGPQEETVYSALKT", "length": 298, "header": "tr|A0A5G2R2W0-1|A0A5G2R2W0_PIG Isoform 1 of Paired immunoglobin like type 2 receptor alpha OS=Sus scrofa OX=9823 GN=PILRA PE=4 SV=2 CANONICAL=A0A5G2R2W0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2W0/entry#A0A5G2R2W0-1", "sequence": { "sequence": "MELPLLLPLLLPLLLLLPPASLQGDHWAQPKARFHSGMNQQKQLSAPEGGSIRIPFSFDYPWDSGRVSNVKISWRWKHFHGDFIYNITPPFIHNNFKNRLLLNWEEGMKKGSLQISNLRREDEGSYFCRVEMITEKYGEQKWQSIQGTELTITHTQTTTLGSTTTAATTTATTAGLGTSENQRHSGSWPLSTEATVGIAGAVLVIAIVGLILCLWWKKRKGLQTKARTPARGSFQNLEEKYENIGNKVQQTNPKLDQNNDGILYASLTLHNLPSPAAPPCPPAHGGPQEETVYSALKT", "length": 298, "header": "tr|A0A5G2R2W0-1|A0A5G2R2W0_PIG Isoform 1 of Paired immunoglobin like type 2 receptor alpha OS=Sus scrofa OX=9823 GN=PILRA PE=4 SV=2 CANONICAL=A0A5G2R2W0-1" }, "locus": { "chromosome": "3", "start_pos": 8322445, "end_pos": 8305957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076571.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076571.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070677.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070677.2" } ] } }, { "isoform_ac": "A0A5G2RA06-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2W0/entry#A0A5G2RA06-1", "sequence": { "sequence": "MELPLLLPLLLPLLLLLPPASLQGDHWAQPKARFHSGMNQQKQLSAPEGGSIRIPFSFDYPWDSGRVSNVKISWRWKHFHGDFIYNITPPFIHNNFKNRLLLNWEEGMKKGSLQISNLRREDEGSYFCRVEMITEKYGEQKWQSIQGTELTITHKDPSRIWRRNTRTLGTKCNRQTPSWTKIMMASSMPPSPSTTCPHQPHLHALPPTGAPRKRPCTLP", "length": 219, "header": "tr|A0A5G2RA06-1|A0A5G2R2W0_PIG Computationally mapped isoform of Paired immunoglobin like type 2 receptor alpha OS=Sus scrofa OX=9823 GN=PILRA PE=4 SV=1 CANONICAL=A0A5G2R2W0-1" }, "locus": { "chromosome": "3", "start_pos": 8322437, "end_pos": 8305957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071672.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071672.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074139.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074139.1" } ] } }, { "isoform_ac": "I3LG64-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2W0/entry#I3LG64-1", "sequence": { "sequence": "MELPLLLPLLLPLLLLLPPASLQGDHWAQPKARFHSGMNQQKQLSAPEGGSIRIPFSFDYPWDSGRVSNVKISWRWKHFHGDFIYNITPPFIHNNFKNRLLLNWEEGMKKGSLQISNLRREDEGSYFCRVEMITEKYGEQKWQSIQGTELTITHSLQTKARTPARGSFQNLEEKYENIGNKVQQTNPKLDQNNDGILYASLTLHNLPSPAAPPCPPAHGGPQEETVYSALKT", "length": 232, "header": "tr|I3LG64-1|A0A5G2R2W0_PIG Computationally mapped isoform of Paired immunoglobin like type 2 receptor alpha OS=Sus scrofa OX=9823 GN=PILRA PE=4 SV=3 CANONICAL=A0A5G2R2W0-1" }, "locus": { "chromosome": "3", "start_pos": 8322445, "end_pos": 8305957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022696.4", "url": "https://www.ensembl.org/id/ENSSSCT00000022696.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023057.3", "url": "https://www.ensembl.org/id/ENSSSCP00000023057.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 88, "start_aa": "Thr", "end_pos": 88, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr88", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LG64", "url": "https://www.uniprot.org/uniprotkb/I3LG64" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-198933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-198933", "resource": "Reactome", "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ADV0-1", "protein_name": "Paired immunoglobin-like type 2 receptor alpha", "gene_name": "Pilra", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARLLLLLLSAACLHSGNSAGYPKKYDYGVDQPAVLSGVQGSSIEIPFSFYFPWNLTKDPQMSIAWRWKNFHGEFIYNSTQPFIHEHFKDRLIMNWTQGQTSGVLRILNFKKNDQATYFGRVLLQTTEGMKVWQSIPGTNLTVTNNTSTPATLPSTTTATPSTHPQTVTTEGMKDEPKSGLDPQTIIVLAVAAAVFLAGVLGLTVFLGWRRKQGQRTKAETPAREPLENSEKRESIGHEGQYMDPTENPKDNNIVYASISLSSPTSPGAAPSLPVQKNPQEETVYSTIKAK", "length": 291 }, "evidence": [ { "id": "A0A5G2R2W0", "url": "https://omabrowser.org/oma/group/A0A5G2R2W0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MJX3-1", "protein_name": "Paired immunoglobin like type 2 receptor alpha", "gene_name": "PILRA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLPLLLPLLLLPASLQAGHRAQRNSQQHYEMKQPRDLSAPEGGSILIPFSFSHPGELAKVPNMRIFWRWKHFHGEFIYNTSPLFTHKNFKNRLILNWKEPEKNGSLQISNLRREDQSVYFCRVQLDTLRDGKQKWQSIEGTKLTITPPSKTTTQNPTTAATTATAVLKNSEGGKSPWSWLQSTEAIVGLALASAALVATIVALIVYFRCKRSKSVQTEARTPARESFKNTEENYENIGNKGEYVDPKPDAKDDGGGSGGVLYASLALSRLNSPATAVPPLPSLHGGPQEETLYSVLKT", "length": 299 }, "evidence": [ { "id": "A0A5G2R2W0", "url": "https://omabrowser.org/oma/group/A0A5G2R2W0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q2YFS3-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilra", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLISLPGGTPAMAQILLLLSSACLHAGNSERSNRKNGFGVNQPESCSGVQGGSIDIPFSFYFPWKLAKDPQMSIAWRWKDFHGEFIYNSSLPFIHEHFKGRLILNWTQGQTSGVLRILNLKESDQTRYFGRVFLQTTEGIQFWQSIPGTQLNVTNATCTPTTLPSTTAATSAHTQNDITEVKSANIGGLDLQTTVGLATAAAVFLVGVLGLIVFLWWKRRRQGQKTKAEIPAREPLETSEKHESVGHEGQCMDPKENPKDNNIVYASISLSSPTSPGTAPNLPVHGNPQEETVYSIVKAK", "length": 302 }, "evidence": [ { "id": "A0A5G2R2W0", "url": "https://omabrowser.org/oma/group/A0A5G2R2W0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2W0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "MHC class I protein binding", "id": "GO:0042288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042288", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2W0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2W0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 298, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2W0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2W0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2W0" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 146, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 88 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2Y9-1", "uniprot_ac": "A0A5G2R2Y9", "uniprot_id": "A0A5G2R2Y9_PIG", "mass": { "chemical_mass": 36709.0, "monoisotopic_mass": 36709.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM120A", "type": "recommended", "evidence": [ { "id": "A0A5G2R2Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ] } ], "protein_names": [ { "name": "Transmembrane protein 120A", "type": "synonym", "evidence": [ { "id": "A0A5G2R2Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMEM120A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9", "locus": { "chromosome": "3", "start_pos": 10212610, "end_pos": 10206630, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021837", "url": "https://www.ensembl.org/id/ENSSSCG00000021837" } ] } } ], "crossref": [ { "id": "A0A5G2R2Y9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2Y9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000021837", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000021837", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR012926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21433", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21433", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21433:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21433:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07851", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07851", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LEI2", "url": "https://www.uniprot.org/uniprotkb/I3LEI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LEI2-1", "url": "https://www.uniprot.org/uniprotkb/I3LEI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPPPPDPLGDCLRDWEELQQDFQGIQETHRLYRLKLEELIKLQNNCTSSITRQKKRLQELALVLKKCKHSLPSEAEEAAQELESQIKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKVTDAAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRALGERHTMDLTVEGFQSWMWRGLTFLLPFLFFGQFWQLFNALTLFSLARDPECKEWQVLMCGLPFLLLFLGNFFTTLRVVHQKFHNQQHGGKKD", "length": 311, "header": "tr|A0A5G2R2Y9-1|A0A5G2R2Y9_PIG Isoform 1 of Transmembrane protein 120A OS=Sus scrofa OX=9823 GN=TMEM120A PE=1 SV=2 CANONICAL=A0A5G2R2Y9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9/entry#A0A5G2R2Y9-1", "sequence": { "sequence": "MNPPPPDPLGDCLRDWEELQQDFQGIQETHRLYRLKLEELIKLQNNCTSSITRQKKRLQELALVLKKCKHSLPSEAEEAAQELESQIKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKVTDAAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRALGERHTMDLTVEGFQSWMWRGLTFLLPFLFFGQFWQLFNALTLFSLARDPECKEWQVLMCGLPFLLLFLGNFFTTLRVVHQKFHNQQHGGKKD", "length": 311, "header": "tr|A0A5G2R2Y9-1|A0A5G2R2Y9_PIG Isoform 1 of Transmembrane protein 120A OS=Sus scrofa OX=9823 GN=TMEM120A PE=1 SV=2 CANONICAL=A0A5G2R2Y9-1" }, "locus": { "chromosome": "3", "start_pos": 10212382, "end_pos": 10206704, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077962.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077962.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071557.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071557.2" } ] } }, { "isoform_ac": "I3LEI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9/entry#I3LEI2-1", "sequence": { "sequence": "MNPPPPDPLGDCLRDWEELQQDFQGIQETHRLYRLKLEELIKLQNNCTSSITRQKKRLQELALVLKKCKHSLPSEAEEAAQELESQIKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKFAYKAEYEKFKLYLTIILILVSFTCRFLLNSRVTDAAFNFLLVWYYCTLTIRESILINNGSRWVRPRPGHGGDRSDGRFLIQDQRLVGFPPLRVHVPVGSHADMARRPHVPEVPEPVPVLLHVPELCAVPPILLPERLSVPPAGPGREAHHGPDRGGLPVLDVAGPHLPAALPLLWTVLAAF", "length": 308, "header": "tr|I3LEI2-1|A0A5G2R2Y9_PIG Computationally mapped isoform of Transmembrane protein 120A OS=Sus scrofa OX=9823 GN=TMEM120A PE=1 SV=4 CANONICAL=A0A5G2R2Y9-1" }, "locus": { "chromosome": "3", "start_pos": 10212122, "end_pos": 10206704, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026475.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026475.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022470.4", "url": "https://www.ensembl.org/id/ENSSSCP00000022470.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LEI2", "url": "https://www.uniprot.org/uniprotkb/I3LEI2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "coenzyme A binding", "id": "GO:0120225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120225", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ], "pmid": "" }, { "name": "monoatomic ion channel activity", "id": "GO:0005216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005216", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ], "pmid": "" }, { "name": "protein heterooligomerization", "id": "GO:0051291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051291", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of pain", "id": "GO:0050966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050966", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Y9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2Y9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2Y9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2Y9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 153, "end_pos": 155 }, { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R2Z4-1", "uniprot_ac": "A0A5G2R2Z4", "uniprot_id": "A0A5G2R2Z4_PIG", "mass": { "chemical_mass": 124775.0, "monoisotopic_mass": 124775.0 }, "refseq": {}, "gene_names": [ { "name": "ABCB5", "type": "recommended", "evidence": [ { "id": "A0A5G2R2Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ] } ], "protein_names": [ { "name": "ATP-binding cassette sub-family B member 5", "type": "recommended", "evidence": [ { "id": "A0A5G2R2Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4/entry#names_and_taxonomy" } ] }, { "name": "7.6.2.2", "type": "synonym", "evidence": [ { "id": "A0A5G2R2Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4/entry#names_and_taxonomy" } ] }, { "name": "ABCB5 P-gp", "type": "synonym", "evidence": [ { "id": "A0A5G2R2Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4/entry#names_and_taxonomy" } ] }, { "name": "p-glycoprotein ABCB5", "type": "synonym", "evidence": [ { "id": "A0A5G2R2Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4#function" }, { "database": "UniProtKB", "id": "ARBA00059665", "url": "https://www.uniprot.org/uniprotkb/ARBA00059665#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ABCB5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4", "locus": { "chromosome": "9", "start_pos": 89738606, "end_pos": 89632204, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015377", "url": "https://www.ensembl.org/id/ENSSSCG00000015377" } ] } } ], "crossref": [ { "id": "A0A5G2R2Z4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2Z4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015377", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015377", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03249", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03249", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18577", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18577", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18578", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18578", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR43394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43394:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43394:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-382556", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-382556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "33147", "url": "https://www.rhea-db.org/rhea/33147", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R333", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R333", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R333-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R333-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQISFWVMTAARQTKRIRKQFFHSILAQDISWFDSCGIGELNTRMTDDINKINDGIGDKIALLFQNMSTFSIGLVIGLAKGWKLTLVTLSTSPLIIASAAMFSRIVISLSSKELNAYSKAGAVAEEVLSSIRTVIAFGAQEKEIQRYTQNLKDAKDVGIKKAIASKLSLGAVYFFMNGTYGLAFWYGTFLILSGEPDYTIGTVLAVFFSVIHSSYCIGAAAPNFESFAIARGAAFNIFHIIDKKPTIDNFSTTGCKLECIEGTVEFKNVSFSYPSRPSVKILKGLSLKIKSGETVALVGPSGSGKSTAVQLLQRLYDPDDGFITVDGKDIRTLNVQHYREHFGVVSQEPVLFGTTINNNIKYGRDSVTDEDIENAAKEANAYDFIMEFPKKFNTLVGEKGAQMSGGQKQRIAIARALIRNPKILILDEATSALDTESESVVQAALEKASKGRTTIVIAHRLSTIRSADMIVTLKDGMVVEKGTHAELMAKQGPYYSLAISQDIKKADEQMESMAYSTEKNTSSTPLCSMNSINPDTDKSEDSIQYKKTSLPEVSLLKIFKLNKSEWPSVVLGTLASVLNGSVHPVFSIIFAKIVTMFENDDKTTLKHDAEIYSMIFVILGIICFVSYFIQGLFYGRAGEILTMRLRHLAFKAMLYQDISWFDEKENSTGALTTILAIDIAQIQGATGSRVGVLTQNATNMGLSVIISFIYGWEMTLLILSIAPVLALAGMIETAAMTGFANKDKQELERAGKIATEAVENIRTIVSLTREKAFEQMYEETLQTQHRNTLKKAQIIGICYAFSHAFVYFAYAAGFLFGTHLIQAGRMTPEGMFIVFTAVAYGAMAIGETLVLAPEYSRAKSGAAHLFALLEKKPTIDSHSQEGTKTDIFEGNIEFREVSFFYPCRPDVLILRNLSLSIEKGKTVAFVGSSGCGKSTSVQLMQRFYDPVKGQVLFDGVDAKELNVQWLRSQIAIVSQEPVLFNCSIAENIAYGDNSRVVPLHEIKEVADAANIHSFIEGLPEKYNTQVGPKGTQLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKVVQHALDKASKGRTCLMVAHRLSTIQNADLIVVLHNGKIKEQGTHQELLKNRDIYFKLVNAQSVQ", "length": 1134, "header": "tr|A0A5G2R2Z4-1|A0A5G2R2Z4_PIG Isoform 1 of ATP-binding cassette sub-family B member 5 OS=Sus scrofa OX=9823 GN=ABCB5 PE=3 SV=2 CANONICAL=A0A5G2R2Z4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4/entry#A0A5G2R2Z4-1", "sequence": { "sequence": "MQISFWVMTAARQTKRIRKQFFHSILAQDISWFDSCGIGELNTRMTDDINKINDGIGDKIALLFQNMSTFSIGLVIGLAKGWKLTLVTLSTSPLIIASAAMFSRIVISLSSKELNAYSKAGAVAEEVLSSIRTVIAFGAQEKEIQRYTQNLKDAKDVGIKKAIASKLSLGAVYFFMNGTYGLAFWYGTFLILSGEPDYTIGTVLAVFFSVIHSSYCIGAAAPNFESFAIARGAAFNIFHIIDKKPTIDNFSTTGCKLECIEGTVEFKNVSFSYPSRPSVKILKGLSLKIKSGETVALVGPSGSGKSTAVQLLQRLYDPDDGFITVDGKDIRTLNVQHYREHFGVVSQEPVLFGTTINNNIKYGRDSVTDEDIENAAKEANAYDFIMEFPKKFNTLVGEKGAQMSGGQKQRIAIARALIRNPKILILDEATSALDTESESVVQAALEKASKGRTTIVIAHRLSTIRSADMIVTLKDGMVVEKGTHAELMAKQGPYYSLAISQDIKKADEQMESMAYSTEKNTSSTPLCSMNSINPDTDKSEDSIQYKKTSLPEVSLLKIFKLNKSEWPSVVLGTLASVLNGSVHPVFSIIFAKIVTMFENDDKTTLKHDAEIYSMIFVILGIICFVSYFIQGLFYGRAGEILTMRLRHLAFKAMLYQDISWFDEKENSTGALTTILAIDIAQIQGATGSRVGVLTQNATNMGLSVIISFIYGWEMTLLILSIAPVLALAGMIETAAMTGFANKDKQELERAGKIATEAVENIRTIVSLTREKAFEQMYEETLQTQHRNTLKKAQIIGICYAFSHAFVYFAYAAGFLFGTHLIQAGRMTPEGMFIVFTAVAYGAMAIGETLVLAPEYSRAKSGAAHLFALLEKKPTIDSHSQEGTKTDIFEGNIEFREVSFFYPCRPDVLILRNLSLSIEKGKTVAFVGSSGCGKSTSVQLMQRFYDPVKGQVLFDGVDAKELNVQWLRSQIAIVSQEPVLFNCSIAENIAYGDNSRVVPLHEIKEVADAANIHSFIEGLPEKYNTQVGPKGTQLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKVVQHALDKASKGRTCLMVAHRLSTIQNADLIVVLHNGKIKEQGTHQELLKNRDIYFKLVNAQSVQ", "length": 1134, "header": "tr|A0A5G2R2Z4-1|A0A5G2R2Z4_PIG Isoform 1 of ATP-binding cassette sub-family B member 5 OS=Sus scrofa OX=9823 GN=ABCB5 PE=3 SV=2 CANONICAL=A0A5G2R2Z4-1" }, "locus": { "chromosome": "9", "start_pos": 89737645, "end_pos": 89647358, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084938.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084938.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070717.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070717.2" } ] } }, { "isoform_ac": "A0A5G2R333-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4/entry#A0A5G2R333-1", "sequence": { "sequence": "MQISFWVMTAARQTKRIRKQFFHSILAQDISWFDSCGIGELNTRMTDDINKINDGIGDKIALLFQNMSTFSIGLVIGLAKGWKLTLVTLSTSPLIIASAAMFSRIVISLSSKELNAYSKAGAVAEEVLSSIRTVIAFGAQEKEIQRYTQNLKDAKDVGIKKAIASKLSLGAVYFFMNGTYGLAFWYGTFLILSGEPDYTIGTVLAVFFSVIHSSYCIGAAAPNFESFAIARGAAFNIFHIIDKKPTIDNFSTTGCKLECIEGTVEFKNVSFSYPSRPSVKILKGLSLKIKSGETVALVGPSGSGKSTAVQLLQRLYDPDDGFITVDGKDIRTLNVQHYREHFGVVSQEPVLFGTTINNNIKYGRDSVTDEDIENAAKEANAYDFIMEFPKKFNTLVGEKGAQMSGGQKQRIAIARALIRNPKILILDEATSALDTESESVVQAALEKKKW", "length": 450, "header": "tr|A0A5G2R333-1|A0A5G2R2Z4_PIG Computationally mapped isoform of ATP-binding cassette sub-family B member 5 OS=Sus scrofa OX=9823 GN=ABCB5 PE=3 SV=2 CANONICAL=A0A5G2R2Z4-1" }, "locus": { "chromosome": "9", "start_pos": 89669837, "end_pos": 89647358, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083113.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083113.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068607.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068607.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R333", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R333" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-382556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-382556", "resource": "Reactome", "description": "ABC-family protein mediated transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "pmid": "" }, { "name": "efflux transmembrane transporter activity", "id": "GO:0015562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015562", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "pmid": "" }, { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1065, "end_pos": 1067, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 579, "end_pos": 581, "annotation": "n_glycosylation_sequon" }, { "start_pos": 666, "end_pos": 668, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 696, "end_pos": 698, "annotation": "n_glycosylation_sequon" }, { "start_pos": 912, "end_pos": 914, "annotation": "n_glycosylation_sequon" }, { "start_pos": 981, "end_pos": 983, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "33147", "name": "", "equation": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "33147", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33147" } ] }, { "id": "R-SSC-1467457", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1467457", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1467457" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R2Z4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1134, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R2Z4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R2Z4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R2Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" }, { "id": "PS50929", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50929" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transmembrane type-1", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 228, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R2Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Z4" }, { "id": "PS50893", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 264, "end_pos": 500, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1065, "end_pos": 1067 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 520, "end_pos": 522 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 579, "end_pos": 581 }, { "start_pos": 666, "end_pos": 668 }, { "start_pos": 66, "end_pos": 68 }, { "start_pos": 696, "end_pos": 698 }, { "start_pos": 912, "end_pos": 914 }, { "start_pos": 981, "end_pos": 983 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R305-1", "uniprot_ac": "A0A5G2R305", "uniprot_id": "A0A5G2R305_PIG", "mass": { "chemical_mass": 52857.0, "monoisotopic_mass": 52857.0 }, "refseq": { "ac": "XP_001925657", "name": "hyaluronan and proteoglycan link protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925657" }, "gene_names": [ { "name": "HAPLN3", "type": "recommended", "evidence": [ { "id": "A0A5G2R305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" } ] }, { "name": "HAPLN3", "type": "synonym", "evidence": [ { "id": "XP_001925657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925657" } ] } ], "protein_names": [ { "name": "Hyaluronan and proteoglycan link protein 3", "type": "recommended", "evidence": [ { "id": "A0A5G2R305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305/entry#names_and_taxonomy" } ] }, { "name": "hyaluronan and proteoglycan link protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001925657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925657" } ] } ], "function": [ { "annotation": "May function in hyaluronic acid binding.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R305", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305#function" }, { "database": "UniProtKB", "id": "ARBA00059795", "url": "https://www.uniprot.org/uniprotkb/ARBA00059795#function" }, { "database": "UniProtKB", "id": "A0A4X1U6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6Q5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R305", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HAPLN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305", "locus": { "chromosome": "7", "start_pos": 54519800, "end_pos": 54537434, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000030597", "url": "https://www.ensembl.org/id/ENSSSCG00000030597" } ] } } ], "crossref": [ { "id": "A0A5G2R305", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R305", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000030597", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000030597", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03518", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03518", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03519", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03519", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05877", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05877", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157078", "url": "https://www.ncbi.nlm.nih.gov/gene/100157078", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157078", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157078", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHPRPNC", "url": "https://omabrowser.org/oma/group/AHPRPNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U6Q5", "url": "https://www.orthodb.org/?gene=A0A4X1U6Q5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R305", "url": "https://www.orthodb.org/?gene=A0A5G2R305", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22804", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22804", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22804:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22804:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001925657", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925657", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U6Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R305", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R305-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPSLYRGSSSIPPHLLPPDGTAAQGPDPPPFTARPAVPRVGGGPRPSLETARVAPSLQAVQDPQICPLPRTWSACSQEHSRRQEPDAWGRLPQAPASPGMPWHCHMHDTMGLPLLVLLLPLCCVSGLPFYNGFYYSNSLNGRNSGNGHGEGIFNGVKLVVETPEETLFSHRGANVTLPCRYRYEPALVSPRPVRIKWWKLSENGTLEQDVLVAIGLRHRSFGDYQGRVHLRRDREQEVSLEIRDLRLEDYGRYRCEVIDGLEDESGLVELELRGVVFPYQHPRGRYQFNFHEAQRACEEQDAVVASFEQLFRAWEEGLDWCNAGWLQDASVQYPITQTRHPCGGLSLAPGVRSYGPRHRRRHRYDVFCFAAALRGQVYYLEHPEKLTLAEAKEACQEDGAQIAKVGQLFAAWKFRGLDRCDAGWLADGSARYPVAHPRSNCGSVEPGVRSFGFPDPQSRNYGVYCHRPR", "length": 470, "header": "tr|A0A5G2R305-1|A0A5G2R305_PIG Isoform 1 of Hyaluronan and proteoglycan link protein 3 OS=Sus scrofa OX=9823 GN=HAPLN3 PE=1 SV=1 CANONICAL=A0A5G2R305-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U6Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305/entry#A0A4X1U6Q5-1", "sequence": { "sequence": "MPWHCHMHDTMGLPLLVLLLPLCCVSGLPFYNGFYYSNSLNGRNSGNGHGEGIFNGVKLVVETPEETLFSHRGANVTLPCRYRYEPALVSPRPVRIKWWKLSENGTLEQDVLVAIGLRHRSFGDYQGRVHLRRDREQEVSLEIRDLRLEDYGRYRCEVIDGLEDESGLVELELRGVVFPYQHPRGRYQFNFHEAQRACEEQDAVVASFEQLFRAWEEGLDWCNAGWLQDASVQYPITQTRHPCGGLSLAPGVRSYGPRHRRRHRYDVFCFAAALRGQVYYLEHPEKLTLAEAKEACQEDGAQIAKVGQLFAAWKFRGLDRCDAGWLADGSARYPVAHPRSNCGSVEPGVRSFGFPDPQSRNYGVYCHRPR", "length": 370, "header": "tr|A0A4X1U6Q5-1|A0A4X1U6Q5_PIG Computationally mapped isoform of Hyaluronan and proteoglycan link protein 3 OS=Sus scrofa OX=9823 GN=HAPLN3 PE=1 SV=1 CANONICAL=A0A5G2R305-1" }, "locus": { "chromosome": "7", "start_pos": 54529122, "end_pos": 54522474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023723.4", "url": "https://www.ensembl.org/id/ENSSSCT00000023723.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024189.4", "url": "https://www.ensembl.org/id/ENSSSCP00000024189.4" } ] } }, { "isoform_ac": "A0A5G2R305-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305/entry#A0A5G2R305-1", "sequence": { "sequence": "MRPSLYRGSSSIPPHLLPPDGTAAQGPDPPPFTARPAVPRVGGGPRPSLETARVAPSLQAVQDPQICPLPRTWSACSQEHSRRQEPDAWGRLPQAPASPGMPWHCHMHDTMGLPLLVLLLPLCCVSGLPFYNGFYYSNSLNGRNSGNGHGEGIFNGVKLVVETPEETLFSHRGANVTLPCRYRYEPALVSPRPVRIKWWKLSENGTLEQDVLVAIGLRHRSFGDYQGRVHLRRDREQEVSLEIRDLRLEDYGRYRCEVIDGLEDESGLVELELRGVVFPYQHPRGRYQFNFHEAQRACEEQDAVVASFEQLFRAWEEGLDWCNAGWLQDASVQYPITQTRHPCGGLSLAPGVRSYGPRHRRRHRYDVFCFAAALRGQVYYLEHPEKLTLAEAKEACQEDGAQIAKVGQLFAAWKFRGLDRCDAGWLADGSARYPVAHPRSNCGSVEPGVRSFGFPDPQSRNYGVYCHRPR", "length": 470, "header": "tr|A0A5G2R305-1|A0A5G2R305_PIG Isoform 1 of Hyaluronan and proteoglycan link protein 3 OS=Sus scrofa OX=9823 GN=HAPLN3 PE=1 SV=1 CANONICAL=A0A5G2R305-1" }, "locus": { "chromosome": "7", "start_pos": 54537174, "end_pos": 54522474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087928.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087928.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064934.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064934.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R305", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157078", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157078", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZJK1-1", "protein_name": "Hyaluronan and proteoglycan link protein 3", "gene_name": "HAPLN3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLLLPLLLKATLLRMVNSYHPFYNGFYYNHVMNDDDNGNEKVVDFNGVRLVVETSKDPIYSFSGVNVTLPCHYHHEPESEAKHKIRIKWSKLRDDYTKEQDVLVAIGKTYMAFGDFQGRAHLHRAGQREASLLISDVRLQDDGKYRCEVIDGLEDASDVVELRLRGIVFPYQPPRGQYSLNFHEAERVCQEQGSLIATFHQLFQAWSEGLDWCNAGWLADGTVHYPIRLPRKPCGGVHLAPGIRSYGPRHRHLHRFDVFCFSSRLRGEVFYLEHPTRMTLEEAKQACQDAGAEIAKVGHLYSAWKFHGLDRCDAGWLADGSVRYPIAKPRPNCGPTEPGVRSFGFPSKGRFGVFCYKER", "length": 359 }, "evidence": [ { "id": "A0A5G2R305", "url": "https://omabrowser.org/oma/group/A0A5G2R305/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3ICD4-1", "protein_name": "Hyaluronan and proteoglycan link protein 3", "gene_name": "Hapln3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLFLVLLLSLSCVMGLPFSNGFYYSNGLHSRTLGHGYGEGLFNGVKLVVETTEESLFSHRGASVTLPCHYRYEPALASPRHVRVKWWKLSENGSPEQDVLVAIGQRHRSFGNYQGRVQLRQGKQQEVSLELRDLRPEDSGRYRCEVIDGLEDESGLVELELRGVVFPYQPREGRYQLNFHEAQKACQEQDAVVASFEQLFRAWEEGLDWCNAGWLQDASVQYPIALPRQPCGGLGLAPGVRSYGQRHHRLHRYDVFCFTAVLRGWVYYLEHPRKLTLLEAREACQEDGAQISTVGQLFAAWKFRGLDRCDAGWLADGSARYPIVHPRPNCGPPEPGVRTFGFPDPHSRYGVYCYRQR", "length": 359 }, "evidence": [ { "id": "A0A5G2R305", "url": "https://omabrowser.org/oma/group/A0A5G2R305/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q80WM5-1", "protein_name": "Hyaluronan and proteoglycan link protein 3", "gene_name": "Hapln3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLLFLVLLSPFPCVLGLPFYNGFYYSNDLSGRTLGNGYGEGLFNGVKLVVETTEESLFSHQGASVTLPCHYHYEPALASPRHVRVKWWKLSENGAPEQDVLVVIGQRHRSFGDYQGRVQLRQDKQQEVSLELRDLRLEDSGRYRCEVIDGLEDESGLVELELRGVVFPYQSREGRYQLNFHEAQQACQEQGAMVATFEQLFRAWEEGLDWCNAGWLQDASVQYPIVLPRQPCGGLGLAPGVRSYGQRHHRLHRYDVFCFAAALKGRVYYLENPKKLTLLEAREACQEDGAQISTVGQLFAAWKFRGLDRCDAGWLADGSARYPIVHPRLNCGPPEPGVRTFGFPDPHTRYGVYCYVQH", "length": 359 }, "evidence": [ { "id": "A0A5G2R305", "url": "https://omabrowser.org/oma/group/A0A5G2R305/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96S86-1", "protein_name": "Hyaluronan and proteoglycan link protein 3", "gene_name": "HAPLN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLLLLVPLLLLPGSYGLPFYNGFYYSNSANDQNLGNGHGKDLLNGVKLVVETPEETLFTYQGASVILPCRYRYEPALVSPRRVRVKWWKLSENGAPEKDVLVAIGLRHRSFGDYQGRVHLRQDKEHDVSLEIQDLRLEDYGRYRCEVIDGLEDESGLVELELRGVVFPYQSPNGRYQFNFHEGQQVCAEQAAVVASFEQLFRAWEEGLDWCNAGWLQDATVQYPIMLPRQPCGGPGLAPGVRSYGPRHRRLHRYDVFCFATALKGRVYYLEHPEKLTLTEAREACQEDDATIAKVGQLFAAWKFHGLDRCDAGWLADGSVRYPVVHPHPNCGPPEPGVRSFGFPDPQSRLYGVYCYRQH", "length": 360 }, "evidence": [ { "id": "A0A5G2R305", "url": "https://omabrowser.org/oma/group/A0A5G2R305/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R305", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R305", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" } ], "pmid": "" }, { "name": "perineuronal net", "id": "GO:0072534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072534", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R305", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" } ], "pmid": "" }, { "name": "gel phase of interstitial matrix", "id": "GO:0140150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140150", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R305", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R305", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R305", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R305", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hyaluronic acid binding", "id": "GO:0005540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005540", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R305", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R305-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 470, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R305-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R305" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 158, "end_pos": 274, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R305" }, { "id": "PS50963", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50963" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Link", "eco_id": "ECO_0000259", "start_pos": 276, "end_pos": 371, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 204, "end_pos": 206 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R318-1", "uniprot_ac": "A0A5G2R318", "uniprot_id": "A0A5G2R318_PIG", "mass": { "chemical_mass": 13509.0, "monoisotopic_mass": 13509.0 }, "refseq": {}, "gene_names": [ { "name": "H2AZ2", "type": "recommended", "evidence": [ { "id": "A0A5G2R318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318" } ] } ], "protein_names": [ { "name": "Histone H2A", "type": "recommended", "evidence": [ { "id": "A0A5G2R318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R318", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "H2AZ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318", "locus": { "chromosome": "18", "start_pos": 50552392, "end_pos": 50533429, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016738", "url": "https://www.ensembl.org/id/ENSSSCG00000016738" } ] } } ], "crossref": [ { "id": "A0A5G2R318", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R318", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016738", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016738", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00074", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00074", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MNKKGAP", "url": "https://omabrowser.org/oma/group/MNKKGAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R318", "url": "https://www.orthodb.org/?gene=A0A5G2R318", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23430", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23430", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00125", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16211", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16211", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-110330", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110330", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-110331", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110331", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-171306", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-171306", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-201722", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-212300", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2299718", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2299718", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2559580", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559580", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2559582", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559582", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2559586", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559586", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3214858", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214858", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-427359", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-427359", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5250924", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5250924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5578749", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5578749", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5625886", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5625886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-606279", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-606279", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68616", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73728", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73728", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73772", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73772", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8936459", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8936459", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9018519", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018519", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9670095", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9670095", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9764725", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9764725", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9843940", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9843940", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9843970", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9843970", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9909649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9909649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9940951", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9940951", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9943962", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943962", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UBW2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UBW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QJ24", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QJ24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QJ24-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QJ24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R318", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R318-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBA3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z5P1", "url": "https://www.uniprot.org/uniprotkb/F2Z5P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z5P1-1", "url": "https://www.uniprot.org/uniprotkb/F2Z5P1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA", "length": 128, "header": "tr|A0A5G2R318-1|A0A5G2R318_PIG Isoform 1 of Histone H2A OS=Sus scrofa OX=9823 GN=H2AZ2 PE=1 SV=1 CANONICAL=A0A5G2R318-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UBW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318/entry#A0A4X1UBW2-1", "sequence": { "sequence": "IGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA", "length": 119, "header": "tr|A0A4X1UBW2-1|A0A4X1UBW2_PIG Computationally mapped isoform of Histone H2A OS=Sus scrofa OX=9823 GN=H2AZ2 PE=1 SV=1 CANONICAL=A0A5G2R318-1" }, "locus": { "chromosome": "18", "start_pos": 50546990, "end_pos": 50538749, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075458.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075458.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073685.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073685.1" } ] } }, { "isoform_ac": "A0A5G2QJ24-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318/entry#A0A5G2QJ24-1", "sequence": { "sequence": "MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEA", "length": 66, "header": "tr|A0A5G2QJ24-1|A0A5G2QJ24_PIG Computationally mapped isoform of Histone H2A OS=Sus scrofa OX=9823 GN=H2AZ2 PE=3 SV=2 CANONICAL=A0A5G2R318-1" }, "locus": { "chromosome": "18", "start_pos": 50546934, "end_pos": 50533565, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083043.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083043.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063926.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063926.2" } ] } }, { "isoform_ac": "A0A5G2R318-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318/entry#A0A5G2R318-1", "sequence": { "sequence": "MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA", "length": 128, "header": "tr|A0A5G2R318-1|A0A5G2R318_PIG Isoform 1 of Histone H2A OS=Sus scrofa OX=9823 GN=H2AZ2 PE=1 SV=1 CANONICAL=A0A5G2R318-1" }, "locus": { "chromosome": "18", "start_pos": 50546990, "end_pos": 50533565, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081189.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081189.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064949.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064949.1" } ] } }, { "isoform_ac": "A0A8W4FBA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318/entry#A0A8W4FBA3-1", "sequence": { "sequence": "MAGGKAGKDSGKAKAKAVSRSQRAGLQVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA", "length": 90, "header": "tr|A0A8W4FBA3-1|A0A5G2R318_PIG Computationally mapped isoform of Histone H2A OS=Sus scrofa OX=9823 GN=H2AZ2 PE=1 SV=1 CANONICAL=A0A5G2R318-1" }, "locus": { "chromosome": "18", "start_pos": 50546990, "end_pos": 50533565, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096032.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096032.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076547.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076547.1" } ] } }, { "isoform_ac": "F2Z5P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318/entry#F2Z5P1-1", "sequence": { "sequence": "MFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA", "length": 102, "header": "tr|F2Z5P1-1|F2Z5P1_PIG Computationally mapped isoform of Histone H2A OS=Sus scrofa OX=9823 GN=H2AZ2 PE=1 SV=3 CANONICAL=A0A5G2R318-1" }, "locus": { "chromosome": "18", "start_pos": 50546990, "end_pos": 50533565, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018220.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018220.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017728.4", "url": "https://www.ensembl.org/id/ENSSSCP00000017728.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FBA3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBA3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-110330", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110330", "resource": "Reactome", "description": "Recognition and association of DNA glycosylase with site containing an affected purine" }, { "id": "R-SSC-110331", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110331", "resource": "Reactome", "description": "Cleavage of the damaged purine" }, { "id": "R-SSC-171306", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-171306", "resource": "Reactome", "description": "Packaging Of Telomere Ends" }, { "id": "R-SSC-201722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201722", "resource": "Reactome", "description": "Formation of the beta-catenin:TCF transactivating complex" }, { "id": "R-SSC-212300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212300", "resource": "Reactome", "description": "PRC2 methylates histones and DNA" }, { "id": "R-SSC-2299718", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2299718", "resource": "Reactome", "description": "Condensation of Prophase Chromosomes" }, { "id": "R-SSC-2559580", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559580", "resource": "Reactome", "description": "Oxidative Stress Induced Senescence" }, { "id": "R-SSC-2559582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559582", "resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-SSC-2559586", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559586", "resource": "Reactome", "description": "DNA Damage/Telomere Stress Induced Senescence" }, { "id": "R-SSC-3214858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214858", "resource": "Reactome", "description": "RMTs methylate histone arginines" }, { "id": "R-SSC-427359", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-427359", "resource": "Reactome", "description": "SIRT1 negatively regulates rRNA expression" }, { "id": "R-SSC-5250924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5250924", "resource": "Reactome", "description": "B-WICH complex positively regulates rRNA expression" }, { "id": "R-SSC-5578749", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5578749", "resource": "Reactome", "description": "Transcriptional regulation by small RNAs" }, { "id": "R-SSC-5625886", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5625886", "resource": "Reactome", "description": "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" }, { "id": "R-SSC-606279", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-606279", "resource": "Reactome", "description": "Deposition of new CENPA-containing nucleosomes at the centromere" }, { "id": "R-SSC-68616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68616", "resource": "Reactome", "description": "Assembly of the ORC complex at the origin of replication" }, { "id": "R-SSC-73728", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73728", "resource": "Reactome", "description": "RNA Polymerase I Promoter Opening" }, { "id": "R-SSC-73772", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73772", "resource": "Reactome", "description": "RNA Polymerase I Promoter Escape" }, { "id": "R-SSC-8936459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8936459", "resource": "Reactome", "description": "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" }, { "id": "R-SSC-9018519", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018519", "resource": "Reactome", "description": "Estrogen-dependent gene expression" }, { "id": "R-SSC-9670095", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9670095", "resource": "Reactome", "description": "Inhibition of DNA recombination at telomere" }, { "id": "R-SSC-9764725", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9764725", "resource": "Reactome", "description": "Negative Regulation of CDH1 Gene Transcription" }, { "id": "R-SSC-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" }, { "id": "R-SSC-9843940", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9843940", "resource": "Reactome", "description": "Regulation of endogenous retroelements by KRAB-ZFP proteins" }, { "id": "R-SSC-9843970", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9843970", "resource": "Reactome", "description": "Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex" }, { "id": "R-SSC-9909649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9909649", "resource": "Reactome", "description": "Regulation of PD-L1(CD274) transcription" }, { "id": "R-SSC-9940951", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9940951", "resource": "Reactome", "description": "Interaction of NuRD complexes with transcription factors" }, { "id": "R-SSC-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" }, { "id": "R-SSC-9943962", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943962", "resource": "Reactome", "description": "CHD6, CHD7, CHD8, CHD9 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HMB9-1", "protein_name": "Histone H2A", "gene_name": "LOC100766018", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA", "length": 128 }, "evidence": [ { "id": "A0A5G2R318", "url": "https://omabrowser.org/oma/group/A0A5G2R318/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O23628-1", "protein_name": "Histone H2A variant 1", "gene_name": "H2AV", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGKGGKGLVAAKTMAANKDKDKDKKKPISRSARAGIQFPVGRIHRQLKTRVSAHGRVGATAAVYTASILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDTLIKGTIAGGGVIPHIHKSLINKTTKE", "length": 136 }, "evidence": [ { "id": "A0A5G2R318", "url": "https://omabrowser.org/oma/group/A0A5G2R318/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P02272-1", "protein_name": "Histone H2A.V", "gene_name": "H2AZ2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA", "length": 128 }, "evidence": [ { "id": "A0A5G2R318", "url": "https://omabrowser.org/oma/group/A0A5G2R318/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P08985-1", "protein_name": "Histone H2A.v", "gene_name": "His2Av", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAGGKAGKDSGKAKAKAVSRSARAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKEETVQDPQRKGNVILSQAY", "length": 141 }, "evidence": [ { "id": "A0A5G2R318", "url": "https://omabrowser.org/oma/group/A0A5G2R318/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A5G2R318", "url": "https://omabrowser.org/oma/group/A0A5G2R318/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12692-1", "protein_name": "Histone H2A.Z", "gene_name": "HTZ1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSGKAHGGKGKSGAKDSGSLRSQSSSARAGLQFPVGRIKRYLKRHATGRTRVGSKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDDELDSLIRATIASGGVLPHINKALLLKVEKKGSKK", "length": 134 }, "evidence": [ { "id": "A0A5G2R318", "url": "https://omabrowser.org/oma/group/A0A5G2R318/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q32LA7-1", "protein_name": "Histone H2A.V", "gene_name": "H2AZ2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA", "length": 128 }, "evidence": [ { "id": "A0A5G2R318", "url": "https://omabrowser.org/oma/group/A0A5G2R318/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3THW5-1", "protein_name": "Histone H2A.V", "gene_name": "H2az2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA", "length": 128 }, "evidence": [ { "id": "A0A5G2R318", "url": "https://omabrowser.org/oma/group/A0A5G2R318/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q71PD7-1", "protein_name": "Histone H2A.V", "gene_name": "h2az2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA", "length": 128 }, "evidence": [ { "id": "A0A5G2R318", "url": "https://omabrowser.org/oma/group/A0A5G2R318/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q71UI9-1", "protein_name": "Histone H2A.V", "gene_name": "H2AZ2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA", "length": 128 }, "evidence": [ { "id": "A0A5G2R318", "url": "https://omabrowser.org/oma/group/A0A5G2R318/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R318", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R318", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R318", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R318", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R318", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R318", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R318-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 128, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R318-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R318" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318" }, { "id": "PF00125", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Core Histone H2A/H2B/H3", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 93, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R318" }, { "id": "PF16211", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histone H2A C-terminal", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 127, "start_aa": "Glu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R322-1", "uniprot_ac": "A0A5G2R322", "uniprot_id": "A0A5G2R322_PIG", "mass": { "chemical_mass": 34997.0, "monoisotopic_mass": 34997.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100519707", "type": "recommended", "evidence": [ { "id": "A0A5G2R322", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R322", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R322", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R322", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100519707", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322", "locus": {} } ], "crossref": [ { "id": "A0A5G2R322", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R322", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R322", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R322-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRYMETKNNVTVFILLGLTQNPHMQKVIFVVFLLIYTVSLGGNVLTVVTIATSPLIRCPMYFFLAHLSFIDACYSCTATPKLVVDSLHEKKTSTFHGCMIQIFGEHFFGGADIILLTMMAYDRYVAICKPLYYATIMNRQLCGLLVGVSWLGGFLHAFIQILFIFRLPFCGPNVIDHFMCDLIPLLNLACTDTHTLGLFVAANSGFICLLIFLILVGSYGVILHTLSTQSLEARRKALSTCVSHITAVVIFFVPCIFEYMRPAVTLPFDRAVAVFCTMITPMLNPLIYTLRNAQLKNAIRKLFSRKVISSEI", "length": 312, "header": "tr|A0A5G2R322-1|A0A5G2R322_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100519707 PE=3 SV=1 CANONICAL=A0A5G2R322-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R322-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322/entry#A0A5G2R322-1", "sequence": { "sequence": "MRYMETKNNVTVFILLGLTQNPHMQKVIFVVFLLIYTVSLGGNVLTVVTIATSPLIRCPMYFFLAHLSFIDACYSCTATPKLVVDSLHEKKTSTFHGCMIQIFGEHFFGGADIILLTMMAYDRYVAICKPLYYATIMNRQLCGLLVGVSWLGGFLHAFIQILFIFRLPFCGPNVIDHFMCDLIPLLNLACTDTHTLGLFVAANSGFICLLIFLILVGSYGVILHTLSTQSLEARRKALSTCVSHITAVVIFFVPCIFEYMRPAVTLPFDRAVAVFCTMITPMLNPLIYTLRNAQLKNAIRKLFSRKVISSEI", "length": 312, "header": "tr|A0A5G2R322-1|A0A5G2R322_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100519707 PE=3 SV=1 CANONICAL=A0A5G2R322-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 135248, "end_pos": 134313, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073918.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073918.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064954.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064954.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R322", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R322", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R322", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R322", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R322-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R322-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R322" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R322", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R322" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R357-1", "uniprot_ac": "A0A5G2R357", "uniprot_id": "A0A5G2R357_PIG", "mass": { "chemical_mass": 33348.0, "monoisotopic_mass": 33348.0 }, "refseq": { "ac": "XP_003131275", "name": "ras-related protein Rab-37 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131275" }, "gene_names": [ { "name": "RAB37", "type": "recommended", "evidence": [ { "id": "A0A5G2R357", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ] }, { "name": "RAB37", "type": "synonym", "evidence": [ { "id": "XP_003131275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131275" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A5G2R357", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A5G2R357", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-37 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003131275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131275" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RAB37", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357", "locus": { "chromosome": "12", "start_pos": 6484535, "end_pos": 6494047, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017233", "url": "https://www.ensembl.org/id/ENSSSCG00000017233" } ] } } ], "crossref": [ { "id": "A0A5G2R357", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R357", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017233", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017233", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513620", "url": "https://www.ncbi.nlm.nih.gov/gene/100513620", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513620", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513620", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R357", "url": "https://www.orthodb.org/?gene=A0A5G2R357", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47978", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47978", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131275", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131275", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R357-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7M1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z570", "url": "https://www.uniprot.org/uniprotkb/F2Z570", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z570-1", "url": "https://www.uniprot.org/uniprotkb/F2Z570-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGTPGAAATRDGEAPERSPPCSPSYDLTGKVMLLGDSGVGKTCFLIQFKDGAFLSGTFIATVGIDFRNKVVTVDGVRVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLGNKADVSSERVIRSEDGEMLAREYGVPFMETSAKTGMNVELAFLAIAKELKYRAGRQAEEPSFQIRDYVESQKKRPGCCPSCDSPGPGRQPQRPTRTQPAPSDLISSERLSQWGESWGTQCTAPRSSRPYPSARSFSASPGRVKYLYVILMIPNDIERAP", "length": 301, "header": "tr|A0A5G2R357-1|A0A5G2R357_PIG Isoform 1 of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB37 PE=3 SV=2 CANONICAL=A0A5G2R357-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R357-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357/entry#A0A5G2R357-1", "sequence": { "sequence": "MTGTPGAAATRDGEAPERSPPCSPSYDLTGKVMLLGDSGVGKTCFLIQFKDGAFLSGTFIATVGIDFRNKVVTVDGVRVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLGNKADVSSERVIRSEDGEMLAREYGVPFMETSAKTGMNVELAFLAIAKELKYRAGRQAEEPSFQIRDYVESQKKRPGCCPSCDSPGPGRQPQRPTRTQPAPSDLISSERLSQWGESWGTQCTAPRSSRPYPSARSFSASPGRVKYLYVILMIPNDIERAP", "length": 301, "header": "tr|A0A5G2R357-1|A0A5G2R357_PIG Isoform 1 of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB37 PE=3 SV=2 CANONICAL=A0A5G2R357-1" }, "locus": { "chromosome": "12", "start_pos": 6493411, "end_pos": 6485669, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089386.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089386.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071525.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071525.2" } ] } }, { "isoform_ac": "A0A5G2R7M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357/entry#A0A5G2R7M1-1", "sequence": { "sequence": "MTGTPGAAATRDGEAPERSPPCSPSYDLTGKNKVVTVDGVRVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLGNKADVSSERVIRSEDGEMLAREYGVPFMETSAKTGMNVELAFLAIAKELKYRAGRQAEEPSFQIRDYVESQKKRPGCSFL", "length": 185, "header": "tr|A0A5G2R7M1-1|A0A5G2R357_PIG Computationally mapped isoform of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB37 PE=3 SV=1 CANONICAL=A0A5G2R357-1" }, "locus": { "chromosome": "12", "start_pos": 6493411, "end_pos": 6485904, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084030.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084030.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073247.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073247.1" } ] } }, { "isoform_ac": "F2Z570-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357/entry#F2Z570-1", "sequence": { "sequence": "MRCKVMLLGDSGVGKTCFLIQFKDGAFLSGTFIATVGIDFRNKVVTVDGVRVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLGNKADVSSERVIRSEDGEMLAREYGVPFMETSAKTGMNVELAFLAIAKELKYRAGRQAEEPSFQIRDYVESQKKRPGCSFL", "length": 195, "header": "tr|F2Z570-1|A0A5G2R357_PIG Computationally mapped isoform of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB37 PE=3 SV=3 CANONICAL=A0A5G2R357-1" }, "locus": { "chromosome": "12", "start_pos": 6494047, "end_pos": 6485904, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018760.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018760.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018258.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018258.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F2Z570", "url": "https://www.uniprot.org/uniprotkb/F2Z570" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513620", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513620", "resource": "KEGG Pathway" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ], "pmid": "" }, { "name": "regulation of exocytosis", "id": "GO:0017157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017157", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R357", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R357" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-SSC-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, azurophil granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6798739", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798739" } ] }, { "id": "R-SSC-6799350", "name": "Exocytosis of specific granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, specific granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6799350", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799350" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R357-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 301, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R357-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R357" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R394-1", "uniprot_ac": "A0A5G2R394", "uniprot_id": "A0A5G2R394_PIG", "mass": { "chemical_mass": 117685.0, "monoisotopic_mass": 117685.0 }, "refseq": { "ac": "XP_013833641", "name": "importin-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013833641" }, "gene_names": [ { "name": "IPO4", "type": "recommended", "evidence": [ { "id": "A0A5G2R394", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394" } ] }, { "name": "IPO4", "type": "synonym", "evidence": [ { "id": "XP_013833641", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013833641" } ] } ], "protein_names": [ { "name": "Importin 4", "type": "synonym", "evidence": [ { "id": "A0A5G2R394", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394/entry#names_and_taxonomy" } ] }, { "name": "importin-4", "type": "synonym", "evidence": [ { "id": "XP_013833641", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013833641" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R394", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IPO4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394", "locus": { "chromosome": "7", "start_pos": 75118733, "end_pos": 75110082, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002000", "url": "https://www.ensembl.org/id/ENSSSCG00000002000" } ] } } ], "crossref": [ { "id": "A0A5G2R394", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R394", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002000", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002000", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100157703", "url": "https://www.ncbi.nlm.nih.gov/gene/100157703", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157703", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157703", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMPRIRH", "url": "https://omabrowser.org/oma/group/VMPRIRH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R394", "url": "https://www.orthodb.org/?gene=A0A5G2R394", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10527", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10527", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013833641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013833641", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R394", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R394-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F927", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F927", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F927-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F927-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPAGLEQILQELLLPDTDRIRRATEQLQTALRDPTALPALCDLLTSAGDPQIRQFAAVLTRRRLSTGWRRLVVEQRESLKSLILSALQRETEHSVSLSLAQLSATIFRKEGLEAWPQLMQLLQHSTHSPHIPEREMGLLLLSVVVTSRPEAFRPHHRELLRLLNETLGEVGSPGLLFYSLRTLTTMAPYLGTDDVPLARMLVPRLITAVQALIPVDEAKACEALEALDELLESEVPIITSHLSEVLTFCLEVAKNVALGDAIRVRILCCLTFLVKVKSKALLKNRLLPPLLHTLFPIMAAEPPLGQLDPEDQDSEEEELEIGLVGETPKHFAVQVVDMLALHLPPEKLCPLLMPMLEEALRSENPYQRKAGLLVLAVLSDGAGDHIRQRLLPPLLQIVCKSLEDPSLVVRNAALFTLGQFSENLQPHISSYSGEVMPLLLTYLKSVPSGHTHHLAKACYALENFVENLGPKVQPYLPELMECMLQPLRKPSSPRAKELAVSALGAIATAAQASVLPYFPTIMEQLREFLLTGHEDLQPVRIQSLETLGVLVRAVGEPMRPLAEECCQLGLGLCDQVDDPDLRRCTYSLFAALSGLMGESLAPHLPQITTLMLSSLRSAEGIVPQYDGNSAFLLFDDESDGEEEEELMDEDEEEDSEISGYSVENAFFDEKEDTCAALGEISVNASVAFLPYMETVFEEVFKLLECPHLNVRKAAHEALGQFCCALHKACQSCPSEPNAAALQAALARVVPSYMQAVNGEQERQVVMAVLEALTAVLRGCGNLALQPPGRLAELCHMLKAVLQRKTACQDADEEEEEDQAEYDAMLLEHAGEAIPALAAAAGGDAFAPFFAGFLPLLLCKTKQGCTVAEKSFAVGTLAESIQGLGAASAQFVSRLFPALLSTARETDPEVRSNAIFGLGVLAEHGGRPAQEHFPKLLGLLLPLLARERHDRVHDNICGALARLLMASPTRKPEPQVLAALLHALPLKEDLEEWVTIGHLFSFLHQSSPDQVVDVAPELLRICSLILAENKIPADTKAALLLLLTFLAKQHSDSFYSALGSLPADKAQELQAVLGLT", "length": 1076, "header": "tr|A0A5G2R394-1|A0A5G2R394_PIG Isoform 1 of Importin 4 OS=Sus scrofa OX=9823 GN=IPO4 PE=4 SV=2 CANONICAL=A0A5G2R394-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R394-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394/entry#A0A5G2R394-1", "sequence": { "sequence": "MEPAGLEQILQELLLPDTDRIRRATEQLQTALRDPTALPALCDLLTSAGDPQIRQFAAVLTRRRLSTGWRRLVVEQRESLKSLILSALQRETEHSVSLSLAQLSATIFRKEGLEAWPQLMQLLQHSTHSPHIPEREMGLLLLSVVVTSRPEAFRPHHRELLRLLNETLGEVGSPGLLFYSLRTLTTMAPYLGTDDVPLARMLVPRLITAVQALIPVDEAKACEALEALDELLESEVPIITSHLSEVLTFCLEVAKNVALGDAIRVRILCCLTFLVKVKSKALLKNRLLPPLLHTLFPIMAAEPPLGQLDPEDQDSEEEELEIGLVGETPKHFAVQVVDMLALHLPPEKLCPLLMPMLEEALRSENPYQRKAGLLVLAVLSDGAGDHIRQRLLPPLLQIVCKSLEDPSLVVRNAALFTLGQFSENLQPHISSYSGEVMPLLLTYLKSVPSGHTHHLAKACYALENFVENLGPKVQPYLPELMECMLQPLRKPSSPRAKELAVSALGAIATAAQASVLPYFPTIMEQLREFLLTGHEDLQPVRIQSLETLGVLVRAVGEPMRPLAEECCQLGLGLCDQVDDPDLRRCTYSLFAALSGLMGESLAPHLPQITTLMLSSLRSAEGIVPQYDGNSAFLLFDDESDGEEEEELMDEDEEEDSEISGYSVENAFFDEKEDTCAALGEISVNASVAFLPYMETVFEEVFKLLECPHLNVRKAAHEALGQFCCALHKACQSCPSEPNAAALQAALARVVPSYMQAVNGEQERQVVMAVLEALTAVLRGCGNLALQPPGRLAELCHMLKAVLQRKTACQDADEEEEEDQAEYDAMLLEHAGEAIPALAAAAGGDAFAPFFAGFLPLLLCKTKQGCTVAEKSFAVGTLAESIQGLGAASAQFVSRLFPALLSTARETDPEVRSNAIFGLGVLAEHGGRPAQEHFPKLLGLLLPLLARERHDRVHDNICGALARLLMASPTRKPEPQVLAALLHALPLKEDLEEWVTIGHLFSFLHQSSPDQVVDVAPELLRICSLILAENKIPADTKAALLLLLTFLAKQHSDSFYSALGSLPADKAQELQAVLGLT", "length": 1076, "header": "tr|A0A5G2R394-1|A0A5G2R394_PIG Isoform 1 of Importin 4 OS=Sus scrofa OX=9823 GN=IPO4 PE=4 SV=2 CANONICAL=A0A5G2R394-1" }, "locus": { "chromosome": "7", "start_pos": 75118539, "end_pos": 75110378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069453.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069453.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065019.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065019.2" } ] } }, { "isoform_ac": "A0A8W4F927-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394/entry#A0A8W4F927-1", "sequence": { "sequence": "MEPAGLEQILQELLLPDTDRIRRATEQLQTALRDPTALPALCDLLTSAGDPQIRQFAAVLTRRRLSTGWRRLVVEQRESLKSLILSALQRETEWGFCC", "length": 98, "header": "tr|A0A8W4F927-1|A0A5G2R394_PIG Computationally mapped isoform of Importin 4 OS=Sus scrofa OX=9823 GN=IPO4 PE=4 SV=1 CANONICAL=A0A5G2R394-1" }, "locus": { "chromosome": "7", "start_pos": 75111615, "end_pos": 75110378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097503.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097503.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075821.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075821.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F927", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F927" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157703", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157703", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XBM8-1", "protein_name": "Importin 4", "gene_name": "IPO4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPQYSLLCGVFRFINFRLRRKRPLSKMAAPELQAVLEQLLEPDNAVIQQATARLREAFADPRTPERLAEIVVGAARPQLRQLAAVLLRRRLSGGRWRHLDPELRLRLPSLLAEALEKETDRSVLPSLSHVGAVLLRRGGAEAWAPMGQWVQRAARDPHLQERALQVLSAALEDPPPSLTPHCRPIAELCRGGLQPGTPPHSTAYALKALGGLAAALGGTQTDLLRSLLPDVLRALQALIDADEELGAAALEVLDEFVAADPKAVTFDLRPVLDLCLQVGGAEGRGQAVRARALAVLGFLAQERPRALQPFLPPLLGSLLTLLCSPPPRDHPDPEDAELWGGGEGGRSIRHCAAQVLNALALGVPAEKLLREMVPRLEPLLGSPEPWGRKGALLALGAAADGCGELLRRRYMGAVLGALRRGLRDPEGAVRGAAASALRSVGEYMQPEAAALALEALPAALEALPVSLEPLPGCPEALPGSPEVLPGARSWFVLRELLAVAGAAVAPQLGAVLGALLGVLERGRPHEMELALSALHELGGAVEDFPLCPPGGAVEAALLAVLRLPDPPHRAVRLQAMEVLGALGGGAAALEAVLEMAADGDGEERRVLFGLCGAAAEALREGVEPMLPRLLPLLLHSLQAPPPAASPAASDSFLLFDAAEDEEGAEPMGDEEEELVAVEVGGDFVAEVEAACEGAGLMAEHCGAAFEPYFCPTLEALLPLLEFPHPDVRSAAYGALGGLSCGAGNAVGQQELQGRALTALLGAVRAEKGAGPARAGLTALSRALSPALSPQLLHAIGCLMADVINGQIRCLQDDDGSDEEEVEAAAELRELAGEGLAAVGGASPGGGALSDSFRRALPTLLGCLNGDAAQRSWAAAILGEAGAHLERGVASELLPLIGPALARSSAHDPDPEVRSNALCSIGRLAANGVALGAAWPGLAAIGRALREEGRGRGRDNACGALVRHKGALPDAELLALLLPALPLTEDFEENSAVFGYLLQLQPEQLLPHAEEMPRVCSAIGTGSGDTDLEAAVVGLLQELWRRCPTDVGRGMERLPHSDSVRLRRAMGLDDAAAMTPSTVQ", "length": 1079 }, "evidence": [ { "id": "A0A5G2R394", "url": "https://omabrowser.org/oma/group/A0A5G2R394/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A2D7-1", "protein_name": "Importin 4", "gene_name": "Ipo4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPAGLEQILKELLMPDTERIRRATEQLQTALRDPAALPALCDLLASATDPQIRQFAAVLTRRRLSNRWRRLAPEQRESLKSLVLTALQKETEHYVSVSLAQLSATIFRKEGLQGWPQFMNLLQHSTHSAHSPEKEVGLLLLSVVVSSQPEAFHAHQQELLQLLIETLSEVSFPGVLFYSLRTLTALARYLRPDDVSLARMLVPKVVTALRTLIPLDEVKACEALEALDEMLETELPIITPHLSEVLTFCLEVAKNVALGEAIRVRILCCLTFLVKVKSKALLKNRLLPPLLNALFPIMAAEPPLGQLDPEDQDSDDDDLEIGLMGETPKHFAVQVVDMLALHLPPEKLCPHVMPMLEEALRSEAPYQRKAGFLVLAVLSDGAGDHIRQRLLYPLLQIVCKGLDDPSQVVRNAALFALGQFSENLQPHISSYSEEVMPLLLTYLKSVPMGNTHHLAKACYALENFVENLGPKVQPYLPELMECMLQPLKNPSKARTKELAVSAIGAIATAAQDSLLPYFPTVMEHIREFLLTGHDDLHLVQIQSLETLGVLARALGESMKPLAEECCQLGLGLCIHVDDPDVRRCTYSLFAALSGLMGESLGPYLPQITTLMLLSLRSTEGIVPQYDGISSFLLFEDDSEAEEEEELMDEDMEEEEDDSEISGYSVENAFFDEKEDTCTALGEISMNTSVAFLPFMDAIFDEVYKLLECPHMNVRKAAYEALGQFCCALHKACQRGPSDPNNAALQSSLARAIPSYMQAVKVERERPVVMAVLEALTGVLRTCGALTLQPPGRLSELCNVLKAVLQKKTACQDAEEDDDEDDDQAEYDAMLLEHAGEAIPVLAAAAGGHAFAPFFATFLPLLLCKTKQSCTVAEKSFAVGTLAESIQGLGAASAQFVSRLFPVLLNNAREADPEVRSNAIFGLGVLAEHGGCPAQDHFPKLLGLLLPLLARERHDRVRDNICGALARLLMASPAGKTEPQVLATLLHALPLKEDMEEWVTIGHLFSFLHQNNPDQVVGVASELLRICSLILPDNRIPPDTKAALLLLLTFLAKQHSDSFHTALGSLPDDKARELQAMLGLT", "length": 1081 }, "evidence": [ { "id": "A0A5G2R394", "url": "https://omabrowser.org/oma/group/A0A5G2R394/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VI75-1", "protein_name": "Importin-4", "gene_name": "Ipo4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPAGLEQILKELLLPDTERIRRATEQLQTILRDPAALPALFDLLATATDSQIRQFAAVLTRRRLNNRWRRLAPEQRESLKSLVLTALQKETVHSVSVSLAQLSATIFRKEGLQGWPQFMNLLQHSTHSSHSPEKEVGLLLLSVVVSSQPEAFHAHQHELLQLLNETLSDVSFPGVLFYSLRTLTAIARYVRPDDVSLARMLVPKVVTALRTLIPLDEVKACEALEALDEMLETELPIINPHLSEVLTFCLEVAKNVALGEPLRVRVLCCLTFLVKVKSKALLKNRLVPPLLHALFPLMAAEPPMGQLDPEDQDSDDDDLEIGLMGETPKHFAVQVVDMLALHLPPEKLCPHVMPMLEEALRSEDPYQRKAGFLVLAVLSDGAGDHIRQRLLYPLLQIVCKGLDDPSQIVRNAALFALGQFSENLQPHISSYSEEVMPLLLSYLKSVPMGNTHHLAKACYALENFVENLGPKVQPYLPELMECMLQPLKNPSKARTKELAVSAIGAIATAAQDSLLPYFPTIMDLLREFLLTGHEDFHLVQIQSLETLGVLARALGESMKPLAEECCQLGLGLCIHIDDPDVRRCTYSLFAALSGLMGEGLGPYLPQITTLMLLSLRSTEGIVPQYDGISSFLLFDDDSEAEEEEELMDEDMEEEGDDSEISGYSVENAFFDEKEDTCTALGEISMNTCVAFLPFMDATFDEVYKLLECPHMNVRKSAYEALGQFCCALHKASQRSSSDPSSSPVLQTSLARVMPAYMQAVKVERERPVVMAVLESLTGVLRTCGSLALQPPGRLSELCNVLKAVLQKKTACQDAEEDDDEDDDQAEYDAMLLEHAGEAIPVLAATAGGHAFAPFFATFLPLLLCKTKQSCTVAEKSFAVGTLAESIQGLGTASAQFVSRLFPVLLNNAREADPEVRSNAIFGLGVLAEHGGCPAQDHFPKLLGLLLPLLARERHDRVRDNICGALARVLMASPVGKTEPQVLATLLRALPLKEDMEEWLTIGHLFSFLHQNNPEQVVDVASELLRICSLILPDNRIPPDTKAALLLLLTFLAKQHTDSFHTALGSLPNDKAQELQAMMGLT", "length": 1082 }, "evidence": [ { "id": "A0A5G2R394", "url": "https://omabrowser.org/oma/group/A0A5G2R394/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9I7R5-1", "protein_name": "Apollo, isoform A", "gene_name": "Apl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEAAILDIINGILTIDTERIRESTAKMLKAYENPDSLLVLTQIVMSDRPVQERQVAAVLLKRRVKKLRHWQLVPAEHQAAIKSNMLQVLIAVKEKTVKGTVAFIIGSLVRHEEGEQNSWREEILKFIYERCSSPDPIESERGSSIFSSLMDAAPDQFSDHTDTMFPLLAGILVTAEANGNMATPTVHNMLTGSCFLLPFVSGHSNAEQIVVKAVPLILKALAAFVEKGYSIEFMGAFDIIDSMAEHVPHLLTGNVKLLLEFCLMIARNKQFDASIRVQVLTFVGSLVRLKKKIIMKQKLLQPTLSVLFEVICQDDLEEGDDDYFSSESLSSPSNAAAQTLDLMALHMVPDKFIPPLLDLLEPALQSPEPVLRRSSFICMGVIAEGCSEAIGKKYLEVMLNIIKAGVLDSVMFVRTAAFFALGQFSEFLQPTICKFAPQILPVLFDYLNQLVLELKVGEPDSKHMDRMFYALETFCENLDEDIVPYLPTLMDRLFGVMEPQNSNQMREMALSAIAAVSAAAKENLMPYFPRIMTVLQGCLVKDCPKEMYSQRIQAIDTLAALCRELGKDNIIPLADDTMNFCLMMLEDGPDDPEYRRSIYNLMSSLSSVVNESMASVFPKFIDRIMESVIFSEDMVPNVSDNADDDLALVDAPDIEIDLEHTDDEDDQDAYPVENDYIVEKEEAILSLKEFATHTGAAFAPYLQSAFENVYKMIDHPQGDVRMACIDSICSFITALHKLDDAAGLKRACEIAIPKFAHIMRTDDQVAVVLRMLDVLYDVFKYVPAINSQEHAELIFGCIRDIFTNKMACQFNEESGGGDDECSEESENDEMLFENAANLFPMFGLTLQPELFSLYFGRLYHFYIQRLAKVKERDLPEQRAYIYGALADCCKALKGCCATYFDALRPIFIAGSRDSDAKARQNSYFALGEIVFHSEEKSFESYPTILQALSEAIVRESVPAAMDNICGAVARLIVTNPDSVPLGQVLPVWLNHLPLKDDTVENDVIQKAFRVLYLKARPSIEAHLEQILAITIEASYKRQMPDVETTESAVALIKEIRANYPELFSKVSNMNPEVFNYVQAL", "length": 1080 }, "evidence": [ { "id": "A0A5G2R394", "url": "https://omabrowser.org/oma/group/A0A5G2R394/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R394", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R394", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R394", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R394", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R394", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R394", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394" } ], "pmid": "" }, { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R394", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R394", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R394", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 684, "end_pos": 686, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R394-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1076, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R394-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R394" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R394", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R394" }, { "id": "PS50166", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50166" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Importin N-terminal", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 90, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 684, "end_pos": 686 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3M5-1", "uniprot_ac": "A0A5G2R3M5", "uniprot_id": "A0A5G2R3M5_PIG", "mass": { "chemical_mass": 24091.0, "monoisotopic_mass": 24091.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100625764", "type": "recommended", "evidence": [ { "id": "A0A5G2R3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5" } ] } ], "protein_names": [ { "name": "[phosphatase 2A protein]-leucine-carboxy methyltransferase", "type": "recommended", "evidence": [ { "id": "A0A5G2R3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.233", "type": "synonym", "evidence": [ { "id": "A0A5G2R3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5/entry#names_and_taxonomy" } ] }, { "name": "[Phosphatase 2A protein]-leucine-carboxy methyltransferase 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3M5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5#function" }, { "database": "UniProtKB", "id": "ARBA00003455", "url": "https://www.uniprot.org/uniprotkb/ARBA00003455#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3M5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100625764", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5", "locus": {} } ], "crossref": [ { "id": "A0A5G2R3M5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3M5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045442", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045442", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13600", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13600", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13600:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13600:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04072", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04072", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "48544", "url": "https://www.rhea-db.org/rhea/48544", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R3M5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATSLRRPSFTACSSSLLDADDEGVRGPCEDASLCKRYLRGAGRFAVSIGYWQDPCIPHLVRLSKARKAPEINRGYFAHVHSVSQLIKAFLRKTGCNCQILNLGAGMDTTFWRLKDILLMSTASVSFIKVFLRKTGCNCQILNLGAGMDTTFWRLKDEDLLPSTSWKVDVAGITTRKLHTRAPWHQNQLLADSRADCGRPHVGTAFLSWPLPSLPVP", "length": 217, "header": "tr|A0A5G2R3M5-1|A0A5G2R3M5_PIG Isoform 1 of [phosphatase 2A protein]-leucine-carboxy methyltransferase OS=Sus scrofa OX=9823 GN=LOC100625764 PE=3 SV=2 CANONICAL=A0A5G2R3M5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R3M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5/entry#A0A5G2R3M5-1", "sequence": { "sequence": "MATSLRRPSFTACSSSLLDADDEGVRGPCEDASLCKRYLRGAGRFAVSIGYWQDPCIPHLVRLSKARKAPEINRGYFAHVHSVSQLIKAFLRKTGCNCQILNLGAGMDTTFWRLKDILLMSTASVSFIKVFLRKTGCNCQILNLGAGMDTTFWRLKDEDLLPSTSWKVDVAGITTRKLHTRAPWHQNQLLADSRADCGRPHVGTAFLSWPLPSLPVP", "length": 217, "header": "tr|A0A5G2R3M5-1|A0A5G2R3M5_PIG Isoform 1 of [phosphatase 2A protein]-leucine-carboxy methyltransferase OS=Sus scrofa OX=9823 GN=LOC100625764 PE=3 SV=2 CANONICAL=A0A5G2R3M5-1" }, "locus": { "chromosome": "AEMK02000694.1", "start_pos": 52746, "end_pos": 35265, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066518.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066518.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070942.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070942.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3M5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3M5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of mitotic cell cycle spindle assembly checkpoint", "id": "GO:0090266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090266", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3M5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3M5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein C-terminal leucine carboxyl O-methyltransferase activity", "id": "GO:0018423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018423", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3M5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3M5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48544", "name": "", "equation": "[phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine = [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "48544", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48544" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R3M5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 217, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R3M5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3M5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3S1-1", "uniprot_ac": "A0A5G2R3S1", "uniprot_id": "A0A5G2R3S1_PIG", "mass": { "chemical_mass": 36327.0, "monoisotopic_mass": 36327.0 }, "refseq": {}, "gene_names": [ { "name": "OR51G1", "type": "recommended", "evidence": [ { "id": "A0A5G2R3S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R3S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OR51G1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1", "locus": { "chromosome": "9", "start_pos": 5211472, "end_pos": 5210507, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000053634", "url": "https://www.ensembl.org/id/ENSSSCG00000053634" } ] } } ], "crossref": [ { "id": "A0A5G2R3S1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3S1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15222", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15222", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R3S1", "url": "https://www.orthodb.org/?gene=A0A5G2R3S1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R3S1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTILYNSSLQKATFFLTGFRGLEGLHGWISLPFCSIYLAVIVGNLTVLHVIRTDVTLHEPMYYFLAMLALTDLGLCLSTLPTVMGIFWFGAREIGIPACFTQLFFIHTLSLVESSVLLSMSVDRYVAICHPLRYSTVLTPARIVRMGLSSVLRSALLILPLPFLLKRFQYCRSHVLAHAYCLHLEIMKLACSSITVNHIYGLFVVACTVGVDSLLIFLSYALILRTVLGIASRQERLRALSTCVSHICAVLLFYMPMIGLSLVHRFGEHLPRLVHLLMSYVYLLVTPLMNPIVYSIKTKQIRQRIAKKFQFIKSLKCFQQD", "length": 321, "header": "tr|A0A5G2R3S1-1|A0A5G2R3S1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR51G1 PE=3 SV=1 CANONICAL=A0A5G2R3S1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R3S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1/entry#A0A5G2R3S1-1", "sequence": { "sequence": "MTILYNSSLQKATFFLTGFRGLEGLHGWISLPFCSIYLAVIVGNLTVLHVIRTDVTLHEPMYYFLAMLALTDLGLCLSTLPTVMGIFWFGAREIGIPACFTQLFFIHTLSLVESSVLLSMSVDRYVAICHPLRYSTVLTPARIVRMGLSSVLRSALLILPLPFLLKRFQYCRSHVLAHAYCLHLEIMKLACSSITVNHIYGLFVVACTVGVDSLLIFLSYALILRTVLGIASRQERLRALSTCVSHICAVLLFYMPMIGLSLVHRFGEHLPRLVHLLMSYVYLLVTPLMNPIVYSIKTKQIRQRIAKKFQFIKSLKCFQQD", "length": 321, "header": "tr|A0A5G2R3S1-1|A0A5G2R3S1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR51G1 PE=3 SV=1 CANONICAL=A0A5G2R3S1-1" }, "locus": { "chromosome": "9", "start_pos": 5211469, "end_pos": 5210507, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103573.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103573.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078692.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078692.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R3S1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 321, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R3S1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3S1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R3S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 294, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 44, "end_pos": 46 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3S4-1", "uniprot_ac": "A0A5G2R3S4", "uniprot_id": "A0A5G2R3S4_PIG", "mass": { "chemical_mass": 34443.0, "monoisotopic_mass": 34443.0 }, "refseq": { "ac": "XP_003130053", "name": "olfactory receptor 10G9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130053" }, "gene_names": [ { "name": "LOC100518267", "type": "synonym", "evidence": [ { "id": "XP_003130053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130053" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 10G9", "type": "synonym", "evidence": [ { "id": "XP_003130053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130053" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4", "locus": {} } ], "crossref": [ { "id": "A0A5G2R3S4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3S4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045958", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045958", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100518267", "url": "https://www.ncbi.nlm.nih.gov/gene/100518267", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518267", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518267", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SMNEMVI", "url": "https://omabrowser.org/oma/group/SMNEMVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R3S4", "url": "https://www.orthodb.org/?gene=A0A5G2R3S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003130053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130053", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R3S4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNKSLVTTFILAGLPHPPQLDTLLFATFLLIYVLSVLGNLLILLVITVDPHLHTPMYFFLTNLSFIDMWFSTVTVPKVLMSLVSPAGGALSFHSCVAQLYSFHFLGSTECFLYTVMSYDRYLAISHPLRYSGLMRGRTCALLATTTWLSGALHSAVQTTLTFRLPYCGPSRIQHYFCDAPPILKLACADTSAVEMVIFINIGVVASGCFLLIVLSYVSIVCSILKIRTSEGRHRAFQTCASHCIVVLCFFVPCVFIYLRPGSKAAVDGVVAVFYTVLTPLLNPVVYTLRNKEVKKALLKLKDKVAYSQDK", "length": 311, "header": "tr|A0A5G2R3S4-1|A0A5G2R3S4_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R3S4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R3S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4/entry#A0A5G2R3S4-1", "sequence": { "sequence": "MTNKSLVTTFILAGLPHPPQLDTLLFATFLLIYVLSVLGNLLILLVITVDPHLHTPMYFFLTNLSFIDMWFSTVTVPKVLMSLVSPAGGALSFHSCVAQLYSFHFLGSTECFLYTVMSYDRYLAISHPLRYSGLMRGRTCALLATTTWLSGALHSAVQTTLTFRLPYCGPSRIQHYFCDAPPILKLACADTSAVEMVIFINIGVVASGCFLLIVLSYVSIVCSILKIRTSEGRHRAFQTCASHCIVVLCFFVPCVFIYLRPGSKAAVDGVVAVFYTVLTPLLNPVVYTLRNKEVKKALLKLKDKVAYSQDK", "length": 311, "header": "tr|A0A5G2R3S4-1|A0A5G2R3S4_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R3S4-1" }, "locus": { "chromosome": "9", "start_pos": 50943603, "end_pos": 50942671, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072243.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072243.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065201.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065201.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518267", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518267", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K2S6-1", "protein_name": "Olfactory receptor family 10 subfamily G member 9", "gene_name": "Or10g9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNVTLVTTFFLSGIPHAPALDTMLFVTFLMIYFLTVLGNFLILMVIRVDSHLHTPMYYFLTNLSFIDMWFSTVTVPKMLMTLVSPGGGAISFHSCVAQLYCFHFLGSTECFLYTVMSYDRYLAISYPLRYSSLMSGRVCALLAAGTWLTGSLHSAVQTTLTFRLPYCGPNQIQHYFCDAPPILKLACADTSANEMVIFVNIGVVASGCFFLISLSYVSIVWSILRIRTSEGRHRAFQTCASHCIVVLCFFVPCVFIYLRPGSRDAVDGVVAVFYTVLTPLLNPVVYTLRNKEVKKALFKLKDKVAHSQNQ", "length": 311 }, "evidence": [ { "id": "A0A5G2R3S4", "url": "https://omabrowser.org/oma/group/A0A5G2R3S4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VH10-1", "protein_name": "Olfactory receptor family 10 subfamily G member 9", "gene_name": "Or10g9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNVTLVTTFFLSGIPHPPALDTMLFVAFLVIYILTVLGNFLILMVIRVDSHLHTPMYYFLTNLSFIDMWFSTVTVPKMLMTLVSPRGGAISFHSCVAQLYCFHFLGSTECFLYTVMSYDRYLAISYPLRYSSMMSGRVCALLAAGTWITGSLHSAVQTTLTFRLPYCGPNQIQHYFCDAPPILKLACADTSANEMVIFVNIGVVASGCFLLISLSYVSIVCSILRIRTSEGRHRAFQTCASHCIVVLCFFVPCVFIYLRPGSRDAVDGVVAVFYTVLTPLLNPVVYTLRNKEVKKALVKLKDKVAYSQSQ", "length": 311 }, "evidence": [ { "id": "A0A5G2R3S4", "url": "https://omabrowser.org/oma/group/A0A5G2R3S4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3S4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R3S4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R3S4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3S4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3S4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3T8-1", "uniprot_ac": "A0A5G2R3T8", "uniprot_id": "A0A5G2R3T8_PIG", "mass": { "chemical_mass": 25186.0, "monoisotopic_mass": 25186.0 }, "refseq": {}, "gene_names": [ { "name": "PCSK1N", "type": "recommended", "evidence": [ { "id": "A0A5G2R3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8" } ] } ], "protein_names": [ { "name": "Proprotein convertase subtilisin/kexin type 1 inhibitor", "type": "synonym", "evidence": [ { "id": "A0A5G2R3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3T8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PCSK1N", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8", "locus": { "chromosome": "X", "start_pos": 42947692, "end_pos": 42949024, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021328", "url": "https://www.ensembl.org/id/ENSSSCG00000021328" } ] } } ], "crossref": [ { "id": "A0A5G2R3T8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3T8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000021328", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000021328", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR010832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15531", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15531", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15531:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15531:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07259", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07259", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R3T8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VVLSVSGDIWSSPLALEEPRSLGAASPPMAEAGTPRRFRRAAPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRVWGGPRTNDPALGLEDDPDAPAAQLARALLRARLDPAALAAQLVPAPAPAAALRPRPPVYDDGPTVPDAEDAGDETPDLDPELLRYLLGRILAGSADSEAVAAPRRLRRAADQDLAPEVPPEGVLGALLRVKRLENPAPQAPARRLLP", "length": 238, "header": "tr|A0A5G2R3T8-1|A0A5G2R3T8_PIG Isoform 1 of Proprotein convertase subtilisin/kexin type 1 inhibitor OS=Sus scrofa OX=9823 GN=PCSK1N PE=1 SV=1 CANONICAL=A0A5G2R3T8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R3T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8/entry#A0A5G2R3T8-1", "sequence": { "sequence": "VVLSVSGDIWSSPLALEEPRSLGAASPPMAEAGTPRRFRRAAPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRVWGGPRTNDPALGLEDDPDAPAAQLARALLRARLDPAALAAQLVPAPAPAAALRPRPPVYDDGPTVPDAEDAGDETPDLDPELLRYLLGRILAGSADSEAVAAPRRLRRAADQDLAPEVPPEGVLGALLRVKRLENPAPQAPARRLLP", "length": 238, "header": "tr|A0A5G2R3T8-1|A0A5G2R3T8_PIG Isoform 1 of Proprotein convertase subtilisin/kexin type 1 inhibitor OS=Sus scrofa OX=9823 GN=PCSK1N PE=1 SV=1 CANONICAL=A0A5G2R3T8-1" }, "locus": { "chromosome": "X", "start_pos": 42949024, "end_pos": 42947857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082470.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082470.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068857.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068857.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 155, "start_aa": "Thr", "end_pos": 155, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr155", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3T8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3T8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8" } ], "pmid": "" }, { "name": "endopeptidase inhibitor activity", "id": "GO:0004866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004866", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3T8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3T8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3T8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3T8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3T8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R3T8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 238, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R3T8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3T8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 155 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3X5-1", "uniprot_ac": "A0A5G2R3X5", "uniprot_id": "A0A5G2R3X5_PIG", "mass": { "chemical_mass": 290900.0, "monoisotopic_mass": 290900.0 }, "refseq": {}, "gene_names": [ { "name": "TG", "type": "recommended", "evidence": [ { "id": "A0A5G2R3X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5" } ] } ], "protein_names": [ { "name": "Thyroglobulin", "type": "recommended", "evidence": [ { "id": "A0A5G2R3X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TG", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5", "locus": { "chromosome": "4", "start_pos": 8158396, "end_pos": 8382435, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005948", "url": "https://www.ensembl.org/id/ENSSSCG00000005948" } ] } } ], "crossref": [ { "id": "ENSSSCG00000005948", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005948", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00191", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00191", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14093", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14093", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14093:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14093:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00086", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00086", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R3X5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALALWVFALLGSACLVSANIFEYQVDAQPLRPCELQRERAFLKRADYVPQCAEDGSFQTVQCKKDGGSCWCVDADGREVPGSRQPGRPVACLSFCQLQKQQILLSSYINSTATSYLPQCQDSGAYAPVQCDVRREQCWCVDAEGMEVYGTRRLGRPARCPGSCEIRNRRLLHGVGDKSPPQCSADGTFLPVQCKFVNTTDMMFFDLVHSYNRFPDAFVTFSSFRSRFPEVSGYCHCADSQGRELAGTGLELLLDEIYDTVFAGLDLASSFTETTLYRILQRRFLAVQLVTSGHCRLRGCPTKCEVERFAATSFGHPYVPSCGRDGEYQAGQCQQEGLCWCVDAQGQEIPGTRRPSEPLSCAEGQSCPSERRRALSRLHLGPSGYSGQRGSFLAAERGPVSQTVPSFAASCPLPLKELFVESGILQPVVQGQKKEVTAATESLLKEGLRGIFPSRELARLALQFTANPKRLQQNLFGGRFLANVGQFNLSGALGTRGTFNFSHFFQQLGLPGFQKRQALADPAKSLSVGLDSNPATEAPEALKMGVAMNKTVVGSFGFEVNLQENRNALTFLSSLLELPEFLLFLQHAISVPEDIARDLGDVMEMALSSQGCEQTPGSLFVPSCTAEGSYEDVQCFAGECWCVDARGRELAGSRARGGRPRCPTACEKQRERMQSLLGRQPAGSSVFVPSCTREGHFLPVQCFSSDCYCVDADGQPIPGTRTAPGEPKQCPTPCQLQAEQAFLGTVRGLISNPSEPPVLSSIYIPQCSASGQWRRVQCDGPPEQAFEWYERWGAQSRSGQELTPAELLMKIMSYREAASGSFRLFIQNLYEAGQQGIFPGLARYSSLQDVPLAVLEGNLTQATGNILLEPYLFWQILNGQLPRYPGPYSDFSAPLAHLDLRSCWCVDEAGRKLEGTQTEPSKVPACPGSCEEVKLRVLQFIKEAEEIVMVSNSSQFPLGESFLAAKGIRLTDEELALPPLSPSRETFLEKFLSGSDYAIRLAAQSTFSFYQRRRVALSDAPRTSGPLQPYPYVPQCDALGSWEPVQCHAATGHCWCVDGEGAYLPASLAARSPQVLQCPTPCETSRVRGLLSAWKQAGSQVRPSPKDLFIPACTETGEFARLQASEASTWCVDPASGEAMPPGTNSSAPCPGLCEVLQRGVPSRRASPGTTPACRAEDGGFAPVQCDPAQGSCWCVLGSGEEVPGTRVAGSQPACERPQLWQTIQTRGQFQLQLPPGKVCSADYAGLLPTFQVVILDELTARGFCRIQVTTARTPVSIPVCDDSTVRVGCLSLDRLGVNVTWTLRLEDAPPASLPDLRDIEEALAGKDLVGRFADLIQSGTFQLHLDSRTFPADPSIHFLQGNSLGTSPRTRFGCVEGSRQVPATSNTSQDPLGCVRCPEGSYFQEEQCIPCPAGFYQEQTGSLACAPCPAGTTTTSVGAFSQTHCVTACQRDEAGLQCDQDGQYRASQRDRASGKAFCVDSEGRRLPWSETQAPLVDAQCLMMRKFEKLPESKVIFTADVAVLGSIVPDSESSLMQCLADCARDEACSFLTVSLEGSEGSCDFYAWTSDNIACTSSGQEEDALGTSKATSLGSLTCQVKVRPGDGVAPAVYLKKGQEFATIGQKRFEQTGFQNALSGLYSPVVFSASGASLTEAHLFCLLACDRDSCCDGFILTQVQGGPIICGLLSSPDVLLCHVRDWRDPSEAQADATCPGVTYDQDSRQGTLRLGGQEFKSLTPREGARDTFTSFQQVYLWKDSDMGSRSESMGCRRDMQPRPESPEETDLTAELFSPVDLNQVIVSENRSLPSQQHRLFKHLFSLQQAHLWCLSRCVQEPSFCQLAEITDSSPLYLTCTLYPEAQVCDDVMEASPRGCRRILPRRPNALFQRRVVLQDRVKNFYTRLPFQKLTGLSIRHKVPMADKAISSGFFECERLCDVDPCCTGFGFLNVSQLKGGEVTCLTLNSLGLQTCSEENGGSWRLLACGSPDTEVRTYPFGWYQKPGDDWVSPPYEDDVFGLGIALDSWQPLPPSSVVVDPSIRNFDVAHISTAAVGDFSAARERCLLECSRHQACLVTTLQTRPGAVRCMFYADTQSCTHSLQAQNCQLLLREEATHIYRKPDIPLPGLGSSAPTVTIATHGQLLGTSQAIQLGASWKQVDQFLGVPYAAPPLAESRFRAPEPLNWTGTWDATKPRASCWQPGIRPATAPGVSEDCLYLSVFVPQSLTPNSSVLVFFHNGAEGPLAMAVDGSFLAAVGNLIVVTASYRTGVFGFLSSGSSEVSGNWGLLDQVAALTWVQTHIGVFGGDPRRVALAADRGGADVAGIHLLTSRATNSRLFRRAVLMGGSVLSPAAVIRPDRAQQQAAALKWYPASAGSLPLLAVSGPFHYWGPVVDGQLLREAPARALQRPPRAKLDLLIGSSQDDGLIDRAKAVKRFEESQGRTSSKTAFYQALQNSLGGEAGDPGVQAAATWYYSLEHDTDDYASFSRALEAATRDYFIICPVIDMASHWARTARGNVFMYHAPESYSHGSLELLADVRYAFGLPFYPAYEGQFTQEEKSLSLKIMQYFSNFVRSGNPNYPHEFSRKAPEFAAPWPDFVPGDGAESYKELSVLLPNRQGLKKADCSFWSKYILSLKASADEAEDGPLAESEEEDRPGLTEDLLGLPELASKSYSK", "length": 2671, "header": "tr|A0A5G2R3X5-1|A0A5G2R3X5_PIG Isoform 1 of Thyroglobulin OS=Sus scrofa OX=9823 GN=TG PE=3 SV=2 CANONICAL=A0A5G2R3X5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R3X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5/entry#A0A5G2R3X5-1", "sequence": { "sequence": "MALALWVFALLGSACLVSANIFEYQVDAQPLRPCELQRERAFLKRADYVPQCAEDGSFQTVQCKKDGGSCWCVDADGREVPGSRQPGRPVACLSFCQLQKQQILLSSYINSTATSYLPQCQDSGAYAPVQCDVRREQCWCVDAEGMEVYGTRRLGRPARCPGSCEIRNRRLLHGVGDKSPPQCSADGTFLPVQCKFVNTTDMMFFDLVHSYNRFPDAFVTFSSFRSRFPEVSGYCHCADSQGRELAGTGLELLLDEIYDTVFAGLDLASSFTETTLYRILQRRFLAVQLVTSGHCRLRGCPTKCEVERFAATSFGHPYVPSCGRDGEYQAGQCQQEGLCWCVDAQGQEIPGTRRPSEPLSCAEGQSCPSERRRALSRLHLGPSGYSGQRGSFLAAERGPVSQTVPSFAASCPLPLKELFVESGILQPVVQGQKKEVTAATESLLKEGLRGIFPSRELARLALQFTANPKRLQQNLFGGRFLANVGQFNLSGALGTRGTFNFSHFFQQLGLPGFQKRQALADPAKSLSVGLDSNPATEAPEALKMGVAMNKTVVGSFGFEVNLQENRNALTFLSSLLELPEFLLFLQHAISVPEDIARDLGDVMEMALSSQGCEQTPGSLFVPSCTAEGSYEDVQCFAGECWCVDARGRELAGSRARGGRPRCPTACEKQRERMQSLLGRQPAGSSVFVPSCTREGHFLPVQCFSSDCYCVDADGQPIPGTRTAPGEPKQCPTPCQLQAEQAFLGTVRGLISNPSEPPVLSSIYIPQCSASGQWRRVQCDGPPEQAFEWYERWGAQSRSGQELTPAELLMKIMSYREAASGSFRLFIQNLYEAGQQGIFPGLARYSSLQDVPLAVLEGNLTQATGNILLEPYLFWQILNGQLPRYPGPYSDFSAPLAHLDLRSCWCVDEAGRKLEGTQTEPSKVPACPGSCEEVKLRVLQFIKEAEEIVMVSNSSQFPLGESFLAAKGIRLTDEELALPPLSPSRETFLEKFLSGSDYAIRLAAQSTFSFYQRRRVALSDAPRTSGPLQPYPYVPQCDALGSWEPVQCHAATGHCWCVDGEGAYLPASLAARSPQVLQCPTPCETSRVRGLLSAWKQAGSQVRPSPKDLFIPACTETGEFARLQASEASTWCVDPASGEAMPPGTNSSAPCPGLCEVLQRGVPSRRASPGTTPACRAEDGGFAPVQCDPAQGSCWCVLGSGEEVPGTRVAGSQPACERPQLWQTIQTRGQFQLQLPPGKVCSADYAGLLPTFQVVILDELTARGFCRIQVTTARTPVSIPVCDDSTVRVGCLSLDRLGVNVTWTLRLEDAPPASLPDLRDIEEALAGKDLVGRFADLIQSGTFQLHLDSRTFPADPSIHFLQGNSLGTSPRTRFGCVEGSRQVPATSNTSQDPLGCVRCPEGSYFQEEQCIPCPAGFYQEQTGSLACAPCPAGTTTTSVGAFSQTHCVTACQRDEAGLQCDQDGQYRASQRDRASGKAFCVDSEGRRLPWSETQAPLVDAQCLMMRKFEKLPESKVIFTADVAVLGSIVPDSESSLMQCLADCARDEACSFLTVSLEGSEGSCDFYAWTSDNIACTSSGQEEDALGTSKATSLGSLTCQVKVRPGDGVAPAVYLKKGQEFATIGQKRFEQTGFQNALSGLYSPVVFSASGASLTEAHLFCLLACDRDSCCDGFILTQVQGGPIICGLLSSPDVLLCHVRDWRDPSEAQADATCPGVTYDQDSRQGTLRLGGQEFKSLTPREGARDTFTSFQQVYLWKDSDMGSRSESMGCRRDMQPRPESPEETDLTAELFSPVDLNQVIVSENRSLPSQQHRLFKHLFSLQQAHLWCLSRCVQEPSFCQLAEITDSSPLYLTCTLYPEAQVCDDVMEASPRGCRRILPRRPNALFQRRVVLQDRVKNFYTRLPFQKLTGLSIRHKVPMADKAISSGFFECERLCDVDPCCTGFGFLNVSQLKGGEVTCLTLNSLGLQTCSEENGGSWRLLACGSPDTEVRTYPFGWYQKPGDDWVSPPYEDDVFGLGIALDSWQPLPPSSVVVDPSIRNFDVAHISTAAVGDFSAARERCLLECSRHQACLVTTLQTRPGAVRCMFYADTQSCTHSLQAQNCQLLLREEATHIYRKPDIPLPGLGSSAPTVTIATHGQLLGTSQAIQLGASWKQVDQFLGVPYAAPPLAESRFRAPEPLNWTGTWDATKPRASCWQPGIRPATAPGVSEDCLYLSVFVPQSLTPNSSVLVFFHNGAEGPLAMAVDGSFLAAVGNLIVVTASYRTGVFGFLSSGSSEVSGNWGLLDQVAALTWVQTHIGVFGGDPRRVALAADRGGADVAGIHLLTSRATNSRLFRRAVLMGGSVLSPAAVIRPDRAQQQAAALKWYPASAGSLPLLAVSGPFHYWGPVVDGQLLREAPARALQRPPRAKLDLLIGSSQDDGLIDRAKAVKRFEESQGRTSSKTAFYQALQNSLGGEAGDPGVQAAATWYYSLEHDTDDYASFSRALEAATRDYFIICPVIDMASHWARTARGNVFMYHAPESYSHGSLELLADVRYAFGLPFYPAYEGQFTQEEKSLSLKIMQYFSNFVRSGNPNYPHEFSRKAPEFAAPWPDFVPGDGAESYKELSVLLPNRQGLKKADCSFWSKYILSLKASADEAEDGPLAESEEEDRPGLTEDLLGLPELASKSYSK", "length": 2671, "header": "tr|A0A5G2R3X5-1|A0A5G2R3X5_PIG Isoform 1 of Thyroglobulin OS=Sus scrofa OX=9823 GN=TG PE=3 SV=2 CANONICAL=A0A5G2R3X5-1" }, "locus": { "chromosome": "4", "start_pos": 8382392, "end_pos": 8158500, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072365.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072365.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068892.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068892.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "thyroid gland development", "id": "GO:0030878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030878", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5" } ], "pmid": "" }, { "name": "hormone biosynthetic process", "id": "GO:0042446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042446", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5" } ], "pmid": "" }, { "name": "thyroid hormone generation", "id": "GO:0006590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006590", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5" } ], "pmid": "" }, { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3X5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1145, "end_pos": 1147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1299, "end_pos": 1301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1387, "end_pos": 1389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1803, "end_pos": 1805, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1947, "end_pos": 1949, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2180, "end_pos": 2182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2225, "end_pos": 2227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" }, { "start_pos": 858, "end_pos": 860, "annotation": "n_glycosylation_sequon" }, { "start_pos": 952, "end_pos": 954, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R3X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3X5" }, { "id": "PS51162", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51162" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thyroglobulin type-1", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 92, "start_aa": "Leu", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 1145, "end_pos": 1147 }, { "start_pos": 1299, "end_pos": 1301 }, { "start_pos": 1387, "end_pos": 1389 }, { "start_pos": 1803, "end_pos": 1805 }, { "start_pos": 1947, "end_pos": 1949 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 2180, "end_pos": 2182 }, { "start_pos": 2225, "end_pos": 2227 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 549, "end_pos": 551 }, { "start_pos": 858, "end_pos": 860 }, { "start_pos": 952, "end_pos": 954 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3Z0-1", "uniprot_ac": "A0A5G2R3Z0", "uniprot_id": "A0A5G2R3Z0_PIG", "mass": { "chemical_mass": 23054.0, "monoisotopic_mass": 23054.0 }, "refseq": {}, "gene_names": [ { "name": "FXN", "type": "recommended", "evidence": [ { "id": "A0A5G2R3Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ] } ], "protein_names": [ { "name": "Frataxin, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A5G2R3Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0/entry#names_and_taxonomy" } ] }, { "name": "1.16.3.1", "type": "synonym", "evidence": [ { "id": "A0A5G2R3Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Modulates the RNA-binding activity of ACO1. May be involved in the cytoplasmic iron-sulfur protein biogenesis. May contribute to oxidative stress resistance and overall cell survival.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0#function" }, { "database": "UniProtKB", "id": "ARBA00045532", "url": "https://www.uniprot.org/uniprotkb/ARBA00045532#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FXN", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0", "locus": { "chromosome": "1", "start_pos": 222434702, "end_pos": 222412509, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000032999", "url": "https://www.ensembl.org/id/ENSSSCG00000032999" } ] } } ], "crossref": [ { "id": "A0A5G2R3Z0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3Z0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000032999", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000032999", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00503", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00503", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002908", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002908", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16821", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16821", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16821:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16821:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01491", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01491", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1268020", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1268020", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1362409", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1362409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9854311", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9854311", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9865881", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9865881", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "11148", "url": "https://www.rhea-db.org/rhea/11148", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UP83", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UP83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UP83-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UP83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWTLGRRAAAGFLPRSGPRGSAQARAGAPRPTKDPQPYGCRGLRTGTAAARARNQSSVSLRCLNQILNVKKQSICLMNLRTTGTLGNAGSLDDTTYERLAEETLDSLAEFFEDLADKPFTFEDYDVSFGSGVLTIKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGNWVYSHDGVSLHELLAKLTTALKTKLDLSSLAYSGKGTCCPA", "length": 213, "header": "tr|A0A5G2R3Z0-1|A0A5G2R3Z0_PIG Isoform 1 of Frataxin, mitochondrial OS=Sus scrofa OX=9823 GN=FXN PE=1 SV=2 CANONICAL=A0A5G2R3Z0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R3Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0/entry#A0A5G2R3Z0-1", "sequence": { "sequence": "MWTLGRRAAAGFLPRSGPRGSAQARAGAPRPTKDPQPYGCRGLRTGTAAARARNQSSVSLRCLNQILNVKKQSICLMNLRTTGTLGNAGSLDDTTYERLAEETLDSLAEFFEDLADKPFTFEDYDVSFGSGVLTIKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGNWVYSHDGVSLHELLAKLTTALKTKLDLSSLAYSGKGTCCPA", "length": 213, "header": "tr|A0A5G2R3Z0-1|A0A5G2R3Z0_PIG Isoform 1 of Frataxin, mitochondrial OS=Sus scrofa OX=9823 GN=FXN PE=1 SV=2 CANONICAL=A0A5G2R3Z0-1" }, "locus": { "chromosome": "1", "start_pos": 222433080, "end_pos": 222412525, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087947.3", "url": "https://www.ensembl.org/id/ENSSSCT00000087947.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068908.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068908.2" } ] } }, { "isoform_ac": "A0ABB5UP83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0/entry#A0ABB5UP83-1", "sequence": { "sequence": "MWTLGRRAAAGFLPRSGPRGSAQARAGAPRPTKDPQPYGCRGLRTGTAAARARNQSSVSLRCLNQILNVKKQSICLMNLRTTGTLGNAGSLDDTTYERLAEETLDSLAEFFEDLADKPFTFEDYDVSFGWRFNH", "length": 134, "header": "tr|A0ABB5UP83-1|A0ABB5UP83_PIG Computationally mapped isoform of Frataxin OS=Sus scrofa OX=9823 GN=FXN PE=3 SV=1 CANONICAL=A0A5G2R3Z0-1" }, "locus": { "chromosome": "1", "start_pos": 222428836, "end_pos": 222412525, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107619.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107619.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082010.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082010.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1268020", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1268020", "resource": "Reactome", "description": "Mitochondrial protein import" }, { "id": "R-SSC-1362409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1362409", "resource": "Reactome", "description": "Mitochondrial iron-sulfur cluster biogenesis" }, { "id": "R-SSC-9854311", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9854311", "resource": "Reactome", "description": "Maturation of TCA enzymes and regulation of TCA cycle" }, { "id": "R-SSC-9865881", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9865881", "resource": "Reactome", "description": "Complex III assembly" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "cellular response to hydrogen peroxide", "id": "GO:0070301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "protein autoprocessing", "id": "GO:0016540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016540", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "negative regulation of release of cytochrome c from mitochondria", "id": "GO:0090201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090201", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "response to iron ion", "id": "GO:0010039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010039", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "heme biosynthetic process", "id": "GO:0006783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "[2Fe-2S] cluster assembly", "id": "GO:0044571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044571", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "[4Fe-4S] cluster assembly", "id": "GO:0044572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044572", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "mitochondrial [2Fe-2S] assembly complex", "id": "GO:0099128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099128", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "ferroxidase activity", "id": "GO:0004322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004322", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "iron chaperone activity", "id": "GO:0034986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034986", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" }, { "name": "ferric iron binding", "id": "GO:0008199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008199", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Z0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11148", "name": "", "equation": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "11148", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11148" } ] }, { "id": "R-SSC-1362408", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-379721" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1362408", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1362408" } ] }, { "id": "R-SSC-1362416", "name": "Frataxin binds iron", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1362416", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1362416" } ] }, { "id": "R-SSC-8986181", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8986181", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8986181" } ] }, { "id": "R-SSC-9854405", "name": "Frataxin transfers Fe2+ to ACO2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9854405", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9854405" } ] }, { "id": "R-SSC-9854984", "name": "Transfer of Fe-S clusters to SDHB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-SSC-9854983", "R-SSC-9854988", "R-SSC-9855015" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9854984", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9854984" } ] }, { "id": "R-SSC-9866272", "name": "2Fe-2S is inserted in UQCRFS1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9866272", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9866272" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-379721", "participant_name": "L-Cys [mitochondrial matrix]", "crossref": [ { "id": "35235", "database": "ChEBI", "url": "" }, { "id": "ZINC000000895042", "database": "ZINC", "url": "" }, { "id": "C00097", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-SSC-9854983", "participant_name": "SDHB [mitochondrial matrix]", "crossref": [ { "id": "A0A5G2R1P2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000020926", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000071101", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000071276", "database": "ENSEMBL", "url": "" }, { "id": "92659", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9854988", "participant_name": "SDHAF1 [mitochondrial matrix]", "crossref": [ { "id": "F1RLD9", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000056787", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000076583", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000098269", "database": "ENSEMBL", "url": "" }, { "id": "XP_013853820.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9855015", "participant_name": "SDHAF3 [mitochondrial matrix]", "crossref": [ { "id": "I3LTJ4", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000023850", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000027441", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000028067", "database": "ENSEMBL", "url": "" }, { "id": "XP_020919045.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R3Z0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 213, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R3Z0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R3Z0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R420-1", "uniprot_ac": "A0A5G2R420", "uniprot_id": "A0A5G2R420_PIG", "mass": { "chemical_mass": 123926.0, "monoisotopic_mass": 123926.0 }, "refseq": {}, "gene_names": [ { "name": "PELP1", "type": "recommended", "evidence": [ { "id": "A0A5G2R420", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ] } ], "protein_names": [ { "name": "Proline-, glutamic acid- and leucine-rich protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2R420", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420/entry#names_and_taxonomy" } ] }, { "name": "Modulator of non-genomic activity of estrogen receptor", "type": "synonym", "evidence": [ { "id": "A0A5G2R420", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PELP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420", "locus": { "chromosome": "12", "start_pos": 52232420, "end_pos": 52177094, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017924", "url": "https://www.ensembl.org/id/ENSSSCG00000017924" } ] } } ], "crossref": [ { "id": "A0A5G2R420", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R420", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017924", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017924", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR012583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR34105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34105:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34105:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08166", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08166", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08167", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08167", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R420-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F864", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F864", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F864-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F864-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RFT3", "url": "https://www.uniprot.org/uniprotkb/F1RFT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RFT3-1", "url": "https://www.uniprot.org/uniprotkb/F1RFT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLSSPNAVQPPCTQRARPRPPPHAPSPRGVRRGVFASSRHATTTVRVKMAAAVLSGPSAGSAAGVPGGTGGLSAVVSVPRLRLLLLDSVSGLLQPRAGSTVAPVHPPAPSAPHLPGLMCLLRLHGTVGGAPNLSAVGALVGLSNARLGSIKTRFEGLCLLSLLVGESPTEMFQQHCVSWLRSIQQVLQSQDPPPTMELAVAVLKDLLRYAAQLPTLFRDISMNHLPGLLTSLLGLRPECELSALEGMKACMTYFPRACGSLKGKLASFFLSRVDALSPQLQQLACECYSRLPSLGAGFSQGLKHTESWEQELHSLLASLHGLLGALYEGAETAPMQYEGPAVEALLSPSEDGDAHVLLRLRQRFSGLARCLGLLLSSEFGAPVSVPVQEVLDVICRTLSVSARNISLLGDGPLRLLLLPSLHLEALDLLSALILACGGRLLRFGALISRLLPQVLSAWSIGRDTLSPGQERPYSTMRTKVYAVLELWVQVCGASAGVLQGGASGEALLTHLLSDISPPADALKLRSPRGSPDGGLQTGKPSAPKKLKLDMGEPIAPPSHRKGDSNANSDVCAAALRGLSRTILMCGPLIKEETHRRLHELVLPLVMGVQQGEVLGSSPYTSSRCRRELYRLLLALLLAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPTLQSMVPTCPTPAAVPPPEAPSPFRAPAFHPPGPMPSAGPMPSGPMPSAGPMPSVGPMPPARPGPPATANHLGLSGSSLVSVPPRLLPGPENHRAGSNEEPVLAPSGTPPPTLPSDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGTTPPPVAPAGPPAASPPVPAKEEPEELPAAPGPLPPPPPTPVPGPATLPPPQLVPEGTPGGGGAPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEDEEEEEEEELEEVEELEFGSAGAEVEEGGPPPPSLPPALPPAESPKVQPEPEPEPGLLLEVEEPGAEEAPGPETAPTLVPEALPAQGEAEREAGSPPTAPPPQELVEEEPSVPPTLLEEGAEGGGDKVPPPPETSAAEEMETETESTALQEKEQDDTAAMLADFIDCPPDDEKPPPAAEPDS", "length": 1176, "header": "tr|A0A5G2R420-1|A0A5G2R420_PIG Isoform 1 of Proline-, glutamic acid- and leucine-rich protein 1 OS=Sus scrofa OX=9823 GN=PELP1 PE=1 SV=2 CANONICAL=A0A5G2R420-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R420-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420/entry#A0A5G2R420-1", "sequence": { "sequence": "MLLSSPNAVQPPCTQRARPRPPPHAPSPRGVRRGVFASSRHATTTVRVKMAAAVLSGPSAGSAAGVPGGTGGLSAVVSVPRLRLLLLDSVSGLLQPRAGSTVAPVHPPAPSAPHLPGLMCLLRLHGTVGGAPNLSAVGALVGLSNARLGSIKTRFEGLCLLSLLVGESPTEMFQQHCVSWLRSIQQVLQSQDPPPTMELAVAVLKDLLRYAAQLPTLFRDISMNHLPGLLTSLLGLRPECELSALEGMKACMTYFPRACGSLKGKLASFFLSRVDALSPQLQQLACECYSRLPSLGAGFSQGLKHTESWEQELHSLLASLHGLLGALYEGAETAPMQYEGPAVEALLSPSEDGDAHVLLRLRQRFSGLARCLGLLLSSEFGAPVSVPVQEVLDVICRTLSVSARNISLLGDGPLRLLLLPSLHLEALDLLSALILACGGRLLRFGALISRLLPQVLSAWSIGRDTLSPGQERPYSTMRTKVYAVLELWVQVCGASAGVLQGGASGEALLTHLLSDISPPADALKLRSPRGSPDGGLQTGKPSAPKKLKLDMGEPIAPPSHRKGDSNANSDVCAAALRGLSRTILMCGPLIKEETHRRLHELVLPLVMGVQQGEVLGSSPYTSSRCRRELYRLLLALLLAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPTLQSMVPTCPTPAAVPPPEAPSPFRAPAFHPPGPMPSAGPMPSGPMPSAGPMPSVGPMPPARPGPPATANHLGLSGSSLVSVPPRLLPGPENHRAGSNEEPVLAPSGTPPPTLPSDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGTTPPPVAPAGPPAASPPVPAKEEPEELPAAPGPLPPPPPTPVPGPATLPPPQLVPEGTPGGGGAPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEDEEEEEEEELEEVEELEFGSAGAEVEEGGPPPPSLPPALPPAESPKVQPEPEPEPGLLLEVEEPGAEEAPGPETAPTLVPEALPAQGEAEREAGSPPTAPPPQELVEEEPSVPPTLLEEGAEGGGDKVPPPPETSAAEEMETETESTALQEKEQDDTAAMLADFIDCPPDDEKPPPAAEPDS", "length": 1176, "header": "tr|A0A5G2R420-1|A0A5G2R420_PIG Isoform 1 of Proline-, glutamic acid- and leucine-rich protein 1 OS=Sus scrofa OX=9823 GN=PELP1 PE=1 SV=2 CANONICAL=A0A5G2R420-1" }, "locus": { "chromosome": "12", "start_pos": 52229367, "end_pos": 52177094, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075280.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075280.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068939.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068939.2" } ] } }, { "isoform_ac": "A0A8W4F864-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420/entry#A0A8W4F864-1", "sequence": { "sequence": "MCLLRLHGTVGGAPNLSAVGALVGLSNARLGSIKTRFEGLCLLSLLVGESPTEMFQQHCVSWLRSIQQVLQSQDPPPTMELAVAVLKDLLRYAAQLPTLFRDISMNHLPGLLTSLLGLRPECELSALEGMKACMTYFPRACGSLKGKLASFFLSRVDALSPQLQQLACECYSRLPSLGAGFSQGLKHTESWEQELHSLLASLHGLLGALYEGAETAPMQYEGPAVEALLSPSEDGDAHVLLRLRQRFSGLARCLGLLLSSEFGAPVSVPVQEVLDVICRTLSVSARNISLLGDGPLRLLLLPSLHLEALDLLSALILACGGRLLRFGALISRLLPQVLSAWSIGRDTLSPGQERPYSTMRTKVYAVLELWVQVCGASAGVLQGGASGEALLTHLLSDISPPADALKLRSPRGSPDGGLQTGKPSAPKKLKLDMGEPIAPPSHRKGDSNANSDVCAAALRGLSRTILMCGPLIKEETHRRLHELVLPLVMGVQQGEVLGSSPYTSSRCRRELYRLLLALLLAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPTLQSMVPTCPTPAAVPPPEAPSPFRAPAFHPPGPMPSAGPMPSGPMPSAGPMPSVGPMPPARPGPPATANHLGLSGSSLVSVPPRLLPGPENHRAGSNEEPVLAPSGTPPPTLPSDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGTTPPPVAPAGPPAASPPVPAKEEPEELPAAPGPLPPPPPTPVPGPATLPPPQLVPEGTPGGGGAPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEDEEEEEEEELEEAEREAGSPPTAPPPQELVEEEPSVPPTLLEEGAEGGGDKVPPPPETSAAEEMETETESTALQEKEQDDTAAMLADFIDCPPDDEKPPPAAEPDS", "length": 982, "header": "tr|A0A8W4F864-1|A0A5G2R420_PIG Computationally mapped isoform of Proline-, glutamic acid- and leucine-rich protein 1 OS=Sus scrofa OX=9823 GN=PELP1 PE=1 SV=1 CANONICAL=A0A5G2R420-1" }, "locus": { "chromosome": "12", "start_pos": 52229367, "end_pos": 52177450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104950.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104950.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074994.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074994.1" } ] } }, { "isoform_ac": "F1RFT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420/entry#F1RFT3-1", "sequence": { "sequence": "MAAAVLSGPSAGSAAGVPGGTGGLSAVVSVPRLRLLLLDSVSGLLQPRAGSTVAPVHPPAPSAPHLPGLMCLLRLHGTVGGAPLSLQSSHPPLIITHLFLVRFEGLCLLSLLVGESPTEMFQQHCVSWLRSIQQVLQSQDPPPTMELAVAVLKDLLRYAAQLPTLFRDISMNHLPGLLTSLLGLRPECELSALEGMKACMTYFPRACGSLKGKLASFFLSRVDALSPQLQQLACECYSRLPSLGAGFSQGLKHTESWEQELHSLLASLHGLLGALYEGAETAPMQYEGPAVEALLSPSEDGDAHVLLRLRQRFSGLARCLGLLLSSEFGAPVSVPVQEVLDVICRTLSVSARNISLLGDGPLRLLLLPSLHLEALDLLSALILACGGRLLRFGALISRLLPQVLSAWSIGRDTLSPGQERPYSTMRTKVYAVLELWVQVCGASAGVLQGGASGEALLTHLLSDISPPADALKLRSPRGSPDGGLQTGKPSAPKKLKLDMGEPIAPPSHRKGDSNANSDVCAAALRGLSRTILMCGPLIKEETHRRLHELVLPLVMGVQQGEVLGSSPYTSSRCRRELYRLLLALLLAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPTLQSMVPTCPTPAAVPPPEAPSPFRAPAFHPPGPMPSAGPMPSAAPCPRRAPSTANHLGLSGSSLVSVPPRLLPGPENHRAGSNEEPVLAPSGTPPPTLPSDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGTTPPPVAPAGPPAASPPVPAKEEPEELPAAPGPLPPPPPTPVPGPATLPPPQLVPEGTPGGGGAPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEDEEEEEEEELEEVEELEFGSAGAEVEEGGPPPPSLPPALPPAESPKVQPEPEPEPGLLLEVEEPGAEEAPGPETAPTLVPEALPAQGEAEREAGSPPTAPPPQELVEEEPSVPPTLLEEGAEGGGDKVPPPPETSAAEEMETETESTALQEKVSGPGGKVGRLREGAVAACAA", "length": 1101, "header": "tr|F1RFT3-1|A0A5G2R420_PIG Computationally mapped isoform of Proline-, glutamic acid- and leucine-rich protein 1 OS=Sus scrofa OX=9823 GN=PELP1 PE=1 SV=4 CANONICAL=A0A5G2R420-1" }, "locus": { "chromosome": "12", "start_pos": 52229222, "end_pos": 52177243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019507.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019507.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018989.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018989.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 697, "start_aa": "Thr", "end_pos": 697, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr697", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 794, "start_aa": "Thr", "end_pos": 794, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr794", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 894, "start_aa": "Thr", "end_pos": 894, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr894", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 912, "start_aa": "Thr", "end_pos": 912, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr912", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F864", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F864" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "pmid": "" }, { "name": "SUMO binding", "id": "GO:0032183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032183", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "pmid": "" }, { "name": "MLL1 complex", "id": "GO:0071339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071339", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R420", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 931, "end_pos": 933, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R420-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1176, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R420-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R420" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R420", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" }, { "id": "PF08166", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08166" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PELP1 middle", "eco_id": "ECO_0000259", "start_pos": 473, "end_pos": 527, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R420", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R420" }, { "id": "PF08167", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08167" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pre-rRNA-processing protein RIX1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 115, "end_pos": 275, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 697, 794, 894, 912 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 931, "end_pos": 933 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R422-1", "uniprot_ac": "A0A5G2R422", "uniprot_id": "A0A5G2R422_PIG", "mass": { "chemical_mass": 34801.0, "monoisotopic_mass": 34801.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110259035", "type": "recommended", "evidence": [ { "id": "A0A5G2R422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R422", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R422", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259035", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422", "locus": {} } ], "crossref": [ { "id": "A0A5G2R422", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R422", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R422", "url": "https://www.orthodb.org/?gene=A0A5G2R422", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R422", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R422-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPENDTQISEFYLLGLSKEPELQPLIFGLFLSMYLITVFGNLLIMLAVSLDSQLHTPMYFFLSNLSFVDICFTSTTIPKMLQNIWTQNKVITYEGCIIQMYFFILFATLDMLLLTVMAYDRFVAICHPLHYTVIMKPLLCGLLVLASWIMTALNSLLQSIMVSWLSFCTELEIPHFFCEINQVVQLACSDTSLNDIVMYFAAGVYAGASLTGILYSYSKIVSSIRKISSVQGKYKAFSTCASHLSVVSLFYCTVLGVYLSVSATHSSHSSAVASVMYTVVTPMLNPFIYSLRNKDIKRALRRITGMAAM", "length": 310, "header": "tr|A0A5G2R422-1|A0A5G2R422_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259035 PE=3 SV=1 CANONICAL=A0A5G2R422-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R422-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422/entry#A0A5G2R422-1", "sequence": { "sequence": "MKPENDTQISEFYLLGLSKEPELQPLIFGLFLSMYLITVFGNLLIMLAVSLDSQLHTPMYFFLSNLSFVDICFTSTTIPKMLQNIWTQNKVITYEGCIIQMYFFILFATLDMLLLTVMAYDRFVAICHPLHYTVIMKPLLCGLLVLASWIMTALNSLLQSIMVSWLSFCTELEIPHFFCEINQVVQLACSDTSLNDIVMYFAAGVYAGASLTGILYSYSKIVSSIRKISSVQGKYKAFSTCASHLSVVSLFYCTVLGVYLSVSATHSSHSSAVASVMYTVVTPMLNPFIYSLRNKDIKRALRRITGMAAM", "length": 310, "header": "tr|A0A5G2R422-1|A0A5G2R422_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259035 PE=3 SV=1 CANONICAL=A0A5G2R422-1" }, "locus": { "chromosome": "AEMK02000630.1", "start_pos": 313824, "end_pos": 312895, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068810.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068810.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071958.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071958.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R422", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R422", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R422", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R422", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R422", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R422-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R422-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R422" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R422" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R433-1", "uniprot_ac": "A0A5G2R433", "uniprot_id": "A0A5G2R433_PIG", "mass": { "chemical_mass": 35297.0, "monoisotopic_mass": 35297.0 }, "refseq": { "ac": "XP_013836624", "name": "olfactory receptor 5H8-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836624" }, "gene_names": [ { "name": "LOC100621954", "type": "recommended", "evidence": [ { "id": "A0A5G2R433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433" } ] }, { "name": "LOC100621954", "type": "synonym", "evidence": [ { "id": "XP_013836624", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836624" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5H8-like", "type": "synonym", "evidence": [ { "id": "XP_013836624", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836624" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R433", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R433", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100621954", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433", "locus": {} } ], "crossref": [ { "id": "A0A5G2R433", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R433", "database": "AlphaFoldDB", "categories": [] }, { "id": "100621954", "url": "https://www.ncbi.nlm.nih.gov/gene/100621954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621954", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621954", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HQSDCKI", "url": "https://omabrowser.org/oma/group/HQSDCKI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R433", "url": "https://www.orthodb.org/?gene=A0A5G2R433", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013836624", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836624", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R433", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R433-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAKNATELTEFVLTGLKYQSEWQIPLFLLFSMIYLITLLGNLGLIALICNDPHLHIPMYLFLGNLAFVDTWLSSTVTPNMLVNFFAKSKMISFSECVVQFFSFAICVTTECFLLATMAYDRYVAICKPLLYPVIMTNRLCMWLLVLSFLGGLFHATFHNAFLFRLTFCDSIIIHHFYCDIIPLFKISCTDPSINYLMVFIFAGIIQAFTISVVLVSYTFVFFTVLKKRSLQGIRKAFSTCGAHLLSVSLYYGPLLFMYVLPGSAQENDGDMMDSLFYTVIIPFLNSIIYSLRNKKVIDSLTKMLKRNV", "length": 309, "header": "tr|A0A5G2R433-1|A0A5G2R433_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100621954 PE=3 SV=1 CANONICAL=A0A5G2R433-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R433-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433/entry#A0A5G2R433-1", "sequence": { "sequence": "MEAKNATELTEFVLTGLKYQSEWQIPLFLLFSMIYLITLLGNLGLIALICNDPHLHIPMYLFLGNLAFVDTWLSSTVTPNMLVNFFAKSKMISFSECVVQFFSFAICVTTECFLLATMAYDRYVAICKPLLYPVIMTNRLCMWLLVLSFLGGLFHATFHNAFLFRLTFCDSIIIHHFYCDIIPLFKISCTDPSINYLMVFIFAGIIQAFTISVVLVSYTFVFFTVLKKRSLQGIRKAFSTCGAHLLSVSLYYGPLLFMYVLPGSAQENDGDMMDSLFYTVIIPFLNSIIYSLRNKKVIDSLTKMLKRNV", "length": 309, "header": "tr|A0A5G2R433-1|A0A5G2R433_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100621954 PE=3 SV=1 CANONICAL=A0A5G2R433-1" }, "locus": { "chromosome": "13", "start_pos": 161177802, "end_pos": 161176876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102698.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102698.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076366.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076366.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R433", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621954", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621954", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GHE6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5h25b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "IGMEKTTLLIQFVLTGLVHLPQWKIPLFLLFLVIYLITVVGNLGLITLIWNDPHLHIPMYLFLASLAFVDTWLSSTVTPKMLQDIFAKSKLISFSECVTQFFSFVMSATTECFLLAAMAYDRYVAICKPLLYPVIMTNRLCVRLLTLSLVGGFIHALIHGGFLFRLIFCNSNIIYHFYCDVMPLLKISCNDPSLNYLMIFIFSGSIQVFTITTILVSYTLVLFSVLKQKSIKSIKKAVSTCGAHLLFVSLYYGPLLFMYVRPAPPQVGDQDMMDSVFYTIIIPVLNPIIYSLRNKQVKKSLAKFLKRHT", "length": 309 }, "evidence": [ { "id": "A0A5G2R433", "url": "https://omabrowser.org/oma/group/A0A5G2R433/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R433", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R433", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R433", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R433", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R433-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R433-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R433" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R433" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R476-1", "uniprot_ac": "A0A5G2R476", "uniprot_id": "A0A5G2R476_PIG", "mass": { "chemical_mass": 28326.0, "monoisotopic_mass": 28326.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110258961", "type": "recommended", "evidence": [ { "id": "A0A5G2R476", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R476", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R476", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R476", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110258961", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476", "locus": {} } ], "crossref": [ { "id": "A0A5G2R476", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R476", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000047557", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000047557", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R476", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R476-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYFFLRHLALTGISFSTVTVPKMLMNMQTQNPPITYPVCPSQVYFYMIFGCVDNLLLMVMTYDRYIAIYHPLHYTSVMRGGLCVLLVSGSWILSCSSALPNTLLLGQASFCADSIIPHFSCSLPKLLELSCSDTSLNELVIFTEESAVVIFPLSGILVSYGHIGLSILRVPSTKRICKALSTCGSHLSVVSLFYGTMMAVYFSSSSGQSHNKDIIASMMYTVVIPMLNPFIYSLRNRDMKLALGILFRNSNLLDK", "length": 255, "header": "tr|A0A5G2R476-1|A0A5G2R476_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258961 PE=3 SV=1 CANONICAL=A0A5G2R476-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R476-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476/entry#A0A5G2R476-1", "sequence": { "sequence": "MYFFLRHLALTGISFSTVTVPKMLMNMQTQNPPITYPVCPSQVYFYMIFGCVDNLLLMVMTYDRYIAIYHPLHYTSVMRGGLCVLLVSGSWILSCSSALPNTLLLGQASFCADSIIPHFSCSLPKLLELSCSDTSLNELVIFTEESAVVIFPLSGILVSYGHIGLSILRVPSTKRICKALSTCGSHLSVVSLFYGTMMAVYFSSSSGQSHNKDIIASMMYTVVIPMLNPFIYSLRNRDMKLALGILFRNSNLLDK", "length": 255, "header": "tr|A0A5G2R476-1|A0A5G2R476_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258961 PE=3 SV=1 CANONICAL=A0A5G2R476-1" }, "locus": { "chromosome": "AEMK02000598.1", "start_pos": 1670906, "end_pos": 1670142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106528.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106528.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076169.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076169.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R476", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R476", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R476", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R476", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R476", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R476-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 255, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R476-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R476" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R476", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R476" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 232, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R4C6-1", "uniprot_ac": "A0A5G2R4C6", "uniprot_id": "A0A5G2R4C6_PIG", "mass": { "chemical_mass": 34821.0, "monoisotopic_mass": 34821.0 }, "refseq": {}, "gene_names": [ { "name": "OR2S2", "type": "recommended", "evidence": [ { "id": "A0A5G2R4C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R4C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4C6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4C6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4C6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OR2S2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6", "locus": { "chromosome": "1", "start_pos": 236709673, "end_pos": 236710632, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000052192", "url": "https://www.ensembl.org/id/ENSSSCG00000052192" } ] } } ], "crossref": [ { "id": "A0A5G2R4C6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4C6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000048280", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000048280", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15430", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15430", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SQKCFRR", "url": "https://omabrowser.org/oma/group/SQKCFRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R4C6", "url": "https://www.orthodb.org/?gene=A0A5G2R4C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R4C6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKANQTSPVVGFILLGLSAHPKLEKMFFVLILLMYLVILLGNGLLILVTILDSRLHTPMYFFLGNLSFLDICYTTSSVPLVLDGFLTPRKTISFSGCAIQMFLSFAMAGTECVLLGMMAFDRYVAICNPLRYPVVMSKAAYVPMAVSSWAVGGVASLVHTSLAIQLPFCGDNIINHFACEILAVLKVACADISINVISMAVTNVIFLGVPVLFISVSYVFIIATILRIPSAEGRKKAFSTCSAHLTVVVIFYGTLFFMYGKPKSKDPLGADKEDLADKLIPLFYGVVTPMLNPIIYSLRNKDVKAAVKNLVAQKHSSH", "length": 319, "header": "tr|A0A5G2R4C6-1|A0A5G2R4C6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR2S2 PE=3 SV=1 CANONICAL=A0A5G2R4C6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R4C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6/entry#A0A5G2R4C6-1", "sequence": { "sequence": "MEKANQTSPVVGFILLGLSAHPKLEKMFFVLILLMYLVILLGNGLLILVTILDSRLHTPMYFFLGNLSFLDICYTTSSVPLVLDGFLTPRKTISFSGCAIQMFLSFAMAGTECVLLGMMAFDRYVAICNPLRYPVVMSKAAYVPMAVSSWAVGGVASLVHTSLAIQLPFCGDNIINHFACEILAVLKVACADISINVISMAVTNVIFLGVPVLFISVSYVFIIATILRIPSAEGRKKAFSTCSAHLTVVVIFYGTLFFMYGKPKSKDPLGADKEDLADKLIPLFYGVVTPMLNPIIYSLRNKDVKAAVKNLVAQKHSSH", "length": 319, "header": "tr|A0A5G2R4C6-1|A0A5G2R4C6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR2S2 PE=3 SV=1 CANONICAL=A0A5G2R4C6-1" }, "locus": { "chromosome": "1", "start_pos": 236710632, "end_pos": 236709676, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089206.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089206.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072063.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072063.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4C6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "M0QW35-1", "protein_name": "Olfactory receptor", "gene_name": "OR13C11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKPNQTSPLVGFILLGLSAHPKLEKTFFVLILLMYLVILLGNGVLILVTILDSRLHMPMYFFLENLSFLDICYTTSSVPLVLDSFLTPQKTISFSACAMQMFLSFSMAGTECVLLSMMAFDRYVAICNPLRYSVVMSKAVYVPMAAGSWAIGGVASLVHTSLVIQLPFCGANIINHFTCEILAVLKLACADISISVISMEVTNVIFLGVPVLFISVSYVFIIATILRIPSAEGKKKAFSTCSAHLTVVIIFYGTLFFMYGKPKSKDSQGADKEDLADKLIPLFYGVVIPMLNPIIYSLRNNDVKAAVRNLVSQKCFRR", "length": 319 }, "evidence": [ { "id": "A0A5G2R4C6", "url": "https://omabrowser.org/oma/group/A0A5G2R4C6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9NQN1-1", "protein_name": "Olfactory receptor 2S2", "gene_name": "OR2S2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKANETSPVMGFVLLRLSAHPELEKTFFVLILLMYLVILLGNGVLILVTILDSRLHTPMYFFLGNLSFLDICFTTSSVPLVLDSFLTPQETISFSACAVQMALSFAMAGTECLLLSMMAFDRYVAICNPLRYSVIMSKAAYMPMAASSWAIGGAASVVHTSLAIQLPFCGDNVINHFTCEILAVLKLACADISINVISMEVTNVIFLGVPVLFISFSYVFIITTILRIPSAEGRKKVFSTCSAHLTVVIVFYGTLFFMYGKPKSKDSMGADKEDLSDKLIPLFYGVVTPMLNPIIYSLRNKDVKAAVRRLLRPKGFTQ", "length": 319 }, "evidence": [ { "id": "A0A5G2R4C6", "url": "https://omabrowser.org/oma/group/A0A5G2R4C6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4C6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4C6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4C6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4C6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4C6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R4C6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 319, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R4C6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4C6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R4C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4C6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 297, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R4D9-1", "uniprot_ac": "A0A5G2R4D9", "uniprot_id": "A0A5G2R4D9_PIG", "mass": { "chemical_mass": 26785.0, "monoisotopic_mass": 26785.0 }, "refseq": {}, "gene_names": [ { "name": "LOC106510200", "type": "recommended", "evidence": [ { "id": "A0A5G2R4D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9" } ] } ], "protein_names": [ { "name": "Glutathione S-transferase", "type": "recommended", "evidence": [ { "id": "A0A5G2R4D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.18", "type": "synonym", "evidence": [ { "id": "A0A5G2R4D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4D9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC106510200", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9", "locus": {} } ], "crossref": [ { "id": "A0A5G2R4D9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4D9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000037808", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037808", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03075", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03075", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03209", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03209", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571:SF137", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571:SF137", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00043", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00043", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156590", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9026762", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9026762", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "16437", "url": "https://www.rhea-db.org/rhea/16437", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R4D9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLSDKFKLGLDFPNLPYLIDGAHKLTQSNAILRYIARKHNMCGETEEEKIRVDILENQAMDVRLQMARICYSPDFEKLKPGYLKEIPEILKCFSEFLGKRPWFAGDKVRGRLWGPGVLTYVDFLAYDVLDRNRIFEPKCLDEFPNLKDFITRFEGLKKISAYMKSSRFHPNPMFLKIAVWGNK", "length": 228, "header": "tr|A0A5G2R4D9-1|A0A5G2R4D9_PIG Isoform 1 of Glutathione S-transferase OS=Sus scrofa OX=9823 GN=LOC106510200 PE=1 SV=2 CANONICAL=A0A5G2R4D9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R4D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9/entry#A0A5G2R4D9-1", "sequence": { "sequence": "MTMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLSDKFKLGLDFPNLPYLIDGAHKLTQSNAILRYIARKHNMCGETEEEKIRVDILENQAMDVRLQMARICYSPDFEKLKPGYLKEIPEILKCFSEFLGKRPWFAGDKVRGRLWGPGVLTYVDFLAYDVLDRNRIFEPKCLDEFPNLKDFITRFEGLKKISAYMKSSRFHPNPMFLKIAVWGNK", "length": 228, "header": "tr|A0A5G2R4D9-1|A0A5G2R4D9_PIG Isoform 1 of Glutathione S-transferase OS=Sus scrofa OX=9823 GN=LOC106510200 PE=1 SV=2 CANONICAL=A0A5G2R4D9-1" }, "locus": { "chromosome": "4", "start_pos": 110413359, "end_pos": 110378919, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086895.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086895.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071951.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071951.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4D9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156590", "resource": "Reactome", "description": "Glutathione conjugation" }, { "id": "R-SSC-9026762", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9026762", "resource": "Reactome", "description": "Biosynthesis of maresin conjugates in tissue regeneration (MCTR)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4D9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4D9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4D9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4D9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16437", "name": "", "equation": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16437", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16437" } ] }, { "id": "R-SSC-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-176054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176054" } ] }, { "id": "R-SSC-9026777", "name": "GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9026777", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9026777" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R4D9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 228, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R4D9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4D9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R4D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9" }, { "id": "PS50405", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50405" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST C-terminal", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 219, "start_aa": "Thr", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R4D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4D9" }, { "id": "PS50404", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50404" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 88, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R4H0-1", "uniprot_ac": "A0A5G2R4H0", "uniprot_id": "A0A5G2R4H0_PIG", "mass": { "chemical_mass": 63553.0, "monoisotopic_mass": 63553.0 }, "refseq": { "ac": "XP_020928047", "name": "myotubularin-related protein 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928047" }, "gene_names": [ { "name": "MTMR9", "type": "recommended", "evidence": [ { "id": "A0A5G2R4H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ] }, { "name": "MTMR9", "type": "synonym", "evidence": [ { "id": "XP_020928047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928047" } ] } ], "protein_names": [ { "name": "Myotubularin-related protein 9", "type": "recommended", "evidence": [ { "id": "A0A5G2R4H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0/entry#names_and_taxonomy" } ] }, { "name": "Inactive phosphatidylinositol 3-phosphatase 9", "type": "synonym", "evidence": [ { "id": "A0A5G2R4H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0/entry#names_and_taxonomy" } ] }, { "name": "myotubularin-related protein 9", "type": "synonym", "evidence": [ { "id": "XP_020928047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928047" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MTMR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0", "locus": { "chromosome": "14", "start_pos": 14504449, "end_pos": 14458042, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000035133", "url": "https://www.ensembl.org/id/ENSSSCG00000035133" } ] } } ], "crossref": [ { "id": "ENSSSCG00000035133", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035133", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13211", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13211", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14536", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14536", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626566", "url": "https://www.ncbi.nlm.nih.gov/gene/100626566", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626566", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626566", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IEREWIC", "url": "https://omabrowser.org/oma/group/IEREWIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R4H0", "url": "https://www.orthodb.org/?gene=A0A5G2R4H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020928047", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928047", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1K407", "url": "https://www.uniprot.org/uniprotkb/A0A8D1K407", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1K407-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1K407-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGPLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMFEVIEDGWHSFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVIVPKAIDDEALRKVAMFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYIIDTRPLNVAQQARAKGGGFEQEAHYPQWRRIHKSIERYHILQDSLIKLVEACNDQTHNMDRWLSKLEASNWLTHIKEILTTACLAAQCLDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNSRQKWESPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNRPSELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELETEDGMQESP", "length": 549, "header": "tr|A0A5G2R4H0-1|A0A5G2R4H0_PIG Isoform 1 of Myotubularin-related protein 9 OS=Sus scrofa OX=9823 GN=MTMR9 PE=3 SV=1 CANONICAL=A0A5G2R4H0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R4H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0/entry#A0A5G2R4H0-1", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGPLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMFEVIEDGWHSFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVIVPKAIDDEALRKVAMFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYIIDTRPLNVAQQARAKGGGFEQEAHYPQWRRIHKSIERYHILQDSLIKLVEACNDQTHNMDRWLSKLEASNWLTHIKEILTTACLAAQCLDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNSRQKWESPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNRPSELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELETEDGMQESP", "length": 549, "header": "tr|A0A5G2R4H0-1|A0A5G2R4H0_PIG Isoform 1 of Myotubularin-related protein 9 OS=Sus scrofa OX=9823 GN=MTMR9 PE=3 SV=1 CANONICAL=A0A5G2R4H0-1" }, "locus": { "chromosome": "14", "start_pos": 14499683, "end_pos": 14458437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070625.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070625.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065457.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065457.1" } ] } }, { "isoform_ac": "A0A8D1K407-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0/entry#A0A8D1K407-1", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGPLGTIIIKCKDFRIIQLDIPGMEECLNIASSIETSEWRLSYVNKEFAVCPSYPPIVIVPKAIDDEALRKVAMFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYIIDTRPLNVAQQARAKGGGFEQEAHYPQWRRIHKSIERYHILQDSLIKLVEACNDQTHNMDRWLSKLEASNWLTHIKEILTTACLAAQCLDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNSRQKWESPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNRPSELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELETEDGMQESP", "length": 507, "header": "tr|A0A8D1K407-1|A0A5G2R4H0_PIG Computationally mapped isoform of Myotubularin-related protein 9 OS=Sus scrofa OX=9823 GN=MTMR9 PE=3 SV=1 CANONICAL=A0A5G2R4H0-1" }, "locus": { "chromosome": "14", "start_pos": 14499683, "end_pos": 14458437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039195.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039195.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033944.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033944.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1K407", "url": "https://www.uniprot.org/uniprotkb/A0A8D1K407" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626566", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626566", "resource": "KEGG Pathway" }, { "id": "R-SSC-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7GQU3-1", "protein_name": "Myotubularin-related protein 9", "gene_name": "Mtmr9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYPFFYRPMFEVIEDGWHSFLPEQEFELYSSATSEWRLSYINKEFTVCPSYPPTVIVPKSIDDEALRKVAAFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYLIDTRSLNVAQQARAKGGGFEQEAHYPQWRRIHKSIERYHVLQESLIKLVEACNEQTHNMDRWLGKLEASNWLTHIKEILTTACLAAQCIDREGASVLIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNSKQKWEAPVFLLFLDCVWQILRQFPCSFEFNEHFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNRPSELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWSRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELETEDGLRESP", "length": 549 }, "evidence": [ { "id": "A0A5G2R4H0", "url": "https://omabrowser.org/oma/group/A0A5G2R4H0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A7MB43-1", "protein_name": "Myotubularin-related protein 9", "gene_name": "MTMR9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGPLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMFEVIEDGWHSFLPEQEFELYSSTISEWRLSYVNKEFSVCPSYPPAVIVPKAIDDDALRKVATFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYIIDTRPLNIAQQARAKGGGFEQEAHYPQWRRIHKSIDRYHILQESLIKLVESCNDQTQNMDRWLSKLEASNWLTHIKEILTTACLAAQCLDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNSKQKWESPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNRPSELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNLLRRQLAELETEDGVQESP", "length": 549 }, "evidence": [ { "id": "A0A5G2R4H0", "url": "https://omabrowser.org/oma/group/A0A5G2R4H0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NFM3-1", "protein_name": "Myotubularin-related protein 9", "gene_name": "MTMR9", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEFAELIKTPRADNVVLHRPFEPAVEGTLCLTGHHLIFSSRRQDNAEELWLLHSNIDSIEKRFVGSLGTIVIKCKDLRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYPFFYRPMFEIVEDGWSAFLPEKEFEFLNALTDEWRLTYINKDFSICPSYPPVVTVPKSIDDETLQKVAVFRHGGRFPVLSYYHKKNGMVMMRTSQPLTGTNGKRCKDDEKLINSTLGPGRRGYIIDTRSLSAAQQARAKGGGFEVEVYYPQWRRIHKSVERFNILQESLIKLVEACNDQSHNMDRWLSKLEASNWLTHVKEILTAGCLAAQCIDREDASVLVHGTEGTDSTLQITSLAQIILDPDCRTIRGFESLIVREWLQAGHPFQQRCAQSAYSNSKQKWEAPVFLLFLDCVWQMLHQFPCSFEFNEHFLVTLFEHAYASQFGTFLGNNENERSKLKLPQKTMSLWSWVNQPEELKNFKNPLFEANSLVIWPSVAPQSLQLWEGVFLRWNRPSKFLDEAQEEMRKIISDNRVLQEKVNYLRRKVAHMETNDEMQEDL", "length": 550 }, "evidence": [ { "id": "A0A5G2R4H0", "url": "https://omabrowser.org/oma/group/A0A5G2R4H0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q96QG7-1", "protein_name": "Myotubularin-related protein 9", "gene_name": "MTMR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMFEVIEDGWHSFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALRKVATFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYIIDTRSLNVAQQTRAKGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEACNDQTHNMDRWLSKLEASNWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNQPSELSKFTNPLFEANNLVIWPSVAPQSLPLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELETEDGMQESP", "length": 549 }, "evidence": [ { "id": "A0A5G2R4H0", "url": "https://omabrowser.org/oma/group/A0A5G2R4H0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2D0-1", "protein_name": "Myotubularin-related protein 9", "gene_name": "Mtmr9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYTAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYPFFYRPMFEVIEDGWHSFLPEQEFEFYSSATSEWRLSYINKDFSICPSYPPTVIVPKSVDDEALRKVAAFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYLIDTRSLNVAQQARAKGGGFEQEAHYPQWRRIHKSIERYHVLQESLIKLVEACNEQTHNMDRWLGKLEASNWLTHIKEILTTACLAAQCIDREGASVLIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCSSKQKWEAPVFLLFLDCVWQILRQFPCSFEFNEHFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNRPGELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWSRSSKYLDEAYEEMVNIIEYNKELQAKVNVLRRQLAELETEDGL", "length": 545 }, "evidence": [ { "id": "A0A5G2R4H0", "url": "https://omabrowser.org/oma/group/A0A5G2R4H0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "pmid": "" }, { "name": "regulation of phosphatidylinositol dephosphorylation", "id": "GO:0060304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060304", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "pmid": "" }, { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4H0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R4H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4H0" }, { "id": "PS51339", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myotubularin phosphatase", "eco_id": "ECO_0000259", "start_pos": 123, "end_pos": 498, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 }, { "start_pos": 441, "end_pos": 443 }, { "start_pos": 502, "end_pos": 504 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R4I3-1", "uniprot_ac": "A0A5G2R4I3", "uniprot_id": "A0A5G2R4I3_PIG", "mass": { "chemical_mass": 175532.0, "monoisotopic_mass": 175532.0 }, "refseq": { "ac": "XP_005660237", "name": "spermatogenesis-associated protein 31D1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660237" }, "gene_names": [ { "name": "SPATA31D1", "type": "recommended", "evidence": [ { "id": "A0A5G2R4I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4I3" } ] }, { "name": "SPATA31D1", "type": "synonym", "evidence": [ { "id": "XP_005660237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660237" } ] } ], "protein_names": [ { "name": "SPATA31 subfamily D member 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R4I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4I3/entry#names_and_taxonomy" } ] }, { "name": "spermatogenesis-associated protein 31D1", "type": "synonym", "evidence": [ { "id": "XP_005660237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660237" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4I3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SPATA31D1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4I3", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000033805", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033805", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100154821", "url": "https://www.ncbi.nlm.nih.gov/gene/100154821", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154821", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154821", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R4I3", "url": "https://www.orthodb.org/?gene=A0A5G2R4I3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21859", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21859", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21859:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21859:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15371", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15371", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005660237", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660237", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R4I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4I3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWRDCPSKEPPKRECLRDKPGHPSVPANPRPLLTYQPDQSMCIAIRKIKRRVTQPSPAQITDFHTDPCLSFGSTSLDIDPNLTVVCGLGLLLLFLWYLVGFPCLPTSCKTKDIRKRQGRAKRRRKGGTSKGWRCRQTETEEKMKLISILKSPLGRHDDTTRFRQLLCPDPSCEVCNNASAEVSWLLFPEALEDATSSVSPLASTAPVTDSSFTLSPDASAVPPGDLIPASLSEPSPLPPSILSPRPMTPLVDFFLPSPLGHSLSPEPFAPLDSEFPVDCSPPQALAFPPLLPHDTQTADPVVPPEATLSLNTIFSLDPTFAQDINNLSDLSQAMNPIDSFACHHAPPTLCVSPQQDCTLTVTQSKSIAILLKPLPESTPPDSPGALSTYVPTLRGIDHSGLSVSDFSWWKAHAKDLFPPTLTQCDFNQEFLALHSAETSFGGDPAAIFVEPGNLSFLSPDVLALLERQVQKRSDFLMWKEKEKKKDYFPKQFGPDYQLNSSEKMMESNADKRDPAASLPFWSSKDKPKELHMHQQPPYPKSLEDHLQQKCIQLFWGLPSLHSESLPSAFHVSGDGSSVFIFNRNSNFSADQESPVHPHPLPLSLPEIQPEPLPQTLPPSQPLPLTEVQPQVHPQSPLPVIPSSPLSQIRICGVCFHKPQNEPECLTSSEIQQLEWNMLQKQQENLWGVPSVVQRSKEDSCLPAPSISYHQVPRGPGAPRAHASISIPPGEFPLSDEIRKKLEHHLRKRLIQHRWGLPRRITESVSLLMPPREFLEISEAESNYGVSLISVLKGQSSKNLSVGLSQPGSIHERDSEMLQQEADVGKDQGQSLEHHPKDHLLNDTKSSSDKDLEYDSEKDLNSQMPSLSEENLRVSAGSLGQRQLENALKVHLSKKFEEINEGKLPGTVNSSWHAIKQTLLILEKSHTQIEERNLPSSMGESYSLNTCHELTFVDSRAQQMLEAHIKKFHMRMLWGLPRKVLESIEIFKLKDASSQSLSHSNFSSSTNELSEADSKSGSIRFQRGSSKSLHGDKVGTTASAPATRPVGKGGQRILRRSHPNTNRGLAEDVQRSKDARQTRPTSKLCISGKANQRQMHPANRYPSKLLTKQAGARQEPKSKSVSSRDKGEMKQGQKVEKLEPVSMPNVSREIFRAEELNAVQLKASENLTTSKPGSSQAINVNENKVETTVTTERPPRKLPVPQDPKSLDLKEQLLDELKCKLENRGHSQAQGRPLDASLAPDNLTYKASLTHAQGVSGGDMGASQVLHAHLEDRGIRMEQQQKTWVPKNGFRRCQDNNFPCTAKRVSSPGPKAEELGGGDAGLGTSQLRRKSLPTQKMVLEETLGSKSCQTLSQKGQPPPESLTRKRMKHFFQWLYPGGKCKRQEGPQEKGSPVSAAQIRGLVKSRATVTGTTEAQKIMTDIGKFLEEKLVCQHPVDVPCSQESLPSPEKSGKTQQKAEVQVQTGPGQGHPLNYRVPVSKVTNNKSCHQEAIFPGQSYPPSTRKIRDKNINPHRVVACKGQQLCQKHPPPVPCREHVPHPSPTCRHQAVQAPLATLSTAKGTVFRDLSLLFRQKSLLQSFQGGKGPIQK", "length": 1587, "header": "tr|A0A5G2R4I3-1|A0A5G2R4I3_PIG Isoform 1 of SPATA31 subfamily D member 1 OS=Sus scrofa OX=9823 GN=SPATA31D1 PE=3 SV=1 CANONICAL=A0A5G2R4I3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R4I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4I3/entry#A0A5G2R4I3-1", "sequence": { "sequence": "MWRDCPSKEPPKRECLRDKPGHPSVPANPRPLLTYQPDQSMCIAIRKIKRRVTQPSPAQITDFHTDPCLSFGSTSLDIDPNLTVVCGLGLLLLFLWYLVGFPCLPTSCKTKDIRKRQGRAKRRRKGGTSKGWRCRQTETEEKMKLISILKSPLGRHDDTTRFRQLLCPDPSCEVCNNASAEVSWLLFPEALEDATSSVSPLASTAPVTDSSFTLSPDASAVPPGDLIPASLSEPSPLPPSILSPRPMTPLVDFFLPSPLGHSLSPEPFAPLDSEFPVDCSPPQALAFPPLLPHDTQTADPVVPPEATLSLNTIFSLDPTFAQDINNLSDLSQAMNPIDSFACHHAPPTLCVSPQQDCTLTVTQSKSIAILLKPLPESTPPDSPGALSTYVPTLRGIDHSGLSVSDFSWWKAHAKDLFPPTLTQCDFNQEFLALHSAETSFGGDPAAIFVEPGNLSFLSPDVLALLERQVQKRSDFLMWKEKEKKKDYFPKQFGPDYQLNSSEKMMESNADKRDPAASLPFWSSKDKPKELHMHQQPPYPKSLEDHLQQKCIQLFWGLPSLHSESLPSAFHVSGDGSSVFIFNRNSNFSADQESPVHPHPLPLSLPEIQPEPLPQTLPPSQPLPLTEVQPQVHPQSPLPVIPSSPLSQIRICGVCFHKPQNEPECLTSSEIQQLEWNMLQKQQENLWGVPSVVQRSKEDSCLPAPSISYHQVPRGPGAPRAHASISIPPGEFPLSDEIRKKLEHHLRKRLIQHRWGLPRRITESVSLLMPPREFLEISEAESNYGVSLISVLKGQSSKNLSVGLSQPGSIHERDSEMLQQEADVGKDQGQSLEHHPKDHLLNDTKSSSDKDLEYDSEKDLNSQMPSLSEENLRVSAGSLGQRQLENALKVHLSKKFEEINEGKLPGTVNSSWHAIKQTLLILEKSHTQIEERNLPSSMGESYSLNTCHELTFVDSRAQQMLEAHIKKFHMRMLWGLPRKVLESIEIFKLKDASSQSLSHSNFSSSTNELSEADSKSGSIRFQRGSSKSLHGDKVGTTASAPATRPVGKGGQRILRRSHPNTNRGLAEDVQRSKDARQTRPTSKLCISGKANQRQMHPANRYPSKLLTKQAGARQEPKSKSVSSRDKGEMKQGQKVEKLEPVSMPNVSREIFRAEELNAVQLKASENLTTSKPGSSQAINVNENKVETTVTTERPPRKLPVPQDPKSLDLKEQLLDELKCKLENRGHSQAQGRPLDASLAPDNLTYKASLTHAQGVSGGDMGASQVLHAHLEDRGIRMEQQQKTWVPKNGFRRCQDNNFPCTAKRVSSPGPKAEELGGGDAGLGTSQLRRKSLPTQKMVLEETLGSKSCQTLSQKGQPPPESLTRKRMKHFFQWLYPGGKCKRQEGPQEKGSPVSAAQIRGLVKSRATVTGTTEAQKIMTDIGKFLEEKLVCQHPVDVPCSQESLPSPEKSGKTQQKAEVQVQTGPGQGHPLNYRVPVSKVTNNKSCHQEAIFPGQSYPPSTRKIRDKNINPHRVVACKGQQLCQKHPPPVPCREHVPHPSPTCRHQAVQAPLATLSTAKGTVFRDLSLLFRQKSLLQSFQGGKGPIQK", "length": 1587, "header": "tr|A0A5G2R4I3-1|A0A5G2R4I3_PIG Isoform 1 of SPATA31 subfamily D member 1 OS=Sus scrofa OX=9823 GN=SPATA31D1 PE=3 SV=1 CANONICAL=A0A5G2R4I3-1" }, "locus": { "chromosome": "1", "start_pos": 234562182, "end_pos": 234546787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070735.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070735.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071996.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071996.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4I3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154821", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154821", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4I3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4I3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1000, "end_pos": 1002, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1144, "end_pos": 1146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1165, "end_pos": 1167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1241, "end_pos": 1243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1482, "end_pos": 1484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 798, "end_pos": 800, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" }, { "start_pos": 841, "end_pos": 843, "annotation": "n_glycosylation_sequon" }, { "start_pos": 908, "end_pos": 910, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R4I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4I3" }, { "id": "PF14650", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14650" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SPATA31", "eco_id": "ECO_0000259", "start_pos": 534, "end_pos": 911, "start_aa": "Gln", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R4I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4I3" }, { "id": "PF15371", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15371" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SPATA31-like", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 206, "start_aa": "Arg", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1000, "end_pos": 1002 }, { "start_pos": 1144, "end_pos": 1146 }, { "start_pos": 1165, "end_pos": 1167 }, { "start_pos": 1241, "end_pos": 1243 }, { "start_pos": 1482, "end_pos": 1484 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 586, "end_pos": 588 }, { "start_pos": 798, "end_pos": 800 }, { "start_pos": 81, "end_pos": 83 }, { "start_pos": 841, "end_pos": 843 }, { "start_pos": 908, "end_pos": 910 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R4R2-1", "uniprot_ac": "A0A5G2R4R2", "uniprot_id": "A0A5G2R4R2_PIG", "mass": { "chemical_mass": 34928.0, "monoisotopic_mass": 34928.0 }, "refseq": { "ac": "XP_003355173", "name": "olfactory receptor 10K1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355173" }, "gene_names": [ { "name": "LOC100627086", "type": "recommended", "evidence": [ { "id": "A0A5G2R4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2" } ] }, { "name": "LOC100627086", "type": "synonym", "evidence": [ { "id": "XP_003355173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355173" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 10K1-like", "type": "synonym", "evidence": [ { "id": "XP_003355173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355173" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100627086", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2", "locus": {} } ], "crossref": [ { "id": "A0A5G2R4R2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4R2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100627086", "url": "https://www.ncbi.nlm.nih.gov/gene/100627086", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100627086", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627086", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SCCETCY", "url": "https://omabrowser.org/oma/group/SCCETCY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R4R2", "url": "https://www.orthodb.org/?gene=A0A5G2R4R2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003355173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355173", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R4R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEWVNETTVRQFVFLGFSSLAGLQKLLFVVFLLVYLFTLGTNAIIISTIVLDRALHTPMYFFLGVLSCSETCYTFVIVPKMLVDLLAQKKTISFRGCAIQMFSFLFLICSHSFLLAAMGYDRYVAICNPLRYTVLMGYGVCVGLVAAACACGFIISLVTTSMIFHLPFHSSNQLHHFFCDVSPVLKLASHHSHLIQLVIFVLGVFVLVIPLLLILVSYVLIISAILKIPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDTLISVSYTILTPLLNPMIYSLRNKEFKSALRKAMVQTSYPTN", "length": 313, "header": "tr|A0A5G2R4R2-1|A0A5G2R4R2_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100627086 PE=3 SV=1 CANONICAL=A0A5G2R4R2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R4R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2/entry#A0A5G2R4R2-1", "sequence": { "sequence": "MEWVNETTVRQFVFLGFSSLAGLQKLLFVVFLLVYLFTLGTNAIIISTIVLDRALHTPMYFFLGVLSCSETCYTFVIVPKMLVDLLAQKKTISFRGCAIQMFSFLFLICSHSFLLAAMGYDRYVAICNPLRYTVLMGYGVCVGLVAAACACGFIISLVTTSMIFHLPFHSSNQLHHFFCDVSPVLKLASHHSHLIQLVIFVLGVFVLVIPLLLILVSYVLIISAILKIPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDTLISVSYTILTPLLNPMIYSLRNKEFKSALRKAMVQTSYPTN", "length": 313, "header": "tr|A0A5G2R4R2-1|A0A5G2R4R2_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100627086 PE=3 SV=1 CANONICAL=A0A5G2R4R2-1" }, "locus": { "chromosome": "4", "start_pos": 91950977, "end_pos": 91950039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090040.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090040.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069175.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069175.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100627086", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627086", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R4R2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R4R2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4R2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4R2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Thr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R4S7-1", "uniprot_ac": "A0A5G2R4S7", "uniprot_id": "A0A5G2R4S7_PIG", "mass": { "chemical_mass": 34657.0, "monoisotopic_mass": 34657.0 }, "refseq": {}, "gene_names": [ { "name": "OR4B1", "type": "recommended", "evidence": [ { "id": "A0A5G2R4S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R4S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OR4B1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7", "locus": { "chromosome": "2", "start_pos": 14510944, "end_pos": 14511873, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000053706", "url": "https://www.ensembl.org/id/ENSSSCG00000053706" } ] } } ], "crossref": [ { "id": "A0A5G2R4S7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4S7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041772", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041772", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523717", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523717", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QLCHILV", "url": "https://omabrowser.org/oma/group/QLCHILV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R4S7", "url": "https://www.orthodb.org/?gene=A0A5G2R4S7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R4S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASTKNVTELIFTGLFEDPEVQRVCFVVFLPVYLATVVGNGLIVLTVKVSQNLHSPMYFFLSYLSLVEISYSSTVAPKFIADLLSKVKTISLEGCVAQIFFFHFFGVAEIFLLVVMAYDRYVAICKPLHYMNIMSHQLCHRLVAGSFLGGFVHSIIQILITIQLPFCGPNVIDHYFCDLQPLFKLACTDTSVEGLIVLANSGLIALCSFLILVTSYIVILVNLRNHSAEGRRKAFSTCASHITVVLLFFGPAIFLYMRPSSTFTEDKLVAVFYTVVTPMLNPIIYTLRNAEVKIAMRRLWDKKENSGME", "length": 309, "header": "tr|A0A5G2R4S7-1|A0A5G2R4S7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR4B1 PE=3 SV=1 CANONICAL=A0A5G2R4S7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R4S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7/entry#A0A5G2R4S7-1", "sequence": { "sequence": "MASTKNVTELIFTGLFEDPEVQRVCFVVFLPVYLATVVGNGLIVLTVKVSQNLHSPMYFFLSYLSLVEISYSSTVAPKFIADLLSKVKTISLEGCVAQIFFFHFFGVAEIFLLVVMAYDRYVAICKPLHYMNIMSHQLCHRLVAGSFLGGFVHSIIQILITIQLPFCGPNVIDHYFCDLQPLFKLACTDTSVEGLIVLANSGLIALCSFLILVTSYIVILVNLRNHSAEGRRKAFSTCASHITVVLLFFGPAIFLYMRPSSTFTEDKLVAVFYTVVTPMLNPIIYTLRNAEVKIAMRRLWDKKENSGME", "length": 309, "header": "tr|A0A5G2R4S7-1|A0A5G2R4S7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR4B1 PE=3 SV=1 CANONICAL=A0A5G2R4S7-1" }, "locus": { "chromosome": "2", "start_pos": 14511873, "end_pos": 14510947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083413.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083413.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065568.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065568.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523717", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523717", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K6K2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARANNVTELIITGLFQDPNVQKVCFVLFLPVYMATVLGNGLIVAMVSVSKSLHSPMYIFLSSLSLVEIFYSSTVVPKFITDLLAKVKTISLNGCLAQIFFFHFLGVAEIFLLVVMAYDRYVAICKPLHYMNIMSRQVCHTLVAVSWLGGFLHSIIQVLITIQLPFCGPNVIDHYFCDLQPLFKLACTDTFVESVIVMANSGLIALCSFLVLVSSYVIILINLRNHSADGRHKALSTCASHITVVILFFGPAIFLYMRHSSTFTEDKLVAVFYTVITPMLNPIIYTLRNAEVKNAVRKLWGKKNIGIK", "length": 308 }, "evidence": [ { "id": "A0A5G2R4S7", "url": "https://omabrowser.org/oma/group/A0A5G2R4S7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NGF8-1", "protein_name": "Olfactory receptor 4B1", "gene_name": "OR4B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASTSNVTELIFTGLFQDPAVQSVCFVVFLPVYLATVVGNGLIVLTVSISKSLDSPMYFFLSCLSLVEISYSSTIAPKFIIDLLAKIKTISLEGCLTQIFFFHFFGVAEILLIVVMAYDCYVAICKPLHYMNIISRQLCHLLVAGSWLGGFCHSIIQILVIIQLPFCGPNVIDHYFCDLQPLFKLACTDTFMEGVIVLANSGLFSVFSFLILVSSYIVILVNLRNHSAEGRHKALSTCASHITVVILFFGPAIFLYMRPSSTFTEDKLVAVFYTVITPMLNPIIYTLRNAEVKIAIRRLWSKKENPGRE", "length": 309 }, "evidence": [ { "id": "A0A5G2R4S7", "url": "https://omabrowser.org/oma/group/A0A5G2R4S7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VGP3-1", "protein_name": "Olfactory receptor", "gene_name": "Or4b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARENNVTELIITGLFQDPNVQKVCFVLFLPVYLATVLGNGLIVAMVIVSKSLHSPMYIFLSSLSLVEICYSSTVVPKFITDLLAKVKTISLKGCLAQIFFFHFLGVAEIFLLVVMAYDRYVAICKPLHYMNIMSRQVCHVLVAVSWLGGFLHSIIQVLISIQLPFCGPNVIDHYFCDLQPLFKLACTDTFVESVIVMANSGLIALCSFLVLVSSYVIILVNLRKHSAEGRRKALSTCASHITVVVLFFGPAIFLYMRPSSTFTEDKLVAVFYTVITPMLNPIIYTLRNAEVKNAVRKLWGKRI", "length": 304 }, "evidence": [ { "id": "A0A5G2R4S7", "url": "https://omabrowser.org/oma/group/A0A5G2R4S7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4S7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R4S7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R4S7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4S7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R4S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R4Y4-1", "uniprot_ac": "A0A5G2R4Y4", "uniprot_id": "A0A5G2R4Y4_PIG", "mass": { "chemical_mass": 35474.0, "monoisotopic_mass": 35474.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Vomeronasal type-1 receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R4Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative pheromone receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Y4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4#function" }, { "database": "UniProtKB", "id": "ARBA00003878", "url": "https://www.uniprot.org/uniprotkb/ARBA00003878#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Y4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4", "locus": {} } ], "crossref": [ { "id": "A0A5G2R4Y4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4Y4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000046174", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000046174", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13949", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13949", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24062", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24062", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R4Y4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "DNNNNLVLPSAFLSYRGWTPGEFLPFCHYIILYFTGYRSRSTDVILQHLIVANFLTLLSKGVPQTMAAFGCKLSPSDFGCKMIFFLHRVGRGVSMGSICLLSVFQVITISPQNSRWAELKAKAPQHIVPSMCLCWMLQMLVNVVFPVNITGKYSDKNITNRRDFGYCSALRYDETRSILLALLLLLPDVSCLGLMLWASGSMVFLLYRHKQQVQHIRRNIISPRSSPESRATRTILLLVSSFVSFYTLACTFQLVLALFGNPSWFLVKITIVMAAWFPTVSPFLLMSRDLTVHRIYVAWIRNAQSPTVRRNL", "length": 312, "header": "tr|A0A5G2R4Y4-1|A0A5G2R4Y4_PIG Isoform 1 of Vomeronasal type-1 receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R4Y4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R4Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4/entry#A0A5G2R4Y4-1", "sequence": { "sequence": "DNNNNLVLPSAFLSYRGWTPGEFLPFCHYIILYFTGYRSRSTDVILQHLIVANFLTLLSKGVPQTMAAFGCKLSPSDFGCKMIFFLHRVGRGVSMGSICLLSVFQVITISPQNSRWAELKAKAPQHIVPSMCLCWMLQMLVNVVFPVNITGKYSDKNITNRRDFGYCSALRYDETRSILLALLLLLPDVSCLGLMLWASGSMVFLLYRHKQQVQHIRRNIISPRSSPESRATRTILLLVSSFVSFYTLACTFQLVLALFGNPSWFLVKITIVMAAWFPTVSPFLLMSRDLTVHRIYVAWIRNAQSPTVRRNL", "length": 312, "header": "tr|A0A5G2R4Y4-1|A0A5G2R4Y4_PIG Isoform 1 of Vomeronasal type-1 receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R4Y4-1" }, "locus": { "chromosome": "6", "start_pos": 57527303, "end_pos": 57525525, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077214.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077214.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072141.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072141.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Y4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Y4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Y4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4" } ], "pmid": "" }, { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Y4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pheromone binding", "id": "GO:0005550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005550", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Y4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4" } ], "pmid": "" }, { "name": "pheromone receptor activity", "id": "GO:0016503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016503", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4Y4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R4Y4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R4Y4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R4Y4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R4Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Y4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 285, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 }, { "start_pos": 157, "end_pos": 159 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R591-1", "uniprot_ac": "A0A5G2R591", "uniprot_id": "A0A5G2R591_PIG", "mass": { "chemical_mass": 44770.0, "monoisotopic_mass": 44770.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R591/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R591", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R591" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R591", "locus": {} } ], "crossref": [ { "id": "A0A5G2R591", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R591", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000042484", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042484", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R591", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R591", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R591-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R591-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHAPTEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHLISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQAAAQPWFLTPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2R591-1|A0A5G2R591_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R591-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R591-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R591/entry#A0A5G2R591-1", "sequence": { "sequence": "MAHAPTEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHLISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQAAAQPWFLTPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2R591-1|A0A5G2R591_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R591-1" }, "locus": { "chromosome": "Y", "start_pos": 23852272, "end_pos": 23810534, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082890.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082890.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065744.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065744.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 356, "start_aa": "Thr", "end_pos": 356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr356", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R591", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R591" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R591", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R591" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R591", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R591" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R591", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R591" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R591-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R591-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R591" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R591" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 356 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2R5A1-1", "uniprot_ac": "A0A5G2R5A1", "uniprot_id": "A0A5G2R5A1_PIG", "mass": { "chemical_mass": 16765.0, "monoisotopic_mass": 16765.0 }, "refseq": { "ac": "XP_001927852", "name": "fucose mutarotase isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927852" }, "gene_names": [ { "name": "FUOM", "type": "recommended", "evidence": [ { "id": "A0A5G2R5A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1" } ] }, { "name": "FUOM", "type": "synonym", "evidence": [ { "id": "XP_001927852", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927852" } ] } ], "protein_names": [ { "name": "Fucose mutarotase", "type": "recommended", "evidence": [ { "id": "A0A5G2R5A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1/entry#names_and_taxonomy" } ] }, { "name": "5.1.3.29", "type": "synonym", "evidence": [ { "id": "A0A5G2R5A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1/entry#names_and_taxonomy" } ] }, { "name": "fucose mutarotase isoform X3", "type": "synonym", "evidence": [ { "id": "XP_001927852", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927852" } ] } ], "function": [ { "annotation": "Involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1#function" }, { "database": "UniProtKB", "id": "ARBA00058446", "url": "https://www.uniprot.org/uniprotkb/ARBA00058446#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FUOM", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1", "locus": { "chromosome": "14", "start_pos": 141331810, "end_pos": 141336633, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010791", "url": "https://www.ensembl.org/id/ENSSSCG00000010791" } ] } } ], "crossref": [ { "id": "A0A5G2R5A1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5A1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010791", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010791", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152128", "url": "https://www.ncbi.nlm.nih.gov/gene/100152128", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152128", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152128", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R5A1", "url": "https://www.orthodb.org/?gene=A0A5G2R5A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1SAC0", "url": "https://www.orthodb.org/?gene=F1SAC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31690:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31690:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6787639", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6787639", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001927852", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927852", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "25580", "url": "https://www.rhea-db.org/rhea/25580", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R5A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SAC0", "url": "https://www.uniprot.org/uniprotkb/F1SAC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SAC0-1", "url": "https://www.uniprot.org/uniprotkb/F1SAC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVALKGIPALLSPELLYALARMGHGDEIVLADVNFPTSSVCRCGPEEIRADGLGIPQLLEAVLTLLPLDTYVESPAAVMELVPSDRERGLQTPVWTSYQSILLQAGCTSSLTAIERFEFYERAKKAFAVVATGETALYGNLILKKGVLAPGALSQAC", "length": 157, "header": "tr|A0A5G2R5A1-1|A0A5G2R5A1_PIG Isoform 1 of Fucose mutarotase OS=Sus scrofa OX=9823 GN=FUOM PE=1 SV=1 CANONICAL=A0A5G2R5A1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R5A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1/entry#A0A5G2R5A1-1", "sequence": { "sequence": "MVALKGIPALLSPELLYALARMGHGDEIVLADVNFPTSSVCRCGPEEIRADGLGIPQLLEAVLTLLPLDTYVESPAAVMELVPSDRERGLQTPVWTSYQSILLQAGCTSSLTAIERFEFYERAKKAFAVVATGETALYGNLILKKGVLAPGALSQAC", "length": 157, "header": "tr|A0A5G2R5A1-1|A0A5G2R5A1_PIG Isoform 1 of Fucose mutarotase OS=Sus scrofa OX=9823 GN=FUOM PE=1 SV=1 CANONICAL=A0A5G2R5A1-1" }, "locus": { "chromosome": "14", "start_pos": 141336074, "end_pos": 141332799, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071629.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071629.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065754.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065754.1" } ] } }, { "isoform_ac": "F1SAC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1/entry#F1SAC0-1", "sequence": { "sequence": "MVALKGIPALLSPELLYALARMGHGDEIVLADVNFPTSSVCRCGPEEIRADGLGIPQLLEAVLTLLPLDTYVESPAAVMELVPSDRERGLQTPVWTSYQSILLQAGCTGDGPLRKPHPQEGGAGARRPVPGLLTVCPERSLDPGPDSTTSRQVQRPDEPALLCLSAREPHPARGSGASGFADWAGVVPVYENKGRAQ", "length": 197, "header": "tr|F1SAC0-1|F1SAC0_PIG Computationally mapped isoform of L-fucose mutarotase OS=Sus scrofa OX=9823 GN=FUOM PE=1 SV=3 CANONICAL=A0A5G2R5A1-1" }, "locus": { "chromosome": "14", "start_pos": 141336074, "end_pos": 141332605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011807.4", "url": "https://www.ensembl.org/id/ENSSSCT00000011807.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011504.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011504.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152128", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152128", "resource": "KEGG Pathway" }, { "id": "R-SSC-6787639", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6787639", "resource": "Reactome", "description": "GDP-fucose biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "monosaccharide metabolic process", "id": "GO:0005996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005996", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1" } ], "pmid": "" }, { "name": "fucose metabolic process", "id": "GO:0006004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006004", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "monosaccharide binding", "id": "GO:0048029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048029", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1" } ], "pmid": "" }, { "name": "L-fucose mutarotase activity", "id": "GO:0036373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036373", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1" } ], "pmid": "" }, { "name": "fucose binding", "id": "GO:0042806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042806", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1" } ], "pmid": "" }, { "name": "racemase and epimerase activity, acting on carbohydrates and derivatives", "id": "GO:0016857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016857", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5A1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25580", "name": "", "equation": "alpha-L-fucose = beta-L-fucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "25580", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25580" } ] }, { "id": "R-SSC-6787677", "name": "FUOM isomerises alpha-Fuc to beta-Fuc", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-6787679" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6787677", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6787677" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6787679", "participant_name": "alpha-Fuc [cytosol]", "crossref": [ { "id": "42548", "database": "ChEBI", "url": "" }, { "id": "G96881BQ", "database": "GlyTouCan", "url": "" }, { "id": "ZINC000001532814", "database": "ZINC", "url": "" }, { "id": "HMDB0000174", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R5A1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 157, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R5A1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5A1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R5D4-1", "uniprot_ac": "A0A5G2R5D4", "uniprot_id": "A0A5G2R5D4_PIG", "mass": { "chemical_mass": 35028.0, "monoisotopic_mass": 35028.0 }, "refseq": { "ac": "XP_005652897", "name": "olfactory receptor 7G2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652897" }, "gene_names": [ { "name": "LOC100515649", "type": "recommended", "evidence": [ { "id": "A0A5G2R5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4" } ] }, { "name": "LOC100515649", "type": "synonym", "evidence": [ { "id": "XP_005652897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652897" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7G2-like", "type": "synonym", "evidence": [ { "id": "XP_005652897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652897" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5D4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5D4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100515649", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4", "locus": {} } ], "crossref": [ { "id": "A0A5G2R5D4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5D4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515649", "url": "https://www.ncbi.nlm.nih.gov/gene/100515649", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515649", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515649", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVIPQVM", "url": "https://omabrowser.org/oma/group/IVIPQVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R5D4", "url": "https://www.orthodb.org/?gene=A0A5G2R5D4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005652897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652897", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R5D4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESKNQTDVSKFLLLGLTEDPELQPFLFFLFLSIYLVTVLGNLLIILAVSSDSHLYTPMYFFLSNLSFTEICLSTTTIPKMLVNIQTHNQSITYRGCLIQICFILLFGGFENFILAVMAYDRYVAICHPLRYMVIVNPQLCLLLVLPPLLMSTIVGLILSLTMLRLSFCKNLEIPHFFCELPQVIKLACSDTLINNILIYLAIGVFGAISLPGIIFSYIRIVSSVLRMPSARAKLKAFSTCGSHLSVVFLFCGTVFGVYISSEVTTSPRKTSVASVMYIVVPQMMNPFIYSLRNSDMKAALRKLIRKLSSFL", "length": 312, "header": "tr|A0A5G2R5D4-1|A0A5G2R5D4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100515649 PE=3 SV=1 CANONICAL=A0A5G2R5D4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R5D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4/entry#A0A5G2R5D4-1", "sequence": { "sequence": "MESKNQTDVSKFLLLGLTEDPELQPFLFFLFLSIYLVTVLGNLLIILAVSSDSHLYTPMYFFLSNLSFTEICLSTTTIPKMLVNIQTHNQSITYRGCLIQICFILLFGGFENFILAVMAYDRYVAICHPLRYMVIVNPQLCLLLVLPPLLMSTIVGLILSLTMLRLSFCKNLEIPHFFCELPQVIKLACSDTLINNILIYLAIGVFGAISLPGIIFSYIRIVSSVLRMPSARAKLKAFSTCGSHLSVVFLFCGTVFGVYISSEVTTSPRKTSVASVMYIVVPQMMNPFIYSLRNSDMKAALRKLIRKLSSFL", "length": 312, "header": "tr|A0A5G2R5D4-1|A0A5G2R5D4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100515649 PE=3 SV=1 CANONICAL=A0A5G2R5D4-1" }, "locus": { "chromosome": "2", "start_pos": 67157245, "end_pos": 67156310, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082810.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082810.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065794.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065794.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5D4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515649", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515649", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5D4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5D4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5D4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5D4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R5D4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R5D4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5D4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5D4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R5I5-1", "uniprot_ac": "A0A5G2R5I5", "uniprot_id": "A0A5G2R5I5_PIG", "mass": { "chemical_mass": 33821.0, "monoisotopic_mass": 33821.0 }, "refseq": { "ac": "XP_013834548", "name": "olfactory receptor 481-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834548" }, "gene_names": [ { "name": "LOC100621852", "type": "synonym", "evidence": [ { "id": "XP_013834548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834548" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R5I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 481-like", "type": "synonym", "evidence": [ { "id": "XP_013834548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834548" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5", "locus": {} } ], "crossref": [ { "id": "A0A5G2R5I5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5I5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100621852", "url": "https://www.ncbi.nlm.nih.gov/gene/100621852", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621852", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621852", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R5I5", "url": "https://www.orthodb.org/?gene=A0A5G2R5I5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013834548", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834548", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R5I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPANHTTVTEFVILGLTDNPTLCAIFFVVFLGVYIVTIVGNISIIILIRSSPQLHTPMYLFLRHLAFVDVGYSTSVTPVMLVSFLRETTAVPVPGCIAQLGSDVAFGTAECFLLAAMAYDRYVAIGSPLLYPARMSPGLCLRLLAASYLGGCANASSFTGCLLSLSFCGPNTINHFFCDLFPLLQLSCGHAYFAEISPAISSASVLASTLATITASYASVLRSILRMRSTEGRKKAFSTCTSHLTAVTLFYGTVLLVYVMPKSRYSADRVKVASVTYTVVVPMLNPLIYSLRNKEVREAVRKLTARTHCFA", "length": 312, "header": "tr|A0A5G2R5I5-1|A0A5G2R5I5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R5I5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R5I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5/entry#A0A5G2R5I5-1", "sequence": { "sequence": "MEPANHTTVTEFVILGLTDNPTLCAIFFVVFLGVYIVTIVGNISIIILIRSSPQLHTPMYLFLRHLAFVDVGYSTSVTPVMLVSFLRETTAVPVPGCIAQLGSDVAFGTAECFLLAAMAYDRYVAIGSPLLYPARMSPGLCLRLLAASYLGGCANASSFTGCLLSLSFCGPNTINHFFCDLFPLLQLSCGHAYFAEISPAISSASVLASTLATITASYASVLRSILRMRSTEGRKKAFSTCTSHLTAVTLFYGTVLLVYVMPKSRYSADRVKVASVTYTVVVPMLNPLIYSLRNKEVREAVRKLTARTHCFA", "length": 312, "header": "tr|A0A5G2R5I5-1|A0A5G2R5I5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R5I5-1" }, "locus": { "chromosome": "9", "start_pos": 1900695, "end_pos": 1899760, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086429.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086429.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071584.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071584.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621852", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621852", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R5I5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R5I5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5I5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R5I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R5J2-1", "uniprot_ac": "A0A5G2R5J2", "uniprot_id": "A0A5G2R5J2_PIG", "mass": { "chemical_mass": 43966.0, "monoisotopic_mass": 43966.0 }, "refseq": { "ac": "XP_001929096", "name": "G protein-activated inward rectifier potassium channel 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929096" }, "gene_names": [ { "name": "KCNJ9", "type": "recommended", "evidence": [ { "id": "A0A5G2R5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2" } ] }, { "name": "KCNJ9", "type": "synonym", "evidence": [ { "id": "XP_001929096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929096" } ] } ], "protein_names": [ { "name": "G protein-activated inward rectifier potassium channel 3", "type": "recommended", "evidence": [ { "id": "A0A5G2R5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2/entry#names_and_taxonomy" } ] }, { "name": "G protein-activated inward rectifier potassium channel 3", "type": "synonym", "evidence": [ { "id": "XP_001929096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929096" } ] }, { "name": "Inward rectifier K(+) channel Kir3.3", "type": "synonym", "evidence": [ { "id": "A0A5G2R5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2/entry#names_and_taxonomy" } ] }, { "name": "Potassium channel, inwardly rectifying subfamily J member 9", "type": "synonym", "evidence": [ { "id": "A0A5G2R5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KCNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2", "locus": { "chromosome": "4", "start_pos": 90397850, "end_pos": 90412373, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006393", "url": "https://www.ensembl.org/id/ENSSSCG00000006393" } ] } } ], "crossref": [ { "id": "A0A5G2R5J2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5J2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006393", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006393", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152828", "url": "https://www.ncbi.nlm.nih.gov/gene/100152828", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152828", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152828", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R5J2", "url": "https://www.orthodb.org/?gene=A0A5G2R5J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01007", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01007", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17655", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17655", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1296041", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296041", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-997272", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001929096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929096", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R5J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0QKJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8D0QKJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0QKJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0QKJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQENAAFSPGPEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSNAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGAGEGAGEGAGADKEQNGCLPPPESESKV", "length": 393, "header": "tr|A0A5G2R5J2-1|A0A5G2R5J2_PIG Isoform 1 of G protein-activated inward rectifier potassium channel 3 OS=Sus scrofa OX=9823 GN=KCNJ9 PE=3 SV=1 CANONICAL=A0A5G2R5J2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R5J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2/entry#A0A5G2R5J2-1", "sequence": { "sequence": "MAQENAAFSPGPEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSNAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGAGEGAGEGAGADKEQNGCLPPPESESKV", "length": 393, "header": "tr|A0A5G2R5J2-1|A0A5G2R5J2_PIG Isoform 1 of G protein-activated inward rectifier potassium channel 3 OS=Sus scrofa OX=9823 GN=KCNJ9 PE=3 SV=1 CANONICAL=A0A5G2R5J2-1" }, "locus": { "chromosome": "4", "start_pos": 90409949, "end_pos": 90405410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082778.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082778.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072352.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072352.1" } ] } }, { "isoform_ac": "A0A8D0QKJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2/entry#A0A8D0QKJ6-1", "sequence": { "sequence": "MAQENAAFSPGPEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSNAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEKGHSYGTGKFPD", "length": 371, "header": "tr|A0A8D0QKJ6-1|A0A5G2R5J2_PIG Computationally mapped isoform of G protein-activated inward rectifier potassium channel 3 OS=Sus scrofa OX=9823 GN=KCNJ9 PE=3 SV=1 CANONICAL=A0A5G2R5J2-1" }, "locus": { "chromosome": "4", "start_pos": 90409949, "end_pos": 90398091, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047507.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047507.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046754.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046754.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0QKJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8D0QKJ6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152828", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152828", "resource": "KEGG Pathway" }, { "id": "R-SSC-1296041", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296041", "resource": "Reactome", "description": "Activation of G protein gated Potassium channels" }, { "id": "R-SSC-997272", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "resource": "Reactome", "description": "Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G-protein activated inward rectifier potassium channel activity", "id": "GO:0015467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015467", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2" } ], "pmid": "" }, { "name": "parallel fiber to Purkinje cell synapse", "id": "GO:0098688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098688", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2" } ], "pmid": "" }, { "name": "I(KACh) inward rectifier potassium channel complex", "id": "GO:1990566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990566", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "potassium ion import across plasma membrane", "id": "GO:1990573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990573", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2" } ], "pmid": "" }, { "name": "regulation of presynaptic membrane potential", "id": "GO:0099505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099505", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5J2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R5J2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 393, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R5J2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5J2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2" }, { "id": "PF17655", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17655" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Inward rectifier potassium channel C-terminal", "eco_id": "ECO_0000259", "start_pos": 171, "end_pos": 341, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5J2" }, { "id": "PF01007", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01007" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel inwardly rectifying transmembrane", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 164, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R5M8-1", "uniprot_ac": "A0A5G2R5M8", "uniprot_id": "A0A5G2R5M8_PIG", "mass": { "chemical_mass": 35234.0, "monoisotopic_mass": 35234.0 }, "refseq": { "ac": "XP_020921982", "name": "olfactory receptor 4D2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921982" }, "gene_names": [ { "name": "LOC100513817", "type": "recommended", "evidence": [ { "id": "A0A5G2R5M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8" } ] }, { "name": "LOC100513817", "type": "synonym", "evidence": [ { "id": "XP_020921982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921982" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R5M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4D2", "type": "synonym", "evidence": [ { "id": "XP_020921982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921982" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5M8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5M8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100513817", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8", "locus": {} } ], "crossref": [ { "id": "A0A5G2R5M8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5M8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513817", "url": "https://www.ncbi.nlm.nih.gov/gene/100513817", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513817", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513817", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IYQLALM", "url": "https://omabrowser.org/oma/group/IYQLALM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R5M8", "url": "https://www.orthodb.org/?gene=A0A5G2R5M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020921982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921982", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R5M8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGNLTWVSEFVFLGLSQTRELQLLLFLVFLFVYTTAVIGNLLITVTVTSESRLHTPMYFLLRNLALLDLCFSSVTAPKMLVDLLSEKKTISYEGCMAQLFFFHFLGGAMVFFLSVMAYDRLVAISRPLHYVTIMNTQLCVGLVVTAWMVGFVHSISQLALMLPLPFCGPNVLDNFYCDVPQVLRLACTDTSVLEFLMICNSGMLDVIWFLLLLVSYSAILVMLRSHSGQARRKAASTCTTHIIVVSMVFIPSIYLYARPFTSFPMDKAVSISHTVMTPMFNPLIYTLRNQEMQAAVKRLGRHWVLFKRE", "length": 311, "header": "tr|A0A5G2R5M8-1|A0A5G2R5M8_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100513817 PE=3 SV=1 CANONICAL=A0A5G2R5M8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R5M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8/entry#A0A5G2R5M8-1", "sequence": { "sequence": "MEPGNLTWVSEFVFLGLSQTRELQLLLFLVFLFVYTTAVIGNLLITVTVTSESRLHTPMYFLLRNLALLDLCFSSVTAPKMLVDLLSEKKTISYEGCMAQLFFFHFLGGAMVFFLSVMAYDRLVAISRPLHYVTIMNTQLCVGLVVTAWMVGFVHSISQLALMLPLPFCGPNVLDNFYCDVPQVLRLACTDTSVLEFLMICNSGMLDVIWFLLLLVSYSAILVMLRSHSGQARRKAASTCTTHIIVVSMVFIPSIYLYARPFTSFPMDKAVSISHTVMTPMFNPLIYTLRNQEMQAAVKRLGRHWVLFKRE", "length": 311, "header": "tr|A0A5G2R5M8-1|A0A5G2R5M8_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100513817 PE=3 SV=1 CANONICAL=A0A5G2R5M8-1" }, "locus": { "chromosome": "12", "start_pos": 34408664, "end_pos": 34407732, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086376.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086376.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071625.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071625.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5M8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513817", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513817", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P58180-1", "protein_name": "Olfactory receptor 4D2", "gene_name": "OR4D2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGNLTWVSDFVFLGLSQTRELQRFLFLMFLFVYITTVMGNILIIITVTSDSQLHTPMYFLLRNLAVLDLCFSSVTAPKMLVDLLSEKKTISYQGCMGQIFFFHFLGGAMVFFLSVMAFDRLIAISRPLRYVTVMNTQLWVGLVVATWVGGFVHSIVQLALMLPLPFCGPNILDNFYCDVPQVLRLACTDTSLLEFLKISNSGLLDVVWFFLLLMSYLFILVMLRSHPGEARRKAASTCTTHIIVVSMIFVPSIYLYARPFTPFPMDKLVSIGHTVMTPMLNPMIYTLRNQDMQAAVRRLGRHRLV", "length": 307 }, "evidence": [ { "id": "A0A5G2R5M8", "url": "https://omabrowser.org/oma/group/A0A5G2R5M8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5M8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5M8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5M8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R5M8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R5M8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5M8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R5M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5M8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R5Q3-1", "uniprot_ac": "A0A5G2R5Q3", "uniprot_id": "A0A5G2R5Q3_PIG", "mass": { "chemical_mass": 21135.0, "monoisotopic_mass": 21135.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "exodeoxyribonuclease III", "type": "recommended", "evidence": [ { "id": "A0A5G2R5Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3/entry#names_and_taxonomy" } ] }, { "name": "3.1.11.2", "type": "synonym", "evidence": [ { "id": "A0A5G2R5Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3", "locus": {} } ], "crossref": [ { "id": "A0A5G2R5Q3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5Q3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000048815", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000048815", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09076", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09076", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22748", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22748", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22748:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22748:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAINTELSIITLNANGLNAPIKRHRVAYWVKKQKPTICCLQENHLRTKDTYRFKVRGWEKTFHANGQHRKAGVAILISDKIDLKMRAIKKDKGHYLMVNRSIQEEDITIINIYALDIGAPRYLQQILTDIKGEIDGNTVLVEDFNTPLLSMKRPSRQKINKATEILNDTTEKLDLIDIFRTLH", "length": 183, "header": "tr|A0A5G2R5Q3-1|A0A5G2R5Q3_PIG Isoform 1 of exodeoxyribonuclease III OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2R5Q3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R5Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3/entry#A0A5G2R5Q3-1", "sequence": { "sequence": "MAINTELSIITLNANGLNAPIKRHRVAYWVKKQKPTICCLQENHLRTKDTYRFKVRGWEKTFHANGQHRKAGVAILISDKIDLKMRAIKKDKGHYLMVNRSIQEEDITIINIYALDIGAPRYLQQILTDIKGEIDGNTVLVEDFNTPLLSMKRPSRQKINKATEILNDTTEKLDLIDIFRTLH", "length": 183, "header": "tr|A0A5G2R5Q3-1|A0A5G2R5Q3_PIG Isoform 1 of exodeoxyribonuclease III OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2R5Q3-1" }, "locus": { "chromosome": "15", "start_pos": 43194976, "end_pos": 43194428, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085892.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085892.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069475.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069475.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3" } ], "pmid": "" }, { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3" } ], "pmid": "" }, { "name": "DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0003906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003906", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3" } ], "pmid": "" }, { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3" } ], "pmid": "" }, { "name": "double-stranded DNA 3'-5' DNA exonuclease activity", "id": "GO:0008311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008311", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R5Q3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 183, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R5Q3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5Q3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R5Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3" }, { "id": "PF03372", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endonuclease/exonuclease/phosphatase", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 84, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A5G2R5Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3#function" }, { "id": "A0A5G2R5Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 13, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 13, "end_pos": 13, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R5Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3#function" }, { "id": "A0A5G2R5Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Q3" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 42, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 42, "end_pos": 42, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R5V0-1", "uniprot_ac": "A0A5G2R5V0", "uniprot_id": "A0A5G2R5V0_PIG", "mass": { "chemical_mass": 35385.0, "monoisotopic_mass": 35385.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0", "locus": {} } ], "crossref": [ { "id": "A0A5G2R5V0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5V0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100623704", "url": "https://www.ncbi.nlm.nih.gov/gene/100623704", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623704", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623704", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LIWVEPR", "url": "https://omabrowser.org/oma/group/LIWVEPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R5V0", "url": "https://www.orthodb.org/?gene=A0A5G2R5V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003358916", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358916", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R5V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEDNCSLTTEFILTGFTDHPELKTLLFLVFLTIYLITMVGNLGLVALIFTEHRLHKPMYIFLGNLALMDSCCSSAITPKMLQNFFSKDRMISLYECMAQFYFLCLAESADSFLLAGMAYDRYVAICNPLQYHTMMSKKHCIQIITGVYVAGYLHPMIHVGLLFRLTFRGSHQINHFFCDVLPLYRLSCVDPYINELMIFIFGGLVQIFTVLIVIISYLFILLTIFKMKSNKGRGKALSTCASHFLSVSIFYGSLLFMYIRPNPVKKEDEDIPIAIFYTLVVPLLNPFIYSLRNKEVINVMKKIMKMT", "length": 308, "header": "tr|A0A5G2R5V0-1|A0A5G2R5V0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R5V0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R5V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0/entry#A0A5G2R5V0-1", "sequence": { "sequence": "MTEDNCSLTTEFILTGFTDHPELKTLLFLVFLTIYLITMVGNLGLVALIFTEHRLHKPMYIFLGNLALMDSCCSSAITPKMLQNFFSKDRMISLYECMAQFYFLCLAESADSFLLAGMAYDRYVAICNPLQYHTMMSKKHCIQIITGVYVAGYLHPMIHVGLLFRLTFRGSHQINHFFCDVLPLYRLSCVDPYINELMIFIFGGLVQIFTVLIVIISYLFILLTIFKMKSNKGRGKALSTCASHFLSVSIFYGSLLFMYIRPNPVKKEDEDIPIAIFYTLVVPLLNPFIYSLRNKEVINVMKKIMKMT", "length": 308, "header": "tr|A0A5G2R5V0-1|A0A5G2R5V0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R5V0-1" }, "locus": { "chromosome": "13", "start_pos": 162015294, "end_pos": 162014371, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078374.1", "url": "https://www.ensembl.org/id/ENSSSCT00000078374.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065965.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065965.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623704", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623704", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R5V0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 308, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R5V0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R5V0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R613-1", "uniprot_ac": "A0A5G2R613", "uniprot_id": "A0A5G2R613_PIG", "mass": { "chemical_mass": 304969.0, "monoisotopic_mass": 304969.0 }, "refseq": {}, "gene_names": [ { "name": "TENM1", "type": "recommended", "evidence": [ { "id": "A0A5G2R613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ] } ], "protein_names": [ { "name": "Teneurin-1", "type": "recommended", "evidence": [ { "id": "A0A5G2R613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613/entry#names_and_taxonomy" } ] }, { "name": "Protein Odd Oz/ten-m homolog 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613/entry#names_and_taxonomy" } ] }, { "name": "Tenascin-M1", "type": "synonym", "evidence": [ { "id": "A0A5G2R613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613/entry#names_and_taxonomy" } ] }, { "name": "Teneurin transmembrane protein 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Induces gene transcription activation.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613#function" }, { "database": "UniProtKB", "id": "ARBA00057184", "url": "https://www.uniprot.org/uniprotkb/ARBA00057184#function" }, { "database": "UniProtKB", "id": "F1RU60", "url": "https://www.uniprot.org/uniprotkb/F1RU60#function" } ] }, { "annotation": "Involved in neural development, regulating the establishment of proper connectivity within the nervous system. May function as a cellular signal transducer.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613#function" }, { "database": "UniProtKB", "id": "ARBA00053699", "url": "https://www.uniprot.org/uniprotkb/ARBA00053699#function" }, { "database": "UniProtKB", "id": "F1RU60", "url": "https://www.uniprot.org/uniprotkb/F1RU60#function" } ] }, { "annotation": "Plays a role in the regulation of neuroplasticity in the limbic system. Mediates a rapid reorganization of actin- and tubulin-based cytoskeleton elements with an increase in dendritic arborization and spine density formation of neurons in the hippocampus and amygdala. Induces BDNF transcription inhibition in neurons. Activates the mitogen-activated protein (MAP) kinase 2 (MEK2) and extracellular signal-regulated kinase (ERK) cascade. Also acts as a bioactive neuroprotective peptide on limbic neurons of the brain and regulates stress-induced behavior: attenuates alkalosis-associated necrotic cell death and the effects of corticotropin-releasing factor (CRF) on c-fos/FOS induction and on the reinstatement of cocaine seeking.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613#function" }, { "database": "UniProtKB", "id": "ARBA00058594", "url": "https://www.uniprot.org/uniprotkb/ARBA00058594#function" }, { "database": "UniProtKB", "id": "F1RU60", "url": "https://www.uniprot.org/uniprotkb/F1RU60#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TENM1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613", "locus": { "chromosome": "X", "start_pos": 101856267, "end_pos": 102641186, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012644", "url": "https://www.ensembl.org/id/ENSSSCG00000012644" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012644", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012644", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100520416", "url": "https://www.ncbi.nlm.nih.gov/gene/100520416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006530", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006530", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520416", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520416", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RU60", "url": "https://www.orthodb.org/?gene=F1RU60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11219:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11219:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15636", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15636", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23538", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23538", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24329", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24329", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25021", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25021", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R613-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU60", "url": "https://www.uniprot.org/uniprotkb/F1RU60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU60-1", "url": "https://www.uniprot.org/uniprotkb/F1RU60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQTDCKPYQPLSKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQSRKRKEVEKSTQEMEFCETPHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDMQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQESVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVIAVHLFGLTWQLQPAEGQLYENGVSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKSSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRNGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPICQEQCSGHGTFILDTGMCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCAEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQPLFSQHTSRLFYDRIKFLIGKDSTHVIPPEISFDSRRACVIRGQVVAVDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVVLIFDRSPFLSEKRTLWLPWNQFIVVEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLMQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYEMCPDFILWEKRTVILQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELSTSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRRIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEISIMAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNLYEIASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNAEGDLGAITSSNGNSVHIRRDASGIPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLEKLTKVELDTSNRENVLMSTNLTATTTIYILKQENTQSTYRVSPDGSLRVTFTSGMEISLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHMTRTGKIYDDHRKFTLRILYDQTGRPVLWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVILLLHSQRRYIFEYDQSDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEILYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNMGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGNSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYADLANPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWKELNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIGSWLELFGFQLHNVLPGFPKPELGNLELTYELLQLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYSDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEMARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR", "length": 2725, "header": "tr|A0A5G2R613-1|A0A5G2R613_PIG Isoform 1 of Teneurin-1 OS=Sus scrofa OX=9823 GN=TENM1 PE=3 SV=1 CANONICAL=A0A5G2R613-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R613-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613/entry#A0A5G2R613-1", "sequence": { "sequence": "MEQTDCKPYQPLSKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQSRKRKEVEKSTQEMEFCETPHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDMQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQESVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVIAVHLFGLTWQLQPAEGQLYENGVSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKSSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRNGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPICQEQCSGHGTFILDTGMCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCAEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQPLFSQHTSRLFYDRIKFLIGKDSTHVIPPEISFDSRRACVIRGQVVAVDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVVLIFDRSPFLSEKRTLWLPWNQFIVVEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLMQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYEMCPDFILWEKRTVILQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELSTSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRRIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEISIMAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNLYEIASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNAEGDLGAITSSNGNSVHIRRDASGIPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLEKLTKVELDTSNRENVLMSTNLTATTTIYILKQENTQSTYRVSPDGSLRVTFTSGMEISLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHMTRTGKIYDDHRKFTLRILYDQTGRPVLWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVILLLHSQRRYIFEYDQSDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEILYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNMGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGNSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYADLANPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWKELNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIGSWLELFGFQLHNVLPGFPKPELGNLELTYELLQLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYSDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEMARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR", "length": 2725, "header": "tr|A0A5G2R613-1|A0A5G2R613_PIG Isoform 1 of Teneurin-1 OS=Sus scrofa OX=9823 GN=TENM1 PE=3 SV=1 CANONICAL=A0A5G2R613-1" }, "locus": { "chromosome": "X", "start_pos": 102411139, "end_pos": 101857199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075291.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075291.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071775.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071775.1" } ] } }, { "isoform_ac": "F1RU60-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613/entry#F1RU60-1", "sequence": { "sequence": "MEQTDCKPYQPLSKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQSRKRKEVEKSTQEMEFCETPHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDMQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQESVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVIAVHLFGLTWQLQPAEGQLYENGVSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKSSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRNGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPICQEQCSGHGTFILDTGMCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCAEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQPLFSQHTSRLFYDRIKFLIGKDSTHVIPPEISFDSRRACVIRGQVVAVDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVVLIFDRSPFLSEKRTLWLPWNQFIVVEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLMQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYEMCPDFILWEKRTVILQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRRIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEISIMAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNLYEIASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNAEGDLGAITSSNGNSVHIRRDASGIPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLEKLTKVELDTSNRENVLMSTNLTATTTIYILKQENTQSTYRVSPDGSLRVTFTSGMEISLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHMTRTGKIYDDHRKFTLRILYDQTGRPVLWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVILLLHSQRRYIFEYDQSDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEILYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNMGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGNSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYADLANPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWKELNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIGSWLELFGFQLHNVLPGFPKPELGNLELTYELLQLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYSDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEMARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR", "length": 2732, "header": "tr|F1RU60-1|A0A5G2R613_PIG Computationally mapped isoform of Teneurin-1 OS=Sus scrofa OX=9823 GN=TENM1 PE=3 SV=4 CANONICAL=A0A5G2R613-1" }, "locus": { "chromosome": "X", "start_pos": 102411139, "end_pos": 101857199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013825.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013825.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013443.4", "url": "https://www.ensembl.org/id/ENSSSCP00000013443.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 720, "start_aa": "Thr", "end_pos": 720, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr720", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RU60", "url": "https://www.uniprot.org/uniprotkb/F1RU60" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520416", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520416", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ], "pmid": "" }, { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R613", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1084, "end_pos": 1086, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1550, "end_pos": 1552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1567, "end_pos": 1569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1663, "end_pos": 1665, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1699, "end_pos": 1701, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1757, "end_pos": 1759, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1781, "end_pos": 1783, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1842, "end_pos": 1844, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2056, "end_pos": 2058, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2145, "end_pos": 2147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2285, "end_pos": 2287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2602, "end_pos": 2604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 905, "end_pos": 907, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 592, "end_pos": 624, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R613" }, { "id": "PS51361", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51361" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Teneurin N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 318, "start_aa": "Met", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 720 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1084, "end_pos": 1086 }, { "start_pos": 1550, "end_pos": 1552 }, { "start_pos": 1567, "end_pos": 1569 }, { "start_pos": 1663, "end_pos": 1665 }, { "start_pos": 1699, "end_pos": 1701 }, { "start_pos": 1757, "end_pos": 1759 }, { "start_pos": 1781, "end_pos": 1783 }, { "start_pos": 1842, "end_pos": 1844 }, { "start_pos": 2056, "end_pos": 2058 }, { "start_pos": 2145, "end_pos": 2147 }, { "start_pos": 2285, "end_pos": 2287 }, { "start_pos": 2602, "end_pos": 2604 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 905, "end_pos": 907 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R647-1", "uniprot_ac": "A0A5G2R647", "uniprot_id": "A0A5G2R647_PIG", "mass": { "chemical_mass": 35622.0, "monoisotopic_mass": 35622.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100155823", "type": "recommended", "evidence": [ { "id": "A0A5G2R647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R647", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R647", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100155823", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647", "locus": {} } ], "crossref": [ { "id": "A0A5G2R647", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R647", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000047998", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000047998", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R647", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R647-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRNPMDGANHSVVSEFVFLGITNSWEIQLLLFVFTSMFYMASMMGNSLIMFTATSDPRLHSPMYFLLANLSFIDMGVSSVTSPKMIYDLFRKRKVISFSGCITQIFFIHVIGGVEVVVLIAMAFDRYVAICKPLHYLTIMSPRMCISFLVAAWMTGLIHSTVQLAFVVNLPFCGPNVLDSFYCDLPRFIKLACIDTDQLEFMVTANSGFISVGSFFILIISYIVIILTVKKQSSAGSSKALSTLSAHISVVVLFFGPLIFVYTWPSPSIPLDKFLAIFDAVLTPFLNSVIYTFRNQDMKVAMRRVCQQLMSYRKIS", "length": 317, "header": "tr|A0A5G2R647-1|A0A5G2R647_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100155823 PE=3 SV=2 CANONICAL=A0A5G2R647-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R647-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647/entry#A0A5G2R647-1", "sequence": { "sequence": "MVRNPMDGANHSVVSEFVFLGITNSWEIQLLLFVFTSMFYMASMMGNSLIMFTATSDPRLHSPMYFLLANLSFIDMGVSSVTSPKMIYDLFRKRKVISFSGCITQIFFIHVIGGVEVVVLIAMAFDRYVAICKPLHYLTIMSPRMCISFLVAAWMTGLIHSTVQLAFVVNLPFCGPNVLDSFYCDLPRFIKLACIDTDQLEFMVTANSGFISVGSFFILIISYIVIILTVKKQSSAGSSKALSTLSAHISVVVLFFGPLIFVYTWPSPSIPLDKFLAIFDAVLTPFLNSVIYTFRNQDMKVAMRRVCQQLMSYRKIS", "length": 317, "header": "tr|A0A5G2R647-1|A0A5G2R647_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100155823 PE=3 SV=2 CANONICAL=A0A5G2R647-1" }, "locus": { "chromosome": "AEMK02000661.1", "start_pos": 80835, "end_pos": 79885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077208.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077208.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069606.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069606.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R647", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R647", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R647", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R647", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R647-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 317, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R647-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R647" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R647" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 292, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R3G8-1", "uniprot_ac": "A0A5G2R3G8", "uniprot_id": "A0A5G2R3G8_PIG", "mass": { "chemical_mass": 67854.0, "monoisotopic_mass": 67854.0 }, "refseq": { "ac": "XP_003128731", "name": "tyrosyl-DNA phosphodiesterase 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128731" }, "gene_names": [ { "name": "TDP1", "type": "recommended", "evidence": [ { "id": "A0A5G2R3G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ] }, { "name": "TDP1", "type": "synonym", "evidence": [ { "id": "XP_003128731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128731" } ] } ], "protein_names": [ { "name": "Tyrosyl-DNA phosphodiesterase 1", "type": "recommended", "evidence": [ { "id": "A0A5G2R3G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8/entry#names_and_taxonomy" } ] }, { "name": "tyrosyl-DNA phosphodiesterase 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_003128731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128731" } ] } ], "function": [ { "annotation": "DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8#function" }, { "database": "UniProtKB", "id": "ARBA00054472", "url": "https://www.uniprot.org/uniprotkb/ARBA00054472#function" }, { "database": "UniProtKB", "id": "A0A5G2QDW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDW7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TDP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8", "locus": { "chromosome": "7", "start_pos": 111853249, "end_pos": 111767089, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002431", "url": "https://www.ensembl.org/id/ENSSSCG00000002431" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002431", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002431", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09193", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09193", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09195", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09195", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100153247", "url": "https://www.ncbi.nlm.nih.gov/gene/100153247", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153247", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153247", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PLIKECW", "url": "https://omabrowser.org/oma/group/PLIKECW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R3G8", "url": "https://www.orthodb.org/?gene=A0A5G2R3G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12415", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12415", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12415:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12415:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5693571", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693571", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003128731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128731", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QDW7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QDW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQEGDYGRWTISSSDESEEEKPKPDKPSTSLLPHAGQGAAHEPKYTCSEARRAAHRRKIDPVRFRNADPVSEASPPKRQKSGSQEDLGWCLSSSEDELPPEKQQKPAKEAGIKEEKGPPSPRDGSGHRSPPASHGLKEEEEEHETSGGGQDIWDMLDKGNPFQFYLTRVSGIKPKYNSGALHIRDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPVLLVHGDKREAKAHLHAQAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSPLYQRIVPGSHRSGESATHFKADLISYLSAYNAAALKEWIDTIQEHDLSETNVYLIGSTPGRFQGDQKDNWGHFRLRKLLKENGSSIPKAESWPVVGQFSSISSMGADESKWLCSEFKESLVTLGKESRTPGGAVPLHLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQTWLHSYFHKWSAATSGRSNAMPHIKTYMRPSPDFSQIAWFLVTSANLSKAAWGALEKNGSQLMIRSYELGVLFLPAAFGLDSFRVKQKFFSGSQEPTASFPVPYDLPPELYGSKDRPWIWNIPYMKAPDTHGNMWVPS", "length": 606, "header": "tr|A0A5G2R3G8-1|A0A5G2R3G8_PIG Isoform 1 of Tyrosyl-DNA phosphodiesterase 1 OS=Sus scrofa OX=9823 GN=TDP1 PE=3 SV=1 CANONICAL=A0A5G2R3G8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QDW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8/entry#A0A5G2QDW7-1", "sequence": { "sequence": "MSQEGDYGRWTISSSDESEEEKPKPDKPSTSLLPHAGQGAAHEPKYTCSEARRAAHRRKIDPVRFRNADPVSEASPPKRQKSGSQEDLGWCLSSSEDELPPEKQQKPAKEAGIKEEKGPPSPRDGSGHRSPPASHGLKEEEEEHETSGGGQDIWDMLDKGNPFQFYLTRVSGIKPKYNSGALHIRDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPVLLVHGDKREAKAHLHAQAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSPLYQRIVPGSHRSGESATHFKADLISYLSAYNAAALKEWIDTIQEHDLSETNVYLIGSTPGRFQGDQKDNWGHFRLRKLLKENGSSIPKAESWPVVGQFSSISSMGADESKWLCSEFKESLVTLGKESRTPGGAVPLHLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQTWLHSYFHKWSAATSGRSNAMPHIKTYMRPSPDFSQIAWFLVTSANLSKAAWGALEKNGSQLMIRSYELGVLFLPAAFRRGRLRGIGSHCFGASWRPGLETQEDWRPRRGGDPGGPETQNGRTPRRTGDPGGPDIQENWRLRRTRDPGQLDTQEDRRPRRTGDPGPETQED", "length": 639, "header": "tr|A0A5G2QDW7-1|A0A5G2QDW7_PIG Computationally mapped isoform of Tyrosyl-DNA phosphodiesterase 1 OS=Sus scrofa OX=9823 GN=TDP1 PE=3 SV=2 CANONICAL=A0A5G2R3G8-1" }, "locus": { "chromosome": "7", "start_pos": 111837667, "end_pos": 111773271, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081222.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081222.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062833.2", "url": "https://www.ensembl.org/id/ENSSSCP00000062833.2" } ] } }, { "isoform_ac": "A0A5G2R3G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8/entry#A0A5G2R3G8-1", "sequence": { "sequence": "MSQEGDYGRWTISSSDESEEEKPKPDKPSTSLLPHAGQGAAHEPKYTCSEARRAAHRRKIDPVRFRNADPVSEASPPKRQKSGSQEDLGWCLSSSEDELPPEKQQKPAKEAGIKEEKGPPSPRDGSGHRSPPASHGLKEEEEEHETSGGGQDIWDMLDKGNPFQFYLTRVSGIKPKYNSGALHIRDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPVLLVHGDKREAKAHLHAQAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSPLYQRIVPGSHRSGESATHFKADLISYLSAYNAAALKEWIDTIQEHDLSETNVYLIGSTPGRFQGDQKDNWGHFRLRKLLKENGSSIPKAESWPVVGQFSSISSMGADESKWLCSEFKESLVTLGKESRTPGGAVPLHLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQTWLHSYFHKWSAATSGRSNAMPHIKTYMRPSPDFSQIAWFLVTSANLSKAAWGALEKNGSQLMIRSYELGVLFLPAAFGLDSFRVKQKFFSGSQEPTASFPVPYDLPPELYGSKDRPWIWNIPYMKAPDTHGNMWVPS", "length": 606, "header": "tr|A0A5G2R3G8-1|A0A5G2R3G8_PIG Isoform 1 of Tyrosyl-DNA phosphodiesterase 1 OS=Sus scrofa OX=9823 GN=TDP1 PE=3 SV=1 CANONICAL=A0A5G2R3G8-1" }, "locus": { "chromosome": "7", "start_pos": 111852954, "end_pos": 111773271, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079812.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079812.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068742.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068742.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 357, "start_aa": "Thr", "end_pos": 357, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr357", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153247", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153247", "resource": "KEGG Pathway" }, { "id": "R-SSC-5693571", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693571", "resource": "Reactome", "description": "Nonhomologous End-Joining (NHEJ)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YVD4-1", "protein_name": "Tyrosyl-DNA phosphodiesterase 1", "gene_name": "TDP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLQEGAHGRWTVSSSEDSTEENSDSEKPSTSSLLSAPRSEASGPQYPCSEARKVAHKRKASPLRFSDTHLPAQTPPAEKQRPGQEGLGWCLSSSDEEPEDREKHTRKETLKEEKCDAPREQPQSHCKDEHSKNEKAEDYNEVLGEPQDTWDLLSGGNPFGFFLTKVRGIEQSYNSGALHIKDILSPLFGTLVSSAQFNYCIDVAWLVRQYPQEYRKKPLLIVHGEKRESKAELLAQARPFENISFCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIAEDWHQKTQGIWLSPLYPRLPQGSSDSAGESETNFKSDLISYLMAYSSPVLKEWIDLIREHDLSETRVYLLGSTPGRYQGIDKEKWGHLKLRKLLKDHASSIPAQESWPVVGQFSSIGSLGADGSKWLCSEFQESLVAAGSGVAALLKCDVPIHLVYPTVSNVRQSLEGYPAGGSLPYSIQTAQKQLWLHSYFHKWSAEVSGRSHAMPHIKTYMRPSHDFQKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELGVLFLPSAFGLDKGYFHVKGNMPSEGKDSATSFPVPFDLPPERYGSKDQPWIWNIPYTSAPDTHGNMWVPS", "length": 606 }, "evidence": [ { "id": "A0A5G2R3G8", "url": "https://omabrowser.org/oma/group/A0A5G2R3G8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F8W5U2-1", "protein_name": "Tyrosyl-DNA phosphodiesterase 1", "gene_name": "tdp1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQDSQHGKWSISDSEDEDIIPPTPQKDSVKPIVKPDSQSKPEETPTFLKQEPRLSPKRNENSVKTASAPSMGSEARKSAHVNQANPVKYERNASPAVKRKRETEEGGWNLSSSDDETPAPRNEPQKVNISPKRKKKTEDKRPPSPHGTSYYKEEPADFFETNLMPTNDIYRFYLNKVTGIPKKYNTGALHIKEILSPMFGTLKESVQFNYCFDIPWMVEQYPPEFRNKPVVLVHGEKRESKACLIEQAKPYPHISFCQAKLDIAFGTHHTKMMLLWYEEGFRVIILTSNLIRADWYQKTQGMWMSPLYPRLPQGSPGTAGESLTGFKRDLLEYLEAYRAPELANWIERIKQHDLSETRVYLIGSTPGRYQGPAMEKWGHLRLRKLLSEHTQPMQNEERWHVLGQFSSIGSMGLDKTKWLAAEFQRTLTTLGKAGKSLASPETQMLLIYPSVENVRTSLEGYPAGGSLPYSIQTAQKQLWLHSYFHGWHADVTGRSNAMPHIKTYMRISPDFTQLAWFLVTSANLSKAAWGALEKNNTQIMVRSYELGVLYLPSAFNMSTFPVEKNVFPACSSSIGFPVPFDLPPQRYSSKDRPWIWNIPYTQAPDTHGNVWVPS", "length": 615 }, "evidence": [ { "id": "A0A5G2R3G8", "url": "https://omabrowser.org/oma/group/A0A5G2R3G8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HBG4-1", "protein_name": "Tyrosyl-DNA phosphodiesterase 1", "gene_name": "Tdp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQESNYGKWTISSSDESEDEKPKPDKPSTSSPHQAGQGASKESTYTCSEARKVAHKRQLFPVKFSNIDSVLLPKKQKSDSTESLGWCLSSSDDEQQPETKQEQPNKYMVDQEKKHVSPPNVTTAQKVIDRSPPASHRPQRADDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGIKAKYNSKALHIRDILSPLFGTLVSSAQFNYCFDVDWLIKQYPPEFRNKPILIVHGDKREDKAHLHAQAKPYANISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIREDWHQKTQGIWLSPLYPRLDQGSHTSGESSTHFKADLISYLMSYNAPSLQEWIDTIQEHDLSETNVYLVGSTPGRFQGSHKDNWGHFRLRKLLRTHAPSVPKDECWPIVGQFSSIGSLGPDESKWLCSEFKESLLALREDGRTPGKSAVPLHLIYPSVENVRTSLEGYPAGGSLPYGIQTAERQNWLHSYFHKWSAETSGRSNAMPHIKTYMRPSSDFNKLAWFLVTSANLSKAAWGTLEKNGTQLMIRSYELGVLFLPSAFGLDAFKVKQKFFSSSCEPTASFPVPYDLPPELYGSKDRPWIWNIPYVKAPDTHGNMWVPS", "length": 609 }, "evidence": [ { "id": "A0A5G2R3G8", "url": "https://omabrowser.org/oma/group/A0A5G2R3G8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4G056-1", "protein_name": "Tyrosyl-DNA phosphodiesterase 1", "gene_name": "Tdp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQESSYGKWTISSSDDSEDEKPKPVKPSTSSGPQAGQGVSKEPTYTCSEARKAAHKRQISPVKFNNTDSVLPHKKQKMDSPEGLGWCLSSSDDEQQPDVTQQEQPKGVPPQEKKYAPSANVTTAQKVEDRSPPDSHRAQRADEEYETSGEGQDIWDMLDKENPFQFYLTRVSGIKAKYNSKALHIKDILSPLFGTLVSSAQFNYCFDVNWLIKQYPPEFRKKPILLVHGDKREAKADLHAQAKPYANISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIREDWHQKTQGIWLSPLYPRIYQGNHTSGESSTHFKADLTSYLMAYNAPPLQEWIDIIQEHDLSETNVYLIGSTPGRFQGSHKDNWGHFRLRKLLQAHAPSAPRGECWPVVGQFSSIGSLGPDESKWLCSEFKESLLAVREEGRTPGRSAVPLHLIYPSVENVRTSLEGYPAGGSLPYGIQTAEKQRWLHPYFHKWSAETSGRSNAMPHIKTYMRPSPDFSKLAWFLVTSANLSKAAWGALEKNGAQLMIRSYELGVLFLPSAFGLDTFKVKQKFFSSSSEPMASFPVPYDLPPELYGSKDRPWIWNIPYVKAPDTHGNMWVPS", "length": 609 }, "evidence": [ { "id": "A0A5G2R3G8", "url": "https://omabrowser.org/oma/group/A0A5G2R3G8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BJ37-1", "protein_name": "Tyrosyl-DNA phosphodiesterase 1", "gene_name": "Tdp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQESSYGKWTISSSDESEDEKPKPDKPSASSHPQAGQGVSKELIYTCSEARKVAHKRQISPVKFNDADSVLPHKKQKSDSPEGLGWCLSSSDDDQQPDVTQQEQPKRVLPQEKKHVSSPDVTTAQKVVDRSPPASLRPQRADDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGIKAKYNSKALHIKDILSPLFGTLVSSAQFNYCFDVDWLIKQYPPEFRKNPILLVHGDKREAKADLHAQAKPYANISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIREDWHQKTQGIWLSPLYPRIDQGSHTAGESSTRFKADLTSYLTAYNAPPLQEWIDIIQEHDLSETNVYLIGSTPGRFQGSHRDNWGHFRLRKLLQAHAPSTPKGECWPIVGQFSSIGSLGPDESKWLCSEFKDSLLALREEGRPPGKSAVPLHLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQRWLHSYFHKWSAETSGRSNAMPHIKTYMRPSPDFSKLAWFLVTSANLSKAAWGALEKNGTQLMIRSYELGVLFLPSAFGLDTFKVKQKFFSSSCEPTASFPVPYDLPPELYRSKDRPWIWNIPYVKAPDTHGNMWVPS", "length": 609 }, "evidence": [ { "id": "A0A5G2R3G8", "url": "https://omabrowser.org/oma/group/A0A5G2R3G8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8H1D9-1", "protein_name": "Tyrosyl-DNA phosphodiesterase 1", "gene_name": "TDP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAHSQVAYLIPLKADLKEDNSSPRITLSEGPNIIGRGNVSIVDKRLSRKHITIIVSTSGSASLSVDGTNPVVIRSSGDGERKKVKPSEEVSVCNDDLIELIPGHHFFKLVLLNGRAAKKARKAEDDVEAIRRFCPPNEKLPSTFRLLSVDALPDWANTSCVSINDVIEGDVVAAILSNYMVDIDWLMSACPKLANIPQVMVIHGEGDGRQEYIQRKKPANWILHKPRLPISFGTHHSKAIFLVYPRGVRVVVHTANLIHVDWNNKSQGLWMQDFPWKDDDKDPPKGCGFEGDLIDYLNVLKWPEFTANLPGRGNVKINAAFFKKFDYSDATVRLIASVPGYHTGFNLNKWGHMKLRTILQECIFDREFRRSPLIYQFSSLGSLDEKWLAEFGNSLSSGITEDKTPLGPGDSLIIWPTVEDVRCSLEGYAAGNAIPSPLKNVEKPFLKKYWARWKADHSARGRAMPHIKTFTRYNDQKIAWFLLTSSNLSKAAWGALQKNNSQLMIRSYELGVLFLPSPIKTQGCVFSCTESNPSVMKAKQETKDEVEKRSKLVTMTWQGDRDLPEIISLPVPYQLPPKPYSPEDVPWSWDRGYSKKDVYGQVWPR", "length": 605 }, "evidence": [ { "id": "A0A5G2R3G8", "url": "https://omabrowser.org/oma/group/A0A5G2R3G8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NUW8-1", "protein_name": "Tyrosyl-DNA phosphodiesterase 1", "gene_name": "TDP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPNDGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGVKPKYNSGALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHAQAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSPLYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPGRFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESMLTLGKESKTPGKSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKWSAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELGVLFLPSAFGLDSFKVKQKFFAGSQEPMATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDTHGNMWVPS", "length": 608 }, "evidence": [ { "id": "A0A5G2R3G8", "url": "https://omabrowser.org/oma/group/A0A5G2R3G8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VQM4-1", "protein_name": "Tyrosyl-DNA phosphodiesterase 1", "gene_name": "Tdp1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKECPYGEKCYRKNPIHFGEFSHAHLDAIYAKGNESGDYEIPANYSSEMIHTQLKLLEKLFPKQATNKEQEAHSSSSKPAVTAPVASGSSSSGSLDTNPSGSSASGPAASQDTSNLAKKQKLNAKNIRDYIPVVIEKGGMAKKLERAAPYNMFLTAITDSKPTHSEPLSITLQEILDESLGEIESTVQINFMVDIGWLLGHYYFAGILDKPLLLLYGDESPELLSIGKFKQQVTAIRVKMPTPFATSHTKMMFLGYSDGSMRVVISTANLYEDDWHNRTQGLWISPKLPALPVDADTGAGESLTGFKQDLMLYLVEYKISQLQPWIARIRNSDFSAINVFFLGSVPGGHREGSVRGHPWGHARLASLLAKHAAPIDDRIPVVCQSSSIGSLGANVQAWIQQDFVNSLKKDSTPVGKLRQMPPFKMIYPSYGNVAGSHDGMLGGGCLPYGKNTNDKQPWLKDYLQQWKSSDRFRSRAMPHIKSYTRFNLEDQSVYWFVLTSANLSKAAWGCFNKNSNIQPCLRIANYEAGVLFLPRFVTGEDTFPLGNNRDGVPAFPLPYDVPLTPYAPDDKPFLMDYLQG", "length": 580 }, "evidence": [ { "id": "A0A5G2R3G8", "url": "https://omabrowser.org/oma/group/A0A5G2R3G8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "pmid": "" }, { "name": "single strand break repair", "id": "GO:0000012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000012", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "pmid": "" }, { "name": "exonuclease activity", "id": "GO:0004527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004527", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "pmid": "" }, { "name": "3'-tyrosyl-DNA phosphodiesterase activity", "id": "GO:0017005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017005", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "pmid": "" }, { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3G8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3G8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 357 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 246, "end_pos": 248 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 526, "end_pos": 528 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R216-1", "uniprot_ac": "A0A5G2R216", "uniprot_id": "A0A5G2R216_PIG", "mass": { "chemical_mass": 43592.0, "monoisotopic_mass": 43592.0 }, "refseq": {}, "gene_names": [ { "name": "MRPS31", "type": "recommended", "evidence": [ { "id": "A0A5G2R216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein mS31", "type": "recommended", "evidence": [ { "id": "A0A5G2R216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216/entry#names_and_taxonomy" } ] }, { "name": "28S ribosomal protein S31, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A5G2R216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R216", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MRPS31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216", "locus": { "chromosome": "11", "start_pos": 15450705, "end_pos": 15472314, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009372", "url": "https://www.ensembl.org/id/ENSSSCG00000009372" } ] } } ], "crossref": [ { "id": "A0A5G2R216", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R216", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009372", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009372", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "5AJ3", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5AJ3&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "5AJ4", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5AJ4&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6YDP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6YDP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6YDW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6YDW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NQH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NQH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NQL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NQL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8OIN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OIN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8OIP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OIP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR026299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EGYDNYP", "url": "https://omabrowser.org/oma/group/EGYDNYP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13231:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13231:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00005aj3", "url": "https://www.rcsb.org/structure/pdb_00005aj3", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00005aj4", "url": "https://www.rcsb.org/structure/pdb_00005aj4", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006ydp", "url": "https://www.rcsb.org/structure/pdb_00006ydp", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006ydw", "url": "https://www.rcsb.org/structure/pdb_00006ydw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nqh", "url": "https://www.rcsb.org/structure/pdb_00007nqh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nql", "url": "https://www.rcsb.org/structure/pdb_00007nql", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008oin", "url": "https://www.rcsb.org/structure/pdb_00008oin", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008oip", "url": "https://www.rcsb.org/structure/pdb_00008oip", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5AJ3", "url": "https://www.rcsb.org/structure/5AJ3", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5AJ4", "url": "https://www.rcsb.org/structure/5AJ4", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6YDP", "url": "https://www.rcsb.org/structure/6YDP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6YDW", "url": "https://www.rcsb.org/structure/6YDW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NQH", "url": "https://www.rcsb.org/structure/7NQH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NQL", "url": "https://www.rcsb.org/structure/7NQL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OIN", "url": "https://www.rcsb.org/structure/8OIN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OIP", "url": "https://www.rcsb.org/structure/8OIP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF15433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QIS6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R216", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R216-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RME2", "url": "https://www.uniprot.org/uniprotkb/F1RME2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RME2-1", "url": "https://www.uniprot.org/uniprotkb/F1RME2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPRVSAVIPLRPLSRLPLCSGGPEASAAAILLLDSLRGTVRTENNIQRYFGTNNLVYSKKDEQSGPTCEISKETESKGSVKENSKKDLLNIIKGMKVELSTVNVQTTKPSNKRQLKNLETAIGRIKKAPEDTPQKRSESLSSELVAAVSAVADSLPFDRRMTKSELLRQLQKHEEDSRDKKKKLIFSNIISDMKVARSATARVSTRPVHQIQFDEGTDDFADQEKTLNLKKRTNDNIFKKKDIYMNFAYFECCYSAEAVPSLWDIEFAKQLAAVTERPFQNGFEEMIQWTKEGKLWEFPINNEAGFDDDGSEFHEHIFLDKYLQDFPKQGPIRHFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKRVILKESGIQLN", "length": 381, "header": "tr|A0A5G2R216-1|A0A5G2R216_PIG Isoform 1 of Small ribosomal subunit protein mS31 OS=Sus scrofa OX=9823 GN=MRPS31 PE=1 SV=1 CANONICAL=A0A5G2R216-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QIS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216/entry#A0A5G2QIS6-1", "sequence": { "sequence": "MLPRVSAVIPLRPLSRLPLCSGGPEASAAAILLLDSLRGTVRYRISALLAPTENNIQRYFGTNNLVYSKKDEQSGPTCEISKETESKGSVKENSKKDLLNIIKGMKVELSTVNVQTTKPSNKRQLKNLETAIGRIKKAPEDTPQKRSESLSSELVAAVSAVADSLPFDRRMTKSELLRQLQKHEEDSRLRRMERSLKLGYFSNIISDMKVARSATARVSTRPVHQIQFDEGTDDFADQEKTLNLKKRTNDNIFKKKDIYMNFAYFECCYSAEAVPSLWDIEFAKQLAAVTERPFQNGFEEMIQWTKEGKLWEFPINNEAGFDDDGSEFHEHIFLDKYLQDFPKQGPIRHFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKRVILKESGIQLN", "length": 395, "header": "tr|A0A5G2QIS6-1|A0A5G2QIS6_PIG Computationally mapped isoform of Small ribosomal subunit protein mS31 OS=Sus scrofa OX=9823 GN=MRPS31 PE=1 SV=1 CANONICAL=A0A5G2R216-1" }, "locus": { "chromosome": "11", "start_pos": 15472224, "end_pos": 15450775, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075733.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075733.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064346.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064346.1" } ] } }, { "isoform_ac": "A0A5G2R216-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216/entry#A0A5G2R216-1", "sequence": { "sequence": "MLPRVSAVIPLRPLSRLPLCSGGPEASAAAILLLDSLRGTVRTENNIQRYFGTNNLVYSKKDEQSGPTCEISKETESKGSVKENSKKDLLNIIKGMKVELSTVNVQTTKPSNKRQLKNLETAIGRIKKAPEDTPQKRSESLSSELVAAVSAVADSLPFDRRMTKSELLRQLQKHEEDSRDKKKKLIFSNIISDMKVARSATARVSTRPVHQIQFDEGTDDFADQEKTLNLKKRTNDNIFKKKDIYMNFAYFECCYSAEAVPSLWDIEFAKQLAAVTERPFQNGFEEMIQWTKEGKLWEFPINNEAGFDDDGSEFHEHIFLDKYLQDFPKQGPIRHFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKRVILKESGIQLN", "length": 381, "header": "tr|A0A5G2R216-1|A0A5G2R216_PIG Isoform 1 of Small ribosomal subunit protein mS31 OS=Sus scrofa OX=9823 GN=MRPS31 PE=1 SV=1 CANONICAL=A0A5G2R216-1" }, "locus": { "chromosome": "11", "start_pos": 15472224, "end_pos": 15450775, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067812.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067812.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064573.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064573.1" } ] } }, { "isoform_ac": "F1RME2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216/entry#F1RME2-1", "sequence": { "sequence": "MLPRVSAVIPLRPLSRLPLCSGGPEASAAAILLLDSLRGTVRTENNIQRYFGTNNLVYSKKDEQSGPTCEISKETESKGSVKENSKKDLLNIIKGMKVELSTVNVQTTKPSNKRQLKNLETAIGRIKKAPEDTPQKRSESLSSELVAAVSAVADSLPFDRRMTKSELLRQLQKHEEDSRDKKKKLIFSNIISDMKVARSATARVSTRPVHQIQFDEGTDDFADQEKTLNLKKRKNIFKGRRLNIFEPQAVTEEAPETEAVPSLWDIEFAKQLAAVTERPFQNGFEEMIQWTKEGKLWEFPINNEAGFDDDGSEFHEHIFLDKYLQDFPKQGPIRHFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKRVILKESGIQLN", "length": 381, "header": "tr|F1RME2-1|A0A5G2R216_PIG Computationally mapped isoform of Small ribosomal subunit protein mS31 OS=Sus scrofa OX=9823 GN=MRPS31 PE=1 SV=3 CANONICAL=A0A5G2R216-1" }, "locus": { "chromosome": "11", "start_pos": 15472224, "end_pos": 15450775, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010269.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010269.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010002.3", "url": "https://www.ensembl.org/id/ENSSSCP00000010002.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Ribosome. The complete structure of the 55S mammalian mitochondrial ribosome.", "journal": "Science", "date": "2015", "authors": "Greber BJ, Bieri P, Leibundgut M, Leitner A, Aebersold R, Boehringer D, Ban N", "evidence": [ { "database": "UniProtKB", "id": "F1RME2", "url": "https://www.uniprot.org/uniprotkb/F1RME2" } ], "reference": [ { "type": "PubMed", "id": "25837512", "url": "https://glygen.org/publication/PubMed/25837512" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RME2", "url": "https://www.uniprot.org/uniprotkb/F1RME2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Structural insights into mammalian mitochondrial translation elongation catalyzed by mtEFG1.", "journal": "EMBO J.", "date": "2020", "authors": "Kummer E, Ban N", "evidence": [ { "database": "UniProtKB", "id": "F1RME2", "url": "https://www.uniprot.org/uniprotkb/F1RME2" } ], "reference": [ { "type": "PubMed", "id": "32602580", "url": "https://glygen.org/publication/PubMed/32602580" } ] }, { "title": "Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.", "journal": "Mol. Cell", "date": "2021", "authors": "Kummer Eva, Schubert Katharina Noel, Schoenhut Tanja, Scaiola Alain, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "F1RME2", "url": "https://www.uniprot.org/uniprotkb/F1RME2" } ], "reference": [ { "type": "PubMed", "id": "33878294", "url": "https://glygen.org/publication/PubMed/33878294" } ] }, { "title": "Molecular basis of translation termination at noncanonical stop codons in human mitochondria.", "journal": "Science", "date": "2023", "authors": "Saurer Martin, Leibundgut Marc, Nadimpalli Hima Priyanka, Scaiola Alain, Sch\u00f6nhut Tanja, Lee Richard G, Siira Stefan J, Rackham Oliver, Dreos Ren\u00e9, Lenar\u010di\u010d Tea, Kummer Eva, Gatfield David, Filipovska Aleksandra, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "F1RME2", "url": "https://www.uniprot.org/uniprotkb/F1RME2" } ], "reference": [ { "type": "PubMed", "id": "37141370", "url": "https://glygen.org/publication/PubMed/37141370" } ] } ], "pathway": [ { "id": "R-SSC-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-SSC-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-SSC-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "B0BN56-1", "protein_name": "Small ribosomal subunit protein mS31", "gene_name": "Mrps31", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLHRIPAFIRPRPFSGLPLSCGNREVSVAASVLPAAGSGAVRTENTIQRHFCTSRSICSKKDDQSVPANETSQKAAESQGEGKETLKKNLLDVIKDMKVQLNTANVKTTKPRGRQPPAHLETAVGRLQKALGEPPRKRNEFLSPELVAAASAVADSLPFDKQTTKSELLKQLQQHEEESRAQTDRQKRRVSFTQIISNMKIAKSPSMRVSSRPQHQIQFDEEVDSSLSQEKPADFRRRKCLFKGKRLSIFDVKAFDDEAPEPEAAPSLWEIEFAKQLATVSEQPFGNGFEEMIQWTKEGKLWEFPVNNEAGLDDDGSEFHEHIFLEKHLEDFPKQGPIRLFMELVTCGLSKNPYLSVRQKVEHIEWFRNYFNEKRDILKENNIHLTS", "length": 387 }, "evidence": [ { "id": "A0A5G2R216", "url": "https://omabrowser.org/oma/group/A0A5G2R216/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P82925-1", "protein_name": "Small ribosomal subunit protein mS31", "gene_name": "MRPS31", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFPRVSAVLPFRPLSRLPLCSAGPEASAATVVPLASPHGTVRTKCNIQRYFGTNSVIYSKKDDKSVPACEISKETENQGSTKENKKKDLVNIIKGMKVELSTVNVQTTKPPNRGQLKSLEAAIRRLQKSPEDAPQKSKSLSPELVAAATAVADSLPFDKQTTKSELLRQLRQHEEDSKAQKDGEKPKISFSNIISDMKVARSSTARASTRPVHQIQFDEGADDFVDREETADLRKRFRKNIFKGKRLNIFELKPVTEEAPETEAAPSLWDVEFAKQLAAVTEQPFQNGFEEMIQWTKEGKLWEFPINNEAGFDDDGSEFHEHIFLDKYLEGFPKQGPIRHFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKQDILKESGINFS", "length": 386 }, "evidence": [ { "id": "A0A5G2R216", "url": "https://omabrowser.org/oma/group/A0A5G2R216/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q61733-1", "protein_name": "Small ribosomal subunit protein mS31", "gene_name": "Mrps31", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLHRIPAFLRPRPFSGLPLSCGNRDVSVAVLPAAQSGAVRTENNIQRHFCTSRSICSKKVDQSVPANEISQKAAESQGRGKETLKKDLLDIIKDMKVDLSTANVKTPKPRGRKPSASLEATVDRLQKAPEDPPKKRNEFLSPELVAAASAVADSLPFDKQTTKSELLRQLQQHEEELRAQKDREKRRISFTHIISNMKIAKSPSGRASTRPQHQIQFDEDMDSSLKQEKPTDFRKRKYLFKGKRLSIFADKAFADEPPEPEASPSLWEIEFAKQLASVADQPFENGFEEMIQWTKEGKLWEFPVNNEAGLDDDGSEFHEHIFLDKYLEDFPKQGPIRLFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKRDILKENNIAFT", "length": 384 }, "evidence": [ { "id": "A0A5G2R216", "url": "https://omabrowser.org/oma/group/A0A5G2R216/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92665-1", "protein_name": "Small ribosomal subunit protein mS31", "gene_name": "MRPS31", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFPRVSTFLPLRPLSRHPLSSGSPETSAAAIMLLTVRHGTVRYRSSALLARTKNNIQRYFGTNSVICSKKDKQSVRTEETSKETSESQDSEKENTKKDLLGIIKGMKVELSTVNVRTTKPPKRRPLKSLEATLGRLRRATEYAPKKRIEPLSPELVAAASAVADSLPFDKQTTKSELLSQLQQHEEESRAQRDAKRPKISFSNIISDMKVARSATARVRSRPELRIQFDEGYDNYPGQEKTDDLKKRKNIFTGKRLNIFDMMAVTKEAPETDTSPSLWDVEFAKQLATVNEQPLQNGFEELIQWTKEGKLWEFPINNEAGFDDDGSEFHEHIFLEKHLESFPKQGPIRHFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKKDILKESNIQFN", "length": 395 }, "evidence": [ { "id": "A0A5G2R216", "url": "https://omabrowser.org/oma/group/A0A5G2R216/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial small ribosomal subunit", "id": "GO:0005763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R216", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R216", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R216", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R216" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R216-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 381, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R216-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R216" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R782-1", "uniprot_ac": "A0A5G2R782", "uniprot_id": "A0A5G2R782_PIG", "mass": { "chemical_mass": 91733.0, "monoisotopic_mass": 91733.0 }, "refseq": { "ac": "XP_020935958", "name": "oligophrenin-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935958" }, "gene_names": [ { "name": "OPHN1", "type": "recommended", "evidence": [ { "id": "A0A5G2R782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ] }, { "name": "OPHN1", "type": "synonym", "evidence": [ { "id": "XP_020935958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935958" } ] } ], "protein_names": [ { "name": "Oligophrenin-1", "type": "recommended", "evidence": [ { "id": "A0A5G2R782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782/entry#names_and_taxonomy" } ] }, { "name": "oligophrenin-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020935958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935958" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OPHN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782", "locus": { "chromosome": "X", "start_pos": 54055092, "end_pos": 54616959, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000022676", "url": "https://www.ensembl.org/id/ENSSSCG00000022676" } ] } } ], "crossref": [ { "id": "A0A5G2R782", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R782", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000022676", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022676", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01249", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01249", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04374", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07633", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07633", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515117", "url": "https://www.ncbi.nlm.nih.gov/gene/100515117", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515117", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515117", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KEAPQMC", "url": "https://omabrowser.org/oma/group/KEAPQMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R782", "url": "https://www.orthodb.org/?gene=A0A5G2R782", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12552", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12552", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12552:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12552:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16746", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16746", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013026", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013026", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013409", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020935958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935958", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QHF4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R782-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R784", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R784", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R784-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R784-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEU2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GNT5", "url": "https://www.uniprot.org/uniprotkb/K7GNT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GNT5-1", "url": "https://www.uniprot.org/uniprotkb/K7GNT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALIGAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTLTMMPMEQKPGAKQQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINVIESKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFNNSDWDIKTVTSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLEILIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFVKIYSGPPEESTAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHRTPNGTIISSIELPKPLQYPKIPMQRSGEADSGRKSPSRPVSEGKLESCLEVDVGKLVSRLQDGGTKALPKATNGPVPGTGPTKAPSFHIKRPAPRAMAHHKEGDSDSFSKVRPPGEKPTIIRPPVRPPDPPCRAATPQKPEPKPDIVAGNAGEIPSSVVASRTRFFETASRKTGSSQGRLPGDES", "length": 803, "header": "tr|A0A5G2R782-1|A0A5G2R782_PIG Isoform 1 of Oligophrenin-1 OS=Sus scrofa OX=9823 GN=OPHN1 PE=4 SV=1 CANONICAL=A0A5G2R782-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QHF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782/entry#A0A5G2QHF4-1", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALIGAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTLTMMPMEQKPGAKQQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINVIESKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFNNSDWDIKTVTSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLEILIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFVKIYSGPPEESTAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHRTPNGTIISSIELPKPLQYPKIPMQRSGEADSGRKSPSRPVSEGKLESCLEVDVGKLVSRLQDGGTKALPKATNGPVPGTGPTKAPSFHIKRPAPRAMAHHKEGDSDSFSKVRPPGEKPTIIRPPVRPPDPPCRAATPQKPEPKPDIVAGNAGEIPSSVVASRTRFFETASRKTGSSQGRLPGDES", "length": 769, "header": "tr|A0A5G2QHF4-1|A0A5G2R782_PIG Computationally mapped isoform of Oligophrenin-1 OS=Sus scrofa OX=9823 GN=OPHN1 PE=4 SV=2 CANONICAL=A0A5G2R782-1" }, "locus": { "chromosome": "X", "start_pos": 54616124, "end_pos": 54061719, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087587.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087587.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063779.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063779.2" } ] } }, { "isoform_ac": "A0A5G2QXS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782/entry#A0A5G2QXS5-1", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALIGAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTLTMMPMEQKPGAKQQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINVIESKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFNNSDWDIKTVTSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLEILIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFVKIYSGPPEESTAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHRTPNGTIISSIELPKPLQYPKIPMQRSGEADSGRKSPSRPVSEGKLESCLEVDVGKLVSRLQDGGTKALPKATNGPVPGTGPTKAPSFHIKRPAPRAMAHHKEGDSDSFSKVRPPGEKPTIIRPPVRPPDPPCRAATPQKPEPKPDIVAGNAGEIPSSVVASRTRFFETASRKTGRSEFLRTGMSCRSRGF", "length": 808, "header": "tr|A0A5G2QXS5-1|A0A5G2R782_PIG Computationally mapped isoform of Oligophrenin-1 OS=Sus scrofa OX=9823 GN=OPHN1 PE=4 SV=1 CANONICAL=A0A5G2R782-1" }, "locus": { "chromosome": "X", "start_pos": 54616124, "end_pos": 54060453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066482.1", "url": "https://www.ensembl.org/id/ENSSSCT00000066482.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069677.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069677.1" } ] } }, { "isoform_ac": "A0A5G2R782-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782/entry#A0A5G2R782-1", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALIGAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTLTMMPMEQKPGAKQQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINVIESKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFNNSDWDIKTVTSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLEILIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFVKIYSGPPEESTAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHRTPNGTIISSIELPKPLQYPKIPMQRSGEADSGRKSPSRPVSEGKLESCLEVDVGKLVSRLQDGGTKALPKATNGPVPGTGPTKAPSFHIKRPAPRAMAHHKEGDSDSFSKVRPPGEKPTIIRPPVRPPDPPCRAATPQKPEPKPDIVAGNAGEIPSSVVASRTRFFETASRKTGSSQGRLPGDES", "length": 803, "header": "tr|A0A5G2R782-1|A0A5G2R782_PIG Isoform 1 of Oligophrenin-1 OS=Sus scrofa OX=9823 GN=OPHN1 PE=4 SV=1 CANONICAL=A0A5G2R782-1" }, "locus": { "chromosome": "X", "start_pos": 54616124, "end_pos": 54061719, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073090.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073090.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066461.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066461.1" } ] } }, { "isoform_ac": "A0A5G2R784-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782/entry#A0A5G2R784-1", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALIGAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTLTMMPMEQKPGAKQQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINVIESKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFNNSDWDIKTVTSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLEILIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFVKIYSGPPEESTAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHRTPNGTIISSIELPKPLQYPKIPMQRSGEADSGRKSPSRPVSEGKLESCLEVDVGKLVSRLQDGGTKALPKATNGPVPGTGPTKAPSFHIKRPAPRAMAHHKEGDSDSFSKVRPPGEKPTIIRPPVRPPDPPCRAATPQKPEPKPDIVAGNAGEIPSSVSQGRLPGDES", "length": 786, "header": "tr|A0A5G2R784-1|A0A5G2R784_PIG Computationally mapped isoform of Oligophrenin-1 OS=Sus scrofa OX=9823 GN=OPHN1 PE=4 SV=1 CANONICAL=A0A5G2R782-1" }, "locus": { "chromosome": "X", "start_pos": 54616124, "end_pos": 54061719, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074672.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074672.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072940.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072940.1" } ] } }, { "isoform_ac": "A0A8W4FEU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782/entry#A0A8W4FEU2-1", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALIGAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTLTMMPMEQKPGAKQQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINVIESKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFNNSDWDIKTVTSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLEILIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFVKIYSGPPEESTAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHRTPNGTIISSIELPKPLQYPKIPMQRSGEADSGRKSPSRPVSEGKLESCLEVDVGKLVSRLQDGGTKALPKATNGPVPGTGPTKAPSFHIKRPAPRAMAHHKEGDSDSFSKVRPPGEKPTIIRPPVRPPDPPCRAATPQKPEPKPDIVAGNAGEIPSSVVASRTRFFETASRKTGSSQGRLPGDES", "length": 734, "header": "tr|A0A8W4FEU2-1|A0A5G2R782_PIG Computationally mapped isoform of Oligophrenin-1 OS=Sus scrofa OX=9823 GN=OPHN1 PE=4 SV=1 CANONICAL=A0A5G2R782-1" }, "locus": { "chromosome": "X", "start_pos": 54616124, "end_pos": 54061719, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094321.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094321.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076826.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076826.1" } ] } }, { "isoform_ac": "K7GNT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782/entry#K7GNT5-1", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALIGAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTLTMMPMEQKPGAKQQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINVIESKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFNNSDWDIKTVTSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLEILIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFVKIYSGPPEESTAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEGDSDSFSKVRPPGEKPTIIRPPVRPPDPPCRAATPQKPEPKPDIVAGNAGEIPSSVVASRTRFFETASRKTGSSQGRLPGDES", "length": 695, "header": "tr|K7GNT5-1|A0A5G2R782_PIG Computationally mapped isoform of Oligophrenin-1 OS=Sus scrofa OX=9823 GN=OPHN1 PE=4 SV=2 CANONICAL=A0A5G2R782-1" }, "locus": { "chromosome": "X", "start_pos": 54616124, "end_pos": 54061719, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033803.2", "url": "https://www.ensembl.org/id/ENSSSCT00000033803.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029540.2", "url": "https://www.ensembl.org/id/ENSSSCP00000029540.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 700, "start_aa": "Thr", "end_pos": 700, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr700", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXS5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXS5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515117", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515117", "resource": "KEGG Pathway" }, { "id": "R-SSC-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-SSC-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-SSC-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-SSC-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-SSC-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-SSC-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-SSC-9013409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013409", "resource": "Reactome", "description": "RHOJ GTPase cycle" }, { "id": "R-SSC-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N6J8-1", "protein_name": "Oligophrenin-1", "gene_name": "OPHN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALISAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTFTMTPMDQKPGAKQQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDIDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFVKIYSGPPEESTAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHRTPNGTISSSIEPPKPPQYPKMPMQKSVEADPGRKSPSRLVSDVKLETCLEVDVGKLVSRLQDGGTKAIPKASNGPVPGPGTTKAPSFHIKRSAPRPLAHHKEGDSDSFSKVRPPGEKPTIIRPPVRPPDPPCRATTTQKPEPKPDVMAGNAGEIPSSVVASRTRFFETASRKTGSSQGRLPGDES", "length": 803 }, "evidence": [ { "id": "A0A5G2R782", "url": "https://omabrowser.org/oma/group/A0A5G2R782/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0YHG8-1", "protein_name": "Oligophrenin-1", "gene_name": "OPHN1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALIAAIRSYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLQEVELERSMMVQNASDLLIKPLENFRKEQIGFTKERKKKFEKDGEKFYSMLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLEYVYQIQEVQESKKFSIVEPVLAFLHSLFTYNNLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREELEDLKKRMKEAPLTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKEAKTLRMTPMDQKPGAKQGTLDLTLKSCVRRKTDSIDKRFCFDIETNERSGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINAVETKGISTEGVYRTVGSNIQVQKLLNAFFDPKCPGDVDLQSSEWDIKTITSSLKFYLRNLSEPVMTYKLHKELVLAAKSENLDYRLGAIHALVYKLPDKNREMLELLIRHLVNVCEHSRENLMSPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYSGPPEDSAAPPVPPPRVAARRHKPITISKRPLRERPVFFGASVEESGADQLSQTPNGSIVTEAPRPLLRSRLPAPRPGGEEPGRPSAELEVGKLVPRLQDGGVKLSSKAANGVVSSPALRTSTLHARRPAPRPGGCGRDGEYDGVPRPRPHGDKPVIMRPPVRPPDPPCRAPIPQKLEQRPDLIAGTAEEVPSSVVASRTKFFETASRRTSSSSSPQGRIPGDES", "length": 789 }, "evidence": [ { "id": "A0A5G2R782", "url": "https://omabrowser.org/oma/group/A0A5G2R782/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O60890-1", "protein_name": "Oligophrenin-1", "gene_name": "OPHN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALISAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTLTMTPMEQKPGAKQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQQEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYLGPPEESAAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHQTPNGTITSSIEPPKPPQHPKLPIQRSGETDPGRKSPSRPILDGKLEPCPEVDVGKLVSRLQDGGTKITPKATNGPMPGSGPTKTPSFHIKRPAPRPLAHHKEGDADSFSKVRPPGEKPTIIRPPVRPPDPPCRAATPQKPEPKPDIVAGNAGEITSSVVASRTRFFETASRKTGSSQGRLPGDES", "length": 802 }, "evidence": [ { "id": "A0A5G2R782", "url": "https://omabrowser.org/oma/group/A0A5G2R782/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CAX5-1", "protein_name": "Oligophrenin-1", "gene_name": "Ophn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGSALISAMRSYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVQNASDLLIKPLETFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLLEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCRYEKETRTLTMTPTEQKPGAKQGPVDLTLKYCVRRKTESIDKRFCFDIEANERTGTITLQAPSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINFIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFYNSDWDIKTITSSLKFYLRNLSEPVMTYKLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIKHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYLGPPEDSQVPPVPPPRVTARRHKPITISKRLLREKAVFYTPSLDDVEDEIHHPTPNGTIASNLDPPKQLQHLKLPMQKSGEMDPGRKSPSRPVSDCQTEPCLEADMGKLVYRLQDGGTKAIPKASNGPVPGSGHTKTSSFHIKRPAPRPIVHHKEGDTDCFSKVRPPGEKQTIIRPPVRPPDPPCRSSTSQKPESKPETVSSNAEEIPSSVVASRTRFFETASRKTGSSQGKLPGDES", "length": 802 }, "evidence": [ { "id": "A0A5G2R782", "url": "https://omabrowser.org/oma/group/A0A5G2R782/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99J31-1", "protein_name": "Oligophrenin-1", "gene_name": "Ophn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRQRLKYYEEELERTNKFIKDVIKDGSALISAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVQNASDLLIKPLETFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLLEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWAKYYCRYEKETRMLTMIPMEQKPGAKQGPVDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQAPSEANRRLWMEAMDGKEPIYHTPITKQEEMELNEVGFKFVRKCINFIETKGIKTEGLYRTVGSNIQVQKLLYAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYKLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIKHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYLGPPEDSQVPPVPPPRVTARRHKPITISKRLLREKTVFYTSSLDENKDESHHQTPNGTITSNLDPPKLLQHLKPPMQKSGETDPGRKSPSRPVSDCQSEPCLETDVGRLLFRLQDGGTKATPKASNGPVPGSGHTKTSSFHIRRPAPRPMAHHKEGDTDGFSKVRPPGEKQTIIRPPVRPPDPPCRSITPQKPEPKPETGSGNADEIPSSVVASRTRFFETASRKTGSSQGKLPGDES", "length": 802 }, "evidence": [ { "id": "A0A5G2R782", "url": "https://omabrowser.org/oma/group/A0A5G2R782/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 16, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "cell junction assembly", "id": "GO:0034329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034329", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "establishment of epithelial cell apical/basal polarity", "id": "GO:0045198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045198", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "cerebral cortex neuron differentiation", "id": "GO:0021895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021895", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "negative regulation of proteasomal protein catabolic process", "id": "GO:1901799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901799", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "cell morphogenesis involved in neuron differentiation", "id": "GO:0048667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048667", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "cerebellar granule cell differentiation", "id": "GO:0021707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021707", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "regulation of postsynaptic neurotransmitter receptor internalization", "id": "GO:0099149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099149", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "regulation of synaptic transmission, glutamatergic", "id": "GO:0051966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051966", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" }, { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R782", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R782-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 803, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R782-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R782" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 265, "end_pos": 369, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R782" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 381, "end_pos": 565, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 700 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 437, "end_pos": 439 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 52, "end_pos": 54 }, { "start_pos": 621, "end_pos": 623 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RBW0-1", "uniprot_ac": "A0A5G2RBW0", "uniprot_id": "A0A5G2RBW0_PIG", "mass": { "chemical_mass": 61232.0, "monoisotopic_mass": 61232.0 }, "refseq": {}, "gene_names": [ { "name": "ANTXR1", "type": "recommended", "evidence": [ { "id": "A0A5G2RBW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ] } ], "protein_names": [ { "name": "Anthrax toxin receptor 1", "type": "recommended", "evidence": [ { "id": "A0A5G2RBW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton and thereby plays an important role in normal extracellular matrix (ECM) homeostasis. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. May also act as a receptor for PLAU. Upon ligand binding, stimulates the phosphorylation of EGFR and ERK1/2.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FI72", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI72#function" }, { "database": "UniProtKB", "id": "ARBA00093334", "url": "https://www.uniprot.org/uniprotkb/ARBA00093334#function" }, { "database": "UniProtKB", "id": "A0A287AW61", "url": "https://www.uniprot.org/uniprotkb/A0A287AW61#function" }, { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0#function" }, { "database": "UniProtKB", "id": "A0A8W4F700", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F700#function" }, { "database": "UniProtKB", "id": "F1SPM5", "url": "https://www.uniprot.org/uniprotkb/F1SPM5#function" }, { "database": "UniProtKB", "id": "A0A5G2QR59", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR59#function" }, { "database": "UniProtKB", "id": "A0A287A688", "url": "https://www.uniprot.org/uniprotkb/A0A287A688#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ANTXR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0", "locus": { "chromosome": "3", "start_pos": 73157747, "end_pos": 73398379, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008340", "url": "https://www.ensembl.org/id/ENSSSCG00000008340" } ] } } ], "crossref": [ { "id": "A0A5G2RBW0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBW0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008340", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008340", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01474", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01474", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16059", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16059", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16059:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16059:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05586", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05586", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05587", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05587", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287A688", "url": "https://www.uniprot.org/uniprotkb/A0A287A688", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A688-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A688-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AW61", "url": "https://www.uniprot.org/uniprotkb/A0A287AW61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AW61-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AW61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QR59", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QR59-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWM0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F700", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F700", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F700-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F700-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI72", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SPM5", "url": "https://www.uniprot.org/uniprotkb/F1SPM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SPM5-1", "url": "https://www.uniprot.org/uniprotkb/F1SPM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATVEQKALGIGFKCLSLATFVLICAGQGGRREEGGPACYGGFDLYFILDNLEAKWHSAVFGSALIELLFLSSPQLRMSFIVFSTQGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTASVIIALTDGELHEELFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINESVTLNEKPFTVEDTYLLCPAPILKEVGMNAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVVSAPSSEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVKNNPPAKYPLNNAYHTTSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSILPPPPQAPPPNRAPPPSRPPPRPSV", "length": 554, "header": "tr|A0A5G2RBW0-1|A0A5G2RBW0_PIG Isoform 1 of Anthrax toxin receptor 1 OS=Sus scrofa OX=9823 GN=ANTXR1 PE=1 SV=1 CANONICAL=A0A5G2RBW0-1" }, "isoforms": [ { "isoform_ac": "A0A287A688-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0/entry#A0A287A688-1", "sequence": { "sequence": "MLHHWNEIYYFVEQLAHKFISPQLRMSFIVFSTQGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTASVIIALTDGELHEELFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINESVTLNEKPFTVEDTYLLCPAPILKEVGMNAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAEESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVKNNPPAKYPLNNAYHTTSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSILPPPPQAPPPNRAPPPSRPPPRPSV", "length": 510, "header": "tr|A0A287A688-1|A0A5G2RBW0_PIG Computationally mapped isoform of Anthrax toxin receptor 1 OS=Sus scrofa OX=9823 GN=ANTXR1 PE=1 SV=2 CANONICAL=A0A5G2RBW0-1" }, "locus": { "chromosome": "3", "start_pos": 73397999, "end_pos": 73161356, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049612.2", "url": "https://www.ensembl.org/id/ENSSSCT00000049612.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039458.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039458.2" } ] } }, { "isoform_ac": "A0A287AW61-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0/entry#A0A287AW61-1", "sequence": { "sequence": "MATVEQKALGIGFKCLSLATFVLICAGQGGRREEGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHKFISPQLRMSFIVFSTQGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTASVIIALTDGELHEELFFYSERELARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINESVTLNEKPFTVEDTYLLCPAPILKEVGMNAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAEESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVKNNPPAKYPLNNAYHTTSPPPAPIYTPPPPAPHCPPPPPSAPTPPLGRRRLCGVRTRLSS", "length": 524, "header": "tr|A0A287AW61-1|A0A5G2RBW0_PIG Computationally mapped isoform of Anthrax toxin receptor 1 OS=Sus scrofa OX=9823 GN=ANTXR1 PE=1 SV=2 CANONICAL=A0A5G2RBW0-1" }, "locus": { "chromosome": "3", "start_pos": 73397971, "end_pos": 73161272, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054445.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054445.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048146.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048146.2" } ] } }, { "isoform_ac": "A0A5G2QR59-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0/entry#A0A5G2QR59-1", "sequence": { "sequence": "MATVEQKALGIGFKCLSLATFVLICAGQGGRREEGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHKFISPQLRMSFIVFSTQGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTASVIIALTDGELHEELFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINESVTLNEKPFTVEDTYLLCPAPILKEVGMNAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAEESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVKNNPPAKYPLNNAYHTTSPPPAPISPTPPIPSPPSILPPPPQAPPPNRAPPPSRPPPRPSV", "length": 548, "header": "tr|A0A5G2QR59-1|A0A5G2RBW0_PIG Computationally mapped isoform of Anthrax toxin receptor 1 OS=Sus scrofa OX=9823 GN=ANTXR1 PE=1 SV=2 CANONICAL=A0A5G2RBW0-1" }, "locus": { "chromosome": "3", "start_pos": 73397971, "end_pos": 73161356, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075243.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075243.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066537.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066537.2" } ] } }, { "isoform_ac": "A0A5G2QWM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0/entry#A0A5G2QWM0-1", "sequence": { "sequence": "MATVEQKALGIGFKCLSLATFVLICAGQGGRREEGGPACYGGFDLYFILDNLEAKWHSAVFGSALIELLFLSSPQLRMSFIVFSTQGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTASVIIALTDGELHEELFFYSEREVSDGKCLTWKQGFFLLKRAILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINESVTLNEKPFTVEDTYLLCPAPILKEVGMNAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVVSAPSSEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVKNNPPAKYPLNNAYHTTSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSILPPPPQAPPPNRAPPPSRPPPRPSV", "length": 523, "header": "tr|A0A5G2QWM0-1|A0A5G2RBW0_PIG Computationally mapped isoform of Anthrax toxin receptor 1 OS=Sus scrofa OX=9823 GN=ANTXR1 PE=1 SV=1 CANONICAL=A0A5G2RBW0-1" }, "locus": { "chromosome": "3", "start_pos": 73397971, "end_pos": 73161356, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070759.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070759.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066339.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066339.1" } ] } }, { "isoform_ac": "A0A5G2RBW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0/entry#A0A5G2RBW0-1", "sequence": { "sequence": "MATVEQKALGIGFKCLSLATFVLICAGQGGRREEGGPACYGGFDLYFILDNLEAKWHSAVFGSALIELLFLSSPQLRMSFIVFSTQGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTASVIIALTDGELHEELFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINESVTLNEKPFTVEDTYLLCPAPILKEVGMNAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVVSAPSSEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVKNNPPAKYPLNNAYHTTSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSILPPPPQAPPPNRAPPPSRPPPRPSV", "length": 554, "header": "tr|A0A5G2RBW0-1|A0A5G2RBW0_PIG Isoform 1 of Anthrax toxin receptor 1 OS=Sus scrofa OX=9823 GN=ANTXR1 PE=1 SV=1 CANONICAL=A0A5G2RBW0-1" }, "locus": { "chromosome": "3", "start_pos": 73397971, "end_pos": 73161356, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077889.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077889.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074508.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074508.1" } ] } }, { "isoform_ac": "A0A8W4F700-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0/entry#A0A8W4F700-1", "sequence": { "sequence": "MATVEQKALGIGFKCLSLATFVLICAGQGGRREEGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHKFISPQLRMSFIVFSTQGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTASVIIALTDGELHEELFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINESVTLNEKPFTVEDTYLLCPAPILKEVGMNAALQVSMNDGLSFISSSVIITTTHCDDLWFLVPLERAEDHRSIRMPIQDVKCC", "length": 345, "header": "tr|A0A8W4F700-1|A0A5G2RBW0_PIG Computationally mapped isoform of Anthrax toxin receptor 1 OS=Sus scrofa OX=9823 GN=ANTXR1 PE=1 SV=1 CANONICAL=A0A5G2RBW0-1" }, "locus": { "chromosome": "3", "start_pos": 73397971, "end_pos": 73271672, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099694.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099694.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074963.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074963.1" } ] } }, { "isoform_ac": "A0A8W4FI72-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0/entry#A0A8W4FI72-1", "sequence": { "sequence": "VLHHWNEIYYFVEQLAHKFISPQLRMSFIVFSTQGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTASVIIALTDGELHEELFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINESVTLNEKPFTVEDTYLLCPAPILKEVGMNAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAEESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVKNNPPAKYPLNNAYHTTSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSILPPPPQAPPPNRAPPPSRPPPRPSV", "length": 510, "header": "tr|A0A8W4FI72-1|A0A5G2RBW0_PIG Computationally mapped isoform of Anthrax toxin receptor 1 OS=Sus scrofa OX=9823 GN=ANTXR1 PE=1 SV=1 CANONICAL=A0A5G2RBW0-1" }, "locus": { "chromosome": "3", "start_pos": 73373202, "end_pos": 73161356, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097093.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097093.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078923.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078923.1" } ] } }, { "isoform_ac": "F1SPM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0/entry#F1SPM5-1", "sequence": { "sequence": "MATVEQKALGIGFKCLSLATFVLICAGQGGRREEGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHKFISPQLRMSFIVFSTQGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTASVIIALTDGELHEELFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINESVTLNEKPFTVEDTYLLCPAPILKEVGMNAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVVSAPSSEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTSSRIHSVEESQPAVGCPRAPPSSPNMPITTPPRPDVRFRNRLGIPHDPSPFIFKVRKQVQKGSRDTFKHLFLFAPHHHLTHLPFAYLEV", "length": 559, "header": "tr|F1SPM5-1|A0A5G2RBW0_PIG Computationally mapped isoform of Anthrax toxin receptor 1 OS=Sus scrofa OX=9823 GN=ANTXR1 PE=1 SV=3 CANONICAL=A0A5G2RBW0-1" }, "locus": { "chromosome": "3", "start_pos": 73397971, "end_pos": 73198313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009134.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009134.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008903.4", "url": "https://www.ensembl.org/id/ENSSSCP00000008903.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 520, "start_aa": "Thr", "end_pos": 520, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr520", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SPM5", "url": "https://www.uniprot.org/uniprotkb/F1SPM5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" }, { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" }, { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "lamellipodium membrane", "id": "GO:0031258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031258", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" }, { "name": "filopodium membrane", "id": "GO:0031527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031527", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" }, { "name": "positive regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0045742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045742", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RBW0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 554, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RBW0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBW0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RBW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBW0" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 213, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A5G2QR59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR59#function" }, { "id": "A0A5G2QR59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR59" }, { "id": "PIRSR038023-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038023-1" } ], "binding_site_uniprot": 118, "amino_acid": "Met", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 118, "end_pos": 118, "start_aa": "Met", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QR59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR59#function" }, { "id": "A0A5G2QR59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR59" }, { "id": "PIRSR038023-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038023-1" } ], "binding_site_uniprot": 52, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 52, "end_pos": 52, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QR59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR59#function" }, { "id": "A0A5G2QR59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR59" }, { "id": "PIRSR038023-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038023-1" } ], "binding_site_uniprot": 54, "amino_acid": "Ala", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 54, "end_pos": 54, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 520 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 473, "end_pos": 475 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RD86-1", "uniprot_ac": "A0A5G2RD86", "uniprot_id": "A0A5G2RD86_PIG", "mass": { "chemical_mass": 70323.0, "monoisotopic_mass": 70323.0 }, "refseq": { "ac": "XP_005653924", "name": "signal recognition particle subunit SRP68", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653924" }, "gene_names": [ { "name": "SRP68", "type": "recommended", "evidence": [ { "id": "A0A5G2RD86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ] }, { "name": "SRP68", "type": "synonym", "evidence": [ { "id": "XP_005653924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653924" } ] } ], "protein_names": [ { "name": "Signal recognition particle subunit SRP68", "type": "recommended", "evidence": [ { "id": "A0A5G2RD86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86/entry#names_and_taxonomy" } ] }, { "name": "SRP68", "type": "synonym", "evidence": [ { "id": "A0A5G2RD86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86/entry#names_and_taxonomy" } ] }, { "name": "signal recognition particle subunit SRP68", "type": "synonym", "evidence": [ { "id": "XP_005653924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653924" } ] } ], "function": [ { "annotation": "Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86#function" }, { "database": "UniProtKB", "id": "PIRNR038995", "url": "https://www.uniprot.org/uniprotkb/PIRNR038995#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SRP68", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86", "locus": { "chromosome": "12", "start_pos": 5406347, "end_pos": 5367863, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017191", "url": "https://www.ensembl.org/id/ENSSSCG00000017191" } ] } } ], "crossref": [ { "id": "A0A5G2RD86", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RD86", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017191", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017191", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15481", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15481", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100739290", "url": "https://www.ncbi.nlm.nih.gov/gene/100739290", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100739290", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739290", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DERFIHI", "url": "https://omabrowser.org/oma/group/DERFIHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RD86", "url": "https://www.orthodb.org/?gene=A0A5G2RD86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12860:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12860:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005653924", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653924", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R2C4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RD86-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW08", "url": "https://www.uniprot.org/uniprotkb/F1RW08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW08-1", "url": "https://www.uniprot.org/uniprotkb/F1RW08-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEKQVPGGGGGSSGGGGGGSSGGGRGAGGEENKENERPSAGSKANKEFGDSLSLEILQIIKESQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNFKMGNRHKFTGKKVTEDLLTDNRYLLLVLMDAERAWSYAMQLKQEANTEPRKRFHLLSRLRKAVKHAEELERLCESNRVDAKTKLEAQAYTAYLSGMLRFEHQEWKAAIEAFNKCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIGDQSAINELMQMRLRSGGTEGLLAEKLEALITQTRAKQAATMSEVEWRGRAVPVKVDRVRIFLLGLADNEAAIAQAESEETKERLFESMLSECRDAIQAVREELKPDQKQRDYPLDGESGKVSNLQYLHSYLTYIKLSTAIKRNENMARGLQKALLQQQPEDDGKRSPRPQDLIRLYDIILQNLVELLQLPGLEEDRAFQKEIGLKTLVYKAYRCFFIAQSYVLVKKWSEALVLYDRVLKYADEVNSDAGAFKNSLKDLPDVLELISQVRSEKCCLQAAAILDTNDPQQTETSSQVKDNKPLVERFETFCLDPSLVTKQANLVHFPPGFQPVPCKPLFFDLALNHVAFPPLEDKLEQKTKSGLAGYIKGIFGFRS", "length": 622, "header": "tr|A0A5G2RD86-1|A0A5G2RD86_PIG Isoform 1 of Signal recognition particle subunit SRP68 OS=Sus scrofa OX=9823 GN=SRP68 PE=1 SV=1 CANONICAL=A0A5G2RD86-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R2C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86/entry#A0A5G2R2C4-1", "sequence": { "sequence": "MQGCRNWEAIPRSSLHPWWTGNGMVTRRRQKLRPACASGPSSLARRQWSMGIGAHAQAHSNKWPLPEGRTGGGGVRRYPISPSAPVPLSPSRVVPPPLSQPALRRGGKMAAEKQVPGGGGGSSGGGGGGSSGGGRGAGGEENKENERPSAGSKANKEFGDSLSLEILQIIKESQQQHGLRHGDFQRYRYLLLVLMDAERAWSYAMQLKQEANTEPRKRFHLLSRLRKAVKHAEELERLCESNRVDAKTKLEAQAYTAYLSGMLRFEHQEWKAAIEAFNKCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIGDQSAINELMQMRLRSGGTEGLLAEKLEALITQTRAKQAATMSEVEWRGRAVPVKVDRVRIFLLGLADNEAAIAQAESEETKERLFESMLSECRDAIQAVREELKPDQKQRDYPLDGESGKVSNLQYLHSYLTYIKLSTAIKRNENMARGLQKALLQQQPEDDGKRSPRPQDLIRLYDIILQNLVELLQLPGLEEDRAFQKEIGLKTLVYKAYRCFFIAQSYVLVKKWSEALVLYDRVLKYADEVNSDAGAFKNSLKDLPDVLELISQVRSEKCCLQAAAILDTNDPQQTETSSQVKDNKPLVERFETFCLDPSLVTKQANLVHFPPGFQPVPCKPLFFDLALNHVAFPPLEDKLEQKTKSGLAGYIKGIFGFRS", "length": 692, "header": "tr|A0A5G2R2C4-1|A0A5G2RD86_PIG Computationally mapped isoform of Signal recognition particle subunit SRP68 OS=Sus scrofa OX=9823 GN=SRP68 PE=1 SV=2 CANONICAL=A0A5G2RD86-1" }, "locus": { "chromosome": "12", "start_pos": 5401927, "end_pos": 5368064, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079154.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079154.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071254.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071254.2" } ] } }, { "isoform_ac": "A0A5G2RD86-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86/entry#A0A5G2RD86-1", "sequence": { "sequence": "MAAEKQVPGGGGGSSGGGGGGSSGGGRGAGGEENKENERPSAGSKANKEFGDSLSLEILQIIKESQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNFKMGNRHKFTGKKVTEDLLTDNRYLLLVLMDAERAWSYAMQLKQEANTEPRKRFHLLSRLRKAVKHAEELERLCESNRVDAKTKLEAQAYTAYLSGMLRFEHQEWKAAIEAFNKCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIGDQSAINELMQMRLRSGGTEGLLAEKLEALITQTRAKQAATMSEVEWRGRAVPVKVDRVRIFLLGLADNEAAIAQAESEETKERLFESMLSECRDAIQAVREELKPDQKQRDYPLDGESGKVSNLQYLHSYLTYIKLSTAIKRNENMARGLQKALLQQQPEDDGKRSPRPQDLIRLYDIILQNLVELLQLPGLEEDRAFQKEIGLKTLVYKAYRCFFIAQSYVLVKKWSEALVLYDRVLKYADEVNSDAGAFKNSLKDLPDVLELISQVRSEKCCLQAAAILDTNDPQQTETSSQVKDNKPLVERFETFCLDPSLVTKQANLVHFPPGFQPVPCKPLFFDLALNHVAFPPLEDKLEQKTKSGLAGYIKGIFGFRS", "length": 622, "header": "tr|A0A5G2RD86-1|A0A5G2RD86_PIG Isoform 1 of Signal recognition particle subunit SRP68 OS=Sus scrofa OX=9823 GN=SRP68 PE=1 SV=1 CANONICAL=A0A5G2RD86-1" }, "locus": { "chromosome": "12", "start_pos": 5401927, "end_pos": 5368388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090324.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090324.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072313.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072313.1" } ] } }, { "isoform_ac": "F1RW08-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86/entry#F1RW08-1", "sequence": { "sequence": "MQGCRNWEAIPRSSLHPWWTGNGMVTRRRQKLRPACASGPSSLARRQWSMGIGAHAQAHSNKWPLPEGRTGGGGVRRYPISPSAPVPLSPSRVVPPPLSQPALRRGGKMAAEKQVPGGGGGSSGGGGGGSSGGGRGAGGEENKENERPSAGSKANKEFGDSLSLEILQIIKESQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNFKMGNRHKFTGKKVTEDLLTDNRYLLLVLMDAERAWSYAMQLKQEANTEPRKRFHLLSRLRKAVKHAEELERLCESNRVDAKTKLEAQAYTAYLSGMLRFEHQEWKAAIEAFNKCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIGDQSAINELMQMRLRSGGTEGLLAEKLEALITQTRAKQAATMSEVEWRGRAVPVKVDRVRIFLLGLADNEAAIAQAESEETKERLFESMLSECRDAIQAVREELKPDQKQRDYPLDGESGKVSNLQYLHSYLTYIKLSTAIKRNENMARGLQKALLQQQPEDDGKRSPRPQDLIRLYDIILQNLVELLQLPGLEEDRAFQKEIGLKTLVYKAYRCFFIAQSYVLVKKWSEALVLYDRVLKYADEVNSDAGAFKNSLKDLPDVLELISQVRSEKCCLQAAAILDTNDPQQTETSSQVKDNKPLVERFETFCLDPSLVTKQANLVHFPPGFQPVPCKPLFFDLALNHVAFPPLEDKLEQKTKSGLAGYIKGIFGFRS", "length": 730, "header": "tr|F1RW08-1|A0A5G2RD86_PIG Computationally mapped isoform of Signal recognition particle subunit SRP68 OS=Sus scrofa OX=9823 GN=SRP68 PE=1 SV=4 CANONICAL=A0A5G2RD86-1" }, "locus": { "chromosome": "12", "start_pos": 5401927, "end_pos": 5368064, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018716.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018716.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018214.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018214.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RW08", "url": "https://www.uniprot.org/uniprotkb/F1RW08" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100739290", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739290", "resource": "KEGG Pathway" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G2B2-1", "protein_name": "Signal recognition particle subunit SRP68", "gene_name": "Srp68", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWNVETQLSHQLNPGRAGAHQHTAKAREKNEAESVSVPSTRPGRCRSLPLLVVSPPPSHPALRLRGKMAAEKQIPGGGSGGGGSGGGGGGGGSGGGRSAGGDENKENERPSAGSKANKEFGDSLSLEILQVIKESQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNFKMGNRHKFTGKKVTEELLTDSRYLLLVLMDAERAWSYAMQLKQEANTEPRKRFHLLSRLRKAVKHAEELERLCESSRVDAKTKLEAQAYTAYLSGMLRFEHQEWKAAIEAFNRCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIGDQSAINELMQMRLRSGGTEGLLAEKLEALITQTRAKQAATMSEVEWRGRTVPVKIDKVRIFLLGLADNEAAIVQAESEETKERLFESMLSECRDALQAVREELKPDQKQRDYTVDGESGKVSNLQYLHSYLTYIKLSTAIRRNENMAKGLHRALLQQQPEDDSKRSPRPQDLIRLYDIILQNLVELLQLPGLEEDRTFQKEIGLKTLVFKAYRCFFIAQSYVLVKKWSEALVLYDRVLKYASEVSSHGGAFKNSLKDLPDVQELITQVRSEKCSLQAAAILDANESHQTDTASQVKDNTPLVERFETFCLDPSLVTKQASLVHFPPGFQPIPCKPLFFDLALNHVAFPPLEDKLEQKTKSGLTGYIKGIFGFRS", "length": 693 }, "evidence": [ { "id": "A0A5G2RD86", "url": "https://omabrowser.org/oma/group/A0A5G2RD86/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1ZXE8-1", "protein_name": "Signal recognition particle subunit SRP68", "gene_name": "srp68", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATNISTSPKEDVPKEKFHLDILNFSQTSQIQFGLRLQDYKKYRQYCSKRIQRLRSQLRKQYGKKNYVNKIVLNGGETEKQINDVRYLQISLLKTERAWSYAMDLKAQFEKDNDSRIGFHMNRRFGKASRNSTQLYELCKLVADQYTIIEAHAYSSWMASSLSLTKQDFKKALEEINISKTIYEKLSEQGDHSQKELYQKRIEETEPIIRFCLYNLKNEKNTSNKVSQNTLTIIEQSLEELKNQENKKKSSTSSTTTTTATTTIEWKSKSIKVDEKLDEKLKIFNEFKKENENKLPKNINASIDTTSNISPIFNIYDKLVYNLINCETIVKNDLSTLVRVNLKNKSVKSEIEEQSTRILLAYIMYHKMKYLYERNSILITMMQRVLDGEKVDESAIKKKVKKVTWNDLVRLSTHQVKVYTIMSESRDTDSNKEIARDQDAQLILLKSIRLYYIAVCLAKSLKFSETMAVLDRVLTNIQNVRKTNTKNQQILNDTNELESNIKKQRSQIHANSFIQQLSENQDLKNQMSSLSIGGITTASGKSNDLISGLDSFDTSFLTEKKLVQLPPQLQPVQAKPIFFDLAFNSVTFPSLDQRKKGSSTGTPSKGLFGFWGRG", "length": 614 }, "evidence": [ { "id": "A0A5G2RD86", "url": "https://omabrowser.org/oma/group/A0A5G2RD86/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BMA6-1", "protein_name": "Signal recognition particle subunit SRP68", "gene_name": "Srp68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAEKQIPGGGSGGGGSGSGGGGGGSGGGRSAGGDENKENERPSAGSKANKEFGDSLSLEILQIIKESQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNFKMGNRHKFTGKKVTEELLTDNRYLLLVLMDAERAWSYAMQLKQEANTEPRKRFHLLSRLRKAVKHAEELERLCESNRVDAKTKLEAQAYTAYLSGMLRFEHQEWKSAIEAFNKCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIGDQSAINELMQMRLRSGGTEGLLAEKLEALITQTRAKQAATMSEVEWRGRTVPVKIDKVRIFLLGLADNEAAIVQAESEETKERLFESMLSECRDALQAVREELKPDQKQRDYALDGESGKVSNLQYLHSYLTYIKLSTAIRRNENMAKGLHRALLQQQPEDDSKRSPRPQDLIRLYDIILQNLVELLQLPGLEEDRTFQKEISLKTLVFKAYRCFFIAQSYVLVKKWSEALVLYDRVLKYANEVSSHGGASKNSLKDLPDVQELITQVRSEKCSLQAAAILDANDSHQTDTSSQVKDNTPLVERFESFCLDPSLVTKQANLVHFPPGFQPIPCKPLFFDLALNHVAFPPLEDKLEQKTKSGLTGYIKGIFGFRS", "length": 625 }, "evidence": [ { "id": "A0A5G2RD86", "url": "https://omabrowser.org/oma/group/A0A5G2RD86/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FH46-1", "protein_name": "Signal recognition particle subunit SRP68", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGKKQSEISAMEIDDPKSESSDQILPRFSINVLQLMKSSQAQHGLRHGDYARYRRYCSARLRRLYKSLKFTHGRGKYTRRAILESTVTDVRFLHVVFYMAERAWSHAMEKRQLPDGPNARQRIYLVGRLRKAVKWASLFSSLCSIKTDSRTSLEAEAYASYMKGTLLFEQDQNWETGLACFKNARAVYEELGKYGDLENQVLCRERVEELEPSIRYCLHKIGKSNLQTSELLQIGEMEGPALDLFKAKIEAAMEEARSQQAASLTEFSWLGYRFPVSNPKSRVSILKAQELEKELQSPTAESLPAEKKLTIFDKLFTAYHDARNTIRSDLVSAGNAESVKDDLNGLDKAVGAVLGQRTIERNQLLVKVAKSKLNRKRDDKNDKVTRPEELVRLYDLLLQNVADLSDLISSGRDRKPEEIAFEEECQRTSLAFRAERCFYLAKSYSLAGKRAEAFALYSRARSLAEDALNKFQSIAKKDEGTIQELKTLIKECRANSCIEHATGIMEEERAPENLSNRMSTISLNNTAAQVEEKYLLDKLDVYESAVGDSNTKTAPKIERFPPALQSIPRNPIVLDLAYNCIDFPVIENRMKKKGGFFSSRISSLW", "length": 605 }, "evidence": [ { "id": "A0A5G2RD86", "url": "https://omabrowser.org/oma/group/A0A5G2RD86/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UHB9-1", "protein_name": "Signal recognition particle subunit SRP68", "gene_name": "SRP68", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAEKQVPGGGGGGGSGGGGGSGGGGSGGGRGAGGEENKENERPSAGSKANKEFGDSLSLEILQIIKESQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNFKMGNRHKFTGKKVTEELLTDNRYLLLVLMDAERAWSYAMQLKQEANTEPRKRFHLLSRLRKAVKHAEELERLCESNRVDAKTKLEAQAYTAYLSGMLRFEHQEWKAAIEAFNKCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIGDQSAINELMQMRLRSGGTEGLLAEKLEALITQTRAKQAATMSEVEWRGRTVPVKIDKVRIFLLGLADNEAAIVQAESEETKERLFESMLSECRDAIQVVREELKPDQKQRDYILEGEPGKVSNLQYLHSYLTYIKLSTAIKRNENMAKGLQRALLQQQPEDDSKRSPRPQDLIRLYDIILQNLVELLQLPGLEEDKAFQKEIGLKTLVFKAYRCFFIAQSYVLVKKWSEALVLYDRVLKYANEVNSDAGAFKNSLKDLPDVQELITQVRSEKCSLQAAAILDANDAHQTETSSSQVKDNKPLVERFETFCLDPSLVTKQANLVHFPPGFQPIPCKPLFFDLALNHVAFPPLEDKLEQKTKSGLTGYIKGIFGFRS", "length": 627 }, "evidence": [ { "id": "A0A5G2RD86", "url": "https://omabrowser.org/oma/group/A0A5G2RD86/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VSS2-1", "protein_name": "Signal recognition particle subunit SRP68", "gene_name": "Srp68", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVVQEDNPNTGDVQEKTETAPVAEPSKIFTVEILHMIKDAQQQHGLRHGDFQRYRGYCSRRIRRLRKALKYPQGDKRHFKRRDVTIGQLTGKKADERFIHIPLICAERAWAYAMQLKQESNTEPRKRFHLVNKLRRACFYALQLQELCNTEAFDARTKLECEAYVAWMHGTLHFELQLWKTAGEHLKRAQVVYENLGKALPEDEQELYRAKVNEFTPNLRYCAYNISGGASGGKIDEILELRAQGVLENLDVLVSQTKTESSEGLQTIDWRGRKVTVRPEKVRLFLLSAQELDKSLAKTTKQDAKIELIERILMDCKDAIQAVRDEIKQDPKLRSLTTGQTVSGVQYLLAYLSYIRHSRTLQRNLCLVEQAKLNFYDPNLQSQQNVGDGKRVRPQDLARLYEIILQNVTEMQQINGLEDDATYQSEVENLAITFKAFRCYYIALTLIDIKKWKEAVALYERASNYATEALKGKSSPEFQLQEELKKVVSAIDGCKFSAHAYSVLEDDNSEESGTTTKSQKTTKPLYERLSLYKEDQSLHTKAPNVFKLTPDMEPIPCKPIFFDLAMTYVELPSLEGKLESPGKKGASITGFVKGFLGWGGGGNK", "length": 604 }, "evidence": [ { "id": "A0A5G2RD86", "url": "https://omabrowser.org/oma/group/A0A5G2RD86/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "signal recognition particle binding", "id": "GO:0005047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005047", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ], "pmid": "" }, { "name": "endoplasmic reticulum signal peptide binding", "id": "GO:0030942", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030942", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ], "pmid": "" }, { "name": "7S RNA binding", "id": "GO:0008312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008312", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "signal recognition particle, endoplasmic reticulum targeting", "id": "GO:0005786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005786", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RD86-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 622, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RD86-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RD86" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RC81-1", "uniprot_ac": "A0A5G2RC81", "uniprot_id": "A0A5G2RC81_PIG", "mass": { "chemical_mass": 74771.0, "monoisotopic_mass": 74771.0 }, "refseq": {}, "gene_names": [ { "name": "ABCG8", "type": "recommended", "evidence": [ { "id": "A0A5G2RC81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ] } ], "protein_names": [ { "name": "ATP-binding cassette sub-family G member 8", "type": "recommended", "evidence": [ { "id": "A0A5G2RC81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81/entry#names_and_taxonomy" } ] }, { "name": "Sterolin-2", "type": "synonym", "evidence": [ { "id": "A0A5G2RC81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ABCG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81", "locus": { "chromosome": "3", "start_pos": 96596531, "end_pos": 96616229, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008453", "url": "https://www.ensembl.org/id/ENSSSCG00000008453" } ] } } ], "crossref": [ { "id": "A0A5G2RC81", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC81", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008453", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008453", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48041", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48041", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48041:SF71", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48041:SF71", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1369062", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1369062", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RC81-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5I9", "url": "https://www.uniprot.org/uniprotkb/F1S5I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5I9-1", "url": "https://www.uniprot.org/uniprotkb/F1S5I9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEEALKETGLGKRAAPQDDSGLQDSVFSSESDNSLYFTYSGQSNTLEVRGLTYQVDMASQVPWFEQLAHFKMPWTSHKDSCELGLQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGPGGKIKSGQIWINGQPSTPQLVRKYVAHVRQHDQLLPNLTVRETLAFVAQLRLPRTFSQAQRDKRVDDVIAELRLRQCANTRVGNTYIRGVSGGERRRVSIAVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISIHQPRSDIFRLFDLVLLMTSGTTIYLGAAQHMVQYFTSAGHPCPRYSNPADFYVDLTSIDRRSREQEVATREKAQSLAALFQEKVRGFDDFLWTAEPRAQGVSPCVQSSPASRSDTNAFQTPTKLPPILQFATLIRRQISNDFRDLPTLLIHGVEACLMSLIIGFLYYGYGAIKVSFMDMSALLFMIGALVPFNVILDVISKCHSERALLYHELEDGLYTAGPYFFAKILGGLPEHCVYIIIYGMPTYLLTDLRPGLEPFLLHFMLVWLVVFCCRMMALATAALLPTFHMSSFFGNALYNSFYLTGGFMISLDNLWIVPALISKVSFLRWCFEGLMKIQLGGLTYHMAAGNLTIPIPGDAILNAMGLNSYPLYAIYLIVIGISGGFMVLYYISLRFIKKSTQDW", "length": 670, "header": "tr|A0A5G2RC81-1|A0A5G2RC81_PIG Isoform 1 of ATP-binding cassette sub-family G member 8 OS=Sus scrofa OX=9823 GN=ABCG8 PE=3 SV=1 CANONICAL=A0A5G2RC81-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RC81-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81/entry#A0A5G2RC81-1", "sequence": { "sequence": "MAEEALKETGLGKRAAPQDDSGLQDSVFSSESDNSLYFTYSGQSNTLEVRGLTYQVDMASQVPWFEQLAHFKMPWTSHKDSCELGLQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGPGGKIKSGQIWINGQPSTPQLVRKYVAHVRQHDQLLPNLTVRETLAFVAQLRLPRTFSQAQRDKRVDDVIAELRLRQCANTRVGNTYIRGVSGGERRRVSIAVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISIHQPRSDIFRLFDLVLLMTSGTTIYLGAAQHMVQYFTSAGHPCPRYSNPADFYVDLTSIDRRSREQEVATREKAQSLAALFQEKVRGFDDFLWTAEPRAQGVSPCVQSSPASRSDTNAFQTPTKLPPILQFATLIRRQISNDFRDLPTLLIHGVEACLMSLIIGFLYYGYGAIKVSFMDMSALLFMIGALVPFNVILDVISKCHSERALLYHELEDGLYTAGPYFFAKILGGLPEHCVYIIIYGMPTYLLTDLRPGLEPFLLHFMLVWLVVFCCRMMALATAALLPTFHMSSFFGNALYNSFYLTGGFMISLDNLWIVPALISKVSFLRWCFEGLMKIQLGGLTYHMAAGNLTIPIPGDAILNAMGLNSYPLYAIYLIVIGISGGFMVLYYISLRFIKKSTQDW", "length": 670, "header": "tr|A0A5G2RC81-1|A0A5G2RC81_PIG Isoform 1 of ATP-binding cassette sub-family G member 8 OS=Sus scrofa OX=9823 GN=ABCG8 PE=3 SV=1 CANONICAL=A0A5G2RC81-1" }, "locus": { "chromosome": "3", "start_pos": 96616104, "end_pos": 96598587, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069275.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069275.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068229.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068229.1" } ] } }, { "isoform_ac": "F1S5I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81/entry#F1S5I9-1", "sequence": { "sequence": "MAEEALKETGLGKRAAPQDDSGLQDSVFSSESDNSLYFTYSGQSNTLEVRGLTYQVDMASQVPWFEQLAHFKMPWTSHKDSCELGLQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGPGGKIKSGQIWINGQPSTPQLVDDVIAELRLRQCANTRVGNTYIRGVSGGERRRVSIAVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISIHQPRSDIFRLFDLVLLMTSGTTIYLGAAQHMVQYFTSAGHPCPRYSNPADFYVDLTSIDRRSREQEVATREKAQSLAALFQEKVRGFDDFLWTAEPRAQGVSPCVQSPASRSDTNAFQTPTKLPPILQFATLIRRQISNDFRDLPTLLIHGVEACLMSLIIGFLYYGYGAIKVSFMDMSALLFMIGALVPFNVILDVISKCHSERALLYHELEDGLYTAGPYFFAKILGGLPEHCVYIIIYGMPTYLLTDLRPGLEPFLLHFMLVWLVVFCCRMMALATAALLPTFHMSSFFGNALYNSFYLTGGFMISLDNLWIVPALISKVSFLRWCFEGLMKIQLGGLTYHMAAGNLTIPIPGDAILNAMGLNSYPLYAIYLIVIGISGGFMVLYYISLRFIKQNLLKTGDSSPDSCRPGGGPKQGLQTACSSSQGVPSQGTRMTREQEAQPPLAHGAALAQAGHRMAVE", "length": 686, "header": "tr|F1S5I9-1|A0A5G2RC81_PIG Computationally mapped isoform of ATP-binding cassette sub-family G member 8 OS=Sus scrofa OX=9823 GN=ABCG8 PE=3 SV=4 CANONICAL=A0A5G2RC81-1" }, "locus": { "chromosome": "3", "start_pos": 96616104, "end_pos": 96598406, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009255.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009255.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009021.5", "url": "https://www.ensembl.org/id/ENSSSCP00000009021.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S5I9", "url": "https://www.uniprot.org/uniprotkb/F1S5I9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1369062", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1369062", "resource": "Reactome", "description": "ABC transporters in lipid homeostasis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "cholesterol transfer activity", "id": "GO:0120020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "ATP-binding cassette (ABC) transporter complex", "id": "GO:0043190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043190", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "negative regulation of intestinal phytosterol absorption", "id": "GO:0010949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010949", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "cholesterol efflux", "id": "GO:0033344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033344", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "negative regulation of intestinal cholesterol absorption", "id": "GO:0045796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045796", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RC81-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 670, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RC81-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC81" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RC81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC81" }, { "id": "PS50893", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 311, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 617, "end_pos": 619 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RBV3-1", "uniprot_ac": "A0A5G2RBV3", "uniprot_id": "A0A5G2RBV3_PIG", "mass": { "chemical_mass": 52195.0, "monoisotopic_mass": 52195.0 }, "refseq": { "ac": "XP_020926912", "name": "uridine 5'-monophosphate synthase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926912" }, "gene_names": [ { "name": "UMPS", "type": "recommended", "evidence": [ { "id": "A0A5G2RBV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3" } ] }, { "name": "UMPS", "type": "synonym", "evidence": [ { "id": "XP_020926912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926912" } ] } ], "protein_names": [ { "name": "Uridine 5'-monophosphate synthase", "type": "recommended", "evidence": [ { "id": "A0A5G2RBV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3/entry#names_and_taxonomy" } ] }, { "name": "2.4.2.10", "type": "synonym", "evidence": [ { "id": "A0A5G2RBV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3/entry#names_and_taxonomy" } ] }, { "name": "4.1.1.23", "type": "synonym", "evidence": [ { "id": "A0A5G2RBV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3/entry#names_and_taxonomy" } ] }, { "name": "uridine 5'-monophosphate synthase", "type": "synonym", "evidence": [ { "id": "XP_020926912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926912" } ] } ], "function": [ { "annotation": "Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine-5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP).", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3#function" }, { "database": "UniProtKB", "id": "ARBA00060327", "url": "https://www.uniprot.org/uniprotkb/ARBA00060327#function" }, { "database": "UniProtKB", "id": "F1SQ55", "url": "https://www.uniprot.org/uniprotkb/F1SQ55#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UMPS", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3", "locus": { "chromosome": "13", "start_pos": 135610058, "end_pos": 135650603, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011864", "url": "https://www.ensembl.org/id/ENSSSCG00000011864" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011864", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011864", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04725", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04725", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06223", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06223", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100516340", "url": "https://www.ncbi.nlm.nih.gov/gene/100516340", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516340", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516340", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SAKHVCG", "url": "https://omabrowser.org/oma/group/SAKHVCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RBV3", "url": "https://www.orthodb.org/?gene=A0A5G2RBV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19278", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19278", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19278:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19278:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00156", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00156", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00215", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00215", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-500753", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-500753", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020926912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926912", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10380", "url": "https://www.rhea-db.org/rhea/10380", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "11596", "url": "https://www.rhea-db.org/rhea/11596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RBV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SQ55", "url": "https://www.uniprot.org/uniprotkb/F1SQ55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SQ55-1", "url": "https://www.uniprot.org/uniprotkb/F1SQ55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAADVALASLVTGLYDVQAFKFGSFVLKSGLSSPVYIDLRGIVSRPRLLSQVAEILFQTAQNAGINFDTVCGVPYTALPLATVICSTNQIPMLIRRKEAKDYGTKRLIEGAVNPGETCLIIEDVVTSGSSILETVEVLQKEGLKVTDAIVVLDREQGGRDKLQAHGIRLHSVCTLSNMLEILEQQKKIDAEMVERVKRFIQENVFVVANHNGSLPSAKKAPKELSFGTRAELPGIHPVASKLLRLMQKKETNLCLSADISESRELLQLADALGPSICMLKTHVDILNDFTPDVMKELTTLAKRHEFLIFEDRKFADIGNTVKKQYAGGVFKIASWADIVNAHVVPGSGVVKGLREVGLPLHRACLLIAEMSSAGSLATGSYTEAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGILMSANRLEAAEKYRKAAWEAYLSRLAV", "length": 480, "header": "tr|A0A5G2RBV3-1|A0A5G2RBV3_PIG Isoform 1 of Uridine 5'-monophosphate synthase OS=Sus scrofa OX=9823 GN=UMPS PE=1 SV=1 CANONICAL=A0A5G2RBV3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RBV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3/entry#A0A5G2RBV3-1", "sequence": { "sequence": "MAAADVALASLVTGLYDVQAFKFGSFVLKSGLSSPVYIDLRGIVSRPRLLSQVAEILFQTAQNAGINFDTVCGVPYTALPLATVICSTNQIPMLIRRKEAKDYGTKRLIEGAVNPGETCLIIEDVVTSGSSILETVEVLQKEGLKVTDAIVVLDREQGGRDKLQAHGIRLHSVCTLSNMLEILEQQKKIDAEMVERVKRFIQENVFVVANHNGSLPSAKKAPKELSFGTRAELPGIHPVASKLLRLMQKKETNLCLSADISESRELLQLADALGPSICMLKTHVDILNDFTPDVMKELTTLAKRHEFLIFEDRKFADIGNTVKKQYAGGVFKIASWADIVNAHVVPGSGVVKGLREVGLPLHRACLLIAEMSSAGSLATGSYTEAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGILMSANRLEAAEKYRKAAWEAYLSRLAV", "length": 480, "header": "tr|A0A5G2RBV3-1|A0A5G2RBV3_PIG Isoform 1 of Uridine 5'-monophosphate synthase OS=Sus scrofa OX=9823 GN=UMPS PE=1 SV=1 CANONICAL=A0A5G2RBV3-1" }, "locus": { "chromosome": "13", "start_pos": 135650568, "end_pos": 135614382, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071965.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071965.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068099.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068099.1" } ] } }, { "isoform_ac": "F1SQ55-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3/entry#F1SQ55-1", "sequence": { "sequence": "MAAADVALASLVTGLYDVQAFKFGSFVLKSGLSSPVYIDLRGIVSRPRLLSQVAEILFQTAQNAGINFDTVCGVPYTALPLATVICSTNQIPMLIRRKEAKDYGTKRLIEGAVNPGETCLIIEDVVTSGSSILETVEVLQKEGLKVTDAIVVLDREQGGRDKLQAHGIRLHSVCTLSNMLEILEQQKKIDAEMVERVKRFIQENVFVVANHNGSLPSAKKAPKELSFGTRAELPGIHPVASKLLRLMQKKETNLCLSADISESRELLQLADALGPSICMLKTHVDILNDFTPDVMKELTTLAKRHEFLIFEDRKFADIGNTVKKQYAGGVFKIASWADIVNAHVVPGSGVVKGLREVGLPLHRACLLIAEMSSAGSLATGSYTEAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGILMSANRLEAAEKYRKAAYNTAWILPWVLDWLLDLTLVYRKYSVMCDHSNPFFFKLSFVEIDID", "length": 516, "header": "tr|F1SQ55-1|A0A5G2RBV3_PIG Computationally mapped isoform of Uridine 5'-monophosphate synthase OS=Sus scrofa OX=9823 GN=UMPS PE=1 SV=5 CANONICAL=A0A5G2RBV3-1" }, "locus": { "chromosome": "13", "start_pos": 135650568, "end_pos": 135614161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012978.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012978.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012636.5", "url": "https://www.ensembl.org/id/ENSSSCP00000012636.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SQ55", "url": "https://www.uniprot.org/uniprotkb/F1SQ55" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516340", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516340", "resource": "KEGG Pathway" }, { "id": "R-SSC-500753", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-500753", "resource": "Reactome", "description": "Pyrimidine biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZCP5-1", "protein_name": "Uridine 5'-monophosphate synthase", "gene_name": "UMPS", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAGGAGRVAAALLEARAVRFGDFVLRSGIASPVYVDLRGLASRPSLLRLVADLLFQTAKDAALQYDCVCGVPYTALPLATIISSENQIPMLIRRKEAKDYGTKRLVEGTINPGETCLIIEDVVTSGSSVLETAEVLRKEGLKVTDAVVLLDREQGGKARLEEHGIRLHSVCTLSGMLDILQQQGEVDVEMVEKVKNFIQGNVFEPGAQNGPTPVKRVCKELSFRARAELPGVHPVAARLLTLMEKKQTNLCLSADVTGSKELLQLAASLGPSICILKTHIDILNDFTQEVVKELRALADQHEFLIFEDRKFADIGNTVKHQYEGGVFKIASWSDVVNAHVVPGSGVVKGLKEVGLPLQRGCLLIAEMSSQGSLATGEYTKAAVQMAEDNPDFVFGFISGSRVSDKPEFLHLTPGVQLQAGGDNLGQKYLSPKEVISEKGSDIIIVGRGILSASDRLQEAEKYRKAAWESYISRLGVHA", "length": 479 }, "evidence": [ { "id": "A0A5G2RBV3", "url": "https://omabrowser.org/oma/group/A0A5G2RBV3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9T4P2-1", "protein_name": "Uridine 5'-monophosphate synthase", "gene_name": "UMPS", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAADALLGSLVTGLYDVQAFKFGNFVLKSGLSSPVYIDLRGIISRPSILNQVAEMLFQTAENAEINFDTVCGVPYTALPLATIVCSTHEIPMLIRRKEKKDYGTKRLIEGAVNPGDTCLIIEDVVSSGSSVWETAEVLQKEGLKVTDAVVLVDREQGGRDNLQARGIRLHSVCTLSTVLRILEQQKKINAETVERVKRFIQENAFVAANPNDSLPSVKKEPKELSFGARAELPGTHPVAAKLLRLMQKKETNLCLSADVSESRELLQLADALGSRICLLKIHVDILNDFTLDVMKELTTLAKRHEFLIFEDRKFADIGNTVKKQYEGGVFKIASWADLVNAHAVPGSGVVKGLEEVGLPLHRACLLVAEMSSAGTLATGSYTEAAVQMAEEHSEFVIGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYHSPQEVIGKRGSDIIIVGRGIIASANQLEAAKMYRKAAWEAYLSRLAV", "length": 480 }, "evidence": [ { "id": "A0A5G2RBV3", "url": "https://omabrowser.org/oma/group/A0A5G2RBV3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0M2N2-1", "protein_name": "Uridine 5'-monophosphate synthase", "gene_name": "Umps", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVARQALGPLVTELYDVQAFKFGSFVLKSGLSSPVYIDLRGIVSRPRLLSQVADILFQTARNAGISFDSVCGVPYTALPLATVICSANHIPMLIRRKETKDYGTKRLVEGEINPGQTCLVIEDVVTSGASVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAQGIRLHSVCTLSEMLEILEQQKKIDAEMVGRVKRFIQENVFTAANHNGVPPPEKKACKELSFGARAELPGVHPLASKLLTLMQKKETNLCLSADVSEARELLQLADALGPSICMLKTHVDILNDFTLDVMEELTTLAKRHEFLIFEDRKFADIGNTVKKQYESGIFKIASWADVVNAHVVPGSGVVKGLQEVGLPLHRACLLIAEMSSAGSLATGDYTKAAVGMAEEHCEFVIGFISGSRVSMKPEFLHLTPGVQLETGGDHLGQQYNSPQEVVGKRGSDVIIVGRGILAAANRLEAAEMYRKAAWEAYLSFTAVNRHHDQGKSYKNSM", "length": 494 }, "evidence": [ { "id": "A0A5G2RBV3", "url": "https://omabrowser.org/oma/group/A0A5G2RBV3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B8JLL1-1", "protein_name": "Uridine 5'-monophosphate synthase", "gene_name": "umps", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDDTSLDSLILKLHDIQAVKFGTFKLKSGLSSPIYFDLRVIVSHPALMNQVADLLHKKSEEAGVQFDSVCGVPYTALPLATIICSSKQYPMLIRRKEAKDYGTKRLIEGTIRPGDRCLIVEDVVTSGSSVLETAEVLEKEGLKITDAVVLMDREQGGSTRLADSGITLHSVISISRLLEVLLKAGRIDTDTAQSVKRFVQDNNTYILKKNGSSAAKKSCGELSYGARAGLPDTHPLAARLMQIMEDKKTNLCVSADVTHSKELLDIAVTLGPLICVLKTHVDILEDFTADVASNLKELAKKHNFLIFEDRKFADIGNTVKHQYEGGLYRISSWAHIINAHALPGPGVLQGLGGVGNPLGHGCLLIAQMSSQGSLATGDYTQAVVKMAEDHSDFVFGFISGSKISEKPGMVHMTPGVQMQTGGDGLGQQYSSPEDVICTKGSDIIIVGRGILGSPDRLRAAGEYRTAGWEAYLKRLSLAS", "length": 479 }, "evidence": [ { "id": "A0A5G2RBV3", "url": "https://omabrowser.org/oma/group/A0A5G2RBV3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3GSP0-1", "protein_name": "Uridine 5'-monophosphate synthase", "gene_name": "Umps", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVASEALGLLVTELYDVQAFKFGSFVLKSGLTSPVYIDLRGIVSRPRLLSQVADILFQTAKNAEISFDSVCGVPYTALPLATVICSTNHIPMLIRRKETKDYGTKRLVEGEINPGQTCLIIEDVVTSGASVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAQGIRLHSVCTLSKMLEILEQQKKIDAEMVGRVKRFIQENVFIATNHNGVPPPEKKACKELSFGARAELPGVHPLASKLLRLMQKKETNLCLSADVSEARELLQLADALGPSICMLKTHVDILNDFTLDVMEELAALAKRHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRACLLIAEMSSAGSLATGNYTKAAVGMAEEHCGFVVGFISGSRVSMKPEFLHLTPGVQLETGGDHLGQQYNSPQEVIGKRGSDVIIVGRGILGASNRLEAAEMYRKAAWEAYLSRLAV", "length": 480 }, "evidence": [ { "id": "A0A5G2RBV3", "url": "https://omabrowser.org/oma/group/A0A5G2RBV3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P09556-1", "protein_name": "Uridine 5'-monophosphate synthase", "gene_name": "pyr56", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNIKELVLKLNEIDAIKLGEFKLKSGIISPIYIDLRVTVSSPPLLAAIAEMMYQKVYKSGNAQETPALVCGVPYTALPIATGMSIANNIPMVVRRKEAKAYGTKQLIEGRFKEGDNVLVVEDLVTSGASVLETVRDLNSVGLKVTDVVVLLDRQQGARQALEKQGYRLHSVFTMEELINTLIEAGKLTGRTLELVQSFLDANRNVVVPLPPTLAPPAPAPIVINKPFEERAKLASNPMASKLFTLMSSKKTNLAVAADLTDKQQLLDLAESIGSEICVLKTHVDIIDNYDEEFIKSLKCIAAKHNFLIFEDRKFADIGNTVKYQFENGVYKISKWADMVTVHGVAGSSIVDGFKSGLKEYGSGLLLLAQMSSKGSLCVGDYTTQMIEMANNNKEEVMGLICQERLPSMTDGLVLMTPGVQFNSTGDAMGQQYNTPEYIIKEKNTDVIIVGRGIYQSNDPKSVANKYRTAAWETYQSKF", "length": 478 }, "evidence": [ { "id": "A0A5G2RBV3", "url": "https://omabrowser.org/oma/group/A0A5G2RBV3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P11172-1", "protein_name": "Uridine 5'-monophosphate synthase", "gene_name": "UMPS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKMLEILEQQKKVDAETVGRVKRFIQENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLGV", "length": 480 }, "evidence": [ { "id": "A0A5G2RBV3", "url": "https://omabrowser.org/oma/group/A0A5G2RBV3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13439-1", "protein_name": "Uridine 5'-monophosphate synthase", "gene_name": "Umps", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVASQALGPLVTELYDVQAFKFGSFVLKSGLSSPVYIDLRGIVSRPRLLSQVADILFQTAKNAGISFDSVCGVPYTALPLATVICSANHIPMLIRRKETKDYGTKRLVEGEINPGQTCLVIEDVVTSGASVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAQGIRLHAVCTLSQMLEILQQQEKIDADMVGRVKRFIQENVFSAANHNGLPPPEKKACKELSFGARAELPGTHPLASKLLRLMQKKETNLCLSADVSEARELLQLADALGPSICMLKTHVDILNDFTLDVMEELTALAKRHEFLIFEDRKFADIGNTVKKQYESGTFKIASWADIVNAHVVPGSGVVKGLQEVGLPLHRACLLIAEMSSAGSLATGNYTKAAVGMAEEHCEFVIGFISGSRVSMKPEFLHLTPGVQLETGGDHLGQQYNSPQEVIGKRGSDVIIVGRGILAAANRLEAAEMYRKAAWEAYLSRLAVQ", "length": 481 }, "evidence": [ { "id": "A0A5G2RBV3", "url": "https://omabrowser.org/oma/group/A0A5G2RBV3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q01637-1", "protein_name": "Uridine 5'-monophosphate synthase", "gene_name": "r-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVAQNSDKMRALALKLFEINAFKFGDFKMKVGINSPVYFDLRVIVSYPDVMQTVSDLLVEHIKDKQLSAKHVCGVPYTALPLATIVSVQQGTPMLVRRKEAKAYGTKKLVEGIFNAGDTCLIVEDVVTSGSSILDTVRDLQGEGIVVTDAVVVVDREQGGVANIAKHGVRMHSLFTLSFLLNTLHEAGRIEKSTVEAVAKYIAAVQINSDGTFVGGDKGDVVRANDLQRTKLTYENRANLAKSAVAKRLFNLIASKQTNLCLAADLTHADEILDVADKCGPYICLLKTHVDIVEDFSDKFIADLQALAQRHNFLLMEDRKFADIGNTVSLQYGKGIYKISSWADLVTAHTLPGRSILQGLKAGLGEGGAGKERGVFLLAEMSASGNLIDAKYKENSNKIATEGADVDFVAGVVCQSSDAFAFPGLLQLTPGVKIDEGVDQLGQQYQSPEHVVKERGADIGVVGRGILKASSPKQAAQTYRDRLWAAYQDRVAK", "length": 493 }, "evidence": [ { "id": "A0A5G2RBV3", "url": "https://omabrowser.org/oma/group/A0A5G2RBV3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q42586-1", "protein_name": "Uridine 5'-monophosphate synthase", "gene_name": "PYRE-F", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSAMEALILQLHEIGAVKFGNFKLKSGIFSPVYIDLRLIVSYPSLLTQISQTLISSLPPSATFDVVCGVPYTALPIATVVSVSNGIPMLMRRKEIKDYGTSKAIEGIFEKDQTCLIIEDLVTSGASVLETAAPLRAVGLKVSDAVVLIDRQQGGRENLAENGIKLHSMIMLTDMVRVLKEKGKIEVEVEVNLLKFLEENRRVSVPSVEKPKPKPRVLGFKERSELSKNPTGKKLFDIMLKKETNLCLAADVGTAAELLDIADKVGPEICLLKTHVDILPDFTPDFGSKLRAIADKHKFLIFEDRKFADIGNTVTMQYEGGIFKILEWADIINAHVISGPGIVDGLKLKGMPRGRGLLLLAEMSSAGNLATGDYTAAAVKIADAHSDFVMGFISVNPASWKCGYVYPSMIHATPGVQMVKGGDALGQQYNTPHSVITERGSDIIIVGRGIIKAENPAETAHEYRVQGWNAYLEKCSQ", "length": 476 }, "evidence": [ { "id": "A0A5G2RBV3", "url": "https://omabrowser.org/oma/group/A0A5G2RBV3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "orotate phosphoribosyltransferase activity", "id": "GO:0004588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004588", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3" } ], "pmid": "" }, { "name": "orotidine-5'-phosphate decarboxylase activity", "id": "GO:0004590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004590", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "'de novo' pyrimidine nucleobase biosynthetic process", "id": "GO:0006207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006207", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3" } ], "pmid": "" }, { "name": "'de novo' UMP biosynthetic process", "id": "GO:0044205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044205", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3" } ], "pmid": "" }, { "name": "UDP biosynthetic process", "id": "GO:0006225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006225", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3" } ], "pmid": "" }, { "name": "UMP biosynthetic process", "id": "GO:0006222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006222", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3" } ], "pmid": "" }, { "name": "pyrimidine nucleobase biosynthetic process", "id": "GO:0019856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10380", "name": "", "equation": "orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10380", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10380" } ] }, { "id": "11596", "name": "", "equation": "orotidine 5'-phosphate + H(+) = UMP + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "11596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11596" } ] }, { "id": "R-SSC-73564", "name": "UMPS dimer decarboxylates OMP to UMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-111629" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-73564", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73564" } ] }, { "id": "R-SSC-73567", "name": "UMPS dimer transfers phosphoribosyl group to ORO to form OMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-76632" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-73567", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73567" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-111629", "participant_name": "OMP [cytosol]", "crossref": [ { "id": "57538", "database": "ChEBI", "url": "" }, { "id": "ZINC000004095542", "database": "ZINC", "url": "" }, { "id": "C01103", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-76632", "participant_name": "ORO [cytosol]", "crossref": [ { "id": "30839", "database": "ChEBI", "url": "" }, { "id": "ZINC000001408068", "database": "ZINC", "url": "" }, { "id": "C00295", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RBV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBV3" }, { "id": "SM00934", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00934" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Orotidine 5'-phosphate decarboxylase", "eco_id": "ECO_0000259", "start_pos": 253, "end_pos": 466, "start_aa": "Asn", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7F0-1", "uniprot_ac": "A0A5G2R7F0", "uniprot_id": "A0A5G2R7F0_PIG", "mass": { "chemical_mass": 25444.0, "monoisotopic_mass": 25444.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Glutathione S-transferase", "type": "recommended", "evidence": [ { "id": "A0A5G2R7F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.18", "type": "synonym", "evidence": [ { "id": "A0A5G2R7F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7F0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0", "locus": {} } ], "crossref": [ { "id": "A0A5G2R7F0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7F0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000037808", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037808", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00570", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00570", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03075", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03075", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03209", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03209", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571:SF137", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571:SF137", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00043", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00043", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156590", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "16437", "url": "https://www.rhea-db.org/rhea/16437", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZNH2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZNH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZP16", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZP16-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ADR1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ADR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q9Q5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q9Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7F0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBF9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLSEKFKLGLDFPNLPYLIDGAHKLTQSNAILRYIARKHNMCGETEEEKIRVDVLENQTRDTADDLASLCYSSDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDGFPNLRDFLSRFEGLKKIAAYMRSSRFLPGPLFLKVAMWGNK", "length": 218, "header": "tr|A0A5G2R7F0-1|A0A5G2R7F0_PIG Isoform 1 of Glutathione S-transferase OS=Sus scrofa OX=9823 GN= PE=1 SV=1 CANONICAL=A0A5G2R7F0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZNH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0/entry#A0A286ZNH2-1", "sequence": { "sequence": "MTLILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLSDKFNDLCLLFLQLPYLIDGAHKLTQSNAILRYIARKHNMCGETEEEKIRVDVLENQANDTSEALASLCYSPDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKAFLSRFELPYLIDGAHKLTQSNAILRYIACKHNMCGETEEEKIRMDILENQAMDVRLQMARICYSPDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKAFLSRFEGLERISAYMRSSRFLPHPVYSKMAMWGNK", "length": 349, "header": "tr|A0A286ZNH2-1|A0A5G2R7F0_PIG Computationally mapped isoform of Glutathione S-transferase OS=Sus scrofa OX=9823 GN= PE=1 SV=3 CANONICAL=A0A5G2R7F0-1" }, "locus": { "chromosome": "4", "start_pos": 110480894, "end_pos": 110451893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045665.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045665.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033003.3", "url": "https://www.ensembl.org/id/ENSSSCP00000033003.3" } ] } }, { "isoform_ac": "A0A286ZP16-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0/entry#A0A286ZP16-1", "sequence": { "sequence": "PPGSRHPMLLDYTDSNAPDYDRSQWLSDKFKLGLDFPNLPYLIDGAHKLTQSNAILRYIARGETEEEKIRVDVLENQVLDVCMQKVRICYSPDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKAFLSRFELPYLIDGAHKLTQSNAILRYIARKHNMCGETEEEKIRVDVLENQTRDTADDLASLCYSSDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKDFLSRFEGLERISAYMRSSRFLPHPVYTKMATWGNK", "length": 322, "header": "tr|A0A286ZP16-1|A0A5G2R7F0_PIG Computationally mapped isoform of Glutathione S-transferase OS=Sus scrofa OX=9823 GN= PE=1 SV=3 CANONICAL=A0A5G2R7F0-1" }, "locus": { "chromosome": "4", "start_pos": 110446118, "end_pos": 110428307, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047907.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047907.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033212.3", "url": "https://www.ensembl.org/id/ENSSSCP00000033212.3" } ] } }, { "isoform_ac": "A0A287ADR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0/entry#A0A287ADR1-1", "sequence": { "sequence": "MCGETEEEKIRVDVLENQVLDVCMQKVRICYSPDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKAFLSRFELAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLSEKFKLGLDFPNLPYLIDGAHKLTQSNAILRYIARKHNMCGETEEEKIRVDVLENQTRDTADDLASLCYSSDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKDFLSRFEGLERISAYMRSSRFLPHPVYTKMATWGNK", "length": 310, "header": "tr|A0A287ADR1-1|A0A5G2R7F0_PIG Computationally mapped isoform of Glutathione S-transferase OS=Sus scrofa OX=9823 GN= PE=1 SV=3 CANONICAL=A0A5G2R7F0-1" }, "locus": { "chromosome": "4", "start_pos": 110445275, "end_pos": 110428307, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040600.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040600.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041972.3", "url": "https://www.ensembl.org/id/ENSSSCP00000041972.3" } ] } }, { "isoform_ac": "A0A5G2Q9Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0/entry#A0A5G2Q9Q5-1", "sequence": { "sequence": "MTLILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLSEKFKLGLDFPNLPYLIDGAHKLTQSNAILRYIARKHNMCGETEEEKIRVDVLENQTRDTADDLASLCYSSDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKDFLSRFELTYLIDGAHKLTQSNAILRYIARKHNMCGETEEEKIRMARICYSPDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDGFPNLRDFLSRFEGLKKIAAYMRSSRFLPGPLFLKVAMWGNK", "length": 334, "header": "tr|A0A5G2Q9Q5-1|A0A5G2Q9Q5_PIG Computationally mapped isoform of Glutathione S-transferase OS=Sus scrofa OX=9823 GN= PE=1 SV=1 CANONICAL=A0A5G2R7F0-1" }, "locus": { "chromosome": "4", "start_pos": 110433588, "end_pos": 110416860, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070715.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070715.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060053.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060053.2" } ] } }, { "isoform_ac": "A0A5G2QWD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0/entry#A0A5G2QWD5-1", "sequence": { "sequence": "MTMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTLGDAPDYDRSQWLSDKFKLGLDFPNLPYLIDGAHKLTQSNAILRYIACKHNMCGETEEEKIRMDILENQAMDVRLQMARICYSPDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKAFLSRFELPYLIDGAHKLTQSNAILRYIARGETEEEKIRVDVLENQVLDVCMQKVRICYSPDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKAFLSRFEVSLLILVLFFISFLFPLLQNAFLVLELKLRTPAIC", "length": 349, "header": "tr|A0A5G2QWD5-1|A0A5G2R7F0_PIG Computationally mapped isoform of Glutathione S-transferase OS=Sus scrofa OX=9823 GN= PE=1 SV=1 CANONICAL=A0A5G2R7F0-1" }, "locus": { "chromosome": "4", "start_pos": 110457180, "end_pos": 110443807, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074128.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074128.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068465.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068465.2" } ] } }, { "isoform_ac": "A0A5G2QXZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0/entry#A0A5G2QXZ4-1", "sequence": { "sequence": "MTMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTLGDAPDYDRSQWLSDKFKLGLDFPNLPYLIDGAHKLTQSNAILRYIACKHNMCGETEEEKIRMDILENQAMDVRLQMARICYSPDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKAFLSRFEVTGSRHPMLLDYTDSNAPDYDRSQWLSDKFKLGLDFPNLPYLIDGAHKLTQSNAILRYIARGETEEEKIRVDVLENQVLDVCMQKVRICYSPDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKAFLSRFEVSLLILVLFFISFLFPLLQNAFLVLELKLRTPAIC", "length": 387, "header": "tr|A0A5G2QXZ4-1|A0A5G2R7F0_PIG Computationally mapped isoform of Glutathione S-transferase OS=Sus scrofa OX=9823 GN= PE=1 SV=2 CANONICAL=A0A5G2R7F0-1" }, "locus": { "chromosome": "4", "start_pos": 110457180, "end_pos": 110443807, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072521.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072521.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069791.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069791.2" } ] } }, { "isoform_ac": "A0A5G2R7F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0/entry#A0A5G2R7F0-1", "sequence": { "sequence": "MTLILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLSEKFKLGLDFPNLPYLIDGAHKLTQSNAILRYIARKHNMCGETEEEKIRVDVLENQTRDTADDLASLCYSSDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDGFPNLRDFLSRFEGLKKIAAYMRSSRFLPGPLFLKVAMWGNK", "length": 218, "header": "tr|A0A5G2R7F0-1|A0A5G2R7F0_PIG Isoform 1 of Glutathione S-transferase OS=Sus scrofa OX=9823 GN= PE=1 SV=1 CANONICAL=A0A5G2R7F0-1" }, "locus": { "chromosome": "4", "start_pos": 110433588, "end_pos": 110416860, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067633.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067633.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073172.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073172.1" } ] } }, { "isoform_ac": "A0A5G2RBF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0/entry#A0A5G2RBF9-1", "sequence": { "sequence": "MCGETEEEKIRVDVLENQANDTSEALASLCYSPDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKAFLSRFELAHAIRLLLEYTDSSYEEKKYTLGDAPDYDRSQWLSDKFKLGLDFPNLPYLIDGAHKLTQSNAILRYIACKHNMCGETEEEKIRMDILENQAMDVRLQMARICYSPDFEKLKPGYLKEIPEKMKPFSEFLGKRPWFAGDKLTYVDFLAYDVLDLYRIFDPKCLDEFPNLKAFLSRFEGLERISAYMRSSRFLPHPVYSKMAMWGNK", "length": 310, "header": "tr|A0A5G2RBF9-1|A0A5G2RBF9_PIG Computationally mapped isoform of glutathione transferase OS=Sus scrofa OX=9823 GN= PE=1 SV=1 CANONICAL=A0A5G2R7F0-1" }, "locus": { "chromosome": "4", "start_pos": 110479703, "end_pos": 110451893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081584.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081584.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073665.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073665.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZNH2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNH2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156590", "resource": "Reactome", "description": "Glutathione conjugation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7F0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7F0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7F0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7F0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0" } ], "pmid": "" }, { "name": "xenobiotic catabolic process", "id": "GO:0042178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042178", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7F0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7F0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16437", "name": "", "equation": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16437", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16437" } ] }, { "id": "R-SSC-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-176054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176054" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7F0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 218, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7F0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7F0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7A1-1", "uniprot_ac": "A0A5G2R7A1", "uniprot_id": "A0A5G2R7A1_PIG", "mass": { "chemical_mass": 63803.0, "monoisotopic_mass": 63803.0 }, "refseq": {}, "gene_names": [ { "name": "ME2", "type": "recommended", "evidence": [ { "id": "A0A5G2R7A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" } ] } ], "protein_names": [ { "name": "Malic enzyme", "type": "recommended", "evidence": [ { "id": "A0A5G2R7A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "NAD-dependent mitochondrial malic enzyme that catalyzes the oxidative decarboxylation of malate to pyruvate.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSJ2#function" }, { "database": "UniProtKB", "id": "ARBA00055709", "url": "https://www.uniprot.org/uniprotkb/ARBA00055709#function" }, { "database": "UniProtKB", "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1#function" }, { "database": "UniProtKB", "id": "A0A286ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS2#function" }, { "database": "UniProtKB", "id": "F1RPN9", "url": "https://www.uniprot.org/uniprotkb/F1RPN9#function" }, { "database": "UniProtKB", "id": "A0A5G2QB59", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB59#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ME2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1", "locus": { "chromosome": "1", "start_pos": 100476733, "end_pos": 100419760, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004522", "url": "https://www.ensembl.org/id/ENSSSCG00000004522" } ] } } ], "crossref": [ { "id": "A0A5G2R7A1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7A1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004522", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004522", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05312", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05312", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23406", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23406", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23406:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23406:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03949", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03949", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-70268", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70268", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "12653", "url": "https://www.rhea-db.org/rhea/12653", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "15641", "url": "https://www.rhea-db.org/rhea/15641", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZNS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXT4", "url": "https://www.uniprot.org/uniprotkb/A0A287AXT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QB59", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QB59-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPN9", "url": "https://www.uniprot.org/uniprotkb/F1RPN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPN9-1", "url": "https://www.uniprot.org/uniprotkb/F1RPN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLSRFKIVATPCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNVKKLNGPLEKYIYIMGIQERNEKLFYRILQDDIETLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNPALLKDPFYMGLYQKRDRSQRYDDLIDEFMKAITDRYGRNILIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVIGKSISEHKILFLGAGEAALGIANLIVMAMVENGLSEEEAQKKIWMVDKFGLLFKGRKAKIDSHQEPFAHPAPDNIPDNFEDAVNILKPSAIIGVAGAGRLFTHNVIKAMADINERPIIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLSDGQVFTPGQGNNVYIFPGVALAVILCNTRHISDHVFLEAAKALTSQLTDKELAQGRLYPPLANIQEVSINIAIKVSNQAAPMAYGGSQTRGRIGAAPAGLHHSHSNDRSLTHSARPGIKPAT", "length": 578, "header": "tr|A0A5G2R7A1-1|A0A5G2R7A1_PIG Isoform 1 of Malic enzyme OS=Sus scrofa OX=9823 GN=ME2 PE=1 SV=2 CANONICAL=A0A5G2R7A1-1" }, "isoforms": [ { "isoform_ac": "A0A286ZNS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1/entry#A0A286ZNS2-1", "sequence": { "sequence": "MGAGAGLLSPGQGSRLRTRCRLPRVRPSRSPLRGWEGGVNGRERKRLTESRLRTGAAGRMAATLSSAVGGSSLALRDATSQSRAPSFRLVVREMMLSRFKIVATPCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNVKKLNGPLEKYIYIMGIQERNEKLFYRILQDDIETLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNPALLKDPFYMGLYQKRDRSQRYDDLIDEFMKAITDRYGRNILIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVIGKSISEHKILFLGAGEAALGIANLIVMAMVENGLSEEEAQKKIWMVDKFGLLFKGRKAKIDSHQEPFAHPAPDNIPDNFEDAVNILKPSAIIGVAGAGRLFTHNVIKAMADINERPIIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLSDGQVFTPGQGNNVYIFPGVALAVILCNTRHISDHVFLEAAKALTSQLTDKELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKARYIRERIWRSEYDSLLPDVYEWPESASHPPQITE", "length": 678, "header": "tr|A0A286ZNS2-1|A0A5G2R7A1_PIG Computationally mapped isoform of Malic enzyme OS=Sus scrofa OX=9823 GN=ME2 PE=1 SV=1 CANONICAL=A0A5G2R7A1-1" }, "locus": { "chromosome": "1", "start_pos": 100475089, "end_pos": 100420019, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054033.2", "url": "https://www.ensembl.org/id/ENSSSCT00000054033.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033232.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033232.2" } ] } }, { "isoform_ac": "A0A287AXT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1/entry#A0A287AXT4-1", "sequence": { "sequence": "MMLSRFKIVATPCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNVKKLNGPLEKYIYIMGIQERNEKLFYRILQDDIETLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKALLKDPFYMGLYQKRDRSQRYDDLIDEFMKAITDRYGRNILIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVIGKSISEHKILFLGAGEAALGIANLIVMAMVENGLSEEEAQKKIWMVDKFGLLFKGRKAKIDSHQEPFAHPAPDNIPDNFEDAVNILKPSAIIGVAGAGRLFTHNVIKAMADINERPIIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLSDGQVFTPGQGNNVYIFPGVALAVILCNTRHISDHVFLEAAKALTSQLTDKELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKARYIRERIWRSEYDSLLPDVYEWPESASHPPQITE", "length": 531, "header": "tr|A0A287AXT4-1|A0A5G2R7A1_PIG Computationally mapped isoform of Malic enzyme OS=Sus scrofa OX=9823 GN=ME2 PE=1 SV=3 CANONICAL=A0A5G2R7A1-1" }, "locus": { "chromosome": "1", "start_pos": 100475089, "end_pos": 100427201, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062663.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062663.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048761.3", "url": "https://www.ensembl.org/id/ENSSSCP00000048761.3" } ] } }, { "isoform_ac": "A0A5G2QB59-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1/entry#A0A5G2QB59-1", "sequence": { "sequence": "MMLSRFKIVATPCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNVKKLNGPLEKYIYIMGIQERNEKLFYRILQDDIETLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNPALLKDPFYMGLYQKRDRSQRYDDLIDEFMKAITDRYGRNILIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVIGKSISEHKILFLGAGEAALGIANLIVMAMVENGLSEEEAQKKIWMVDKFGLLFKGRKAKIDSHQEPFAHPAPDNIPDNFEDAVNILKPSAIIGVAGAGRLFTHNVIKAMADINERPIIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLSDGQVFTPGQGNNVYIFPGVALAVILCNTRHISDHVFLEAAKALTSQLTDKELAQGRLYPPLANIQEVSINIAIKAPVAYGDSQARGLIRAVAAGLCQSHSNEGSKRVCDPHHSSQQRRILNPLSKTRDQTCNLMGS", "length": 592, "header": "tr|A0A5G2QB59-1|A0A5G2QB59_PIG Computationally mapped isoform of Malic enzyme OS=Sus scrofa OX=9823 GN=ME2 PE=1 SV=1 CANONICAL=A0A5G2R7A1-1" }, "locus": { "chromosome": "1", "start_pos": 100472405, "end_pos": 100427201, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070940.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070940.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061284.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061284.1" } ] } }, { "isoform_ac": "A0A5G2QSJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1/entry#A0A5G2QSJ2-1", "sequence": { "sequence": "MMLSRFKIVATPCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNVKKLNGPLEKYIYIMGIQERNEKLFYRILQDDIETLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNPALLKDPFYMGLYQKRDRSQRYDDLIDEFMKAITDRYGRNILIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVIGKSISEHKILFLGAGEAALGIANLIVMAMVENGLSEEEAQKKIWMVDKFGLLFKGRKAKIDSHQEPFAHPAPDNIPDNFEDAVNILKPSAIIGVAGAGRLFTHNVIKAMADINERPIIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLSDGQVFTPGQGNNVYIFPGYRIPIC", "length": 480, "header": "tr|A0A5G2QSJ2-1|A0A5G2R7A1_PIG Computationally mapped isoform of Malic enzyme OS=Sus scrofa OX=9823 GN=ME2 PE=1 SV=2 CANONICAL=A0A5G2R7A1-1" }, "locus": { "chromosome": "1", "start_pos": 100474944, "end_pos": 100427201, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073809.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073809.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067900.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067900.2" } ] } }, { "isoform_ac": "A0A5G2R7A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1/entry#A0A5G2R7A1-1", "sequence": { "sequence": "MMLSRFKIVATPCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNVKKLNGPLEKYIYIMGIQERNEKLFYRILQDDIETLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNPALLKDPFYMGLYQKRDRSQRYDDLIDEFMKAITDRYGRNILIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVIGKSISEHKILFLGAGEAALGIANLIVMAMVENGLSEEEAQKKIWMVDKFGLLFKGRKAKIDSHQEPFAHPAPDNIPDNFEDAVNILKPSAIIGVAGAGRLFTHNVIKAMADINERPIIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLSDGQVFTPGQGNNVYIFPGVALAVILCNTRHISDHVFLEAAKALTSQLTDKELAQGRLYPPLANIQEVSINIAIKVSNQAAPMAYGGSQTRGRIGAAPAGLHHSHSNDRSLTHSARPGIKPAT", "length": 578, "header": "tr|A0A5G2R7A1-1|A0A5G2R7A1_PIG Isoform 1 of Malic enzyme OS=Sus scrofa OX=9823 GN=ME2 PE=1 SV=2 CANONICAL=A0A5G2R7A1-1" }, "locus": { "chromosome": "1", "start_pos": 100471141, "end_pos": 100427201, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089248.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089248.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070007.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070007.2" } ] } }, { "isoform_ac": "F1RPN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1/entry#F1RPN9-1", "sequence": { "sequence": "MMLSRFKIVATPCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNVKKLNGPLEKYIYIMGIQERNEKLFYRILQDDIETLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNPALLKDPFYMGLYQKRDRSQRYDDLIDEFMKAITDRYGRNILIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVIGKSISEHKILFLGAGEGRKAKIDSHQEPFAHPAPDNIPDNFEDAVNILKPSAIIGVAGAGRLFTHNVIKAMADINERPIIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLSDGQVFTPGQGNNVYIFPGVALAVILCNTRHISDHVFLEAAKALTSQLTDKELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKARYIRERIWRSEYDSLLPDVYEWPESASHPPQITE", "length": 547, "header": "tr|F1RPN9-1|A0A5G2R7A1_PIG Computationally mapped isoform of Malic enzyme OS=Sus scrofa OX=9823 GN=ME2 PE=1 SV=5 CANONICAL=A0A5G2R7A1-1" }, "locus": { "chromosome": "1", "start_pos": 100475089, "end_pos": 100427201, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004994.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004994.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004876.5", "url": "https://www.ensembl.org/id/ENSSSCP00000004876.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZNS2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-70268", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70268", "resource": "Reactome", "description": "Pyruvate metabolism" }, { "id": "R-SSC-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" } ], "pmid": "" }, { "name": "malate dehydrogenase (decarboxylating) (NAD+) activity", "id": "GO:0004471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" } ], "pmid": "" }, { "name": "malate dehydrogenase (decarboxylating) (NADP+) activity", "id": "GO:0004473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004473", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" } ], "pmid": "" }, { "name": "malic enzyme activity", "id": "GO:0004470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004470", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "malate metabolic process", "id": "GO:0006108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006108", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" } ], "pmid": "" }, { "name": "regulation of NADP metabolic process", "id": "GO:1902031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902031", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12653", "name": "", "equation": "(S)-malate + NAD(+) = pyruvate + CO2 + NADH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12653", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12653" } ] }, { "id": "15641", "name": "", "equation": "oxaloacetate + H(+) = pyruvate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "15641", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15641" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7A1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 578, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7A1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7A1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" }, { "id": "SM01274", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01274" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Malic enzyme N-terminal", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 271, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R7A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" }, { "id": "SM00919", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00919" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Malic enzyme NAD-binding", "eco_id": "ECO_0000259", "start_pos": 281, "end_pos": 536, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A287AXT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287AXT4#function" }, { "id": "A0A287AXT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287AXT4" }, { "id": "PIRSR000106-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000106-3" } ], "binding_site_uniprot": 202, "amino_acid": "Val", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 202, "end_pos": 202, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287AXT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287AXT4#function" }, { "id": "A0A287AXT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287AXT4" }, { "id": "PIRSR000106-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000106-3" } ], "binding_site_uniprot": 203, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 203, "end_pos": 203, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287AXT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287AXT4#function" }, { "id": "A0A287AXT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287AXT4" }, { "id": "PIRSR000106-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000106-3" } ], "binding_site_uniprot": 226, "amino_acid": "Arg", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 226, "end_pos": 226, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QB59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB59#function" }, { "id": "A0A5G2QB59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB59" }, { "id": "PIRSR000106-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000106-3" }, { "id": "A0A5G2QSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSJ2#function" }, { "id": "A0A5G2QSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSJ2" }, { "id": "A0A5G2R7A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1#function" }, { "id": "A0A5G2R7A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" }, { "id": "F1RPN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPN9#function" }, { "id": "F1RPN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPN9" } ], "binding_site_uniprot": 256, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 256, "end_pos": 256, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QB59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB59#function" }, { "id": "A0A5G2QB59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB59" }, { "id": "PIRSR000106-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000106-3" }, { "id": "A0A5G2QSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSJ2#function" }, { "id": "A0A5G2QSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSJ2" }, { "id": "A0A5G2R7A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1#function" }, { "id": "A0A5G2R7A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" }, { "id": "F1RPN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPN9#function" }, { "id": "F1RPN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPN9" } ], "binding_site_uniprot": 257, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 257, "end_pos": 257, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QB59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB59#function" }, { "id": "A0A5G2QB59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB59" }, { "id": "PIRSR000106-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000106-3" }, { "id": "A0A5G2QSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSJ2#function" }, { "id": "A0A5G2QSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSJ2" }, { "id": "A0A5G2R7A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1#function" }, { "id": "A0A5G2R7A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A1" }, { "id": "F1RPN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPN9#function" }, { "id": "F1RPN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPN9" } ], "binding_site_uniprot": 280, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 280, "end_pos": 280, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A286ZNS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS2#function" }, { "id": "A0A286ZNS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS2" }, { "id": "PIRSR000106-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000106-3" } ], "binding_site_uniprot": 349, "amino_acid": "Gly", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 349, "end_pos": 349, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A286ZNS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS2#function" }, { "id": "A0A286ZNS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS2" }, { "id": "PIRSR000106-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000106-3" } ], "binding_site_uniprot": 350, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 350, "end_pos": 350, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A286ZNS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS2#function" }, { "id": "A0A286ZNS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS2" }, { "id": "PIRSR000106-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000106-3" } ], "binding_site_uniprot": 373, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 373, "end_pos": 373, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R6C9-1", "uniprot_ac": "A0A5G2R6C9", "uniprot_id": "A0A5G2R6C9_PIG", "mass": { "chemical_mass": 35541.0, "monoisotopic_mass": 35541.0 }, "refseq": { "ac": "XP_020946879", "name": "ribosome production factor 2 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946879" }, "gene_names": [ { "name": "RPF2", "type": "recommended", "evidence": [ { "id": "A0A5G2R6C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9" } ] }, { "name": "RPF2", "type": "synonym", "evidence": [ { "id": "XP_020946879", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946879" } ] } ], "protein_names": [ { "name": "Ribosome production factor 2 homolog", "type": "recommended", "evidence": [ { "id": "A0A5G2R6C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9/entry#names_and_taxonomy" } ] }, { "name": "Ribosome biogenesis protein RPF2 homolog", "type": "synonym", "evidence": [ { "id": "A0A5G2R6C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9/entry#names_and_taxonomy" } ] }, { "name": "ribosome production factor 2 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020946879", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946879" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPF2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9", "locus": { "chromosome": "1", "start_pos": 76963831, "end_pos": 76917185, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004394", "url": "https://www.ensembl.org/id/ENSSSCG00000004394" } ] } } ], "crossref": [ { "id": "A0A5G2R6C9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6C9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004394", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004394", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100525264", "url": "https://www.ncbi.nlm.nih.gov/gene/100525264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525264", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525264", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VGLKPMF", "url": "https://omabrowser.org/oma/group/VGLKPMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R6C9", "url": "https://www.orthodb.org/?gene=A0A5G2R6C9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12728", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12728", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12728:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12728:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04427", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04427", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020946879", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946879", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZNS9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZNS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6C9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT06", "url": "https://www.uniprot.org/uniprotkb/F1RT06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT06-1", "url": "https://www.uniprot.org/uniprotkb/F1RT06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDALDRVVKPQTKRAKRFLEKREPKLSENIKNAMLIKGGNANSTVTQVLRDVYALKKPYGVLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGVEKFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVPNIRLAGLDYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDQEKKAKRIKKN", "length": 306, "header": "tr|A0A5G2R6C9-1|A0A5G2R6C9_PIG Isoform 1 of Ribosome production factor 2 homolog OS=Sus scrofa OX=9823 GN=RPF2 PE=1 SV=1 CANONICAL=A0A5G2R6C9-1" }, "isoforms": [ { "isoform_ac": "A0A286ZNS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9/entry#A0A286ZNS9-1", "sequence": { "sequence": "MDALDRVVKPQTKRAKRFLEKREPKLSENIKNAMLIKGGNANSTVTQVLRDVVCMKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGVEKFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVPNIRLAGLDYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDQEKKAKRIKKN", "length": 296, "header": "tr|A0A286ZNS9-1|A0A5G2R6C9_PIG Computationally mapped isoform of Ribosome production factor 2 homolog OS=Sus scrofa OX=9823 GN=RPF2 PE=1 SV=2 CANONICAL=A0A5G2R6C9-1" }, "locus": { "chromosome": "1", "start_pos": 76958121, "end_pos": 76917274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043824.2", "url": "https://www.ensembl.org/id/ENSSSCT00000043824.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033127.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033127.2" } ] } }, { "isoform_ac": "A0A5G2R6C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9/entry#A0A5G2R6C9-1", "sequence": { "sequence": "MDALDRVVKPQTKRAKRFLEKREPKLSENIKNAMLIKGGNANSTVTQVLRDVYALKKPYGVLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGVEKFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVPNIRLAGLDYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDQEKKAKRIKKN", "length": 306, "header": "tr|A0A5G2R6C9-1|A0A5G2R6C9_PIG Isoform 1 of Ribosome production factor 2 homolog OS=Sus scrofa OX=9823 GN=RPF2 PE=1 SV=1 CANONICAL=A0A5G2R6C9-1" }, "locus": { "chromosome": "1", "start_pos": 76958121, "end_pos": 76917274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105440.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105440.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078635.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078635.1" } ] } }, { "isoform_ac": "F1RT06-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9/entry#F1RT06-1", "sequence": { "sequence": "MDALDRVVKPQTKRAKRFLEKREPKLSENIKNAMLIKGGNANSTVTQVLRDVEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGVEKFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVPNIRLAGLDYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDQEKKAKRIKKN", "length": 280, "header": "tr|F1RT06-1|A0A5G2R6C9_PIG Computationally mapped isoform of Ribosome production factor 2 homolog OS=Sus scrofa OX=9823 GN=RPF2 PE=1 SV=3 CANONICAL=A0A5G2R6C9-1" }, "locus": { "chromosome": "1", "start_pos": 76958121, "end_pos": 76917274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004857.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004857.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004743.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004743.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZNS9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNS9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525264", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525264", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PVA3-1", "protein_name": "Ribosome production factor 2 homolog", "gene_name": "RPF2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDALDRVVKPKTKRAKRFLEKREPKLTENTKNAMLIKGGNANSTVTEVLKDIYALKKPFAVMYKKKNITRPFEDQTSLEFFSKKSDCSLFLFGSHNKKRPNNLIVGRMFDYHVLDMIELGIENFVSLKDIKNNKCPEGTKPMLIFAGDTFDLSEEYRRLKSLLIDFFRGPTVPNIRLAGLEHVLHFTAVDGKIYMRSYKVLLKKSGCKIPRIELEDIGPSLDLVMRRTHLASDDLYKLSLKQPKALKPKKKKNISHDVFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAEKSAEDGGISPKKTKSV", "length": 306 }, "evidence": [ { "id": "A0A5G2R6C9", "url": "https://omabrowser.org/oma/group/A0A5G2R6C9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F7ENM1-1", "protein_name": "Ribosome production factor 2 homolog", "gene_name": "Rpf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDALDKVLKPKTKRAKRFLEKREPKLSENIKNAMLIKGGNANATVTQVLRDVYALKKPYGVLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIEKFVSLKDIKTSKCPEGTKPMLIFAGDDFDVTEDYRRLKNLLIDFFRGPTVSNVRLAGLEYVLHFTALNGKVYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVVRRTHLASDDLYKLSMKVPKALKPKKRKNISQDTFGTTFGRIHMQKQDLSKLQTRKVKGLKKRPAENGVEDQGKKSKRIKKS", "length": 306 }, "evidence": [ { "id": "A0A5G2R6C9", "url": "https://omabrowser.org/oma/group/A0A5G2R6C9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36160-1", "protein_name": "Ribosome biogenesis protein RPF2", "gene_name": "RPF2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MIRTVKPKNARAKRALVKREAKLVENVKQALFIPGQSCNKNLHDIMVDLSALKKPDMKRFNRKNDIHPFEDMSPLEFFSEKNDCSLMVLMTSSKKRKNNMTFIRTFGYKIYDMIELMVADNFKLLSDFKKLTFTVGLKPMFTFQGAAFDTHPVYKQIKSLFLDFFRGESTDLQDVAGLQHVISMTIQGDFQDGEPLPNVLFRVYKLKSYKSDQGGKRLPRIELVEIGPRLDFKIGRIHTPSPDMVTEAHKKPKQLEMKTKKNVELDIMGDKLGRIHMGKQDLGKLQTRKMKGLKSKFDQGTEEGDGEVDEDYEDEASYSDDGQEYEEEFVSATDIEPSAKRQKK", "length": 344 }, "evidence": [ { "id": "A0A5G2R6C9", "url": "https://omabrowser.org/oma/group/A0A5G2R6C9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54DJ0-1", "protein_name": "Ribosome production factor 2 homolog", "gene_name": "bxdc1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSKPKKIFLKREPSKSHAAKKFLRNKEAKEVEIVKQAMFIRGQQSSDIIQKLQKDLFMLKKPEAIQYNKKNAFRPMESAESIEFLGEKSNSSLFTFGSHSKKREHNLIMGRLFDNAVFDMIEMGISNFKSIKEFGADGSAVGNKPMFIFQGNEFENNETVKKVGNLFLDMFRGRLVEYINLVGLDHVVIMTAVDDKILFRHYTTIFSPSGSKIPKVDLKEVGPSFDITIRRTKLASADLEKEAYKVHKSVVPKAKKNVETDALGQTFGTVYKNHQDFNKIAFRKNRALRGKNPVPTLNQAATSVDV", "length": 307 }, "evidence": [ { "id": "A0A5G2R6C9", "url": "https://omabrowser.org/oma/group/A0A5G2R6C9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9H7B2-1", "protein_name": "Ribosome production factor 2 homolog", "gene_name": "RPF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTLDRVVKPKTKRAKRFLEKREPKLNENIKNAMLIKGGNANATVTKVLKDVYALKKPYGVLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIENFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLAGLEYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDHEKKSKRIKKN", "length": 306 }, "evidence": [ { "id": "A0A5G2R6C9", "url": "https://omabrowser.org/oma/group/A0A5G2R6C9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJ80-1", "protein_name": "Ribosome production factor 2 homolog", "gene_name": "Rpf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDALDKVLKPKTKRAKRFLEKREPKLTENIKNAMLIKGGNANATVTQVLRDMYALKKPYGVLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIEKFVSLKDIKTSKCPEGTKPMLIFAGDDFDVTEDFRRLKNLLIDFFRGPTVSNVRLAGLEYVLHFTALNGKVYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVMRRTHLASDDLYKLSMKVPKALKPKKRKNISQDTFGTTFGRIHMQKQDLSKLQTRKMKGLKKRPAENGVDDQGKKSKRIKKN", "length": 306 }, "evidence": [ { "id": "A0A5G2R6C9", "url": "https://omabrowser.org/oma/group/A0A5G2R6C9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LUG5-1", "protein_name": "Ribosome production factor 2 homolog", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMEIRTPKTGKAKRVLESRAPKLVETGKKTLILHGTKTSATLSSVMTELYRLKKGGAIRYSRRNENIRPFESGGETSLEFFSQKTDCSIFVYGSHTKKRPDNLVLGRMYDHQVYDLIEVGIENFKSLRAFSYDKKFAPHEGTKPFICFIGEGFENVSELKHLKEVLTDLFRGEVVDNLNLTGLDRAYVCSAISPTKVFLTHCALKLKKSGSIVPRMELVEVGPSMDLVIRRNRLPNDSLMKEAMRTSKDKPKKKEKNVDQDAVLGKTGKIYMPDQKLKEMKLFDKSKGSKRERKDAKLKHKEETVAKKMKVSSE", "length": 314 }, "evidence": [ { "id": "A0A5G2R6C9", "url": "https://omabrowser.org/oma/group/A0A5G2R6C9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VEB3-1", "protein_name": "Ribosome production factor 2 homolog", "gene_name": "Non3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLLRIRKPKTRKGKKVLLAREPQLIESARTMLFLDGRKCGGNVKLCMKDLQALKKPLVKVLNRKNDITPFDDPSSLEFLTMKNDAALFTFGSTSKKRPDNIILGRIFENEVLDMFELGIKRYQAISEFKNEKIGACVKPCLVFNGPKWAQTEELRRLRNLFIDTFQREKVDSIRLQGIEHVLSFTVTDDMNILMRSYRILLKKSGQRTPRIELEEIGPSADFSIRRTKIASEDLYKQARKQPKQLKVGKKKNISTDALGNTKGRVHLGKQQTGSIQTRRVKALRKTPEEKKENRQRKKVALKAAAAEALASQGNNPFSS", "length": 320 }, "evidence": [ { "id": "A0A5G2R6C9", "url": "https://omabrowser.org/oma/group/A0A5G2R6C9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9" } ], "pmid": "" }, { "name": "5S rRNA binding", "id": "GO:0008097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008097", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA", "id": "GO:0000470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000470", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9" } ], "pmid": "" }, { "name": "protein localization to nucleolus", "id": "GO:1902570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902570", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9" } ], "pmid": "" }, { "name": "regulation of signal transduction by p53 class mediator", "id": "GO:1901796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901796", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R6C9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 306, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R6C9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6C9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R6C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C9" }, { "id": "PS50833", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50833" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Brix", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 234, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 253, "end_pos": 255 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9Z1-1", "uniprot_ac": "A0A5G2R9Z1", "uniprot_id": "A0A5G2R9Z1_PIG", "mass": { "chemical_mass": 88988.0, "monoisotopic_mass": 88988.0 }, "refseq": { "ac": "XP_020927210", "name": "CCR4-NOT transcription complex subunit 10 isoform X8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020927210" }, "gene_names": [ { "name": "CNOT10", "type": "recommended", "evidence": [ { "id": "A0A5G2R9Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1" } ] }, { "name": "CNOT10", "type": "synonym", "evidence": [ { "id": "XP_020927210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020927210" } ] } ], "protein_names": [ { "name": "CCR4-NOT transcription complex subunit 10", "type": "recommended", "evidence": [ { "id": "A0A5G2R9Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1/entry#names_and_taxonomy" } ] }, { "name": "CCR4-NOT transcription complex subunit 10 isoform X8", "type": "synonym", "evidence": [ { "id": "XP_020927210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020927210" } ] } ], "function": [ { "annotation": "Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZR44", "url": "https://www.uniprot.org/uniprotkb/A0A286ZR44#function" }, { "database": "UniProtKB", "id": "RU367083", "url": "https://www.uniprot.org/uniprotkb/RU367083#function" }, { "database": "UniProtKB", "id": "A0A286ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUN1#function" }, { "database": "UniProtKB", "id": "A0A8W4FEG4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEG4#function" }, { "database": "UniProtKB", "id": "A0A287A7Y4", "url": "https://www.uniprot.org/uniprotkb/A0A287A7Y4#function" }, { "database": "UniProtKB", "id": "A0A5G2QS40", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS40#function" }, { "database": "UniProtKB", "id": "A0A4X1U9C7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9C7#function" }, { "database": "UniProtKB", "id": "A0A5G2Q7Q8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q7Q8#function" }, { "database": "UniProtKB", "id": "A0A4X1UBN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBN9#function" }, { "database": "UniProtKB", "id": "A0A5G2R9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CNOT10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1", "locus": { "chromosome": "13", "start_pos": 18736068, "end_pos": 18649746, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000032220", "url": "https://www.ensembl.org/id/ENSSSCG00000032220" } ] } } ], "crossref": [ { "id": "A0A5G2R9Z1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9Z1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000032220", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000032220", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100623377", "url": "https://www.ncbi.nlm.nih.gov/gene/100623377", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039740", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039740", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R9Z1", "url": "https://www.orthodb.org/?gene=A0A5G2R9Z1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12979", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12979", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12979:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12979:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27626", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27626", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-429947", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6804115", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804115", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020927210", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020927210", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZR44", "url": "https://www.uniprot.org/uniprotkb/A0A286ZR44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZR44-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZR44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZUN1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZUN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A7Y4", "url": "https://www.uniprot.org/uniprotkb/A0A287A7Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A7Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A7Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U9C7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U9C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9C7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UBN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UBN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q7Q8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q7Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q7Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q7Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS40", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS40-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEG4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSVGLKSVKVCASKSSVRLESQPCSLGQSRRKVKLTDNRSYTLSIGNGDYFWTSKDTLWNYVQTLSDQGAEKHEGPGQSSGITDQEKELSTNAFQAFTAGNYDVCLQHLACLQDINKDDYKIILNTAVAEFFKSNQTTTDSLRQTLNQLKNQVHSAVEEMDGLDDVENSMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQAVCFLLVDLYILTYQAEKALHLLAVLEKMISQGNNNKNGKNEAGNNTNKDTSNHKGESGALIEAAKSKIHQYKVRAYIQMKSLKACKREIKSVMNTAGNSAPSLFLKSNFEYLRGNYRKAVKLLNSSNIAEHPGFMKTGECLRCMFWNNLGCIHFAMSKHNLGIFYFKKALQENDNVCAQLSAGSTDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFECLIEAVQVYHANPRLWLRLAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSIQNTVYNDGQSSAIPVASMEFAAICLRNALLLLPEEQQDPKQENGSKNSNQLGGNAESSESSDTCSSKSHDGDKFIPAPPSSPLRKQELENLKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTLSEMRKKPVFQPVHPIQPIQMPAFTVQRK", "length": 803, "header": "tr|A0A5G2R9Z1-1|A0A5G2R9Z1_PIG Isoform 1 of CCR4-NOT transcription complex subunit 10 OS=Sus scrofa OX=9823 GN=CNOT10 PE=1 SV=1 CANONICAL=A0A5G2R9Z1-1" }, "isoforms": [ { "isoform_ac": "A0A286ZR44-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1/entry#A0A286ZR44-1", "sequence": { "sequence": "MAADKPSDQGAEKHEGPGQSSGITDQEKELSTNAFQAFTAGNYDVCLQHLACLQDINKDDYKIILNTAVAEFFKSNQTTTDSLRQTLNQLKNQVHSAVEEMDGLDDVENSMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQAVCFLLVDLYILTYQAEKALHLLAVLEKMISQGNNNKNGKNEAGNNTNKDTSNHKGESGALIEAAKSKIHQYKVRAYIQMKSLKACKREIKSVMNTAGNSAPSLFLKSNFEYLRGNYRKAVKLLNSSNIAEHPGFMKTGECLRCMFWNNLGCIHFAMSKHNLGIFYFKKALQENDNVCAQLSAGSTDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFECLIEAVQVYHANPRLWLRLAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSIQNTVYNDGQSSAIPVASMEFAAICLRNALLLLPEEQQDPKQENGSKNSNQLGGNAESSESSDTCSSKSHDGDKFIPAPPSSPLRKQELENLKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGIHMILIENLIQNAVALNGNTQLALQIIKRNQLLPAVKTLSEMRKKPVFQPVHPIQPIQMPAFTVQRK", "length": 761, "header": "tr|A0A286ZR44-1|A0A5G2R9Z1_PIG Computationally mapped isoform of CCR4-NOT transcription complex subunit 10 OS=Sus scrofa OX=9823 GN=CNOT10 PE=1 SV=2 CANONICAL=A0A5G2R9Z1-1" }, "locus": { "chromosome": "13", "start_pos": 18730838, "end_pos": 18649987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045420.2", "url": "https://www.ensembl.org/id/ENSSSCT00000045420.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034090.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034090.2" } ] } }, { "isoform_ac": "A0A286ZUN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1/entry#A0A286ZUN1-1", "sequence": { "sequence": "MAADKPSDQGAEKHEGPGQSSGITDQEKELSTNAFQAFTAGNYDVCLQHLACLQDINKDDYKIILNTAVAEFFKSNQTTTDSLRQTLNQLKNQVHSAVEEMDGLDDVENSMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQAVCFLLVDLYILTYQAEKALHLLAVLEKMISQGNNNKNGKNEAGNNTNKDTSNHKGESGALIEAAKSKIHQYKVRAYIQMKSLKACKREIKSVMNTAGNSAPSLFLKSNFEYLRGNYRKAVKLLNSSNIAEHPGFMKTGECLRCMFWNNLGCIHFAMSKHNLGIFYFKKALQENDNVCAQLSAGSTDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFECLIEAVQVYHANPRLWLRLAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSIQNTVYNDGQSSAIPVASMEFAAICLRNALLLLPEEQQDPKQENGSKNSNQLGGNAESSESKALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTLSEMRKKPVFQPVHPIQPIQMPAFTVQRK", "length": 665, "header": "tr|A0A286ZUN1-1|A0A5G2R9Z1_PIG Computationally mapped isoform of CCR4-NOT transcription complex subunit 10 OS=Sus scrofa OX=9823 GN=CNOT10 PE=1 SV=2 CANONICAL=A0A5G2R9Z1-1" }, "locus": { "chromosome": "13", "start_pos": 18730838, "end_pos": 18649987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038047.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038047.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035196.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035196.2" } ] } }, { "isoform_ac": "A0A287A7Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1/entry#A0A287A7Y4-1", "sequence": { "sequence": "MAADKPSDQGAEKHEGPGQSSGITDQEKELSTNAFQAFTAGNYDVCLQHLACLQDINKDDYKIILNTAVAEFFKSNQTTTDSLRQTLNQLKNQVHSAVEEMDGLDDVENSMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQAVCFLLVDLYILTYQAEKALHLLAVLEKMISQGNNNKNGKNEAGNNTNKDTSNHKGESGALIEAAKSKIHQYKVRAYIQMKSLKACKREIKSVMNTAGNSAPSLFLKSNFEYLRGNYRKAVKLLNSSNIAEHPGFMKTGECLRCMFWNNLGCIHFAMSKHNLGIFYFKKALQENDNVCAQLSAGSTDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFECLIEAVQVYHANPRLWLRLAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSIQNTVYNDGQSSAIPVASMEFAAICLRNALLLLPEEQQDPKQENGSKNSNQLGGNAESSESSDTCRCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTLSEMRKKPVFQPVHPIQPIQMPAFTVQRK", "length": 716, "header": "tr|A0A287A7Y4-1|A0A5G2R9Z1_PIG Computationally mapped isoform of CCR4-NOT transcription complex subunit 10 OS=Sus scrofa OX=9823 GN=CNOT10 PE=1 SV=2 CANONICAL=A0A5G2R9Z1-1" }, "locus": { "chromosome": "13", "start_pos": 18730838, "end_pos": 18649987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054328.2", "url": "https://www.ensembl.org/id/ENSSSCT00000054328.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039995.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039995.2" } ] } }, { "isoform_ac": "A0A4X1U9C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1/entry#A0A4X1U9C7-1", "sequence": { "sequence": "MAADKPSDQGAEKHEGPGQSSGITDQEKELSTNAFQAFTAGNYDVCLQHLACLQDINKDDYKIILNTAVAEFFKSNQTTTDSLRQTLNQLKNQVHSAVEEMDGLDDVENSMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQAVCFLLVDLYILTYQAEKALHLLAVLEKMISQGNNNKNGKNEAGNNTNKDTSNHKGESGALIEAAKSKIHQSAPSLFLKSNFEYLRGNYRKAVKLLNSSNIAEHPGFMKTGECLRCMFWNNLGCIHFAMSKHNLGIFYFKKALQENDNVCAQLSAGSTDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFECLIEAVQVYHANPRLWLRLAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSIQNTVYNDGQSSAIPVASMEFAAICLRNALLLLPEEQQDPKQENGSKNSNQLGGNAESSESSDTCSSKSHDGDKFIPAPPSSPLRKQELENLKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTLSEMRKKPVFQPVHPIQPIQMPAFTVQRK", "length": 715, "header": "tr|A0A4X1U9C7-1|A0A4X1U9C7_PIG Computationally mapped isoform of CCR4-NOT transcription complex subunit 10 OS=Sus scrofa OX=9823 GN=CNOT10 PE=1 SV=1 CANONICAL=A0A5G2R9Z1-1" }, "locus": { "chromosome": "13", "start_pos": 18730838, "end_pos": 18649987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056741.1", "url": "https://www.ensembl.org/id/ENSSSCT00000056741.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048821.1", "url": "https://www.ensembl.org/id/ENSSSCP00000048821.1" } ] } }, { "isoform_ac": "A0A4X1UBN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1/entry#A0A4X1UBN9-1", "sequence": { "sequence": "MAADKPSDQGAEKHEGPGQSSGITDQEKELSTNAFQAFTVHSAVEEMDGLDDVENSMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQAVCFLLVDLYILTYQAEKALHLLAVLEKMISQGNNNKNGKNEAGNNTNKDTSNHKGESGALIEAAKSKIHQYKVRAYIQMKSLKACKREIKSVMNTAGNSAPSLFLKSNFEYLRGNYRKAVKLLNSSNIAEHPGFMKTGECLRCMFWNNLGCIHFAMSKHNLGIFYFKKALQENDNVCAQLSAGSTDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFECLIEAVQVYHANPRLWLRLAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSIQNTVYNDGQSSAIPVASMEFAAICLRNALLLLPEEQQDPKQENGSKNSNQLGGNAESSESSDTCSSKSHDGDKFIPAPPSSPLRKQELENLKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTLSEMRKKPVFQPVHPIQPIQMPAFTVQRK", "length": 689, "header": "tr|A0A4X1UBN9-1|A0A4X1UBN9_PIG Computationally mapped isoform of CCR4-NOT transcription complex subunit 10 OS=Sus scrofa OX=9823 GN=CNOT10 PE=3 SV=1 CANONICAL=A0A5G2R9Z1-1" }, "locus": { "chromosome": "13", "start_pos": 18730838, "end_pos": 18649987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048586.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048586.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046057.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046057.2" } ] } }, { "isoform_ac": "A0A5G2Q7Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1/entry#A0A5G2Q7Q8-1", "sequence": { "sequence": "MLLLKNSKTCVFADQGAEKHEGPGQSSGITDQEKELSTNAFQAFTAGNYDVCLQHLACLQDINKDDYKIILNTAVAEFFKSNQTTTDSLRQTLNQLKNQVHSAVEEMDGLDDVENSMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQAVCFLLVDLYILTYQAEKALHLLAVLEKMISQGNNNKNGKNEAGNNTNKDTSNHKGESGALIEAAKSKIHQYKVRAYIQMKSLKACKREIKSVMNTAGNSAPSLFLKSNFEYLRGNYRKAVKLLNSSNIAEHPGFMKTGECLRCMFWNNLGCIHFAMSKHNLGIFYFKKALQENDNVCAQLSAGSTDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFECLIEAVQVYHANPRLWLRLAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSIQNTVYNSKSHDGDKFIPAPPSSPLRKQELENLKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTLSEMRKKPVFQPVHPIQPIQMPAFTVQRK", "length": 690, "header": "tr|A0A5G2Q7Q8-1|A0A5G2Q7Q8_PIG Computationally mapped isoform of CCR4-NOT transcription complex subunit 10 OS=Sus scrofa OX=9823 GN=CNOT10 PE=1 SV=1 CANONICAL=A0A5G2R9Z1-1" }, "locus": { "chromosome": "13", "start_pos": 18730838, "end_pos": 18664261, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075193.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075193.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059865.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059865.1" } ] } }, { "isoform_ac": "A0A5G2QS40-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1/entry#A0A5G2QS40-1", "sequence": { "sequence": "MAADKPSDQGAEKHEGPGQSSGITDQEKELSTNAFQAFTAGNYDVCLQHLACLQDINKDDYKIILNTAVAEFFKSNQTTTDSLRQTLNQLKNQVHSAVEEMDGLDDVENSMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQAVCFLLVDLYILTYQAEKALHLLAVLEKMISQGNNNKNGKNEAGNNTNKDTSNHKGESGALIEAAKSKIHQYKVRAYIQMKSLKACKREIKSVMNTAGNSAPSLFLKSNFEYLRGNYRKAVKLLNSSNIAEHPGFMKTGECLRCMFWNNLGCIHFAMSKHNLGIFYFKKALQENDNVCAQLSAGSTDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFECLIEAVQVYHANPRLWLRLAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSIQNTVYNDGQSSAIPVASMEFAAICLRNALLLLPEEQQDPKQENGSKNSNQLGGNAESSESSDTCSSKSHDGDKFIPAPPSSPLRKQELENLKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGTLRQKHWLWSLLARNSRFVVNPFANSNKNLRASFHETGM", "length": 733, "header": "tr|A0A5G2QS40-1|A0A5G2R9Z1_PIG Computationally mapped isoform of CCR4-NOT transcription complex subunit 10 OS=Sus scrofa OX=9823 GN=CNOT10 PE=1 SV=2 CANONICAL=A0A5G2R9Z1-1" }, "locus": { "chromosome": "13", "start_pos": 18731881, "end_pos": 18649987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076333.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076333.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067612.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067612.2" } ] } }, { "isoform_ac": "A0A5G2R9Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1/entry#A0A5G2R9Z1-1", "sequence": { "sequence": "MKSVGLKSVKVCASKSSVRLESQPCSLGQSRRKVKLTDNRSYTLSIGNGDYFWTSKDTLWNYVQTLSDQGAEKHEGPGQSSGITDQEKELSTNAFQAFTAGNYDVCLQHLACLQDINKDDYKIILNTAVAEFFKSNQTTTDSLRQTLNQLKNQVHSAVEEMDGLDDVENSMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQAVCFLLVDLYILTYQAEKALHLLAVLEKMISQGNNNKNGKNEAGNNTNKDTSNHKGESGALIEAAKSKIHQYKVRAYIQMKSLKACKREIKSVMNTAGNSAPSLFLKSNFEYLRGNYRKAVKLLNSSNIAEHPGFMKTGECLRCMFWNNLGCIHFAMSKHNLGIFYFKKALQENDNVCAQLSAGSTDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFECLIEAVQVYHANPRLWLRLAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSIQNTVYNDGQSSAIPVASMEFAAICLRNALLLLPEEQQDPKQENGSKNSNQLGGNAESSESSDTCSSKSHDGDKFIPAPPSSPLRKQELENLKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTLSEMRKKPVFQPVHPIQPIQMPAFTVQRK", "length": 803, "header": "tr|A0A5G2R9Z1-1|A0A5G2R9Z1_PIG Isoform 1 of CCR4-NOT transcription complex subunit 10 OS=Sus scrofa OX=9823 GN=CNOT10 PE=1 SV=1 CANONICAL=A0A5G2R9Z1-1" }, "locus": { "chromosome": "13", "start_pos": 18730838, "end_pos": 18658077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070639.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070639.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074124.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074124.1" } ] } }, { "isoform_ac": "A0A8W4FEG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1/entry#A0A8W4FEG4-1", "sequence": { "sequence": "MLLLKNSKTCVFADQGAEKHEGPGQSSGITDQEKELSTNAFQAFTAGNYDVCLQHLACLQDINKDDYKIILNTAVAEFFKSNQTTTDSLRQTLNQLKNQVHSAVEEMDGLDDVENSMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQAVCFLLVDLYILTYQAEKALHLLAVLEKMISQGNNNKNGKNEAGNNTNKDTSNHKGESGALIEAAKSKIHQYKVRAYIQMKSLKACKREIKSVMNTAGNSAPSLFLKSNFEYLRGNYRKAVKLLNSSNIAEHPGFMKTGECLRCMFWNNLGCIHFAMSKHNLGIFYFKKALQENDNVCAQLSAGSTDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFECLIEAVQVYHANPRLWLRLAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSIQNTVYNDGQSSAIPVASMEFAAICLRNALLLLPEEQQDPKQENGSKNSNQLGGNAESSESSDTCSSKSHDGDKFIPAPPSSPLRKQELENLKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGE", "length": 701, "header": "tr|A0A8W4FEG4-1|A0A5G2R9Z1_PIG Computationally mapped isoform of CCR4-NOT transcription complex subunit 10 OS=Sus scrofa OX=9823 GN=CNOT10 PE=1 SV=1 CANONICAL=A0A5G2R9Z1-1" }, "locus": { "chromosome": "13", "start_pos": 18729170, "end_pos": 18664261, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102921.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102921.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076700.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076700.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZR44", "url": "https://www.uniprot.org/uniprotkb/A0A286ZR44" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-429947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429947", "resource": "Reactome", "description": "Deadenylation of mRNA" }, { "id": "R-SSC-6804115", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804115", "resource": "Reactome", "description": "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1" } ], "pmid": "" }, { "name": "CCR4-NOT complex", "id": "GO:0030014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030014", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1" } ], "pmid": "" }, { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Z1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 658, "end_pos": 660, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9Z1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 803, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9Z1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9Z1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 658, "end_pos": 660 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RA88-1", "uniprot_ac": "A0A5G2RA88", "uniprot_id": "A0A5G2RA88_PIG", "mass": { "chemical_mass": 13607.0, "monoisotopic_mass": 13607.0 }, "refseq": { "ac": "XP_005655721", "name": "spexin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005655721" }, "gene_names": [ { "name": "GOLT1B", "type": "recommended", "evidence": [ { "id": "A0A5G2RA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88" } ] }, { "name": "SPX", "type": "recommended", "evidence": [ { "id": "A0A5G2RA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88" } ] }, { "name": "SPX", "type": "synonym", "evidence": [ { "id": "XP_005655721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005655721" }, { "id": "A0A5G2RA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88" } ] } ], "protein_names": [ { "name": "Spexin hormone", "type": "synonym", "evidence": [ { "id": "A0A5G2RA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88/entry#names_and_taxonomy" } ] }, { "name": "spexin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005655721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005655721" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GOLT1B", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88", "locus": { "chromosome": "5", "start_pos": 51939485, "end_pos": 51953315, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000579", "url": "https://www.ensembl.org/id/ENSSSCG00000000579" } ] } } ], "crossref": [ { "id": "A0A5G2RA88", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RA88", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000579", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000579", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSSSCG00000032123", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000032123", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100522076", "url": "https://www.ncbi.nlm.nih.gov/gene/100522076", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522076", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522076", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZRD5", "url": "https://www.orthodb.org/?gene=A0A286ZRD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RA88", "url": "https://www.orthodb.org/?gene=A0A5G2RA88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28590", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28590", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28590:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28590:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005655721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005655721", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZRD5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZRD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RA88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RA88-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGFRSLVVTTLALFLVFSFMGHSSSAPQRLFERRNWTPQAMLYLKGAQGRRFISNQSRRKDLSDRPPPERRSPNSQLLTLPEAVAVLLASLKKPQEAGEENFDQTRFLEDSLLNWRK", "length": 118, "header": "tr|A0A5G2RA88-1|A0A5G2RA88_PIG Isoform 1 of Spexin hormone OS=Sus scrofa OX=9823 GN=GOLT1B PE=3 SV=2 CANONICAL=A0A5G2RA88-1" }, "isoforms": [ { "isoform_ac": "A0A286ZRD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88/entry#A0A286ZRD5-1", "sequence": { "sequence": "MGHSSSAPQRLFERRNWTPQAMLYLKGAQGRRFISNQSRRKDLSDRPPPERRSPNSQLLTLPEAVAVLLASLKKPQEAGEENFDQTRFLEDSLLNWRK", "length": 98, "header": "tr|A0A286ZRD5-1|A0A5G2RA88_PIG Computationally mapped isoform of Spexin hormone OS=Sus scrofa OX=9823 GN=GOLT1B PE=3 SV=3 CANONICAL=A0A5G2RA88-1" }, "locus": { "chromosome": "5", "start_pos": 51928345, "end_pos": 51921697, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042775.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042775.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034037.3", "url": "https://www.ensembl.org/id/ENSSSCP00000034037.3" } ] } }, { "isoform_ac": "A0A5G2RA88-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88/entry#A0A5G2RA88-1", "sequence": { "sequence": "MKGFRSLVVTTLALFLVFSFMGHSSSAPQRLFERRNWTPQAMLYLKGAQGRRFISNQSRRKDLSDRPPPERRSPNSQLLTLPEAVAVLLASLKKPQEAGEENFDQTRFLEDSLLNWRK", "length": 118, "header": "tr|A0A5G2RA88-1|A0A5G2RA88_PIG Isoform 1 of Spexin hormone OS=Sus scrofa OX=9823 GN=GOLT1B PE=3 SV=2 CANONICAL=A0A5G2RA88-1" }, "locus": { "chromosome": "5", "start_pos": 51928818, "end_pos": 51921697, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068764.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068764.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067527.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067527.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZRD5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRD5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522076", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522076", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88" } ], "pmid": "" }, { "name": "dense core granule", "id": "GO:0031045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031045", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "neuropeptide hormone activity", "id": "GO:0005184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005184", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of gastro-intestinal system smooth muscle contraction", "id": "GO:1904306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904306", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA88", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RA88-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 118, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RA88-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RA88" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 }, { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RCK6-1", "uniprot_ac": "A0A5G2RCK6", "uniprot_id": "A0A5G2RCK6_PIG", "mass": { "chemical_mass": 59115.0, "monoisotopic_mass": 59115.0 }, "refseq": {}, "gene_names": [ { "name": "SLC37A3", "type": "recommended", "evidence": [ { "id": "A0A5G2RCK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6" } ] } ], "protein_names": [ { "name": "Sugar phosphate exchanger 3", "type": "recommended", "evidence": [ { "id": "A0A5G2RCK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 37 member 3", "type": "synonym", "evidence": [ { "id": "A0A5G2RCK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Unlike the other SLC37 members, lacks glucose-6-phosphate antiporter activity. In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) required for releasing N-BP molecules that have trafficked to lysosomes through fluid-phase endocytosis into the cytosol.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6#function" }, { "database": "UniProtKB", "id": "ARBA00055872", "url": "https://www.uniprot.org/uniprotkb/ARBA00055872#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC37A3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6", "locus": { "chromosome": "18", "start_pos": 9452570, "end_pos": 9383792, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000032266", "url": "https://www.ensembl.org/id/ENSSSCG00000032266" } ] } } ], "crossref": [ { "id": "A0A5G2RCK6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000032266", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000032266", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17342", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17342", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626074", "url": "https://www.ncbi.nlm.nih.gov/gene/100626074", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626074", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626074", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A480P6F2", "url": "https://www.orthodb.org/?gene=A0A480P6F2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43184", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43184", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43184:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43184:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZRG0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZRG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ALH3", "url": "https://www.uniprot.org/uniprotkb/A0A287ALH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ALH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ALH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480P6F2", "url": "https://www.uniprot.org/uniprotkb/A0A480P6F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480P6F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A480P6F2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QM59", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QM59-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBT0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWPNILQRGTLLSRFSHHHVVVFLLTFFSYSLLHASRKTFSNVKVSISKQWTPSAFNKSVDLPVEIWSRNRLFPSAEEATLFLGTLDTVFLFSYAVGLFISGIIGDRLNLRLVLSFGMCSSALVVFVFGTLTEWLHFYNKGLYCCLWIVNGLLQSTGWPCVVAVMGNWFGKAGRGVVFGLWSACASVGNILGACLASSVLQYGYEYAFLVTAAVQFAGGIVIFFGLLVSPEELGLPGIEAEENFEEDSHRPLMNGAENEDESESNYSIQEGNPVTHVQAISFYQACCLPGVIPYSLAFACLKLVNYSFFFWLPFYLSNNFGWKEAEADKLSIWYDVGGIIGGTLQGFISDVLQKRAPVLALSLLLAVGSLVGYSRSPNDKSVNALLMAVTGFFIGGPSNMISSAISADLGRQELIQGSNEALATVTGIVDGTGSIGAAVGQYLVSLIQDNLGWMWVFYFFILMTSCTILFISLAEPVPQHRPEPMQRQHWIPNPLHHSGNSRTYQKGLVSCVSVEILYESSSLARKSGRPETLRKTQ", "length": 538, "header": "tr|A0A5G2RCK6-1|A0A5G2RCK6_PIG Isoform 1 of Sugar phosphate exchanger 3 OS=Sus scrofa OX=9823 GN=SLC37A3 PE=3 SV=1 CANONICAL=A0A5G2RCK6-1" }, "isoforms": [ { "isoform_ac": "A0A286ZRG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6/entry#A0A286ZRG0-1", "sequence": { "sequence": "MAWPNILQRGTLLSRFSHHHVVVFLLTFFSYSLLHASRKTFSNVKVSISKQWTPSAFNKSVDLPVEIWSRNRLFPSAEEATLFLGTLDTVFLFSYAVVFVFGTLTEWLHFYNKGLYCCLWIVNGLLQSTGWPCVVAVMGNWFGKAGRGVVFGLWSACASVGNILGACLASSVLQYGYEYAFLVTAAVQFAGGIVIFFGLLVSPEELGLPGIEAEENFEEDSHRPLMNGAENEDESESNYSIQEGNPVTHVQAISFYQACCLPGVIPYSLAFACLKLVNYSFFFWLPFYLSNNFGWKEAEADKLSIWYDVGGIIGGTLQGFISDVLQKRAPVLALSLLLAVGSLVGYSRSPNDKSVNALLMAVTGFFIGGPSNMISSAISADLGRQELIQGSNEALATVTGIVDGTGSIGAAVGQYLVSLIQDNLGWMWVFYFFILMTSCTILFISPLIVREICSLMQRRPARLLRE", "length": 466, "header": "tr|A0A286ZRG0-1|A0A5G2RCK6_PIG Computationally mapped isoform of Sugar phosphate exchanger 3 OS=Sus scrofa OX=9823 GN=SLC37A3 PE=3 SV=2 CANONICAL=A0A5G2RCK6-1" }, "locus": { "chromosome": "18", "start_pos": 9441025, "end_pos": 9400758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055042.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055042.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034062.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034062.2" } ] } }, { "isoform_ac": "A0A287ALH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6/entry#A0A287ALH3-1", "sequence": { "sequence": "MAWPNILQRGTLLSRFSHHHVVVFLLTFFSYSLLHASRKTFSNVKVSISKQWTPSAFNKSVDLPVEIWSRNRLFPSAEEATLFLGTLDTVFLFSYAVFVFGTLTEWLHFYNKGLYCCLWIVNGLLQSTGWPCVVAVMGNWFGKAGRGVVFGLWSACASVGNILGACLASSVLQYGYEYAFLVTAAVQFAGGIVIFFGLLVSPEELGLPGIEAEENFEEDSHRPLMNGAENEDESESNYSIQEGNPVTHVQAISFYQACCLPGVIPYSLAFACLKLVNYSFFFWLPFYLSNNFGWKEAEADKLSIWYDVGGIIGGTLQGFISDVLQKRAPVLALSLLLAVGSLVGYSRSPNDKSVNALLMAVTGFFIGGPSNMISSAISADLGRQELIQGSNEALATVTGIVDGTGSIGAAVGQYLVSLIQDNLGWMWVFYFFILMTSCTILFISPLIVREICSLMQRRPARLLRE", "length": 465, "header": "tr|A0A287ALH3-1|A0A5G2RCK6_PIG Computationally mapped isoform of Sugar phosphate exchanger 3 OS=Sus scrofa OX=9823 GN=SLC37A3 PE=3 SV=3 CANONICAL=A0A5G2RCK6-1" }, "locus": { "chromosome": "18", "start_pos": 9441025, "end_pos": 9400758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064927.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064927.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044760.3", "url": "https://www.ensembl.org/id/ENSSSCP00000044760.3" } ] } }, { "isoform_ac": "A0A480P6F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6/entry#A0A480P6F2-1", "sequence": { "sequence": "MAWPNILQRGTLLSRFSHHHVVVFLLTFFSYSLLHASRKTFSNVKVSISKQWTPSAFNKSVDLPVEIWSRNRLFPSAEEATLFLGTLDTVFLFSYAVGLFISGIIGDRLNLRLVLSFGMCSSALVVFVFGTLTEWLHFYNKGLYCCLWIVNGLLQSTGWPCVVAVMGNWFGKAGRGVVFGLWSACASVGNILGACLASSVLQYGYEYAFLVTAAVQFAGGIVIFFGLLVSPEELGEEKLSPSVQKLSRLRAKRHPWPGQPSPFFPGEL", "length": 268, "header": "tr|A0A480P6F2-1|A0A480P6F2_PIG Computationally mapped isoform of Solute carrier family 37 member 3 OS=Sus scrofa OX=9823 GN=SLC37A3 PE=3 SV=1 CANONICAL=A0A5G2RCK6-1" }, "locus": { "chromosome": "18", "start_pos": 9426127, "end_pos": 9400758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068745.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068745.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064433.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064433.2" } ] } }, { "isoform_ac": "A0A5G2QM59-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6/entry#A0A5G2QM59-1", "sequence": { "sequence": "MAWPNILQRGTLLSRFSHHHVVVFLLTFFIWSRNRLFPSAEEATLFLGTLDTVFLFSYAVGLFISGIIGDRLNLRLVLSFGMCSSALVVFVFGTLTEWLHFYNKGLYCCLWIVNGLLQSTGWPCVVAVMGNWFGKAGRGVVFGLWSACASVGNILGACLASSVLQYGYEYAFLVTAAVQFAGGIVIFFGLLVSPEELGLPGIEAEENFEEDSHRPLMNGAENEDESESNYSIQEGNPVTHVQAISFYQACCLPGVIPYSLAFACLKLVNYSFFFWLPFYLSNNFGWKEAEADKLSIWYDVGGIIVFSLFDPGQPGMDVGVLLLHSYDKLYNSIYFTINSEGNMLSHAKTTSSLIERVTGAHKRTRIIGNTSGLLFLFIHPLLGLSKNSNITSDCQASFNSISRLRC", "length": 406, "header": "tr|A0A5G2QM59-1|A0A5G2RCK6_PIG Computationally mapped isoform of Sugar phosphate exchanger 3 OS=Sus scrofa OX=9823 GN=SLC37A3 PE=3 SV=2 CANONICAL=A0A5G2RCK6-1" }, "locus": { "chromosome": "18", "start_pos": 9441176, "end_pos": 9400758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087292.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087292.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065115.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065115.2" } ] } }, { "isoform_ac": "A0A5G2RCK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6/entry#A0A5G2RCK6-1", "sequence": { "sequence": "MAWPNILQRGTLLSRFSHHHVVVFLLTFFSYSLLHASRKTFSNVKVSISKQWTPSAFNKSVDLPVEIWSRNRLFPSAEEATLFLGTLDTVFLFSYAVGLFISGIIGDRLNLRLVLSFGMCSSALVVFVFGTLTEWLHFYNKGLYCCLWIVNGLLQSTGWPCVVAVMGNWFGKAGRGVVFGLWSACASVGNILGACLASSVLQYGYEYAFLVTAAVQFAGGIVIFFGLLVSPEELGLPGIEAEENFEEDSHRPLMNGAENEDESESNYSIQEGNPVTHVQAISFYQACCLPGVIPYSLAFACLKLVNYSFFFWLPFYLSNNFGWKEAEADKLSIWYDVGGIIGGTLQGFISDVLQKRAPVLALSLLLAVGSLVGYSRSPNDKSVNALLMAVTGFFIGGPSNMISSAISADLGRQELIQGSNEALATVTGIVDGTGSIGAAVGQYLVSLIQDNLGWMWVFYFFILMTSCTILFISLAEPVPQHRPEPMQRQHWIPNPLHHSGNSRTYQKGLVSCVSVEILYESSSLARKSGRPETLRKTQ", "length": 538, "header": "tr|A0A5G2RCK6-1|A0A5G2RCK6_PIG Isoform 1 of Sugar phosphate exchanger 3 OS=Sus scrofa OX=9823 GN=SLC37A3 PE=3 SV=1 CANONICAL=A0A5G2RCK6-1" }, "locus": { "chromosome": "18", "start_pos": 9451456, "end_pos": 9400758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076396.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076396.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071992.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071992.1" } ] } }, { "isoform_ac": "A0A8W4FBT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6/entry#A0A8W4FBT0-1", "sequence": { "sequence": "MAWPNILQRGTLLSRFSHHHVVVFLLTFFSYSLLHASRKTFSNVKVSISKQWTPSAFNKSVDLPVEIWSRNRLFPSAEEATLFLGTLDTVFLFSYAVGLFISGIIGDRLNLRLVLSFGMCSSALVPRGGFWSVECLCFSGQYSGSVPGFFCSTVWL", "length": 156, "header": "tr|A0A8W4FBT0-1|A0A5G2RCK6_PIG Computationally mapped isoform of Sugar phosphate exchanger 3 OS=Sus scrofa OX=9823 GN=SLC37A3 PE=3 SV=1 CANONICAL=A0A5G2RCK6-1" }, "locus": { "chromosome": "18", "start_pos": 9421488, "end_pos": 9400758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094401.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094401.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076722.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076722.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QM59", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM59" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626074", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626074", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6" } ], "pmid": "" }, { "name": "xenobiotic transmembrane transporter activity", "id": "GO:0042910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042910", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "organelle membrane", "id": "GO:0031090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031090", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "xenobiotic transmembrane transport", "id": "GO:0006855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006855", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCK6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RCK6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 538, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RCK6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCK6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RCK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCK6" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 480, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 58, "end_pos": 60 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R675-1", "uniprot_ac": "A0A5G2R675", "uniprot_id": "A0A5G2R675_PIG", "mass": { "chemical_mass": 58306.0, "monoisotopic_mass": 58306.0 }, "refseq": {}, "gene_names": [ { "name": "GFUS", "type": "recommended", "evidence": [ { "id": "A0A5G2R675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675" } ] } ], "protein_names": [ { "name": "GDP-L-fucose synthase", "type": "recommended", "evidence": [ { "id": "A0A5G2R675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.271", "type": "synonym", "evidence": [ { "id": "A0A5G2R675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675/entry#names_and_taxonomy" } ] }, { "name": "GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase", "type": "synonym", "evidence": [ { "id": "A0A5G2R675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUK6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUK6#function" }, { "database": "UniProtKB", "id": "ARBA00002870", "url": "https://www.uniprot.org/uniprotkb/ARBA00002870#function" }, { "database": "UniProtKB", "id": "A0A287B110", "url": "https://www.uniprot.org/uniprotkb/A0A287B110#function" }, { "database": "UniProtKB", "id": "A0A5G2R675", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R675", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GFUS", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675", "locus": { "chromosome": "4", "start_pos": 959744, "end_pos": 949867, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031698", "url": "https://www.ensembl.org/id/ENSSSCG00000031698" } ] } } ], "crossref": [ { "id": "A0A5G2R675", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R675", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000031698", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031698", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05239", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05239", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR43238", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43238", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43238:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43238:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6787639", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6787639", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZUK6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZUK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B110", "url": "https://www.uniprot.org/uniprotkb/A0A287B110", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B110-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B110-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R675", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R675-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRTRILVDPSQESNEESKLPHSYRLLALPLLLPDSPRRFRDVRLLRPAIAPSVPEPPLCEGEVRVRVGRGRGRTEPARTTLPRMLRGPGLHFPAAPGAPSEDSIYQRTAGGRPLVPPPPRSRRVAGESARAGSRSPGQGKVGKGAGAASMGEPQRSTRILVTGGSGLVGRAIQKVVADGARLPGEDWVFVSSKDADLTNAAQTRALFEKVQPTHVIHLAAMVGGLFRNMKYNLDFWRKNVHINDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDETMIHDGPPHSSNFGYSYAKRMIDVQNRAYFQQHGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSRGSALTVWGTGRPRRQFIYSLDLARLFLWVLREYDQVEPIILSVGEEDEVSIREAAEAVVEAMDFHGEVIFDTTKSDGQFKKTASNSKLRAYLPDFRFTPFKQGEPSRPSPGSPPSPSRGLSSLPPGGVGALQVWSPHRHHGGRRQGDCPMALGPLPTSPVASAAVKETCAWFTDNYEEARK", "length": 532, "header": "tr|A0A5G2R675-1|A0A5G2R675_PIG Isoform 1 of GDP-L-fucose synthase OS=Sus scrofa OX=9823 GN=GFUS PE=1 SV=2 CANONICAL=A0A5G2R675-1" }, "isoforms": [ { "isoform_ac": "A0A286ZUK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675/entry#A0A286ZUK6-1", "sequence": { "sequence": "MDRTRILVDPSQESNEESKLPHSYRLLALPLLLPDSPRRFRDVRLLRPAIAPSVPEPPLCEGEVRVRVGRGRGRTEPARTTLPRMLRGPGLHFPAAPGAPSEDSIYQRTAGGRPLVPPPPRSRRVAGESARAGSRSPGQGKVGKGAGAASMGEPQRSTRILVTGGSGLVGRAIQKVVADGARLPGEDWVFVSSKDADLTNAAQTRALFEKVQPTHVIHLAAMVGGLFRNMKYNLDFWRKNVHINDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDETMIHDGPPHSSNFGYSYAKRMIDVQNRAYFQQHGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSRGSALTVWGTGRPRRQFIYSLDLARLFLWVLREYDQVEPIILSVGEEDEVSIREAAEAVVEAMDFHGEVIFDTTKSDGQFKKTASNSKLRAYLPDFRFTPFKQAVKETCAWFTDNYEEARK", "length": 471, "header": "tr|A0A286ZUK6-1|A0A5G2R675_PIG Computationally mapped isoform of GDP-L-fucose synthase OS=Sus scrofa OX=9823 GN=GFUS PE=1 SV=2 CANONICAL=A0A5G2R675-1" }, "locus": { "chromosome": "4", "start_pos": 955558, "end_pos": 950066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056191.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056191.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035334.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035334.2" } ] } }, { "isoform_ac": "A0A287B110-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675/entry#A0A287B110-1", "sequence": { "sequence": "MDRTRILVDPSQESNEESKLPHSYRLLALPLLLPDSPRRFRDVRLLRPAIAPSVPEPPLCEGEVRVRVGRGRGRTEPARTTLPRMLRGPGLHFPAAPGAPSEDSIYQRTAGGRPLVPPPPRSRRVAGESARAGSRSPGQGKVGKGAGAASMGEPQRSTRILVTGGSGLVGRAIQKVVADGARLPGEDWVFVSSKDADLTNAAQTRALFEKVQPTHVIHLAAMVGGLFRNMKYNLDFWRKNVHINDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDETMIHDGPPHSSNFGYSYAKRMIDVQNRAYFQQHGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSRGSALTVWGTGRPRRQFIYSLDLARLFLWVLREYDQVEPIILSVGEEDEVSIREAAEAVVEAMDFHGEVIFDTTKSDGQFKKTASNSKLRAYLPDFRFTPFKQESGHFTRPGSSAAQWPPSVVRRLCRIPARDPA", "length": 485, "header": "tr|A0A287B110-1|A0A5G2R675_PIG Computationally mapped isoform of GDP-L-fucose synthase OS=Sus scrofa OX=9823 GN=GFUS PE=1 SV=3 CANONICAL=A0A5G2R675-1" }, "locus": { "chromosome": "4", "start_pos": 959499, "end_pos": 950066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042851.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042851.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049911.3", "url": "https://www.ensembl.org/id/ENSSSCP00000049911.3" } ] } }, { "isoform_ac": "A0A5G2R675-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675/entry#A0A5G2R675-1", "sequence": { "sequence": "MDRTRILVDPSQESNEESKLPHSYRLLALPLLLPDSPRRFRDVRLLRPAIAPSVPEPPLCEGEVRVRVGRGRGRTEPARTTLPRMLRGPGLHFPAAPGAPSEDSIYQRTAGGRPLVPPPPRSRRVAGESARAGSRSPGQGKVGKGAGAASMGEPQRSTRILVTGGSGLVGRAIQKVVADGARLPGEDWVFVSSKDADLTNAAQTRALFEKVQPTHVIHLAAMVGGLFRNMKYNLDFWRKNVHINDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDETMIHDGPPHSSNFGYSYAKRMIDVQNRAYFQQHGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSRGSALTVWGTGRPRRQFIYSLDLARLFLWVLREYDQVEPIILSVGEEDEVSIREAAEAVVEAMDFHGEVIFDTTKSDGQFKKTASNSKLRAYLPDFRFTPFKQGEPSRPSPGSPPSPSRGLSSLPPGGVGALQVWSPHRHHGGRRQGDCPMALGPLPTSPVASAAVKETCAWFTDNYEEARK", "length": 532, "header": "tr|A0A5G2R675-1|A0A5G2R675_PIG Isoform 1 of GDP-L-fucose synthase OS=Sus scrofa OX=9823 GN=GFUS PE=1 SV=2 CANONICAL=A0A5G2R675-1" }, "locus": { "chromosome": "4", "start_pos": 955558, "end_pos": 950066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081975.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081975.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072751.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072751.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUK6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUK6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6787639", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6787639", "resource": "Reactome", "description": "GDP-fucose biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "'de novo' GDP-L-fucose biosynthetic process", "id": "GO:0042351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R675", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GDP-L-fucose synthase activity", "id": "GO:0050577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050577", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R675", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675" } ], "pmid": "" }, { "name": "isomerase activity", "id": "GO:0016853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016853", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R675", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-6787623", "name": "GFUS dimer epimerises GDP-DHDMan to GDP-KDGal", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6787623", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6787623" } ] }, { "id": "R-SSC-6787642", "name": "GFUS dimer reduces GDP-KDGal to GDP-Fuc", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-6787646" ], "output_participant_list": [ "R-ALL-742368" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6787642", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6787642" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6787646", "participant_name": "GDP-KDGal [cytosol]", "crossref": [ { "id": "746915", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-742368", "participant_name": "GDP-Fuc [cytosol]", "crossref": [ { "id": "ZINC000008551145", "database": "ZINC", "url": "" }, { "id": "57273", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R675-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 532, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R675-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R675" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R675" }, { "id": "PF01370", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01370" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NAD-dependent epimerase/dehydratase", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 395, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAW8-1", "uniprot_ac": "A0A5G2RAW8", "uniprot_id": "A0A5G2RAW8_PIG", "mass": { "chemical_mass": 77185.0, "monoisotopic_mass": 77185.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Cullin family profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RAW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAW8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8", "locus": {} } ], "crossref": [ { "id": "A0A5G2RAW8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000035670", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035670", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00888", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00888", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287A5H5", "url": "https://www.uniprot.org/uniprotkb/A0A287A5H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A5H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A5H5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AJC8", "url": "https://www.uniprot.org/uniprotkb/A0A287AJC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AJC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QC53", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QC53-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIG0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4L9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAW8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFCPLFLLSLLSYCRYFNCSRFVFVSNFPRLVWLWQMVNCSAVGALYFFFFPHFLSLTFSVSLFLACIFHSLLFFNFCYVVFPSYICLLQFTPGLKTISIFLAFVGPNVKMAEEYASPSSTASQEEEQLKNRNLIIYSMAEEYHTDALTKPPMTLSSFVNIKPSTGSVKKLVIRNFKDKPLMLENYTEETWQKLKEAVQAIQNNISVKYSLEELYQSVENLCSYDLSANLYKQLKQLCENHIKVQIHQFRDDSFLKEMDRCWQNYGRQMIMIRNIFLFLDRTYVFQISMLSSIWDMGLELFKSYIICDQKVQNRTIHGILLLIEKERNGEMVDRSLIQRLLTMLSDLQIYQESFENKFLEETSRFYASEGRKLVQKREVLEIKIVINLFMVHRLSKDIMIQLKQYMQNQDIPGNIDLTVNILTTSFWPAYVPKEIQLPPEMERLKENFKNFYLSKHSGRKLQWQSTLGHCVLRAEFKKGKKELQVSLFQTLVLLMFNEGDQFSLEEIKMTTGVEDRELRRTLQSLACGRARVLIKNPKGKDVESGDRFFCNEEFRHKLFKIKINQIQMKETVEEQTVTTERVFQDRQYQIDAAIVRIMKIRKTLSHNVLLAELYNQLKFTLKPSDLKKRIESLIDRDYMERDKANPNQYKYIA", "length": 653, "header": "tr|A0A5G2RAW8-1|A0A5G2RAW8_PIG Isoform 1 of Cullin family profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RAW8-1" }, "isoforms": [ { "isoform_ac": "A0A287A5H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8/entry#A0A287A5H5-1", "sequence": { "sequence": "MAEEYASPSSTASQEEEQLKNRNLIIYSMAEEYHTDALTKPPMTLSSFVNIKPSTGSVKKLVIRNFKDKPLMLENYTEETWQKLKEAVQAIQNNISVKYSLEELYQSVENLCSYDLSANLYKQLKQLCENHIKVQIHQFRDDSFLKEMDRCWQNYGRQMIMIRNIFLFLDRTYVFQISMLSSIWDMGLELFKSYIICDQKVQNRTIHGILLLIEKERNGEMVDRSLIQRLLTMLSDLQVKSFENKFLEETSRFYASEGRKLVQKREIPGCLYYIKKLLEEEVDRVRTYLRLNTQKLLIAIVEKQLLGEHLSAVLQKGKFKFILKYFTECGTAFTNKLQGMFKDMELSKDIMIQLKQYMQNQDIPGNIDLTVNILTTSFWPAYVPKEIQLPPEMERLKENFKNFYLSKHSGRKLQWQSTLGHCVLRAEFKKGKKELQVSLFQTLVLLMFNEGDQFSLEEIKMTTGVEDRELRRTLQSLACGRARVLIKNPKGKDVESGDRFFCNEEFRHKLFKIKINQIQMKETVEEQTVTTERVFQDRQYQIDAAIVRIMKIRKTLSHNVLLAELYNQLKFTLKPSDLKKRIESLIDRDYMERDKANPNQYKYIA", "length": 605, "header": "tr|A0A287A5H5-1|A0A5G2RAW8_PIG Computationally mapped isoform of Cullin family profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RAW8-1" }, "locus": { "chromosome": "Y", "start_pos": 40752960, "end_pos": 40605607, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064056.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064056.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039016.1", "url": "https://www.ensembl.org/id/ENSSSCP00000039016.1" } ] } }, { "isoform_ac": "A0A287AJC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8/entry#A0A287AJC8-1", "sequence": { "sequence": "MAEEYASPSSTASQEEEQLKNRNLIIYSMAEEYHTDALTKPPMTLSSFVNIKPSTGSVKKLVIRNFKDKPLMLENYTEETWQKLKEAVQAIQNNISVKYSLEELYQSVENLCSYDLSANLYKQLKQLCENHIKVQIHQFRDDSFLKEMDRCWQNYGRQMIMIRNIFLFLDRTYVFQISMLSSIWDMGLELFKSYIICDQKVQNRTIHGILLLIEKERNGEMVDRSLIQRLLTMLSDLQIYQESFENKFLEETSRFYASEGRKLVQKREIPGCLYYIKKLLEEEVDRVRTYLRLNTQKLLIAIVEKQLLGEHLSAVLQKGKFKCVFKYYHGKIHTKMLYTILTVFARFLMVSFHEMSLKNILLFILKYFTECGTAFTNKLQGMFKDMELSKDIMIQLKQYMQNQDIPGNIDLTVNILTTSFWPAYVPKEIQLPPEMERLKENFKNFYLSKHSGRKLQWQSTLGHCVLRAEFKKGKKELQVSLFQTLVLLMFNEGDQFSLEEIKMTTGVEDRELRRTLQSLACGRARVLIKNPKGKDVESGDRFFCNEEFRHKLFKIKINQIQMKETVEEQTVTTERVFQDRQYQIDAAIVRIMKIRKTLSHNVLLAELYNQLKFTLKPSDLKKRIESLIDRDYMERDKANPNQYKYIA", "length": 647, "header": "tr|A0A287AJC8-1|A0A5G2RAW8_PIG Computationally mapped isoform of Cullin family profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RAW8-1" }, "locus": { "chromosome": "Y", "start_pos": 40752960, "end_pos": 40605607, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060315.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060315.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043995.2", "url": "https://www.ensembl.org/id/ENSSSCP00000043995.2" } ] } }, { "isoform_ac": "A0A5G2QC53-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8/entry#A0A5G2QC53-1", "sequence": { "sequence": "IVGPFPVYCGFPPPAILCLEFDVCQIFLNLSKMRIGSIFLAFVGPNVKMAEEYASPSSTASQEEEQLKNRNLIIYSMAEEYHTDALTKPPMTLSSFVNIKPSTGSVKKLVIRNFKDKPLMLENYTEETWQKLKEAVQAIQNNISVKYSLEELYQSVENLCSYDLSANLYKQLKQLCENHIKVQIHQFRDDSFLKEMDRCWQNYGRQMIMIRNIFLFLDRTYVFQISMLSSIWDMGLELFKSYIICDQKVQNRTIHGILLLIEKERNGEMVDRSLIQRLLTMLSDLQIYQESFENKFLEETSRFYASEGRKLVQKREVLEIKIVINLFMVHRLSKDIMIQLKQYMQNQDIPGNIDLTVNILTTSFWPAYVPKEIQLPPEMERLKENFKNFYLSKHSGRKLQWQSTLGHCVLRAEFKKGKKELQVSLFQTLVLLMFNEGDQFSLEEIKMTTGVEDRELRRTLQSLACGRARVLIKNPKGKDVESGDRFFCNEEFRHKLFKIKINQIQMKETVEEQTVTTERVFQDRQYQIDAAIVRIMKIRKTLSHNVLLAELYNQLKFTLKPSDLKKRIESLIDRDYMERDKANPNQYKYIA", "length": 591, "header": "tr|A0A5G2QC53-1|A0A5G2QC53_PIG Computationally mapped isoform of Cullin family profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RAW8-1" }, "locus": { "chromosome": "Y", "start_pos": 40752960, "end_pos": 40604796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090125.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090125.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061099.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061099.1" } ] } }, { "isoform_ac": "A0A5G2QIG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8/entry#A0A5G2QIG0-1", "sequence": { "sequence": "MIVYGYVSSDILPCYVFCFLSGFSHFLFIPLSLSLHIFLAFVGPNVKMAEEYASPSSTASQEEEQLKNRNLIIYSMAEEYHTDALTKPPMTLSSFVNIKPSTGSVKKLVIRNFKDKPLMLENYTEETWQKLKEAVQAIQNNISVKYSLEELYQSVENLCSYDLSANLYKQLKQLCENHIKVQIHQFRDDSFLKEMDRCWQNYGRQMIMIRNIFLFLDRTYVFQISMLSSIWDMGLELFKSYIICDQKVQNRTIHGILLLIEKERNGEMVDRSLIQRLLTMLSDLQIYQESFENKFLEETSRFYASEGRKLVQKREVLEIKIVINLFMVHRLSKDIMIQLKQYMQNQDIPGNIDLTVNILTTSFWPAYVPKEIQLPPEMERLKENFKNFYLSKHSGRKLQWQSTLGHCVLRAEFKKGKKELQVSLFQTLVLLMFNEGDQFSLEEIKMTTGVEDRELRRTLQSLACGRARVLIKNPKGKDVESGDRFFCNEEFRHKLFKIKINQIQMKETVEEQTVTTERVFQDRQYQIDAAIVRIMKIRKTLSHNVLLAELYNQLKFTLKPSDLKKRIESLIDRDYMERDKANPNQYKYIA", "length": 590, "header": "tr|A0A5G2QIG0-1|A0A5G2QIG0_PIG Computationally mapped isoform of Cullin family profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RAW8-1" }, "locus": { "chromosome": "Y", "start_pos": 40752960, "end_pos": 40604638, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066861.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066861.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063686.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063686.1" } ] } }, { "isoform_ac": "A0A5G2QMC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8/entry#A0A5G2QMC5-1", "sequence": { "sequence": "MAEEYASPSSTASQEEEQLKNRNLIIYSMAEEYHTDALTKPPMTLSSFVNIKPSTGSVKKLVIRNFKDKPLMLENYTEETWQKLKEAVQAIQNNISVKYSLEELYQSVENLCSYDLSANLYKQLKQLCENHIKVQIHQFRDDSFLKEMDRCWQNYGRQMIMIRNIFLFLDRTYVFQISMLSSIWDMGLELFKSYIICDQKVQNRTIHGILLLIEKERNGEMVDRSLIQRLLTMLSDLQIYQESFENKFLEETSRFYASEGRKLVQKREIPGCLYYIKKLLEEEVDRVRTYLRLNTQKLLIAIVEKQLLGEHLSAVLQKGKFKCVFKYYHGKIHTKMLYTVSYVSVEKSAVIILKYFTECGTAFTNKLQGMFKDMELSKDIMIQLKQYMQNQDIPGNIDLTVNILTTSFWPAYVPKEIQLPPEMERLKENFKNFYLSKHSGRKLQWQSTLGHCVLRAEFKKGKKELQVSLFQTLVLLMFNEGDQFSLEEIKMTTGVEDRELRRTLQSLACGRARVLIKNPKGKDVESGDRFFCNEEFRHKLFKIKINQIQMKETVFVFSSS", "length": 560, "header": "tr|A0A5G2QMC5-1|A0A5G2RAW8_PIG Computationally mapped isoform of Cullin family profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RAW8-1" }, "locus": { "chromosome": "Y", "start_pos": 40701358, "end_pos": 40605607, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076027.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076027.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065768.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065768.1" } ] } }, { "isoform_ac": "A0A5G2QVY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8/entry#A0A5G2QVY0-1", "sequence": { "sequence": "MAEEYASPSSTASQEEEQLKNRNLIIYSMAEEYHTDALTKPPMTLSSFVNIKPSTGSVKKLVIRNFKDKPLMLENYTEETWQKLKEAVQAIQNNISVKYSLEELYQSVENLCSYDLSANLYKQLKQLCENHIKVQIHQFRDDSFLKEMDRCWQNYGRQMIMIRNIFLFLDRTYVFQISMLSSIWDMGLELFKSYIICDQKVQNRTIHGILLLIEKERNGEMVDRSLIQRLLTMLSDLQIYQESFENKFLEETSRFYASEGRKLVQKREIPGCLYYIKKLLEEEVDRVRTYLRLNTQKLLIAIVEKQLLGEHLSAVLQKGKFKCYSCENFCCTKKWLSHIYNHIHFSQILFQHMPDYRILGGVLFILKYFTECGTAFTNKLQGMFKDMELSKDIMIQLKQYMQNQDIPGNIDLTVNILTTSFWPAYVPKEIQLPPEMERLKENFKNFYLSKHSGRKLQWQSTLGHCVLRAEFKKGKKELQVSLFQTLVLLMFNEGDQFSLEEIKMTTGVEDRELRRTLQSLACGRARVLIKNPKGKDVESGDRFFCNEEFRHKLFKIKINQIQMKETVFVFSSS", "length": 573, "header": "tr|A0A5G2QVY0-1|A0A5G2RAW8_PIG Computationally mapped isoform of Cullin family profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RAW8-1" }, "locus": { "chromosome": "Y", "start_pos": 40701358, "end_pos": 40605607, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088994.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088994.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069109.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069109.1" } ] } }, { "isoform_ac": "A0A5G2R4L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8/entry#A0A5G2R4L9-1", "sequence": { "sequence": "MQCVVESHLLFHLSCSFSFDLSCFFLFCFGIYSSVYYIFLAFVGPNVKMAEEYASPSSTASQEEEQLKNRNLIIYSMAEEYHTDALTKPPMTLSSFVNIKPSTGSVKKLVIRNFKDKPLMLENYTEETWQKLKEAVQAIQNNISVKYSLEELYQSVENLCSYDLSANLYKQLKQLCENHIKVQIHQFRDDSFLKEMDRCWQNYGRQMIMIRNIFLFLDRTYVFQISMLSSIWDMGLELFKSYIICDQKVQNRTIHGILLLIEKERNGEMVDRSLIQRLLTMLSDLQIYQESFENKFLEETSRFYASEGRKLVQKREVLEIKIVINLFMVHRLSKDIMIQLKQYMQNQDIPGNIDLTVNILTTSFWPAYVPKEIQLPPEMERLKENFKNFYLSKHSGRKLQWQSTLGHCVLRAEFKKGKKELQVSLFQTLVLLMFNEGDQFSLEEIKMTTGVEDRELRRTLQSLACGRARVLIKNPKGKDVESGDRFFCNEEFRHKLFKIKINQIQMKETVEEQTVTTERVFQDRQYQIDAAIVRIMKIRKTLSHNVLLAELYNQLKFTLKPSDLKKRIESLIDRDYMERDKANPNQYKYIA", "length": 591, "header": "tr|A0A5G2R4L9-1|A0A5G2RAW8_PIG Computationally mapped isoform of Cullin family profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RAW8-1" }, "locus": { "chromosome": "Y", "start_pos": 40752960, "end_pos": 40605297, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078243.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078243.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072031.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072031.1" } ] } }, { "isoform_ac": "A0A5G2RAW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8/entry#A0A5G2RAW8-1", "sequence": { "sequence": "MFCPLFLLSLLSYCRYFNCSRFVFVSNFPRLVWLWQMVNCSAVGALYFFFFPHFLSLTFSVSLFLACIFHSLLFFNFCYVVFPSYICLLQFTPGLKTISIFLAFVGPNVKMAEEYASPSSTASQEEEQLKNRNLIIYSMAEEYHTDALTKPPMTLSSFVNIKPSTGSVKKLVIRNFKDKPLMLENYTEETWQKLKEAVQAIQNNISVKYSLEELYQSVENLCSYDLSANLYKQLKQLCENHIKVQIHQFRDDSFLKEMDRCWQNYGRQMIMIRNIFLFLDRTYVFQISMLSSIWDMGLELFKSYIICDQKVQNRTIHGILLLIEKERNGEMVDRSLIQRLLTMLSDLQIYQESFENKFLEETSRFYASEGRKLVQKREVLEIKIVINLFMVHRLSKDIMIQLKQYMQNQDIPGNIDLTVNILTTSFWPAYVPKEIQLPPEMERLKENFKNFYLSKHSGRKLQWQSTLGHCVLRAEFKKGKKELQVSLFQTLVLLMFNEGDQFSLEEIKMTTGVEDRELRRTLQSLACGRARVLIKNPKGKDVESGDRFFCNEEFRHKLFKIKINQIQMKETVEEQTVTTERVFQDRQYQIDAAIVRIMKIRKTLSHNVLLAELYNQLKFTLKPSDLKKRIESLIDRDYMERDKANPNQYKYIA", "length": 653, "header": "tr|A0A5G2RAW8-1|A0A5G2RAW8_PIG Isoform 1 of Cullin family profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RAW8-1" }, "locus": { "chromosome": "Y", "start_pos": 40752960, "end_pos": 40604977, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069175.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069175.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074147.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074147.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAW8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAW8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAW8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cullin-RING ubiquitin ligase complex", "id": "GO:0031461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031461", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAW8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAW8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 653, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAW8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAW8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAW8" }, { "id": "PS50069", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50069" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cullin family profile", "eco_id": "ECO_0000259", "start_pos": 348, "end_pos": 526, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 }, { "start_pos": 18, "end_pos": 20 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2R6T7-1", "uniprot_ac": "A0A5G2R6T7", "uniprot_id": "A0A5G2R6T7_PIG", "mass": { "chemical_mass": 100986.0, "monoisotopic_mass": 100986.0 }, "refseq": {}, "gene_names": [ { "name": "ACTN1", "type": "recommended", "evidence": [ { "id": "A0A5G2R6T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ] } ], "protein_names": [ { "name": "F-actin cross-linking protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R6T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ACTN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7", "locus": { "chromosome": "7", "start_pos": 92550007, "end_pos": 92644842, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036702", "url": "https://www.ensembl.org/id/ENSSSCG00000036702" } ] } } ], "crossref": [ { "id": "A0A5G2R6T7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6T7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000036702", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036702", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00176", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00176", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21216", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21216", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11915", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11915", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00435", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00435", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08726", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08726", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13405", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13405", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-446388", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446388", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013418", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013418", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMI4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LLY3", "url": "https://www.uniprot.org/uniprotkb/I3LLY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LLY3-1", "url": "https://www.uniprot.org/uniprotkb/I3LLY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDHYDSQQTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKVPGAPCSFLAQHTSCQTLIHALPPLLPLPRLGDRTWAQKAGMEGKGRNMQTALGGGSILGSLGRRERPTLHVHFGKLRSFSSFQAESAAFRGPELLLAEGALCFKDINNAWGCLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRKKTGMMDTDDFRACLISMGYNMGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITVDELRRELPPDQAEYCIARMAPYTGPDAVPGALDYMSFSTALYGESDL", "length": 884, "header": "tr|A0A5G2R6T7-1|A0A5G2R6T7_PIG Isoform 1 of F-actin cross-linking protein OS=Sus scrofa OX=9823 GN=ACTN1 PE=1 SV=2 CANONICAL=A0A5G2R6T7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R6T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7/entry#A0A5G2R6T7-1", "sequence": { "sequence": "MDHYDSQQTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKVPGAPCSFLAQHTSCQTLIHALPPLLPLPRLGDRTWAQKAGMEGKGRNMQTALGGGSILGSLGRRERPTLHVHFGKLRSFSSFQAESAAFRGPELLLAEGALCFKDINNAWGCLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRKKTGMMDTDDFRACLISMGYNMGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITVDELRRELPPDQAEYCIARMAPYTGPDAVPGALDYMSFSTALYGESDL", "length": 884, "header": "tr|A0A5G2R6T7-1|A0A5G2R6T7_PIG Isoform 1 of F-actin cross-linking protein OS=Sus scrofa OX=9823 GN=ACTN1 PE=1 SV=2 CANONICAL=A0A5G2R6T7-1" }, "locus": { "chromosome": "7", "start_pos": 92644567, "end_pos": 92550707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082067.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082067.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072795.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072795.2" } ] } }, { "isoform_ac": "A0A8W4FMI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7/entry#A0A8W4FMI4-1", "sequence": { "sequence": "MDHYDSQQTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKDINNAWGCLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQKKTGMMDTDDFRACLISMGYNMGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITVDELRRELPPDQAEYCIARMAPYTGPDAVPGALDYMSFSTALYGESDL", "length": 806, "header": "tr|A0A8W4FMI4-1|A0A5G2R6T7_PIG Computationally mapped isoform of F-actin cross-linking protein OS=Sus scrofa OX=9823 GN=ACTN1 PE=1 SV=1 CANONICAL=A0A5G2R6T7-1" }, "locus": { "chromosome": "7", "start_pos": 92644567, "end_pos": 92550707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103147.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103147.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079524.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079524.1" } ] } }, { "isoform_ac": "I3LLY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7/entry#I3LLY3-1", "sequence": { "sequence": "MDHYDSQQTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKATVAAAPLCPLLYLNQQNRKYLYHSHSNVDLSGICDLHCSLWQHQILNPLSEPTPQPQQHRMLNSLNEARDREKFYEPEKHTKENCKIHQSFSSFQAESAAFRGPELLLAEGALCFDINNAWGCLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRKKTGMMDTDDFRACLISMGYNMGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITVDELRRELPPDQAEYCIARMAPYTGPDAVPGALDYMSFSTALYGESDL", "length": 895, "header": "tr|I3LLY3-1|A0A5G2R6T7_PIG Computationally mapped isoform of F-actin cross-linking protein OS=Sus scrofa OX=9823 GN=ACTN1 PE=1 SV=2 CANONICAL=A0A5G2R6T7-1" }, "locus": { "chromosome": "7", "start_pos": 92644567, "end_pos": 92550707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027004.4", "url": "https://www.ensembl.org/id/ENSSSCT00000027004.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025103.3", "url": "https://www.ensembl.org/id/ENSSSCP00000025103.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LLY3", "url": "https://www.uniprot.org/uniprotkb/I3LLY3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" }, { "id": "R-SSC-446388", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446388", "resource": "Reactome", "description": "Regulation of cytoskeletal remodeling and cell spreading by IPP complex components" }, { "id": "R-SSC-9013418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013418", "resource": "Reactome", "description": "RHOBTB2 GTPase cycle" }, { "id": "R-SSC-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "vinculin binding", "id": "GO:0017166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017166", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "structural constituent of postsynapse", "id": "GO:0099186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "fascia adherens", "id": "GO:0005916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005916", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "focal adhesion assembly", "id": "GO:0048041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048041", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "platelet formation", "id": "GO:0030220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030220", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "actin filament network formation", "id": "GO:0051639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051639", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" }, { "name": "muscle cell development", "id": "GO:0055001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055001", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R6T7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 884, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R6T7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6T7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R6T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 135, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R6T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6T7" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 743, "end_pos": 778, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 704, "end_pos": 706 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RBY0-1", "uniprot_ac": "A0A5G2RBY0", "uniprot_id": "A0A5G2RBY0_PIG", "mass": { "chemical_mass": 27907.0, "monoisotopic_mass": 27907.0 }, "refseq": {}, "gene_names": [ { "name": "GCLM", "type": "recommended", "evidence": [ { "id": "A0A5G2RBY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0" } ] } ], "protein_names": [ { "name": "Glutamate--cysteine ligase regulatory subunit", "type": "recommended", "evidence": [ { "id": "A0A5G2RBY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0/entry#names_and_taxonomy" } ] }, { "name": "GCS light chain", "type": "synonym", "evidence": [ { "id": "A0A5G2RBY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0/entry#names_and_taxonomy" } ] }, { "name": "Gamma-ECS regulatory subunit", "type": "synonym", "evidence": [ { "id": "A0A5G2RBY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0/entry#names_and_taxonomy" } ] }, { "name": "Gamma-glutamylcysteine synthetase regulatory subunit", "type": "synonym", "evidence": [ { "id": "A0A5G2RBY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0/entry#names_and_taxonomy" } ] }, { "name": "Glutamate--cysteine ligase modifier subunit", "type": "synonym", "evidence": [ { "id": "A0A5G2RBY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GCLM", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0", "locus": { "chromosome": "4", "start_pos": 123390131, "end_pos": 123371193, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037549", "url": "https://www.ensembl.org/id/ENSSSCG00000037549" } ] } } ], "crossref": [ { "id": "A0A5G2RBY0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000037549", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037549", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100153977", "url": "https://www.ncbi.nlm.nih.gov/gene/100153977", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153977", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153977", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHEWIPL", "url": "https://omabrowser.org/oma/group/AHEWIPL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287AA47", "url": "https://www.orthodb.org/?gene=A0A287AA47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13295", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13295", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13295:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13295:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-174403", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174403", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AA47", "url": "https://www.uniprot.org/uniprotkb/A0A287AA47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AA47-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AA47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTDSRAAGALLARASTLHLQTGNLLNWGRLRKKCPSTHSEEEFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVGSNSSSSTKSAVDMACSVLGVAQLDSVIIASPPVEDGVHLSLEHLQPYWEELQDLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIEAHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRKSS", "length": 252, "header": "tr|A0A5G2RBY0-1|A0A5G2RBY0_PIG Isoform 1 of Glutamate--cysteine ligase regulatory subunit OS=Sus scrofa OX=9823 GN=GCLM PE=3 SV=1 CANONICAL=A0A5G2RBY0-1" }, "isoforms": [ { "isoform_ac": "A0A287AA47-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0/entry#A0A287AA47-1", "sequence": { "sequence": "MGTDSRAAGALLARASTLHLQTGNLLNWGRLRKKCPSTHSEELRDCIQKTLNEWSSQISPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVGSNSSSSTKSAVDMACSVLGVAQLDSVIIASPPVEDGVHLSLEHLQPYWEELQDLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIEAHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRKSS", "length": 274, "header": "tr|A0A287AA47-1|A0A5G2RBY0_PIG Computationally mapped isoform of Glutamate--cysteine ligase regulatory subunit OS=Sus scrofa OX=9823 GN=GCLM PE=3 SV=1 CANONICAL=A0A5G2RBY0-1" }, "locus": { "chromosome": "4", "start_pos": 123386215, "end_pos": 123371565, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061853.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061853.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040673.1", "url": "https://www.ensembl.org/id/ENSSSCP00000040673.1" } ] } }, { "isoform_ac": "A0A5G2RBY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0/entry#A0A5G2RBY0-1", "sequence": { "sequence": "MGTDSRAAGALLARASTLHLQTGNLLNWGRLRKKCPSTHSEEEFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVGSNSSSSTKSAVDMACSVLGVAQLDSVIIASPPVEDGVHLSLEHLQPYWEELQDLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIEAHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRKSS", "length": 252, "header": "tr|A0A5G2RBY0-1|A0A5G2RBY0_PIG Isoform 1 of Glutamate--cysteine ligase regulatory subunit OS=Sus scrofa OX=9823 GN=GCLM PE=3 SV=1 CANONICAL=A0A5G2RBY0-1" }, "locus": { "chromosome": "4", "start_pos": 123386215, "end_pos": 123371565, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067689.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067689.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071697.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071697.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AA47", "url": "https://www.uniprot.org/uniprotkb/A0A287AA47" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153977", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153977", "resource": "KEGG Pathway" }, { "id": "R-SSC-174403", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174403", "resource": "Reactome", "description": "Glutathione synthesis and recycling" } ], "orthologs": [ { "uniprot_canonical_ac": "O09172-1", "protein_name": "Glutamate--cysteine ligase regulatory subunit", "gene_name": "Gclm", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTDSRAAGALLARASTLHLQTGNLLNWGRLRKKCPSTHSEELRDCIQKTLNEWSSQISPDLVREFPDVLECTMSHAVEKINPDEREEMKVSAKLFIVGSNSSSSTRSAVDMACSVLGVAQLDSVIMASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIEAQDWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS", "length": 274 }, "evidence": [ { "id": "A0A5G2RBY0", "url": "https://omabrowser.org/oma/group/A0A5G2RBY0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P48507-1", "protein_name": "Glutamate--cysteine ligase regulatory subunit", "gene_name": "GCLM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQAHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS", "length": 274 }, "evidence": [ { "id": "A0A5G2RBY0", "url": "https://omabrowser.org/oma/group/A0A5G2RBY0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P48508-1", "protein_name": "Glutamate--cysteine ligase regulatory subunit", "gene_name": "Gclm", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTDSRAAGALLARASTLHLQTGNLLNWGRLRKKCPSTHSEELRDCIQKTLNEWSSQISPDLVREFPDVLECTMSHAVEKINPDEREEMKVSAKLFIVGSNSSSSTRNAVDMACSVLGVAQLDSVIMASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIEAQEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRKGS", "length": 274 }, "evidence": [ { "id": "A0A5G2RBY0", "url": "https://omabrowser.org/oma/group/A0A5G2RBY0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2T9Y6-1", "protein_name": "Glutamate--cysteine ligase regulatory subunit", "gene_name": "GCLM", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGTDSRAAGALLARASTLHLQTGNLLNWGRLRKKCPSTHSEELRDCIQKTLNEWSSQISPDLIREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVGSNSSSSTRNAVDMACSVLGVAQLDSVIIASPPVEDGVNLSLEHLQPYWEELQNLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIRAHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRKGS", "length": 274 }, "evidence": [ { "id": "A0A5G2RBY0", "url": "https://omabrowser.org/oma/group/A0A5G2RBY0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9VCW6-1", "protein_name": "GCS light chain", "gene_name": "Gclm", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIPTITKKYQNVVISTGNIIATELGQRKSNEELYDGLKITLHTDSTAERVVVEKEIDELHGRVQRATQELTTRLTENGRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVLAYHPNAVATATPVATTKPPCSEDSNVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQITQLGIADLDAAALEELHNSAQVVPTIAQVNLSTCCVVPPELQEFCTAHDIQLNTHSDPELLLPVEQFDGLVPGYTIDWTLRYQVHVRCRGVLTAKGYIVGASRSSV", "length": 285 }, "evidence": [ { "id": "A0A5G2RBY0", "url": "https://omabrowser.org/oma/group/A0A5G2RBY0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "glutathione biosynthetic process", "id": "GO:0006750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006750", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0" } ], "pmid": "" }, { "name": "glutamate metabolic process", "id": "GO:0006536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006536", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0" } ], "pmid": "" }, { "name": "blood vessel diameter maintenance", "id": "GO:0097746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097746", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "glutamate-cysteine ligase complex", "id": "GO:0017109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017109", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "glutamate-cysteine ligase catalytic subunit binding", "id": "GO:0035226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035226", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0" } ], "pmid": "" }, { "name": "glutamate-cysteine ligase activity", "id": "GO:0004357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0" } ], "pmid": "" }, { "name": "glutamate-cysteine ligase regulator activity", "id": "GO:1990609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990609", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RBY0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 252, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RBY0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBY0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RBY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBY0" }, { "id": "PF00248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NADP-dependent oxidoreductase", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 190, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7X3-1", "uniprot_ac": "A0A5G2R7X3", "uniprot_id": "A0A5G2R7X3_PIG", "mass": { "chemical_mass": 55121.0, "monoisotopic_mass": 55121.0 }, "refseq": {}, "gene_names": [ { "name": "EIF3L", "type": "recommended", "evidence": [ { "id": "A0A5G2R7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ] }, { "name": "EIF3EIP", "type": "synonym", "evidence": [ { "id": "A0A5G2R7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ] }, { "name": "EIF3S6IP", "type": "synonym", "evidence": [ { "id": "A0A5G2R7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 3 subunit L", "type": "recommended", "evidence": [ { "id": "A0A5G2R7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3/entry#names_and_taxonomy" } ] }, { "name": "Eukaryotic translation initiation factor 3 subunit 6-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A5G2R7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3/entry#names_and_taxonomy" } ] }, { "name": "Eukaryotic translation initiation factor 3 subunit E-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A5G2R7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3/entry#names_and_taxonomy" } ] }, { "name": "eIF3l", "type": "synonym", "evidence": [ { "id": "A0A5G2R7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AL05", "url": "https://www.uniprot.org/uniprotkb/A0A287AL05#function" }, { "database": "HAMAP", "id": "MF_03011", "url": "https://hamap.expasy.org/signature/MF_03011" }, { "database": "UniProtKB", "id": "A0A8D1BFA5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1BFA5#function" }, { "database": "UniProtKB", "id": "A0A287BK74", "url": "https://www.uniprot.org/uniprotkb/A0A287BK74#function" }, { "database": "UniProtKB", "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3#function" }, { "database": "UniProtKB", "id": "F1SKN5", "url": "https://www.uniprot.org/uniprotkb/F1SKN5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EIF3L", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3", "locus": { "chromosome": "5", "start_pos": 9968428, "end_pos": 10000092, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000119", "url": "https://www.ensembl.org/id/ENSSSCG00000000119" } ] } } ], "crossref": [ { "id": "A0A5G2R7X3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7X3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000119", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000119", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13242", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13242", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13242:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13242:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10255", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10255", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AL05", "url": "https://www.uniprot.org/uniprotkb/A0A287AL05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AL05-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AL05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BK74", "url": "https://www.uniprot.org/uniprotkb/A0A287BK74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BK74-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BK74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1BFA5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1BFA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1BFA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1BFA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SKN5", "url": "https://www.uniprot.org/uniprotkb/F1SKN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SKN5-1", "url": "https://www.uniprot.org/uniprotkb/F1SKN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNYRPVACPAMSLTKRCMRSRTSMRTDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 466, "header": "tr|A0A5G2R7X3-1|A0A5G2R7X3_PIG Isoform 1 of Eukaryotic translation initiation factor 3 subunit L OS=Sus scrofa OX=9823 GN=EIF3L PE=1 SV=1 CANONICAL=A0A5G2R7X3-1" }, "isoforms": [ { "isoform_ac": "A0A287AL05-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3/entry#A0A287AL05-1", "sequence": { "sequence": "MPWERPKKRQKDKTKQNERNRPVAIESDIKRIYISGCLKGNGSSLVAQRVKDLMPLLWLWSLDCCGNFCMPPPLPTKGIIPNCIDFSLGGGRPCPFVTHVDLRCHIPPLGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAETIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 629, "header": "tr|A0A287AL05-1|A0A5G2R7X3_PIG Computationally mapped isoform of Eukaryotic translation initiation factor 3 subunit L OS=Sus scrofa OX=9823 GN=EIF3L PE=1 SV=1 CANONICAL=A0A5G2R7X3-1" }, "locus": { "chromosome": "5", "start_pos": 9994259, "end_pos": 9970193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036950.2", "url": "https://www.ensembl.org/id/ENSSSCT00000036950.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044686.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044686.1" } ] } }, { "isoform_ac": "A0A287BK74-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3/entry#A0A287BK74-1", "sequence": { "sequence": "VAEGPGRASGFPANSRWAGLPASRRRRGALFPLFPPGPRSAAAMSYPADDYESETAYDPYAYPGDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAETIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 607, "header": "tr|A0A287BK74-1|A0A5G2R7X3_PIG Computationally mapped isoform of Eukaryotic translation initiation factor 3 subunit L OS=Sus scrofa OX=9823 GN=EIF3L PE=1 SV=2 CANONICAL=A0A5G2R7X3-1" }, "locus": { "chromosome": "5", "start_pos": 9996122, "end_pos": 9970193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046625.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046625.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056553.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056553.2" } ] } }, { "isoform_ac": "A0A5G2R7X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3/entry#A0A5G2R7X3-1", "sequence": { "sequence": "MNYRPVACPAMSLTKRCMRSRTSMRTDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 466, "header": "tr|A0A5G2R7X3-1|A0A5G2R7X3_PIG Isoform 1 of Eukaryotic translation initiation factor 3 subunit L OS=Sus scrofa OX=9823 GN=EIF3L PE=1 SV=1 CANONICAL=A0A5G2R7X3-1" }, "locus": { "chromosome": "5", "start_pos": 9993799, "end_pos": 9970193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076216.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076216.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066706.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066706.1" } ] } }, { "isoform_ac": "A0A8D1BFA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3/entry#A0A8D1BFA5-1", "sequence": { "sequence": "MSYPADDYESETAYDPYAYPGDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAETIAPQVGNDAVFLILYKELYYRHIYAKVSFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 516, "header": "tr|A0A8D1BFA5-1|A0A5G2R7X3_PIG Computationally mapped isoform of Eukaryotic translation initiation factor 3 subunit L OS=Sus scrofa OX=9823 GN=EIF3L PE=1 SV=1 CANONICAL=A0A5G2R7X3-1" }, "locus": { "chromosome": "5", "start_pos": 9995993, "end_pos": 9970193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077783.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077783.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063735.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063735.1" } ] } }, { "isoform_ac": "F1SKN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3/entry#F1SKN5-1", "sequence": { "sequence": "MSYPADDYESETAYDPYAYPGDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAETIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 532, "header": "tr|F1SKN5-1|F1SKN5_PIG Computationally mapped isoform of Eukaryotic translation initiation factor 3 subunit L OS=Sus scrofa OX=9823 GN=EIF3L PE=1 SV=5 CANONICAL=A0A5G2R7X3-1" }, "locus": { "chromosome": "5", "start_pos": 9995993, "end_pos": 9970193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000125.5", "url": "https://www.ensembl.org/id/ENSSSCT00000000125.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000123.5", "url": "https://www.ensembl.org/id/ENSSSCP00000000123.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AL05", "url": "https://www.uniprot.org/uniprotkb/A0A287AL05" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-SSC-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ], "pmid": "" }, { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ], "pmid": "" }, { "name": "viral translational termination-reinitiation", "id": "GO:0075525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7X3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 466, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7X3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7X3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X3" }, { "id": "PS50250", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50250" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PCI", "eco_id": "ECO_0000259", "start_pos": 233, "end_pos": 439, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 456, "end_pos": 458 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9B5-1", "uniprot_ac": "A0A5G2R9B5", "uniprot_id": "A0A5G2R9B5_PIG", "mass": { "chemical_mass": 39155.0, "monoisotopic_mass": 39155.0 }, "refseq": { "ac": "NP_001231751", "name": "rRNA methyltransferase 1, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231751" }, "gene_names": [ { "name": "MRM1", "type": "recommended", "evidence": [ { "id": "A0A5G2R9B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5" } ] }, { "name": "MRM1", "type": "synonym", "evidence": [ { "id": "NP_001231751", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231751" } ] } ], "protein_names": [ { "name": "rRNA methyltransferase 1, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A5G2R9B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5/entry#names_and_taxonomy" } ] }, { "name": "16S rRNA (guanosine(1145)-2'-O)-methyltransferase", "type": "synonym", "evidence": [ { "id": "A0A5G2R9B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5/entry#names_and_taxonomy" } ] }, { "name": "16S rRNA [Gm1145] 2'-O-methyltransferase", "type": "synonym", "evidence": [ { "id": "A0A5G2R9B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial rRNA methyltransferase 1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001231751", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231751" } ] }, { "name": "rRNA methyltransferase 1, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001231751", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231751" } ] } ], "function": [ { "annotation": "S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1145 (Gm1145) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5#function" }, { "database": "UniProtKB", "id": "ARBA00055894", "url": "https://www.uniprot.org/uniprotkb/ARBA00055894#function" }, { "database": "UniProtKB", "id": "F1S1B8", "url": "https://www.uniprot.org/uniprotkb/F1S1B8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MRM1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5", "locus": { "chromosome": "12", "start_pos": 38144083, "end_pos": 38124400, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017690", "url": "https://www.ensembl.org/id/ENSSSCG00000017690" } ] } } ], "crossref": [ { "id": "A0A5G2R9B5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9B5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017690", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017690", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18105", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18105", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513493", "url": "https://www.ncbi.nlm.nih.gov/gene/100513493", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001537", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001537", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029026", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029026", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513493", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513493", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVPPYEY", "url": "https://omabrowser.org/oma/group/QVPPYEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R9B5", "url": "https://www.orthodb.org/?gene=A0A5G2R9B5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46103:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46103:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08032", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08032", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231751", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231751", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "47776", "url": "https://www.rhea-db.org/rhea/47776", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R9B5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1B8", "url": "https://www.uniprot.org/uniprotkb/F1S1B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1B8-1", "url": "https://www.uniprot.org/uniprotkb/F1S1B8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELLSAARGATWRCCGRLLTRPFSQAARRGDRPGGEELSRLLLDDLALPPRSAGGLELLFGLSPCLLALRAARRRVARLLLQAGRSGLQGERAELLRVAEARDIPVLRPRRRKLDVLCRYQVHQGVCMEVSPLRPQPWAEAGESRPGDDPQQLWLVLEGLQDPRNLGAVLRSAHFLGVEKVITSRKNSCPLTPVVSKASAGAMEVMDVFSTDDLAGFLQAKARQGWLVAGTVGCPGPEISPSSEVPITSCLDFLWDQPTLLVLGNEGSGLSREVQASCQLLLTILPGRQLPPGLESLNVSVAAGILLHSICSQRKGFPVEQKREQHLLQDPQEPWPLSEGPSLTQHPGLCSGSAKQRQDGD", "length": 361, "header": "tr|A0A5G2R9B5-1|A0A5G2R9B5_PIG Isoform 1 of rRNA methyltransferase 1, mitochondrial OS=Sus scrofa OX=9823 GN=MRM1 PE=3 SV=1 CANONICAL=A0A5G2R9B5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5/entry#A0A5G2R9B5-1", "sequence": { "sequence": "MELLSAARGATWRCCGRLLTRPFSQAARRGDRPGGEELSRLLLDDLALPPRSAGGLELLFGLSPCLLALRAARRRVARLLLQAGRSGLQGERAELLRVAEARDIPVLRPRRRKLDVLCRYQVHQGVCMEVSPLRPQPWAEAGESRPGDDPQQLWLVLEGLQDPRNLGAVLRSAHFLGVEKVITSRKNSCPLTPVVSKASAGAMEVMDVFSTDDLAGFLQAKARQGWLVAGTVGCPGPEISPSSEVPITSCLDFLWDQPTLLVLGNEGSGLSREVQASCQLLLTILPGRQLPPGLESLNVSVAAGILLHSICSQRKGFPVEQKREQHLLQDPQEPWPLSEGPSLTQHPGLCSGSAKQRQDGD", "length": 361, "header": "tr|A0A5G2R9B5-1|A0A5G2R9B5_PIG Isoform 1 of rRNA methyltransferase 1, mitochondrial OS=Sus scrofa OX=9823 GN=MRM1 PE=3 SV=1 CANONICAL=A0A5G2R9B5-1" }, "locus": { "chromosome": "12", "start_pos": 38129174, "end_pos": 38124593, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070330.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070330.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070714.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070714.1" } ] } }, { "isoform_ac": "F1S1B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5/entry#F1S1B8-1", "sequence": { "sequence": "MELLSAARGATWRCCGRLLTRPFSQAARRGDRPGGEELSRLLLDDLALPPRSAGGLELLFGLSPCLLALRAARRRVARLLLQAGRSGLQGERAELLRVAEARDIPVLRPRRRKLDVLCRYQVHQGVCMEVSPLRPQPWAEAGESRPGDDPQQLWLVLEGLQDPRNLGAVLRSAHFLGVEKVITSRKNSCPLTPVVSKASAGAMEVMDVFSTDDLAGFLQAKARQGWLVAGTVGCPGPEISPSSEVPITSCLDFLWDQPTLLVLGNEGSGLSREVQASCQLLLTILPGRQLPPGLESLNVSVAAALGGRECSPFGPSAWPDGDNEDTSAPLLRPPTPAKDGANTLSLPCTGPLGSQWLVSSSWRLT", "length": 365, "header": "tr|F1S1B8-1|A0A5G2R9B5_PIG Computationally mapped isoform of rRNA methyltransferase 1, mitochondrial OS=Sus scrofa OX=9823 GN=MRM1 PE=3 SV=2 CANONICAL=A0A5G2R9B5-1" }, "locus": { "chromosome": "12", "start_pos": 38142689, "end_pos": 38124593, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019255.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019255.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018745.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018745.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1B8", "url": "https://www.uniprot.org/uniprotkb/F1S1B8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513493", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513493", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QCQ5-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "Mrm1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRLLWTVGCFGILTARHFSPVARPGGEELSRLLLDDLPPTQRLERLFGLSPCLLALRAARRRVARLLLQAGKAGLQGERAELLRVAEARGIPVLRPRRQKLDALCGHQVHQGVCMEVSPLRPRLCDDEAAEASPGDDPQQLWLVLEGLQDPRNLGAVLRSAHFLGVDRVITSRRNSCPLTPVVSKASAGAVEVMDVFATSDLAGFLKAKAQQGWLVVGTVGCPGPEISHSTKVPITSCLEFIWDRPTLLVLGNEGSGLSQEVLASCQLLLTILPRRHLPPGLESLNVSVATGILLHSICSQKKSFPVQTEKGQLLQDT", "length": 318 }, "evidence": [ { "id": "A0A5G2R9B5", "url": "https://omabrowser.org/oma/group/A0A5G2R9B5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V1AB93-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "MRM1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERALRSLARRALGLPSTARSRCFGEGPTRDQQPSRLCTAAARGGDGARTFRGGLHAAREGWGSAGREASKGRRRPEGRALPIERTRGSEILFGVAPCSMALSQARRDLFRLFLKRSGGPQRLVTSEFVLQAAARGVPVLHVGRRELDTLCGGRVHQGVCLEATPLRFKRLEEAEEPGLGDGESPNRQLLWLALEQIQDPMNLGALLRSAYFLGVDRVVTSQRNSCPLTPTVSKASSGAMEVFDVYSTDDLRSFLKAKAAEGWEVVGTVSQSETVENVPVISCLEFRWNKPIILVIGSEGDGLSLETQLLCHQMLVIPSGRALHPGIESLNVSVATGILLHSICSQKLRNSD", "length": 352 }, "evidence": [ { "id": "A0A5G2R9B5", "url": "https://omabrowser.org/oma/group/A0A5G2R9B5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZK81-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "Mrm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLWTVGCFNRLVARHFSSVARPGERPGGEELSRLLLDDLAPAQRLERLFGVSPCLLALRAARRHVARLLLQAGKAGLQGERAELLRVAEARGIPVLRPRRQKLDALCGYQVHQGVCMEVSRLRPRPCDEAADTSSGDDPQQLWLVLEGIQDPRNLGAVMRSAYFLGVDRVITSRRNSCPLTPVVSKASAGAMEVMDVFASPDLASFLQAKAQQGWLVVGTVGCPGPEISQSSKVPVTSCLEFIWDRPTLLVLGNEGSGLSQGVFATCQLLLTILPGRHLPPGLESLNVSVATGILLHSICSQKKGFPVQERGQRLQDS", "length": 320 }, "evidence": [ { "id": "A0A5G2R9B5", "url": "https://omabrowser.org/oma/group/A0A5G2R9B5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IN84-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "MRM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLSTVRGATWGRLVTRHFSHAARHGERPGGEELSRLLLDDLVPTSRLELLFGMTPCLLALQAARRSVARLLLQAGKAGLQGKRAELLRMAEARDIPVLRPRRQKLDTMCRYQVHQGVCMEVSPLRPRPWREAGEASPGDDPQQLWLVLDGIQDPRNFGAVLRSAHFLGVDKVITSRRNSCPLTPVVSKSSAGAMEVMDVFSTDDLTGFLQTKAQQGWLVAGTVGCPSTEDPQSSEIPIMSCLEFLWERPTLLVLGNEGSGLSQEVQASCQLLLTILPRRQLPPGLESLNVSVAAGILLHSICSQRKGFPTEGERRQLLQDPQEPSARSEGLSMAQHPGLSSGPEKERQNEG", "length": 353 }, "evidence": [ { "id": "A0A5G2R9B5", "url": "https://omabrowser.org/oma/group/A0A5G2R9B5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99J25-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "Mrm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRLWTVGCFSRLIARHFSSVARRGERPGGEELSRLLLDDLAPAQRLERLFGLSPCLLALRAARRRVARLLLQAGKAGLQGERAELLRVAEARGIPVLRPRRQKLDALCGYQVHQGVCMEVSPLRPRPCDEAADTSSGDDPQQLWLVLEGLQDPRNLGAVMRSAHFLGVDRVITSQRNSCPLTPVVSKASAGAMEVMDVFATPDLPGFLQAKAQQGWLVVGTVGCPGPEISQSSKVPITSCLEFVWDRPTLLVLGSEGSGLSQEVFASCQLLLTILPRRHLPPGLESLNVSVATGILLHSICSQKKGFPVQERGQLLQDS", "length": 320 }, "evidence": [ { "id": "A0A5G2R9B5", "url": "https://omabrowser.org/oma/group/A0A5G2R9B5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "rRNA (guanine) methyltransferase activity", "id": "GO:0016435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016435", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5" } ], "pmid": "" }, { "name": "rRNA (guanosine-2'-O-)-methyltransferase activity", "id": "GO:0070039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070039", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA modification", "id": "GO:0000154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000154", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5" } ], "pmid": "" }, { "name": "rRNA methylation", "id": "GO:0031167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031167", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "47776", "name": "", "equation": "guanosine(1145) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(1145) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "47776", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47776" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9B5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 361, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9B5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9B5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B5" }, { "id": "SM00967", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00967" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNA 2-O ribose methyltransferase substrate binding", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 136, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAD8-1", "uniprot_ac": "A0A5G2RAD8", "uniprot_id": "A0A5G2RAD8_PIG", "mass": { "chemical_mass": 105026.0, "monoisotopic_mass": 105026.0 }, "refseq": {}, "gene_names": [ { "name": "CASK", "type": "recommended", "evidence": [ { "id": "A0A5G2RAD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ] } ], "protein_names": [ { "name": "Peripheral plasma membrane protein CASK", "type": "recommended", "evidence": [ { "id": "A0A5G2RAD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A5G2RAD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8/entry#names_and_taxonomy" } ] }, { "name": "Calcium/calmodulin-dependent serine protein kinase", "type": "synonym", "evidence": [ { "id": "A0A5G2RAD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CASK", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8", "locus": { "chromosome": "X", "start_pos": 37167577, "end_pos": 37536160, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012253", "url": "https://www.ensembl.org/id/ENSSSCG00000012253" } ] } } ], "crossref": [ { "id": "A0A5G2RAD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012253", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012253", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10831", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10831", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12081", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12081", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14094", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14094", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23122", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23122", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02828", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02828", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-212676", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6794361", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6794361", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZNV9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZNV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q877", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q877", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q877-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q877-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QEM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QEM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8E2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8E2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GSB2", "url": "https://www.uniprot.org/uniprotkb/K7GSB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GSB2-1", "url": "https://www.uniprot.org/uniprotkb/K7GSB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY", "length": 925, "header": "tr|A0A5G2RAD8-1|A0A5G2RAD8_PIG Isoform 1 of Peripheral plasma membrane protein CASK OS=Sus scrofa OX=9823 GN=CASK PE=1 SV=1 CANONICAL=A0A5G2RAD8-1" }, "isoforms": [ { "isoform_ac": "A0A286ZNV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8/entry#A0A286ZNV9-1", "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKVKETKKKKQKNKKTKQKKP", "length": 162, "header": "tr|A0A286ZNV9-1|A0A5G2RAD8_PIG Computationally mapped isoform of Peripheral plasma membrane protein CASK OS=Sus scrofa OX=9823 GN=CASK PE=1 SV=2 CANONICAL=A0A5G2RAD8-1" }, "locus": { "chromosome": "X", "start_pos": 37535574, "end_pos": 37341577, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049875.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049875.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033162.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033162.2" } ] } }, { "isoform_ac": "A0A5G2Q877-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8/entry#A0A5G2Q877-1", "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY", "length": 908, "header": "tr|A0A5G2Q877-1|A0A5G2RAD8_PIG Computationally mapped isoform of Peripheral plasma membrane protein CASK OS=Sus scrofa OX=9823 GN=CASK PE=1 SV=1 CANONICAL=A0A5G2RAD8-1" }, "locus": { "chromosome": "X", "start_pos": 37535574, "end_pos": 37168793, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073649.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073649.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060379.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060379.1" } ] } }, { "isoform_ac": "A0A5G2QEM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8/entry#A0A5G2QEM6-1", "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKVKHRAVQERKPVGLPPDA", "length": 161, "header": "tr|A0A5G2QEM6-1|A0A5G2RAD8_PIG Computationally mapped isoform of Peripheral plasma membrane protein CASK OS=Sus scrofa OX=9823 GN=CASK PE=1 SV=2 CANONICAL=A0A5G2RAD8-1" }, "locus": { "chromosome": "X", "start_pos": 37535574, "end_pos": 37342672, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066900.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066900.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063140.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063140.2" } ] } }, { "isoform_ac": "A0A5G2RAD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8/entry#A0A5G2RAD8-1", "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY", "length": 925, "header": "tr|A0A5G2RAD8-1|A0A5G2RAD8_PIG Isoform 1 of Peripheral plasma membrane protein CASK OS=Sus scrofa OX=9823 GN=CASK PE=1 SV=1 CANONICAL=A0A5G2RAD8-1" }, "locus": { "chromosome": "X", "start_pos": 37535574, "end_pos": 37168793, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089042.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089042.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071095.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071095.1" } ] } }, { "isoform_ac": "A0A5G2RKB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8/entry#A0A5G2RKB8-1", "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPEELPDFSEDPTSSGAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCEIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY", "length": 884, "header": "tr|A0A5G2RKB8-1|A0A5G2RAD8_PIG Computationally mapped isoform of Peripheral plasma membrane protein CASK OS=Sus scrofa OX=9823 GN=CASK PE=1 SV=2 CANONICAL=A0A5G2RAD8-1" }, "locus": { "chromosome": "X", "start_pos": 37535574, "end_pos": 37168793, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083056.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083056.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072507.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072507.2" } ] } }, { "isoform_ac": "A0A8W4F8E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8/entry#A0A8W4F8E2-1", "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPEELPDFSEDPTSSGAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQGLEKSSGQGWLEAKSQSWSWSSTSSPWVPHWSSPERRFLLALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY", "length": 954, "header": "tr|A0A8W4F8E2-1|A0A5G2RAD8_PIG Computationally mapped isoform of Peripheral plasma membrane protein CASK OS=Sus scrofa OX=9823 GN=CASK PE=1 SV=1 CANONICAL=A0A5G2RAD8-1" }, "locus": { "chromosome": "X", "start_pos": 37535574, "end_pos": 37168793, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105761.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105761.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075535.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075535.1" } ] } }, { "isoform_ac": "K7GSB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8/entry#K7GSB2-1", "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPEELPDFSEDPTSSGAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCEDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY", "length": 896, "header": "tr|K7GSB2-1|A0A5G2RAD8_PIG Computationally mapped isoform of Peripheral plasma membrane protein CASK OS=Sus scrofa OX=9823 GN=CASK PE=1 SV=3 CANONICAL=A0A5G2RAD8-1" }, "locus": { "chromosome": "X", "start_pos": 37535574, "end_pos": 37168793, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035253.3", "url": "https://www.ensembl.org/id/ENSSSCT00000035253.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030793.3", "url": "https://www.ensembl.org/id/ENSSSCP00000030793.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 862, "start_aa": "Thr", "end_pos": 862, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr862", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2Q877", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q877" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-212676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212676", "resource": "Reactome", "description": "Dopamine Neurotransmitter Release Cycle" }, { "id": "R-SSC-6794361", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6794361", "resource": "Reactome", "description": "Neurexins and neuroligins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "neurexin family protein binding", "id": "GO:0042043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042043", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 14, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "nuclear lamina", "id": "GO:0005652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005652", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "negative regulation of cell-matrix adhesion", "id": "GO:0001953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001953", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "regulation of neurotransmitter secretion", "id": "GO:0046928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046928", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "negative regulation of wound healing", "id": "GO:0061045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061045", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "negative regulation of keratinocyte proliferation", "id": "GO:0010839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010839", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "negative regulation of cellular response to growth factor stimulus", "id": "GO:0090288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090288", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle exocytosis", "id": "GO:2000300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000300", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-SSC-380574", "name": "Dopamine synaptic vesicle docking and priming", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane, clathrin-sculpted monoamine transport vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-380574", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380574" } ] }, { "id": "R-SSC-5336443", "name": "LIN7, CASK and APBA1 bind", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5336443", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5336443" } ] }, { "id": "R-SSC-6797553", "name": "Protein 4.1 binds CASK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6797553", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6797553" } ] }, { "id": "R-SSC-6797568", "name": "NRXNs bind CASK:Protein 4.1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6797568", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6797568" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAD8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 925, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAD8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAD8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" }, { "id": "PS50052", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50052" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate kinase-like", "eco_id": "ECO_0000259", "start_pos": 738, "end_pos": 910, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RAD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" }, { "id": "PS51022", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L27", "eco_id": "ECO_0000259", "start_pos": 342, "end_pos": 397, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RAD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 489, "end_pos": 570, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RAD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 276, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RAD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD8" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 611, "end_pos": 681, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 862 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 483, "end_pos": 485 }, { "start_pos": 545, "end_pos": 547 }, { "start_pos": 597, "end_pos": 599 }, { "start_pos": 665, "end_pos": 667 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAB6-1", "uniprot_ac": "A0A5G2RAB6", "uniprot_id": "A0A5G2RAB6_PIG", "mass": { "chemical_mass": 206308.0, "monoisotopic_mass": 206308.0 }, "refseq": { "ac": "XP_020920664", "name": "proprotein convertase subtilisin/kexin type 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920664" }, "gene_names": [ { "name": "PCSK5", "type": "recommended", "evidence": [ { "id": "A0A5G2RAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ] }, { "name": "PCSK5", "type": "synonym", "evidence": [ { "id": "XP_020920664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920664" } ] } ], "protein_names": [ { "name": "Proprotein convertase subtilisin/kexin type 5", "type": "recommended", "evidence": [ { "id": "A0A5G2RAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6/entry#names_and_taxonomy" } ] }, { "name": "Proprotein convertase 5", "type": "synonym", "evidence": [ { "id": "A0A5G2RAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6/entry#names_and_taxonomy" } ] }, { "name": "Proprotein convertase 6", "type": "synonym", "evidence": [ { "id": "A0A5G2RAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6/entry#names_and_taxonomy" } ] }, { "name": "Subtilisin/kexin-like protease PC5", "type": "synonym", "evidence": [ { "id": "A0A5G2RAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6/entry#names_and_taxonomy" } ] }, { "name": "proprotein convertase subtilisin/kexin type 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020920664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920664" } ] } ], "function": [ { "annotation": "Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive and regulated secretory pathways. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins. May be responsible for the maturation of gastrointestinal peptides. May be involved in the cellular proliferation of adrenal cortex via the activation of growth factors.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1ZHZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1ZHZ0#function" }, { "database": "UniProtKB", "id": "ARBA00053092", "url": "https://www.uniprot.org/uniprotkb/ARBA00053092#function" }, { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6#function" }, { "database": "UniProtKB", "id": "A0A480HFV4", "url": "https://www.uniprot.org/uniprotkb/A0A480HFV4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PCSK5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6", "locus": { "chromosome": "1", "start_pos": 229308906, "end_pos": 228854595, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000023520", "url": "https://www.ensembl.org/id/ENSSSCG00000023520" } ] } } ], "crossref": [ { "id": "ENSSSCG00000023520", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000023520", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00064", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00064", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519237", "url": "https://www.ncbi.nlm.nih.gov/gene/100519237", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519237", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519237", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICATCEG", "url": "https://omabrowser.org/oma/group/ICATCEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8D1ZHZ0", "url": "https://www.orthodb.org/?gene=A0A8D1ZHZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42884:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42884:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00082", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00082", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01483", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01483", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14843", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-167060", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-167060", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8963889", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8963889", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020920664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920664", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A480HFV4", "url": "https://www.uniprot.org/uniprotkb/A0A480HFV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480HFV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A480HFV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1ZHZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1ZHZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1ZHZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1ZHZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCK6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L731", "url": "https://www.uniprot.org/uniprotkb/I3L731", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L731-1", "url": "https://www.uniprot.org/uniprotkb/I3L731-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGWGSRCCCPGRLDLLCVLALLGGCLLPVCRTRVYTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDFSRAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNARIGGVRMLDGDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWILEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERVRYSRVEDPTDDYGTEDYAGPCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHYHADKKRCRKCAPNCETCFGSHGDQCLSCKYGYFLNEETNSCVTHCPDGSYQDPKKNLCRKCNENCKTCTESDNCTECREGLSLQGSRCSVACDDGRYFNGQDCQPCHRFCATCAGAGADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENGFKSCKKCDASCLTCNGPGFKNCTSCPSGYLLDLGMCQMGAICKDGEYIDEHGRCQICEASCAKCQGPTQDDCTGCPVTRILDDGHCVLNCPSGKFALKNRCHLCHSTCRECQGDEPSNCTSCGVDKHGQERFLYWGECRERCPRGHYADEGHTCQPCPDNCELCHSPHFCIRCVHGYFMVPANHTCQKLECRQGEVQDPDYEECMPCEEGCLGCSSDDPGTCTSCATGYYMFKHHCYKTCPEKTYREASGCKACETNCGSCDQNECYWCEEGFFLLGGSCVKNCGPGFYGNPEMGECEPCHQACETCTGLGHNQCSSCRGGLQLLHGTCVRPARTQVEGSFWNDLVRRYQPCHSSCRTCHGSATQCTSCPKGAYLLAQTCVLSCPQGTWPSARSGSCENCTEDCASCSDANLCKKCRTQPDHPLFLHEGRCFTKCPEGFYVEDGTCERCSSSCRTCEGNATNCHSCEGGLVLDQGMCRKTCPERHVAVEGVCKHCPEMCQDCIHETTCKECMPESFLYNDACHQSCPSHFYADARLCVPCHEDCLECSGPSADDCDLCAEASLILYNGQCLEECPEGTYFERATKVCKDCPKSCRSCSSLGICTTCREGLRVNNHGGCVPHTECATVEYWDEEALACKACHAKCFRCTGPSEDQCLTCLRDSLLLNTTCVKDCPEGHYADEDSHRCAPCHSSCRTCEGRHSMQCLSCQPGWFQLGKECLLQCREGFYAENSTQRCERCNRSCKACRGPRPTDCLSCDPFFFLLRSKGQCHSTCPEHYYAEQSTKTCERCHPTCHKCKGQTALDCLSCVWSYHLVGGICTSDCLVGEYRVGEGEKFNCEKCHESCIECKGPGTKNCTVCPANLLLHMDDGRCLACCNASDPADAQECCDCQDTTDECILRASEAKPAGERSKTALFITSSIMLVLLLGAAVIVWRKSQGRVKPAEKAGYLKLADPSKSYSSYKSSHLESTSFEEDQVIEYRDRDYDEDEDDDIVYMGQDGTVYRKFKYGLLDDEDEDELEYDDESYSYQ", "length": 1859, "header": "tr|A0A5G2RAB6-1|A0A5G2RAB6_PIG Isoform 1 of Proprotein convertase subtilisin/kexin type 5 OS=Sus scrofa OX=9823 GN=PCSK5 PE=3 SV=1 CANONICAL=A0A5G2RAB6-1" }, "isoforms": [ { "isoform_ac": "A0A480HFV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6/entry#A0A480HFV4-1", "sequence": { "sequence": "MGWGSRCCCPGRLDLLCVLALLGGCLLPVCRTRVYTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDFSRAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNARIGGVRMLDGDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWILEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERVRYSRVEDPTDDYGTEDYAGPCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHYHADKKRCRKCAPNCETCFGSHGDQCLSCKYGYFLNEETNSCVTHCPDGSYQDPKKNLCRKCNENCKTCTESDNCTECREGLSLQGSRCSVACDDGRYFNGQDCQPCHRFCATCAGAGADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENGFKSCKKCDASCLTCNGPGFKNCTSCPSGYLLDLGMCQMGAICKDATEESWAEGGFCMLVKKNNLCQRKVLQQLCCKTCTFQG", "length": 913, "header": "tr|A0A480HFV4-1|A0A480HFV4_PIG Computationally mapped isoform of Proprotein convertase subtilisin/kexin type 5 OS=Sus scrofa OX=9823 GN=PCSK5 PE=3 SV=1 CANONICAL=A0A5G2RAB6-1" }, "locus": { "chromosome": "1", "start_pos": 229158371, "end_pos": 228855114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080178.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080178.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066032.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066032.1" } ] } }, { "isoform_ac": "A0A5G2RAB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6/entry#A0A5G2RAB6-1", "sequence": { "sequence": "MGWGSRCCCPGRLDLLCVLALLGGCLLPVCRTRVYTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDFSRAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNARIGGVRMLDGDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWILEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERVRYSRVEDPTDDYGTEDYAGPCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHYHADKKRCRKCAPNCETCFGSHGDQCLSCKYGYFLNEETNSCVTHCPDGSYQDPKKNLCRKCNENCKTCTESDNCTECREGLSLQGSRCSVACDDGRYFNGQDCQPCHRFCATCAGAGADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENGFKSCKKCDASCLTCNGPGFKNCTSCPSGYLLDLGMCQMGAICKDGEYIDEHGRCQICEASCAKCQGPTQDDCTGCPVTRILDDGHCVLNCPSGKFALKNRCHLCHSTCRECQGDEPSNCTSCGVDKHGQERFLYWGECRERCPRGHYADEGHTCQPCPDNCELCHSPHFCIRCVHGYFMVPANHTCQKLECRQGEVQDPDYEECMPCEEGCLGCSSDDPGTCTSCATGYYMFKHHCYKTCPEKTYREASGCKACETNCGSCDQNECYWCEEGFFLLGGSCVKNCGPGFYGNPEMGECEPCHQACETCTGLGHNQCSSCRGGLQLLHGTCVRPARTQVEGSFWNDLVRRYQPCHSSCRTCHGSATQCTSCPKGAYLLAQTCVLSCPQGTWPSARSGSCENCTEDCASCSDANLCKKCRTQPDHPLFLHEGRCFTKCPEGFYVEDGTCERCSSSCRTCEGNATNCHSCEGGLVLDQGMCRKTCPERHVAVEGVCKHCPEMCQDCIHETTCKECMPESFLYNDACHQSCPSHFYADARLCVPCHEDCLECSGPSADDCDLCAEASLILYNGQCLEECPEGTYFERATKVCKDCPKSCRSCSSLGICTTCREGLRVNNHGGCVPHTECATVEYWDEEALACKACHAKCFRCTGPSEDQCLTCLRDSLLLNTTCVKDCPEGHYADEDSHRCAPCHSSCRTCEGRHSMQCLSCQPGWFQLGKECLLQCREGFYAENSTQRCERCNRSCKACRGPRPTDCLSCDPFFFLLRSKGQCHSTCPEHYYAEQSTKTCERCHPTCHKCKGQTALDCLSCVWSYHLVGGICTSDCLVGEYRVGEGEKFNCEKCHESCIECKGPGTKNCTVCPANLLLHMDDGRCLACCNASDPADAQECCDCQDTTDECILRASEAKPAGERSKTALFITSSIMLVLLLGAAVIVWRKSQGRVKPAEKAGYLKLADPSKSYSSYKSSHLESTSFEEDQVIEYRDRDYDEDEDDDIVYMGQDGTVYRKFKYGLLDDEDEDELEYDDESYSYQ", "length": 1859, "header": "tr|A0A5G2RAB6-1|A0A5G2RAB6_PIG Isoform 1 of Proprotein convertase subtilisin/kexin type 5 OS=Sus scrofa OX=9823 GN=PCSK5 PE=3 SV=1 CANONICAL=A0A5G2RAB6-1" }, "locus": { "chromosome": "1", "start_pos": 229306705, "end_pos": 228855114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087592.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087592.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073264.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073264.1" } ] } }, { "isoform_ac": "A0A8D1ZHZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6/entry#A0A8D1ZHZ0-1", "sequence": { "sequence": "MGWGSRCCCPGRLDLLCVLALLGGCLLPVCRTRVYTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDFSRAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNARIGGVRMLDGDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWILEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERVRYSRVEDPTDDYGTEDYAGPCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHYHADKKRCRKCAPNCETCFGSHGDQCLSCKYGYFLNEETNSCVTHCPDGSYQDPKKNLCRKCNENCKTCTESDNCTECREGLSLQGSRCSVACDDGRYFNGQDCQPCHRFCATCAGAGADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENGFKSCKKCDASCLTCNGPGFKNCTSCPSGYLLDLGMCQMGAICKDGEYIDEHGRCQICEASCAKCQGPTQDDCTGCPVTRILDDGHCVLNCPSGKFALKNRCHLCHSTCRECQGDEPSNCTSCGVDKHGQERFLYWGECRERCPRGHYADEGHTCQPCPDNCELCHSPHFCIRCVHGYFMVPANHTCQKLECRQGEVQDPDYEECMPCEEGCLGCSSDDPGTCTSCATGYYMFKHHCYKTCPEKTYREASGCKACETNCGSCDQNECYWCEEGFFLLGGSCVKNCGPGFYGNPEMGECEPCHQACETCTGLGHNQCSSCRGGLQLLHGTCVRPARTQVEGSFWNETVPSASPSSMKSLLQERRRWKFQIKRDLVRRYQPCHSSCRTCHGSATQCTSCPKGAYLLAQTCVLSCPQGTWPSARSGSCENCTEDCASCSDANLCKKCRTQPDHPLFLHEGRCFTKCPEGFYVEDGTCERCSSSCRTCEGNATNCHSCEGGLVLDQGMCRKTCPERHVAVEGVCKHCPEMCQDCIHETTCKECMPESFLYNDACHQSCPSHFYADARLCVPCHEDCLECSGPSADDCDLCAEASLILYNGQCLEECPEGTYFERATKVCKDCPKSCRSCSSLGICTTCREGLRVNNHGGCVPHTECATVEYWDEEALACKACHAKCFRCTGPSEDQCLTCLRDSLLLNTTCVKDCPEGHYADEDSHRCAPCHSSCRTCEGRHSMQCLSCQPGWFQLGKECLLQCREGFYAENSTQRCERCNRSCKACRGPRPTDCLSCDPFFFLLRSKGQCHSTCPEHYYAEQSTKTCERCHPTCHKCKGQTALDCLSCVWSYHLVGGICTSDCLVGEYRVGEGEKFNCEKCHESCIECKGPGTKNCTVCPANLLLHMDDGRCLACCNASDPADAQECCDCQDTTDECILRASEAKPAGERSKTALFITSSIMLVLLLGAAVIVWRKSQGRVKPAEKAGYLKLADPSKSYSSYKSSHLESTSFEEDQVIEYRDRDYDEDEDDDIVYMGQDGTVYRKFKYGLLDDEDEDELEYDDESYSYQ", "length": 1886, "header": "tr|A0A8D1ZHZ0-1|A0A5G2RAB6_PIG Computationally mapped isoform of Proprotein convertase subtilisin/kexin type 5 OS=Sus scrofa OX=9823 GN=PCSK5 PE=3 SV=1 CANONICAL=A0A5G2RAB6-1" }, "locus": { "chromosome": "1", "start_pos": 229306705, "end_pos": 228855114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046278.2", "url": "https://www.ensembl.org/id/ENSSSCT00000046278.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057080.1", "url": "https://www.ensembl.org/id/ENSSSCP00000057080.1" } ] } }, { "isoform_ac": "A0A8W4FCK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6/entry#A0A8W4FCK6-1", "sequence": { "sequence": "MGWGSRCCCPGRLDLLCVLALLGGCLLPVCRTRVYTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDFSRAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNARIGGVRMLDGDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWILEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERVRYSRVEDPTDDYGTEDYAGELASNWRQTEDRKFMHHSSIQ", "length": 655, "header": "tr|A0A8W4FCK6-1|A0A5G2RAB6_PIG Computationally mapped isoform of Proprotein convertase subtilisin/kexin type 5 OS=Sus scrofa OX=9823 GN=PCSK5 PE=3 SV=1 CANONICAL=A0A5G2RAB6-1" }, "locus": { "chromosome": "1", "start_pos": 229140834, "end_pos": 228855114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097162.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097162.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077133.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077133.1" } ] } }, { "isoform_ac": "I3L731-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6/entry#I3L731-1", "sequence": { "sequence": "MGWGSRCCCPGRLDLLCVLALLGGCLLPVCRTRVYTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDFSRAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNARIGGVRMLDGDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWILEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERVRYSRVEDPTDDYGTEDYAGPCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHYHADKKRCRKCAPNCETCFGSHGDQCLSCKYGYFLNEETNSCVTHCGSRCSVACDDGRYFNGQDCQPCHRFCATCAGAGADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENGFKSCKKCDASCLTCNGPGFKNCTSCPSGYLLDLGMCQMGAICKDATEESWAEGGFCMLVKKNNLCQRKVLQQLCCKTCTFQG", "length": 874, "header": "tr|I3L731-1|A0A5G2RAB6_PIG Computationally mapped isoform of Proprotein convertase subtilisin/kexin type 5 OS=Sus scrofa OX=9823 GN=PCSK5 PE=3 SV=3 CANONICAL=A0A5G2RAB6-1" }, "locus": { "chromosome": "1", "start_pos": 229158371, "end_pos": 228855114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024731.3", "url": "https://www.ensembl.org/id/ENSSSCT00000024731.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019835.3", "url": "https://www.ensembl.org/id/ENSSSCP00000019835.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3L731", "url": "https://www.uniprot.org/uniprotkb/I3L731" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519237", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519237", "resource": "KEGG Pathway" }, { "id": "R-SSC-167060", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-167060", "resource": "Reactome", "description": "NGF processing" }, { "id": "R-SSC-8963889", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8963889", "resource": "Reactome", "description": "Assembly of active LPL and LIPC lipase complexes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "peptide binding", "id": "GO:0042277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042277", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 14, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "female pregnancy", "id": "GO:0007565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007565", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "viral life cycle", "id": "GO:0019058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019058", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "peptide hormone processing", "id": "GO:0016486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016486", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "embryonic digestive tract development", "id": "GO:0048566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048566", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "embryo implantation", "id": "GO:0007566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007566", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "limb morphogenesis", "id": "GO:0035108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035108", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "respiratory tube development", "id": "GO:0030323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030323", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "peptide biosynthetic process", "id": "GO:0043043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043043", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "embryonic skeletal system development", "id": "GO:0048706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048706", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "cytokine precursor processing", "id": "GO:0140447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140447", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1014, "end_pos": 1016, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1230, "end_pos": 1232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1290, "end_pos": 1292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1497, "end_pos": 1499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1561, "end_pos": 1563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1570, "end_pos": 1572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1685, "end_pos": 1687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1707, "end_pos": 1709, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 802, "end_pos": 804, "annotation": "n_glycosylation_sequon" }, { "start_pos": 852, "end_pos": 854, "annotation": "n_glycosylation_sequon" }, { "start_pos": 949, "end_pos": 951, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAB6" }, { "id": "PS51829", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51829" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "P/Homo B", "eco_id": "ECO_0000259", "start_pos": 461, "end_pos": 601, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1014, "end_pos": 1016 }, { "start_pos": 1230, "end_pos": 1232 }, { "start_pos": 1290, "end_pos": 1292 }, { "start_pos": 1497, "end_pos": 1499 }, { "start_pos": 1561, "end_pos": 1563 }, { "start_pos": 1570, "end_pos": 1572 }, { "start_pos": 1685, "end_pos": 1687 }, { "start_pos": 1707, "end_pos": 1709 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 665, "end_pos": 667 }, { "start_pos": 752, "end_pos": 754 }, { "start_pos": 802, "end_pos": 804 }, { "start_pos": 852, "end_pos": 854 }, { "start_pos": 949, "end_pos": 951 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8V7-1", "uniprot_ac": "A0A5G2R8V7", "uniprot_id": "A0A5G2R8V7_PIG", "mass": { "chemical_mass": 130225.0, "monoisotopic_mass": 130225.0 }, "refseq": {}, "gene_names": [ { "name": "LTBP3", "type": "recommended", "evidence": [ { "id": "A0A5G2R8V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" } ] } ], "protein_names": [ { "name": "Latent-transforming growth factor beta-binding protein 3", "type": "recommended", "evidence": [ { "id": "A0A5G2R8V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7#function" }, { "database": "UniProtKB", "id": "ARBA00057882", "url": "https://www.uniprot.org/uniprotkb/ARBA00057882#function" }, { "database": "UniProtKB", "id": "F1RRJ9", "url": "https://www.uniprot.org/uniprotkb/F1RRJ9#function" }, { "database": "UniProtKB", "id": "A0A5G2Q6L4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6L4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LTBP3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7", "locus": { "chromosome": "2", "start_pos": 6720153, "end_pos": 6701510, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012985", "url": "https://www.ensembl.org/id/ENSSSCG00000012985" } ] } } ], "crossref": [ { "id": "A0A5G2R8V7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8V7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012985", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012985", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100517877", "url": "https://www.ncbi.nlm.nih.gov/gene/100517877", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517877", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517877", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RRJ9", "url": "https://www.orthodb.org/?gene=F1RRJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24034:SF209", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24034:SF209", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24034:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24034:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00683", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00683", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2129379", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2129379", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2173789", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2173789", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2Q6L4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q6L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRJ9", "url": "https://www.uniprot.org/uniprotkb/F1RRJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRJ9-1", "url": "https://www.uniprot.org/uniprotkb/F1RRJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLGRAGSLSTGALPPLAPDGESVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIEGPNAEGPAPSQHLLPHPKPQHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPPEDTEEERGVSTDSPVVEEHSAQQSHPTVTTSPARPYPELISRPSPPRFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGAGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECSKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDSKCENKPGSFKCIACPPGYRSQGGGACRDVNECAEGNPCSPGWCENLPGSFRCTCAQGYAPSPDGRSCLDVDECEAGDVCDNGICNNTPGSFQCQCLSGYHLSRDRSRCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCICDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPTACRHGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPADRAPERRDVCWSQRGEDGMCAVPVSGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSQCPTSQSESNSFWDTSPLLLGKPPREEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRRR", "length": 1211, "header": "tr|A0A5G2R8V7-1|A0A5G2R8V7_PIG Isoform 1 of Latent-transforming growth factor beta-binding protein 3 OS=Sus scrofa OX=9823 GN=LTBP3 PE=3 SV=2 CANONICAL=A0A5G2R8V7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2Q6L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7/entry#A0A5G2Q6L4-1", "sequence": { "sequence": "MPGPRGAAGGLAPEMRGAGAGAGAAGLLALLLPLLLGPGGGAEGGPAGERSAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLGRAGSLSTGALPPLAPDGESVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIEGPNAEGPAPSQHLLPHPKPQHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPPEDTEEERGVSTDSPVVEEHSAQQSHPTVTTSPARPYPELISRPSPPRFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGAGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECSKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDSKCENKPGSFKCIACPPGYRSQGGGACRDVNECAEGNPCSPGWCENLPGSFRCTCAQGYAPSPDGRSCLDVDECEAGDVCDNGICNNTPGSFQCQCLSGYHLSRDRSRCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCICDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDRAPERRDVCWSQRGEDGMCAVPVSGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSQCPTSQSESNSFWDTSPLLLGKPPREEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRRR", "length": 1254, "header": "tr|A0A5G2Q6L4-1|A0A5G2Q6L4_PIG Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 3 OS=Sus scrofa OX=9823 GN=LTBP3 PE=3 SV=1 CANONICAL=A0A5G2R8V7-1" }, "locus": { "chromosome": "2", "start_pos": 6719681, "end_pos": 6701983, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084819.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084819.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059633.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059633.1" } ] } }, { "isoform_ac": "A0A5G2R8V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7/entry#A0A5G2R8V7-1", "sequence": { "sequence": "MTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLGRAGSLSTGALPPLAPDGESVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIEGPNAEGPAPSQHLLPHPKPQHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPPEDTEEERGVSTDSPVVEEHSAQQSHPTVTTSPARPYPELISRPSPPRFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGAGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECSKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDSKCENKPGSFKCIACPPGYRSQGGGACRDVNECAEGNPCSPGWCENLPGSFRCTCAQGYAPSPDGRSCLDVDECEAGDVCDNGICNNTPGSFQCQCLSGYHLSRDRSRCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCICDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPTACRHGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPADRAPERRDVCWSQRGEDGMCAVPVSGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSQCPTSQSESNSFWDTSPLLLGKPPREEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRRR", "length": 1211, "header": "tr|A0A5G2R8V7-1|A0A5G2R8V7_PIG Isoform 1 of Latent-transforming growth factor beta-binding protein 3 OS=Sus scrofa OX=9823 GN=LTBP3 PE=3 SV=2 CANONICAL=A0A5G2R8V7-1" }, "locus": { "chromosome": "2", "start_pos": 6719681, "end_pos": 6702253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076710.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076710.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073516.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073516.2" } ] } }, { "isoform_ac": "F1RRJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7/entry#F1RRJ9-1", "sequence": { "sequence": "MPGPRGAAGGLAPEMRGAGAGAGAAGLLALLLPLLLGPGGGAEGGPAGERSAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLGRAGSLSTGALPPLAPDGESVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIEGPNAEGPAPSQHLLPHPKPQHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPPEDTEEERGVSTDSPVVEEHSAQQSHPTVTTSPARPYPELISRPSPPRFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGAGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECSKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDSKCENKPGSFKCIACPPGYRSQGGGACRDVNECAEGNPCSPGWCENLPGSFRCTCAQGYAPSPDGRSCLDVDECEAGDVCDNGICNNTPGSFQCQCLSGYHLSRDRSRCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCICDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPTACRHGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPADRAPERRDVCWSQRGEDGMCAVPVSGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSQCPTSQSESNSFWDTSPLLLGKPPREEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRRR", "length": 1301, "header": "tr|F1RRJ9-1|A0A5G2R8V7_PIG Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 3 OS=Sus scrofa OX=9823 GN=LTBP3 PE=3 SV=3 CANONICAL=A0A5G2R8V7-1" }, "locus": { "chromosome": "2", "start_pos": 6719681, "end_pos": 6701983, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014195.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014195.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013809.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013809.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RRJ9", "url": "https://www.uniprot.org/uniprotkb/F1RRJ9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517877", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517877", "resource": "KEGG Pathway" }, { "id": "R-SSC-2129379", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2129379", "resource": "Reactome", "description": "Molecules associated with elastic fibres" }, { "id": "R-SSC-2173789", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2173789", "resource": "Reactome", "description": "TGF-beta receptor signaling activates SMADs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" } ], "pmid": "" }, { "name": "transforming growth factor beta binding", "id": "GO:0050431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050431", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" } ], "pmid": "" }, { "name": "regulation of cell differentiation", "id": "GO:0045595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045595", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" } ], "pmid": "" }, { "name": "positive regulation of mesenchymal stem cell proliferation", "id": "GO:1902462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902462", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" } ], "pmid": "" }, { "name": "positive regulation of mesenchymal stem cell differentiation", "id": "GO:2000741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000741", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1183, "end_pos": 1185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 753, "end_pos": 755, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8V7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1211, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8V7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8V7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 52, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R8V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8V7" }, { "id": "PS51364", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51364" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TB", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 231, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1183, "end_pos": 1185 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 709, "end_pos": 711 }, { "start_pos": 753, "end_pos": 755 }, { "start_pos": 844, "end_pos": 846 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAQ9-1", "uniprot_ac": "A0A5G2RAQ9", "uniprot_id": "A0A5G2RAQ9_PIG", "mass": { "chemical_mass": 44643.0, "monoisotopic_mass": 44643.0 }, "refseq": {}, "gene_names": [ { "name": "OLA1", "type": "recommended", "evidence": [ { "id": "A0A5G2RAQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" } ] } ], "protein_names": [ { "name": "Obg-like ATPase 1", "type": "recommended", "evidence": [ { "id": "A0A5G2RAQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FBC7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBC7#function" }, { "database": "HAMAP", "id": "MF_03167", "url": "https://hamap.expasy.org/signature/MF_03167" }, { "database": "UniProtKB", "id": "A0A5G2RH83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH83#function" }, { "database": "UniProtKB", "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9#function" }, { "database": "UniProtKB", "id": "A0A5G2RHM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHM3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OLA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9", "locus": { "chromosome": "15", "start_pos": 80078924, "end_pos": 80253741, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015963", "url": "https://www.ensembl.org/id/ENSSSCG00000015963" } ] } } ], "crossref": [ { "id": "A0A5G2RAQ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015963", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015963", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01900", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01900", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04867", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04867", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VLRCFDN", "url": "https://omabrowser.org/oma/group/VLRCFDN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23305", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23305", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23305:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23305:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RH83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RH83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RHM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RHM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBC7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S062", "url": "https://www.uniprot.org/uniprotkb/F1S062", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S062-1", "url": "https://www.uniprot.org/uniprotkb/F1S062-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPKKGGDAIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKEEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQPKKK", "length": 395, "header": "tr|A0A5G2RAQ9-1|A0A5G2RAQ9_PIG Isoform 1 of Obg-like ATPase 1 OS=Sus scrofa OX=9823 GN=OLA1 PE=1 SV=2 CANONICAL=A0A5G2RAQ9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9/entry#A0A5G2RAQ9-1", "sequence": { "sequence": "MPPKKGGDAIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKEEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQPKKK", "length": 395, "header": "tr|A0A5G2RAQ9-1|A0A5G2RAQ9_PIG Isoform 1 of Obg-like ATPase 1 OS=Sus scrofa OX=9823 GN=OLA1 PE=1 SV=2 CANONICAL=A0A5G2RAQ9-1" }, "locus": { "chromosome": "15", "start_pos": 80252347, "end_pos": 80081985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091531.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091531.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074415.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074415.2" } ] } }, { "isoform_ac": "A0A5G2RH83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9/entry#A0A5G2RH83-1", "sequence": { "sequence": "MSCTFSAKGGRDLFERPYMPPKKGGDAIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKEEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQPKKK", "length": 413, "header": "tr|A0A5G2RH83-1|A0A5G2RAQ9_PIG Computationally mapped isoform of Obg-like ATPase 1 OS=Sus scrofa OX=9823 GN=OLA1 PE=1 SV=1 CANONICAL=A0A5G2RAQ9-1" }, "locus": { "chromosome": "15", "start_pos": 80252917, "end_pos": 80081985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085276.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085276.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070671.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070671.1" } ] } }, { "isoform_ac": "A0A5G2RHM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9/entry#A0A5G2RHM3-1", "sequence": { "sequence": "MSCTFSAKGGRDLFERPWMPPKKGGDAIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKEEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQPKKK", "length": 413, "header": "tr|A0A5G2RHM3-1|A0A5G2RHM3_PIG Computationally mapped isoform of Obg-like ATPase 1 OS=Sus scrofa OX=9823 GN=OLA1 PE=1 SV=2 CANONICAL=A0A5G2RAQ9-1" }, "locus": { "chromosome": "15", "start_pos": 80252917, "end_pos": 80081985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072133.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072133.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070881.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070881.2" } ] } }, { "isoform_ac": "A0A8W4FBC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9/entry#A0A8W4FBC7-1", "sequence": { "sequence": "MPPKKGGDAIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKEEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQPKKK", "length": 385, "header": "tr|A0A8W4FBC7-1|A0A5G2RAQ9_PIG Computationally mapped isoform of Obg-like ATPase 1 OS=Sus scrofa OX=9823 GN=OLA1 PE=1 SV=1 CANONICAL=A0A5G2RAQ9-1" }, "locus": { "chromosome": "15", "start_pos": 80252347, "end_pos": 80081985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097341.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097341.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076572.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076572.1" } ] } }, { "isoform_ac": "F1S062-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9/entry#F1S062-1", "sequence": { "sequence": "MPPKKGGDAIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLLESTDNKAEIISLKMEILSSSNLIHLNNRRRNKF", "length": 277, "header": "tr|F1S062-1|A0A5G2RAQ9_PIG Computationally mapped isoform of Obg-like ATPase 1 OS=Sus scrofa OX=9823 GN=OLA1 PE=1 SV=4 CANONICAL=A0A5G2RAQ9-1" }, "locus": { "chromosome": "15", "start_pos": 80252347, "end_pos": 80081978, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017382.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017382.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016917.4", "url": "https://www.ensembl.org/id/ENSSSCP00000016917.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FBC7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBC7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LGT8-1", "protein_name": "Obg-like ATPase 1", "gene_name": "Ola1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPPKKGGDGIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKEEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQPKKK", "length": 396 }, "evidence": [ { "id": "A0A5G2RAQ9", "url": "https://omabrowser.org/oma/group/A0A5G2RAQ9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0JPJ7-1", "protein_name": "Obg-like ATPase 1", "gene_name": "Ola1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPKKGGDGLKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQCHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLLLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKSDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYDDFKDEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQSKKK", "length": 396 }, "evidence": [ { "id": "A0A5G2RAQ9", "url": "https://omabrowser.org/oma/group/A0A5G2RAQ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38219-1", "protein_name": "Obg-like ATPase 1", "gene_name": "OLA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPPKKQVEEKKVLLGRPGNNLKAGIVGLANVGKSTFFQAITRCPLGNPANYPFATIDPEEARVIVPSPRFDKLCEIYKKTASEVPAHLTVYDIAGLTKGASAGEGLGNAFLSHIRSVDSIYQVVRCFDDAEIIHVEGDVDPVRDLEIINQELRLKDIEFAQKALEGAEKIAKRGGQSLEVKQKKEEMDLITKIIKLLESGQRVANHSWTSKEVEIINSMFLLTAKPCIYLINLSERDYIRKKNKHLLRIKEWVDKYSPGDLIIPFSVSLEERLSHMSPEDAEEELKKLQTISALPKIITTMRQKLDLISFFTCGPDEVREWTIRRGTKAPQAAGVIHNDLMNTFILAQVMKCEDVFEYKDDSAIKAAGKLMQKGKDYVVEDGDIIYFRAGAGKN", "length": 394 }, "evidence": [ { "id": "A0A5G2RAQ9", "url": "https://omabrowser.org/oma/group/A0A5G2RAQ9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2HJ33-1", "protein_name": "Obg-like ATPase 1", "gene_name": "OLA1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPPKKGGDGIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPVRDIEIIHEELQLKDEEMVGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELRLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKEEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQPKKK", "length": 396 }, "evidence": [ { "id": "A0A5G2RAQ9", "url": "https://omabrowser.org/oma/group/A0A5G2RAQ9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55ET7-1", "protein_name": "Obg-like ATPase 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKTPAKLVDCSSTLSRVGNHLQMGVVGMPNVGKSSLFNLLCKMSIPAENFPFCTIDPNLSRCAVPDERYTWLCEHWKPKSEVPSYLQITDIAGLVKGASTGAGLGNAFLSHIQQVDGIYHMIRAFENDEIIHVEDSVDPVRDLDIISKELIAKDIEFTTKALKTLQTSLKNKTIDKAKQVELGTYNKVLELLESGKHVRYGTYSNAETEHVRDLHLLTSKPAIYLINLSEEDFIRKKNKWLAKIKAWVDENGGGTMIPVSVSFEKALLDLSSDDERKAYEKEKGAVSIMPKIIKTGYSTLNLINFFTCGKDEVRSWCLQKGNKAPQAAGVIHTDFEKGFIMAETMAYSDFFELKSEAECKSRGKYRMEGKNYEVVDGDIIFFKFNVSNNKKK", "length": 393 }, "evidence": [ { "id": "A0A5G2RAQ9", "url": "https://omabrowser.org/oma/group/A0A5G2RAQ9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8SWU7-1", "protein_name": "Obg-like ATPase 1", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPKKHDEPERKPLIGRIGTNLRIGIVGVPNVGKSTFFNVLTQSAAPAENFPFCTIKPNESRVPVPDERFDYLVEYHKPASVVPAYLNVVDIAGLVKGAAEGQGLGNDFLSHISACDAIFHLCRAFEDPDVTHVEGEVDPVRDLEIISEELRLKDEENLLKNLDKLEKVVARGGDKKLKPEYDSMLKIKDILIDQKRHLRFEDWNAHDIEALNKYLFLTSKPVIYLVNLSDKDFIRKKNKWLPKIKEWIDKNDPGALLIPFSGAFEHQLTEKDELERKAYETETKCKSMLEKIVVTGYKGLQLEYFFTAGPDEVKAWTIQKGTKAPQAAGRIHTDFEKGFIMAEVMHFEDFKAEGSEANAKAAGKYRQQGRNYTVEDGDIIFFKFNAGAGLKDAKKK", "length": 397 }, "evidence": [ { "id": "A0A5G2RAQ9", "url": "https://omabrowser.org/oma/group/A0A5G2RAQ9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9CZ30-1", "protein_name": "Obg-like ATPase 1", "gene_name": "Ola1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPKKGGDGIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPILDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKDEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQPKKK", "length": 396 }, "evidence": [ { "id": "A0A5G2RAQ9", "url": "https://omabrowser.org/oma/group/A0A5G2RAQ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NTK5-1", "protein_name": "Obg-like ATPase 1", "gene_name": "OLA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPKKGGDGIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFTAGPDEVRAWTIRKGTKAPQAAGKIHTDFEKGFIMAEVMKYEDFKEEGSENAVKAAGKYRQQGRNYIVEDGDIIFFKFNTPQQPKKK", "length": 396 }, "evidence": [ { "id": "A0A5G2RAQ9", "url": "https://omabrowser.org/oma/group/A0A5G2RAQ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" } ], "pmid": "" }, { "name": "ribosomal large subunit binding", "id": "GO:0043023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043023", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ATP metabolic process", "id": "GO:0046034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046034", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAQ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 395, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAQ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAQ9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" }, { "id": "MF_03167", "database": "HAMAP", "url": "https://hamap.expasy.org/signature/MF_03167" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Nuclear export signal", "eco_id": "ECO_0000256", "start_pos": 266, "end_pos": 273, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RAQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" }, { "id": "PS51710", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51710" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OBG-type G", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 282, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RAQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAQ9" }, { "id": "PS51880", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51880" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TGS", "eco_id": "ECO_0000259", "start_pos": 303, "end_pos": 386, "start_aa": "Gln", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 229, "end_pos": 231 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RD43-1", "uniprot_ac": "A0A5G2RD43", "uniprot_id": "A0A5G2RD43_PIG", "mass": { "chemical_mass": 81615.0, "monoisotopic_mass": 81615.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110256000", "type": "recommended", "evidence": [ { "id": "A0A5G2RD43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" } ] } ], "protein_names": [ { "name": "Amine oxidase", "type": "recommended", "evidence": [ { "id": "A0A5G2RD43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43/entry#names_and_taxonomy" } ] }, { "name": "1.4.3.-", "type": "synonym", "evidence": [ { "id": "A0A5G2RD43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110256000", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43", "locus": {} } ], "crossref": [ { "id": "A0A5G2RD43", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RD43", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017383", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017383", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110256000", "url": "https://www.ncbi.nlm.nih.gov/gene/110256000", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015798", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015798", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015802", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015802", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110256000", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110256000", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GFHIHDF", "url": "https://omabrowser.org/oma/group/GFHIHDF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S1G8", "url": "https://www.orthodb.org/?gene=F1S1G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10638", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10638", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10638:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10638:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02728", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02728", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RD43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RD43-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RI05", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RI05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RI05-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RI05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1G8", "url": "https://www.uniprot.org/uniprotkb/F1S1G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1G8-1", "url": "https://www.uniprot.org/uniprotkb/F1S1G8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AAEGVGRECKPGQPPRCPSGAPGAQPWTHPGQSQLFADLSREELTAVMNFLTQKLGPGLVDAAQARPADNCIFSVELQLPPKAAALAHLDRGSPPPAREALAIIFFGGQPQPNVTELVVGPLPQPSYVRDVTVERHGGPLPYHRRPVLMREYLDIDQMIFRRELPQAAGLLHHCCFYSSQSQNLVTMNSAPRGLQSGDRATWFGLYYNISGAGFYLHPVGLELLVDHKALDPALWTIQKVFFQGRYYESLAHLEEQFEAGLVNVVVIPDNGTDASWSLKSRVPPGPAPPLQFYPQGPRFSVQGSHVASSLWTFSFGLGAFSGPRIFDIRFQGERVAYEVSVQEALAVYGGNSPSALRGRYADASFGLGHFSTPLTRGVDCPYLATYVDWPFLLESQVSKTLRDAFCVFEQNQGLPVRRHHSDIRSHYFGGLAKTVLVVRSVSTMLNYDYVWDMIFHPNGAIEVKLHTTGYIGSSFLFGDVQSFGNRVGEHTLGTVHTHSAHFKVDLDVGGLENWVWAEDTTFVPTAVPWSPERQIQRLQLTRKVLETEEQAAFPVGGAAPRYLYLASNQSNKWGHPRGYRIQIVSFSGEPLPQSSSMAGAFSWERYQLAVTRRKEEEPSSSSIYNLNDPWTPTLDFTDFINNETIAGQDLVAWVTAGFLHIPHAEDIPNTVTVANSVGFFLRPYNFFDQDPSINSADSIYFREDQDPGACDVNPLACLSEAAACAPDLPAFSHGGFFHN", "length": 739, "header": "tr|A0A5G2RD43-1|A0A5G2RD43_PIG Isoform 1 of Amine oxidase OS=Sus scrofa OX=9823 GN=LOC110256000 PE=3 SV=1 CANONICAL=A0A5G2RD43-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RD43-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43/entry#A0A5G2RD43-1", "sequence": { "sequence": "AAEGVGRECKPGQPPRCPSGAPGAQPWTHPGQSQLFADLSREELTAVMNFLTQKLGPGLVDAAQARPADNCIFSVELQLPPKAAALAHLDRGSPPPAREALAIIFFGGQPQPNVTELVVGPLPQPSYVRDVTVERHGGPLPYHRRPVLMREYLDIDQMIFRRELPQAAGLLHHCCFYSSQSQNLVTMNSAPRGLQSGDRATWFGLYYNISGAGFYLHPVGLELLVDHKALDPALWTIQKVFFQGRYYESLAHLEEQFEAGLVNVVVIPDNGTDASWSLKSRVPPGPAPPLQFYPQGPRFSVQGSHVASSLWTFSFGLGAFSGPRIFDIRFQGERVAYEVSVQEALAVYGGNSPSALRGRYADASFGLGHFSTPLTRGVDCPYLATYVDWPFLLESQVSKTLRDAFCVFEQNQGLPVRRHHSDIRSHYFGGLAKTVLVVRSVSTMLNYDYVWDMIFHPNGAIEVKLHTTGYIGSSFLFGDVQSFGNRVGEHTLGTVHTHSAHFKVDLDVGGLENWVWAEDTTFVPTAVPWSPERQIQRLQLTRKVLETEEQAAFPVGGAAPRYLYLASNQSNKWGHPRGYRIQIVSFSGEPLPQSSSMAGAFSWERYQLAVTRRKEEEPSSSSIYNLNDPWTPTLDFTDFINNETIAGQDLVAWVTAGFLHIPHAEDIPNTVTVANSVGFFLRPYNFFDQDPSINSADSIYFREDQDPGACDVNPLACLSEAAACAPDLPAFSHGGFFHN", "length": 739, "header": "tr|A0A5G2RD43-1|A0A5G2RD43_PIG Isoform 1 of Amine oxidase OS=Sus scrofa OX=9823 GN=LOC110256000 PE=3 SV=1 CANONICAL=A0A5G2RD43-1" }, "locus": { "chromosome": "12", "start_pos": 20006952, "end_pos": 19996940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082062.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082062.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068609.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068609.1" } ] } }, { "isoform_ac": "A0A5G2RI05-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43/entry#A0A5G2RI05-1", "sequence": { "sequence": "WSEEGVGRECKPGQPPRCPSGAPGAQPWTHPGQSQLFADLSREELTAVMNFLTQKLGPGLVDAAQARPADNCIFSVELQLPPKAAALAHLDRGSPPPAREALAIIFFGGQPQPNVTELVVGPLPQPSYVRDVTVERHGGPLPYHRRPVLMREYLDIDQMIFRRELPQAAGLLHHCCFYSSQSQNLVTMNSAPRGLQSGDRATWFGLYYNISGAGFYLHPVGLELLVDHKALDPALWTIQKVFFQGRYYESLAHLEEQFEAGLVNVVVIPDNGTDASWSLKSRVPPGPAPPLQFYPQGPRFSVQGSHVASSLWTFSFGLGAFSGPRIFDIRFQGERVAYEVSVQEALAVYGGNSPSALRGRYADASFGLGHFSTPLTRGVDCPYLATYVDWPFLLESQNQGLPVRRHHSDIRSHYFGGLAKTVLVVRSVSTMLNYDYVWDMIFHPNGAIEVKLHTTGYIGSSFLFGDVQSFGNRVGEHTLGTVHTHSAHFKVDLDVGGLENWVWAEDTTFVPTAVPWSPERQIQRLQLTRKVLETEEQAAFPVGGAAPRYLYLASNQSNKWGHPRGYRIQIVSFSGEPLPQSSSMAGAFSWERYQLAVTRRKEEEPSSSSIYNLNDPWTPTLDFTDFINNETIAGQDLVAWVTAGFLHIPHAEDIPNTVTVANSVGFFLRPYNFFDQDPSINSADSIYFREDQDPGACDVNPLACLSEAAACAPDLPAFSHGGFFHN", "length": 726, "header": "tr|A0A5G2RI05-1|A0A5G2RD43_PIG Computationally mapped isoform of Amine oxidase OS=Sus scrofa OX=9823 GN=LOC110256000 PE=3 SV=2 CANONICAL=A0A5G2RD43-1" }, "locus": { "chromosome": "12", "start_pos": 20006025, "end_pos": 19996940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080085.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080085.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071097.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071097.2" } ] } }, { "isoform_ac": "F1S1G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43/entry#F1S1G8-1", "sequence": { "sequence": "MNFLTQKLGPGLVDAAQARPADNCIFSVELQLPPKAAALAHLDRGSPPPAREALAIIFFGGQPQPNVTELVVGPLPQPSYVRDVTVERHGGPLPYHRRPVLMREYLDIDQMIFRRELPQAAGLLHHCCFYSSQSQNLVTMNSAPRGLQSGDRATWFGLYYNISGAGFYLHPVGLELLVDHKALDPALWTIQKVFFQGRYYESLAHLEEQFEAGLVNVVVIPDNGTDASWSLKSRVPPGPAPPLQFYPQGPRFSVQGSHVASSLWTFSFGLGAFSGPRIFDIRFQGERVAYEVSVQEALAVYGGNSPSALRGRYADASFGLGHFSTPLTRGVDCPYLATYVDWPFLLESQVSKTLRDAFCVFEQNQGLPVRRHHSDIRSHYFGGLAKTVLVVRSVSTMLNYDYVWDMIFHPNGAIEVKLHTTGYIGSSFLFGDVQSFGNRVGEHTLGTVHTHSAHFKVDLDVGGLENWVWAEDTTFVPTAVPWSPERQIQRLQLTRKVLETEEQAAFPVGGAAPRYLYLASNQSNKWGHPRGYRIQIVSFSGEPLPQSSSMAGAFSWERYQLAVTRRKEEEPSSSSIYNLNDPWTPTLDFTDFINNETIAGQDLVAWVTAGFLHIPHAEDIPNTVTVANSVGFFLRPYNFFDQDPSINSADSIYFREDQDPGACDVNPLACLSEAAACAPDLPAFSHGGFFHN", "length": 692, "header": "tr|F1S1G8-1|A0A5G2RD43_PIG Computationally mapped isoform of Amine oxidase OS=Sus scrofa OX=9823 GN=LOC110256000 PE=3 SV=3 CANONICAL=A0A5G2RD43-1" }, "locus": { "chromosome": "12", "start_pos": 20005881, "end_pos": 19996940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018922.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018922.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018417.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018417.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RI05", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RI05" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110256000", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110256000", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A8Q8-1", "protein_name": "Amine oxidase", "gene_name": "AOC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNMKTVLVLLLLALATIFALVCVLLTRARAPGACQQQPSAQEEADDGHSRVFADLTPEELAQVVQYLRGSLGVPLADAARAKPSDNCIASVDVQLPAKAEVLRFLDAGGARPPREALAVLYFGAQAEPNVTEYVVGPLPAPTYHRDVTVQKYGGKVPYHRRPALPAEYKQIADFFRGRVFPSAPSFMDQVMEYDGANLAAVTTAPRGSRSGDRLTWFVMFQNVSGFFLHPVGLEVLVDHSSLDLTQWAVRRVFYNGQYYRDMSELERTYVQGGVHVEKVRRAPRDGDFSSMRPRVPVAATFPLQYEPQGPRYSIRSNLVIFQAWSFAFGMSVMTGMRLFDIRYNGERVVYEMSVQEALSVYGSNCPGGMSTRYMDGSFGIGRYASPLVRGVDCPYTATYVDTHTLHEGLSSSRRTAALCIFEQNLGSPLRRHYSNLQSLYYGGMVNSALVLRSITTVGNYDYVWDFIFYQNGAIEGKVQATGYTSSSFFHGNGLQYGNRVWEHTLGTIHTHFVNYKVDLDVGEVKNSLVAHDMAFEMVQAPWDPEQQIERPRLTEKVLDMEDQAAFRLHSTMPRYLYFATNQKNKWGHQRGYRIQIISFAGDHVPEASSMERAISWARYKLAVTRRKEEEPTSTSVYNQNDPWTPTVTFADFINNETITNEDLVAWITAGFLHIPHSEDIPNTLTVGNSVGFLLRPYNYYNLDPSIYSPDGVFFTSEQNFMACEVNPITCLSQTASCLPSLPPFTYDGFQNISRL", "length": 755 }, "evidence": [ { "id": "A0A5G2RD43", "url": "https://omabrowser.org/oma/group/A0A5G2RD43/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" } ], "pmid": "" }, { "name": "primary methylamine oxidase activity", "id": "GO:0008131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008131", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" } ], "pmid": "" }, { "name": "quinone binding", "id": "GO:0048038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048038", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "amine metabolic process", "id": "GO:0009308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009308", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RD43-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 739, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RD43-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RD43" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RD43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" }, { "id": "PF02727", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02727" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Copper amine oxidase N2-terminal", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 127, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RD43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" }, { "id": "PF02728", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02728" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Copper amine oxidase N3-terminal", "eco_id": "ECO_0000259", "start_pos": 145, "end_pos": 245, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RD43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD43" }, { "id": "PF01179", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Copper amine oxidase catalytic", "eco_id": "ECO_0000259", "start_pos": 301, "end_pos": 699, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 642, "end_pos": 644 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8I5-1", "uniprot_ac": "A0A5G2R8I5", "uniprot_id": "A0A5G2R8I5_PIG", "mass": { "chemical_mass": 100245.0, "monoisotopic_mass": 100245.0 }, "refseq": {}, "gene_names": [ { "name": "CORO7", "type": "recommended", "evidence": [ { "id": "A0A5G2R8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ] } ], "protein_names": [ { "name": "Coronin", "type": "recommended", "evidence": [ { "id": "A0A5G2R8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology.", "evidence": [ { "database": "UniProtKB", "id": "F1RK53", "url": "https://www.uniprot.org/uniprotkb/F1RK53#function" }, { "database": "UniProtKB", "id": "ARBA00024838", "url": "https://www.uniprot.org/uniprotkb/ARBA00024838#function" }, { "database": "UniProtKB", "id": "A0A5G2RCN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCN1#function" }, { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CORO7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5", "locus": { "chromosome": "3", "start_pos": 37985151, "end_pos": 37928096, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007944", "url": "https://www.ensembl.org/id/ENSSSCG00000007944" } ] } } ], "crossref": [ { "id": "A0A5G2R8I5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8I5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000007944", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007944", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10856", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10856", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10856:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10856:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RK53", "url": "https://www.uniprot.org/uniprotkb/F1RK53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RK53-1", "url": "https://www.uniprot.org/uniprotkb/F1RK53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRFKVSKFRHTEARPPRREAWISDIRAGTAPSCGNHIKSSCSLIAFISDRPGVLGIVPLEGQGEDKRHVTHLGCHSDLVTDLDFSPFDDFLLATASADRTVKLWRLPAPGQALPSGPGLVLGPEDVPVEVLQFHPSADGVLLSAAGKALKVWDAARQQPLTELAAHGDLVQSAIWSQDGALVGTTCKVRDKQLRIFDPRAKPEASQSTQAHENSRDGRLVWTGTREHLVSTGFNQMREREVKLWDIRLFSGALASLTLDASPRSLMPLLDPDSGLLVLAGKGESQLSCYEVAPQQPVLSPVTQCLLESALRGAALVPRRALAVLGCEVLRVLQLSDSAIVPISYHVPRKAAEFHEDLFPDAAGSTPASDAQAWWAGSNQQVQRVSLHPARRPLPSFTSRLVSPAQPSPDAAQPAKTPAGDADPSDGFSSPPSSLTSPSTPSSLGPSLSSTSGIGTSPSQRSLQSLLGPSSKFRHTQGTVLHRDSHITNLKGLNLTTPGESDGFCANRLRVAVPLLSSGGQVAVLELRKPGRLPDTALPTLQNGAAVTDLAWDPFDLHRLAVAGEDARIRLWRVPPEGLEEVLTTPEAVLTGHTEKIYSLRFHPLAADVLASSSYDLTIRIWDLQAGVERLRLQGHRDQIFGLAWSPNGQQLATVCKDGRLRVYEPRSSPEPLQEGPGPEGARGARVVWVCDGHCLLVSGFDSRSERQLLLFSAEALASGPLAVLGLDVAPSTLLPSYDPDTSLVLLTGKGDTRVFLYELLPEAPFFLECNSFTSPDPHKGFVLLPKTECEVREVEFARCLRLRQTSLEPVAFRLPRVRKEFFQDDVFPDTAVSWEPVLSAEAWLGGANGQPRLLSLQPLGMTPVSQAPREAPARRAPPSALYLEEKSDQQKKEELLSAMVAKLGNREDPLPQDSFEGVDEDEWD", "length": 925, "header": "tr|A0A5G2R8I5-1|A0A5G2R8I5_PIG Isoform 1 of Coronin OS=Sus scrofa OX=9823 GN=CORO7 PE=1 SV=1 CANONICAL=A0A5G2R8I5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R8I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5/entry#A0A5G2R8I5-1", "sequence": { "sequence": "MNRFKVSKFRHTEARPPRREAWISDIRAGTAPSCGNHIKSSCSLIAFISDRPGVLGIVPLEGQGEDKRHVTHLGCHSDLVTDLDFSPFDDFLLATASADRTVKLWRLPAPGQALPSGPGLVLGPEDVPVEVLQFHPSADGVLLSAAGKALKVWDAARQQPLTELAAHGDLVQSAIWSQDGALVGTTCKVRDKQLRIFDPRAKPEASQSTQAHENSRDGRLVWTGTREHLVSTGFNQMREREVKLWDIRLFSGALASLTLDASPRSLMPLLDPDSGLLVLAGKGESQLSCYEVAPQQPVLSPVTQCLLESALRGAALVPRRALAVLGCEVLRVLQLSDSAIVPISYHVPRKAAEFHEDLFPDAAGSTPASDAQAWWAGSNQQVQRVSLHPARRPLPSFTSRLVSPAQPSPDAAQPAKTPAGDADPSDGFSSPPSSLTSPSTPSSLGPSLSSTSGIGTSPSQRSLQSLLGPSSKFRHTQGTVLHRDSHITNLKGLNLTTPGESDGFCANRLRVAVPLLSSGGQVAVLELRKPGRLPDTALPTLQNGAAVTDLAWDPFDLHRLAVAGEDARIRLWRVPPEGLEEVLTTPEAVLTGHTEKIYSLRFHPLAADVLASSSYDLTIRIWDLQAGVERLRLQGHRDQIFGLAWSPNGQQLATVCKDGRLRVYEPRSSPEPLQEGPGPEGARGARVVWVCDGHCLLVSGFDSRSERQLLLFSAEALASGPLAVLGLDVAPSTLLPSYDPDTSLVLLTGKGDTRVFLYELLPEAPFFLECNSFTSPDPHKGFVLLPKTECEVREVEFARCLRLRQTSLEPVAFRLPRVRKEFFQDDVFPDTAVSWEPVLSAEAWLGGANGQPRLLSLQPLGMTPVSQAPREAPARRAPPSALYLEEKSDQQKKEELLSAMVAKLGNREDPLPQDSFEGVDEDEWD", "length": 925, "header": "tr|A0A5G2R8I5-1|A0A5G2R8I5_PIG Isoform 1 of Coronin OS=Sus scrofa OX=9823 GN=CORO7 PE=1 SV=1 CANONICAL=A0A5G2R8I5-1" }, "locus": { "chromosome": "3", "start_pos": 37984543, "end_pos": 37928216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086264.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086264.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066923.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066923.1" } ] } }, { "isoform_ac": "A0A5G2RCN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5/entry#A0A5G2RCN1-1", "sequence": { "sequence": "MNRFKVSKFRHTEARPPRREAWISDIRAGTAPSCGNHIKSSCSLIAFISDRPGVLGIVPLEGQGEDKRHVTHLGCHSELAAHGDLVQSAIWSQDGALVGTTCKVRDKQLRIFDPRAKPEASQSTQAHENSRDGRLVWTGTREHLVSTGFNQMREREVKLWDIRLFSGALASLTLDASPRSLMPLLDPDSGLLVLAGKGESQLSCYEVAPQQPVLSPVTQCLLESALRGAALVPRRALAVLGCEVLRVLQLSDSAIVPISYHVPRKAAEFHEDLFPDAAGSTPASDAQAWWAGSNQQVQRVSLHPARRPLPSFTSRLVSPAQPSPDAAQPAKTPAGDADPSDGFSSPPSSLTSPSTPSSLGPSLSSTSGIGTSPSQRSLQSLLGPSSKFRHTQGTVLHRDSHITNLKGLNLTTPGESDGFCANRLRVAVPLLSSGGQVAVLELRKPGRLPDTALPTLQNGAAVTDLAWDPFDLHRLAVAGEDARIRLWRVPPEGLEEVLTTPEAVLTGHTEKIYSLRFHPLAADVLASSSYDLTIRIWDLQAGVERLRLQGHRDQIFGLAWSPNGQQLATVCKDGRLRVYEPRSSPEPLQEGPGPEGARGARVVWVCDGHCLLVSGFDSRSERQLLLFSAEALASGPLAVLGLDVAPSTLLPSYDPDTSLVLLTGKGDTRVFLYELLPEAPFFLECNSFTSPDPHKGFVLLPKTECEVREVEFARCLRLRQTSLEPVAFRLPRVRKEFFQDDVFPDTAVSWEPVLSAEAWLGGANGQPRLLSLQPLGMTPVSQAPREAPARRAPPSALYLEEKSDQQKKEELLSAMVAKLGNREDPLPQDSFEGVDEDEWD", "length": 840, "header": "tr|A0A5G2RCN1-1|A0A5G2RCN1_PIG Computationally mapped isoform of Coronin OS=Sus scrofa OX=9823 GN=CORO7 PE=1 SV=1 CANONICAL=A0A5G2R8I5-1" }, "locus": { "chromosome": "3", "start_pos": 37984543, "end_pos": 37928216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076668.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076668.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074171.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074171.1" } ] } }, { "isoform_ac": "F1RK53-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5/entry#F1RK53-1", "sequence": { "sequence": "MNRFKVSKFRHTEARPPRREAWISDIRAGTAPSCGNHIKSSCSLIAFISDRPGVLGIVPLEGQGEDKRHVTHLGCHSDLVTDLDFSPFDDFLLATASADRTVKLWRLPAPGQALPSGPGLVLGPEDVPVEVLQFHPSADGVLLSAAGKALKVWDAARQQPLTELAAHGDLVQSAIWSQDGALVGTTCKVRDKQLRIFDPRAKPEASQSTQAHENSRDGRLVWTGTREHLVSTGFNQMREREVKLWDIRLFSGALASLTLDASPRSLMPLLDPDSGLLVLAGKGESQLSCYEVAPQQPVLSPVTQCLLESALRGAALVPRRALAVLGCEVLRVLQLSDSAIVPISYHVPRKAAEFHEDLFPDAAGSTPASDAQAWWAGSNQQVQRVSLHPARRPLPSFTSRLVSPAQPSPDAAQPAKTPAGDADPSDGFSSPPSSLTSPSTPSSLGPSLSSTSGIGTSPSQRSLQSLLGPSSKFRHTQGTVLHRDSHITNLKGLNLTTPGESDGFCANRLRVAVPLLSSGGQVAVLELRKPGRLPDTALPTLQNGAAVTDLAWDPFDLHRLAVAGEDARIRLWRVPPEGLEEVLTTPEAVLTGQGPSITPTLHPQATRRRSILCASTRWRATGISPNGQQLATVCKDGRLRVYEPRSSPEPLQEGPGPEGARGARVVWVCDGHCLLVSGFDSRSERQLLLFSAEALASGPLAVLGLDVAPSTLLPSYDPDTSLVLLTGKGDTRVFLYELLPEAPFFLECNSFTSPDPHKGFVLLPKTECEVREVEFARCLRLRQTSLEPVAFRLPRVRKEFFQDDVFPDTAVSWEPVLSAEAWLGGANGQPRLLSLQPLGMTPVSQAPREAPARRAPPSALYLEEKSDQQKKEELLSAMVAKLGNREDPLPQDSFEGVDEDEWVSGRVGPACLPGLPHAPRSKRHPLARPAHPPATPALFPQD", "length": 942, "header": "tr|F1RK53-1|A0A5G2R8I5_PIG Computationally mapped isoform of Coronin OS=Sus scrofa OX=9823 GN=CORO7 PE=1 SV=4 CANONICAL=A0A5G2R8I5-1" }, "locus": { "chromosome": "3", "start_pos": 37984543, "end_pos": 37928216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008707.5", "url": "https://www.ensembl.org/id/ENSSSCT00000008707.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008483.4", "url": "https://www.ensembl.org/id/ENSSSCP00000008483.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 366, "start_aa": "Thr", "end_pos": 366, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr366", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 440, "start_aa": "Thr", "end_pos": 440, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr440", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RK53", "url": "https://www.uniprot.org/uniprotkb/F1RK53" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "positive regulation of hippo signaling", "id": "GO:0035332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035332", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8I5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 925, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8I5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8I5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I5" }, { "id": "SM01166", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01166" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF1899", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 64, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 366, 440 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 494, "end_pos": 496 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAR3-1", "uniprot_ac": "A0A5G2RAR3", "uniprot_id": "A0A5G2RAR3_PIG", "mass": { "chemical_mass": 35111.0, "monoisotopic_mass": 35111.0 }, "refseq": { "ac": "XP_020949335", "name": "carbonic anhydrase 5A, mitochondrial isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949335" }, "gene_names": [ { "name": "CA5A", "type": "recommended", "evidence": [ { "id": "A0A5G2RAR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3" } ] }, { "name": "CA5A", "type": "synonym", "evidence": [ { "id": "XP_020949335", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949335" } ] } ], "protein_names": [ { "name": "Carbonic anhydrase", "type": "recommended", "evidence": [ { "id": "A0A5G2RAR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3/entry#names_and_taxonomy" } ] }, { "name": "4.2.1.1", "type": "synonym", "evidence": [ { "id": "A0A5G2RAR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3/entry#names_and_taxonomy" } ] }, { "name": "carbonic anhydrase 5A, mitochondrial isoform X4", "type": "synonym", "evidence": [ { "id": "XP_020949335", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949335" } ] } ], "function": [ { "annotation": "Reversible hydration of carbon dioxide.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FC13", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FC13#function" }, { "database": "UniProtKB", "id": "RU367011", "url": "https://www.uniprot.org/uniprotkb/RU367011#function" }, { "database": "UniProtKB", "id": "A0A287A9K7", "url": "https://www.uniprot.org/uniprotkb/A0A287A9K7#function" }, { "database": "UniProtKB", "id": "A0A5G2QVV1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV1#function" }, { "database": "UniProtKB", "id": "A0A5G2R0X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X3#function" }, { "database": "UniProtKB", "id": "A0A5G2RAR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CA5A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3", "locus": { "chromosome": "6", "start_pos": 1538777, "end_pos": 1506042, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000035629", "url": "https://www.ensembl.org/id/ENSSSCG00000035629" } ] } } ], "crossref": [ { "id": "A0A5G2RAR3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000035629", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035629", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110260889", "url": "https://www.ncbi.nlm.nih.gov/gene/110260889", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EKAMVNN", "url": "https://omabrowser.org/oma/group/EKAMVNN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952:SF89", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952:SF89", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1475029", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475029", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020949335", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949335", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10748", "url": "https://www.rhea-db.org/rhea/10748", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A9K7", "url": "https://www.uniprot.org/uniprotkb/A0A287A9K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A9K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A9K7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVV1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0X3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FC13", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FC13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FC13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FC13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRAPLSCRGHVTSSAFSGLVRQRWGTLRGHWLRPERWCVQAPCGPRRRNNAVHPLWKDPASSPGGTRPSPINIRWRDSVYDPRLQPLSVSYDAASCLHVWNTGYLLQVEFDDSTDWSGISGGPLENPYRLKQFHFHWGAVDEWGSEHTVEDHAYPAELHLVHWNAVKYQNYREAATGEHGLAVIGVFLKLGARHEALQELLEVLPDIKHKDSRAALGPFQPSCLLPTCRDYWTYPGSLTTPPLSESVTWIIYKKPIEVAQDQLAAFRTLLFSALGEKEEAMVNNYRPLQPLMKRKVRSSFQTPEDGPAA", "length": 310, "header": "tr|A0A5G2RAR3-1|A0A5G2RAR3_PIG Isoform 1 of Carbonic anhydrase OS=Sus scrofa OX=9823 GN=CA5A PE=3 SV=2 CANONICAL=A0A5G2RAR3-1" }, "isoforms": [ { "isoform_ac": "A0A287A9K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3/entry#A0A287A9K7-1", "sequence": { "sequence": "MLRAPLSCRGHVTSSAFSGLVRQRWGTLRGHWLRPERWCVQAPCGPRRRNNAVHPLWKDPASSPGGTRPSPINIRWRDSVYDPRLQPLSVSYDAASCLHVWNTGYLLQVEFDDSTDWSGISGGPLENPYRLKQFHFHWGAVDEWGSEHTVEDHAYPAELHLVHWNAVKYQNYREAATGEHGLAVIGVFLKDSRAALGPFQPSCLLPTCRDYWTYPGSLTTPPLSESVTWIIYKKPIEVAQDQLAAFRTLLFSALGEKEEAMVNNYRPLQPLMKRKVRSSFQTPEDGPAA", "length": 289, "header": "tr|A0A287A9K7-1|A0A5G2RAR3_PIG Computationally mapped isoform of Carbonic anhydrase OS=Sus scrofa OX=9823 GN=CA5A PE=3 SV=2 CANONICAL=A0A5G2RAR3-1" }, "locus": { "chromosome": "6", "start_pos": 1528365, "end_pos": 1506167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057346.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057346.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040568.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040568.2" } ] } }, { "isoform_ac": "A0A5G2QVV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3/entry#A0A5G2QVV1-1", "sequence": { "sequence": "MLRAPLSCRGHVTSSAFSGLVRQRWGTLRGHWLRPERWCVQAPCGPRRRNNAVHPLWKDPASSPGGTRPSPINIRWRDSVYDPRLQPLSVSYDAASCLHVWNTGYLLQVEFDDSTDWSGISGGPLENPYRLKQFHFHWGAVDEWGSEHTVEDHAYPAELHLVHWNAVKYQNYREAATGEHGLAVIGVFLKLGARHEALQELLEVLPDIKHKVRDTDMPAAETRDSI", "length": 226, "header": "tr|A0A5G2QVV1-1|A0A5G2RAR3_PIG Computationally mapped isoform of Carbonic anhydrase OS=Sus scrofa OX=9823 GN=CA5A PE=3 SV=2 CANONICAL=A0A5G2RAR3-1" }, "locus": { "chromosome": "6", "start_pos": 1537655, "end_pos": 1506167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082715.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082715.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069084.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069084.2" } ] } }, { "isoform_ac": "A0A5G2R0X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3/entry#A0A5G2R0X3-1", "sequence": { "sequence": "MLRAPLSCRGHVTSSAFSGLVRQRWGTLRGHWLRPERWCVQAPCGPRRRNNAVHPLWKDPASSPGGTRPSPINIRWRDSVYDPRLQPLSVSYDAASCLHVWNTGYLLQVEFDDSTDWSGISGGPLENPYRLKQFHFHWGAVDEWGSEHTVEDHAYPAELHLVHWNAVKYQNYREAATGEHGLAVIGVFLKLGARHEALQELLEVLPDIKHKDSRAALGPFQPSCLLPTCRDYWTYPGSLTTPPLSESVTWIIYKKPIEVAQDQRASAGDPNTKEAMSEMRVLARCSRLRIDEEKRRF", "length": 297, "header": "tr|A0A5G2R0X3-1|A0A5G2RAR3_PIG Computationally mapped isoform of Carbonic anhydrase OS=Sus scrofa OX=9823 GN=CA5A PE=3 SV=1 CANONICAL=A0A5G2RAR3-1" }, "locus": { "chromosome": "6", "start_pos": 1525899, "end_pos": 1506167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077090.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077090.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070763.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070763.1" } ] } }, { "isoform_ac": "A0A5G2RAR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3/entry#A0A5G2RAR3-1", "sequence": { "sequence": "MLRAPLSCRGHVTSSAFSGLVRQRWGTLRGHWLRPERWCVQAPCGPRRRNNAVHPLWKDPASSPGGTRPSPINIRWRDSVYDPRLQPLSVSYDAASCLHVWNTGYLLQVEFDDSTDWSGISGGPLENPYRLKQFHFHWGAVDEWGSEHTVEDHAYPAELHLVHWNAVKYQNYREAATGEHGLAVIGVFLKLGARHEALQELLEVLPDIKHKDSRAALGPFQPSCLLPTCRDYWTYPGSLTTPPLSESVTWIIYKKPIEVAQDQLAAFRTLLFSALGEKEEAMVNNYRPLQPLMKRKVRSSFQTPEDGPAA", "length": 310, "header": "tr|A0A5G2RAR3-1|A0A5G2RAR3_PIG Isoform 1 of Carbonic anhydrase OS=Sus scrofa OX=9823 GN=CA5A PE=3 SV=2 CANONICAL=A0A5G2RAR3-1" }, "locus": { "chromosome": "6", "start_pos": 1528365, "end_pos": 1506167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068954.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068954.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071225.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071225.2" } ] } }, { "isoform_ac": "A0A8W4FC13-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3/entry#A0A8W4FC13-1", "sequence": { "sequence": "MLRAPLSCRGHVTSSAFSGLVRQRWGTLRGHWLRPERWCVQAPCGPRRRNNAVHPLWKDPASSPGGTRPSPINIRWRDSVYDPRLQPLSVSYDAASCLHVWNTGYLLQVEFDDSTDWSGISGGPLENPYRLKQFHFHWGAVDEWGSEHTVEDHAYPAELHLVHWNAVKYQNYREAATGEHGLAVIGVFLKLGARHEALQELLEVLPDIKHKAGKLCKIQRKWCRRDPWRRRLGPALVLTPVPEPRSPHLKNRRFRLKRERGVPVVAQWLTNLTRNHEVAGSILGLAQWVKDPALL", "length": 295, "header": "tr|A0A8W4FC13-1|A0A5G2RAR3_PIG Computationally mapped isoform of Carbonic anhydrase OS=Sus scrofa OX=9823 GN=CA5A PE=3 SV=1 CANONICAL=A0A5G2RAR3-1" }, "locus": { "chromosome": "6", "start_pos": 1523903, "end_pos": 1506167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101840.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101840.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076860.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076860.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FC13", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FC13" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1475029", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475029", "resource": "Reactome", "description": "Reversible hydration of carbon dioxide" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BAD9-1", "protein_name": "Carbonic anhydrase", "gene_name": "CA5A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRPPVLGWSHLKSSGLSLLAKQIWGTLRSHLLRPARWCSQVPCAQRRRNDALHPVWKGPASVPGGTRQSPINIRWRDSVYDPQLQPLGVSYNAEACLYVWNTGYLFQVEFDDSTEGSGISGGPLENHYRLKQFHFHWGAVNEWGSEHTVDDRVYPAELHLVHWNAVKYQNYTDAVTGADGLAVVGVFLKLGARHEELQELVAVLPDIKHKDARAALGPFQPSCLLPACQDYWTYPGSLTTPPLSESVTWIIHKKPIEVAQDQLAAFRSLLFSVPGEEEKTMVNNYRPLQPLMNRKVRSSFQATHEGARL", "length": 310 }, "evidence": [ { "id": "A0A5G2RAR3", "url": "https://omabrowser.org/oma/group/A0A5G2RAR3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P23589-1", "protein_name": "Carbonic anhydrase 5A, mitochondrial", "gene_name": "Ca5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRRDPRKPLAILRHVGLLCATGPQRWRFQHSCAEEHSNCARHPLWTGPVSSAEGTRQSPINIQWKDSVYDPQLAPLRVSYDAASCRYLWNTGYFFQVEFDDSCEDSGISGGPLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENGLAVIGVFLKLGAHHQALQKLVDVLPEVRHKDTQVAMGPFDPSCLLPACRDYWTYPGSLTTPPLAESVTWIVQKTPVEVSPSQLSTFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSSFRLDRTKMRS", "length": 299 }, "evidence": [ { "id": "A0A5G2RAR3", "url": "https://omabrowser.org/oma/group/A0A5G2RAR3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35218-1", "protein_name": "Carbonic anhydrase 5A, mitochondrial", "gene_name": "CA5A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGRNTWKTSAFSFLVEQMWAPLWSRSMRPGRWCSQRSCAWQTSNNTLHPLWTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATEASGISGGPLENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVIGVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLPTCWDYWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKVWASFQATNEGTRS", "length": 305 }, "evidence": [ { "id": "A0A5G2RAR3", "url": "https://omabrowser.org/oma/group/A0A5G2RAR3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43165-1", "protein_name": "Carbonic anhydrase 5A, mitochondrial", "gene_name": "Ca5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRAKMLGRGPYKPLAILRHMGPLCATRPQHWRFQHSYAEKHSNCARHPLWTGPVSSPGGTQQSPINIQWTDSVYDPKLAPLRVSYDAASCRYLWNTGYFFQVEFDDSCEESGISGGPLGNHYRLKQFHFHWGATDEWGSEHMVDGHAYPAELHLVHWNSMKYENYKKATTGENGLAVIGVFLKLGAHHEALQRLVDILPEVRHKDTQVTMGPFDPSCLLPACRDYWTYPGSLTTPPLAESVTWIVHKMPIEVSPSQLSTFRTLLFSGRGEDEEVMVNNFRPLQPLRGRNVRSSFQVPRVGTKS", "length": 304 }, "evidence": [ { "id": "A0A5G2RAR3", "url": "https://omabrowser.org/oma/group/A0A5G2RAR3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10748", "name": "", "equation": "hydrogencarbonate + H(+) = CO2 + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10748", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10748" } ] }, { "id": "R-SSC-1475028", "name": "Carbonic anhydrase dehydrates bicarbonate (mitochondria)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-29896" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1475028", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475028" } ] }, { "id": "R-SSC-1475032", "name": "Carbonic anhydrase hydrates carbon dioxide (mitochondria)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1475032", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475032" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29896", "participant_name": "HCO3- [mitochondrial matrix]", "crossref": [ { "id": "17544", "database": "ChEBI", "url": "" }, { "id": "11533114", "database": "PubChem Substance", "url": "" }, { "id": "C00288", "database": "COMPOUND", "url": "" }, { "id": "ZINC000006827693", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAR3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAR3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAR3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAR3" }, { "id": "PS51144", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51144" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-carbonic anhydrase", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 301, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RBR1-1", "uniprot_ac": "A0A5G2RBR1", "uniprot_id": "A0A5G2RBR1_PIG", "mass": { "chemical_mass": 187037.0, "monoisotopic_mass": 187037.0 }, "refseq": {}, "gene_names": [ { "name": "KIF21A", "type": "recommended", "evidence": [ { "id": "A0A5G2RBR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ] } ], "protein_names": [ { "name": "Kinesin-like protein KIF21A", "type": "recommended", "evidence": [ { "id": "A0A5G2RBR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Processive microtubule plus-end directed motor protein involved in neuronal axon guidance. Is recruited by KANK1 to cortical microtubule stabilizing complexes (CMSCs) at focal adhesions (FAs) rims where it promotes microtubule capture and stability. Controls microtubule polymerization rate at axonal growth cones and suppresses microtubule growth without inducing microtubule disassembly once it reaches the cell cortex.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QLW5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLW5#function" }, { "database": "UniProtKB", "id": "ARBA00053776", "url": "https://www.uniprot.org/uniprotkb/ARBA00053776#function" }, { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1#function" }, { "database": "UniProtKB", "id": "F1SHQ3", "url": "https://www.uniprot.org/uniprotkb/F1SHQ3#function" }, { "database": "UniProtKB", "id": "A0A287AI15", "url": "https://www.uniprot.org/uniprotkb/A0A287AI15#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KIF21A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1", "locus": { "chromosome": "5", "start_pos": 70889000, "end_pos": 71029809, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000779", "url": "https://www.ensembl.org/id/ENSSSCG00000000779" } ] } } ], "crossref": [ { "id": "ENSSSCG00000000779", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000779", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01372", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01372", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100520674", "url": "https://www.ncbi.nlm.nih.gov/gene/100520674", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47969:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47969:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23203", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23203", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23204", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983189", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983189", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AI15", "url": "https://www.uniprot.org/uniprotkb/A0A287AI15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AI15-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AI15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLW5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNI7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKT7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SHQ3", "url": "https://www.uniprot.org/uniprotkb/F1SHQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SHQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1SHQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGAPDESSVRVAVRIRPQLAKERIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIIEEEQGIISRAVKHLFKSIEEKKHASIKNGLPSPDFKVNAQFLELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSAGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHLSQTRMCPQIDTENAIDNKVISESSQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRNEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRTRITQLVSDQANQVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARSPYFSGSSAFSPTIMSSDKETIEIIDLAKKDLEKLKRKEKKKKKRLQKLEESNREERSVAGKEDNIDTDQEKKEEKGISERENNELEVEESQEVSDHEDEEEEEEEEEDDIEGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKIRSEYEKKLQAMNKELQRLQTAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLMESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPVQDTGSSAAAIETDASRAGAQQKMRIPVARVQALPAPITNGTRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVVNINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQIEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDVPLNSPGSEGSSLSSDLMKLCGEVKPKSKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSTSAREKDLPPPSGFPSKIGSISRQSSLSEKKLPEPSPITRRKVYEKAEKAKAKEQKHSDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRGIINPFPPSKGIRASPLQCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSTSTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIRMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWICALGVVPAHPVLLSGCRGGILKLWNMDNFVPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKTRNLQDGQISDTGDLGEDIASN", "length": 1669, "header": "tr|A0A5G2RBR1-1|A0A5G2RBR1_PIG Isoform 1 of Kinesin-like protein KIF21A OS=Sus scrofa OX=9823 GN=KIF21A PE=1 SV=2 CANONICAL=A0A5G2RBR1-1" }, "isoforms": [ { "isoform_ac": "A0A287AI15-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1/entry#A0A287AI15-1", "sequence": { "sequence": "MWGAPDESSVRVAVRIRPQLAKERIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIIEEEQGIISRAVKHLFKSIEEKKHASIKNGLPSPDFKVNAQFLELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSAGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHLSQTRMCPQIDTENAIDNKVISESSQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRNEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRTRITQLVSDQANQVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARSPYFSGSSAFSPTIMSSDKETIEIIDLAKKDLEKLKRKEKKKKKSVAGKEDNIDTDQEKKEEKGISERENNELEVEESQEVSDHEDEEEEEEEEEDDIEGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKIRSEYEKKLQAMNKELQRLQTAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLMESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPVQDTGSSAAAIETDASRAGAQQKMRIPVARVQALPAPITNGTRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVVNINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQIEITSATQNQLLFHMLKEKAELNPELDALLGHALQENVEDSTDEDVPLNSPGSEGSSLSSDLMKLCGEVKPKSKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSTSAREKDLPPPSGFPSKIGSISRQSSLSEKKLPEPSPITRRKVYEKAEKAKAKEQKHSDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKGIINPFPPSKGIRASPLQCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSTSTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIRMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWICALGVVPAHPVLLSGCRGGILKLWNMDNFVPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKTRNLQDGQISDTGDLGEDIASN", "length": 1636, "header": "tr|A0A287AI15-1|A0A5G2RBR1_PIG Computationally mapped isoform of Kinesin-like protein KIF21A OS=Sus scrofa OX=9823 GN=KIF21A PE=1 SV=1 CANONICAL=A0A5G2RBR1-1" }, "locus": { "chromosome": "5", "start_pos": 71029352, "end_pos": 70890678, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053315.1", "url": "https://www.ensembl.org/id/ENSSSCT00000053315.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043677.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043677.1" } ] } }, { "isoform_ac": "A0A5G2QLW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1/entry#A0A5G2QLW5-1", "sequence": { "sequence": "MWGAPDESSVRVAVRIRPQLAKERIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIIEEEQGIISRAVKHLFKSIEEKKHASIKNGLPSPDFKVNAQFLELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSAGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHLSQTRMCPQIDTENAIDNKVISESSQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRNEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRTRITQLVSDQANQVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARSPYFSGSSAFSPTIMSSDKETIEIIDLAKKDLEKLKRKEKKKKKSVAGKEDNIDTDQEKKEEKGISERENNELEVEESQEVSDHEDEEEEEEEEEDDIEGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKIRSEYEKKLQAMNKELQRLQTAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLMESRRNREIAQLKKDQRKRDVTALRRQVRPMSDKVAGKVTRKLSSSDAPVQDTGSSAAAIETDASRAGAQQKMRIPVARVQALPAPITNGTRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVVNINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQIEITSATQNQLLFHMLKEKAELNPELDALLGHALQENVEDSTDEDVPLNSPGSEGSSLSSDLMKLCGEVKPKSKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSTSAREKDLPPPSGFPSKIGSISRQSSLSEKKLPEPSPITRRKVYEKAEKAKAKEQKHSDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKGIINPFPPSKGIRASPLQCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSTSTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIRMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWICALGVVPAHPVLLSGCRGGILKLWNMDNFVPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKTRNLQDGQISDTGDLGEDIASN", "length": 1613, "header": "tr|A0A5G2QLW5-1|A0A5G2QLW5_PIG Computationally mapped isoform of Kinesin-like protein KIF21A OS=Sus scrofa OX=9823 GN=KIF21A PE=1 SV=2 CANONICAL=A0A5G2RBR1-1" }, "locus": { "chromosome": "5", "start_pos": 71029352, "end_pos": 70890678, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083953.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083953.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065577.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065577.2" } ] } }, { "isoform_ac": "A0A5G2QNI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1/entry#A0A5G2QNI7-1", "sequence": { "sequence": "MWGAPDESSVRVAVRIRPQLAKERIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIIEEEQGIISRAVKHLFKSIEEKKHASIKNGLPSPDFKVNAQFLELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSAGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHLSQTRMCPQIDTENAIDNKVISESSQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRNEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRTRITQLVSDQANQVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARSPYFSGSSAFSPTIMSSDKETIEIIDLAKKDLEKLKRKEKKKKKSVAGKEDNIDTDQEKKEEKGISERENNELEVEESQEVSDHEDEEEEEEEEEDDIEGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKIRSEYEKKLQAMNKELQRLQTAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLMESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPVQDTGSSAAAIETDASRAGAQQKMRIPVARVQALPAPITNGTRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVVNINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQIEITSATQNQLLFHMLKEKAELNPELDALLGHALQENVEDSTDEDVPLNSPGSEGSSLSSDLMKLCGEVKPKSKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSTSAREKDLPPPSGFPSKIGSISRQSSLSEKKLPEPSPITRRKVYEKAEKAKAKEQKQGIINPFPPSKGIRASPLQCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSTSTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIRMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWICALGVVPAHPVLLSGCRGGILKLWNMDNFVPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKTRNLQDGQISDTGDLGEDIASN", "length": 1593, "header": "tr|A0A5G2QNI7-1|A0A5G2QNI7_PIG Computationally mapped isoform of Kinesin family member 21A OS=Sus scrofa OX=9823 GN=KIF21A PE=1 SV=2 CANONICAL=A0A5G2RBR1-1" }, "locus": { "chromosome": "5", "start_pos": 71029352, "end_pos": 70890678, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071566.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071566.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065615.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065615.2" } ] } }, { "isoform_ac": "A0A5G2RBR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1/entry#A0A5G2RBR1-1", "sequence": { "sequence": "MWGAPDESSVRVAVRIRPQLAKERIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIIEEEQGIISRAVKHLFKSIEEKKHASIKNGLPSPDFKVNAQFLELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSAGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHLSQTRMCPQIDTENAIDNKVISESSQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRNEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRTRITQLVSDQANQVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARSPYFSGSSAFSPTIMSSDKETIEIIDLAKKDLEKLKRKEKKKKKRLQKLEESNREERSVAGKEDNIDTDQEKKEEKGISERENNELEVEESQEVSDHEDEEEEEEEEEDDIEGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKIRSEYEKKLQAMNKELQRLQTAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLMESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPVQDTGSSAAAIETDASRAGAQQKMRIPVARVQALPAPITNGTRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVVNINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQIEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDVPLNSPGSEGSSLSSDLMKLCGEVKPKSKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSTSAREKDLPPPSGFPSKIGSISRQSSLSEKKLPEPSPITRRKVYEKAEKAKAKEQKHSDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRGIINPFPPSKGIRASPLQCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSTSTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIRMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWICALGVVPAHPVLLSGCRGGILKLWNMDNFVPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKTRNLQDGQISDTGDLGEDIASN", "length": 1669, "header": "tr|A0A5G2RBR1-1|A0A5G2RBR1_PIG Isoform 1 of Kinesin-like protein KIF21A OS=Sus scrofa OX=9823 GN=KIF21A PE=1 SV=2 CANONICAL=A0A5G2RBR1-1" }, "locus": { "chromosome": "5", "start_pos": 71029352, "end_pos": 70890678, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086842.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086842.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073785.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073785.2" } ] } }, { "isoform_ac": "A0A8W4FKT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1/entry#A0A8W4FKT7-1", "sequence": { "sequence": "MWGAPDESSVRVAVRIRPQLAKERIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIIEEEQGIISRAVKHLFKSIEEKKHASIKNGLPSPDFKVNAQFLELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSAGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHLSQTRMCPQIDTENAIDNKVISESSQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRNEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRTRITQLVSDQANQVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARSPYFSGSSAFSPTIMSSDKETIEIIDLAKKDLEKLKRKEKKKKKSVAGKEDNIDTDQEKKEEKGISERENNELEVEESQEVSDHEDEEEEEEEEEDDIEGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKIRSEYEKKLQAMNKELQRLQTAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLMESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPVQDTGSSAAAIETDASRAGAQQKMRIPVARVQALPAPITNGTRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVVNINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQIEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDVPLNSPGSEGSSLSSDLMKLCGEVKPKSKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSTSAREKDLPPPSGFPSKIGSISRQSSLSEKKLPEPSPITRRKVYEKAEKAKAKEQKQSDESDSSLSEVHSRSSRRGIINPFPPSKGIRASPLQCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSTSTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIRMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWICALGVVPAHPVLLSGCRGGILKLWNMDNFVPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKTRNLQDGQISDTGDLGEDIASN", "length": 1618, "header": "tr|A0A8W4FKT7-1|A0A5G2RBR1_PIG Computationally mapped isoform of Kinesin-like protein KIF21A OS=Sus scrofa OX=9823 GN=KIF21A PE=1 SV=1 CANONICAL=A0A5G2RBR1-1" }, "locus": { "chromosome": "5", "start_pos": 71029352, "end_pos": 70890678, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093416.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093416.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079522.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079522.1" } ] } }, { "isoform_ac": "F1SHQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1/entry#F1SHQ3-1", "sequence": { "sequence": "MWGAPDESSVRVAVRIRPQLAKERIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIIEEEQGIISRAVKHLFKSIEEKKHASIKNGLPSPDFKVNAQFLELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSAGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHLSQTRMCPQIDTENAIDNKVISESSQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRNEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRTRITQLVSDQANQVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARSPYFSGSSAFSPTIMSSDKETIEIIDLAKKDLEKLKRKEKKKKKSVAGKEDNIDTDQEKKEEKGISERENNELEVEESQEVSDHEDEEEEEEEEEDDIEGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKIRSEYEKKLQAMNKELQRLQTAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLMESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPVQDTGSSAAAIETDASRAGAQQKMRIPVARVQALPAPITNGTRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVVNINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQIEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDVPLNSPGSEGSSLSSDLMKLCGEVKPKSKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSTSAREKDLPPPSGFPSKIGSISRQSSLSEKKLPEPSPITRRKVYEKAEKAKAKEQKHSDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHSRSSRRGIINPFPPSKGIRASPLQCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSTSTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIRMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWICALGVVPAHPVLLSGCRGGILKLWNMDNFVPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKTRNLQDGQISDTGDLGEDIASN", "length": 1661, "header": "tr|F1SHQ3-1|F1SHQ3_PIG Computationally mapped isoform of Kinesin-like protein KIF21A OS=Sus scrofa OX=9823 GN=KIF21A PE=1 SV=5 CANONICAL=A0A5G2RBR1-1" }, "locus": { "chromosome": "5", "start_pos": 71029352, "end_pos": 70890678, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000843.5", "url": "https://www.ensembl.org/id/ENSSSCT00000000843.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000826.5", "url": "https://www.ensembl.org/id/ENSSSCP00000000826.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FKT7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKT7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-SSC-983189", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983189", "resource": "Reactome", "description": "Kinesins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "ankyrin repeat binding", "id": "GO:0071532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071532", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "axonal growth cone", "id": "GO:0044295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044295", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "regulation of axon guidance", "id": "GO:1902667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902667", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "regulation of microtubule polymerization", "id": "GO:0031113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031113", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "cortical microtubule organization", "id": "GO:0043622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043622", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" }, { "name": "regulation of microtubule depolymerization", "id": "GO:0031114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031114", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1000, "end_pos": 1002, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1295, "end_pos": 1297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1392, "end_pos": 1394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1630, "end_pos": 1632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" }, { "start_pos": 898, "end_pos": 900, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RBR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR1" }, { "id": "PS50067", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kinesin motor", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 371, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 35 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1000, "end_pos": 1002 }, { "start_pos": 1295, "end_pos": 1297 }, { "start_pos": 1392, "end_pos": 1394 }, { "start_pos": 1630, "end_pos": 1632 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 649, "end_pos": 651 }, { "start_pos": 748, "end_pos": 750 }, { "start_pos": 81, "end_pos": 83 }, { "start_pos": 898, "end_pos": 900 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RGN2-1", "uniprot_ac": "A0A5G2RGN2", "uniprot_id": "A0A5G2RGN2_PIG", "mass": { "chemical_mass": 49402.0, "monoisotopic_mass": 49402.0 }, "refseq": {}, "gene_names": [ { "name": "SCLY", "type": "recommended", "evidence": [ { "id": "A0A5G2RGN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2" } ] } ], "protein_names": [ { "name": "Selenocysteine lyase", "type": "recommended", "evidence": [ { "id": "A0A5G2RGN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2/entry#names_and_taxonomy" } ] }, { "name": "4.4.1.16", "type": "synonym", "evidence": [ { "id": "A0A5G2RGN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QFT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFT9#function" }, { "database": "UniProtKB", "id": "ARBA00037407", "url": "https://www.uniprot.org/uniprotkb/ARBA00037407#function" }, { "database": "UniProtKB", "id": "A0A5G2QTL9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTL9#function" }, { "database": "UniProtKB", "id": "A0A287AJF7", "url": "https://www.uniprot.org/uniprotkb/A0A287AJF7#function" }, { "database": "UniProtKB", "id": "A0A5G2RGN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2#function" }, { "database": "UniProtKB", "id": "F1SJI1", "url": "https://www.uniprot.org/uniprotkb/F1SJI1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SCLY", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2", "locus": { "chromosome": "15", "start_pos": 137674735, "end_pos": 137637128, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016334", "url": "https://www.ensembl.org/id/ENSSSCG00000016334" } ] } } ], "crossref": [ { "id": "A0A5G2RGN2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016334", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016334", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100294677", "url": "https://www.ncbi.nlm.nih.gov/gene/100294677", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11601", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11601", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11601:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11601:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2408508", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2408508", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AJF7", "url": "https://www.uniprot.org/uniprotkb/A0A287AJF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AJF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTL9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJI1", "url": "https://www.uniprot.org/uniprotkb/F1SJI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJI1-1", "url": "https://www.uniprot.org/uniprotkb/F1SJI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PGCGGVRMEAAGKRSRDERGRAASVPDGHAEKSLLDRKVYMDYNATTPLEPEVIQAMAEAMQEAWGNPSSSYPEGRKAKETIGAARESLARMVGGRPQDVIFTSGGTESNNLVIHSALKHFHKTHISEGDAAEHPRPVAGALPHFITCTVEHDSIRLPLEHLVEEREAEVTFVPVSKVSGQVKAEDILAAVRPTTCLVTIMLANNETGVVMPVPDISRRVRALNQQRAARGLPVLLLHTDAAQALGKRRVDVWDLGVDFLTIVGHKFYGPRIGALYVRGLGELTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVAENCEAYEAHMETVRDYLEERLAAEFGKRIHLNSQFPGTERLPNTCNFSILGPQLQGDDRLPLALARVVGLVGWAGHGACRQEAGRGPSPVLLSFGIPLDVARNAIRLSVGRSTTRAEVDLVVQDLKQAVARLEGQA", "length": 456, "header": "tr|A0A5G2RGN2-1|A0A5G2RGN2_PIG Isoform 1 of Selenocysteine lyase OS=Sus scrofa OX=9823 GN=SCLY PE=1 SV=2 CANONICAL=A0A5G2RGN2-1" }, "isoforms": [ { "isoform_ac": "A0A287AJF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2/entry#A0A287AJF7-1", "sequence": { "sequence": "MEAAGKRSRDERGRAASVPDGHAEKSLLDRKVYMDYNATTPLEPEVIQAMAEAMQEAWGNPSSSYPEEVTFVPVSKVSGQVKAEDILAAVRPTTCLVTIMLANNETGVVMPVPDISRRVRALNQQRAARGLPVLLLHTDAAQALGKRRVDVWDLGVDFLTIVGHKFYGPRIGALYVRGLGELTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVAENCEAYEAHMETVRDYLEERLAAEFGKRIHLNSQFPGTERLPNTCNFSILGPQLQGRSVLAQCRTLVASVGAACHSDLGDRPSPVLLSFGIPLDVARNAIRLSVGRSTTRAEVDLVVQDLKQAVARLEGQA", "length": 350, "header": "tr|A0A287AJF7-1|A0A5G2RGN2_PIG Computationally mapped isoform of Selenocysteine lyase OS=Sus scrofa OX=9823 GN=SCLY PE=1 SV=1 CANONICAL=A0A5G2RGN2-1" }, "locus": { "chromosome": "15", "start_pos": 137673897, "end_pos": 137637237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055111.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055111.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044145.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044145.1" } ] } }, { "isoform_ac": "A0A5G2QFT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2/entry#A0A5G2QFT9-1", "sequence": { "sequence": "MDARTRGVAWEGLLGRKVYMDYNATTPLEPEVIQAMAEAMQEAWGNPSSSYPEGRKAKETIGAARESLARMVGGRPQDVIFTSGGTESNNLVIHSALKHFHKTHISEGDAAEHPRPVAGALPHFITCTVEHDSIRLPLEHLVEEREAEVTFVPVSKVSGQVKAEDILAAVRPTTCLVTIMLANNETGVVMPVPDISRRVRALNQQRAARGLPVLLLHTDAAQALGKRRVDVWDLGVDFLTIVGHKFYGPRIGALYVRGLGELTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVAENCEAYEAHMETVRDYLEERLAAEFGKRIHLNSQFPGTERLPNTCNFSILGPQLQGRSVLAQCRTLVASVGAACHSDLGDRPSPVLLSFGIPLDVARNAIRLSVGRSTTRAEVDLVVQDLKQAVARLEGQA", "length": 430, "header": "tr|A0A5G2QFT9-1|A0A5G2RGN2_PIG Computationally mapped isoform of Selenocysteine lyase OS=Sus scrofa OX=9823 GN=SCLY PE=1 SV=1 CANONICAL=A0A5G2RGN2-1" }, "locus": { "chromosome": "15", "start_pos": 137673897, "end_pos": 137637598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067989.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067989.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063097.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063097.1" } ] } }, { "isoform_ac": "A0A5G2QTL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2/entry#A0A5G2QTL9-1", "sequence": { "sequence": "MDYNATTPLEPEVIQAMAEAMQEAWGNPSSSYPEGRKAKETIGAARESLARMVGGRPQDVIFTSGGTESNNLVIHSALKHFHKTHISEGDAAEHPRPVAGALPHFITCTVEHDSIRLPLEHLVEEREAEVTFVPVSKVSGQVKAEDILAAVRPTTCLVTIMLANNETGVVMPVPDISRRVRALNQQRAARGLPVLLLHTDAAQALGKRRVDVWDLGVDFLTIVGHKFYGPRIGALYVRGLGELTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVAENCEAYEAHMETVRDYLEERLAAEFGKRIHLNSQFPGTERLPNTCNFSILGPQLQGRSVLAQCRTLVASVGAACHSDLGDRPSPVLLSFGIPLDVARNAIRLSVGRSTTRAEVDLVVQDLKQAVARLEGQA", "length": 411, "header": "tr|A0A5G2QTL9-1|A0A5G2RGN2_PIG Computationally mapped isoform of Selenocysteine lyase OS=Sus scrofa OX=9823 GN=SCLY PE=1 SV=1 CANONICAL=A0A5G2RGN2-1" }, "locus": { "chromosome": "15", "start_pos": 137673897, "end_pos": 137641324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087613.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087613.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067497.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067497.1" } ] } }, { "isoform_ac": "A0A5G2RGN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2/entry#A0A5G2RGN2-1", "sequence": { "sequence": "PGCGGVRMEAAGKRSRDERGRAASVPDGHAEKSLLDRKVYMDYNATTPLEPEVIQAMAEAMQEAWGNPSSSYPEGRKAKETIGAARESLARMVGGRPQDVIFTSGGTESNNLVIHSALKHFHKTHISEGDAAEHPRPVAGALPHFITCTVEHDSIRLPLEHLVEEREAEVTFVPVSKVSGQVKAEDILAAVRPTTCLVTIMLANNETGVVMPVPDISRRVRALNQQRAARGLPVLLLHTDAAQALGKRRVDVWDLGVDFLTIVGHKFYGPRIGALYVRGLGELTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVAENCEAYEAHMETVRDYLEERLAAEFGKRIHLNSQFPGTERLPNTCNFSILGPQLQGDDRLPLALARVVGLVGWAGHGACRQEAGRGPSPVLLSFGIPLDVARNAIRLSVGRSTTRAEVDLVVQDLKQAVARLEGQA", "length": 456, "header": "tr|A0A5G2RGN2-1|A0A5G2RGN2_PIG Isoform 1 of Selenocysteine lyase OS=Sus scrofa OX=9823 GN=SCLY PE=1 SV=2 CANONICAL=A0A5G2RGN2-1" }, "locus": { "chromosome": "15", "start_pos": 137673897, "end_pos": 137637216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083635.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083635.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070394.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070394.2" } ] } }, { "isoform_ac": "F1SJI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2/entry#F1SJI1-1", "sequence": { "sequence": "PGCGGVRMEAAGKRSRDERGRAASVPDGHAEKSLLDRKVYMDYNATTPLEPEVIQAMAEAMQEAWGNPSSSYPEGRKAKETIGAARESLARMVGGRPQDVIFTSGGTESNNLVIHSALKHFHKTHISEGDAAEHPRPVAGALPHFITCTVEHDSIRLPLEHLVEEREAEVTFVPVSKVSGQVKAEDILAAVRPTTCLVTIMLANNETGVVMPVPDISRRVRALNQQRAARGLPVLLLHTDAAQALGKRRVDVWDLGVDFLTIVGHKFYGPRIGALYVRGLGELTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVAENCEAYEAHMETVRDYLEERLAAEFGKRIHLNSQFPGTERLPNTCNFSILGPQLQGRSVLAQCRTLVASVGAACHSDLGDRPSPVLLSFGIPLDVARNAIRLSVGRSTTRAEVDLVVQDLKQAVARLEGQA", "length": 451, "header": "tr|F1SJI1-1|F1SJI1_PIG Computationally mapped isoform of Selenocysteine lyase OS=Sus scrofa OX=9823 GN=SCLY PE=1 SV=4 CANONICAL=A0A5G2RGN2-1" }, "locus": { "chromosome": "15", "start_pos": 137673897, "end_pos": 137637216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017787.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017787.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017306.4", "url": "https://www.ensembl.org/id/ENSSSCP00000017306.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QFT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFT9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2408508", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2408508", "resource": "Reactome", "description": "Metabolism of ingested SeMet, Sec, MeSec into H2Se" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2" } ], "pmid": "" }, { "name": "selenocysteine lyase activity", "id": "GO:0009000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009000", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-2408524", "name": "Sec is reduced to H2Se by PXLP-K259-SCLY dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-5357697" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2408524", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2408524" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5357697", "participant_name": "Sec [cytosol]", "crossref": [ { "id": "57843", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RGN2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 456, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RGN2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGN2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RGN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGN2" }, { "id": "PF00266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminotransferase class V", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 440, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 366, "end_pos": 368 }, { "start_pos": 44, "end_pos": 46 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAI2-1", "uniprot_ac": "A0A5G2RAI2", "uniprot_id": "A0A5G2RAI2_PIG", "mass": { "chemical_mass": 73414.0, "monoisotopic_mass": 73414.0 }, "refseq": {}, "gene_names": [ { "name": "UBP1", "type": "recommended", "evidence": [ { "id": "A0A5G2RAI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2" } ] } ], "protein_names": [ { "name": "Upstream-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2RAI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UBP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2", "locus": { "chromosome": "13", "start_pos": 19203954, "end_pos": 19276637, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011235", "url": "https://www.ensembl.org/id/ENSSSCG00000011235" } ] } } ], "crossref": [ { "id": "A0A5G2RAI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011235", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011235", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11037:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11037:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AKT2", "url": "https://www.uniprot.org/uniprotkb/A0A287AKT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AKT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AKT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGNGRPFWPRLFLGVVCREAARPRGLGTCGVGGAVLRGATVPPPLSSGSAAKSPAVRGGPEPRASAGAGARPGWGRRRRKRGASSSRSHSEASIWADGAASAGTRPRSSGLFAPLAEAALRAGRRRGRKMAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDDETKHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKIGDVPEITGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAHEKEKYQPSYDTTVLTEMRLEPIIEDAVEHEQKKSSKRTLPADYGDSLAKRGSCSPWPDTPTTYVNHSPSPAPTFSSPPQSTCSVPDSNSSSPNHQGDGVSQASSEQLQPSATIQETQQWLLKNRFSSYTRLFSNFLGADLLKLTKEDLVQICGTADGIRLYHSLKSRSVRPRLTLYVCREQPVQQGQQQAAGGGGDSSSATPYVYHAIYLEEMVASEVARKLALVFNIPLHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAENGGGVHIILK", "length": 667, "header": "tr|A0A5G2RAI2-1|A0A5G2RAI2_PIG Isoform 1 of Upstream-binding protein 1 OS=Sus scrofa OX=9823 GN=UBP1 PE=1 SV=1 CANONICAL=A0A5G2RAI2-1" }, "isoforms": [ { "isoform_ac": "A0A287AKT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2/entry#A0A287AKT2-1", "sequence": { "sequence": "MGGNGRPFWPRLFLGVVCREAARPRGLGTCGVGGAVLRGATVPPPLSSGSAAKSPAVRGGPEPRASAGAGARPGWGRRRRKRGASSSRSHSEASIWADGAASAGTRPRSSGLFAPLAEAALRAGRRRGRKMAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDDETKHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKIGDVPEITGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAHEKEKYQPSYDTTVLTECSPWPDTPTTYVNHSPSPAPTFSSPPQSTCSVPDSNSSSPNHQGDGVSQASSEQLQPSATIQETQQWLLKNRFSSYTRLFSNFLGADLLKLTKEDLVQICGTADGIRLYHSLKSRSVRPRLTLYVCREQPVQQGQQQAAGGGGDSSSATPYVYHAIYLEEMVASEVARKLALVFNIPLHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAENGGGVHIILK", "length": 631, "header": "tr|A0A287AKT2-1|A0A5G2RAI2_PIG Computationally mapped isoform of Upstream-binding protein 1 OS=Sus scrofa OX=9823 GN=UBP1 PE=1 SV=2 CANONICAL=A0A5G2RAI2-1" }, "locus": { "chromosome": "13", "start_pos": 19276637, "end_pos": 19206841, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050090.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050090.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044508.2", "url": "https://www.ensembl.org/id/ENSSSCP00000044508.2" } ] } }, { "isoform_ac": "A0A5G2RAI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2/entry#A0A5G2RAI2-1", "sequence": { "sequence": "MGGNGRPFWPRLFLGVVCREAARPRGLGTCGVGGAVLRGATVPPPLSSGSAAKSPAVRGGPEPRASAGAGARPGWGRRRRKRGASSSRSHSEASIWADGAASAGTRPRSSGLFAPLAEAALRAGRRRGRKMAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDDETKHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKIGDVPEITGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAHEKEKYQPSYDTTVLTEMRLEPIIEDAVEHEQKKSSKRTLPADYGDSLAKRGSCSPWPDTPTTYVNHSPSPAPTFSSPPQSTCSVPDSNSSSPNHQGDGVSQASSEQLQPSATIQETQQWLLKNRFSSYTRLFSNFLGADLLKLTKEDLVQICGTADGIRLYHSLKSRSVRPRLTLYVCREQPVQQGQQQAAGGGGDSSSATPYVYHAIYLEEMVASEVARKLALVFNIPLHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAENGGGVHIILK", "length": 667, "header": "tr|A0A5G2RAI2-1|A0A5G2RAI2_PIG Isoform 1 of Upstream-binding protein 1 OS=Sus scrofa OX=9823 GN=UBP1 PE=1 SV=1 CANONICAL=A0A5G2RAI2-1" }, "locus": { "chromosome": "13", "start_pos": 19276637, "end_pos": 19206841, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077497.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077497.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074334.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074334.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AKT2", "url": "https://www.uniprot.org/uniprotkb/A0A287AKT2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2" } ], "pmid": "" }, { "name": "negative regulation of viral transcription", "id": "GO:0032897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 475, "end_pos": 477, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAI2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 667, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAI2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAI2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI2" }, { "id": "PS51968", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51968" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Grh/CP2 DB", "eco_id": "ECO_0000259", "start_pos": 190, "end_pos": 426, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 452, "end_pos": 454 }, { "start_pos": 475, "end_pos": 477 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2REA5-1", "uniprot_ac": "A0A5G2REA5", "uniprot_id": "A0A5G2REA5_PIG", "mass": { "chemical_mass": 61364.0, "monoisotopic_mass": 61364.0 }, "refseq": { "ac": "XP_020938567", "name": "solute carrier family 22 member 9-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938567" }, "gene_names": [ { "name": "LOC110255291", "type": "recommended", "evidence": [ { "id": "A0A5G2REA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5" } ] }, { "name": "LOC110255291", "type": "synonym", "evidence": [ { "id": "XP_020938567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938567" } ] } ], "protein_names": [ { "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2REA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 22 member 9-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020938567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938567" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110255291", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5", "locus": {} } ], "crossref": [ { "id": "A0A5G2REA5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2REA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013057", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013057", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17374", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110255291", "url": "https://www.ncbi.nlm.nih.gov/gene/110255291", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110255291", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255291", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLKYVMD", "url": "https://omabrowser.org/oma/group/YLKYVMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2REA5", "url": "https://www.orthodb.org/?gene=A0A5G2REA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020938567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938567", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287ALC8", "url": "https://www.uniprot.org/uniprotkb/A0A287ALC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ALC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ALC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LPA0", "url": "https://www.uniprot.org/uniprotkb/I3LPA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LPA0-1", "url": "https://www.uniprot.org/uniprotkb/I3LPA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFHELLDKAGGLGRFQILQMVFLCISSFLVQPHVLLENFTAAVPGHRCWVHILDNDTDSANSTGTLSQDALLRISIPLDSNLKPEKCRRFLHPQWQLLHLNETFPNVTDLDTEPCVDGWVYDRSAFSSTIVTEWDVVCESQSLNSVSKFLFMAGMLVGNFIYGQLSDRFGRRLVIILCFLQLGIADTTTVIAPNFLIYCSLRFLAGISTSPLLTNSFVLMLEWTVPQFQTLVVALLLTSTTLGQLILGGLAFAIRDWRTLQLVVSIPIFVLFLASRWLVESARWLLVTNKPKEGLKELRKAAHRNGKKNVNDTLTMEIMRATMQEELEAAQTKTSVFDLFRTPNMRKRTCAMSFMRFANTMTYFALSLHLQHLGSNIFLLQVFFGLINIPANYCAFLALNHLGRRGSQMLFLFLLSSLVIAITSVPQEMQAVRMVLASLAAGSCSALFSCFVSHSAELIPTVLRSTSSGVLGIAGGSGAALSPLLMILTVYSPPLPWIICGIFSLLAGFAVLLLPETKNQPLPDSIQDVENKGNDSRKTEQEDSFMKVTQF", "length": 552, "header": "tr|A0A5G2REA5-1|A0A5G2REA5_PIG Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110255291 PE=4 SV=1 CANONICAL=A0A5G2REA5-1" }, "isoforms": [ { "isoform_ac": "A0A287ALC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5/entry#A0A287ALC8-1", "sequence": { "sequence": "MAFHELLDKAGGLGRFQILQMVFLCISSFLVQPHVLLENFTAAVPGHRCWVHILDNDTDSANSTGTLSQDALLRISIPLDSNLKPEKCRRFLHPQWQLLHLNETFPNVTDLDTEPCVDGWVYDRSAFSSTIVTEWDVVCESQSLNSVSKFLFMAGMLVGNFIYGQLSDRFGRRLVIILCFLQLGIADTTTVIAPNFLIYCSLRFLAGISTSPLLTNSFVLMLEWTVPQFQTLVVALLLTSTTLGQLILGGLAFAIRDWRTLQLVVSIPIFVLFLASRWLVESARWLLVTNKPKEGLKELRKAAHRNGKKNVNDTLTMEHLGSNIFLLQVFFGLINIPANYCAFLALNHLGRRGSQMLFLFLLSSLVIAITSVPQEMQAVRMVLASLAAGSCSALFSCFVSHSAELIPTVLRSTSSGVLGIAGGSGAALSPLLMILTVYSPPLPWIICGIFSLLAGFAVLLLPETKNQPLPDSIQDVENKGNDSRKTEQEDSFMKVTQF", "length": 498, "header": "tr|A0A287ALC8-1|A0A5G2REA5_PIG Computationally mapped isoform of Major facilitator superfamily (MFS) profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110255291 PE=4 SV=2 CANONICAL=A0A5G2REA5-1" }, "locus": { "chromosome": "2", "start_pos": 8574372, "end_pos": 8548790, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045832.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045832.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044806.2", "url": "https://www.ensembl.org/id/ENSSSCP00000044806.2" } ] } }, { "isoform_ac": "A0A5G2REA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5/entry#A0A5G2REA5-1", "sequence": { "sequence": "MAFHELLDKAGGLGRFQILQMVFLCISSFLVQPHVLLENFTAAVPGHRCWVHILDNDTDSANSTGTLSQDALLRISIPLDSNLKPEKCRRFLHPQWQLLHLNETFPNVTDLDTEPCVDGWVYDRSAFSSTIVTEWDVVCESQSLNSVSKFLFMAGMLVGNFIYGQLSDRFGRRLVIILCFLQLGIADTTTVIAPNFLIYCSLRFLAGISTSPLLTNSFVLMLEWTVPQFQTLVVALLLTSTTLGQLILGGLAFAIRDWRTLQLVVSIPIFVLFLASRWLVESARWLLVTNKPKEGLKELRKAAHRNGKKNVNDTLTMEIMRATMQEELEAAQTKTSVFDLFRTPNMRKRTCAMSFMRFANTMTYFALSLHLQHLGSNIFLLQVFFGLINIPANYCAFLALNHLGRRGSQMLFLFLLSSLVIAITSVPQEMQAVRMVLASLAAGSCSALFSCFVSHSAELIPTVLRSTSSGVLGIAGGSGAALSPLLMILTVYSPPLPWIICGIFSLLAGFAVLLLPETKNQPLPDSIQDVENKGNDSRKTEQEDSFMKVTQF", "length": 552, "header": "tr|A0A5G2REA5-1|A0A5G2REA5_PIG Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110255291 PE=4 SV=1 CANONICAL=A0A5G2REA5-1" }, "locus": { "chromosome": "2", "start_pos": 8574372, "end_pos": 8548790, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090981.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090981.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072931.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072931.1" } ] } }, { "isoform_ac": "I3LPA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5/entry#I3LPA0-1", "sequence": { "sequence": "MAFHELLDKAGGLGRFQILQMVFLCISSFLVQPHVLLENFTAAVPGHRCWVHILDNDTDSANSTGTLSQDALLRISIPLDSNLKPEKCRRFLHPQWQLLHLNETFPNVTDLDTEPCVDGWVYDRSAFSSTIVTEWDVVCESQSLNSVSKFLFMAGMLVGNFIYGQLSDRFGRRLVIILCFLQLGIADTTTVIAPNFLIYCSLRFLAGISTSPLLTNSFVLMLEWTVPQFQTLVVALLLHHSGTILGGLAFAIRDWRTLQLVVSIPIFVLFLASRWLVESARWLLVTNKPKEGLKELRKAAHRNGKKNVNDTLTMEIMRATMQEELEAAQTKTSVFDLFRTPNMRKRTCAMSFMRFLVSIPVFALVLHLQLLGENVFLLQILFGIINTPSNWVAFLALNHLGRRVSQILFTFLQAVFILVLAFIPQEMQTVRAVLASLAAGFSSATFTSSVSHAFELIPTTIRATSTGVLGIAGGTGAALSPLLMILTVYSPPLPWIVCGIFSLLAGFAVLLLPETKNQPLPDSIQDVENKRKDSIKEGQEDTFMKVTQF", "length": 549, "header": "tr|I3LPA0-1|A0A5G2REA5_PIG Computationally mapped isoform of Major facilitator superfamily (MFS) profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC110255291 PE=4 SV=4 CANONICAL=A0A5G2REA5-1" }, "locus": { "chromosome": "2", "start_pos": 8574372, "end_pos": 8512865, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028828.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028828.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025926.4", "url": "https://www.ensembl.org/id/ENSSSCP00000025926.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LPA0", "url": "https://www.uniprot.org/uniprotkb/I3LPA0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110255291", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255291", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "organic anion transport", "id": "GO:0015711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015711", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2REA5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 552, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2REA5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2REA5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2REA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REA5" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 519, "start_aa": "Trp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 107, "end_pos": 109 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RBP0-1", "uniprot_ac": "A0A5G2RBP0", "uniprot_id": "A0A5G2RBP0_PIG", "mass": { "chemical_mass": 43405.0, "monoisotopic_mass": 43405.0 }, "refseq": { "ac": "XP_003131349", "name": "methyltransferase-like protein 2A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131349" }, "gene_names": [ { "name": "METTL2A", "type": "recommended", "evidence": [ { "id": "A0A5G2RBP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0" } ] }, { "name": "METTL2A", "type": "synonym", "evidence": [ { "id": "XP_003131349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131349" } ] } ], "protein_names": [ { "name": "tRNA N(3)-cytidine methyltransferase", "type": "recommended", "evidence": [ { "id": "A0A5G2RBP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.-", "type": "synonym", "evidence": [ { "id": "A0A5G2RBP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0/entry#names_and_taxonomy" } ] }, { "name": "methyltransferase-like protein 2A", "type": "synonym", "evidence": [ { "id": "XP_003131349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131349" } ] } ], "function": [ { "annotation": "S-adenosyl-L-methionine-dependent methyltransferase.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QL82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QL82#function" }, { "database": "UniProtKB", "id": "PIRNR037755", "url": "https://www.uniprot.org/uniprotkb/PIRNR037755#function" }, { "database": "UniProtKB", "id": "A0A5G2RBP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "METTL2A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0", "locus": {} } ], "crossref": [ { "id": "A0A5G2RBP0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000033421", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033421", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515752", "url": "https://www.ncbi.nlm.nih.gov/gene/100515752", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515752", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515752", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RBP0", "url": "https://www.orthodb.org/?gene=A0A5G2RBP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22809:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22809:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08242", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08242", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003131349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131349", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "50960", "url": "https://www.rhea-db.org/rhea/50960", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60912", "url": "https://www.rhea-db.org/rhea/60912", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AT43", "url": "https://www.uniprot.org/uniprotkb/A0A287AT43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AT43-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AT43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QL82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QL82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QL82-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QL82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGSYPEESHTAVGGKRQQFGSRFLSDPARVFHHNAWDNVEWSEEQAAAAERKVQENSSQRVCQEKQVDYEINANKYWNDFYKIHENGFFKDRHWLFTEFPELAPIQNQNHLKELLSEKKRSEVPECKSSEDGSGLKIEQQDCSSVSLGHKTQPTPVEENVTQKLSHLEICPAEFPGSSATYRILEVGCGVGNTVFPILQTNNDPRLFVYCCDFSSTAIELVQTNSAYDPSRCFAFVHDLCDEDKSYPVPEDSLNVIILIFVLSAIVPDKMQKAIDRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSENFYVRGDGTRVYFFTQDELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYRKPILSNTG", "length": 378, "header": "tr|A0A5G2RBP0-1|A0A5G2RBP0_PIG Isoform 1 of tRNA N(3)-cytidine methyltransferase OS=Sus scrofa OX=9823 GN=METTL2A PE=3 SV=1 CANONICAL=A0A5G2RBP0-1" }, "isoforms": [ { "isoform_ac": "A0A287AT43-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0/entry#A0A287AT43-1", "sequence": { "sequence": "MPGTMWSGRKSRPPRRKGKSRRTVASACARKSKLKKLGPRDIKCLAQRATHAAFGSSLSRGRIGAAAASLHHSSWQSWILNLLSEAKDQTRIFMHTNRVCYHWATTGTSKNCLLNTPYVSLSCTLSSNFFSSEVDYEINANKYWNDFYKIHENGFFKDRHWLFTEFPELAPIQNQNHLKELLSEKKRSEVPECKSSEDGSGLKIEQQDCSSVSLGHKTQPTPVEENVTQKLSHLEICPAEFPGSSATYRILEVGCGVGNTVFPILQTNNDPRLFVYCCDFSSTAIELVQTNSAYDPSRCFAFVHDLCDEDKSYPVPEDSLNVIILIFVLSAIVPDKMQKAIDRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSENFYVRGDGTRVYFFTQDELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYRKPILSNTG", "length": 444, "header": "tr|A0A287AT43-1|A0A5G2RBP0_PIG Computationally mapped isoform of tRNA N(3)-cytidine methyltransferase OS=Sus scrofa OX=9823 GN=METTL2A PE=3 SV=2 CANONICAL=A0A5G2RBP0-1" }, "locus": { "chromosome": "12", "start_pos": 16308410, "end_pos": 16292037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053147.2", "url": "https://www.ensembl.org/id/ENSSSCT00000053147.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047268.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047268.2" } ] } }, { "isoform_ac": "A0A5G2QL82-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0/entry#A0A5G2QL82-1", "sequence": { "sequence": "MPVDYEINANKYWNDFYKIHENGFFKDRHWLFTEFPELAPIQNQNHLKELLSEKKRSEVPECKSSEDGSGLKIEQQDCSSVSLGHKTQPTPVEENVTQKLSHLEICPAEFPGSSATYRILEVGCGVGNTVFPILQTNNDPRLFVYCCDFSSTAIELVQTNSAYDPSRCFAFVHDLCDEDKSYPVPEDSLNVIILIFVLSAIVPDKMQKAIDRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSENFYVRGDGTRVYFFTQDELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYRKPILSNTG", "length": 313, "header": "tr|A0A5G2QL82-1|A0A5G2QL82_PIG Computationally mapped isoform of tRNA N(3)-cytidine methyltransferase OS=Sus scrofa OX=9823 GN=METTL2A PE=3 SV=1 CANONICAL=A0A5G2RBP0-1" }, "locus": { "chromosome": "12", "start_pos": 16308410, "end_pos": 16292037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075080.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075080.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064780.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064780.1" } ] } }, { "isoform_ac": "A0A5G2RBP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0/entry#A0A5G2RBP0-1", "sequence": { "sequence": "MDGSYPEESHTAVGGKRQQFGSRFLSDPARVFHHNAWDNVEWSEEQAAAAERKVQENSSQRVCQEKQVDYEINANKYWNDFYKIHENGFFKDRHWLFTEFPELAPIQNQNHLKELLSEKKRSEVPECKSSEDGSGLKIEQQDCSSVSLGHKTQPTPVEENVTQKLSHLEICPAEFPGSSATYRILEVGCGVGNTVFPILQTNNDPRLFVYCCDFSSTAIELVQTNSAYDPSRCFAFVHDLCDEDKSYPVPEDSLNVIILIFVLSAIVPDKMQKAIDRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSENFYVRGDGTRVYFFTQDELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYRKPILSNTG", "length": 378, "header": "tr|A0A5G2RBP0-1|A0A5G2RBP0_PIG Isoform 1 of tRNA N(3)-cytidine methyltransferase OS=Sus scrofa OX=9823 GN=METTL2A PE=3 SV=1 CANONICAL=A0A5G2RBP0-1" }, "locus": { "chromosome": "12", "start_pos": 16308513, "end_pos": 16292037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079854.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079854.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073760.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073760.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AT43", "url": "https://www.uniprot.org/uniprotkb/A0A287AT43" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515752", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515752", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "tRNA (cytidine-3-)-methyltransferase activity", "id": "GO:0052735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052735", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0" } ], "pmid": "" }, { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "50960", "name": "", "equation": "cytidine(32) in tRNA(Thr) + S-adenosyl-L-methionine = N(3)-methylcytidine(32) in tRNA(Thr) + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "50960", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50960" } ] }, { "id": "60912", "name": "", "equation": "cytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-methionine = N(3)-methylcytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60912", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60912" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RBP0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 378, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RBP0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBP0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RBP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP0" }, { "id": "PF08242", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08242" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase type 12", "eco_id": "ECO_0000259", "start_pos": 185, "end_pos": 287, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R6I4-1", "uniprot_ac": "A0A5G2R6I4", "uniprot_id": "A0A5G2R6I4_PIG", "mass": { "chemical_mass": 27673.0, "monoisotopic_mass": 27673.0 }, "refseq": {}, "gene_names": [ { "name": "PMEPA1", "type": "recommended", "evidence": [ { "id": "A0A5G2R6I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4" } ] } ], "protein_names": [ { "name": "Prostate transmembrane protein, androgen induced 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R6I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6I4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PMEPA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4", "locus": { "chromosome": "17", "start_pos": 57999287, "end_pos": 58054118, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034259", "url": "https://www.ensembl.org/id/ENSSSCG00000034259" } ] } } ], "crossref": [ { "id": "A0A5G2R6I4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6I4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034259", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034259", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100144523", "url": "https://www.ncbi.nlm.nih.gov/gene/100144523", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR043445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100144523", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100144523", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GISAMCY", "url": "https://omabrowser.org/oma/group/GISAMCY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16514", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16514", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16514:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16514:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2173788", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2173788", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BBB7", "url": "https://www.uniprot.org/uniprotkb/A0A287BBB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BBB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BBB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6I4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELEFVEITIIVVVVMVMVVVITCLLSHYKLSARSFLGRHSQGRRREDALSSEGCLWPSESTVSGSGVPEPQVYAPPRPADRLAVPPFAQRDRFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLMDSAMLGGPCPPSSNSGISATCYGGGGRMEGPPPTYSEVIGHYPGASTFQHQQTSGPPSLLEGTRLHPAHIAPLESTAAWGKEKDKQKGHPL", "length": 253, "header": "tr|A0A5G2R6I4-1|A0A5G2R6I4_PIG Isoform 1 of Prostate transmembrane protein, androgen induced 1 OS=Sus scrofa OX=9823 GN=PMEPA1 PE=3 SV=1 CANONICAL=A0A5G2R6I4-1" }, "isoforms": [ { "isoform_ac": "A0A287BBB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4/entry#A0A287BBB7-1", "sequence": { "sequence": "MHRLMGVNSTAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVEITIIVVVVMVMVVVITCLLSHYKLSARSFLGRHSQGRRREDALSSEGCLWPSESTVSGSGVPEPQVYAPPRPADRLAVPPFAQRDRFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLMDSAMLGGPCPPSSNSGISATCYGGGGRMEGPPPTYSEVIGHYPGASTFQHQQTSGPPSLLEGTRLHPAHIAPLESTAAWGKEKDKQKGHPL", "length": 288, "header": "tr|A0A287BBB7-1|A0A5G2R6I4_PIG Computationally mapped isoform of Prostate transmembrane protein, androgen induced 1 OS=Sus scrofa OX=9823 GN=PMEPA1 PE=3 SV=1 CANONICAL=A0A5G2R6I4-1" }, "locus": { "chromosome": "17", "start_pos": 58053254, "end_pos": 58002832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048672.1", "url": "https://www.ensembl.org/id/ENSSSCT00000048672.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053357.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053357.1" } ] } }, { "isoform_ac": "A0A5G2R6I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4/entry#A0A5G2R6I4-1", "sequence": { "sequence": "MAELEFVEITIIVVVVMVMVVVITCLLSHYKLSARSFLGRHSQGRRREDALSSEGCLWPSESTVSGSGVPEPQVYAPPRPADRLAVPPFAQRDRFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLMDSAMLGGPCPPSSNSGISATCYGGGGRMEGPPPTYSEVIGHYPGASTFQHQQTSGPPSLLEGTRLHPAHIAPLESTAAWGKEKDKQKGHPL", "length": 253, "header": "tr|A0A5G2R6I4-1|A0A5G2R6I4_PIG Isoform 1 of Prostate transmembrane protein, androgen induced 1 OS=Sus scrofa OX=9823 GN=PMEPA1 PE=3 SV=1 CANONICAL=A0A5G2R6I4-1" }, "locus": { "chromosome": "17", "start_pos": 58054118, "end_pos": 58002832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067544.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067544.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069737.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069737.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BBB7", "url": "https://www.uniprot.org/uniprotkb/A0A287BBB7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100144523", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100144523", "resource": "KEGG Pathway" }, { "id": "R-SSC-2173788", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2173788", "resource": "Reactome", "description": "Downregulation of TGF-beta receptor signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "Q969W9-1", "protein_name": "Protein TMEPAI", "gene_name": "PMEPA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHRLMGVNSTAAAAAGQPNVSCTCNCKRSLFQSMEITELEFVQIIIIVVVMMVMVVVITCLLSHYKLSARSFISRHSQGRRREDALSSEGCLWPSESTVSGNGIPEPQVYAPPRPTDRLAVPPFAQRERFHRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLMDSARLGGPCPPSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQHQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL", "length": 287 }, "evidence": [ { "id": "A0A5G2R6I4", "url": "https://omabrowser.org/oma/group/A0A5G2R6I4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7R2-1", "protein_name": "Protein TMEPAI", "gene_name": "Pmepa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPARATAQRSLFPSMEITELEFVQIVVIVVVMMVMVVMITCLLSHYKLSARSFISRHSQARRRDDGLSSEGCLWPSESTVSGGMPEPQVYAPPRPTDRLAVPPFIQRSRFQPTYPYLQHEIALPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLIDSTMLGGPCPPSSNSGISATCYSSGGRMEGPPPTYSEVIGHYPGSSFQHQQSNGPSSLLEGTRLHHSHIAPLENKEKEKQKGHPL", "length": 260 }, "evidence": [ { "id": "A0A5G2R6I4", "url": "https://omabrowser.org/oma/group/A0A5G2R6I4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6I4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6I4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "WW domain binding", "id": "GO:0050699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050699", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6I4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4" } ], "pmid": "" }, { "name": "R-SMAD binding", "id": "GO:0070412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070412", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6I4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6I4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6I4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4" } ], "pmid": "" }, { "name": "negative regulation of SMAD protein signal transduction", "id": "GO:0060392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060392", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6I4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6I4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R6I4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 253, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R6I4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6I4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7P3-1", "uniprot_ac": "A0A5G2R7P3", "uniprot_id": "A0A5G2R7P3_PIG", "mass": { "chemical_mass": 195530.0, "monoisotopic_mass": 195530.0 }, "refseq": {}, "gene_names": [ { "name": "LTBP2", "type": "recommended", "evidence": [ { "id": "A0A5G2R7P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3" } ] } ], "protein_names": [ { "name": "Latent-transforming growth factor beta-binding protein 2", "type": "recommended", "evidence": [ { "id": "A0A5G2R7P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play an integral structural role in elastic-fiber architectural organization and/or assembly.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZZ4#function" }, { "database": "UniProtKB", "id": "ARBA00058734", "url": "https://www.uniprot.org/uniprotkb/ARBA00058734#function" }, { "database": "UniProtKB", "id": "A0A5G2R7P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3#function" }, { "database": "UniProtKB", "id": "F1S2T5", "url": "https://www.uniprot.org/uniprotkb/F1S2T5#function" }, { "database": "UniProtKB", "id": "A0A287BDJ6", "url": "https://www.uniprot.org/uniprotkb/A0A287BDJ6#function" }, { "database": "UniProtKB", "id": "A0A8W4FDF9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDF9#function" }, { "database": "UniProtKB", "id": "A0A5G2QAF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAF6#function" }, { "database": "UniProtKB", "id": "A0A5G2QLH2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLH2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LTBP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3", "locus": { "chromosome": "7", "start_pos": 97745396, "end_pos": 97852502, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002368", "url": "https://www.ensembl.org/id/ENSSSCG00000002368" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002368", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002368", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100514300", "url": "https://www.ncbi.nlm.nih.gov/gene/100514300", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514300", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514300", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FICTCKP", "url": "https://omabrowser.org/oma/group/FICTCKP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QZZ4", "url": "https://www.orthodb.org/?gene=A0A5G2QZZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1S2T5", "url": "https://www.orthodb.org/?gene=F1S2T5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24034:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24034:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00683", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00683", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287BDJ6", "url": "https://www.uniprot.org/uniprotkb/A0A287BDJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BDJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BDJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QAF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QAF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLH2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDF9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2T5", "url": "https://www.uniprot.org/uniprotkb/F1S2T5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2T5-1", "url": "https://www.uniprot.org/uniprotkb/F1S2T5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPSTTRRCPGRALRNPWRSFLPLTLALFVGLGHAQRDPVGRYEPAGRDANRLRRPGGSHPAAAAAKVYGLFRDQDASVPGLPPEERAQPGWGSARRPAETEARRPPRAQQPRRVQPPAQTWRSRSLSQQQPASRDRAAAALPRLGTVQRPRAARGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCQPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPEEEFDPQNSRPAPRRSAEGSPNLRRSSAARESSTARMRPPAPQPPPARTLSRLSQTHPSQQHMGLSQTVRLYPAAAASGQLTSNALPVGPGPERRDGAQQTAYVDHLSSPWGLNLTEKIKKIKIVFTPTICKQTCAHGRCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPAPRLDPEPPERGPRHRTPLEGSLKQSTFTLPLSNQLASVNPSLVKVHIHHPPEASVQVHQVARVRGEAEGAPEENSVETRPSPRFPTGPGHSPWSSNSIPTRSREAPRPPPPAVPRLRPLLGRCYLSAVNGQCANPLLELTAQEDCCGSVGAFWGVTSCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDVNECLTLGLCEDSECVNTRGSYLCTCRPGLLLDPSRSRCVSDKAVSMQQGLCYRLLGPGTCALPLAQRITKQICCCSRVGKAWGSKCETCPLPGTEAFREICPAGHGYTYSSSDIRLSMRKAEEEELARPSWEHVQKSHGTPPGPADRQPLRAATGTWLEAGTIPDKGDTQAGQVTTSVTQLATWVPGDAIGRPTPSLPARGIPEAQEEEQVTAPTDVLVTPAPPAIDRCATGATNICGPGTCVNLPDGYKCICSPGYRLHPSQAYCTDDNECLRDPCKGRGRCVNRVGSYSCFCYPGYMLATSGATQECQDIDECEQPGLCSGGRCTNTVGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLPCEEGYRGQSGSCVDVNECLTPGVCAHGTCLNLEGSFRCSCEPGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFTCSACESGYWVNEDGTACEDLDECAFPGVCPSGVCANTAGSFSCRDCEEGYRPSALGHTCEDVDECADPQSRCLGGECKNTAGSYQCLCPQGFQLTNGSVCEDVDECVGEEYCAPRGECLNSHGSFFCLCAPGFASADGGTSCQDVDECAVTDRCLRGQCVNTEGSFNCLCETGFQPSPESEECVDIDKCEDSGDSACGAWRCENSPGSHRCILGCQPGFHVAPAGDGIDIDECANDTVCGSHGYCDNTEGSFRCLCDQGFETSASGWDCVDVNECELMLAVCGTALCENVEGSFLCLCANDLEEYDAQEGHCRPRLAGGQSIPEASPGDRSPVPIRMECYSGQKGQPPCSSLLGRNTTQAECCCTQGTGWGDACDLCPAEDSVEFSEICPSGKGYVPVEGAWMFGQTTYTDADECVMFGHALCRNGRCLNTVPGYICLCNPGYHYDASRHKCEDHDECQDMACENGECVNTEGSFHCFCSPPLTLDLSQQRCVNSTSGLEDLPDHDIHTDICWKKVTNYVCSHPLHGRRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPEDLHYGLYGPEGAPFYNYLGPEDAIPEPLFPNTVSRPEDHTLVLEPPLQPSELQPHYVASHPENQAGFEGLQAEECGILNGCDNGRCVRVREGYTCDCFEGFQLDTAQMACVDVNECDDLNGPAALCVHGHCENTEGSYRCHCPPGYVAEAGPPHCTAKE", "length": 1814, "header": "tr|A0A5G2R7P3-1|A0A5G2R7P3_PIG Isoform 1 of Latent-transforming growth factor beta-binding protein 2 OS=Sus scrofa OX=9823 GN=LTBP2 PE=1 SV=1 CANONICAL=A0A5G2R7P3-1" }, "isoforms": [ { "isoform_ac": "A0A287BDJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3/entry#A0A287BDJ6-1", "sequence": { "sequence": "MRPSTTRRCPGRALRNPWRSFLPLTLALFVGLGHAQRDPVGRYEPAGRDANRLRRPGGSHPAAAAAKVYGLFRDQDASVPGLPPEERAQPGWGSARRPAETEARRPPRAQQPRRVQPPAQTWRSRSLSQQQPASRDRAAAALPRLGTVQRPRAARGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCQPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPEEEFDPQNSRPAPRRSAEGSPNLRRSSAARESSTARMRPPAPQPPPARTLSRLSQTHPSQQHMGLSQTVRLYPAAAASGQLTSNALPVGPGPERRDGAQQTAYVDHLSSPWGLNLTEKIKKIKIVFTPTICKQTCAHGRCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPAPRLDPEPPERGPRHRTPLEGSLKQSTFTLPLSNQLASVNPSLVKVHIHHPPEASVQVHQVARVRGEAEGAPEENSVETRPSPRFPTGPGHSPWSSNSIPTRSREAPRPPPPAVPRLRPLLGRCYLSAVNGQCANPLLELTAQEDCCGSVGAFWGVTSCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDVNECLTLGLCEDSECVNTRGSYLCTCRPGLLLDPSRSRCVSDKAVSMQQGLCYRLLGPGTCALPLAQRITKQICCCSRVGKAWGSKCETCPLPGTEAFREICPAGHGYTYSSSDIRLSMRKAEEEELARPSWEHVQKSHGTPPGPADRQPLRAATGTWLEAGTIPDKGDTQAGQVTTSVTQLATWVPGDAIGRPTPSLPARGIPEAQEEEQVTAPTDVLVTPAPPAIDRCATGATNICGPGTCVNLPDGYKCICSPGYRLHPSQAYCTDDNECLRDPCKGRGRCVNRVGSYSCFCYPGYMLATSGATQECQDIDECEQPGLCSGGRCTNTVGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLPCEEGYRGQSGSCVDVNECLTPGVCAHGTCLNLEGSFRCSCEPGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFTCSACESGYWVNEDGTACEDVDECADPQSRCLGGECKNTAGSYQCLCPQGFQLTNGSVCEDVDECVGEEYCAPRGECLNSHGSFFCLCAPGFASADGGTSCQDVDECAVTDRCLRGQCVNTEGSFNCLCETGFQPSPESEECVDIDECANDTVCGSHGYCDNTEGSFRCLCDQGFETSASGWDCVDVNECELMLAVCGTALCENVEGSFLCLCANDLEEYDAQEGHCRPRLAGGQSIPEASPGDRSPVPIRMECYSGQKGQPPCSSLLGRNTTQAECCCTQGTGWGDACDLCPAEDSVEFSEICPSGKGYVPVEGAWMFGQTTYTDADECVMFGHALCRNGRCLNTVPGYICLCNPGYHYDASRHKCEDHDECQDMACENGECVNTEGSFHCFCSPPLTLDLSQQRCVNSTSGLEDLPDHDIHTDICWKKVTNYVCSHPLHGRRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPEDLHYGLYGPEGAPFYNYLGPEDAIPEPLFPNTVSRPEDHTLVLEPPLQPSELQPHYVASHPENQAGFEGLQAEECGILNGCDNGRCVRVREGYTCDCFEGFQLDTAQMACVDVNECDDLNGPAALCVHGHCENTEGSYRCHCPPGYVAEAGPPHCTAKE", "length": 1728, "header": "tr|A0A287BDJ6-1|A0A5G2R7P3_PIG Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 2 OS=Sus scrofa OX=9823 GN=LTBP2 PE=1 SV=1 CANONICAL=A0A5G2R7P3-1" }, "locus": { "chromosome": "7", "start_pos": 97852097, "end_pos": 97748104, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052036.2", "url": "https://www.ensembl.org/id/ENSSSCT00000052036.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054597.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054597.1" } ] } }, { "isoform_ac": "A0A5G2QAF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3/entry#A0A5G2QAF6-1", "sequence": { "sequence": "MRPSTTRRCPGRALRNPWRSFLPLTLALFVGLGHAQRDPVGRYEPAGRDANRLRRPGGSHPAAAAAKVYGLFRDQDASVPGLPPEERAQPGWGSARRPAETEARRPPRAQQPRRVQPPAQTWRSRSLSQQQPASRDRAAAALPRLGTVQRPRAARGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCQPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPEEEFDPQNSRPAPRRSAEGSPNLRRSSAARESSTARMRPPAPQPPPARTLSRLSQTHPSQQHMGLSQTVRLYPAAAASGQLTSNALPVGPGPERRDGAQQTAYVDHLSSPWGLNLTEKIKKIKIVFTPTICKQTCAHGRCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPAPRLDPEPPERGPRHRTPLEGSLKQSTFTLPLSNQLAFWGVTSCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDVNECLTLGLCEDSECVNTRGSYLCTCRPGLLLDPSRSRCVSDKAVSMQQGLCYRLLGPGTCALPLAQRITKQICCCSRVGKAWGSKCETCPLPGTEAFREICPAGHGYTYSSSDIRLSMRKAEEEELARPSWEHVQKSHGTPPGPADRQPLRAATGTWLEAGTIPDKGDTQAGQVTTSVTQLATWVPGDAIGRPTPSLPARGIPEAQEEEQVTAPTDVLVTPAPPAIDRCATGATNICGPGTCVNLPDGYKCICSPGYRLHPSQAYCTDDNECLRDPCKGRGRCVNRVGSYSCFCYPGYMLATSGATQECQDIDECEQPGLCSGGRCTNTVGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLPCEEGYRGQSGSCVDVNECLTPGVCAHGTCLNLEGSFRCSCEPGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFTCSACESGYWVNEDGTACEDLDECAFPGVCPSGVCANTAGSFSCRDCEEGYRPSALGHTCEDVDECADPQSRCLGGECKNTAGSYQCLCPQGFQLTNGSVCEDVDECVGEEYCAPRGECLNSHGSFFCLCAPGFASADGGTSCQDVDECAVTDRCLRGQCVNTEGSFNCLCETGFQPSPESEECVDIDECANDTVCGSHGYCDNTEGSFRCLCDQGFETSASGWDCVDVNECELMLAVCGTALCENVEGSFLCLCANDLEEYDAQEGHCRPRLAGGQSIPEASPGDRSPVPIRMECYSGQKGQPPCSSLLGRNTTQAECCCTQGTGWGDACDLCPAEDSVEFSEICPSGKGYVPVEGAWMFGQTTYTDADECVMFGHALCRNGRCLNTVPGYICLCNPGYHYDASRHKCEDHDECQDMACENGECVNTEGSFHCFCSPPLTLDLSQQRCVNSTSGLEDLPDHDIHTDICWKKVTNYVCSHPLHGRRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPEDLHYGLYGPEGAPFYNYLGPEDAIPEPLFPNTVSRPEDHTLVLEPPLQPSELQPHYVASHPENQAGFEGLQAEECGILNGCDNGRCVRVREGYTCDCFEGFQLDTAQMACVDVNECDDLNGPAALCVHGHCENTEGSYRCHCPPGYVAEAGPPHCTAKE", "length": 1655, "header": "tr|A0A5G2QAF6-1|A0A5G2QAF6_PIG Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 2 OS=Sus scrofa OX=9823 GN=LTBP2 PE=1 SV=1 CANONICAL=A0A5G2R7P3-1" }, "locus": { "chromosome": "7", "start_pos": 97852097, "end_pos": 97748104, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073587.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073587.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061367.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061367.1" } ] } }, { "isoform_ac": "A0A5G2QLH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3/entry#A0A5G2QLH2-1", "sequence": { "sequence": "MRPSTTRRCPGRALRNPWRSFLPLTLALFVGLGHAQRDPVGRYEPAGRDANRLRRPGGSHPAAAAAKVYGLFRDQDASVPGLPPEERAQPGWGSARRPAETEARRPPRAQQPRRVQPPAQTWRSRSLSQQQPASRDRAAAALPRLGTVQRPRAARGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCQPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPEEEFDPQNSRPAPRRSAEGSPNLRRSSAARESSTARMRPPAPQPPPARTLSRLSQTHPSQQHMGLSQTVRLYPAAAASGQLTSNALPVGPGPERRDGAQQTAYVDHLSSPWGLNLTEKIKKIKIVFTPTICKQTCAHGRCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPAPRLDPEPPERGPRHRTPLEGSLKQSTFTLPLSNQLASVNPSLVKVHIHHPPEASVQVHQVARVRGEAEGAPEENSVETRPSPRFPTGPGHSPWSSNSIPTRSREAPRPPPPAVPRLRPLLGRCYLSAVNGQCANPLLELTAQEDCCGSVGAFWGVTSCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDVNECLTLGLCEDSECVNTRGSYLCTCRPGLLLDPSRSRCVSDKAVSMQQGLCYRLLGPGTCALPLAQRITKQICCCSRVGKAWGSKCETCPLPGTEAFREICPAGHGYTYSSSDIRLSMRKAEEEELARPSWEHVQKSHGTPPGPADRQPLRAATGTWLEAGTIPDKGIWGRWPSPLSYPPPGDAIGRPTPSLPARGIPEAQEEEQVTAPTDVLVTPAPPAIDRCATGATNICGPGTCVNLPDGYKCICSPGYRLHPSQAYCTDDNECLRDPCKGRGRCVNRVGSYSCFCYPGYMLATSGATQECQDIDECEQPGLCSGGRCTNTVGSYHCECDQGYIMQSSLQLLPFGPTSLTQWPVSDVDECASRASCPTGLCLNTEGSFTCSACESGYWVNEDGGPENAGLPTSQRHSICWASGPYEYLDECAFPGVCPSGVCANTAGSFSCRDCEEGYRPSALGHTCEDVDECADPQSRCLGGECKNTAGSYQCLCPQGFQLTNGSVCEDVDECVGEEYCAPRGECLNSHGSFFCLCAPGFASADGGTSCQDVDECAVTDRCLRGQCVNTEGSFNCLCETGFQPSPESEECVDIDKCEDSGDSACGAWRCENSPGSHRCILGCQPGFHVAPAGDGIDIDECANDTVCGSHGYCDNTEGSFRCLCDQGFETSASGWDCVDVNECELMLAVCGTALCENVEGSFLCLCANDLEEYDAQEGHCRPRLAGGQSIPEASPGDRSPVPIRMECYSGQKGQPPCSSLLGRNTTQAECCCTQGTGWGDACDLCPAEDSVEFSEICPSGKGYVPVEGAWMFGQTTYTDADECVMFGHALCRNGRCLNTVPGYICLCNPGYHYDASRHKCEDHDECQDMACENGECVNTEGSFHCFCSPPLTLDLSQQRCVNSTSGLEDLPDHDIHTDICWKKVTNYVCSHPLHGRRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPEDLHYGLYGPEGAPFYNYLGPEDAIPEPLFPNTVSRPEDHTLVLEPPLQPSELQPHYVASHPENQAGFEGLQAEECGILNGCDNGRCVRVREGYTCDCFEGFQLDTAQMACVDVNECDDLNGPAALCVHGHCENTEGSYRCHCPPGYVAEAGPPHCTAKE", "length": 1760, "header": "tr|A0A5G2QLH2-1|A0A5G2QLH2_PIG Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 2 OS=Sus scrofa OX=9823 GN=LTBP2 PE=1 SV=2 CANONICAL=A0A5G2R7P3-1" }, "locus": { "chromosome": "7", "start_pos": 97852097, "end_pos": 97748104, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066921.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066921.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062925.2", "url": "https://www.ensembl.org/id/ENSSSCP00000062925.2" } ] } }, { "isoform_ac": "A0A5G2QZZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3/entry#A0A5G2QZZ4-1", "sequence": { "sequence": "MRPSTTRRCPGRALRNPWRSFLPLTLALFVGLGHAQRDPVGRYEPAGRDANRLRRPGGSHPAAAAAKVYGLFRDQDASVPGLPPEERAQPGWGSARRPAETEARRPPRAQQPRRVQPPAQTWRSRSLSQQQPASRDRAAAALPRLGTVQRPRAARGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCQPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPEEEFDPQNSRPAPRRSAEGSPNLRRSSAARESSTARMRPPAPQPPPARTLSRLSQTHPSQQHMGLSQTVRLYPAAAASGQLTSNALPVGPGPERRDGAQQTAYVDHLSSPWGLNLTEKIKKIKIVFTPTICKQTCAHGRCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPAPRLDPEPPERGPRHRTPLEGSLKQSTFTLPLSNQLASVNPSLVKVHIHHPPEASVQVHQVARVRGEAEGAPEENSVETRPSPRFPTGPGHSPWSSNSIPTRSREAPRPPPPAVPRLRPLLGRCYLSAVNGQCANPLLELTAQEDCCGSVGAFWGVTSCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDVNECLTLGLCEDSECVNTRGSYLCTCRPGLLLDPSRSRCVSDKAVSMQQGLCYRLLGPGTCALPLAQRITKQICCCSRVGKAWGSKCETCPLPGTEAFREICPAGHGYTYSSSDIRLSMRKAEEEELARPSWEHVQKSHGTPPGPADRQPLRAATGTWLEAGTIPDKGDTQAGQVTTSVTQLATWVPGDAIGRPTPSLPARGIPEAQEEEQVTAPTDVLVTPAPPAIDRCATGATNICGPGTCVNLPDGYKCICSPGYRLHPSQAYCTDDNECLRDPCKGRGRCVNRVGSYSCFCYPGYMLATSGATQECQDINECRHPGTCPDGRCVNSPGSYTCLPCEEGYRGQSGSCVDVNECLTPGVCAHGTCLNLEGSFRCSCEPGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFTCSACESGYWVNEDGTACEDLDECAFPGVCPSGVCANTAGSFSCRDCEEGYRPSALGHTCEDVDECADPQSRCLGGECKNTAGSYQCLCPQGFQLTNGSVCEDVDECVGEEYCAPRGECLNSHGSFFCLCAPGFASADGGTSCQDVDECAVTDRCLRGQCVNTEGSFNCLCETGFQPSPESEECVDIDECANDTVCGSHGYCDNTEGSFRCLCDQGFETSASGWDCVDVNECELMLAVCGTALCENVEGSFLCLCANDLEEYDAQEGHCRPRLAGGQSIPEASPGDRSPVPIRMECYSGQKGQPPCSSLLGRNTTQAECCCTQGTGWGDACDLCPAEDSVEFSEICPSGKGYVPVEGAWMFGQTTYTDADECVMFGHALCRNGRCLNTVPGYICLCNPGYHYDASRHKCEDHDECQDMACENGECVNTEGSFHCFCSPPLTLDLSQQRCVNSTSGLEDLPDHDIHTDICWKKVTNYVCSHPLHGRRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPEDLHYGLYGPEGAPFYNYLGPEDAIPEPLFPNTVSRPEDHTLVLEPPLQPSELQPHYVASHPENQAGFEGLQAEECGILNGCDNGRCVRVREGYTCDCFEGFQLDTAQMACVDVNECDDLNGPAALCVHGHCENTEGSYRCHCPPGYVAEAGPPHCTAKE", "length": 1730, "header": "tr|A0A5G2QZZ4-1|A0A5G2R7P3_PIG Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 2 OS=Sus scrofa OX=9823 GN=LTBP2 PE=1 SV=1 CANONICAL=A0A5G2R7P3-1" }, "locus": { "chromosome": "7", "start_pos": 97852097, "end_pos": 97748104, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076384.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076384.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063825.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063825.1" } ] } }, { "isoform_ac": "A0A5G2R7P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3/entry#A0A5G2R7P3-1", "sequence": { "sequence": "MRPSTTRRCPGRALRNPWRSFLPLTLALFVGLGHAQRDPVGRYEPAGRDANRLRRPGGSHPAAAAAKVYGLFRDQDASVPGLPPEERAQPGWGSARRPAETEARRPPRAQQPRRVQPPAQTWRSRSLSQQQPASRDRAAAALPRLGTVQRPRAARGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCQPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPEEEFDPQNSRPAPRRSAEGSPNLRRSSAARESSTARMRPPAPQPPPARTLSRLSQTHPSQQHMGLSQTVRLYPAAAASGQLTSNALPVGPGPERRDGAQQTAYVDHLSSPWGLNLTEKIKKIKIVFTPTICKQTCAHGRCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPAPRLDPEPPERGPRHRTPLEGSLKQSTFTLPLSNQLASVNPSLVKVHIHHPPEASVQVHQVARVRGEAEGAPEENSVETRPSPRFPTGPGHSPWSSNSIPTRSREAPRPPPPAVPRLRPLLGRCYLSAVNGQCANPLLELTAQEDCCGSVGAFWGVTSCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDVNECLTLGLCEDSECVNTRGSYLCTCRPGLLLDPSRSRCVSDKAVSMQQGLCYRLLGPGTCALPLAQRITKQICCCSRVGKAWGSKCETCPLPGTEAFREICPAGHGYTYSSSDIRLSMRKAEEEELARPSWEHVQKSHGTPPGPADRQPLRAATGTWLEAGTIPDKGDTQAGQVTTSVTQLATWVPGDAIGRPTPSLPARGIPEAQEEEQVTAPTDVLVTPAPPAIDRCATGATNICGPGTCVNLPDGYKCICSPGYRLHPSQAYCTDDNECLRDPCKGRGRCVNRVGSYSCFCYPGYMLATSGATQECQDIDECEQPGLCSGGRCTNTVGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLPCEEGYRGQSGSCVDVNECLTPGVCAHGTCLNLEGSFRCSCEPGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFTCSACESGYWVNEDGTACEDLDECAFPGVCPSGVCANTAGSFSCRDCEEGYRPSALGHTCEDVDECADPQSRCLGGECKNTAGSYQCLCPQGFQLTNGSVCEDVDECVGEEYCAPRGECLNSHGSFFCLCAPGFASADGGTSCQDVDECAVTDRCLRGQCVNTEGSFNCLCETGFQPSPESEECVDIDKCEDSGDSACGAWRCENSPGSHRCILGCQPGFHVAPAGDGIDIDECANDTVCGSHGYCDNTEGSFRCLCDQGFETSASGWDCVDVNECELMLAVCGTALCENVEGSFLCLCANDLEEYDAQEGHCRPRLAGGQSIPEASPGDRSPVPIRMECYSGQKGQPPCSSLLGRNTTQAECCCTQGTGWGDACDLCPAEDSVEFSEICPSGKGYVPVEGAWMFGQTTYTDADECVMFGHALCRNGRCLNTVPGYICLCNPGYHYDASRHKCEDHDECQDMACENGECVNTEGSFHCFCSPPLTLDLSQQRCVNSTSGLEDLPDHDIHTDICWKKVTNYVCSHPLHGRRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPEDLHYGLYGPEGAPFYNYLGPEDAIPEPLFPNTVSRPEDHTLVLEPPLQPSELQPHYVASHPENQAGFEGLQAEECGILNGCDNGRCVRVREGYTCDCFEGFQLDTAQMACVDVNECDDLNGPAALCVHGHCENTEGSYRCHCPPGYVAEAGPPHCTAKE", "length": 1814, "header": "tr|A0A5G2R7P3-1|A0A5G2R7P3_PIG Isoform 1 of Latent-transforming growth factor beta-binding protein 2 OS=Sus scrofa OX=9823 GN=LTBP2 PE=1 SV=1 CANONICAL=A0A5G2R7P3-1" }, "locus": { "chromosome": "7", "start_pos": 97852097, "end_pos": 97748104, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082622.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082622.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073277.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073277.1" } ] } }, { "isoform_ac": "A0A8W4FDF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3/entry#A0A8W4FDF9-1", "sequence": { "sequence": "MRPSTTRRCPGRALRNPWRSFLPLTLALFVGLGHAQRDPVGRYEPAGRDANRLRRPGGSHPAAAAAKVYGLFRDQDASVPGLPPEERAQPGWGSARRPAETEARRPPRAQQPRRVQPPAQTWRSRSLSQQQPASRDRAAAALPRLGTVQRPRAARGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCQPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPEEEFDPQNSRPAPRRSAEGSPNLRRSSAARESSTARMRPPAPQPPPARTLSRLSQTHPSQQHMGLSQTVRLYPAAAASGQLTSNALPVGPGPERRDGAQQTAYVDHLSSPWGLNLTEKIKKIKIVFTPTICKQTCAHGRCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPAPRLDPEPPERGPRHRTPLEGSLKQSTFTLPLSNQLAFWGVTSCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDVNECLTLGLCEDSECVNTRGSYLCTCRPGLLLDPSRSRCVSDKAVSMQQGLCYRLLGPGTCALPLAQRITKQICCCSRVGKAWGSKCETCPLPGTEAFREICPAGHGYTYSSSDIRLSMRKAEEEELARPSWEHVQKSHGTPPGPADRQPLRAATGTWLEAGTIPDKGIWAGEDVTTSVTQLATWVPGDAIGRPTPSLPARGIPEAQEEEQVTAPTDVLVTPAPPAIDRCATGATNICGPGTCVNLPDGYKCICSPGYRLHPSQAYCTDDNECLRDPCKGRGRCVNRVGSYSCFCYPGYMLATSGATQECQDIDECEQPGLCSGGRCTNTVGSYHCECDQGYIMQSSLQLLPFGPTSLTQWPVSDVDECASRASCPTGLCLNTEGSFTCSACESGYWVNEDGGPENAGLPTSQRHSICWASGPYEYLDECAFPGVCPSGVCANTAGSFSCRDCEEGYRPSALGHTCEDVDECADPQSRCLGGECKNTAGSYQCLCPQGFQLTNGSVCEDVDECVGEEYCAPRGECLNSHGSFFCLCAPGFASADGGTSCQDVDECAVTDRCLRGQCVNTEGSFNCLCETGFQPSPESEECVDIDECANDTVCGSHGYCDNTEGSFRCLCDQGFETSASGWDCVDVNECELMLAVCGTALCENVEGSFLCLCANDLEEYDAQEGHCRPRLAGGQSIPEASPGDRSPVPIRMECYSGQKGQPPCSSLLGRNTTQAECCCTQGTGWGDACDLCPAEDSVEFSEICPSGKGYVPVEGAWMFGQTTYTDADECVMFGHALCRNGRCLNTVPGYICLCNPGYHYDASRHKCEDHDECQDMACENGECVNTEGSFHCFCSPPLTLDLSQQRCVNSTSGLEDLPDHDIHTDICWKKVTNYVCSHPLHGRRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPEDLHYGLYGPEGAPFYNYLGPEDAIPEPLFPNTVSRPEDHTLVLEPPLQPSELQPHYVASHPENQAGFEGLQAEECGILNGCDNGRCVRVREGYTCDCFEGFQLDTAQMACVDVNECDDLNGPAALCVHGHCENTEGSYRCHCPPGYVAEAGPPHCTAKE", "length": 1606, "header": "tr|A0A8W4FDF9-1|A0A5G2R7P3_PIG Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 2 OS=Sus scrofa OX=9823 GN=LTBP2 PE=1 SV=1 CANONICAL=A0A5G2R7P3-1" }, "locus": { "chromosome": "7", "start_pos": 97852097, "end_pos": 97748104, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094151.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094151.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076340.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076340.1" } ] } }, { "isoform_ac": "F1S2T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3/entry#F1S2T5-1", "sequence": { "sequence": "MRPSTTRRCPGRALRNPWRSFLPLTLALFVGLGHAQRDPVGRYEPAGRDANRLRRPGGSHPAAAAAKVYGLFRDQDASVPGLPPEERAQPGWGSARRPAETEARRPPRAQQPRRVQPPAQTWRSRSLSQQQPASRDRAAAALPRLGTVQRPRAARGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCQPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPEEEFDPQNSRPAPRRSAEGSPNLRRSSAARESSTARMRPPAPQPPPARTLSRLSQTHPSQQHMGLSQTVRLYPAAAASGQLTSNALPVGPGPERRDGAQQTAYVDHLSSPWGLNLTEKIKKIKIVFTPTICKQTCAHGRCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPAPRLDPEPPERGPRHRTPLEGSLKQSTFTLPLSNQLASVNPSLVKVHIHHPPEASVQVHQVARVRGEAEGAPEENSVETRPSPRFPTGPGHSPWSSNSIPTRSREAPRPPPPAVPRLRPLLGRCYLSAVNGQCANPLLELTAQEDCCGSVGAFWGVTSCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDVNECLTLGLCEDSECVNTRGSYLCTCRPGLLLDPSRSRCVSDKAVSMQQGLCYRLLGPGTCALPLAQRITKQICCCSRVGKAWGSKCETCPLPGTEAFREICPAGHGYTYSSSDIRLSMRKAEEEELARPSWEHVQKSHGTPPGPADRQPLRAATGTWLEAGTIPDKGDTQAGQVTTSVTQLATWVPGDAIGRPTPSLPARGIPEAQEEEQVTAPTDVLVTPAPPAIDRCATGATNICGPGTCVNLPDGYKCICSPGYRLHPSQAYCTDDNECLRDPCKGRGRCVNRVGSYSCFCYPGYMLATSGATQECQDIDECEQPGLCSGGRCTNTVGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLPCEEGYRGQSGSCVDVNECLTPGVCAHGTCLNLEGSFRCSCEPGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFTCSACESGYWVNEDGTACEDLDECAFPGVCPSGVCANTAGSFSCRDCEEGYRPSALGHTCEDVDECADPQSRCLGGECKNTAGSYQCLCPQGFQLTNGSVCEDVDECVGEEYCAPRGECLNSHGSFFCLCAPGFASADGGTSCQDVDECAVTDRCLRGQCVNTEGSFNCLCETGFQPSPESEECVDIDECANDTVCGSHGYCDNTEGSFRCLCDQGFETSASGWDCVDVNECELMLAVCGTALCENVEGSFLCLCANDLEEYDAQEGHCRPRLAGGQSIPEASPGDRSPVPIRMECYSGQKGQPPCSSLLGRNTTQAECCCTQGTGWGDACDLCPAEDSVEFSEICPSGKGYVPVEGAWMFGQTTYTDADECVMFGHALCRNGRCLNTVPGYICLCNPGYHYDASRHKCEDHDECQDMACENGECVNTEGSFHCFCSPPLTLDLSQQRCVNSTSGLEDLPDHDIHTDICWKKVTNYVCSHPLHGRRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPEDLHYGLYGPEGAPFYNYLGPEDAIPEPLFPNTVSRPEDHTLVLEPPLQPSELQPHYVASHPENQAGFEGLQAEECGILNGCDNGRCVRVREGYTCDCFEGFQLDTAQMACVDVNECDDLNGPAALCVHGHCENTEGSYRCHCPPGYVAEAGPPHCTAKE", "length": 1770, "header": "tr|F1S2T5-1|A0A5G2R7P3_PIG Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 2 OS=Sus scrofa OX=9823 GN=LTBP2 PE=1 SV=3 CANONICAL=A0A5G2R7P3-1" }, "locus": { "chromosome": "7", "start_pos": 97852097, "end_pos": 97748104, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002632.4", "url": "https://www.ensembl.org/id/ENSSSCT00000002632.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002566.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002566.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FDF9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDF9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514300", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514300", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M3H2-1", "protein_name": "Latent-transforming growth factor beta-binding protein 2", "gene_name": "LTBP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVWIKETKNQGEVSKNKTLQFSFRRLQRPGEGAKVQQRCAPSGRRSAASRLGARSPRPLPPPGSGSRESLARSLTRGPLDGKRRATGRGPERSQRATGAPTVSPRGRSPRARAQLSRRPGSMRPPTTARCPGRVLQNPWRSFWPLTLALFVGMGQAQRDPVGRYEPAGRDASRLRRPGGSPVVATAKVYSLFREQDAPVRGSPPAELVQPSWGSPRRSTEAEARRPPRAQQPRRVQPPAQTWRSRPSGQQQSAPRARAAPALPRLETVQRPRAARGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCQPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPEEEFDPQNSRPAPRRSAEGPPSLRRSSVARESTTARVRPPAPQLQRARTLSGLSQTRSSQQHVGLSQTTRLYPAPAASGQLTSNALPMGPGPERRDGAPQAAYLDRPSSSWGLNLTEKIKKIKIVFTPTICKQTCARGRCANSCERGDTTTLYSQSGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPAPRLDQEPPERGPRHRAPLEGPLKQSTFTLPLSNQLASVNPSLVNVHIRHPPEASVQIHQVARVRGEAEEAPEENSVETRPSPRLPAGPGPGRWDSNRIPARSGEAPRLPPPVVPRTPALLGRCYLSTLNGQCANPLPELTAHEDCCGSVGAFWGVTSCAPCPPRPASPVIENGQLECPQGYKRLNLTHCEDVNECLTLGLCEDSECVNTRGSYLCTCRPGLLLDPSRSRCVSDKAVSMQQGLCYRLLGPGTCALPLAQRITKQICCCSRVGKAWGSLCEKCPLPGTEAFREICPAGHGYTYSSSDIRLSMRKAEEEELARPSRDRGPKRNGTLPRPAERQPLRAATGTWVEAETIPDKGIWFGEEVTTSVTQLSTWVPGGALGTPTPSVPEQGIPEAREEAQVTAPTNVLVTPAPSGIDRCAAGATNICGPGTCVNLPDGYRCICSPGYRLHPSQAYCTDDNECLRDPCKGRGRCVNRVGSYSCFCYPGYKLATSGATQECQDIDECEQPGVCSRGRCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGKCVNSPGSYTCLPCEEGYRGQGGSCVDVNECLTPGVCTHGTCINLEGSFRCSCEQGYEVTPDEKGCQDVDECAIRASCPTGLCLNTEGSFTCSACESGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCRDCEAGYQPSALGHTCEDVDECEDPQSSCLGGECKNTAGSYQCLCPPGFQLANGTVCEDVDECVGEEYCAPRGECLNSHGSFFCLCADGFVSADGGTSCQDVDECAVTDRCLGGQCVNTDGSFNCVCETGFQPSPESGECVDIDECEDLGEPICGAWRCENSPGSYRCVLGCQPGFHMAPTGDCIDIDECANDTVCGSHGFCDNTDGSFRCLCDQGFETSPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGRCRPRGAGGPSVPEARPGAHPPGPVRMECYSGQKDQTPCSSLLGRNTTQAECCCTQGTGWGDACDLCPDEDSVEFSEICPSGKGYIPVEGAWMFGQTTYTDADECVMFGPGLCRNGRCLNTVPGYICLCNPGYHYNAASRKCEDHDECQDMACENGECVNTEGSFHCFCSPPLTLDLSQQRCVNSTSGVEDLPDHDIHMDICWKRVTNYVCSHPLHGRRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGIHFRPGYEYSPGPDDLHYSLYGPDGVPFYNYLGPEDAIPEPLFPSTAGRPGDRIPLPEPPLQPSELQPHYVASHPGLCCCKNGEEVGSEAVSLPSSPSAHHCQQEHQAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDTAHMACVDVNECDDLNGPAALCVHGHCENTEGSYRCHCLPGYVAEAGPPHCTAKE", "length": 1963 }, "evidence": [ { "id": "A0A5G2R7P3", "url": "https://omabrowser.org/oma/group/A0A5G2R7P3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0XNW8-1", "protein_name": "Latent-transforming growth factor beta-binding protein 1", "gene_name": "LTBP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPAPRRRPSPAPRADSMRGAAASVLPLTFAILLGLGDCQRDLAARLEPGASRRADPRRLRGQTAPLGATGTAPGLPRPHRAPPEPAALPAALRPERGPAESPNDGRRQRPEPGLGPAQGLQPSRQRPRSALKARVAPRAKEPNGRGRMAGPNVCGRQCCSGWAVAPGTNHCIKPVCDPPCQNKGSCSRPHVCTCRSGFQGSRCEEVVPEQEYHPPSIALQPPAGSLRRRTGTAERDASPREAQAPVPRHAPTRTQSRIGSPVSTQHTGPSRTVRRYPASNGQLTSNTLPNGHGHEQGSSGPNAAFQEHTLAARGANLTEKIRKIKIIFTPTICKQTCRNGRCYNSCEKGDTTTLYSQGGHDHDPKSGFRIYFCQIPCLNGGRCVGRDECWCPSNSTGKFCHLPAPSPEKKQGGKAPNTVASGSMKHSTYILPLSNQLASLNPSLVNVHINHPPEATVQIHQVARVRGDSEVSEENSVEAVLVPQMAAVPWYTYSNGNGNSIATEGGQQQRPPGLLGRCFREALHGQCTNPLPGLTLLEDCCGSVGLFWGVDRCLACPPRPAHPVIENGQVECPQGYKRLNRSHCQDINECLMQGLCKDAKCLNTRGSFRCTCRPGTMLDPSRSHCISDKAVSMEQGLCYRSAAGGVCSFPLSHRITQQICCCSRVGKGWGKNCEECPVPGSGAFKEICPAGHGYTYSSSDIRLSMRKAEAEELPLSLEEHSESSNWTLDWAARRQRLQDSLHGSVLEALPHPDISAGEGEVFPAGQDAADITPEPEAHRVEEEESRRAPPQPGPTTTWADAAPTQIPAQGSEASGCASSSLACGAGVCVLTPDGYSCSCHLGYTLHPSRLHCVDEDECLQDPCTGKGHCVNSVGSYSCLCYSGYTLVFLESKQSCQDRDECEQPSTCPGQRCVNTPGSYRCECKEGFAMGLRGQCEDINECVDPSPCPHGKCVNTPGSYRCVGCADGYQPRNGRCIDVDECLVERTCAHGQCINLDGSFRCSCYRGYEVAPDGKSCEDIDECTAQAACPSRLCLNTEGSYSCMACDAGYTVSRDGSTCEDVDECADLAIQCLGGACRNTLGSYECHCQAGFELINGTVCQDVNECLNSEICSPNGECLNSHGSYFCICAPGFSSSDGGVNCQDVDECTDKSRCSQGQCLNTEGSYRCLCENGFKHSQETDDCIDVDECKEYGDAICGTWRCQNSLGSYRCIMGCQPGFHWTPPGDCIDIDECANETLCGSHGFCENSDGSFRCLCDRGYESSPSGHYCVDVNECELMVAVCGTALCENVEGSFLCLCPSDHEEYDTEAGQCRPRAAVEGPERHTAQPSDSMERKQCYYHISDVRLCDSVLAKNVTKQECCCTVGAAWGDNCETYPCPILGTVEYQEICPLGKGYVPQEDPLSGKVSFTDMDECETFGSEFCRNGQCLNTVPGYKCFCRTGYFYDVGRLECVDQDECQNEVYCINGECLNTVGSYHCFCSLPLVLDATGNRCVNLSGRADALEEYEIHLDVCWQTVSDYICQDLLHGEQTTYTECCCRLGEAWGQNCALCPHRSSADFAFLCNGASEDSDRGAEVRERPRYEYGPGLEDPHYGLPSPDMGPYYNYLESEYGNPDVAFPRRELSSEFRGSPFHHGPGRPPPRYLPSQPGLYEGFEGLQAEECGILNGCENGRCVRVPEGYTCDCFDGYQLDMTLMACVDINECEDVDVPVPLCQGGTCENTEGSYRCRCLPGYVALAQPHHCVPQTAQSPAAA", "length": 1751 }, "evidence": [ { "id": "A0A5G2R7P3", "url": "https://omabrowser.org/oma/group/A0A5G2R7P3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O08999-1", "protein_name": "Latent-transforming growth factor beta-binding protein 2", "gene_name": "Ltbp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAPTTARCSGCIQRVRWRGFLPLVLAVLMGTSHAQRDSIGRYEPASRDANRLWHPVGSHPAAAAAKVYSLFREPDAPVPGLSPSEWNQPAQGNPGWLAEAEARRPPRTQQLRRVQPPVQTRRSHPRGQQQIAARAAPSVARLETPQRPAAARRGRLTGRNVCGGQCCPGWTTSNSTNHCIKPVCQPPCQNRGSCSRPQVCICRSGFRGARCEEVIPEEEFDPQNARPVPRRSVERAPGPHRSSEARGSLVTRIQPLVPPPSPPPSRRLSQPWPLQQHSGPSRTVRRYPATGANGQLMSNALPSGLELRDSSPQAAHVNHLSPPWGLNLTEKIKKIKVVFTPTICKQTCARGRCANSCEKGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPVPQPDREPAGRGSRHRTLLEGPLKQSTFTLPLSNQLASVNPSLVKVQIHHPPEASVQIHQVARVRGELDPVLEDNSVETRASHRPHGNLGHSPWASNSIPARAGEAPRPPPVLSRHYGLLGQCYLSTVNGQCANPLGSLTSQEDCCGSVGTFWGVTSCAPCPPRQEGPAFPVIENGQLECPQGYKRLNLSHCQDINECLTLGLCKDSECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAVSMQQGLCYRSLGSGTCTLPLVHRITKQICCCSRVGKAWGSTCEQCPLPGTEAFREICPAGHGYTYSSSDIRLSMRKAEEEELASPLREQTEQSTAPPPGQAERQPLRAATATWIEAETLPDKGDSRAVQITTSAPHLPARVPGDATGRPAPSLPGQGIPESPAEEQVIPSSDVLVTHSPPDFDPCFAGASNICGPGTCVSLPNGYRCVCSPGYQLHPSQDYCTDDNECMRNPCEGRGRCVNSVGSYSCLCYPGYTLVTLGDTQECQDIDECEQPGVCSGGRCSNTEGSYHCECDRGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYVGQSGSCVDVNECLTPGICTHGRCINMEGSFRCSCEPGYEVTPDKKGCRDVDECASRASCPTGLCLNTEGSFTCSACQSGYWVNEDGTACEDLDECAFPGVCPTGVCTNTVGSFSCKDCDQGYRPNPLGNRCEDVDECEGPQSSCRGGECKNTEGSYQCLCHQGFQLVNGTMCEDVNECVGEEHCAPHGECLNSLGSFFCLCAPGFASAEGGTRCQDVDECAATDPCPGGHCVNTEGSFSCLCETASFQPSPDSGECLDIDECEDREDPVCGAWRCENSPGSYRCILDCQPGFYVAPNGDCIDIDECANDTVCGNHGFCDNTDGSFRCLCDQGFETSPSGWECVDVNECELMMAVCGDALCENVEGSFLCLCASDLEEYDAEEGHCRPRVAGAQRIPEVRTEDQAPSLIRMECYSEHNGGPPCSQILGQNSTQAECCCTQGARWGKACAPCPSEDSVEFSQLCPSGQGYIPVEGAWTFGQTMYTDADECVLFGPALCQNGRCSNIVPGYICLCNPGYHYDASSRKCQDHNECQDLACENGECVNQEGSFHCLCNPPLTLDLSGQRCVNTTSSTEDFPDHDIHMDICWKKVTNDVCSQPLRGHHTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAERGAGIHFRPGYEYGPGLDDLPENLYGPDGAPFYNYLGPEDTAPEPPFSNPASQPGDNTPVLEPPLQPSELQPHYLASHSEPPASFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAPTLACVDVNECEDLNGPARLCAHGHCENTEGSYRCHCSPGYVAEPGPPHCAAKE", "length": 1813 }, "evidence": [ { "id": "A0A5G2R7P3", "url": "https://omabrowser.org/oma/group/A0A5G2R7P3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O35806-1", "protein_name": "Latent-transforming growth factor beta-binding protein 2", "gene_name": "Ltbp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAPTTVRCSGRIQRARWRGFLPLVLALLMGTSHAQRDSVGRYEPASRDANRLWRPVGNHPAAAAAKVYSLFREPDAPVPGLSPSEWNQPGQGIPGRLAEAEARRPSRAQQLRRVQSPVQTRRSNPRGQQPPAARTAHSVVRLATPQRPAAARRGRLTGRNVCGGQCCPGWTTSNSTNHCIKPVCQPPCQNRGSCSRPQLCICRSGFRGARCEEVIPEEEFDPQNARPVPRRSVEGAPGPHRSSEARGSLVTRIQPLLPPLPPPPSRTLSQTRPLQQHAGLSRTVRRYPATGTNGQLMSNALPSGPGPELRDSSQQAAHMNHLSHPWGLNLTEKIKKIKVVFTPTICKQTCARGRCANTCEKGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPVPQPDREPPGRGSQHRALLEGPLKQSTFTLPLSNQLASVNPSLVKVQMQHPPEASVQIHQVARVRGEVDPVPEDNSVETRASHRPHGSSGHSHWASNSIPARAGEAPRPPPVPSRHYGLLGQCYLSTVNGQCANPLGELTSQEDCCGSVGTSWGVTSCAPCPPRPAFPVIENGQLECPQGYKRLNLSHCQDINECLTLGLCKDSECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAVSMKQGLCYRSMVSGTCTLPLVQRITKQICCCSRVGKAWGSKCEHCPLPGTEAFREICPAGHGYAYSSSDIRLSMRKAEEEELASPVREQRQQSSGPPPGAAERQPLRAATATWIEAETLPDKGDSRAIQITTSAPHLPARVPGDATGRPTPSLPGQGIPEGPAEEQVIPSSDVLVTHGPPGFDPCFAGASNICGPGTCVKLPNGYRCVCSPGYQLHPSQDYCTDDNECLRNPCEGRGRCVNSVGSYSCLCYPGYTLATLGDTQECQDVDECEQPGVCSGGRCSNTEGSYHCECDQGYVMVRRGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYIGQSGNCVDMNECLTPGICAHGRCINMEGSFRCSCEPGYELTPDKKGCRDVDECASRASCPTGLCLNTEGSFTCSACQSGYWVNEDGTACEDLDECAFPGVCPTGVCTNTVGSFSCKDCDRGFRPSPLGNSCEDVDECEGPQNSCLGGECKNTDGSYQCLCPQGFQLANGTVCEDVDECVGEEHCAPHGECLNSPGSFFCLCAPGFASAEGGTRCQDVDECATTEPCLGGHCVNTEGSFNCLCETGFQPAPDSGECVDIDECANDTVCGNHGFCDNTDGSFRCLCDQGFETSPSGWECVDVNECELMLAVCGDALCENVEGSFLCLCASDLEEYDAEEGHCRPRVAGAQRIPEVPTEEQAAGLTGMECYAEHNGGPPCSQILGQNSTQAECCSTQGARWGETCDPCPSEDSVEFSELCPSGQGYIPVEGAWTFGQAMYTDADECILFGPALCQNGRCLNTVPGYICLCNPGYHYDAVSRKCQDHNECQDLACENGECVNTEGSFHCFCSPPLILDLSGQRCVNSTSSSEDFPDHDIHMDICWKKVTNDVCSQPLRGHHTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGIHFRPGYEYGPGPDDLPETLYGPDGAPFYNYLGPEDTVPEPPFSNTASHLGDNTPILEPPLQPSELQPPAIQNPLASFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDTALMACVDVNECEDLNGAARLCAHGHCENTEGSYRCHCSPGYVAEPGPPHCAAKE", "length": 1764 }, "evidence": [ { "id": "A0A5G2R7P3", "url": "https://omabrowser.org/oma/group/A0A5G2R7P3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14767-1", "protein_name": "Latent-transforming growth factor beta-binding protein 2", "gene_name": "LTBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPRTKARSPGRALRNPWRGFLPLTLALFVGAGHAQRDPVGRYEPAGGDANRLRRPGGSYPAAAAAKVYSLFREQDAPVAGLQPVERAQPGWGSPRRPTEAEARRPSRAQQSRRVQPPAQTRRSTPLGQQQPAPRTRAAPALPRLGTPQRSGAAPPTPPRGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCEPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPDEEFDPQNSRLAPRRWAERSPNLRRSSAAGEGTLARAQPPAPQSPPAPQSPPAGTLSGLSQTHPSQQHVGLSRTVRLHPTATASSQLSSNALPPGPGLEQRDGTQQAVPLEHPSSPWGLNLTEKIKKIKIVFTPTICKQTCARGHCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPIPQPDREPPGRGSRPRALLEAPLKQSTFTLPLSNQLASVNPSLVKVHIHHPPEASVQIHQVAQVRGGVEEALVENSVETRPPPWLPASPGHSLWDSNNIPARSGEPPRPLPPAAPRPRGLLGRCYLNTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHGYTYASSDIRLSMRKAEEEELARPPREQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDLACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYVASHPEPPAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHCTAKE", "length": 1821 }, "evidence": [ { "id": "A0A5G2R7P3", "url": "https://omabrowser.org/oma/group/A0A5G2R7P3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3" } ], "pmid": "" }, { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3" } ], "pmid": "" }, { "name": "microfibril binding", "id": "GO:0050436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050436", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "supramolecular fiber organization", "id": "GO:0097435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097435", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1163, "end_pos": 1165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1302, "end_pos": 1304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1423, "end_pos": 1425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1561, "end_pos": 1563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 605, "end_pos": 607, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 182, "end_pos": 214, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R7P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7P3" }, { "id": "PS51364", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51364" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TB", "eco_id": "ECO_0000259", "start_pos": 541, "end_pos": 584, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1163, "end_pos": 1165 }, { "start_pos": 1302, "end_pos": 1304 }, { "start_pos": 1423, "end_pos": 1425 }, { "start_pos": 1561, "end_pos": 1563 }, { "start_pos": 176, "end_pos": 178 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 605, "end_pos": 607 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7M3-1", "uniprot_ac": "A0A5G2R7M3", "uniprot_id": "A0A5G2R7M3_PIG", "mass": { "chemical_mass": 108898.0, "monoisotopic_mass": 108898.0 }, "refseq": {}, "gene_names": [ { "name": "ITIH4", "type": "recommended", "evidence": [ { "id": "A0A5G2R7M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3" } ] } ], "protein_names": [ { "name": "Inter-alpha-trypsin inhibitor heavy chain 4", "type": "synonym", "evidence": [ { "id": "A0A5G2R7M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7M3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ITIH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3", "locus": { "chromosome": "13", "start_pos": 34928439, "end_pos": 34948229, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011453", "url": "https://www.ensembl.org/id/ENSSSCG00000011453" } ] } } ], "crossref": [ { "id": "A0A5G2R7M3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7M3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011453", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011453", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01461", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01461", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10338", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10338", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10338:SF119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10338:SF119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06668", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06668", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZN24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZN24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZN24-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZN24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZT99", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZT99-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BGD6", "url": "https://www.uniprot.org/uniprotkb/A0A287BGD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BGD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BGD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QEW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QEW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QN24", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QN24-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QU18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QU18-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7M3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCE0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SH92", "url": "https://www.uniprot.org/uniprotkb/F1SH92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SH92-1", "url": "https://www.uniprot.org/uniprotkb/F1SH92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTRFSPALQDSFHFMPQCLCVWSCQIQGTAEACPAGTARPWTVQGWSGSDWLGADACSDVLPVPWAEASLTGRGAKMKTLSPTGAYGLLLVLPLLLAVLQSTTAHKNDINIYSLTVDSKVSSRFAHTVVTSRVVNKGSAVQEATFQMELPKKAFITNFSMIIDGVTYPGNIKEKAAAQEQYSAAVARGESAGLVRATGRKTEQFQVAVSVAPAAKVTFELVYEELLARHLGVYELLLKIQPQQLVKHLQMDIHIFEPQGISFLETESTFMTNELAEALTISQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNFIVRYDVNRTVTGGSIQIENGYFVHYFAPEGLSAIPKNVVFVIDTSGSMRGRKIQQTREALIKILGDLGSRDQFNLVSFSGEATQWKKGLLPASAENVEEAKSYAAEIHAQGGTNINDAMLMAVQLLERANREELLPARSVTLIILLTDGDPTVGETNPSKIQKNVREAIDGQHSLFCLGFGFDVSYAFLEKMALENGGLARRIYEDSDSALQLEDFYQEVANPLLRLVAFEYPSNAVEAVTQDNFRLFFKGSELVVAGKLRDQSPDVLSAKVRGQLHMENVTFVMESRVAEQEAEFLSPKYIFHSFMERLWAYLTIQQLLAQTVSASDAEKKALEARALSLSLNYSFVTPLTSMVITKPEGQEQSQVAEKPVENGNRQGNTHSGHSSFQFHSVGDRTSRLTGGSSVDPVFSHRRGWKGQGPPGPLQPTRFSHPFSRITLDRVLPEVLSVPDETSHDMDSRIIGATIPPPPARIQAPSVILPLPGQSVDQLCVDLKHSQGPVKLLSDPGQGVEVTGHYEREKARFSWIEVTFKHPPLQVRASLEHIVVIRNRQSSAYKWKETLYSVMPGLKITMDKAGLLLLSSPNRVTIGLLSWDGPGKGLRLLLRDTDHFSSQISGTFGQFYQDVVWGPPAAADDSKRTVTVQGHDHSATRELKLDYQEGSPGKEISCWTVVL", "length": 988, "header": "tr|A0A5G2R7M3-1|A0A5G2R7M3_PIG Isoform 1 of Inter-alpha-trypsin inhibitor heavy chain 4 OS=Sus scrofa OX=9823 GN=ITIH4 PE=1 SV=2 CANONICAL=A0A5G2R7M3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZN24-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3/entry#A0A286ZN24-1", "sequence": { "sequence": "AQTPLPTPYLWNNQTIPPSLVQNDINIYSLTVDSKVSSRFAHTVVTSRVVNKGSAVQEATFQMELPKKAFITNFSMIIDGVTYPGNIKEKAAAQEQYSAAVARGESAGLVRATGRKTEQFQVAVSVAPAAKVTFELVYEELLARHLGVYELLLKIQPQQLVKHLQMDIHIFEPQGISFLETESTFMTNELAEALTISQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNFIVRYDVNRTVTGGSIQIENGYFVHYFAPEGLSAIPKNVVFVIDTSGSMRGRKIQQTREALIKILGDLGSRDQFNLVSFSGEATQWKKGLLPASAENVEEAKSYAAEIHAQGGTNINDAMLMAVQLLERANREELLPARSVTLIILLTDGDPTVGETNPSKIQKNVREAIDGQHSLFCLGFGFDVSYAFLEKMALENGGLARRIYEDSDSALQLEDFYQEVANPLLRLVAFEYPSNAVEAVTQDNFRLFFKGSELVVAGKLRDQSPDVLSAKVRGQLHMENVTFVMESRVAEQEAEFLSPKYIFHSFMERLWAYLTIQQLLAQTVSASDAEKKALEARALSLSLNYSFVTPLTSMVITKPEGQEQSQVAEKPVENGNRQGNTHSGHSSFQFHSVGDRTSRLTGGSSVDPVFSHRRGWKGQAQGFEKMSYLPPRLGPPGPLQPTRFSHPFSRITLDRVLPEVLSVPDETSHDMDSRIIGTARPETIPVVPARIQAPSVILPLPGQSVDQLCVDLKHSQGPVKLLSDPGQGVEVTGHYEREKARFSWIEVTFKHPPLQVRASLEHIVVIRNRQSSAYKWKETLYSVMPGLKITMDKAGLLLLSSPNRVTIGLLSWDGPGKGLRLLLRDTDHFSSQISGTFGQFYQDVVWGPPAAADDSKRTVTVQGHDHSATRELKLDYQEGSPGKEISCWTVVL", "length": 921, "header": "tr|A0A286ZN24-1|A0A5G2R7M3_PIG Computationally mapped isoform of Inter-alpha-trypsin inhibitor heavy chain 4 OS=Sus scrofa OX=9823 GN=ITIH4 PE=1 SV=2 CANONICAL=A0A5G2R7M3-1" }, "locus": { "chromosome": "13", "start_pos": 34942854, "end_pos": 34928613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038206.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038206.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033031.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033031.2" } ] } }, { "isoform_ac": "A0A286ZT99-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3/entry#A0A286ZT99-1", "sequence": { "sequence": "MSTRFSPALQDSFHFMPQCLCVWSCQIQGTAEACPAGTARPWTVQGWSGSDWLGADACSDVLPVPWAEASLTGRGAKMKTLSPTGAYGLLLVLPLLLAVLQSTTAHKNDINIYSLTVDSKVSSRFAHTVVTSRVVNKGSAVQEATFQMELPKKAFITNFSMIIDGVTYPGNIKEKAAAQEQYSAAVARGESAGLVRATGRKTEQFQVAVSVAPAAKVTFELVYEELLARHLGVYELLLKIQPQQLVKHLQMDIHIFEPQGISFLETESTFMTNELAEALTISQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNFIVRYDVNRTVTGGSIQIENGYFVHYFAPEGLSAIPKNVVFVIDTSGSMRGRKIQQTREALIKILGDLGSRDQFNLVSFSGEATQWKKGLLPASAENVEEAKSYAAEIHAQGGTNINDAMLMAVQLLERANREELLPARSVTLIILLTDGDPTVGETNPSKIQKNVREAIDGQHSLFCLGFGFDVSYAFLEKMALENGGLARRIYEDSDSALQLEDFYQEVANPLLRLVAFEYPSNAVEAVTQDNFRLFFKGSELVVAGKLRDQSPDVLSAKVRGQLHMENVTFVMESRVAEQEAEFLSPKYIFHSFMERLWAYLTIQQLLAQTVSASDAEKKALEARALSLSLNYSFVTPLTSMVITKPEGQEQSQVAEKPVENGNRQGNTHSGHSSFQFHSVGDRTSRLTGSKRGEGPPGPLQPTRFSHPFSRITLDRVLPEVLSVPDETSHDMDSRIIGATIPPPPARIQAPSVILPLPGQSVDQLCVDLKHSQGPVKLLSDPGQGVEVTGHYEREKARFSWIEVTFKHPPLQVRASLEHIVVIRNRQSSAYKWKETLYSVMPGLKITMDKAGLLLLSSPNRVTIGLLSWDGPGKGLRLLLRDTDHFSSQISGTFGQFYQDVVWGPPAAADDSKRTVTVQGHDHSATRELKLDYQEGSPGKEISCWTVVL", "length": 976, "header": "tr|A0A286ZT99-1|A0A5G2R7M3_PIG Computationally mapped isoform of Inter-alpha-trypsin inhibitor heavy chain 4 OS=Sus scrofa OX=9823 GN=ITIH4 PE=1 SV=2 CANONICAL=A0A5G2R7M3-1" }, "locus": { "chromosome": "13", "start_pos": 34945703, "end_pos": 34928613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065989.2", "url": "https://www.ensembl.org/id/ENSSSCT00000065989.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034791.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034791.2" } ] } }, { "isoform_ac": "A0A287BGD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3/entry#A0A287BGD6-1", "sequence": { "sequence": "MKTLSPTGAYGLLLVLPLLLAVLQSTTAHKNDINIYSLTVDSKVSSRFAHTVVTSRVVNKGSAVQEATFQMELPKKAFITNFSMIIDGVTYPGNIKEKAAAQEQYSAAVARGESAGLVRATGRKTEQFQVAVSVAPAAKVTFELVYEELLARHLGVYELLLKIQPQQLVKHLQMDIHIFEPQGISFLETESTFMTNELAEALTISQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNFIVRYDVNRTVTGGSIQIENGYFVHYFAPEGLSAIPKNVVFVIDTSGSMRGRKIQQTREALIKILGDLGSRDQFNLVSFSGEATQWKKGLLPASAENVEEAKSYAAEIHAQGGTNINDAMLMAVQLLERANREELLPARSVTLIILLTDGDPTVGETNPSKIQKNVREAIDGQHSLFCLGFGFDVSYAFLEKMALENGGLARRIYEDSDSALQLEDFYQEVANPLLRLVAFEYPSNAVEAVTQDNFRLFFKGSELVVAGKLRDQSPDVLSAKVRGQLHMENVTFVMESRVAEQEAEFLSPKYIFHSFMERLWAYLTIQQLLAQTVSASDAEKKALEARALSLSLNYSFVTPLTSMVITKPEGQEQSQVAEKPVENGNRQGNTHSGHSSFQFHSVGDRTSRLTGGSSVDPVFSHRRGWKGQGPPGPLQPTRFSHPFSRITLDRVLPEVLSGATIPPPPARIQAPSVILPLPGQSVDQLCVDLKHSQGPVKLLSDPGQGVEVTGHYEREKARFSWIEVTFKHPPLQVRASLEHIVVIRNRQSSAYKWKETLYSVMPGLKITMDKAGLLLLSSPNRVTIGLLSWDGPGKGLRLLLRDTDHFSSQISGTFGQFYQDVVWGPPAAADDSKRTVTVQGHDHSATRELKLDYQEGSPGKEISCWTVVL", "length": 897, "header": "tr|A0A287BGD6-1|A0A5G2R7M3_PIG Computationally mapped isoform of Inter-alpha-trypsin inhibitor heavy chain 4 OS=Sus scrofa OX=9823 GN=ITIH4 PE=1 SV=2 CANONICAL=A0A5G2R7M3-1" }, "locus": { "chromosome": "13", "start_pos": 34943863, "end_pos": 34928613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061383.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061383.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055409.2", "url": "https://www.ensembl.org/id/ENSSSCP00000055409.2" } ] } }, { "isoform_ac": "A0A5G2QEW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3/entry#A0A5G2QEW1-1", "sequence": { "sequence": "MKTLSPTGAYGLLLVLPLLLAVLQSTTAHKNDINIYSLTVDSKVSSRFAHTVVTSRVVNKGSAVQEATFQMELPKKAFITNFSMIIDGVTYPGNIKEKAAAQEQYSAAVARGESAGLVRATGRKTEQFQVAVSVAPAAKVTFELVYEELLARHLGVYELLLKIQPQQLVKHLQMDIHIFEPQGISFLETESTFMTNELAEALTISQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNFIVRYDVNRTVTGGSIQIENGYFVHYFAPEGLSAIPKNVVFVIDTSGSMRGRKIQQTREALIKILGDLGSRDQFNLVSFSGEATQWKKGLLPASAENVEEAKSYAAEIHAQGGTNINDAMLMAVQLLERANREELLPARSVTLIILLTDGDPTVGETNPSKIQKNVREAIDGQHSLFCLGFGFDVSYAFLEKMALENGGLARRIYEDSDSALQLEDFYQEVANPLLRLVAFEYPSNAVEAVTQDNFRLFFKGSELVVAGKLRDQSPDVLSAKVRGQLHMENVTFVMESRVAEQEAEFLSPKYIFHSFMERLWAYLTIQQLLAQTVSASDAEKKALEARALSLSLNYSFVTPLTSMVITKPEGQEQSQVAEKPVENGNRQGNTHSGHSSFQFHSVGDRTSRLTGPPGPLQPTRFSHPFSRITLDRVLPEVLSVPDETSHDMDSRIIGATIPPPPARIQAPSVILPLPGQSVDQLCVDLKHSQGPVKLLSDPGQGVEVTGHYEREKARFSWIEVTFKHPPLQVRASLEHIVVIRNRQSSAYKWKETLYSVMPGLKITMDKAGLLLLSSPNRVTIGLLSWDGPGKGLRLLLRDTDHFSSQISGTFGQFYQDVVWGPPAAADDSKRTVTVQGHDHSATRELKLDYQEGSPGKEISCWTVVL", "length": 893, "header": "tr|A0A5G2QEW1-1|A0A5G2QEW1_PIG Computationally mapped isoform of Inter-alpha-trypsin inhibitor heavy chain 4 OS=Sus scrofa OX=9823 GN=ITIH4 PE=1 SV=1 CANONICAL=A0A5G2R7M3-1" }, "locus": { "chromosome": "13", "start_pos": 34943863, "end_pos": 34928613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069224.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069224.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063241.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063241.1" } ] } }, { "isoform_ac": "A0A5G2QN24-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3/entry#A0A5G2QN24-1", "sequence": { "sequence": "MPSPRDGPYLSPILPAPAGSWGESSWNNQTIPPSLVQNDINIYSLTVDSKVSSRFAHTVVTSRVVNKGSAVQEATFQMELPKKAFITNFSMIIDGVTYPGNIKEKAAAQEQYSAAVARGESAGLVRATGRKTEQFQVAVSVAPAAKVTFELVYEELLARHLGVYELLLKIQPQQLVKHLQMDIHIFEPQGISFLETESTFMTNELAEALTISQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNFIVRYDVNRTVTGGSIQIENGYFVHYFAPEGLSAIPKNVVFVIDTSGSMRGRKIQQTREALIKILGDLGSRDQFNLVSFSGEATQWKKGLLPASAENVEEAKSYAAEIHAQGGTNINDAMLMAVQLLERANREELLPARSVTLIILLTDGDPTVGETNPSKIQKNVREAIDGQHSLFCLGFGFDVSYAFLEKMALENGGLARRIYEDSDSALQLEDFYQEVANPLLRLVAFEYPSNAVEAVTQDNFRLFFKGSELVVAGKLRDQSPDVLSAKVRGQLHMENVTFVMESRVAEQEAEFLSPKYIFHSFMERLWAYLTIQQLLAQTVSASDAEKKALEARALSLSLNYSFVTPLTSMVITKPEGQEQSQVAEKPVENGGCGHSSFQFHSVGDRTSRLTGGSSVDPVFSHRRGWKGQAQGFEKMSYLPPRLGPPGPLQPTRFSHPFSRITLDRVLPEVLSVPDETSHDMDSRIIGTARPETIPVVPARIQAPSVILPLPGQSVDQLCVDLKHSQGPVKLLSDPGQGVEVTGHYEREKARFSWIEVTFKHPPLQVRASLEHIVVIRNRQSSAYKWKETLYSVMPGLKITMDKAGLLLLSSPNRVTIGLLSWDGPGKGLRLLLRDTDHFSSQISGTFGQFYQDVVWGPPAAADDSKRTVTVQGHDHSATRELKLDYQEGSPGKEISCWTVVL", "length": 930, "header": "tr|A0A5G2QN24-1|A0A5G2R7M3_PIG Computationally mapped isoform of Inter-alpha-trypsin inhibitor heavy chain 4 OS=Sus scrofa OX=9823 GN=ITIH4 PE=1 SV=1 CANONICAL=A0A5G2R7M3-1" }, "locus": { "chromosome": "13", "start_pos": 34943072, "end_pos": 34928613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077998.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077998.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065448.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065448.1" } ] } }, { "isoform_ac": "A0A5G2QU18-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3/entry#A0A5G2QU18-1", "sequence": { "sequence": "MPSPRDGPYLSPILPAPAGSWGESSWNNQTIPPSLVQNDINIYSLTVDSKVSSRFAHTVVTSRVVNKGSAVQEATFQMELPKKAFITNFSMIIDGVTYPGNIKEKAAAQEQYSAAVARGESAGLVRATGRKTEQFQVAVSVAPAAKVTFELVYEELLARHLGVYELLLKIQPQQLVKHLQMDIHIFEPQGISFLETESTFMTNELAEALTISQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNFIVRYDVNRTVTGGSIQIENGYFVHYFAPEGLSAIPKNVVFVIDTSGSMRGRKIQQTREALIKILGDLGSRDQFNLVSFSGEATQWKKGLLPASAENVEEAKSYAAEIHAQGGTNINDAMLMAVQLLERANREELLPARSVTLIILLTDGDPTVGETNPSKIQKNVREAIDGQHSLFCLGFGFDVSYAFLEKMALENGGLARRIYEDSDSALQLEDFYQEVANPLLRLVAFEYPSNAVEAVTQDNFRLFFKGSELVVAGKLRDQSPDVLSAKVRGQLHMENVTFVMESRVAEQEAEFLSPKYIFHSFMERLWAYLTIQQLLAQTVSASDAEKKALEARALSLSLNYSFVTPLTSMVITKPEGQEQSQVAEKPVENGNRQGNTHSGHSSFQFHSVGDRTSRLTGGSSVDPVFSHRRGWKGQGPPGPLQPTRFSHPFSRITLDRVLPEVLSGKTIPVVPARIQAPSVILPLPGQSVDQLCVDLKHSQGPVKLLSDPGQGVEVTGHYEREKARFSWIEVTFKHPPLQVRASLEHIVVIRNRQSSAYKWKETLYSVMPGLKITMDKAGLLLLSSPNRVTIGLLSWDGPGKGLRLLLRDTDHFSSQISGTFGQFYQDVVWGPPAAADDSKRTVTVQGHDHSATRELKLDYQEGSPGKEISCWTVVL", "length": 904, "header": "tr|A0A5G2QU18-1|A0A5G2R7M3_PIG Computationally mapped isoform of Inter-alpha-trypsin inhibitor heavy chain 4 OS=Sus scrofa OX=9823 GN=ITIH4 PE=1 SV=2 CANONICAL=A0A5G2R7M3-1" }, "locus": { "chromosome": "13", "start_pos": 34943072, "end_pos": 34928613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088757.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088757.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065490.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065490.2" } ] } }, { "isoform_ac": "A0A5G2R7M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3/entry#A0A5G2R7M3-1", "sequence": { "sequence": "MSTRFSPALQDSFHFMPQCLCVWSCQIQGTAEACPAGTARPWTVQGWSGSDWLGADACSDVLPVPWAEASLTGRGAKMKTLSPTGAYGLLLVLPLLLAVLQSTTAHKNDINIYSLTVDSKVSSRFAHTVVTSRVVNKGSAVQEATFQMELPKKAFITNFSMIIDGVTYPGNIKEKAAAQEQYSAAVARGESAGLVRATGRKTEQFQVAVSVAPAAKVTFELVYEELLARHLGVYELLLKIQPQQLVKHLQMDIHIFEPQGISFLETESTFMTNELAEALTISQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNFIVRYDVNRTVTGGSIQIENGYFVHYFAPEGLSAIPKNVVFVIDTSGSMRGRKIQQTREALIKILGDLGSRDQFNLVSFSGEATQWKKGLLPASAENVEEAKSYAAEIHAQGGTNINDAMLMAVQLLERANREELLPARSVTLIILLTDGDPTVGETNPSKIQKNVREAIDGQHSLFCLGFGFDVSYAFLEKMALENGGLARRIYEDSDSALQLEDFYQEVANPLLRLVAFEYPSNAVEAVTQDNFRLFFKGSELVVAGKLRDQSPDVLSAKVRGQLHMENVTFVMESRVAEQEAEFLSPKYIFHSFMERLWAYLTIQQLLAQTVSASDAEKKALEARALSLSLNYSFVTPLTSMVITKPEGQEQSQVAEKPVENGNRQGNTHSGHSSFQFHSVGDRTSRLTGGSSVDPVFSHRRGWKGQGPPGPLQPTRFSHPFSRITLDRVLPEVLSVPDETSHDMDSRIIGATIPPPPARIQAPSVILPLPGQSVDQLCVDLKHSQGPVKLLSDPGQGVEVTGHYEREKARFSWIEVTFKHPPLQVRASLEHIVVIRNRQSSAYKWKETLYSVMPGLKITMDKAGLLLLSSPNRVTIGLLSWDGPGKGLRLLLRDTDHFSSQISGTFGQFYQDVVWGPPAAADDSKRTVTVQGHDHSATRELKLDYQEGSPGKEISCWTVVL", "length": 988, "header": "tr|A0A5G2R7M3-1|A0A5G2R7M3_PIG Isoform 1 of Inter-alpha-trypsin inhibitor heavy chain 4 OS=Sus scrofa OX=9823 GN=ITIH4 PE=1 SV=2 CANONICAL=A0A5G2R7M3-1" }, "locus": { "chromosome": "13", "start_pos": 34945703, "end_pos": 34928613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068769.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068769.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073252.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073252.2" } ] } }, { "isoform_ac": "A0A8W4FCE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3/entry#A0A8W4FCE0-1", "sequence": { "sequence": "MSTRFSPALQDSFHFMPQCLCVWSCQIQGTAEACPAGTARPWTVQGWSGSDWLGADACSDVLPVPWAEASLTGRGAKMKTLSPTGAYGLLLVLPLLLAVLQSTTAHKNDINIYSLTVDSKVSSRFAHTVVTSRVVNKGSAVQEATFQMELPKKAFITNFSMIIDGVTYPGNIKEKAAAQEQYSAAVARGESAGLVRATGRKTEQFQVAVSVAPAAKVTFELVYEELLARHLGVYELLLKIQPQQLVKHLQMDIHIFEPQGISFLETESTFMTNELAEALTISQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNFIVRYDVNRTVTGGSIQIENGYFVHYFAPEGLSAIPKNVVFVIDTSGSMRGRKIQQTREALIKILGDLGSRDQFNLVSFSGEATQWKKGLLPASAENVEEAKSYAAEIHAQGGTNINDAMLMAVQLLERANREELLPARSVTLIILLTDGDPTVGETNPSKIQKNVREAIDGQHSLFCLGFGFDVSYAFLEKMALENGGLARRIYEDSDSALQLEDFYQEVANPLLRLVAFEYPSNAVEAVTQDNFRLFFKGSELVVAGKLRDQSPDVLSAKVRGQLHMENVTFVMESRVAEQEAEFLSPKYIFHSFMERLWAYLTIQQLLAQTVSASDAEKKALEARALSLSLNYSFVTPLTSMVITKPEGQEQSQVAEKPVENGNRQGNTHSGHSSFQFHSVGDRTSRLTGSKRGEGPPGPLQPTRFSHPFSRITLDRVLPEVLSVPDETSHDMDSRIIGTARPETIPVVPARIQAPSVILPLPGQSVDQLCVDLKHSQGPVKLLSDPGQGVEVTGHYEREKARFSWIEVTFKHPPLQVRASLEHIVVIRNRQSSAYKWKETLYSVMPGLKITMDKAGLLLLSSPNRVTIGLLSWDGPGKGLRLLLRDTDHFSSQISGTFGQFYQDVVWGPPAAADDSKRTVTVQGHDHSATRELKLDYQEGSPGKEISCWTVVL", "length": 980, "header": "tr|A0A8W4FCE0-1|A0A5G2R7M3_PIG Computationally mapped isoform of Inter-alpha-trypsin inhibitor heavy chain 4 OS=Sus scrofa OX=9823 GN=ITIH4 PE=1 SV=1 CANONICAL=A0A5G2R7M3-1" }, "locus": { "chromosome": "13", "start_pos": 34945703, "end_pos": 34928613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099021.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099021.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076523.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076523.1" } ] } }, { "isoform_ac": "F1SH92-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3/entry#F1SH92-1", "sequence": { "sequence": "MKTLSPTGAYGLLLVLPLLLAVLQSTTAHKNDINIYSLTVDSKVSSRFAHTVVTSRVVNKGSAVQEATFQMELPKKAFITNFSMIIDGVTYPGNIKEKAAAQEQYSAAVARGESAGLVRATGRKTEQFQVAVSVAPAAKVTFELVYEELLARHLGVYELLLKIQPQQLVKHLQMDIHIFEPQGISFLETESTFMTNELAEALTISQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNFIVRYDVNRTVTGGSIQIENGYFVHYFAPEGLSAIPKNVVFVIDTSGSMRGRKIQQTREALIKILGDLGSRDQFNLVSFSGEATQWKKGLLPASAENVEEAKSYAAEIHAQGGTNINDAMLMAVQLLERANREELLPARSVTLIILLTDGDPTVGETNPSKIQKNVREAIDGQHSLFCLGFGFDVSYAFLEKMALENGGLARRIYEDSDSALQLEDFYQEVANPLLRLVAFEYPSNAVEAVTQDNFRLFFKGSELVVAGKLRDQSPDVLSAKVRGQLHMENVTFVMESRVAEQEAEFLSPKYIFHSFMERLWAYLTIQQLLAQTVSASDAEKKALEARALSLSLNYSFVTPLTSMVITKPEGQEQSQVAEKPVENGNRQGNTHSGHSSFQFHSVGDRTSRLTGGSSVDPVFSHRRGWKGQAQGFEKMSYLPPRLGPPGPLQPTRFSHPFSRITLDRVLPEVLSVPDETSHDMDSRIIGATIPPPPARIQAPSVILPLPGQSVDQLCVDLKHSQGPVKLLSDPGQGVEVTGHYEREKARFSWIEVTFKHPPLQVRASLEHIVVIRNRQSSAYKWKETLYSVMPGLKITMDKAGLLLLSSPNRVTIGLLSWDGPGKGLRLLLRDTDHFSSQISGTFGQFYQDVVWGPPAAADDSKRTVTVQGHDHSATRELKLDYQEGSPGKEISCWTVVL", "length": 925, "header": "tr|F1SH92-1|F1SH92_PIG Computationally mapped isoform of Inter-alpha-trypsin inhibitor heavy chain 4 OS=Sus scrofa OX=9823 GN=ITIH4 PE=1 SV=5 CANONICAL=A0A5G2R7M3-1" }, "locus": { "chromosome": "13", "start_pos": 34943863, "end_pos": 34928613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012534.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012534.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012206.5", "url": "https://www.ensembl.org/id/ENSSSCP00000012206.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QN24", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN24" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7M3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7M3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7M3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7M3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "acute-phase response", "id": "GO:0006953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006953", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7M3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3" } ], "pmid": "" }, { "name": "hyaluronan metabolic process", "id": "GO:0030212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030212", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7M3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3" } ], "pmid": "" }, { "name": "response to cytokine", "id": "GO:0034097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034097", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7M3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" }, { "start_pos": 658, "end_pos": 660, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7M3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 988, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7M3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7M3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3" }, { "id": "PS51468", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51468" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VIT", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 225, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R7M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7M3" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 351, "end_pos": 534, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 594, "end_pos": 596 }, { "start_pos": 658, "end_pos": 660 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2REW9-1", "uniprot_ac": "A0A5G2REW9", "uniprot_id": "A0A5G2REW9_PIG", "mass": { "chemical_mass": 31435.0, "monoisotopic_mass": 31435.0 }, "refseq": {}, "gene_names": [ { "name": "SLC35A3", "type": "recommended", "evidence": [ { "id": "A0A5G2REW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REW9" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member A3", "type": "synonym", "evidence": [ { "id": "A0A5G2REW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REW9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REW9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REW9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC35A3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REW9", "locus": { "chromosome": "4", "start_pos": 118103006, "end_pos": 118153159, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006871", "url": "https://www.ensembl.org/id/ENSSSCG00000006871" } ] } } ], "crossref": [ { "id": "A0A5G2REW9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2REW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006871", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006871", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04142", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04142", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A288CG62", "url": "https://www.uniprot.org/uniprotkb/A0A288CG62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A288CG62-1", "url": "https://www.uniprot.org/uniprotkb/A0A288CG62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW08-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ81-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REW9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSANLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRILHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQWPSDSQELEKELSAGSQFVGLMAVLTACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGYNRLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFLGAILVITATFLYGYDPKPAGNPTKA", "length": 284, "header": "tr|A0A5G2REW9-1|A0A5G2REW9_PIG Isoform 1 of Solute carrier family 35 member A3 OS=Sus scrofa OX=9823 GN=SLC35A3 PE=1 SV=1 CANONICAL=A0A5G2REW9-1" }, "isoforms": [ { "isoform_ac": "A0A288CG62-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REW9/entry#A0A288CG62-1", "sequence": { "sequence": "MERPSAERGPPERSRERRSSGPRRKPEHLGDGTAGTRKRLGRTGPAAAAAAAAAGADGAAHQGSRRTRRARQPGAPRGAEPLPPLRAAGGAAREVSLARCWAAAGAGRPVPEALAGAAPGGGGCGRGTDVKPVCLKGTVSKSLRTPEVGVGVDEVTRCRSQGRREECAGWRRKKGLGKGVCQANENGRVCLGAWGVGSRGARGPGGRPFLANGPGAPARCVALWQVPTTRRDPGLKKPQGLQEMEGLPLANEDKTMSANLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRILHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLGKKLGLYQWLSLVILMTGVAFVQWPSDSQELEKELSAGSQFVGLMAVLTACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGYNRLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFLGAILVITATFLYGYDPKPAGNPTKA", "length": 580, "header": "tr|A0A288CG62-1|A0A5G2REW9_PIG Computationally mapped isoform of Solute carrier family 35 member A3 OS=Sus scrofa OX=9823 GN=SLC35A3 PE=1 SV=1 CANONICAL=A0A5G2REW9-1" }, "locus": { "chromosome": "4", "start_pos": 118152960, "end_pos": 118107303, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007524.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007524.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007325.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007325.3" } ] } }, { "isoform_ac": "A0A5G2QW08-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REW9/entry#A0A5G2QW08-1", "sequence": { "sequence": "MSANLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRILHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLGKKLGLYQWLSLVILMTGVAFVQWPSDSQELEKELSAGSQFVGLMAVLTACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGYNRLTWIVVVLQCLFSWSHPCNNSYFPIWL", "length": 269, "header": "tr|A0A5G2QW08-1|A0A5G2REW9_PIG Computationally mapped isoform of Solute carrier family 35 member A3 OS=Sus scrofa OX=9823 GN=SLC35A3 PE=1 SV=1 CANONICAL=A0A5G2REW9-1" }, "locus": { "chromosome": "4", "start_pos": 118125276, "end_pos": 118107337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077281.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077281.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062374.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062374.1" } ] } }, { "isoform_ac": "A0A5G2QZ81-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REW9/entry#A0A5G2QZ81-1", "sequence": { "sequence": "MSANLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRILHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLGKKLGLYQWLSLVILMTGVAFVQWPSDSQELEKELSAGSQFVGLMAVLTACFSSGFAGVYFEKILKETKQSVWIRNIQLVSFFLEPSL", "length": 220, "header": "tr|A0A5G2QZ81-1|A0A5G2REW9_PIG Computationally mapped isoform of Solute carrier family 35 member A3 OS=Sus scrofa OX=9823 GN=SLC35A3 PE=1 SV=1 CANONICAL=A0A5G2REW9-1" }, "locus": { "chromosome": "4", "start_pos": 118125276, "end_pos": 118107365, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067281.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067281.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070201.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070201.1" } ] } }, { "isoform_ac": "A0A5G2REW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REW9/entry#A0A5G2REW9-1", "sequence": { "sequence": "MSANLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRILHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQWPSDSQELEKELSAGSQFVGLMAVLTACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGYNRLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFLGAILVITATFLYGYDPKPAGNPTKA", "length": 284, "header": "tr|A0A5G2REW9-1|A0A5G2REW9_PIG Isoform 1 of Solute carrier family 35 member A3 OS=Sus scrofa OX=9823 GN=SLC35A3 PE=1 SV=1 CANONICAL=A0A5G2REW9-1" }, "locus": { "chromosome": "4", "start_pos": 118125276, "end_pos": 118107303, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083655.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083655.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073241.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073241.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A288CG62", "url": "https://www.uniprot.org/uniprotkb/A0A288CG62" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REW9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REW9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "pyrimidine nucleotide-sugar transmembrane transporter activity", "id": "GO:0015165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REW9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2REW9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 284, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2REW9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2REW9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7W0-1", "uniprot_ac": "A0A5G2R7W0", "uniprot_id": "A0A5G2R7W0_PIG", "mass": { "chemical_mass": 56211.0, "monoisotopic_mass": 56211.0 }, "refseq": {}, "gene_names": [ { "name": "STAMBP", "type": "recommended", "evidence": [ { "id": "A0A5G2R7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ] } ], "protein_names": [ { "name": "STAM-binding protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0/entry#names_and_taxonomy" } ] }, { "name": "Associated molecule with the SH3 domain of STAM", "type": "synonym", "evidence": [ { "id": "A0A5G2R7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization. Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0#function" }, { "database": "UniProtKB", "id": "ARBA00058580", "url": "https://www.uniprot.org/uniprotkb/ARBA00058580#function" }, { "database": "UniProtKB", "id": "A0A480ENI7", "url": "https://www.uniprot.org/uniprotkb/A0A480ENI7#function" }, { "database": "UniProtKB", "id": "F1SLF9", "url": "https://www.uniprot.org/uniprotkb/F1SLF9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "STAMBP", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0", "locus": { "chromosome": "3", "start_pos": 69133978, "end_pos": 69188192, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008300", "url": "https://www.ensembl.org/id/ENSSSCG00000008300" } ] } } ], "crossref": [ { "id": "A0A5G2R7W0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7W0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008300", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008300", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12947", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12947", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12947:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12947:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01398", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01398", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5689901", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689901", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A480ENI7", "url": "https://www.uniprot.org/uniprotkb/A0A480ENI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480ENI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A480ENI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDV8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SLF9", "url": "https://www.uniprot.org/uniprotkb/F1SLF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SLF9-1", "url": "https://www.uniprot.org/uniprotkb/F1SLF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWWGLGAERGLTVTRSGGRECGTCSPLLPAPPAQPSAREFPDGSGAQSGPARPRLPHGPLCCCQESFLVPMSDHGDVSLPPEDRVRALSQIGSAVEVNEDIPPRRYFRSGMEIIRMASIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKTAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYAEYNEEKKREAEELARNIAIQQELEKERQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLDGPLLPGLEKPSLDVSPTAPVISTQPSDCNTTVRPAKPPVVDRSLKPGALSNSGSTPTIDGLRHVVVPEKLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVLIPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFQETGFFRLTDHGLEEISSCRQKGFHPHSKDPPLFCVCIHKVPSAVTCLLKVSIFFFINLSS", "length": 502, "header": "tr|A0A5G2R7W0-1|A0A5G2R7W0_PIG Isoform 1 of STAM-binding protein OS=Sus scrofa OX=9823 GN=STAMBP PE=1 SV=2 CANONICAL=A0A5G2R7W0-1" }, "isoforms": [ { "isoform_ac": "A0A480ENI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0/entry#A0A480ENI7-1", "sequence": { "sequence": "MWWGLGAERGLTVTRSGGRECGTCSPLLPAPPAQPSAREFPDGSGAQSGPARPRLPHGPLCCCQESFLVPMSDHGDVSLPPEDRVRALSQIGSAVEVNEDIPPRRYFRSGMEIIRMASIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKTAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYAEYNEEKKREAEELARNIAIQQELEKERQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLDGPLLPGLEKPSLDVSPTAPVISTQPSDCNTTVRPAKPPVVDRSLKPGALSNSGSTPTIDGLRHVVVPEKLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVLIPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFQETGFFRLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTIIDLR", "length": 494, "header": "tr|A0A480ENI7-1|A0A5G2R7W0_PIG Computationally mapped isoform of STAM-binding protein OS=Sus scrofa OX=9823 GN=STAMBP PE=1 SV=1 CANONICAL=A0A5G2R7W0-1" }, "locus": { "chromosome": "3", "start_pos": 69188125, "end_pos": 69158967, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058744.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058744.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039881.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039881.2" } ] } }, { "isoform_ac": "A0A5G2R7W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0/entry#A0A5G2R7W0-1", "sequence": { "sequence": "MWWGLGAERGLTVTRSGGRECGTCSPLLPAPPAQPSAREFPDGSGAQSGPARPRLPHGPLCCCQESFLVPMSDHGDVSLPPEDRVRALSQIGSAVEVNEDIPPRRYFRSGMEIIRMASIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKTAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYAEYNEEKKREAEELARNIAIQQELEKERQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLDGPLLPGLEKPSLDVSPTAPVISTQPSDCNTTVRPAKPPVVDRSLKPGALSNSGSTPTIDGLRHVVVPEKLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVLIPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFQETGFFRLTDHGLEEISSCRQKGFHPHSKDPPLFCVCIHKVPSAVTCLLKVSIFFFINLSS", "length": 502, "header": "tr|A0A5G2R7W0-1|A0A5G2R7W0_PIG Isoform 1 of STAM-binding protein OS=Sus scrofa OX=9823 GN=STAMBP PE=1 SV=2 CANONICAL=A0A5G2R7W0-1" }, "locus": { "chromosome": "3", "start_pos": 69188125, "end_pos": 69160995, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070377.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070377.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066691.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066691.2" } ] } }, { "isoform_ac": "A0A8W4FDV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0/entry#A0A8W4FDV8-1", "sequence": { "sequence": "MSDHGDVSLPPEDRVRALSQIGSAVEVNEDIPPRRYFRSGMEIIRMASIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKTAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYAEYNEEKTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFQETGFFRLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTIIDLR", "length": 214, "header": "tr|A0A8W4FDV8-1|A0A5G2R7W0_PIG Computationally mapped isoform of STAM-binding protein OS=Sus scrofa OX=9823 GN=STAMBP PE=1 SV=1 CANONICAL=A0A5G2R7W0-1" }, "locus": { "chromosome": "3", "start_pos": 69186266, "end_pos": 69158967, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099088.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099088.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077601.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077601.1" } ] } }, { "isoform_ac": "F1SLF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0/entry#F1SLF9-1", "sequence": { "sequence": "MSDHGDVSLPPEDRVRALSQIGSAVEVNEDIPPRRYFRSGMEIIRMASIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKTAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYAEYNEEKKREAEELARNIAIQQELEKERQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKPSDCNTTVRPAKPPVVDRSLKPGALSNSGSTPTIDGLRHVVVPEKLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVLIPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFQETGFFRLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTIIDLR", "length": 394, "header": "tr|F1SLF9-1|A0A5G2R7W0_PIG Computationally mapped isoform of STAM-binding protein OS=Sus scrofa OX=9823 GN=STAMBP PE=1 SV=2 CANONICAL=A0A5G2R7W0-1" }, "locus": { "chromosome": "3", "start_pos": 69186266, "end_pos": 69158967, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009091.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009091.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008862.3", "url": "https://www.ensembl.org/id/ENSSSCP00000008862.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 280, "start_aa": "Thr", "end_pos": 280, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr280", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SLF9", "url": "https://www.uniprot.org/uniprotkb/F1SLF9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5689901", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689901", "resource": "Reactome", "description": "Metalloprotease DUBs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" }, { "name": "negative regulation of Ras protein signal transduction", "id": "GO:0046580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046580", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" }, { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" }, { "name": "metal-dependent deubiquitinase activity", "id": "GO:0140492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140492", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7W0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7W0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 502, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7W0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7W0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7W0" }, { "id": "PS50249", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MPN", "eco_id": "ECO_0000259", "start_pos": 327, "end_pos": 458, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 280 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 292, "end_pos": 294 }, { "start_pos": 499, "end_pos": 501 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8F6-1", "uniprot_ac": "A0A5G2R8F6", "uniprot_id": "A0A5G2R8F6_PIG", "mass": { "chemical_mass": 71944.0, "monoisotopic_mass": 71944.0 }, "refseq": {}, "gene_names": [ { "name": "ZSCAN29", "type": "recommended", "evidence": [ { "id": "A0A5G2R8F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6" } ] } ], "protein_names": [ { "name": "Zinc finger and SCAN domain containing 29", "type": "synonym", "evidence": [ { "id": "A0A5G2R8F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8F6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8F6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZSCAN29", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6", "locus": { "chromosome": "1", "start_pos": 128097517, "end_pos": 128084050, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004709", "url": "https://www.ensembl.org/id/ENSSSCG00000004709" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004709", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004709", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45935", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45935", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45935:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45935:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47595", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47595", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47595:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47595:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13837", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13837", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZIR7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZIR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZIR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZIR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8F6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAKPTLRGTGTNSETFRQRFRRFHYQEVAGPREAFSQLWQLCCRWLRPEVRTKEQIVELLVLEQFLTILPGEIQNWVQKQCPESGEEAVALVEDLEREPGRPGHSVTVSMKGQEVRLEKMTPLKSSRELLSVLQESVEPQPRGVPKKERARSSDLGPREQMNPQEKLRPFQRSGLPFSKSMVSKLEQGEPWIPDLGSKEKELPRGRHTGDRQLHADLLPSSRERKSRVEQDHWGFEDEKVAGVHWGYEETRTLLAILSQTEFYEALRNCHRNSQVYEAVAERLREYGFLRTLEQCRTKFKGLQKSYRKVKSGHPPETCPFFEEMEALMSAQVIALPSNGLEEAASHSGLVASDAETEEPEQEGWQHEDRGEAMAEESDSDEVGQEATPQDTDNSTTPVLFRSPSGVHWGYEETKTYLAILSETQFYEALRNCHRNSQLYGAVAERLWEHGFLRTPEQCRTKFKSLQTSYRKVKNGQAPETCPFFEEMDALVSAGVAAQPSDGQEEEAGSCPIQTSEAEAEKQAEEADEAIEDSEDDDEDTEVPPEAVTRAPVLFQSPSGFEAGFENEENQKRIFLRKYNYIEHYLQGLKGKFPGILIRVEAVRVNVDQENSGKRSHGREEENQHSQRRV", "length": 630, "header": "tr|A0A5G2R8F6-1|A0A5G2R8F6_PIG Isoform 1 of Zinc finger and SCAN domain containing 29 OS=Sus scrofa OX=9823 GN=ZSCAN29 PE=3 SV=2 CANONICAL=A0A5G2R8F6-1" }, "isoforms": [ { "isoform_ac": "A0A286ZIR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6/entry#A0A286ZIR7-1", "sequence": { "sequence": "MMAKPTLRGTGTNSETFRQRFRRFHYQEVAGPREAFSQLWQLCCRWLRPEVRTKEQIVELLVLEQFLTILPGEIQNWVQKQCPESGEEAVALVEDLEREPGRPGHSDYHFLNPWSPNWSKESHGSQIWAPRRRNSQEAVTQETDNCMLICYHPAEREKAGWNRITGALRMRRWQVYTGAMKRPEHSLQFSVRLSFMRLSETVIETAKCMRLWLSGSGSMASSGPWNSVEPSSKVSRRAIGKSRVATLLRPAPSLKRWKP", "length": 259, "header": "tr|A0A286ZIR7-1|A0A5G2R8F6_PIG Computationally mapped isoform of Zinc finger and SCAN domain containing 29 OS=Sus scrofa OX=9823 GN=ZSCAN29 PE=3 SV=4 CANONICAL=A0A5G2R8F6-1" }, "locus": { "chromosome": "1", "start_pos": 128088601, "end_pos": 128085209, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059846.4", "url": "https://www.ensembl.org/id/ENSSSCT00000059846.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031372.4", "url": "https://www.ensembl.org/id/ENSSSCP00000031372.4" } ] } }, { "isoform_ac": "A0A5G2R8F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6/entry#A0A5G2R8F6-1", "sequence": { "sequence": "MMAKPTLRGTGTNSETFRQRFRRFHYQEVAGPREAFSQLWQLCCRWLRPEVRTKEQIVELLVLEQFLTILPGEIQNWVQKQCPESGEEAVALVEDLEREPGRPGHSVTVSMKGQEVRLEKMTPLKSSRELLSVLQESVEPQPRGVPKKERARSSDLGPREQMNPQEKLRPFQRSGLPFSKSMVSKLEQGEPWIPDLGSKEKELPRGRHTGDRQLHADLLPSSRERKSRVEQDHWGFEDEKVAGVHWGYEETRTLLAILSQTEFYEALRNCHRNSQVYEAVAERLREYGFLRTLEQCRTKFKGLQKSYRKVKSGHPPETCPFFEEMEALMSAQVIALPSNGLEEAASHSGLVASDAETEEPEQEGWQHEDRGEAMAEESDSDEVGQEATPQDTDNSTTPVLFRSPSGVHWGYEETKTYLAILSETQFYEALRNCHRNSQLYGAVAERLWEHGFLRTPEQCRTKFKSLQTSYRKVKNGQAPETCPFFEEMDALVSAGVAAQPSDGQEEEAGSCPIQTSEAEAEKQAEEADEAIEDSEDDDEDTEVPPEAVTRAPVLFQSPSGFEAGFENEENQKRIFLRKYNYIEHYLQGLKGKFPGILIRVEAVRVNVDQENSGKRSHGREEENQHSQRRV", "length": 630, "header": "tr|A0A5G2R8F6-1|A0A5G2R8F6_PIG Isoform 1 of Zinc finger and SCAN domain containing 29 OS=Sus scrofa OX=9823 GN=ZSCAN29 PE=3 SV=2 CANONICAL=A0A5G2R8F6-1" }, "locus": { "chromosome": "1", "start_pos": 128093961, "end_pos": 128085209, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071738.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071738.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066893.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066893.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZIR7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZIR7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8F6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8F6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8F6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8F6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8F6" }, { "id": "PS50804", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50804" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCAN box", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 99, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 394, "end_pos": 396 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7Y0-1", "uniprot_ac": "A0A5G2R7Y0", "uniprot_id": "A0A5G2R7Y0_PIG", "mass": { "chemical_mass": 34261.0, "monoisotopic_mass": 34261.0 }, "refseq": {}, "gene_names": [ { "name": "SLC25A36", "type": "recommended", "evidence": [ { "id": "A0A5G2R7Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0" } ] } ], "protein_names": [ { "name": "Solute carrier family 25 member 36", "type": "synonym", "evidence": [ { "id": "A0A5G2R7Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC25A36", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0", "locus": { "chromosome": "13", "start_pos": 81791891, "end_pos": 81750031, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036855", "url": "https://www.ensembl.org/id/ENSSSCG00000036855" } ] } } ], "crossref": [ { "id": "ENSSSCG00000036855", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036855", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WVMYEQM", "url": "https://omabrowser.org/oma/group/WVMYEQM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR45829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45829:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45829:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "73531", "url": "https://www.rhea-db.org/rhea/73531", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZMD3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZMD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZMD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZMD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B085", "url": "https://www.uniprot.org/uniprotkb/A0A287B085", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B085-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B085-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7Y0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVHLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNGLFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGEKRMGAFECVRKVYQTDGLRGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKIASTMETEEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG", "length": 311, "header": "tr|A0A5G2R7Y0-1|A0A5G2R7Y0_PIG Isoform 1 of Solute carrier family 25 member 36 OS=Sus scrofa OX=9823 GN=SLC25A36 PE=3 SV=2 CANONICAL=A0A5G2R7Y0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZMD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0/entry#A0A286ZMD3-1", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVHLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNGLFDPDSTQVHMISAAMAGHLMLPIRRSLPVEIWTNLNLVLPQSQRPTPFGL", "length": 162, "header": "tr|A0A286ZMD3-1|A0A5G2R7Y0_PIG Computationally mapped isoform of Solute carrier family 25 member 36 OS=Sus scrofa OX=9823 GN=SLC25A36 PE=3 SV=2 CANONICAL=A0A5G2R7Y0-1" }, "locus": { "chromosome": "13", "start_pos": 81783197, "end_pos": 81750233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063584.2", "url": "https://www.ensembl.org/id/ENSSSCT00000063584.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032782.2", "url": "https://www.ensembl.org/id/ENSSSCP00000032782.2" } ] } }, { "isoform_ac": "A0A287B085-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0/entry#A0A287B085-1", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVHLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSSSSYSNSVADTCLIFQLFIKSNIFCCLFKLQGKVEWFI", "length": 132, "header": "tr|A0A287B085-1|A0A5G2R7Y0_PIG Computationally mapped isoform of Solute carrier family 25 member 36 OS=Sus scrofa OX=9823 GN=SLC25A36 PE=3 SV=2 CANONICAL=A0A5G2R7Y0-1" }, "locus": { "chromosome": "13", "start_pos": 81774376, "end_pos": 81750233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039971.2", "url": "https://www.ensembl.org/id/ENSSSCT00000039971.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049626.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049626.2" } ] } }, { "isoform_ac": "A0A5G2R7Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0/entry#A0A5G2R7Y0-1", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVHLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNGLFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGEKRMGAFECVRKVYQTDGLRGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKIASTMETEEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG", "length": 311, "header": "tr|A0A5G2R7Y0-1|A0A5G2R7Y0_PIG Isoform 1 of Solute carrier family 25 member 36 OS=Sus scrofa OX=9823 GN=SLC25A36 PE=3 SV=2 CANONICAL=A0A5G2R7Y0-1" }, "locus": { "chromosome": "13", "start_pos": 81788044, "end_pos": 81750233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088904.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088904.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072431.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072431.2" } ] } }, { "isoform_ac": "A0A8W4FKZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0/entry#A0A8W4FKZ1-1", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVHLNTMAGASVNRVVSPGPLHCLKAIYFAAYSNCKEKLNGLFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGEKRMGAFECVRKVYQTDGLRGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKIASTMETEEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG", "length": 285, "header": "tr|A0A8W4FKZ1-1|A0A5G2R7Y0_PIG Computationally mapped isoform of Solute carrier family 25 member 36 OS=Sus scrofa OX=9823 GN=SLC25A36 PE=3 SV=1 CANONICAL=A0A5G2R7Y0-1" }, "locus": { "chromosome": "13", "start_pos": 81788044, "end_pos": 81750233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098339.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098339.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079577.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079577.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZMD3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZMD3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4ACN9-1", "protein_name": "Solute carrier family 25 member 36", "gene_name": "Slc25a36", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNGVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGEKRMGAFECVRKVYQTDGLRGFYRGMSASYAGISETVIHFVIYESIKQKLLECKTASMMETDEESVKEASDFVRMMLAAATSKTCATTVAYPHEVVRTRLREEGTKYRSFFQTLSLIVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y0", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MU04-1", "protein_name": "Solute carrier family 25 member 36", "gene_name": "SLC25A36", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLSTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNGLFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGEKRMGAFECVRKVYQTDGLRGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKIASTMENEEESVKEVSDFVGMMLAAATSKTCATSIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y0", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P38127-1", "protein_name": "Mitochondrial pyrimidine nucleotide transporter RIM2", "gene_name": "RIM2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPKKSIEEWEEDAIESVPYLASDEKGSNYKEATQIPLNLKQSEIENHPTVKPWVHFVAGGIGGMAGAVVTCPFDLVKTRLQSDIFLKAYKSQAVNISKGSTRPKSINYVIQAGTHFKETLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSINFFTYGTTKDMYAKAFNNGQETPMIHLMAAATAGWATATATNPIWLIKTRVQLDKAGKTSVRQYKNSWDCLKSVIRNEGFTGLYKGLSASYLGSVEGILQWLLYEQMKRLIKERSIEKFGYQAEGTKSTSEKVKEWCQRSGSAGLAKFVASIATYPHEVVRTRLRQTPKENGKRKYTGLVQSFKVIIKEEGLFSMYSGLTPHLMRTVPNSIIMFGTWEIVIRLLS", "length": 377 }, "evidence": [ { "id": "A0A5G2R7Y0", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54Z02-1", "protein_name": "Mitochondrial substrate carrier family protein", "gene_name": "rimA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFPTFINYTTLSVPNSIQIPNNLNNINNIINIQNNNNNINNNNNNNNRKKRSKNALLHFIAGGIGGAAGVICTSPLEVIKTQLQAKNSNLLVKDKPRFVPTTAYSLYHLVKRDGKSGLWKGLGAHLLGVAPARAIHFSSYSFTKSIMNKLGYTDGPILWITSAVSSGAAVAITTSPIWLIKTRMQLQTSLKNFNEGTQYRGMFHCCLSILREEGPLGFYKGLGASLISVSESAFQFVLYEGFKNRIITEKRLKGYENPNELSTSEYLISAGIAKLIAAITTYPHEVVRTRLREQTKPGVKSKYTGVIQGLTLIAREEGIRGLFGGAGPHIIRVVPNSCIMFLTYELVLDIAHGVSLLFDTNHYRQ", "length": 365 }, "evidence": [ { "id": "A0A5G2R7Y0", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5ZKP7-1", "protein_name": "Solute carrier family 25 member 36", "gene_name": "SLC25A36", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVHLNTVNGASVNRVTRVSPGPLHCLKMILQKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNNIFNPDSTQVHMISAGVAGFTAITMTNPIWLVKTRLQLDARNRGEKRMSAFECVRKVYRSDGIKGFYRGMSASYAGISETVIHFVIYESIKRKLLEHKTASAMDSEDESAKEASDFVGMMMAAATSKTCATSIAYPHEVVRTRLREEGTKYRSFFQTLSLLVREEGYGSLYRGLTTHLVRQIPNTAIMMSTYEVVVYLLDG", "length": 313 }, "evidence": [ { "id": "A0A5G2R7Y0", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6DG32-1", "protein_name": "Solute carrier family 25 member 36-A", "gene_name": "slc25a36a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTFYISEVQLSTVNGASVARMAPPGPLHCLKLILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSTSKEKLNNVFDPDSTQVHMLSAGLAGFTAITATNPIWLIKTRLQLDARNRGERRMSAFECVRRVYQSDGLRGFYRGMSASYAGISETVIHFVIYESIKRKLIEHKANSNMDDEDESVKDASDFVGMMLAAATSKTCATSIAYPHEVIRTRLREEGSKYRSFFQTLNMVFREEGYRALYRGLTTHLVRQIPNTAIMMCTYELVVYLLNG", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y0", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7XA87-1", "protein_name": "Folate transporter 1, chloroplastic", "gene_name": "FOLT1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAASWQWENATAGAVAGFATVAAMHSLDVVRTRFQVNDGRGSSLPTYKNTAHAVFTIARLEGLRGLYAGFFPAVIGSTVSWGLYFFFYGRAKQRYARGRDDEKLSPALHLASAAEAGALVCLCTNPIWLVKTRLQLQTPLHQTQPYSGLLDAFRTIVKEEGPRALYKGIVPGLVLVSHGAIQFTAYEELRKIIVDLKERRRKSESTDNLLNSADYAALGGSSKVAAVLLTYPFQVIRARLQQRPSTNGIPRYIDSLHVIRETARYEGLRGFYRGLTANLLKNVPASSITFIVYENVLKLLKQHPTTKD", "length": 308 }, "evidence": [ { "id": "A0A5G2R7Y0", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q922G0-1", "protein_name": "Solute carrier family 25 member 36", "gene_name": "Slc25a36", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKAILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNGVFDPDSTQVHMASAAMAGFTAITATNPIWLIKTRLQLDARTRGEKQMGAFECVRKVYQTDGLRGFYRGMSASYAGISETVIHFVIYESIKQKLLECKTASMMETDEESVKEASDFVRMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLIVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y0", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96CQ1-1", "protein_name": "Solute carrier family 25 member 36", "gene_name": "SLC25A36", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y0", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VQ37-1", "protein_name": "Mitochondrial carrier protein Rim2", "gene_name": "Rim2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAQNTADTLIHLIAGGSAGTVGAVVTCPLEVVKTRLQSSTAFMTPSRLAENAGGGPANGGQSELLRPEQRRKLSTTILRNRSQPQVIGGVRRIMAISHCGISSTTPKSMSIVQCLRHIVQNEGPRALFKGLGPNLVGVAPSRAIYFCTYSQTKNTLNSLGFVERDSPLVHIMSAASAGFVSSTATNPIWFVKTRMQLDYNSKVQMTVRQCIERVYAQGGVAAFYKGITASYFGICETMVHFVIYEFIKSKLLEQRNQRHTDTKGSRDFLEFMMAGAVSKTIASCIAYPHEVARTRLREEGNKYNSFWQTLHTVWKEEGRAGLYRGLATQLVRQIPNTAIMMATYEAVVYVLTRRFNNKSNEFYDF", "length": 365 }, "evidence": [ { "id": "A0A5G2R7Y0", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "pyrimidine nucleotide transmembrane transporter activity", "id": "GO:0015218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015218", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "pyrimidine nucleotide import into mitochondrion", "id": "GO:1990519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990519", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "73531", "name": "", "equation": "UTP(in) + CTP(out) = UTP(out) + CTP(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73531", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73531" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RD19-1", "uniprot_ac": "A0A5G2RD19", "uniprot_id": "A0A5G2RD19_PIG", "mass": { "chemical_mass": 70666.0, "monoisotopic_mass": 70666.0 }, "refseq": { "ac": "XP_003135131", "name": "coiled-coil domain-containing protein 22", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135131" }, "gene_names": [ { "name": "CCDC22", "type": "recommended", "evidence": [ { "id": "A0A5G2RD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" } ] }, { "name": "CCDC22", "type": "synonym", "evidence": [ { "id": "XP_003135131", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135131" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 22", "type": "recommended", "evidence": [ { "id": "A0A5G2RD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 22", "type": "synonym", "evidence": [ { "id": "XP_003135131", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135131" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CCDC22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19", "locus": { "chromosome": "X", "start_pos": 43303864, "end_pos": 43285246, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012297", "url": "https://www.ensembl.org/id/ENSSSCG00000012297" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012297", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012297", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100512878", "url": "https://www.ncbi.nlm.nih.gov/gene/100512878", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008530", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008530", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512878", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512878", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RD19", "url": "https://www.orthodb.org/?gene=A0A5G2RD19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15668", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15668", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15668:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15668:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05667", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05667", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21674", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21674", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003135131", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135131", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZPM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RD19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RD19-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEADRILIHSLRQAGTAVPPDVQTLRAFTTELVVEAVVRCLRVINPAVGSGLSPLLPLAMSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPTDASEDADQPAGDSAILLRAIGSQIRDQLALPWVPPLLRTPKLQHLQGSAPQKPFHASRLAMPDLSSRAEPQEFQASPLLLPAPTQVPQPAARAASLLEHHAVQLCQQTGRDRPGDEDWVHRASRLPAQEDTRAHRQRLQKHLAEHLRQTWGRLGPPPQARDLGELLQAWGAGTRTGTPKGSRFTHSEKFTFHLEPEAQAAQVSDVPTTSRRPEQDTWAAQEQELESLREQLEGVNRNIEEVEANMKTLGISLVQVETECRQSELSTAEREQALRLKSRAVELLPDGAANLAKLQLVVESSAQRVIHLAGQWEKHRVPLLAEYRHLRKLQDCRELESSRRLAEIQELHQSVRAAAEEARRKEEVYKQLMSELVTLPRDVSRPAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFAVTDELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETEMGKKTLSNLEKIREDYRALRQENAGLLGRVREA", "length": 627, "header": "tr|A0A5G2RD19-1|A0A5G2RD19_PIG Isoform 1 of Coiled-coil domain-containing protein 22 OS=Sus scrofa OX=9823 GN=CCDC22 PE=1 SV=1 CANONICAL=A0A5G2RD19-1" }, "isoforms": [ { "isoform_ac": "A0A286ZPM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19/entry#A0A286ZPM3-1", "sequence": { "sequence": "RTPTSRSLISGLAVPPDVQTLRAFTTELVVEAVVRCLRVINPAVGSGLSPLLPLAMSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPTDASEDADQPAGDSAILLRAIGSQIRDQLALPWVPPLLRTPKLQHLQGSAPQKPFHASRLAMPDLSSRAEPQEFQASPLLLPAPTQVPQPAARAASLLEHHAVQLCQQTGRDRPGDEDWVHRASRLPAQEDTRAHRQRLQKHLAEHLRQTWGRLGPPPQARDLGELLQAWGAGTRTGTPKGSRFTHSEKFTFHLEPEAQAAQVSDVPTTSRRPEQDTWAAQEQELESLREQLEGVNRNIEEVEANMKTLGISLVQVETECRQSELSTAEREQALRLKSRAVELLPDGAANLAKLQLVVESSAQRVIHLAGQWEKHRVPLLAEYRHLRKLQDCRELESSRRLAEIQELHQSVRAAAEEARRKEEVYKQLMSELVTLPRDVSRPAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFAVTDELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETEMGKKTLSNLEKIREDYRALRQENAGLLGRVREA", "length": 622, "header": "tr|A0A286ZPM3-1|A0A5G2RD19_PIG Computationally mapped isoform of Coiled-coil domain-containing protein 22 OS=Sus scrofa OX=9823 GN=CCDC22 PE=1 SV=3 CANONICAL=A0A5G2RD19-1" }, "locus": { "chromosome": "X", "start_pos": 43303567, "end_pos": 43286031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045146.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045146.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033545.3", "url": "https://www.ensembl.org/id/ENSSSCP00000033545.3" } ] } }, { "isoform_ac": "A0A5G2RD19-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19/entry#A0A5G2RD19-1", "sequence": { "sequence": "MEEADRILIHSLRQAGTAVPPDVQTLRAFTTELVVEAVVRCLRVINPAVGSGLSPLLPLAMSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPTDASEDADQPAGDSAILLRAIGSQIRDQLALPWVPPLLRTPKLQHLQGSAPQKPFHASRLAMPDLSSRAEPQEFQASPLLLPAPTQVPQPAARAASLLEHHAVQLCQQTGRDRPGDEDWVHRASRLPAQEDTRAHRQRLQKHLAEHLRQTWGRLGPPPQARDLGELLQAWGAGTRTGTPKGSRFTHSEKFTFHLEPEAQAAQVSDVPTTSRRPEQDTWAAQEQELESLREQLEGVNRNIEEVEANMKTLGISLVQVETECRQSELSTAEREQALRLKSRAVELLPDGAANLAKLQLVVESSAQRVIHLAGQWEKHRVPLLAEYRHLRKLQDCRELESSRRLAEIQELHQSVRAAAEEARRKEEVYKQLMSELVTLPRDVSRPAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFAVTDELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETEMGKKTLSNLEKIREDYRALRQENAGLLGRVREA", "length": 627, "header": "tr|A0A5G2RD19-1|A0A5G2RD19_PIG Isoform 1 of Coiled-coil domain-containing protein 22 OS=Sus scrofa OX=9823 GN=CCDC22 PE=1 SV=1 CANONICAL=A0A5G2RD19-1" }, "locus": { "chromosome": "X", "start_pos": 43303567, "end_pos": 43285443, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075087.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075087.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072212.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072212.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPM3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512878", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512878", "resource": "KEGG Pathway" }, { "id": "R-SSC-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "intracellular copper ion homeostasis", "id": "GO:0006878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006878", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" } ], "pmid": "" }, { "name": "positive regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000060", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cullin family protein binding", "id": "GO:0097602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097602", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" }, { "id": "PF21674", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21674" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCDC22 N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 109, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD19" }, { "id": "PF05667", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05667" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCDC22 coiled-coil", "eco_id": "ECO_0000259", "start_pos": 128, "end_pos": 597, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 566, "end_pos": 568 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RF79-1", "uniprot_ac": "A0A5G2RF79", "uniprot_id": "A0A5G2RF79_PIG", "mass": { "chemical_mass": 52785.0, "monoisotopic_mass": 52785.0 }, "refseq": {}, "gene_names": [ { "name": "RCSD1", "type": "recommended", "evidence": [ { "id": "A0A5G2RF79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" } ] } ], "protein_names": [ { "name": "RCSD domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A5G2RF79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RCSD1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79", "locus": { "chromosome": "4", "start_pos": 83324187, "end_pos": 83404102, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006307", "url": "https://www.ensembl.org/id/ENSSSCG00000006307" } ] } } ], "crossref": [ { "id": "A0A5G2RF79", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RF79", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006307", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006307", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152372", "url": "https://www.ncbi.nlm.nih.gov/gene/100152372", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152372", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152372", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEGAETH", "url": "https://omabrowser.org/oma/group/QEGAETH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZSH0", "url": "https://www.orthodb.org/?gene=A0A286ZSH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21669", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21669", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21669:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21669:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15255", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15255", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZSH0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZSH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RF79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RF79-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S269", "url": "https://www.uniprot.org/uniprotkb/F1S269", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S269-1", "url": "https://www.uniprot.org/uniprotkb/F1S269-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKVSTLDLKAEILLICFVHSLFIEGLELLMLRTRADGAVPQPASRARRRPLALCPPQPNPARAGAERRARIASPGPSERARPPPSRHLEDMEERPAETNANVDDSALPSVAQLAGRFREQAAAAKETPASRPTRRKPPCSLSLFPPKVELGQNGEEKSPPTANHPPKMKVKSSPLIEKLQANLAFDPAALLPGASPKSPGLKAMVSPFHSPPSTPSSPGVRSRASEPEEPPVSFDQPPEGSHLPCYNKVRTRGSIKRRPPSRRFRRSQSDCGDLGDFRAVESSQENGAKEENGDEVFPAKGKAPGSPPQSRMSSRTEKPEEKGRAAEKAQQPEKAMGNSEEGAGQRPAQASSPEREDASGSPTEEKPAGGQTEEPSEVKEKAASGEEEPGQRGPDTKGPEEGAGAEETPKKSLPGEVEGGHSSEQETSMEKQDEGTGLEPGCNPGTSHTQPDTSSEVLKTEVGVQRVKNPTSIYEDASSIPGLDQWVKDPALP", "length": 494, "header": "tr|A0A5G2RF79-1|A0A5G2RF79_PIG Isoform 1 of RCSD domain containing 1 OS=Sus scrofa OX=9823 GN=RCSD1 PE=1 SV=1 CANONICAL=A0A5G2RF79-1" }, "isoforms": [ { "isoform_ac": "A0A286ZSH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79/entry#A0A286ZSH0-1", "sequence": { "sequence": "MEKVSTLDLKAEILLICFVHSLFIEGLELLMLRTRADGAVPQPASRARRRPLALCPPQPNPARAGAERRARIASPGPSERARPPPSRHLEDMEERPAETNANVDDSALPSVAQLAGRFREQAAAAKETPASRPTRRKPPCSLSLFPPKVELGQNGEEKSPPTANHPPKMKVKSSPLIEKLQANLAFDPAALLPGASPKSPGLKAMVSPFHSPPSTPSSPGVRSRASEPEEPPVSFDQPPEGSHLPCYNKVRTRGSIKRRPPSRRFRRSQSDCGDLGDFRAVESSQENGAKEENGDEVFPAKGKAPGSPPQSRMSSRTEKPEEKGRAAEKAQQPEKAMGNSEEGAGQRPAQASSPEREDASGSPTEEKPAGGQTEEPSEVKEKAASGEEEPGQRGPDTKGPEEGAGAEETPKKSLPGEVEGGHSSEQETSMEKQDEGTGLEPGCNPGTSHTQPDTSSEVLKTEDNTPVQEIKM", "length": 472, "header": "tr|A0A286ZSH0-1|A0A5G2RF79_PIG Computationally mapped isoform of RCSD domain containing 1 OS=Sus scrofa OX=9823 GN=RCSD1 PE=1 SV=1 CANONICAL=A0A5G2RF79-1" }, "locus": { "chromosome": "4", "start_pos": 83404083, "end_pos": 83326114, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045228.1", "url": "https://www.ensembl.org/id/ENSSSCT00000045228.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034518.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034518.1" } ] } }, { "isoform_ac": "A0A5G2RF79-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79/entry#A0A5G2RF79-1", "sequence": { "sequence": "MEKVSTLDLKAEILLICFVHSLFIEGLELLMLRTRADGAVPQPASRARRRPLALCPPQPNPARAGAERRARIASPGPSERARPPPSRHLEDMEERPAETNANVDDSALPSVAQLAGRFREQAAAAKETPASRPTRRKPPCSLSLFPPKVELGQNGEEKSPPTANHPPKMKVKSSPLIEKLQANLAFDPAALLPGASPKSPGLKAMVSPFHSPPSTPSSPGVRSRASEPEEPPVSFDQPPEGSHLPCYNKVRTRGSIKRRPPSRRFRRSQSDCGDLGDFRAVESSQENGAKEENGDEVFPAKGKAPGSPPQSRMSSRTEKPEEKGRAAEKAQQPEKAMGNSEEGAGQRPAQASSPEREDASGSPTEEKPAGGQTEEPSEVKEKAASGEEEPGQRGPDTKGPEEGAGAEETPKKSLPGEVEGGHSSEQETSMEKQDEGTGLEPGCNPGTSHTQPDTSSEVLKTEVGVQRVKNPTSIYEDASSIPGLDQWVKDPALP", "length": 494, "header": "tr|A0A5G2RF79-1|A0A5G2RF79_PIG Isoform 1 of RCSD domain containing 1 OS=Sus scrofa OX=9823 GN=RCSD1 PE=1 SV=1 CANONICAL=A0A5G2RF79-1" }, "locus": { "chromosome": "4", "start_pos": 83404083, "end_pos": 83333890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087342.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087342.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073407.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073407.1" } ] } }, { "isoform_ac": "F1S269-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79/entry#F1S269-1", "sequence": { "sequence": "CQERPAETNANVDDSALPSVAQLAGRFREQAAAAKEKSPPTANHPPKMKVKSSPLIEKLQANLAFDPAALLPGASPKSPGLKAMVSPFHSPPSTPSSPGVRSRASEPEEPPVSFDQPPEGSHLPCYNKVRTRGSIKRRPPSRRFRRSQSDCGDLGDFRAVESSQENGAKEENGDEVFPAKGKAPGSPPQSRMSSRTEKPEEKGRAAEKAQQPEKAMGNSEEGAGQRPAQASSPEREDASGSPTEEKPAGGQTEEPSEVKEKAASGEEEPGQRGPDTKGPEEGAGAEETPKKSLPGEVEGGHSSEQETSMEKQDEGTGLEPGCNPGTSHTQPDTSSEVLKTEVGVQRVKNPTSIYEDASSIPGLDQWVKDPALP", "length": 373, "header": "tr|F1S269-1|A0A5G2RF79_PIG Computationally mapped isoform of RCSD domain containing 1 OS=Sus scrofa OX=9823 GN=RCSD1 PE=1 SV=5 CANONICAL=A0A5G2RF79-1" }, "locus": { "chromosome": "4", "start_pos": 83348190, "end_pos": 83333890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006912.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006912.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006724.5", "url": "https://www.ensembl.org/id/ENSSSCP00000006724.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 215, "start_aa": "Thr", "end_pos": 215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr215", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZSH0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSH0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152372", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152372", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5YCC4-1", "protein_name": "RCSD domain containing 1", "gene_name": "Rcsd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYMRPRTLKIAPLSKHLPHREDADNEDQERPSETNSNVDSSAQPSVAQLAGRFREQAAVARETPASKPTRRKPPCSLPLFPPKVELGQNGEEKSPSSTSHPPKIKVKSSPLIEKLQANLAFDPAALLPGASPKSPGLKAMVSPFHSPPSTPSSPGIRSHPGEAEEVPVSFDQPPEGTHLPSYNKVRTRGSIKRRPPSRRFRRSQSDCGDLRDYRAVEPSQENGAREENGDDVFPSKSKDPGSPQPNQEAGADRVEGTLRSTEKPRRRNTCSSTEKPEELVGTLEEANAGAKAGQTPDTASQGHPEVQEPSQTCSPETENGCGSPREETAPGEHTDTGKATEGTASEERVTEEEDGLGQKSPDANIPEDEVVRGKVPQTSSGEAEGTTVPEPEAKQKEEAPLEPSGSPGADHSAGEASNEIQSENAVSTEDIPVEDTRM", "length": 438 }, "evidence": [ { "id": "A0A5G2RF79", "url": "https://omabrowser.org/oma/group/A0A5G2RF79/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MMB8-1", "protein_name": "RCSD domain containing 1", "gene_name": "RCSD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEERPAQTNAIVDDSAPPSVAQLAGRFREQAAAAKETPASKPTRRKPPCSLPLFPSKVELGQNGEEKSLPSANHPPKVKVKSSPLIEKLQANLVFDPAALLPGASPKSPGFKAMVSPFHSPPSTPSSPGVRSRPSEPEEVPVSFDQPPEGSHLPCYNKVRTRGSIKRRPPSRRFRRSQSDCGELGEFRAVEPSQENGAKEESGDEVFPAKSKAPGSPPLRRTSSRTEKLEEKSRAVGEAQEPEKIAGGSEEGAGQHPARASSSEAEDGCGSPKEERPAGEQAEEPTEVKERVASEEEEPRQSSQDTKELEEGAVEEEPPQPPPGGGAGGHSPEQGTSEEKQDEGASLKPGCSPNSGAHAQPDTSSEVPRTEDNTPVQDTKM", "length": 381 }, "evidence": [ { "id": "A0A5G2RF79", "url": "https://omabrowser.org/oma/group/A0A5G2RF79/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UZA1-1", "protein_name": "CapZ-interacting protein", "gene_name": "Rcsd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEERPSETNSNVDSSAQPSVAQLAGRFREHAAVARETPASKPTRRKPPCSLPLFPPKVELGQNGEEKSPSGASHPPKIKVKSSPLIEKLQANLAFDPAALLPGASPKSPGLKAIVSPFHSPPSTPSSPGIRSHPSEAEEVPVSFDQPPEGTHLPSYNKVRTRGSIKRRPPSRRFRRSQSDCGDFRDYRAVEPSQENGAREENGDDVFASKSKDPGSPQLNQEAMADGVEGTPWSAEKPRRRNTCNSTEKPEELVRTPEEANAGEKVGQNPDTASQGHPEVQAPSQTGSPEAENGCGSPREETTPGEHTDTGKATEGTASEERVADEDRLGQKSPDANMPEEEGVVREKAPQTSSGKAEGTTIAEPDTKQKEEAPLEPSCSPGADHAAGEITSEIQNEKAVSMDDIPIEDTRM", "length": 412 }, "evidence": [ { "id": "A0A5G2RF79", "url": "https://omabrowser.org/oma/group/A0A5G2RF79/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6JBY9-1", "protein_name": "CapZ-interacting protein", "gene_name": "RCSD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEERPAETNANVDNSASPSVAQLAGRFREQAAAAKETPASKPTRRKPPCSLPLFPPKVDLGQNGEEKSPPNASHPPKFKVKSSPLIEKLQANLTFDPAALLPGASPKSPGLKAMVSPFHSPPSTPSSPGVRSRPSEAEEVPVSFDQPPEGSHLPCYNKVRTRGSIKRRPPSRRFRRSQSDCGELGDFRAVESSQQNGAKEEDGDEVLPSKSKAPGSPLSSEGAAGEGVRTLGPAEKPPLRRSPSRTEKQEEDRATEEAKNGEKARRSSEEVDGQHPAQEEVPESPQTSGPEAENRCGSPREEKPAGEEAEMEKATEVKGERVQNEEVGPEHDSQETKKLEEGAAVKETPHSPPGGVKGGDVPKQEKGKEKQQEGAVLEPGCSPQTGPAQLETSSEVQSEPAVPKPEDDTPVQDTKM", "length": 416 }, "evidence": [ { "id": "A0A5G2RF79", "url": "https://omabrowser.org/oma/group/A0A5G2RF79/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" } ], "pmid": "" }, { "name": "WASH complex", "id": "GO:0071203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071203", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate binding", "id": "GO:1901981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" } ], "pmid": "" }, { "name": "retromer complex binding", "id": "GO:1905394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905394", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein localization to endosome", "id": "GO:0036010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036010", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" } ], "pmid": "" }, { "name": "cellular hyperosmotic response", "id": "GO:0071474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071474", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF79", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RF79-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 494, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RF79-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RF79" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RF79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" }, { "id": "PF15255", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15255" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM21/CAPZIP", "eco_id": "ECO_0000259", "start_pos": 166, "end_pos": 288, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RF79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF79" }, { "id": "PF05177", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RCSD", "eco_id": "ECO_0000259", "start_pos": 308, "end_pos": 384, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 215 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R996-1", "uniprot_ac": "A0A5G2R996", "uniprot_id": "A0A5G2R996_PIG", "mass": { "chemical_mass": 326537.0, "monoisotopic_mass": 326537.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "KASH domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996", "locus": {} } ], "crossref": [ { "id": "A0A5G2R996", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R996", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004082", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004082", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSSSCG00000031744", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031744", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00176", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00176", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RINFFAR", "url": "https://omabrowser.org/oma/group/RINFFAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR14514", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14514", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14514:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14514:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00435", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00435", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10541", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10541", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZWB9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZWB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QA52", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QA52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QA52-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QA52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R996-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAK2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S7X0", "url": "https://www.uniprot.org/uniprotkb/F1S7X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S7X0-1", "url": "https://www.uniprot.org/uniprotkb/F1S7X0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFPQELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDGELLPATSAHPSVVMDIAYYQALSAERLQTEAARIPPSTLPSRELYEPGLEPSATAKLDDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAVEMKLSESLEHGRSPESQMAEHQALMDEILMLQEEIRELQAALAEELVSEAPESDPAEQLALQSTLTVLAERMSTIKMKAAGKRQLLEGTAQEKEETDADLAATQSPGVQEWLAQARTAWTHQRQSSLQQQKELEQELAEQKSLLRSVASRGEEILTQHSAAETAGGVGEKPDVLSQELGMEGEKAPAEDQMRVKWESLHQEFSTKQKLLQNVLEQEQEPVLYRRPNRLLSGVPLYKGDGQAQDKAAVTSLLDGLNQAFEEVSSQGGGTKRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEETETCLFNQETLAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADHKYIILQKLANVFEQPVAEQIEAIQQAEDGLKELDAGITELKRRGDKLQIEQPSVQELSKLQDMYDELMVTIGSRRSGLNQNLALKSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVLQETQNHTELMAQASAVLKRAHKRGVELEYILETWSHLDQDHRELRRQLEMVESSIPSVGLVEESEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLMSVSCSDLESQLNQLGEHWLNDTNKVAKELHRLETILKHWTRYQRESSDLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAKSTLKSSVLSTGNQLLRLKKVDTAALRSELSHIDSQWNGLLTNIPAVQEKLHQLQMDKLPSRHAISEVMAWISLMENVIQKDEEHIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGLLESWSEYENNVQCMKTWFETQEKRLKQQHRIGDQASVQNSLKDCQDLEDLIKAKEKEVEKIEQNGLALIQNKKEEVSGIVKSTLQELNQTWANLDHKAGQLKILLKSVLDQWSHHKVAFDEINSFLTEARYSLSRFRLLTGSLEAVQVQVDNLQKLQDDLEKQENSLEKFGSVTNQLLKECHPPVTETLTNTLKEVTMRWNNLLEEMAEQLHSSKALLQLWQRYKDYSKQCASAVQQQEARAKELLKAATSKDIADDEVATWIQDCNDLLRGLGTVNDSLFVLHELGEQLKQQVDASAASAIQSDQLSLSQQLSALEQALCKQQTTLQAGVLDYETFTKSLEALEAWIEEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSLVPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIADGQHLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPTSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASVHLEEQKKKLAFLLKDWEKCENGIADSLEKLRTFKKRLSQPLPDHHEELHAELMRCKELENAVGSWTDDLAQLALLKDTLCAYISPDDISILNERMELLQRQWEELCHQLSLRRQQVSERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEDMIEKLRKDYQEEIAIAQENKIQLQQMGERLARASHESKASEIEYKLGKINDRWQHLLDLMAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSHFEDWLKVSERIAAFPSSSGVLYTVAKEELKKFEAFQRQVHETLTQLELINKQYRRLARENRTDSACCLKQMVHEGNQRWDDLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHSKIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDQELELAEAEALSDLHWRDTPADSVLSPPPSSNPSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAVSRTLPSEDEEGQEEKDFYLRGAVGLSGDPSALESQIRQLGKALDDSRFPMLPAETALRSKTPPGPELDSSYRGYMKLLGECSGSIDSVKRLEHKLAEEEQHFPGFVNLNSTESQTAGVIDRWELLQAQALSKELRMKQNPQRRQQFDSDLNSLLAWLRETEEELEQLQRLQLSTDIQSIALQIQKLKELQKAVDHRKAIILSINLCSSEFTQTGSEESQDLQDRLSQMNGRWDHVCSLLEEWRGLLQDALMQCQDFHEMSHGLLLMLENIDRRKNEIVPIDSHLDSETLQDHHKQLTQMKRELLESQLKVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKESEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQRTPRGKCSLSQPGPSVNSPHSRSIKGGSDSSLSEDRPARSGRSFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 2850, "header": "tr|A0A5G2R996-1|A0A5G2R996_PIG Isoform 1 of KASH domain-containing protein OS=Sus scrofa OX=9823 GN= PE=1 SV=2 CANONICAL=A0A5G2R996-1" }, "isoforms": [ { "isoform_ac": "A0A286ZWB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996/entry#A0A286ZWB9-1", "sequence": { "sequence": "MLKTAMAYQDFEGRCLVPDPGPDPSILSWYFSLIPPNAEINSLFLPFCSQGGGTKRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEETETCLFNQETLAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADHKYIILQKLANVFEQPVAEQIEAIQQAEDGLKELDAGITELKRRGDKLQIEQPSVQELSKLQDMYDELMVTIGSRRSGLNQNLALKSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVLQETQNHTELMAQASAVLKRAHKRGVELEYILETWSHLDQDHRELRRQLEMVESSIPSVGLVEESEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLMSVIFQRGRCQIHPEIICSEHWKSAPSIKESGHSCPALRAVTHR", "length": 483, "header": "tr|A0A286ZWB9-1|A0A5G2R996_PIG Computationally mapped isoform of KASH domain-containing protein OS=Sus scrofa OX=9823 GN= PE=1 SV=1 CANONICAL=A0A5G2R996-1" }, "locus": { "chromosome": "1", "start_pos": 14091905, "end_pos": 14070069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050808.1", "url": "https://www.ensembl.org/id/ENSSSCT00000050808.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035989.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035989.1" } ] } }, { "isoform_ac": "A0A5G2QA52-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996/entry#A0A5G2QA52-1", "sequence": { "sequence": "MRKQRHREGIHLPVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSHFEDWLKVSERIAAFPSSSGVLYTVAKEELKKFEAFQRQVHETLTQLELINKQYRRLARENRTDSACCLKQMVHEGNQRWDDLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHSKIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDQELELAEAEALSDLHWRDTPADSVLSPPPSSNPSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAVSRTLPSEDEEGQEEKDFYLRGAVGLSGDPSALESQIRQLGKALDDSRFPMLPAETALRSKTPPGPELDSSYRGYMKLLGECSGSIDSVKRLEHKLAEEEQHFPGFVNLNSTESQTAGVIDRWELLQAQALSKELRMKQNPQRRQQFDSDLNSLLAWLRETEEELEQLQRLQLSTDIQSIALQIQKLKELQKAVDHRKAIILSINLCSSEFTQTGSEESQDLQDRLSQMNGRWDHVCSLLEEWRGLLQDALMQCQDFHEMSHGLLLMLENIDRRKNEIVPIDSHLDSETLQDHHKQLTQMKRELLESQLKVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKESEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQRTPRGKCSLSQPGPSVNSPHSRSIKGGSDSSLSEDRPARSGRSFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 934, "header": "tr|A0A5G2QA52-1|A0A5G2QA52_PIG Computationally mapped isoform of KASH domain-containing protein OS=Sus scrofa OX=9823 GN= PE=1 SV=1 CANONICAL=A0A5G2R996-1" }, "locus": { "chromosome": "1", "start_pos": 14200964, "end_pos": 14156215, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089249.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089249.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060238.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060238.1" } ] } }, { "isoform_ac": "A0A5G2R996-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996/entry#A0A5G2R996-1", "sequence": { "sequence": "MFPQELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDGELLPATSAHPSVVMDIAYYQALSAERLQTEAARIPPSTLPSRELYEPGLEPSATAKLDDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAVEMKLSESLEHGRSPESQMAEHQALMDEILMLQEEIRELQAALAEELVSEAPESDPAEQLALQSTLTVLAERMSTIKMKAAGKRQLLEGTAQEKEETDADLAATQSPGVQEWLAQARTAWTHQRQSSLQQQKELEQELAEQKSLLRSVASRGEEILTQHSAAETAGGVGEKPDVLSQELGMEGEKAPAEDQMRVKWESLHQEFSTKQKLLQNVLEQEQEPVLYRRPNRLLSGVPLYKGDGQAQDKAAVTSLLDGLNQAFEEVSSQGGGTKRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEETETCLFNQETLAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADHKYIILQKLANVFEQPVAEQIEAIQQAEDGLKELDAGITELKRRGDKLQIEQPSVQELSKLQDMYDELMVTIGSRRSGLNQNLALKSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVLQETQNHTELMAQASAVLKRAHKRGVELEYILETWSHLDQDHRELRRQLEMVESSIPSVGLVEESEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLMSVSCSDLESQLNQLGEHWLNDTNKVAKELHRLETILKHWTRYQRESSDLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAKSTLKSSVLSTGNQLLRLKKVDTAALRSELSHIDSQWNGLLTNIPAVQEKLHQLQMDKLPSRHAISEVMAWISLMENVIQKDEEHIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGLLESWSEYENNVQCMKTWFETQEKRLKQQHRIGDQASVQNSLKDCQDLEDLIKAKEKEVEKIEQNGLALIQNKKEEVSGIVKSTLQELNQTWANLDHKAGQLKILLKSVLDQWSHHKVAFDEINSFLTEARYSLSRFRLLTGSLEAVQVQVDNLQKLQDDLEKQENSLEKFGSVTNQLLKECHPPVTETLTNTLKEVTMRWNNLLEEMAEQLHSSKALLQLWQRYKDYSKQCASAVQQQEARAKELLKAATSKDIADDEVATWIQDCNDLLRGLGTVNDSLFVLHELGEQLKQQVDASAASAIQSDQLSLSQQLSALEQALCKQQTTLQAGVLDYETFTKSLEALEAWIEEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSLVPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIADGQHLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPTSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASVHLEEQKKKLAFLLKDWEKCENGIADSLEKLRTFKKRLSQPLPDHHEELHAELMRCKELENAVGSWTDDLAQLALLKDTLCAYISPDDISILNERMELLQRQWEELCHQLSLRRQQVSERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEDMIEKLRKDYQEEIAIAQENKIQLQQMGERLARASHESKASEIEYKLGKINDRWQHLLDLMAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSHFEDWLKVSERIAAFPSSSGVLYTVAKEELKKFEAFQRQVHETLTQLELINKQYRRLARENRTDSACCLKQMVHEGNQRWDDLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHSKIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDQELELAEAEALSDLHWRDTPADSVLSPPPSSNPSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAVSRTLPSEDEEGQEEKDFYLRGAVGLSGDPSALESQIRQLGKALDDSRFPMLPAETALRSKTPPGPELDSSYRGYMKLLGECSGSIDSVKRLEHKLAEEEQHFPGFVNLNSTESQTAGVIDRWELLQAQALSKELRMKQNPQRRQQFDSDLNSLLAWLRETEEELEQLQRLQLSTDIQSIALQIQKLKELQKAVDHRKAIILSINLCSSEFTQTGSEESQDLQDRLSQMNGRWDHVCSLLEEWRGLLQDALMQCQDFHEMSHGLLLMLENIDRRKNEIVPIDSHLDSETLQDHHKQLTQMKRELLESQLKVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKESEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQRTPRGKCSLSQPGPSVNSPHSRSIKGGSDSSLSEDRPARSGRSFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 2850, "header": "tr|A0A5G2R996-1|A0A5G2R996_PIG Isoform 1 of KASH domain-containing protein OS=Sus scrofa OX=9823 GN= PE=1 SV=2 CANONICAL=A0A5G2R996-1" }, "locus": { "chromosome": "1", "start_pos": 14200964, "end_pos": 14028882, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082300.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082300.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070694.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070694.2" } ] } }, { "isoform_ac": "A0A8W4FAK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996/entry#A0A8W4FAK2-1", "sequence": { "sequence": "MLTMKAKHATMLLTVTEVEGLAEGTEDLDGELLPATSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTEASVNQDIAYYQALSAERLQTEAARIPPSTLPSRELYEPGLEPSATAKLDDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAVEMKLSESLEHGRSPESQMAEHQALMDEILMLQEEIRELQAALAEELVSEAPESDPAEQLALQSTLTVLAERMSTIKMKAAGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDHWLLSTKATLDIALGTPKEPMDMEAQLVDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTQGQPPGAAEGAA", "length": 367, "header": "tr|A0A8W4FAK2-1|A0A5G2R996_PIG Computationally mapped isoform of KASH domain-containing protein OS=Sus scrofa OX=9823 GN= PE=1 SV=1 CANONICAL=A0A5G2R996-1" }, "locus": { "chromosome": "1", "start_pos": 14052317, "end_pos": 14028957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092158.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092158.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076426.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076426.1" } ] } }, { "isoform_ac": "F1S7X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996/entry#F1S7X0-1", "sequence": { "sequence": "MVVAEDPCAPRMAEDGCADADLPDCNCDVTRVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSHFEDWLKVSERIAAFPSSSGVLYTVAKEELKKFEAFQRQVHETLTQLELINKQYRRLARENRTDSACCLKQMVHEGNQRWDDLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHSKIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDQELELAEAEALSDLHWRDTPADSVLSPPPSSNPSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAVSRTLPSEDEEGQEEKDFYLRGAVGLSDVMIPESPEAYIKLTESAIRNTSGDPSALESQIRQLGKALDDSRFPMLPAETALRSKTPPGPELDSSYRGYMKLLGECSGSIDSVKRLEHKLAEEEQHFPGFVNLNSTESQTAGVIDRWELLQAQALSKELRMKQNPQRRQQFDSDLNSLLAWLRETEEELEQLQRLQLSTDIQSIALQIQKLKELQKAVDHRKAIILSINLCSSEFTQTGSEESQDLQDRLSQMNGRWDHVCSLLEEWRGLLQDALMQCQDFHEMSHGLLLMLENIDRRKNEIVPIDSHLDSETLQDHHKQLTQMKRELLESQLKVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKESEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQRTPRGKCSLSQPGPSVNSPHSRSIKGGSDSSLSEDRPARSGRSFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 975, "header": "tr|F1S7X0-1|A0A5G2R996_PIG Computationally mapped isoform of KASH domain-containing protein OS=Sus scrofa OX=9823 GN= PE=1 SV=4 CANONICAL=A0A5G2R996-1" }, "locus": { "chromosome": "1", "start_pos": 14200964, "end_pos": 14151553, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004511.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004511.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004409.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004409.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2740, "start_aa": "Thr", "end_pos": 2740, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2740", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S7X0", "url": "https://www.uniprot.org/uniprotkb/F1S7X0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" } ], "pmid": "" }, { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" } ], "pmid": "" }, { "name": "cytoskeleton-nuclear membrane anchor activity", "id": "GO:0140444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140444", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of cilium assembly", "id": "GO:1902017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" } ], "pmid": "" }, { "name": "nuclear migration", "id": "GO:0007097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007097", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R996", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1024, "end_pos": 1026, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1053, "end_pos": 1055, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1161, "end_pos": 1163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1350, "end_pos": 1352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1946, "end_pos": 1948, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2123, "end_pos": 2125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2212, "end_pos": 2214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2461, "end_pos": 2463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 715, "end_pos": 717, "annotation": "n_glycosylation_sequon" }, { "start_pos": 831, "end_pos": 833, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R996-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 2850, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R996-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R996" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R996" }, { "id": "PS51049", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51049" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KASH", "eco_id": "ECO_0000259", "start_pos": 2791, "end_pos": 2850, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 2740 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1024, "end_pos": 1026 }, { "start_pos": 1053, "end_pos": 1055 }, { "start_pos": 1161, "end_pos": 1163 }, { "start_pos": 1350, "end_pos": 1352 }, { "start_pos": 1946, "end_pos": 1948 }, { "start_pos": 2123, "end_pos": 2125 }, { "start_pos": 2212, "end_pos": 2214 }, { "start_pos": 2461, "end_pos": 2463 }, { "start_pos": 715, "end_pos": 717 }, { "start_pos": 831, "end_pos": 833 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RFR0-1", "uniprot_ac": "A0A5G2RFR0", "uniprot_id": "A0A5G2RFR0_PIG", "mass": { "chemical_mass": 56603.0, "monoisotopic_mass": 56603.0 }, "refseq": {}, "gene_names": [ { "name": "KRT15", "type": "recommended", "evidence": [ { "id": "A0A5G2RFR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" } ] } ], "protein_names": [ { "name": "Keratin 15", "type": "synonym", "evidence": [ { "id": "A0A5G2RFR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KRT15", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0", "locus": { "chromosome": "12", "start_pos": 21130241, "end_pos": 21124705, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017444", "url": "https://www.ensembl.org/id/ENSSSCG00000017444" } ] } } ], "crossref": [ { "id": "A0A5G2RFR0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017444", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017444", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EARYCAQ", "url": "https://omabrowser.org/oma/group/EARYCAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF164", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF164", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZYN0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0K2", "url": "https://www.uniprot.org/uniprotkb/F1S0K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0K2-1", "url": "https://www.uniprot.org/uniprotkb/F1S0K2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTTFLQTSSSTFGGGSTRGGSLLAGVGGFGGGSLYGGGGSRSISVSSSRFVSSGSGGGFGGGAGSGLGGGFGGGLGGGLGGGFGGGFAGSFGGGFGDFGGGNGGLLAGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYKKQSPSSPERDYSPYFKTMEELRDKIRAAAIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLTKTDLEMQIESLNEELAYLKKNHEEEMKEFSNQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAIAEKNRRDAEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTVQGLEIELQSQLSMKAGLESSLAETECRYATQLQQIQGLIGGLETQLSELRSEMECQNQEYKMLWTSRRGWSRRSPPTAACWRARTPGWPALAPEKPPWEVAAAKSASTSRSQWMGRWFLPEREKSKGSAQERCPPPSPGRVDAWPEGPEELMPGPAFGGSSSRGPSSPSWALCLLSPITPSSFLISFGAGR", "length": 526, "header": "tr|A0A5G2RFR0-1|A0A5G2RFR0_PIG Isoform 1 of Keratin 15 OS=Sus scrofa OX=9823 GN=KRT15 PE=1 SV=1 CANONICAL=A0A5G2RFR0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZYN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0/entry#A0A286ZYN0-1", "sequence": { "sequence": "MSTTFLQTSSSTFGGGSTRGGSLLAGVGGFGGGSLYGGGGSRSISVSSSRFVSSGSGGGFGGGAGSGLGGGFGGGLGGGLGGGFGGGFAGSFGGGFGDFGGGNGGLLAGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYKKQSPSSPERDYSPYFKTMEELRDKIRAAAIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLTKTDLEMQIESLNEELAYLKKNHEEEMKEFSNQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAIAEKNRRDAEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTVQGLEIELQSQLSMKAGLESSLAETECRYATQLQQIQGLIGGLETQLSELRSEMECQNQEYKILLEGQDARQGTSLGGGGGKVRINVEESVDGKVVSSRKREI", "length": 437, "header": "tr|A0A286ZYN0-1|A0A5G2RFR0_PIG Computationally mapped isoform of Keratin 15 OS=Sus scrofa OX=9823 GN=KRT15 PE=1 SV=1 CANONICAL=A0A5G2RFR0-1" }, "locus": { "chromosome": "12", "start_pos": 21129963, "end_pos": 21124783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037374.2", "url": "https://www.ensembl.org/id/ENSSSCT00000037374.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036811.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036811.1" } ] } }, { "isoform_ac": "A0A5G2RFR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0/entry#A0A5G2RFR0-1", "sequence": { "sequence": "MSTTFLQTSSSTFGGGSTRGGSLLAGVGGFGGGSLYGGGGSRSISVSSSRFVSSGSGGGFGGGAGSGLGGGFGGGLGGGLGGGFGGGFAGSFGGGFGDFGGGNGGLLAGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYKKQSPSSPERDYSPYFKTMEELRDKIRAAAIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLTKTDLEMQIESLNEELAYLKKNHEEEMKEFSNQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAIAEKNRRDAEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTVQGLEIELQSQLSMKAGLESSLAETECRYATQLQQIQGLIGGLETQLSELRSEMECQNQEYKMLWTSRRGWSRRSPPTAACWRARTPGWPALAPEKPPWEVAAAKSASTSRSQWMGRWFLPEREKSKGSAQERCPPPSPGRVDAWPEGPEELMPGPAFGGSSSRGPSSPSWALCLLSPITPSSFLISFGAGR", "length": 526, "header": "tr|A0A5G2RFR0-1|A0A5G2RFR0_PIG Isoform 1 of Keratin 15 OS=Sus scrofa OX=9823 GN=KRT15 PE=1 SV=1 CANONICAL=A0A5G2RFR0-1" }, "locus": { "chromosome": "12", "start_pos": 21130162, "end_pos": 21124783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070254.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070254.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073697.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073697.1" } ] } }, { "isoform_ac": "F1S0K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0/entry#F1S0K2-1", "sequence": { "sequence": "MSTTFLQTSSSTFGGGSTRGGSLLAGVGGFGGGSLYGGGGSRSISVSSSRFVSSGSGGGFGGGAGSGLGGGFGGGLGGGLGGGFGGGFAGSFGGGFGDFGGGNGGLLAGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYKKQSPSSPERDYSPYFKTMEELRDKIRAAAIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLTKTDLEMQIESLNEELAYLKKNHEEEMKEFSNQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAIAEKNRRDAEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTVQGLEIELQSQLSMKAGLESSLAETECRYATQLQQIQGLIGGLETQLSELRSEMECQNQEYKILLEGQDARMAGIGTREASLGGGGGKVRINVEESVDGKVVSSRKREI", "length": 443, "header": "tr|F1S0K2-1|A0A5G2RFR0_PIG Computationally mapped isoform of Keratin 15 OS=Sus scrofa OX=9823 GN=KRT15 PE=1 SV=2 CANONICAL=A0A5G2RFR0-1" }, "locus": { "chromosome": "12", "start_pos": 21129963, "end_pos": 21124783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018990.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018990.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018485.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018485.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 514, "start_aa": "Thr", "end_pos": 514, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr514", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0K2", "url": "https://www.uniprot.org/uniprotkb/F1S0K2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-SSC-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QGJ8-1", "protein_name": "Keratin, type I cytoskeletal 15 isoform X1", "gene_name": "Krt15", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATTFLQTSSTFGGGSTRGGSLRAGGGGFGGGSLYGGGGSRSISASSARFVSSGAGGGYGGGMSCGFGGGAGSGFGGAFGGGFGGGFGDFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEQANTELEVKIRDWYQKQSPASPERDYSHYFKTMEEIRDKILAATIDNSRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLARTDLEMQIEHLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEKNRRDAEAWFFSKTEELNKEVASNTEMIQSSKTEITDLRRTMQGLEIELQSQLSMKAGLENSLAEVECRYATQLQQIQGLISSLESQLSELRCEMEAQNQEYNMLLDIKTRLEQEIATYRNLLEGQDAKMAGIGVREASLGGGSGGGSSSSNFHISVEESVDGKVVSSRKREI", "length": 457 }, "evidence": [ { "id": "A0A5G2RFR0", "url": "https://omabrowser.org/oma/group/A0A5G2RFR0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B0UYS0-1", "protein_name": "Keratin, type I cytoskeletal 15", "gene_name": "krt15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSFSSRSYVSSGGGFGGGSLRGASLGGMSSSSMMGGGSRISSMRAGSVYGGAGGRGVRISSAAGGGGGAGFGFGGGAGGGGGFGFGGGAGGGFGGGDMDLNVTVNEKATMQNLNDRLATYLDKVRSLEKANADLELKIRQFLESKTSPAARDYSAYQATIKDLQDKIQDATRVNGGVYLAVDNAKLAADDFKTKYENELTMRQSVEADIAGLKRLLDELTLARSDLEMQIEGLKEELIFLKKNHEEELAAMRSQMSGSVNVEVDAAPQVDLNHVMAEIREQYENVAAKNQRDLENWFQTKSETLTKEVAASTETIQVSKTELTELRRTLQGLEIELQSELSKKASLEGTLADTEARFSRQLMNLQTQVTNLEEQIVQLRADMDRQGQEYKMLLDIKTRLEMEIAEYRRLLDGGASSMISTGGGGGGGSSSTSSSSTKSITVKTIVEDIVDGQVVSSSKK", "length": 460 }, "evidence": [ { "id": "A0A5G2RFR0", "url": "https://omabrowser.org/oma/group/A0A5G2RFR0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P19012-1", "protein_name": "Keratin, type I cytoskeletal 15", "gene_name": "KRT15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTTFLQTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGIAIREASSGGGGSSSNFHINVEESVDGQVVSSHKREI", "length": 456 }, "evidence": [ { "id": "A0A5G2RFR0", "url": "https://omabrowser.org/oma/group/A0A5G2RFR0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61414-1", "protein_name": "Keratin, type I cytoskeletal 15", "gene_name": "Krt15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTFLQTSSTFGGSSTRGASLRAGGGSFGGGSLYGGGGSRSISASSARFVSSGAGGGFGGGMSCGFGGGFGGGFGGGFGGGFGDFGGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEQANTELEVKIRDWYQKQSPASPDRDYSHYFKTMEEIRDKILAATIDNSRVVLEIDNARLAADDFRLKYENELTLRQGVEADINGLRRVLDELTLARTDLEMQIEQLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTLQGLEIELQSQLSMKAGLENSLAEVECRYATQLQQIQGVITGLETQLSELRCEMEAQNQEYNMLLDIKTRLEQEIATYRNLLEGQDAKMAGIGVREGSSGGGGSSSSSSNFHISVEESVDGKVVSSRKREI", "length": 452 }, "evidence": [ { "id": "A0A5G2RFR0", "url": "https://omabrowser.org/oma/group/A0A5G2RFR0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" } ], "pmid": "" }, { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" } ], "pmid": "" }, { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" } ], "pmid": "" }, { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" } ], "pmid": "" }, { "name": "morphogenesis of an epithelium", "id": "GO:0002009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFR0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RFR0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 526, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RFR0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFR0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RFR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFR0" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 111, "end_pos": 398, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 514 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RGG2-1", "uniprot_ac": "A0A5G2RGG2", "uniprot_id": "A0A5G2RGG2_PIG", "mass": { "chemical_mass": 100919.0, "monoisotopic_mass": 100919.0 }, "refseq": { "ac": "XP_020957357", "name": "TBC domain-containing protein kinase-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957357" }, "gene_names": [ { "name": "TBCK", "type": "recommended", "evidence": [ { "id": "A0A5G2RGG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" } ] }, { "name": "TBCK", "type": "synonym", "evidence": [ { "id": "XP_020957357", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957357" } ] } ], "protein_names": [ { "name": "TBC domain-containing protein kinase-like protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RGG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2/entry#names_and_taxonomy" } ] }, { "name": "TBC domain-containing protein kinase-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020957357", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957357" } ] } ], "function": [ { "annotation": "Component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction. Also involved in the modulation of mTOR signaling and expression of mTOR complex components. Involved in the control of actin-cytoskeleton organization.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCP2#function" }, { "database": "UniProtKB", "id": "ARBA00058226", "url": "https://www.uniprot.org/uniprotkb/ARBA00058226#function" }, { "database": "UniProtKB", "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2#function" }, { "database": "UniProtKB", "id": "A0A286ZZQ2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZQ2#function" }, { "database": "UniProtKB", "id": "A0A287B2H3", "url": "https://www.uniprot.org/uniprotkb/A0A287B2H3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TBCK", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2", "locus": { "chromosome": "8", "start_pos": 115699941, "end_pos": 115476956, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021784", "url": "https://www.ensembl.org/id/ENSSSCG00000021784" } ] } } ], "crossref": [ { "id": "A0A5G2RGG2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000021784", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000021784", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01525", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01525", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100738532", "url": "https://www.ncbi.nlm.nih.gov/gene/100738532", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100738532", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738532", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THTDRQI", "url": "https://omabrowser.org/oma/group/THTDRQI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RGG2", "url": "https://www.orthodb.org/?gene=A0A5G2RGG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957:SF168", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957:SF168", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24345", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24345", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24345:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24345:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020957357", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957357", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZZQ2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A974", "url": "https://www.uniprot.org/uniprotkb/A0A287A974", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A974-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A974-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2H3", "url": "https://www.uniprot.org/uniprotkb/A0A287B2H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1F3A5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1F3A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1F3A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1F3A5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCEQSLEDLLRERKPVSYPKVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGHVKLAKFGLYHMTAYGDDVDFPIGYPSYLAPEVIAQGIFKTSDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTIIVLAEEHGCLDIIKELPENVTHLLKKCLTFHPSKRPTPDELMQDKVFSEVSPLYTPFTKPASLFSSSLRCADLTLPEDISQLCKDINSDYLAERSIEEVYYLWCLAGGDLEKELMNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIRERDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKSASDSSGVRSSTPYFSTECPDPPKTDLSRESIPLNDLKSEVSPRISAEDLIDLCELTVTGHFKTPTKKTKSSKPKLLVVDIRNSEDFIRGHISGSINIPFITAFTAEGELTQGPYTAMLQSFRGKVIVIVGHVAKHTAEFAAHLVKMKYPRICILDGGINKIKPTGLLTVPSPQI", "length": 893, "header": "tr|A0A5G2RGG2-1|A0A5G2RGG2_PIG Isoform 1 of TBC domain-containing protein kinase-like protein OS=Sus scrofa OX=9823 GN=TBCK PE=3 SV=2 CANONICAL=A0A5G2RGG2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2/entry#A0A286ZZQ2-1", "sequence": { "sequence": "MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCEQSLEDLLRERKPVRYPSYLAPEVIAQGIFKTSDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTIIVLAEEHGCLDIIKELPENVTHLLKKCLTFHPSKRPTPDELMQDKVFSEVSPLYTPFTKPASLFSSSLRCADLTLPEDISQLCKDINSDYLAERSIEEVYYLWCLAGGDLEKELMNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIRERDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKSASDSSGVRSSTPYFSTECPDPPKTDLSRESIPLNDLKSEVSPRISAEDLIDLCELTVTGHFKTPTKKTKSSKPKLLVVDIRNSEDFIRGHISGSINIPFITAFTAEGELTQGPYTAMLQSFRGKVIVIVGHVAKHTAEFAAHLVKMKYPRICILDGGINKIKPTGLLTVPSPQI", "length": 830, "header": "tr|A0A286ZZQ2-1|A0A5G2RGG2_PIG Computationally mapped isoform of TBC domain-containing protein kinase-like protein OS=Sus scrofa OX=9823 GN=TBCK PE=3 SV=3 CANONICAL=A0A5G2RGG2-1" }, "locus": { "chromosome": "8", "start_pos": 115698159, "end_pos": 115482069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041750.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041750.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037125.3", "url": "https://www.ensembl.org/id/ENSSSCP00000037125.3" } ] } }, { "isoform_ac": "A0A287A974-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2/entry#A0A287A974-1", "sequence": { "sequence": "MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCEQSLEDLLRERKPVSYPKVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGHVKLAKFGLYHMTAYGDDVDFPIGYPSYLAPEVIAQGIFKTSDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTIIVLAEEHGCLDIIKELPENVTHLLKKCLTFHPSKRPTPDELMQDKVFSEVSPLYTPFTKPASLFSSSLRCADLTLPEDISQLCKDINSDYLAERSIEEVYYLWCLAGGDLEKELMNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIRERDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKSASDSSGVRSSTPYFSTECPDPPKTDLSRESIPLNDLKSEVSPRISAEDLIDLCELTVTGHFKTPTKKTKSSKPKLLVVDIRNSEDFIRGHISGSINIPFITAFTAEGELTQGPYTAMLQSFRGKVIVIVGHVAKHTAEFAAHLVKMKYPRICILDGGINKIKPTGLLTVPSPQI", "length": 876, "header": "tr|A0A287A974-1|A0A5G2RGG2_PIG Computationally mapped isoform of TBC domain-containing protein kinase-like protein OS=Sus scrofa OX=9823 GN=TBCK PE=3 SV=3 CANONICAL=A0A5G2RGG2-1" }, "locus": { "chromosome": "8", "start_pos": 115698159, "end_pos": 115482069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055701.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055701.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040556.3", "url": "https://www.ensembl.org/id/ENSSSCP00000040556.3" } ] } }, { "isoform_ac": "A0A287B2H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2/entry#A0A287B2H3-1", "sequence": { "sequence": "MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCEQSLEDLLRERKPVSYPKVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGHVKLAKFGLYHMTAYGDDVDFPIGYPSYLAPEVIAQGIFKTSDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTIIVLAEEHGCLDIIKELPENVTHLLKKCLTFHPSKRPTPDELMQDKVFSEVSPLYTPFTKPASLFSSSLRCADLTLPEDISQLCKDINSDYLAERSIEEVYYLWCLAGGDLEKELMNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIRERDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKSASDSSGVRSSTPYFSTECPDPPKTDLVFLFEVIFLAASTFHSSLHSLQKGSLPRALTLPCSRASEERSLSLWGMWQSTQQSLQLIL", "length": 805, "header": "tr|A0A287B2H3-1|A0A287B2H3_PIG Computationally mapped isoform of TBC domain-containing protein kinase-like protein OS=Sus scrofa OX=9823 GN=TBCK PE=3 SV=2 CANONICAL=A0A5G2RGG2-1" }, "locus": { "chromosome": "8", "start_pos": 115698067, "end_pos": 115482069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048474.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048474.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050303.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050303.2" } ] } }, { "isoform_ac": "A0A5G2RCP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2/entry#A0A5G2RCP2-1", "sequence": { "sequence": "MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCEQSLEDLLRERKPVSYPKVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGHVKLAKFGLYHMTAYGDDVDFPIGYPSYLAPEVIAQGIFKTSDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTIIVLAEEHGCLDIIKELPENVTHLLKKCLTFHPSKRPTPDELMQDKVFSEVSPLYTPFTKPASLFSSSLRCADLTLPEDISQLCKDINSDYLAERSIEEVYYLWCLAGGDLEKELMNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIRERDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKSASDSSGVRSSTPYFSTECPDPPKTDLSRESIPLNDLKSEVSPRISAEDLIDLCELTVTGHFKTPTKKTKSSKPKLLVVDIRNSEDFIHVASFPLKGHVVEA", "length": 820, "header": "tr|A0A5G2RCP2-1|A0A5G2RGG2_PIG Computationally mapped isoform of TBC domain-containing protein kinase-like protein OS=Sus scrofa OX=9823 GN=TBCK PE=3 SV=1 CANONICAL=A0A5G2RGG2-1" }, "locus": { "chromosome": "8", "start_pos": 115663142, "end_pos": 115482069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084268.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084268.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072037.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072037.1" } ] } }, { "isoform_ac": "A0A5G2RGG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2/entry#A0A5G2RGG2-1", "sequence": { "sequence": "MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCEQSLEDLLRERKPVSYPKVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGHVKLAKFGLYHMTAYGDDVDFPIGYPSYLAPEVIAQGIFKTSDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTIIVLAEEHGCLDIIKELPENVTHLLKKCLTFHPSKRPTPDELMQDKVFSEVSPLYTPFTKPASLFSSSLRCADLTLPEDISQLCKDINSDYLAERSIEEVYYLWCLAGGDLEKELMNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIRERDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKSASDSSGVRSSTPYFSTECPDPPKTDLSRESIPLNDLKSEVSPRISAEDLIDLCELTVTGHFKTPTKKTKSSKPKLLVVDIRNSEDFIRGHISGSINIPFITAFTAEGELTQGPYTAMLQSFRGKVIVIVGHVAKHTAEFAAHLVKMKYPRICILDGGINKIKPTGLLTVPSPQI", "length": 893, "header": "tr|A0A5G2RGG2-1|A0A5G2RGG2_PIG Isoform 1 of TBC domain-containing protein kinase-like protein OS=Sus scrofa OX=9823 GN=TBCK PE=3 SV=2 CANONICAL=A0A5G2RGG2-1" }, "locus": { "chromosome": "8", "start_pos": 115698159, "end_pos": 115482069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079081.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079081.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074083.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074083.2" } ] } }, { "isoform_ac": "A0A8D1F3A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2/entry#A0A8D1F3A5-1", "sequence": { "sequence": "MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCEQSLEDLLRERKPVSYPKVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGHVKLAKFGLYHMTAYGDDVDFPIGSYYFLT", "length": 158, "header": "tr|A0A8D1F3A5-1|A0A5G2RGG2_PIG Computationally mapped isoform of TBC domain-containing protein kinase-like protein OS=Sus scrofa OX=9823 GN=TBCK PE=3 SV=1 CANONICAL=A0A5G2RGG2-1" }, "locus": { "chromosome": "8", "start_pos": 115538272, "end_pos": 115482069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073486.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073486.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069938.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069938.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCP2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100738532", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738532", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ALH8-1", "protein_name": "TBC domain-containing protein kinase-like protein", "gene_name": "Tbck", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQVLKTITHPRLCQYVDISRGKHERLVVVAEHCERSLEDLLRERRPASHSAVLCIAYEVLEGLQYLNKHGIVHRALSPHNILLDRKGHIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIFKSTDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLGCVDDTLIVLAEEHGCLDIIKELPENALSILKKCLTFHPPKRPTPDELMKDQVFSEVSPLYTPFIKPASLFSSSLRCADLTLPEDISDVCKDIDDDYLAERSIEEVYYLWCLAGGDLEKELINKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSSLPHSNSNNELSAAASLPLIIRERDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMISFHDPELSNHLNEIGFIPDVIYFIKFPTDVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESVNLFCWTPKSATYRQHAQPPRPASESSAVRSSSAPYFSAECTDPPKTDLSRESIPLSDLKSEVSPRISAEDLIDLCELTVTGHFKTPTKKTKSSKPKLLVVDIRNSEDFLRGHIAGSINIPFSAAFTAEGELSQGPYTTMLHSFKGKVIVIVGHVAKQTSEFAAHLVKMKYPRVCILDGGINKIKPTGLLTVPSPQI", "length": 891 }, "evidence": [ { "id": "A0A5G2RGG2", "url": "https://omabrowser.org/oma/group/A0A5G2RGG2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BM85-1", "protein_name": "TBC domain-containing protein kinase-like protein", "gene_name": "Tbck", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCERSLEDLLRERKPVSHSTVLCIAYEVLEGLHYLNKHGIVHRALSPHNILLDRKGHIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIPKTTDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDVSERVKFLLTLGCVDDTIIVLAEEHGCLDIIKELPENVINILKKCLTFHPSKRPTPDELMKDQVFSEVSPLYTPFIKPASLFSSSLRCADLTLPEDISDLCKDIDNDYLAERSIEEVYYLWCLAGGDLEKELINKEIIRSKPPVCTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIRERDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESVNLFCWTPKSATYRQHAQPPKPASESSVVRSSAPYFSAECTDPPKTDLSRESIPLSDLKSEVSPRISAEDLIDLCELTVTGHFKTPTKKTKSSKPKLLVVDIRNSEDFVRGHIAGSINIPFSAAFTAEGELSQGPYTTMLHNFKGKVIVVVGHVAKQTAEFAAHLVKMKYPRVCILDGGINKIRPTGLLTVPSPQI", "length": 893 }, "evidence": [ { "id": "A0A5G2RGG2", "url": "https://omabrowser.org/oma/group/A0A5G2RGG2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TEA7-1", "protein_name": "TBC domain-containing protein kinase-like protein", "gene_name": "TBCK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCERSLEDLLRERKPVSCSTVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKGHIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIFKTTDHMPSKKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTLIVLAEEHGCLDIIKELPETVIDLLNKCLTFHPSKRPTPDQLMKDKVFSEVSPLYTPFTKPASLFSSSLRCADLTLPEDISQLCKDINNDYLAERSIEEVYYLWCLAGGDLEKELVNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIREKDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKPSSDSSGGRSSAPYFSAECPDPPKTDLSRESIPLNDLKSEVSPRISAEDLIDLCELTVTGHFKTPSKKTKSSKPKLLVVDIRNSEDFIRGHISGSINIPFSAAFTAEGELTQGPYTAMLQNFKGKVIVIVGHVAKHTAEFAAHLVKMKYPRICILDGGINKIKPTGLLTIPSPQI", "length": 893 }, "evidence": [ { "id": "A0A5G2RGG2", "url": "https://omabrowser.org/oma/group/A0A5G2RGG2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W4F8-1", "protein_name": "TBC domain-containing protein kinase-like protein", "gene_name": "Dmel\\CG4041", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGTRERERECRLCAVTFFAKLHPGDVCGSNGLPLTPNSIAILGRAQKLKELQDEHLCQYLDVIRGKHERTIVVSEYLGLSLEDYAMRHPPLAIAQILRIFYQVACGINVLSRHHLVAHNVEPKHILLSSDGQRVKLFNYGLHHMTKGGAYVPFPIGNIRYMAPERLLGLNGNVKSDVWSLALVMVELILQIELWPKLKLSNVVRKILAFGKSNGALEKIAREHQCHERYVQMDQRLRQLLESCLSVLPKRRPLPGELLEHPIFEEVLLDLKKQKMQPLSPETEHLPLLLRCPLSQIYHLWQLAGGDVQAELKKEGLIRSEAPILGLPQIVRLSGASVCPGRSQAQLMDDRVVPLRLKALLQRLSGLPAAVYFPLLHSPRFPAHFARELQELPLVIREKDIEYQFQRVRLFARLLQGYPHTAEQLQREAAVDVPPLLRGPIWAALLEVVPNGSYAKIDKFTSTSTDRQIEVDIPRCHQYDELLSSPDGHRKLRRLLKAWVTAHPQYVYWQGLDSLTAPFLYLNFNNEELAFLSLFKFIPKYLQWFFLKDNSAVIKEYLSKFSQLTAFHEPLLAQHLASISFIPELFAIPWFLTMFSHVFPLHKILHLWDKLMLGDSSYPLFIGIAILRQLRSTLLTSGFNECILLFSDLPDIVMDGCVLESQKMYEATPKSITHRQHALRLQPPQALDIGVADVELKHLQQEQCPRISAKDVQFLLDNSPAELALIDLRSVVEFGRVHVPHSINIPFATVQLGEQRLEALQVPQLEAQLRGKIVVCVSNIHQHSVEFSHFLVACGVQRTCILHKGFNVLHSIEPNILISN", "length": 819 }, "evidence": [ { "id": "A0A5G2RGG2", "url": "https://omabrowser.org/oma/group/A0A5G2RGG2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" } ], "pmid": "" }, { "name": "regulation of TOR signaling", "id": "GO:0032006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032006", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RGG2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 893, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RGG2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGG2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RGG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 273, "start_aa": "Met", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RGG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 466, "end_pos": 651, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RGG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGG2" }, { "id": "PS50206", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50206" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rhodanese", "eco_id": "ECO_0000259", "start_pos": 790, "end_pos": 889, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 245, "end_pos": 247 }, { "start_pos": 651, "end_pos": 653 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RDT7-1", "uniprot_ac": "A0A5G2RDT7", "uniprot_id": "A0A5G2RDT7_PIG", "mass": { "chemical_mass": 26010.0, "monoisotopic_mass": 26010.0 }, "refseq": { "ac": "XP_020949321", "name": "RING finger protein 166", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949321" }, "gene_names": [ { "name": "RNF166", "type": "recommended", "evidence": [ { "id": "A0A5G2RDT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7" } ] }, { "name": "RNF166", "type": "synonym", "evidence": [ { "id": "XP_020949321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949321" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RNF166", "type": "recommended", "evidence": [ { "id": "A0A5G2RDT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A5G2RDT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7/entry#names_and_taxonomy" } ] }, { "name": "RING finger protein 166", "type": "synonym", "evidence": [ { "id": "XP_020949321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949321" }, { "id": "A0A5G2RDT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase RNF166", "type": "synonym", "evidence": [ { "id": "A0A5G2RDT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RNF166", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7", "locus": { "chromosome": "6", "start_pos": 982995, "end_pos": 976980, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034455", "url": "https://www.ensembl.org/id/ENSSSCG00000034455" } ] } } ], "crossref": [ { "id": "ENSSSCG00000034455", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034455", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16549", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16549", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110260882", "url": "https://www.ncbi.nlm.nih.gov/gene/110260882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110260882", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110260882", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHTFCGD", "url": "https://omabrowser.org/oma/group/AHTFCGD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RDT7", "url": "https://www.orthodb.org/?gene=A0A5G2RDT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46016", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46016", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46016:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46016:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020949321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949321", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A9W7", "url": "https://www.uniprot.org/uniprotkb/A0A287A9W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A9W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A9W7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QU38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QU38-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMFRSLVASAQQRQPPGGPAGGDSGLEAQYSCPICLEVYHRPVAIGSCGHTFCGECLQPCLQVPSPLCPLCRLPFDPKKVDKATHVEKQLSSYKAPCRGCSKKVTLAKMRVHVASCVKVQEQMASCPKFVPVVPTSQPIPSAVPNRSTFTCPYCGARNLDQQELVRHCVDNHRSDPNRVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVDYSIDEEAAFQAALALSLSEN", "length": 237, "header": "tr|A0A5G2RDT7-1|A0A5G2RDT7_PIG Isoform 1 of E3 ubiquitin-protein ligase RNF166 OS=Sus scrofa OX=9823 GN=RNF166 PE=4 SV=2 CANONICAL=A0A5G2RDT7-1" }, "isoforms": [ { "isoform_ac": "A0A287A9W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7/entry#A0A287A9W7-1", "sequence": { "sequence": "MAMFRSLVASAQQRQPPGGPAGGDSGLEAQYSCPICLEVYHRPVAIGSCGHTFCGECLQPCLQVPSPLCPLCRLPFDPKKVDKATHVEKQLSSYKAPCRGCSKKVTLAKMRVHVASCVKVQEQMASCPKFVPVVPTSQPIPRCAPSARPCPGVTPATRAPTSCSTCSTGTSSPMTPSWTTASMRKPPSRPPWPCLSPRTEGAAAPALASRDRAHQPPGARACPGPRLTAAGGEAAPSHRPGSC", "length": 243, "header": "tr|A0A287A9W7-1|A0A5G2RDT7_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase RNF166 OS=Sus scrofa OX=9823 GN=RNF166 PE=4 SV=2 CANONICAL=A0A5G2RDT7-1" }, "locus": { "chromosome": "6", "start_pos": 982200, "end_pos": 977058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054320.2", "url": "https://www.ensembl.org/id/ENSSSCT00000054320.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040800.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040800.2" } ] } }, { "isoform_ac": "A0A5G2QU38-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7/entry#A0A5G2QU38-1", "sequence": { "sequence": "MAMFRSLVASAQQRQPPGGPAGGDSGLEAQYSCPICLEVQEQMASCPKFVPVVPTSQPIPSAVPNRSTFTCPYCGARNLDQQELVRHCVDNHRSDPNRVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVDYSIDEEAAFQAALALSLSEN", "length": 156, "header": "tr|A0A5G2QU38-1|A0A5G2RDT7_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase RNF166 OS=Sus scrofa OX=9823 GN=RNF166 PE=4 SV=1 CANONICAL=A0A5G2RDT7-1" }, "locus": { "chromosome": "6", "start_pos": 982067, "end_pos": 977058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083941.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083941.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068451.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068451.1" } ] } }, { "isoform_ac": "A0A5G2RDT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7/entry#A0A5G2RDT7-1", "sequence": { "sequence": "MAMFRSLVASAQQRQPPGGPAGGDSGLEAQYSCPICLEVYHRPVAIGSCGHTFCGECLQPCLQVPSPLCPLCRLPFDPKKVDKATHVEKQLSSYKAPCRGCSKKVTLAKMRVHVASCVKVQEQMASCPKFVPVVPTSQPIPSAVPNRSTFTCPYCGARNLDQQELVRHCVDNHRSDPNRVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVDYSIDEEAAFQAALALSLSEN", "length": 237, "header": "tr|A0A5G2RDT7-1|A0A5G2RDT7_PIG Isoform 1 of E3 ubiquitin-protein ligase RNF166 OS=Sus scrofa OX=9823 GN=RNF166 PE=4 SV=2 CANONICAL=A0A5G2RDT7-1" }, "locus": { "chromosome": "6", "start_pos": 982067, "end_pos": 977058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076795.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076795.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068951.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068951.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QU38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QU38" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110260882", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110260882", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7FEA4-1", "protein_name": "E3 ubiquitin-protein ligase RNF166", "gene_name": "rnf166", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMAMFRSFVSAAQLRQHQQQNGAAAAAPGESLESQFSCPICLEVYHKPVSIASCAHTFCGDCLQPCLQVTSPLCPLCRMPFDPKKVDKSSSVEKQLSSYKAPCRGCSKKVTLVKMRSHISSCTKVQEQMANCPKFMPVVPTSQPIPSNIPNRSTFVCPYCGARNLDQQELVKHCMENHRNDPNKVVCPVCSAMPWGDPSYKSSNFLQHLLHRHKFSYDTFVDYSIDEEAALQAALTLSLSEN", "length": 242 }, "evidence": [ { "id": "A0A5G2RDT7", "url": "https://omabrowser.org/oma/group/A0A5G2RDT7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3U9F6-1", "protein_name": "E3 ubiquitin-protein ligase RNF166", "gene_name": "Rnf166", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMFRSLVASAQQRQPPAGPAGGDSGLEAQFSCPICLEVYHRPVAIGSCGHTFCGECLQPCLQVPSPLCPLCRLPFDPKKVDKATHVEKQLSSYKAPCRGCNKKVTLAKMRAHISSCLKVQEQMANCPKFVPVVPTSQPIPSNIPNRSTFACPYCGARNLDQQELVKHCVESHRSDPNRVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVDYSIDEEAAFQAALALSLSEN", "length": 237 }, "evidence": [ { "id": "A0A5G2RDT7", "url": "https://omabrowser.org/oma/group/A0A5G2RDT7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5F3B2-1", "protein_name": "E3 ubiquitin-protein ligase RNF166", "gene_name": "RNF166", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFRSLLVAAAQRPQAPGPGPPRPPPPAGPAAEALEAQFSCPICLEVFHRAVGIAGCGHTFCGECLQPCLQVPSPLCPLCRMPFDPKKVEKASSVEKQLSSYKAPCRGCSKKVTLAKMRSHVSSCAKVQEQMANCPKFVPVVPTSQPIPSNIPNRSTFVCPYCGARNLDQQELVKHCMENHRNDPNKVVCPVCSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVDYNIDEEAALQAALALSLSEN", "length": 244 }, "evidence": [ { "id": "A0A5G2RDT7", "url": "https://omabrowser.org/oma/group/A0A5G2RDT7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6J1I7-1", "protein_name": "E3 ubiquitin-protein ligase RNF166", "gene_name": "Rnf166", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMFRSLVASAQQRQPPAGPAGGDSGLEAQFSCPICLEVYHRPVAIGSCGHTFCGECLQPCLQVPSPLCPLCRLPFDPKKVDKATHVEKQLSSYKAPCRGCNKKVTLAKMRAHISSCLKVQEQMANCPKFVPVVPTSQPIPSNIPNRSTFACPYCGARNLDQQELVKHCVESHRSDPNRVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVDYSIDEEAAFQAALALSLSEN", "length": 237 }, "evidence": [ { "id": "A0A5G2RDT7", "url": "https://omabrowser.org/oma/group/A0A5G2RDT7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96A37-1", "protein_name": "E3 ubiquitin-protein ligase RNF166", "gene_name": "RNF166", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMFRSLVASAQQRQPPAGPAGGDSGLEAQYTCPICLEVYHRPVAIGSCGHTFCGECLQPCLQVPSPLCPLCRLPFDPKKVDKATHVEKQLSSYKAPCRGCNKKVTLAKMRVHISSCLKVQEQMANCPKFVPVVPTSQPIPSNIPNRSTFACPYCGARNLDQQELVKHCVESHRSDPNRVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVDYSIDEEAAFQAALALSLSEN", "length": 237 }, "evidence": [ { "id": "A0A5G2RDT7", "url": "https://omabrowser.org/oma/group/A0A5G2RDT7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RDT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7" }, { "id": "PS51803", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51803" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2HC RNF-type", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 117, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RDT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDT7" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 73, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8K5-1", "uniprot_ac": "A0A5G2R8K5", "uniprot_id": "A0A5G2R8K5_PIG", "mass": { "chemical_mass": 25617.0, "monoisotopic_mass": 25617.0 }, "refseq": {}, "gene_names": [ { "name": "LCN5", "type": "recommended", "evidence": [ { "id": "A0A5G2R8K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K5" } ] } ], "protein_names": [ { "name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R8K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LCN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K5", "locus": {} } ], "crossref": [ { "id": "A0A5G2R8K5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8K5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005834", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005834", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HALYEED", "url": "https://omabrowser.org/oma/group/HALYEED/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11430", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11430", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11430:SF71", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11430:SF71", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AC59", "url": "https://www.uniprot.org/uniprotkb/A0A287AC59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AC59-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AC59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVZ8", "url": "https://www.uniprot.org/uniprotkb/F1RVZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVZ8-1", "url": "https://www.uniprot.org/uniprotkb/F1RVZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGKALAGLLGLLVVLVASAEEMGLRDFNATQFSGLWYEIALASNLEPQTPPQLKKMGAVLVEREGPYLTLTSVSDHINRCVKETTQAVKGDAPGKFKFPKEPGNKDVTVVATDYRTYAIVNVAFQKGRTAHSVLKLYSEPLGALPSPRPAWPCGGHPQPGEGAGAASVALASAQAPAAKGTPPGQAGTWNTTRKSWPTSSWRPRSAGCPRPACSCSSRTVSVRAAGSGRPSPSPQVTILSCPQ", "length": 244, "header": "tr|A0A5G2R8K5-1|A0A5G2R8K5_PIG Isoform 1 of Lipocalin/cytosolic fatty-acid binding domain-containing protein OS=Sus scrofa OX=9823 GN=LCN5 PE=1 SV=1 CANONICAL=A0A5G2R8K5-1" }, "isoforms": [ { "isoform_ac": "A0A287AC59-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K5/entry#A0A287AC59-1", "sequence": { "sequence": "MRGKALAGLLGLLVVLVASAEEMGLRDFNATQFSGLWYEIALASNLEPQTPPQLKKMGAVLVEREGPYLTLTSVSDHINRCVKETTQAVKGDAPGKFKFPKEPGNKDVTVVATDYRTYAIVNVAFQKGRTAHSVLKLYSRDMEHNEKVMAHFLLEASERGLSTASVQLLLKDLTCVNLLR", "length": 180, "header": "tr|A0A287AC59-1|A0A5G2R8K5_PIG Computationally mapped isoform of Lipocalin/cytosolic fatty-acid binding domain-containing protein OS=Sus scrofa OX=9823 GN=LCN5 PE=1 SV=2 CANONICAL=A0A5G2R8K5-1" }, "locus": { "chromosome": "AEMK02000682.1", "start_pos": 1040666, "end_pos": 1038720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059454.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059454.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041402.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041402.2" } ] } }, { "isoform_ac": "A0A5G2R8K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K5/entry#A0A5G2R8K5-1", "sequence": { "sequence": "MRGKALAGLLGLLVVLVASAEEMGLRDFNATQFSGLWYEIALASNLEPQTPPQLKKMGAVLVEREGPYLTLTSVSDHINRCVKETTQAVKGDAPGKFKFPKEPGNKDVTVVATDYRTYAIVNVAFQKGRTAHSVLKLYSEPLGALPSPRPAWPCGGHPQPGEGAGAASVALASAQAPAAKGTPPGQAGTWNTTRKSWPTSSWRPRSAGCPRPACSCSSRTVSVRAAGSGRPSPSPQVTILSCPQ", "length": 244, "header": "tr|A0A5G2R8K5-1|A0A5G2R8K5_PIG Isoform 1 of Lipocalin/cytosolic fatty-acid binding domain-containing protein OS=Sus scrofa OX=9823 GN=LCN5 PE=1 SV=1 CANONICAL=A0A5G2R8K5-1" }, "locus": { "chromosome": "AEMK02000682.1", "start_pos": 1040643, "end_pos": 1038720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083809.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083809.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070458.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070458.1" } ] } }, { "isoform_ac": "F1RVZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K5/entry#F1RVZ8-1", "sequence": { "sequence": "MRGKALAGLLGLLVVLVASAEEMGLRDFNATQFSGLWYEIALASNLEPQTPPQLKKMGAVLVEREGPYLTLTSVSDHINRCVKETTQAVKGDAPGKFKFPKEPGNKDVTVVATDYRTYAIVNVAFQKGRTAHSVLKLYSRDMEHNEKVMAHFLLEASERGLSTASVQLLLKDRECPGRGVRPPEPVSPGHHSLLSAVTCVNLLR", "length": 204, "header": "tr|F1RVZ8-1|A0A5G2R8K5_PIG Computationally mapped isoform of Lipocalin/cytosolic fatty-acid binding domain-containing protein OS=Sus scrofa OX=9823 GN=LCN5 PE=1 SV=4 CANONICAL=A0A5G2R8K5-1" }, "locus": { "chromosome": "AEMK02000682.1", "start_pos": 1040666, "end_pos": 1038720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006413.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006413.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006244.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006244.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RVZ8", "url": "https://www.uniprot.org/uniprotkb/F1RVZ8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M858-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "LOC100295548", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGNLLAALLGLLVVLAAGKEDLGLQNFSLTQFSGMWYEIALASNLEHQSSSPRRKVGAVIVEQDGPHLSLTSVSDHMNLCMKEKNQAVKGDAPGKFKIPLESGGKEVIVVATDYKTYAIMNIILNRGGKPSSVLKLYSRTLEHNEKATEKFVEKAVEQGLSVSNVQLLTKDLTCVNLLS", "length": 180 }, "evidence": [ { "id": "A0A5G2R8K5", "url": "https://omabrowser.org/oma/group/A0A5G2R8K5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2AJB7-1", "protein_name": "Epididymal-specific lipocalin-5", "gene_name": "Lcn5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCSVARHMESIMLFTLLGLCVGLAAGTEAAVVKDFDVNKFLGFWYEIALASKMGAYGLAHKEEKMGAMVVELKENLLALTTTYYNEGHCVLEKVAATQVDGSAKYKVTRISGEKEVVVVATDYMTYTVIDITSLVAGAVHRAMKLYSRSLDNNGEALNNFQKIALKHGFSETDIHILKHDLTCVNALQSGQI", "length": 192 }, "evidence": [ { "id": "A0A5G2R8K5", "url": "https://omabrowser.org/oma/group/A0A5G2R8K5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small molecule binding", "id": "GO:0036094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036094", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8K5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 244, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8K5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8K5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8K5" }, { "id": "PF00061", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipocalin/cytosolic fatty-acid binding", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 139, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RFH3-1", "uniprot_ac": "A0A5G2RFH3", "uniprot_id": "A0A5G2RFH3_PIG", "mass": { "chemical_mass": 266649.0, "monoisotopic_mass": 266649.0 }, "refseq": {}, "gene_names": [ { "name": "SON", "type": "recommended", "evidence": [ { "id": "A0A5G2RFH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3" } ] } ], "protein_names": [ { "name": "SON DNA and RNA binding protein", "type": "synonym", "evidence": [ { "id": "A0A5G2RFH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SON", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3", "locus": { "chromosome": "13", "start_pos": 197194078, "end_pos": 197162116, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000023674", "url": "https://www.ensembl.org/id/ENSSSCG00000023674" } ] } } ], "crossref": [ { "id": "ENSSSCG00000023674", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000023674", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19870", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19870", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396703", "url": "https://www.ncbi.nlm.nih.gov/gene/396703", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A287BK71", "url": "https://www.orthodb.org/?gene=A0A287BK71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46528", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46528", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46528:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46528:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14709", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14709", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AG18", "url": "https://www.uniprot.org/uniprotkb/A0A287AG18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AG18-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AG18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BK71", "url": "https://www.uniprot.org/uniprotkb/A0A287BK71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BK71-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BK71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R430", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R430", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R430-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R430-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L9C9", "url": "https://www.uniprot.org/uniprotkb/I3L9C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L9C9-1", "url": "https://www.uniprot.org/uniprotkb/I3L9C9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATNIEQIFRSFVVSKFREIQQELSSGRSEGQLNGETNTPIEGNQAGDAAASARTLPNEEIVQKIEEVLSGVLDTELRYKPDLKEASRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKKQPEESESKMKSHHDGNIDLESDSFLKFDSEPSAMALEHPLRVFGNSESPAVVLESPIVSMEVSEPHTLETLKPATKTAELSVASTSVVSVQSEQSVEVMLEPSTTKILDSFATAPVSTTTVVLKSSEPVVTMSVEYQMKSVLNTPPEPSKMLLEPPVAKVLEPSETLVSSETPTEVHPEPSTSTTVDFPESSATEVLRLPEQPVEVPSENADSSMTRPQEMLELPKTTALELQESSVASATELPGPPATSMPELQGPPVTPVLELPGPSATPVSELPGPLSTPVPELLGPPATAVPELPGPSVTSVPQLSQELPGLPAPSVGLEPPQEVPEPPVMAQELPGLPAVTAAVELPGQPVVTVAMELTEQPVTTTELEHPVGMTTVEHPGQPEVTTATGLLGQPEAAMVLEFPGQPVATTALELPGQPSVTGVPELPGLPSATRALELSGQPVATGALELPGQLMATGALEFSGQSGAAGALELLGQPLATGVLELPGQPGAPELPGQPVATVALEISVQSVVTTTELSTMTVSQSLEVPSTTALESYNTVAQELPTTLVGETSVTVGVDPLMAQESHMLASNTMETHMLASNTMDSQMLASNTMDSQMLASNTMDSQMLASSTMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSTMDSQMLATSSMDSQMLATSSMDSQMLASGTMDSQMLASGTMDAQMLASGTMDAQMLASSTQDSAMLGSKSPDPYRLAQDPYRLAQDPYRLGHDPYRLGHDAYRLGQDPYRLGHDPYRLTPDPYRMSPRPYRIAPRSYRIAPRPYRLAPRPLMLASRRSMMMSYAAERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTADRSMMSMAADSYTDSYTDTYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGSALPTEQSALAAENTWPIEVPALPPEESVSLPEPPVSQSEVSEPSAVPANYSVSASEPSALASEAAVTVPEPPLEPESSVTSTPVESAAVVEHEIVPERPVTYMVSETPMMSAEPTMLTSESETAETFDSMRASGHADSEISVSLLEPAVPIPEPSQSTLGLPAMAVSELPAVAVPEQSAGTVAEPPAMAVTEPLAVAAPDPPAVAVQDPPAEAVPEPLALSEPEHVTIPVPVVSALEPTVPILEPAVSVLQPNLIVSEPSISVQDPTVTISEPPVTVSEQTQVIPTEMVLESTPVILESSATKGMNLLSGDQNLAPEMGMQEIPMHSEEEPHAEGHLKNDCYETENGMSTDLNINNHLIAKEMEHNTVSAASIGAVGEMGEEKILPTHETKQCTVLDTCSSVSETDVGGTLSSTGPLALEPDAVGAGKGIEFATASALSSISKYDVEGALTTQDTEHDMVISTSPSGGSEADIEGPLLAKDIHLDLSSNSNFISKDAEESLPIQESDQTLAVALSPKETSGEDKEVPLPATEAVSDTGFPANIDDINEADLVRPLLPKDMERLTSLRAGIEGPLLSSEVERDKSAASPVVISIPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTGRARSRTPSRRSRSHTPSRRRRSRSGGRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLNKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKPIFFNLNFRLNTMRNNIIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDDDNVFSSSLPSEPVDISTAMSERALAQKRLSENAFDLEAMSMLNRAQERIDAWAQLNSIPGQFTGSTGVQVLTQEQLANTGAQAWIKKDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGLVAVGERAQKRSGNFSAAMKDLSGKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLINGSAYQPSFASPNKKHAKATAATVVLQAMGLVPKDLMANATCFRSASRR", "length": 2457, "header": "tr|A0A5G2RFH3-1|A0A5G2RFH3_PIG Isoform 1 of SON DNA and RNA binding protein OS=Sus scrofa OX=9823 GN=SON PE=1 SV=2 CANONICAL=A0A5G2RFH3-1" }, "isoforms": [ { "isoform_ac": "A0A287AG18-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3/entry#A0A287AG18-1", "sequence": { "sequence": "MATNIEQIFRSFVVSKFREIQQELSSGRSEGQLNGETNTPIEGNQAGDAAASARTLPNEEIVQKIEEVLSGVLDTELRYKPDLKEASRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKKQPEESESKMKSHHDGNIDLESDSFLKFDSEPSAMALEHPLRVFGNSESPAVVLESPIVSMEVSEPHTLETLKPATKTAELSVASTSVVSVQSEQSVEVMLEPSTTKILDSFATAPVSTTTVVLKSSEPVVTMSVEYQMKSVLNTPPEPSKMLLEPPVAKVLEPSETLVSSETPTEVHPEPSTSTTVDFPESSATEVLRLPEQPVEVPSENADSSMTRPQEMLELPKTTALELQESSVASATELPGPPATSMPELQGPPVTPVLELPGPSATPVSELPGPLSTPVPELLGPPATAVPELPGPSVTSVPQLSQELPGLPAPSVGLEPPQEVPEPPVMAQELPGLPAVTAAVELPGQPVVTVAMELTEQPVTTTELEHPVGMTTVEHPGQPEVTTATGLLGQPEAAMVLEFPGQPVATTALELPGQPSVTGVPELPGLPSATRALELSGQPVATGALELPGQLMATGALEFSGQSGAAGALELLGQPLATGVLELPGQPGAPELPGQPVATVALEISVQSVVTTTELSTMTVSQSLEVPSTTALESYNTVAQELPTTLVGETSVTVGVDPLMAQESHMLASNTMETHMLASNTMDSQMLASNTMDSQMLASNTMDSQMLASSTMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSTMDSQMLATSSMDSQMLATSSMDSQMLASGTMDSQMLASGTMDAQMLASGTMDAQMLASSTQDSAMLGSKSPDPYRLAQDPYRLAQDPYRLGHDPYRLGHDAYRLGQDPYRLGHDPYRLTPDPYRMSPRPYRIAPRSYRIAPRPYRLAPRPLMLASRRSMMMSYAAERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTADRSMMSMAADSYTDSYTDTYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGSALPTEQSALAAENTWPIEVPALPPEESVSLPEPPVSQSEVSEPSAVPANYSVSASEPSALASEAAVTVPEPPLEPESSVTSTPVESAAVVEHEIVPERPVTYMVSETPMMSAEPTMLTSESETAETFDSMRASGHADSEISVSLLEPAVPIPEPSQSTLGLPAMAVSELPAVAVPEQSAVAVTEPLAVAAPDPPAVAVQDPPAEAVPEPLALSEPEHVTIPVPVVSALEPTVPILEPAVSVLQPNLIVSEPSISVQDPTVTISEPPVTVSEQTQVIPTEMVLESTPVILESSATKGMNLLSGDQNLAPEMGMQEIPMHSEEEPHAEGHLKNDCYETENGMSTDLNINNHLIAKEMEHNTVSAASIGAVGEMGEEKILPTHETKQCTVLDTCSSVSETDVGGTLSSTGPLALEPDAVGAGKGIEFATASALSSISKYDVEGALTTQDTEHDMVISTSPSGGSEADIEGPLLAKDIHLDLSSNSNFISKDAEESLPIQESDQTLAVALSPKETSGEDKEVPLPATEAVSDTGFPANIDDINEADLVRPLLPKDMERLTSLRAGIEGPLLSSEVERDKSAASPVVISIPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTGRARSRTPSRRSRSHTPSRRRRSRSGGRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLNKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEF", "length": 2088, "header": "tr|A0A287AG18-1|A0A5G2RFH3_PIG Computationally mapped isoform of SON DNA and RNA binding protein OS=Sus scrofa OX=9823 GN=SON PE=1 SV=2 CANONICAL=A0A5G2RFH3-1" }, "locus": { "chromosome": "13", "start_pos": 197175016, "end_pos": 197162156, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063351.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063351.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042846.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042846.2" } ] } }, { "isoform_ac": "A0A287BK71-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3/entry#A0A287BK71-1", "sequence": { "sequence": "MATNIEQIFRSFVVSKFREIQQELSSGRSEGQLNGETNTPIEGNQAGDAAASARTLPNEEIVQKIEEVLSGVLDTELRYKPDLKEASRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKKQPEESESKMKSHHDGNIDLESDSFLKFDSEPSAMALEHPLRVFGNSESPAVVLESPIVSMEVSEPHTLETLKPATKTAELSVASTSVVSVQSEQSVEVMLEPSTTKILDSFATAPVSTTTVVLKSSEPVVTMSVEYQMKSVLNTPPEPSKMLLEPPVAKVLEPSETLVSSETPTEVHPEPSTSTTVDFPESSATEVLRLPEQPVEVPSENADSSMTRPQEMLELPKTTALELQESSVASATELPGPPATSMPELQGPPVTPVLELPGPSATPVSELPGPLSTPVPELLGPPATAVPELPGPSVTSVPQLSQELPGLPAPSVGLEPPQEVPEPPVMAQELPGLPAVTAAVELPGQPVVTVAMELTEQPVTTTELEHPVGMTTVEHPGQPEVTTATGLLGQPEAAMVLEFPGQPVATTALELPGQPSVTGVPELPGLPSATRALELSGQPVATGALELPGQLMATGALEFSGQSGAAGALELLGQPLATGVLELPGQPGAPELPGQPVATVALEISVQSVVTTTELSTMTVSQSLEVPSTTALESYNTVAQELPTTLVGETSVTVGVDPLMAQESHMLASNTMETHMLASNTMDSQMLASNTMDSQMLASNTMDSQMLASSTMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSTMDSQMLATSSMDSQMLATSSMDSQMLASGTMDSQMLASGTMDAQMLASGTMDAQMLASSTQDSAMLGSKSPDPYRLAQDPYRLAQDPYRLGHDPYRLGHDAYRLGQDPYRLGHDPYRLTPDPYRMSPRPYRIAPRSYRIAPRPYRLAPRPLMLASRRSMMMSYAAERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTADRSMMSMAADSYTDSYTDTYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGSALPTEQSALAAENTWPIEVPALPPEESVSLPEPPVSQSEVSEPSAVPANYSVSASEPSALASEAAVTVPEPPLEPESSVTSTPVESAAVVEHEIVPERPVTYMVSETPMMSAEPTMLTSESETAETFDSMRASGHADSEISVSLLEPAVPIPEPSQSTLGLPAMAVSELPAVAVPEQSAGTVAEPPAMAVTEPLAVAAPDPPAVAVQDPPAEAVPEPLALSEPEHVTIPVPVVSALEPTVPILEPAVSVLQPNLIVSEPSISVQDPTVTISEPPVTVSEQTQVIPTEMVLESTPVILESSATKGMNLLSGDQNLAPEMGMQEIPMHSEEEPHAEGHLKNDCYETENGMSTDLNINNHLIAKEMEHNTVSAASIGAVGEMGEEKILPTHETKQCTVLDTCSSVSETDVGGTLSSTGPLALEPDAVGAGKGIEFATASALSSISKYDVEGALTTQDTEHDMVISTSPSGGSEADIEGPLLAKDIHLDLSSNSNFISKDAEESLPIQESDQTLAVALSPKETSGEDKEVPLPATEAVSDTGFPANIDDINEADLVRPLLPKDMERLTSLRAGIEGPLLSSEVERDKSAASPVVISIPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTGRARSRTPSRRSRSHTPSRRRRSRSGGRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLNKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKPIFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDDDNVFSSSLPSEPVDISTAMSERALAQKRLSENAFDLEAMSMLNRAQERIDAWAQLNSIPGQFTGSTGVQVLTQEQLANTGAQAWIKKDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGLVAVGERAQKRSGNFSAAMKDLSGKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLINGSAYQPSFASPNKKHAKATAATVVLQAMGLVPKDLMANATCFRSASRR", "length": 2447, "header": "tr|A0A287BK71-1|A0A287BK71_PIG Computationally mapped isoform of SON DNA and RNA binding protein OS=Sus scrofa OX=9823 GN=SON PE=1 SV=2 CANONICAL=A0A5G2RFH3-1" }, "locus": { "chromosome": "13", "start_pos": 197192454, "end_pos": 197162156, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065483.2", "url": "https://www.ensembl.org/id/ENSSSCT00000065483.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056796.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056796.2" } ] } }, { "isoform_ac": "A0A5G2R430-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3/entry#A0A5G2R430-1", "sequence": { "sequence": "MATNIEQIFRSFVVSKFREIQQELSSGRSEGQLNGETNTPIEGNQAGDAAASARTLPNEEIVQKIEEVLSGVLDTELRYKPDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKPIFFNLNFRLNTMRNNIIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDDDNVFSSSLPSEPVDISTAMSERALAQKRLSENAFDLEAMSMLNRAQERIDAWAQLNSIPGQFTGSTGVQVLTQEQLANTGAQAWIKKDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGLVAVGERAQKRSGNFSAAMKDLSGKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRPNCMFFLNRY", "length": 455, "header": "tr|A0A5G2R430-1|A0A5G2RFH3_PIG Computationally mapped isoform of SON DNA and RNA binding protein OS=Sus scrofa OX=9823 GN=SON PE=1 SV=2 CANONICAL=A0A5G2RFH3-1" }, "locus": { "chromosome": "13", "start_pos": 197192302, "end_pos": 197162156, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075153.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075153.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068949.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068949.2" } ] } }, { "isoform_ac": "A0A5G2RFH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3/entry#A0A5G2RFH3-1", "sequence": { "sequence": "MATNIEQIFRSFVVSKFREIQQELSSGRSEGQLNGETNTPIEGNQAGDAAASARTLPNEEIVQKIEEVLSGVLDTELRYKPDLKEASRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKKQPEESESKMKSHHDGNIDLESDSFLKFDSEPSAMALEHPLRVFGNSESPAVVLESPIVSMEVSEPHTLETLKPATKTAELSVASTSVVSVQSEQSVEVMLEPSTTKILDSFATAPVSTTTVVLKSSEPVVTMSVEYQMKSVLNTPPEPSKMLLEPPVAKVLEPSETLVSSETPTEVHPEPSTSTTVDFPESSATEVLRLPEQPVEVPSENADSSMTRPQEMLELPKTTALELQESSVASATELPGPPATSMPELQGPPVTPVLELPGPSATPVSELPGPLSTPVPELLGPPATAVPELPGPSVTSVPQLSQELPGLPAPSVGLEPPQEVPEPPVMAQELPGLPAVTAAVELPGQPVVTVAMELTEQPVTTTELEHPVGMTTVEHPGQPEVTTATGLLGQPEAAMVLEFPGQPVATTALELPGQPSVTGVPELPGLPSATRALELSGQPVATGALELPGQLMATGALEFSGQSGAAGALELLGQPLATGVLELPGQPGAPELPGQPVATVALEISVQSVVTTTELSTMTVSQSLEVPSTTALESYNTVAQELPTTLVGETSVTVGVDPLMAQESHMLASNTMETHMLASNTMDSQMLASNTMDSQMLASNTMDSQMLASSTMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSTMDSQMLATSSMDSQMLATSSMDSQMLASGTMDSQMLASGTMDAQMLASGTMDAQMLASSTQDSAMLGSKSPDPYRLAQDPYRLAQDPYRLGHDPYRLGHDAYRLGQDPYRLGHDPYRLTPDPYRMSPRPYRIAPRSYRIAPRPYRLAPRPLMLASRRSMMMSYAAERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTADRSMMSMAADSYTDSYTDTYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGSALPTEQSALAAENTWPIEVPALPPEESVSLPEPPVSQSEVSEPSAVPANYSVSASEPSALASEAAVTVPEPPLEPESSVTSTPVESAAVVEHEIVPERPVTYMVSETPMMSAEPTMLTSESETAETFDSMRASGHADSEISVSLLEPAVPIPEPSQSTLGLPAMAVSELPAVAVPEQSAGTVAEPPAMAVTEPLAVAAPDPPAVAVQDPPAEAVPEPLALSEPEHVTIPVPVVSALEPTVPILEPAVSVLQPNLIVSEPSISVQDPTVTISEPPVTVSEQTQVIPTEMVLESTPVILESSATKGMNLLSGDQNLAPEMGMQEIPMHSEEEPHAEGHLKNDCYETENGMSTDLNINNHLIAKEMEHNTVSAASIGAVGEMGEEKILPTHETKQCTVLDTCSSVSETDVGGTLSSTGPLALEPDAVGAGKGIEFATASALSSISKYDVEGALTTQDTEHDMVISTSPSGGSEADIEGPLLAKDIHLDLSSNSNFISKDAEESLPIQESDQTLAVALSPKETSGEDKEVPLPATEAVSDTGFPANIDDINEADLVRPLLPKDMERLTSLRAGIEGPLLSSEVERDKSAASPVVISIPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTGRARSRTPSRRSRSHTPSRRRRSRSGGRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLNKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKPIFFNLNFRLNTMRNNIIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDDDNVFSSSLPSEPVDISTAMSERALAQKRLSENAFDLEAMSMLNRAQERIDAWAQLNSIPGQFTGSTGVQVLTQEQLANTGAQAWIKKDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGLVAVGERAQKRSGNFSAAMKDLSGKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLINGSAYQPSFASPNKKHAKATAATVVLQAMGLVPKDLMANATCFRSASRR", "length": 2457, "header": "tr|A0A5G2RFH3-1|A0A5G2RFH3_PIG Isoform 1 of SON DNA and RNA binding protein OS=Sus scrofa OX=9823 GN=SON PE=1 SV=2 CANONICAL=A0A5G2RFH3-1" }, "locus": { "chromosome": "13", "start_pos": 197192454, "end_pos": 197162156, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068477.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068477.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073557.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073557.2" } ] } }, { "isoform_ac": "I3L9C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3/entry#I3L9C9-1", "sequence": { "sequence": "MATNIEQIFRSFVVSKFREIQQELSSGRSEGQLNGETNTPIEGNQAGDAAASARTLPNEEIVQKIEEVLSGVLDTELRYKPDLKEASRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKKQPEESESKMKSHHDGNIDLESDSFLKFDSEPSAMALEHPLRVFGNSESPAVVLESPIVSMEVSEPHTLETLKPATKTAELSVASTSVVSVQSEQSVEVMLEPSTTKILDSFATAPVSTTTVVLKSSEPVVTMSVEYQMKSVLNTPPEPSKMLLEPPVAKVLEPSETLVSSETPTEVHPEPSTSTTVDFPESSATEVLRLPEQPVEVPSENADSSMTRPQEMLELPKTTALELQESSVASATELPGPPATSMPELQGPPVTPVLELPGPSATPVSELPGPLSTPVPELLGPPATAVPELPGPSVTSVPQLSQELPGLPAPSVGLEPPQEVPEPPVMAQELPGLPAVTAAVELPGQPVVTVAMELTEQPVTTTELEHPVGMTTVEHPGQPEVTTATGLLGQPEAAMVLEFPGQPVATTALELPGQPSVTGVPELPGLPSATRALELSGQPVATGALELPGQLMATGALEFSGQSGAAGALELLGQPLATGVLELPGQPGAPELPGQPVATVALEISVQSVVTTTELSTMTVSQSLEVPSTTALESYNTVAQELPTTLVGETSVTVGVDPLMAQESHMLASNTMETHMLASNTMDSQMLASNTMDSQMLASNTMDSQMLASSTMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSTMDSQMLATSSMDSQMLATSSMDSQMLASGTMDSQMLASGTMDAQMLASGTMDAQMLASSTQDSAMLGSKSPDPYRLAQDPYRLAQDPYRLGHDPYRLGHDAYRLGQDPYRLGHDPYRLTPDPYRMSPRPYRIAPRSYRIAPRPYRLAPRPLMLASRRSMMMSYAAERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTADRSMMSMAADSYTDSYTDTYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGSALPTEQSALAAENTWPIEVPALPPEESVSLPEPPVSQSEVSEPSAVPANYSVSASEPSALASEAAVTVPEPPLEPESSVTSTPVESAAVVEHEIVPERPVTYMVSETPMMSAEPTMLTSESETAETFDSMRASGHADSEISVSLLEPAVPIPEPSQSTLGLPAMAVSELPAVAVPEQSAGTVAEPPAMAVTEPLAVAAPDPPAVAVQDPPAEAVPEPLALSEPEHVTIPVPVVSALEPTVPILEPAVSVLQPNLIVSEPSISVQDPTVTISEPPVTVSEQTQVIPTEMVLESTPVILESSATKGMNLLSGDQNLAPEMGMQEIPMHSEEEPHAEGHLKNDCYETENGMSTDLNINNHLIAKEMEHNTVSAASIGAVGEMGEEKILPTHETKQCTVLDTCSSVSETDVGGTLSSTGPLALEPDAVGAGKGIEFATASALSSISKYDVEGALTTQDTEHDMVISTSPSGGSEADIEGPLLAKDIHLDLSSNSNFISKDAEESLPIQESDQTLAVALSPKETSGEDKEVPLPATEAVSDTGFPANIDDINEADLVRPLLPKDMERLTSLRAGIEGPLLSSEVERDKSAASPVVISIPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTGRARSRTPSRRSRSHTPSRRRRSRSGGRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLNKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKPIFFNLNFRLNTMRNNIIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDDDNVFSSSLPSEGRVKRQGRVRRQMKQPAASHLTVTRCNSLCGTKPQSEKHRIAENSVITSLPNIGPSLHLWEGSPRYNYLASRFASRLYSSRFWW", "length": 2301, "header": "tr|I3L9C9-1|A0A5G2RFH3_PIG Computationally mapped isoform of SON DNA and RNA binding protein OS=Sus scrofa OX=9823 GN=SON PE=1 SV=4 CANONICAL=A0A5G2RFH3-1" }, "locus": { "chromosome": "13", "start_pos": 197177592, "end_pos": 197162156, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026483.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026483.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020641.4", "url": "https://www.ensembl.org/id/ENSSSCP00000020641.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1159, "start_aa": "Thr", "end_pos": 1159, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1159", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2161, "start_aa": "Thr", "end_pos": 2161, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2161", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 402, "start_aa": "Thr", "end_pos": 402, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr402", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R430", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R430" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1220, "end_pos": 1222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2357, "end_pos": 2359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2409, "end_pos": 2411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2447, "end_pos": 2449, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RFH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3" }, { "id": "PS50137", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50137" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DRBM", "eco_id": "ECO_0000259", "start_pos": 2369, "end_pos": 2439, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RFH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFH3" }, { "id": "PS50174", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-patch", "eco_id": "ECO_0000259", "start_pos": 2303, "end_pos": 2349, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 402, 1159, 2161 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1220, "end_pos": 1222 }, { "start_pos": 2357, "end_pos": 2359 }, { "start_pos": 2409, "end_pos": 2411 }, { "start_pos": 2447, "end_pos": 2449 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9K5-1", "uniprot_ac": "A0A5G2R9K5", "uniprot_id": "A0A5G2R9K5_PIG", "mass": { "chemical_mass": 401642.0, "monoisotopic_mass": 401642.0 }, "refseq": {}, "gene_names": [ { "name": "CSMD3", "type": "recommended", "evidence": [ { "id": "A0A5G2R9K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5" } ] } ], "protein_names": [ { "name": "CUB and sushi domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A5G2R9K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5/entry#names_and_taxonomy" } ] }, { "name": "CUB and sushi multiple domains protein 3", "type": "synonym", "evidence": [ { "id": "A0A5G2R9K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in dendrite development.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5#function" }, { "database": "UniProtKB", "id": "ARBA00055925", "url": "https://www.uniprot.org/uniprotkb/ARBA00055925#function" }, { "database": "UniProtKB", "id": "A0A5G2QUF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUF6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CSMD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5", "locus": { "chromosome": "4", "start_pos": 25870856, "end_pos": 24648200, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031031", "url": "https://www.ensembl.org/id/ENSSSCG00000031031" } ] } } ], "crossref": [ { "id": "ENSSSCG00000031031", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031031", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24255", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24255", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24255:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24255:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287ALI0", "url": "https://www.uniprot.org/uniprotkb/A0A287ALI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ALI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ALI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGIRKGESRVKESKPREPGKRKCAKCGRLDFLLMKKMGIKSGFTFWNLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEHNRTTTGAIAVASTSADVTVSSVTAVTIHRLSEEQRVQVKNLRNSGLDPNTSKDGLAPHQADTQSTRRRPRNAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRVGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPDSPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGPIPRCGAPCGGHFSAPSGLILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDPGYRLSHEEPLLCEKNHWWSHPLPTCDGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSELPSTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCKDPGIPQFGNRIGFSFGVGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDSEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWVIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENEMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSLVLFECNPGYILHGSIAIRCDTVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIQLPVGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNISMFVEFFQTEKEFDVLQVYDGPNIQSPVLVSLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFTLEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDSGFMLVGSAVRECLSSGLWSGSETRCLAGHCGVPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNTGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRTLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESDFRTKSSVRFACDTGYILHGSEERTCLANGSWTGRQPECKAIQCGNPGTTANGKVFRIDGTTFSSSVIYSCIEGYILSGPSVRQCTANGTWSGTLPNCTIISCEDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTTNGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNSPFILVGSSTRICQADGTWSGSSPHCIEPTRTSCDNPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECTPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLHIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "length": 3668, "header": "tr|A0A5G2R9K5-1|A0A5G2R9K5_PIG Isoform 1 of CUB and sushi domain-containing protein 3 OS=Sus scrofa OX=9823 GN=CSMD3 PE=3 SV=2 CANONICAL=A0A5G2R9K5-1" }, "isoforms": [ { "isoform_ac": "A0A287ALI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5/entry#A0A287ALI0-1", "sequence": { "sequence": "MKGIRKGESRVKESKPREPGKRKCAKCGRLDFLLMKKMGIKSGFTFWNLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVNEGGIKTASNLCPDPGEPENGKRVGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPDSPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGPIPRCGAPCGGHFSAPSGLILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERSLQILFYLKKYVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDPGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSELPSTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCKDPGIPQFGNRIGFSFGVGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDSEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWVIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENEMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSLVLFECNPGYILHGSIAIRCDTVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGK", "length": 1815, "header": "tr|A0A287ALI0-1|A0A5G2R9K5_PIG Computationally mapped isoform of CUB and sushi domain-containing protein 3 OS=Sus scrofa OX=9823 GN=CSMD3 PE=3 SV=2 CANONICAL=A0A5G2R9K5-1" }, "locus": { "chromosome": "4", "start_pos": 25703081, "end_pos": 24648285, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048043.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048043.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044753.2", "url": "https://www.ensembl.org/id/ENSSSCP00000044753.2" } ] } }, { "isoform_ac": "A0A5G2QUF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5/entry#A0A5G2QUF6-1", "sequence": { "sequence": "MKGIRKGESRVKESKPREPGKRKCAKCGRLDFLLMKKMGIKSGFTFWNLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRVGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPDSPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGPIPRCGAPCGGHFSAPSGLILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDPGYRLSHEEPLLCEKNHWWSHPLPTCDGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSELPSTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCKDPGIPQFGNRIGFSFGVGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDSEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWVIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENEMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSLVLFECNPGYILHGSIAIRCDTVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIQLPVGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNISMFVEFFQTEKEFDVLQVYDGPNIQSPVLVSLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDSGFMLVGSAVRECLSSGLWSGSETRCLAGHCGVPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNTGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRTLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESDFRTKSSVRFACDTGYILHGSEERTCLANGSWTGRQPECKAIQCGNPGTTANGKVFRIDGTTFSSSVIYSCIEGYILSGPSVRQCTANGTWSGTLPNCTIISCEDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTTNGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNSPFILVGSSTRICQADGTWSGSSPHCIEPTRTSCDNPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECTPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLHIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "length": 3499, "header": "tr|A0A5G2QUF6-1|A0A5G2R9K5_PIG Computationally mapped isoform of CUB and sushi domain-containing protein 3 OS=Sus scrofa OX=9823 GN=CSMD3 PE=3 SV=2 CANONICAL=A0A5G2R9K5-1" }, "locus": { "chromosome": "4", "start_pos": 25869000, "end_pos": 24648285, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084147.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084147.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061796.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061796.2" } ] } }, { "isoform_ac": "A0A5G2R9K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5/entry#A0A5G2R9K5-1", "sequence": { "sequence": "MKGIRKGESRVKESKPREPGKRKCAKCGRLDFLLMKKMGIKSGFTFWNLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEHNRTTTGAIAVASTSADVTVSSVTAVTIHRLSEEQRVQVKNLRNSGLDPNTSKDGLAPHQADTQSTRRRPRNAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRVGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPDSPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGPIPRCGAPCGGHFSAPSGLILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDPGYRLSHEEPLLCEKNHWWSHPLPTCDGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSELPSTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCKDPGIPQFGNRIGFSFGVGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDSEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWVIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENEMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSLVLFECNPGYILHGSIAIRCDTVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIQLPVGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNISMFVEFFQTEKEFDVLQVYDGPNIQSPVLVSLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFTLEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDSGFMLVGSAVRECLSSGLWSGSETRCLAGHCGVPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNTGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRTLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESDFRTKSSVRFACDTGYILHGSEERTCLANGSWTGRQPECKAIQCGNPGTTANGKVFRIDGTTFSSSVIYSCIEGYILSGPSVRQCTANGTWSGTLPNCTIISCEDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTTNGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNSPFILVGSSTRICQADGTWSGSSPHCIEPTRTSCDNPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECTPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLHIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "length": 3668, "header": "tr|A0A5G2R9K5-1|A0A5G2R9K5_PIG Isoform 1 of CUB and sushi domain-containing protein 3 OS=Sus scrofa OX=9823 GN=CSMD3 PE=3 SV=2 CANONICAL=A0A5G2R9K5-1" }, "locus": { "chromosome": "4", "start_pos": 25869000, "end_pos": 24648285, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067515.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067515.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070809.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070809.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2725, "start_aa": "Thr", "end_pos": 2725, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2725", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3022, "start_aa": "Thr", "end_pos": 3022, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3022", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3196, "start_aa": "Thr", "end_pos": 3196, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3196", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3444, "start_aa": "Thr", "end_pos": 3444, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3444", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUF6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of dendrite development", "id": "GO:0050773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050773", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9K5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1087, "end_pos": 1089, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1132, "end_pos": 1134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1241, "end_pos": 1243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1497, "end_pos": 1499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1552, "end_pos": 1554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1670, "end_pos": 1672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1742, "end_pos": 1744, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1890, "end_pos": 1892, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1980, "end_pos": 1982, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2116, "end_pos": 2118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2247, "end_pos": 2249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2252, "end_pos": 2254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2285, "end_pos": 2287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2456, "end_pos": 2458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2498, "end_pos": 2500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2645, "end_pos": 2647, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2672, "end_pos": 2674, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2703, "end_pos": 2705, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2823, "end_pos": 2825, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2893, "end_pos": 2895, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2913, "end_pos": 2915, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3060, "end_pos": 3062, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3119, "end_pos": 3121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3128, "end_pos": 3130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3155, "end_pos": 3157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3169, "end_pos": 3171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3179, "end_pos": 3181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3237, "end_pos": 3239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3325, "end_pos": 3327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3483, "end_pos": 3485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3490, "end_pos": 3492, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3573, "end_pos": 3575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3579, "end_pos": 3581, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3588, "end_pos": 3590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 724, "end_pos": 726, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 823, "end_pos": 825, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" }, { "start_pos": 966, "end_pos": 968, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 173, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R9K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9K5" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 176, "end_pos": 237, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 2725, 3022, 3196, 3444 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1087, "end_pos": 1089 }, { "start_pos": 1132, "end_pos": 1134 }, { "start_pos": 1241, "end_pos": 1243 }, { "start_pos": 1497, "end_pos": 1499 }, { "start_pos": 1552, "end_pos": 1554 }, { "start_pos": 1670, "end_pos": 1672 }, { "start_pos": 1742, "end_pos": 1744 }, { "start_pos": 1890, "end_pos": 1892 }, { "start_pos": 1980, "end_pos": 1982 }, { "start_pos": 2116, "end_pos": 2118 }, { "start_pos": 2247, "end_pos": 2249 }, { "start_pos": 2252, "end_pos": 2254 }, { "start_pos": 2285, "end_pos": 2287 }, { "start_pos": 2456, "end_pos": 2458 }, { "start_pos": 2498, "end_pos": 2500 }, { "start_pos": 2645, "end_pos": 2647 }, { "start_pos": 2672, "end_pos": 2674 }, { "start_pos": 2703, "end_pos": 2705 }, { "start_pos": 2823, "end_pos": 2825 }, { "start_pos": 2893, "end_pos": 2895 }, { "start_pos": 2913, "end_pos": 2915 }, { "start_pos": 3060, "end_pos": 3062 }, { "start_pos": 3119, "end_pos": 3121 }, { "start_pos": 3128, "end_pos": 3130 }, { "start_pos": 3155, "end_pos": 3157 }, { "start_pos": 3169, "end_pos": 3171 }, { "start_pos": 3179, "end_pos": 3181 }, { "start_pos": 3237, "end_pos": 3239 }, { "start_pos": 3325, "end_pos": 3327 }, { "start_pos": 3483, "end_pos": 3485 }, { "start_pos": 3490, "end_pos": 3492 }, { "start_pos": 3573, "end_pos": 3575 }, { "start_pos": 3579, "end_pos": 3581 }, { "start_pos": 3588, "end_pos": 3590 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 409, "end_pos": 411 }, { "start_pos": 724, "end_pos": 726 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 823, "end_pos": 825 }, { "start_pos": 90, "end_pos": 92 }, { "start_pos": 966, "end_pos": 968 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7E3-1", "uniprot_ac": "A0A5G2R7E3", "uniprot_id": "A0A5G2R7E3_PIG", "mass": { "chemical_mass": 40997.0, "monoisotopic_mass": 40997.0 }, "refseq": {}, "gene_names": [ { "name": "FAM3D", "type": "recommended", "evidence": [ { "id": "A0A5G2R7E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ] } ], "protein_names": [ { "name": "Actin-associated protein FAM107A", "type": "recommended", "evidence": [ { "id": "A0A5G2R7E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory. Plays a role in the actin and microtubule cytoskeleton organization; negatively regulates focal adhesion (FA) assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner. Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner. May play a role in tumor development.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3#function" }, { "database": "UniProtKB", "id": "ARBA00045129", "url": "https://www.uniprot.org/uniprotkb/ARBA00045129#function" }, { "database": "UniProtKB", "id": "A0A287BB34", "url": "https://www.uniprot.org/uniprotkb/A0A287BB34#function" }, { "database": "UniProtKB", "id": "A0A287AWW8", "url": "https://www.uniprot.org/uniprotkb/A0A287AWW8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FAM3D", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3", "locus": {} } ], "crossref": [ { "id": "A0A5G2R7E3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7E3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000033189", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033189", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13940", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13940", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR009533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A287AWW8", "url": "https://www.orthodb.org/?gene=A0A287AWW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16768", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16768", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16768:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16768:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AWW8", "url": "https://www.uniprot.org/uniprotkb/A0A287AWW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AWW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AWW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BB34", "url": "https://www.uniprot.org/uniprotkb/A0A287BB34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BB34-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BB34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVSGLPRLLALIFVLVTTWIFVRSYISFNMKTIRLPRWMAGSVHKEKLVKIKCGLSKSCPANFFAFKIVSGAANVVGPSMCLEDHVIMSPVKNNVGRGLNIALVNGTTGTILGQKSFDMYSGDPSLLVKFLKEIPAGTLVLVASYDDPGTKLNDEIRQLFSNLGSAYTKQLGFRDSWVFLGAKDLKGKSPFEQFLKNNPDTNKYEAPPLIPAASMYSEIQRERADIGGLMARPEYREWNPELIKPKKLLNPVKASRSHQELHRELLMNHKRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEKEEEHAPEFIKVRENLRRIATLTSEERVL", "length": 359, "header": "tr|A0A5G2R7E3-1|A0A5G2R7E3_PIG Isoform 1 of Actin-associated protein FAM107A OS=Sus scrofa OX=9823 GN=FAM3D PE=1 SV=2 CANONICAL=A0A5G2R7E3-1" }, "isoforms": [ { "isoform_ac": "A0A287AWW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3/entry#A0A287AWW8-1", "sequence": { "sequence": "MGAAQGKKKEYSPLAVFHNENEKQRLNGSASMYSEIQRERADIGGLMARPEYREWNPELIKPKKLLNPVKASRSHQELHRELLMNHKRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEKEEEHAPEFIKVRENLRRIATLTSEERVL", "length": 175, "header": "tr|A0A287AWW8-1|A0A5G2R7E3_PIG Computationally mapped isoform of Actin-associated protein FAM107A OS=Sus scrofa OX=9823 GN=FAM3D PE=1 SV=2 CANONICAL=A0A5G2R7E3-1" }, "locus": { "chromosome": "13", "start_pos": 40369431, "end_pos": 40279332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044053.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044053.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048363.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048363.2" } ] } }, { "isoform_ac": "A0A287BB34-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3/entry#A0A287BB34-1", "sequence": { "sequence": "MAQRLGERARGPAEATGLYRAVLLRSASMYSEIQRERADIGGLMARPEYREWNPELIKPKKLLNPVKASRSHQELHRELLMNHKRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEKEEEHAPEFIKVRENLRRIATLTSEERVL", "length": 172, "header": "tr|A0A287BB34-1|A0A287BB34_PIG Computationally mapped isoform of Actin-associated protein FAM107A OS=Sus scrofa OX=9823 GN=FAM3D PE=4 SV=1 CANONICAL=A0A5G2R7E3-1" }, "locus": { "chromosome": "13", "start_pos": 40307692, "end_pos": 40279332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048818.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048818.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053549.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053549.1" } ] } }, { "isoform_ac": "A0A5G2R7E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3/entry#A0A5G2R7E3-1", "sequence": { "sequence": "MRVSGLPRLLALIFVLVTTWIFVRSYISFNMKTIRLPRWMAGSVHKEKLVKIKCGLSKSCPANFFAFKIVSGAANVVGPSMCLEDHVIMSPVKNNVGRGLNIALVNGTTGTILGQKSFDMYSGDPSLLVKFLKEIPAGTLVLVASYDDPGTKLNDEIRQLFSNLGSAYTKQLGFRDSWVFLGAKDLKGKSPFEQFLKNNPDTNKYEAPPLIPAASMYSEIQRERADIGGLMARPEYREWNPELIKPKKLLNPVKASRSHQELHRELLMNHKRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEKEEEHAPEFIKVRENLRRIATLTSEERVL", "length": 359, "header": "tr|A0A5G2R7E3-1|A0A5G2R7E3_PIG Isoform 1 of Actin-associated protein FAM107A OS=Sus scrofa OX=9823 GN=FAM3D PE=1 SV=2 CANONICAL=A0A5G2R7E3-1" }, "locus": { "chromosome": "13", "start_pos": 40398359, "end_pos": 40279332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087305.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087305.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066521.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066521.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AWW8", "url": "https://www.uniprot.org/uniprotkb/A0A287AWW8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ], "pmid": "" }, { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7E3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7E3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 359, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7E3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7E3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E3" }, { "id": "PF15711", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15711" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ILEI/PANDER", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 185, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RFD8-1", "uniprot_ac": "A0A5G2RFD8", "uniprot_id": "A0A5G2RFD8_PIG", "mass": { "chemical_mass": 67329.0, "monoisotopic_mass": 67329.0 }, "refseq": {}, "gene_names": [ { "name": "TDRKH", "type": "recommended", "evidence": [ { "id": "A0A5G2RFD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ] } ], "protein_names": [ { "name": "Tudor and KH domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RFD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8/entry#names_and_taxonomy" } ] }, { "name": "Tudor domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "A0A5G2RFD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8#function" }, { "database": "UniProtKB", "id": "ARBA00057898", "url": "https://www.uniprot.org/uniprotkb/ARBA00057898#function" }, { "database": "UniProtKB", "id": "A0A287AXQ7", "url": "https://www.uniprot.org/uniprotkb/A0A287AXQ7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TDRKH", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8", "locus": { "chromosome": "4", "start_pos": 97438691, "end_pos": 97415914, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027770", "url": "https://www.ensembl.org/id/ENSSSCG00000027770" } ] } } ], "crossref": [ { "id": "A0A5G2RFD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000027770", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027770", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20412", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20412", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22428", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22428", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22429", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22429", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22948", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22948:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AXQ7", "url": "https://www.uniprot.org/uniprotkb/A0A287AXQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQESVKLIIGRQGANIKQLRKQTGARIDVDTEDIGDERVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREEVRAPGGAGEPALWKNTGPSLEQPAPLAVPPHKGGGDLAVIGPEESSWEKNNDDSFQMSGAQTSSEMSMFEIPSPDFSFHADEFLEVYVSASEHPNHFWIQIIGSRSLQLDKLISEMTQHYENSLPEDLTVHVGDIVAAPLPTNGSWYRAQVLGTLENGNLDLYFVDFGDNGDCPLRDLRVLRSDFLSLPFQAIECSLARIAPTGDQWEEEALDEFDRLTHCANWKPLVAKISSYVQSGVSTWPQIYLYDTSNGKKLDIGLELVRKGYAIELPEDMEENGAIPVMLHKVATETDVSLSSMLTETKKSPGEMANTLSCLSLSGSNSICSLEHLHITHSFFPSCLFRAALKAYGSSKSRGQIGAVAASLHHKQHRIRATSVTYTTAHSNT", "length": 611, "header": "tr|A0A5G2RFD8-1|A0A5G2RFD8_PIG Isoform 1 of Tudor and KH domain-containing protein OS=Sus scrofa OX=9823 GN=TDRKH PE=1 SV=1 CANONICAL=A0A5G2RFD8-1" }, "isoforms": [ { "isoform_ac": "A0A287AXQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8/entry#A0A287AXQ7-1", "sequence": { "sequence": "MICAEERLTFVGEDDIEIEMRVPQESVKLIIGRQGANIKQLRKQTGARIDVDTEDIGDERVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREEVRAPGGAGEPALWKNTGPSLEQPAPLAVPPHKGGGDLAVIGPEESSWEKNNDDSFQMSGAQTSSEMSMFEIPSPDFSFHADEFLEVYVSASEHPNHFWIQIIGSRSLQLDKLISEMTQHYENSLPEDLTVHVGDIVAAPLPTNGSWYRAQVLGTLENGNLDLYFVDFGDNGDCPLRDLRVLRSDFLSLPFQAIECSLARIAPTGDQWEEEALDEFDRLTHCANWKPLVAKISSYVQSGVSTWPQIYLYDTSNGKKLDIGLELVRKGYAIELPEDMEENGAIPVMLHKVATETDVSLSSMLTETKKSPGEMANTLSCLSLSEAASISGDDNLEDD", "length": 521, "header": "tr|A0A287AXQ7-1|A0A5G2RFD8_PIG Computationally mapped isoform of Tudor and KH domain-containing protein OS=Sus scrofa OX=9823 GN=TDRKH PE=1 SV=1 CANONICAL=A0A5G2RFD8-1" }, "locus": { "chromosome": "4", "start_pos": 97437327, "end_pos": 97429776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057560.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057560.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048918.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048918.2" } ] } }, { "isoform_ac": "A0A5G2RFD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8/entry#A0A5G2RFD8-1", "sequence": { "sequence": "MATERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQESVKLIIGRQGANIKQLRKQTGARIDVDTEDIGDERVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREEVRAPGGAGEPALWKNTGPSLEQPAPLAVPPHKGGGDLAVIGPEESSWEKNNDDSFQMSGAQTSSEMSMFEIPSPDFSFHADEFLEVYVSASEHPNHFWIQIIGSRSLQLDKLISEMTQHYENSLPEDLTVHVGDIVAAPLPTNGSWYRAQVLGTLENGNLDLYFVDFGDNGDCPLRDLRVLRSDFLSLPFQAIECSLARIAPTGDQWEEEALDEFDRLTHCANWKPLVAKISSYVQSGVSTWPQIYLYDTSNGKKLDIGLELVRKGYAIELPEDMEENGAIPVMLHKVATETDVSLSSMLTETKKSPGEMANTLSCLSLSGSNSICSLEHLHITHSFFPSCLFRAALKAYGSSKSRGQIGAVAASLHHKQHRIRATSVTYTTAHSNT", "length": 611, "header": "tr|A0A5G2RFD8-1|A0A5G2RFD8_PIG Isoform 1 of Tudor and KH domain-containing protein OS=Sus scrofa OX=9823 GN=TDRKH PE=1 SV=1 CANONICAL=A0A5G2RFD8-1" }, "locus": { "chromosome": "4", "start_pos": 97436851, "end_pos": 97428984, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080359.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080359.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073502.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073502.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AXQ7", "url": "https://www.uniprot.org/uniprotkb/A0A287AXQ7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ], "pmid": "" }, { "name": "P granule", "id": "GO:0043186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ], "pmid": "" }, { "name": "pi-body", "id": "GO:0071546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071546", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ], "pmid": "" }, { "name": "piP-body", "id": "GO:0071547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071547", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ], "pmid": "" }, { "name": "piRNA processing", "id": "GO:0034587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034587", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ], "pmid": "" }, { "name": "P granule organization", "id": "GO:0030719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030719", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ], "pmid": "" }, { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ], "pmid": "" }, { "name": "male meiotic nuclear division", "id": "GO:0007140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007140", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RFD8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 611, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RFD8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFD8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RFD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFD8" }, { "id": "PS50304", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50304" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tudor", "eco_id": "ECO_0000259", "start_pos": 353, "end_pos": 412, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 367, "end_pos": 369 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R840-1", "uniprot_ac": "A0A5G2R840", "uniprot_id": "A0A5G2R840_PIG", "mass": { "chemical_mass": 66023.0, "monoisotopic_mass": 66023.0 }, "refseq": {}, "gene_names": [ { "name": "HABP2", "type": "recommended", "evidence": [ { "id": "A0A5G2R840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840" } ] } ], "protein_names": [ { "name": "Factor VII-activating protease", "type": "recommended", "evidence": [ { "id": "A0A5G2R840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840/entry#names_and_taxonomy" } ] }, { "name": "Hepatocyte growth factor activator-like protein", "type": "synonym", "evidence": [ { "id": "A0A5G2R840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840/entry#names_and_taxonomy" } ] }, { "name": "Hyaluronan-binding protein 2", "type": "synonym", "evidence": [ { "id": "A0A5G2R840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840/entry#names_and_taxonomy" } ] }, { "name": "Plasma hyaluronan-binding protein", "type": "synonym", "evidence": [ { "id": "A0A5G2R840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII. May function as a tumor suppressor negatively regulating cell proliferation and cell migration.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R840", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840#function" }, { "database": "UniProtKB", "id": "ARBA00093410", "url": "https://www.uniprot.org/uniprotkb/ARBA00093410#function" }, { "database": "UniProtKB", "id": "A0A287AZ81", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ81#function" }, { "database": "UniProtKB", "id": "A0A5G2R378", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R378#function" }, { "database": "UniProtKB", "id": "A0A8W4F6U9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6U9#function" }, { "database": "UniProtKB", "id": "F1S5J5", "url": "https://www.uniprot.org/uniprotkb/F1S5J5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R840", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HABP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840", "locus": { "chromosome": "14", "start_pos": 123932961, "end_pos": 123893996, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010639", "url": "https://www.ensembl.org/id/ENSSSCG00000010639" } ] } } ], "crossref": [ { "id": "A0A5G2R840", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R840", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010639", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010639", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00108", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00108", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24264", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24264:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24264:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00051", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00051", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AZ81", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AZ81-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R378", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R378", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R378-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R378-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R840", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R840-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6U9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5J5", "url": "https://www.uniprot.org/uniprotkb/F1S5J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5J5-1", "url": "https://www.uniprot.org/uniprotkb/F1S5J5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFARKSELHVLLFMVLAAKTAFGFSLLSLLTDLDPGFWPCPMPMLACCGHTKPLKRKHDALLLAASSVSEAGKTHWTPENYEYSYENYNQEENSSAPAHHENPDWYYTEDDPCLSNPCAHGGDCLVSGDTFTCSCPAPYSGNRCQKVQNKCKNKPCGRGECLITQSPPYYRCACKHPYRGPDCSTVVPVCRPNPCQNGGTCSRHRRRSKFTCTCPDQFKGRFCEIGSDDCYVGDGYSYRGEVSKTVNQHTCLYWNSHLLLQENYNMFMEDAEAHGIGEHNFCRNPDGDRKPWCFIKVSSAKVKWEYCDVPACSAPEGSPIEPVTELPGFDSCGRTETAERKFKRIYGGFKSTAGKHPWQASLQTSLHLTVSMPQGHFCGGALIHPCWVLTAAHCTDIKAKYLKVVLGDQDLKKTELHEQSFGVEKIFKHSRYREKDDIPYNDIALLKLKPVDGHCALESKYVKTVCLPDSPFPSGTECYISGWGVTETGEGSRQLLDAKVKLISNAVCNSRRLYDHMLDDNMICAGNLQKPGQDSCQGDSGGPLTCEKDDAYYVYGIVSWGLECGKKPGVYTQVTTFLNWIRATMEREASF", "length": 591, "header": "tr|A0A5G2R840-1|A0A5G2R840_PIG Isoform 1 of Factor VII-activating protease OS=Sus scrofa OX=9823 GN=HABP2 PE=1 SV=1 CANONICAL=A0A5G2R840-1" }, "isoforms": [ { "isoform_ac": "A0A287AZ81-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840/entry#A0A287AZ81-1", "sequence": { "sequence": "MFARKSELHVLLFMVLAAKTAFGFSLLSLLTDLDPDWTPENYEYSYENYNQEENSSAPAHHENPDWYYTEDDPCLSNPCAHGGDCLVSGDTFTCSCPAPYSGNRCQKVQNKCKNKPCGRGECLITQSPPYYRCACKHPYRGPDCSTVVPVCRPNPCQNGGTCSRHRRRSKFTCTCPDQFKGRFCEIGSDDCYVGDGYSYRGEVSKTVNQHTCLYWNSHLLLQENYNMFMEDAEAHGIGEHNFCRNPDGDRKPWCFIKVSSAKVKWEYCDVPACSAPSPSEGSPIEPVTELPGFDSCGRTETAERKFKRIYGGFKSTAGKHPWQASLQTSLHLTVSMPQGHFCGGALIHPCWVLTAAHCTDIKAKYLKVVLGDQDLKKTELHEQSFGVEKIFKHSRYREKDDIPYNDIALLKLKPVDGHCALESKYVKTVCLPDSPFPSGTECYISGWGVTETGEGSRQLLDAKVKLISNAVCNSRRLYDHMLDDNMICAGNLQKPGQDSCQGDSGGPLTCEKDDAYYVYGIVSWGLECGKKPGVYTQVTTFLNWIRATMEREASF", "length": 555, "header": "tr|A0A287AZ81-1|A0A5G2R840_PIG Computationally mapped isoform of Factor VII-activating protease OS=Sus scrofa OX=9823 GN=HABP2 PE=1 SV=2 CANONICAL=A0A5G2R840-1" }, "locus": { "chromosome": "14", "start_pos": 123928255, "end_pos": 123894098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050318.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050318.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049451.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049451.2" } ] } }, { "isoform_ac": "A0A5G2R378-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840/entry#A0A5G2R378-1", "sequence": { "sequence": "MFARKSELHVLLFMVLAAKTAFGFSLLSLLTDLDPDWTPENYEYSYENYNQEENSSAPAHHENPDWYYTEDDPCLSNPCAHGGDCLVSGDTFTCSCPAPYSGNRCQKVQNKCKNKPCGRGECLITQSPPYYRCACKHPYRGPDCSTVVPVCRPNPCQNGGTCSRHRRRSKFTCTCPDQFKGRFCEIGSDDCYVGDGYSYRGEVSKTVNQHTCLYWNSHLLLQENYNMFMEDAEAHGIGEHNFCRNPDGDRKPWCFIKVSSAKVKWEYCDVPACSAPEGSPIEPVTELPGFDSCGRTETAERKFKRIYGGFKSTAGKHPWQASLQTSLHLTVSMPQGHFCGGALIHPCWVLTAAHCTDIKAKYLKVVLGDQDLKKTELHEQSFGVEKIFKHSRYREKDDIPYNDIALLKLKPVDGHCALESKYVKTVCLPDSPFPSGTECYISGWGVTETGEGSRQLLDAKVKLISNAVCNSRRLYDHMLDDNMICAGNLQKPGQDSCQAGSLGAQQIQACASR", "length": 513, "header": "tr|A0A5G2R378-1|A0A5G2R840_PIG Computationally mapped isoform of Factor VII-activating protease OS=Sus scrofa OX=9823 GN=HABP2 PE=1 SV=1 CANONICAL=A0A5G2R840-1" }, "locus": { "chromosome": "14", "start_pos": 123927640, "end_pos": 123894098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073928.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073928.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065004.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065004.1" } ] } }, { "isoform_ac": "A0A5G2R840-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840/entry#A0A5G2R840-1", "sequence": { "sequence": "MFARKSELHVLLFMVLAAKTAFGFSLLSLLTDLDPGFWPCPMPMLACCGHTKPLKRKHDALLLAASSVSEAGKTHWTPENYEYSYENYNQEENSSAPAHHENPDWYYTEDDPCLSNPCAHGGDCLVSGDTFTCSCPAPYSGNRCQKVQNKCKNKPCGRGECLITQSPPYYRCACKHPYRGPDCSTVVPVCRPNPCQNGGTCSRHRRRSKFTCTCPDQFKGRFCEIGSDDCYVGDGYSYRGEVSKTVNQHTCLYWNSHLLLQENYNMFMEDAEAHGIGEHNFCRNPDGDRKPWCFIKVSSAKVKWEYCDVPACSAPEGSPIEPVTELPGFDSCGRTETAERKFKRIYGGFKSTAGKHPWQASLQTSLHLTVSMPQGHFCGGALIHPCWVLTAAHCTDIKAKYLKVVLGDQDLKKTELHEQSFGVEKIFKHSRYREKDDIPYNDIALLKLKPVDGHCALESKYVKTVCLPDSPFPSGTECYISGWGVTETGEGSRQLLDAKVKLISNAVCNSRRLYDHMLDDNMICAGNLQKPGQDSCQGDSGGPLTCEKDDAYYVYGIVSWGLECGKKPGVYTQVTTFLNWIRATMEREASF", "length": 591, "header": "tr|A0A5G2R840-1|A0A5G2R840_PIG Isoform 1 of Factor VII-activating protease OS=Sus scrofa OX=9823 GN=HABP2 PE=1 SV=1 CANONICAL=A0A5G2R840-1" }, "locus": { "chromosome": "14", "start_pos": 123928255, "end_pos": 123894098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089340.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089340.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070282.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070282.1" } ] } }, { "isoform_ac": "A0A8W4F6U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840/entry#A0A8W4F6U9-1", "sequence": { "sequence": "MFARKSELHVLLFMVLAAKTAFGFSLLSLLTDLDPDWTPENYEYSYENYNQEENSSAPAHHENPDWYYTEDDPCLSNPCAHGGDCLVSGDTFTCSCPAPYSGNRCQKVQNKCKNKPCGRGECLITQSPPYYRCACKHPYRGPDCSTVVPVCRPNPCQNGGTCSRHRRRSKFTCTCPDQFKGRFCEIGSDDCYVGDGYSYRGEVSKTVNQHTCLYWNSHLLLQENYNMFMEDAEAHGIGEHNFCRNPDGDRKPWCFIKVSSAKVKWEYCDVPACSAPEGSPIEPVTELPGFDSCGRTETAERKFKRIYGGFKSTAGKHPWQASLQTSLHLTVSMPQGHFCGGALIHPCWVLTAAHCTDIKAKYLKVVLGDQDLKKTELHEQSFGVEKIFKHSRYREKDDIPYNDIALLKLKPVDGHCALESKYVKTVCLPDSPFPSGTECYISGWGVTETGEGSRQLLDAKVKLISNAVCNSRRLYDHMLDDNMICAGNLQKPGQDSCQSALGIQQGFKSQLLPPYEGTQQCSASLEPT", "length": 528, "header": "tr|A0A8W4F6U9-1|A0A5G2R840_PIG Computationally mapped isoform of Factor VII-activating protease OS=Sus scrofa OX=9823 GN=HABP2 PE=1 SV=1 CANONICAL=A0A5G2R840-1" }, "locus": { "chromosome": "14", "start_pos": 123926605, "end_pos": 123894098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103004.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103004.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074972.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074972.1" } ] } }, { "isoform_ac": "F1S5J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840/entry#F1S5J5-1", "sequence": { "sequence": "MPMLACCGHTKPLKRKHDALLLAASSVSEAGKTHWTPENYEYSYENYNQEENSSAPAHHENPDWYYTEDDPCLSNPCAHGGDCLVSGDTFTCSCPAPYSGNRCQKVQNKCKNKPCGRGECLITQSPPYYRCACKHPYRGPDCSTVVPVCRPNPCQNGGTCSRHRRRSKFTCTCPDQFKGRFCEIGSDDCYVGDGYSYRGEVSKTVNQHTCLYWNSHLLLQENYNMFMEDAEAHGIGEHNFCRNPDGDRKPWCFIKVSSAKVKWEYCDVPACSAPEGSPIEPVTELPGFDSCGRTETAERKFKRIYGGFKSTAGKHPWQASLQTSLHLTVSMPQGHFCGGALIHPCWVLTAAHCTDIKAKYLKVVLGDQDLKKTELHEQSFGVEKIFKHSRYREKDDIPYNDIALLKLKPVDGHCALESKYVKTVCLPDSPFPSGTECYISGWGVTETGEGSRQLLDAKVKLISNAVCNSRRLYDHMLDDNMICAGNLQKPGQDSCQGDSGGPLTCEKDDAYYVYGIVSWGLECGKKPGVYTQVTTFLNWIRATMEREASF", "length": 550, "header": "tr|F1S5J5-1|A0A5G2R840_PIG Computationally mapped isoform of Factor VII-activating protease OS=Sus scrofa OX=9823 GN=HABP2 PE=1 SV=3 CANONICAL=A0A5G2R840-1" }, "locus": { "chromosome": "14", "start_pos": 123928255, "end_pos": 123913993, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011636.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011636.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011334.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011334.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R378", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R378" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R840", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R840", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R840", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R840", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R840", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840" } ], "pmid": "" }, { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R840", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R840-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 591, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R840-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R840" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 145, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840" }, { "id": "PS50070", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50070" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kringle", "eco_id": "ECO_0000259", "start_pos": 229, "end_pos": 312, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R840" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 345, "end_pos": 586, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RGQ4-1", "uniprot_ac": "A0A5G2RGQ4", "uniprot_id": "A0A5G2RGQ4_PIG", "mass": { "chemical_mass": 32758.0, "monoisotopic_mass": 32758.0 }, "refseq": {}, "gene_names": [ { "name": "NAPB", "type": "recommended", "evidence": [ { "id": "A0A5G2RGQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ] } ], "protein_names": [ { "name": "NSF attachment protein beta", "type": "synonym", "evidence": [ { "id": "A0A5G2RGQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QLD1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLD1#function" }, { "database": "UniProtKB", "id": "RU367013", "url": "https://www.uniprot.org/uniprotkb/RU367013#function" }, { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4#function" }, { "database": "UniProtKB", "id": "A0A287BD61", "url": "https://www.uniprot.org/uniprotkb/A0A287BD61#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NAPB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4", "locus": { "chromosome": "17", "start_pos": 30359420, "end_pos": 30396083, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031219", "url": "https://www.ensembl.org/id/ENSSSCG00000031219" } ] } } ], "crossref": [ { "id": "A0A5G2RGQ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGQ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000031219", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031219", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15832", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15832", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13768", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13768", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13768:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13768:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14938", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14938", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BD61", "url": "https://www.uniprot.org/uniprotkb/A0A287BD61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BD61-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BD61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLD1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSAAGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQAIDIYTDMGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNRQGSLCSGSCCSSANKCLLKVAAYAAQLEQYQKAIEVYEQVGASTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVSSPLRFCTSPDSSCYRNLFSFSLCKH", "length": 292, "header": "tr|A0A5G2RGQ4-1|A0A5G2RGQ4_PIG Isoform 1 of NSF attachment protein beta OS=Sus scrofa OX=9823 GN=NAPB PE=1 SV=2 CANONICAL=A0A5G2RGQ4-1" }, "isoforms": [ { "isoform_ac": "A0A287BD61-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4/entry#A0A287BD61-1", "sequence": { "sequence": "MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSAAGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEVYEQVGASTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRECKLLKVKEFDSISRLDQWLTTMLLRIKKSIPGDGDGDGDLK", "length": 281, "header": "tr|A0A287BD61-1|A0A287BD61_PIG Computationally mapped isoform of NSF attachment protein beta OS=Sus scrofa OX=9823 GN=NAPB PE=1 SV=3 CANONICAL=A0A5G2RGQ4-1" }, "locus": { "chromosome": "17", "start_pos": 30396005, "end_pos": 30363993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050677.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050677.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054481.3", "url": "https://www.ensembl.org/id/ENSSSCP00000054481.3" } ] } }, { "isoform_ac": "A0A5G2QLD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4/entry#A0A5G2QLD1-1", "sequence": { "sequence": "MHQRGVCPECPHRHCCPGTWPPWGWGVAPGAPVCVNSGLCLQLQETHFVRRPSSTCSCRANTTRPPALWMPGTPTRRQTRKGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEVYEQVGASTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIPGDGDGDGDLK", "length": 265, "header": "tr|A0A5G2QLD1-1|A0A5G2RGQ4_PIG Computationally mapped isoform of NSF attachment protein beta OS=Sus scrofa OX=9823 GN=NAPB PE=1 SV=2 CANONICAL=A0A5G2RGQ4-1" }, "locus": { "chromosome": "17", "start_pos": 30377780, "end_pos": 30363993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076240.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076240.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065631.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065631.2" } ] } }, { "isoform_ac": "A0A5G2RGQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4/entry#A0A5G2RGQ4-1", "sequence": { "sequence": "MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSAAGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQAIDIYTDMGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNRQGSLCSGSCCSSANKCLLKVAAYAAQLEQYQKAIEVYEQVGASTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVSSPLRFCTSPDSSCYRNLFSFSLCKH", "length": 292, "header": "tr|A0A5G2RGQ4-1|A0A5G2RGQ4_PIG Isoform 1 of NSF attachment protein beta OS=Sus scrofa OX=9823 GN=NAPB PE=1 SV=2 CANONICAL=A0A5G2RGQ4-1" }, "locus": { "chromosome": "17", "start_pos": 30396005, "end_pos": 30364904, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069570.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069570.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070424.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070424.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QLD1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLD1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-SSC-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-SSC-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-SSC-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" }, { "id": "R-SSC-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ], "pmid": "" }, { "name": "SNARE complex disassembly", "id": "GO:0035494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035494", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ], "pmid": "" }, { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle priming", "id": "GO:0010807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010807", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ], "pmid": "" }, { "name": "synaptobrevin 2-SNAP-25-syntaxin-1a complex", "id": "GO:0070044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070044", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ], "pmid": "" }, { "name": "soluble NSF attachment protein activity", "id": "GO:0005483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005483", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RGQ4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 292, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RGQ4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGQ4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RGD4-1", "uniprot_ac": "A0A5G2RGD4", "uniprot_id": "A0A5G2RGD4_PIG", "mass": { "chemical_mass": 27520.0, "monoisotopic_mass": 27520.0 }, "refseq": {}, "gene_names": [ { "name": "NECAP1", "type": "recommended", "evidence": [ { "id": "A0A5G2RGD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4" } ] }, { "name": "LOC110260747", "type": "synonym", "evidence": [ { "id": "A0A5G2RGD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4" } ] } ], "protein_names": [ { "name": "C-type lectin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RGD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NECAP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4", "locus": { "chromosome": "5", "start_pos": 63139664, "end_pos": 63122335, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000025179", "url": "https://www.ensembl.org/id/ENSSSCG00000025179" } ] } } ], "crossref": [ { "id": "A0A5G2RGD4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGD4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000025179", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000025179", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03590", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03590", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110260747", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110260747", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RGD4", "url": "https://www.orthodb.org/?gene=A0A5G2RGD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22803", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22803", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46746", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46746", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46746:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46746:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287BE29", "url": "https://www.uniprot.org/uniprotkb/A0A287BE29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BE29-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BE29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAV9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSEITYAEVRFKNEPKSSGTKSEPPTAPKEKTNPQKSDSSFPKLLASLLILLLLLTISFLIAFIFFFQKYSHIHKEKTTLKEVPHRALECMKENLTMEDKDWSCCPKNWTSFGSNCYFISVESGTWDESEKKCSSVKTHLLVITAKAEQEFIIQKLDKSSAYYVGLSDLQGKNNWQWVDQTPYNESATFWHSGEPNDLSEHCVILHFRASPRKWGWNDVRCNQHQKFICKMMKIYL", "length": 237, "header": "tr|A0A5G2RGD4-1|A0A5G2RGD4_PIG Isoform 1 of C-type lectin domain-containing protein OS=Sus scrofa OX=9823 GN=NECAP1 PE=4 SV=1 CANONICAL=A0A5G2RGD4-1" }, "isoforms": [ { "isoform_ac": "A0A287BE29-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4/entry#A0A287BE29-1", "sequence": { "sequence": "MNSEITYAEVRFKNEPKSSGTKSEPPTVFFQKYSHIHKEKTTLKEVPHRALECMKENLTMEDKDWSCCPKNWTSFGSNCYFISVESGTWDESEKKCSSVKTHLLVITAKAEQEFIIQKLDKSSAYYVGLSDLQGKNNWQWVDQTPYNESATFWHSGEPNDLSEHCVILHFRASPRKWGWNDVRCNQHQKFICKMMKIYL", "length": 199, "header": "tr|A0A287BE29-1|A0A287BE29_PIG Computationally mapped isoform of C-type lectin domain-containing protein OS=Sus scrofa OX=9823 GN=NECAP1 PE=4 SV=2 CANONICAL=A0A5G2RGD4-1" }, "locus": { "chromosome": "5", "start_pos": 63184237, "end_pos": 63157378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039656.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039656.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054799.2", "url": "https://www.ensembl.org/id/ENSSSCP00000054799.2" } ] } }, { "isoform_ac": "A0A5G2RAV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4/entry#A0A5G2RAV9-1", "sequence": { "sequence": "MNSEITYAEVRFKNEPKSSGTKSEPPTDKDWSCCPKNWTSFGSNCYFISVESGTWDESEKKCSSVKTHLLVITAKAEQEFIIQKLDKSSAYYVGLSDLQGKNNWQWVDQTPYNESATFWHSGEPNDLSEHCVILHFRASPRKWGWNDVRCNQHQKFICKMMKIYL", "length": 165, "header": "tr|A0A5G2RAV9-1|A0A5G2RGD4_PIG Computationally mapped isoform of C-type lectin domain-containing protein OS=Sus scrofa OX=9823 GN=NECAP1 PE=4 SV=2 CANONICAL=A0A5G2RGD4-1" }, "locus": { "chromosome": "5", "start_pos": 63184237, "end_pos": 63157378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083880.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083880.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067743.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067743.2" } ] } }, { "isoform_ac": "A0A5G2RGD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4/entry#A0A5G2RGD4-1", "sequence": { "sequence": "MNSEITYAEVRFKNEPKSSGTKSEPPTAPKEKTNPQKSDSSFPKLLASLLILLLLLTISFLIAFIFFFQKYSHIHKEKTTLKEVPHRALECMKENLTMEDKDWSCCPKNWTSFGSNCYFISVESGTWDESEKKCSSVKTHLLVITAKAEQEFIIQKLDKSSAYYVGLSDLQGKNNWQWVDQTPYNESATFWHSGEPNDLSEHCVILHFRASPRKWGWNDVRCNQHQKFICKMMKIYL", "length": 237, "header": "tr|A0A5G2RGD4-1|A0A5G2RGD4_PIG Isoform 1 of C-type lectin domain-containing protein OS=Sus scrofa OX=9823 GN=NECAP1 PE=4 SV=1 CANONICAL=A0A5G2RGD4-1" }, "locus": { "chromosome": "5", "start_pos": 63184237, "end_pos": 63157378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074389.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074389.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070254.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070254.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 27, "start_aa": "Thr", "end_pos": 27, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr27", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAV9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAV9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110260747", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110260747", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RGD4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 237, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RGD4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGD4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RGD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGD4" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 113, "end_pos": 231, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 27 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RBM6-1", "uniprot_ac": "A0A5G2RBM6", "uniprot_id": "A0A5G2RBM6_PIG", "mass": { "chemical_mass": 49991.0, "monoisotopic_mass": 49991.0 }, "refseq": {}, "gene_names": [ { "name": "GLRX3", "type": "recommended", "evidence": [ { "id": "A0A5G2RBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6" } ] } ], "protein_names": [ { "name": "Glutaredoxin 3", "type": "synonym", "evidence": [ { "id": "A0A5G2RBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins. Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator. Required for hemoglobin maturation. Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BFB8", "url": "https://www.uniprot.org/uniprotkb/A0A287BFB8#function" }, { "database": "UniProtKB", "id": "ARBA00058718", "url": "https://www.uniprot.org/uniprotkb/ARBA00058718#function" }, { "database": "UniProtKB", "id": "F1SDJ8", "url": "https://www.uniprot.org/uniprotkb/F1SDJ8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GLRX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6", "locus": { "chromosome": "14", "start_pos": 139111249, "end_pos": 139072575, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010759", "url": "https://www.ensembl.org/id/ENSSSCG00000010759" } ] } } ], "crossref": [ { "id": "A0A5G2RBM6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010759", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010759", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02984", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02984", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03028", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03028", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "F1SDJ8", "url": "https://www.ebi.ac.uk/intact/interactors/id:F1SDJ8*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004480", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004480", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10293", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10293", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10293:SF73", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10293:SF73", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287BFB8", "url": "https://www.uniprot.org/uniprotkb/A0A287BFB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BFB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BFB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ71-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SDJ8", "url": "https://www.uniprot.org/uniprotkb/F1SDJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SDJ8-1", "url": "https://www.uniprot.org/uniprotkb/F1SDJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHIQSFFTSIVLWLQSSSFRLSCLEISCTLWVYRSLLVVHFWAPWAPQCAQMNDVMAELAKEHPQVSFVKLEAEAVPEVSEKYGISSVPTFLFFKNSQSIDRLDGAHAPELTKKVQRHASSSSFPSGGSEHLKEDLSLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILNKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASKELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQVKNSKMVLFVISFDVNVRQGLKTYSNWPTYPQLYVKGELVGGLDIVKVRVEFPCHSGELKTRACLKRSLPWARSCLASCLITSGPAPPSLRLTYPGPPSPPRAGPVSCLTARPLLQAGPFRTSSSAGSLPALVPRVTRHSEQLGVWPGSELCQVLTRLSLPSPSASGSLALSILFWSFQGRTCGIWRFPG", "length": 450, "header": "tr|A0A5G2RBM6-1|A0A5G2RBM6_PIG Isoform 1 of Glutaredoxin 3 OS=Sus scrofa OX=9823 GN=GLRX3 PE=1 SV=2 CANONICAL=A0A5G2RBM6-1" }, "isoforms": [ { "isoform_ac": "A0A287BFB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6/entry#A0A287BFB8-1", "sequence": { "sequence": "MAAGAAEAAAAVVEVGSAGQFEELLRLRAKSLLVVHFWAPWAPQCAQMNDVMAELAKEHPQVSFVKTKTPKSYFLKPEFVSSEDVLLEAEAVPEVSEKYGISSVPTFLFFKNSQSIDRLDGAHAPELTKKVQRHASSSSFPSGGSEHLKEDLSLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILNKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASKELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSRQILEILNSTGVDYETFDILEDEEVRQGLKTYSNWPTYPQLYVKGELVGGLDIVKELKENGELLPILKGEN", "length": 354, "header": "tr|A0A287BFB8-1|A0A287BFB8_PIG Computationally mapped isoform of PKC-interacting cousin of thioredoxin OS=Sus scrofa OX=9823 GN=GLRX3 PE=1 SV=2 CANONICAL=A0A5G2RBM6-1" }, "locus": { "chromosome": "14", "start_pos": 139107861, "end_pos": 139072608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059632.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059632.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036593.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036593.2" } ] } }, { "isoform_ac": "A0A5G2QQ71-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6/entry#A0A5G2QQ71-1", "sequence": { "sequence": "MHIQSFFTSIVLWLQSSSFRLSCLEISCTLWVYRSLLVVHFWAPWAPQCAQMNDVMAELAKEHPQVSFVKLEAEAVPEVSEKYGISSVPTFLFFKNSQSIDRLDGAHAPELTKKVQRHASSSSFPSGGSEHLKEDLSLRLKKLTHAAPCMLFMKGTPQEPRCASFYSHSLDSAVYRIVDSCRSAVGKGPDYSGLGRLEGFSKQMVEILNKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASKELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQVKNSKMVLFVISFDVNTFDILEDEEVRQGLKTYSNWPTYPQLYVKGELVGGLDIVKQLCAPVLSG", "length": 361, "header": "tr|A0A5G2QQ71-1|A0A5G2RBM6_PIG Computationally mapped isoform of Glutaredoxin 3 OS=Sus scrofa OX=9823 GN=GLRX3 PE=1 SV=2 CANONICAL=A0A5G2RBM6-1" }, "locus": { "chromosome": "14", "start_pos": 139104504, "end_pos": 139079070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076641.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076641.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067041.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067041.2" } ] } }, { "isoform_ac": "A0A5G2RBM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6/entry#A0A5G2RBM6-1", "sequence": { "sequence": "MHIQSFFTSIVLWLQSSSFRLSCLEISCTLWVYRSLLVVHFWAPWAPQCAQMNDVMAELAKEHPQVSFVKLEAEAVPEVSEKYGISSVPTFLFFKNSQSIDRLDGAHAPELTKKVQRHASSSSFPSGGSEHLKEDLSLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILNKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASKELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQVKNSKMVLFVISFDVNVRQGLKTYSNWPTYPQLYVKGELVGGLDIVKVRVEFPCHSGELKTRACLKRSLPWARSCLASCLITSGPAPPSLRLTYPGPPSPPRAGPVSCLTARPLLQAGPFRTSSSAGSLPALVPRVTRHSEQLGVWPGSELCQVLTRLSLPSPSASGSLALSILFWSFQGRTCGIWRFPG", "length": 450, "header": "tr|A0A5G2RBM6-1|A0A5G2RBM6_PIG Isoform 1 of Glutaredoxin 3 OS=Sus scrofa OX=9823 GN=GLRX3 PE=1 SV=2 CANONICAL=A0A5G2RBM6-1" }, "locus": { "chromosome": "14", "start_pos": 139103775, "end_pos": 139079070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091125.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091125.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071576.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071576.2" } ] } }, { "isoform_ac": "A0A5G2RFG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6/entry#A0A5G2RFG3-1", "sequence": { "sequence": "MAAGAAEAAAAVVEVGSAGQFEELLRLRAKSLLVVHFWAPWAPQCAQMNDVMAELAKEHPQVSFVKLEAEAVPEVSEKYGISSVPTFLFFKNSQSIDRLDGAHAPELTKKVQRHASSSSFPSGGSEHLKEDLSLRLKKLTHAAPCMLFMKGTPQEPRCASFYSHSLDSAVYRIVDSCRSAVGKGPDYSGLGRLEGFSKQMVEILNKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASKELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSRQILEILNSTGVDYETFDILEDEEVRQGLKTYSNWPTYPQLYVKGELVGGLDIVKELKENGELLPILKGEN", "length": 370, "header": "tr|A0A5G2RFG3-1|A0A5G2RBM6_PIG Computationally mapped isoform of Glutaredoxin 3 OS=Sus scrofa OX=9823 GN=GLRX3 PE=1 SV=1 CANONICAL=A0A5G2RBM6-1" }, "locus": { "chromosome": "14", "start_pos": 139107861, "end_pos": 139072608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084828.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084828.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069759.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069759.1" } ] } }, { "isoform_ac": "F1SDJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6/entry#F1SDJ8-1", "sequence": { "sequence": "MAAGAAEAAAAVVEVGSAGQFEELLRLRAKSLLVVHFWAPWAPQCAQMNDVMAELAKEHPQVSFVKLEAEAVPEVSEKYGISSVPTFLFFKNSQSIDRLDGAHAPELTKKVQRHASSSSFPSGGSEHLKEDLSLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILNKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASKELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSRQILEILNSTGFRNCACAHSLPAGIQSYSHTRFQKMCVDYETFDILEDEEVRQGLKTYSNWPTYPQLYVKGELVGGLDIVKELKENGELLPILKGEN", "length": 360, "header": "tr|F1SDJ8-1|A0A5G2RBM6_PIG Computationally mapped isoform of Glutaredoxin 3 OS=Sus scrofa OX=9823 GN=GLRX3 PE=1 SV=2 CANONICAL=A0A5G2RBM6-1" }, "locus": { "chromosome": "14", "start_pos": 139107861, "end_pos": 139072608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011771.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011771.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011469.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011469.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ71" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6" } ], "pmid": "" }, { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6" } ], "pmid": "" }, { "name": "[2Fe-2S] cluster assembly", "id": "GO:0044571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044571", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RBM6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 450, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RBM6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBM6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM6" }, { "id": "PS51352", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 120, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RBT2-1", "uniprot_ac": "A0A5G2RBT2", "uniprot_id": "A0A5G2RBT2_PIG", "mass": { "chemical_mass": 18503.0, "monoisotopic_mass": 18503.0 }, "refseq": {}, "gene_names": [ { "name": "AVP", "type": "recommended", "evidence": [ { "id": "A0A5G2RBT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ] } ], "protein_names": [ { "name": "Vasopressin", "type": "synonym", "evidence": [ { "id": "A0A5G2RBT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels. Acts by binding to vasopressin receptors (V1bR/AVPR1B, V1aR/AVPR1A, and V2R/AVPR2).", "evidence": [ { "database": "UniProtKB", "id": "A0A480NN46", "url": "https://www.uniprot.org/uniprotkb/A0A480NN46#function" }, { "database": "UniProtKB", "id": "ARBA00094417", "url": "https://www.uniprot.org/uniprotkb/ARBA00094417#function" } ] }, { "annotation": "Specifically binds vasopressin.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2#function" }, { "database": "UniProtKB", "id": "ARBA00094240", "url": "https://www.uniprot.org/uniprotkb/ARBA00094240#function" }, { "database": "UniProtKB", "id": "A0A480NN46", "url": "https://www.uniprot.org/uniprotkb/A0A480NN46#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AVP", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2", "locus": { "chromosome": "17", "start_pos": 32583185, "end_pos": 32581234, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007163", "url": "https://www.ensembl.org/id/ENSSSCG00000007163" } ] } } ], "crossref": [ { "id": "A0A5G2RBT2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBT2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000007163", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007163", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CMTEPEC", "url": "https://omabrowser.org/oma/group/CMTEPEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11681", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11681", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11681:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11681:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00220", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00220", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A480NN46", "url": "https://www.uniprot.org/uniprotkb/A0A480NN46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480NN46-1", "url": "https://www.uniprot.org/uniprotkb/A0A480NN46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LLTARLRPLSGPKQCQRPDPPALPCPAQPLAQQGLPPQPGPLPDPGSPLPFRQCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGASFLRRARASDRSNATLLDGPSGALLLRLVQLAGAPEPAEPVQPGVY", "length": 179, "header": "tr|A0A5G2RBT2-1|A0A5G2RBT2_PIG Isoform 1 of Vasopressin OS=Sus scrofa OX=9823 GN=AVP PE=3 SV=1 CANONICAL=A0A5G2RBT2-1" }, "isoforms": [ { "isoform_ac": "A0A480NN46-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2/entry#A0A480NN46-1", "sequence": { "sequence": "MPDATLPACFLGLLALTSACYFQNCPKGGKRAMSDLELRQCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGASFLRRARASDRSNATLLDGPSGALLLRLVQLAGAPEPAEPVQPGVY", "length": 166, "header": "tr|A0A480NN46-1|A0A480NN46_PIG Computationally mapped isoform of Vasopressin OS=Sus scrofa OX=9823 GN=AVP PE=3 SV=1 CANONICAL=A0A5G2RBT2-1" }, "locus": { "chromosome": "17", "start_pos": 32583120, "end_pos": 32581278, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101457.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101457.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080747.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080747.1" } ] } }, { "isoform_ac": "A0A5G2RBT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2/entry#A0A5G2RBT2-1", "sequence": { "sequence": "LLTARLRPLSGPKQCQRPDPPALPCPAQPLAQQGLPPQPGPLPDPGSPLPFRQCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGASFLRRARASDRSNATLLDGPSGALLLRLVQLAGAPEPAEPVQPGVY", "length": 179, "header": "tr|A0A5G2RBT2-1|A0A5G2RBT2_PIG Isoform 1 of Vasopressin OS=Sus scrofa OX=9823 GN=AVP PE=3 SV=1 CANONICAL=A0A5G2RBT2-1" }, "locus": { "chromosome": "17", "start_pos": 32583120, "end_pos": 32582431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085578.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085578.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071637.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071637.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P01180-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPDATLPACFLSLLAFTSACYFQNCPRGGKRAMSDLELRQCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGVGFPRRVRANDRSNATLLDGPSGALLLRLVQLAGAPEPAEPAQPGVY", "length": 166 }, "evidence": [ { "id": "A0A5G2RBT2", "url": "https://omabrowser.org/oma/group/A0A5G2RBT2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPDTMLPACFLGLLAFSSACYFQNCPRGGKRAMSDLELRQCLPCGPGGKGRCFGPSICCADELGCFVGTAEALRCQEENYLPSPCQSGQKACGSGGRCAAFGVCCNDESCVTEPECREGFHRRARASDRSNATQLDGPAGALLLRLVQLAGAPEPFEPAQPDAY", "length": 164 }, "evidence": [ { "id": "A0A5G2RBT2", "url": "https://omabrowser.org/oma/group/A0A5G2RBT2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P01186-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "Avp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAMMLNTTLSACFLSLLALTSACYFQNCPRGGKRATSDMELRQCLPCGPGGKGRCFGPSICCADELGCFLGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCSDESCVAEPECREGFFRLTRAREQSNATQLDGPARELLLRLVQLAGTQESVDSAKPRVY", "length": 168 }, "evidence": [ { "id": "A0A5G2RBT2", "url": "https://omabrowser.org/oma/group/A0A5G2RBT2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24787-1", "protein_name": "Vasotocin-neurophysin VT", "gene_name": "", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEPSLPLSFLCLLALSSACYIQNCPRGGKRALGDTALRQCLPCGPGNRGRCFGPGICCGAELGCYLGTAETRRCAEEDYMPSPCQAGGQPCGSDGRCAANGVCCSADTCAMDAVCLEEGSEQAEEAAEKNLTVLDGAAGDLLLRLMHLANRQQQGKQPGL", "length": 161 }, "evidence": [ { "id": "A0A5G2RBT2", "url": "https://omabrowser.org/oma/group/A0A5G2RBT2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "neurohypophyseal hormone activity", "id": "GO:0005185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005185", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "pmid": "" }, { "name": "V1A vasopressin receptor binding", "id": "GO:0031894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031894", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "pmid": "" }, { "name": "neuropeptide hormone activity", "id": "GO:0005184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005184", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "vasoconstriction", "id": "GO:0042310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042310", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "pmid": "" }, { "name": "maternal aggressive behavior", "id": "GO:0002125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002125", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "pmid": "" }, { "name": "positive regulation of systemic arterial blood pressure", "id": "GO:0003084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003084", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "pmid": "" }, { "name": "positive regulation of vasoconstriction", "id": "GO:0045907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045907", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RBT2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 179, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RBT2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBT2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R6Z3-1", "uniprot_ac": "A0A5G2R6Z3", "uniprot_id": "A0A5G2R6Z3_PIG", "mass": { "chemical_mass": 89541.0, "monoisotopic_mass": 89541.0 }, "refseq": { "ac": "XP_020919135", "name": "semaphorin-3D", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919135" }, "gene_names": [ { "name": "SEMA3D", "type": "recommended", "evidence": [ { "id": "A0A5G2R6Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ] }, { "name": "SEMA3D", "type": "synonym", "evidence": [ { "id": "XP_020919135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919135" } ] } ], "protein_names": [ { "name": "Semaphorin 3D", "type": "synonym", "evidence": [ { "id": "A0A5G2R6Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3/entry#names_and_taxonomy" } ] }, { "name": "semaphorin-3D", "type": "synonym", "evidence": [ { "id": "XP_020919135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919135" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SEMA3D", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3", "locus": { "chromosome": "9", "start_pos": 95486090, "end_pos": 95280593, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015396", "url": "https://www.ensembl.org/id/ENSSSCG00000015396" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015396", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015396", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05871", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05871", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11252", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11252", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523915", "url": "https://www.ncbi.nlm.nih.gov/gene/100523915", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523915", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523915", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R6Z3", "url": "https://www.orthodb.org/?gene=A0A5G2R6Z3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18452", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18452", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020919135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919135", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SNH3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SNH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIVNKNERPRSRSHDFYLFHALVMLSMTTLFLPVTGTSKQNIPRLKLTYKDLLLSNSCIPFLGSSEGLDFQTILLDEERGRLLLGAKDHIFLLSLVDLNKNFKKIYWPAAKERVELCKLAGKDANTECANFIRVLQPYNKTHVYVCGTGAFHPICGYIDLGAYKEEVMFKLDTHNLESGRLKCPFDPQQPFASVMTDEYLYSGTASDFLGKDTAFTRSLGPTHDHHYIRTDISEHHWLNGAKFIGTFSIPDTYNPDDDKIYFFFRESSQEGSTSDKTILSRVGRVCKNDVGGQRSLINKWTTFLKARLICSIPGSDGADTHFDELQDIYLLPTRDERNPVVYGVFTTTSSIFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQYDGRIPYPRPGTCPSRTYDPLIKSTRDFPDDVISFIKRHPVMYKSVYPVVGGPTFKRINVDYRLTQIVVDHVVAEDGQYDVMFLGTDIGTVLKVVSISKEKWNMEEVVLEELQIFKHSSMILNMELSLKQQQLYIGSRDGLVQLSLHRCDTYGKACAECCLARDPYCAWDGNACSRYAPTSKRRARRQDVKYGDPITQCWDIEDSISHEAADEKVIFGIEFNSTFLECIPKSQQASIKWYLQRSGDEHREELKPDERIIKTEYGLLIRSLQKKDSGMYYCKAQEHTFIHTVVKLTLNVIENEQMENTQRAEHEEGRVKDLLAESRLRYKDYIQILSSPNFSLDQYCEQMWHREKRRQRNKGGPKWKHMQEMKKKRNRRHHRDLDELPSAVAT", "length": 777, "header": "tr|A0A5G2R6Z3-1|A0A5G2R6Z3_PIG Isoform 1 of Semaphorin 3D OS=Sus scrofa OX=9823 GN=SEMA3D PE=3 SV=1 CANONICAL=A0A5G2R6Z3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SNH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3/entry#A0A4X1SNH3-1", "sequence": { "sequence": "MIVNKNERPRSRSHDFYLFHALVMLSMTTLFLPVTGTSKQNIPRLKLTYKDLLLSNSCIPFLGSSEGLDFQTILLDEERGRLLLGAKDHIFLLSLVDLNKNFKKIYWPAAKERVELCKLAGKDANTECANFIRVLQPYNKTHVYVCGTGAFHPICGYIDLGAYKEEVMFKLDTHNLESGRLKCPFDPQQPFASVMTDEYLYSGTASDFLGKDTAFTRSLGPTHDHHYIRTDISEHHWLNGAKFIGTFSIPDTYNPDDDKIYFFFRESSQEGSTSDKTILSRVGRVCKNFLYFEGG", "length": 295, "header": "tr|A0A4X1SNH3-1|A0A4X1SNH3_PIG Computationally mapped isoform of Semaphorin 3D OS=Sus scrofa OX=9823 GN=SEMA3D PE=4 SV=1 CANONICAL=A0A5G2R6Z3-1" }, "locus": { "chromosome": "9", "start_pos": 95423502, "end_pos": 95347058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025180.3", "url": "https://www.ensembl.org/id/ENSSSCT00000025180.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026440.3", "url": "https://www.ensembl.org/id/ENSSSCP00000026440.3" } ] } }, { "isoform_ac": "A0A5G2R6Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3/entry#A0A5G2R6Z3-1", "sequence": { "sequence": "MIVNKNERPRSRSHDFYLFHALVMLSMTTLFLPVTGTSKQNIPRLKLTYKDLLLSNSCIPFLGSSEGLDFQTILLDEERGRLLLGAKDHIFLLSLVDLNKNFKKIYWPAAKERVELCKLAGKDANTECANFIRVLQPYNKTHVYVCGTGAFHPICGYIDLGAYKEEVMFKLDTHNLESGRLKCPFDPQQPFASVMTDEYLYSGTASDFLGKDTAFTRSLGPTHDHHYIRTDISEHHWLNGAKFIGTFSIPDTYNPDDDKIYFFFRESSQEGSTSDKTILSRVGRVCKNDVGGQRSLINKWTTFLKARLICSIPGSDGADTHFDELQDIYLLPTRDERNPVVYGVFTTTSSIFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQYDGRIPYPRPGTCPSRTYDPLIKSTRDFPDDVISFIKRHPVMYKSVYPVVGGPTFKRINVDYRLTQIVVDHVVAEDGQYDVMFLGTDIGTVLKVVSISKEKWNMEEVVLEELQIFKHSSMILNMELSLKQQQLYIGSRDGLVQLSLHRCDTYGKACAECCLARDPYCAWDGNACSRYAPTSKRRARRQDVKYGDPITQCWDIEDSISHEAADEKVIFGIEFNSTFLECIPKSQQASIKWYLQRSGDEHREELKPDERIIKTEYGLLIRSLQKKDSGMYYCKAQEHTFIHTVVKLTLNVIENEQMENTQRAEHEEGRVKDLLAESRLRYKDYIQILSSPNFSLDQYCEQMWHREKRRQRNKGGPKWKHMQEMKKKRNRRHHRDLDELPSAVAT", "length": 777, "header": "tr|A0A5G2R6Z3-1|A0A5G2R6Z3_PIG Isoform 1 of Semaphorin 3D OS=Sus scrofa OX=9823 GN=SEMA3D PE=3 SV=1 CANONICAL=A0A5G2R6Z3-1" }, "locus": { "chromosome": "9", "start_pos": 95482198, "end_pos": 95347058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091185.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091185.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073022.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073022.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523915", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523915", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ], "pmid": "" }, { "name": "neuropilin binding", "id": "GO:0038191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038191", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ], "pmid": "" }, { "name": "chemorepellent activity", "id": "GO:0045499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045499", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ], "pmid": "" }, { "name": "negative chemotaxis", "id": "GO:0050919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050919", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 724, "end_pos": 726, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R6Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 611, "end_pos": 680, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R6Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Z3" }, { "id": "PS51004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sema", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 531, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 607, "end_pos": 609 }, { "start_pos": 724, "end_pos": 726 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2REY5-1", "uniprot_ac": "A0A5G2REY5", "uniprot_id": "A0A5G2REY5_PIG", "mass": { "chemical_mass": 124005.0, "monoisotopic_mass": 124005.0 }, "refseq": {}, "gene_names": [ { "name": "FMNL2", "type": "recommended", "evidence": [ { "id": "A0A5G2REY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" } ] } ], "protein_names": [ { "name": "Formin like 2", "type": "synonym", "evidence": [ { "id": "A0A5G2REY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REY5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FMNL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5", "locus": { "chromosome": "15", "start_pos": 60384655, "end_pos": 60053877, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015866", "url": "https://www.ensembl.org/id/ENSSSCG00000015866" } ] } } ], "crossref": [ { "id": "A0A5G2REY5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2REY5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015866", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015866", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR010472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043592", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043592", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45857", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45857", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45857:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45857:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06367", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06367", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06371", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06371", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1VTH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VTH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REY5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSNLPSPVGSSASRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPVVASGTLPTGSEVAVGNFVGPVSGAASSGPLPPPPPPLPLSSDAPEAVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPLPGPAADTVPAPPLPPPPPPSAPPLPGTSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKITQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPVENLSDEDRFMMQFSKIERLMQKMTIMAFIGNFAESIQMLTPQLHSIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFIFNNEGKLKKLQDDAKIAQDAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALLDQQDPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRSVRRRFDDQNLRSVNGAEITM", "length": 1092, "header": "tr|A0A5G2REY5-1|A0A5G2REY5_PIG Isoform 1 of Formin like 2 OS=Sus scrofa OX=9823 GN=FMNL2 PE=3 SV=1 CANONICAL=A0A5G2REY5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1VTH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5/entry#A0A4X1VTH0-1", "sequence": { "sequence": "MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSNLPSPVGSSASRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPVVASGTLPTGSEVAVGNFVGPVSGAASSGPLPPPPPPLPLSSDAPEAVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPLPGPAADTVPAPPLPPPPPPSAPPLPGTSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKITQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPVENLSDEDRFMMQFSKIERLMQKMTIMAFIGNFAESIQMLTPQLHSIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFIFNNEGKLKKLQDDAKIAQDAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALLDQQDPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITVLKTVPFTARTAKRGSRFFCEPVLTEEYHY", "length": 1086, "header": "tr|A0A4X1VTH0-1|A0A5G2REY5_PIG Computationally mapped isoform of Formin like 2 OS=Sus scrofa OX=9823 GN=FMNL2 PE=3 SV=2 CANONICAL=A0A5G2REY5-1" }, "locus": { "chromosome": "15", "start_pos": 60378838, "end_pos": 60054300, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070042.3", "url": "https://www.ensembl.org/id/ENSSSCT00000070042.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065342.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065342.2" } ] } }, { "isoform_ac": "A0A5G2REY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5/entry#A0A5G2REY5-1", "sequence": { "sequence": "MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSNLPSPVGSSASRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPVVASGTLPTGSEVAVGNFVGPVSGAASSGPLPPPPPPLPLSSDAPEAVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPLPGPAADTVPAPPLPPPPPPSAPPLPGTSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKITQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPVENLSDEDRFMMQFSKIERLMQKMTIMAFIGNFAESIQMLTPQLHSIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFIFNNEGKLKKLQDDAKIAQDAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALLDQQDPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRSVRRRFDDQNLRSVNGAEITM", "length": 1092, "header": "tr|A0A5G2REY5-1|A0A5G2REY5_PIG Isoform 1 of Formin like 2 OS=Sus scrofa OX=9823 GN=FMNL2 PE=3 SV=1 CANONICAL=A0A5G2REY5-1" }, "locus": { "chromosome": "15", "start_pos": 60382708, "end_pos": 60054300, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076394.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076394.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073266.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073266.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 549, "start_aa": "Thr", "end_pos": 549, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr549", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VTH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTH0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-SSC-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REY5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REY5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REY5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REY5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" } ], "pmid": "" }, { "name": "regulation of cell morphogenesis", "id": "GO:0022604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022604", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REY5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REY5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REY5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REY5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REY5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 640, "end_pos": 642, "annotation": "n_glycosylation_sequon" }, { "start_pos": 761, "end_pos": 763, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 835, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2REY5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1092, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2REY5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2REY5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2REY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" }, { "id": "PS51231", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51231" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DAD", "eco_id": "ECO_0000259", "start_pos": 1039, "end_pos": 1078, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2REY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" }, { "id": "PS51444", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51444" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FH2", "eco_id": "ECO_0000259", "start_pos": 616, "end_pos": 1007, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2REY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY5" }, { "id": "PS51232", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51232" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GBD/FH3", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 469, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 549 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 401, "end_pos": 403 }, { "start_pos": 640, "end_pos": 642 }, { "start_pos": 761, "end_pos": 763 }, { "start_pos": 833, "end_pos": 835 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2REF7-1", "uniprot_ac": "A0A5G2REF7", "uniprot_id": "A0A5G2REF7_PIG", "mass": { "chemical_mass": 12389.0, "monoisotopic_mass": 12389.0 }, "refseq": { "ac": "NP_001231793", "name": "mitochondrial pyruvate carrier 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231793" }, "gene_names": [ { "name": "MPC1", "type": "recommended", "evidence": [ { "id": "A0A5G2REF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7" } ] }, { "name": "BRP44L", "type": "synonym", "evidence": [ { "id": "NP_001231793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231793" } ] }, { "name": "MPC1", "type": "synonym", "evidence": [ { "id": "NP_001231793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231793" } ] } ], "protein_names": [ { "name": "Mitochondrial pyruvate carrier", "type": "recommended", "evidence": [ { "id": "A0A5G2REF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial pyruvate carrier 1", "type": "synonym", "evidence": [ { "id": "NP_001231793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231793" } ] } ], "function": [ { "annotation": "Mediates the uptake of pyruvate into mitochondria.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VWR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VWR3#function" }, { "database": "UniProtKB", "id": "RU363100", "url": "https://www.uniprot.org/uniprotkb/RU363100#function" }, { "database": "UniProtKB", "id": "A0A5G2R834", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R834#function" }, { "database": "UniProtKB", "id": "A0A5G2REF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MPC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7", "locus": {} } ], "crossref": [ { "id": "A0A5G2REF7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2REF7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000032916", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000032916", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100513634", "url": "https://www.ncbi.nlm.nih.gov/gene/100513634", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513634", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513634", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2REF7", "url": "https://www.orthodb.org/?gene=A0A5G2REF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14154", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14154", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231793", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231793", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1VWR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VWR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VWR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VWR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R834", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R834", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R834-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R834-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGALVRKAADYVRSKDFRDYLMSTHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHATNEVAQLIQGGRLIRHEMSKKASA", "length": 109, "header": "tr|A0A5G2REF7-1|A0A5G2REF7_PIG Isoform 1 of Mitochondrial pyruvate carrier OS=Sus scrofa OX=9823 GN=MPC1 PE=1 SV=1 CANONICAL=A0A5G2REF7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1VWR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7/entry#A0A4X1VWR3-1", "sequence": { "sequence": "MCEAEITSSSQSFQITDLSLLSPQRLSCLNLGDSSQNSTHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHATNEVAQLIQGGRLIRHEMSKKASA", "length": 123, "header": "tr|A0A4X1VWR3-1|A0A5G2REF7_PIG Computationally mapped isoform of Mitochondrial pyruvate carrier OS=Sus scrofa OX=9823 GN=MPC1 PE=1 SV=1 CANONICAL=A0A5G2REF7-1" }, "locus": { "chromosome": "1", "start_pos": 2552385, "end_pos": 2549085, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083136.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083136.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071295.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071295.1" } ] } }, { "isoform_ac": "A0A5G2R834-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7/entry#A0A5G2R834-1", "sequence": { "sequence": "PPRGGKEVCGARGPIRAPASRSALSHRLRDGRRAAAVRRGRAVVRGASWRVLCPRCPLRLVSLGSKERWRRHRGRRCVRHGHGGCAGAKGGGLCPEQGLPRLPHEHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHATNEVAQLIQGGRLIRHEMSKKASA", "length": 189, "header": "tr|A0A5G2R834-1|A0A5G2R834_PIG Computationally mapped isoform of Mitochondrial pyruvate carrier OS=Sus scrofa OX=9823 GN=MPC1 PE=1 SV=1 CANONICAL=A0A5G2REF7-1" }, "locus": { "chromosome": "1", "start_pos": 2552385, "end_pos": 2541385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075149.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075149.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073433.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073433.1" } ] } }, { "isoform_ac": "A0A5G2REF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7/entry#A0A5G2REF7-1", "sequence": { "sequence": "MAGALVRKAADYVRSKDFRDYLMSTHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHATNEVAQLIQGGRLIRHEMSKKASA", "length": 109, "header": "tr|A0A5G2REF7-1|A0A5G2REF7_PIG Isoform 1 of Mitochondrial pyruvate carrier OS=Sus scrofa OX=9823 GN=MPC1 PE=1 SV=1 CANONICAL=A0A5G2REF7-1" }, "locus": { "chromosome": "1", "start_pos": 2552385, "end_pos": 2541629, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091595.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091595.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073006.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073006.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VWR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VWR3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513634", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513634", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "pyruvate import into mitochondria", "id": "GO:0006850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006850", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "pyruvate transmembrane transporter activity", "id": "GO:0050833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050833", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2REF7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 109, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2REF7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2REF7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9S8-1", "uniprot_ac": "A0A5G2R9S8", "uniprot_id": "A0A5G2R9S8_PIG", "mass": { "chemical_mass": 87238.0, "monoisotopic_mass": 87238.0 }, "refseq": { "ac": "XP_003121921", "name": "phospholipase A-2-activating protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121921" }, "gene_names": [ { "name": "PLAA", "type": "recommended", "evidence": [ { "id": "A0A5G2R9S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ] }, { "name": "PLAA", "type": "synonym", "evidence": [ { "id": "XP_003121921", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121921" } ] } ], "protein_names": [ { "name": "Phospholipase A-2-activating protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R9S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8/entry#names_and_taxonomy" } ] }, { "name": "phospholipase A-2-activating protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003121921", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121921" } ] } ], "function": [ { "annotation": "Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1W6V5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W6V5#function" }, { "database": "UniProtKB", "id": "ARBA00094504", "url": "https://www.uniprot.org/uniprotkb/ARBA00094504#function" }, { "database": "UniProtKB", "id": "A0A4X1WDK2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1WDK2#function" }, { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8#function" }, { "database": "UniProtKB", "id": "F1SP81", "url": "https://www.uniprot.org/uniprotkb/F1SP81#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PLAA", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8", "locus": { "chromosome": "1", "start_pos": 196219834, "end_pos": 196176456, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005126", "url": "https://www.ensembl.org/id/ENSSSCG00000005126" } ] } } ], "crossref": [ { "id": "ENSSSCG00000005126", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005126", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100511733", "url": "https://www.ncbi.nlm.nih.gov/gene/100511733", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511733", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511733", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DKCIYYW", "url": "https://omabrowser.org/oma/group/DKCIYYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1WDK2", "url": "https://www.orthodb.org/?gene=A0A4X1WDK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R9S8", "url": "https://www.orthodb.org/?gene=A0A5G2R9S8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19849:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19849:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09070", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09070", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003121921", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121921", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1W6V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W6V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1W6V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W6V1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1W6V5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W6V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1W6V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W6V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1WDK2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1WDK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1WDK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1WDK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SP81", "url": "https://www.uniprot.org/uniprotkb/F1SP81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SP81-1", "url": "https://www.uniprot.org/uniprotkb/F1SP81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGATRYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWVPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDMYPHGLIATGGNDHNICIFSLESPAPLYVLKGHKNTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRKWQITGECLEVFYGHTNYIYSISVFPNCKDFVTTGEDRSLRIWKHGECAQTIRLPAQSIWCCCVLNNGDIVVGASDGIIRVFTESEDRTANAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGEKVEAYQWSVSERRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTQGQMLGLGNTNFSDPFTGGGRYVPGSSSGSSNTLPVADPFTGGGRYVPGSANMGTMMAGVDPFTGNSAYQSAASKTVNIYFPKKEAVTFDQANPTQILGKLKELNGTASEDKKLTEEDLVLLEKILSLICNNSSEKPTAQQLQTLWKAVNWPEDIVFPALDILRLSIKHPSVNENFCNEKEGTQFSSHLINLLNPKGKPANQLLALRTFCNCFVGKAGQKLMMSQRESLMSQAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTVLEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKFASVSEPAKVSECCRLILNLL", "length": 796, "header": "tr|A0A5G2R9S8-1|A0A5G2R9S8_PIG Isoform 1 of Phospholipase A-2-activating protein OS=Sus scrofa OX=9823 GN=PLAA PE=1 SV=2 CANONICAL=A0A5G2R9S8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1W6V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8/entry#A0A4X1W6V1-1", "sequence": { "sequence": "MASGATRYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWVPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDMYPHGLIATGGNDHNICIFSLESPAPLYVLKGHKNTGHEDCVRGLAILSETEFLSCANDASIRKWQITGECLEVFYGHTNYIYSISVFPNCKDFVTTGEDRSLRIWKHGECAQTIRLPAQSIWCCCVLNNGDIVVGASDGIIRVFTESEDRTANAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGEKVEAYQWSVSERRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTQGQMLGLGNTNFSDPFTGGGRYVPGSSSGSSNTLPVADPFTGGGRYVPGSANMGTMMAGVDPFTGNSAYQSAASKTVNIYFPKKEAVTFDQANPTQILGKLKELNGTASEDKKLTEEDLVLLEKILSLICNNSSEKPTAQQLQTLWKAVNWPEDIVFPALDILRLSIKHPSVNENFCNEKEGTQFSSHLINLLNPKGKPANQLLALRTFCNCFVGKAGQKLMMSQRESLMSQAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTVLEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKFASVSEPAKVSECCRLILNLL", "length": 722, "header": "tr|A0A4X1W6V1-1|A0A5G2R9S8_PIG Computationally mapped isoform of Phospholipase A-2-activating protein OS=Sus scrofa OX=9823 GN=PLAA PE=1 SV=1 CANONICAL=A0A5G2R9S8-1" }, "locus": { "chromosome": "1", "start_pos": 196219435, "end_pos": 196176671, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050700.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050700.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042666.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042666.1" } ] } }, { "isoform_ac": "A0A4X1W6V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8/entry#A0A4X1W6V5-1", "sequence": { "sequence": "MASGATRYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWVPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDMYPHGLIATGGNDHNICIFSLESPAPLYVLKGHKNTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRKWQITGECLEVFYGHTNYIYSISVFPNCKDFVTTGEDRSLRIWKHGECAQTIRLPAQSIWCCCVLNNGDIVVGASDGIIRVFTESEDRTANAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGEKVEAYQWSVSERRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTQGQMLGLGNTNFSDPFTGGGRYVPGSSSGSSNTLPVADPFTGGGRYVPGSANMGTMMAGVDPFTGKLKELNGTASEDKKLTEEDLVLLEKILSLICNNSSEKPTAQQLQTLWKAVNWPEDIVFPALDILRLSIKHPSVNENFCNEKEGTQFSSHLINLLNPKGKPANQLLALRTFCNCFVGKAGQKLMMSQRESLMSQAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTVLEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKFASVSEPAKVSECCRLILNLL", "length": 762, "header": "tr|A0A4X1W6V5-1|A0A5G2R9S8_PIG Computationally mapped isoform of Phospholipase A-2-activating protein OS=Sus scrofa OX=9823 GN=PLAA PE=1 SV=1 CANONICAL=A0A5G2R9S8-1" }, "locus": { "chromosome": "1", "start_pos": 196219435, "end_pos": 196176671, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040732.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040732.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057606.2", "url": "https://www.ensembl.org/id/ENSSSCP00000057606.2" } ] } }, { "isoform_ac": "A0A4X1WDK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8/entry#A0A4X1WDK2-1", "sequence": { "sequence": "MASGATRYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWVPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDMYPHGLIATGGNDHNICIFSLESPAPLYVLKGHKNTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRKWQITGECLEVFYGHTNYIYSISVFPNCKDFVTTGEDRSLRIWKHGECAQTIRLPAQSIWCCCVLNNGDIVVGASDGIIRVFTESEDRTANAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGEKVEAYQWSVSERRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTQGQMLGLGNTNFSDPFTGGGRYVPGSANMGTMMAGVDPFTGNSAYQSAASKTVNIYFPKKEAVTFDQANPTQILGKLKELNGTASEDKKLTEEDLVLLEKILSLICNNSSEKPTAQQLQTLWKAVNWPEDIVFPALDILRLSIKHPSVNENFCNEKEGTQFSSHLINLLNPKGKPANQLLALRTFCNCFVGKAGQKLMMSQRESLMSQAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTVLEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKFASVSEPAKVSECCRLILNLL", "length": 772, "header": "tr|A0A4X1WDK2-1|A0A5G2R9S8_PIG Computationally mapped isoform of Phospholipase A-2-activating protein OS=Sus scrofa OX=9823 GN=PLAA PE=1 SV=1 CANONICAL=A0A5G2R9S8-1" }, "locus": { "chromosome": "1", "start_pos": 196219435, "end_pos": 196176671, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076584.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076584.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070622.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070622.2" } ] } }, { "isoform_ac": "A0A5G2R9S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8/entry#A0A5G2R9S8-1", "sequence": { "sequence": "MASGATRYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWVPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDMYPHGLIATGGNDHNICIFSLESPAPLYVLKGHKNTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRKWQITGECLEVFYGHTNYIYSISVFPNCKDFVTTGEDRSLRIWKHGECAQTIRLPAQSIWCCCVLNNGDIVVGASDGIIRVFTESEDRTANAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGEKVEAYQWSVSERRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTQGQMLGLGNTNFSDPFTGGGRYVPGSSSGSSNTLPVADPFTGGGRYVPGSANMGTMMAGVDPFTGNSAYQSAASKTVNIYFPKKEAVTFDQANPTQILGKLKELNGTASEDKKLTEEDLVLLEKILSLICNNSSEKPTAQQLQTLWKAVNWPEDIVFPALDILRLSIKHPSVNENFCNEKEGTQFSSHLINLLNPKGKPANQLLALRTFCNCFVGKAGQKLMMSQRESLMSQAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTVLEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKFASVSEPAKVSECCRLILNLL", "length": 796, "header": "tr|A0A5G2R9S8-1|A0A5G2R9S8_PIG Isoform 1 of Phospholipase A-2-activating protein OS=Sus scrofa OX=9823 GN=PLAA PE=1 SV=2 CANONICAL=A0A5G2R9S8-1" }, "locus": { "chromosome": "1", "start_pos": 196219435, "end_pos": 196176671, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076924.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076924.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073816.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073816.2" } ] } }, { "isoform_ac": "F1SP81-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8/entry#F1SP81-1", "sequence": { "sequence": "MASGATRYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWVPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDMYPHGLIATGGNDHNICIFSLESPAPLYVLKGHKNTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRKWQITGECLEVFYGHTNYIYSISVFPNCKDFVTTGEDRSLRIWKHGECAQTIRLPAQSIWCCCVLNNGDIVVGASDGIIRVFTESEDRTANAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGEKVEAYQWSVSERRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTQGQMLGLGNTNFSDPFTGGGRYVPGSSSGSSNTLPVADPFTGGGRYVPGSANMGTMMAGVDPFTGNSAYQSAASKTVNIYFPKKEAVTFDQANPTQILDIVFPALDILRLSIKHPSVNENFCNEKEGTQFSSHLINLLNPKGKPANQLLALRTFCNCFVGKAGQKLMMSQRESLMSQAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTVLEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKFASVSEPAKVSECCRLILNLL", "length": 741, "header": "tr|F1SP81-1|A0A5G2R9S8_PIG Computationally mapped isoform of Phospholipase A-2-activating protein OS=Sus scrofa OX=9823 GN=PLAA PE=1 SV=4 CANONICAL=A0A5G2R9S8-1" }, "locus": { "chromosome": "1", "start_pos": 196219435, "end_pos": 196176671, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005651.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005651.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005510.4", "url": "https://www.ensembl.org/id/ENSSSCP00000005510.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1W6V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W6V1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511733", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511733", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1RWJ7-1", "protein_name": "Phospholipase A-2-activating protein", "gene_name": "PLAA", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGDGGVYRLRCSLLGHEQDVRGITRGLFPEGGFVSVSRDRTARLWTPDGLNRGFTEMHCMRGHSNFVSCVCIIPPSDLYPRGLIATGGNDHNICVFTVDNTAPLYVLKGHTNTVCSLSSGKFGTLLSGSWDTTCKVWLNDRCMMTLQGHTAAIWAVKILPEQGLMLTGSADKTIKLWKAGRCERTYAGHEDCVRGLAILSEMEFLSCSNDASVRRWHISGECLHVYYGHTNYIYSVSVFPHCKDFITTGEDRSLRIWKQGECVQTIRLPAQSVWCCCVLDNDDIVVGASDGIIRVFTKSLERTASAEEIQAFENELSQASIDPKTGDLGDINADDLPGKEHLKDPGMRDGQTRLIKDNGKVEAYQWSVSEGRWIKIGDVVGSSGGTQQTSGKVLFEGKEYDYVFTIDVNESGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQAPLNTNTEFSDPFTGAGRYVPGSSSLSNTAPAADPFTGAGRYVPGSASNVVAPVGGHDPYTGMGAYQSAKAENIYFPKKDAVTFDQANPTQILGKLKELNGNAAEEQKLTEDDLIILEKLLSATCNTSAEMPTAQQIQTLWKAINWPEDIVFPALDILRLSVRHPIVNENFCGEKAHVQFIHLLLKFLNPQGKPANQLLALRALCNCFVSQAGQKLLMEQRDEIMTQAIEVKSGNNKNVHIALATLTLNYAVCLHKVNNIEGKAQCLSVISTVMEVVKDLEAVFRLLVALGTLISDDKNAVQLAKSLGVDSQIKKYVSVSEPAKVKECCRFVLNLL", "length": 794 }, "evidence": [ { "id": "A0A5G2R9S8", "url": "https://omabrowser.org/oma/group/A0A5G2R9S8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F4J9W8-1", "protein_name": "Transducin family protein / WD-40 repeat family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVMDIDFNEYKLRCELHGHDDDVRGICVCNDENIATSSRDRTIRVWSLDPSDKRKYTSEKILLGHTSFVGPLAWIPPTDEYPEGRLVSGSMDTFVFVWNLMNGENIQTLKGHQMQVTGVAIDNEDIVSSSVDQTLKRWRNGQLVESWDAHQSPIQAVIRLPSGELVSGSSDASLKLWKGKTSLQTLSGHTDTVRGLAVMPDLGFLSASHDGSIRLWALSGEVLLEMVGHTSLVYSVDAHSSGLIVSASEDRHAKIWKDGVCVQSLEHPGCIWDAKFLETGDIVTACSDGVVRVWTVRHDAIADQMEIDAYDSQISQYKLSRKKVGGLKLDELPGLDSLTSPGTSDGQTKVVREGDNGVAYAWNMKEQRWDKIGEVVDGPDGVADRPIHEGVQYDFVFDVDIGDGEPIRKLPYNRSDNPYDAADKWLLKENLPFAYRQQIVEFILQNSGQKDFNFNPSFRDPFTGANAYVPGQASRTAATPAKPLYKHIPKRGVLVFDAAQYDGILKKMTEFNTTLRSDAVNNDKSLTELEVSRVGAIVNILKDTSHYHSTNFADMDIALLLKVLQAWPPAMMFPATDIVRMLVLHHHGASLLIKHVENNNDLLLDLIKKVTEDSALPANLLTTVRVLVNLFKNSSFHYWLQTHHSQILDAFSNCYSSPNKNLQLAYSTLLLNYAVLLIEKKDQEGQAQVLSAALQVPEEEAADVDSKFRSLVAIGSLMLEGLVKKIAIDFDVESIAKSAKASKEAKIAEVGADIDLVIRQ", "length": 760 }, "evidence": [ { "id": "A0A5G2R9S8", "url": "https://omabrowser.org/oma/group/A0A5G2R9S8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3HH63-1", "protein_name": "Phospholipase A-2-activating protein", "gene_name": "Plaa", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASGAARYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSEIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTESQDRTASVEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGERVEAYQWSVSDGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNVSEDPWLAAYNFLQKNDLNPMFLDQVAKFIIDNTKGQTLGLGNTSFSDPFTGGGRYVPGTSGPSNTVQAADPFTGAGRYMPGSAGMGTSMAGVDPFTGSSAYRSAASKTVNIYFPKKEALTFDQANPIQILGKLKELNGTAPEDKKLTEDDLVLLEKILSLICNNSSEKPTAQQLQILWKAINWPEDIVFPALDILRLSIKHPSVNENFCNEKEGDQFSSHLIHLLNPKGKPANQLLALRTFCNCFVSQAGQKLMMSQRESLMSQAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTILEVVQDLEATFRLLVALGTLISDDSNAIQLAKSLGVDSQIKKYASVSEPAKVSECCRLILNLL", "length": 795 }, "evidence": [ { "id": "A0A5G2R9S8", "url": "https://omabrowser.org/oma/group/A0A5G2R9S8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P27612-1", "protein_name": "Phospholipase A-2-activating protein", "gene_name": "Plaa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGASRYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFLGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYFGHTNYIYSISVFPNSKDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLENGDIVVGASDGIIRVFTESEERTASAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLSEPGTREGQTRLIRDGERVEAYQWSVSDGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNVSDDPWLVAYNFLQKNDLNPMFLDQVAKFIIDNTKGQTLGLGNTSFSDPFTGGGRYVPGTSGPSNTVQTADPFTGAGRYMPGSAGMDTTMTGVDPFTGNSAYRSAASKTVNIYFPKKEALTFDQANPTQILGKLKELNGTAPEEKKLTEDDLVLLEKILSLICNNSSEKPTAQQLQILWKAINWPEDIVFPALDILRLSIKHPNVNENFCNEKGDQFSSHLINLLNPKGKPANQLLALRTFCNCFVSQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTILEVVQDLEATFRLLVALGTLISDDSNAIQLAKSLGVDSQIKKYVSVSEPAKVSECCRLVLHLL", "length": 794 }, "evidence": [ { "id": "A0A5G2R9S8", "url": "https://omabrowser.org/oma/group/A0A5G2R9S8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P54319-1", "protein_name": "Phospholipase A-2-activating protein", "gene_name": "Plaa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGAARYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLGVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTEADERTASAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGERVEAYQWSVSDGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNVSDDPWLVAYNFLQKNDLNPMFLDQVAKFIIDNTKGQTLGLGNTSFSDPFTGGGRYVPGTSGPSNTVQTADPFTGAGRYMPGSAGMDTTMAGVDPFTGNSAYRSAASKTVNIYFPKKEALTFDQANPTQILGKLKELNGSAPEEKKLTEDDLVLLEKILSLICGNASEKPTAQQLQVLWKAINWPEDIVFPALDILRLSIKHPSVNENFCNEKEGDQFSSHLINLLNPKGKPANQLLALRTFCNCFVSQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTILEVVQDLEATFRLLVALGTLISDDSNAIQLAKSLGVDSQIKKYASVSEPAKVSECCRLILNLL", "length": 795 }, "evidence": [ { "id": "A0A5G2R9S8", "url": "https://omabrowser.org/oma/group/A0A5G2R9S8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VPY2-1", "protein_name": "Phospholipase A2 activator protein, isoform B", "gene_name": "Plap", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEPSLDNYKLSCELLGHSMDVRAVAVGPPTPEGRQTILSGSRDKSTKVWKPHGNEYLESLTLQDHKNFISYICFLESERWICTASNDATICIYKQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISEAGDVSFVALEGHEAAVWAVATLKEQRKYVTGGADRNIYYWNAKGEKLRLLKGHTDCVRGVMGLDANTLLSCGNDAVLRFWNEDGECVREMNGHSNYIYSMARNEALGDQVVVSCGEDSTLRMWNVITGDELGAPIIHPGISVWSVTCLQNGDIVTGCSDGVVRVFSHVPARQASEAVLKAFDLVVATRKSQINEEIGGVKKTDLPGPEALLSNGTREGQTKMVRHADGSVKCYTWTLGNWNLVGDVTGATGGTQSNSGKKLHEGKEYDFVFSVDISDTEPPIKLPYNRSDDPWQAAQTFIHRHSLPQAYLDQVANFIIKNSEGPVLMEQAPTGYQDPFTGGSRYVPGSSNTNMGSGGNVDPFTGASSYSTASSNAQSQVDVNFVRSGDKHFPVSNYRIFDTCDAKKVLEKMIEFNGKLSLPDGRVGEEVLLAVIKLADQSPELDLTSLEALAILLKWPASMQFPVLDILRLAVRNEAIFSVLNNSHNFLATVIPQLSGSAPNQLMVVRCLANIMSHAAGRQNVMSRLAEIIDLVGAIKTGSANLQIAVATFYLNLTISQTLDVAKSEVCHVVTSGIVELLKWAKDLEACYRSMQAIGNLTTTSCGQETIAQVVSVDYVMDKLRELTITPQDKNFSKVNSVGQALLAVF", "length": 787 }, "evidence": [ { "id": "A0A5G2R9S8", "url": "https://omabrowser.org/oma/group/A0A5G2R9S8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y263-1", "protein_name": "Phospholipase A-2-activating protein", "gene_name": "PLAA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLWAPDSPNRSFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTESEDRTASAEEIKAFEKELSHATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGEKVEAYQWSVSEGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNTSDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQMLGLGNPSFSDPFTGGGRYVPGSSGSSNTLPTADPFTGAGRYVPGSASMGTTMAGVDPFTGNSAYRSAASKTMNIYFPKKEAVTFDQANPTQILGKLKELNGTAPEEKKLTEDDLILLEKILSLICNSSSEKPTVQQLQILWKAINCPEDIVFPALDILRLSIKHPSVNENFCNEKEGAQFSSHLINLLNPKGKPANQLLALRTFCNCFVGQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLALNYSVCFHKDHNIEGKAQCLSLISTILEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKYSSVSEPAKVSECCRFILNLL", "length": 795 }, "evidence": [ { "id": "A0A5G2R9S8", "url": "https://omabrowser.org/oma/group/A0A5G2R9S8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "cytoplasmic ubiquitin ligase complex", "id": "GO:0000153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000153", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "positive regulation of dendrite extension", "id": "GO:1903861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903861", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "ubiquitin recycling", "id": "GO:0010992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010992", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "positive regulation of prostaglandin biosynthetic process", "id": "GO:0031394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031394", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "positive regulation of synaptic vesicle recycling", "id": "GO:1903423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903423", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "negative regulation of protein K63-linked ubiquitination", "id": "GO:1900045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900045", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "positive regulation of neuron migration", "id": "GO:2001224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001224", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phospholipase A2 activator activity", "id": "GO:0016005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016005", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9S8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" }, { "id": "PS51394", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51394" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PFU", "eco_id": "ECO_0000259", "start_pos": 366, "end_pos": 465, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R9S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9S8" }, { "id": "PS51396", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51396" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PUL", "eco_id": "ECO_0000259", "start_pos": 534, "end_pos": 795, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 421, "end_pos": 423 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 560, "end_pos": 562 }, { "start_pos": 586, "end_pos": 588 }, { "start_pos": 587, "end_pos": 589 }, { "start_pos": 709, "end_pos": 711 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAY1-1", "uniprot_ac": "A0A5G2RAY1", "uniprot_id": "A0A5G2RAY1_PIG", "mass": { "chemical_mass": 77984.0, "monoisotopic_mass": 77984.0 }, "refseq": {}, "gene_names": [ { "name": "INHCA", "type": "recommended", "evidence": [ { "id": "A0A5G2RAY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1" } ] } ], "protein_names": [ { "name": "Inhibitor of carbonic anhydrase", "type": "synonym", "evidence": [ { "id": "A0A5G2RAY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "INHCA", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1", "locus": {} } ], "crossref": [ { "id": "A0A5G2RAY1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000028203", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000028203", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13617", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13617", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13618", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13618", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RVQWCAV", "url": "https://omabrowser.org/oma/group/RVQWCAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11485", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11485", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11485:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11485:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00405", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00405", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QBE8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QBE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLB1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LBF1", "url": "https://www.uniprot.org/uniprotkb/I3LBF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LBF1-1", "url": "https://www.uniprot.org/uniprotkb/I3LBF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTSMNVISLERDPAHAGLCLAFPKETVRWCTVSSQEASKCSSFRHNMKKILPVEGPHVSCVKRTSYLECIRAILANEADAVTIDGGLVFEAGLAPYNLKPVVAEFYGSKDDPQTHYYAVAVVKKGSDFQLSQLRGKKSCHTGLGWSAGWNIPMGILLPPDSGEEAAAKFFSSSCVPCADRMAFPKMCQLCAGKGVEKCACSNHERYFGYSGAFKCLQEDVGDVAFVRHVTVFENLPDKADRDQYELLCKDNTRRPVDDYENCYLAQVPSHAVVARSVDGKEDLIWELLNQAQENFGKDKSAEFQLFSSSHGKDLLFTDACLGFLRVPPKMDAKLYLGYEYFAAIQHLRRVQGTEEPQRVMWCAVGQHERTKCDSWSVLSGGILNCNSEDTMEDCIAAIAKGEADAMSLDGGFLYTAGKCGLVPVLAENYLSQDGKERFGSKCVNTPVEGYYVVAVVKKSDADLTWNSLRGKKSCHTAVGTSAGWIIPMGFIYNQTGSCKLDEFFSQSCAPGSDPESRLCALCSGSISGQPAHTCAPNSHEGYHGFSGALRCLVEKGDVAFVKHPTVLQNTDGRNPEAWAKDLKQEDFQLLCPDGTRKPVTEAQSCHLAAVPSHAVVSRKDKADFVRRMLFNQQELFGRNGFEYMMFQLFKSSTEDLLFSDDTECLANLQDKITYQKYLGPEYLQAIANVRQCFPSELLDACTFHGN", "length": 707, "header": "tr|A0A5G2RAY1-1|A0A5G2RAY1_PIG Isoform 1 of Inhibitor of carbonic anhydrase OS=Sus scrofa OX=9823 GN=INHCA PE=3 SV=1 CANONICAL=A0A5G2RAY1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QBE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1/entry#A0A5G2QBE8-1", "sequence": { "sequence": "MRLAFCVLLCAGSLGLCLAFPKETVRWCTVSSQEASKCSSFRHNMKKILPVEGPHVSCVKRTSYLECIRAILANEADAVTIDGGLVFEAGLAPYNLKPVVAEFYGSKDDPQTHYYAVAVVKKGSDFQLSQLRGKKSCHTGLGWSAGWNIPMGILLPPDSGEEAAAKFFSSSCVPCADRMAFPKMCQLCAGKGVEKCACSNHERYFGYSGAFKCLQEDVGDVAFVRHVTVFENLPDKADRDQYELLCKDNTRRPVDDYENCYLAQVPSHAVVARSVDGKEDLIWELLNQAQENFGKDKSAEFQLFSSSHGKDLLFTDACLGFLRVPPKMDAKLYLGYEYFAAIQHLRRVQGTEEPQRVMWCAVGQHERTKCDSWSVLSGGILNCNSEDTMEDCIAAIAKGEADAMSLDGGFLYTAGKCGLVPVLAENYLSQDGKERFGSKCVNTPVEGYYVVAVVKKSDADLTWNSLRGKKSCHTAVGTSAGWIIPMGFIYNQTGSCKLDEFFSQSCAPGSDPESRLCALCSGSISGQPAHTCAPNSHEGYHGFSGALRCLVEKGDVAFVKHPTVLQNTDGRNPEAWAKDLKQEDFQLLCPDGTRKPVTEAQSCHLAAVPSHAVVSRKDKADFVRRMLFNQQNFWMPALSMEIKN", "length": 644, "header": "tr|A0A5G2QBE8-1|A0A5G2RAY1_PIG Computationally mapped isoform of Inhibitor of carbonic anhydrase OS=Sus scrofa OX=9823 GN=INHCA PE=3 SV=2 CANONICAL=A0A5G2RAY1-1" }, "locus": { "chromosome": "13", "start_pos": 74906889, "end_pos": 74862604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085661.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085661.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061379.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061379.2" } ] } }, { "isoform_ac": "A0A5G2RAY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1/entry#A0A5G2RAY1-1", "sequence": { "sequence": "MSTSMNVISLERDPAHAGLCLAFPKETVRWCTVSSQEASKCSSFRHNMKKILPVEGPHVSCVKRTSYLECIRAILANEADAVTIDGGLVFEAGLAPYNLKPVVAEFYGSKDDPQTHYYAVAVVKKGSDFQLSQLRGKKSCHTGLGWSAGWNIPMGILLPPDSGEEAAAKFFSSSCVPCADRMAFPKMCQLCAGKGVEKCACSNHERYFGYSGAFKCLQEDVGDVAFVRHVTVFENLPDKADRDQYELLCKDNTRRPVDDYENCYLAQVPSHAVVARSVDGKEDLIWELLNQAQENFGKDKSAEFQLFSSSHGKDLLFTDACLGFLRVPPKMDAKLYLGYEYFAAIQHLRRVQGTEEPQRVMWCAVGQHERTKCDSWSVLSGGILNCNSEDTMEDCIAAIAKGEADAMSLDGGFLYTAGKCGLVPVLAENYLSQDGKERFGSKCVNTPVEGYYVVAVVKKSDADLTWNSLRGKKSCHTAVGTSAGWIIPMGFIYNQTGSCKLDEFFSQSCAPGSDPESRLCALCSGSISGQPAHTCAPNSHEGYHGFSGALRCLVEKGDVAFVKHPTVLQNTDGRNPEAWAKDLKQEDFQLLCPDGTRKPVTEAQSCHLAAVPSHAVVSRKDKADFVRRMLFNQQELFGRNGFEYMMFQLFKSSTEDLLFSDDTECLANLQDKITYQKYLGPEYLQAIANVRQCFPSELLDACTFHGN", "length": 707, "header": "tr|A0A5G2RAY1-1|A0A5G2RAY1_PIG Isoform 1 of Inhibitor of carbonic anhydrase OS=Sus scrofa OX=9823 GN=INHCA PE=3 SV=1 CANONICAL=A0A5G2RAY1-1" }, "locus": { "chromosome": "13", "start_pos": 74906882, "end_pos": 74863002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075648.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075648.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067763.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067763.1" } ] } }, { "isoform_ac": "A0A5G2RLB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1/entry#A0A5G2RLB1-1", "sequence": { "sequence": "WNRVMCGLLWLCLAFPKETVRWCTVSSQEASKCSSFRHNMKKILPVEGPHVSCVKRTSYLECIRAILANEADAVTIDGGLVFEAGLAPYNLKPVVAEFYGSKDDPQTHYYAVAVVKKGSDFQLSQLRGKKSCHTGLGWSAGWNIPMGILLPPDSGEEAAAKFFSSSCVPCADRMAFPKMCQLCAGKGVEKCACSNHERYFGYSGAFKCLQEDVGDVAFVRHVTVFENLPDKADRDQYELLCKDNTRRPVDDYENCYLAQVPSHAVVARSVDGKEDLIWELLNQAQENFGKDKSAEFQLFSSSHGKDLLFTDACLGFLRVPPKMDAKLYLGYEYFAAIQHLRRVQGTEEPQRVMWCAVGQHERTKCDSWSVLSGGILNCNSEDTMEDCIAAIAKGEADAMSLDGGFLYTAGKCGLVPVLAENYLSQDGKERFGSKCVNTPVEGYYVVAVVKKSDADLTWNSLRGKKSCHTAVGTSAGWIIPMGFIYNQTGSCKLDEFFSQSCAPGSDPESRLCALCSGSISGQPAHTCAPNSHEGYHGFSGALRCLVEKGDVAFVKHPTVLQNTDGRNPEAWAKDLKQEDFQLLCPDGTRKPVTEAQSCHLAAVPSHAVVSRKDKADFVRRMLFNQQELFGRNGFEYMMFQLFKSSTEDLLFSDDTECLANLQDKITYQKYLGPEYLQAIANVRQCFPSGE", "length": 690, "header": "tr|A0A5G2RLB1-1|A0A5G2RAY1_PIG Computationally mapped isoform of Inhibitor of carbonic anhydrase OS=Sus scrofa OX=9823 GN=INHCA PE=3 SV=1 CANONICAL=A0A5G2RAY1-1" }, "locus": { "chromosome": "13", "start_pos": 74905749, "end_pos": 74872975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081266.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081266.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073058.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073058.1" } ] } }, { "isoform_ac": "I3LBF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1/entry#I3LBF1-1", "sequence": { "sequence": "MRLAFCVLLCAGSLGLCLAFPKETVRWCTVSSQEASKCSSFRHNMKKILPVEGPHVSCVKRTSYLECIRAILANEADAVTIDGGLVFEAGLAPYNLKPVVAEFYGSKDDPQTHYYAVAVVKKGSDFQLSQLRGKKSCHTGLGWSAGWNIPMGILLPPDSGEEAAAKFFSSSCVPCADRMAFPKMCQLCAGKGVEKCACSNHERYFGYSGAFKCLQEDVGDVAFVRHVTVFENLPDKADRDQYELLCKDNTRRPVDDYENCYLAQVPSHAVVARSVDGKEDLIWELLNQAQENFGKDKSAEFQLFSSSHGKDLLFTDACLGFLRVPPKMDAKLYLGYEYFAAIQHLRRVQGTEEPQRVMWCAVGQHERTKCDSWSVLSGGILNCNSEDTMEDCIAAIAKGEADAMSLDGGFLYTAGKCGLVPVLAENYLSQDGKERFGSKCVNTPVEGYYVVAVVKKSDADLTWNSLRGKKSCHTAVGTSAGWIIPMGFIYNQTGSCKLDEFFSQSCAPGSDPESRLCALCSGSISGQPAHTCAPNSHEGYHGFSGALRCLVEKGDVAFVKHPTVLQNTDGRNPEAWAKDLKQEDFQLLCPDGTRKPVTEAQSCHLAAVPSHAVVSRKDKADFVRRMLFNQQELFGRNGFEYMMFQLFKSSTEDLLFSDDTECLANLQDKITYQKYLGPEYLQAIANVRQCFPSELLDACTFHGN", "length": 704, "header": "tr|I3LBF1-1|A0A5G2RAY1_PIG Computationally mapped isoform of Inhibitor of carbonic anhydrase OS=Sus scrofa OX=9823 GN=INHCA PE=3 SV=2 CANONICAL=A0A5G2RAY1-1" }, "locus": { "chromosome": "13", "start_pos": 74906882, "end_pos": 74862604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027958.4", "url": "https://www.ensembl.org/id/ENSSSCT00000027958.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021371.2", "url": "https://www.ensembl.org/id/ENSSSCP00000021371.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QBE8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBE8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LK24-1", "protein_name": "Inhibitor of carbonic anhydrase", "gene_name": "LOC100761626", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRLVVCALLCAGTLGLCLAAPKRTIRWCVVSDQEATKCSSFSDNMKKVLPADGPSVSCVMKTSYPECIKDISANKADAVTVDAALVAEAGLPHYSLKPIMAEYYGSKDDPKTHYYAVALVKKGTGFQLNQLRGKKSCHAGLGWSAGWYTPLSILLPPGSLETAAATFFSSSCVPCADGKTFPSLCQLCAGKGMDKCACSSSEPYFGYSGALKCLQDGAGDVSFVRHLAVFEVLPHKADRDQYELLCTDNTRRPVDEYEQCYLARVPSHVVLARSVDGKEDLIQELLRVAQEHFGNGKSSAFQLFGSPHGKDLLFTDTAHGLLRVPPKMDINLYLGYEHFSNIKNLKRGLEDSRRVQWCAVGQQERAKCDHWSAVSGGALACVTKETPEDCIAAITKGEADAMSLDGGFAYIAGHCGLVPVLGENYMSPHGSERLGSMCVNAPLEGYYVVAVVKKSDVGITWNSLRGKKSCHTAVGTSAGWTIPLGLIYNQTGSCKFDEFFSRSCAPGSNPDSSLCALCAGGDNPAHMCAANSQEGYHGSSGALRCLVEKGDVAFMKHPTVLQNTDGKNLESWAKGLRQEDFELLCLDGTRKPVTEAQSCHLARVPNHAVFSRKDKVYFTRRILFNQQELFARNGFEKMMFQMFGSSAKDLLFSDDTECLSNLQNKTTYKTYLGPQYLTVMDNFRQCLSSELLDACTFHRH", "length": 700 }, "evidence": [ { "id": "A0A5G2RAY1", "url": "https://omabrowser.org/oma/group/A0A5G2RAY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LXQ3-1", "protein_name": "Inhibitor of carbonic anhydrase", "gene_name": "Inhca", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLCMRRFRLGGTHGSWPGPAGCRTDQQKSRTCRSGARGPAANSPHCAGQCTRKYSKKLIAACIWKNDKAEVTQPCGPGCSWENKKFCICARAVPEPGLTQLGQHYCSPVNTVSLPGSHIRNRLCLAVPEKTIRWCIVSDHEATKCSSFRDNMKKVLPAGGPAVACVRKTSHLECIRDISANKIDAVTVDGALVAEADLPHHSLKPIMAEYYGSKDDPQTHYYVVAVVKKGTGFQLNQLQGKKSCHASLGWSAGWYVPLSVLLPSGSRETAAATFFSSSCVPCADGKMFPRLCQLCSGKGTDKCSCSSGEPYFGYWGALKCLQDGTGDVSFVRHLTVFEVMPRKADRDQYELLCPDNTRRPVDEYEQCYLARVPSHVVVARSVDGKEDSIQELLRVAQEHFGKDKSSTFQLFGSPHGKDLLFTDAACGLLRVPPKMDIGLYLGYELLSAIRNLKRGSEDSRRVKWCAVGQQERAKCDHWSAVSGGALACATEETPEDCIAAVMKGEADAVNLDGGFAYIAGHCGLVPGLGENYLSPHSSERLGSKCVNAALEGYYVVAVVKKSDVGITWNSLQGKKSCHTAVGTSAGWNVPMSLIYNQTGSCKFDEFFSGGCAPGANPDSRLCALCAGGNEPAHMCAANNDEGYHGSSGALRCLVEKGDVAFMKHPTVLQNTDGKNPESWAKGLKHEDFELLCLDGTRKPVTEAQNCHLDRVPNHAVFSRKDKVDFVQRMLFNQQELFGRNGFEYRMFQMFESSHKDLLFSDDTECLSNLQNKATYKTYLGPQYLTLMDNFRQCLSSELLDACTFHKH", "length": 808 }, "evidence": [ { "id": "A0A5G2RAY1", "url": "https://omabrowser.org/oma/group/A0A5G2RAY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DBD0-1", "protein_name": "Inhibitor of carbonic anhydrase", "gene_name": "Inhca", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLLICALLCLGTLGLCLALPEKTIRWCVVSDHEATKCSSFRDNMKKVLPAGGPAVTCVRKMSHPECIRDISANKVDAVTVDGALVAEADLPHHSLKPIMAEYYGSKDDPKTHYYVVAMAKKGTGFQLNQLRGKKSCHTGLGWSAGWYVPLSTLLPSGSRETAAATFFSSSCVPCADGKMFPSLCQLCAGKGTDKCACSSREPYFGSWGALKCLQDGTADVSFVKHLTVFEAMPTKADRDQYELLCMDNTRRPVEEYEQCYLARVPSHVVVARSVDGKEDSIQELLRVAQEHFGKDKSSPFQLFGSPHGEDLLFTDAAHGLLRVPRKIDISLYLGYEFLSAFRNLKRGLEDSQRVKWCAVGQQERTKCDQWSAVSGGALACATEETPEDCIAATMKGEADAMSLDGGFAYVAGHCGLVPVLAENYLSTHSSGRLGSKCVNAPLEGYYVVAVVKKSDVGITWKSLQGKKSCHTAVGTSEGWNVPMGLIYNQTGSCKFDAFFSRSCAPGSDPDSPLCALCVGGNNPAHMCAANNAEGYHGSSGALRCLVEKGDVAFMKHPTVLQNTDGKNPEPWAKGLKHEDFELLCLDGTRKPVTEAQSCHLARVPNRAVFSRKDKADFVRRILFNQQELFGRNGFEYMMFQMFESSAKDLLFSDDTECLSNLQNKTTYKTYLGPQYLTLMDNFRQCLSSELLDACTFHKY", "length": 700 }, "evidence": [ { "id": "A0A5G2RAY1", "url": "https://omabrowser.org/oma/group/A0A5G2RAY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1" } ], "pmid": "" }, { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of multicellular organismal process", "id": "GO:0051241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051241", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1" } ], "pmid": "" }, { "name": "antibacterial humoral response", "id": "GO:0019731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019731", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAY1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 707, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAY1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAY1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAY1" }, { "id": "PS51408", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51408" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transferrin-like", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 350, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 494, "end_pos": 496 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9R9-1", "uniprot_ac": "A0A5G2R9R9", "uniprot_id": "A0A5G2R9R9_PIG", "mass": { "chemical_mass": 63867.0, "monoisotopic_mass": 63867.0 }, "refseq": {}, "gene_names": [ { "name": "SEPTIN9", "type": "recommended", "evidence": [ { "id": "A0A5G2R9R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ] } ], "protein_names": [ { "name": "Septin 9", "type": "synonym", "evidence": [ { "id": "A0A5G2R9R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SEPTIN9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9", "locus": { "chromosome": "12", "start_pos": 4254775, "end_pos": 4405628, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017168", "url": "https://www.ensembl.org/id/ENSSSCG00000017168" } ] } } ], "crossref": [ { "id": "A0A5G2R9R9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9R9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017168", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017168", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01850", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01850", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR016491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR18884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QDY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QDY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMI6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRA0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FF69", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FF69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI77", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ71", "url": "https://www.uniprot.org/uniprotkb/F1RZ71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ71-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKSYSGVTRTSSGRLRKLGDPTGPALKRSFEVEEVETPNSTPPRRVQPPLLRATVASSTQKFQDLGVKNSEPTARHVDSLSQRSPKAALRRVELAGPKAEPVSRRTEISIDISSKQVENAGPTGPSRFGLKRAEVLGHKTPEPTPRRTEISIAKPQEAAHRRVETPSSKTPEAPAAPAADAAPKRVEIQVPKPAEAPASPIPQTLENSEPTPMSQLQSRLEPKPQPPVAEAPPRSQEASEVAPGSTGDMADTPRDAGLKQAPAPRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPPSEERIPIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHALRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTSHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLHESSGAVANGVEEKAPEAQEM", "length": 573, "header": "tr|A0A5G2R9R9-1|A0A5G2R9R9_PIG Isoform 1 of Septin 9 OS=Sus scrofa OX=9823 GN=SEPTIN9 PE=1 SV=1 CANONICAL=A0A5G2R9R9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QDY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9/entry#A0A5G2QDY0-1", "sequence": { "sequence": "TRRSFEVEEVETPNSTPPRRVQPPLLRATVASSTQKFQDLGVKNSEPTARHVDSLSQRSPKAALRRVELAGPKAEPVSRRTEISIDISSKQVENAGPTGPSRFGLKRAEVLGHKTPEPTPRRTEISIAKPQEAAHRRVETPSSKTPEAPAAPAADAAPKRVEIQVPKPAEAPSPHLRMWGLSRHLPGTPATPNAPSPLSAASEVAPGSTGDMADTPRDAGLKQAPAPRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPPSEEHIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHALRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTSHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLHESSGAVANGVEEKAPEAQEM", "length": 533, "header": "tr|A0A5G2QDY0-1|A0A5G2R9R9_PIG Computationally mapped isoform of Septin 9 OS=Sus scrofa OX=9823 GN=SEPTIN9 PE=1 SV=2 CANONICAL=A0A5G2R9R9-1" }, "locus": { "chromosome": "12", "start_pos": 4324301, "end_pos": 4256434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066597.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066597.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062358.2", "url": "https://www.ensembl.org/id/ENSSSCP00000062358.2" } ] } }, { "isoform_ac": "A0A5G2QMI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9/entry#A0A5G2QMI6-1", "sequence": { "sequence": "MRKSYSALKRSFEVEEVETPNSTPPRRVQPPLLRATVASSTQKFQDLGVKNSEPTARHVDSLSQRSPKAALRRVELAGPKAEPVSRRTEISIDISSKQVENAGPTGPSRFGLKRAEVLGHKTPEPTPRRTEISIAKPQEAAHRRVETPSSKTPEAPAAPAADAAPKRVEIQVPKPAEAPASPIPQTLENSEPTPMSQLQSRLEPKPQPPVAEAPPRSQEASEVAPGSTGDMADTPRDAGLKQAPAPRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPPSEERIPIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHALRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTSHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLHESSGAVANGVEEKAPEAQEM", "length": 554, "header": "tr|A0A5G2QMI6-1|A0A5G2R9R9_PIG Computationally mapped isoform of Septin 9 OS=Sus scrofa OX=9823 GN=SEPTIN9 PE=1 SV=1 CANONICAL=A0A5G2R9R9-1" }, "locus": { "chromosome": "12", "start_pos": 4405592, "end_pos": 4256434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070206.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070206.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066087.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066087.1" } ] } }, { "isoform_ac": "A0A5G2QRA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9/entry#A0A5G2QRA0-1", "sequence": { "sequence": "MSDPAVNAQLDGIISDFEALKRSFEVEEVETPNSTPPRRVQPPLLRATVASSTQKFQDLGVKNSEPTARHVDSLSQRSPKAALRRVELAGPKAEPVSRRTEISIDISSKQVENAGPTGPSRFGLKRAEVLGHKTPEPTPRRTEISIAKPQEAAHRRVETPSSKTPEAPAAPAADAAPKRVEIQVPKPAEAPASPIPQTLENSEPTPMSQLQSRLEPKPQPPVAEAPPRSQEASEVAPGSTGDMADTPRDAGLKQAPAPRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPPSEERIPIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHALRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTSHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLHESSGAVANGVEEKAPEAQEM", "length": 566, "header": "tr|A0A5G2QRA0-1|A0A5G2R9R9_PIG Computationally mapped isoform of Septin 9 OS=Sus scrofa OX=9823 GN=SEPTIN9 PE=1 SV=1 CANONICAL=A0A5G2R9R9-1" }, "locus": { "chromosome": "12", "start_pos": 4347466, "end_pos": 4256434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072395.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072395.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064571.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064571.1" } ] } }, { "isoform_ac": "A0A5G2R9R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9/entry#A0A5G2R9R9-1", "sequence": { "sequence": "MRKSYSGVTRTSSGRLRKLGDPTGPALKRSFEVEEVETPNSTPPRRVQPPLLRATVASSTQKFQDLGVKNSEPTARHVDSLSQRSPKAALRRVELAGPKAEPVSRRTEISIDISSKQVENAGPTGPSRFGLKRAEVLGHKTPEPTPRRTEISIAKPQEAAHRRVETPSSKTPEAPAAPAADAAPKRVEIQVPKPAEAPASPIPQTLENSEPTPMSQLQSRLEPKPQPPVAEAPPRSQEASEVAPGSTGDMADTPRDAGLKQAPAPRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPPSEERIPIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHALRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTSHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLHESSGAVANGVEEKAPEAQEM", "length": 573, "header": "tr|A0A5G2R9R9-1|A0A5G2R9R9_PIG Isoform 1 of Septin 9 OS=Sus scrofa OX=9823 GN=SEPTIN9 PE=1 SV=1 CANONICAL=A0A5G2R9R9-1" }, "locus": { "chromosome": "12", "start_pos": 4405592, "end_pos": 4256434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073544.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073544.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070879.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070879.1" } ] } }, { "isoform_ac": "A0A8W4FF69-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9/entry#A0A8W4FF69-1", "sequence": { "sequence": "QERNRRLPLKRSFEVEEVETPNSTPPRRVQPPLLRATVASSTQKFQDLGVKNSEPTARHVDSLSQRSPKAALRRVELAGPKAEPVSRRTEISIDISSKQVENAGPTGPSRFGLKRAEVLGHKTPEPTPRRTEISIAKPQEAAHRRVETPSSKTPEAPAAPAADAAPKRVEIQVPKPAEAPSPHLRMWGLSRHLPGTPATPNAPSPLSAASEVAPGSTGDMADTPRDAGLKQAPAPRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPPSEEHIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHALRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTSHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLHESSGAVANGVEEKAPEAQEM", "length": 541, "header": "tr|A0A8W4FF69-1|A0A5G2R9R9_PIG Computationally mapped isoform of Septin 9 OS=Sus scrofa OX=9823 GN=SEPTIN9 PE=1 SV=1 CANONICAL=A0A5G2R9R9-1" }, "locus": { "chromosome": "12", "start_pos": 4324380, "end_pos": 4256434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092084.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092084.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077512.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077512.1" } ] } }, { "isoform_ac": "A0A8W4FI77-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9/entry#A0A8W4FI77-1", "sequence": { "sequence": "PPGYLGWAGWRLASEVAPGSTGDMADTPRDAGLKQAPAPRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPPSEEHIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHALRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEGEPPSRRWGRSHRGGCPLVPTRWEGNKGAVGWSGTTASS", "length": 322, "header": "tr|A0A8W4FI77-1|A0A5G2R9R9_PIG Computationally mapped isoform of Septin 9 OS=Sus scrofa OX=9823 GN=SEPTIN9 PE=1 SV=1 CANONICAL=A0A5G2R9R9-1" }, "locus": { "chromosome": "12", "start_pos": 4267264, "end_pos": 4260488, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095120.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095120.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078018.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078018.1" } ] } }, { "isoform_ac": "A0A8W4FMC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9/entry#A0A8W4FMC5-1", "sequence": { "sequence": "TSPGLAGVTRPRTGSSRPALKRSFEVEEVETPNSTPPRRVQPPLLRATVASSTQKFQDLGVKNSEPTARHVDSLSQRSPKAALRRVELAGPKAEPVSRRTEISIDISSKQVENAGPTGPSRFGLKRAEVLGHKTPEPTPRRTEISIAKPQEAAHRRVETPSSKTPEAPAAPAADAAPKRVEIQVPKPAEAPSPHLRMWGLSRHLPGTPATPNAPSPLSAASEVAPGSTGDMADTPRDAGLKQAPAPRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPPSEEHIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHALRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTSHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLHESSGAVANGVEEKAPEAQEM", "length": 552, "header": "tr|A0A8W4FMC5-1|A0A5G2R9R9_PIG Computationally mapped isoform of Septin 9 OS=Sus scrofa OX=9823 GN=SEPTIN9 PE=1 SV=1 CANONICAL=A0A5G2R9R9-1" }, "locus": { "chromosome": "12", "start_pos": 4324865, "end_pos": 4256434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092042.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092042.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080645.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080645.1" } ] } }, { "isoform_ac": "F1RZ71-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9/entry#F1RZ71-1", "sequence": { "sequence": "MERDRITALKRSFEVEEVETPNSTPPRRVQPPLLRATVASSTQKFQDLGVKNSEPTARHVDSLSQRSPKAALRRVELAGPKAEPVSRRTEISIDISSKQVENAGPTGPSRFGLKRAEVLGHKTPEPTPRRTEISIAKPQEAAHRRVETPSSKTPEAPAAPAADAAPKRVEIQVPKPAEAPASPIPQTLENSEPTPMSQLQSRLEPKPQPPVAEAPPRSQEASEVAPGSTGDMADTPRDAGLKQAPAPRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPPSEERIPIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHALRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTSHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLHESSGAVANGVEEKAPEAQEM", "length": 555, "header": "tr|F1RZ71-1|A0A5G2R9R9_PIG Computationally mapped isoform of Septin 9 OS=Sus scrofa OX=9823 GN=SEPTIN9 PE=1 SV=4 CANONICAL=A0A5G2R9R9-1" }, "locus": { "chromosome": "12", "start_pos": 4379545, "end_pos": 4256434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018692.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018692.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018191.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018191.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 124, "start_aa": "Thr", "end_pos": 124, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr124", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 145, "start_aa": "Thr", "end_pos": 145, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr145", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QDY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDY0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "septin ring", "id": "GO:0005940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005940", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "non-motile cilium", "id": "GO:0097730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "septin complex", "id": "GO:0031105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031105", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" }, { "name": "positive regulation of non-motile cilium assembly", "id": "GO:1902857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902857", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9R9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 573, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9R9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9R9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9R9" }, { "id": "PS51719", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51719" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Septin-type G", "eco_id": "ECO_0000259", "start_pos": 293, "end_pos": 554, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 124, 145 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 40, "end_pos": 42 }, { "start_pos": 514, "end_pos": 516 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R986-1", "uniprot_ac": "A0A5G2R986", "uniprot_id": "A0A5G2R986_PIG", "mass": { "chemical_mass": 193728.0, "monoisotopic_mass": 193728.0 }, "refseq": {}, "gene_names": [ { "name": "TNS1", "type": "recommended", "evidence": [ { "id": "A0A5G2R986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986" } ] } ], "protein_names": [ { "name": "Tensin 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R986", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TNS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986", "locus": { "chromosome": "15", "start_pos": 119951091, "end_pos": 120164713, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027669", "url": "https://www.ensembl.org/id/ENSSSCG00000027669" } ] } } ], "crossref": [ { "id": "ENSSSCG00000027669", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027669", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01213", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01213", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09927", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09927", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45734", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45734", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45734:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45734:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QMY3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNI3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R986", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R986-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRLSWCFSCVIRWSKYLFSCFLPLRFCLRRQPEDLEAPKTHHFKVKTFKKVKPCGICRQVITREGCTCKEGAFRGGNTRKNLEEDVSMRRGRRKIPLSACCLPRNMSVSRSTEDSCELDLVYVTERIIAVSFPSTANEDNFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITRLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNVQGDSQTSICITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFNGHRDDGMEEVVGHTQGPLDGSLYAKVKKKDSLNGSTSAVNATRPVLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPAPGPSSAQAALSPEEKRELDRLLSGFGLEREKQGSMYHTQHLRSRPGEGPAAPSSGRHIIPAQVHVNGGALASERETDILDDELPNQDGHSVGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKPYSVEPMVNGGGYPYESASRVVPAQAGHMAPMRPSYSAQEGLAGHQREGPHPGWSQSMTTSHYGHDPSGMFRSQSFPESEPQLPPAPARGGSSREAVQRGLNCWQQQQQQQQQQQPRPPPRQQERAHLESLGLSRPSPQPLAEPPMPGLPEFPRAASQQEIEQSIETLNMLMLDLEPAAAAAAPLHKSQSVPGAWPGASPLSSQPLSGSSYQSHPLTQSRSGYIPSGNSLATPEPIPRASLESVPSGRSYSPYDYQPCPSGPNQSYRPKSPSSSGPQQPPASLPGLTAQPRLPPKEMTPDPSRTPEEEPLNLGGVQAREKQPAEPPAPLRRRAASDGQYENQSPEPTSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPTSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGEPRSYVESVVRTAVAGPRTQDAEPKSFSAPAAQAYGHETPLRNGTLGGSFVSPSPLSTSSPILSADGTSVGSFPSGENGDPGPRTPTQPLLDSGFRATGSLGQPSPSAQRSYQSSSPIPAAGSSYHSPDYALQQFGSPESQARSQFSVAGVHAVPGSPQARHRTVGTNTPPSPGFGRRAVNPSMAAPSSPSLSHRQVMGPPGPGFHGNAVSSPQSSAATTPGSPSLGRHPGAHQVSSLHGNVATTPGSPSLGRHPGAHQGNLASSLHGNAIPSPGSPSLGRHLGGSGSVVPGSPSLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSMGDRAGSLPNYATVNGKVSSSPVPSGMSSPSGGSTVSFSHTLPDFSKCSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGPANSTSDLLKQGAACNVLFLNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQDRKWVKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLSAGQKR", "length": 1802, "header": "tr|A0A5G2R986-1|A0A5G2R986_PIG Isoform 1 of Tensin 1 OS=Sus scrofa OX=9823 GN=TNS1 PE=1 SV=2 CANONICAL=A0A5G2R986-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QMY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986/entry#A0A5G2QMY3-1", "sequence": { "sequence": "MLIALLALPFLPGVQAREKQPAEPPAPLRRRAASDGQYENQSPEPTSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPTSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGEPRSYVESVVRTAVAGPRTQDAEPKSFSAPAAQAYGHETPLRNGTLGGSFVSPSPLSTSSPILSADGTSVGSFPSGENGDPGPRTPTQPLLDSGFRATGSLGQPSPSAQRSYQSSSPIPAAGSSYHSPDYALQQFGSPESQARSQFSVAGVHAVPGSPQARHRTVGTNTPPSPGFGRRAVNPSMAAPSSPSLSHRQVMGPPGPGFHGNAVSSPQSSAATTPGSPSLGRHPGAHQVSSLHGNVATTPGSPSLGRHPGAHQGNLASSLHGNAIPSPGSPSLGRHLGGSGSVVPGSPSLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSMGDRAGSLPNYATVNGKVSSSPVPSGMSSPSGGSTVSFSHTLPDFSKCSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGPANSTSDLLKQGAACNVLFLNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFFSCRHLLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLSAGQKR", "length": 835, "header": "tr|A0A5G2QMY3-1|A0A5G2QMY3_PIG Computationally mapped isoform of Tensin 1 OS=Sus scrofa OX=9823 GN=TNS1 PE=1 SV=2 CANONICAL=A0A5G2R986-1" }, "locus": { "chromosome": "15", "start_pos": 119985893, "end_pos": 119952802, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067013.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067013.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066247.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066247.2" } ] } }, { "isoform_ac": "A0A5G2QNI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986/entry#A0A5G2QNI3-1", "sequence": { "sequence": "MSVSRSTEDSCELDLVYVTERIIAVSFPSTANEDNFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITRLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNVQGDSQTSICITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFNGHRDDGMEEVVGHTQGPLDGSLYAKVKKKDSLNGSTSAVNATRPVLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPAPGPSSAQAALSPEEKRELDRLLSGFGLEREKQGSMYHTQHLRSRPGEGPAAPSSGRHIIPAQVHVNGGALASERETDILDDELPNQDGHSVGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKPYSVEPMVNGGGYPYESASRVVPAQAGHMAPMRPSYSAQEGLAGHQREGPHPGWSQSMTTSHYGHDPSGMFRSQSFPESEPQLPPAPARGGSSREAVQRGLNCWQQQQQQQQQQQPRPPPRQQERAHLESLGLSRPSPQPLAEPPMPGLPEFPRAASQQEIEQSIETLNMLMLDLEPAAAAAAPLHKSQSVPGAWPGASPLSSQPLSGSSYQSHPLTQSRSGYIPSGNSLATPEPIPRASLESVPSGRSYSPYDYQPCPSGPNQSYRPKSPSSSGPQQPPASLPGLTAQPRLPPKEMTPDPSRTPEEEPLNLGGVQAREKQPAEPPAPLRRRAASDGQYENQSPEPTSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPTSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGEEDEGKVVTKLSKEPRSYVESVVRTAVAGPRTQDAEPKSFSAPAAQAYGHETPLRNGTLGGSFVSPSPLSTSSPILSADGTSVGSFPSGENGDPGPRTPTQPLLDSGFRATGSLGQPSPSAQRSYQSSSPIPAAGSSYHSPDYALQQFGSPESQARSQFSVAGVHAVPGSPQARHRTVGTNTPPSPGFGRRAVNPSMAAPSSPSLSHRQVMGPPGPGFHGNAVSSPQSSAATTPGSPSLGRHPGAHQVSSLHGNVATTPGSPSLGRHPGAHQGNLASSLHGNAIPSPGSPSLGRHLGGSGSVVPGSPSLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSMGDRAGSLPNYATVNGKVSSSPVPSGMSSPSGGSTVSFSHTLPDFSKCSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGPANSTSDLLKQGAACNVLFLNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQDRKWVKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLSAGQKR", "length": 1709, "header": "tr|A0A5G2QNI3-1|A0A5G2R986_PIG Computationally mapped isoform of Tensin 1 OS=Sus scrofa OX=9823 GN=TNS1 PE=1 SV=2 CANONICAL=A0A5G2R986-1" }, "locus": { "chromosome": "15", "start_pos": 120047044, "end_pos": 119952802, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074371.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074371.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066244.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066244.2" } ] } }, { "isoform_ac": "A0A5G2R986-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986/entry#A0A5G2R986-1", "sequence": { "sequence": "MTRLSWCFSCVIRWSKYLFSCFLPLRFCLRRQPEDLEAPKTHHFKVKTFKKVKPCGICRQVITREGCTCKEGAFRGGNTRKNLEEDVSMRRGRRKIPLSACCLPRNMSVSRSTEDSCELDLVYVTERIIAVSFPSTANEDNFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITRLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNVQGDSQTSICITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFNGHRDDGMEEVVGHTQGPLDGSLYAKVKKKDSLNGSTSAVNATRPVLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPAPGPSSAQAALSPEEKRELDRLLSGFGLEREKQGSMYHTQHLRSRPGEGPAAPSSGRHIIPAQVHVNGGALASERETDILDDELPNQDGHSVGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKPYSVEPMVNGGGYPYESASRVVPAQAGHMAPMRPSYSAQEGLAGHQREGPHPGWSQSMTTSHYGHDPSGMFRSQSFPESEPQLPPAPARGGSSREAVQRGLNCWQQQQQQQQQQQPRPPPRQQERAHLESLGLSRPSPQPLAEPPMPGLPEFPRAASQQEIEQSIETLNMLMLDLEPAAAAAAPLHKSQSVPGAWPGASPLSSQPLSGSSYQSHPLTQSRSGYIPSGNSLATPEPIPRASLESVPSGRSYSPYDYQPCPSGPNQSYRPKSPSSSGPQQPPASLPGLTAQPRLPPKEMTPDPSRTPEEEPLNLGGVQAREKQPAEPPAPLRRRAASDGQYENQSPEPTSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPTSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGEPRSYVESVVRTAVAGPRTQDAEPKSFSAPAAQAYGHETPLRNGTLGGSFVSPSPLSTSSPILSADGTSVGSFPSGENGDPGPRTPTQPLLDSGFRATGSLGQPSPSAQRSYQSSSPIPAAGSSYHSPDYALQQFGSPESQARSQFSVAGVHAVPGSPQARHRTVGTNTPPSPGFGRRAVNPSMAAPSSPSLSHRQVMGPPGPGFHGNAVSSPQSSAATTPGSPSLGRHPGAHQVSSLHGNVATTPGSPSLGRHPGAHQGNLASSLHGNAIPSPGSPSLGRHLGGSGSVVPGSPSLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSMGDRAGSLPNYATVNGKVSSSPVPSGMSSPSGGSTVSFSHTLPDFSKCSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGPANSTSDLLKQGAACNVLFLNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQDRKWVKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLSAGQKR", "length": 1802, "header": "tr|A0A5G2R986-1|A0A5G2R986_PIG Isoform 1 of Tensin 1 OS=Sus scrofa OX=9823 GN=TNS1 PE=1 SV=2 CANONICAL=A0A5G2R986-1" }, "locus": { "chromosome": "15", "start_pos": 120164514, "end_pos": 119952802, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076370.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076370.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073636.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073636.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1416, "start_aa": "Thr", "end_pos": 1416, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1416", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1449, "start_aa": "Thr", "end_pos": 1449, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1449", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1698, "start_aa": "Thr", "end_pos": 1698, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1698", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QNI3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNI3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R986", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R986", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R986", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fibroblast migration", "id": "GO:0010761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010761", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R986", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1130, "end_pos": 1132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1654, "end_pos": 1656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 915, "end_pos": 917, "annotation": "n_glycosylation_sequon" }, { "start_pos": 993, "end_pos": 995, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986" }, { "id": "PS51182", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51182" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 tensin-type", "eco_id": "ECO_0000259", "start_pos": 287, "end_pos": 413, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986" }, { "id": "PS51181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatase tensin-type", "eco_id": "ECO_0000259", "start_pos": 110, "end_pos": 282, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R986" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 1530, "end_pos": 1639, "start_aa": "Trp", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1416, 1449, 1698 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 1130, "end_pos": 1132 }, { "start_pos": 1654, "end_pos": 1656 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 489, "end_pos": 491 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 633, "end_pos": 635 }, { "start_pos": 915, "end_pos": 917 }, { "start_pos": 993, "end_pos": 995 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RCB2-1", "uniprot_ac": "A0A5G2RCB2", "uniprot_id": "A0A5G2RCB2_PIG", "mass": { "chemical_mass": 79375.0, "monoisotopic_mass": 79375.0 }, "refseq": {}, "gene_names": [ { "name": "MEP1A", "type": "recommended", "evidence": [ { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" } ] } ], "protein_names": [ { "name": "Meprin A subunit", "type": "recommended", "evidence": [ { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2/entry#names_and_taxonomy" } ] }, { "name": "3.4.24.-", "type": "synonym", "evidence": [ { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2/entry#names_and_taxonomy" } ] }, { "name": "Endopeptidase-2", "type": "synonym", "evidence": [ { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MEP1A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2", "locus": {} } ], "crossref": [ { "id": "A0A5G2RCB2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCB2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001724", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001724", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04282", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04282", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100154136", "url": "https://www.ncbi.nlm.nih.gov/gene/100154136", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006026", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006026", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FEMFRLR", "url": "https://omabrowser.org/oma/group/FEMFRLR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10127:SF824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10127:SF824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00629", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00629", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22486", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22486", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QPZ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYN6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQN6", "url": "https://www.uniprot.org/uniprotkb/F1RQN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQN6-1", "url": "https://www.uniprot.org/uniprotkb/F1RQN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QPWAGLTFALFLQNSRNGLRDPNTRWKFPIPYILANNLALNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQKFDGCWSEVGDQHVGQNLSIGQGCDYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDEILPGYQHNFNTYDDNFITDLNTPYDYESLMHYGPFSFNKNDSVPTITTKIPEFNTIIGQRLDFSEVDLERLNRMYNCTTTHTFLDHCAFEKANICGMIQGTRDDADWVHEDSAQPGQVDHTLGGQCTGAGYFMHFDTSSGAVEEAALLESRILYPKRKQQCLQFFYKMTGSSSDRLVVWVRRDDGTGNVRKLVKMKTFQGDFDQNWKIAHVPLREEKKFRYLFQGTKGDPQNSNGGIYLDDVTLTETPCPTGVWTVRNFSQVLQDTVQGDKLQSPRFYSSEGYGLGLTLYPHGGMNSEHSEYVGLAFHLCSGENDAVLEWPVENRQVIMTILDQEPDVRKRMSSSMVFTTSKSQTSAAINGSVIWDRPSIVGSYHNSCDCFRTIDWGWSGVISHQMLKRKSFLKNNDLILFVDFEDITHLNQTEVDVKDSRLTPRGLILQGQEQQVSEEASRKASLEKALLESPAQGHSGRQKRSVDNTGPLEDPTWPQYFRDPCDPNPCQNEGICVNVKGMASCRCVSSRAFFYTGERCQAMQVHGSILGLMLGGAASLILSFTIVSILHQRPRQ", "length": 699, "header": "tr|A0A5G2RCB2-1|A0A5G2RCB2_PIG Isoform 1 of Meprin A subunit OS=Sus scrofa OX=9823 GN=MEP1A PE=1 SV=1 CANONICAL=A0A5G2RCB2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QPZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2/entry#A0A5G2QPZ8-1", "sequence": { "sequence": "MIWTRSPCILSFILFFAHIAAVSVIHDGDFDEQKDITEINLGGFTFALFLQNSRNGLRDPNTRWKFPIPYILANNLALNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQKFDGCWSEVGDQHVGQNLSIGQGCDYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDEILPGYQHNFNTYDDNFITDLNTPYDYESLMHYGPFSFNKNDSVPTITTKIPEFNTIIGQRLDFSEVDLERLNRMYNCTTTHTFLDHCAFEKANICGMIQGTRDDADWVHEDSAQPGQVDHTLGGQCTGAGYFMHFDTSSGAVEEAALLESRILYPKRKQQCLQFFYKMTGSSSDRLVVWVRRDDGTGNVRKLVKMKTFQGDFDQNWKIAHVPLREEKKFRYLFQGTKGDPQNSNGGIYLDDVTLTETPCPTGVWTVRNFSQVLQDTVQGDKLQSPRFYSSEGYGLGLTLYPHGGMNSEHSEYVGLAFHLCSGENDAVLEWPVENRQVIMTILDQEPDVRKRMSSSMVFTTSKSQTSAAINGSVIWDRPSIVGSYHNSCDCFRTIDWGWSGVISHQMLKRKSFLKNNDLILFVDFEDITHLNQTEVDVKDSRLTPRGLILQGQEQQVSEEASRKASLEKALLESPAQGHSGRQKRSVDNTGPLEDPTWPQYFRDPCDPNPCQNEGICVNVKGMASCRYAPWPAGGRSESAARGLLMRPKRRSQGRAPTTKAGSDAPELCPESAGRAGVLPGQRSPLSPVS", "length": 750, "header": "tr|A0A5G2QPZ8-1|A0A5G2RCB2_PIG Computationally mapped isoform of Meprin A subunit OS=Sus scrofa OX=9823 GN=MEP1A PE=1 SV=2 CANONICAL=A0A5G2RCB2-1" }, "locus": { "chromosome": "7", "start_pos": 41619985, "end_pos": 41587761, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082046.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082046.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066970.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066970.2" } ] } }, { "isoform_ac": "A0A5G2QYN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2/entry#A0A5G2QYN6-1", "sequence": { "sequence": "MIWTRSPCILSFILFFAHIAAVSIKHLSKGNVHDGDFDEQKDITEINLDAGLDLFQGDILLQNSRNGLRDPNTRWKFPIPYILANNLALNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQKFDGCWSEVGDQHVGQNLSIGQGCDYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDEILPGYQHNFNTYDDNFITDLNTPYDYESLMHYGPFSFNKNDSVPTITTKIPEFNTIIGQRLDFSEVDLERLNRMYNCTTTHTFLDHCAFEKANICGMIQGTRDDADWVHEDSAQPGQVDHTLGGQCTGAGYFMHFDTSSGAVEEAALLESRILYPKRKQQCLQFFYKMTGSSSDRLVVWVRRDDGTGNVRKLVKMKTFQGDFDQNWKIAHVPLREEKKFRYLFQGTKGDPQNSNGGIYLDDVTLTETPCPTGVWTVRNFSQVLQDTVQGDKLQSPRFYSSEGYGLGLTLYPHGGMNSEHSEYVGLAFHLCSGENDAVLEWPVENRQVIMTILDQEPDVRKRMSSSMVFTTSKSQTSAAINGSVIWDRPSIVGSYHNSCDCFRTIDWGWSGVISHQMLKRKSFLKNNDLILFVDFEDITHLNQTEVDVKDSRLTPRGLILQGQEQQVSEEASRKASLEKALLESPAQGHSGRQKRSVDNTGPLEDPTWPQYFRDPCDPNPCQNEGICVNVKGMASCRYAPWPAGGRSESAARGLLMRPKRRSQGRAPTTKAGSDAPELCPESAGRAGVLPGQRSPLSPVS", "length": 761, "header": "tr|A0A5G2QYN6-1|A0A5G2RCB2_PIG Computationally mapped isoform of Meprin A subunit OS=Sus scrofa OX=9823 GN=MEP1A PE=1 SV=1 CANONICAL=A0A5G2RCB2-1" }, "locus": { "chromosome": "7", "start_pos": 41619985, "end_pos": 41587761, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068097.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068097.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067057.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067057.1" } ] } }, { "isoform_ac": "A0A5G2RCB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2/entry#A0A5G2RCB2-1", "sequence": { "sequence": "QPWAGLTFALFLQNSRNGLRDPNTRWKFPIPYILANNLALNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQKFDGCWSEVGDQHVGQNLSIGQGCDYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDEILPGYQHNFNTYDDNFITDLNTPYDYESLMHYGPFSFNKNDSVPTITTKIPEFNTIIGQRLDFSEVDLERLNRMYNCTTTHTFLDHCAFEKANICGMIQGTRDDADWVHEDSAQPGQVDHTLGGQCTGAGYFMHFDTSSGAVEEAALLESRILYPKRKQQCLQFFYKMTGSSSDRLVVWVRRDDGTGNVRKLVKMKTFQGDFDQNWKIAHVPLREEKKFRYLFQGTKGDPQNSNGGIYLDDVTLTETPCPTGVWTVRNFSQVLQDTVQGDKLQSPRFYSSEGYGLGLTLYPHGGMNSEHSEYVGLAFHLCSGENDAVLEWPVENRQVIMTILDQEPDVRKRMSSSMVFTTSKSQTSAAINGSVIWDRPSIVGSYHNSCDCFRTIDWGWSGVISHQMLKRKSFLKNNDLILFVDFEDITHLNQTEVDVKDSRLTPRGLILQGQEQQVSEEASRKASLEKALLESPAQGHSGRQKRSVDNTGPLEDPTWPQYFRDPCDPNPCQNEGICVNVKGMASCRCVSSRAFFYTGERCQAMQVHGSILGLMLGGAASLILSFTIVSILHQRPRQ", "length": 699, "header": "tr|A0A5G2RCB2-1|A0A5G2RCB2_PIG Isoform 1 of Meprin A subunit OS=Sus scrofa OX=9823 GN=MEP1A PE=1 SV=1 CANONICAL=A0A5G2RCB2-1" }, "locus": { "chromosome": "7", "start_pos": 41624379, "end_pos": 41592810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079416.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079416.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074021.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074021.1" } ] } }, { "isoform_ac": "F1RQN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2/entry#F1RQN6-1", "sequence": { "sequence": "MPYAGLDLFQGDILLQNSRNGLRDPNTRWKFPIPYILANNLALNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQKFDGCWSEVGDQHVGQNLSIGQGCDYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDEILPGYQHNFNTYDDNFITDLNTPYDYESLMHYGPFSFNKNDSVPTITTKIPEFNTIIGQRLDFSEVDLERLNRMYNCTTTHTFLDHCAFEKANICGMIQGTRDDADWVHEDSAQPGQVDHTLGGQCTGAGYFMHFDTSSGAVEEAALLESRILYPKRKQQCLQFFYKMTGSSSDRLVVWVRRDDGTGNVRKLVKMKTFQGDFDQNWKIAHVPLREEKKFRYLFQGTKGDPQNSNGGIYLDDVTLTETPCPTGVWTVRNFSQVLQDTVQGDKLQSPRFYSSEGYGLGLTLYPHGGMNSEHSEYVGLAFHLCSGENDAVLEWPVENRQVIMTILDQEPDVRKRMSSSMVFTTSKSQTSAAINGSVIWDRPSIVGSYHNSCDCFRTIDWGWSGVISHQMLKRKSFLKNNDLILFVDFEDITHLNQTEVDVKDSRLTPRGLILQGQEQQVSEEASRKASLEKALLESPAQGHSGRQKRSVDNTGPLEDPTWPQYFRDPCDPNPCQNEGICVNVKGMASCRCVSSRAFFYTGERCQAMQVHGSILGLMLGGAASLILSFTIVSILHQRPRQ", "length": 702, "header": "tr|F1RQN6-1|A0A5G2RCB2_PIG Computationally mapped isoform of Meprin A subunit OS=Sus scrofa OX=9823 GN=MEP1A PE=1 SV=3 CANONICAL=A0A5G2RCB2-1" }, "locus": { "chromosome": "7", "start_pos": 41624379, "end_pos": 41588613, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001928.3", "url": "https://www.ensembl.org/id/ENSSSCT00000001928.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001881.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001881.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQN6", "url": "https://www.uniprot.org/uniprotkb/F1RQN6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P28825-1", "protein_name": "Meprin A subunit alpha", "gene_name": "Mep1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWIQPACLLSLIFSAHIAAVSIKHLLNGSDHDTDVGEQKDIFEINLAAGLNLFQGDILLPRTRNAMRDPSSRWKLPIPYILADNLELNAKGAILHAFEMFRLKSCVDFKPYEGESSYIIFQKLSGCWSMIGDQQVGQNISIGEGCDFKATIEHEILHALGFFHEQSRTDRDDYVNIWWDQIITDYEHNFNTYDDNTITDLNTPYDYESLMHYGPFSFNKNESIPTITTKIPEFNTIIGQLPDFSAIDLIRLNRMYNCTATHTLLDHCDFEKTNVCGMIQGTRDDADWAHGDSSQPEQVDHTLVGQCKGAGYFMFFNTSLGARGEAALLESRILYPKRKQQCLQFFYKMTGSPADRFEVWVRRDDNAGKVRQLAKIQTFQGDSDHNWKIAHVTLNEEKKFRYVFLGTKGDPGNSSGGIYLDDITLTETPCPAGVWTIRNISQILENTVKGDKLVSPRFYNSEGYGVGVTLYPNGRITSNSGFLGLTFHLYSGDNDAILEWPVENRQAIMTILDQEADTRNRMSLTLMFTTSKNQTSSAINGSVIWDRPSKVGVYDKDCDCFRSLDWGWGQAISHQLLKRRNFLKGDSLIIFVDFKDLTHLNRTEVPASARSTMPRGLLLQGQESPALGESSRKAMLEESLPSSLGQRHPSRQKRSVENTGPMEDHNWPQYFRDPCDPNPCQNEGTCVNVKGMASCRCVSGHAFFYAGERCQAMHVHGSLLGLLIGCIAGLIFLTFVTFSTTNGKLRQ", "length": 747 }, "evidence": [ { "id": "A0A5G2RCB2", "url": "https://omabrowser.org/oma/group/A0A5G2RCB2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q16819-1", "protein_name": "Meprin A subunit alpha", "gene_name": "MEP1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAWIRSTCILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDILLQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLSQTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGPLEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGTAGVIFLTFSIIAILSQRPRK", "length": 746 }, "evidence": [ { "id": "A0A5G2RCB2", "url": "https://omabrowser.org/oma/group/A0A5G2RCB2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64230-1", "protein_name": "Meprin A subunit alpha", "gene_name": "Mep1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWTLPVCLLSLSFSAHIAAVSIQHLSTGHDHDDVDVGEQQKDISEINSAAGLNLFQGDILLPRTRNALRDPSSRWKLPIPYILADNLDLNAKGAILNAFEMFRLKSCVDFKPYEGESSYIIFQQFSGCWSMVGDQHVGQNISIGEGCDYKAIIEHEILHALGFFHEQSRTDRDDYVNIWWNEIMTDYEHNFNTYDDKTITDLNTPYDYESLMHYGPFSFNKNETIPTITTKIPEFNAIIGQRLDFSATDLTRLNRMYNCTRTHTLLDHCAFEKTNICGMIQGTRDDADWVHEDSSQPGQVDHTLVGRCKAAGYFMYFNTSSGVTGEVALLESRILYPKRKQQCLQFFYKMTGSPADRLLIWVRRDDNTGNVCQLAKIQTFQGDSDHNWKIAHVTLNEEKKFRYVFQGTKGDPGNSDGGIYLDDITLTETPCPTGVWTIRNISQVLENTVKGDRLVSPRFYNSEGYGFGVTLYPNGRITSNSGYLGLAFHLYSGDNDVILEWPVENRQAIMTILDQEPDARNRMSLSLMFTTSKYQTSSAINGSVIWDRPTKVGVYDKDCDCFRSIDWGWGQAISHQMLMRRNFLKDDTLIIFVDFKDLTHLRQTEVPIPSRSVIPRGLLLQGQEPLALGDSRIAMMEESLPRRLDQRQPSRPKRSVENTGPMEDHNWPQYFRDPCDPNPCQNEGTCVNVKGMASCRCVSGHAFFYTGERCQAMHVHGSLLGLLIGCITALIFLTFITFSNTYQKLRQ", "length": 748 }, "evidence": [ { "id": "A0A5G2RCB2", "url": "https://omabrowser.org/oma/group/A0A5G2RCB2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" } ], "pmid": "" }, { "name": "signaling receptor ligand precursor processing", "id": "GO:0140448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140448", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 554, "end_pos": 556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RCB2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 699, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RCB2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCB2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 624, "end_pos": 664, "start_aa": "Phe", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" }, { "id": "PS50060", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50060" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MAM", "eco_id": "ECO_0000259", "start_pos": 218, "end_pos": 384, "start_aa": "Asp", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" }, { "id": "PS50144", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50144" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MATH", "eco_id": "ECO_0000259", "start_pos": 382, "end_pos": 547, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" }, { "id": "PS51864", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51864" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M12A", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 211, "start_aa": "Asn", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2#function" }, { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" }, { "id": "PRU01211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01211" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 106, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 106, "end_pos": 106, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1RQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQN6#function" }, { "id": "F1RQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQN6" }, { "id": "PRU01211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01211" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 109, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 109, "end_pos": 109, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2#function" }, { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" }, { "id": "PRU01211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01211" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 110, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 110, "end_pos": 110, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1RQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQN6#function" }, { "id": "F1RQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQN6" }, { "id": "PRU01211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01211" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 113, "amino_acid": "Gly", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 113, "end_pos": 113, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2#function" }, { "id": "A0A5G2RCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB2" }, { "id": "PRU01211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01211" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 116, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 116, "end_pos": 116, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1RQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQN6#function" }, { "id": "F1RQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQN6" }, { "id": "PRU01211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01211" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 119, "amino_acid": "Ser", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 119, "end_pos": 119, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1RQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQN6#function" }, { "id": "F1RQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQN6" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 12, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 12, "end_pos": 12, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QPZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPZ8#function" }, { "id": "A0A5G2QPZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPZ8" }, { "id": "PRU01211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01211" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 144, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 144, "end_pos": 144, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QPZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPZ8#function" }, { "id": "A0A5G2QPZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPZ8" }, { "id": "PRU01211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01211" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 148, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 148, "end_pos": 148, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QPZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPZ8#function" }, { "id": "A0A5G2QPZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPZ8" }, { "id": "PRU01211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01211" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 154, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 154, "end_pos": 154, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QYN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN6#function" }, { "id": "A0A5G2QYN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN6" }, { "id": "PRU01211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01211" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 155, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 155, "end_pos": 155, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QYN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN6#function" }, { "id": "A0A5G2QYN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN6" }, { "id": "PRU01211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01211" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 159, "amino_acid": "Tyr", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 159, "end_pos": 159, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QYN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN6#function" }, { "id": "A0A5G2QYN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN6" }, { "id": "PRU01211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01211" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 165, "amino_acid": "Tyr", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 165, "end_pos": 165, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2QYN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN6#function" }, { "id": "A0A5G2QYN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYN6" }, { "id": "PIRSR001196-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001196-2" } ], "binding_site_uniprot": 58, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 58, "end_pos": 58, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 }, { "start_pos": 209, "end_pos": 211 }, { "start_pos": 391, "end_pos": 393 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 554, "end_pos": 556 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RFE6-1", "uniprot_ac": "A0A5G2RFE6", "uniprot_id": "A0A5G2RFE6_PIG", "mass": { "chemical_mass": 135628.0, "monoisotopic_mass": 135628.0 }, "refseq": {}, "gene_names": [ { "name": "ZC3H4", "type": "recommended", "evidence": [ { "id": "A0A5G2RFE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH domain-containing protein 4", "type": "recommended", "evidence": [ { "id": "A0A5G2RFE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "RNA-binding protein that suppresses transcription of long non-coding RNAs (lncRNAs). LncRNAs are defined as transcripts more than 200 nucleotides that are not translated into protein. Together with WDR82, part of a transcription termination checkpoint that promotes transcription termination of lncRNAs and their subsequent degradation by the exosome. The transcription termination checkpoint is activated by the inefficiently spliced first exon of lncRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6#function" }, { "database": "UniProtKB", "id": "ARBA00059523", "url": "https://www.uniprot.org/uniprotkb/ARBA00059523#function" }, { "database": "UniProtKB", "id": "F1RM04", "url": "https://www.uniprot.org/uniprotkb/F1RM04#function" }, { "database": "UniProtKB", "id": "A0A8W4FHD8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHD8#function" }, { "database": "UniProtKB", "id": "A0A5G2QQC3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQC3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZC3H4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6", "locus": { "chromosome": "6", "start_pos": 52894951, "end_pos": 52938164, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003110", "url": "https://www.ensembl.org/id/ENSSSCG00000003110" } ] } } ], "crossref": [ { "id": "A0A5G2RFE6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFE6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003110", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003110", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SHQQSDK", "url": "https://omabrowser.org/oma/group/SHQQSDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13119:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13119:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22623", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22623", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9930044", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9930044", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QQC3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FHD8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FHD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RM04", "url": "https://www.uniprot.org/uniprotkb/F1RM04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RM04-1", "url": "https://www.uniprot.org/uniprotkb/F1RM04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAPGTPPPPPSESPPPPSPPLPSTPSPPPCSPDACPATPHLLHHRLPLPDDRSGPRPGRGSVPGGRKRRRRRKGGGRHVGPGHGGGGGGGGGRAGSVGVSRSLALSRLLSLLASCVSPPSRRSPALPRSRSVFFGRHAEGKTILCLLKEMPPTFRDTSAAVWEDGELEEGELEDDGAEETQDTSGGPERSRKEKGDKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKGHRKYREYSPPYAPSHQQYPPSHTTPLPKKAYSKMDSKGYSMYEDYENEQYGEYEGDEEEDMGKDDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGDHPEDDEDFYEEEMEYGESEEPMGDEDYDDYSKELNQYRRSKDGRGRGLSRGRGRGSRGRGKGMGRGRGRGGSRGGMNKGGMNEDDDFYDEDMGDGGGGSYRRSDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYMHGDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPPAPTSPNGRPLQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPPGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYQQQEGMEMEPGLIGDTEDYGHYEELPGEPGEHLFPEHPLEPDSFSEGGPPGRPKPGAGVPDFLPSAQRALYLRIQQKQQEEEERARRLAESSKQDRENEEGDPGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASGGELSSSGLGDPRLQKGHPTGGRLADPRLSRDPRLSRHAEASGGSGPGDTGPSDPRLARSLPTPKPEGGLHSSPVGPSGSKGSGPPPAEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDAVPPVPVALQSMPALDPRLHRTTTTSGPPNPRQRPGTSTDPSASGSNLPDFELLSRILKTVNATGPSQPLVPVTSPVTPECERHPPTLGCRNQQTLPPPRGPPSLAPLKSLHPPAPAGSPPHQPLPPMTPECWQQAAWARAAGAGRAAC", "length": 1249, "header": "tr|A0A5G2RFE6-1|A0A5G2RFE6_PIG Isoform 1 of Zinc finger CCCH domain-containing protein 4 OS=Sus scrofa OX=9823 GN=ZC3H4 PE=1 SV=1 CANONICAL=A0A5G2RFE6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6/entry#A0A5G2QQC3-1", "sequence": { "sequence": "MEAAPGTPPPPPSESPPPPSPPLPSTPSPPPCSPDACPATPHLLHHRLPLPDDRSGPRPGRGSVPGGRKRRRRRKGGGRHVGPGHGGGGGGGGGRAGSVGVSRSLALSRLLSLLASCVSPPSRRSPALPRSRSVFFGRHAEGKGLLSNPVFMSALGLVCREDGELEEGELEDDGAEETQDTSGGPERSRKEKGDKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKGHRKYREYSPPYAPSHQQYPPSHTTPLPKKAYSKMDSKGYSMYEDYENEQYGEYEGDEEEDMGKDDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGDHPEDDEDFYEEEMEYGESEEPMGDEDYDDYSKELNQYRRSKDGRGRGLSRGRGRGSRGRGKGMGRGRGRGGSRGGMNKGGMNEDDDFYDEDMGDGGGGSYRRSDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENSFALTCHERDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPPAPTSPNGRPLQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPPGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYQQQEGMEMEPGLIGDTEDYGHYEELPGEPGEHLFPEHPLEPDSFSEGGPPGRPKPGAGVPDFLPSAQRALYLRIQQKQQEEEERARRLAESSKQDRENEEGDPGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASGGELSSSGLGDPRLQKGHPTGGRLADPRLSRDPRLSRHAEASGGSGPGDTGPSDPRLARSLPTPKPEGGLHSSPVGPSGSKGSGPPPAEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDAVPPVPVALQSMPALDPRLHRTTTTSGPPNPRQRPGTSTDPSASGSNLPDFELLSRILKTVNATGPSQPLVPVTSPVTPECERHPPTLGCRNQQTLPPPRGPPSLAPLKSLHPPAPAGSPPHQPLPPMTPECWQQAAWARAAGAGRAAC", "length": 1248, "header": "tr|A0A5G2QQC3-1|A0A5G2RFE6_PIG Computationally mapped isoform of Zinc finger CCCH domain-containing protein 4 OS=Sus scrofa OX=9823 GN=ZC3H4 PE=1 SV=2 CANONICAL=A0A5G2RFE6-1" }, "locus": { "chromosome": "6", "start_pos": 52936960, "end_pos": 52897814, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081236.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081236.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060483.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060483.2" } ] } }, { "isoform_ac": "A0A5G2RFE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6/entry#A0A5G2RFE6-1", "sequence": { "sequence": "MEAAPGTPPPPPSESPPPPSPPLPSTPSPPPCSPDACPATPHLLHHRLPLPDDRSGPRPGRGSVPGGRKRRRRRKGGGRHVGPGHGGGGGGGGGRAGSVGVSRSLALSRLLSLLASCVSPPSRRSPALPRSRSVFFGRHAEGKTILCLLKEMPPTFRDTSAAVWEDGELEEGELEDDGAEETQDTSGGPERSRKEKGDKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKGHRKYREYSPPYAPSHQQYPPSHTTPLPKKAYSKMDSKGYSMYEDYENEQYGEYEGDEEEDMGKDDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGDHPEDDEDFYEEEMEYGESEEPMGDEDYDDYSKELNQYRRSKDGRGRGLSRGRGRGSRGRGKGMGRGRGRGGSRGGMNKGGMNEDDDFYDEDMGDGGGGSYRRSDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYMHGDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPPAPTSPNGRPLQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPPGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYQQQEGMEMEPGLIGDTEDYGHYEELPGEPGEHLFPEHPLEPDSFSEGGPPGRPKPGAGVPDFLPSAQRALYLRIQQKQQEEEERARRLAESSKQDRENEEGDPGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASGGELSSSGLGDPRLQKGHPTGGRLADPRLSRDPRLSRHAEASGGSGPGDTGPSDPRLARSLPTPKPEGGLHSSPVGPSGSKGSGPPPAEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDAVPPVPVALQSMPALDPRLHRTTTTSGPPNPRQRPGTSTDPSASGSNLPDFELLSRILKTVNATGPSQPLVPVTSPVTPECERHPPTLGCRNQQTLPPPRGPPSLAPLKSLHPPAPAGSPPHQPLPPMTPECWQQAAWARAAGAGRAAC", "length": 1249, "header": "tr|A0A5G2RFE6-1|A0A5G2RFE6_PIG Isoform 1 of Zinc finger CCCH domain-containing protein 4 OS=Sus scrofa OX=9823 GN=ZC3H4 PE=1 SV=1 CANONICAL=A0A5G2RFE6-1" }, "locus": { "chromosome": "6", "start_pos": 52936960, "end_pos": 52897814, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088705.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088705.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073512.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073512.1" } ] } }, { "isoform_ac": "A0A8W4FHD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6/entry#A0A8W4FHD8-1", "sequence": { "sequence": "MLGRATEEEEEEEEEGRGRWVSLARSLFLACFLSWPHAFPPPRGARGAPRTPRLEEGELEDDGAEETQDTSGGPERSRKEKGDKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKGHRKYREYSPPYAPSHQQYPPSHTTPLPKKAYSKMDSKGYSMYEDYENEQYGEYEGDEEEDMGKDDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGDHPEDDEDFYEEEMEYGESEEPMGDEDYDDYSKELNQYRRSKDGRGRGLSRGRGRGSRGRGKGMGRGRGRGGSRGGMNKGGMNEDDDFYDEDMGDGGGGSYRRSDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENSFALTCHERDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPPAPTSPNGRPLQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPPGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYQQQEGMEMEPGLIGDTGDPGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASGGELSSSGLGDPRLQKGHPTGGRLADPRLSRDPRLSRHAEASGGSGPGDTGPSDPRLARSLPTPKPEGGLHSSPVGPSGSKGSGPPPAEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDAVPPVPVALQSMPALDPRLHRTTTTSGPPNPRQRPGTSTDPSASGSNLPDFELLSRILKTVNATGPSQPLVPVTSPVTPECERHPPTLGCRNQQTLPPPRGPPSLAPLKSLHPPAPAGSPPHQPLPPMTPECWQQAAWARAAGAGRAAC", "length": 1053, "header": "tr|A0A8W4FHD8-1|A0A5G2RFE6_PIG Computationally mapped isoform of Zinc finger CCCH domain-containing protein 4 OS=Sus scrofa OX=9823 GN=ZC3H4 PE=1 SV=1 CANONICAL=A0A5G2RFE6-1" }, "locus": { "chromosome": "6", "start_pos": 52936722, "end_pos": 52897814, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096710.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096710.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078847.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078847.1" } ] } }, { "isoform_ac": "F1RM04-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6/entry#F1RM04-1", "sequence": { "sequence": "MEAAPGTPPPPPSESPPPPSPPLPSTPSPPPCSPDACPATPHLLHHRLPLPDDRSGPRPGRGSVPGGRKRRRRRKGGGRHVGPGHGGGGGGGGGRAGSVGVSRSLALSRLLSLLASCVSPPSRRSPALPRSRSVFFGRHAEGKTILCLLKEMPPTFRDTSAAVWEDGELEEGELEDDGAEETQDTSGGPERSRKEKGDKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKGHRKYREYSPPYAPSHQQYPPSHTTPLPKKAYSKMDSKGYSMYEDYENEQYGEYEGDEEEDMGKDDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGDHPEDDEDFYEEEMEYGESEEPMGDEDYDDYSKELNQYRRSKDGRGRGLSRGRGRGSRGRGKGMGRGRGRGGSRGGMNKGGMNEDDDFYDEDMGDGGGGSYRRSDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYMHGDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPPAPTSPNGRPLQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPPGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYQQQEGMEMEPGLIGDTGDPGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASGGELSSSGLGDPRLQKGHPTGGRLADPRLSRDPRLSRHAEASGGSGPGDTGPSDPRLARSLPTPKPEGGLHSSPVGPSGSKGSGPPPAEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDAVPPVPVALQSMPALDPRLHRTTTTSGPPNPRQRPGTSTDPSASGSNLPDFELLSRILKTVNATGPSQPLVPVTSPVTPECERHPPTLGCRNQQTLPPPRGPPSLAPLKSLHPPAPAGSPPHQPLPPMTPECWQQAAWARAAGAGRAAC", "length": 1165, "header": "tr|F1RM04-1|A0A5G2RFE6_PIG Computationally mapped isoform of Zinc finger CCCH domain-containing protein 4 OS=Sus scrofa OX=9823 GN=ZC3H4 PE=1 SV=3 CANONICAL=A0A5G2RFE6-1" }, "locus": { "chromosome": "6", "start_pos": 52936960, "end_pos": 52897814, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003449.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003449.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003366.3", "url": "https://www.ensembl.org/id/ENSSSCP00000003366.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 26, "start_aa": "Thr", "end_pos": 26, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr26", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 629, "start_aa": "Thr", "end_pos": 629, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr629", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 640, "start_aa": "Thr", "end_pos": 640, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr640", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQC3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQC3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9930044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9930044", "resource": "Reactome", "description": "Nuclear RNA decay" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G746-1", "protein_name": "Zinc finger CCCH domain-containing protein 4", "gene_name": "Zc3h4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPGTPPPPPSESPPPPSPPPPSTPSPPPCSPDCRAATPHLLHHRLPLPDDREDGELEEGELEDDGAEDIQDTPGGQERSRKEKGEKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKGHRKYRDYSPPYVPSHQQYSSSHNTPLPKKSYSKIDSKGYSMYEDYENEQYGEYEGDEEEDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGEHPEDEEDLYDEEIEYGESEEPMGDDDYDEYSKELNQYRRSKDSRGRGLSRGRGRGSRGGRGKGMGRGRGRGSRGGMSKGGMNDEDDFYDDDMGDGGGGSYRRSDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYIHERDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPPAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMAMPAHEPLSPQQLQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPSGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMHPDMHPDMHPDMHPDMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMAPIPPAQNFYENFYPQQEGMEMEPGLVGDAEDYGHYEELPGQPGEPLFPEHPLEPDSFPEGGPPGRPKAGAGVPDFLPSAQRALYLRIQQKQQEEERARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASVGEPSSSGLGDPRLQKGHTTGGRLADPRLSRDPRLSRHAETSGGSGPGDSGPSDPRLARALPTSKTEGSLHSSPACPSGSKGQPPAEEEEGERALREKAVTIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDVPPVPAALQSLPALDPRLHRSTPPGPPNTRQQRPGSTDPSTSGSNLPDFELLSRILKTVNVNTPGQSEKPSDPRVRKTPTDPRLQKPADPGAASRAAKPCPTEASPPAASPSGDSPPATAPYDPRVLAAGGLGQGSSSGQSSVLSGISLYDPRTPNAGGKTAELTSDTSAQPKGPEGNGKSSASKAKEPPFVRKSALEQPETGKASTDGATATDRYNSYNRPRPKATAAPTAASSTPPPEGATTQPGVHNLPVPTLFGTVKPTPKTGTGSPFAGNSPAREGEQDAGSLKDVFKGFDPTASPFCQ", "length": 1305 }, "evidence": [ { "id": "A0A5G2RFE6", "url": "https://omabrowser.org/oma/group/A0A5G2RFE6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FGZ9-1", "protein_name": "Zinc finger CCCH domain-containing protein 4", "gene_name": "zc3h4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVESMTVHPNSPTANHEHNSLLTDERQEDGELEEGELEDDGGEAEVPSGEVADPQDKPRHSKERHASESNDEEKSHRRRRKRKREREREKEKRRAKKKRKSKHKRHQSSSDEYSDYSDESDYSPSEKRKYREYSPPYPPTSQGGYSSAPSGHGGPMSKKGGYMKIDKQGYGGYDDYEEETYEGEDDEDMGDDDYDDFAKELNQYRKAKEVGGPRGRGGKNRMKNLRGRGRGGMRGRGGRGGGRGRGRGKMGGENDDGDGMYGEDMEYGDDDYDNMGDDDYDDYSKELNQYRKTKDRGRGGKGGRGRGRGKGGRGMNRGRGRNRGRGRGGDQGPDDDNSGDKDMDGSGPPRRNDQEKHGPEKKGKAICKYYIEGRCTWGDHCNFSHDIELPKKKELCKFYITGFCARAENCPYMHGDFPCKLFHTTGNCVNGEECMFSHDSLTEDTQELLDKMLAEDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPSPGDSSTPMEFGMPSAPHGNIPPSGPPAPGPGVGPVPGPGPGPGPGPGIGPCPVPPPPCTDGGTFQGPPPTGPPPPMGPPPVCGGNAGKKIPSLFEIVVKPTGQLAQKLGVRGPVPANASAGTAGPQGPPPGPPGAPPPRFPPPPGHMGPGGPHERPPMGPSNMNQGPPSMGTGPPMMQNFVQGEGPPNPGMMSPGAGSAGNNFYDNFYQQQQAMSIDGSGRDCDNFQGMGGGNFNDQSPGNHNSGSMESGANVGPSNQTGMAVPDFLPPAQRVLFMRLQQKQQEDEERARRLADGGGTERENEGGDSANWYSSEDEDGGGSVTSILKTLRQQTQNQGPAKPDGAPSDPRLQKSQPTPAPSRPADPRLARDPRLSRNTDSSQAPEASSSLSPTPSDPRLARHAAAHASKPEPPLVYKPPPLTAPASNEEEEGERMLRDKPVPIPLDPLMGMALRDPRSQLQQFSHIKKDVVLQKPSFSKAVLWSPEDLIPIPIPKQDLLPLPPGIPPVTTIDPRLSRTQPPHHSSILPPTVVPPPAPVEQSNQSSSSLPDFELLSRILKTVNASSSSPVQGASTGISSPPSVSSEKPIDPRMARKTPADPRLQPQKSALKTTSEPLVPQGSPPTSSLSPPSSSPTIAPYDPRLLSAGGSVRSVGSASVGSSSGGTSVLSGISLYDPRSQGADKTEGSVATRNSSPPPEPKSSESTTASAKPKSKEPLFVRKSALDQPEPEKSSTEQTTDRYNSYNRPRPKPSPSPNAGTAAAPTATSGPSTAGQGTTVSAEQPAAVHNLPVSTLFTMVKQVNKPSGTGSPFGGSSPAQPDTAEQDNASLKDVFKGFDPTASPFCQ", "length": 1340 }, "evidence": [ { "id": "A0A5G2RFE6", "url": "https://omabrowser.org/oma/group/A0A5G2RFE6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZPZ3-1", "protein_name": "Zinc finger CCCH domain-containing protein 4", "gene_name": "Zc3h4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAVPGTPPPPPSESPPPPSPPPPSTPSPPPCSPDGRAATPHLLHHRLPLPDDREDGELEEGELEDDGAEEVQDPPGGQERSRKEKGEKHHSDSEEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKSHRKYRDYSPPYAPSHQQYSSSHNAPLPKKSYSKMDSKGYSMYEDYENEQYGEYEGDEEEDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGEHPEDEEDLYEEEIEYGESEEPMGDDDYDDYSKELNQYRRSKDSRGRGLSRGRGRGSRGGRGKGMGRGRGRGGRGGMSKGGMNDDEDFYDDDMGDGGGGSYRRSDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYMHGDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPPAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMSLPTHEPLSPQQLQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPSGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMHPDMHPDMHPDMHPDMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYPQQEGMEMEPGLVGDAEDYGHYEELPGQPGEPLFPEHPLEPDSFPEGGPPGRPKAGAGVPDFLPSAQRALYLRIQQKQQEEERARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASVGEPSSSGLGDPRLQKGHPTGSRLSDPRLSRDPRLSRHAETSGGSGPGDSGPSDPRLARALPTSKAEGSLHSSPAGPSSSKGQPPAEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDVPPVPAALQSLPALDPRLHRSTPPGPPNTRQRPGSTDPSTSGSNLPDFELLSRILKTVNVNTPGQSEKPSDPRVRKTPTDPRLQKPADPVAASRAAKPCPTEASPPAASPSGDSSPPATAPYDPRVLAAGGLGQGSSSGQSSVLSGISLYDPRTPNAGGKTAEPASDTSAQPKGPEGNGKGSASKAKEPPFVRKSALEQPETGKASTDGATATDRYNSYNRPRPKATAAPTAASSTPPPEGATPQPGVHNLPVPTLFGTVKPAPKTGTGSPFAGNSPAREGEQDAGSLKDVFKGFDPTASPFCQ", "length": 1304 }, "evidence": [ { "id": "A0A5G2RFE6", "url": "https://omabrowser.org/oma/group/A0A5G2RFE6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UPT8-1", "protein_name": "Zinc finger CCCH domain-containing protein 4", "gene_name": "ZC3H4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAAPGTPPPPPSESPPPPSPPPPSTPSPPPCSPDARPATPHLLHHRLPLPDDREDGELEEGELEDDGAEETQDTSGGPERSRKEKGEKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKGHRKYREYSPPYAPSHQQYPPSHATPLPKKAYSKMDSKSYGMYEDYENEQYGEYEGDEEEDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGDHPEDEEDFYEEEMDYGESEEPMGDDDYDEYSKELNQYRRSKDSRGRGLSRGRGRGSRGRGKGMGRGRGRGGSRGGMNKGGMNDDEDFYDEDMGDGGGGSYRSRDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYMHGDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPQAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPPGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHADMHADMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYQQQEGMEMEPGLLGDAEDYGHYEELPGEPGEHLFPEHPLEPDSFSEGGPPGRPKPGAGVPDFLPSAQRALYLRIQQKQQEEEERARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSVTSILKTLRQQTSSRPPASVGELSSSGLGDPRLQKGHPTGSRLADPRLSRDPRLTRHVEASGGSGPGDSGPSDPRLARALPTSKPEGSLHSSPVGPSSSKGSGPPPTEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDAVPPVPAALQSMPTLDPRLHRAATAGPPNARQRPGASTDSSTQGANLPDFELLSRILKTVNATGSSAAPGSSDKPSDPRVRKAPTDPRLQKPTDSTASSRAAKPGPAEAPSPTASPSGDASPPATAPYDPRVLAAGGLGQGGGGGQSSVLSGISLYDPRTPNAGGKATEPAADTGAQPKGAEGNGKSSASKAKEPPFVRKSALEQPETGKAGADGGTPTDRYNSYNRPRPKAAAAPAATTATPPPEGAPPQPGVHNLPVPTLFGTVKQTPKTGSGSPFAGNSPAREGEQDAASLKDVFKGFDPTASPFCQ", "length": 1303 }, "evidence": [ { "id": "A0A5G2RFE6", "url": "https://omabrowser.org/oma/group/A0A5G2RFE6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of DNA-templated transcription, elongation", "id": "GO:0032785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032785", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" }, { "name": "DNA-templated transcription termination", "id": "GO:0006353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006353", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" }, { "name": "nuclear RNA surveillance", "id": "GO:0071027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071027", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" }, { "name": "lncRNA catabolic process", "id": "GO:0110064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110064", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" }, { "name": "negative regulation of lncRNA transcription", "id": "GO:0140744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140744", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1162, "end_pos": 1164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RFE6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1249, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RFE6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFE6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RFE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFE6" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 500, "end_pos": 527, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 26, 629, 640 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1162, "end_pos": 1164 }, { "start_pos": 521, "end_pos": 523 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RC25-1", "uniprot_ac": "A0A5G2RC25", "uniprot_id": "A0A5G2RC25_PIG", "mass": { "chemical_mass": 117735.0, "monoisotopic_mass": 117735.0 }, "refseq": {}, "gene_names": [ { "name": "KIAA0319", "type": "recommended", "evidence": [ { "id": "A0A5G2RC25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25" } ] } ], "protein_names": [ { "name": "KIAA0319", "type": "synonym", "evidence": [ { "id": "A0A5G2RC25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KIAA0319", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25", "locus": { "chromosome": "7", "start_pos": 19383196, "end_pos": 19486265, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001091", "url": "https://www.ensembl.org/id/ENSSSCG00000001091" } ] } } ], "crossref": [ { "id": "A0A5G2RC25", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC25", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001091", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001091", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00146", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00146", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46182", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46182", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46182:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46182:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23597", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23597", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QQH5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RC25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RC25-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUE2", "url": "https://www.uniprot.org/uniprotkb/F1RUE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUE2-1", "url": "https://www.uniprot.org/uniprotkb/F1RUE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPTGVLSSLLLLVTFTACACMQCSEGRTYSNAIISPNLETNKIMRVPQTTPVVDCTSACCDLASCDLAWWFEGRCYLVSCPHKENCQPKQMGSIRSYLTFVLRPAQRPAQLLDPGEVLLNRGSPSGIWGDLPEDIRKDLPFLGQDRGLEEMSEYSDDYRELDQNLFQPSSKQEPRGSAEYTDWGLLPGGGSEGGFNSSAGDGPAASAEKQQEDPELHKLNASAWTPAPKHSPERSLLLPLVTAPASGEELEKETFQLQEPPSKGSAREVLMPSRSPPLASLEFSPATMEESPVSTVMPWSPEHSISTLPASTVPTESPLSEQPASTPTAPRAVKELMVSAGDNLIITLPENEVELKASVVPVPPAETTYNYEWSLISHPEDYQGEIKQRHMETLNVSHLSLGHYAFKVAVSSENGFGEGFVNVTVKPAARVNLPPRAVVSPERQELTLPLTSAFIDGSQSTDDTKIVSYHWEEINGPFREEKTSAESPVLQLSNLLPGNYTFRLTVTDSDGATNSTTAALIVHSAVDHPPIADAGPNQTITLPQNSITLNGNQSSDDHQIVLYEWSLGPGSESKEVAMQGVETPYLHLSAMEEGDYTFQLIVTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELVFPVESTTLDGSQSSDDHGIVFYHWEHLRGPSAVEMENMDQAIATVSGLQVGTYHFRLTVKDQEGLSSTTTLTVAVKKENNSPPRAQAGGRHVLVLPNNSITLDGSRSTDDQGIVSYLWIRDGQSPAAGDVIGGSDHSAALQLTNLVEGVYTFRLRVADGQGASDTDTATVEVRPDPKKSGLVELILQVGVGQLEQQKDTLVRQLAVLLDVLDSDIKVQRIQAHSDLSTVIVFYVQSGPPFQVLKAAEVARNLHRRLSKEKADFLLFKVLRIDTAGCLLKCSGHGHCDPITKRCICSQLWMENLIQRYIRDGESNCEWSVFYVTILALTLVVLTGGVTWLCICCCKRRKRTKIRKKTKYTILDNMDDQERMELRPKYGIKHRSTEHNSSLMVSESEFDSDQDTIFSRERMERGNPKVSMNGSLRNGAAFSYCSKDR", "length": 1074, "header": "tr|A0A5G2RC25-1|A0A5G2RC25_PIG Isoform 1 of KIAA0319 OS=Sus scrofa OX=9823 GN=KIAA0319 PE=4 SV=1 CANONICAL=A0A5G2RC25-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25/entry#A0A5G2QQH5-1", "sequence": { "sequence": "MPSQGQPRPSCACMQCSEGRTYSNAIISPNLETNKIMRVPQTTPVVDCTSACCDLASCDLAWWFEGRCYLVSCPHKENCQPKQMGSIRSYLTFVLRPAQRPAQLLDPGEVLLNRGSPSGIWGDLPEDIRKDLPFLGQDRGLEEMSEYSDDYRELDQNLFQPSSKQEPRGSAEYTDWGLLPGGGSEGGFNSSAGDGPAASAEKQQEDPELHKLNASAWTPAPKHSPERSLLLPLVTAPASGEELEKETFQLQEPPSKGSAREVLMPSRSPPLASLEFSPATMEESPVSTVMPWSPEHSISTLPASTVPTESPLSEQPASTPTAPRAVKELMVSAGDNLIITLPENEVELKASVVPVPPAETTYNYEWSLISHPEDYQGEIKQRHMETLNVSHLSLGHYAFKVAVSSENGFGEGFVNVTVKPAARVNLPPRAVVSPERQELTLPLTSAFIDGSQSTDDTKIVSYHWEEINGPFREEKTSAESPVLQLSNLLPGNYTFRLTVTDSDGATNSTTAALIVHSAVDHPPIADAGPNQTITLPQNSITLNGNQSSDDHQIVLYEWSLGPGSESKEVAMQGVETPYLHLSAMEEGDYTFQLIVTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELVFPVESTTLDGSQSSDDHGIVFYHWEHLRGPSAVEMENMDQAIATVSGLQVGTYHFRLTVKDQEGLSSTTTLTVAVKKENNSPPRAQAGGRHVLVLPNNSITLDGSRSTDDQGIVSYLWIRDGQSPAAGDVIGGSDHSAALQLTNLVEGVYTFRLRVADGQGASDTDTATVEVRPDPKKSGLVELILQVGVGQLEQQKDTLVRQLAVLLDVLDSDIKVQRIQAHSDLSTVIVFYVQSGPPFQVLKAAEVARNLHRRLSKEKADFLLFKVLRIDTAGCLLKCSGHGHCDPITKRCICSQLWMENLIQRYIRDGESNCEWSVFYVTILALTLVVLTGGVTWLCICCCKRRKRTKIRKKTKYTILDNMDDQERMELRPKYGIKHRSTEHNSSLMVSESEFDSDQDTIFSRERMERGNPKVSMNGSLRNGAAFSYCSKDR", "length": 1065, "header": "tr|A0A5G2QQH5-1|A0A5G2RC25_PIG Computationally mapped isoform of KIAA0319 OS=Sus scrofa OX=9823 GN=KIAA0319 PE=4 SV=1 CANONICAL=A0A5G2RC25-1" }, "locus": { "chromosome": "7", "start_pos": 19450747, "end_pos": 19386114, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071486.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071486.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066982.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066982.1" } ] } }, { "isoform_ac": "A0A5G2RC25-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25/entry#A0A5G2RC25-1", "sequence": { "sequence": "MAPPTGVLSSLLLLVTFTACACMQCSEGRTYSNAIISPNLETNKIMRVPQTTPVVDCTSACCDLASCDLAWWFEGRCYLVSCPHKENCQPKQMGSIRSYLTFVLRPAQRPAQLLDPGEVLLNRGSPSGIWGDLPEDIRKDLPFLGQDRGLEEMSEYSDDYRELDQNLFQPSSKQEPRGSAEYTDWGLLPGGGSEGGFNSSAGDGPAASAEKQQEDPELHKLNASAWTPAPKHSPERSLLLPLVTAPASGEELEKETFQLQEPPSKGSAREVLMPSRSPPLASLEFSPATMEESPVSTVMPWSPEHSISTLPASTVPTESPLSEQPASTPTAPRAVKELMVSAGDNLIITLPENEVELKASVVPVPPAETTYNYEWSLISHPEDYQGEIKQRHMETLNVSHLSLGHYAFKVAVSSENGFGEGFVNVTVKPAARVNLPPRAVVSPERQELTLPLTSAFIDGSQSTDDTKIVSYHWEEINGPFREEKTSAESPVLQLSNLLPGNYTFRLTVTDSDGATNSTTAALIVHSAVDHPPIADAGPNQTITLPQNSITLNGNQSSDDHQIVLYEWSLGPGSESKEVAMQGVETPYLHLSAMEEGDYTFQLIVTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELVFPVESTTLDGSQSSDDHGIVFYHWEHLRGPSAVEMENMDQAIATVSGLQVGTYHFRLTVKDQEGLSSTTTLTVAVKKENNSPPRAQAGGRHVLVLPNNSITLDGSRSTDDQGIVSYLWIRDGQSPAAGDVIGGSDHSAALQLTNLVEGVYTFRLRVADGQGASDTDTATVEVRPDPKKSGLVELILQVGVGQLEQQKDTLVRQLAVLLDVLDSDIKVQRIQAHSDLSTVIVFYVQSGPPFQVLKAAEVARNLHRRLSKEKADFLLFKVLRIDTAGCLLKCSGHGHCDPITKRCICSQLWMENLIQRYIRDGESNCEWSVFYVTILALTLVVLTGGVTWLCICCCKRRKRTKIRKKTKYTILDNMDDQERMELRPKYGIKHRSTEHNSSLMVSESEFDSDQDTIFSRERMERGNPKVSMNGSLRNGAAFSYCSKDR", "length": 1074, "header": "tr|A0A5G2RC25-1|A0A5G2RC25_PIG Isoform 1 of KIAA0319 OS=Sus scrofa OX=9823 GN=KIAA0319 PE=4 SV=1 CANONICAL=A0A5G2RC25-1" }, "locus": { "chromosome": "7", "start_pos": 19451561, "end_pos": 19386114, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087274.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087274.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071752.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071752.1" } ] } }, { "isoform_ac": "F1RUE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25/entry#F1RUE2-1", "sequence": { "sequence": "MAPPTGVLSSLLLLVTFTACACMQCSEGRTYSNAIISPNLETNKIMRVPQTTPVVDCTSACCDLASCDLAWWFEGRCYLVSCPHKENCQPKQMGSIRSYLTFVLRPAQRPAQLLDPGEVLLNRGSPSGIWGDLPEDIRKDLPFLGQDRGLEEMSEYSDDYRELDQNLFQPSSKQEPRGSAEYTDWGLLPGGGSEGGFNSSAGDGPAASAEKQQEDPELHKLNASAWTPAPKHSPERSLLLPLVTAPASGEELEKETFQLQEPPSKGSAREVLMPSRSPPLASLEFSPATMEESPVSTVMPWSPEHSISTLPASTVPTESPLSEQPASTPTAPRAVKELMVSAGDNLIITLPENEVELKASVVPVPPAETTYNYEWSLISHPEDYQGEIKQRHMETLNVSHLSLGHYAFKVAVSSENGFGEGFVNVTVKPAARVNLPPRAVVSPERQELTLPLTSAFIDGSQSTDDTKIVSYHWEEINGPFREEKTSAESPVLQLSNLLPGNYTFRLTVTDSDGATNSTTAALIVHSAVDHPPIADAGPNQTITLPQNSITLNGNQSSDDHQIVLYEWSLGPGSESKEVAMQGVETPYLHLSAMEEGDYTFQLIVTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELVFPVESTTLDGSQSSDDHGIVFYHWEHLRGPSAVEMENMDQAIATVSGLQVGTYHFRLTVKDQEGLSSTTTLTVAVKKENNSPPRAQAGGRHVLVLPNNSITLDGSRSTDDQGIVSYLWIRDGQSPAAGDVIGGSDHSAALQLTNLVEGVYTFRLRVADGQGASDTDTATVEVRPDPKKSGLVELILQVGVGQLEQQKDTLVRQLAVLLDVLDSDIKVQRIQAHSDLSTVIVFYVQSGPPFQVLKAAEVARNLHRRLSKEKADFLLFKVLRIDTAGCLLKCSGHGHCDPITKRCICSQLWMENLIQRYIRDGESNCGIKHRSTEHNSSLMVSESEFDSDQDTIFSRERMERGNPKVSMNGSLRNGAAFSYCSKDR", "length": 1013, "header": "tr|F1RUE2-1|A0A5G2RC25_PIG Computationally mapped isoform of KIAA0319 OS=Sus scrofa OX=9823 GN=KIAA0319 PE=4 SV=3 CANONICAL=A0A5G2RC25-1" }, "locus": { "chromosome": "7", "start_pos": 19451561, "end_pos": 19386114, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001187.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001187.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001162.4", "url": "https://www.ensembl.org/id/ENSSSCP00000001162.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQH5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQH5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-SSC-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25" } ], "pmid": "" }, { "name": "negative regulation of dendrite development", "id": "GO:2000171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000171", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC25", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1025, "end_pos": 1027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1058, "end_pos": 1060, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 516, "end_pos": 518, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 554, "end_pos": 556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 718, "end_pos": 720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RC25-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1074, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RC25-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC25" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RC25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25" }, { "id": "PS50986", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50986" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MANSC", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 99, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RC25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC25" }, { "id": "PS50093", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PKD", "eco_id": "ECO_0000259", "start_pos": 548, "end_pos": 621, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1025, "end_pos": 1027 }, { "start_pos": 1058, "end_pos": 1060 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 424, "end_pos": 426 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 516, "end_pos": 518 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 554, "end_pos": 556 }, { "start_pos": 718, "end_pos": 720 }, { "start_pos": 736, "end_pos": 738 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAE1-1", "uniprot_ac": "A0A5G2RAE1", "uniprot_id": "A0A5G2RAE1_PIG", "mass": { "chemical_mass": 117415.0, "monoisotopic_mass": 117415.0 }, "refseq": {}, "gene_names": [ { "name": "DDX46", "type": "recommended", "evidence": [ { "id": "A0A5G2RAE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" } ] } ], "protein_names": [ { "name": "Probable ATP-dependent RNA helicase DDX46", "type": "recommended", "evidence": [ { "id": "A0A5G2RAE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "A0A5G2RAE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1/entry#names_and_taxonomy" } ] }, { "name": "DEAD box protein 46", "type": "synonym", "evidence": [ { "id": "A0A5G2RAE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA branch-site adenosine, the nucleophile for the first step of splicing. Within the 17S U2 SnRNP complex, DDX46 plays essential roles during assembly of pre-spliceosome and proofreading of the branch site.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1#function" }, { "database": "UniProtKB", "id": "ARBA00049949", "url": "https://www.uniprot.org/uniprotkb/ARBA00049949#function" }, { "database": "UniProtKB", "id": "A0A5G2RK75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK75#function" }, { "database": "UniProtKB", "id": "I3LR20", "url": "https://www.uniprot.org/uniprotkb/I3LR20#function" }, { "database": "UniProtKB", "id": "A0A5G2QRA4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRA4#function" }, { "database": "UniProtKB", "id": "A0A8W4FIV2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIV2#function" }, { "database": "UniProtKB", "id": "A0A8W4FP69", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP69#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DDX46", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1", "locus": { "chromosome": "2", "start_pos": 137030430, "end_pos": 136972507, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026644", "url": "https://www.ensembl.org/id/ENSSSCG00000026644" } ] } } ], "crossref": [ { "id": "ENSSSCG00000026644", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026644", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17953", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17953", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QLPMKKW", "url": "https://omabrowser.org/oma/group/QLPMKKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR47958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QRA4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RK75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RK75-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFH4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIV2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FP69", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FP69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LR20", "url": "https://www.uniprot.org/uniprotkb/I3LR20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LR20-1", "url": "https://www.uniprot.org/uniprotkb/I3LR20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRDRRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKAENRSRSKEKTDSGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEVEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL", "length": 1032, "header": "tr|A0A5G2RAE1-1|A0A5G2RAE1_PIG Isoform 1 of Probable ATP-dependent RNA helicase DDX46 OS=Sus scrofa OX=9823 GN=DDX46 PE=1 SV=1 CANONICAL=A0A5G2RAE1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QRA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1/entry#A0A5G2QRA4-1", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRDRRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKAENRSRSKEKTDSGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEVEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLVTVYRPPLQGRQTRLCL", "length": 1033, "header": "tr|A0A5G2QRA4-1|A0A5G2RAE1_PIG Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX46 OS=Sus scrofa OX=9823 GN=DDX46 PE=1 SV=1 CANONICAL=A0A5G2RAE1-1" }, "locus": { "chromosome": "2", "start_pos": 137027040, "end_pos": 136972676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075469.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075469.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066582.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066582.1" } ] } }, { "isoform_ac": "A0A5G2R3Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1/entry#A0A5G2R3Y8-1", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEVEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGDAVR", "length": 438, "header": "tr|A0A5G2R3Y8-1|A0A5G2RAE1_PIG Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX46 OS=Sus scrofa OX=9823 GN=DDX46 PE=1 SV=1 CANONICAL=A0A5G2RAE1-1" }, "locus": { "chromosome": "2", "start_pos": 136996773, "end_pos": 136972676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070473.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070473.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071806.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071806.1" } ] } }, { "isoform_ac": "A0A5G2RAE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1/entry#A0A5G2RAE1-1", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRDRRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKAENRSRSKEKTDSGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEVEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL", "length": 1032, "header": "tr|A0A5G2RAE1-1|A0A5G2RAE1_PIG Isoform 1 of Probable ATP-dependent RNA helicase DDX46 OS=Sus scrofa OX=9823 GN=DDX46 PE=1 SV=1 CANONICAL=A0A5G2RAE1-1" }, "locus": { "chromosome": "2", "start_pos": 137027509, "end_pos": 136972676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088258.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088258.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067578.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067578.1" } ] } }, { "isoform_ac": "A0A5G2RK75-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1/entry#A0A5G2RK75-1", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRDRRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKAENRSRSKEKTDSGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNESGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL", "length": 995, "header": "tr|A0A5G2RK75-1|A0A5G2RK75_PIG Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX46 OS=Sus scrofa OX=9823 GN=DDX46 PE=1 SV=1 CANONICAL=A0A5G2RAE1-1" }, "locus": { "chromosome": "2", "start_pos": 137027509, "end_pos": 136972676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080115.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080115.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072440.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072440.1" } ] } }, { "isoform_ac": "A0A8W4FFH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1/entry#A0A8W4FFH4-1", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLSFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEVEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGKSGVGFFWFSFLFF", "length": 448, "header": "tr|A0A8W4FFH4-1|A0A5G2RAE1_PIG Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX46 OS=Sus scrofa OX=9823 GN=DDX46 PE=1 SV=1 CANONICAL=A0A5G2RAE1-1" }, "locus": { "chromosome": "2", "start_pos": 136995395, "end_pos": 136972676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101539.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101539.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078067.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078067.1" } ] } }, { "isoform_ac": "A0A8W4FIV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1/entry#A0A8W4FIV2-1", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRDRRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKAENRSRSKEKTDSGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLVTVYRPPLQGRQTRLCL", "length": 977, "header": "tr|A0A8W4FIV2-1|A0A5G2RAE1_PIG Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX46 OS=Sus scrofa OX=9823 GN=DDX46 PE=1 SV=1 CANONICAL=A0A5G2RAE1-1" }, "locus": { "chromosome": "2", "start_pos": 137027040, "end_pos": 136972676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099003.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099003.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079163.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079163.1" } ] } }, { "isoform_ac": "A0A8W4FMP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1/entry#A0A8W4FMP6-1", "sequence": { "sequence": "SRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKQEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEVEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSDKLRYCSFKKFYLL", "length": 414, "header": "tr|A0A8W4FMP6-1|A0A5G2RAE1_PIG Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX46 OS=Sus scrofa OX=9823 GN=DDX46 PE=1 SV=1 CANONICAL=A0A5G2RAE1-1" }, "locus": { "chromosome": "2", "start_pos": 136995752, "end_pos": 136976889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104335.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104335.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079585.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079585.1" } ] } }, { "isoform_ac": "A0A8W4FP69-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1/entry#A0A8W4FP69-1", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRDRRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKAENNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEVEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL", "length": 999, "header": "tr|A0A8W4FP69-1|A0A5G2RAE1_PIG Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX46 OS=Sus scrofa OX=9823 GN=DDX46 PE=1 SV=1 CANONICAL=A0A5G2RAE1-1" }, "locus": { "chromosome": "2", "start_pos": 137027509, "end_pos": 136972676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093455.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093455.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080100.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080100.1" } ] } }, { "isoform_ac": "I3LR20-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1/entry#I3LR20-1", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRDRRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKAENRSRSKEKTDSGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL", "length": 999, "header": "tr|I3LR20-1|A0A5G2RAE1_PIG Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX46 OS=Sus scrofa OX=9823 GN=DDX46 PE=1 SV=2 CANONICAL=A0A5G2RAE1-1" }, "locus": { "chromosome": "2", "start_pos": 137027509, "end_pos": 136972676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027801.3", "url": "https://www.ensembl.org/id/ENSSSCT00000027801.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026552.2", "url": "https://www.ensembl.org/id/ENSSSCP00000026552.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 260, "start_aa": "Thr", "end_pos": 260, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr260", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 842, "start_aa": "Thr", "end_pos": 842, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr842", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FFH4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFH4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-SSC-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" }, { "id": "R-SSC-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BSC0-1", "protein_name": "Probable ATP-dependent RNA helicase DDX46", "gene_name": "DDX46", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRKREDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRQRRSRSRERERSRERRRSRSRERRRSRSRSRGRRSRSPSPSKNRKTENRSRSKERTEGVEVSKEKKKEKDDKEEEKDKDASASTVATENFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDDEETAEGEKEGNEVEDEELDPLDAYMEEVKEEVKKFNMRSVKGGGGSEKKSGPTVTKVVTVVTTKKAVVETEKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMTQEEVNVYRLEMEGITVKGKGCPKPIKTWVQCGISMKILTALKKHGYEKPTPIQSQAIPAIMNGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRALEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANNGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQHVIVIEEENKFLKLLELLGHYQEKGSVIIFVDKQEHADGLLKDLMRASYPCLSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKQLMLVVNYSCPNHYEDYVHRAGRTGRAGNKGFAYTFITEDQARYAGDIIKALELSGNPIPADLEKLWADFKEQQKAEGKLIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDTAVDIDEQIESMFNSKKRVKDMGTPGSSNAPTPSAGNAEKLEIAKRLALRINAQKNLGAEAQVFVPFHFKDVMQQATNAILRGGTIQAPTVSAKTIAEQLAEKINAKLNYVPIEKQEEEKQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL", "length": 1043 }, "evidence": [ { "id": "A0A5G2RAE1", "url": "https://omabrowser.org/oma/group/A0A5G2RAE1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q553B1-1", "protein_name": "ATP-dependent RNA helicase ddx46", "gene_name": "helB1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDEYDKKRRLEHGGSDRSRSSNDNRNSHGSSGNNYRDDRKDDRYYRDDRSHYNNNNNNNNNNNNNNNNNNGNGYRDDRNYSSQNKYQNHHQQSPPQQQQQQQNSSYVPSQPPQQQTQTQQQPHIQAPPPAKPRKSRFDQAPETIPIQAPQQPPMISNQPIFKQQPMYQQPMYQQKQQQPQPPIFQQQQKQQQPPIFQHHQPPPIYQQPPVYQQQQQQQQPVFQQQQQQRVATEAIQFQQTPQQLAIEQERLKQERENEKKIEQANLEEEMKKRREKVEQWRKQKLEQELKASGSSNSGSTSSPPTTTTTTTKTTAATTTATTSPLTIPSQQQQTATTSPIKKKWSLEEEEETAQPLVNTNIEQKEIKLPPTANIPAAAATTTSATINTTTIKQSIEEDDDIDPLDAYMENLNKEANLNLKKSKTSQMIDDDEKLEEESEGEDDGKDKTIKKGKKEMLHTDHTSIKYAEFQKNFYIEVPVLANMTETEVLDFRSELGVKITGKDCPKPIQSWAQAGLTEKVHLLLKKFQYEKPTSIQAQTIPAIMNGRDLIGIARTGSGKTLAFLLPMFRHILAQPKSAPGEGMIALIMSPTRELALQIHVECKKFSKVLGLRTACVYGGASISEQIAELKRGADIVVCTPGRMIDILCANNRRITNLRRVTFLVLDEADRMFDMGFGPQINCIVDSIRPDRQTIMFSATFPPKVENVAKKILNKPLEIIAGGRSIVSSDIEQFVEVRPTETRFRRLIELLSIWYHKGQILIFTNRQETTDNLYRQLSNSQYQCLSLHGSKDQTDRDETISDFKNKVKTILIATPLASRGLDIKDLNLVVNFDCPDHLEDYVHRVGRTGRAGNRGTAYTFITPDEERFSSSIIKALEQSGSKVPDELRKLNDTYEKKRKEGKDVLLAPTGFTGRGHKFDAAEEDKKNIERKQQRKAYGIEEEEEEEDEDKEKAEKEKLAAASAEKEKQLLSEKEKLDPATTNTIVIPGVDGTIITPSSLLQTDPSVPVGQQAINQIFGISQVTSSEEAIKKLQLAAQLGMKGNIQKLNNQITPLNQTHFIEELEINDYSQQARWKVTHKDALLEITNFTNTTITTKGTFFPPNKIPAPGERKLYLYIEGPSDASVKNAKSDIKKILDEVQSTHQSTGKYSVF", "length": 1151 }, "evidence": [ { "id": "A0A5G2RAE1", "url": "https://omabrowser.org/oma/group/A0A5G2RAE1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q569Z5-1", "protein_name": "Probable ATP-dependent RNA helicase DDX46", "gene_name": "Ddx46", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGSKTKKTENRSRSKEKAEGGDSSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGTEMEDEELDPLDAYMEEVKEEVKKFNMRSVKGGAGNEKKSGPTVTKVVTVVTTKKAVVDADKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQEGGQSESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL", "length": 1032 }, "evidence": [ { "id": "A0A5G2RAE1", "url": "https://omabrowser.org/oma/group/A0A5G2RAE1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62780-1", "protein_name": "Probable ATP-dependent RNA helicase DDX46", "gene_name": "Ddx46", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGSKSKKAENRSRSKEKAEGGDSSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEDEELDPLDAYMEEVKEEVKKFNMRSVKGGAGNEKKSGPTVTKVVTVVTTKKAVVDADKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSAPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGPLLAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQEGGQSESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL", "length": 1032 }, "evidence": [ { "id": "A0A5G2RAE1", "url": "https://omabrowser.org/oma/group/A0A5G2RAE1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7L014-1", "protein_name": "Probable ATP-dependent RNA helicase DDX46", "gene_name": "DDX46", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL", "length": 1031 }, "evidence": [ { "id": "A0A5G2RAE1", "url": "https://omabrowser.org/oma/group/A0A5G2RAE1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8H0U8-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 42", "gene_name": "RH42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVEKSKYRSEDLDVVEEEADLKKSRRDRDRSNERKKDKGSEKRREKDRRKKRVKSSDSEDDYDRDDDEEREKRKEKERERRRRDKDRVKRRSERRKSSDSEDDVEEEDERDKRRVNEKERGHREHERDRGKDRKRDREREERKDKEREREKDRERREREREEREKERVKERERREREDGERDRREREKERGSRRNRERERSREVGNEESDDDVKRDLKRRRKEGGERKEKEREKSVGRSSRHEDSPKRKSVEDNGEKKEKKTREEELEDEQKKLDEEVEKRRRRVQEWQELKRKKEEAESESKGDADGNEPKAGKAWTLEGESDDEEGHPEEKSETEMDVDEETKPENDGDAKMVDLENETAATVSESGGDGAVDEEEIDPLDAFMNTMVLPEVEKFCNGAPPPAVNDGTLDSKMNGKESGDRPKKGFNKALGRIIQGEDSDSDYSEPKNDDDPSLDEDDEEFMKRVKKTKAEKLSLVDHSKIEYEPFRKNFYIEVKDISRMTQEEVNTYRKELELKVHGKDVPRPIKFWHQTGLTSKILDTMKKLNYEKPMPIQTQALPIIMSGRDCIGVAKTGSGKTLGFVLPMLRHIKDQPPVEAGDGPIGLVMAPTRELVQQIHSDIRKFSKPLGIRCVPVYGGSGVAQQISELKRGTEIVVCTPGRMIDILCTSSGKITNLRRVTFLVMDEADRMFDMGFEPQITRIIQNIRPERQTVLFSATFPRQVETLARKVLNKPVEIQVGGRSVVNKDITQLVEVRPESDRFLRLLELLGEWSEKGKILVFVQSQEKCDALYRDMIKSSYPCLSLHGGKDQTDRESTISDFKNDVCNLLIATSVAARGLDVKELELVVNFDAPNHYEDYVHRVGRTGRAGRKGCAVTFISEDDAKYAPDLVKALELSEQPVPDDLKALADGFMVKVKQGIEQAHGTGYGGSGFKFNEEEEEVRKAAKKAQAKEYGFEEDKSDSEDENDVVRKAGGGEISQQQATFAQIAAIAAAAKAAAAAPVSAPVTANQLLANGGGLAAMPGVLPVTVPTLPSEGAGRAAAMVAAMNLQHNLAKIQADAMPEHYEAELEINDFPQNARWKVTHKETLGPISEWTGAAITTRGQFYPTGRIPGPGERKLYLFIEGPSEKSVKHAKAELKRVLEDITNQAMSSLPGGASGRYSVL", "length": 1166 }, "evidence": [ { "id": "A0A5G2RAE1", "url": "https://omabrowser.org/oma/group/A0A5G2RAE1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAE1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 667, "end_pos": 669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 927, "end_pos": 929, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-SSC-9770141", "name": "Formation of the Spliceosomal C* complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-5688092", "R-SSC-5688093", "R-SSC-72073", "R-SSC-9769591", "R-SSC-9769593", "R-SSC-9769594", "R-SSC-9769596", "R-SSC-9769598", "R-SSC-9769599", "R-SSC-9769601" ], "output_participant_list": [ "R-SSC-72060", "R-SSC-8867898", "R-SSC-9770419", "R-SSC-9770425", "R-SSC-9770427", "R-SSC-9770428", "R-SSC-9770430" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9770141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770141" } ] }, { "id": "R-SSC-9770236", "name": "Formation of the Spliceosomal P complex and exon ligation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-9769588", "R-SSC-9769590", "R-SSC-9769602" ], "output_participant_list": [ "R-SSC-6791189", "R-SSC-8849139", "R-SSC-8952113", "R-SSC-9769562" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9770236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770236" } ] }, { "id": "R-SSC-9770847", "name": "Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-5688097", "R-SSC-8869310", "R-SSC-8869311", "R-SSC-9770846" ], "output_participant_list": [ "R-SSC-3900136", "R-SSC-6814858", "R-SSC-8865888", "R-SSC-8865956", "R-SSC-8952110", "R-SSC-9769561", "R-SSC-8867893", "R-SSC-9769592" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9770847", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770847" } ] }, { "id": "R-SSC-9794542", "name": "Formation of the Spliceosomal C complex containing intron lariat", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9794542", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9794542" } ] }, { "id": "R-SSC-9943567", "name": "CHD1:H3K4me3 interacts with post-initiation transcription complexes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9943567", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943567" } ] }, { "id": "R-SSC-9970141", "name": "Core CPA complex binds capped pre-mRNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9970141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970141" } ] }, { "id": "R-SSC-9970189", "name": "PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-72008" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9970189", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970189" } ] }, { "id": "R-SSC-9970190", "name": "PP1 dephosphorylates RNA Pol II", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9970190", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970190" } ] }, { "id": "R-SSC-9970191", "name": "RBBP6 activates CPSF complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9970191", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970191" } ] }, { "id": "R-SSC-9970318", "name": "PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9970318", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970318" } ] }, { "id": "R-SSC-9970320", "name": "PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9970320", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970320" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-3900136", "participant_name": "DDX5 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000043632", "database": "ENSEMBL", "url": "" }, { "id": "87226", "database": "VGNC", "url": "" }, { "id": "A0A287AHW6", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000032092", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000038465", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-5688092", "participant_name": "DHX8 [nucleoplasm]", "crossref": [ { "id": "F1S1H3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000017378", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000018412", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000018917", "database": "ENSEMBL", "url": "" }, { "id": "87298", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-5688093", "participant_name": "PRPF18 [nucleoplasm]", "crossref": [ { "id": "A0A4X1VY37", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000026354", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000027625", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000024330", "database": "ENSEMBL", "url": "" }, { "id": "NP_001231788.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-5688097", "participant_name": "DHX15 [nucleoplasm]", "crossref": [ { "id": "F1S5A8", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000008756", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000009333", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000009580", "database": "ENSEMBL", "url": "" }, { "id": "87286", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-6791189", "participant_name": "MTREX [nucleoplasm]", "crossref": [ { "id": "F1SLL6", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000017920", "database": "ENSEMBL", "url": "" }, { "id": "90470", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000018417", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000016911", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-6814858", "participant_name": "SRRT [nucleoplasm]", "crossref": [ { "id": "I3LI05", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000023704", "database": "ENSEMBL", "url": "" }, { "id": "93471", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000024767", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000024789", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-72008", "participant_name": "PABPN1 [nucleoplasm]", "crossref": [ { "id": "A0A287ASR3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000054284", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000047125", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000064723", "database": "ENSEMBL", "url": "" }, { "id": "NP_001230477.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-72060", "participant_name": "DHX38 [nucleoplasm]", "crossref": [ { "id": "F1S3A8", "database": "UniProt", "url": "" }, { "id": "XP_020949516.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000002966", "database": "ENSEMBL", "url": "" }, { "id": "87294", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000003045", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000002748", "database": "ENSEMBL", "url": "" }, { "id": "XP_020949515.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-72073", "participant_name": "SLU7 [nucleoplasm]", "crossref": [ { "id": "F1RR54", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000017033", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000018045", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000018545", "database": "ENSEMBL", "url": "" }, { "id": "XP_003134141.1", "database": "RefSeq", "url": "" }, { "id": "93214", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-8849139", "participant_name": "DDX39B [nucleoplasm]", "crossref": [ { "id": "XP_005665850.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000001487", "database": "ENSEMBL", "url": "" }, { "id": "NP_001005157.1", "database": "RefSeq", "url": "" }, { "id": "Q29024", "database": "UniProt", "url": "" }, { "id": "ENSSSCT00000001529", "database": "ENSEMBL", "url": "" }, { "id": "XP_005665851.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCG00000001400", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-8865888", "participant_name": "SRRM2 [nucleoplasm]", "crossref": [ { "id": "ENSSSCG00000023304", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000051053", "database": "ENSEMBL", "url": "" }, { "id": "93468", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000041895", "database": "ENSEMBL", "url": "" }, { "id": "A0A287ADD0", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-8865956", "participant_name": "CWC22 [nucleoplasm]", "crossref": [ { "id": "XP_003133562.2", "database": "RefSeq", "url": "" }, { "id": "XP_013839769.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000016961", "database": "ENSEMBL", "url": "" }, { "id": "A0A4X1TWU8", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000016008", "database": "ENSEMBL", "url": "" }, { "id": "XP_005672046.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCT00000017430", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-8867893", "participant_name": "PPWD1 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000017953", "database": "ENSEMBL", "url": "" }, { "id": "NP_001231350.1", "database": "RefSeq", "url": "" }, { "id": "F1SKT8", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000016945", "database": "ENSEMBL", "url": "" }, { "id": "91766", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000018453", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-8867898", "participant_name": "CWC25 [nucleoplasm]", "crossref": [ { "id": "ENSSSCT00000053706", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000021478", "database": "ENSEMBL", "url": "" }, { "id": "87096", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000032040", "database": "ENSEMBL", "url": "" }, { "id": "A0A286ZKR9", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-8869310", "participant_name": "TFIP11 [nucleoplasm]", "crossref": [ { "id": "Q06AK6", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000009962", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000010632", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000010917", "database": "ENSEMBL", "url": "" }, { "id": "XP_020927865.1", "database": "RefSeq", "url": "" }, { "id": "XP_020927864.1", "database": "RefSeq", "url": "" }, { "id": "NP_001070682.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-8869311", "participant_name": "GCFC2 [nucleoplasm]", "crossref": [ { "id": "I3LDF5", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000021287", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000022086", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000031635", "database": "ENSEMBL", "url": "" }, { "id": "XP_020942970.1", "database": "RefSeq", "url": "" }, { "id": "88382", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-8952110", "participant_name": "PPIL3 [nucleoplasm]", "crossref": [ { "id": "XP_013839835.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCT00000017525", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000016096", "database": "ENSEMBL", "url": "" }, { "id": "XP_001926016.1", "database": "RefSeq", "url": "" }, { "id": "XP_005672124.1", "database": "RefSeq", "url": "" }, { "id": "103073", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000017053", "database": "ENSEMBL", "url": "" }, { "id": "XP_001925960.1", "database": "RefSeq", "url": "" }, { "id": "F2Z5T7", "database": "UniProt", "url": "" }, { "id": "XP_005672126.1", "database": "RefSeq", "url": "" }, { "id": "XP_005672125.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-8952113", "participant_name": "PPIL4 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000023314", "database": "ENSEMBL", "url": "" }, { "id": "91699", "database": "VGNC", "url": "" }, { "id": "I3LGX0", "database": "UniProt", "url": "" }, { "id": "ENSSSCT00000024741", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000028867", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769561", "participant_name": "CCDC12 [nucleoplasm]", "crossref": [ { "id": "A0A8W4FDT6", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000077421", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000093297", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000011329", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769562", "participant_name": "PPIL2 [nucleoplasm]", "crossref": [ { "id": "ENSSSCG00000010083", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000056926", "database": "ENSEMBL", "url": "" }, { "id": "91698", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000040807", "database": "ENSEMBL", "url": "" }, { "id": "A0A287AAH2", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-9769588", "participant_name": "C1H9orf78 [nucleoplasm]", "crossref": [ { "id": "F1RQE0", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000030426", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000022510", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000024953", "database": "ENSEMBL", "url": "" }, { "id": "85975", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769590", "participant_name": "LENG1 [nucleoplasm]", "crossref": [ { "id": "F1RNH2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000003265", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000003541", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000003626", "database": "ENSEMBL", "url": "" }, { "id": "XP_003127463.2", "database": "RefSeq", "url": "" }, { "id": "89680", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769591", "participant_name": "CACTIN [nucleoplasm]", "crossref": [ { "id": "A0A287BJU2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000032085", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000056347", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000037250", "database": "ENSEMBL", "url": "" }, { "id": "86131", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769592", "participant_name": "PPIG [nucleoplasm]", "crossref": [ { "id": "XP_005671972.1", "database": "RefSeq", "url": "" }, { "id": "XP_020931930.1", "database": "RefSeq", "url": "" }, { "id": "XP_005671971.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000047092", "database": "ENSEMBL", "url": "" }, { "id": "XP_020931929.1", "database": "RefSeq", "url": "" }, { "id": "A0A4X1VJX6", "database": "UniProt", "url": "" }, { "id": "XP_020931927.1", "database": "RefSeq", "url": "" }, { "id": "XP_005671973.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCG00000031123", "database": "ENSEMBL", "url": "" }, { "id": "XP_001926896.1", "database": "RefSeq", "url": "" }, { "id": "XP_020931928.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCT00000066047", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769593", "participant_name": "SDE2 [nucleoplasm]", "crossref": [ { "id": "A0A8W4FFC9", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000010858", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000078134", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000092221", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769594", "participant_name": "PRKRIP1 [nucleoplasm]", "crossref": [ { "id": "A0A5G2QNT3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000042324", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000065720", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000069793", "database": "ENSEMBL", "url": "" }, { "id": "XP_005661993.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9769596", "participant_name": "STEEP1 [nucleoplasm]", "crossref": [ { "id": "F2Z566", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000012622", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000013420", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000013801", "database": "ENSEMBL", "url": "" }, { "id": "87113", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769598", "participant_name": "FAM32A [nucleoplasm]", "crossref": [ { "id": "A0A4X1UYF2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000013855", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000014729", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000015134", "database": "ENSEMBL", "url": "" }, { "id": "NP_001230816.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9769599", "participant_name": "FAM50A [nucleoplasm]", "crossref": [ { "id": "A0A5G2QKU3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000025303", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000064609", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000089389", "database": "ENSEMBL", "url": "" }, { "id": "87972", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769601", "participant_name": "DDX41 [nucleoplasm]", "crossref": [ { "id": "A0A287AWY6", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000032642", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000048662", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000059325", "database": "ENSEMBL", "url": "" }, { "id": "87221", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769602", "participant_name": "NKAP [nucleoplasm]", "crossref": [ { "id": "A0A5G2RJX5", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000012613", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000072270", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000085170", "database": "ENSEMBL", "url": "" }, { "id": "90756", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9770419", "participant_name": "GPATCH1 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000003085", "database": "ENSEMBL", "url": "" }, { "id": "XP_020949947.1", "database": "RefSeq", "url": "" }, { "id": "F1RNW7", "database": "UniProt", "url": "" }, { "id": "88573", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000003166", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000002865", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9770425", "participant_name": "WDR70 [nucleoplasm]", "crossref": [ { "id": "ENSSSCT00000018344", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000016846", "database": "ENSEMBL", "url": "" }, { "id": "94937", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000017848", "database": "ENSEMBL", "url": "" }, { "id": "F1SN94", "database": "UniProt", "url": "" }, { "id": "XP_020932620.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9770427", "participant_name": "DHX35 [nucleoplasm]", "crossref": [ { "id": "95678", "database": "VGNC", "url": "" }, { "id": "ENSSSCG00000007352", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000063112", "database": "ENSEMBL", "url": "" }, { "id": "A0A287B5Q0", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000051779", "database": "ENSEMBL", "url": "" }, { "id": "XP_001929057.3", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9770428", "participant_name": "NSRP1 [nucleoplasm]", "crossref": [ { "id": "A0A8D1TUT0", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000018853", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000019367", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000017795", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9770430", "participant_name": "YJU2 [nucleoplasm]", "crossref": [ { "id": "ENSSSCG00000013499", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000072636", "database": "ENSEMBL", "url": "" }, { "id": "95033", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000068755", "database": "ENSEMBL", "url": "" }, { "id": "A0A5G2QX80", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-9770846", "participant_name": "CWF19L2 [nucleoplasm]", "crossref": [ { "id": "A0A5K1V0N0", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000028201", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000028057", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000026318", "database": "ENSEMBL", "url": "" }, { "id": "96726", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" }, { "id": "PS51195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DEAD-box RNA helicase Q", "eco_id": "ECO_0000259", "start_pos": 372, "end_pos": 400, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RAE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 403, "end_pos": 581, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RAE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 592, "end_pos": 753, "start_aa": "Asp", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RAE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAE1" }, { "id": "PRU00552", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00552" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Q motif", "eco_id": "ECO_0000256", "start_pos": 372, "end_pos": 400, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 260, 842 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 116, "end_pos": 118 }, { "start_pos": 667, "end_pos": 669 }, { "start_pos": 693, "end_pos": 695 }, { "start_pos": 927, "end_pos": 929 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8T0-1", "uniprot_ac": "A0A5G2R8T0", "uniprot_id": "A0A5G2R8T0_PIG", "mass": { "chemical_mass": 102063.0, "monoisotopic_mass": 102063.0 }, "refseq": { "ac": "XP_020924295", "name": "probable leucine--tRNA ligase, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924295" }, "gene_names": [ { "name": "LARS2", "type": "recommended", "evidence": [ { "id": "A0A5G2R8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0" } ] }, { "name": "LARS2", "type": "synonym", "evidence": [ { "id": "XP_020924295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924295" } ] } ], "protein_names": [ { "name": "leucine--tRNA ligase", "type": "recommended", "evidence": [ { "id": "A0A5G2R8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.4", "type": "synonym", "evidence": [ { "id": "A0A5G2R8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0/entry#names_and_taxonomy" } ] }, { "name": "Leucyl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "A0A5G2R8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0/entry#names_and_taxonomy" } ] }, { "name": "probable leucine--tRNA ligase, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_020924295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924295" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8T0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LARS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0", "locus": { "chromosome": "13", "start_pos": 28692327, "end_pos": 28524796, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011312", "url": "https://www.ensembl.org/id/ENSSSCG00000011312" } ] } } ], "crossref": [ { "id": "A0A5G2R8T0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8T0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011312", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011312", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00812", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00812", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07958", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07958", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513625", "url": "https://www.ncbi.nlm.nih.gov/gene/100513625", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513625", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513625", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GIEHACM", "url": "https://omabrowser.org/oma/group/GIEHACM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R8T0", "url": "https://www.orthodb.org/?gene=A0A5G2R8T0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43740", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43740", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43740:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43740:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08264", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08264", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13603", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13603", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020924295", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924295", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11688", "url": "https://www.rhea-db.org/rhea/11688", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QCW2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QCW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8T0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG95-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SNZ5", "url": "https://www.uniprot.org/uniprotkb/F1SNZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SNZ5-1", "url": "https://www.uniprot.org/uniprotkb/F1SNZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LI93", "url": "https://www.uniprot.org/uniprotkb/I3LI93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LI93-1", "url": "https://www.uniprot.org/uniprotkb/I3LI93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LLA2", "url": "https://www.uniprot.org/uniprotkb/I3LLA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LLA2-1", "url": "https://www.uniprot.org/uniprotkb/I3LLA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPWQRLRFYAFLLQRQLNGGPDVINWGRGVIPGCSRGIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIRHMRKQLDRLGLCFSWDREITTCLPDYYRWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDTLADLPEWYGIKGMQAHWIGDCVGCHLDFALKVDGQVTEEELSAYTATPEAIYGTSHVAISPSHRLLHGCSSLKEVFQKALVPGRDCLTPVMAVNMLTQQEVPVIILAKADFEGSLDAKIGIPSTSSEDTVLAQSLGLSYSEVIETSPDGTERLSNSAEFTGMNRLDAFLALTQKARRKRVGGDVTSDKLKDWLISRQRYWGTPIPMVHCPACGPVPVPLDDLPVTLPSITSFTGKGGSPLASASEWVNCSCPRCKGAATRETDTMDTFVDSAWYYFRYTDPQNTQSPFSTALADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHVKTREKLEVTWEKMSKSKHNGVDPEDVVEQYGIDTIRLYLLFAAPPEKDILWDVKTDALPGVLRWQQRLWALATRFIEARISEKVPRPQLLSNKEKAEAKKLWEYKNSVISQVTAHFTEDLSLNSVISHLMGLSSALSQASQRVVLHSPEFEDALCALMVMAAPMAPHITSELWAGLALVPRKLCPHYAWDADVLLQAWPAVDPQFLQQPDVVQMAVLINNKACGKIPVPQQVAQDQDKVYELVLQSELGIKLLQGRSIKKAFLSPRTALINFLVQE", "length": 902, "header": "tr|A0A5G2R8T0-1|A0A5G2R8T0_PIG Isoform 1 of leucine--tRNA ligase OS=Sus scrofa OX=9823 GN=LARS2 PE=3 SV=1 CANONICAL=A0A5G2R8T0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QCW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0/entry#A0A5G2QCW2-1", "sequence": { "sequence": "MAPWQRLRFYAFLLQRQLNGGPDVINWGRGVIPGCSRGIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQEITTCLPDYYRWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDTLADLPEWYGIKGMQAHWIGDCVGCHLDFALKVDGQVTEEELSAYTATPEAIYGTSHVAISPSHRLLHGCSSLKEVFQKALVPGRDCLTPVMAVNMLTQQEVPVIILAKADFEGSLDAKIGIPSTSSEDTVLAQSLGLSYSEVIETSPDGTERLSNSAEFTGMNRLDAFLALTQKARRKRVGGDVTSDKLKDWLISRQRYWGTPIPMVHCPACGPVPVPLDDLPVTLPSITSFTGKGGSPLASASEWVNCSCPRCKGAATRETDTMDTFVDSAWYYFRYTDPQNTQSPFSTALADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHVKTREKLEVTWEKMSKSKHNGVDPEDVVEQYGIDTIRLYLLFAAPPEKDILWDVKTDALPGVLRWQQRLWALATRFIEARISEKVPRPQLLSNKEKAEAKKLWEYKNSVISQVTAHFTEDLSLNSVISHLMGLSSALSQASQRVVLHSPEFEDALCALMVMAAPMAPHITSELWAGLALVPRKLCPHYAWDADVLLQAWPAVDPQFLQQPDVVQMAVLINNKACGKIPVPQQVAQDQDKVYELVLQSELGIKLLQGRSIKKAFLSPRTALINFLVQE", "length": 851, "header": "tr|A0A5G2QCW2-1|A0A5G2QCW2_PIG Computationally mapped isoform of leucine--tRNA ligase OS=Sus scrofa OX=9823 GN=LARS2 PE=3 SV=1 CANONICAL=A0A5G2R8T0-1" }, "locus": { "chromosome": "13", "start_pos": 28691144, "end_pos": 28528989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076874.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076874.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061960.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061960.1" } ] } }, { "isoform_ac": "A0A5G2QTJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0/entry#A0A5G2QTJ3-1", "sequence": { "sequence": "MAPWQRLRFYAFLLQRQLNGGPDVINWGRGVIPGCSRGIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIRHMRKQLDRLGLCFSWDREITTCLPDYYRWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDTLADLPEWYGIKGMQAHWIGDCVGCHLDFALKVDGQVTEEELSAYTATPEAIYGTSHVAISPSHRLLHGCSSLKEVFQKALVPGRDCLTPVMAVNMLTQQEVPVIILAKADFEGSLDAKIGIPSTSSEDTVLAQSLGLSYSEVIETSPDGTERLSNSAEFTGMNRLDAFLALTQKARRKRVGGDVTSDKLKDWLISRQRYWGTPIPMVHCPACGPVPVPLDDLPVTLPSITSFTGKGGSPLASASEWVNCSCPRCKGAATRETDTMDTFVDSAWYYFRYTDPQNTQSPFSTALADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHVKTREKLEVTWEKMSKSKHNGVDPEDVVEQYGIDTIRLYLLFAAPPEKDILWDVKTDALPGVLRWQQRLWALATRFIEARISEKVPRPQLLSNKEKAEAKKLWEYKNSVISQVTAHFTEDLSLNSVISHLMGLSSALSQASQRVVLHSPEFEDALCALMVMAAPMAPHITSELWADALGHGVQHLASALRISLRKWEGSEQMPCRRTCWLCGLVLQASCSEVSCDSCGCCGGA", "length": 858, "header": "tr|A0A5G2QTJ3-1|A0A5G2R8T0_PIG Computationally mapped isoform of leucine--tRNA ligase OS=Sus scrofa OX=9823 GN=LARS2 PE=3 SV=1 CANONICAL=A0A5G2R8T0-1" }, "locus": { "chromosome": "13", "start_pos": 28673722, "end_pos": 28528989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083354.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083354.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068246.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068246.1" } ] } }, { "isoform_ac": "A0A5G2R8T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0/entry#A0A5G2R8T0-1", "sequence": { "sequence": "MAPWQRLRFYAFLLQRQLNGGPDVINWGRGVIPGCSRGIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIRHMRKQLDRLGLCFSWDREITTCLPDYYRWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDTLADLPEWYGIKGMQAHWIGDCVGCHLDFALKVDGQVTEEELSAYTATPEAIYGTSHVAISPSHRLLHGCSSLKEVFQKALVPGRDCLTPVMAVNMLTQQEVPVIILAKADFEGSLDAKIGIPSTSSEDTVLAQSLGLSYSEVIETSPDGTERLSNSAEFTGMNRLDAFLALTQKARRKRVGGDVTSDKLKDWLISRQRYWGTPIPMVHCPACGPVPVPLDDLPVTLPSITSFTGKGGSPLASASEWVNCSCPRCKGAATRETDTMDTFVDSAWYYFRYTDPQNTQSPFSTALADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHVKTREKLEVTWEKMSKSKHNGVDPEDVVEQYGIDTIRLYLLFAAPPEKDILWDVKTDALPGVLRWQQRLWALATRFIEARISEKVPRPQLLSNKEKAEAKKLWEYKNSVISQVTAHFTEDLSLNSVISHLMGLSSALSQASQRVVLHSPEFEDALCALMVMAAPMAPHITSELWAGLALVPRKLCPHYAWDADVLLQAWPAVDPQFLQQPDVVQMAVLINNKACGKIPVPQQVAQDQDKVYELVLQSELGIKLLQGRSIKKAFLSPRTALINFLVQE", "length": 902, "header": "tr|A0A5G2R8T0-1|A0A5G2R8T0_PIG Isoform 1 of leucine--tRNA ligase OS=Sus scrofa OX=9823 GN=LARS2 PE=3 SV=1 CANONICAL=A0A5G2R8T0-1" }, "locus": { "chromosome": "13", "start_pos": 28691144, "end_pos": 28528989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085575.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085575.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073491.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073491.1" } ] } }, { "isoform_ac": "A0A5G2RG95-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0/entry#A0A5G2RG95-1", "sequence": { "sequence": "MAPWQRLRFYAFLLQRQLNGGPDVINWGRGVIPGCSRGIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADVINPMGWDAFGLPAENAAIERNLHPESWTQSNIRHMRKQLDRLGLCFSWDREITTCLPDYYRWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDTLADLPEWYGIKGMQAHWIGDCVGCHLDFALKVDGQVTEEELSAYTATPEAIYGTSHVAISPSHRLLHGCSSLKEVFQKALVPGRDCLTPVMAVNMLTQQEVPVIILAKADFEGSLDAKIGIPSTSSEDTVLAQSLGLSYSEVIETSPDGTERLSNSAEFTGMNRLDAFLALTQKARRKRVGGDVTSDKLKDWLISRQRYWGTPIPMVHCPACGPVPVPLDDLPVTLPSITSFTGKGGSPLASASEWVNCSCPRCKGAATRETDTMDTFVDSAWYYFRYTDPQNTQSPFSTALADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHVKTREKLEVTWEKMSKSKHNGVDPEDVVEQYGIDTIRLYLLFAAPPEKDILWDVKTDALPGVLRWQQRLWALATRFIEARISEKVPRPQLLSNKEKAEAKKLWEYKNSVISQVTAHFTEDLSLNSVISHLMGLSSALSQASQRVVLHSPEFEDALCALMVMAAPMAPHITSELWAGLALVPRKLCPHYAWDADVLLQAWPAVDPQFLQQPDVVQMAVLINNKACGKIPVPQQVAQDQDKVYELVLQSELGIKLLQGRSIKKAFLSPRTALINFLVQE", "length": 859, "header": "tr|A0A5G2RG95-1|A0A5G2RG95_PIG Computationally mapped isoform of leucine--tRNA ligase OS=Sus scrofa OX=9823 GN=LARS2 PE=3 SV=1 CANONICAL=A0A5G2R8T0-1" }, "locus": { "chromosome": "13", "start_pos": 28691144, "end_pos": 28528989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078345.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078345.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073988.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073988.1" } ] } }, { "isoform_ac": "F1SNZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0/entry#F1SNZ5-1", "sequence": { "sequence": "MAPWQRLRFYAFLLQRQLNGGPDVINWGRGVIPGCSRGIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIRHMRKQLDRLGLCFSWDRALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDTLADLPEWYGIKGMQAHWIGDCVGCHLDFALKVDGQVTEEELSAYTATPEAIYGTSHVAISPSHRLLHGCSSLKEVFQKALVPGRDCLTPVMAVNMLTQQEVPVIILAKADFEGSLDAKIGIPSTSSEDTVLAQSLGLSYSEVIETSPDGTERLSNSAEFTGMNRLDAFLALTQKARRKRVGGDVTSDKLKDWLISRQRYWGTPIPMVHCPACGPVPVPLDDLPVTLPSITSFTGKGGSPLASASEWVNCSCPRCKGAATRETDTMDTFVDSAWYYFRYTDPQNTQSPFSTALADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHVKTREKLEVTWEKMSKSKHNGVDPEDVVEQYGIDTIRLYLLFAAPPEKDILWDVKTDALPGVLRWQQRLWALATRFIEARISEKVPRPQLLSNKEKAEAKKLWEYKNSVISQVTAHFTEDLSLNSVISHLMGLSSALSQASQRVVLHSPEFEDALCALMVMAAPMAPHITSELWAGLALVPRKLCPHYAWDADVLLQAWPAVDPQFLQQPDVVQMAVLINNKACGKIPVPQQVAQDQDKVYELVLQSELGIKLLQGRSIKKAFLSPRTALINFLVQE", "length": 872, "header": "tr|F1SNZ5-1|F1SNZ5_PIG Computationally mapped isoform of leucine--tRNA ligase OS=Sus scrofa OX=9823 GN=LARS2 PE=3 SV=3 CANONICAL=A0A5G2R8T0-1" }, "locus": { "chromosome": "13", "start_pos": 28691144, "end_pos": 28528989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012384.3", "url": "https://www.ensembl.org/id/ENSSSCT00000012384.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012060.3", "url": "https://www.ensembl.org/id/ENSSSCP00000012060.3" } ] } }, { "isoform_ac": "I3LI93-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0/entry#I3LI93-1", "sequence": { "sequence": "MAPWQRLRFYAFLLQRQLNGGPDVINWGRGVIPGCSRGIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIRHMRKQLDRLGLCFSWDREITTCLPDYYRWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDTLADLPEWYGIKGMQAHWIGDCVGCHLDFALKVDGQVTEEELSAYTATPEAIYGTSHVAISPSHRLLHGCSSLKEVFQKALVPGRGIPSTSSEDTVLAQSLGLSYSEVIETSPDGTERLSNSAEFTGMNRLDAFLALTQKARRKRVGGDVTSDKLKDWLISRQRYWGTPIPMVHCPACGPVPVPLDDLPVTLPSITSFTGKGGSPLASASEWVNCSCPRCKGAATRETDTMDTFVDSAWYYFRYTDPQNTQSPFSTALADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHVKTREKLEVTWEKMSKSKHNGVDPEDVVEQYGIDTIRLYLLFAAPPEKDILWDVKTDALPGVLRWQQRLWALATRFIEARISEKVPRPQLLSNKEKAEAKKLWEYKNSVISQVTAHFTEDLSLNSVISHLMGLSSALSQASQRVVLHSPEFEDALCALMVMAAPMAPHITSELWAGLALVPRKLCPHYAWDADVLLQAWPAVDPQFLQQPDVVQMAVLINNKACGKIPVPQQVAQDQDKVYELVLQSELGIKLLQGRSIKKAFLSPRTALINFLVQE", "length": 867, "header": "tr|I3LI93-1|A0A5G2R8T0_PIG Computationally mapped isoform of leucine--tRNA ligase OS=Sus scrofa OX=9823 GN=LARS2 PE=3 SV=2 CANONICAL=A0A5G2R8T0-1" }, "locus": { "chromosome": "13", "start_pos": 28691144, "end_pos": 28528989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024438.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024438.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023793.2", "url": "https://www.ensembl.org/id/ENSSSCP00000023793.2" } ] } }, { "isoform_ac": "I3LLA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0/entry#I3LLA2-1", "sequence": { "sequence": "MAPWQRLRFYAFLLQRQLNGGPDVINWGRGVIPGCSRGIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIRHMRKQLDRLGLCFSWDREITTCLPDYYRWTQYLFIKLYEAGLAYQKEAMQDTLADLPEWYGIKGMQAHWIGDCVGCHLDFALKVDGQVTEEELSAYTATPEAIYGTSHVAISPSHRLLHGCSSLKEVFQKALVPGRDCLTPVMAVNMLTQQEVPVIILAKADFEGSLDAKIGIPSTSSEDTVLAQSLGLSYSEVIETSPDGTERLSNSAEFTGMNRLDAFLALTQKARRKRVGGDVTSDKLKDWLISRQRYWGTPIPMVHCPACGPVPVPLDDLPVTLPSITSFTGKGGSPLASASEWVNCSCPRCKGAATRETDTMDTFVDSAWYYFRYTDPQNTQSPFSTALADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHVKTREKLEVTWEKMSKSKHNGVDPEDVVEQYGIDTIRLYLLFAAPPEKDILWDVKTDALPGVLRWQQRLWALATRFIEARISEKVPRPQLLSNKEKAEAKKLWEYKNSVISQVTAHFTEDLSLNSVISHLMGLSSALSQASQRVVLHSPEFEDALCALMVMAAPMAPHITSELWAGLALVPRKLCPHYAWDADVLLQAWPAVDPQFLQQPDVVQMAVLINNKACGKIPVPQQVAQDQDKVYELVLQSELGIKLLQGRSIKKAFLSPRTALINFLVQE", "length": 854, "header": "tr|I3LLA2-1|A0A5G2R8T0_PIG Computationally mapped isoform of leucine--tRNA ligase OS=Sus scrofa OX=9823 GN=LARS2 PE=3 SV=3 CANONICAL=A0A5G2R8T0-1" }, "locus": { "chromosome": "13", "start_pos": 28691144, "end_pos": 28528989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024122.3", "url": "https://www.ensembl.org/id/ENSSSCT00000024122.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024869.3", "url": "https://www.ensembl.org/id/ENSSSCP00000024869.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LI93", "url": "https://www.uniprot.org/uniprotkb/I3LI93" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513625", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513625", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZU78-1", "protein_name": "leucine--tRNA ligase", "gene_name": "Lars2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASACQRLSFCVSPLKRQLVSGLPVILWERIIPGCSRSIYSATGKWTKEYTLQTRKDVEKWWHQQIKVQASKISEEDKLKPKFYLLSMFPYPSGKLHMGHVRVYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEYGCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALADLPEWYGIKEMQAHWIGDCVGCHLDFTLKVDGQDTGEKLTAYTATPEAIYGISHVAISPSHGLLHGCSSLKTALQKALVPGRDCLTPVMAVNMLTLQEVPVVIMAKPDLEGSLDSKIGIPSTSSEDTRLAQALGLPYSEVIETSPDGTERLSGSAEFTGMTRQDAFVALTRKARGMRVGGHVTSNKLKDWLVSRQRYWGTPIPIVHCPACGPVPVPLQDLPVTLPSITSLTGRGGSPLASALEWVNCSCPRCKGSAKRETDTMDTFVDSAWYYFRYTDPHNTHSPFSSALADFWMPVDLYIGGKEHAVMHLFYARFFSHFCHRQKMVKHREPFHKLLAQGLIKGQTFHLLSGQCLKREDIDFTGPTPVCAKTKERLEVTWEKMSKSKHNGVDPEEIVAQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWSLTTRFIEARTSGTAPQPQLLNNKEKAKARSLWEYKNAVITQVTTHFTEDFALNSVVSQLMGLSGALSQASQRLVLHSPEFEDALCALLVMAAPLAPHITSELWAGLALVPSKLCDRYAWDAGVMLQAWPTVDSQFLQKPDMVQMAVLINNKACGKIPVPQHVAQDQDKVHEFVLQSELGIKLLQGRSIRKAFLSPRTALINFLVKE", "length": 902 }, "evidence": [ { "id": "A0A5G2R8T0", "url": "https://omabrowser.org/oma/group/A0A5G2R8T0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YV38-1", "protein_name": "leucine--tRNA ligase", "gene_name": "LARS2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDTVALRMQSVCRRFGACSTCLNRQLNGFLGLRNRTPLPSHACIRTIYSETGRWEKNYGQETRRRVENWWFPRIKEQFCRISETDKSRPKFYVLSMFPYPSGKLHMGHVRVYTISDTVARFQKMRGMQVLNPMGWDAFGLPAENAAIEHGLHPASWTQSNIQHMREQFDALGLSFTWEREITTCLPEYYKWTQYLFLKLFESGMVYQKEALVNWDPVDQTVLANEQVDDNGCSWRSGAKVEQKYLKQWFIKTTAYAKAMFDALSDLPEWYGIKEMQANWIGDCVGCSLDFLLKVNGEVTGEKLAAYTYTPEAIYGASHLYILPSHRLLHGNSSLKEVFQREFIPGKDSLTSVTAVNLLTNQEIPVVISGKTSFENYLDTKIGIPCTSAEDAAVAKNLNISFTEVIEKLPNGLEKVINSGEFTGMTRQDALKALTQQAKNKGIGGDLMSDKLRDWLISRQRYWGTPIPVIHCRTCGTVPVPYEDLPVVLPNVTTFTGKGASPLETVPEWVNCACPRCKAEARREIDTMDTFVDSAWYYLRYTDPHNTQRPFNRDLADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDLKMTKHKEPFHKLLVQGLIKNQTFRLRTTGQYLKREEIDLTGTEPVHLKSGEKVQVTWEKMSKSKHNGIDPEELMKEYGIDTIRLYILFAAPPEQDILWDTKTDAMPGVQRWQTRLWTLVTKLIEARTSETMPNPEVLSKKQKAEARRIWEQKNLVISEVTEYFTKDHLFNAAISRLMSLSNVLHQASWPLVLHSAEYEDALATLCVMVAPMAPHIASEMWKGLAHIENKLCTHHNWGADVLHQSWPKVDPEYLQPPDVVEMSVLINNKACGKVFVPQQAARNFAEVHELVLQSELGAKHLQGRTIKKAFLSPRTALINFLVQERKR", "length": 914 }, "evidence": [ { "id": "A0A5G2R8T0", "url": "https://omabrowser.org/oma/group/A0A5G2R8T0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1B768-1", "protein_name": "leucine--tRNA ligase", "gene_name": "LARS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPSWQRLGLYACLLKRQLNDGPDVIKWGRRVIPGWSRGIYSATGEWTKEYTLQTRKDVEKWWHQRIKDQALTVSEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIRHMRKQLDQLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAGLPEWYGIKGMQAHWIGNCVGCHLDFMLKVDGQVTGEKLSAYTATPEAVYGASHVAISPSHRLLHGHSPLKETFRKALVPGQDCLTPVTAVNMLTQQEVPVIILAKDDLEGSLDAKIGIPSTSLEDSALAQTLGLSYSEVIEETPDGTERLRGSAEFTGMKRQDAFLALTQKARRERVGGDVTSDKLKDWLVSRQRYWGTPIPMVHCPACGPVPVPLEDLPVTLPSITPLTGRGGSPLASASEWVNCSCPRCKGAATRETDTMDTFVDSAWYYFRYTDPQNTQSPFSAALADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLRREEVDLTGSDPVHANTGEKLEVSWEKMSKSKHNGVEPEDVVEQYGRDTVRLYVLFAAPPEKDILWDVKTDALPGVLRWQQRLWALVTRFIEARTSGKAPRPQLLSDKDKAEARRLWEYKNSVISQVTAHFTEDFSLNSAISQLMGLSSALSQASQRVVLHSPEFEDALCALMVMAAPMAPHITSELWAGLALVPQKLCAHYAWNTSVLLQAWPTVDPQFLQQPEVVQMAVLINNKACGKVPVPQHVAQDQDKVHELVLQSELGVRLLQGRSIKKAFLSPRTALINFLLQE", "length": 903 }, "evidence": [ { "id": "A0A5G2R8T0", "url": "https://omabrowser.org/oma/group/A0A5G2R8T0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HWS5-1", "protein_name": "leucine--tRNA ligase", "gene_name": "Lars2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASACQRLRFYACPLTRQLVCGPPVIQWERRTIPACARSIYSATGTWTKEYTLQTRKDVENWWHRQIKEQASRISEDDKSKPKFYVLSMFPYPSGKLHMGHIRVYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKYMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEYGCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLEFTLKVDGQDTGEKLTAYTATPEAIYGISHVAISPNHRLLHGCSSLKEPLQKVLVPGRDCLTPVMAVNMLTQQEVPIVVMAKADLEGSLDSKIGIPSTSSEDTSIAQALGLPYSEVIETSPDGTERLSGSAEFTGMTRQDAFLALTQKARGMRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPACGPVPVPLQDLPVTLPSITSFTGKGGSPLASALEWVNCPCPRCKRPARRETDTMDTFVDSAWYYLRYTDPQNTHRPFSPALANFWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGLCLKREDIDFTGPAPVCARTKEKLEVTWEKMSKSKHNGVDPEEIVAQYGIDTVRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWSLTTRFIEARTRGSAPQPQLLNNKEETKARNLWEYKNSVITQVTTHFTEDFALNSAVSQLMGLSSALLQASDRVVLHSREFEDALCALLVMAAPMAPHITSELWAGLALVPSKLCDHYAWDAGVMLQAWPTVDSEFLQQPDVVQMAILINNKAYGKISVPQQVAQDQDKVHEFVLQSELGTRLLQGRSIKKAFLSPRTALINFLVQE", "length": 903 }, "evidence": [ { "id": "A0A5G2R8T0", "url": "https://omabrowser.org/oma/group/A0A5G2R8T0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q15031-1", "protein_name": "Leucine--tRNA ligase, mitochondrial", "gene_name": "LARS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFLVQD", "length": 903 }, "evidence": [ { "id": "A0A5G2R8T0", "url": "https://omabrowser.org/oma/group/A0A5G2R8T0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54ET5-1", "protein_name": "Leucine--tRNA ligase, mitochondrial", "gene_name": "mleuS", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNLYRSSLKNLKLPNINNNIKSNLVIRSYTTNINGNIKNDDDNNKFYSLSQFPYPSGALHMGHVRVYTISDCIARLKRMQGYDVIHPMGWDAFGLPAENAAIDKQVSPSEWTNLNISSMRDQLKLLNFQFDWDRELSTCNKEYYRWTQEIFLRLLKSGLAYRKSATVNWDPIDQTVLANEQVDAQGRSWRSNAIVEKKEMKQWFYKITSMADRLTDDLDQLPGWSDEIKNMQKEWIGRSYGHLIEFQSCAQKPLSNITVFTTRAETIYGVSFLAISPHHSEINQIRANLINDEKRLELDQYLKEIQEIKNKMGTQEDVENLKTFNTGLTFYQPITKKYIPLILSNFVHADYGTGAVMGVPSHNRSDYQVAKQQNLKLLPVLGIEREQQQQQQQQQQQQQLEIEEECYDYSNTGKLINSGQDTGIEFKEFIKRLEDQQLIKRQTNYRIHDWLISRQRYWGTPIPIIVCEKCGDVPVPSDQLPVELPIDIQFTGKGNLLNQLDHWKNVKCPCCGSQATRETDTMDTFVDSSWYFLRFLDSKNSQSIFSSELVNRFMPIDVYVGGIEHAILHLLYSRFITKFLKDQQLIDHSEPFKVLLAQGLVKSPTYRDSITNKPIHPSNVEFKTIKSNESGKSQQQTINKLTGNQVSVTIEKMSKSKLNGIDPKEIIDKYGSDTLKTYILFKAPPEKSLDWDTQGIEGCKKWLTRINVSIQSFLNQFDVIEGKEQHQHQQQQHQQPLPSSEFNEQQSKEVKDILFETHLTMNKVTESIDKHSFNTGIAALMELSNTLQKSSPQIKLTKEYYQSLRALTLMLFPFSPIFSQIHWKSLIDDLPQSCKSFYSENYSSFEQQSYGNSNDNDVFNQRWPKPTPSALVRDFNSLVIQFDGKTKGVESIPTSITDFSNFVQSNSKYLNRFKDKTIDQIFIGTTKTGNSINFTFKKK", "length": 940 }, "evidence": [ { "id": "A0A5G2R8T0", "url": "https://omabrowser.org/oma/group/A0A5G2R8T0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VDC0-1", "protein_name": "Probable leucine--tRNA ligase, mitochondrial", "gene_name": "Lars2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTCQRLSFYVSPLKRQLVSRPPVILWERLIPGCSRSIYSATGKWTKEYTLQTRKDVEKWWHQQIKEQASRVSEEDKLKPKFYLLSMFPYPSGKLHMGHVRVYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEYGCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVDGEDTGEKLTAYTATPEAIYGISHVAISPSHGLLHGCSSVKKALQKALVPGRDCLTPVMAVSMLTLQEVPIVIMANPDLEGSLDSKIGIPSTSSEDTRLAQALGLPYSEVIEASPDGTERLSGSAEFTGMTRQDAFVALTRKARGMRVGGHVTSNKLKDWLISRQRYWGTPIPIVHCPACGPVPVPLQDLPVILPSIASLTGRGGSPLATALEWVNCSCPRCKGSAKRETDTMDTFVDSAWYYFRYTDPHNTQSPFGSALADFWMPVDLYIGGKEHAVMHLFYARFLSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQCLKKEDIDFTGPAPVCAKTKEKLEVTWEKMSKSKHNGVDPEEIVAQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWSLTTRFIEARTSGTVPQPQLLNSKEKTKAQNLWEYKNAVIAQVTTHFTEDFALNSVVSQLMGLSSALSQASQRVVLHSPEFEDALCALLVMAAPLAPHVTSELWAGLTLVPSKLCDHYAWDSGVMLQAWPTVDSQFLQKPDMVQMAVLINNKACGKIPVPQHVAQDQDKVHELVLQSELGMKLLQGRSIKKAFLSPRTALINFLVQE", "length": 902 }, "evidence": [ { "id": "A0A5G2R8T0", "url": "https://omabrowser.org/oma/group/A0A5G2R8T0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VZ82-1", "protein_name": "leucine--tRNA ligase", "gene_name": "LeuRS-m", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQALRRTRPWGAVYWNSWRRLLTQSCTRNDNPELTSDVKHRIEAHWREQLSGGQFNPKDSQDKYYVLSMFPYPSGNLHMGHVRVYTIADSVARFQRMCGKNVFQPMGWDSFGLPAENAANQRGVEPASWTEQNIAQMKEQLKRLGCSFDWNHELSTCSPKYYKWTQHLFLMLHRHGLAYQNEALVNWDPVDKTVLADEQVDANGCSWRSGAKVEKKLLRQWFIRTSAYAKQLLDGLEDPTLRDWRDIINLQRHWIGECDGYAFNLLTSASGLLRVWTTHPEHLKDPHAFLVLRSNHHLSKLKGADSLSAANPFAGTTMPVVFSDEVTFPPKSDVYLAAPSFRGEDKDLWDSYGLAFTSNGKDEESLSPANWEMLRKEVLQAATRLNVGGYRVSSKLKDWLISRQRYWGTPIPIVHCQKCGAVPVPEEQLPVSLPPKDSPKEAFLCDCPKCGEKDARRETDTMDTFVDSSWYYLRYLDAQNSERIFDTALTKKFMPVDLYIGGKEHAVLHLYYARFINHFLHSCGLSPTSEPFSRLLVQGMVMGRSFRVKGSGRYVPETEVEIVNAKKNQAVLKETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRLIILADVAPTSHRNWSSATFPGILNWQKRLWLTLQDFQQAREDQTASDVVPTSEEFLAEDAKLFDARNFYVKGATFNYRHAQQLSVAISKMQGLTNSLRRTPKHVLRHGKQFERALAAQIIMLAPMAPHFASELWSKFVAIPGRLNPASQELQWSEDVLAQRWPDIDPAYNLDLSIKVNGFENCVIKVQRTHLDKVTHSDALDIAFNTESVTSYLIDKKIRTTNFVLYPGIEAILNIYVDKAKMKQKPPTTDDAEAQPQA", "length": 869 }, "evidence": [ { "id": "A0A5G2R8T0", "url": "https://omabrowser.org/oma/group/A0A5G2R8T0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9XEA0-1", "protein_name": "Leucine--tRNA ligase, chloroplastic/mitochondrial", "gene_name": "EMB2369", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSHHQILQIRSDPFVLSHCCRHTRLTSSLTLQSPLKQPFSCLPFRWRRSYRGGVRSSTTETHGSKKEALVSETATTSIELKRVYPFHEIEPKWQRYWEDNRIFRTPDDVDTSKPKFYVLDMFPYPSGAGLHVGHPLGYTATDILARLRRMQGYNVLHPMGWDAFGLPAEQYAIETGTHPKTTTLKNIDRFRLQLKSLGFSYDWDRELSTTEPDYYKWTQWIFLQLYKKGLAYQAEVPVNWCPALGTVLANEEVVDGVSERGGHPVIRKPMRQWMLKITAYADRLLEDLDELEWPESIKEMQRNWIGRSEGAELNFSILDGEGRETDKEITVYTTRPDTLFGATYMVVAPEHQLLSYFVTAEQKQQVEEYKDFASRKSDLERTELQKDKTGVFTGCYAKNPANGDAIPIWVADYVLASYGTGAIMAVPAHDTRDNEFALKYNIPIKWVVRNEANSSDDAKQVYPGLGIIENSSTLETGLDINQLSSKEAALKVIEWAERTGNGKKKVNYKLRDWLFARQRYWGEPIPILILDESGETIAISESELPLTLPELNDFTPTGTGEPPLSKAVSWVNTVDPSTGKPAKRETSTMPQWAGSCWYYLRFMDPKNPEALVDKEKEKYWSPVDVYVGGAEHAVLHLLYSRFWHKVLYDIGVVSTKEPFKCVINQGIILGEVQYTAWKDQEGNYVSADTEERLNEHQQVTIPEEKVIKSGDHFVLKEDPSIRLIPRVYKMSKSRGNVVNPDDVVLEYGADSLRLYEMFMGPFRDSKTWNTSGIEGVHRFLARTWRLVIGLPQSDGSFKDGTLVTDDEPTLEQLRTLHKCIAKVTEEIESTRFNTGISGMMEFVNAAYKWNNQPRGIIEPFVLLLSPYAPHMAEELWSRLGHPNSLAYESFPKANPDYLKNTTIVLPVQINGKTRGTIEVEEGCSEDDAFVLASQDDKLRKYLDGQSIKKRIYVPGKILNVILDRTNVKVTTK", "length": 973 }, "evidence": [ { "id": "A0A5G2R8T0", "url": "https://omabrowser.org/oma/group/A0A5G2R8T0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "aminoacyl-tRNA deacylase activity", "id": "GO:0002161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002161", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8T0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0" } ], "pmid": "" }, { "name": "leucine-tRNA ligase activity", "id": "GO:0004823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004823", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8T0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8T0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "leucyl-tRNA aminoacylation", "id": "GO:0006429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006429", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8T0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8T0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8T0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8T0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11688", "name": "", "equation": "tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "11688", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11688" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8T0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 902, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8T0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8T0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0" }, { "id": "PF00133", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00133" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminoacyl-tRNA synthetase class Ia", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 256, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0" }, { "id": "PF13603", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13603" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Leucyl-tRNA synthetase editing", "eco_id": "ECO_0000259", "start_pos": 270, "end_pos": 326, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8T0" }, { "id": "PF08264", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08264" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding", "eco_id": "ECO_0000259", "start_pos": 726, "end_pos": 851, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 502, "end_pos": 504 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R776-1", "uniprot_ac": "A0A5G2R776", "uniprot_id": "A0A5G2R776_PIG", "mass": { "chemical_mass": 41539.0, "monoisotopic_mass": 41539.0 }, "refseq": {}, "gene_names": [ { "name": "TCF7", "type": "recommended", "evidence": [ { "id": "A0A5G2R776", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ] } ], "protein_names": [ { "name": "Transcription factor 7", "type": "recommended", "evidence": [ { "id": "A0A5G2R776", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776/entry#names_and_taxonomy" } ] }, { "name": "T-cell-specific transcription factor 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R776", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TCF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776", "locus": { "chromosome": "2", "start_pos": 136457910, "end_pos": 136422940, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000030680", "url": "https://www.ensembl.org/id/ENSSSCG00000030680" } ] } } ], "crossref": [ { "id": "A0A5G2R776", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R776", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000030680", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000030680", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21996", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21996", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013558", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10373", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10373", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10373:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10373:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27556", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27556", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-201722", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3769402", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3769402", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4641265", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4641265", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8951430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9825892", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9825892", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QUV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R776-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LUM5", "url": "https://www.uniprot.org/uniprotkb/I3LUM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LUM5-1", "url": "https://www.uniprot.org/uniprotkb/I3LUM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQLDSGGGGASGGDDLGAPDELLAFQDEGEEQDDKSRDSAVGPERDLAELKSSLVNESEGAAGDAGVPGAGARARGEAEALGREHTSQRLFSDKLPESLEDGLKAPECASGMYKDTVYSAFNLLMHYPPPSGAGQHPQPQPPLHKASQPSHGVPQLSPLYEHFSSPHPTPAPADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPPLMLGSGVPGHHAAIPHPAIVPPSGKQELQPYDRSLKTQAESKGEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQDSNTGGKRNAFGTYPEKAAAPAPFLPMTVL", "length": 382, "header": "tr|A0A5G2R776-1|A0A5G2R776_PIG Isoform 1 of Transcription factor 7 OS=Sus scrofa OX=9823 GN=TCF7 PE=3 SV=1 CANONICAL=A0A5G2R776-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QUV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776/entry#A0A5G2QUV3-1", "sequence": { "sequence": "MPQLDSGGGGASGGDDLGAPDELLAFQDEGEEQDDKSRDSAVGPERDLAELKSSLVNESEGAAGDAGVPGAGARARGEAEALGREHTSQRLFSDKLPESLEDGLKAPECASGMYKDTVYSAFNLLMHYPPPSGAGQHPQPQPPLHKASQPSHGVPQLSPLYEHFSSPHPTPAPADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPPLMLGSGVPGHHAAIPHPAIVPPSGKQELQPYDRSLKTQAESKGEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQDSNTDPGSPKKCRARFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPKSPAPQDSPSYLLLPHFPTELLASPAEPAPTSPGLSAALSLPAPGPLQASHSDLQSTQVQQPQSQRKAA", "length": 479, "header": "tr|A0A5G2QUV3-1|A0A5G2R776_PIG Computationally mapped isoform of Transcription factor 7 OS=Sus scrofa OX=9823 GN=TCF7 PE=3 SV=1 CANONICAL=A0A5G2R776-1" }, "locus": { "chromosome": "2", "start_pos": 136453887, "end_pos": 136422940, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068918.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068918.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061951.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061951.1" } ] } }, { "isoform_ac": "A0A5G2R776-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776/entry#A0A5G2R776-1", "sequence": { "sequence": "MPQLDSGGGGASGGDDLGAPDELLAFQDEGEEQDDKSRDSAVGPERDLAELKSSLVNESEGAAGDAGVPGAGARARGEAEALGREHTSQRLFSDKLPESLEDGLKAPECASGMYKDTVYSAFNLLMHYPPPSGAGQHPQPQPPLHKASQPSHGVPQLSPLYEHFSSPHPTPAPADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPPLMLGSGVPGHHAAIPHPAIVPPSGKQELQPYDRSLKTQAESKGEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQDSNTGGKRNAFGTYPEKAAAPAPFLPMTVL", "length": 382, "header": "tr|A0A5G2R776-1|A0A5G2R776_PIG Isoform 1 of Transcription factor 7 OS=Sus scrofa OX=9823 GN=TCF7 PE=3 SV=1 CANONICAL=A0A5G2R776-1" }, "locus": { "chromosome": "2", "start_pos": 136453668, "end_pos": 136422940, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071256.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071256.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072190.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072190.1" } ] } }, { "isoform_ac": "I3LUM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776/entry#I3LUM5-1", "sequence": { "sequence": "MYKDTVYSAFNLLMHYPPPSGAGQHPQPQPPLHKASQPSHGVPQLSPLYEHFSSPHPTPAPADISQKQGVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWPSPPLYPLSPSCGYRQHFPAPTAAPGAPYPRFTHPPLMLGSGVPGHHAAIPHPAIVPPSGKQELQPYDRSLKTQAESKGEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQDSNTGGKRNAFGTYPEKAAAPAPFLPMTVL", "length": 302, "header": "tr|I3LUM5-1|A0A5G2R776_PIG Computationally mapped isoform of Transcription factor 7 OS=Sus scrofa OX=9823 GN=TCF7 PE=3 SV=3 CANONICAL=A0A5G2R776-1" }, "locus": { "chromosome": "2", "start_pos": 136453668, "end_pos": 136424009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023234.3", "url": "https://www.ensembl.org/id/ENSSSCT00000023234.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027825.3", "url": "https://www.ensembl.org/id/ENSSSCP00000027825.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 170, "start_aa": "Thr", "end_pos": 170, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr170", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LUM5", "url": "https://www.uniprot.org/uniprotkb/I3LUM5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-201722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201722", "resource": "Reactome", "description": "Formation of the beta-catenin:TCF transactivating complex" }, { "id": "R-SSC-3769402", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3769402", "resource": "Reactome", "description": "Deactivation of the beta-catenin transactivating complex" }, { "id": "R-SSC-4641265", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4641265", "resource": "Reactome", "description": "Repression of WNT target genes" }, { "id": "R-SSC-8951430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951430", "resource": "Reactome", "description": "RUNX3 regulates WNT signaling" }, { "id": "R-SSC-9825892", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9825892", "resource": "Reactome", "description": "Regulation of MITF-M-dependent genes involved in cell cycle and proliferation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" }, { "name": "beta-catenin-TCF complex", "id": "GO:1990907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990907", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" }, { "name": "cellular response to interleukin-4", "id": "GO:0071353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071353", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R776", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R776-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 382, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R776-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R776" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R776", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R776" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 267, "end_pos": 335, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 170 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAH9-1", "uniprot_ac": "A0A5G2RAH9", "uniprot_id": "A0A5G2RAH9_PIG", "mass": { "chemical_mass": 37662.0, "monoisotopic_mass": 37662.0 }, "refseq": {}, "gene_names": [ { "name": "TMBIM1", "type": "recommended", "evidence": [ { "id": "A0A5G2RAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9" } ] } ], "protein_names": [ { "name": "Transmembrane BAX inhibitor motif containing 1", "type": "synonym", "evidence": [ { "id": "A0A5G2RAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAH9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMBIM1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9", "locus": {} } ], "crossref": [ { "id": "A0A5G2RAH9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAH9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016186", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016186", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10428", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10428", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23291", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23291", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23291:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23291:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QWM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7N2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAH9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0NZC0", "url": "https://www.uniprot.org/uniprotkb/A0A8D0NZC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0NZC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0NZC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQPSAPPPYEDRNPLYPGPPPPGGYGQPTVLPGGYPAYPQPGYGHPAGYPQPMPPIHPPMSYGPGHGYGGEERAVSDNFGSGEWSDRKVRHAFIRKVYAIISVQLLITVAIIAIFTFVKPVSNFVRANLAVYYASYAVFLATYLTLICCQGPRRRFPWNIILLTLFTLAMGFMTGTISRMSRSLPGGSPGTPWRRRQGPSDSAAGRGLSDTLFRAGGLHLLHRSLLCPGNCDDGDWDCHCHCAVLQIYLLAAHGLCCPGCHLLHFVPGLRHAAGPGEPEAHHQPRGLHHRRPADLHRHRLHLHLCAAAPGEPELRSASCFALCPGPSLPQRAGPGAGAGPQTSFLPLK", "length": 349, "header": "tr|A0A5G2RAH9-1|A0A5G2RAH9_PIG Isoform 1 of Transmembrane BAX inhibitor motif containing 1 OS=Sus scrofa OX=9823 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A5G2RAH9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9/entry#A0A5G2QWM6-1", "sequence": { "sequence": "MGFMTGTISSVYDTKAVILAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVMMVTGIVTAIVLSFKYIYWLHMVYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIVYIFTFVLQLLGSRN", "length": 137, "header": "tr|A0A5G2QWM6-1|A0A5G2RAH9_PIG Computationally mapped isoform of Transmembrane BAX inhibitor motif containing 1 OS=Sus scrofa OX=9823 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A5G2RAH9-1" }, "locus": { "chromosome": "15", "start_pos": 120352146, "end_pos": 120349938, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074741.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074741.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068550.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068550.1" } ] } }, { "isoform_ac": "A0A5G2R7N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9/entry#A0A5G2R7N2-1", "sequence": { "sequence": "MSQPSAPPPYEDRNPLYPGPPPPGGYGQPTVLPGGYPAYPQPGYGHPAGYPQPMPPIHPPMSYGPGHGYGGEERAVSDNFGSGEWSDRKVRHAFIRKVYAIISVQLLITVAIIAIFTFVKPVSNFVRANLAVYYASYAVFLATYLTLICCQGPRRRFPWNIILLTLFTLAMGFMTGTISRFTGCTWSMLPWVPFASLCSWLTTRSWSWGTGSTPSAPRTTSPAPCRSTPTSSTSSPLCCSSWGAGIKERLLFCPLPRAFPATESWTWGWGWPSDFFPSSQVIAHFPFSPGMGRLSGYGCVGTWWGCRNWGLTPALGGLTGTGPKVCLLPLPTKSLTAGVRVGRDEKS", "length": 347, "header": "tr|A0A5G2R7N2-1|A0A5G2RAH9_PIG Computationally mapped isoform of Transmembrane BAX inhibitor motif containing 1 OS=Sus scrofa OX=9823 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A5G2RAH9-1" }, "locus": { "chromosome": "15", "start_pos": 120356141, "end_pos": 120349634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083022.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083022.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072356.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072356.1" } ] } }, { "isoform_ac": "A0A5G2RAH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9/entry#A0A5G2RAH9-1", "sequence": { "sequence": "MSQPSAPPPYEDRNPLYPGPPPPGGYGQPTVLPGGYPAYPQPGYGHPAGYPQPMPPIHPPMSYGPGHGYGGEERAVSDNFGSGEWSDRKVRHAFIRKVYAIISVQLLITVAIIAIFTFVKPVSNFVRANLAVYYASYAVFLATYLTLICCQGPRRRFPWNIILLTLFTLAMGFMTGTISRMSRSLPGGSPGTPWRRRQGPSDSAAGRGLSDTLFRAGGLHLLHRSLLCPGNCDDGDWDCHCHCAVLQIYLLAAHGLCCPGCHLLHFVPGLRHAAGPGEPEAHHQPRGLHHRRPADLHRHRLHLHLCAAAPGEPELRSASCFALCPGPSLPQRAGPGAGAGPQTSFLPLK", "length": 349, "header": "tr|A0A5G2RAH9-1|A0A5G2RAH9_PIG Isoform 1 of Transmembrane BAX inhibitor motif containing 1 OS=Sus scrofa OX=9823 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A5G2RAH9-1" }, "locus": { "chromosome": "15", "start_pos": 120356141, "end_pos": 120349834, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085673.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085673.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067613.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067613.1" } ] } }, { "isoform_ac": "A0A8D0NZC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9/entry#A0A8D0NZC0-1", "sequence": { "sequence": "MAASWFYAAWRCPPALGSPATGSPLSPRVAMSQPSAPPPYEDRNPLYPGPPPPGGYGQPTVLPGGYPAYPQPGYGHPAGYPQPMPPIHPPMSYGPGHGYGGEERAVSDNFGSGEWSDRKVRHAFIRKVYAIISVQLLITVAIIAIFTFVKPVSNFVRANLAVYYASYAVFLATYLTLICCQGPRRRFPWNIILLTLFTLAMGFMTGTISSVYDTKAVILAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVMMVTGIVTAIVLSFKYIYWLHMVYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIVYIFTFVLQLLGSRN", "length": 337, "header": "tr|A0A8D0NZC0-1|A0A5G2RAH9_PIG Computationally mapped isoform of Transmembrane BAX inhibitor motif containing 1 OS=Sus scrofa OX=9823 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A5G2RAH9-1" }, "locus": { "chromosome": "15", "start_pos": 120363209, "end_pos": 120349938, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017626.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017626.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017148.4", "url": "https://www.ensembl.org/id/ENSSSCP00000017148.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWM6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAH9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAH9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAH9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAH9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAH9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "id": "GO:1902042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902042", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAH9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAH9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 349, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAH9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAH9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R890-1", "uniprot_ac": "A0A5G2R890", "uniprot_id": "A0A5G2R890_PIG", "mass": { "chemical_mass": 121386.0, "monoisotopic_mass": 121386.0 }, "refseq": {}, "gene_names": [ { "name": "AP2A2", "type": "recommended", "evidence": [ { "id": "A0A5G2R890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890" } ] } ], "protein_names": [ { "name": "Adaptor related protein complex 2 subunit alpha 2", "type": "synonym", "evidence": [ { "id": "A0A5G2R890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ02", "url": "https://www.uniprot.org/uniprotkb/F1RZ02#function" }, { "database": "UniProtKB", "id": "PIRNR037091", "url": "https://www.uniprot.org/uniprotkb/PIRNR037091#function" }, { "database": "UniProtKB", "id": "A0A5G2QEC4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEC4#function" }, { "database": "UniProtKB", "id": "A0A5G2R7F9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F9#function" }, { "database": "UniProtKB", "id": "A0A5G2R8R7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R890", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AP2A2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890", "locus": { "chromosome": "2", "start_pos": 628087, "end_pos": 580182, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012836", "url": "https://www.ensembl.org/id/ENSSSCG00000012836" } ] } } ], "crossref": [ { "id": "A0A5G2R890", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R890", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012836", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012836", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012295", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012295", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02296", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02296", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02883", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02883", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2132295", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-416993", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416993", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-437239", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-437239", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5099900", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5099900", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5140745", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5140745", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8866427", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8866427", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8964038", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964038", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QEC4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QEC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWT4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7F9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7F9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R890", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R890-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8R7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ02", "url": "https://www.uniprot.org/uniprotkb/F1RZ02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ02-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPQGQEVWLHSKFRHQEPGLVGEALTGPFPVGKGPALVRQMCVLAKASRKRWGCRGGLRGVPGRGQFLAGEREVRAVPGRRPQRRVWRRPGEPSVRASVSAGSAVRCLGGCPGSPAPREENRETQALPEEGLSWQTSLRLSKSGGGSHKCERKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAVKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAALFEAISLVIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVTNALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAVLAEKYAVDYTWYVDTILGLIRVAGDFVSEEVWYRVIQIVVNRDDAQGYAAKTVFEALQAPACHENLVKVGGYVLGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKGTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSILAKLKRKKGPSTVTDLEEAKRDRGADVNGGPEPAPASASAASTPSPSADLLGLGAAPPVPAGPPPSSGGLLVDVFSDSPSAVAPLAPGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLSFTPTLVCSDGLQANILVLRTQPVGPTVDGGAQVQQAVNIECLSDFAEAPVLSVQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSSPQQEVQSIFRAKHPMDTEVTKAKIIGFGSALLEDVDPNPANFVGAGIIHTKTSQIGCLLRLEPNLQAQVKPLEETAKYTPVVVLCCCFGLGFFGLFRATAAASGGPQARGRIGATAAGLHHSHNHARSEPRL", "length": 1109, "header": "tr|A0A5G2R890-1|A0A5G2R890_PIG Isoform 1 of Adaptor related protein complex 2 subunit alpha 2 OS=Sus scrofa OX=9823 GN=AP2A2 PE=1 SV=2 CANONICAL=A0A5G2R890-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QEC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890/entry#A0A5G2QEC4-1", "sequence": { "sequence": "VHKLNLQKRKRYPRCPRNFGYLFISVLVNSNSELIRLINNAVKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAALFEAISLVIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVTNALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAVLAEKYAVDYTWYVDTILGLIRVAGDFVSEEVWYRVIQIVVNRDDAQGYAAKTVFEALQAPACHENLVKVGGYVLGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKGTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSILAKLKRKKGPSTVTDLEEAKRDRGADVNGGPEPAPASASAASTPSPSADLLGLGAAPPVPAGPPPSSGGLLVDVFSDSPSAVAPLAPGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLSFTPTLVCSDGLQANILVLRTQPVGPTVDGGAQVQQAVNIECLSDFAEAPVLSVQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSSPQQEVQSIFRAKHPMDTEVTKAKIIGFGSALLEDVDPNPANFVGAGIIHTKTSQIGCLLRLEPNLQAQVKPLEETAKYTPVVVLCCCFGLGFFGLFRATAAASGGPQARGRIGATAAGLHHSHNHARSEPRL", "length": 903, "header": "tr|A0A5G2QEC4-1|A0A5G2QEC4_PIG Computationally mapped isoform of AP-2 complex subunit alpha OS=Sus scrofa OX=9823 GN=AP2A2 PE=1 SV=2 CANONICAL=A0A5G2R890-1" }, "locus": { "chromosome": "2", "start_pos": 627355, "end_pos": 604213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076283.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076283.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060396.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060396.2" } ] } }, { "isoform_ac": "A0A5G2QWT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890/entry#A0A5G2QWT4-1", "sequence": { "sequence": "MEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAVKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAALFEAISLVIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVTNALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAVLAEKYAVDYTWYVDTILGLIRVAGDFVSEEVWYRVIQIVVNRDDAQGYAAKTVFEALQAPACHENLVKVGGYVLGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKGTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSILAKLKRKKGPSTVTDLEEAKRDRGADVNGGPEPAPASASAASTPSPSADLLGLGAAPPVPAGPPPSSGGLLVDVFSDSPSAVAPLAPGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLSFTPTLVCSDGLQANILPVGPTVDGGAQVQQAVNIECLSDFAEAPVLSVQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSSPQQEVQSIFRAKHPMDTEVTKAKIIGFGSALLEDVDPNPANFVGAGIIHTKTSQIGCLLRLEPNLQAQMYRLTLRTSRETVSQRLCELLSEQF", "length": 857, "header": "tr|A0A5G2QWT4-1|A0A5G2R890_PIG Computationally mapped isoform of Adaptor related protein complex 2 subunit alpha 2 OS=Sus scrofa OX=9823 GN=AP2A2 PE=1 SV=1 CANONICAL=A0A5G2R890-1" }, "locus": { "chromosome": "2", "start_pos": 627796, "end_pos": 603459, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077450.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077450.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062644.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062644.1" } ] } }, { "isoform_ac": "A0A5G2R7F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890/entry#A0A5G2R7F9-1", "sequence": { "sequence": "MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAVKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAALFEAISLVIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVTNALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAVLAEKYAVDYTWYVDTILGLIRVAGDFVSEEVWYRVIQIVVNRDDAQGYAAKTVFEALQAPACHENLVKVGGYVLGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKGTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSILAKLKRKKGPSTVTDLEEAKRDRGADVNGGPEPAPASASSTPSPSADLLGLGAAPPVPAGPPPSSGGLLVDVFSDSPSAVAPLAVSRVWGRGGGDDSALAPGPGHGRAPPGPPPGPSRALPGRPPAASCLLGFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLSFTPTLVCSDGLQANILVPWPRPSGVQRRVLRFCVGVGRRACSLRVPSRAPGVYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSSPQQEVQSIFRAKHPMDTEVTKAKIIGFGSALLEDVDPNPANFVGAGIIHTKTSQIGCLLRLEPNLQAQVKPLEETAKYTPVVVLCCCFGLGFFGLFRATAAASGGPQARGRIGATAAGLHHSHNHARSEPRL", "length": 1011, "header": "tr|A0A5G2R7F9-1|A0A5G2R7F9_PIG Computationally mapped isoform of AP-2 complex subunit alpha OS=Sus scrofa OX=9823 GN=AP2A2 PE=1 SV=2 CANONICAL=A0A5G2R890-1" }, "locus": { "chromosome": "2", "start_pos": 627355, "end_pos": 580364, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071891.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071891.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073182.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073182.2" } ] } }, { "isoform_ac": "A0A5G2R890-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890/entry#A0A5G2R890-1", "sequence": { "sequence": "MAAPQGQEVWLHSKFRHQEPGLVGEALTGPFPVGKGPALVRQMCVLAKASRKRWGCRGGLRGVPGRGQFLAGEREVRAVPGRRPQRRVWRRPGEPSVRASVSAGSAVRCLGGCPGSPAPREENRETQALPEEGLSWQTSLRLSKSGGGSHKCERKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAVKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAALFEAISLVIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVTNALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAVLAEKYAVDYTWYVDTILGLIRVAGDFVSEEVWYRVIQIVVNRDDAQGYAAKTVFEALQAPACHENLVKVGGYVLGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKGTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSILAKLKRKKGPSTVTDLEEAKRDRGADVNGGPEPAPASASAASTPSPSADLLGLGAAPPVPAGPPPSSGGLLVDVFSDSPSAVAPLAPGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLSFTPTLVCSDGLQANILVLRTQPVGPTVDGGAQVQQAVNIECLSDFAEAPVLSVQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSSPQQEVQSIFRAKHPMDTEVTKAKIIGFGSALLEDVDPNPANFVGAGIIHTKTSQIGCLLRLEPNLQAQVKPLEETAKYTPVVVLCCCFGLGFFGLFRATAAASGGPQARGRIGATAAGLHHSHNHARSEPRL", "length": 1109, "header": "tr|A0A5G2R890-1|A0A5G2R890_PIG Isoform 1 of Adaptor related protein complex 2 subunit alpha 2 OS=Sus scrofa OX=9823 GN=AP2A2 PE=1 SV=2 CANONICAL=A0A5G2R890-1" }, "locus": { "chromosome": "2", "start_pos": 627355, "end_pos": 593045, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070503.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070503.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070337.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070337.2" } ] } }, { "isoform_ac": "A0A5G2R8R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890/entry#A0A5G2R8R7-1", "sequence": { "sequence": "MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAVKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAALFEAISLVIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVTNALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAVLAEKYAVDYTWYVDTILGLIRVAGDFVSEEVWYRVIQIVVNRDDAQGYAAKTVFEALQAPACHENLVKVGGYVLGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKGTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSILAKLKRKKGPSTVTDLEEAKRDRGADVNGGPEPAPASASAASTPSPSADLLGLGAAPPVPAGPPPSSGGLLVDVFSDSPSAVAPLAPGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLSFTPTLVCSDGLQANILVLRTQPVGPTVDGGAQVQQAVNIECLSDFAEAPVLSVQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSSPQQEVQSIFRAKHPMDTEVTKAKIIGFGSALLEDVDPNPANFVGAGIIHTKTSQIGCLLRLEPNLQAQVKPLEETAKYTPVVVLCCCFGLGFFGLFRATAAASGGPQARGRIGATAAGLHHSHNHARSEPRL", "length": 943, "header": "tr|A0A5G2R8R7-1|A0A5G2R8R7_PIG Computationally mapped isoform of AP-2 complex subunit alpha OS=Sus scrofa OX=9823 GN=AP2A2 PE=1 SV=2 CANONICAL=A0A5G2R890-1" }, "locus": { "chromosome": "2", "start_pos": 627355, "end_pos": 580364, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088202.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088202.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067003.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067003.2" } ] } }, { "isoform_ac": "F1RZ02-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890/entry#F1RZ02-1", "sequence": { "sequence": "MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAVKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAALFEAISLVIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVTNALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAVLAEKYAVDYTWYVDTILGLIRVAGDFVSEEVWYRVIQIVVNRDDAQGYAAKTVFEALQAPACHENLVKVGGYVLGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKGTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSILAKLKRKKGPSTVTDLEEAKRDRGADVNGGPEPAPASASSTPSPSADLLGLGAAPPVPAGPPPSSGGLLVDVFSDSPSAVAPLAVSRVWGRGGGDDSALAPGPGHGRAPPGPPPGPSRALPGRPPAASCLLGFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLSFTPTLVCSDGLQANILPVGPTVDGGAQVQQAVNIECLSDFAEAPVLSVQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSSPQQEVQSIFRAKHPMDTEVTKAKIIGFGSALLEDVDPNPANFVGAGIIHTKTSQIGCLLRLEPNLQAQMYRLTLRTSRETVSQRLCELLSEQF", "length": 971, "header": "tr|F1RZ02-1|A0A5G2R890_PIG Computationally mapped isoform of Adaptor related protein complex 2 subunit alpha 2 OS=Sus scrofa OX=9823 GN=AP2A2 PE=1 SV=4 CANONICAL=A0A5G2R890-1" }, "locus": { "chromosome": "2", "start_pos": 627796, "end_pos": 580364, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014031.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014031.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013646.4", "url": "https://www.ensembl.org/id/ENSSSCP00000013646.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 786, "start_aa": "Thr", "end_pos": 786, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr786", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 908, "start_aa": "Thr", "end_pos": 908, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr908", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ02", "url": "https://www.uniprot.org/uniprotkb/F1RZ02" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2132295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "resource": "Reactome", "description": "MHC class II antigen presentation" }, { "id": "R-SSC-416993", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416993", "resource": "Reactome", "description": "Trafficking of GluR2-containing AMPA receptors" }, { "id": "R-SSC-437239", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-437239", "resource": "Reactome", "description": "Recycling pathway of L1" }, { "id": "R-SSC-5099900", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5099900", "resource": "Reactome", "description": "WNT5A-dependent internalization of FZD4" }, { "id": "R-SSC-5140745", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5140745", "resource": "Reactome", "description": "WNT5A-dependent internalization of FZD2, FZD5 and ROR2" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-SSC-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" }, { "id": "R-SSC-8866427", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8866427", "resource": "Reactome", "description": "VLDLR internalisation and degradation" }, { "id": "R-SSC-8964038", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964038", "resource": "Reactome", "description": "LDL clearance" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R890", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R890", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890" } ], "pmid": "" }, { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R890", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "AP-2 adaptor complex", "id": "GO:0030122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030122", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R890", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R890", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R890", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R890", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890" } ], "pmid": "" }, { "name": "disordered domain specific binding", "id": "GO:0097718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097718", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R890", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 874, "end_pos": 876, "annotation": "n_glycosylation_sequon" }, { "start_pos": 945, "end_pos": 947, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R890-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1109, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R890-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R890" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R890" }, { "id": "SM00809", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00809" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain", "eco_id": "ECO_0000259", "start_pos": 837, "end_pos": 951, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 786, 908 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 874, "end_pos": 876 }, { "start_pos": 945, "end_pos": 947 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RFX2-1", "uniprot_ac": "A0A5G2RFX2", "uniprot_id": "A0A5G2RFX2_PIG", "mass": { "chemical_mass": 93067.0, "monoisotopic_mass": 93067.0 }, "refseq": {}, "gene_names": [ { "name": "SLCO5A1", "type": "recommended", "evidence": [ { "id": "A0A5G2RFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2" } ] } ], "protein_names": [ { "name": "Solute carrier organic anion transporter family member", "type": "recommended", "evidence": [ { "id": "A0A5G2RFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLCO5A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2", "locus": { "chromosome": "4", "start_pos": 65587240, "end_pos": 65439237, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006196", "url": "https://www.ensembl.org/id/ENSSSCG00000006196" } ] } } ], "crossref": [ { "id": "A0A5G2RFX2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006196", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006196", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17404", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17404", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11388:SF142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11388:SF142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QX19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX19-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEGIGLQPQAGEQLEAPARVGAVQEQCEPETFRSKSLPVLNSASCRSDRRPAREGSEPASGCTDSSDHRELKQGPGPQAPSPSARSTSAEMVGLVEHHHRVEVGKTMSVSSALAMLQGRRCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGSLVVVVFVSYFGGRGRRPLWLAVGGLLIAVGAALFALPHFISPPYQIRELNASASNDGLCQNGNFSATVEPPTCLKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENASLYLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLNQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKMKKKKYSANVAGDDDVVKEKPNSCEQADKKVSSIGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVVIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTRPHRNLTGSCNVNCGCKIHEYKPVCGSDGITYFNPCLAGCVHSGNMSTGIRNYTECTCVQSRQVITPTVGQRSQLRVVIVKTYLNANGYAVSGKCKRTCNTLIPFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEEELQRQRWREFPLSTVSEMVGHTDSADKYARTRSCPAFNTQGEFHEETGLQKGIQYTAQTYPGPFPEAISSSPDPGLEESPAAMPPS", "length": 853, "header": "tr|A0A5G2RFX2-1|A0A5G2RFX2_PIG Isoform 1 of Solute carrier organic anion transporter family member OS=Sus scrofa OX=9823 GN=SLCO5A1 PE=3 SV=1 CANONICAL=A0A5G2RFX2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QX19-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2/entry#A0A5G2QX19-1", "sequence": { "sequence": "MDEGIGLQPQAGEQLEAPARVGAVQEQCEPETFRSKSLPVLNSASCRSDRRPAREGSEPASGCTDSSDHRELKQGPGPQAPSPSARSTSAEMVGLVEHHHRVEVGKTMSVSSALAMLQGRRCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGSLVVVVFVSYFGGRGRRPLWLAVGGLLIAVGAALFALPHFISPPYQIRELNASASNDGLCQNGNFSATVEPPTCLKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENASLYLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLNQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKMKKKKYSANVAGDDDVVKEKPNSCEQADKKVSSIGFGKDVRGVVIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTRPHRNLTGSCNVNCGCKIHEYKPVCGSDGITYFNPCLAGCVHSGNMSTGIRNYTECTCVQSRQVITPTVGQRSQLRVVIVKTYLNANGYAVSGKCKRTCNTLIPFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEEELQRQRWREFPLSTVSEMVGHTDSADKYARTRSCPAFNTQGEFHEETGLQKGIQYTAQTYPGPFPEAISSSPDPGLEESPAAMPPS", "length": 798, "header": "tr|A0A5G2QX19-1|A0A5G2RFX2_PIG Computationally mapped isoform of Solute carrier organic anion transporter family member OS=Sus scrofa OX=9823 GN=SLCO5A1 PE=3 SV=1 CANONICAL=A0A5G2RFX2-1" }, "locus": { "chromosome": "4", "start_pos": 65583210, "end_pos": 65441618, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090749.3", "url": "https://www.ensembl.org/id/ENSSSCT00000090749.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066484.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066484.1" } ] } }, { "isoform_ac": "A0A5G2RFX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2/entry#A0A5G2RFX2-1", "sequence": { "sequence": "MDEGIGLQPQAGEQLEAPARVGAVQEQCEPETFRSKSLPVLNSASCRSDRRPAREGSEPASGCTDSSDHRELKQGPGPQAPSPSARSTSAEMVGLVEHHHRVEVGKTMSVSSALAMLQGRRCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGSLVVVVFVSYFGGRGRRPLWLAVGGLLIAVGAALFALPHFISPPYQIRELNASASNDGLCQNGNFSATVEPPTCLKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENASLYLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLNQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKMKKKKYSANVAGDDDVVKEKPNSCEQADKKVSSIGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVVIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTRPHRNLTGSCNVNCGCKIHEYKPVCGSDGITYFNPCLAGCVHSGNMSTGIRNYTECTCVQSRQVITPTVGQRSQLRVVIVKTYLNANGYAVSGKCKRTCNTLIPFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEEELQRQRWREFPLSTVSEMVGHTDSADKYARTRSCPAFNTQGEFHEETGLQKGIQYTAQTYPGPFPEAISSSPDPGLEESPAAMPPS", "length": 853, "header": "tr|A0A5G2RFX2-1|A0A5G2RFX2_PIG Isoform 1 of Solute carrier organic anion transporter family member OS=Sus scrofa OX=9823 GN=SLCO5A1 PE=3 SV=1 CANONICAL=A0A5G2RFX2-1" }, "locus": { "chromosome": "4", "start_pos": 65583210, "end_pos": 65441618, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081924.3", "url": "https://www.ensembl.org/id/ENSSSCT00000081924.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073792.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073792.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 616, "start_aa": "Thr", "end_pos": 616, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr616", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX19" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2" } ], "pmid": "" }, { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2" } ], "pmid": "" }, { "name": "sodium-independent organic anion transport", "id": "GO:0043252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043252", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RFX2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 853, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RFX2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFX2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 552, "end_pos": 605, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFX2" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 763, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 616 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 231, "end_pos": 233 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 472, "end_pos": 474 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 732, "end_pos": 734 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAK9-1", "uniprot_ac": "A0A5G2RAK9", "uniprot_id": "A0A5G2RAK9_PIG", "mass": { "chemical_mass": 62436.0, "monoisotopic_mass": 62436.0 }, "refseq": {}, "gene_names": [ { "name": "GRK4", "type": "recommended", "evidence": [ { "id": "A0A5G2RAK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor kinase", "type": "recommended", "evidence": [ { "id": "A0A5G2RAK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.-", "type": "synonym", "evidence": [ { "id": "A0A5G2RAK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GRK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9", "locus": { "chromosome": "8", "start_pos": 1792374, "end_pos": 1738333, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008694", "url": "https://www.ensembl.org/id/ENSSSCG00000008694" } ] } } ], "crossref": [ { "id": "A0A5G2RAK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008694", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008694", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05605", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05605", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519668", "url": "https://www.ncbi.nlm.nih.gov/gene/100519668", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519668", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519668", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PFRPDPN", "url": "https://omabrowser.org/oma/group/PFRPDPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S8P7", "url": "https://www.orthodb.org/?gene=F1S8P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24355", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24355", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24355:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24355:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2514859", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2514859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "12008", "url": "https://www.rhea-db.org/rhea/12008", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QYX0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAK9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S8P7", "url": "https://www.uniprot.org/uniprotkb/F1S8P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S8P7-1", "url": "https://www.uniprot.org/uniprotkb/F1S8P7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELENILANSLLLKARQEKEYSSLCDKQPIGRLLFRQFCATRPALGRCVEFLDAVAEYEVAADEDQGACGLSVLDTFFGDELAAPFAEVPAQAVQECRLRLQEAPSKDAFEECTRAIHHYLSGEPFGEYQESSYFSRFLQWKWLERQPVTKKTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKRRKGEAMALNEKTLLEKVHSRFVVSLCYTYETRAALCLVLTIMNGGDLKFHIYNLGEPGFEERRAVFYAAELCCGLGDLHRERIVYRDLKPENILLDDRGHIRISDLGLAVQIPEDKTVHGRVGTLGYMAPEVLNNENYTFSPDWWGLGCLIYEMIQGHSPFKKFKEKVRRDEVERRVRKEAEKYSEKFSQEAKAICSLLLTKDPKQRLGCKGEGVAEVKRHPVFKDINFRRLEATMLEPPFCPDPQAVYCKNVFDIEQFSSVKGVYLDSTDAAFYREFVTGCVSIPWQNEMIESECFKDINESEIEEAEAEDPEEDAHLPVPRRRRSLFHRLLTRGGCISTGPSDNEEDPWPG", "length": 545, "header": "tr|A0A5G2RAK9-1|A0A5G2RAK9_PIG Isoform 1 of G protein-coupled receptor kinase OS=Sus scrofa OX=9823 GN=GRK4 PE=3 SV=1 CANONICAL=A0A5G2RAK9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9/entry#A0A5G2QYX0-1", "sequence": { "sequence": "MELENILANSLLLKARQEKEYSSLCDKQPIGRLLFRQFCATRPALGRCVEFLDAVAEYEVAADEDQGACGLSVLDTFFGDELAAPFAEVPAQAVQECRLRLQEAPSKDAFEECTRAIHHYLSGEPFGEYQESSYFSRFLQWKWLERQPVTKKTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKRRKGEAMALNEKTLLEKVHSRFVVSLCYTYETRAALCLVLTIMNGGDLKFHIYNLGEPGFEERRAVFYAAELCCGLGDLHRERIVYRDLKPENILLDDRGHIRISDLGLAVQIPEDKTVHGRVGTLGYMAPEVLNNENYTFSPDWWGLGCLIYEMIQGHSPFKKFKEKVRRDEVERRVRKEAEKYSEKFSQEAKAICSLLLTKDPKQRLGCKGEGVAEVKRHPVFKDINFRRLEATMLEPPFCPDPQAVYCKNVFDIEQFSSVKGVYLDSTDAAFYREFVTGCVSIPWQNEGCISTGPSDNEEDPWPG", "length": 499, "header": "tr|A0A5G2QYX0-1|A0A5G2RAK9_PIG Computationally mapped isoform of G protein-coupled receptor kinase OS=Sus scrofa OX=9823 GN=GRK4 PE=3 SV=2 CANONICAL=A0A5G2RAK9-1" }, "locus": { "chromosome": "8", "start_pos": 1792236, "end_pos": 1738532, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082591.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082591.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063430.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063430.2" } ] } }, { "isoform_ac": "A0A5G2RAK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9/entry#A0A5G2RAK9-1", "sequence": { "sequence": "MELENILANSLLLKARQEKEYSSLCDKQPIGRLLFRQFCATRPALGRCVEFLDAVAEYEVAADEDQGACGLSVLDTFFGDELAAPFAEVPAQAVQECRLRLQEAPSKDAFEECTRAIHHYLSGEPFGEYQESSYFSRFLQWKWLERQPVTKKTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKRRKGEAMALNEKTLLEKVHSRFVVSLCYTYETRAALCLVLTIMNGGDLKFHIYNLGEPGFEERRAVFYAAELCCGLGDLHRERIVYRDLKPENILLDDRGHIRISDLGLAVQIPEDKTVHGRVGTLGYMAPEVLNNENYTFSPDWWGLGCLIYEMIQGHSPFKKFKEKVRRDEVERRVRKEAEKYSEKFSQEAKAICSLLLTKDPKQRLGCKGEGVAEVKRHPVFKDINFRRLEATMLEPPFCPDPQAVYCKNVFDIEQFSSVKGVYLDSTDAAFYREFVTGCVSIPWQNEMIESECFKDINESEIEEAEAEDPEEDAHLPVPRRRRSLFHRLLTRGGCISTGPSDNEEDPWPG", "length": 545, "header": "tr|A0A5G2RAK9-1|A0A5G2RAK9_PIG Isoform 1 of G protein-coupled receptor kinase OS=Sus scrofa OX=9823 GN=GRK4 PE=3 SV=1 CANONICAL=A0A5G2RAK9-1" }, "locus": { "chromosome": "8", "start_pos": 1792236, "end_pos": 1738532, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068403.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068403.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074057.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074057.1" } ] } }, { "isoform_ac": "F1S8P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9/entry#F1S8P7-1", "sequence": { "sequence": "MELENILANSLLLKARQGGRSKKSGRSKKWREMLRLPPVSQCSELRQSLEKEYSSLCDKQPIGRLLFRQFCATRPALGRCVEFLDAVAEYEVAADEDQGACGLSVLDTFFGDEDLAAPFAEVPAQAVQECRLRLQEAPSKDAFEECTRAIHHYLSGEPFGEYQESSYFSRFLQWKWLERQPVTKKTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKRRKGEAMALNEKTLLEKVHSRFVVSLCYTYETRAALCLVLTIMNGGDLKFHIYNLGEPGFEERRAVFYAAELCCGLGDLHRERIVYRDLKPENILLDDRGHIRISDLGLAVQIPEDKTVHGRVGTLGYMAPEVLNNENYTFSPDWWGLGCLIYEMIQGHSPFKKFKEKVRRDEVERRVRKEAEKYSEKFSQEAKAICSLLLTKDPKQRLGCKGEGVAEVKRHPVFKDINFRRLEATMLEPPFCPDPQAVYCKNVFDIEQFSSVKGVYLDSTDAAFYREFVTGCVSIPWQNEMIESECFKDINESEIEEAEAEDPEEDAHLPVPRRRRSLFHRLLTRGGCISTGPSDNEEQLSRL", "length": 578, "header": "tr|F1S8P7-1|F1S8P7_PIG Computationally mapped isoform of G protein-coupled receptor kinase OS=Sus scrofa OX=9823 GN=GRK4 PE=3 SV=4 CANONICAL=A0A5G2RAK9-1" }, "locus": { "chromosome": "8", "start_pos": 1792220, "end_pos": 1738532, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009512.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009512.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009268.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009268.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYX0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYX0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519668", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519668", "resource": "KEGG Pathway" }, { "id": "R-SSC-2514859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2514859", "resource": "Reactome", "description": "Inactivation, recovery and regulation of the phototransduction cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7EU15-1", "protein_name": "G protein-coupled receptor kinase", "gene_name": "Grk4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MELENLVANTLLLKARQAGQSKKSGRSRKWKEILKLPPVSLCSELRNSIEKDFSSLCDKQPIGRNLFRQFCDTKPCLKRCIDFLDAVAEYEVTVEEEQREFGLSILHRFFKEKSEVPLPEIPIAVVKECKWNLKENSSSKNVFEECARFVYTYLSEKPFEEYQDSKYFRRFLQWKWLERRPVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKRRKSEGMALNEKRILEKLHSRFVVSLAYTYETKDTLCLVLTIMNGGDLKYHIYNLGNPGFEEPRAVFYAAELCCGLEDLQKERIVYRDLKPENILLDDHGHIRISDLGLALEVPEGEMVRGRVGTVGYMSPEIINNERYAFSPDWWGLGCLIYEMIAGHTPFKKYKEKVTREELERRVKNDTEEYSEKFSEDAKSICSMLLIKDPSYRLGCQSNGAAAVKQHPVFKDINFSRLEANMLDPPFCPDPQAIYCKDILDIGRFSVVKGVNLDSSDETFYAQFATGCVSIPWQNEMIESGCFHDLNEAADEGDATSHKKEKMCPSILRPKRNFLRRIFRRGVKKSFVIKVNCCGWGYCLG", "length": 580 }, "evidence": [ { "id": "A0A5G2RAK9", "url": "https://omabrowser.org/oma/group/A0A5G2RAK9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O70291-1", "protein_name": "G protein-coupled receptor kinase 4", "gene_name": "Grk4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELENFVANNLLLKARLGFNKQTGRSKKWRELLKFPPVSMCTELRWSIEKDFSSLCDKQPIGRLLFRQFCDTKPDLKRCIEFLDAVAEYEVTIEEEQREFGLAIFSRFFKEKSEVPLPEIPPDIVKECKWNLKQNSPSQNVFEECAGIVCKYLSETPFEEYQESTYFNRFLQWKWLERRPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEKLHSRFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGDPGFEEPRAVFYAAELCCGLEDLQRKRIVYRDLKPENILLDDHGHIRISDLGLAMEVPEGEMVRGRVGTVGYMAPEIINHEKYTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREELERRVKNETEEYSERFSEDAKSICSMLLIKDPSKRLGCQRDGVSAVKQHPIFKDINFSRLEANMLDPPFIPDPQAIYCRNILDIGQFSVVKGVNLDTNDEIFYAEFATGSVTIPWQNEMIESGCFKDLNENEDDLSSLEKYKMCSSILRPKRNFFRRLFRRTGCLNIALSEEREPTEH", "length": 574 }, "evidence": [ { "id": "A0A5G2RAK9", "url": "https://omabrowser.org/oma/group/A0A5G2RAK9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P32298-1", "protein_name": "G protein-coupled receptor kinase 4", "gene_name": "GRK4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPEIPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQPVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLDIEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEEALPLDLDKNIHTPVSRPNRGFFYRLFRRGGCLTMVPSEKEVEPKQC", "length": 578 }, "evidence": [ { "id": "A0A5G2RAK9", "url": "https://omabrowser.org/oma/group/A0A5G2RAK9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70507-1", "protein_name": "G protein-coupled receptor kinase 4", "gene_name": "Grk4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELENFMANTLLLKARQGFTKKTGRSKKWRELLKLPPVSMCSDLRHSIEKDFSSLCDQQPIGRLLFRQFCNTKPDLKRCIEFLDAAAEYEVTIEEEQREFGLSIYSRFFKENSEVSLPQIPPDLVKECKCNLKQSSPSQNVFQDCAGVIYKYLSEKPFEEYQESTYYNRFLQWKWLERRPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEKLHSRFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGNPGFEEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDHGHIRISDLGLALEIPEGEMVRGRVGTVGYMAPEIISHEKYTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREEMERRVKTETEEYSERFSENAKSICSMLLTKDPSKRLGCQSDGASAVKQHPIFKDINFSRLEANMLDPPFCPDPEAIYCKDILDIGQFSVVKGVNLDTNDEIFYTQFATGCVTIPWQNEMIESGCFKDLNEYEDKGLSPLEKHKICSCILRPKRNFFHRLFRRAACLNIAHSEEREPTEH", "length": 575 }, "evidence": [ { "id": "A0A5G2RAK9", "url": "https://omabrowser.org/oma/group/A0A5G2RAK9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" } ], "pmid": "" }, { "name": "G protein-coupled receptor kinase activity", "id": "GO:0004703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004703", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" } ], "pmid": "" }, { "name": "receptor internalization", "id": "GO:0031623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031623", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12008", "name": "", "equation": "[G protein-coupled receptor] + ATP = [G protein-coupled receptor]-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12008", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12008" } ] }, { "id": "R-SSC-2581474", "name": "GRK1,4,7 phosphorylate MII to p-MII", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, photoreceptor disc membrane", "input_participant_list": [ "R-SSC-5205901" ], "output_participant_list": [ "R-SSC-5205903" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2581474", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2581474" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-5205901", "participant_name": "at-retinyl-RHO [photoreceptor disc membrane]", "crossref": [ { "id": "O18766", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000011590", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000012353", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000012686", "database": "ENSEMBL", "url": "" }, { "id": "NP_999386.1", "database": "RefSeq", "url": "" }, { "id": "92283", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-5205903", "participant_name": "phospho-p-S334,338,343-at-retinyl-RHO [photoreceptor disc membrane]", "crossref": [ { "id": "ENSSSCT00000012686", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000011590", "database": "ENSEMBL", "url": "" }, { "id": "92283", "database": "VGNC", "url": "" }, { "id": "O18766", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000012353", "database": "ENSEMBL", "url": "" }, { "id": "NP_999386.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAK9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 545, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAK9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAK9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" }, { "id": "PS51285", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51285" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AGC-kinase C-terminal", "eco_id": "ECO_0000259", "start_pos": 417, "end_pos": 482, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RAK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 416, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RAK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK9" }, { "id": "PS50132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RGS", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 139, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 329, "end_pos": 331 }, { "start_pos": 493, "end_pos": 495 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAM9-1", "uniprot_ac": "A0A5G2RAM9", "uniprot_id": "A0A5G2RAM9_PIG", "mass": { "chemical_mass": 56907.0, "monoisotopic_mass": 56907.0 }, "refseq": {}, "gene_names": [ { "name": "CEP57", "type": "recommended", "evidence": [ { "id": "A0A5G2RAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ] } ], "protein_names": [ { "name": "Centrosomal protein of 57 kDa", "type": "recommended", "evidence": [ { "id": "A0A5G2RAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9/entry#names_and_taxonomy" } ] }, { "name": "Translokin", "type": "synonym", "evidence": [ { "id": "A0A5G2RAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CEP57", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9", "locus": {} } ], "crossref": [ { "id": "A0A5G2RAM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014969", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014969", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100739524", "url": "https://www.ncbi.nlm.nih.gov/gene/100739524", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100739524", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739524", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMKQMIA", "url": "https://omabrowser.org/oma/group/YMKQMIA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QKE8", "url": "https://www.orthodb.org/?gene=A0A5G2QKE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19336:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19336:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06657", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06657", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14073", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14073", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QKE8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0G7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STI6", "url": "https://www.uniprot.org/uniprotkb/F1STI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STI6-1", "url": "https://www.uniprot.org/uniprotkb/F1STI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAASVSETSASQFSNILAEPSSSGSMVRHSSSPYVVYPPDKPFLNSDLRRSPNKPTFAYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSKETIEYKKVLDEQIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQTHVQNQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLREEEQERKRMQAKAAQLQTGLETNRLIFEDKATSCVPNAKRIKKKKSRPSEKKGSRNCCAAQPHYRLCLGDMPFVAGKSTSPSHAVVANVQHVLHLMKQHSKVLCNDRVINNVPLAKQVPSRGGKSKKSATPPSSSSINEELSEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQKIEKQKRELRTTKKTLDEEGNSSSRSSATTGTINKKDFAKPRPGEKSRKNLQLLKDMQTIQNSLQSNNLCWDY", "length": 499, "header": "tr|A0A5G2RAM9-1|A0A5G2RAM9_PIG Isoform 1 of Centrosomal protein of 57 kDa OS=Sus scrofa OX=9823 GN=CEP57 PE=3 SV=1 CANONICAL=A0A5G2RAM9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QKE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9/entry#A0A5G2QKE8-1", "sequence": { "sequence": "MAAASVSETSASQFSVAVHCWDPQGWLPNAPRAAKAGLLGHVGVTARLESAPRPEHLSRTIKSSGSMVRHSSSPYVVYPPDKPFLNSDLRRSPNKPTFAYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSKETIEYKKVLDEQIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQTHVQNQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLREEEQERKRMQAKAAQLQTGLETNRLIFEDKATSCVPNAKRIKKKKSRPSEKKGSRNCCAAQPHYRLCLGDMPFVAGKSTSPSHAVVANVQHVLHLMKQHSKVLCNDRVINNVPLAKQVPSRGGKSKKSATPPSSSSINEELSEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQKIEKQKRELRTTKKTLDEEGNSSSRSSATTGTINKKDFAKPRPGEKSRKNLQLLKDMQTIQNSLQSNNLCWDY", "length": 539, "header": "tr|A0A5G2QKE8-1|A0A5G2QKE8_PIG Computationally mapped isoform of Centrosomal protein of 57 kDa OS=Sus scrofa OX=9823 GN=CEP57 PE=3 SV=2 CANONICAL=A0A5G2RAM9-1" }, "locus": { "chromosome": "9", "start_pos": 27857315, "end_pos": 27813143, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066710.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066710.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062537.2", "url": "https://www.ensembl.org/id/ENSSSCP00000062537.2" } ] } }, { "isoform_ac": "A0A5G2R0G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9/entry#A0A5G2R0G7-1", "sequence": { "sequence": "MAAASVSETSASQFSNILAEPSSSGSMVRHSSSPYVVYPPDKPFLNSDLRRSPNKPTFAYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSKETIEYKKVLDEQIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQTHVQNQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLREEEQERKRMQAKAAQLQTGLETNRLIFEDKATSCVPNAKRIKKKKSRPSEKSTSPSHAVVANVQHVLHLMKQHSKVLCNDRVINNVPLAKQVPSRGGKSKKSATPPSSSSINEELSEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQKIEKQKRELRTTKKTLDEEGNSSSRSSATTGTINKKDFAKPRPGEKSRKNLQLLKDMQTIQNSLQSNNLCWDY", "length": 473, "header": "tr|A0A5G2R0G7-1|A0A5G2RAM9_PIG Computationally mapped isoform of Centrosomal protein of 57 kDa OS=Sus scrofa OX=9823 GN=CEP57 PE=3 SV=1 CANONICAL=A0A5G2RAM9-1" }, "locus": { "chromosome": "9", "start_pos": 27857315, "end_pos": 27813143, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071563.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071563.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070645.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070645.1" } ] } }, { "isoform_ac": "A0A5G2RAM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9/entry#A0A5G2RAM9-1", "sequence": { "sequence": "MAAASVSETSASQFSNILAEPSSSGSMVRHSSSPYVVYPPDKPFLNSDLRRSPNKPTFAYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSKETIEYKKVLDEQIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQTHVQNQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLREEEQERKRMQAKAAQLQTGLETNRLIFEDKATSCVPNAKRIKKKKSRPSEKKGSRNCCAAQPHYRLCLGDMPFVAGKSTSPSHAVVANVQHVLHLMKQHSKVLCNDRVINNVPLAKQVPSRGGKSKKSATPPSSSSINEELSEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQKIEKQKRELRTTKKTLDEEGNSSSRSSATTGTINKKDFAKPRPGEKSRKNLQLLKDMQTIQNSLQSNNLCWDY", "length": 499, "header": "tr|A0A5G2RAM9-1|A0A5G2RAM9_PIG Isoform 1 of Centrosomal protein of 57 kDa OS=Sus scrofa OX=9823 GN=CEP57 PE=3 SV=1 CANONICAL=A0A5G2RAM9-1" }, "locus": { "chromosome": "9", "start_pos": 27857315, "end_pos": 27813143, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087854.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087854.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074384.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074384.1" } ] } }, { "isoform_ac": "F1STI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9/entry#F1STI6-1", "sequence": { "sequence": "MVRHSSSPYVVYPPDKPFLNSDLRRSPNKPTFAYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSKETIEYKKVLDEQIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQTHVQNQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLREEEQERKRMQAKAAQLQTGLETNRLIFEDKATSCVPNAKRIKKKKSRPSEKKGSRNCCAAQPHYRLCLGDMPFVAGKSTSPSHAVVANVQHVLHLMKQHSKVLCNDRVINNVPLAKQVPSRGGKSKKSATPPSSSSINEELSEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQKIEKQKRELRTTKKTLDEEGNSSSRSSATTGTINKKDFAKPRPGEKSRKNLQLLKDMQTIQNSLQSNNLCWDY", "length": 473, "header": "tr|F1STI6-1|F1STI6_PIG Computationally mapped isoform of Centrosomal protein of 57 kDa OS=Sus scrofa OX=9823 GN=CEP57 PE=3 SV=3 CANONICAL=A0A5G2RAM9-1" }, "locus": { "chromosome": "9", "start_pos": 27857315, "end_pos": 27822391, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016330.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016330.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015892.3", "url": "https://www.ensembl.org/id/ENSSSCP00000015892.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0G7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100739524", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739524", "resource": "KEGG Pathway" }, { "id": "R-SSC-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-SSC-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-SSC-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-SSC-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-SSC-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-SSC-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-SSC-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XT96-1", "protein_name": "Centrosomal protein 57", "gene_name": "CEP57", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAARGQQRTGDVCRAPRSASATDGLSAASYLDYPTHKPFINSDLLRSPQKPVVPYPESNSRAIFSALRNLQEKIRRLELERLQAEENVKHLSRETADYKKVLSEQMQHRERDRTEVSKRNQELASQLAAAESRYSLLEKQLDYMRKMIQHAEREKTQLLEKQDSLERERLDQSHVQSKLEKLDMLEKEYTRLTTMQSIAEKKMKELEQKLQEEEHARKLVQEKAAELQTGLETNRLLIQAASPLLSPKARKPRKKTKQPEKKCSLTSHLTTQPHYRLCLGDVPFVAGKSTSPSHSVGANVQHVLHLMKHHTKALCNSRVVNDTPLAKSISAGRPGSRSRKPPLPKDYSSSQEELSEVLLTLQDEFGQMSFDHQQLSKLVQEAPTIAVREDLERELEALVGKMEAKADQISKVRRHWLQLERLKREYKSKKASAKHKKDNKFPVSEVKVTTTVTTKGKDAGPIKVKPGEKSRKNLQLLRDMQTIQTSLQKDDISWDY", "length": 497 }, "evidence": [ { "id": "A0A5G2RAM9", "url": "https://omabrowser.org/oma/group/A0A5G2RAM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MM87-1", "protein_name": "Centrosomal protein of 57 kDa", "gene_name": "CEP57", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAASVSETSASQFSNILAEPSKSNGSMVRHSSSPYVVYPPDKPFLNSDLRRSPNKPTFAYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSKETIEYKKVLDEQIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQTHVQNQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLRQEEQERKRMQAKAAQLQTGLEVNRLIYEDKATSCVPNTKRIKKKKSKPPEKKGSRNYFAVQPHYRLCLGDMPFVAGKSTSPSHAVVANVQHVLHLMKQHSKVLCNDRVVSSIPLAKQVSSRTGKSKKSATPPSSSSVNEELSEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQKLEKQKKELKATRKTLDEEGNSSSRSTTTGTTNKKDFAKPRPGEKSRKNLQLLKDMQSIQNSLQSNSLCWDY", "length": 499 }, "evidence": [ { "id": "A0A5G2RAM9", "url": "https://omabrowser.org/oma/group/A0A5G2RAM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86XR8-1", "protein_name": "Centrosomal protein of 57 kDa", "gene_name": "CEP57", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLAYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLETNRLIFEDKATPCVPNARRIKKKKSKPPEKKSSRNYFGAQPHYRLCLGDMPFVAGKSTSPSHAVVANVQLVLHLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSNGINEELSEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRKYQAQLEKQKLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKLRPGEKRRKNLQLLKDMQSIQNSLQSSSLCWDY", "length": 500 }, "evidence": [ { "id": "A0A5G2RAM9", "url": "https://omabrowser.org/oma/group/A0A5G2RAM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CEE0-1", "protein_name": "Centrosomal protein of 57 kDa", "gene_name": "Cep57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAASVSAASDSQFSSVLAEPSRSNGNMVRHSSSPYVLYPPDKPFLNSDLRRSPNKPTFAYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKNEESKHNQELASQLVAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTAMQALAEKKMQELESKLREEEQERKRMQARAAELQSGLEANRLIFEDKTTSCVSTSTRKIKKKKSKPPEKKGSRTYFGAQPHYRLCLGDMPFVAGTSTSPSHAVVANVQHVLHLMKHHSKALCNDRVVNSVPLAKQACSRVSKSKKSVVPPSSSVNEELSDVLQTLQDEFGQMSFDHQQLTKLIQESPTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQNIDKQKKELKANKKTLDEEGNSSGRSSGVPRTASKKDLAKQRPGEKSRKNLQLLKDMQTIQNSLQSSNLCWDY", "length": 500 }, "evidence": [ { "id": "A0A5G2RAM9", "url": "https://omabrowser.org/oma/group/A0A5G2RAM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" }, { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" }, { "name": "fibroblast growth factor binding", "id": "GO:0017134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017134", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor signaling pathway", "id": "GO:0008543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008543", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAM9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 499, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAM9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAM9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" }, { "id": "PF14073", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14073" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cep57 centrosome localisation", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 243, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM9" }, { "id": "PF06657", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06657" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cep57 centrosome microtubule-binding", "eco_id": "ECO_0000259", "start_pos": 347, "end_pos": 418, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 447, "end_pos": 449 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RCC1-1", "uniprot_ac": "A0A5G2RCC1", "uniprot_id": "A0A5G2RCC1_PIG", "mass": { "chemical_mass": 29630.0, "monoisotopic_mass": 29630.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1", "locus": {} } ], "crossref": [ { "id": "A0A5G2RCC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044550", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044550", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSSSCG00000046449", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000046449", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R3F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3F8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGNQTSVLEFLLLGLSQDSEQQPILFGLFLSMFVVTVFGNLLIILAISSDPHLHTPMYFFLSNLSLADICFTSTTIPKMLVNIQTQSKAISYVGCITQVYFFMVVGGMDTFLLTVMAYDRFVAICHPLLSYSLSQSLLMLRLSFCSSWAIPHFHCELSQALMLLVTGFLGIVPFSGILCSYTRIVSSILRISSAHGKYKAFSTCVSHLSVVSLFYGTGLGVYLSSEPSSWRGMVASVMYTVVTPMLNPFIYSLRNRDIKRPCPLV", "length": 267, "header": "tr|A0A5G2RCC1-1|A0A5G2RCC1_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RCC1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R3F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1/entry#A0A5G2R3F8-1", "sequence": { "sequence": "MEPGNQTSVLEFLLLGLSQDSEQQPILFGLFLSMFVVTVFGNLLIILAISSDPHLHTPMYFFLSNLSLADICFTSTTIPKMLVNIQTQSKAISYVGCITQVYFFMVVGGMDTFLLTVMAYDRFVAICHPLLSYSLSQSLLMLRLSFCSSWAIPHFHCELSQALMLLVTGFLGIVPFSGILCSYTRIVSSILRISSAHGKYKAFSTCVSHLSVVSLFYGTGLGVYLSSEPSSWRGMVASVMYTVVTPMLNPFIYIQTHHC", "length": 259, "header": "tr|A0A5G2R3F8-1|A0A5G2RCC1_PIG Computationally mapped isoform of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RCC1-1" }, "locus": { "chromosome": "2", "start_pos": 67723511, "end_pos": 67722289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082752.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082752.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068732.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068732.2" } ] } }, { "isoform_ac": "A0A5G2RCC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1/entry#A0A5G2RCC1-1", "sequence": { "sequence": "MEPGNQTSVLEFLLLGLSQDSEQQPILFGLFLSMFVVTVFGNLLIILAISSDPHLHTPMYFFLSNLSLADICFTSTTIPKMLVNIQTQSKAISYVGCITQVYFFMVVGGMDTFLLTVMAYDRFVAICHPLLSYSLSQSLLMLRLSFCSSWAIPHFHCELSQALMLLVTGFLGIVPFSGILCSYTRIVSSILRISSAHGKYKAFSTCVSHLSVVSLFYGTGLGVYLSSEPSSWRGMVASVMYTVVTPMLNPFIYSLRNRDIKRPCPLV", "length": 267, "header": "tr|A0A5G2RCC1-1|A0A5G2RCC1_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RCC1-1" }, "locus": { "chromosome": "2", "start_pos": 67723511, "end_pos": 67722176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072489.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072489.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074031.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074031.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3F8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RCC1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 267, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RCC1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCC1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 152, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8J0-1", "uniprot_ac": "A0A5G2R8J0", "uniprot_id": "A0A5G2R8J0_PIG", "mass": { "chemical_mass": 140563.0, "monoisotopic_mass": 140563.0 }, "refseq": {}, "gene_names": [ { "name": "TCOF1", "type": "recommended", "evidence": [ { "id": "A0A5G2R8J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0" } ] } ], "protein_names": [ { "name": "Treacle ribosome biosis factor 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R8J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TCOF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0", "locus": { "chromosome": "2", "start_pos": 151401027, "end_pos": 151368289, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014450", "url": "https://www.ensembl.org/id/ENSSSCG00000014450" } ] } } ], "crossref": [ { "id": "ENSSSCG00000014450", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014450", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100516425", "url": "https://www.ncbi.nlm.nih.gov/gene/100516425", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516425", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516425", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VYDTPRN", "url": "https://omabrowser.org/oma/group/VYDTPRN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RL66", "url": "https://www.orthodb.org/?gene=F1RL66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20787", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20787", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20787:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20787:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R479", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R479", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R479-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R479-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6Q2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8J0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RL66", "url": "https://www.uniprot.org/uniprotkb/F1RL66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RL66-1", "url": "https://www.uniprot.org/uniprotkb/F1RL66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQRTPKVLHLNTALRAGNEAQVLRQDRRRPCGDTQGSFPAEVDAAVRSERREKSFLTQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISSSESSEEEEEEEEAAEARNAKATPRPASTNSSVPGPVLPSSIKDEGAAKTKKASQTGNPTARAASGKPVAQLLGQKSPRKAAGPSANAVLASETEEEGSVSALRTAAKPGMTAASQAHSSSEDTSSSSDETDVEGKPLVAPAQVKASAATAQEPPRKRAPPTPGKAGAGTPQGRGGTLTPASRAKKPEEVSESSEEESESDDQAPASTPSQTKASEKTQVRAASGPARGAPGKGATPAPPGRAGPAAARDKVVKPEEGSESSSEEASSSSDSEEEAPAAKTPPQAKPPGKVPGVRATSAAPAKESPRKGAPPAPASRAAQAGQREEDSESSSEESDAGGQAAAAAPQTSSPALVKPMGQNSHGRAPRALAGKGAVPALPGQAGQQDSGSSSEDSDSGDSEEEAATTAKPSEKVLPARTASGPSTGPPQKARPAATQVKAERSESSEESSTDSEEEAPAAAAAAQAKPAVKTPQTKASPRKGGPVTPASAKAAPVRVGTPAPWKAGATTASPATAKAAQRPEADSSSSETSESEEEEEEAPPAAAAGRMKNSVTAPQTKATPAVPRVASAKVAASAPGKGAPAGAQATLGSPAKVRPPARTPQGRPGAGKGPGAVPAVGKAATTAAPQPGPVGGAEDDSESSDGDSDSEEAAPAQAKPTRKTPQVRAASAPSKASPRKGAAPAPAGKTGPPATQAGKPTEDSESSSEESSGSDGEAPPAQGGGCSPASGRPPAATASAGKAEQKKTKEEKAEGPSASSDDELPASQVIKTPLIFVDPNRSPAGPAATLAQAQATSAGRKVQASESTAGSSSESEDEDVVPATQCSAPALRTSSATAPPVPPRTAPRASSGKEPGQAAEGRKPEAPATQVTKRSPADLPLTQAALKVLAQKASEGRPAAARTPSSCATDGLGTLPTTRPQSAPAQTRGANELRKPGVPAAPPSKRPKAKASGTSEDSEDGSSSSSSGSEDDAAGPRVAPGAPGPGAAPARKETLVEETTAESSDDEVVAPSQSLLSGYVTPGLTPGTSQASKTTPKPAPSPSVSSPPATKDALGGKRGAEAPRAAGTTSPKSGRGEAGATPQRPREGPESPQASRLALQHDIARRLLGEPWPLSEAHVQASVAKVLTELLEQERRKAADAAREGRRKGRKRKLSEDQTAAKAPKSKKKKQLAAGEGGERAVSPDKAPRTCQGKPKRDRAGGASKEKQEKEAPGSQGAKEKLEGEPGMVKGEGGDQGAPRSKKEKKKPDKSKCSRRPAGSCPHAGGQPLASTGPRLACPGSRGRIGRARARFGTTGPPLPRG", "length": 1399, "header": "tr|A0A5G2R8J0-1|A0A5G2R8J0_PIG Isoform 1 of Treacle ribosome biosis factor 1 OS=Sus scrofa OX=9823 GN=TCOF1 PE=1 SV=1 CANONICAL=A0A5G2R8J0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R479-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0/entry#A0A5G2R479-1", "sequence": { "sequence": "MAEARKRRELLPLIYQHLLQAGYVRAAREVKEQSGQKSFLTQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISSSESSEEEEEEEEAAEARNAKATPRPASTNSSVPGPVLPSSIKDEGAAKTKKASQTGNPTARAASGKPVAQLLGQKSPRKAAGPSANAVLASETEEEGSVSALRTAAKPGMTAASQAHSSSEDTSSSSDETDVEGKPLVAPAQVKASAATAQEPPRKRAPPTPGKAGAGTPQGRGGTLTPASRAKKPEEVSESSEEESESDDQAPASTPSQTKASEKTQVRAASGPARGAPGKGATPAPPGRAGPAAARDKVVKPEEGSESSSEEASSSSDSEEEAPAAKTPPQVKPMGQNSHGRAPRALAGKGAVPALPGQAGQQDSGSSSEDSDSGDSEEEAATTAKPSEKVLPARTASGPSTGPPQKARPAATQVKAERSESSEESSTDSEEEAPAAAAAAQAKPAVKTPQTKASPRKGGPVTPASAKAAPVRVGTPAPWKAGATTASPATAKAAQRPEADSSSSETSESEEEEEEAPPAAAAGRMKNSVTAPQTKATPAVPRVASAKVAASAPGKGAPAGAQATLGSPAKVRPPARTPQGRPGAGKGPGAVPAVGKAATTAAPQPGPVGGAEDDSESSDGDSDSEEAAPAQAKPTRKTPQVRAASAPSKASPRKGAAPAPAGKTGPPATQAGKPTEDSESSSEESSGSDGEAPPAQGGGCSPASGRPPAATASAGKAEQKKTKEEKAEGPSASSDDELPASQVIKTPLIFVDPNRSPAGPAATLAQAQATSAGRKVQASESTAGSSSESEDEDVVPATQCSAPALRTSSATAPPVPPRTAPRASSGKEPGQAAEGRKPEAPATQVTKRSPADLPLTQAALKVLAQKASEGRPAAARTPSSCATDGLGTLPTTRPQSAPAQTRGANELRKPGVPAAPPSKRPKAKASGTSEDSEDGSSSSSSGSEDDAAGPRVAPGAPGPGAAPARKETLVEETTAESSDDEVVAPSQSLLSGYVTPGLTPGTSQASKTTPKPAPSPSVSSPPATKDALGGKRGAEAPRAAGTTSPKSGRGEAGATPQRPREGPESPQASRLALQHDIARRLLGEPWPLSEAHVQASVAKVLTELLEQERRKAADAAREGRRKGRKRKLSEDQTAAKAPKSKKKKQLAAGEGGERAVSPDKAPRTCQGKPKRDRAGGASKEKQEKEAPGSQGAKEKLEGEPGMVKGEGGDQGAPRSKKEKKKPDKKKKDKEKREKKKKAKKASTKAPDSPCQKKKKKKV", "length": 1295, "header": "tr|A0A5G2R479-1|A0A5G2R8J0_PIG Computationally mapped isoform of Treacle ribosome biosis factor 1 OS=Sus scrofa OX=9823 GN=TCOF1 PE=1 SV=1 CANONICAL=A0A5G2R8J0-1" }, "locus": { "chromosome": "2", "start_pos": 151399487, "end_pos": 151368377, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082901.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082901.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071891.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071891.1" } ] } }, { "isoform_ac": "A0A5G2R6Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0/entry#A0A5G2R6Q2-1", "sequence": { "sequence": "MAEARKRRELLPLIYQHLLQAGYVRAAREVKEQSGQKSFLTQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISSSESSEEEEEEEEAAEARNAKATPRPASTNSSVPGPVLPSSIKDEGAAKTKKASQTGNPTARAASGKPVAQLLGQKSPRKAAGPSANAVLASETEEEGSVSALRTAAKPGMTAASQAHSSSEDTSSSSDETDVEGKPLVAPAQVKASAATAQEPPRKRAPPTPGKAGAGTPQGRGGTLTPASRAKKPEEVSESSEEESESDDQAPASTPSQTKASEKTQVRAASGPARGAPGKGATPAPPGRAGPAAARDKVVKPEEGSESSSEEASSSSDSEEEAPAAKTPPQVKPMGQNSHGRAPRALAGKGAVPALPGQAGQQDSGSSSEDSDSGDSEEEAATTAKPSEKVLPARTASGPSTGPPQKARPAATQVKAERSESSEESSTDSEEEAPAAAAAAQAKPAVKTPQTKASPRKGGPVTPASAKAAPVRVGTPAPWKAGATTASPATAKAAQRPEADSSSSETSESEEEEEEAPPAAAAGRMKNSVTAPQTKATPAVPRVASAKVAASAPGKGAPAGAQATLGSPAKVRPPARTPQGRPGAGKGPGAVPAVGKAATTAAPQPGPVGGAEDDSESSDGDSDSEEAAPAQAKPTRKTPQVRAASAPSKASPRKGAAPAPAGKTGPPATQAGKPTEDSESSSEESSGSDGEAPPAQGGGCSPASGRPPAATASAGKAEQKKTKEEKAEGPSASSDDELPASQVIKTPLIFVDPNRSPAGPAATLAQAQATSAGRKVQASESTAGSSSESEDEDVVPATQCSAPALRTSSATAPPVPPRTAPRASSGKEPGQAAEGRKPEAPATQVPGGRGALAALPTASSWLGLPPALSRAVLRTDGLGTLPTTRPQSAPAQTRGANELRKPGVPAAPPSKRPKAKASGTSEDSEDGSSSSSSGSEDDAAGPRVAPGAPGPGAAPARKETLVEETTAESSDDEVVAPSQSLLSGYVTPGLTPGTSQASKTTPKPAPSPSVSSPPATKDALGGKRGAEAPRAAGTTSPKSGRGEAGATPQRPREGPESPQASRLALQHDIARRLLGEPWPLSEAHVQASVAKVLTELLEQERRKAADAAREGRRKGRKRKLSEDQTAAKAPKSKKKKQLAAGEGGERAVSPDKAPRTCQGKPKRDRAGGASKEKQEKEAPGSQGAKEKLEGEPGMVKGEGGDQGAPRSKKEKKKPDKKKKDKEKREKKKKAKKASTKAPDSPCQKKKKKKV", "length": 1287, "header": "tr|A0A5G2R6Q2-1|A0A5G2R8J0_PIG Computationally mapped isoform of Treacle ribosome biosis factor 1 OS=Sus scrofa OX=9823 GN=TCOF1 PE=1 SV=2 CANONICAL=A0A5G2R8J0-1" }, "locus": { "chromosome": "2", "start_pos": 151399487, "end_pos": 151368377, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083743.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083743.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072759.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072759.2" } ] } }, { "isoform_ac": "A0A5G2R8J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0/entry#A0A5G2R8J0-1", "sequence": { "sequence": "MNQRTPKVLHLNTALRAGNEAQVLRQDRRRPCGDTQGSFPAEVDAAVRSERREKSFLTQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISSSESSEEEEEEEEAAEARNAKATPRPASTNSSVPGPVLPSSIKDEGAAKTKKASQTGNPTARAASGKPVAQLLGQKSPRKAAGPSANAVLASETEEEGSVSALRTAAKPGMTAASQAHSSSEDTSSSSDETDVEGKPLVAPAQVKASAATAQEPPRKRAPPTPGKAGAGTPQGRGGTLTPASRAKKPEEVSESSEEESESDDQAPASTPSQTKASEKTQVRAASGPARGAPGKGATPAPPGRAGPAAARDKVVKPEEGSESSSEEASSSSDSEEEAPAAKTPPQAKPPGKVPGVRATSAAPAKESPRKGAPPAPASRAAQAGQREEDSESSSEESDAGGQAAAAAPQTSSPALVKPMGQNSHGRAPRALAGKGAVPALPGQAGQQDSGSSSEDSDSGDSEEEAATTAKPSEKVLPARTASGPSTGPPQKARPAATQVKAERSESSEESSTDSEEEAPAAAAAAQAKPAVKTPQTKASPRKGGPVTPASAKAAPVRVGTPAPWKAGATTASPATAKAAQRPEADSSSSETSESEEEEEEAPPAAAAGRMKNSVTAPQTKATPAVPRVASAKVAASAPGKGAPAGAQATLGSPAKVRPPARTPQGRPGAGKGPGAVPAVGKAATTAAPQPGPVGGAEDDSESSDGDSDSEEAAPAQAKPTRKTPQVRAASAPSKASPRKGAAPAPAGKTGPPATQAGKPTEDSESSSEESSGSDGEAPPAQGGGCSPASGRPPAATASAGKAEQKKTKEEKAEGPSASSDDELPASQVIKTPLIFVDPNRSPAGPAATLAQAQATSAGRKVQASESTAGSSSESEDEDVVPATQCSAPALRTSSATAPPVPPRTAPRASSGKEPGQAAEGRKPEAPATQVTKRSPADLPLTQAALKVLAQKASEGRPAAARTPSSCATDGLGTLPTTRPQSAPAQTRGANELRKPGVPAAPPSKRPKAKASGTSEDSEDGSSSSSSGSEDDAAGPRVAPGAPGPGAAPARKETLVEETTAESSDDEVVAPSQSLLSGYVTPGLTPGTSQASKTTPKPAPSPSVSSPPATKDALGGKRGAEAPRAAGTTSPKSGRGEAGATPQRPREGPESPQASRLALQHDIARRLLGEPWPLSEAHVQASVAKVLTELLEQERRKAADAAREGRRKGRKRKLSEDQTAAKAPKSKKKKQLAAGEGGERAVSPDKAPRTCQGKPKRDRAGGASKEKQEKEAPGSQGAKEKLEGEPGMVKGEGGDQGAPRSKKEKKKPDKSKCSRRPAGSCPHAGGQPLASTGPRLACPGSRGRIGRARARFGTTGPPLPRG", "length": 1399, "header": "tr|A0A5G2R8J0-1|A0A5G2R8J0_PIG Isoform 1 of Treacle ribosome biosis factor 1 OS=Sus scrofa OX=9823 GN=TCOF1 PE=1 SV=1 CANONICAL=A0A5G2R8J0-1" }, "locus": { "chromosome": "2", "start_pos": 151398568, "end_pos": 151369086, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066641.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066641.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066928.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066928.1" } ] } }, { "isoform_ac": "F1RL66-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0/entry#F1RL66-1", "sequence": { "sequence": "MAEARKRRELLPLIYQHLLQAGYVRAAREVKEQSGQKSFLTQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISSSESSEEEEEEEEAAEARNAKATPRPASTNSSVPGPVLPSSIKDEGAAKTKKASQTGNPTARAASGKPVAQLLGQKSPRKAAGPSANAVLASETEEEGSVSALRTAAKPGMTAASQAHSSSEDTSSSSDETDVEGKPLVAPAQVKASAATAQEPPRKRAPPTPGKAGAGTPQGRGGTLTPASRAKKPEEVSESSEEESESDDQAPASTPSQTKASEKTQVRAASGPARGAPGKGATPAPPGRAGPAAARDKVVKPEEGSESSSEEASSSSDSEEEAPAAKTPPQAKPPGKVPGVRATSAAPAKESPRKGAPPAPASRAAQAGQREEDSESSSEESDAGGQAAAAAPQTSSPALVKPMGQNSHGRAPRALAGKGAVPALPGQAGQQDSGSSSEDSDSGDSEEEAATTAKPSEKVLPARTASGPSTGPPQKARPAATQVKAERSESSEESSTDSEEEAPAAAAAAQAKPAVKTPQTKASPRKGGPVTPASAKAAPVRVGTPAPWKAGATTASPATAKAAQRPEADSSSSETSESEEEEEEAPPAAAAGRMKNSVTAPQTKATPAVPRVASAKVAASAPGKGAPAGAQATLGSPAKVRPPARTPQGRPGAGKGPGAVPAVGKAATTAAPQPGPVGGAEDDSESSDGDSDSEEAAPAQAKPTRKTPQVRAASAPSKASPRKGAAPAPAGKTGPPATQAGKPTEDSESSSEESSGSDGEAPPAQGGGCSPASGRPPAATASAGKAEQKKTKEEKAEGPSASSDDELPASQVIKTPLIFVDPNRSPAGPAATLAQAQATSAGRKVQASESTAGSSSESEDEDVVPATQCSAPALRTSSATAPPVPPRTAPRASSGKEPGQAAEGRKPEAPATQVTKRSPADLPLTQAALKVLAQKASEGRPAAARTPSSCATDGLGTLPTTRPQSAPAQTRGANELRKPGVPAAPPSKRPKAKASGTSEDSEDGSSSSSSGSEDDAAGPRVAPGAPGPGAAPARKETLVEETTAESSDDEVVAPSQSLLSGYVTPGLTPGTSQASKTTPKPAPSPSVSSPPATKDALGGKRGAEAPRAAGTTSPKSGRGEAGATPQRPREGPESPQASRLALQHDIARRLLGEPWPLSEAHVQASVAKVLTELLEQERRKAADAAREGRRKGRKRKLSEDQTAAKAPKSKKKKQLAAGEGGERAVSPDKAPRTCQGKPKRDRAGGASKEKQEKEAPGSQGAKEKLEGEPGMVKGEGGDQGAPRSKKEKKKPDKKKKDKEKREKKKKAKKASTKAPDSPCQKKKKKKKKTAEQTV", "length": 1371, "header": "tr|F1RL66-1|A0A5G2R8J0_PIG Computationally mapped isoform of Treacle ribosome biosis factor 1 OS=Sus scrofa OX=9823 GN=TCOF1 PE=1 SV=3 CANONICAL=A0A5G2R8J0-1" }, "locus": { "chromosome": "2", "start_pos": 151400073, "end_pos": 151368377, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015798.4", "url": "https://www.ensembl.org/id/ENSSSCT00000015798.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015382.3", "url": "https://www.ensembl.org/id/ENSSSCP00000015382.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1118, "start_aa": "Thr", "end_pos": 1118, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1118", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 262, "start_aa": "Thr", "end_pos": 262, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr262", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 308, "start_aa": "Thr", "end_pos": 308, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr308", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 585, "start_aa": "Thr", "end_pos": 585, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr585", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R479", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R479" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516425", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516425", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A206-1", "protein_name": "Treacle ribosome biogenesis factor 1", "gene_name": "Tcof1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEARKRRELLPLIYHHLLQAGYVRAAREVKEQSGQKNFLTHPVTLLDIYTHWQQTSELGLKQKAENDETLQAKKSRVSDPISSSESSEEEEEEAETGTAKATPRPTPVNSTAAALPSNMKQKAKTKTANKTVNSVLPPASGKTAVQLLSGKSPKKSAEPLASIVLASETEEEGSAQVLGPTAKPGMVSAGQASSSSEDTSSSSDETDVEVKPSTKPQAKAPVTPAKDPPARTASGPTKLGDVTPASARAAATKAAESESSEEDSESEDEAPAGLPSQVTTPGKGLHVRAASVSAKGMSRKGPISATPEKTGPITPQAKTGRPQKDMETSSEDDSDSEDEMPVTVTTPQARPSGKSPQVRGTSAPAKESSQKGAPAVTPGKTRPVAAQAQAGKPETRSSEESESDSGETPAAGTLTTSPAKVKPLGKSPQVRPASTANLGSSRKGANPPCLGKVGSAVLKVQTGKEEEDSESSSEESDSDGAVNAAKAKPPGRKATPALPRKTGPVATQVKTDKGKDHAESSEESTDSEEEAAPAASAAQAKPAPIKQMKASPRKGTAASTTGASASSPRKAGTKTSSASLSSLALPKGTQKPDVDSSSEWESEGAAPGTTGVQGKSGGKGLQGRAASGQGVAPLHAQKTGPSGAQVKATAQEDSESSEEESSSEEEDETPAQVMALGRLPPAKANPPPTKTPLASASGKAAAVVPPPKGKAPASTVQNSTISARGQRAVPATGKAGAPATQAQKGPMAGTGEDSESSSEEESDSEEETPAQVKPVGKTSQVRAASAPVKESPNKGAYSGTSRKTGPPATQAQTGKTEDSESSSEESDSDREIPPAITPAQDGISQSTRSKLSGLAPPEKSTEESSESSDEDLPSGQAIKSPPISVNPNRGPAAPVPTPEQHQAVNTRKAQASGSTAQSSSSESEDEDMIPATQPPTLAIRTNVTTPTALSQTAAQPSKSEQSSRMPKGKKPKTASTQISSAMEALPVTLPQSTPAQSKTTNKLGDPKLAEKQQLTPGYPKAPRSSEDSSDTSSESEEDAKRPQMSKSSQRLDPDASQKETVVEETPTESSDDEMVAPSQSLLSGYVTPGLTVANSQPSKATPRPDANPLVSSAPATKDNPDGKQKSKSQDSTADTTLRKTGRKEASSGSTPQKPKKPKKSTLSSPAPAQTLPNSITQRLLEQPWPLSEAQVQASVMKVLTELLEQERQKATEAIKESGKKGQKRKLSGDQVEAGAPKNKKKKQQLAAGTSAGSPEKASRTSKAKSKLNKGSAGGKGKGSPVPQGAKEKPEGKLGIKLESGEQSDPKSKKEKKKSSKKKKDKEKKEKKKGKKTPAKDSASPVQKKKKKKKKTAEPAV", "length": 1357 }, "evidence": [ { "id": "A0A5G2R8J0", "url": "https://omabrowser.org/oma/group/A0A5G2R8J0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BHU1-1", "protein_name": "Treacle ribosome biosis factor 1", "gene_name": "TCOF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEARKRRELLPLIYQHLLQAGYVRAAREVKEQSGQKIFLSQPVTLLDIYTHWQQTSEIGRKRKAEEDAALQAKRSRVSDPISSSESSEEEEEEEEAEAKTTKPTPRLAATNSSVTGTVSSSNVKEKAKAKTTKASKTVNSTTHPAPGKAVAHLLTGKSPQKTSGPSANAVLVSETEEEGSVSALRTATTPGMASADQADSSSEDTTSSSDETDLEAKAAVKPLQVRASATAVKESPRKSAAPTPGKAGVVTPQVRGGAVTPASRAKKPEEVSESSEESDESEEAAPAGTPSQVKALEKTVPIRVAPSPAKGTPGKGATPAPPGKAGPLGKPEEDSESSSEESDSEEETQAVKTPVQAKPSGKIPQVKAASTPKIQVFFPKKGSPPTSPGKAGPAATQAQPRKQEEEESSSSSSKESDSEGEVPTAMQQTTSLAQAKPLEKNSQVRAASATGAGPSAKGTVPALPQKARSVAAQDGKQEDSESSSEEESDSEEEMQKAGTSAQAQSSGKALQIRPASGPTKRPPQKAGPATTQVKVERAEEDSESSEEESDSEDEAPVAKTPAQAKSAVKTSQIKASPRKGTPITPSSARVPPVQVGTPAPRTAAAVSTPTCASSPAIVRHTQKPGEDSSSSEESESEEETAPAAAGGQMKSIGKTLPVKAASPATKGPSGKGTTPGPPGKAGPAVAQVKAEVQEDSESSEESDNEEAAATPAQVKTSVKTPQTKANSSATRVASAKAAAPAPGKGGLAVAQAKVGSPAKVKPPARTPQSSAVSGRGQVSVPAVGKAAAAAAQAQPGPVKGSQEDSESSEEESDSEGEAPPQGKPSGKTPQVRTASAPTKASPKKGAAPVPPGKAGPPATQAKRQEEDSESSSEEESDSDGDVPAAAPPAQKEGSSKTATSKTLAPASLEKKAEESSTSSDEDLPSSQVIKTPLIFVDPNRSPAGPAATPAQAQATGTLRKAQALESTARSSSESEDEDVIPATQCPTPATRTSVVTVPTAPPKAALRASVVGAPSSEDTSQGSEGKKQEASATQVTKRNLPLTQAALKVLAQKASEAQSPAAKTPSSSGTDSAVGTLSTASPQSTPTQVRMANKLRKPEVPTAQQATATPSGHPTAKAPATSDDSNSSSSGSEDDAKGSQAAPSAHRPGPAPSRRETLVEETTTESSDDEVVAPSQSLLSGFVTPGLTPAGSKTSKAAPKPDASPSVSSTPATRDAPEGKQEVEPQQAAGTMSPKTGRKEAGATPQKPGKGLGSPPASMLALQSNITQRLLSEPWPLSEAQVQASVAKVLTELLEQERKKAMDTAKEGSRKGRLGHKRKLSEDQTAPKAPKNKKKKQLAAADGGEHVVSSEKAPRTVKGKSKKDRASGDVKEKKEKESPGSQGAKEKPVGELGTPKGDGGDHGNLKMKKEKKKSDKKKKDKEKKEKKKKAKKASTKDPGSPSQKKKKRKKKTAEQTV", "length": 1458 }, "evidence": [ { "id": "A0A5G2R8J0", "url": "https://omabrowser.org/oma/group/A0A5G2R8J0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O08784-1", "protein_name": "Treacle protein", "gene_name": "Tcof1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEARKRRELLPLIYHHLLQAGYVRAAREVKEQSGQKSFLTQPVTLLDIYTHWQQTSELGQKQKAEDDETLQAKKSRVSDPVSSSESSDQEKEEEAATERAKATPRPTPVNSATAALPSKVKEKGKTKTANKTVNSVSHPGSGKTVVHLLSGKSPKKSAEPLANTVLASETEEEGNAQALGPTAKSGTVSAGQGSSSSEDSSISSDETDVEVKSPAKPAQAKASAAPAKDPPARTAPGPTKLGNVAPTPAKPARAAAAAAAAAVAAAAAAAAEESESSEEDSDSEDEAPAGLPSQVKASGKGPHVRADSVSAKGISGKGPILATPGKTGPAATQAKAERPEKDSETSSEDDSDSEDEMPVTVNTPQARTSGKSPRARGTSAPAKESSQKGAPAVTPGKARPVAAQAGKPEAKSSEESESDSGETPAAATLTTSPAKVKPLGKSSQVRPVSTVTPGSSGKGANLPCPGKVGSAALRVQMVKKEDVSESSSAELDSDGPGSPAKAKASLALPQKVRPVATQVKTDRGKGHSGSSEESSDSEEEAAPAASAAQAKPALEKQMKASSRKGTPASATGASTSSHCKAGAVTSSASLSSPALAKGTQRSDVDSSSESESEGAAPSTPRVQGKSGGKGLQGKAALGQGVAPVHTQKTGPSVKAMAQEDSESLEEDSSSEEEDETPAQATPLGRLPQAKANPPPTKTPPASASGKAVAAPTKGKPPVPNSTVSARGQRSVPAAGKAGAPATQAQKGPVAGTGEDSESSSKEESDSEEETPAQIKPVGKTSQVRAASAPAKESPKKGAHPGTPGKTGSSATQAQPGKTEDSDSSSEESDSDTEMPSAQAIKSPPVSVNRNSSPAVPAPTPEGVQAVNTTKKASGTTAQSSSSESEDGDEDLIPATQPSTYALRTSVTTPAALSRAASQPSKSEQSSRMPKGKKAKAAASAQTSSAVETLPMMPPQSAPIQPKATNKLGKSKLPEKQQLAPGYPKAPRSSEDSSDTSSEDEEDAKRPQMPKSAHRLDPDPSQKETVVEETPTESSEDEMVAPSQSLLSGYMTPGLTVANSQASKATPRPDSNSLASSAPATKDNPDGKQKSKSQHAADTALPKTGRKEASSGSTPQKPKKLKKSTSSSPAPTQTLPNSITQRLLEQAWPLSEAQVQASVVKVLTELLEQERLKATEAIKESGKKSQKRKLSGDLEAGAPKNKKKKEQPVPRASAVSPEKAPMTSKAKSKLDKGSAGGKGKGSPGPQGAKEKPDGELLGIKLESGEQSDPKSKSKKKKSLKKKKDKEKKEKKKGKKSLAKDSASPIQKKKKKKKKSAEPAV", "length": 1320 }, "evidence": [ { "id": "A0A5G2R8J0", "url": "https://omabrowser.org/oma/group/A0A5G2R8J0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q13428-1", "protein_name": "Treacle protein", "gene_name": "TCOF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV", "length": 1488 }, "evidence": [ { "id": "A0A5G2R8J0", "url": "https://omabrowser.org/oma/group/A0A5G2R8J0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "neural crest formation", "id": "GO:0014029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014029", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0" } ], "pmid": "" }, { "name": "neural crest cell development", "id": "GO:0014032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014032", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0" } ], "pmid": "" }, { "name": "nucleolar large rRNA transcription by RNA polymerase I", "id": "GO:0042790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042790", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0" } ], "pmid": "" }, { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 877, "end_pos": 879, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J0" }, { "id": "PF03546", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03546" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Treacle protein", "eco_id": "ECO_0000259", "start_pos": 336, "end_pos": 645, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 262, 308, 585, 1118 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 877, "end_pos": 879 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9E9-1", "uniprot_ac": "A0A5G2R9E9", "uniprot_id": "A0A5G2R9E9_PIG", "mass": { "chemical_mass": 63699.0, "monoisotopic_mass": 63699.0 }, "refseq": {}, "gene_names": [ { "name": "MCOLN3", "type": "recommended", "evidence": [ { "id": "A0A5G2R9E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9" } ] } ], "protein_names": [ { "name": "Mucolipin TRP cation channel 3", "type": "synonym", "evidence": [ { "id": "A0A5G2R9E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9E9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MCOLN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9", "locus": { "chromosome": "4", "start_pos": 130865904, "end_pos": 130838291, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000023745", "url": "https://www.ensembl.org/id/ENSSSCG00000023745" } ] } } ], "crossref": [ { "id": "A0A5G2R9E9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9E9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000023745", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000023745", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21072", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21072", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR013122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12127:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12127:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21381", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21381", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R4J8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9E9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L663", "url": "https://www.uniprot.org/uniprotkb/I3L663", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L663-1", "url": "https://www.uniprot.org/uniprotkb/I3L663-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADPEPVISSCSSREEENRCTFNQHTCPSEERLLEDQMRRKLKFFFMTPCEKFWTRGRKPWKLAMQVLKIAMVTIQLIFFGLSNQMVVAFKEENTIAFKHLFLKGYVDRDDTYAVYTQSDVYDRIVFAVNQYLQLRSISVGNHAYENKGAEQSAMAICWHFYKQGNICPGNDTFDVDPEVKTECFFVEPDEAVDTGTLEENKLNLTLDFHRLLTVELQFKLKAINLQTIRHHELPDCYDFTLTITFDNRAHSGRIKISLENDISIRECKDWHVSGSIQKNTRYMMIFDAFVLLTCLASLTLCARSVVRGLQLQQEFANFFLLHYKKEVSVSDRMEFVNGWYIMIIISDILTVIGSILKMEIQAKSLMSYGVCSILLGASTLLVWLGALRYLSFFPKYNLLILTLQAALPSVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNVVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKHYQEDGFPETELRTFISECKDEPKSGEDRLEDGPPVSTGRLSP", "length": 551, "header": "tr|A0A5G2R9E9-1|A0A5G2R9E9_PIG Isoform 1 of Mucolipin TRP cation channel 3 OS=Sus scrofa OX=9823 GN=MCOLN3 PE=4 SV=1 CANONICAL=A0A5G2R9E9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R4J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9/entry#A0A5G2R4J8-1", "sequence": { "sequence": "MADPEPVISSCSSREEENRCTFNQHTCPSEERLLEDQMRRKLKFFFMTPCEKFWTRGRKPWKLAMQVLKIAMVTIQLIFFGLSNQMVVAFKEENTIAFKHLFLKGYVDRDDTYAVYTQSDVYDRIVFAVNQYLQLRSISVGNHAYENKGAEQSAMAICWHFYKQGNICPGNDTFDVDPEVKTECFFVEPDEAVDTGTLEENKLNLTLDFHRLLTVELQFKLKAINLQTIRHHELPDCYDFTLTITFDNRAHSGRIKISLENDISIRECKDWHVSGSIQKNTRYMMIFDAFVLLTCLASLTLCARSVVRGLQLQQVGAAFS", "length": 320, "header": "tr|A0A5G2R4J8-1|A0A5G2R9E9_PIG Computationally mapped isoform of Mucolipin TRP cation channel 3 OS=Sus scrofa OX=9823 GN=MCOLN3 PE=4 SV=1 CANONICAL=A0A5G2R9E9-1" }, "locus": { "chromosome": "4", "start_pos": 130858459, "end_pos": 130838294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086534.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086534.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072133.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072133.1" } ] } }, { "isoform_ac": "A0A5G2R9E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9/entry#A0A5G2R9E9-1", "sequence": { "sequence": "MADPEPVISSCSSREEENRCTFNQHTCPSEERLLEDQMRRKLKFFFMTPCEKFWTRGRKPWKLAMQVLKIAMVTIQLIFFGLSNQMVVAFKEENTIAFKHLFLKGYVDRDDTYAVYTQSDVYDRIVFAVNQYLQLRSISVGNHAYENKGAEQSAMAICWHFYKQGNICPGNDTFDVDPEVKTECFFVEPDEAVDTGTLEENKLNLTLDFHRLLTVELQFKLKAINLQTIRHHELPDCYDFTLTITFDNRAHSGRIKISLENDISIRECKDWHVSGSIQKNTRYMMIFDAFVLLTCLASLTLCARSVVRGLQLQQEFANFFLLHYKKEVSVSDRMEFVNGWYIMIIISDILTVIGSILKMEIQAKSLMSYGVCSILLGASTLLVWLGALRYLSFFPKYNLLILTLQAALPSVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNVVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKHYQEDGFPETELRTFISECKDEPKSGEDRLEDGPPVSTGRLSP", "length": 551, "header": "tr|A0A5G2R9E9-1|A0A5G2R9E9_PIG Isoform 1 of Mucolipin TRP cation channel 3 OS=Sus scrofa OX=9823 GN=MCOLN3 PE=4 SV=1 CANONICAL=A0A5G2R9E9-1" }, "locus": { "chromosome": "4", "start_pos": 130864900, "end_pos": 130838294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085422.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085422.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070749.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070749.1" } ] } }, { "isoform_ac": "I3L663-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9/entry#I3L663-1", "sequence": { "sequence": "MADPEPVISSCSSREEENRCTFNQHTCPSEERLLEDQMRRKLKFFFMTPCEKFWTRGRKPWKLAMQVLKIAMVTIQYLQLRSISVGNHAYENKGAEQSAMAICWHFYKQGNICPGNDTFDVDPEVKTECFFVEPDEAVDTGTLEENKLNLTLDFHRLLTVELQFKLKAINLQTIRHHELPDCYDFTLTITFDNRAHSGRIKISLENDISIRECKDWHVSGSIQKNTRYMMIFDAFVLLTCLASLTLCARSVVRGLQLQQEFANFFLLHYKKEVSVSDRMEFVNGWYIMIIISDILTVIGSILKMEIQAKSLMSYGVCSILLGASTLLVWLGALRYLSFFPKYNLLILTLQAALPSVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNVVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKHYQEDGFPETELRTFISECKDEPKSGEDRLEDGPPVSTGRLSP", "length": 496, "header": "tr|I3L663-1|A0A5G2R9E9_PIG Computationally mapped isoform of Mucolipin TRP cation channel 3 OS=Sus scrofa OX=9823 GN=MCOLN3 PE=4 SV=3 CANONICAL=A0A5G2R9E9-1" }, "locus": { "chromosome": "4", "start_pos": 130864900, "end_pos": 130838294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022578.4", "url": "https://www.ensembl.org/id/ENSSSCT00000022578.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019514.3", "url": "https://www.ensembl.org/id/ENSSSCP00000019514.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R4J8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4J8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9E9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9" } ], "pmid": "" }, { "name": "NAADP-sensitive calcium-release channel activity", "id": "GO:0072345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072345", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9E9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9E9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9E9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9E9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9E9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 551, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9E9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9E9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9" }, { "id": "PF21381", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21381" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mucolipin extracytosolic", "eco_id": "ECO_0000259", "start_pos": 87, "end_pos": 269, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R9E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9E9" }, { "id": "PF08016", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Polycystin cation channel PKD1/PKD2", "eco_id": "ECO_0000259", "start_pos": 372, "end_pos": 507, "start_aa": "Cys", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 204, "end_pos": 206 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RC75-1", "uniprot_ac": "A0A5G2RC75", "uniprot_id": "A0A5G2RC75_PIG", "mass": { "chemical_mass": 59093.0, "monoisotopic_mass": 59093.0 }, "refseq": {}, "gene_names": [ { "name": "SMARCD2", "type": "recommended", "evidence": [ { "id": "A0A5G2RC75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75" } ] } ], "protein_names": [ { "name": "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2", "type": "synonym", "evidence": [ { "id": "A0A5G2RC75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SMARCD2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75", "locus": { "chromosome": "12", "start_pos": 15101899, "end_pos": 15091729, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000041822", "url": "https://www.ensembl.org/id/ENSSSCG00000041822" } ] } } ], "crossref": [ { "id": "A0A5G2RC75", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC75", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041822", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041822", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17675", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17675", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13844", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13844", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3214858", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214858", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939243", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9933939", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9933939", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9933946", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9933946", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9933947", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9933947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R573", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R573", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R573-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R573-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RC75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RC75-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1L4A5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1L4A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1L4A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1L4A5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGRGAGGFPLPPLSPGGGAVAAALGAPPPPAGPGMLPGPALRGPGPAGGVGGPGAAAFRLTYAPPLAHFLQRPGMSPGSRMPMAGLQVGPPAGSPFGTAAPLRPGMPPTMMDPFRKRLLVPQAQPPMPAQRRGLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEGDSAGSAGTPGGTPAGDKVASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMPTTQETDGFQVKRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPDPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQQRRQELEQVLGIRLT", "length": 531, "header": "tr|A0A5G2RC75-1|A0A5G2RC75_PIG Isoform 1 of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 OS=Sus scrofa OX=9823 GN=SMARCD2 PE=3 SV=2 CANONICAL=A0A5G2RC75-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R573-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75/entry#A0A5G2R573-1", "sequence": { "sequence": "MSGRGAGGFPLPPLSPGGGAAFRPMGPAGPAAQYQRPGMSPGSRMPMAGLQVGPPAGSPFGTAAPLRPGMPPTMMDPFRKRLLVPQAQPPMPAQRRGLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEGDSAGSAGTPGGTPAGDKVASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMPTTQETDGFQVKRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPDPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQQRRQELEQVLGIRLT", "length": 494, "header": "tr|A0A5G2R573-1|A0A5G2RC75_PIG Computationally mapped isoform of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 OS=Sus scrofa OX=9823 GN=SMARCD2 PE=3 SV=1 CANONICAL=A0A5G2RC75-1" }, "locus": { "chromosome": "12", "start_pos": 15100994, "end_pos": 15092002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076519.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076519.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071469.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071469.1" } ] } }, { "isoform_ac": "A0A5G2RC75-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75/entry#A0A5G2RC75-1", "sequence": { "sequence": "MSGRGAGGFPLPPLSPGGGAVAAALGAPPPPAGPGMLPGPALRGPGPAGGVGGPGAAAFRLTYAPPLAHFLQRPGMSPGSRMPMAGLQVGPPAGSPFGTAAPLRPGMPPTMMDPFRKRLLVPQAQPPMPAQRRGLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEGDSAGSAGTPGGTPAGDKVASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMPTTQETDGFQVKRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPDPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQQRRQELEQVLGIRLT", "length": 531, "header": "tr|A0A5G2RC75-1|A0A5G2RC75_PIG Isoform 1 of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 OS=Sus scrofa OX=9823 GN=SMARCD2 PE=3 SV=2 CANONICAL=A0A5G2RC75-1" }, "locus": { "chromosome": "12", "start_pos": 15100994, "end_pos": 15092002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076875.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076875.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071817.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071817.2" } ] } }, { "isoform_ac": "A0A8D1L4A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75/entry#A0A8D1L4A5-1", "sequence": { "sequence": "MTKGAGVTPTWAPRRCWGAGPRPGMSPGSRMPMAGLQVGPPAGSPFGTAAPLRPGMPPTMMDPFRKRLLVPQAQPPMPAQRRGLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEGDSAGSAGTPGGTPAGDKVASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMPTTQETDGFQVKRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPDPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQQRRQELEQVLGIRLT", "length": 480, "header": "tr|A0A8D1L4A5-1|A0A5G2RC75_PIG Computationally mapped isoform of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 OS=Sus scrofa OX=9823 GN=SMARCD2 PE=3 SV=1 CANONICAL=A0A5G2RC75-1" }, "locus": { "chromosome": "12", "start_pos": 15100994, "end_pos": 15095717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076973.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076973.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061103.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061103.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 217, "start_aa": "Thr", "end_pos": 217, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr217", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 221, "start_aa": "Thr", "end_pos": 221, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr221", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R573", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R573" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3214858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214858", "resource": "Reactome", "description": "RMTs methylate histone arginines" }, { "id": "R-SSC-8939243", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" }, { "id": "R-SSC-9933939", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9933939", "resource": "Reactome", "description": "Formation of the polybromo-BAF (pBAF) complex" }, { "id": "R-SSC-9933946", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9933946", "resource": "Reactome", "description": "Formation of the embryonic stem cell BAF (esBAF) complex" }, { "id": "R-SSC-9933947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9933947", "resource": "Reactome", "description": "Formation of the non-canonical BAF (ncBAF) complex" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75" } ], "pmid": "" }, { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RC75-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 531, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RC75-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC75" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RC75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC75" }, { "id": "PS51925", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51925" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DM2", "eco_id": "ECO_0000259", "start_pos": 306, "end_pos": 383, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 217, 221 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R670-1", "uniprot_ac": "A0A5G2R670", "uniprot_id": "A0A5G2R670_PIG", "mass": { "chemical_mass": 36322.0, "monoisotopic_mass": 36322.0 }, "refseq": { "ac": "XP_020937088", "name": "olfactory receptor 4S2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937088" }, "gene_names": [ { "name": "LOC110258240", "type": "recommended", "evidence": [ { "id": "A0A5G2R670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670" } ] }, { "name": "LOC110258240", "type": "synonym", "evidence": [ { "id": "XP_020937088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937088" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4S2-like", "type": "synonym", "evidence": [ { "id": "XP_020937088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937088" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R670", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R670", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110258240", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670", "locus": {} } ], "crossref": [ { "id": "A0A5G2R670", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R670", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110258240", "url": "https://www.ncbi.nlm.nih.gov/gene/110258240", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110258240", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258240", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R670", "url": "https://www.orthodb.org/?gene=A0A5G2R670", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020937088", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937088", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R670", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R670-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEISNVTEFVFWGLSQNLKVEKVCLVVFSFFYSVILLGNLLIMLTVYVGNLSKSPMYFFLSYLSFVDICYSSAIAPRMMVDLLAKTKTISYVGCMLQLFVAHFLGCTEIFILTVMAYDRYVAICKPLHYMTIMDRERCNKMLLGTWLGGFLHSIVQVALVVQLPFCGPNEIDHYFCDIHPLLKLACTDTYVVGVVVIANSGIITLVSFVILLFSYILILVFLRKQSAEGRRKALSTCGSHIAVVIIFFGPCTFMYMRPKTTFSEDKMVALFYTIISPMLNPLIYTLRNAEVKNAMKKLWGRWVFWGAKGKELEVTIQGG", "length": 320, "header": "tr|A0A5G2R670-1|A0A5G2R670_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258240 PE=3 SV=1 CANONICAL=A0A5G2R670-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R670-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670/entry#A0A5G2R670-1", "sequence": { "sequence": "MEEISNVTEFVFWGLSQNLKVEKVCLVVFSFFYSVILLGNLLIMLTVYVGNLSKSPMYFFLSYLSFVDICYSSAIAPRMMVDLLAKTKTISYVGCMLQLFVAHFLGCTEIFILTVMAYDRYVAICKPLHYMTIMDRERCNKMLLGTWLGGFLHSIVQVALVVQLPFCGPNEIDHYFCDIHPLLKLACTDTYVVGVVVIANSGIITLVSFVILLFSYILILVFLRKQSAEGRRKALSTCGSHIAVVIIFFGPCTFMYMRPKTTFSEDKMVALFYTIISPMLNPLIYTLRNAEVKNAMKKLWGRWVFWGAKGKELEVTIQGG", "length": 320, "header": "tr|A0A5G2R670-1|A0A5G2R670_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258240 PE=3 SV=1 CANONICAL=A0A5G2R670-1" }, "locus": { "chromosome": "AEMK02000493.1", "start_pos": 70216, "end_pos": 69257, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084553.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084553.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071840.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071840.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R670", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110258240", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258240", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R670", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R670", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R670", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R670-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R670-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R670" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R670" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 51, "end_pos": 53 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R6A4-1", "uniprot_ac": "A0A5G2R6A4", "uniprot_id": "A0A5G2R6A4_PIG", "mass": { "chemical_mass": 35766.0, "monoisotopic_mass": 35766.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R6A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6A4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6A4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6A4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6A4", "locus": {} } ], "crossref": [ { "id": "A0A5G2R6A4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6A4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156339", "url": "https://www.ncbi.nlm.nih.gov/gene/100156339", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156339", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156339", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VWPFPST", "url": "https://omabrowser.org/oma/group/VWPFPST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R6A4", "url": "https://www.orthodb.org/?gene=A0A5G2R6A4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R6A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6A4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTKPKEGENNSVVSEFVFLGITNSWEIQLLLSVFTSTFYVASMMGNSLIMLTVTSDPHLHSPMYFLLANLSFIDMGVSSVTSPKMIYDLFRKRKVISFSGCITQIFFIHVIGGVEMVLLIAMAFDRYVAICKPLHYLTIMSPRLCIFLLVAAWIIGLVHSTVQLASVVNLPFCGPNVLDSFYCDLPRFIKLACVDTDQLEFMVTANSGLISVGSFFILIISYIVIILTVKKQCSVGSSKALSTLSAHITVVILFFGPLIFFYMWPFPSTPLDKFLAIFDAVLTPSLNPIIYTFRNQEMKVSMRRVCRQLVNYRRSLK", "length": 318, "header": "tr|A0A5G2R6A4-1|A0A5G2R6A4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R6A4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R6A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6A4/entry#A0A5G2R6A4-1", "sequence": { "sequence": "MSTKPKEGENNSVVSEFVFLGITNSWEIQLLLSVFTSTFYVASMMGNSLIMLTVTSDPHLHSPMYFLLANLSFIDMGVSSVTSPKMIYDLFRKRKVISFSGCITQIFFIHVIGGVEMVLLIAMAFDRYVAICKPLHYLTIMSPRLCIFLLVAAWIIGLVHSTVQLASVVNLPFCGPNVLDSFYCDLPRFIKLACVDTDQLEFMVTANSGLISVGSFFILIISYIVIILTVKKQCSVGSSKALSTLSAHITVVILFFGPLIFFYMWPFPSTPLDKFLAIFDAVLTPSLNPIIYTFRNQEMKVSMRRVCRQLVNYRRSLK", "length": 318, "header": "tr|A0A5G2R6A4-1|A0A5G2R6A4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R6A4-1" }, "locus": { "chromosome": "7", "start_pos": 79224741, "end_pos": 79223788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082365.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082365.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071875.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071875.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6A4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156339", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156339", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LKR6-1", "protein_name": "Olfactory receptor", "gene_name": "OR4F14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYGANHSVVLEFVFLGITNSWEIQLLLFVFSSIFFMASIMGNSLIILTVTSDPHLHSPMYFLLANLSFIDMGVSSVSSPKMIYDLFRKHKVISFSGCIAQIFFIHVIGGVEMVLLIAMAFDRYIAICKPLHYLTIMSPRMCVFFLVSAWMIGLMHSMVQLAFVVNLPFCGPNVLDSFYCDLPRFIKLACIDTYQLEFMVTANSGFISVGSFFILIISYIVIILTVQKHSSGGSSKALSTLSAHITVVVLFFGPLIFFYVWPFPSTHLDKFLAFFDAVLTPFLNPVIYTFRNQEMKMAMRRVCQQLVNNKRSLE", "length": 313 }, "evidence": [ { "id": "A0A5G2R6A4", "url": "https://omabrowser.org/oma/group/A0A5G2R6A4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VF10-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNQSVVSEFVFLGLTNSWNIQLFLFVFSSIFYVASMMGNSLIVFTVVSDSHLHSPMYFLLANLSFIDLGISSVTSPKMICDLFRKHKVISFRGCVTQIFFIHVIGGVEMVLLIAMAFDRYVAICKPLHYLTIMSPRVCILFSVASWVVGFMHSLVQLAFVVNLPFCGPNVLDSFYCDFPRFIKLACTDTYKLELLVSINSGFMSVGSFFILIISYIVIIFTVQKHSSSGSSKALSTLSAHVTVVVLFFGPVMFFYTWPSSYTHLDKFLAIFDAIVTPFLNPVIYTLRNQEMKIAMMRVFSKLMGCRQIFKHLNFEQT", "length": 317 }, "evidence": [ { "id": "A0A5G2R6A4", "url": "https://omabrowser.org/oma/group/A0A5G2R6A4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6A4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6A4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6A4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6A4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R6A4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 318, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R6A4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6A4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R6A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6A4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 292, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R6B3-1", "uniprot_ac": "A0A5G2R6B3", "uniprot_id": "A0A5G2R6B3_PIG", "mass": { "chemical_mass": 89172.0, "monoisotopic_mass": 89172.0 }, "refseq": {}, "gene_names": [ { "name": "ZFYVE28", "type": "recommended", "evidence": [ { "id": "A0A5G2R6B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3" } ] } ], "protein_names": [ { "name": "Lateral signaling target protein 2 homolog", "type": "recommended", "evidence": [ { "id": "A0A5G2R6B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger FYVE domain-containing protein 28", "type": "synonym", "evidence": [ { "id": "A0A5G2R6B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6B3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3#function" }, { "database": "UniProtKB", "id": "ARBA00059106", "url": "https://www.uniprot.org/uniprotkb/ARBA00059106#function" }, { "database": "UniProtKB", "id": "F1S8Q3", "url": "https://www.uniprot.org/uniprotkb/F1S8Q3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6B3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZFYVE28", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3", "locus": { "chromosome": "8", "start_pos": 1225429, "end_pos": 1312521, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008689", "url": "https://www.ensembl.org/id/ENSSSCG00000008689" } ] } } ], "crossref": [ { "id": "A0A5G2R6B3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6B3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008689", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008689", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15731", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15731", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051118", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051118", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46465:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46465:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R6B3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S8Q3", "url": "https://www.uniprot.org/uniprotkb/F1S8Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S8Q3-1", "url": "https://www.uniprot.org/uniprotkb/F1S8Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMNRFRKWLYKPKDNVLNIINQIMDVCIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGALRDQALRDLNTYTEKMREALRHFDVLFAEFELSYVSAMVPVKSPREYYVQQEVIVLFCETVERALDFGYLTQDMIDDYEPALMFTIPRLAIVCGLVVYADGPLNLDRKAEDMSELFRPFHTLLRKIRDLLQTLTEEELHTLERNLCISQEVEFPIRADAQVPPALAPAFPEPLAPEELLADKPKNSEAELACSMQYDDQELEQLSRLVHKAGDEMSSLLSPPSATQSPAHRLGATGSPGPASPGSARLPQGSDDEEGRVFFMDDVGGAAEARGSPSGQAGSASADPQERGPGGESRERGASTPADAGKGGGNDNNNVEGDGARAGGPNSCSCLDSRPHLDGWEVSSDAAETAELIAHRTGGMKLSATVIFNPKSPASLDSTLASAEVPGDGFSPSEPAAEGTDGGPHKLSATAADCLLNSCVCCGGCGGGREDAAESLRGKCGSGSVISSSHVGLAKASAKGAAPGLPEAGPALEALPSEDAPGLQEPKAPTPNKCLTHTSGPPGDAADGLPGGGDGASQPTEERRPGGAAEEQPQRLLVPSSSTADSCPSDKSGPDAAPVATREKIRSRFHGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFQVMATKPETDDKEKLKKVTQTLRSAALEDCALCQETLSSSELATKTRDGGLEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSPHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKAGI", "length": 832, "header": "tr|A0A5G2R6B3-1|A0A5G2R6B3_PIG Isoform 1 of Lateral signaling target protein 2 homolog OS=Sus scrofa OX=9823 GN=ZFYVE28 PE=3 SV=2 CANONICAL=A0A5G2R6B3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R6B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3/entry#A0A5G2R6B3-1", "sequence": { "sequence": "MMNRFRKWLYKPKDNVLNIINQIMDVCIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGALRDQALRDLNTYTEKMREALRHFDVLFAEFELSYVSAMVPVKSPREYYVQQEVIVLFCETVERALDFGYLTQDMIDDYEPALMFTIPRLAIVCGLVVYADGPLNLDRKAEDMSELFRPFHTLLRKIRDLLQTLTEEELHTLERNLCISQEVEFPIRADAQVPPALAPAFPEPLAPEELLADKPKNSEAELACSMQYDDQELEQLSRLVHKAGDEMSSLLSPPSATQSPAHRLGATGSPGPASPGSARLPQGSDDEEGRVFFMDDVGGAAEARGSPSGQAGSASADPQERGPGGESRERGASTPADAGKGGGNDNNNVEGDGARAGGPNSCSCLDSRPHLDGWEVSSDAAETAELIAHRTGGMKLSATVIFNPKSPASLDSTLASAEVPGDGFSPSEPAAEGTDGGPHKLSATAADCLLNSCVCCGGCGGGREDAAESLRGKCGSGSVISSSHVGLAKASAKGAAPGLPEAGPALEALPSEDAPGLQEPKAPTPNKCLTHTSGPPGDAADGLPGGGDGASQPTEERRPGGAAEEQPQRLLVPSSSTADSCPSDKSGPDAAPVATREKIRSRFHGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFQVMATKPETDDKEKLKKVTQTLRSAALEDCALCQETLSSSELATKTRDGGLEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSPHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKAGI", "length": 832, "header": "tr|A0A5G2R6B3-1|A0A5G2R6B3_PIG Isoform 1 of Lateral signaling target protein 2 homolog OS=Sus scrofa OX=9823 GN=ZFYVE28 PE=3 SV=2 CANONICAL=A0A5G2R6B3-1" }, "locus": { "chromosome": "8", "start_pos": 1312521, "end_pos": 1226542, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069559.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069559.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072619.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072619.2" } ] } }, { "isoform_ac": "F1S8Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3/entry#F1S8Q3-1", "sequence": { "sequence": "MDVCIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGALRDQALRDLNTYTEKMREALRHFDVLFAEFELSYVSAMVPVKSPREYYVQQEVIVLFCETVERALDFGYLTQDMIDDYEPALMFTIPRLAIVCGLVVYADGPLNLDRKAEDMSELFRPFHTLLRKIRDLLQTLTEEELHTLERNLCISQEVEFPIRADAQVPPALAPAFPEPLAPEELLADKPKNSEAELACSMQYDDQELEQLSRLVHKAGDEMSSLLSPPSATQSPAHRLGATGSPGPASPGSARLPQGSDDEEGRVFFMDDVGGAAEARGSPSGQAGSASADPQERGPGGESRERGASTPADAGKGGGNDNNNVEGDGARAGGPNSCSCLDSRPHLDGWEVSSDAAETAELIAHRTGGMKLSATVIFNPKSPASLDSTLASAEVPGDGFSPSEPAAEGTDGGPHKLSATAADCLLNSCVCCGGCGGGREDAAESLRGKCGSGSVISSSHVGLAKASAKGAAPGLPEAGPALEALPSEDAPGLQEPKAPTPNKCLTHTSGPPGDAADGLPGGGDGASQPTEERRPGGAAEEQPQRLLVPSSSTADSCPSDKSGPDAAPVATREKIRSRFHGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFQVMATKPETDDKEKLKKVTQTLRSAALEDCALCQETLSSSELATKTRDGGLEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSPHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKAGI", "length": 809, "header": "tr|F1S8Q3-1|A0A5G2R6B3_PIG Computationally mapped isoform of Lateral signaling target protein 2 homolog OS=Sus scrofa OX=9823 GN=ZFYVE28 PE=3 SV=5 CANONICAL=A0A5G2R6B3-1" }, "locus": { "chromosome": "8", "start_pos": 1260333, "end_pos": 1226542, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009506.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009506.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009262.5", "url": "https://www.ensembl.org/id/ENSSSCP00000009262.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S8Q3", "url": "https://www.uniprot.org/uniprotkb/F1S8Q3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6B3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6B3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6B3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6B3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042059", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6B3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R6B3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 832, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R6B3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6B3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R6B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6B3" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 762, "end_pos": 818, "start_aa": "Asp", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R6C2-1", "uniprot_ac": "A0A5G2R6C2", "uniprot_id": "A0A5G2R6C2_PIG", "mass": { "chemical_mass": 36107.0, "monoisotopic_mass": 36107.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R6C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2", "locus": {} } ], "crossref": [ { "id": "A0A5G2R6C2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6C2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000046786", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000046786", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF424", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF424", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R6C2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LRDQVHYMASPGNHSSAPVSEFLLICFPNYQSWQHWLSLPLSLLFLLAMGANATLLVTIRLEASLHQPMYYLLSLLSLLDMVLCLTVIPKVLAIFWFDLRAISFFACFLQMFIMNSFLTMESCTFMVMAYDRYVAICHPLRYPSIITDQFVARAAIFVVARNGLFSLPVPVLSSRLRYCAEKVIQNCICTNLSVSKLSCDDITFNRLYQFVAGWTLLGSDLVLVVLSYSFILKAVLRLRAEGAATKALSTCGSHLILILFFSTVLLVLVITNLARRRIPPDVPILLNILHHLIPPALNPIVYGVRTKEVKQGIQKLLSRF", "length": 320, "header": "tr|A0A5G2R6C2-1|A0A5G2R6C2_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2R6C2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R6C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2/entry#A0A5G2R6C2-1", "sequence": { "sequence": "LRDQVHYMASPGNHSSAPVSEFLLICFPNYQSWQHWLSLPLSLLFLLAMGANATLLVTIRLEASLHQPMYYLLSLLSLLDMVLCLTVIPKVLAIFWFDLRAISFFACFLQMFIMNSFLTMESCTFMVMAYDRYVAICHPLRYPSIITDQFVARAAIFVVARNGLFSLPVPVLSSRLRYCAEKVIQNCICTNLSVSKLSCDDITFNRLYQFVAGWTLLGSDLVLVVLSYSFILKAVLRLRAEGAATKALSTCGSHLILILFFSTVLLVLVITNLARRRIPPDVPILLNILHHLIPPALNPIVYGVRTKEVKQGIQKLLSRF", "length": 320, "header": "tr|A0A5G2R6C2-1|A0A5G2R6C2_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2R6C2-1" }, "locus": { "chromosome": "9", "start_pos": 3756448, "end_pos": 3755315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068031.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068031.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066140.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066140.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6C2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R6C2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R6C2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6C2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R6C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6C2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 302, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 }, { "start_pos": 191, "end_pos": 193 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R6H6-1", "uniprot_ac": "A0A5G2R6H6", "uniprot_id": "A0A5G2R6H6_PIG", "mass": { "chemical_mass": 39054.0, "monoisotopic_mass": 39054.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Cell cycle control protein 50C", "type": "recommended", "evidence": [ { "id": "A0A5G2R6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein 30C", "type": "synonym", "evidence": [ { "id": "A0A5G2R6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6H6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6", "locus": {} } ], "crossref": [ { "id": "A0A5G2R6H6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6H6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011967", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011967", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR005045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NDIFWLH", "url": "https://omabrowser.org/oma/group/NDIFWLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10926", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10926", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10926:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10926:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03381", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03381", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R6H6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SKZ4", "url": "https://www.uniprot.org/uniprotkb/F1SKZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SKZ4-1", "url": "https://www.uniprot.org/uniprotkb/F1SKZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRKSQDSQSRLPDNTAVKQQQLPAYRLQLSAKEILSGFFATGVFCLGIGIILLLSAKSIKEIEINYTEKCANCAKLRENAANFAKECACSIPFYLSEAMRGNVYMYYKLYGFYQNLYRYILSRSNSQLVGTDIKDVTNCSPFKNSPNGTPIAPCGAIANSIFNDTIILSYNLNSSIHIKVPMLRSGITWWTDKYVKFQNPSSHNLSSAFAGTTKPPYWPKPAYELDEEDPGNNGFINDDFIVWMRTAAFPTFKKLYRRLHRVQHFTEGLPAGDQVYLHHDNPKVSEKRRLWGDSTGNQSDKHRRQEEQEKAILKCQTLESKLVNLAREARKSEGGDCQDREE", "length": 343, "header": "tr|A0A5G2R6H6-1|A0A5G2R6H6_PIG Isoform 1 of Cell cycle control protein 50C OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R6H6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R6H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6/entry#A0A5G2R6H6-1", "sequence": { "sequence": "MKRKSQDSQSRLPDNTAVKQQQLPAYRLQLSAKEILSGFFATGVFCLGIGIILLLSAKSIKEIEINYTEKCANCAKLRENAANFAKECACSIPFYLSEAMRGNVYMYYKLYGFYQNLYRYILSRSNSQLVGTDIKDVTNCSPFKNSPNGTPIAPCGAIANSIFNDTIILSYNLNSSIHIKVPMLRSGITWWTDKYVKFQNPSSHNLSSAFAGTTKPPYWPKPAYELDEEDPGNNGFINDDFIVWMRTAAFPTFKKLYRRLHRVQHFTEGLPAGDQVYLHHDNPKVSEKRRLWGDSTGNQSDKHRRQEEQEKAILKCQTLESKLVNLAREARKSEGGDCQDREE", "length": 343, "header": "tr|A0A5G2R6H6-1|A0A5G2R6H6_PIG Isoform 1 of Cell cycle control protein 50C OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R6H6-1" }, "locus": { "chromosome": "13", "start_pos": 158794250, "end_pos": 158747076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079215.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079215.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066200.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066200.1" } ] } }, { "isoform_ac": "F1SKZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6/entry#F1SKZ4-1", "sequence": { "sequence": "MKRKSQDSQSRLPDNTAVKQQQLPAYRLQLSAKEILSGFFATGVFCLGIGIILLLSAKSIKEIEINYTEKCANCAKLRENAANFAKECACSIPFYLSEAMRGNVYMYYKLYGFYQNLYRYILSRSNSQLVGTDIKDVTNCSPFKNSPNGTPIAPCGAIANSIFNDTIILSYNLNSSIHIKVPMLRSGITWWTDKYVKFQNPSSHNLSSAFAGTTKPPYWPKPAYELDEEDPGNNGFINDDFIVWMRTAAFPTFKKLYRRLHRVQHFTEGLPAGSYSFNITYNFPVSRFQGEKSVVLSTLTWSGGSSLFLGLAYVVTGAVTWLAFFSMMAIHLRLKERKGFFLQ", "length": 343, "header": "tr|F1SKZ4-1|A0A5G2R6H6_PIG Computationally mapped isoform of Cell cycle control protein 50C OS=Sus scrofa OX=9823 GN= PE=3 SV=3 CANONICAL=A0A5G2R6H6-1" }, "locus": { "chromosome": "13", "start_pos": 158794250, "end_pos": 158770514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013094.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013094.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012749.3", "url": "https://www.ensembl.org/id/ENSSSCP00000012749.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SKZ4", "url": "https://www.uniprot.org/uniprotkb/F1SKZ4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M9X1-1", "protein_name": "Cell cycle control protein", "gene_name": "LOC100755866", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEVMPQYDLSRLPENTALKQQKLPAHRLDLSASVVLSIFFATGGFCLCMGVILILSAKSTKELEINYTNICANCAQLREDSSNFDKECTCSVPFYLPENMEGNVYMYYKLYGFHQNLYRYILSRSNRQLLGKDIWDVKDCSPFQVSRNSTPIIPCGAIANSIFNDTITLSYNLNSSIHIEVPMLKSGLAWWTDKYVKFQNPRASDLASAFAGSAKPLHWTKPVYELDTDDPGNNGFVNEDLIVWMRTAAFPTFKKLYRRLKRVDYFAVGLPAGNYSFNISYNFPVTVFRGEKSVVLSTLTWIGGGGLFLGLTYTVTGALTLLASFAILAIHLMLKRTKKNFL", "length": 342 }, "evidence": [ { "id": "A0A5G2R6H6", "url": "https://omabrowser.org/oma/group/A0A5G2R6H6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XS32-1", "protein_name": "Cell cycle control protein", "gene_name": "TMEM30CP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKNKKSSAPQEAETRPSRCPDNSAFKQQKLPAWKPQLTAASVLSTFFLTGAFCLSVGVSLIVAAKSVREIQVDYSDKCSHCSKLRENSSNWNSECLCSINITLAEDMLGDVFMYYGLQNFYQNHRRYALSRSDEQLLGRNVDVQNSYCAPFATYQNGTPMAPCGAIANSMFNDTIDLFYNFNSSVIQVPLLKTGNSWWTDKNVKFRNPESHNLSAAFAGTARPPYWHKAVYLLDEEDEKNNGYINDDFIIWMRVSAFATFRNLYRRISRKGQFTDGLPAGNYTFHISYNFPVSKFKGKKYVILSTMVWSGGSNPFLGIAYLVCGAAATLTDALKLFPECRNNAEELRSRIA", "length": 351 }, "evidence": [ { "id": "A0A5G2R6H6", "url": "https://omabrowser.org/oma/group/A0A5G2R6H6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4AAH8-1", "protein_name": "Cell cycle control protein", "gene_name": "Tmem30c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEMVPQYDLSRLPENTALKQQTLPAQQLNLSASIVLSIFFATGGFCLSVGVILLLFAKSTKEIEINYTNMCANCAQLREDSSNFDKECNCSLPLYLPEKMEGDVYMYYKLYGFYQNLYRYILSRSNSQLVGKDIWDTTNCSPFQVSKNDTPIIPCGAIANSIFNDTITLSYNLNSSTQIEVPMLRSGLTWWTDKYVKFRNPRTSNFTSTFAGSSKPLHWAKPVYELDLEDPGNNGFVNEDFIVWMRTAAFPTFRKLYRRLRREDSFADGLPAGNYSLSISYNFPVTMFQGEKSVILSTLTWFGGGGLFLGLTYTVTGALTLLASFAILAVHLKLKRNKLSFL", "length": 342 }, "evidence": [ { "id": "A0A5G2R6H6", "url": "https://omabrowser.org/oma/group/A0A5G2R6H6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2T9P5-1", "protein_name": "Cell cycle control protein 50C", "gene_name": "TMEM30C", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKRKCQDYESRLPDNTAVKQQQLPAFRLQLTASEILSGFFAIGLFCLGMGIILLLSAKSIKEVEINYTEKCATCAKLREEATNFDKECNCSISFYLPQKMEGNVYLYYKLYGFYQNLYRYILSRSNIQLVGADVKDVRNCAPFRTSDNGLPIAPCGAIANSMFNDTIVLWYNFNSSTHIRVPMVRTETAWWTDKYVKFQNPAFQNLSSAFAGTAKPPNWPKPVYELDENDPGNNGFINDDFIVWMRTAAFPNFKKLYRRLHRIGNFTEGLPAGSYSFIINYNFPVSRFQGQKAVVLSTLTWSGGSSLFLALAYLVTGAVTLLASFSMMALHLKLKERKTFFLQ", "length": 343 }, "evidence": [ { "id": "A0A5G2R6H6", "url": "https://omabrowser.org/oma/group/A0A5G2R6H6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D4D7-1", "protein_name": "Cell cycle control protein 50C", "gene_name": "Tmem30c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMMPQYDLSRLPENTALKQQTLPTQQLNLSASVVLSIFFITGGFCLSIGIILLLSAKSTKKIEINYTKTCANCAQLRENSSNFDKACNCSLPFYLPEKMEGDVYMYYKLYGFYQNLYQYILSRSNSQLVGKDIWDTTNCDPFQVSHNDTPIIPCGAIANSIFNDTITLSYNLNSSTQIEVPMLKSGLTWWTDKYVKFRNPRSSNFTSTFAGSSKPLHWAKPIYELDLDDPGNNGFLNEDFIVWMRTAAFPTFKKLYRRLKRVHAFAEGLPAGNYSLSISYNFPVTMFQGEKSIVLSTLTWIGGGGLFLGLTYTVTGALTLLASFAILTIHLMLKRSKLNFL", "length": 342 }, "evidence": [ { "id": "A0A5G2R6H6", "url": "https://omabrowser.org/oma/group/A0A5G2R6H6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6H6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6H6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6H6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6H6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6H6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aminophospholipid flippase activity", "id": "GO:0015247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015247", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6H6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R6H6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 343, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R6H6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6H6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 148, "end_pos": 150 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R6J3-1", "uniprot_ac": "A0A5G2R6J3", "uniprot_id": "A0A5G2R6J3_PIG", "mass": { "chemical_mass": 35484.0, "monoisotopic_mass": 35484.0 }, "refseq": { "ac": "XP_003122194", "name": "olfactory receptor 1L8-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122194" }, "gene_names": [ { "name": "LOC100523835", "type": "recommended", "evidence": [ { "id": "A0A5G2R6J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3" } ] }, { "name": "LOC100523835", "type": "synonym", "evidence": [ { "id": "XP_003122194", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122194" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R6J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1L8-like", "type": "synonym", "evidence": [ { "id": "XP_003122194", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122194" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100523835", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3", "locus": {} } ], "crossref": [ { "id": "A0A5G2R6J3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6J3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15235", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15235", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523835", "url": "https://www.ncbi.nlm.nih.gov/gene/100523835", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523835", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523835", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMRIFIT", "url": "https://omabrowser.org/oma/group/YMRIFIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R6J3", "url": "https://www.orthodb.org/?gene=A0A5G2R6J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003122194", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122194", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R6J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERVNQTSSVSEFILLGLSSRPEDQKPLFTLFLTIYLVTITGNLLIILAIRSDPQLQTPMYFFLTFLSFTDICFTTTIVPRMLVNFLSHKTISYAGCLTQMYFLYALGNTDSFLLAVMAFDRYVAICDPFHYVTIMSHHRCALMVALSCSLPHLHSLLHTLLLNQLTFCDSNIIHHFLCDLSPLMKLSCSSTFVNETVMMIEGPILLVTPFLCITFSYIRILTVVLKIPSAAGKRKAFSTCGSHVTVVTLFYGSIFYVYLQPVSSYTVRDHMATIVYTVLSSMLNPFIYSLRNKDLKQGLRKLVGSRKFKAACS", "length": 314, "header": "tr|A0A5G2R6J3-1|A0A5G2R6J3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100523835 PE=3 SV=1 CANONICAL=A0A5G2R6J3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R6J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3/entry#A0A5G2R6J3-1", "sequence": { "sequence": "MERVNQTSSVSEFILLGLSSRPEDQKPLFTLFLTIYLVTITGNLLIILAIRSDPQLQTPMYFFLTFLSFTDICFTTTIVPRMLVNFLSHKTISYAGCLTQMYFLYALGNTDSFLLAVMAFDRYVAICDPFHYVTIMSHHRCALMVALSCSLPHLHSLLHTLLLNQLTFCDSNIIHHFLCDLSPLMKLSCSSTFVNETVMMIEGPILLVTPFLCITFSYIRILTVVLKIPSAAGKRKAFSTCGSHVTVVTLFYGSIFYVYLQPVSSYTVRDHMATIVYTVLSSMLNPFIYSLRNKDLKQGLRKLVGSRKFKAACS", "length": 314, "header": "tr|A0A5G2R6J3-1|A0A5G2R6J3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100523835 PE=3 SV=1 CANONICAL=A0A5G2R6J3-1" }, "locus": { "chromosome": "AEMK02000620.1", "start_pos": 82245, "end_pos": 81304, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081080.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081080.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069747.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069747.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523835", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523835", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6J3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R6J3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R6J3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6J3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R6J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6J3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R6L0-1", "uniprot_ac": "A0A5G2R6L0", "uniprot_id": "A0A5G2R6L0_PIG", "mass": { "chemical_mass": 12754.0, "monoisotopic_mass": 12754.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit TMEM258", "type": "recommended", "evidence": [ { "id": "A0A5G2R6L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein 258", "type": "synonym", "evidence": [ { "id": "A0A5G2R6L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6L0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0#function" }, { "database": "UniProtKB", "id": "RU367008", "url": "https://www.uniprot.org/uniprotkb/RU367008#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6L0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0", "locus": {} } ], "crossref": [ { "id": "A0A5G2R6L0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6L0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000046245", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000046245", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13636", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13636", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05251", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05251", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R6L0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LDALIPKYHSLIAFISQLTNDILSIPISLKKQQLNSGAVDHTVPCKMDEPGFLSPSDHVLLVIGMLFTAEFFVYEVTSTKHPRDISKKLLIILVASHFKGFGVLFLLLWVSIYV", "length": 114, "header": "tr|A0A5G2R6L0-1|A0A5G2R6L0_PIG Isoform 1 of Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit TMEM258 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R6L0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R6L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0/entry#A0A5G2R6L0-1", "sequence": { "sequence": "LDALIPKYHSLIAFISQLTNDILSIPISLKKQQLNSGAVDHTVPCKMDEPGFLSPSDHVLLVIGMLFTAEFFVYEVTSTKHPRDISKKLLIILVASHFKGFGVLFLLLWVSIYV", "length": 114, "header": "tr|A0A5G2R6L0-1|A0A5G2R6L0_PIG Isoform 1 of Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit TMEM258 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R6L0-1" }, "locus": { "chromosome": "2", "start_pos": 99014975, "end_pos": 99013669, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085130.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085130.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071975.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071975.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6L0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6L0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0" } ], "pmid": "" }, { "name": "oligosaccharyltransferase complex", "id": "GO:0008250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008250", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6L0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6L0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6L0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oligosaccharyltransferase complex binding", "id": "GO:0062062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062062", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6L0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6L0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R6L0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 114, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R6L0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6L0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R6N4-1", "uniprot_ac": "A0A5G2R6N4", "uniprot_id": "A0A5G2R6N4_PIG", "mass": { "chemical_mass": 62996.0, "monoisotopic_mass": 62996.0 }, "refseq": {}, "gene_names": [ { "name": "RANGAP1", "type": "recommended", "evidence": [ { "id": "A0A5G2R6N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ] } ], "protein_names": [ { "name": "Ran GTPase-activating protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2R6N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RANGAP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4", "locus": { "chromosome": "5", "start_pos": 7241003, "end_pos": 7211010, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000028202", "url": "https://www.ensembl.org/id/ENSSSCG00000028202" } ] } } ], "crossref": [ { "id": "A0A5G2R6N4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6N4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000028202", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000028202", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24113:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24113:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07834", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07834", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68877", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9615933", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9615933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9793242", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9793242", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8N6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LT48", "url": "https://www.uniprot.org/uniprotkb/I3LT48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LT48-1", "url": "https://www.uniprot.org/uniprotkb/I3LT48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDGLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLRSSTCFTLHELKLNNCGMGAGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGVTALAQAFAINPLLRINLNDNTFTEKGAVAMAKTLKTLRQVEAINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALSVAEAVADKAKLEKLDLNGNTLGEEGCEQLQEVLDGFNMAKVLASLSDDEGEDDEDEEEEGEEEEEEEEEEEEEEEEEEEEEEEEPQQGEQGEEPATPPRKILDPTSGEPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVFKDEAAVRTAVQDAVDALMKKAFGSSAFNSNAFLTRLLIHMGLLKSEDKIKAIANLYGPLMALNHMVQQDYFPKALAPLLLAFMTKPNGALESCSFARHNLLQTLYKV", "length": 585, "header": "tr|A0A5G2R6N4-1|A0A5G2R6N4_PIG Isoform 1 of Ran GTPase-activating protein 1 OS=Sus scrofa OX=9823 GN=RANGAP1 PE=1 SV=1 CANONICAL=A0A5G2R6N4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R6N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4/entry#A0A5G2R6N4-1", "sequence": { "sequence": "MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDGLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLRSSTCFTLHELKLNNCGMGAGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGVTALAQAFAINPLLRINLNDNTFTEKGAVAMAKTLKTLRQVEAINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALSVAEAVADKAKLEKLDLNGNTLGEEGCEQLQEVLDGFNMAKVLASLSDDEGEDDEDEEEEGEEEEEEEEEEEEEEEEEEEEEEEEPQQGEQGEEPATPPRKILDPTSGEPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVFKDEAAVRTAVQDAVDALMKKAFGSSAFNSNAFLTRLLIHMGLLKSEDKIKAIANLYGPLMALNHMVQQDYFPKALAPLLLAFMTKPNGALESCSFARHNLLQTLYKV", "length": 585, "header": "tr|A0A5G2R6N4-1|A0A5G2R6N4_PIG Isoform 1 of Ran GTPase-activating protein 1 OS=Sus scrofa OX=9823 GN=RANGAP1 PE=1 SV=1 CANONICAL=A0A5G2R6N4-1" }, "locus": { "chromosome": "5", "start_pos": 7240024, "end_pos": 7213772, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089861.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089861.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069787.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069787.1" } ] } }, { "isoform_ac": "A0A5G2R8N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4/entry#A0A5G2R8N6-1", "sequence": { "sequence": "MGLTLTLRQVEAINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALSVAEAVADKAKLEKLDLNGNTLGEEGCEQLQEVLDGFNMAKVLASLSDDEGEDDEDEEEEGEEEEEEEEEEEEEEEEEEEEEEEEPQQGEQGEEPATPPRKILDPTSGEPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVFKDEAAVRTAVQDAVDALMKKAFGSSAFNSNAFLTRLLIHMGLLKSEDKIKAIANLYGPLMALNHMVQQDYFPKALAPLLLAFMTKPNGALESCSFARHNLLQTLYKV", "length": 330, "header": "tr|A0A5G2R8N6-1|A0A5G2R6N4_PIG Computationally mapped isoform of Ran GTPase-activating protein 1 OS=Sus scrofa OX=9823 GN=RANGAP1 PE=1 SV=1 CANONICAL=A0A5G2R6N4-1" }, "locus": { "chromosome": "5", "start_pos": 7240024, "end_pos": 7230386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081533.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081533.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066973.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066973.1" } ] } }, { "isoform_ac": "I3LT48-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4/entry#I3LT48-1", "sequence": { "sequence": "MAKTLKTLRQVEAINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALSVAEAVADKAKLEKLDLNGNTLGEEGCEQLQEVLDGFNMAKVLASLSDDEGEDDEDEEEEEEEEEEEEPQQGEQGEEPATPPRKILDPTSGEPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVFKDEAAVRTAVQDAVDALMKKAFGSSAFNSNAFLTRLLIHMGLLKSEDKIKAIANLYGPLMALNHMVQQDYFPKALAPLLLAFMTKPNGALESCSFARHNLLQTLYKV", "length": 314, "header": "tr|I3LT48-1|A0A5G2R6N4_PIG Computationally mapped isoform of Ran GTPase-activating protein 1 OS=Sus scrofa OX=9823 GN=RANGAP1 PE=1 SV=3 CANONICAL=A0A5G2R6N4-1" }, "locus": { "chromosome": "5", "start_pos": 7240024, "end_pos": 7229438, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031198.4", "url": "https://www.ensembl.org/id/ENSSSCT00000031198.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027292.3", "url": "https://www.ensembl.org/id/ENSSSCP00000027292.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LT48", "url": "https://www.uniprot.org/uniprotkb/I3LT48" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-SSC-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-SSC-4615885", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4615885", "resource": "Reactome", "description": "SUMOylation of DNA replication proteins" }, { "id": "R-SSC-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-SSC-68877", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "resource": "Reactome", "description": "Mitotic Prometaphase" }, { "id": "R-SSC-9615933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9615933", "resource": "Reactome", "description": "Postmitotic nuclear pore complex (NPC) reformation" }, { "id": "R-SSC-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" }, { "id": "R-SSC-9793242", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9793242", "resource": "Reactome", "description": "SUMOylation of nuclear envelope proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "pmid": "" }, { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "pmid": "" }, { "name": "nuclear export", "id": "GO:0051168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051168", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "pmid": "" }, { "name": "negative regulation of protein export from nucleus", "id": "GO:0046826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046826", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R6N4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 585, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R6N4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6N4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R6N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6N4" }, { "id": "PF07834", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07834" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ran-GTPase activating protein 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 409, "end_pos": 582, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R6S9-1", "uniprot_ac": "A0A5G2R6S9", "uniprot_id": "A0A5G2R6S9_PIG", "mass": { "chemical_mass": 35803.0, "monoisotopic_mass": 35803.0 }, "refseq": { "ac": "NP_001422537", "name": "BAG family molecular chaperone regulator 1 isoform 1L", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422537" }, "gene_names": [ { "name": "BAG1", "type": "recommended", "evidence": [ { "id": "A0A5G2R6S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ] }, { "name": "BAG1", "type": "synonym", "evidence": [ { "id": "NP_001422537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422537" } ] } ], "protein_names": [ { "name": "BAG family molecular chaperone regulator 1", "type": "recommended", "evidence": [ { "id": "A0A5G2R6S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9/entry#names_and_taxonomy" } ] }, { "name": "BAG family molecular chaperone regulator 1 isoform 1L", "type": "synonym", "evidence": [ { "id": "NP_001422537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422537" } ] }, { "name": "BCL2 associated athanogene 1", "type": "synonym", "evidence": [ { "id": "NP_001422537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422537" } ] }, { "name": "hydroxysteroid (17-beta) dehydrogenase 3", "type": "synonym", "evidence": [ { "id": "NP_001422537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422537" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BAG1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9", "locus": { "chromosome": "10", "start_pos": 33242230, "end_pos": 33227337, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010996", "url": "https://www.ensembl.org/id/ENSSSCG00000010996" } ] } } ], "crossref": [ { "id": "A0A5G2R6S9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6S9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010996", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010996", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01812", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01812", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513225", "url": "https://www.ncbi.nlm.nih.gov/gene/100513225", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513225", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513225", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HSECNEK", "url": "https://omabrowser.org/oma/group/HSECNEK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QPH3", "url": "https://www.orthodb.org/?gene=A0A5G2QPH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12329:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12329:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3371453", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001422537", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422537", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QPH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UNP6", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UNP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UNP6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UNP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UPW5", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UPW5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SE85", "url": "https://www.uniprot.org/uniprotkb/F1SE85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SE85-1", "url": "https://www.uniprot.org/uniprotkb/F1SE85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAESGGARRPRGDRERLGPRRRAPRPGREPRQSVPPAERGSPPSERSAVRSVTRGHAGSTRGAAACSRRPRMKKKARPRSAGSEEVTRNEEVSRSEEVVRSEEAALSEEVARSEEMAAAGLSVTVTHSNEKHDLQVIPQEGCSEPIVQDLAQVVEEATGVPLPFQKLIFKGKSLKEMKTPLSALGIQNGCRIMLIGKKNSSEEEVELKKLKDLERSVEKIAHQLEELNKELTGIQQGFLAKDLQAEALCKLDRRIKATIEQFMKILEEIDTLILPENFKDSRMKRKGLVKRIQGFLAECDTVEQNICLETERLQSTNLALAD", "length": 322, "header": "tr|A0A5G2R6S9-1|A0A5G2R6S9_PIG Isoform 1 of BAG family molecular chaperone regulator 1 OS=Sus scrofa OX=9823 GN=BAG1 PE=1 SV=2 CANONICAL=A0A5G2R6S9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QPH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9/entry#A0A5G2QPH3-1", "sequence": { "sequence": "MKKKARPRSAGSEEVTRNEEVSRSEEVVRSEEAALSEEVARSEEMAAAGLSVTVTHSNEKHDLQVIPQEGCSEPIVQDLAQVVEEATGVPLPFQKLIFKGKSLKEMKTPLSALGIQNGCRIMLIGKKNSSEEEVELKKLKDLERSVEKIAHQLEELNKELTGIQQGFLAKDLQAEALCKLDRRIKATIEQFMKILEEIDTLGFLAECDTVEQNICLETERLQSTNLALAD", "length": 230, "header": "tr|A0A5G2QPH3-1|A0A5G2QPH3_PIG Computationally mapped isoform of BAG family molecular chaperone regulator 1 OS=Sus scrofa OX=9823 GN=BAG1 PE=1 SV=1 CANONICAL=A0A5G2R6S9-1" }, "locus": { "chromosome": "10", "start_pos": 33239811, "end_pos": 33227858, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066892.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066892.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060187.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060187.1" } ] } }, { "isoform_ac": "A0A5G2R6S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9/entry#A0A5G2R6S9-1", "sequence": { "sequence": "MAESGGARRPRGDRERLGPRRRAPRPGREPRQSVPPAERGSPPSERSAVRSVTRGHAGSTRGAAACSRRPRMKKKARPRSAGSEEVTRNEEVSRSEEVVRSEEAALSEEVARSEEMAAAGLSVTVTHSNEKHDLQVIPQEGCSEPIVQDLAQVVEEATGVPLPFQKLIFKGKSLKEMKTPLSALGIQNGCRIMLIGKKNSSEEEVELKKLKDLERSVEKIAHQLEELNKELTGIQQGFLAKDLQAEALCKLDRRIKATIEQFMKILEEIDTLILPENFKDSRMKRKGLVKRIQGFLAECDTVEQNICLETERLQSTNLALAD", "length": 322, "header": "tr|A0A5G2R6S9-1|A0A5G2R6S9_PIG Isoform 1 of BAG family molecular chaperone regulator 1 OS=Sus scrofa OX=9823 GN=BAG1 PE=1 SV=2 CANONICAL=A0A5G2R6S9-1" }, "locus": { "chromosome": "10", "start_pos": 33239811, "end_pos": 33227645, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077020.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077020.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072040.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072040.2" } ] } }, { "isoform_ac": "A0ABB5UNP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9/entry#A0ABB5UNP6-1", "sequence": { "sequence": "MKKKARPRSAGSEEVTRNEEVSRSEEVVRSEEAALSEEVARSEEMAAAGLSVTVTHSNEKHDLQVIPQEGCSEPIVQDLAQVVEEATGVPLPFQKLIFKGKSLKEMKTPLSALGIQNGCRIMLIGKKNSSEEEVELKKLKDLERSVEKIAHQLEELNKELTGIQQGFLAKDLQAEALCKLDRRIKATIEQFMKILEEIDTLILPENFKDSRMKRKGLVKRIQVSCVVEHQSITCGA", "length": 236, "header": "tr|A0ABB5UNP6-1|A0ABB5UNP6_PIG Computationally mapped isoform of BAG family molecular chaperone regulator 1 OS=Sus scrofa OX=9823 GN=BAG1 PE=1 SV=1 CANONICAL=A0A5G2R6S9-1" }, "locus": { "chromosome": "10", "start_pos": 33238853, "end_pos": 33227858, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107043.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107043.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081445.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081445.1" } ] } }, { "isoform_ac": "A0ABB5UPW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9/entry#A0ABB5UPW5-1", "sequence": { "sequence": "MKKKARPRSAGSEEVTRNEEVSRSEEVVRSEEAALSEEVARSEEMAAAGLSVTVTHRKSLKEMKTPLSALGIQNGCRIMLIGKKNSSEEEVELKKLKDLERSVEKIAHQLEELNKELTGIQQGFLAKDLQAEALCKLDRRIKATIEQFMKILEEIDTLILPENFKDSRMKRKGLVKRIQGFLAECDTVEQNICLETERLQSTNLALAD", "length": 208, "header": "tr|A0ABB5UPW5-1|A0ABB5UPW5_PIG Computationally mapped isoform of BAG cochaperone 1 OS=Sus scrofa OX=9823 GN=BAG1 PE=1 SV=1 CANONICAL=A0A5G2R6S9-1" }, "locus": { "chromosome": "10", "start_pos": 33239811, "end_pos": 33227858, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107044.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107044.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081446.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081446.1" } ] } }, { "isoform_ac": "F1SE85-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9/entry#F1SE85-1", "sequence": { "sequence": "MKKKARPRSAGSEEVTRNEEVSRSEEVVRSEEAALSEEVARSEEMAAAGLSVTVTHSNEKHDLQVIPQEGCSEPIVQDLAQVVEEATGVPLPFQKLIFKGKSLKEMKTPLSALGIQNGCRIMLIGKKNSSEEEVELKKLKDLERSVEKIAHQLEELNKELTGIQQGFLAKDLQAEALCKLDRRIKATIEQFMKILEEIDTLILPENFKDSRMKRKGLVKRIQGFLAECDTVEQNICLETERLQSTNLALAD", "length": 251, "header": "tr|F1SE85-1|F1SE85_PIG Computationally mapped isoform of BAG family molecular chaperone regulator 1 OS=Sus scrofa OX=9823 GN=BAG1 PE=1 SV=2 CANONICAL=A0A5G2R6S9-1" }, "locus": { "chromosome": "10", "start_pos": 33239811, "end_pos": 33227858, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012037.6", "url": "https://www.ensembl.org/id/ENSSSCT00000012037.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011729.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011729.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Thr", "end_pos": 53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513225", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513225", "resource": "KEGG Pathway" }, { "id": "R-SSC-3371453", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "resource": "Reactome", "description": "Regulation of HSF1-mediated heat shock response" } ], "orthologs": [ { "uniprot_canonical_ac": "B0K019-1", "protein_name": "BAG family molecular chaperone regulator 1", "gene_name": "Bag1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADRGGARRPRGDQEPLGPRLRAPRSARETRQSESRAERGLPPSQRSSVRSAASGHDRSTRGAASGACKPRVKKKVRPRSSQSEKVAHSKELTRSKKLTRSKKVTGTQEATQVEEVTTIEEATQTEEITVAEEVTQTENMAQTEEMVQTEEMEPPTLSVVVTHSNERYDLLVTPQQGNSEPIVQDLAQLVEEATGVPLPFQKLIFKGKSLKEMETPLSALGMQNGCRVMLIGEKSNPEEEAELKKLKDLEVSVEKTANHLEELNKELSDIQQGFLAKELQAEALCRLDRKIKATIEQFMKILEEIDTMVLPENFKDSRLKRKNLVKKVQVFLAECDTVEQYICQETERLQSTNLALPE", "length": 358 }, "evidence": [ { "id": "A0A5G2R6S9", "url": "https://omabrowser.org/oma/group/A0A5G2R6S9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NPL0-1", "protein_name": "BCL2 associated athano 1", "gene_name": "BAG1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVPGAPVSVTVTYSNEKHNIQVASQQEDGEPTLQDMAVLIEQVTGVPVSFQKLIYKGKSLKELEQPLSALGVKNGCKVMLIGKRNSPEEEAELKKLKDLEKSVEQIANKLEEVNKEFTSIQKGFLAKDLQAEALKQLDKRIKGTAEQFMKILEQVDAINLPENFNDCRLKKKGLVKRVQAFLAQCDTVEGNIGQEMDKLQSKNLALAE", "length": 209 }, "evidence": [ { "id": "A0A5G2R6S9", "url": "https://omabrowser.org/oma/group/A0A5G2R6S9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q60739-1", "protein_name": "BAG family molecular chaperone regulator 1", "gene_name": "Bag1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGRSAARRPRGDREPLGPRLRAPRPAREPRQSESRAERGLPPSQRSSVRSAASGHDRSTRGAPAGACKPRVKKKVRPRSSQSEKVGSSSRELTRSKKVTRSKNVTGTQVEEVTKIEEATQTEEVTVAEEVTQTDNMAKTEEMVQTEEMETPRLSVIVTHSNERYDLLVTPQQGNSEPVVQDLAQLVEEATGVPLPFQKLIFKGKSLKEMETPLSALGMQNGCRVMLIGEKSNPEEEVELKKLKDLEVSAEKIANHLQELNKELSGIQQGFLAKELQAEALCKLDRKVKATIEQFMKILEEIDTMVLPEQFKDSRLKRKNLVKKVQVFLAECDTVEQYICQETERLQSTNLALAE", "length": 355 }, "evidence": [ { "id": "A0A5G2R6S9", "url": "https://omabrowser.org/oma/group/A0A5G2R6S9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99933-1", "protein_name": "BAG family molecular chaperone regulator 1", "gene_name": "BAG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQRGGARRPRGDRERLGSRLRALRPGREPRQSEPPAQRGPPPSGRPPARSTASGHDRPTRGAAAGARRPRMKKKTRRRSTRSEELTRSEELTLSEEATWSEEATQSEEATQGEEMNRSQEVTRDEESTRSEEVTREEMAAAGLTVTVTHSNEKHDLHVTSQQGSSEPVVQDLAQVVEEVIGVPQSFQKLIFKGKSLKEMETPLSALGIQDGCRVMLIGKKNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQETERLQSTNFALAE", "length": 345 }, "evidence": [ { "id": "A0A5G2R6S9", "url": "https://omabrowser.org/oma/group/A0A5G2R6S9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ], "pmid": "" }, { "name": "adenyl-nucleotide exchange factor activity", "id": "GO:0000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000774", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6S9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R6S9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 322, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R6S9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6S9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R6S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" }, { "id": "PS51035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAG", "eco_id": "ECO_0000259", "start_pos": 223, "end_pos": 303, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R6S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6S9" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 121, "end_pos": 201, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 53 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R6Y6-1", "uniprot_ac": "A0A5G2R6Y6", "uniprot_id": "A0A5G2R6Y6_PIG", "mass": { "chemical_mass": 34558.0, "monoisotopic_mass": 34558.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R6Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6", "locus": {} } ], "crossref": [ { "id": "A0A5G2R6Y6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6Y6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15227", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15227", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R6Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKKSTNTTIVTEFLLMRFPDDQVLQGLYVTFFLLIYLAALMGNFLIITLTTTDKCLQSPMYFFLKNLSLIDICFISVTVPKAIINALTKSQTISFLGCASQIFLFIFLAGTEYALLIAMSYDRYVAICHPLYYEAIVNRGTCWQMVTASWSSGCIYGSVHVGGTFSAHFCGPNIVHQFFCDIPSVLTLACSGENLEYAFIIASCIFAFVCFLFLIASYIYIFSAVLRIPSAKGRLKSFSTCMPHLIVVMLFLFSGIVTYLGSNYKSASSLNLLISVLYSMLPPSLNPLIYSLRNKDMKEALGKMVKYW", "length": 309, "header": "tr|A0A5G2R6Y6-1|A0A5G2R6Y6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R6Y6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R6Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6/entry#A0A5G2R6Y6-1", "sequence": { "sequence": "MAKKSTNTTIVTEFLLMRFPDDQVLQGLYVTFFLLIYLAALMGNFLIITLTTTDKCLQSPMYFFLKNLSLIDICFISVTVPKAIINALTKSQTISFLGCASQIFLFIFLAGTEYALLIAMSYDRYVAICHPLYYEAIVNRGTCWQMVTASWSSGCIYGSVHVGGTFSAHFCGPNIVHQFFCDIPSVLTLACSGENLEYAFIIASCIFAFVCFLFLIASYIYIFSAVLRIPSAKGRLKSFSTCMPHLIVVMLFLFSGIVTYLGSNYKSASSLNLLISVLYSMLPPSLNPLIYSLRNKDMKEALGKMVKYW", "length": 309, "header": "tr|A0A5G2R6Y6-1|A0A5G2R6Y6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R6Y6-1" }, "locus": { "chromosome": "2", "start_pos": 56290151, "end_pos": 56289225, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095222.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095222.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078077.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078077.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R6Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R6Y6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R6Y6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R6Y6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R6Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6Y6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 67, "end_pos": 69 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R717-1", "uniprot_ac": "A0A5G2R717", "uniprot_id": "A0A5G2R717_PIG", "mass": { "chemical_mass": 71043.0, "monoisotopic_mass": 71043.0 }, "refseq": {}, "gene_names": [ { "name": "HSPA6", "type": "recommended", "evidence": [ { "id": "A0A5G2R717", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ] } ], "protein_names": [ { "name": "Heat shock 70 kDa protein 6", "type": "recommended", "evidence": [ { "id": "A0A5G2R717", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HSPA6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717", "locus": { "chromosome": "4", "start_pos": 88970599, "end_pos": 88973918, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000047932", "url": "https://www.ensembl.org/id/ENSSSCG00000047932" } ] } } ], "crossref": [ { "id": "A0A5G2R717", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R717", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000047932", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000047932", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10233", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10233", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR013126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19375", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19375", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3371453", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R717-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAAREVAIGIDLGTTYSCVGVFQHGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPQNTVFDAKRLIGRKFADPTVQSDLKHWPFQVVSEGGKPKVRVSYRGEDKAFYPEEISSMVLSKMKETAEAYLGQPVRHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLTIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEFRRKHRKDLSTNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILSVTATDRSTGRANKITITNDKGRLSKEEVERMVREAEQYKVEDEAQRDRVAAKNSLEAYVFHVKGSLHEESLRDKIPEEDRCKVQDKCQEVLTWLEHNQLAEKEEYEHQKRELEQICRPIFSRLYGGSGIPGGSSCGAQARQGAPSTGPVIEEVD", "length": 643, "header": "tr|A0A5G2R717-1|A0A5G2R717_PIG Isoform 1 of Heat shock 70 kDa protein 6 OS=Sus scrofa OX=9823 GN=HSPA6 PE=3 SV=1 CANONICAL=A0A5G2R717-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R717-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717/entry#A0A5G2R717-1", "sequence": { "sequence": "MSAAREVAIGIDLGTTYSCVGVFQHGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPQNTVFDAKRLIGRKFADPTVQSDLKHWPFQVVSEGGKPKVRVSYRGEDKAFYPEEISSMVLSKMKETAEAYLGQPVRHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLTIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEFRRKHRKDLSTNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILSVTATDRSTGRANKITITNDKGRLSKEEVERMVREAEQYKVEDEAQRDRVAAKNSLEAYVFHVKGSLHEESLRDKIPEEDRCKVQDKCQEVLTWLEHNQLAEKEEYEHQKRELEQICRPIFSRLYGGSGIPGGSSCGAQARQGAPSTGPVIEEVD", "length": 643, "header": "tr|A0A5G2R717-1|A0A5G2R717_PIG Isoform 1 of Heat shock 70 kDa protein 6 OS=Sus scrofa OX=9823 GN=HSPA6 PE=3 SV=1 CANONICAL=A0A5G2R717-1" }, "locus": { "chromosome": "4", "start_pos": 88973004, "end_pos": 88971076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085942.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085942.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073047.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073047.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3371453", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "resource": "Reactome", "description": "Regulation of HSF1-mediated heat shock response" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" }, { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" }, { "name": "COP9 signalosome", "id": "GO:0008180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008180", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" }, { "name": "protein refolding", "id": "GO:0042026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042026", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R717", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R717" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R717-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 643, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R717-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R717" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 419, "end_pos": 421 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R729-1", "uniprot_ac": "A0A5G2R729", "uniprot_id": "A0A5G2R729_PIG", "mass": { "chemical_mass": 24930.0, "monoisotopic_mass": 24930.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R729/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R729", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R729#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R729", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R729" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R729", "locus": {} } ], "crossref": [ { "id": "A0A5G2R729", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R729", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R729", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R729", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R729-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R729-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNECLTQVFALHLFGCMEIFVLVLMAMDRYVAICKPLHYATIMSRQACVILIVPAWIGSFLHSMAQIILALRLPFCGSNLINHYCCDMQPLLKLACMNIYVMNLLVVFNSGVICTISFTILMISYIAILHSLRNHSAEGRKKALSTCTSHIIVVVLFFGPCIFMYTRPPTTFPMDKMVAVFYTIGTPFLNPLIYTLRNAEVKNAMRKLWCVRITSENRR", "length": 219, "header": "tr|A0A5G2R729-1|A0A5G2R729_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R729-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R729-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R729/entry#A0A5G2R729-1", "sequence": { "sequence": "MNECLTQVFALHLFGCMEIFVLVLMAMDRYVAICKPLHYATIMSRQACVILIVPAWIGSFLHSMAQIILALRLPFCGSNLINHYCCDMQPLLKLACMNIYVMNLLVVFNSGVICTISFTILMISYIAILHSLRNHSAEGRKKALSTCTSHIIVVVLFFGPCIFMYTRPPTTFPMDKMVAVFYTIGTPFLNPLIYTLRNAEVKNAMRKLWCVRITSENRR", "length": 219, "header": "tr|A0A5G2R729-1|A0A5G2R729_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R729-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 118067, "end_pos": 117411, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099398.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099398.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080550.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080550.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R729", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R729" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R729", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R729" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R729", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R729" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R729", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R729" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R729-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 219, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R729-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R729" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R729" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 194, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R732-1", "uniprot_ac": "A0A5G2R732", "uniprot_id": "A0A5G2R732_PIG", "mass": { "chemical_mass": 357456.0, "monoisotopic_mass": 357456.0 }, "refseq": {}, "gene_names": [ { "name": "CELSR3", "type": "recommended", "evidence": [ { "id": "A0A5G2R732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" } ] } ], "protein_names": [ { "name": "Cadherin EGF LAG seven-pass G-type receptor 3", "type": "recommended", "evidence": [ { "id": "A0A5G2R732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732/entry#names_and_taxonomy" } ] }, { "name": "Multiple epidermal growth factor-like domains protein 2", "type": "synonym", "evidence": [ { "id": "A0A5G2R732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Receptor that may have an important role in cell/cell signaling during nervous system formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R732", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732#function" }, { "database": "UniProtKB", "id": "ARBA00002066", "url": "https://www.uniprot.org/uniprotkb/ARBA00002066#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R732", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CELSR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732", "locus": { "chromosome": "13", "start_pos": 31331574, "end_pos": 31357469, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011360", "url": "https://www.ensembl.org/id/ENSSSCG00000011360" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011360", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011360", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24026:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24026:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23592", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23592", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R732", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R732-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARRQPWWGLWGPMTPLLLFLLLLSLFPLSREELGGDGGQDWGPGVAAATGPGARIGGGALALCPEPPGVREDGKPGLGVKEPVFVGLQGGRQSTQNGRGPPEEPRLVAEFGVQAVGSRGRETGQGPGSLLCWRPEVSSCRRTGPLQRDSLSPEALSPGVPGPENSSPFPSDFLVRTRGSQPVFSQRNTGRGALKKVGTTRCCGELWAPGRRGQSERTATSRPDRPPGAVGSSPVLDSAPRTGRTALASGSAPRVSRTAPEPMPERMRSRGLFRRRFLPQRPGPRPPGVPAGPGAWRIPSAGRVRPRRAANHHPQFPQYNYQALVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQSGLIRTEAALDRESMDRHYLRVTAQDHGSPRLSATTMVAVTVTDRNDHAPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHTPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDATVGTSVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRALHDHCYVHINITDANTHRPVFQSAHYSVKVNEDQPVGSTVVVISASDDDVGENARITYLLEDNLPQFRIDADSGAITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHVNGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRWLDREAVPVYELTAYAVDRGVPPLRTPVSIQVTVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQEYVIVVQATSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPDVSDHLFYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVIITEELLANSLTVRLENMWQERFLSPLLGHFLEGVAAVLATPAEDVFIFNIQNDTDVGGTVLNVSFSALAPRGAGAGSAGPWFSSEELQEQLYVRRAALAARSLLDVLPFDDNVCLREPCENYMKCVSVLRFDSSAPFLASASTLFRPIQPIAGLRCRCPPGFTGDFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCADGPDGGFRCQCPAGGAFEGPRCEVAARSFPPSSFVMFRGLRQRFHLTLSLSFATVQPSGLLFYNGRLNEKHDFLALELVAGQVRLTYSTGESNTVVSPTVPGGLSDGQWHTVHLRYYNKPRTDALGGAQGPSKDKVAVLSVDDCDVAVALQFGAEIGNYSCAAAGTQTSSKKSLDLTGPLLLGGVPNLPENFPVSHKDFVGCMRDLHIDGRQVDMAGFVANNGTMAGCQAKLHFCDSGPCKNSGFCSERWGGFSCDCPVGFGGKDCRLTMAHPHHFRGNGTLSWDFGNDMAVSVPWYLGLAFRTRATQGVLMQVQAGPHSTLLCQLDRGLLSVTVTKGSGRAAHLLLDEVTVSDGRWHDLRLELQEEPGGRRGHHVLMVSLDFSLFQDTLAVGSELQGLKVKRLHVGGLPPGSEEEAPQGLVGCIQGVWLGSTPLGSPALLPPSHRVNVEPGCVVTNACASGPCPPHADCRDLWQTFSCTCWPGYYGPGCVDACLLNPCQNQGSCRHLPGAPLGYTCDCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDLCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCQVLYDACPKSLRSGVWWPQTKFGVLASVPCPRGALGAAVRLCDEDQGWLEPDLFNCTSPAFRELNLLLDGLELNKTVLDTVEAKKLAQRLREVTGHTDHYFSQDVRVTARLLAHLLAFESHQQGFGLTATQDAHFNENLLWAGSALLAPETGDLWAALGQRSPGGSPGSAGLVQHLEEYAATLARNMELTYLNPVGLVTPNIMLSIDRMEHPSPTRGTRRYPRYHSNLFRGQDAWDPHTHVLLPSQAPRPSSPEVLSTSSSTENSTTSSLAPPPVPLDPEPEPGISIVILLVYRTLGGLLPAQFQAERRGARLPQNPVMNSPVVSVAVFHGRNFLRGVLESPISLEFRLLQTANRSKAICVQWDPPGPADQHGMWTARDCELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVMAVSVAALLLTAAILLSLRSLKSNIRGIHANVAAALGVAELLFLLGIHRTQNQLVCTVVAILLHYFFLSTFAWLLVQGLHLYRMQVEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEGYGNPDFCWISVHEPLIWSFAGPVVLVIMMNGTLFLLAARTSCSTGQREAKKTSVLTLRSSFLLLLLVSASWLFGLLAVNHSILAFHYLHAGLCGLQGLVVLLLFCVLNADARAAWTPACLGRKAVPEEARPAPGTGPGAYNNTALFEESGLIRITLGASTISSVSSARSGRTQDQDSQRGRSYLRDNVLVRHGSAADHTDHSLQAHAGPTDLDVAMFHRDAGADSDSDSDLSLEEERSLSIPSSESEDNGRAQGRFQRPLHRAAQSERLLTHPKDMDGNDLLSYWPALGECEAAPCALQTWGSERRLGLDTSKDAANNNQPDLALTSGDETSLGRAQRQRKGILKNRLQYPLVPQTRGTPELSWCRAATLGHRAVPAASYGRIYAGGGTGSLSQPASRYSSREQLDLLLRRQLSREQLEEAPAPVLRPLSRPGSQEHLDAMPGRLEPRDRGSTLPRRQPPRDYPGTMAACFGSRDALDQGAPCEWLSTLPPPHGVQDLDPQPPPLPLSPQRQLSRDPLLPSRPLDSLSRRSNSGERLDHVPSQHPSREGLGPPPQLLRVREDPASGPSPSTEQLDILSSILASFNSSALSVQSSSTPSGPHTTATPSATASALGPSTPRSATSHSISELSPDSEVPRSEGHS", "length": 3302, "header": "tr|A0A5G2R732-1|A0A5G2R732_PIG Isoform 1 of Cadherin EGF LAG seven-pass G-type receptor 3 OS=Sus scrofa OX=9823 GN=CELSR3 PE=3 SV=1 CANONICAL=A0A5G2R732-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R732-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732/entry#A0A5G2R732-1", "sequence": { "sequence": "MARRQPWWGLWGPMTPLLLFLLLLSLFPLSREELGGDGGQDWGPGVAAATGPGARIGGGALALCPEPPGVREDGKPGLGVKEPVFVGLQGGRQSTQNGRGPPEEPRLVAEFGVQAVGSRGRETGQGPGSLLCWRPEVSSCRRTGPLQRDSLSPEALSPGVPGPENSSPFPSDFLVRTRGSQPVFSQRNTGRGALKKVGTTRCCGELWAPGRRGQSERTATSRPDRPPGAVGSSPVLDSAPRTGRTALASGSAPRVSRTAPEPMPERMRSRGLFRRRFLPQRPGPRPPGVPAGPGAWRIPSAGRVRPRRAANHHPQFPQYNYQALVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQSGLIRTEAALDRESMDRHYLRVTAQDHGSPRLSATTMVAVTVTDRNDHAPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHTPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDATVGTSVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRALHDHCYVHINITDANTHRPVFQSAHYSVKVNEDQPVGSTVVVISASDDDVGENARITYLLEDNLPQFRIDADSGAITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHVNGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRWLDREAVPVYELTAYAVDRGVPPLRTPVSIQVTVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQEYVIVVQATSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPDVSDHLFYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVIITEELLANSLTVRLENMWQERFLSPLLGHFLEGVAAVLATPAEDVFIFNIQNDTDVGGTVLNVSFSALAPRGAGAGSAGPWFSSEELQEQLYVRRAALAARSLLDVLPFDDNVCLREPCENYMKCVSVLRFDSSAPFLASASTLFRPIQPIAGLRCRCPPGFTGDFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCADGPDGGFRCQCPAGGAFEGPRCEVAARSFPPSSFVMFRGLRQRFHLTLSLSFATVQPSGLLFYNGRLNEKHDFLALELVAGQVRLTYSTGESNTVVSPTVPGGLSDGQWHTVHLRYYNKPRTDALGGAQGPSKDKVAVLSVDDCDVAVALQFGAEIGNYSCAAAGTQTSSKKSLDLTGPLLLGGVPNLPENFPVSHKDFVGCMRDLHIDGRQVDMAGFVANNGTMAGCQAKLHFCDSGPCKNSGFCSERWGGFSCDCPVGFGGKDCRLTMAHPHHFRGNGTLSWDFGNDMAVSVPWYLGLAFRTRATQGVLMQVQAGPHSTLLCQLDRGLLSVTVTKGSGRAAHLLLDEVTVSDGRWHDLRLELQEEPGGRRGHHVLMVSLDFSLFQDTLAVGSELQGLKVKRLHVGGLPPGSEEEAPQGLVGCIQGVWLGSTPLGSPALLPPSHRVNVEPGCVVTNACASGPCPPHADCRDLWQTFSCTCWPGYYGPGCVDACLLNPCQNQGSCRHLPGAPLGYTCDCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDLCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTASGCQVLYDACPKSLRSGVWWPQTKFGVLASVPCPRGALGAAVRLCDEDQGWLEPDLFNCTSPAFRELNLLLDGLELNKTVLDTVEAKKLAQRLREVTGHTDHYFSQDVRVTARLLAHLLAFESHQQGFGLTATQDAHFNENLLWAGSALLAPETGDLWAALGQRSPGGSPGSAGLVQHLEEYAATLARNMELTYLNPVGLVTPNIMLSIDRMEHPSPTRGTRRYPRYHSNLFRGQDAWDPHTHVLLPSQAPRPSSPEVLSTSSSTENSTTSSLAPPPVPLDPEPEPGISIVILLVYRTLGGLLPAQFQAERRGARLPQNPVMNSPVVSVAVFHGRNFLRGVLESPISLEFRLLQTANRSKAICVQWDPPGPADQHGMWTARDCELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVMAVSVAALLLTAAILLSLRSLKSNIRGIHANVAAALGVAELLFLLGIHRTQNQLVCTVVAILLHYFFLSTFAWLLVQGLHLYRMQVEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEGYGNPDFCWISVHEPLIWSFAGPVVLVIMMNGTLFLLAARTSCSTGQREAKKTSVLTLRSSFLLLLLVSASWLFGLLAVNHSILAFHYLHAGLCGLQGLVVLLLFCVLNADARAAWTPACLGRKAVPEEARPAPGTGPGAYNNTALFEESGLIRITLGASTISSVSSARSGRTQDQDSQRGRSYLRDNVLVRHGSAADHTDHSLQAHAGPTDLDVAMFHRDAGADSDSDSDLSLEEERSLSIPSSESEDNGRAQGRFQRPLHRAAQSERLLTHPKDMDGNDLLSYWPALGECEAAPCALQTWGSERRLGLDTSKDAANNNQPDLALTSGDETSLGRAQRQRKGILKNRLQYPLVPQTRGTPELSWCRAATLGHRAVPAASYGRIYAGGGTGSLSQPASRYSSREQLDLLLRRQLSREQLEEAPAPVLRPLSRPGSQEHLDAMPGRLEPRDRGSTLPRRQPPRDYPGTMAACFGSRDALDQGAPCEWLSTLPPPHGVQDLDPQPPPLPLSPQRQLSRDPLLPSRPLDSLSRRSNSGERLDHVPSQHPSREGLGPPPQLLRVREDPASGPSPSTEQLDILSSILASFNSSALSVQSSSTPSGPHTTATPSATASALGPSTPRSATSHSISELSPDSEVPRSEGHS", "length": 3302, "header": "tr|A0A5G2R732-1|A0A5G2R732_PIG Isoform 1 of Cadherin EGF LAG seven-pass G-type receptor 3 OS=Sus scrofa OX=9823 GN=CELSR3 PE=3 SV=1 CANONICAL=A0A5G2R732-1" }, "locus": { "chromosome": "13", "start_pos": 31357270, "end_pos": 31333325, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091456.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091456.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066411.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066411.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1006, "start_aa": "Thr", "end_pos": 1006, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1006", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1296, "start_aa": "Thr", "end_pos": 1296, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1296", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1581, "start_aa": "Thr", "end_pos": 1581, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1581", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3256, "start_aa": "Thr", "end_pos": 3256, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3256", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R732", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R732", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R732", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R732", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R732", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R732", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R732", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R732", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R732", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1173, "end_pos": 1175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1213, "end_pos": 1215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1308, "end_pos": 1310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1318, "end_pos": 1320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1640, "end_pos": 1642, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1704, "end_pos": 1706, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1761, "end_pos": 1763, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2044, "end_pos": 2046, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2168, "end_pos": 2170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2187, "end_pos": 2189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2377, "end_pos": 2379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2467, "end_pos": 2469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2499, "end_pos": 2501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2690, "end_pos": 2692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2739, "end_pos": 2741, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2801, "end_pos": 2803, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3245, "end_pos": 3247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 317, "end_pos": 424, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 1366, "end_pos": 1424, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" }, { "id": "PS50227", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 1", "eco_id": "ECO_0000259", "start_pos": 2100, "end_pos": 2173, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" }, { "id": "PS50261", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 2", "eco_id": "ECO_0000259", "start_pos": 2532, "end_pos": 2768, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" }, { "id": "PS50221", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50221" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GAIN-B", "eco_id": "ECO_0000259", "start_pos": 2359, "end_pos": 2523, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" }, { "id": "PS50027", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50027" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin EGF-like", "eco_id": "ECO_0000259", "start_pos": 2068, "end_pos": 2115, "start_aa": "Cys", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R732" }, { "id": "PS50025", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50025" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin G", "eco_id": "ECO_0000259", "start_pos": 1506, "end_pos": 1710, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1006, 1296, 1581, 3256 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1173, "end_pos": 1175 }, { "start_pos": 1213, "end_pos": 1215 }, { "start_pos": 1308, "end_pos": 1310 }, { "start_pos": 1318, "end_pos": 1320 }, { "start_pos": 1640, "end_pos": 1642 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 1704, "end_pos": 1706 }, { "start_pos": 1761, "end_pos": 1763 }, { "start_pos": 2044, "end_pos": 2046 }, { "start_pos": 2168, "end_pos": 2170 }, { "start_pos": 2187, "end_pos": 2189 }, { "start_pos": 2377, "end_pos": 2379 }, { "start_pos": 2467, "end_pos": 2469 }, { "start_pos": 2499, "end_pos": 2501 }, { "start_pos": 2690, "end_pos": 2692 }, { "start_pos": 2739, "end_pos": 2741 }, { "start_pos": 2801, "end_pos": 2803 }, { "start_pos": 3245, "end_pos": 3247 }, { "start_pos": 623, "end_pos": 625 }, { "start_pos": 838, "end_pos": 840 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R744-1", "uniprot_ac": "A0A5G2R744", "uniprot_id": "A0A5G2R744_PIG", "mass": { "chemical_mass": 43795.0, "monoisotopic_mass": 43795.0 }, "refseq": {}, "gene_names": [ { "name": "PPME1", "type": "recommended", "evidence": [ { "id": "A0A5G2R744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744" } ] } ], "protein_names": [ { "name": "Protein phosphatase methylesterase 1", "type": "recommended", "evidence": [ { "id": "A0A5G2R744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.-", "type": "synonym", "evidence": [ { "id": "A0A5G2R744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744/entry#names_and_taxonomy" } ] }, { "name": "PME-1", "type": "synonym", "evidence": [ { "id": "A0A5G2R744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.", "evidence": [ { "database": "UniProtKB", "id": "I3LJT9", "url": "https://www.uniprot.org/uniprotkb/I3LJT9#function" }, { "database": "UniProtKB", "id": "ARBA00024698", "url": "https://www.uniprot.org/uniprotkb/ARBA00024698#function" }, { "database": "UniProtKB", "id": "A0A5G2R744", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R744", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PPME1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744", "locus": { "chromosome": "9", "start_pos": 8605268, "end_pos": 8513141, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000020856", "url": "https://www.ensembl.org/id/ENSSSCG00000020856" } ] } } ], "crossref": [ { "id": "A0A5G2R744", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R744", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000020856", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000020856", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14189:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14189:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-69273", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69273", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "48548", "url": "https://www.rhea-db.org/rhea/48548", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R744", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R744-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LJT9", "url": "https://www.uniprot.org/uniprotkb/I3LJT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LJT9-1", "url": "https://www.uniprot.org/uniprotkb/I3LJT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSPVPWSQYFESMEDVEVENETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRGHGETKVKNSEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTSSNLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESVNKRKKEDDMEGLPSETQHLLLFLQTKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAVATFLIRHRFAEPIGGFQCVFPGC", "length": 399, "header": "tr|A0A5G2R744-1|A0A5G2R744_PIG Isoform 1 of Protein phosphatase methylesterase 1 OS=Sus scrofa OX=9823 GN=PPME1 PE=1 SV=1 CANONICAL=A0A5G2R744-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R744-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744/entry#A0A5G2R744-1", "sequence": { "sequence": "MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSPVPWSQYFESMEDVEVENETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRGHGETKVKNSEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTSSNLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESVNKRKKEDDMEGLPSETQHLLLFLQTKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAVATFLIRHRFAEPIGGFQCVFPGC", "length": 399, "header": "tr|A0A5G2R744-1|A0A5G2R744_PIG Isoform 1 of Protein phosphatase methylesterase 1 OS=Sus scrofa OX=9823 GN=PPME1 PE=1 SV=1 CANONICAL=A0A5G2R744-1" }, "locus": { "chromosome": "9", "start_pos": 8604067, "end_pos": 8513253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091522.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091522.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073072.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073072.1" } ] } }, { "isoform_ac": "I3LJT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744/entry#I3LJT9-1", "sequence": { "sequence": "MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSPVPWSQYFESMEDVEVENETGKDISFAEWLSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRGHGETVPAFFPSLCRDVGNVVEAMYGDLPPPIILLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESVNKRKKEDDMEGLPSETQHLLLFLQTKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAVATFLIRHRFAEPIGGFQW", "length": 369, "header": "tr|I3LJT9-1|A0A5G2R744_PIG Computationally mapped isoform of Protein phosphatase methylesterase 1 OS=Sus scrofa OX=9823 GN=PPME1 PE=1 SV=4 CANONICAL=A0A5G2R744-1" }, "locus": { "chromosome": "9", "start_pos": 8602768, "end_pos": 8513253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027793.4", "url": "https://www.ensembl.org/id/ENSSSCT00000027793.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024351.4", "url": "https://www.ensembl.org/id/ENSSSCP00000024351.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LJT9", "url": "https://www.uniprot.org/uniprotkb/I3LJT9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-69273", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69273", "resource": "Reactome", "description": "Cyclin A/B1/B2 associated events during G2/M transition" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R744", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein phosphatase 2A binding", "id": "GO:0051721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051721", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R744", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744" } ], "pmid": "" }, { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R744", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744" } ], "pmid": "" }, { "name": "protein methylesterase activity", "id": "GO:0051723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R744", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744" } ], "pmid": "" }, { "name": "lncRNA binding", "id": "GO:0106222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106222", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R744", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48548", "name": "", "equation": "[phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + methanol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "48548", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48548" } ] }, { "id": "R-SSC-8856951", "name": "PP2A demethylation by PPME1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-ALL-8857797" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8856951", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856951" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8857797", "participant_name": "methanol [nucleoplasm]", "crossref": [ { "id": "C00132", "database": "COMPOUND", "url": "" }, { "id": "17790", "database": "ChEBI", "url": "" }, { "id": "HMDB0001875", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R744-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 399, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R744-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R744" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R744" }, { "id": "PF00561", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AB hydrolase-1", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 369, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R753-1", "uniprot_ac": "A0A5G2R753", "uniprot_id": "A0A5G2R753_PIG", "mass": { "chemical_mass": 7307.0, "monoisotopic_mass": 7307.0 }, "refseq": { "ac": "NP_001422288", "name": "G protein subunit gamma 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422288" }, "gene_names": [ { "name": "GNG10", "type": "recommended", "evidence": [ { "id": "A0A5G2R753", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753" } ] }, { "name": "GNG10", "type": "synonym", "evidence": [ { "id": "NP_001422288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422288" } ] } ], "protein_names": [ { "name": "Guanine nucleotide-binding protein subunit gamma", "type": "recommended", "evidence": [ { "id": "A0A5G2R753", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753/entry#names_and_taxonomy" } ] }, { "name": "G protein subunit gamma 10", "type": "synonym", "evidence": [ { "id": "NP_001422288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422288" } ] } ], "function": [ { "annotation": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Interacts with beta-1 and beta-2, but not with beta-3.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R753", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753#function" }, { "database": "UniProtKB", "id": "ARBA00057705", "url": "https://www.uniprot.org/uniprotkb/ARBA00057705#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R753", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GNG10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753", "locus": { "chromosome": "1", "start_pos": 252460315, "end_pos": 252453107, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000046439", "url": "https://www.ensembl.org/id/ENSSSCG00000046439" } ] } } ], "crossref": [ { "id": "A0A5G2R753", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R753", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000046439", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000046439", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00068", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00068", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515992", "url": "https://www.ncbi.nlm.nih.gov/gene/100515992", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YREPRSC", "url": "https://omabrowser.org/oma/group/YREPRSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1296041", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296041", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-202040", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202040", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-392170", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-392451", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392451", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4086398", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4086398", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418597", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-428930", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-428930", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-456926", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-456926", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6814122", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6814122", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8964616", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-997272", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001422288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422288", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R753", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R753-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSGASVSALQRLVEQLKLEASVERIKVSQAAAELQQYCMQNACKDALLVGIPTGSNPFREPRSCALL", "length": 68, "header": "tr|A0A5G2R753-1|A0A5G2R753_PIG Isoform 1 of Guanine nucleotide-binding protein subunit gamma OS=Sus scrofa OX=9823 GN=GNG10 PE=1 SV=1 CANONICAL=A0A5G2R753-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R753-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753/entry#A0A5G2R753-1", "sequence": { "sequence": "MSSGASVSALQRLVEQLKLEASVERIKVSQAAAELQQYCMQNACKDALLVGIPTGSNPFREPRSCALL", "length": 68, "header": "tr|A0A5G2R753-1|A0A5G2R753_PIG Isoform 1 of Guanine nucleotide-binding protein subunit gamma OS=Sus scrofa OX=9823 GN=GNG10 PE=1 SV=1 CANONICAL=A0A5G2R753-1" }, "locus": { "chromosome": "1", "start_pos": 252457752, "end_pos": 252453123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069089.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069089.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072165.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072165.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R753", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1296041", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296041", "resource": "Reactome", "description": "Activation of G protein gated Potassium channels" }, { "id": "R-SSC-202040", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202040", "resource": "Reactome", "description": "G-protein activation" }, { "id": "R-SSC-392170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392170", "resource": "Reactome", "description": "ADP signalling through P2Y purinoceptor 12" }, { "id": "R-SSC-392451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392451", "resource": "Reactome", "description": "G beta:gamma signalling through PI3Kgamma" }, { "id": "R-SSC-4086398", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4086398", "resource": "Reactome", "description": "Ca2+ pathway" }, { "id": "R-SSC-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-SSC-418597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418597", "resource": "Reactome", "description": "G alpha (z) signalling events" }, { "id": "R-SSC-428930", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-428930", "resource": "Reactome", "description": "Thromboxane signalling through TP receptor" }, { "id": "R-SSC-456926", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-456926", "resource": "Reactome", "description": "Thrombin signalling through proteinase activated receptors (PARs)" }, { "id": "R-SSC-6814122", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6814122", "resource": "Reactome", "description": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" }, { "id": "R-SSC-8964616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964616", "resource": "Reactome", "description": "G beta:gamma signalling through CDC42" }, { "id": "R-SSC-997272", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "resource": "Reactome", "description": "Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits" } ], "orthologs": [ { "uniprot_canonical_ac": "P50151-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10", "gene_name": "GNG10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFREPRSCALL", "length": 68 }, "evidence": [ { "id": "A0A5G2R753", "url": "https://omabrowser.org/oma/group/A0A5G2R753/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CXP8-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10", "gene_name": "Gng10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSGASVSALQRLVEQLKLEAGVERIKVSQAAAELQQYCIQNACKDALLLGVPAGSNPFREPRSCALL", "length": 68 }, "evidence": [ { "id": "A0A5G2R753", "url": "https://omabrowser.org/oma/group/A0A5G2R753/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G-protein beta-subunit binding", "id": "GO:0031681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031681", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R753", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R753", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "heterotrimeric G-protein complex", "id": "GO:0005834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005834", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R753", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R753-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 68, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R753-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R753" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R753", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R753" }, { "id": "PS50058", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50058" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G protein gamma", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 68, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R780-1", "uniprot_ac": "A0A5G2R780", "uniprot_id": "A0A5G2R780_PIG", "mass": { "chemical_mass": 476174.0, "monoisotopic_mass": 476174.0 }, "refseq": { "ac": "XP_020942964", "name": "dynein heavy chain 6, axonemal isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942964" }, "gene_names": [ { "name": "DNAH6", "type": "recommended", "evidence": [ { "id": "A0A5G2R780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ] }, { "name": "DNAH6", "type": "synonym", "evidence": [ { "id": "XP_020942964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942964" } ] } ], "protein_names": [ { "name": "Dynein axonemal heavy chain 6", "type": "synonym", "evidence": [ { "id": "A0A5G2R780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780/entry#names_and_taxonomy" } ] }, { "name": "dynein heavy chain 6, axonemal isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020942964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942964" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DNAH6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780", "locus": { "chromosome": "3", "start_pos": 59859863, "end_pos": 60114365, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000045529", "url": "https://www.ensembl.org/id/ENSSSCG00000045529" } ] } } ], "crossref": [ { "id": "ENSSSCG00000045529", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045529", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00009", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00009", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524798", "url": "https://www.ncbi.nlm.nih.gov/gene/100524798", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524798", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524798", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R780", "url": "https://www.orthodb.org/?gene=A0A5G2R780", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22878", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22878", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22878:SF67", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22878:SF67", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12774", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12774", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12781", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17852", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17852", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18199", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18199", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020942964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942964", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R780-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFHASENDLDLKNIGELVENPVLSRLNSIKAKGRLSYVIPMENEADKQFLTFKNTTKAQERTRKRQQPVKLEPLPVLKVYQDHKKPEYIYDQNRYQLIASGILKPPGSTEERSSAKSLVQFLEHEDSVKKKKQLQWPSAEAFTPTPPKQLRTSIGRRGLYETSSSTYPKYYFHDREEVVKANIQNPLQIIKIVRENEHIGFLYMIPAVPRSSIEYDTYNLKVVNYENINKNDYYTISKKAITHIYNDDIEFIEIDRWEQEYLYHRELTKIPIFSLFRKWKAFNVWKKNVRSKKISGCRKSLQKNLFIVNHYLRPALLKINELCYQLSFMGLCCIEKCHTYTLHEFKVTQVIRLEEVTERLEEFRNEAKDVVRKACRVALRAAGFVPDDCVYEPVEGHLKRPESGSFIELPTSGDSEKMTYTEQASKRHHCMRLTCFIRLNDYLIENTMHVLTVNSASSLLNHLTDKLKRTPSADVIQKWITEEKPEVTDKKGAPMMEKQEEDESLTPMFLTELILTVQSLLFEPSLEDFLDGISGAINHFQSTVLSVPNLVPDPYFDAFTSPYINNKLEEKTCGFGPSLSAVFDDDMNFHTIIYQIKEAVQAAFESAQLYAATFEKFQIFFKENESLDLQALKLQEPDVKFFSEQLEKYHREHKEAVALRPTRNVGLLLIDTKQLKEKLIPSPLRCLEVLNYMLPRQSKKKVDAIISEAQDAEYKLEFVPTTTIEYVNNLVFLDEIQERIESLEDEGNIVIQMYKLIEQYQVPTPPEDFAVFATMKPSIVAVRNAIDKSVGDREASIKQFCLHLGRDLEDLSNEVNEIKLQAQDPQILDINADPDKIKVILNDLQLVLDDLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSLSEWDQLQQEWLKSKFDCLDPEFLNSQVSKYAKFVTQLEKGLPPNSVVPQLKTKVEKMKEKLPVIMDLRNPTLKPRHWAAIEQTVDATLVDLDVPLTLDKLSELHVFDFGQEIQDISGQASGEAALETILKKVEDSWKTTEFVVLPHRDSKDVFILGGTDDIQVLLDDSTINIATIASSRYVGPLKTRVDDWQKQLALFNQTLEEWLNCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPTESKIPVIDAEPEKVYTNDILAMLSPEGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYLGKLRTEWVIAGHPSQVILTVSQIMWCRDMTDCLEKEDGNRLEALEAFENVNFERLNALAAIVRGSLPKLHRNIITALITIDVHARDIVTELVQAKVEAVESFDWQRQLRYYWDIDVDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPNLSEDVVLIRALRDSNLPKFLTDDAILFSGIISDLFPGVQIPEHDYGILQSTIIDVMNGQNLQPETCMVKKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLRKLGVDNPFYQPVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLKVASPATVSRCGMVFVDPEELKWMPYVKTWMKSVSKKLNEETQEYILNLFQRYVDDGLNFINKKCTQAIPQVDISKVTTLCCLLESLLLGKDGVNLAMEQAKLNTVLCQTFVFCYLWSLGGNLTENYWDSFDTFIRTQFDDNPDARLPSSGDLWSIHMDFDTKRLDPWERIIPTFKYSRDIPFFEMLVPTADTVRFGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNRIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNVLGAPGHKRVVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKDIQDVTILSACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLNDFTPAVKQTASNIVEASVEIYNRMSIDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHAILTEMANKHFGIAIGLEYFLTRPIIFGDFIKFGADKADRIYDDMPDMEKIANVLQDYLDDYNLINPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYRCLQIELSRGYNYDSFHEDLRKLYRLAGVEDRNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISRVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSNVDAVNEELREKLSFMCVNVHLSVSNMAERYYTELRRRYYTTPTSYLELINLYLSMLSEKKKQLVSARERVKNGLTKLLETNELVDKMKLDLSALEPVLLTKSQDVEALMDKLAVDQENADQVRNIVQEDEAIAKVKAEETQAIADDAQRDLEEALPALEAANKALDSLDKADISEIRVFTKPPDMVMTVMEAISILLNAKPDWPTAKQLLGDSNFLRRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKEVEPKRQKLRAAQAELDITMATLKEKQALLKQVEDQIQALQDEYDRSVNEKESLAKTMALTKARLVRAGKLTAALGDEHVRWEESIQKFDEEISDIIGNVFIAAACVAYYGAFTAQYRQSLIECWIQDCQSLEIPINPSFSLINTLGDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKNGLKIIKLTDSNFLRTLENSIRLGLPVLLEELRETLDPALEPILLKQTFISGGRLLIRLGDSDIDYDKNFKFYMTTKLPNPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPELEEQRIKLIVRINTDKNQLKAIEEKILKMLFTSEGNILDNEELIDTLQDSKITSGAIKIRLKEAESTEQMINIAREKYRPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVRTDDLQQRMEILLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVELMRQQGSLTDAEWNFFLRGSAGLEKERPPKPDFPWLVTAMWFACCDLEELFPVFKGLTQYIVLHPISIRIGSFETYINPNDGEAYSKMKEDDQLMTVERMTTNHDSWHPELSSFQKLILIKCCKEEKVVFALTDFVIENLGKSFIETPPVDLPTLYQDMSYNTPLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAERMIKDAMKTGNWVFLQNCHLAVSWMLAMEELIKTFTDSNVVIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRRAFTEMTPSFFEENILGRKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLNLYCQEGKIPWDALIYITGEITYGGRVTDTWDQRCLRTVLKRFFSPETLQEDYKYSESGIYFAPLSDSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETNTLINTILEVQPRSSSGEEGKSNDEIVQELVASVRTRVPETLEMDSASESLFVKDPQGRLNSLTTVLGQEVDRFNNLLKLIHTSLDTLNKAIAGLVVMSEEMEKVYNSFLNNQVPSLWSNTAYPSLKPLGSWVKDLILRTAFVDLWLKRGQPKSFWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYNVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDNKEMVIEDALPGQMNPMLPVVHFEPQQNYEPSPTLYHSPLYKTGARAGTLSTTGHSTNFVVTILLPSKRPKDYWIAKGSALLCQLNE", "length": 4155, "header": "tr|A0A5G2R780-1|A0A5G2R780_PIG Isoform 1 of Dynein axonemal heavy chain 6 OS=Sus scrofa OX=9823 GN=DNAH6 PE=3 SV=1 CANONICAL=A0A5G2R780-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R780-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780/entry#A0A5G2R780-1", "sequence": { "sequence": "MSFHASENDLDLKNIGELVENPVLSRLNSIKAKGRLSYVIPMENEADKQFLTFKNTTKAQERTRKRQQPVKLEPLPVLKVYQDHKKPEYIYDQNRYQLIASGILKPPGSTEERSSAKSLVQFLEHEDSVKKKKQLQWPSAEAFTPTPPKQLRTSIGRRGLYETSSSTYPKYYFHDREEVVKANIQNPLQIIKIVRENEHIGFLYMIPAVPRSSIEYDTYNLKVVNYENINKNDYYTISKKAITHIYNDDIEFIEIDRWEQEYLYHRELTKIPIFSLFRKWKAFNVWKKNVRSKKISGCRKSLQKNLFIVNHYLRPALLKINELCYQLSFMGLCCIEKCHTYTLHEFKVTQVIRLEEVTERLEEFRNEAKDVVRKACRVALRAAGFVPDDCVYEPVEGHLKRPESGSFIELPTSGDSEKMTYTEQASKRHHCMRLTCFIRLNDYLIENTMHVLTVNSASSLLNHLTDKLKRTPSADVIQKWITEEKPEVTDKKGAPMMEKQEEDESLTPMFLTELILTVQSLLFEPSLEDFLDGISGAINHFQSTVLSVPNLVPDPYFDAFTSPYINNKLEEKTCGFGPSLSAVFDDDMNFHTIIYQIKEAVQAAFESAQLYAATFEKFQIFFKENESLDLQALKLQEPDVKFFSEQLEKYHREHKEAVALRPTRNVGLLLIDTKQLKEKLIPSPLRCLEVLNYMLPRQSKKKVDAIISEAQDAEYKLEFVPTTTIEYVNNLVFLDEIQERIESLEDEGNIVIQMYKLIEQYQVPTPPEDFAVFATMKPSIVAVRNAIDKSVGDREASIKQFCLHLGRDLEDLSNEVNEIKLQAQDPQILDINADPDKIKVILNDLQLVLDDLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSLSEWDQLQQEWLKSKFDCLDPEFLNSQVSKYAKFVTQLEKGLPPNSVVPQLKTKVEKMKEKLPVIMDLRNPTLKPRHWAAIEQTVDATLVDLDVPLTLDKLSELHVFDFGQEIQDISGQASGEAALETILKKVEDSWKTTEFVVLPHRDSKDVFILGGTDDIQVLLDDSTINIATIASSRYVGPLKTRVDDWQKQLALFNQTLEEWLNCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPTESKIPVIDAEPEKVYTNDILAMLSPEGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYLGKLRTEWVIAGHPSQVILTVSQIMWCRDMTDCLEKEDGNRLEALEAFENVNFERLNALAAIVRGSLPKLHRNIITALITIDVHARDIVTELVQAKVEAVESFDWQRQLRYYWDIDVDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPNLSEDVVLIRALRDSNLPKFLTDDAILFSGIISDLFPGVQIPEHDYGILQSTIIDVMNGQNLQPETCMVKKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLRKLGVDNPFYQPVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLKVASPATVSRCGMVFVDPEELKWMPYVKTWMKSVSKKLNEETQEYILNLFQRYVDDGLNFINKKCTQAIPQVDISKVTTLCCLLESLLLGKDGVNLAMEQAKLNTVLCQTFVFCYLWSLGGNLTENYWDSFDTFIRTQFDDNPDARLPSSGDLWSIHMDFDTKRLDPWERIIPTFKYSRDIPFFEMLVPTADTVRFGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNRIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNVLGAPGHKRVVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKDIQDVTILSACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLNDFTPAVKQTASNIVEASVEIYNRMSIDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHAILTEMANKHFGIAIGLEYFLTRPIIFGDFIKFGADKADRIYDDMPDMEKIANVLQDYLDDYNLINPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYRCLQIELSRGYNYDSFHEDLRKLYRLAGVEDRNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISRVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSNVDAVNEELREKLSFMCVNVHLSVSNMAERYYTELRRRYYTTPTSYLELINLYLSMLSEKKKQLVSARERVKNGLTKLLETNELVDKMKLDLSALEPVLLTKSQDVEALMDKLAVDQENADQVRNIVQEDEAIAKVKAEETQAIADDAQRDLEEALPALEAANKALDSLDKADISEIRVFTKPPDMVMTVMEAISILLNAKPDWPTAKQLLGDSNFLRRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKEVEPKRQKLRAAQAELDITMATLKEKQALLKQVEDQIQALQDEYDRSVNEKESLAKTMALTKARLVRAGKLTAALGDEHVRWEESIQKFDEEISDIIGNVFIAAACVAYYGAFTAQYRQSLIECWIQDCQSLEIPINPSFSLINTLGDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKNGLKIIKLTDSNFLRTLENSIRLGLPVLLEELRETLDPALEPILLKQTFISGGRLLIRLGDSDIDYDKNFKFYMTTKLPNPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPELEEQRIKLIVRINTDKNQLKAIEEKILKMLFTSEGNILDNEELIDTLQDSKITSGAIKIRLKEAESTEQMINIAREKYRPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVRTDDLQQRMEILLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVELMRQQGSLTDAEWNFFLRGSAGLEKERPPKPDFPWLVTAMWFACCDLEELFPVFKGLTQYIVLHPISIRIGSFETYINPNDGEAYSKMKEDDQLMTVERMTTNHDSWHPELSSFQKLILIKCCKEEKVVFALTDFVIENLGKSFIETPPVDLPTLYQDMSYNTPLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAERMIKDAMKTGNWVFLQNCHLAVSWMLAMEELIKTFTDSNVVIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRRAFTEMTPSFFEENILGRKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLNLYCQEGKIPWDALIYITGEITYGGRVTDTWDQRCLRTVLKRFFSPETLQEDYKYSESGIYFAPLSDSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETNTLINTILEVQPRSSSGEEGKSNDEIVQELVASVRTRVPETLEMDSASESLFVKDPQGRLNSLTTVLGQEVDRFNNLLKLIHTSLDTLNKAIAGLVVMSEEMEKVYNSFLNNQVPSLWSNTAYPSLKPLGSWVKDLILRTAFVDLWLKRGQPKSFWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYNVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDNKEMVIEDALPGQMNPMLPVVHFEPQQNYEPSPTLYHSPLYKTGARAGTLSTTGHSTNFVVTILLPSKRPKDYWIAKGSALLCQLNE", "length": 4155, "header": "tr|A0A5G2R780-1|A0A5G2R780_PIG Isoform 1 of Dynein axonemal heavy chain 6 OS=Sus scrofa OX=9823 GN=DNAH6 PE=3 SV=1 CANONICAL=A0A5G2R780-1" }, "locus": { "chromosome": "3", "start_pos": 60112355, "end_pos": 59860038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067002.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067002.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069987.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069987.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 146, "start_aa": "Thr", "end_pos": 146, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr146", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1752, "start_aa": "Thr", "end_pos": 1752, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1752", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2220, "start_aa": "Thr", "end_pos": 2220, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2220", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2284, "start_aa": "Thr", "end_pos": 2284, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2284", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524798", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524798", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium movement involved in cell motility", "id": "GO:0060294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060294", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R780", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1092, "end_pos": 1094, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1494, "end_pos": 1496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1662, "end_pos": 1664, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1804, "end_pos": 1806, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1823, "end_pos": 1825, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2001, "end_pos": 2003, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2122, "end_pos": 2124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3187, "end_pos": 3189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3324, "end_pos": 3326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3354, "end_pos": 3356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3714, "end_pos": 3716, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R780" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 1461, "end_pos": 1564, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 146, 1752, 2220, 2284 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1092, "end_pos": 1094 }, { "start_pos": 1494, "end_pos": 1496 }, { "start_pos": 1662, "end_pos": 1664 }, { "start_pos": 1804, "end_pos": 1806 }, { "start_pos": 1823, "end_pos": 1825 }, { "start_pos": 2001, "end_pos": 2003 }, { "start_pos": 2122, "end_pos": 2124 }, { "start_pos": 3187, "end_pos": 3189 }, { "start_pos": 3324, "end_pos": 3326 }, { "start_pos": 3354, "end_pos": 3356 }, { "start_pos": 3714, "end_pos": 3716 }, { "start_pos": 55, "end_pos": 57 }, { "start_pos": 625, "end_pos": 627 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R788-1", "uniprot_ac": "A0A5G2R788", "uniprot_id": "A0A5G2R788_PIG", "mass": { "chemical_mass": 22665.0, "monoisotopic_mass": 22665.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "exodeoxyribonuclease III", "type": "recommended", "evidence": [ { "id": "A0A5G2R788", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788/entry#names_and_taxonomy" } ] }, { "name": "3.1.11.2", "type": "synonym", "evidence": [ { "id": "A0A5G2R788", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R788", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788", "locus": {} } ], "crossref": [ { "id": "A0A5G2R788", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R788", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000046184", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000046184", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09076", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09076", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22748", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22748", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22748:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22748:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R788", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R788-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAINNHLSIITLNVNGLNAPIKRHRVAEWIKRQKPSICCLQETHLRTKDTYRLKVKGWEKIFHANRHDRKAGVATLISDKVDFKTKDIRKDKEGHYLMIKGSIQGEDVTIVNIYAPNIGAPRYIQQILTDIKGDIDGNTIIVGDLLYSKDTPNCPILGLQHSFANYYVYLPQTFSGPKQLRIDLQGTTFKLRYKCCKL", "length": 198, "header": "tr|A0A5G2R788-1|A0A5G2R788_PIG Isoform 1 of exodeoxyribonuclease III OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R788-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R788-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788/entry#A0A5G2R788-1", "sequence": { "sequence": "MAINNHLSIITLNVNGLNAPIKRHRVAEWIKRQKPSICCLQETHLRTKDTYRLKVKGWEKIFHANRHDRKAGVATLISDKVDFKTKDIRKDKEGHYLMIKGSIQGEDVTIVNIYAPNIGAPRYIQQILTDIKGDIDGNTIIVGDLLYSKDTPNCPILGLQHSFANYYVYLPQTFSGPKQLRIDLQGTTFKLRYKCCKL", "length": 198, "header": "tr|A0A5G2R788-1|A0A5G2R788_PIG Isoform 1 of exodeoxyribonuclease III OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R788-1" }, "locus": { "chromosome": "6", "start_pos": 129725227, "end_pos": 129724634, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087679.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087679.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066466.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066466.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R788", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R788", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R788", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788" } ], "pmid": "" }, { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R788", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R788", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788" } ], "pmid": "" }, { "name": "DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0003906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003906", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R788", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788" } ], "pmid": "" }, { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R788", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788" } ], "pmid": "" }, { "name": "double-stranded DNA 3'-5' DNA exonuclease activity", "id": "GO:0008311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008311", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R788", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R788-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 198, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R788-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R788" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R788", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788" }, { "id": "PF03372", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endonuclease/exonuclease/phosphatase", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 147, "start_aa": "Ile", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A5G2R788", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788#function" }, { "id": "A0A5G2R788", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 13, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 13, "end_pos": 13, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R788", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788#function" }, { "id": "A0A5G2R788", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R788" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 42, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 42, "end_pos": 42, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7B2-1", "uniprot_ac": "A0A5G2R7B2", "uniprot_id": "A0A5G2R7B2_PIG", "mass": { "chemical_mass": 177426.0, "monoisotopic_mass": 177426.0 }, "refseq": {}, "gene_names": [ { "name": "VWDE", "type": "recommended", "evidence": [ { "id": "A0A5G2R7B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2" } ] } ], "protein_names": [ { "name": "von Willebrand factor D and EGF domains", "type": "synonym", "evidence": [ { "id": "A0A5G2R7B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7B2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "VWDE", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2", "locus": { "chromosome": "9", "start_pos": 81916966, "end_pos": 81986831, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000022543", "url": "https://www.ensembl.org/id/ENSSSCG00000022543" } ] } } ], "crossref": [ { "id": "ENSSSCG00000022543", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022543", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14949", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14949", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14949:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14949:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23283", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23283", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R7B2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGGIWMLTLVSLLLTPGKTPECSPGGYQFLQSPYRNVHFDSLHLQQSAIQDLICDNALSPGWYRFLLFDRPAKMPTECVEMNHCGTQAPIWLSLRDSETLPPPGEIKHLTACATWQFLFSTTKDCCLFQIPVSVRNCGKFFVYLLQPTQGCMGYCAEAISDENLYPCGPDEIESGGDCFRQLTASLPPPPPGRPEVVVEMIESRLFCRCTFDVSPTNNSVGFLITWSRLSSQEIKEELKQETTIQAFSLLELDGINLRLGDRIFCSASIFFLEKPHVQSLAIKSQEFFAGIKLQPELSTISEDGKEYQLRIESTVPIVCPEFSELDQECKISLKLTTVDEGKEERGLNLALSSCHVDLHQTSPCANGTCSHAFVYYTAITDFSQDGSRVTNIVVEPIANEDFLWNNYIPDSIQIRVKDVPTAYCYSFTDPHIITFDGRMYDNFKTGTFVLYKSMSRDFEVHVRQWDCGSLHYPVSCNCGFVAKEEGDVVTFDMCSGQLHESQPYLFVKSQDVTSNIKISESYLGRKVTIWFSSGAFIRADLSEWGMSLTIRAPSLDYRNTLGLCGTFDENQENDFHDKNGIKIDQTFNNRVAFINEWRILPGKSMFDIMPVSLPSPRKPSFCGCSLETTSLYPSSNPLETVSQSEIVSACKDLKHIKFASLIQDLDVTSEYINSEALGRGINKHTSREENNLDFFPHEKTSHVNLTNLDLNLQKHPGNEKQNALKSVDEGRHTQNQSNHSQEMRWDRQNRWKRQNFYEFLPLFAFQSLSQSDLEEFTYFFPEDHTEDVHPEFVPTWPTPSGLTEYSTLALCQETLAKSGIGRHCLAFLGKRLDSVIDMCVKDVLLKDDLSWAEAGVALLENECEKRILEEGKYNREEYRKSIQDILLVLKCPNLCSGHGQCMEWGCACSPGFSSYDCSDSHDKVPEIIELENDGFCNIRKYNCMLVRVFGQGFKESPSVKCEVTKLQYNSSKWVLGEAIYTHTVFRNSRTVDCQLPSNVQQSGAMALTGEKPIAKWQLKVSNDGYKFSNPKIMIIYDGACQVCGLYEKDSCTIKENVCIIDGLCYTEGDKNPTSPCSICRPEISKFTWSFLEKNQPPVIQIPQAKLQTFWGENFVYQFMAFDPEGFDIHFTLDSGPVGANVSSAGLLMWKTESQTPQQFILHVNDDCNAETTVMIEVIVKSCDCLNGGSCVSDIQFPPGSGAYLCVCLPGFQGDLCEEDVTECQLNPCGLGRCISGFQNYSCDCPPELKVETQFLNELTTHTVVLTSSDKSVTKEEDGKNADQRERHLKPTNGNTSAICRHPCGKNRECVAPNICKCKPGYSGSNCQIAVCHPDCKNHGKCIKPNICECPPGHGGATCDEEYCRPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGECLTPDVCQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPDGFFGAQCQNAVCHPPCKNGGHCIRNNVCTCPKGYTGRRCQKSICDPMCMNGGKCVGPNLCSCPSGWIGNQCNTPVCFQKCKNGGECIAPGICHCPVTWEGARCQIPICTQKCLYGGRCVLPNVCSCRTGYSGVKCEKKIQIKRH", "length": 1592, "header": "tr|A0A5G2R7B2-1|A0A5G2R7B2_PIG Isoform 1 of von Willebrand factor D and EGF domains OS=Sus scrofa OX=9823 GN=VWDE PE=4 SV=1 CANONICAL=A0A5G2R7B2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R7B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2/entry#A0A5G2R7B2-1", "sequence": { "sequence": "MPGGIWMLTLVSLLLTPGKTPECSPGGYQFLQSPYRNVHFDSLHLQQSAIQDLICDNALSPGWYRFLLFDRPAKMPTECVEMNHCGTQAPIWLSLRDSETLPPPGEIKHLTACATWQFLFSTTKDCCLFQIPVSVRNCGKFFVYLLQPTQGCMGYCAEAISDENLYPCGPDEIESGGDCFRQLTASLPPPPPGRPEVVVEMIESRLFCRCTFDVSPTNNSVGFLITWSRLSSQEIKEELKQETTIQAFSLLELDGINLRLGDRIFCSASIFFLEKPHVQSLAIKSQEFFAGIKLQPELSTISEDGKEYQLRIESTVPIVCPEFSELDQECKISLKLTTVDEGKEERGLNLALSSCHVDLHQTSPCANGTCSHAFVYYTAITDFSQDGSRVTNIVVEPIANEDFLWNNYIPDSIQIRVKDVPTAYCYSFTDPHIITFDGRMYDNFKTGTFVLYKSMSRDFEVHVRQWDCGSLHYPVSCNCGFVAKEEGDVVTFDMCSGQLHESQPYLFVKSQDVTSNIKISESYLGRKVTIWFSSGAFIRADLSEWGMSLTIRAPSLDYRNTLGLCGTFDENQENDFHDKNGIKIDQTFNNRVAFINEWRILPGKSMFDIMPVSLPSPRKPSFCGCSLETTSLYPSSNPLETVSQSEIVSACKDLKHIKFASLIQDLDVTSEYINSEALGRGINKHTSREENNLDFFPHEKTSHVNLTNLDLNLQKHPGNEKQNALKSVDEGRHTQNQSNHSQEMRWDRQNRWKRQNFYEFLPLFAFQSLSQSDLEEFTYFFPEDHTEDVHPEFVPTWPTPSGLTEYSTLALCQETLAKSGIGRHCLAFLGKRLDSVIDMCVKDVLLKDDLSWAEAGVALLENECEKRILEEGKYNREEYRKSIQDILLVLKCPNLCSGHGQCMEWGCACSPGFSSYDCSDSHDKVPEIIELENDGFCNIRKYNCMLVRVFGQGFKESPSVKCEVTKLQYNSSKWVLGEAIYTHTVFRNSRTVDCQLPSNVQQSGAMALTGEKPIAKWQLKVSNDGYKFSNPKIMIIYDGACQVCGLYEKDSCTIKENVCIIDGLCYTEGDKNPTSPCSICRPEISKFTWSFLEKNQPPVIQIPQAKLQTFWGENFVYQFMAFDPEGFDIHFTLDSGPVGANVSSAGLLMWKTESQTPQQFILHVNDDCNAETTVMIEVIVKSCDCLNGGSCVSDIQFPPGSGAYLCVCLPGFQGDLCEEDVTECQLNPCGLGRCISGFQNYSCDCPPELKVETQFLNELTTHTVVLTSSDKSVTKEEDGKNADQRERHLKPTNGNTSAICRHPCGKNRECVAPNICKCKPGYSGSNCQIAVCHPDCKNHGKCIKPNICECPPGHGGATCDEEYCRPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGECLTPDVCQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPDGFFGAQCQNAVCHPPCKNGGHCIRNNVCTCPKGYTGRRCQKSICDPMCMNGGKCVGPNLCSCPSGWIGNQCNTPVCFQKCKNGGECIAPGICHCPVTWEGARCQIPICTQKCLYGGRCVLPNVCSCRTGYSGVKCEKKIQIKRH", "length": 1592, "header": "tr|A0A5G2R7B2-1|A0A5G2R7B2_PIG Isoform 1 of von Willebrand factor D and EGF domains OS=Sus scrofa OX=9823 GN=VWDE PE=4 SV=1 CANONICAL=A0A5G2R7B2-1" }, "locus": { "chromosome": "9", "start_pos": 81986831, "end_pos": 81917253, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087673.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087673.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073137.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073137.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 799, "start_aa": "Thr", "end_pos": 799, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr799", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7B2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7B2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7B2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7B2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7B2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1141, "end_pos": 1143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1240, "end_pos": 1242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1295, "end_pos": 1297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 705, "end_pos": 707, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" }, { "start_pos": 970, "end_pos": 972, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 1179, "end_pos": 1218, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R7B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B2" }, { "id": "PS51233", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51233" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFD", "eco_id": "ECO_0000259", "start_pos": 423, "end_pos": 606, "start_aa": "Ala", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 799 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1141, "end_pos": 1143 }, { "start_pos": 1240, "end_pos": 1242 }, { "start_pos": 1295, "end_pos": 1297 }, { "start_pos": 218, "end_pos": 220 }, { "start_pos": 367, "end_pos": 369 }, { "start_pos": 705, "end_pos": 707 }, { "start_pos": 736, "end_pos": 738 }, { "start_pos": 739, "end_pos": 741 }, { "start_pos": 970, "end_pos": 972 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7C5-1", "uniprot_ac": "A0A5G2R7C5", "uniprot_id": "A0A5G2R7C5_PIG", "mass": { "chemical_mass": 35255.0, "monoisotopic_mass": 35255.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110256244", "type": "recommended", "evidence": [ { "id": "A0A5G2R7C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R7C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7C5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7C5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110256244", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5", "locus": {} } ], "crossref": [ { "id": "A0A5G2R7C5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7C5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R7C5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKGNTTLLTEFVLTGLTYQPEWQIPLFLLFLIIYLITLMGNLGLIALICNDPHLHIPMYLFLGNLAFVDAWLSSTVTPKMLVNFFTKNKMISFTECQVQFFSFAICVTTECFLLATMAYDRYVAICKPLLYPVIMNNRLCIWLLIWSFLGGLFHAIIHNAFLFRLTFCNSIIVHQIYCDIIPLFKISCTDPSINFLMVFIFSGSIQVFTILIVLVSYTLVLFTILKKKSMQGIRKAFSTCGAHLLSVSLYYGPLLFMYVRPASLQADAQDMVDSIFYSIIIPVLNPVIYSLRNKKVIDSLTKKLKSNA", "length": 309, "header": "tr|A0A5G2R7C5-1|A0A5G2R7C5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110256244 PE=3 SV=1 CANONICAL=A0A5G2R7C5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R7C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5/entry#A0A5G2R7C5-1", "sequence": { "sequence": "MEKGNTTLLTEFVLTGLTYQPEWQIPLFLLFLIIYLITLMGNLGLIALICNDPHLHIPMYLFLGNLAFVDAWLSSTVTPKMLVNFFTKNKMISFTECQVQFFSFAICVTTECFLLATMAYDRYVAICKPLLYPVIMNNRLCIWLLIWSFLGGLFHAIIHNAFLFRLTFCNSIIVHQIYCDIIPLFKISCTDPSINFLMVFIFSGSIQVFTILIVLVSYTLVLFTILKKKSMQGIRKAFSTCGAHLLSVSLYYGPLLFMYVRPASLQADAQDMVDSIFYSIIIPVLNPVIYSLRNKKVIDSLTKKLKSNA", "length": 309, "header": "tr|A0A5G2R7C5-1|A0A5G2R7C5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110256244 PE=3 SV=1 CANONICAL=A0A5G2R7C5-1" }, "locus": { "chromosome": "13", "start_pos": 162092362, "end_pos": 162091436, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081194.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081194.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070032.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070032.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7C5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7C5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7C5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7C5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7C5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7C5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7C5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7C5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7C5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7H7-1", "uniprot_ac": "A0A5G2R7H7", "uniprot_id": "A0A5G2R7H7_PIG", "mass": { "chemical_mass": 65648.0, "monoisotopic_mass": 65648.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100620540", "type": "recommended", "evidence": [ { "id": "A0A5G2R7H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7" } ] } ], "protein_names": [ { "name": "Tyrosine-protein phosphatase non-receptor type", "type": "recommended", "evidence": [ { "id": "A0A5G2R7H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "A0A5G2R7H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7H7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100620540", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7", "locus": {} } ], "crossref": [ { "id": "A0A5G2R7H7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7H7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026816", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026816", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09931", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09931", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46559:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46559:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R7H7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LMA3", "url": "https://www.uniprot.org/uniprotkb/I3LMA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LMA3-1", "url": "https://www.uniprot.org/uniprotkb/I3LMA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LQJ5", "url": "https://www.uniprot.org/uniprotkb/I3LQJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LQJ5-1", "url": "https://www.uniprot.org/uniprotkb/I3LQJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGDGRGHGGGRVGLTGWFHPNISGVEAEKLLLSRGQHGSFLARPSQSCPGGFTLSVRRHDEVTHIKIQSTGDYYDLYGGEKFATLAELVQHYTGQHGGLLRERGGAPVELRHPLGCQDPTSERWYHGHLSGKEAEKLLTEKGRPGSFLVRESQSKPGDFVLSVLTQLLDKADCQPRVTHIRIHFQGKYDVGGGEQFDTLGDLVEHYRKSPMVERSGAMVHLGQPLKATRIKAASIESRVQELNKVMDASEKAKQGFWEEFELLQQQECQLLHPRREGQRLENKPKNRYKNILPFDTTRVVLRDVDKNVPGADYINANYIRVSHGLGKLYIATQGCLQTTVAAFWAMVHQENTRVIVMTTREVERGRNKCFRYWPELHGSQGYGHLRVRNVAEHWAQGYCVRELQVWQPNQESQRVVKHYQYCSWPDHGVPAEPAGVLGFLDEVNRAQNSMPGAGPVVVHCSAGIGRTGTIIVIDILVDIVRRQGLDCDIDVPKTIQLVRRQRSGMVQTEAQYKFVYLALQRYIQGQQLRLREQEAGPVRGGASAGITMVTSGPSPQREPPKEHDSLNVGALPADRGCSPGPAPSPAPEA", "length": 590, "header": "tr|A0A5G2R7H7-1|A0A5G2R7H7_PIG Isoform 1 of Tyrosine-protein phosphatase non-receptor type OS=Sus scrofa OX=9823 GN=LOC100620540 PE=3 SV=2 CANONICAL=A0A5G2R7H7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R7H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7/entry#A0A5G2R7H7-1", "sequence": { "sequence": "MGGDGRGHGGGRVGLTGWFHPNISGVEAEKLLLSRGQHGSFLARPSQSCPGGFTLSVRRHDEVTHIKIQSTGDYYDLYGGEKFATLAELVQHYTGQHGGLLRERGGAPVELRHPLGCQDPTSERWYHGHLSGKEAEKLLTEKGRPGSFLVRESQSKPGDFVLSVLTQLLDKADCQPRVTHIRIHFQGKYDVGGGEQFDTLGDLVEHYRKSPMVERSGAMVHLGQPLKATRIKAASIESRVQELNKVMDASEKAKQGFWEEFELLQQQECQLLHPRREGQRLENKPKNRYKNILPFDTTRVVLRDVDKNVPGADYINANYIRVSHGLGKLYIATQGCLQTTVAAFWAMVHQENTRVIVMTTREVERGRNKCFRYWPELHGSQGYGHLRVRNVAEHWAQGYCVRELQVWQPNQESQRVVKHYQYCSWPDHGVPAEPAGVLGFLDEVNRAQNSMPGAGPVVVHCSAGIGRTGTIIVIDILVDIVRRQGLDCDIDVPKTIQLVRRQRSGMVQTEAQYKFVYLALQRYIQGQQLRLREQEAGPVRGGASAGITMVTSGPSPQREPPKEHDSLNVGALPADRGCSPGPAPSPAPEA", "length": 590, "header": "tr|A0A5G2R7H7-1|A0A5G2R7H7_PIG Isoform 1 of Tyrosine-protein phosphatase non-receptor type OS=Sus scrofa OX=9823 GN=LOC100620540 PE=3 SV=2 CANONICAL=A0A5G2R7H7-1" }, "locus": { "chromosome": "6", "start_pos": 63411297, "end_pos": 63405357, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086124.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086124.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066556.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066556.2" } ] } }, { "isoform_ac": "I3LMA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7/entry#I3LMA3-1", "sequence": { "sequence": "MVWFHPNISGVEAEKLLLSRGQHGSFLARPSQSCPGGFTLSVRWVGGGVTHIKIQSTGDYYDLYGGEKFATLAELVQHYTGQHGGLLRERGGAPVELRHPLGCQDPTSERWYHGHLSGKEAEKLLTEKGRPGSFLVRESQSKPGDFVLSVLTQLLDKADCQPRVTHIRIHFQGKYDVGGGEQFDTLGDLVEHYRKSPMVERSGAMVHLGQPLKATRIKAASIESRVQELNKVMDASEKAKQGFWEEFELLQQQECQLLHPRREGQRLENKPKNRYKNILPFDTTRVVLRDVDKNVPGADYINANYIRVSHGLGKLYIATQGCLQTTVAAFWAMVHQENTRVIVMTTREVERGRNKCFRYWPELHGSQGYGHLRVRNVAEHWAQGYCVRELQVWQPNQESQRVVKHYQYCSWPDHGVPAEPAGVLGFLDEVNRAQNSMPGAGPVVVHCSAGIGRTGTIIVIDILVDIVRRQGLDCDIDVPKTIQLVRRQRSGMVQTEAQYKFVYLALQRYIQGQQLRLREQEAGPVRGGASAGITMVTSGPSPQREPPKEHDSLNVGALPADRGCSPGPAPSPAPEA", "length": 576, "header": "tr|I3LMA3-1|A0A5G2R7H7_PIG Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type OS=Sus scrofa OX=9823 GN=LOC100620540 PE=3 SV=3 CANONICAL=A0A5G2R7H7-1" }, "locus": { "chromosome": "6", "start_pos": 63411297, "end_pos": 63404914, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026524.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026524.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025224.3", "url": "https://www.ensembl.org/id/ENSSSCP00000025224.3" } ] } }, { "isoform_ac": "I3LQJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7/entry#I3LQJ5-1", "sequence": { "sequence": "MSRGQHGSFLARPSQSCPGGFTLSVRWVGGGVTHIKIQSTGDYYDLYGGEKFATLAELVQHYTGQHGGLLRERGGAPVELRHPLGCQDPTSERWYHGHLSGKEAEKLLTEKGRPGSFLVRESQSKPGDFVLSVLTQLLDKADCQPRVTHIRIHFQGKYDVGGGEQFDTLGDLVEHYRKSPMVERSGAMVHLGQPLKATRIKAASIESRVQELNKVMDASEKAKQGFWEEFELLQQQECQLLHPRREGQRLENKPKNRYKNILPFDTTRVVLRDVDKNVPGADYINANYIRKPGHGLGKLYIATQGCLQTTVAAFWAMVHQENTRVIVMTTREVERGRNKCFRYWPELHGSQGYGHLRVRNVAEHWAQGYCVRELQVWQPNQESQRVVKHYQYCSWPDHGVPAEPAGVLGFLDEVNRAQNSMPGAGPVVVHCSAGIGRTGTIIVIDILVDIVRRQGLDCDIDVPKTIQLVRRQRSGMVQTEAQYKFVYLALQRYIQGQQLRLREQEAGPVRGGASAGITMVTKASGREYENLLGLRP", "length": 536, "header": "tr|I3LQJ5-1|A0A5G2R7H7_PIG Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type OS=Sus scrofa OX=9823 GN=LOC100620540 PE=3 SV=5 CANONICAL=A0A5G2R7H7-1" }, "locus": { "chromosome": "6", "start_pos": 63411521, "end_pos": 63405826, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030737.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030737.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026375.4", "url": "https://www.ensembl.org/id/ENSSSCP00000026375.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LQJ5", "url": "https://www.uniprot.org/uniprotkb/I3LQJ5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ERBB signaling pathway", "id": "GO:0038127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038127", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7H7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7H7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7H7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7H7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7H7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine phosphatase activity", "id": "GO:0004726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004726", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7H7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7H7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7H7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 590, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7H7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7H7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 115, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R7H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 438, "end_pos": 514, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R7H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H7" }, { "id": "PS50055", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50055" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 257, "end_pos": 523, "start_aa": "Phe", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7I1-1", "uniprot_ac": "A0A5G2R7I1", "uniprot_id": "A0A5G2R7I1_PIG", "mass": { "chemical_mass": 39518.0, "monoisotopic_mass": 39518.0 }, "refseq": { "ac": "XP_020955661", "name": "opsin-5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955661" }, "gene_names": [ { "name": "OPN5", "type": "recommended", "evidence": [ { "id": "A0A5G2R7I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ] }, { "name": "OPN5", "type": "synonym", "evidence": [ { "id": "XP_020955661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955661" } ] } ], "protein_names": [ { "name": "Opsin-5", "type": "recommended", "evidence": [ { "id": "A0A5G2R7I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 136", "type": "synonym", "evidence": [ { "id": "A0A5G2R7I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor PGR12", "type": "synonym", "evidence": [ { "id": "A0A5G2R7I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1/entry#names_and_taxonomy" } ] }, { "name": "Neuropsin", "type": "synonym", "evidence": [ { "id": "A0A5G2R7I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1/entry#names_and_taxonomy" } ] }, { "name": "opsin-5", "type": "synonym", "evidence": [ { "id": "XP_020955661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955661" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OPN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1", "locus": { "chromosome": "7", "start_pos": 42527121, "end_pos": 42476125, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027863", "url": "https://www.ensembl.org/id/ENSSSCG00000027863" } ] } } ], "crossref": [ { "id": "A0A5G2R7I1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7I1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000027863", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027863", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15074", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15074", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626620", "url": "https://www.ncbi.nlm.nih.gov/gene/100626620", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002962", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002962", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626620", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626620", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MENTTWP", "url": "https://omabrowser.org/oma/group/MENTTWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R7I1", "url": "https://www.orthodb.org/?gene=A0A5G2R7I1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-419771", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-419771", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020955661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955661", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LTK7", "url": "https://www.uniprot.org/uniprotkb/I3LTK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LTK7-1", "url": "https://www.uniprot.org/uniprotkb/I3LTK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALNHTAPPPDERRPHYLREGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTVNLAICDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAVIWAYAAFWTTMPLVGLGDYAPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLVAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEDFRLHAVTTVRKSSAVLEIHQEV", "length": 353, "header": "tr|A0A5G2R7I1-1|A0A5G2R7I1_PIG Isoform 1 of Opsin-5 OS=Sus scrofa OX=9823 GN=OPN5 PE=3 SV=1 CANONICAL=A0A5G2R7I1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R7I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1/entry#A0A5G2R7I1-1", "sequence": { "sequence": "MALNHTAPPPDERRPHYLREGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTVNLAICDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAVIWAYAAFWTTMPLVGLGDYAPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLVAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEDFRLHAVTTVRKSSAVLEIHQEV", "length": 353, "header": "tr|A0A5G2R7I1-1|A0A5G2R7I1_PIG Isoform 1 of Opsin-5 OS=Sus scrofa OX=9823 GN=OPN5 PE=3 SV=1 CANONICAL=A0A5G2R7I1-1" }, "locus": { "chromosome": "7", "start_pos": 42507092, "end_pos": 42476125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071214.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071214.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072301.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072301.1" } ] } }, { "isoform_ac": "I3LTK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1/entry#I3LTK7-1", "sequence": { "sequence": "MALNHTAPPPDERRPHYLREGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTVNLAICDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAVIWAYAAFWTTMPLVGLGDYAPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLVAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEDFRLHAVTTVRKSSAVLEIHQESRYKFTSTCDLGRRSYSNGDCDKKYG", "length": 378, "header": "tr|I3LTK7-1|A0A5G2R7I1_PIG Computationally mapped isoform of Opsin-5 OS=Sus scrofa OX=9823 GN=OPN5 PE=3 SV=3 CANONICAL=A0A5G2R7I1-1" }, "locus": { "chromosome": "7", "start_pos": 42527121, "end_pos": 42476125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031870.3", "url": "https://www.ensembl.org/id/ENSSSCT00000031870.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027454.3", "url": "https://www.ensembl.org/id/ENSSSCP00000027454.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LTK7", "url": "https://www.uniprot.org/uniprotkb/I3LTK7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626620", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626620", "resource": "KEGG Pathway" }, { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-SSC-419771", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-419771", "resource": "Reactome", "description": "Opsins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SJU0-1", "protein_name": "Opsin-5", "gene_name": "OPN5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALNHTAPPPDERRPPYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTVNLAICDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGIWLKRKHAYICLAVIWAYAAFWTTMPLVGLGDYAPEPFGTSCTLDWWLAQASVGGQIFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEVKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEDFRLHTVTTVRKSSAVLEIHQESEE", "length": 355 }, "evidence": [ { "id": "A0A5G2R7I1", "url": "https://omabrowser.org/oma/group/A0A5G2R7I1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NEY2-1", "protein_name": "Opsin-5", "gene_name": "OPN5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGMASDCNSSSQEEYLPHYMQQEDPFASKLSREADIIAGFYLTVIGILSTLGNGYVIFMSSKRKKKLRPAEIMTVNLAVCDLGISVVGKPFSIISFFSHRWIFGWMGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICHLAYGTWLKRHHAFICLALIWAYATFWATVPFAGVGSYAPEPFGTSCTLDWWLAQASVAGQAFVLSILFFCLLFPTAVIVFSYVKIILKVKSSTKEVAHYDTRIQNSHILEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGQPDSVPIQFSVVPTLLAKSAAMYNPIIYQVIDCKFACCRSGGPKTLQKKSSLKESRMYTISSHRDSAALSGTQLEV", "length": 357 }, "evidence": [ { "id": "A0A5G2R7I1", "url": "https://omabrowser.org/oma/group/A0A5G2R7I1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6U736-1", "protein_name": "Opsin-5", "gene_name": "OPN5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALNHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEWE", "length": 354 }, "evidence": [ { "id": "A0A5G2R7I1", "url": "https://omabrowser.org/oma/group/A0A5G2R7I1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6VZZ7-1", "protein_name": "Opsin-5", "gene_name": "Opn5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALNHTALPQDERLPHYLRDEDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWFGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAVIWAYASFWTTMPLVGLGDYAPEPFGTSCTLDWWLAQASGGGQVFILSILFFCLLLPTAVIVFSYAKIIAKVKSSSKEVAHFDSRIHSSHVLEVKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYRFACCQAGGLRGTKKKSLEDFRLHTVTAVRKSSAVLEIHPESSSRFTSAHVMDGESHSNDGDCGKK", "length": 377 }, "evidence": [ { "id": "A0A5G2R7I1", "url": "https://omabrowser.org/oma/group/A0A5G2R7I1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" }, { "name": "phototransduction", "id": "GO:0007602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007602", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" }, { "name": "cellular response to light stimulus", "id": "GO:0071482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071482", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" }, { "name": "phototransduction, UV", "id": "GO:0007604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007604", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" }, { "name": "hyaloid vascular plexus regression", "id": "GO:1990384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990384", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" }, { "name": "positive regulation of wound healing", "id": "GO:0090303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090303", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" }, { "name": "entrainment of circadian clock by photoperiod", "id": "GO:0043153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043153", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" }, { "name": "cellular response to UV-A", "id": "GO:0071492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071492", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "11-cis retinal binding", "id": "GO:0005502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005502", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" }, { "name": "G protein-coupled photoreceptor activity", "id": "GO:0008020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7I1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 353, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7I1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7I1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 306, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7I8-1", "uniprot_ac": "A0A5G2R7I8", "uniprot_id": "A0A5G2R7I8_PIG", "mass": { "chemical_mass": 35708.0, "monoisotopic_mass": 35708.0 }, "refseq": { "ac": "XP_020925494", "name": "olfactory receptor 5H8-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925494" }, "gene_names": [ { "name": "LOC110256355", "type": "recommended", "evidence": [ { "id": "A0A5G2R7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8" } ] }, { "name": "LOC110256355", "type": "synonym", "evidence": [ { "id": "XP_020925494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925494" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5H8-like", "type": "synonym", "evidence": [ { "id": "XP_020925494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925494" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110256355", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8", "locus": {} } ], "crossref": [ { "id": "A0A5G2R7I8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7I8", "database": "AlphaFoldDB", "categories": [] }, { "id": "110256355", "url": "https://www.ncbi.nlm.nih.gov/gene/110256355", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110256355", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110256355", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R7I8", "url": "https://www.orthodb.org/?gene=A0A5G2R7I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020925494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925494", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R7I8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METKNVTELTEFILSGLKYQSEWQIPLFLLFLMIYLITLMGNLGLIALICNNPQLHIPMYFFLGHLAFVDTWLSSTVTPKMLINFFAQSKMISFSECVVQFFSFVVSVTTECFLLATMAYDRYVAICNPLLYPVIISNRLCMRILVSSYIGGLLHAFIHTGFLFRLTFCNSNIVHHFYCDVMPLIKISCTDPSVNVLMLFIFSGSIQVFTILTVLVSYTFVLFTILKNKSVQSIRKAFSTCGSHLVSVSLYYGPLLFMYVRPGSTQGGDQDMMDSLFYTVIIPFLNPIIYSLRNKKVIDTLKKVLKKYGYVSN", "length": 313, "header": "tr|A0A5G2R7I8-1|A0A5G2R7I8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110256355 PE=3 SV=1 CANONICAL=A0A5G2R7I8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R7I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8/entry#A0A5G2R7I8-1", "sequence": { "sequence": "METKNVTELTEFILSGLKYQSEWQIPLFLLFLMIYLITLMGNLGLIALICNNPQLHIPMYFFLGHLAFVDTWLSSTVTPKMLINFFAQSKMISFSECVVQFFSFVVSVTTECFLLATMAYDRYVAICNPLLYPVIISNRLCMRILVSSYIGGLLHAFIHTGFLFRLTFCNSNIVHHFYCDVMPLIKISCTDPSVNVLMLFIFSGSIQVFTILTVLVSYTFVLFTILKNKSVQSIRKAFSTCGSHLVSVSLYYGPLLFMYVRPGSTQGGDQDMMDSLFYTVIIPFLNPIIYSLRNKKVIDTLKKVLKKYGYVSN", "length": 313, "header": "tr|A0A5G2R7I8-1|A0A5G2R7I8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110256355 PE=3 SV=1 CANONICAL=A0A5G2R7I8-1" }, "locus": { "chromosome": "13", "start_pos": 161791601, "end_pos": 161790663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083254.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083254.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070097.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070097.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110256355", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110256355", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7I8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7I8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7I8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7I8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7I8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 228, "end_pos": 230 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7L8-1", "uniprot_ac": "A0A5G2R7L8", "uniprot_id": "A0A5G2R7L8_PIG", "mass": { "chemical_mass": 34733.0, "monoisotopic_mass": 34733.0 }, "refseq": { "ac": "XP_003123629", "name": "olfactory receptor 2T8-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123629" }, "gene_names": [ { "name": "LOC110259752", "type": "recommended", "evidence": [ { "id": "A0A5G2R7L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8" } ] }, { "name": "LOC100520723", "type": "synonym", "evidence": [ { "id": "XP_003123629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123629" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R7L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2T8-like", "type": "synonym", "evidence": [ { "id": "XP_003123629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123629" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259752", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8", "locus": {} } ], "crossref": [ { "id": "A0A5G2R7L8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7L8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110259752", "url": "https://www.ncbi.nlm.nih.gov/gene/110259752", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520723", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520723", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ssc:110259752", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259752", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WKLCLSM", "url": "https://omabrowser.org/oma/group/WKLCLSM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R7L8", "url": "https://www.orthodb.org/?gene=A0A5G2R7L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003123629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123629", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R7L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENWNLTSDFILLGLFNHTGPHLFLFVMVLTTAFTSLVGNALMLLLILLDPQLHRPMYFLLSQLSLMDMMLVSTVVPKMAADYLTGRNSISPAGCGLQIFFFLTLGGGECFLLAAMSYDRYVAICHPLRYPVLMSWQICLRMILGSWFLGAADGLMQAAATLTFSYCSSHEIDHFFCEAPSLVHLACADTSLFESVMYICCVLMLLVPISLILISYSLILTTVLQMRSNEARKKAFATCSSHLSVVGLFFGAGIFTYMKPKSYRSANHDKIVSAFYTIFTPVLNPLIYSLRNSEVKGALKKCIDQCVALNHD", "length": 312, "header": "tr|A0A5G2R7L8-1|A0A5G2R7L8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259752 PE=3 SV=1 CANONICAL=A0A5G2R7L8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R7L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8/entry#A0A5G2R7L8-1", "sequence": { "sequence": "MENWNLTSDFILLGLFNHTGPHLFLFVMVLTTAFTSLVGNALMLLLILLDPQLHRPMYFLLSQLSLMDMMLVSTVVPKMAADYLTGRNSISPAGCGLQIFFFLTLGGGECFLLAAMSYDRYVAICHPLRYPVLMSWQICLRMILGSWFLGAADGLMQAAATLTFSYCSSHEIDHFFCEAPSLVHLACADTSLFESVMYICCVLMLLVPISLILISYSLILTTVLQMRSNEARKKAFATCSSHLSVVGLFFGAGIFTYMKPKSYRSANHDKIVSAFYTIFTPVLNPLIYSLRNSEVKGALKKCIDQCVALNHD", "length": 312, "header": "tr|A0A5G2R7L8-1|A0A5G2R7L8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259752 PE=3 SV=1 CANONICAL=A0A5G2R7L8-1" }, "locus": { "chromosome": "2", "start_pos": 55493062, "end_pos": 55492127, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075026.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075026.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070127.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070127.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520723", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520723", "resource": "KEGG Pathway" }, { "id": "ssc:110259752", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259752", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3MZ81-1", "protein_name": "Olfactory receptor", "gene_name": "OR2T60", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MENWNITADFILLGLFNHTGAHRFLFVLVLIVAFTSLVGNALMLLLILLDPRLHRPMYFLLSQLSLMDLMLISTIVPKMAVDYLTGRKFISPAGCGFQIFFFLTLGGGECFLLAAMSYDRYVAICHPLRYPVLMSWKVCLSMILGSWFLGAVDGLMQAAATLNFSFCSTHEIDHFFCEAPTLVRLACADTSVFEYVMYICCVLMLLIPMSLILISYSLILAAVLQMHSNEARRKAFATCSSHISVVGLFFGAAIFTYMRPKSYRSAKHDKFVSAFYTIFTPMLNPLIYSVRNSEVKGALRKCMDQCTALSLD", "length": 312 }, "evidence": [ { "id": "A0A5G2R7L8", "url": "https://omabrowser.org/oma/group/A0A5G2R7L8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7TRZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or2t44", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRGNTTAGFVLLGLFNHTRAHLFLFVLVLTVAFNSVVGNALLLLLIHQDRRLHTPMYFLLSQLSLMDMMLVSTVVPQMAAGYLMGKKFISAAGCGFQIFFFLTLGGGECFLLAAMSYDRYVAICHPLRYPVLMSWQLCLRLTVASWLLGAADGAMQAAATLSFQFCSRNEIDHFFCEAPVLLRLACGDTSAFEFFMYICCVLMLLIPFSLILMSYGLILAAVLRMRSTEARKKAFATCSSHLAVVGLFYGAATFSYMRPTSSRSANHDKVVSAFYTIVTPMLNPLIYSLRNSEVKGSLRKCVTRCAALTSKDALAGLDLAGGTKGKGIQ", "length": 330 }, "evidence": [ { "id": "A0A5G2R7L8", "url": "https://omabrowser.org/oma/group/A0A5G2R7L8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7L8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7L8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7L8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7L8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7L8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 17, "end_pos": 19 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7V5-1", "uniprot_ac": "A0A5G2R7V5", "uniprot_id": "A0A5G2R7V5_PIG", "mass": { "chemical_mass": 69557.0, "monoisotopic_mass": 69557.0 }, "refseq": {}, "gene_names": [ { "name": "MPP4", "type": "recommended", "evidence": [ { "id": "A0A5G2R7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5" } ] } ], "protein_names": [ { "name": "MAGUK p55 subfamily member 4", "type": "recommended", "evidence": [ { "id": "A0A5G2R7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5/entry#names_and_taxonomy" } ] }, { "name": "Discs large homolog 6", "type": "synonym", "evidence": [ { "id": "A0A5G2R7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in retinal photoreceptors development.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7V5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5#function" }, { "database": "UniProtKB", "id": "ARBA00055236", "url": "https://www.uniprot.org/uniprotkb/ARBA00055236#function" }, { "database": "UniProtKB", "id": "I3LC30", "url": "https://www.uniprot.org/uniprotkb/I3LC30#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7V5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MPP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5", "locus": { "chromosome": "15", "start_pos": 105277073, "end_pos": 105323578, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026184", "url": "https://www.ensembl.org/id/ENSSSCG00000026184" } ] } } ], "crossref": [ { "id": "A0A5G2R7V5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7V5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026184", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026184", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06799", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06799", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12034", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12034", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PACWIRP", "url": "https://omabrowser.org/oma/group/PACWIRP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23122", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23122", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02828", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02828", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R7V5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFG8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LC30", "url": "https://www.uniprot.org/uniprotkb/I3LC30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LC30-1", "url": "https://www.uniprot.org/uniprotkb/I3LC30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LUP0", "url": "https://www.uniprot.org/uniprotkb/I3LUP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LUP0-1", "url": "https://www.uniprot.org/uniprotkb/I3LUP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIQSDKGADPLSKKDQKDKKLSTATNPESGISQILRLVLQELNLFYSRDVNGVCLLYDLLHCPWLQALLKVYDSLQDFKEKQLIPATPHAQALSNEVLKILCETPKSPEIQELRQILQSPHFKALLSAHDTVAQKDFEPLLPPLPDNIPESEEAMRIVCLVKNQQPLGATIKRHEMTGDILVARVIHGGLVERSGLLYAGDKLVEVNGISVEGLDPEQVIHILAMSRGTIMFKVVPVLDPPVNSHKMVYVRAMTEYWPQEDPAIPCMDAGLPFQKGDILQIVDQNDALWWQARKISDLGTCAGLIPSNHLLKRKQREFWWSQPYQPHNHLKSAICECAATSTQCVPRGEVPCFSTPAAGFRRSMRLCRRKSHLSQLRAKVSGASNCYGAVGAPYEEVVRYQRHPANKHRLIVLVGPSGVGVNELRRQLIELNPNRFQSAVPHTTRSKKSYEMDGREYHYVSKETFESLMYSHRMLEYGEYKGHLYGTSVDAVQAVLDEGKICVMDLEPQGIQVARTQELKPYVIFIKPSSMSCMKRSRKNAKIITDYFVDMKFKEEDLQEMEDLAQKMESQFGQFFDHVIVNDNLQDACAQLLSAVQKAQEEPQWVPATWVSSDN", "length": 615, "header": "tr|A0A5G2R7V5-1|A0A5G2R7V5_PIG Isoform 1 of MAGUK p55 subfamily member 4 OS=Sus scrofa OX=9823 GN=MPP4 PE=1 SV=1 CANONICAL=A0A5G2R7V5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R7V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5/entry#A0A5G2R7V5-1", "sequence": { "sequence": "MIQSDKGADPLSKKDQKDKKLSTATNPESGISQILRLVLQELNLFYSRDVNGVCLLYDLLHCPWLQALLKVYDSLQDFKEKQLIPATPHAQALSNEVLKILCETPKSPEIQELRQILQSPHFKALLSAHDTVAQKDFEPLLPPLPDNIPESEEAMRIVCLVKNQQPLGATIKRHEMTGDILVARVIHGGLVERSGLLYAGDKLVEVNGISVEGLDPEQVIHILAMSRGTIMFKVVPVLDPPVNSHKMVYVRAMTEYWPQEDPAIPCMDAGLPFQKGDILQIVDQNDALWWQARKISDLGTCAGLIPSNHLLKRKQREFWWSQPYQPHNHLKSAICECAATSTQCVPRGEVPCFSTPAAGFRRSMRLCRRKSHLSQLRAKVSGASNCYGAVGAPYEEVVRYQRHPANKHRLIVLVGPSGVGVNELRRQLIELNPNRFQSAVPHTTRSKKSYEMDGREYHYVSKETFESLMYSHRMLEYGEYKGHLYGTSVDAVQAVLDEGKICVMDLEPQGIQVARTQELKPYVIFIKPSSMSCMKRSRKNAKIITDYFVDMKFKEEDLQEMEDLAQKMESQFGQFFDHVIVNDNLQDACAQLLSAVQKAQEEPQWVPATWVSSDN", "length": 615, "header": "tr|A0A5G2R7V5-1|A0A5G2R7V5_PIG Isoform 1 of MAGUK p55 subfamily member 4 OS=Sus scrofa OX=9823 GN=MPP4 PE=1 SV=1 CANONICAL=A0A5G2R7V5-1" }, "locus": { "chromosome": "15", "start_pos": 105318862, "end_pos": 105277676, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090121.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090121.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073160.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073160.1" } ] } }, { "isoform_ac": "A0A8W4FFG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5/entry#A0A8W4FFG8-1", "sequence": { "sequence": "MIQSDKGADPLSKKDQKDKKLSTATNPESGISQILRLVLQELNLFYSRDVNGVCLLYDLLHCPWLQALLKVYDSLQDFKEKQLIPATPHAQALSNEVLKILCETPKSPEIQELRQILQSPHFKGATIKRHEMTGDILVARVIHGGLVERSGLLYAGDKLVEVNGISVEGLDPEQVIHILAMSRGTIMFKVVPVLDPPVNSHKMVYVRAMTEYWPQEDPAIPCMDAGLPFQKGDILQIVDQNDALWWQARKISDLGTCAGLIPSNHLLKRKQREFWWSQPYQPHNHLKSAIYKEEFVGCGQKFYIAGFRRSMRLCRRKSHLSQLRAKVSGASNCYGAVGAPYEEVVRYQRHPANKHRLIVLVGPSGVGVNELRRQLIELNPNRFQSAVPHTTRSKKSYEMDGREYHYVSKETFESLMYSHRMLEYGEYKGHLYGTSVDAVQAVLDEGKICVMDLEPQGIQVARTQELKPYVIFIKPSSMSCMKRSRKNAKIITDYFVDMKFKEEDLQEMEDLAQKMESQFGQFFDHVIVNDNLQDACAQLLSAVQKAQEEPQWVPATWVSSDTESG", "length": 565, "header": "tr|A0A8W4FFG8-1|A0A5G2R7V5_PIG Computationally mapped isoform of MAGUK p55 subfamily member 4 OS=Sus scrofa OX=9823 GN=MPP4 PE=1 SV=1 CANONICAL=A0A5G2R7V5-1" }, "locus": { "chromosome": "15", "start_pos": 105318862, "end_pos": 105277669, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102165.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102165.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077985.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077985.1" } ] } }, { "isoform_ac": "I3LC30-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5/entry#I3LC30-1", "sequence": { "sequence": "MIQSDKGADPLSKKDQKDKKLSTATNPESGISQILRLVLQELNLFYSRDVNGVCLLYDLLHCPWLQALLKVYDSLQDFKEKQLIPATPHAQALSNEVLKILCETPKSPEIQELRQILQSPHFKALLSAHDTVAQKDFEPLLPPLPDNIPESEEAMRIVCLVKNQQPLGATIKRHEMTGDILVARVIHGGLVERSGLLYAGDKLVEVNGISVEGLDPEQVIHILAMSRGTIMFKVVPVLDPPVNSHKMVYVRAMTEYWPQEDPAIPCMDAGLPFQKGDILQIVDQNDALWWQARKISDLGTCAGLIPSNHLLKRKQREFWWSQPYQPHNHLKSAICEYDMKIDEKCVEAGIPCFSTPAAGFRRSMRLCRRKSHLSQLRAKVSGASNCYGAVGAPYEEVVRYQRHPANKHRLIVLVGPSGVGVNELRRQLIELNPNRFQSAVPHTTRSKKSYEMDGREYHYVSKETFESLMYSHRMLEYGEYKGHLYGTSVDAVQAVLDEGKICVMDLEPQGIQVARTQELKPYVIFIKPSSMSCMKRSRKNAKIITDYFVDMKFKEEDLQEMEDLAQKMESQFGQFFDHVIVNDNLQDACAQLLSAVQKAQEEPQWVPATWVSSDN", "length": 615, "header": "tr|I3LC30-1|A0A5G2R7V5_PIG Computationally mapped isoform of MAGUK p55 subfamily member 4 OS=Sus scrofa OX=9823 GN=MPP4 PE=1 SV=2 CANONICAL=A0A5G2R7V5-1" }, "locus": { "chromosome": "15", "start_pos": 105318862, "end_pos": 105277676, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032532.4", "url": "https://www.ensembl.org/id/ENSSSCT00000032532.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021603.2", "url": "https://www.ensembl.org/id/ENSSSCP00000021603.2" } ] } }, { "isoform_ac": "I3LUP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5/entry#I3LUP0-1", "sequence": { "sequence": "MKGKLSEALIYSLRIIPLIRDIDQLGATIKRHEMTGDILVARVIHGGLVERSGLLYAGDKLVEVNGISVEGLDPEQVIHILAMSRGTIMFKVVPVLDPPVNSHKMVYVRAMTEYWPQEDPAIPCMDAGLPFQKGDILQIVDQNDALWWQARKISDLGTCAGLIPSNHLLKRKQREFWWSQPYQPHNHLKSAIYKEEFVGCGQKFYIGTGASNCYGAVGAPYEEVVRYQRHPANKHRLIVLVGPSGVGVNELRRQLIELNPNRFQSAVPHTTRSKKSYEMDGREYHYVSKETFESLMYSHRMLEYGEYKGHLYGTSVDAVQAVLDEGKICVMDLEPQGIQVARTQELKPYVIFIKPSSMSCMKRSRKNAKIITDYFVDMKFKEEDLQEMEDLAQKMESQFGQFFDHVIVNDNLQDACAQLLSAVQKAQEEPQWVPATWVSSDN", "length": 442, "header": "tr|I3LUP0-1|A0A5G2R7V5_PIG Computationally mapped isoform of MAGUK p55 subfamily member 4 OS=Sus scrofa OX=9823 GN=MPP4 PE=1 SV=3 CANONICAL=A0A5G2R7V5-1" }, "locus": { "chromosome": "15", "start_pos": 105309604, "end_pos": 105277676, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030336.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030336.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027840.3", "url": "https://www.ensembl.org/id/ENSSSCP00000027840.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LUP0", "url": "https://www.uniprot.org/uniprotkb/I3LUP0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q6P7F1-1", "protein_name": "MAGUK p55 subfamily member 4", "gene_name": "Mpp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRQSDRGAELTNEDRALPTPPDPENGLSGILRLLLQELSLFYSRDVNGLCLLYDLLHSPWLQALLKVYDCLQRFKEKKLVPDTTHAQILACEVLELLPKASGSPEIQELRQVLQAPHCKALLSAHDTVAQKDFEPLLPPLPDNIPDSEEAMRIVCLVKNQQPLGATIKRHEITGDILVARVIHGGLVERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILAMSCGTIMFKVIPVSAPPVSSQKMVYVRAMIDYWPQEDPDIPCMDAGLPFLKGDILQIVDQNDALWWQARKISDLTICAGLIPSNHLLKRKQREFWWSQPYQPHTCLKSTRALSMEEEDSMKIDEKCVEADEETFESEELAEAKDEFVGDGQKFFIAGFRRSMRLCRRKSHFSQLHASLCCSCSCYSAVGAPYEEVVRYQRQPADKHRLIVLVGPSGVGVNELRRQLIGCNPSCFQSAVPHTTRFPKSYEMDGREYHYVSRETFESLMYGHKMLEYGEYKGHLYGTSVNAVHAVLDEGKICIMDLEPQDIQSARTRDLKPYVIFIKPPNTSSMRHSRKNAKITTDYYVDMKFKDEDLQEMEELAQKMESQFGQFFDHVIVNDNLQDACGQLLSAIQKAQEELQWVPEAWVSPDTES", "length": 635 }, "evidence": [ { "id": "A0A5G2R7V5", "url": "https://omabrowser.org/oma/group/A0A5G2R7V5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JB8-1", "protein_name": "MAGUK p55 subfamily member 4", "gene_name": "MPP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIQSDKGADPPDKKDMKLSTATNPQNGLSQILRLVLQELSLFYGRDVNGVCLLYDLLHSPWLQALLKIYDCLQEFKEKKLVPATPHAQVLSYEVVELLRETPTSPEIQELRQMLQAPHFKALLSAHDTIAQKDFEPLLPPLPDNIPESEEAMRIVCLVKNQQPLGATIKRHEMTGDILVARIIHGGLAERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILAMSRGTIMFKVVPVSDPPVNSQQMVYVRAMTEYWPQEDPDIPCMDAGLPFQKGDILQIVDQNDALWWQARKISDPATCAGLVPSNHLLKRKQREFWWSQPYQPHTCLKSTLSISMEEEDDMKIDEKCVEADEETFESEELSEDKEEFVGYGQKFFIAGFRRSMRLCRRKSHLSPLHASVCCTGSCYSAVGAPYEEVVRYQRRPSDKYRLIVLMGPSGVGVNELRRQLIEFNPSHFQSAVPHTTRTKKSYEMNGREYHYVSKETFENLIYSHRMLEYGEYKGHLYGTSVDAVQTVLVEGKICVMDLEPQDIQGVRTHELKPYVIFIKPSNMRCMKQSRKNAKVITDYYVDMKFKDEDLQEMENLAQRMETQFGQFFDHVIVNDSLHDACAQLLSAIQKAQEEPQWVPATWISSDTESQ", "length": 637 }, "evidence": [ { "id": "A0A5G2R7V5", "url": "https://omabrowser.org/oma/group/A0A5G2R7V5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYH1-1", "protein_name": "MAGUK p55 subfamily member 4", "gene_name": "Mpp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRTVCLVKNQQPLGATIKRHEITGDILVARVIHGGLVERNGLLYAGDKLVEVNGVPVEGLDPEQVIHILAMSCGTIMFKVIPVSAPPVSSQTTVYVRAMIDYWPQEDPDIPCMDAGLPFLKGDILQIVDQSDALWWQARKISDIAICAGLIPSNHLLKRKQREFWWSQPYQPHTCLKSTRSKEEFVGDGQQFFIAGFRQQHANMRCTCSCYSAVGAPYEEVVRYQRQPADKHRLIVLVGPSGVGVNELRRQLIGCNPSCFQSAVPHTTRSPKSYEMDGREYHYVSRETFESLMYGHRMLEFGEYKGHLYGTSVNAVLAVLDEGKICVMDLEPQDIQLARTRELKPYVIFIKPPSMSSMRHSRRNAKIITDYFVDMKFKDEDLQEMEELAQKMESQFGQFFDHVIVNDNLQDARAQLLSAIQKAEEELQWVPEAWVSPGAES", "length": 441 }, "evidence": [ { "id": "A0A5G2R7V5", "url": "https://omabrowser.org/oma/group/A0A5G2R7V5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7V5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7V5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7V5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7V5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7V5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7V5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7V5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 615, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7V5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7V5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5" }, { "id": "PS50052", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50052" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate kinase-like", "eco_id": "ECO_0000259", "start_pos": 408, "end_pos": 597, "start_aa": "His", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5" }, { "id": "PS51022", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L27", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 82, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 157, "end_pos": 238, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7V5" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 245, "end_pos": 315, "start_aa": "His", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7X4-1", "uniprot_ac": "A0A5G2R7X4", "uniprot_id": "A0A5G2R7X4_PIG", "mass": { "chemical_mass": 34632.0, "monoisotopic_mass": 34632.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100522351", "type": "recommended", "evidence": [ { "id": "A0A5G2R7X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R7X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100522351", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4", "locus": {} } ], "crossref": [ { "id": "A0A5G2R7X4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7X4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15419", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15419", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R7X4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHNRNGTLSVVPLQEFVLDGFQGGLQTQALLFALFLALYLAAVLGNLTMIVVITLDARLHSPMYFFLKNLSFLDLCYSSVIYPKALGNILSSAKVISFGGCATQFFFFSLMITTEGFLLAVMAYDHFLAICSPLHYPITMCPSACTRLVLGCYCGGCLNCILQTSFTFSLPFCSSNHIDHFFCDVPPLLLLACADTAINELVLFGICGLIIVGTTLGVLISYAYITVTILRMRSGAGRHKLFSTCGSHMTAVSLFYGTLFVMYAQPGAVESMEQGKVVSVFYTLVIPVLNPLIYSLRNKEVKEALWRLGHKHTAP", "length": 316, "header": "tr|A0A5G2R7X4-1|A0A5G2R7X4_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100522351 PE=3 SV=2 CANONICAL=A0A5G2R7X4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R7X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4/entry#A0A5G2R7X4-1", "sequence": { "sequence": "MSHNRNGTLSVVPLQEFVLDGFQGGLQTQALLFALFLALYLAAVLGNLTMIVVITLDARLHSPMYFFLKNLSFLDLCYSSVIYPKALGNILSSAKVISFGGCATQFFFFSLMITTEGFLLAVMAYDHFLAICSPLHYPITMCPSACTRLVLGCYCGGCLNCILQTSFTFSLPFCSSNHIDHFFCDVPPLLLLACADTAINELVLFGICGLIIVGTTLGVLISYAYITVTILRMRSGAGRHKLFSTCGSHMTAVSLFYGTLFVMYAQPGAVESMEQGKVVSVFYTLVIPVLNPLIYSLRNKEVKEALWRLGHKHTAP", "length": 316, "header": "tr|A0A5G2R7X4-1|A0A5G2R7X4_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100522351 PE=3 SV=2 CANONICAL=A0A5G2R7X4-1" }, "locus": { "chromosome": "15", "start_pos": 139222411, "end_pos": 139213867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071902.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071902.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073180.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073180.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7X4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7X4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 316, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7X4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7X4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7X4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 295, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 47, "end_pos": 49 }, { "start_pos": 6, "end_pos": 8 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7Y5-1", "uniprot_ac": "A0A5G2R7Y5", "uniprot_id": "A0A5G2R7Y5_PIG", "mass": { "chemical_mass": 34888.0, "monoisotopic_mass": 34888.0 }, "refseq": { "ac": "XP_020937964", "name": "olfactory receptor 2B11-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937964" }, "gene_names": [ { "name": "LOC100520315", "type": "recommended", "evidence": [ { "id": "A0A5G2R7Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5" } ] }, { "name": "LOC100520315", "type": "synonym", "evidence": [ { "id": "XP_020937964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937964" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R7Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2B11-like", "type": "synonym", "evidence": [ { "id": "XP_020937964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937964" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100520315", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5", "locus": {} } ], "crossref": [ { "id": "A0A5G2R7Y5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7Y5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100520315", "url": "https://www.ncbi.nlm.nih.gov/gene/100520315", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520315", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520315", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FMIKSSE", "url": "https://omabrowser.org/oma/group/FMIKSSE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R7Y5", "url": "https://www.orthodb.org/?gene=A0A5G2R7Y5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020937964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937964", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R7Y5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILLLTYPMAMVGNIAIILVSTLDSRLHSPMYFFLTNLSFLDMCYTTSIVPQMLFNLGQSKKTISYLGCAIQLYFFHIMGGTESLLLALMSFDRYVAICKPLHYTLIMNRCTCILLVATVWLGGMTYAVSEATVTLHLPLCGHNTLDHLVCEIPVLMKAACGEKGANELTLSVVCIFMLAVPLCFILASYASFGHAVFMIKSSEGRKKAFGTCSSHLIVVFFFYGPAISMYLQPPSSISRDQPKFMALFYGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 312, "header": "tr|A0A5G2R7Y5-1|A0A5G2R7Y5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100520315 PE=3 SV=1 CANONICAL=A0A5G2R7Y5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R7Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5/entry#A0A5G2R7Y5-1", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILLLTYPMAMVGNIAIILVSTLDSRLHSPMYFFLTNLSFLDMCYTTSIVPQMLFNLGQSKKTISYLGCAIQLYFFHIMGGTESLLLALMSFDRYVAICKPLHYTLIMNRCTCILLVATVWLGGMTYAVSEATVTLHLPLCGHNTLDHLVCEIPVLMKAACGEKGANELTLSVVCIFMLAVPLCFILASYASFGHAVFMIKSSEGRKKAFGTCSSHLIVVFFFYGPAISMYLQPPSSISRDQPKFMALFYGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 312, "header": "tr|A0A5G2R7Y5-1|A0A5G2R7Y5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100520315 PE=3 SV=1 CANONICAL=A0A5G2R7Y5-1" }, "locus": { "chromosome": "AEMK02000526.1", "start_pos": 112236, "end_pos": 111301, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089417.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089417.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073195.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073195.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520315", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520315", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7Y5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7Y5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7Y5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "uniprot_ac": "A0A5G2R7Y6", "uniprot_id": "A0A5G2R7Y6_PIG", "mass": { "chemical_mass": 35710.0, "monoisotopic_mass": 35710.0 }, "refseq": { "ac": "XP_003124377", "name": "olfactory receptor 2AE1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124377" }, "gene_names": [ { "name": "LOC100524140", "type": "recommended", "evidence": [ { "id": "A0A5G2R7Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6" } ] }, { "name": "LOC100524140", "type": "synonym", "evidence": [ { "id": "XP_003124377", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124377" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R7Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2AE1-like", "type": "synonym", "evidence": [ { "id": "XP_003124377", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124377" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100524140", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6", "locus": {} } ], "crossref": [ { "id": "A0A5G2R7Y6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7Y6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000051021", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000051021", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524140", "url": "https://www.ncbi.nlm.nih.gov/gene/100524140", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524140", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524140", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R7Y6", "url": "https://www.orthodb.org/?gene=A0A5G2R7Y6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003124377", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124377", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R7Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320, "header": "tr|A0A5G2R7Y6-1|A0A5G2R7Y6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524140 PE=3 SV=1 CANONICAL=A0A5G2R7Y6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R7Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6/entry#A0A5G2R7Y6-1", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320, "header": "tr|A0A5G2R7Y6-1|A0A5G2R7Y6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524140 PE=3 SV=1 CANONICAL=A0A5G2R7Y6-1" }, "locus": { "chromosome": "3", "start_pos": 7714853, "end_pos": 7713894, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075354.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075354.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066721.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066721.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524140", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524140", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "A0A5G2R7Y6", "url": "https://omabrowser.org/oma/group/A0A5G2R7Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7Y6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R7Y6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R7Y6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R7Y6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R7Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Y6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R808-1", "uniprot_ac": "A0A5G2R808", "uniprot_id": "A0A5G2R808_PIG", "mass": { "chemical_mass": 34684.0, "monoisotopic_mass": 34684.0 }, "refseq": { "ac": "XP_013849744", "name": "olfactory receptor 5B12-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849744" }, "gene_names": [ { "name": "LOC100628183", "type": "recommended", "evidence": [ { "id": "A0A5G2R808", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808" } ] }, { "name": "LOC100628183", "type": "synonym", "evidence": [ { "id": "XP_013849744", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849744" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R808", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5B12-like", "type": "synonym", "evidence": [ { "id": "XP_013849744", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849744" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R808", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R808", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100628183", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808", "locus": {} } ], "crossref": [ { "id": "A0A5G2R808", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R808", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100628183", "url": "https://www.ncbi.nlm.nih.gov/gene/100628183", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100628183", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100628183", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGCYVCG", "url": "https://omabrowser.org/oma/group/MGCYVCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R808", "url": "https://www.orthodb.org/?gene=A0A5G2R808", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013849744", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849744", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R808", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R808-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENSTEVTEFLLRGLSNDPELQIPLFIIFSLIYLITAVGNLGMIQLILLDARLHTPMYVLLSHLSLVDLGYSSAVTPKAMMGFLTGDAVISHNACATQFFFFVAFITVESFLLASMAYDRYAAVCTPLHYTTAVTTNVCACLVIGSYVGGFLNASIHTGNIFRLSFCRSNVVDHFFCDAPPLLALSCSDTYVSEMVIFFVVGFNDLFSVLVILVSYLFICITILKMHSSEGRQKAFSTCTSHLTAVSIFYGTGIFMYLQPSSSHSMNTDKVASVFYTMVIPMLNPMVYSLRNKEVKSAFKKAVGRAKSSIRLVF", "length": 314, "header": "tr|A0A5G2R808-1|A0A5G2R808_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100628183 PE=3 SV=1 CANONICAL=A0A5G2R808-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R808-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808/entry#A0A5G2R808-1", "sequence": { "sequence": "MENSTEVTEFLLRGLSNDPELQIPLFIIFSLIYLITAVGNLGMIQLILLDARLHTPMYVLLSHLSLVDLGYSSAVTPKAMMGFLTGDAVISHNACATQFFFFVAFITVESFLLASMAYDRYAAVCTPLHYTTAVTTNVCACLVIGSYVGGFLNASIHTGNIFRLSFCRSNVVDHFFCDAPPLLALSCSDTYVSEMVIFFVVGFNDLFSVLVILVSYLFICITILKMHSSEGRQKAFSTCTSHLTAVSIFYGTGIFMYLQPSSSHSMNTDKVASVFYTMVIPMLNPMVYSLRNKEVKSAFKKAVGRAKSSIRLVF", "length": 314, "header": "tr|A0A5G2R808-1|A0A5G2R808_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100628183 PE=3 SV=1 CANONICAL=A0A5G2R808-1" }, "locus": { "chromosome": "2", "start_pos": 12633916, "end_pos": 12632975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086364.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086364.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072456.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072456.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R808", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100628183", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100628183", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LR31-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100755130", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MENSTEVTKFILAGLTDDPELQVPLFIVFLLIYLSTVLGNLGMIGLILLDSHLHTPMYLFLSHLSLVDFGYSSAVTPKVIAGLLSTDKVISHDACGTQFFFFVGFITTESFLLAVMAYDRYAAVCQPLHYTTTITTNTCACLTISSYVCGFLNSSIHTGNIFRLSFCKFNVIDHFFCDAPPLLALSCSDTSVTEMVIFFVVGFNALFSIVVILISYLFIFVTILRMRSSEGRQKAFSTCASHLTAVSIFYGTVIFMYLQPSSSHTMGTDKMASVFYTMVIPMLNPLVYSLRNKEVKGAFKKAVGNAKSSITLKF", "length": 314 }, "evidence": [ { "id": "A0A5G2R808", "url": "https://omabrowser.org/oma/group/A0A5G2R808/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BH88-1", "protein_name": "Olfactory receptor", "gene_name": "OR5B12C", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MENTTAVTEFLLVGLSDDPQVQILLFITFSLIYLLTLVGNLGMTELILLDSRLHTPMYFFLSQLSLVDFGYSSAVTPKVMAGFLTGDKTISYEACVTQFFFFVAFITVESFLLAAMAYDRYAAVCKPLHYTTAMTTKACARLLVGCYFCGFLNASVHNGNVFRLSFCRANVVNHFFCDAPPLLALSCSDNYVSEMVIFFVVGFNDFFSILVIFISYLFIFITILRMRSSEGRQKAFSTCASHLTAVSIFYGTGIFMYLQPSSSHSMSADKMASVFCAMVIPMLNPLVYSLRNKEVKSAFKTAVGKAKSSIGFVF", "length": 314 }, "evidence": [ { "id": "A0A5G2R808", "url": "https://omabrowser.org/oma/group/A0A5G2R808/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VFX1-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENSTEVTEFILAGLTDDPKLQIPLFIVFLLIYLSTVLGNLGMVGLILLDSHLHTPMYLFLSHLSLVDFGYSSAVTPKVMSGLLSIDKTISHNTCGTQFFFFVGFITTESFLLAAMAYDRYAAVCKPLHYTTTMTTNTCACLTIGSYVCGFLNSSIHTGNIFRLSFCKFNVIDHFFCDAPPLLALSCSDTYISETVIFFVVGFNALFSIVVITISYLLIFITILRMRSSEGRHKAFSTCASHLTAVSIFYGTVIFMYLQPSSSHTMGTDKMASVFYTMVIPMLNPLVYSLRNKEVKGAFKKAVGNAKSALTFLF", "length": 314 }, "evidence": [ { "id": "A0A5G2R808", "url": "https://omabrowser.org/oma/group/A0A5G2R808/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96R08-1", "protein_name": "Olfactory receptor 5B12", "gene_name": "OR5B12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENNTEVTEFILVGLTDDPELQIPLFIVFLFIYLITLVGNLGMIELILLDSCLHTPMYFFLSNLSLVDFGYSSAVTPKVMVGFLTGDKFILYNACATQFFFFVAFITAESFLLASMAYDRYAALCKPLHYTTTMTTNVCACLAIGSYICGFLNASIHTGNTFRLSFCRSNVVEHFFCDAPPLLTLSCSDNYISEMVIFFVVGFNDLFSILVILISYLFIFITIMKMRSPEGRQKAFSTCASHLTAVSIFYGTGIFMYLRPNSSHFMGTDKMASVFYAIVIPMLNPLVYSLRNKEVKSAFKKTVGKAKASIGFIF", "length": 314 }, "evidence": [ { "id": "A0A5G2R808", "url": "https://omabrowser.org/oma/group/A0A5G2R808/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R808", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R808", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R808", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R808", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R808", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R808", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R808-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R808-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R808" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R808", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R808" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R815-1", "uniprot_ac": "A0A5G2R815", "uniprot_id": "A0A5G2R815_PIG", "mass": { "chemical_mass": 31820.0, "monoisotopic_mass": 31820.0 }, "refseq": { "ac": "XP_005657071", "name": "phosphatidylinositol transfer protein alpha isoform isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657071" }, "gene_names": [ { "name": "PITPNA", "type": "recommended", "evidence": [ { "id": "A0A5G2R815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ] }, { "name": "PITPNA", "type": "synonym", "evidence": [ { "id": "XP_005657071", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657071" } ] } ], "protein_names": [ { "name": "Phosphatidylinositol transfer protein alpha isoform", "type": "recommended", "evidence": [ { "id": "A0A5G2R815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815/entry#names_and_taxonomy" } ] }, { "name": "phosphatidylinositol transfer protein alpha isoform isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005657071", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657071" } ] } ], "function": [ { "annotation": "Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions. Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QKM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKM6#function" }, { "database": "UniProtKB", "id": "ARBA00045333", "url": "https://www.uniprot.org/uniprotkb/ARBA00045333#function" }, { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815#function" }, { "database": "UniProtKB", "id": "I3LRS8", "url": "https://www.uniprot.org/uniprotkb/I3LRS8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PITPNA", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815", "locus": { "chromosome": "12", "start_pos": 47739633, "end_pos": 47785375, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000025248", "url": "https://www.ensembl.org/id/ENSSSCG00000025248" } ] } } ], "crossref": [ { "id": "A0A5G2R815", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R815", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000025248", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000025248", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08888", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08888", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100623388", "url": "https://www.ncbi.nlm.nih.gov/gene/100623388", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623388", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623388", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R815", "url": "https://www.orthodb.org/?gene=A0A5G2R815", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10658", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10658", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10658:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10658:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005657071", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657071", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "38571", "url": "https://www.rhea-db.org/rhea/38571", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38691", "url": "https://www.rhea-db.org/rhea/38691", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QKM6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R815-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LRS8", "url": "https://www.uniprot.org/uniprotkb/I3LRS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LRS8-1", "url": "https://www.uniprot.org/uniprotkb/I3LRS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLLKEYRVILPVSVEEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITNEYMKEDFLIKIETWHKPDLGTQENVHKLEPEAWKHVEAVYIDIADRSQVLSKDYKAEEDPAKFKSIKTGRGPLGPNWKQELVNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIHKQERRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQLDEMRQKDPVKGMTADD", "length": 270, "header": "tr|A0A5G2R815-1|A0A5G2R815_PIG Isoform 1 of Phosphatidylinositol transfer protein alpha isoform OS=Sus scrofa OX=9823 GN=PITPNA PE=1 SV=1 CANONICAL=A0A5G2R815-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QKM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815/entry#A0A5G2QKM6-1", "sequence": { "sequence": "MAKERPWSGSGAPCEAGASSRIRGSQSNLSGQFLAPGLCAAIEKILKNETGGGEGVEVLVNEPYEKDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTGECRPEDFLIKIETWHKPDLGTQENVHKLEPEAWKHVEAVYIDIADRSQVLSKDYKAEEDPAKFKSIKTGRGPLGPNWKQELVNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIHKQERRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQLDEVRGLPGAGRGGLGLSAG", "length": 286, "header": "tr|A0A5G2QKM6-1|A0A5G2QKM6_PIG Computationally mapped isoform of Phosphatidylinositol transfer protein alpha isoform OS=Sus scrofa OX=9823 GN=PITPNA PE=1 SV=2 CANONICAL=A0A5G2R815-1" }, "locus": { "chromosome": "12", "start_pos": 47775268, "end_pos": 47756412, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079830.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079830.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065083.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065083.2" } ] } }, { "isoform_ac": "A0A5G2R815-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815/entry#A0A5G2R815-1", "sequence": { "sequence": "MVLLKEYRVILPVSVEEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITNEYMKEDFLIKIETWHKPDLGTQENVHKLEPEAWKHVEAVYIDIADRSQVLSKDYKAEEDPAKFKSIKTGRGPLGPNWKQELVNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIHKQERRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQLDEMRQKDPVKGMTADD", "length": 270, "header": "tr|A0A5G2R815-1|A0A5G2R815_PIG Isoform 1 of Phosphatidylinositol transfer protein alpha isoform OS=Sus scrofa OX=9823 GN=PITPNA PE=1 SV=1 CANONICAL=A0A5G2R815-1" }, "locus": { "chromosome": "12", "start_pos": 47785124, "end_pos": 47743261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083100.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083100.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066751.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066751.1" } ] } }, { "isoform_ac": "I3LRS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815/entry#I3LRS8-1", "sequence": { "sequence": "MVLLKEYRVILPVSVEEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTGECRPEDFLIKIETWHKPDLGTQENVHKLEPEAWKHVEAVYIDIADRSQVLSKDYKAEEDPAKFKSIKTGRGPLGPNWKQELVNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIHKQERRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQLDEVRGLPGAGRGGLGLSAG", "length": 270, "header": "tr|I3LRS8-1|A0A5G2R815_PIG Computationally mapped isoform of Phosphatidylinositol transfer protein alpha isoform OS=Sus scrofa OX=9823 GN=PITPNA PE=1 SV=3 CANONICAL=A0A5G2R815-1" }, "locus": { "chromosome": "12", "start_pos": 47785124, "end_pos": 47756412, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022886.3", "url": "https://www.ensembl.org/id/ENSSSCT00000022886.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026818.3", "url": "https://www.ensembl.org/id/ENSSSCP00000026818.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LRS8", "url": "https://www.uniprot.org/uniprotkb/I3LRS8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623388", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623388", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "phosphatidylcholine binding", "id": "GO:0031210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031210", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "pmid": "" }, { "name": "phosphatidylinositol transfer activity", "id": "GO:0008526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008526", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "pmid": "" }, { "name": "phosphatidylcholine transporter activity", "id": "GO:0008525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "pmid": "" }, { "name": "phospholipid transporter activity", "id": "GO:0005548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005548", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "pmid": "" }, { "name": "phosphatidylcholine transfer activity", "id": "GO:0120019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120019", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "membrane organization", "id": "GO:0061024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061024", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R815", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "38571", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "38571", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38571" } ] }, { "id": "38691", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "38691", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38691" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R815-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 270, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R815-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R815" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R815" }, { "id": "PF02121", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02121" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidylinositol transfer protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 251, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R880-1", "uniprot_ac": "A0A5G2R880", "uniprot_id": "A0A5G2R880_PIG", "mass": { "chemical_mass": 104135.0, "monoisotopic_mass": 104135.0 }, "refseq": { "ac": "XP_013852472", "name": "thrombospondin-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013852472" }, "gene_names": [ { "name": "THBS3", "type": "recommended", "evidence": [ { "id": "A0A5G2R880", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880" } ] }, { "name": "THBS3", "type": "synonym", "evidence": [ { "id": "XP_013852472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013852472" } ] } ], "protein_names": [ { "name": "Thrombospondin-3", "type": "recommended", "evidence": [ { "id": "A0A5G2R880", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880/entry#names_and_taxonomy" } ] }, { "name": "thrombospondin-3", "type": "synonym", "evidence": [ { "id": "XP_013852472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013852472" } ] } ], "function": [ { "annotation": "Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R880", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880#function" }, { "database": "UniProtKB", "id": "ARBA00056051", "url": "https://www.uniprot.org/uniprotkb/ARBA00056051#function" }, { "database": "UniProtKB", "id": "F1RGS0", "url": "https://www.uniprot.org/uniprotkb/F1RGS0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R880", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "THBS3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880", "locus": { "chromosome": "4", "start_pos": 94623902, "end_pos": 94611593, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006524", "url": "https://www.ensembl.org/id/ENSSSCG00000006524" } ] } } ], "crossref": [ { "id": "A0A5G2R880", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R880", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006524", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006524", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16079", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16079", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155108", "url": "https://www.ncbi.nlm.nih.gov/gene/100155108", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024665", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024665", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155108", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155108", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NCPLARN", "url": "https://omabrowser.org/oma/group/NCPLARN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R880", "url": "https://www.orthodb.org/?gene=A0A5G2R880", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10199", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10199", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10199:SF89", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10199:SF89", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-186797", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-186797", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013852472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013852472", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QM67", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QM67-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R880", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R880-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RGS0", "url": "https://www.uniprot.org/uniprotkb/F1RGS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RGS0-1", "url": "https://www.uniprot.org/uniprotkb/F1RGS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METQELRGALALLFLCTFASASQDLQVIDLLTLGESRQMVAVAEKIRTALLTAGDIYLLSTFRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTALLRLRGPSRPSPALQLYVDCKLGDQHAGLPALAPIPPAEVNGLEIRTGQKAYLRMQGFVESMKMILGGSMARVGALSECPFQGDESIHSAVASALHSILGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCTDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTRVSGVGIDYARASKQVCNDIDECNDGDNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSHGCFPARTCHSPAHSPCHVHAHCLFERNGAVSCLCNVGWAGNGNVCGPDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGVPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVPEDFEPFRRQLLQGRV", "length": 956, "header": "tr|A0A5G2R880-1|A0A5G2R880_PIG Isoform 1 of Thrombospondin-3 OS=Sus scrofa OX=9823 GN=THBS3 PE=3 SV=2 CANONICAL=A0A5G2R880-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QM67-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880/entry#A0A5G2QM67-1", "sequence": { "sequence": "METQELRGALALLFLCTFASASQDLQVIDLLTLGESRQMVAVAEKIRTALLTAGDIYLLSTFRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVASALHSILGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCTDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTRVSGVGIDYARASKQVCNDIDECNDGDNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSHGCFPARTCHSPAHSPCHVHAHCLFERNGAVSCLCNVGWAGNGNVCGPDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGVPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVPEDFEPFRRQLLQGRV", "length": 836, "header": "tr|A0A5G2QM67-1|A0A5G2QM67_PIG Computationally mapped isoform of Thrombospondin-3 OS=Sus scrofa OX=9823 GN=THBS3 PE=3 SV=1 CANONICAL=A0A5G2R880-1" }, "locus": { "chromosome": "4", "start_pos": 94623653, "end_pos": 94612766, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086500.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086500.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065125.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065125.1" } ] } }, { "isoform_ac": "A0A5G2R880-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880/entry#A0A5G2R880-1", "sequence": { "sequence": "METQELRGALALLFLCTFASASQDLQVIDLLTLGESRQMVAVAEKIRTALLTAGDIYLLSTFRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTALLRLRGPSRPSPALQLYVDCKLGDQHAGLPALAPIPPAEVNGLEIRTGQKAYLRMQGFVESMKMILGGSMARVGALSECPFQGDESIHSAVASALHSILGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCTDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTRVSGVGIDYARASKQVCNDIDECNDGDNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSHGCFPARTCHSPAHSPCHVHAHCLFERNGAVSCLCNVGWAGNGNVCGPDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGVPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVPEDFEPFRRQLLQGRV", "length": 956, "header": "tr|A0A5G2R880-1|A0A5G2R880_PIG Isoform 1 of Thrombospondin-3 OS=Sus scrofa OX=9823 GN=THBS3 PE=3 SV=2 CANONICAL=A0A5G2R880-1" }, "locus": { "chromosome": "4", "start_pos": 94623653, "end_pos": 94612766, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082327.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082327.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073295.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073295.2" } ] } }, { "isoform_ac": "F1RGS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880/entry#F1RGS0-1", "sequence": { "sequence": "METQELRGALALLFLCTFASASQDLQVIDLLTLGESRQMVAVAEKIRTALLTAGDIYLLSTFRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTALLRLRGPSRPSPALQLYVDCKLGDQHAGLPALAPIPPAEVNGLEIRTGQKAYLRMQGFVESMKMILGGSMARVGALSECPFQGDESIHSAGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCTDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTRVSGVGIDYARASKQVCNDIDECNDGDNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSHGCFPARTCHSPAHSPCHVHAHCLFERNGAVSCLCNVGWAGNGNVCGPDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGVPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVPEDFEPFRRQLLQGRV", "length": 947, "header": "tr|F1RGS0-1|A0A5G2R880_PIG Computationally mapped isoform of Thrombospondin-3 OS=Sus scrofa OX=9823 GN=THBS3 PE=3 SV=3 CANONICAL=A0A5G2R880-1" }, "locus": { "chromosome": "4", "start_pos": 94623653, "end_pos": 94612766, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007145.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007145.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006952.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006952.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RGS0", "url": "https://www.uniprot.org/uniprotkb/F1RGS0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155108", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155108", "resource": "KEGG Pathway" }, { "id": "R-SSC-186797", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-186797", "resource": "Reactome", "description": "Signaling by PDGF" } ], "orthologs": [ { "uniprot_canonical_ac": "P49746-1", "protein_name": "Thrombospondin-3", "gene_name": "THBS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METQELRGALALLLLCFFTSASQDLQVIDLLTVGESRQMVAVAEKIRTALLTAGDIYLLSTFRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTVLLRLRGPSRPSPALHLYVDCKLGDQHAGLPALAPIPPAEVDGLEIRTGQKAYLRMQGFVESMKIILGGSMARVGALSECPFQGDESIHSAVTNALHSILGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFERNGAVSCQCNVGWAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVPEDFEPFRRQLLQGRV", "length": 956 }, "evidence": [ { "id": "A0A5G2R880", "url": "https://omabrowser.org/oma/group/A0A5G2R880/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q05895-1", "protein_name": "Thrombospondin-3", "gene_name": "Thbs3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKPELWGVLALLLLCSYTCGSQDLQVIDLLTVGESRQMVAVAEKIRTALLTAGDIYLLSTFRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTALLRLRGPSRPSPGLQLYVDCKLGDQHAGLPALAPIPPAEVSGLEIRTGQKAYLRMQGFVESMKIILGGSMARVGALSECPFQGDDSIHNAVTSALQSILGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRSHCSPSPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCDDINECAHADPCFPGSSCINTMPGFHCEACPPGYKGTRVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCVPARTCHSPAHSPCHIHAHCLFERNGAVSCQCNVGWAGNGNVCGPDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGVPDYIPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVILDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSISGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWRLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVPEDFEPFRRQLLQGRV", "length": 956 }, "evidence": [ { "id": "A0A5G2R880", "url": "https://omabrowser.org/oma/group/A0A5G2R880/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VM97-1", "protein_name": "Thrombospondin, isoform A", "gene_name": "Tsp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNWTRVLLIGLTALALTFVDVASLSLDPVASAELEQFIRKGDVVISTRHIRPRRKLHISIEALFMIDFPMLKHKMSFFLDRKQQRVTLDISANGATESRNFEIPNINETSTIRSLALQFSKNRITLHVDCKASTHHDIDMNLAKLYTQMDDPVIKLFRERKYPLHFDGDMEHSLQRANCQKGNHRRGNRRMLRNKITEREKNKKRDVRGWYEPTIAREGVVDHRHQEVPTDVERGDIPVLNGDCEDALARSLSDLLALVKLLREDVAHQRQEIAYLRMLLENCAGCKNPLTTDNQLRIEPDCRSANPCYPGVECLDSAAGPRCGHCPLGFIGDGKSCKPGVTCAHHMCYPGVQCHDTVNGAQCDSCPAGYEGDGRTCSLRNPCLDTPCPSGAQCLQVGYPPYFHCISCPMGHEVNGTSCRDMNECLLYDPCDELATCTNLSPGFQCSPCPVGFDGTHAHGYFADYYSVDYRRQTCLDVDECRTGFFRCPEHSTCINEIGSYRCQCHEGYVTNGTYSCLDRSSVFMCPDGTVCDRNAVCLRMDNIRHKCHCNVGWAGNGLICGRDTDVDGWPDQAIGCPELRCQRDNCPKLPNSGQEDADLDGHGDGCDDDADGDNVQNSQDNCWLAYNTEQLDSDGDKVGDVCDNCVLKYNPRQLDTDEDGLGDECDGDIDNDSIPNALDNCPLLPNPSQSDVDNDGVGDACDNCPNLPNPDQKDRDMDFVGDACHRDIDGDDDGVPNSLDNCPMVSNSDQLDTDGDGTGDECDDDMDGDGIPNYKDNCPLAKNPKQDDFNRNGKGDSCEDDEDVDGVPNGMDNCPNNSMIHHTDFRTLQTIPLDPKGLSQADPNWVVHANGTEIVQTLNSDPGLAVGKDAFGGVDFDGTFYINDDTDDDYAGFVFSYQSSYKYYVVQWKKGTQTYWEPRPFTASAAPGIQIKLVNSTEGPGPMMRNSLWHEGNTDGEARLLWKDPKNIAWKERTSYRWSLVHRPAIGLIRLQMHEGNRLIFDSGNVFDSTLKGGRLGVFCFSQRMIIWSNLQYKCNNRVKPLIYNDLSDYLKTKVELQD", "length": 1060 }, "evidence": [ { "id": "A0A5G2R880", "url": "https://omabrowser.org/oma/group/A0A5G2R880/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R880", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R880", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R880", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R880", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R880", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R880", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 937, "end_pos": 939, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R880-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 956, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R880-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R880" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R880", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 316, "end_pos": 354, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R880", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R880" }, { "id": "PS51236", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51236" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TSP C-terminal", "eco_id": "ECO_0000259", "start_pos": 727, "end_pos": 941, "start_aa": "Arg", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 310, "end_pos": 312 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 644, "end_pos": 646 }, { "start_pos": 937, "end_pos": 939 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8D6-1", "uniprot_ac": "A0A5G2R8D6", "uniprot_id": "A0A5G2R8D6_PIG", "mass": { "chemical_mass": 34077.0, "monoisotopic_mass": 34077.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100514947", "type": "recommended", "evidence": [ { "id": "A0A5G2R8D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R8D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100514947", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6", "locus": {} } ], "crossref": [ { "id": "A0A5G2R8D6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8D6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TVASMMY", "url": "https://omabrowser.org/oma/group/TVASMMY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R8D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRNNTSISEFLLMEVTKNPELQTLIFSLFLSMYLVTVLGNLLIILAVSCDSHLHTPMYFFLANLSFTDICLSTTTIPKILVNIHTQNQSITYTGCLTQVCFVLVFASLDSCILSAMAYDRYVAICHPLKYTVIMNSGLCFLLLLLSLFISIVDALLHSLMLLHLSFCTDLEIPLFFCEVVQVIKLACSDTLINNILIYFASSIFGGIPVCGIIFSYAQIVPSVLRMPSAGRKYKAFSTCGSHLSIISLFYGTAFGVYISSAVSNSSKNSTVVSMIYTVVPQMMNPFVYSLRNRDMKGALRKLISI", "length": 307, "header": "tr|A0A5G2R8D6-1|A0A5G2R8D6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100514947 PE=3 SV=1 CANONICAL=A0A5G2R8D6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R8D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6/entry#A0A5G2R8D6-1", "sequence": { "sequence": "MEPRNNTSISEFLLMEVTKNPELQTLIFSLFLSMYLVTVLGNLLIILAVSCDSHLHTPMYFFLANLSFTDICLSTTTIPKILVNIHTQNQSITYTGCLTQVCFVLVFASLDSCILSAMAYDRYVAICHPLKYTVIMNSGLCFLLLLLSLFISIVDALLHSLMLLHLSFCTDLEIPLFFCEVVQVIKLACSDTLINNILIYFASSIFGGIPVCGIIFSYAQIVPSVLRMPSAGRKYKAFSTCGSHLSIISLFYGTAFGVYISSAVSNSSKNSTVVSMIYTVVPQMMNPFVYSLRNRDMKGALRKLISI", "length": 307, "header": "tr|A0A5G2R8D6-1|A0A5G2R8D6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100514947 PE=3 SV=1 CANONICAL=A0A5G2R8D6-1" }, "locus": { "chromosome": "2", "start_pos": 67230481, "end_pos": 67229561, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090994.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090994.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066873.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066873.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4ACI0-1", "protein_name": "Olfactory receptor family 7 subfamily G member 23B", "gene_name": "Or7g23b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELKNQTAVSGFHLLGLTDNHKLLPFIFAMFLSMYLITILGNLLIIMTISSVSQLHTPMYLFLSILSINDICLSTVTIPKMLVNNQAQDKRISYIECLTQICFASIFGDMENFLLAVMAYDCYVAICKPLRYTIIMNPIFCVVMVLLSLLFSITDALLHTLMILRLSFCTELEIPHFVCEMAQIIKLACSDTFLNNLLIFLAVIVFGGGPVCGIAFSYIYIVSSVLRMPSSEGKHRAFSTCASHLSVVSLFYETGFGVYISSAVTDSLRNSAIASVMYTVVPPLLNPFIYSLRNREIKEALRKLFVKLTYLV", "length": 312 }, "evidence": [ { "id": "A0A5G2R8D6", "url": "https://omabrowser.org/oma/group/A0A5G2R8D6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TRG2-1", "protein_name": "Olfactory receptor", "gene_name": "Or7g27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESTNQTDAIEFLLLGLSDDPELQPIIFGLFLFMYLVTFLGNLIITLTISAECHLHTPMYFFLSNLSVADICISSTTVPKMLLNIQTPDHRITYSGCLTQACFVLLFAGLENCLLAAMAYDRYVAICHPLRYTVIMNSCFCSILIVVSLAISAVNALLLSLMVLHLNFCTEVEIPHFFCELAQIIKLACSDTLINNILIYISAFMFGGIPFFGIFLSYTEIVSSVLKIPSRQGRHKAFSTCGSHLSVVSLFYGTGLGVYISSAVTESPRKTAVASVMYSIVTQMLNPFIYSLRNRDMKEALRKHVGRIASIV", "length": 312 }, "evidence": [ { "id": "A0A5G2R8D6", "url": "https://omabrowser.org/oma/group/A0A5G2R8D6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8D6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 307, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8D6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8D6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8D6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 6, "end_pos": 8 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8E5-1", "uniprot_ac": "A0A5G2R8E5", "uniprot_id": "A0A5G2R8E5_PIG", "mass": { "chemical_mass": 35527.0, "monoisotopic_mass": 35527.0 }, "refseq": { "ac": "XP_020919260", "name": "olfactory receptor 2A2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919260" }, "gene_names": [ { "name": "LOC100513612", "type": "synonym", "evidence": [ { "id": "XP_020919260", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919260" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R8E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2A2-like", "type": "synonym", "evidence": [ { "id": "XP_020919260", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919260" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8E5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8E5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5", "locus": {} } ], "crossref": [ { "id": "A0A5G2R8E5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8E5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15420", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15420", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513612", "url": "https://www.ncbi.nlm.nih.gov/gene/100513612", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513612", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513612", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RSMRTVY", "url": "https://omabrowser.org/oma/group/RSMRTVY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R8E5", "url": "https://www.orthodb.org/?gene=A0A5G2R8E5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020919260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919260", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R8E5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGNQSWITEFILVGFQLREEMELLLFVIFFLLYIFNLLANGMILGLICLDLKLHSPMYYFLSHLAVIDMSYPSSSLPNMLENLVKHKKTISFDSCTMQMVFSLAFGSVECLILVVMSYDRYVAICHPLRYTVIMNWKLCIVLAITSWACGFSLALVQVFLLLRLSFCGPQKINHFFCEFRSVLKVACGDTWISEISLFADGVFILVTPISLVLVSYVRILWSVLKIQSKEGRKKAFSTCSSHLCVVGFYFGLAMIVYMVPDNSKQEEQLKILFLFYTLFNPLLNPLVYSLRNAQVKAAFYRVLQINTTV", "length": 310, "header": "tr|A0A5G2R8E5-1|A0A5G2R8E5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R8E5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R8E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5/entry#A0A5G2R8E5-1", "sequence": { "sequence": "MEGNQSWITEFILVGFQLREEMELLLFVIFFLLYIFNLLANGMILGLICLDLKLHSPMYYFLSHLAVIDMSYPSSSLPNMLENLVKHKKTISFDSCTMQMVFSLAFGSVECLILVVMSYDRYVAICHPLRYTVIMNWKLCIVLAITSWACGFSLALVQVFLLLRLSFCGPQKINHFFCEFRSVLKVACGDTWISEISLFADGVFILVTPISLVLVSYVRILWSVLKIQSKEGRKKAFSTCSSHLCVVGFYFGLAMIVYMVPDNSKQEEQLKILFLFYTLFNPLLNPLVYSLRNAQVKAAFYRVLQINTTV", "length": 310, "header": "tr|A0A5G2R8E5-1|A0A5G2R8E5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R8E5-1" }, "locus": { "chromosome": "9", "start_pos": 113546788, "end_pos": 113545859, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073469.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073469.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070392.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070392.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8E5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513612", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513612", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6IF42-1", "protein_name": "Olfactory receptor 2A2", "gene_name": "OR2A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGNQTWITDITLLGFQVGPALAILLCGLFSVFYTLTLLGNGVIFGIICLDSKLHTPMYFFLSHLAIIDMSYASNNVPKMLANLMNQKRTISFVPCIMQTFLYLAFAVTECLILVVMSYDRYVAICHPFQYTVIMSWRVCTILVLTSWSCGFALSLVHEILLLRLPFCGPRDVNHLFCEILSVLKLACADTWVNQVVIFATCVFVLVGPLSLILVSYMHILGAILKIQTKEGRIKAFSTCSSHLCVVGLFFGIAMVVYMVPDSNQREEQEKMLSLFHSVFNPMLNPLIYSLRNAQLKGALHRALQRKRSMRTVYGLCL", "length": 318 }, "evidence": [ { "id": "A0A5G2R8E5", "url": "https://omabrowser.org/oma/group/A0A5G2R8E5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8E5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8E5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8E5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8E5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8E5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8E5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8E5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8E5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 289, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 307, "end_pos": 309 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RCV9-1", "uniprot_ac": "A0A5G2RCV9", "uniprot_id": "A0A5G2RCV9_PIG", "mass": { "chemical_mass": 41401.0, "monoisotopic_mass": 41401.0 }, "refseq": { "ac": "XP_020931391", "name": "tomoregulin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931391" }, "gene_names": [ { "name": "TMEFF2", "type": "recommended", "evidence": [ { "id": "A0A5G2RCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9" } ] }, { "name": "TMEFF2", "type": "synonym", "evidence": [ { "id": "XP_020931391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931391" } ] } ], "protein_names": [ { "name": "Tomoregulin-2", "type": "recommended", "evidence": [ { "id": "A0A5G2RCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein with EGF-like and two follistatin-like domains", "type": "synonym", "evidence": [ { "id": "A0A5G2RCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9/entry#names_and_taxonomy" } ] }, { "name": "tomoregulin-2", "type": "synonym", "evidence": [ { "id": "XP_020931391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931391" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCV9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMEFF2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9", "locus": { "chromosome": "15", "start_pos": 96594970, "end_pos": 96855743, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016064", "url": "https://www.ensembl.org/id/ENSSSCG00000016064" } ] } } ], "crossref": [ { "id": "A0A5G2RCV9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016064", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016064", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "654831", "url": "https://www.ncbi.nlm.nih.gov/gene/654831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:654831", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:654831", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HCQGQTL", "url": "https://omabrowser.org/oma/group/HCQGQTL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RCV9", "url": "https://www.orthodb.org/?gene=A0A5G2RCV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21632:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21632:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020931391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931391", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R8L1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8L1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCV9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SN29", "url": "https://www.uniprot.org/uniprotkb/F1SN29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SN29-1", "url": "https://www.uniprot.org/uniprotkb/F1SN29-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "length": 374, "header": "tr|A0A5G2RCV9-1|A0A5G2RCV9_PIG Isoform 1 of Tomoregulin-2 OS=Sus scrofa OX=9823 GN=TMEFF2 PE=3 SV=2 CANONICAL=A0A5G2RCV9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R8L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9/entry#A0A5G2R8L1-1", "sequence": { "sequence": "MLLKLWRSCAGLAAASPSGATATAAASAAAPRSCVLWKPFAAAELRELVMVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGGRNCHFICLKTYMSILLWIITDVFTITDI", "length": 224, "header": "tr|A0A5G2R8L1-1|A0A5G2RCV9_PIG Computationally mapped isoform of Tomoregulin-2 OS=Sus scrofa OX=9823 GN=TMEFF2 PE=3 SV=2 CANONICAL=A0A5G2RCV9-1" }, "locus": { "chromosome": "15", "start_pos": 96855515, "end_pos": 96839483, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079354.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079354.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073608.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073608.2" } ] } }, { "isoform_ac": "A0A5G2RCV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9/entry#A0A5G2RCV9-1", "sequence": { "sequence": "MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "length": 374, "header": "tr|A0A5G2RCV9-1|A0A5G2RCV9_PIG Isoform 1 of Tomoregulin-2 OS=Sus scrofa OX=9823 GN=TMEFF2 PE=3 SV=2 CANONICAL=A0A5G2RCV9-1" }, "locus": { "chromosome": "15", "start_pos": 96855333, "end_pos": 96595200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082139.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082139.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068509.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068509.2" } ] } }, { "isoform_ac": "F1SN29-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9/entry#F1SN29-1", "sequence": { "sequence": "MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQNNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "length": 353, "header": "tr|F1SN29-1|F1SN29_PIG Computationally mapped isoform of Tomoregulin-2 OS=Sus scrofa OX=9823 GN=TMEFF2 PE=3 SV=4 CANONICAL=A0A5G2RCV9-1" }, "locus": { "chromosome": "15", "start_pos": 96855333, "end_pos": 96595200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017490.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017490.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017018.4", "url": "https://www.ensembl.org/id/ENSSSCP00000017018.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8L1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8L1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:654831", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:654831", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YF05-1", "protein_name": "Tomoregulin-2", "gene_name": "TMEFF2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "ELRAAPSLAGAPSCARRVPAASVRCAGSGAESRGAPPGNGAGLRSAARSVAAAGIGTRVRGGAREGRWGKSYDDRENDLFLCDTNTCKFDGECLRIGDSVTCVCQFKCNNDYVPVCGSNGDTYQNECYLKQAACKQQSEILLVSEGSCATDAGSGSGDGVNEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESARGIYIPCPEHYNGFCMHGKCEHSTNMLEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAIICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "length": 387 }, "evidence": [ { "id": "A0A5G2RCV9", "url": "https://omabrowser.org/oma/group/A0A5G2RCV9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B0S6Y8-1", "protein_name": "Tomoregulin-2a", "gene_name": "tmeff2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVSVAAALHEPRSPHQWSRIVGHWVWIAVLSFLATFPVQQLGAFPSSLSDCQTPTGWNCSGDDDRDTDLFLCDTNTCKFDGECLRIGDIITCICNFKCNNDYVPVCGSNNENYENECFLRRDACKQQTEILVVSEGSCPADAGSGSGDEAGNEGSAENGQKETSTCDICQFGAECDVDAEDVWCVCNIDCSHISFNPVCASDGRSYDNPCQVKEASCQRQERIEVKFLGHCQGDMITGTKAGDGQYARTDYTEEKPEVSEVARGLYIPCPEHYKNYCVHGDCEYPNMLSTPSCSCHSGFSGPQCDTKEYNVLYVVPGSGKLRYVLIASVIGALQVAIICVVVLCITRKCPRTNRINRQKQNTMHYNSENTLRASTRLI", "length": 379 }, "evidence": [ { "id": "A0A5G2RCV9", "url": "https://omabrowser.org/oma/group/A0A5G2RCV9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q17QD6-1", "protein_name": "Tomoregulin-2", "gene_name": "TMEFF2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDFAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "length": 374 }, "evidence": [ { "id": "A0A5G2RCV9", "url": "https://omabrowser.org/oma/group/A0A5G2RCV9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9QYM9-1", "protein_name": "Tomoregulin-2", "gene_name": "Tmeff2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLWESPRQCSSWTLCEGFCWLLLLPVTLLIIARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDTGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "length": 374 }, "evidence": [ { "id": "A0A5G2RCV9", "url": "https://omabrowser.org/oma/group/A0A5G2RCV9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UIK5-1", "protein_name": "Tomoregulin-2", "gene_name": "TMEFF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "length": 374 }, "evidence": [ { "id": "A0A5G2RCV9", "url": "https://omabrowser.org/oma/group/A0A5G2RCV9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCV9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to stress", "id": "GO:0006950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006950", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCV9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RCV9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 374, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RCV9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCV9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 261, "end_pos": 301, "start_aa": "His", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCV9" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 137, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8N0-1", "uniprot_ac": "A0A5G2R8N0", "uniprot_id": "A0A5G2R8N0_PIG", "mass": { "chemical_mass": 29719.0, "monoisotopic_mass": 29719.0 }, "refseq": {}, "gene_names": [ { "name": "ELP6", "type": "recommended", "evidence": [ { "id": "A0A5G2R8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0" } ] } ], "protein_names": [ { "name": "Elongator complex protein 6", "type": "recommended", "evidence": [ { "id": "A0A5G2R8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0/entry#names_and_taxonomy" } ] }, { "name": "Protein TMEM103", "type": "synonym", "evidence": [ { "id": "A0A5G2R8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. Involved in cell migration.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RM73", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM73#function" }, { "database": "UniProtKB", "id": "ARBA00059616", "url": "https://www.uniprot.org/uniprotkb/ARBA00059616#function" }, { "database": "UniProtKB", "id": "A0A5G2R8N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ELP6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0", "locus": { "chromosome": "13", "start_pos": 30325249, "end_pos": 30341295, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011336", "url": "https://www.ensembl.org/id/ENSSSCG00000011336" } ] } } ], "crossref": [ { "id": "A0A5G2R8N0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8N0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011336", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011336", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19495", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19495", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR018627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MFTELNS", "url": "https://omabrowser.org/oma/group/MFTELNS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16184", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16184", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16184:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16184:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09807", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09807", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R8N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RM73", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RM73-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSELSNLLNTSPDKVEQGKLTLLCDVKTDGSFLVHHFLSFYLKAHCKVCFVALTQSFSHYNIVGQKLGVSLTIARERGQLVFLEGLKSAMDIFFRPQEEPHPLQFLREASAGNLQPLYEFVQDALKPVANGEAAWRCPVLLVDDLSVLLSLGVGAVAVLDFIHYCRATVCWEWKGNIVALVHDSGDTEDEENDILLNGLSHQSHLILRAEGLATGFCKDVHGQLSVLWRRPLQPTSQRDQSLTYQYKIQDKNVSFFAKGMSPAVL", "length": 266, "header": "tr|A0A5G2R8N0-1|A0A5G2R8N0_PIG Isoform 1 of Elongator complex protein 6 OS=Sus scrofa OX=9823 GN=ELP6 PE=3 SV=2 CANONICAL=A0A5G2R8N0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R8N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0/entry#A0A5G2R8N0-1", "sequence": { "sequence": "MFSELSNLLNTSPDKVEQGKLTLLCDVKTDGSFLVHHFLSFYLKAHCKVCFVALTQSFSHYNIVGQKLGVSLTIARERGQLVFLEGLKSAMDIFFRPQEEPHPLQFLREASAGNLQPLYEFVQDALKPVANGEAAWRCPVLLVDDLSVLLSLGVGAVAVLDFIHYCRATVCWEWKGNIVALVHDSGDTEDEENDILLNGLSHQSHLILRAEGLATGFCKDVHGQLSVLWRRPLQPTSQRDQSLTYQYKIQDKNVSFFAKGMSPAVL", "length": 266, "header": "tr|A0A5G2R8N0-1|A0A5G2R8N0_PIG Isoform 1 of Elongator complex protein 6 OS=Sus scrofa OX=9823 GN=ELP6 PE=3 SV=2 CANONICAL=A0A5G2R8N0-1" }, "locus": { "chromosome": "13", "start_pos": 30341194, "end_pos": 30330152, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070178.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070178.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072673.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072673.2" } ] } }, { "isoform_ac": "A0A5G2RM73-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0/entry#A0A5G2RM73-1", "sequence": { "sequence": "MFSELSNLLNTSPDKVEQGKLTLLCDVKTDGSFLVHHFLSFYLKAHCKVCFVALTQSFSHYNIVGQKLGVSLTIARERGQLVFLEGLKSAMDIFFRPQEEPHPLQFLREASAGNLQPLYEFVQDALKPVANGEAAWRCPVLLVDDLSVLLSLGVGAVAVLDFIHYCRATVCWEWKGNIVALVHDSGDTEDEENDILLNGLSHQSHLILRAEGLATGFCKDVHGQWTASTTVTQGWWNGAVMVCLCSCGPGIENP", "length": 254, "header": "tr|A0A5G2RM73-1|A0A5G2R8N0_PIG Computationally mapped isoform of Elongator complex protein 6 OS=Sus scrofa OX=9823 GN=ELP6 PE=3 SV=1 CANONICAL=A0A5G2R8N0-1" }, "locus": { "chromosome": "13", "start_pos": 30341194, "end_pos": 30329968, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083811.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083811.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073609.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073609.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RM73", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM73" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QBI1-1", "protein_name": "Elongator complex protein 6", "gene_name": "Elp6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFPELNNLLGTTPDGTEQGKLTLLCDAKTDGSFLVHHFLSFYLKANCKVCFVALVQSFSHYNIVAQKLGVSLTAAREQGQLVFLEGLKSSVDIFFHAQEEPHPLQFLREASAGNLQSLYQFVRDSLKPVDSGETPWKFPVLLVDNLSVLLSLGLEAVAVLDFMQYCRATVCCELKGNVVALVHDNRDAEDKENGILLNGLSHQSHLVLRAEGLATGFCKDVHGQLRILWRRLQPTARRDQSLTYQYKIQDKNVSFFAKGMSPAIL", "length": 265 }, "evidence": [ { "id": "A0A5G2R8N0", "url": "https://omabrowser.org/oma/group/A0A5G2R8N0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B2RYG8-1", "protein_name": "Elongator complex protein 6", "gene_name": "Elp6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFPELNNLLSITPDRTEQGKLTLLCDAKTDGSFLVHHFLSFYLKANCKVCFVALVQSFSHYNIVGQKLGVSLTAARERGQLVFLEGLKSSVEVLFHSQEEPHPLQFLREAGAGNLQSLYTFIQDTLKPADSGESPWKCPVLLVDNLSVLLSLGVGAVAVLDFMQYCRATVCCELKGNVVALVHDTEGAEDEENNILLNGLSHQSHLILRTQGLATGFCKDVHGQLSILWRRSSQPTAQRARSLTYQYKIQDKNVSFFAKGMSRAVL", "length": 266 }, "evidence": [ { "id": "A0A5G2R8N0", "url": "https://omabrowser.org/oma/group/A0A5G2R8N0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0P424-1", "protein_name": "Elongator complex protein 6", "gene_name": "elp6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFPELNSLLNASPDTFKPGDFILLSDRQADASFLIHHYLSFYLRAGCKVCFLGLVQSFSHYSAVGQRLGVSLTQAREKGQLVFLEGLKDSIGAILKEDTSEGTQALSYLRSPRAGLEGLFRFVESSLCQSGDDGPPVLIIDDLSVLLSLGVSAGAILDFTLYCRATVCSELQGNMVILVRCEEEDADDDEEGLNLLQRGLVHQCHLALHVEGLPTGYCRDIHGQMEVWWRQGENDAYNQRKIFQFKVHDKGASFFTRGTSRAVL", "length": 264 }, "evidence": [ { "id": "A0A5G2R8N0", "url": "https://omabrowser.org/oma/group/A0A5G2R8N0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q0PNE2-1", "protein_name": "Elongator complex protein 6", "gene_name": "ELP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFVELNNLLNTTPDRAEQGKLTLLCDAKTDGSFLVHHFLSFYLKANCKVCFVALIQSFSHYSIVGQKLGVSLTMARERGQLVFLEGLKSAVDVVFQAQKEPHPLQFLREANAGNLKPLFEFVREALKPVDSGEARWTYPVLLVDDLSVLLSLGMGAVAVLDFIHYCRATVCWELKGNMVVLVHDSGDAEDEENDILLNGLSHQSHLILRAEGLATGFCRDVHGQLRILWRRPSQPAVHRDQSFTYQYKIQDKSVSFFAKGMSPAVL", "length": 266 }, "evidence": [ { "id": "A0A5G2R8N0", "url": "https://omabrowser.org/oma/group/A0A5G2R8N0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BK75-1", "protein_name": "Elongator complex protein 6", "gene_name": "Elp6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFPELNNLLSTTPDKTEQGTLTLLCDAKTDGSFLVHHFLSFYLKANCKVCFVALVQSFSHYNIVGQKLGVSLTAARDRGQLVFLEGLKSSVEVLFHSQDEPHPLQFLREAGTGNLQSLYTFIQDTLKPADSEESPWKYPVLLVDNLSVLLSLGVGAVAVLDFMQYCRATVCCELKGNVVALVHDTEGATDEGNDTLLNGLSHQSHLILRAEGLATGFCKDVHGQLSILWRRPSRSTAQRAQSLTYQYKIQDKNVSFFAKGMSPAVL", "length": 266 }, "evidence": [ { "id": "A0A5G2R8N0", "url": "https://omabrowser.org/oma/group/A0A5G2R8N0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8L9Y2-1", "protein_name": "Elongator complex protein 6", "gene_name": "ELP6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDRSLNLLDLALGFDEQLAIPSPLNGKVILIEDCVETSGSFVLHQLMKRVLSSNSSDALIFLAFARPFSHYDRILRKLGCNLATHKSNNRLVFFDMLMVKCSDGDQMEDNVSAVAKLFREIQETVRKLQSVTSGNITVMVDDMSLLEIATTGSNSDHVLDFLHYCHTLSSESNCSLVILNHEDIYASMERPAFLLQMVCLADVVIKAEPLASGLANDVHGQLTVLNKGISNSGRGSSRNKLQNFQFRIKENGIDYFYPGCRS", "length": 262 }, "evidence": [ { "id": "A0A5G2R8N0", "url": "https://omabrowser.org/oma/group/A0A5G2R8N0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0" } ], "pmid": "" }, { "name": "elongator holoenzyme complex", "id": "GO:0033588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033588", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0" } ], "pmid": "" }, { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8N0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 266, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8N0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8N0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 253, "end_pos": 255 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8N5-1", "uniprot_ac": "A0A5G2R8N5", "uniprot_id": "A0A5G2R8N5_PIG", "mass": { "chemical_mass": 65201.0, "monoisotopic_mass": 65201.0 }, "refseq": {}, "gene_names": [ { "name": "SPATA18", "type": "recommended", "evidence": [ { "id": "A0A5G2R8N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ] } ], "protein_names": [ { "name": "Mitochondria-eating protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R8N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5/entry#names_and_taxonomy" } ] }, { "name": "Spermatogenesis-associated protein 18", "type": "synonym", "evidence": [ { "id": "A0A5G2R8N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SPATA18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5", "locus": { "chromosome": "8", "start_pos": 39203956, "end_pos": 39163088, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008834", "url": "https://www.ensembl.org/id/ENSSSCG00000008834" } ] } } ], "crossref": [ { "id": "A0A5G2R8N5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8N5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008834", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008834", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR026169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21771:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21771:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SE68", "url": "https://www.uniprot.org/uniprotkb/F1SE68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SE68-1", "url": "https://www.uniprot.org/uniprotkb/F1SE68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADNLRKLVSTESLRSMQDKLENWLREYNNNSCDQNLNYCLELIEQVAKVQGQLFGILTTAAQEGGHYDGVETIKSRLLPWLEASFTAASLGKPVDSKIPSLQDTFDKERQKESVIRDRNIHQLDADLNTTRNQLNQVQDDLAETEKTLEETKNRSAISLLAAEEEINQLRKQLKCLQAQEESRHRPPEHRSSEKRGSERRRVEPRGVDRCGADRCGTAQRKAEEICDYEKQLRTLKDEIAVLSAEKSVLQGRSTRSRSPSPASCSRSRSHSHSRSRSHSHSRSGSHSRSHSRNHSRSRSASPSTAVSRVRSPSPNRAKLSSVARKAALLSRFSDAYSQARLDAQCLLRRCIDKAETVQRIIYIATVEAFHVAKMAFRHFKIRVRKSLTPSYAGSNDFEDAVLDYIICHLDLYDSQSSVNDVIRAMNVNPKISFPPEVDFCLLSNFIQEICCIAFAMQTLDPPLDIAFGADGEIFNDCKYRRSYDSDFTAPLVFYHVWPALMENDCVIMKGEAVTRRGAFWNSVRSVTRCRSRSLSPICPRSRVGLSTPTPQPQQCRIRATSVTYTAAHSNARSLSQ", "length": 577, "header": "tr|A0A5G2R8N5-1|A0A5G2R8N5_PIG Isoform 1 of Mitochondria-eating protein OS=Sus scrofa OX=9823 GN=SPATA18 PE=3 SV=1 CANONICAL=A0A5G2R8N5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R8N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5/entry#A0A5G2R8N5-1", "sequence": { "sequence": "MADNLRKLVSTESLRSMQDKLENWLREYNNNSCDQNLNYCLELIEQVAKVQGQLFGILTTAAQEGGHYDGVETIKSRLLPWLEASFTAASLGKPVDSKIPSLQDTFDKERQKESVIRDRNIHQLDADLNTTRNQLNQVQDDLAETEKTLEETKNRSAISLLAAEEEINQLRKQLKCLQAQEESRHRPPEHRSSEKRGSERRRVEPRGVDRCGADRCGTAQRKAEEICDYEKQLRTLKDEIAVLSAEKSVLQGRSTRSRSPSPASCSRSRSHSHSRSRSHSHSRSGSHSRSHSRNHSRSRSASPSTAVSRVRSPSPNRAKLSSVARKAALLSRFSDAYSQARLDAQCLLRRCIDKAETVQRIIYIATVEAFHVAKMAFRHFKIRVRKSLTPSYAGSNDFEDAVLDYIICHLDLYDSQSSVNDVIRAMNVNPKISFPPEVDFCLLSNFIQEICCIAFAMQTLDPPLDIAFGADGEIFNDCKYRRSYDSDFTAPLVFYHVWPALMENDCVIMKGEAVTRRGAFWNSVRSVTRCRSRSLSPICPRSRVGLSTPTPQPQQCRIRATSVTYTAAHSNARSLSQ", "length": 577, "header": "tr|A0A5G2R8N5-1|A0A5G2R8N5_PIG Isoform 1 of Mitochondria-eating protein OS=Sus scrofa OX=9823 GN=SPATA18 PE=3 SV=1 CANONICAL=A0A5G2R8N5-1" }, "locus": { "chromosome": "8", "start_pos": 39200384, "end_pos": 39163275, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085303.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085303.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072678.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072678.1" } ] } }, { "isoform_ac": "F1SE68-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5/entry#F1SE68-1", "sequence": { "sequence": "MADNLRKLVSTESLRSMQDKLENWLREYNNNSCDQNLNYCLELIEQVAKVQGQLFGILTTAAQEGGHYDGVETIKSRLLPWLEASFTAASLGKPVDSKIPSLQDTFDKERQKESVIRDRNIHQLDADLNTTRNQLNQVQDDLAETEKTLEETKNRSAISLLAAEEEINQLRKQLKCLQAQEESRHRPPEHRSSEKRGSERRRVEPRGVDRCGADRCGTAQRKAEEICDYEKQLRTLKDEIAVLSAEKSVLQGRSTRSRSPSPASCSRSRSHSHSRSRSHSHSRSGSHSRSHSRNHSRSRSASPSTAVSRVRSPSPNRAKLSSVARKAALLSRFSDAYSQARLDAQCLLRRCIDKAETVQRIIYIATVEAFHVAKMAFRHFKIRVRKSLTPSYAGSNDFEDAVLDYIICHLDLYDSQSSVNDVIRAMNVNPKISFPPEVDFCLLSNFIQEICCIAFAMQTLDPPLDIAFGADGEIFNDCKYRRSYDSDFTAPLVFYHVWPALMENDCVIMKGEAVTRRGAFWNSVRSVTRCRSRSLSPICPRSRVGLSTISRSRSPSPIRCGLPRF", "length": 565, "header": "tr|F1SE68-1|F1SE68_PIG Computationally mapped isoform of Mitochondria-eating protein OS=Sus scrofa OX=9823 GN=SPATA18 PE=3 SV=3 CANONICAL=A0A5G2R8N5-1" }, "locus": { "chromosome": "8", "start_pos": 39203785, "end_pos": 39163275, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009670.4", "url": "https://www.ensembl.org/id/ENSSSCT00000009670.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009421.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009421.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of cardiolipin metabolic process", "id": "GO:1900210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900210", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ], "pmid": "" }, { "name": "mitochondrial protein catabolic process", "id": "GO:0035694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035694", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ], "pmid": "" }, { "name": "mitophagy by internal vacuole formation", "id": "GO:0035695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035695", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ], "pmid": "" }, { "name": "cardiolipin binding", "id": "GO:1901612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901612", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8N5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8N5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 577, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8N5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8N5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N5" }, { "id": "PF16026", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mitochondria-eating protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 325, "end_pos": 515, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 154, "end_pos": 156 }, { "start_pos": 294, "end_pos": 296 }, { "start_pos": 30, "end_pos": 32 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8P3-1", "uniprot_ac": "A0A5G2R8P3", "uniprot_id": "A0A5G2R8P3_PIG", "mass": { "chemical_mass": 57548.0, "monoisotopic_mass": 57548.0 }, "refseq": {}, "gene_names": [ { "name": "NECTIN4", "type": "recommended", "evidence": [ { "id": "A0A5G2R8P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" } ] } ], "protein_names": [ { "name": "Nectin-4", "type": "recommended", "evidence": [ { "id": "A0A5G2R8P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3/entry#names_and_taxonomy" } ] }, { "name": "Nectin cell adhesion molecule 4", "type": "synonym", "evidence": [ { "id": "A0A5G2R8P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3/entry#names_and_taxonomy" } ] }, { "name": "Poliovirus receptor-related protein 4", "type": "synonym", "evidence": [ { "id": "A0A5G2R8P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NECTIN4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3", "locus": { "chromosome": "4", "start_pos": 89374358, "end_pos": 89355407, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026861", "url": "https://www.ensembl.org/id/ENSSSCG00000026861" } ] } } ], "crossref": [ { "id": "A0A5G2R8P3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8P3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026861", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026861", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05888", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05888", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07704", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07704", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100154054", "url": "https://www.ncbi.nlm.nih.gov/gene/100154054", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MFYESNG", "url": "https://omabrowser.org/oma/group/MFYESNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8D1G7Y2", "url": "https://www.orthodb.org/?gene=A0A8D1G7Y2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23277:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23277:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-418990", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418990", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-420597", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-420597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R8P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1G7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8D1G7Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1G7Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1G7Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRMFWMDLSYSTCPFPDTNCPQPLPWLPATLPESLHFPLLGLYSAGELETTDLVTVVLGQDAKLPCFYRGDPGEQVEQVAWARVDMSEGARELALLNSKYGLHVSSAYEGRVEQPPPPRNPLDGAVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFTHSRSSAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILQVAFLAEASVRGLEDRKLWQVGREGAMLKCLSEGQPPPSFNWTRLDGPLPSGVRAEGDTLGFPPLTTEHSGTYVCHVSNELSSRDSQVVVDILDPQDTPGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHSDPRNQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLCPGSGRAEEEEDRDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV", "length": 525, "header": "tr|A0A5G2R8P3-1|A0A5G2R8P3_PIG Isoform 1 of Nectin-4 OS=Sus scrofa OX=9823 GN=NECTIN4 PE=3 SV=1 CANONICAL=A0A5G2R8P3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R8P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3/entry#A0A5G2R8P3-1", "sequence": { "sequence": "MKRMFWMDLSYSTCPFPDTNCPQPLPWLPATLPESLHFPLLGLYSAGELETTDLVTVVLGQDAKLPCFYRGDPGEQVEQVAWARVDMSEGARELALLNSKYGLHVSSAYEGRVEQPPPPRNPLDGAVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFTHSRSSAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILQVAFLAEASVRGLEDRKLWQVGREGAMLKCLSEGQPPPSFNWTRLDGPLPSGVRAEGDTLGFPPLTTEHSGTYVCHVSNELSSRDSQVVVDILDPQDTPGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHSDPRNQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLCPGSGRAEEEEDRDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV", "length": 525, "header": "tr|A0A5G2R8P3-1|A0A5G2R8P3_PIG Isoform 1 of Nectin-4 OS=Sus scrofa OX=9823 GN=NECTIN4 PE=3 SV=1 CANONICAL=A0A5G2R8P3-1" }, "locus": { "chromosome": "4", "start_pos": 89372807, "end_pos": 89365827, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076416.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076416.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070493.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070493.1" } ] } }, { "isoform_ac": "A0A8D1G7Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3/entry#A0A8D1G7Y2-1", "sequence": { "sequence": "MPLSLGAEMWGPEAWLLLLLLASFTGLYSAGELETTDLVTVVLGQDAKLPCFYRGDPGEQVEQVAWARVDMSEGARELALLNSKYGLHVSSAYEGRVEQPPPPRNPLDGAVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFTHSRSSAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILQVAFLAEASVRGLEDRKLWQVGREGAMLKCLSEGQPPPSFNWTRLDGPLPSGVRAEGDTLGFPPLTTEHSGTYVCHVSNELSSRDSQVVVDILDPQDTPGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHSDPRNQSEEPEGRSYSTLTTVREIETQTELLCPGSGRAEEEEDRDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV", "length": 484, "header": "tr|A0A8D1G7Y2-1|A0A5G2R8P3_PIG Computationally mapped isoform of Nectin-4 OS=Sus scrofa OX=9823 GN=NECTIN4 PE=3 SV=1 CANONICAL=A0A5G2R8P3-1" }, "locus": { "chromosome": "4", "start_pos": 89372807, "end_pos": 89357243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006978.3", "url": "https://www.ensembl.org/id/ENSSSCT00000006978.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006788.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006788.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1G7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8D1G7Y2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-418990", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418990", "resource": "Reactome", "description": "Adherens junctions interactions" }, { "id": "R-SSC-420597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-420597", "resource": "Reactome", "description": "Nectin/Necl trans heterodimerization" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4ICR1-1", "protein_name": "Nectin-4", "gene_name": "nectin4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSKLLNIGAFLLTFIVCVCSEFMDSPMSLRSFSGSEARLKCVFVAPRDVTVVQVTWSRHTPAGKTQQIITGHYTEGPKVSPEFADGFRFESPDPLTDSTLLIENTVRADEGVYTCSIATFPSGNFQRRISLSVWMYPISSVEHVVLKEGQSYGIAASCRAVAHPPARLSWDTDVSGQSQNRSGDGGVVTTQFSLYPSRSMNGQKLDCLVWHPVYEEPHRLANKLVVQFPPDAEAVGSGSWQIGSSGSEIRCLVKGNPLPQNVSWSRSDGVLPSGVLVQKDRLVFSRPLQQTDEGVYVCRTHNTLGVAKAEFTLQIDAVRSEFSISSSHTLLIVIGAASAGVLVLFVVFAIIYINCNLSRKNRKLKRALSARTEEMISLSRQVSMRRLDSINCDPRAQAEDSSLSRMDSGMKNSVLSVEDRSLLSDVRCRQGDGEFDSLGRPAIYTSYRPERQSKKLREIEEEKNERRRRVESFVRSSNMSLDSGLRDQCSPPASVSSGPTAEANGDGWKRGSRREIHRVERERDRLPEGEEENSALLSETASNYFQCSNSGLVPKTSINGGGTHLRGQVI", "length": 570 }, "evidence": [ { "id": "A0A5G2R8P3", "url": "https://omabrowser.org/oma/group/A0A5G2R8P3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8R007-1", "protein_name": "Nectin-4", "gene_name": "Nectin4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLSLGAEMWGPEAWLRLLFLASFTGQYSAGELETSDVVTVVLGQDAKLPCFYRGDPDEQVGQVAWARVDPNEGIRELALLHSKYGLHVNPAYEDRVEQPPPPRDPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARMRLRVLVPPLPSLNPGPPLEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTQSSRSFTHPRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDRRITHTLQVAFLAEASVRGLEDQNLWQVGREGATLKCLSEGQPPPKYNWTRLDGPLPSGVRVKGDTLGFPPLTTEHSGVYVCHVSNELSSRDSQVTVEVLDPEDPGKQVDLVSASVIIVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHSDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRTEEDDDQDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV", "length": 508 }, "evidence": [ { "id": "A0A5G2R8P3", "url": "https://omabrowser.org/oma/group/A0A5G2R8P3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96NY8-1", "protein_name": "Nectin-4", "gene_name": "NECTIN4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRAEEEEDQDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV", "length": 510 }, "evidence": [ { "id": "A0A5G2R8P3", "url": "https://omabrowser.org/oma/group/A0A5G2R8P3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" } ], "pmid": "" }, { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" } ], "pmid": "" }, { "name": "cell adhesion mediator activity", "id": "GO:0098631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098631", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "symbiont entry into host cell", "id": "GO:0046718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046718", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" } ], "pmid": "" }, { "name": "negative regulation of natural killer cell mediated cytotoxicity", "id": "GO:0045953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045953", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8P3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 525, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8P3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8P3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8P3" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 159, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 296, "end_pos": 298 }, { "start_pos": 445, "end_pos": 447 }, { "start_pos": 504, "end_pos": 506 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8R1-1", "uniprot_ac": "A0A5G2R8R1", "uniprot_id": "A0A5G2R8R1_PIG", "mass": { "chemical_mass": 67456.0, "monoisotopic_mass": 67456.0 }, "refseq": {}, "gene_names": [ { "name": "GBP2", "type": "recommended", "evidence": [ { "id": "A0A5G2R8R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1" } ] } ], "protein_names": [ { "name": "Guanylate binding protein 2, interferon-inducible", "type": "synonym", "evidence": [ { "id": "A0A5G2R8R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8R1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GBP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1", "locus": { "chromosome": "4", "start_pos": 127379740, "end_pos": 127408699, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006923", "url": "https://www.ensembl.org/id/ENSSSCG00000006923" } ] } } ], "crossref": [ { "id": "A0A5G2R8R1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8R1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006923", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006923", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01851", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01851", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QPTCHIL", "url": "https://omabrowser.org/oma/group/QPTCHIL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02263", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02263", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9948001", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9948001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9953170", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9953170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R8R1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4D8", "url": "https://www.uniprot.org/uniprotkb/F1S4D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4D8-1", "url": "https://www.uniprot.org/uniprotkb/F1S4D8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LE01", "url": "https://www.uniprot.org/uniprotkb/I3LE01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LE01-1", "url": "https://www.uniprot.org/uniprotkb/I3LE01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATEILMAGPECLIENINGRLMVNVETAKILSAITQPVVVVVIVGPYRTGKSYLMNKLAGKNKGFSLGSTVQSHTKGIWMWCVPHPRNPDHTLVLDTEGLGDVEKGDNQNDSWLFALAVLLSSTLIYNSVGTINQQAMDQLHYVTELTDCIRAKSSPGTHEVKDSADFVSFFPDFVWTLRDFSLDLQANGEPITPDEYLENSLKLKQGNDKKTKSFNAPRLCIRKFFPEKKCFIFDRPAQRKYLVHLEQLPEEDVDPEFREQVEEFCSYILSHSKVKTLSGGITVNGPRLETLVLTFVNTISSGDLPCMENAVLALAEIENSAAVQKAIAHYEQQMAEKLQLPTETLKELLDLHRASEKEAIDVFMTKSFKDVDQVFQNRLMEQLEAKLDDFCDQNMKASSDYCMTLLQDIFGPLYEDVKQGTFSKPGGFRLFIRKRQELKNKYYQAPRKGIQAEETLKTYLDSREGMDAALLQTDQSLTEKEKEIEVQWMKSESLEAANKISEEMQKKHEQLMQEKEKSFHEHMKQLAEKMEKERAQLLAEQERVLTLKFQEKERLLEQGFKKESLKLLKEMKAIQLRNSESFPMCSIL", "length": 590, "header": "tr|A0A5G2R8R1-1|A0A5G2R8R1_PIG Isoform 1 of Guanylate binding protein 2, interferon-inducible OS=Sus scrofa OX=9823 GN=GBP2 PE=1 SV=1 CANONICAL=A0A5G2R8R1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R8R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1/entry#A0A5G2R8R1-1", "sequence": { "sequence": "MATEILMAGPECLIENINGRLMVNVETAKILSAITQPVVVVVIVGPYRTGKSYLMNKLAGKNKGFSLGSTVQSHTKGIWMWCVPHPRNPDHTLVLDTEGLGDVEKGDNQNDSWLFALAVLLSSTLIYNSVGTINQQAMDQLHYVTELTDCIRAKSSPGTHEVKDSADFVSFFPDFVWTLRDFSLDLQANGEPITPDEYLENSLKLKQGNDKKTKSFNAPRLCIRKFFPEKKCFIFDRPAQRKYLVHLEQLPEEDVDPEFREQVEEFCSYILSHSKVKTLSGGITVNGPRLETLVLTFVNTISSGDLPCMENAVLALAEIENSAAVQKAIAHYEQQMAEKLQLPTETLKELLDLHRASEKEAIDVFMTKSFKDVDQVFQNRLMEQLEAKLDDFCDQNMKASSDYCMTLLQDIFGPLYEDVKQGTFSKPGGFRLFIRKRQELKNKYYQAPRKGIQAEETLKTYLDSREGMDAALLQTDQSLTEKEKEIEVQWMKSESLEAANKISEEMQKKHEQLMQEKEKSFHEHMKQLAEKMEKERAQLLAEQERVLTLKFQEKERLLEQGFKKESLKLLKEMKAIQLRNSESFPMCSIL", "length": 590, "header": "tr|A0A5G2R8R1-1|A0A5G2R8R1_PIG Isoform 1 of Guanylate binding protein 2, interferon-inducible OS=Sus scrofa OX=9823 GN=GBP2 PE=1 SV=1 CANONICAL=A0A5G2R8R1-1" }, "locus": { "chromosome": "4", "start_pos": 127401399, "end_pos": 127387377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069436.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069436.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066998.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066998.1" } ] } }, { "isoform_ac": "F1S4D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1/entry#F1S4D8-1", "sequence": { "sequence": "MNSTRHYHQGCICSTLSYAVRFKVYKFTCGWGKFCTGVEFPELTRGSWVQALSPASESCARSHSSCGFYNDFQGDNQNDSWLFALAVLLSSTLIYNSVGTINQQAMDQLHYVTELTDCIRAKSSPGTHEVKDSADFVSFFPDFVWTLRDFSLDLQANGEPITPDEYLENSLKLKQGNDKKTKSFNAPRLCIRKFFPEKKCFIFDRPAQRKYLVHLEQLPEEDVDPEFREQVEEFCSYILSHSKVKTLSGGITVNGPRECLETLVLTFVNTISSGDLPCMENAVLALAEIENSAAVQKAIAHYEQQMAEKLQLPTETLKELLDLHRASEKEAIDVFMTKSFKDVDQVFQNRLMEQLEAKLDDFCDQNMKASSDYCMTLLQDIFGPLYEDVKQGTFSKPGGFRLFIRKRQELKNKYYQAPRKGIQAEETLKTYLDSREGMDAALLQTDQSLTEKEKEIEVQWMKSESLEAANKISEEMQKKHEQLMQEKEKSFHEHMKQLAEKMEKERAQLLAEQERVLTLKFQVFNCVTSILSPSIVLNQKHCLEVGALCQWKDSSSPNATRHFLLSLLLPLVHSVAEGGLLAG", "length": 583, "header": "tr|F1S4D8-1|A0A5G2R8R1_PIG Computationally mapped isoform of Guanylate binding protein 2, interferon-inducible OS=Sus scrofa OX=9823 GN=GBP2 PE=1 SV=5 CANONICAL=A0A5G2R8R1-1" }, "locus": { "chromosome": "4", "start_pos": 127399925, "end_pos": 127388421, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007583.6", "url": "https://www.ensembl.org/id/ENSSSCT00000007583.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007380.5", "url": "https://www.ensembl.org/id/ENSSSCP00000007380.5" } ] } }, { "isoform_ac": "I3LE01-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1/entry#I3LE01-1", "sequence": { "sequence": "VDSNIFSHLSYVTELTDCIRAKSSPGTHEVKDSADFVSFFPDFVWTLRDFSLDLQANGEPITPDEYLENSLKLKQGNDKKTKSFNAPRLCIRKFFPEKKCFIFDRPAQRKYLVHLEQLPEEDVDPEFREQVEEFCSYILSHSKVKTLSGGITVNGPRECLETLVLTFVNTISSGDLPCMENAVLALAEIENSAAVQKAIAHYEQQMAEKLQLPTETLKELLDLHRASEKEAIDVFMTKSFKDVDQVFQNRLMEQLEAKLDDFCDQNMKASSDYCMTLLQDIFGPLYEDVKQGTFSKPGGFRLFIRKRQELKNKYYQAPRKGIQAEETLKTYLDSREGMDAALLQTDQSLTEKEKEIEVQWMKSESLEAANKISEEMQKKHEQLMQEKEKSFHEHMKQLAEKMEKERAQLLAEQERVLTLKFQEKERLLEQGFKKESLKLLKEMKAIQLRNSESFPMCSIL", "length": 460, "header": "tr|I3LE01-1|A0A5G2R8R1_PIG Computationally mapped isoform of Guanylate binding protein 2, interferon-inducible OS=Sus scrofa OX=9823 GN=GBP2 PE=1 SV=4 CANONICAL=A0A5G2R8R1-1" }, "locus": { "chromosome": "4", "start_pos": 127396803, "end_pos": 127387377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030526.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030526.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022286.4", "url": "https://www.ensembl.org/id/ENSSSCP00000022286.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LE01", "url": "https://www.uniprot.org/uniprotkb/I3LE01" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9948001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9948001", "resource": "Reactome", "description": "CASP4 inflammasome assembly" }, { "id": "R-SSC-9953170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9953170", "resource": "Reactome", "description": "GBP-mediated host defense" } ], "orthologs": [ { "uniprot_canonical_ac": "P32456-1", "protein_name": "Guanylate-binding protein 2", "gene_name": "GBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPEINLPGPMSLIDNTKGQLVVNPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKKNGFSLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDIEKGDNENDSWIFALAILLSSTFVYNSMGTINQQAMDQLHYVTELTDRIKANSSPGNNSVDDSADFVSFFPAFVWTLRDFTLELEVDGEPITADDYLELSLKLRKGTDKKSKSFNDPRLCIRKFFPKRKCFVFDWPAPKKYLAHLEQLKEEELNPDFIEQVAEFCSYILSHSNVKTLSGGIPVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVEKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFMKNSFKDVDQMFQRKLGAQLEARRDDFCKQNSKASSDCCMALLQDIFGPLEEDVKQGTFSKPGGYRLFTQKLQELKNKYYQVPRKGIQAKEVLKKYLESKEDVADALLQTDQSLSEKEKAIEVERIKAESAEAAKKMLEEIQKKNEEMMEQKEKSYQEHVKQLTEKMERDRAQLMAEQEKTLALKLQEQERLLKEGFENESKRLQKDIWDIQMRSKSLEPICNIL", "length": 591 }, "evidence": [ { "id": "A0A5G2R8R1", "url": "https://omabrowser.org/oma/group/A0A5G2R8R1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63663-1", "protein_name": "Guanylate-binding protein 2", "gene_name": "Gbp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASEIHMLQPMCLIENTEAHLVINQEALRILSAINQPVVVVAIVGLYRTGKSYLMNKLAGKRTGFSLGSTVQSHTKGIWMWCVPHPKKAGQTLVLLDTEGLEDVEKGDNQNDCWIFALAVLLSSTFVYNSMGTINQQAMDQLHYVTELTDLIKSKSSPDQSGIDDSANFVGFFPTFVWALRDFSLELEVNGKLVTPDEYLEHSLTLKKGADKKTKSFNEPRLCIRKFFPKRKCFIFDRPALRKQLCKLETLGEEELCSEFVEQVAEFTSYIFSYSAVKTLSGGIIVNGPRLKSLVQTYVGAISSGSLPCMESAVLTLAQIENSAAVQKAITHYEEQMNQKIQMPTETLQELLDLHRLIEREAIEIFLKNSFKDVDQKFQTELGNLLISKRDAFIKKNSDVSSAHCSDLIEDIFGPLEEEVKQGTFSKPGGYFLFLQMRQELEKKYNQAPGKGLEAEAVLKKYFESKEDIVETLLKTDQSLTEAAKEIEVERIKAETAEAANRELAEKQEKFELMMQQKEESYQEHVRQLTEKMKEEQKKLIEEQDNIIALKLREQEKFLREGYENESKKLLREIENMKRRQSPGKCTIL", "length": 589 }, "evidence": [ { "id": "A0A5G2R8R1", "url": "https://omabrowser.org/oma/group/A0A5G2R8R1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Z0E6-1", "protein_name": "Guanylate-binding protein 2", "gene_name": "Gbp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASEIHMSEPMCLIENTEAQLVINQEALRILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKRTGFSLGSTVQSHTKGIWMWCVPHPKKAGQTLVLLDTEGLEDVEKGDNQNDCWIFALAVLLSSTFIYNSIGTINQQAMDQLHYVTELTDLIKSKSSPDQSGVDDSANFVGFFPTFVWTLRDFSLELEVNGKPVTSDEYLEHSLTLKKGADKKTKSFNEPRLCIRKFFPKRKCFIFDRPAQRKQLSKLETLREEELCGEFVEQVAEFTSYILSYSSVKTLCGGIIVNGPRLKSLVQTYVGAISNGSLPCMESAVLTLAQIENSAAVQKAITHYEEQMNQKIQMPTETLQELLDLHRPIESEAIEVFLKNSFKDVDQKFQTELGNLLVAKRDAFIKKNMDVSSARCSDLLEDIFGPLEEEVKLGTFSKPGGYYLFLQMRQELEKKYNQAPGKGLQAEAMLKNYFDSKADVVETLLQTDQSLTEAAKEVEEERTKAEAAEAANRELEKKQKEFELMMQQKEKSYQEHVKKLTEKMKDEQKQLLAEQENIIAAKLREQEKFLKEGFENESKKLIREIDTLKQNKSSGKCTIL", "length": 589 }, "evidence": [ { "id": "A0A5G2R8R1", "url": "https://omabrowser.org/oma/group/A0A5G2R8R1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8R1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8R1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8R1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1" } ], "pmid": "" }, { "name": "cellular response to type II interferon", "id": "GO:0071346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071346", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8R1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1" } ], "pmid": "" }, { "name": "defense response to protozoan", "id": "GO:0042832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042832", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8R1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8R1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8R1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8R1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 590, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8R1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8R1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R1" }, { "id": "PS51715", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51715" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GB1/RHD3-type G", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 275, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8R4-1", "uniprot_ac": "A0A5G2R8R4", "uniprot_id": "A0A5G2R8R4_PIG", "mass": { "chemical_mass": 44467.0, "monoisotopic_mass": 44467.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100524300", "type": "recommended", "evidence": [ { "id": "A0A5G2R8R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R4" } ] } ], "protein_names": [ { "name": "Peptidase A1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R8R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8R4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100524300", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R4", "locus": {} } ], "crossref": [ { "id": "A0A5G2R8R4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8R4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013098", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013098", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47966:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47966:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R8R4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RIC8", "url": "https://www.uniprot.org/uniprotkb/F1RIC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RIC8-1", "url": "https://www.uniprot.org/uniprotkb/F1RIC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSCWLSLICFLFPMHRERIPLMKVKSIRENLREKGLLENFLEEHPYDMIQNQGSQNSTFKRKVIRHRLRNYFDMIYVGNITVGTPPQQFSVVFDTGSTDLWVPSVYCHSMACVTHNIFDPFQSSTFRFSATPIRLEYGSGMVSGFLGYDTVRIGRLIIMGQGFCITSWEESKTFEHAPFDGMLGLGYASLGIRGVTPVFDNIKRRGFLDQPVFAFYLSTKSEQGSVVIFGGVDHRYYRGDLRWVPLSKPHYWQIALDRISWRGYVIACKAGCQAIVDTGTSLLRGPNADVRNIQKLIGAHYFHREYVIRCSAPDTLPDIVFTINNVQYPVPARAYIRKNTNGICLSNFKGLIGHFNREAIWILGDVFLRLYFTVFDRGQNRIGLATAV", "length": 389, "header": "tr|A0A5G2R8R4-1|A0A5G2R8R4_PIG Isoform 1 of Peptidase A1 domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100524300 PE=3 SV=2 CANONICAL=A0A5G2R8R4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R8R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R4/entry#A0A5G2R8R4-1", "sequence": { "sequence": "MDSCWLSLICFLFPMHRERIPLMKVKSIRENLREKGLLENFLEEHPYDMIQNQGSQNSTFKRKVIRHRLRNYFDMIYVGNITVGTPPQQFSVVFDTGSTDLWVPSVYCHSMACVTHNIFDPFQSSTFRFSATPIRLEYGSGMVSGFLGYDTVRIGRLIIMGQGFCITSWEESKTFEHAPFDGMLGLGYASLGIRGVTPVFDNIKRRGFLDQPVFAFYLSTKSEQGSVVIFGGVDHRYYRGDLRWVPLSKPHYWQIALDRISWRGYVIACKAGCQAIVDTGTSLLRGPNADVRNIQKLIGAHYFHREYVIRCSAPDTLPDIVFTINNVQYPVPARAYIRKNTNGICLSNFKGLIGHFNREAIWILGDVFLRLYFTVFDRGQNRIGLATAV", "length": 389, "header": "tr|A0A5G2R8R4-1|A0A5G2R8R4_PIG Isoform 1 of Peptidase A1 domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100524300 PE=3 SV=2 CANONICAL=A0A5G2R8R4-1" }, "locus": { "chromosome": "2", "start_pos": 10599658, "end_pos": 10593204, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090979.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090979.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072708.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072708.2" } ] } }, { "isoform_ac": "F1RIC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R4/entry#F1RIC8-1", "sequence": { "sequence": "RVWVIVFHLLKMIELRIPLMKVKSIRENLREKGLLENFLEEHPYDMIQNQGSQNSTFKRKVIRHRLRNYFDMIYVGNITVGTPPQQFSVVFDTGSTDLWVPSVYCHSMACVTHNIFDPFQSSTFRFSATPIRLEYGSGMVSGFLGYDTVRIGRLIIMGQGFCITSWEESKTFEHAPFDGMLGLGYASLGIRGVTPVFDNIKRRGFLDQPVFAFYLSTKSEQGSVVIFGGVDHRYYRGDLRWVPLSKPHYWQIALDRISWRGYVIACKAGCQAIVDTGTSLLRGPNADVRNIQKLIGAHYFHREYVIRCSAPDTLPDIVFTINNVQYPVPARAYIRKNTNGICLSNFKGLIGHFNREAIWILGDVFLRLYFTVFDRGQNRIGLATAV", "length": 386, "header": "tr|F1RIC8-1|A0A5G2R8R4_PIG Computationally mapped isoform of Peptidase A1 domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100524300 PE=3 SV=2 CANONICAL=A0A5G2R8R4-1" }, "locus": { "chromosome": "2", "start_pos": 10599860, "end_pos": 10593204, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014318.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014318.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013932.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013932.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RIC8", "url": "https://www.uniprot.org/uniprotkb/F1RIC8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8R4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8R4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8R4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8R4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 389, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8R4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8R4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8R4" }, { "id": "PS51767", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51767" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase A1", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 386, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 57, "end_pos": 59 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8X1-1", "uniprot_ac": "A0A5G2R8X1", "uniprot_id": "A0A5G2R8X1_PIG", "mass": { "chemical_mass": 34961.0, "monoisotopic_mass": 34961.0 }, "refseq": { "ac": "XP_013849275", "name": "olfactory receptor 1J4-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849275" }, "gene_names": [ { "name": "LOC100520823", "type": "recommended", "evidence": [ { "id": "A0A5G2R8X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1" } ] }, { "name": "LOC100520823", "type": "synonym", "evidence": [ { "id": "XP_013849275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849275" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R8X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1J4-like", "type": "synonym", "evidence": [ { "id": "XP_013849275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849275" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8X1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8X1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100520823", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1", "locus": {} } ], "crossref": [ { "id": "A0A5G2R8X1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8X1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100520823", "url": "https://www.ncbi.nlm.nih.gov/gene/100520823", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520823", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520823", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R8X1", "url": "https://www.orthodb.org/?gene=A0A5G2R8X1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013849275", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849275", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R8X1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRENQSHVSEFLLLGLPIWPEQQGVFFVLFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTLDQSIPYAECVTQMYFFLFFSGLDDFLLTSMAYDRYVAICHPLHYTTIMREGLCSLLVSVSWIFSLANALCHTLLLAQLSFCADYTIPHFFCDLGALLKLSCSDTSLNELVIFTVGLAVITLPLMCILVSYGHIGATILKVPSTKGICKALSTCGSHLSVVSLYYGTIIGLYFVPSSSTSSDKDIVASVMYTVVTPLLNPFIYSLRNRDMKRALEKLFKKPSVLC", "length": 312, "header": "tr|A0A5G2R8X1-1|A0A5G2R8X1_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100520823 PE=3 SV=1 CANONICAL=A0A5G2R8X1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R8X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1/entry#A0A5G2R8X1-1", "sequence": { "sequence": "MRRENQSHVSEFLLLGLPIWPEQQGVFFVLFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTLDQSIPYAECVTQMYFFLFFSGLDDFLLTSMAYDRYVAICHPLHYTTIMREGLCSLLVSVSWIFSLANALCHTLLLAQLSFCADYTIPHFFCDLGALLKLSCSDTSLNELVIFTVGLAVITLPLMCILVSYGHIGATILKVPSTKGICKALSTCGSHLSVVSLYYGTIIGLYFVPSSSTSSDKDIVASVMYTVVTPLLNPFIYSLRNRDMKRALEKLFKKPSVLC", "length": 312, "header": "tr|A0A5G2R8X1-1|A0A5G2R8X1_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100520823 PE=3 SV=1 CANONICAL=A0A5G2R8X1-1" }, "locus": { "chromosome": "1", "start_pos": 263047224, "end_pos": 263046289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075661.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075661.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073723.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073723.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8X1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520823", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520823", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8X1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8X1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8X1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8X1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8X1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8X1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8X1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8X1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R907-1", "uniprot_ac": "A0A5G2R907", "uniprot_id": "A0A5G2R907_PIG", "mass": { "chemical_mass": 74812.0, "monoisotopic_mass": 74812.0 }, "refseq": {}, "gene_names": [ { "name": "GLB1L3", "type": "recommended", "evidence": [ { "id": "A0A5G2R907", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907" } ] } ], "protein_names": [ { "name": "Beta-galactosidase", "type": "recommended", "evidence": [ { "id": "A0A5G2R907", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.23", "type": "synonym", "evidence": [ { "id": "A0A5G2R907", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R907", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GLB1L3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907", "locus": { "chromosome": "9", "start_pos": 60940093, "end_pos": 60918345, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000056489", "url": "https://www.ensembl.org/id/ENSSSCG00000056489" } ] } } ], "crossref": [ { "id": "A0A5G2R907", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R907", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015258", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015258", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23421", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23421", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01301", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01301", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2022857", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022857", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2024101", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2024101", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9840310", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R907", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R907-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSPPRFSPWVSWRRILCIVSLPFISSGFAPRMKNRQNFIFEKVQPSQHRYNWSHLTPLELQDRSVGLQTEQRAGRNPYFTLEGHEFLILGGSIHYFRVPRESWRDRLLKLKACGFNTVTTYVPWNLHEPERGKFDFSGNLDMEAFILLAAEVGLWVILRPGPYICSEIDLGGLPSRLLQDPTSQLRTTNHSFIEAVDEYLDHLIARVVPLQYRKGGPIIAVQVENEYGSFHKDEAYMPYLHKALLKRGIVELLLTSDNTNEVLKGHIKGVLATVNMKSFKEGEFKDLYQVQSNKPILIMEFWVGWFDTWGNKHAVRDAIDVENTIFDFIRLEISFNVYMFHGGTNFGFMNGATYFEQHRGVVTSYDYDAVLTEAGDYTPKFFKLRELFKSIFVTPLPALPEPTPKAVYPLVRPSLYLPLWDALQYLNSPVLSNVPLNMENLPINNGNGQSYGLVLYQTTICSGGQLHANAQDMAQVFLNETNLGTLANGRQDVYIPRITECQLLRILVENQGRVNFSWKIQNQQKGLIGPVTINDIPLESFTIYSLELKMSFFKRLRSASWKPVPDGHLGHPAFYLGTLKAGSSPMDTFLTLPDWNYGFVFINGRNLGRYWNIGPQKTLYLPGSWLQPEDNEIILFEKIMSGSYIHTTDKPIL", "length": 654, "header": "tr|A0A5G2R907-1|A0A5G2R907_PIG Isoform 1 of Beta-galactosidase OS=Sus scrofa OX=9823 GN=GLB1L3 PE=3 SV=2 CANONICAL=A0A5G2R907-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R907-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907/entry#A0A5G2R907-1", "sequence": { "sequence": "MGSPPRFSPWVSWRRILCIVSLPFISSGFAPRMKNRQNFIFEKVQPSQHRYNWSHLTPLELQDRSVGLQTEQRAGRNPYFTLEGHEFLILGGSIHYFRVPRESWRDRLLKLKACGFNTVTTYVPWNLHEPERGKFDFSGNLDMEAFILLAAEVGLWVILRPGPYICSEIDLGGLPSRLLQDPTSQLRTTNHSFIEAVDEYLDHLIARVVPLQYRKGGPIIAVQVENEYGSFHKDEAYMPYLHKALLKRGIVELLLTSDNTNEVLKGHIKGVLATVNMKSFKEGEFKDLYQVQSNKPILIMEFWVGWFDTWGNKHAVRDAIDVENTIFDFIRLEISFNVYMFHGGTNFGFMNGATYFEQHRGVVTSYDYDAVLTEAGDYTPKFFKLRELFKSIFVTPLPALPEPTPKAVYPLVRPSLYLPLWDALQYLNSPVLSNVPLNMENLPINNGNGQSYGLVLYQTTICSGGQLHANAQDMAQVFLNETNLGTLANGRQDVYIPRITECQLLRILVENQGRVNFSWKIQNQQKGLIGPVTINDIPLESFTIYSLELKMSFFKRLRSASWKPVPDGHLGHPAFYLGTLKAGSSPMDTFLTLPDWNYGFVFINGRNLGRYWNIGPQKTLYLPGSWLQPEDNEIILFEKIMSGSYIHTTDKPIL", "length": 654, "header": "tr|A0A5G2R907-1|A0A5G2R907_PIG Isoform 1 of Beta-galactosidase OS=Sus scrofa OX=9823 GN=GLB1L3 PE=3 SV=2 CANONICAL=A0A5G2R907-1" }, "locus": { "chromosome": "9", "start_pos": 60940053, "end_pos": 60918681, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073336.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073336.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070603.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070603.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R907", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2022857", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022857", "resource": "Reactome", "description": "Keratan sulfate degradation" }, { "id": "R-SSC-2024101", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2024101", "resource": "Reactome", "description": "CS/DS degradation" }, { "id": "R-SSC-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "beta-galactosidase activity", "id": "GO:0004565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004565", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R907", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R907", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "galactose catabolic process", "id": "GO:0019388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019388", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R907", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 516, "end_pos": 518, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-1605624", "name": "Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal membrane, lysosomal lumen", "input_participant_list": [ "R-ALL-1605715" ], "output_participant_list": [ "R-ALL-1605637" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1605624", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1605624" } ] }, { "id": "R-SSC-1606312", "name": "GLB1 hydrolyzes SapB/C:LacCer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1606312", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1606312" } ] }, { "id": "R-SSC-1630306", "name": "GLB1 hydrolyses a glycosaminoglycan", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2104997" ], "output_participant_list": [ "R-ALL-2104995" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1630306", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1630306" } ] }, { "id": "R-SSC-2090079", "name": "GLB1 hydrolyses linker chain(2)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2090075" ], "output_participant_list": [ "R-ALL-2090063" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2090079", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2090079" } ] }, { "id": "R-SSC-9840795", "name": "Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9840795", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840795" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1605637", "participant_name": "Gal [lysosomal lumen]", "crossref": [ { "id": "ZINC000000901155", "database": "ZINC", "url": "" }, { "id": "C00984", "database": "COMPOUND", "url": "" }, { "id": "HMDB0000143", "database": "HMDB Metabolite", "url": "" }, { "id": "4646", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "28061", "database": "ChEBI", "url": "" }, { "id": "G09546QO", "database": "GlyTouCan", "url": "" } ] }, { "participant_id": "R-ALL-1605715", "participant_name": "H2O [lysosomal lumen]", "crossref": [ { "id": "15377", "database": "ChEBI", "url": "" }, { "id": "8145132", "database": "PubChem Substance", "url": "" }, { "id": "C00001", "database": "COMPOUND", "url": "" }, { "id": "HMDB0002111", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-2090063", "participant_name": "D-xylose [lysosomal lumen]", "crossref": [ { "id": "C00181", "database": "COMPOUND", "url": "" }, { "id": "ZINC000018168715", "database": "ZINC", "url": "" }, { "id": "4724", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "15936", "database": "ChEBI", "url": "" }, { "id": "G01550VL", "database": "GlyTouCan", "url": "" } ] }, { "participant_id": "R-ALL-2090075", "participant_name": "linker chain(2) [lysosomal lumen]", "crossref": [ { "id": "154964", "database": "ChEBI", "url": "" }, { "id": "G87877ES", "database": "GlyTouCan", "url": "" } ] }, { "participant_id": "R-ALL-2104995", "participant_name": "GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]", "crossref": [ { "id": "ZINC000096085297", "database": "ZINC", "url": "" }, { "id": "63851", "database": "ChEBI", "url": "" }, { "id": "G80016QC", "database": "GlyTouCan", "url": "" }, { "id": "G06780", "database": "KEGG Glycan", "url": "" }, { "id": "ZINC000096085298", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2104997", "participant_name": "Gal-GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]", "crossref": [ { "id": "63850", "database": "ChEBI", "url": "" }, { "id": "G13032", "database": "KEGG Glycan", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R907-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 654, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R907-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R907" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R907", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907" }, { "id": "PF21317", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21317" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-galactosidase 1-like first all-beta", "eco_id": "ECO_0000259", "start_pos": 449, "end_pos": 548, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R907", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907" }, { "id": "PF21467", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21467" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-galactosidase galactose-binding", "eco_id": "ECO_0000259", "start_pos": 573, "end_pos": 632, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R907", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R907" }, { "id": "PF01301", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01301" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycoside hydrolase 35 catalytic", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 391, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 516, "end_pos": 518 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R936-1", "uniprot_ac": "A0A5G2R936", "uniprot_id": "A0A5G2R936_PIG", "mass": { "chemical_mass": 46243.0, "monoisotopic_mass": 46243.0 }, "refseq": {}, "gene_names": [ { "name": "AMDHD1", "type": "recommended", "evidence": [ { "id": "A0A5G2R936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936" } ] } ], "protein_names": [ { "name": "Probable imidazolonepropionase", "type": "recommended", "evidence": [ { "id": "A0A5G2R936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936/entry#names_and_taxonomy" } ] }, { "name": "3.5.2.7", "type": "synonym", "evidence": [ { "id": "A0A5G2R936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936/entry#names_and_taxonomy" } ] }, { "name": "Amidohydrolase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A5G2R936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R936", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AMDHD1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936", "locus": { "chromosome": "5", "start_pos": 87551913, "end_pos": 87569305, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000893", "url": "https://www.ensembl.org/id/ENSSSCG00000000893" } ] } } ], "crossref": [ { "id": "A0A5G2R936", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R936", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000893", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000893", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01296", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01296", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR42752", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42752", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42752:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42752:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-70921", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70921", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "23660", "url": "https://www.rhea-db.org/rhea/23660", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R936", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R936-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGHRLLLENARQVVAVCARGERFLARDALHRLVVLEGASLVVGTDGFLKAIGPADAIRELFAEDTFEERIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMEIHQAGGGINFTERTRQASEEELFRSLQQRLGCMMRAGSTLVECKSGYGLSLETELKMLRVIERARRELDIVSATYCGAHAVPKGKTAPEAADDIIHSHPKLQELGRNGEIRVDNIDVFCEKGVFDLEATRRILQSGKDAGLQINFHGDELHPMKAAELGAELGAQAVSHLEEVSDEGIDAMATARCAAILLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMPEALAAATINAAYALGRSHTHGSLEIGKQGDLIIINSRWEHLIQFGGHHELIEYVIVKGKVVYKKQ", "length": 422, "header": "tr|A0A5G2R936-1|A0A5G2R936_PIG Isoform 1 of Probable imidazolonepropionase OS=Sus scrofa OX=9823 GN=AMDHD1 PE=1 SV=2 CANONICAL=A0A5G2R936-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R936-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936/entry#A0A5G2R936-1", "sequence": { "sequence": "MAGGHRLLLENARQVVAVCARGERFLARDALHRLVVLEGASLVVGTDGFLKAIGPADAIRELFAEDTFEERIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMEIHQAGGGINFTERTRQASEEELFRSLQQRLGCMMRAGSTLVECKSGYGLSLETELKMLRVIERARRELDIVSATYCGAHAVPKGKTAPEAADDIIHSHPKLQELGRNGEIRVDNIDVFCEKGVFDLEATRRILQSGKDAGLQINFHGDELHPMKAAELGAELGAQAVSHLEEVSDEGIDAMATARCAAILLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMPEALAAATINAAYALGRSHTHGSLEIGKQGDLIIINSRWEHLIQFGGHHELIEYVIVKGKVVYKKQ", "length": 422, "header": "tr|A0A5G2R936-1|A0A5G2R936_PIG Isoform 1 of Probable imidazolonepropionase OS=Sus scrofa OX=9823 GN=AMDHD1 PE=1 SV=2 CANONICAL=A0A5G2R936-1" }, "locus": { "chromosome": "5", "start_pos": 87569246, "end_pos": 87553025, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072367.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072367.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073793.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073793.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R936", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-70921", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70921", "resource": "Reactome", "description": "Histidine catabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R936", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R936", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936" } ], "pmid": "" }, { "name": "imidazolonepropionase activity", "id": "GO:0050480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050480", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R936", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "L-histidine catabolic process to glutamate and formamide", "id": "GO:0019556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019556", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R936", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936" } ], "pmid": "" }, { "name": "L-histidine catabolic process", "id": "GO:0006548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006548", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R936", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23660", "name": "", "equation": "4-imidazolone-5-propanoate + H2O = N-formimidoyl-L-glutamate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "23660", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23660" } ] }, { "id": "R-SSC-70906", "name": "4-imidazolone-5-propanoate + H2O => N-formiminoglutamate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-70906", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70906" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R936-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 422, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R936-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R936" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R936" }, { "id": "PF07969", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07969" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amidohydrolase 3", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 419, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R979-1", "uniprot_ac": "A0A5G2R979", "uniprot_id": "A0A5G2R979_PIG", "mass": { "chemical_mass": 35354.0, "monoisotopic_mass": 35354.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100515706", "type": "recommended", "evidence": [ { "id": "A0A5G2R979", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R979", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R979", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R979", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100515706", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979", "locus": {} } ], "crossref": [ { "id": "A0A5G2R979", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R979", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515706", "url": "https://www.ncbi.nlm.nih.gov/gene/100515706", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515706", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515706", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ssc:110255199", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255199", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FMTLPMD", "url": "https://omabrowser.org/oma/group/FMTLPMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R979", "url": "https://www.orthodb.org/?gene=A0A5G2R979", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003122738", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122738", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R979", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R979-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQSNHTNVKEFVFLEITHFRELELFLFVAFLAVYVATVLGNALIVVTITCESPLHTPMYFLLRNKSVLDIAFSSVTVPKFLVDLLSERKAISYDGCMAQIFFFHFAGGADIFFLSVMAYDRYLAISKPLHYVTIMRRELWLALVVASWVGGGLHSIVQIILMLPLPFCGPNVLVAFYCDVPQVVKLACTDTFALELLMISNNGLVTLLWLLLLLGSYTSILVMLRSHSGEGRNKALSTCTSHILVVTLHFVPCVYIYCRPFSTLPMDTAVSISNTVLTPMLNPMIYTLRNQEMKSAMKRMQRWLGPFESNKLG", "length": 314, "header": "tr|A0A5G2R979-1|A0A5G2R979_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100515706 PE=3 SV=1 CANONICAL=A0A5G2R979-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R979-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979/entry#A0A5G2R979-1", "sequence": { "sequence": "MVQSNHTNVKEFVFLEITHFRELELFLFVAFLAVYVATVLGNALIVVTITCESPLHTPMYFLLRNKSVLDIAFSSVTVPKFLVDLLSERKAISYDGCMAQIFFFHFAGGADIFFLSVMAYDRYLAISKPLHYVTIMRRELWLALVVASWVGGGLHSIVQIILMLPLPFCGPNVLVAFYCDVPQVVKLACTDTFALELLMISNNGLVTLLWLLLLLGSYTSILVMLRSHSGEGRNKALSTCTSHILVVTLHFVPCVYIYCRPFSTLPMDTAVSISNTVLTPMLNPMIYTLRNQEMKSAMKRMQRWLGPFESNKLG", "length": 314, "header": "tr|A0A5G2R979-1|A0A5G2R979_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100515706 PE=3 SV=1 CANONICAL=A0A5G2R979-1" }, "locus": { "chromosome": "2", "start_pos": 11991314, "end_pos": 11990373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086075.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086075.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073631.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073631.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R979", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515706", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515706", "resource": "KEGG Pathway" }, { "id": "ssc:110255199", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255199", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZSJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or4d6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQINHTHVKEFVFLALTRFRELEFFLFSVFFLVYVTTVLGNALIVVTITSESRLHTPMYFLLRNKSVLDIVFSSITVPKLLVDLLSERKAISYNGCLTQIFFFHFAGGADIFFLSVMAYDRYLAIAKPLHYVTIMRREVWVALVVASWVGGGLHSIVQIILMLPLPFCGPNTLDAFYCDVPQVVKLACTDTFALELLLISNNGLVTLLWFLLLLGSYTIILIMLKSHSGEGRNKALSTCTSHIMVVTLHFVPCVYVYCRPFTTLPMDTAISINNTVITPMLNPMIYTLRNQEMKSAMKRLQRRLGPSESNKLG", "length": 314 }, "evidence": [ { "id": "A0A5G2R979", "url": "https://omabrowser.org/oma/group/A0A5G2R979/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NGJ1-1", "protein_name": "Olfactory receptor 4D6", "gene_name": "OR4D6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQINHTNVKEFFFLELTRSRELEFFLFVVFFAVYVATVLGNALIVVTITCESRLHTPMYFLLRNKSVLDIVFSSITVPKFLVDLLSDRKTISYNDCMAQIFFFHFAGGADIFFLSVMAYDRYLAIAKPLHYVTMMRKEVWVALVVASWVSGGLHSIIQVILMLPFPFCGPNTLDAFYCYVLQVVKLACTDTFALELFMISNNGLVTLLWFLLLLGSYTVILVMLRSHSGEGRNKALSTCTSHMLVVTLHFVPCVYIYCRPFMTLPMDTTISINNTVITPMLNPIIYSLRNQEMKSAMQRLQRRLGPSESRKWG", "length": 314 }, "evidence": [ { "id": "A0A5G2R979", "url": "https://omabrowser.org/oma/group/A0A5G2R979/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R979", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R979", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R979", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R979-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R979-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R979" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R979", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R979" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9B4-1", "uniprot_ac": "A0A5G2R9B4", "uniprot_id": "A0A5G2R9B4_PIG", "mass": { "chemical_mass": 37164.0, "monoisotopic_mass": 37164.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110259598", "type": "recommended", "evidence": [ { "id": "A0A5G2R9B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R9B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259598", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4", "locus": {} } ], "crossref": [ { "id": "A0A5G2R9B4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9B4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R9B4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVPSFSTFSISSVASVDITEKRNTTSDFILLGIFNHTRPRLFLFMIVLTMAIASLTGNALMLLLIHLDPRLHRPMYFLLSQLSLMDMMLVFTIVPKMAADYLTCNKSISPAGCGLQIFVSLTLGGGESFLLAAMSYDRYVAVCHPLRYPVLFNWQLCLQMTLGSWFLGAVDGLMQAAATLSFPFCSSHVIDHFFCEAPMLVRLACADTSVLENVMYICCVLMLLVPFSLILTSYSVILSTVLQMHSLDAHKKALATCFSHLAVVGLFYGAAIFIYMQPKSYRSANHNKIVSAFYTIFTPVLNSLIYSLRNSEVKEALKKWLGKCSNFKCHQT", "length": 333, "header": "tr|A0A5G2R9B4-1|A0A5G2R9B4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259598 PE=3 SV=1 CANONICAL=A0A5G2R9B4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4/entry#A0A5G2R9B4-1", "sequence": { "sequence": "MKVPSFSTFSISSVASVDITEKRNTTSDFILLGIFNHTRPRLFLFMIVLTMAIASLTGNALMLLLIHLDPRLHRPMYFLLSQLSLMDMMLVFTIVPKMAADYLTCNKSISPAGCGLQIFVSLTLGGGESFLLAAMSYDRYVAVCHPLRYPVLFNWQLCLQMTLGSWFLGAVDGLMQAAATLSFPFCSSHVIDHFFCEAPMLVRLACADTSVLENVMYICCVLMLLVPFSLILTSYSVILSTVLQMHSLDAHKKALATCFSHLAVVGLFYGAAIFIYMQPKSYRSANHNKIVSAFYTIFTPVLNSLIYSLRNSEVKEALKKWLGKCSNFKCHQT", "length": 333, "header": "tr|A0A5G2R9B4-1|A0A5G2R9B4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259598 PE=3 SV=1 CANONICAL=A0A5G2R9B4-1" }, "locus": { "chromosome": "2", "start_pos": 54952054, "end_pos": 54951056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081709.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081709.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072914.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072914.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9B4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9B4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 333, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9B4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9B4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9B4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 307, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 24, "end_pos": 26 }, { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RFY7-1", "uniprot_ac": "A0A5G2RFY7", "uniprot_id": "A0A5G2RFY7_PIG", "mass": { "chemical_mass": 37387.0, "monoisotopic_mass": 37387.0 }, "refseq": { "ac": "XP_005656935", "name": "ras-related protein Rab-40B isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656935" }, "gene_names": [ { "name": "RAB40B", "type": "recommended", "evidence": [ { "id": "A0A5G2RFY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ] }, { "name": "RAB40B", "type": "synonym", "evidence": [ { "id": "XP_005656935", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656935" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A5G2RFY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A5G2RFY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-40B isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005656935", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656935" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RAB40B", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7", "locus": { "chromosome": "12", "start_pos": 516962, "end_pos": 493315, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000053358", "url": "https://www.ensembl.org/id/ENSSSCG00000053358" } ] } } ], "crossref": [ { "id": "A0A5G2RFY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017133", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017133", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100522636", "url": "https://www.ncbi.nlm.nih.gov/gene/100522636", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47980", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47980", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005656935", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656935", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2Q6P1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q6P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6P1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9F8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9F8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S008", "url": "https://www.uniprot.org/uniprotkb/F1S008", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S008-1", "url": "https://www.uniprot.org/uniprotkb/F1S008-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCAVGMESSHQILWSGSPQCRHAFLPRQRSRDEAAFQKPLLDRLKSGLTRLKPTATFPVDFLNDSKENEPGKVPPSRPPGTACLALCRGLALSAGHSGPTTGGVPSASRAHKACVGKQRLLLTGCLLFSRDTSGQGRFCTIFRSYSRGAQGVVLVYDIANRWSFDGLGRWITEVNQHAPGVPKILVGNRLHLAFKRQVPTEQAQAYAERLGVTFFEVSPLCNFNITESFTELARTVLLRHGMDRLWRPSKVLSLQDLCCRAVVSCTPVHLVDRLPLPVALRGHLKSFSMASGLNARMMHGRSYSLTTCSGCKRTSLRKAKAGRPPQSPPRRRSRNGCRVS", "length": 340, "header": "tr|A0A5G2RFY7-1|A0A5G2RFY7_PIG Isoform 1 of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB40B PE=3 SV=2 CANONICAL=A0A5G2RFY7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2Q6P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7/entry#A0A5G2Q6P1-1", "sequence": { "sequence": "MRRGIRSPTSLHGLRIRRCRELWYRSQTRLGSRVAVALVEAGSCSSGSDCTPDLGTSICRECRPKRPKKAGVVLVYDIANRWSFDGLGRWITEVNQHAPGVPKILVGNRLHLAFKRQVPTEQAQAYAERLGVTFFEVSPLCNFNITESFTELARTVLLRHGMDRLWRPSKVLSLQDLCCRAVVSCTPVHLVDRLPLPVALRGHLKSFSMASGLNARMMHGRSYSLTTCSGCKRTSLRKAKAGRPPQSPPRRRSRNGCRVS", "length": 260, "header": "tr|A0A5G2Q6P1-1|A0A5G2Q6P1_PIG Computationally mapped isoform of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB40B PE=3 SV=1 CANONICAL=A0A5G2RFY7-1" }, "locus": { "chromosome": "12", "start_pos": 516371, "end_pos": 514521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085452.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085452.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059673.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059673.1" } ] } }, { "isoform_ac": "A0A5G2R9F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7/entry#A0A5G2R9F8-1", "sequence": { "sequence": "GPSGPGVPGHRHCTVPLGRVWARATARHDECRGQPGPRLRLPAQVLAGGRQRRGQGRDPGEPAGRRGRVPVRPPRRHRLRDHYHPAGRPAGKAAALHAPGVPKILVGNRLHLAFKRQVPTEQAQAYAERLGVTFFEVSPLCNFNITESFTELARTVLLRHGMDRLWRPSKVLSLQDLCCRAVVSCTPVHLVDRLPLPVALRGHLKSFSMASGLNARMMHGRSYSLTTCSGCKRTSLRKAKAGRPPQSPPRRRSRNGCRVS", "length": 260, "header": "tr|A0A5G2R9F8-1|A0A5G2RFY7_PIG Computationally mapped isoform of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB40B PE=3 SV=1 CANONICAL=A0A5G2RFY7-1" }, "locus": { "chromosome": "12", "start_pos": 516371, "end_pos": 493325, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075371.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075371.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070759.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070759.1" } ] } }, { "isoform_ac": "A0A5G2RFY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7/entry#A0A5G2RFY7-1", "sequence": { "sequence": "MCAVGMESSHQILWSGSPQCRHAFLPRQRSRDEAAFQKPLLDRLKSGLTRLKPTATFPVDFLNDSKENEPGKVPPSRPPGTACLALCRGLALSAGHSGPTTGGVPSASRAHKACVGKQRLLLTGCLLFSRDTSGQGRFCTIFRSYSRGAQGVVLVYDIANRWSFDGLGRWITEVNQHAPGVPKILVGNRLHLAFKRQVPTEQAQAYAERLGVTFFEVSPLCNFNITESFTELARTVLLRHGMDRLWRPSKVLSLQDLCCRAVVSCTPVHLVDRLPLPVALRGHLKSFSMASGLNARMMHGRSYSLTTCSGCKRTSLRKAKAGRPPQSPPRRRSRNGCRVS", "length": 340, "header": "tr|A0A5G2RFY7-1|A0A5G2RFY7_PIG Isoform 1 of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB40B PE=3 SV=2 CANONICAL=A0A5G2RFY7-1" }, "locus": { "chromosome": "12", "start_pos": 516371, "end_pos": 513509, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084707.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084707.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070029.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070029.2" } ] } }, { "isoform_ac": "F1S008-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7/entry#F1S008-1", "sequence": { "sequence": "GLWGPSGPGVPGHRHCTVPLGRVWARATARHDECRGQPGPRLRLPAQVLAGGRQRRGQGRDPGEPAGRRGRVPVRPPRRHRLRDHYHPAGRPAGKAAALGVVLVYDIANRWSFDGLGRWITEVNQHAPGVPKILVGNRLHLAFKRQVPTEQAQAYAERLGVTFFEVSPLCNFNITESFTELARTVLLRHGMDRLWRPSKVLSLQDLCCRAVVSCTPVHLVDRLPLPVALRGHLKSFSMASGLNARMMHGRSYSLTTCSGCKRTSLRKAKAGRPPQSPPRRRSRNGCRVS", "length": 289, "header": "tr|F1S008-1|A0A5G2RFY7_PIG Computationally mapped isoform of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB40B PE=3 SV=5 CANONICAL=A0A5G2RFY7-1" }, "locus": { "chromosome": "12", "start_pos": 516371, "end_pos": 493316, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018647.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018647.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018146.5", "url": "https://www.ensembl.org/id/ENSSSCP00000018146.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 100, "start_aa": "Thr", "end_pos": 100, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr100", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S008", "url": "https://www.uniprot.org/uniprotkb/F1S008" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "lamellipodium membrane", "id": "GO:0031258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031258", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "negative regulation of actin filament bundle assembly", "id": "GO:0032232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032232", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "cellular detoxification", "id": "GO:1990748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990748", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" }, { "name": "regulation of lamellipodium organization", "id": "GO:1902743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902743", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RFY7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 340, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RFY7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFY7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RFY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFY7" }, { "id": "PS50225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SOCS box", "eco_id": "ECO_0000259", "start_pos": 237, "end_pos": 290, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 100 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9G1-1", "uniprot_ac": "A0A5G2R9G1", "uniprot_id": "A0A5G2R9G1_PIG", "mass": { "chemical_mass": 34549.0, "monoisotopic_mass": 34549.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "LINE-1 type transposase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2R9G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9G1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1", "locus": {} } ], "crossref": [ { "id": "A0A5G2R9G1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9G1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041209", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041209", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R9G1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSLTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIGGEIKIFPNKQKLKEYSNTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2R9G1-1|A0A5G2R9G1_PIG Isoform 1 of LINE-1 type transposase domain-containing protein 1 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R9G1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1/entry#A0A5G2R9G1-1", "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSLTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIGGEIKIFPNKQKLKEYSNTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2R9G1-1|A0A5G2R9G1_PIG Isoform 1 of LINE-1 type transposase domain-containing protein 1 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R9G1-1" }, "locus": { "chromosome": "4", "start_pos": 87575770, "end_pos": 87574883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090232.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090232.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067240.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067240.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9G1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9G1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9G1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9G1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9G1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 296, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9G1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9G1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 227, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R9G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1" }, { "id": "PF17490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element dsRBD-like", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 293, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R9G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9G1" }, { "id": "PF17489", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element trimerization", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 128, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9H1-1", "uniprot_ac": "A0A5G2R9H1", "uniprot_id": "A0A5G2R9H1_PIG", "mass": { "chemical_mass": 31904.0, "monoisotopic_mass": 31904.0 }, "refseq": { "ac": "XP_020937336", "name": "olfactory receptor 6C76-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937336" }, "gene_names": [ { "name": "LOC106507486", "type": "recommended", "evidence": [ { "id": "A0A5G2R9H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1" } ] }, { "name": "LOC106507486", "type": "synonym", "evidence": [ { "id": "XP_020937336", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937336" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R9H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6C76-like", "type": "synonym", "evidence": [ { "id": "XP_020937336", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937336" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9H1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9H1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC106507486", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1", "locus": {} } ], "crossref": [ { "id": "A0A5G2R9H1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9H1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050305", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050305", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "106507486", "url": "https://www.ncbi.nlm.nih.gov/gene/106507486", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:106507486", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106507486", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R9H1", "url": "https://www.orthodb.org/?gene=A0A5G2R9H1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020937336", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937336", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R9H1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNYTSVNEFILLGLTDDPKLNVLIFLFLFFTYILSITGNLTIITLTLIESHLKTPMYFFLRNFSFLEISFTTVCIPRFLVSIVTGDRTISYHSCMAQVFFFILLGATEFFLLTAMSYDWYVAIWKPLHYTTIMNSRICNQLVVSSWLAGFLIIFPPVIMGLQLDFCDSNIIDHFTCDSSPMLLISCTDTAFLELMAFFLATFMLMVTLTLVILSYAFILKTILRIPSAEQRKKAFSTCSSHIIVVSISYGSCIFMYVKTSAKEGGALTKGIAVLIPLLSQC", "length": 282, "header": "tr|A0A5G2R9H1-1|A0A5G2R9H1_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC106507486 PE=3 SV=1 CANONICAL=A0A5G2R9H1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1/entry#A0A5G2R9H1-1", "sequence": { "sequence": "MKNYTSVNEFILLGLTDDPKLNVLIFLFLFFTYILSITGNLTIITLTLIESHLKTPMYFFLRNFSFLEISFTTVCIPRFLVSIVTGDRTISYHSCMAQVFFFILLGATEFFLLTAMSYDWYVAIWKPLHYTTIMNSRICNQLVVSSWLAGFLIIFPPVIMGLQLDFCDSNIIDHFTCDSSPMLLISCTDTAFLELMAFFLATFMLMVTLTLVILSYAFILKTILRIPSAEQRKKAFSTCSSHIIVVSISYGSCIFMYVKTSAKEGGALTKGIAVLIPLLSQC", "length": 282, "header": "tr|A0A5G2R9H1-1|A0A5G2R9H1_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC106507486 PE=3 SV=1 CANONICAL=A0A5G2R9H1-1" }, "locus": { "chromosome": "AEMK02000577.1", "start_pos": 379, "end_pos": -165, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082042.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082042.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070774.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070774.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9H1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:106507486", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106507486", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9H1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9H1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9H1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9H1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 282, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9H1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9H1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9H1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 282, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9J5-1", "uniprot_ac": "A0A5G2R9J5", "uniprot_id": "A0A5G2R9J5_PIG", "mass": { "chemical_mass": 8786.0, "monoisotopic_mass": 8786.0 }, "refseq": {}, "gene_names": [ { "name": "ERGIC1", "type": "recommended", "evidence": [ { "id": "A0A5G2R9J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5" } ] } ], "protein_names": [ { "name": "Endoplasmic reticulum-Golgi intermediate compartment protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R9J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in transport between endoplasmic reticulum and Golgi.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9J5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5#function" }, { "database": "UniProtKB", "id": "RU369013", "url": "https://www.uniprot.org/uniprotkb/RU369013#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9J5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ERGIC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5", "locus": { "chromosome": "16", "start_pos": 51285493, "end_pos": 51330169, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016988", "url": "https://www.ensembl.org/id/ENSSSCG00000016988" } ] } } ], "crossref": [ { "id": "A0A5G2R9J5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9J5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016988", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016988", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR039542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045888", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045888", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10984", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10984", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10984:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10984:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13850", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13850", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R9J5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFIFFLFLSELTGFITTEMPTLGEESVRASWQRLTHGESIPDS", "length": 76, "header": "tr|A0A5G2R9J5-1|A0A5G2R9J5_PIG Isoform 1 of Endoplasmic reticulum-Golgi intermediate compartment protein OS=Sus scrofa OX=9823 GN=ERGIC1 PE=3 SV=2 CANONICAL=A0A5G2R9J5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5/entry#A0A5G2R9J5-1", "sequence": { "sequence": "MPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFIFFLFLSELTGFITTEMPTLGEESVRASWQRLTHGESIPDS", "length": 76, "header": "tr|A0A5G2R9J5-1|A0A5G2R9J5_PIG Isoform 1 of Endoplasmic reticulum-Golgi intermediate compartment protein OS=Sus scrofa OX=9823 GN=ERGIC1 PE=3 SV=2 CANONICAL=A0A5G2R9J5-1" }, "locus": { "chromosome": "16", "start_pos": 51403382, "end_pos": 51340162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073222.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073222.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070799.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070799.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9J5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9J5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9J5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9J5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9J5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9J5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 76, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9J5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9J5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9J5" }, { "id": "PF13850", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endoplasmic reticulum vesicle transporter N-terminal", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 52, "start_aa": "Phe", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9L7-1", "uniprot_ac": "A0A5G2R9L7", "uniprot_id": "A0A5G2R9L7_PIG", "mass": { "chemical_mass": 29423.0, "monoisotopic_mass": 29423.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "L1 transposable element RRM domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2R9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9L7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9L7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9L7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9L7", "locus": {} } ], "crossref": [ { "id": "A0A5G2R9L7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9L7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041184", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041184", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R9L7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRQRTITQMREKEKTPENQLSDQESLSLQEKDFRLLVQKMMQDIGNKLEAKMDNLQETLTREIQDIKLKQEEMQNTITEIKNSFEAANSRIQEAEEQISEVEDRLVEITDAEQKREKRLKANEESLRELWDNVKRTNICIIGVPEGEEREKETEKIFQEIIAENFPNMGKEPLSQIQEAQRVPYKINPRRNTLRHILIKLTKIKDKGKILKAAREKKQIIYKGTLIRLSADISGETLQARPEGSGMIYLM", "length": 251, "header": "tr|A0A5G2R9L7-1|A0A5G2R9L7_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R9L7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9L7/entry#A0A5G2R9L7-1", "sequence": { "sequence": "MKRQRTITQMREKEKTPENQLSDQESLSLQEKDFRLLVQKMMQDIGNKLEAKMDNLQETLTREIQDIKLKQEEMQNTITEIKNSFEAANSRIQEAEEQISEVEDRLVEITDAEQKREKRLKANEESLRELWDNVKRTNICIIGVPEGEEREKETEKIFQEIIAENFPNMGKEPLSQIQEAQRVPYKINPRRNTLRHILIKLTKIKDKGKILKAAREKKQIIYKGTLIRLSADISGETLQARPEGSGMIYLM", "length": 251, "header": "tr|A0A5G2R9L7-1|A0A5G2R9L7_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R9L7-1" }, "locus": { "chromosome": "16", "start_pos": 67963589, "end_pos": 67962837, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090550.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090550.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073994.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073994.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9L7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9L7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9L7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9L7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9L7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9L7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9L7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9L7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9L7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 251, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9L7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9L7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9L7" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 232, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2R9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9L7" }, { "id": "PF17489", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element trimerization", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 132, "start_aa": "Glu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9P1-1", "uniprot_ac": "A0A5G2R9P1", "uniprot_id": "A0A5G2R9P1_PIG", "mass": { "chemical_mass": 33790.0, "monoisotopic_mass": 33790.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R9P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9P1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9P1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1", "locus": {} } ], "crossref": [ { "id": "A0A5G2R9P1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9P1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000046090", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000046090", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R9P1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTANNGTAVEEFVLQSFSEEPGPRILFLAVFLLLYLGALAGNALIVTAISLHPGLHTPMYFFLTNLAILDIVCTSTVVPKLLENLALKGGTITYQGCMTQLFFLTWCLAAELLLLTVMAYDRYVAICRPLHYSRLMGRPVCALLAGSVWAITVLNTSVHTGLMTRLMFCGHNQIQHFLCEIPTLLLLSCSPTTLNNVMMVLADVYFGVVNFLLTLASYAYIIASIVRMRSATGRQRAFSTCSSHLLVVTLYYSTVIYTYILPGSGSSLENGKVVAVLYTAVSPTLNPLIYSLRNKDVKVALGRLLSYC", "length": 308, "header": "tr|A0A5G2R9P1-1|A0A5G2R9P1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2R9P1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1/entry#A0A5G2R9P1-1", "sequence": { "sequence": "MTANNGTAVEEFVLQSFSEEPGPRILFLAVFLLLYLGALAGNALIVTAISLHPGLHTPMYFFLTNLAILDIVCTSTVVPKLLENLALKGGTITYQGCMTQLFFLTWCLAAELLLLTVMAYDRYVAICRPLHYSRLMGRPVCALLAGSVWAITVLNTSVHTGLMTRLMFCGHNQIQHFLCEIPTLLLLSCSPTTLNNVMMVLADVYFGVVNFLLTLASYAYIIASIVRMRSATGRQRAFSTCSSHLLVVTLYYSTVIYTYILPGSGSSLENGKVVAVLYTAVSPTLNPLIYSLRNKDVKVALGRLLSYC", "length": 308, "header": "tr|A0A5G2R9P1-1|A0A5G2R9P1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2R9P1-1" }, "locus": { "chromosome": "14", "start_pos": 141529897, "end_pos": 141505895, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068316.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068316.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067315.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067315.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9P1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9P1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9P1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9P1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9P1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9P1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 308, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9P1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9P1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9P1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9T6-1", "uniprot_ac": "A0A5G2R9T6", "uniprot_id": "A0A5G2R9T6_PIG", "mass": { "chemical_mass": 35500.0, "monoisotopic_mass": 35500.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2R9T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6", "locus": {} } ], "crossref": [ { "id": "A0A5G2R9T6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9T6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044604", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044604", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15237", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15237", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R9T6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PADLRNGSTVTEFVLVGFEQSSPSTRALLFALFLALYSLAMAMNGLIIFITWTDPRLSSPMYFFLGHLSFLDVCFITTTIPQMLIHLVVKNHSVSFVACMTQTYLVFFVGVAECILLAFMAYDRYVAICHPLNYAQIMSRQVCVRLVSTAWFFGLINGLFLEYMSFRNPFCRGHHIENFFCEAPVVIALSCGDPRFSLKMVFADAIVVLLSPMVLIVISYARILTSILGRASSSGRGKTFSTCASHLTVVTCLYTSAMFSYMNPRSTHGPDKDKPFSLLYTIITPMCNPIIYSFRNKEMKGAMVRALGRSSLAQARSV", "length": 318, "header": "tr|A0A5G2R9T6-1|A0A5G2R9T6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R9T6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6/entry#A0A5G2R9T6-1", "sequence": { "sequence": "PADLRNGSTVTEFVLVGFEQSSPSTRALLFALFLALYSLAMAMNGLIIFITWTDPRLSSPMYFFLGHLSFLDVCFITTTIPQMLIHLVVKNHSVSFVACMTQTYLVFFVGVAECILLAFMAYDRYVAICHPLNYAQIMSRQVCVRLVSTAWFFGLINGLFLEYMSFRNPFCRGHHIENFFCEAPVVIALSCGDPRFSLKMVFADAIVVLLSPMVLIVISYARILTSILGRASSSGRGKTFSTCASHLTVVTCLYTSAMFSYMNPRSTHGPDKDKPFSLLYTIITPMCNPIIYSFRNKEMKGAMVRALGRSSLAQARSV", "length": 318, "header": "tr|A0A5G2R9T6-1|A0A5G2R9T6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2R9T6-1" }, "locus": { "chromosome": "5", "start_pos": 78576872, "end_pos": 78575919, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073748.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073748.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074064.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074064.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9T6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 318, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9T6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9T6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 292, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9T7-1", "uniprot_ac": "A0A5G2R9T7", "uniprot_id": "A0A5G2R9T7_PIG", "mass": { "chemical_mass": 28386.0, "monoisotopic_mass": 28386.0 }, "refseq": {}, "gene_names": [ { "name": "CYB561", "type": "recommended", "evidence": [ { "id": "A0A5G2R9T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7" } ] } ], "protein_names": [ { "name": "Transmembrane ascorbate-dependent reductase CYB561", "type": "recommended", "evidence": [ { "id": "A0A5G2R9T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome b-561", "type": "synonym", "evidence": [ { "id": "A0A5G2R9T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome b561", "type": "synonym", "evidence": [ { "id": "A0A5G2R9T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CYB561", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7", "locus": { "chromosome": "12", "start_pos": 15447100, "end_pos": 15436803, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017297", "url": "https://www.ensembl.org/id/ENSSSCG00000017297" } ] } } ], "crossref": [ { "id": "A0A5G2R9T7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9T7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017297", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017297", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043205", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043205", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10106:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10106:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R9T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RE21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RE21-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRW2", "url": "https://www.uniprot.org/uniprotkb/F1RRW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRW2-1", "url": "https://www.uniprot.org/uniprotkb/F1RRW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ESGSRLSMESPAGRTPAPRALPYYVAFSQLLGLTVVAVTGAWLGAYRGGIAWESALQFNVHPLCMIIGLVFLQGDALLVYRVFRNEAKRTTKILHGLLHVLAFVIALVGLVAVFDYHRKKGIADLYSLHSWCGILVFVLFLAQWLVGLGFFLFPGASFSLRSRYRPQHVFFGAAIFLLSVGTALLGLKEALLFQLGTKYSAFESEGILANVLGLLLVAFGAVVLYILTRADWKRPLQAEEQALSMDFKTLTEGDSPSSQ", "length": 259, "header": "tr|A0A5G2R9T7-1|A0A5G2R9T7_PIG Isoform 1 of Transmembrane ascorbate-dependent reductase CYB561 OS=Sus scrofa OX=9823 GN=CYB561 PE=4 SV=1 CANONICAL=A0A5G2R9T7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7/entry#A0A5G2R9T7-1", "sequence": { "sequence": "ESGSRLSMESPAGRTPAPRALPYYVAFSQLLGLTVVAVTGAWLGAYRGGIAWESALQFNVHPLCMIIGLVFLQGDALLVYRVFRNEAKRTTKILHGLLHVLAFVIALVGLVAVFDYHRKKGIADLYSLHSWCGILVFVLFLAQWLVGLGFFLFPGASFSLRSRYRPQHVFFGAAIFLLSVGTALLGLKEALLFQLGTKYSAFESEGILANVLGLLLVAFGAVVLYILTRADWKRPLQAEEQALSMDFKTLTEGDSPSSQ", "length": 259, "header": "tr|A0A5G2R9T7-1|A0A5G2R9T7_PIG Isoform 1 of Transmembrane ascorbate-dependent reductase CYB561 OS=Sus scrofa OX=9823 GN=CYB561 PE=4 SV=1 CANONICAL=A0A5G2R9T7-1" }, "locus": { "chromosome": "12", "start_pos": 15445523, "end_pos": 15441358, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087303.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087303.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073079.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073079.1" } ] } }, { "isoform_ac": "A0A5G2RE21-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7/entry#A0A5G2RE21-1", "sequence": { "sequence": "TQWTLKLCGISVCPQNKPKTRPGIHRTADQRWWAGAGVVAPGRAPSAPLLVYRVFRNEAKRTTKILHGLLHVLAFVIALVGLVAVFDYHRKKGIADLYSLHSWCGILVFVLFLAQWLVGLGFFLFPGASFSLRSRYRPQHVFFGAAIFLLSVGTALLGLKEALLFQLGTKYSAFESEGILANVLGLLLVAFGAVVLYILTRADWKRPLQAEEQALSMDFKTLTEGDSPSSQ", "length": 231, "header": "tr|A0A5G2RE21-1|A0A5G2RE21_PIG Computationally mapped isoform of Transmembrane ascorbate-dependent reductase CYB561 OS=Sus scrofa OX=9823 GN=CYB561 PE=4 SV=1 CANONICAL=A0A5G2R9T7-1" }, "locus": { "chromosome": "12", "start_pos": 15445523, "end_pos": 15444083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078450.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078450.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072806.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072806.1" } ] } }, { "isoform_ac": "F1RRW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7/entry#F1RRW2-1", "sequence": { "sequence": "MESPAGRTPAPRALPYYVAFSQLLGLTVVAVTGAWLGAYRGGIAWESALQFNVHPLCMIIGLVFLQGDALLVYRVFRNEAKRTTKILHGLLHVLAFVIALVGLVAVFDYHRKKGIADLYSLHSWCGILVFVLFLAQDQVQRVRVRGHPGQRAGPAAGRLRRGRALHPDPRRLEAAPPGGRASALHGLQDADGGRQSQLPVTAEPGRGDGRRGQPCSPGR", "length": 219, "header": "tr|F1RRW2-1|A0A5G2R9T7_PIG Computationally mapped isoform of Transmembrane ascorbate-dependent reductase CYB561 OS=Sus scrofa OX=9823 GN=CYB561 PE=4 SV=3 CANONICAL=A0A5G2R9T7-1" }, "locus": { "chromosome": "12", "start_pos": 15445582, "end_pos": 15443249, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018831.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018831.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018329.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018329.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RRW2", "url": "https://www.uniprot.org/uniprotkb/F1RRW2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7" } ], "pmid": "" }, { "name": "transmembrane monodehydroascorbate reductase activity", "id": "GO:0140575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140575", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7" } ], "pmid": "" }, { "name": "chromaffin granule membrane", "id": "GO:0042584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042584", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7" } ], "pmid": "" }, { "name": "ascorbate homeostasis", "id": "GO:0140576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140576", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9T7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9T7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 259, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9T7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9T7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9T7" }, { "id": "PS50939", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50939" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytochrome b561", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 228, "start_aa": "Phe", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9U1-1", "uniprot_ac": "A0A5G2R9U1", "uniprot_id": "A0A5G2R9U1_PIG", "mass": { "chemical_mass": 136065.0, "monoisotopic_mass": 136065.0 }, "refseq": { "ac": "XP_020921021", "name": "protocadherin-9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921021" }, "gene_names": [ { "name": "PCDH9", "type": "recommended", "evidence": [ { "id": "A0A5G2R9U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1" } ] }, { "name": "PCDH9", "type": "synonym", "evidence": [ { "id": "XP_020921021", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921021" } ] } ], "protein_names": [ { "name": "Protocadherin 9", "type": "synonym", "evidence": [ { "id": "A0A5G2R9U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1/entry#names_and_taxonomy" } ] }, { "name": "protocadherin-9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020921021", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921021" } ] } ], "function": [ { "annotation": "Potential calcium-dependent cell-adhesion protein.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9U1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1#function" }, { "database": "UniProtKB", "id": "ARBA00037723", "url": "https://www.uniprot.org/uniprotkb/ARBA00037723#function" }, { "database": "UniProtKB", "id": "F1RJ39", "url": "https://www.uniprot.org/uniprotkb/F1RJ39#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9U1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PCDH9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1", "locus": { "chromosome": "11", "start_pos": 38523033, "end_pos": 39453741, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000038842", "url": "https://www.ensembl.org/id/ENSSSCG00000038842" } ] } } ], "crossref": [ { "id": "A0A5G2R9U1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9U1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000038842", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000038842", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "106505308", "url": "https://www.ncbi.nlm.nih.gov/gene/106505308", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:106505308", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106505308", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R9U1", "url": "https://www.orthodb.org/?gene=A0A5G2R9U1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF248", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF248", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08374", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08374", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020921021", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921021", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R9U1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RJ39", "url": "https://www.uniprot.org/uniprotkb/F1RJ39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RJ39-1", "url": "https://www.uniprot.org/uniprotkb/F1RJ39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQCNSHSKSDNIPVTPKKCPSSTGFHNQENEEGHYESQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPSLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDRKQYGSTEGHFNNGSHMTDIPLANLKSYKQAGGAIESPKEHQL", "length": 1237, "header": "tr|A0A5G2R9U1-1|A0A5G2R9U1_PIG Isoform 1 of Protocadherin 9 OS=Sus scrofa OX=9823 GN=PCDH9 PE=4 SV=1 CANONICAL=A0A5G2R9U1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1/entry#A0A5G2R9U1-1", "sequence": { "sequence": "MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQCNSHSKSDNIPVTPKKCPSSTGFHNQENEEGHYESQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPSLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDRKQYGSTEGHFNNGSHMTDIPLANLKSYKQAGGAIESPKEHQL", "length": 1237, "header": "tr|A0A5G2R9U1-1|A0A5G2R9U1_PIG Isoform 1 of Protocadherin 9 OS=Sus scrofa OX=9823 GN=PCDH9 PE=4 SV=1 CANONICAL=A0A5G2R9U1-1" }, "locus": { "chromosome": "11", "start_pos": 39452343, "end_pos": 38524037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075301.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075301.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074069.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074069.1" } ] } }, { "isoform_ac": "F1RJ39-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1/entry#F1RJ39-1", "sequence": { "sequence": "MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPSLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDRKQYGSTEGHFNNGSHMTDIPLANLKSYKQAGGAIESPKEHQL", "length": 1203, "header": "tr|F1RJ39-1|A0A5G2R9U1_PIG Computationally mapped isoform of Protocadherin 9 OS=Sus scrofa OX=9823 GN=PCDH9 PE=4 SV=3 CANONICAL=A0A5G2R9U1-1" }, "locus": { "chromosome": "11", "start_pos": 39452343, "end_pos": 38524037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048711.2", "url": "https://www.ensembl.org/id/ENSSSCT00000048711.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040755.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040755.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RJ39", "url": "https://www.uniprot.org/uniprotkb/F1RJ39" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:106505308", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106505308", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9U1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9U1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9U1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9U1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9U1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9U1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1207, "end_pos": 1209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 754, "end_pos": 756, "annotation": "n_glycosylation_sequon" }, { "start_pos": 775, "end_pos": 777, "annotation": "n_glycosylation_sequon" }, { "start_pos": 780, "end_pos": 782, "annotation": "n_glycosylation_sequon" }, { "start_pos": 901, "end_pos": 903, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9U1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1237, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9U1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9U1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9U1" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 142, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1207, "end_pos": 1209 }, { "start_pos": 148, "end_pos": 150 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 511, "end_pos": 513 }, { "start_pos": 547, "end_pos": 549 }, { "start_pos": 630, "end_pos": 632 }, { "start_pos": 681, "end_pos": 683 }, { "start_pos": 734, "end_pos": 736 }, { "start_pos": 754, "end_pos": 756 }, { "start_pos": 775, "end_pos": 777 }, { "start_pos": 780, "end_pos": 782 }, { "start_pos": 901, "end_pos": 903 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R9Y3-1", "uniprot_ac": "A0A5G2R9Y3", "uniprot_id": "A0A5G2R9Y3_PIG", "mass": { "chemical_mass": 53566.0, "monoisotopic_mass": 53566.0 }, "refseq": { "ac": "XP_003129141", "name": "starch-binding domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129141" }, "gene_names": [ { "name": "STBD1", "type": "synonym", "evidence": [ { "id": "XP_003129141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129141" } ] } ], "protein_names": [ { "name": "Starch-binding domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2R9Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3/entry#names_and_taxonomy" } ] }, { "name": "Genethonin-1", "type": "synonym", "evidence": [ { "id": "A0A5G2R9Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3/entry#names_and_taxonomy" } ] }, { "name": "Glycophagy cargo receptor stbd1", "type": "synonym", "evidence": [ { "id": "A0A5G2R9Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3/entry#names_and_taxonomy" } ] }, { "name": "starch-binding domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_003129141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129141" } ] } ], "function": [ { "annotation": "Acts as a cargo receptor for glycogen. Delivers its cargo to an autophagic pathway called glycophagy, resulting in the transport of glycogen to lysosomes.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3#function" }, { "database": "UniProtKB", "id": "ARBA00053886", "url": "https://www.uniprot.org/uniprotkb/ARBA00053886#function" }, { "database": "UniProtKB", "id": "F1RYS9", "url": "https://www.uniprot.org/uniprotkb/F1RYS9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3", "locus": {} } ], "crossref": [ { "id": "A0A5G2R9Y3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9Y3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008981", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008981", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05813", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05813", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522745", "url": "https://www.ncbi.nlm.nih.gov/gene/100522745", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013784", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013784", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522745", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522745", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R9Y3", "url": "https://www.orthodb.org/?gene=A0A5G2R9Y3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15048:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15048:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46449", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46449", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46449:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46449:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003129141", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129141", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYS9", "url": "https://www.uniprot.org/uniprotkb/F1RYS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYS9-1", "url": "https://www.uniprot.org/uniprotkb/F1RYS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFVKRRRRGARNCPKQGWAWRAAAAGRAGGVAGAGWRAEAVRPGVLSHAGRTWTRTPSAPGRRRPAGSGREEVGEGGRSRIRRAGAWGCSPGAGSGAGLGKLSVSRGGLGSAWERLRPGTVKGWSGLGRCGSACVTRARASIAVVSRSCGLSAMGAVWSALLVGGGLAGALFVWLLRDTGKEGDAEQRKDAPSGEAAAPGGDQGGGGGLSPGPSRREPVTKPEHPQESNGCLVSETKGPGDLQEAARRQQGPSGEGGNCDSSRAHVPSGKFPDTGSLATSESSHAGSYSDVSSTESLGSPVGAWRFQKGQETPTKAAPCLAEKSPSGNLLLDRGKEVSLAQSDSQARADHEDWEMVARHSSWGDVGLGGSLEAPVLSSNQGKDYGRRTLVEARAQEVDVKRKKVAGVSWESRKVSIRFQVHYITGAGMQFIAVTGDHESLGRWKAYIPLQCSQDGLWSRSVPLPADTGVEWKFVVVENGEVTRWEECSNRFLETGHEDQVVHKWWGIH", "length": 508, "header": "tr|A0A5G2R9Y3-1|A0A5G2R9Y3_PIG Isoform 1 of Starch-binding domain-containing protein 1 OS=Sus scrofa OX=9823 GN= PE=1 SV=1 CANONICAL=A0A5G2R9Y3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3/entry#A0A5G2R9Y3-1", "sequence": { "sequence": "MFVKRRRRGARNCPKQGWAWRAAAAGRAGGVAGAGWRAEAVRPGVLSHAGRTWTRTPSAPGRRRPAGSGREEVGEGGRSRIRRAGAWGCSPGAGSGAGLGKLSVSRGGLGSAWERLRPGTVKGWSGLGRCGSACVTRARASIAVVSRSCGLSAMGAVWSALLVGGGLAGALFVWLLRDTGKEGDAEQRKDAPSGEAAAPGGDQGGGGGLSPGPSRREPVTKPEHPQESNGCLVSETKGPGDLQEAARRQQGPSGEGGNCDSSRAHVPSGKFPDTGSLATSESSHAGSYSDVSSTESLGSPVGAWRFQKGQETPTKAAPCLAEKSPSGNLLLDRGKEVSLAQSDSQARADHEDWEMVARHSSWGDVGLGGSLEAPVLSSNQGKDYGRRTLVEARAQEVDVKRKKVAGVSWESRKVSIRFQVHYITGAGMQFIAVTGDHESLGRWKAYIPLQCSQDGLWSRSVPLPADTGVEWKFVVVENGEVTRWEECSNRFLETGHEDQVVHKWWGIH", "length": 508, "header": "tr|A0A5G2R9Y3-1|A0A5G2R9Y3_PIG Isoform 1 of Starch-binding domain-containing protein 1 OS=Sus scrofa OX=9823 GN= PE=1 SV=1 CANONICAL=A0A5G2R9Y3-1" }, "locus": { "chromosome": "8", "start_pos": 71986564, "end_pos": 71983170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082425.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082425.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073856.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073856.1" } ] } }, { "isoform_ac": "F1RYS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3/entry#F1RYS9-1", "sequence": { "sequence": "MRDALGPGRPVLPAAGDRRGREGKSCGLSAMGAVWSALLVGGGLAGALFVWLLRDTGKEGDAEQRKDAPSGEAAAPGGDQGGGGGLSPGPSRREPVTKPEHPQESNGCLVSETKGPGDLQEAARRQQGPSGEGGNCDSSRAHVPSGKFPDTGSLATSESSHAGSYSDVSSTESLGSPVGAWRFQKGQETPTKAAPCLAEKSPSGNLLLDRGKEVSLAQSDSQARADHEDWEMVARHSSWGDVGLGGSLEAPVLSSNQGKDYGRRTLVEARAQEVDVKRKKVAGVSWESRKVSIRFQVHYITGAGMQFIAVTGDHESLGRWKAYIPLQCSQDGLWSRSVPLPADTGVEWKFVVVENGEVTRWEECSNRFLETGHEDQVVHKWWGIH", "length": 385, "header": "tr|F1RYS9-1|A0A5G2R9Y3_PIG Computationally mapped isoform of Starch-binding domain-containing protein 1 OS=Sus scrofa OX=9823 GN= PE=1 SV=3 CANONICAL=A0A5G2R9Y3-1" }, "locus": { "chromosome": "8", "start_pos": 71986564, "end_pos": 71983312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009839.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009839.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009586.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009586.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RYS9", "url": "https://www.uniprot.org/uniprotkb/F1RYS9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522745", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522745", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3" } ], "pmid": "" }, { "name": "T-tubule", "id": "GO:0030315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030315", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3" } ], "pmid": "" }, { "name": "glycophagy", "id": "GO:0061723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "starch binding", "id": "GO:2001070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001070", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3" } ], "pmid": "" }, { "name": "glycogen binding", "id": "GO:2001069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001069", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R9Y3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 508, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R9Y3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R9Y3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R9Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9Y3" }, { "id": "PS51166", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51166" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBM20", "eco_id": "ECO_0000259", "start_pos": 408, "end_pos": 507, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RA33-1", "uniprot_ac": "A0A5G2RA33", "uniprot_id": "A0A5G2RA33_PIG", "mass": { "chemical_mass": 36590.0, "monoisotopic_mass": 36590.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Taste receptor type 2", "type": "recommended", "evidence": [ { "id": "A0A5G2RA33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA33/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA33", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA33" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA33", "locus": {} } ], "crossref": [ { "id": "A0A5G2RA33", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RA33", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13950", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13950", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11394:SF76", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11394:SF76", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05296", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05296", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RA33", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RA33-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PKNFLLLPEDTLENILMIIYAVIFLVGILGNGFILLVNCIDWIKNRRFSLMDCILTCLAISRIFMLCIIILSIGLHVISVTIWCNNDLLISLENLWIGSNYFCTVCTTCLSVFYFLKIANFSNLLFLWMKWRIHKVLLIIVLGAALSFGLSLLFKDTVVKILLKNQIDAENNVTLYFSERKHILTSHLFLGTMFIIPFVVSLTSFVLLILSLWSHLRHMKSTVSRDTSTEAHVRAMKSMISFLLLFILYYASNILLMWGYGRQDNFVVKIFSNVLLFFYPSGHPFLMILWNSKLKQASLRILRKLNCSMNPRKPTLP", "length": 317, "header": "tr|A0A5G2RA33-1|A0A5G2RA33_PIG Isoform 1 of Taste receptor type 2 OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RA33-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RA33-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA33/entry#A0A5G2RA33-1", "sequence": { "sequence": "PKNFLLLPEDTLENILMIIYAVIFLVGILGNGFILLVNCIDWIKNRRFSLMDCILTCLAISRIFMLCIIILSIGLHVISVTIWCNNDLLISLENLWIGSNYFCTVCTTCLSVFYFLKIANFSNLLFLWMKWRIHKVLLIIVLGAALSFGLSLLFKDTVVKILLKNQIDAENNVTLYFSERKHILTSHLFLGTMFIIPFVVSLTSFVLLILSLWSHLRHMKSTVSRDTSTEAHVRAMKSMISFLLLFILYYASNILLMWGYGRQDNFVVKIFSNVLLFFYPSGHPFLMILWNSKLKQASLRILRKLNCSMNPRKPTLP", "length": 317, "header": "tr|A0A5G2RA33-1|A0A5G2RA33_PIG Isoform 1 of Taste receptor type 2 OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RA33-1" }, "locus": { "chromosome": "5", "start_pos": 61218284, "end_pos": 61216785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089410.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089410.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067471.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067471.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA33", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA33" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA33", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA33" } ], "pmid": "" }, { "name": "bitter taste receptor activity", "id": "GO:0033038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033038", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA33", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA33" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA33", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA33" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of bitter taste", "id": "GO:0001580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001580", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA33", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA33" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RA33-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 317, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RA33-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RA33" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 306, "end_pos": 308 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RA86-1", "uniprot_ac": "A0A5G2RA86", "uniprot_id": "A0A5G2RA86_PIG", "mass": { "chemical_mass": 32976.0, "monoisotopic_mass": 32976.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Vomeronasal type-1 receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RA86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA86/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA86" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA86", "locus": {} } ], "crossref": [ { "id": "A0A5G2RA86", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RA86", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24062", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24062", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RA86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RA86-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VNENNKLSRFIDIRNAFFSEVGTGVSANTMLLFHILTFLLEHRLKPMDLAIGHLALFHLFMLLTVAFMASDIFGSQKTWDDIKCKLVLYLYRLMRVTQAITLSPRNSCLAKFKHESSHHNLYYILFLWVSNMATSSNFLVSIIATPNVTVTHLLFVTKSFSLYPMIYFLRYLYFALVTFQDVSMLVLMALSSGYMVILLYRHQKQTWHLHSTKLSLKASPEKKGHPDHSVAHEMLWNNNPVHLCVHMLVRNGYASISPLVLIIPILAHQVKDSIHVCKDVDSIPGLAQ", "length": 288, "header": "tr|A0A5G2RA86-1|A0A5G2RA86_PIG Isoform 1 of Vomeronasal type-1 receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RA86-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RA86-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA86/entry#A0A5G2RA86-1", "sequence": { "sequence": "VNENNKLSRFIDIRNAFFSEVGTGVSANTMLLFHILTFLLEHRLKPMDLAIGHLALFHLFMLLTVAFMASDIFGSQKTWDDIKCKLVLYLYRLMRVTQAITLSPRNSCLAKFKHESSHHNLYYILFLWVSNMATSSNFLVSIIATPNVTVTHLLFVTKSFSLYPMIYFLRYLYFALVTFQDVSMLVLMALSSGYMVILLYRHQKQTWHLHSTKLSLKASPEKKGHPDHSVAHEMLWNNNPVHLCVHMLVRNGYASISPLVLIIPILAHQVKDSIHVCKDVDSIPGLAQ", "length": 288, "header": "tr|A0A5G2RA86-1|A0A5G2RA86_PIG Isoform 1 of Vomeronasal type-1 receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RA86-1" }, "locus": { "chromosome": "13", "start_pos": 70507617, "end_pos": 70506527, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090980.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090980.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073946.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073946.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA86" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA86" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA86" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pheromone binding", "id": "GO:0005550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005550", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA86" } ], "pmid": "" }, { "name": "pheromone receptor activity", "id": "GO:0016503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016503", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RA86", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RA86-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 288, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RA86-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RA86" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAD5-1", "uniprot_ac": "A0A5G2RAD5", "uniprot_id": "A0A5G2RAD5_PIG", "mass": { "chemical_mass": 46114.0, "monoisotopic_mass": 46114.0 }, "refseq": {}, "gene_names": [ { "name": "FOXD4", "type": "recommended", "evidence": [ { "id": "A0A5G2RAD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5" } ] } ], "protein_names": [ { "name": "Forkhead box protein L2", "type": "recommended", "evidence": [ { "id": "A0A5G2RAD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FOXD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5", "locus": {} } ], "crossref": [ { "id": "A0A5G2RAD5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041279", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041279", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20048", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20048", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11829:SF361", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11829:SF361", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RAD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLPSTEPLRSTPPRSLRSSDGEDGEIDILGEEEDEDEEEEEENDEPERSQRLLEQLHQPEPQGARRGAGALPRDRPESGCCPSDSSEFRTSTGSAAASADGTQPTKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHHQPPVAHLHHPFPLPAASAALHGPYTGMLLGPPTPSQPVLGAYSAPTSASRPCALLHPHPLRYLLLSAPAYAESPRKAEGEDLMTPGTLSALQPTLDSQPWEEGKGPASQSGGRCTSFSIESIMQGVRGATAAPLLHVSAAAASAARTILQQQQQQQDCASGCAPSKGALLGRHLSATAALLACQPGAEGPRFRSLVALSGREGTSSSSAECVCPLCLPEIDV", "length": 429, "header": "tr|A0A5G2RAD5-1|A0A5G2RAD5_PIG Isoform 1 of Forkhead box protein L2 OS=Sus scrofa OX=9823 GN=FOXD4 PE=4 SV=1 CANONICAL=A0A5G2RAD5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5/entry#A0A5G2RAD5-1", "sequence": { "sequence": "MNLPSTEPLRSTPPRSLRSSDGEDGEIDILGEEEDEDEEEEEENDEPERSQRLLEQLHQPEPQGARRGAGALPRDRPESGCCPSDSSEFRTSTGSAAASADGTQPTKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHHQPPVAHLHHPFPLPAASAALHGPYTGMLLGPPTPSQPVLGAYSAPTSASRPCALLHPHPLRYLLLSAPAYAESPRKAEGEDLMTPGTLSALQPTLDSQPWEEGKGPASQSGGRCTSFSIESIMQGVRGATAAPLLHVSAAAASAARTILQQQQQQQDCASGCAPSKGALLGRHLSATAALLACQPGAEGPRFRSLVALSGREGTSSSSAECVCPLCLPEIDV", "length": 429, "header": "tr|A0A5G2RAD5-1|A0A5G2RAD5_PIG Isoform 1 of Forkhead box protein L2 OS=Sus scrofa OX=9823 GN=FOXD4 PE=4 SV=1 CANONICAL=A0A5G2RAD5-1" }, "locus": { "chromosome": "1", "start_pos": 221579908, "end_pos": 221578077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077105.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077105.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073284.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073284.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 240, "start_aa": "Thr", "end_pos": 240, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr240", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAD5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 429, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAD5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAD5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD5" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 107, "end_pos": 201, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 240 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 193, "end_pos": 195 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAD9-1", "uniprot_ac": "A0A5G2RAD9", "uniprot_id": "A0A5G2RAD9_PIG", "mass": { "chemical_mass": 35249.0, "monoisotopic_mass": 35249.0 }, "refseq": { "ac": "XP_003132768", "name": "olfactory receptor 5K3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132768" }, "gene_names": [ { "name": "LOC100513311", "type": "recommended", "evidence": [ { "id": "A0A5G2RAD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9" } ] }, { "name": "LOC100513311", "type": "synonym", "evidence": [ { "id": "XP_003132768", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132768" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RAD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5K3-like", "type": "synonym", "evidence": [ { "id": "XP_003132768", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132768" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100513311", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9", "locus": {} } ], "crossref": [ { "id": "A0A5G2RAD9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAD9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100513311", "url": "https://www.ncbi.nlm.nih.gov/gene/100513311", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513311", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513311", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RAD9", "url": "https://www.orthodb.org/?gene=A0A5G2RAD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003132768", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132768", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RAD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGNNQSLTTEFTLTGFTDHPDLRTILFLVFLTIYLITMVGNLGLVALIFIERRLHTPMYIFLGNLALMDSCCSSSITPKMLQNFFSKDSIISLYECMAQFYFLCLAESADCFLLAAMAYDRYVAICNPLQYHTRMSKKLCIQMTTGAYLAGNLHSVIHVGLLFRLTFCGSHQINHFFCDVLPLYRLSCVDPYINELMILILAGFIQIFTITTVIISYLFILFIIFTMKSNKGRRKALSTCASHFLSVSIFYGSLIFMYVRPNSVKEEEKEKPVAVFYTIVIPLLNPFIYSLRNKEVMTVMKKMMKIS", "length": 308, "header": "tr|A0A5G2RAD9-1|A0A5G2RAD9_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100513311 PE=3 SV=1 CANONICAL=A0A5G2RAD9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9/entry#A0A5G2RAD9-1", "sequence": { "sequence": "MTGNNQSLTTEFTLTGFTDHPDLRTILFLVFLTIYLITMVGNLGLVALIFIERRLHTPMYIFLGNLALMDSCCSSSITPKMLQNFFSKDSIISLYECMAQFYFLCLAESADCFLLAAMAYDRYVAICNPLQYHTRMSKKLCIQMTTGAYLAGNLHSVIHVGLLFRLTFCGSHQINHFFCDVLPLYRLSCVDPYINELMILILAGFIQIFTITTVIISYLFILFIIFTMKSNKGRRKALSTCASHFLSVSIFYGSLIFMYVRPNSVKEEEKEKPVAVFYTIVIPLLNPFIYSLRNKEVMTVMKKMMKIS", "length": 308, "header": "tr|A0A5G2RAD9-1|A0A5G2RAD9_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100513311 PE=3 SV=1 CANONICAL=A0A5G2RAD9-1" }, "locus": { "chromosome": "13", "start_pos": 160969819, "end_pos": 160968896, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074531.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074531.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073997.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073997.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513311", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513311", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAD9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAD9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 308, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAD9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAD9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAD9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAF6-1", "uniprot_ac": "A0A5G2RAF6", "uniprot_id": "A0A5G2RAF6_PIG", "mass": { "chemical_mass": 19052.0, "monoisotopic_mass": 19052.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RAF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAF6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAF6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAF6", "locus": {} } ], "crossref": [ { "id": "A0A5G2RAF6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000043049", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000043049", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19414", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19414", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11430", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11430", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11430:SF129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11430:SF129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RAF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVLFLTIALGLVSALFFPVETPDITGTLYVKATVTDKDLSKEWRPSKVSPVTVTALDGGDLEVTFTFMKKGQCHEKGTVIQPTEEPGKYSAYGGKRHVYILELPVKDHYVFYCEGHVHGKQLHVGKLMGRNPEVNPEALEAFKRFAQRKGLSEDDISIPTQTEGCRPENN", "length": 171, "header": "tr|A0A5G2RAF6-1|A0A5G2RAF6_PIG Isoform 1 of Lipocalin/cytosolic fatty-acid binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RAF6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAF6/entry#A0A5G2RAF6-1", "sequence": { "sequence": "MKVLFLTIALGLVSALFFPVETPDITGTLYVKATVTDKDLSKEWRPSKVSPVTVTALDGGDLEVTFTFMKKGQCHEKGTVIQPTEEPGKYSAYGGKRHVYILELPVKDHYVFYCEGHVHGKQLHVGKLMGRNPEVNPEALEAFKRFAQRKGLSEDDISIPTQTEGCRPENN", "length": 171, "header": "tr|A0A5G2RAF6-1|A0A5G2RAF6_PIG Isoform 1 of Lipocalin/cytosolic fatty-acid binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RAF6-1" }, "locus": { "chromosome": "1", "start_pos": 272863506, "end_pos": 272860959, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081842.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081842.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074304.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074304.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAF6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAF6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small molecule binding", "id": "GO:0036094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036094", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAF6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 171, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAF6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAF6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAF6" }, { "id": "PF00061", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipocalin/cytosolic fatty-acid binding", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 164, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAG2-1", "uniprot_ac": "A0A5G2RAG2", "uniprot_id": "A0A5G2RAG2_PIG", "mass": { "chemical_mass": 18488.0, "monoisotopic_mass": 18488.0 }, "refseq": {}, "gene_names": [ { "name": "DSTN", "type": "recommended", "evidence": [ { "id": "A0A5G2RAG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2" } ] } ], "protein_names": [ { "name": "Destrin, actin depolymerizing factor", "type": "synonym", "evidence": [ { "id": "A0A5G2RAG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DSTN", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2", "locus": { "chromosome": "17", "start_pos": 26050353, "end_pos": 26043079, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007085", "url": "https://www.ensembl.org/id/ENSSSCG00000007085" } ] } } ], "crossref": [ { "id": "A0A5G2RAG2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000007085", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007085", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11286", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11286", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11913", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11913", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RAG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A900P1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A900P1Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A900P1Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A900P1Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "IASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV", "length": 165, "header": "tr|A0A5G2RAG2-1|A0A5G2RAG2_PIG Isoform 1 of Destrin, actin depolymerizing factor OS=Sus scrofa OX=9823 GN=DSTN PE=3 SV=2 CANONICAL=A0A5G2RAG2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2/entry#A0A5G2RAG2-1", "sequence": { "sequence": "IASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV", "length": 165, "header": "tr|A0A5G2RAG2-1|A0A5G2RAG2_PIG Isoform 1 of Destrin, actin depolymerizing factor OS=Sus scrofa OX=9823 GN=DSTN PE=3 SV=2 CANONICAL=A0A5G2RAG2-1" }, "locus": { "chromosome": "17", "start_pos": 26049235, "end_pos": 26043079, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074413.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074413.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074017.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074017.2" } ] } }, { "isoform_ac": "A0A900P1Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2/entry#A0A900P1Z5-1", "sequence": { "sequence": "QDPRVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV", "length": 165, "header": "tr|A0A900P1Z5-1|A0A5G2RAG2_PIG Computationally mapped isoform of Destrin, actin depolymerizing factor OS=Sus scrofa OX=9823 GN=DSTN PE=3 SV=1 CANONICAL=A0A5G2RAG2-1" }, "locus": { "chromosome": "17", "start_pos": 26049235, "end_pos": 26043088, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007757.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007757.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007548.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007548.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A900P1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A900P1Z5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "actin filament severing", "id": "GO:0051014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051014", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2" } ], "pmid": "" }, { "name": "actin filament fragmentation", "id": "GO:0030043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030043", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAG2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 165, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAG2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAG2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG2" }, { "id": "PS51263", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51263" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ADF-H", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 153, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAK4-1", "uniprot_ac": "A0A5G2RAK4", "uniprot_id": "A0A5G2RAK4_PIG", "mass": { "chemical_mass": 13949.0, "monoisotopic_mass": 13949.0 }, "refseq": {}, "gene_names": [ { "name": "MRPS6", "type": "recommended", "evidence": [ { "id": "A0A5G2RAK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein bS6m", "type": "recommended", "evidence": [ { "id": "A0A5G2RAK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4/entry#names_and_taxonomy" } ] }, { "name": "28S ribosomal protein S6, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A5G2RAK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MRPS6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4", "locus": { "chromosome": "13", "start_pos": 197756785, "end_pos": 197738890, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026981", "url": "https://www.ensembl.org/id/ENSSSCG00000026981" } ] } } ], "crossref": [ { "id": "A0A5G2RAK4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026981", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026981", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15465", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15465", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21011", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21011", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21011:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21011:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RAK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QPLFPLALCGFGEMPETAAALKRTLEALMDRGAVVRNLENLGERMLPYKISAHNQRHSRGGYFLVDFYAPATTVESMMEHLSRDIDVIRPNIVKHPLTQEVKECEGIVPVPLEEKLYSTKKRK", "length": 123, "header": "tr|A0A5G2RAK4-1|A0A5G2RAK4_PIG Isoform 1 of Small ribosomal subunit protein bS6m OS=Sus scrofa OX=9823 GN=MRPS6 PE=3 SV=1 CANONICAL=A0A5G2RAK4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4/entry#A0A5G2RAK4-1", "sequence": { "sequence": "QPLFPLALCGFGEMPETAAALKRTLEALMDRGAVVRNLENLGERMLPYKISAHNQRHSRGGYFLVDFYAPATTVESMMEHLSRDIDVIRPNIVKHPLTQEVKECEGIVPVPLEEKLYSTKKRK", "length": 123, "header": "tr|A0A5G2RAK4-1|A0A5G2RAK4_PIG Isoform 1 of Small ribosomal subunit protein bS6m OS=Sus scrofa OX=9823 GN=MRPS6 PE=3 SV=1 CANONICAL=A0A5G2RAK4-1" }, "locus": { "chromosome": "13", "start_pos": 197756393, "end_pos": 197738890, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080201.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080201.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074354.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074354.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-SSC-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-SSC-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial small ribosomal subunit", "id": "GO:0005763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4" } ], "pmid": "" }, { "name": "small ribosomal subunit rRNA binding", "id": "GO:0070181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070181", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAK4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAK4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 123, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAK4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAK4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAL2-1", "uniprot_ac": "A0A5G2RAL2", "uniprot_id": "A0A5G2RAL2_PIG", "mass": { "chemical_mass": 34148.0, "monoisotopic_mass": 34148.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Potassium channel domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAL2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAL2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAL2", "locus": {} } ], "crossref": [ { "id": "A0A5G2RAL2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAL2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000050857", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000050857", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003:SF315", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003:SF315", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RAL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEDLWSLDFFLIELVASQVSRYVLLIGFMSYCLMGAKVFQTLETDIQEKLKNSFLDAETALMKNYVNITPEELEIFLQMLALSIKHGIIPVRTGVVYFSWSFRNSFSFVASTLSTIGYGSIAPRTPMGQIFCVFYALLGIPLTIIFLKAVSNAILRPLSGFEKYLQNMGMEERRIRIYTILFFLVTGLSLFILLPPLLFMHTEGWTYREGLYFAFISLSTIGFGDYVIGINPSQNYSHIYMAIIMLWCAFGLTWIALLFDLFAKTLEKTKTKLTCHKLCQTERKSSGKSSYIWPFFA", "length": 298, "header": "tr|A0A5G2RAL2-1|A0A5G2RAL2_PIG Isoform 1 of Potassium channel domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RAL2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAL2/entry#A0A5G2RAL2-1", "sequence": { "sequence": "MEEDLWSLDFFLIELVASQVSRYVLLIGFMSYCLMGAKVFQTLETDIQEKLKNSFLDAETALMKNYVNITPEELEIFLQMLALSIKHGIIPVRTGVVYFSWSFRNSFSFVASTLSTIGYGSIAPRTPMGQIFCVFYALLGIPLTIIFLKAVSNAILRPLSGFEKYLQNMGMEERRIRIYTILFFLVTGLSLFILLPPLLFMHTEGWTYREGLYFAFISLSTIGFGDYVIGINPSQNYSHIYMAIIMLWCAFGLTWIALLFDLFAKTLEKTKTKLTCHKLCQTERKSSGKSSYIWPFFA", "length": 298, "header": "tr|A0A5G2RAL2-1|A0A5G2RAL2_PIG Isoform 1 of Potassium channel domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RAL2-1" }, "locus": { "chromosome": "1", "start_pos": 188215655, "end_pos": 188193009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070707.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070707.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073370.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073370.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAL2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015271", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAL2" } ], "pmid": "" }, { "name": "potassium ion leak channel activity", "id": "GO:0022841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022841", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAL2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAL2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAL2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 298, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAL2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAL2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAL2" }, { "id": "PF07885", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 155, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 }, { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAM5-1", "uniprot_ac": "A0A5G2RAM5", "uniprot_id": "A0A5G2RAM5_PIG", "mass": { "chemical_mass": 60340.0, "monoisotopic_mass": 60340.0 }, "refseq": {}, "gene_names": [ { "name": "SPG11", "type": "recommended", "evidence": [ { "id": "A0A5G2RAM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5" } ] }, { "name": "PATL2", "type": "synonym", "evidence": [ { "id": "A0A5G2RAM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5" } ] } ], "protein_names": [ { "name": "PAT1 homolog 2", "type": "synonym", "evidence": [ { "id": "A0A5G2RAM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SPG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5", "locus": { "chromosome": "1", "start_pos": 127003397, "end_pos": 126902186, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004684", "url": "https://www.ensembl.org/id/ENSSSCG00000004684" } ] } } ], "crossref": [ { "id": "A0A5G2RAM5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004684", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004684", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR019167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21551", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21551", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21551:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21551:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RAM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKYLQGPGRAYGPLALEVELVSASHLEKEEPNEDEKKEEKQDPDLASDLEEEENDLGDPAVLSAVHNTQKGLLSSPGIKASGVLGMSPASLHFQWQTPDYLVPLPFQPAFPSASSPTKYFGPPLPSPDPPLLGSPSTSWPLRLSHLTQLHPQHQRILKQQQSSQPPSSPAKEPWSQQPDPYANLMSQKEKDWVVKVQMVQLQSENPRLDDYYYQEYYQKLEKKQAEEERFGRKTKVESLKLVTPYIQKAETYESVVRIKGSLGQVAVSTCFSPRRAIDAVPHGTQEQETGAAGSQRLQVLYRIEKMFLQLLEIEEGQKDVTSQPCDPEQQSNQAEKLFQALKTHEQNDLEEAADGFLQVLSIRKGKALVARLLPFLPQDRAVSLLLTITRHLPFLVRRDVADQALQLLFNPLSKCISHLTFQELLQGLQGLMELPPGCSERPVTVVLQNQFGISLLYTLLSHGEQLVSLDSSLEEPNSGRTAWTDMVVLTAWEIAQMPTASLAEPLAFSSNLLPLFCHHVDKQLVQQLEARMKFALTY", "length": 538, "header": "tr|A0A5G2RAM5-1|A0A5G2RAM5_PIG Isoform 1 of PAT1 homolog 2 OS=Sus scrofa OX=9823 GN=SPG11 PE=3 SV=1 CANONICAL=A0A5G2RAM5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5/entry#A0A5G2RAM5-1", "sequence": { "sequence": "MKYLQGPGRAYGPLALEVELVSASHLEKEEPNEDEKKEEKQDPDLASDLEEEENDLGDPAVLSAVHNTQKGLLSSPGIKASGVLGMSPASLHFQWQTPDYLVPLPFQPAFPSASSPTKYFGPPLPSPDPPLLGSPSTSWPLRLSHLTQLHPQHQRILKQQQSSQPPSSPAKEPWSQQPDPYANLMSQKEKDWVVKVQMVQLQSENPRLDDYYYQEYYQKLEKKQAEEERFGRKTKVESLKLVTPYIQKAETYESVVRIKGSLGQVAVSTCFSPRRAIDAVPHGTQEQETGAAGSQRLQVLYRIEKMFLQLLEIEEGQKDVTSQPCDPEQQSNQAEKLFQALKTHEQNDLEEAADGFLQVLSIRKGKALVARLLPFLPQDRAVSLLLTITRHLPFLVRRDVADQALQLLFNPLSKCISHLTFQELLQGLQGLMELPPGCSERPVTVVLQNQFGISLLYTLLSHGEQLVSLDSSLEEPNSGRTAWTDMVVLTAWEIAQMPTASLAEPLAFSSNLLPLFCHHVDKQLVQQLEARMKFALTY", "length": 538, "header": "tr|A0A5G2RAM5-1|A0A5G2RAM5_PIG Isoform 1 of PAT1 homolog 2 OS=Sus scrofa OX=9823 GN=SPG11 PE=3 SV=1 CANONICAL=A0A5G2RAM5-1" }, "locus": { "chromosome": "1", "start_pos": 126899406, "end_pos": 126890892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052986.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052986.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074379.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074379.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "deadenylation-dependent decapping of nuclear-transcribed mRNA", "id": "GO:0000290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000290", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5" } ], "pmid": "" }, { "name": "P-body assembly", "id": "GO:0033962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033962", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAM5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 538, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAM5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAM5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAM5" }, { "id": "PF09770", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09770" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "mRNA decay factor PAT1", "eco_id": "ECO_0000259", "start_pos": 258, "end_pos": 395, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAP0-1", "uniprot_ac": "A0A5G2RAP0", "uniprot_id": "A0A5G2RAP0_PIG", "mass": { "chemical_mass": 45723.0, "monoisotopic_mass": 45723.0 }, "refseq": {}, "gene_names": [ { "name": "ASB4", "type": "recommended", "evidence": [ { "id": "A0A5G2RAP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and SOCS box containing 4", "type": "synonym", "evidence": [ { "id": "A0A5G2RAP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ASB4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0", "locus": { "chromosome": "9", "start_pos": 75203447, "end_pos": 75018067, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015333", "url": "https://www.ensembl.org/id/ENSSSCG00000015333" } ] } } ], "crossref": [ { "id": "A0A5G2RAP0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015333", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015333", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03723", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03723", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RAP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0WEM2", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WEM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0WEM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WEM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWGPNLLPGAIELLQIPIAPQQKLSYFFFHFLASYKQGYWLPSYKLKSSWATGLHLSVLFGHVECLLVLLDHNATINCRPNGKTPLHVACEMANLDCVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVWRGANVNMKTNNQDEETPLHTAAHFGLAELVAFYVEHGAIVDSVNAHMETPLAIATYWALRFKEQEYSREHHLICRMLLDYKAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLVDINGCAAIQYVLKVTSVRPAAQPEICYQLLLNHGAARIYPPQFHKVIQACHSCPKAIEVVVNAYEHIRWNVKWKRAIPDDDLEKYWDFYHSLFTVCSNSPRTLMHLSRCAIRRTLHSRCHRVIPLLSLPLSLKKYLLLEPEGIIY", "length": 402, "header": "tr|A0A5G2RAP0-1|A0A5G2RAP0_PIG Isoform 1 of Ankyrin repeat and SOCS box containing 4 OS=Sus scrofa OX=9823 GN=ASB4 PE=4 SV=2 CANONICAL=A0A5G2RAP0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0/entry#A0A5G2RAP0-1", "sequence": { "sequence": "MSWGPNLLPGAIELLQIPIAPQQKLSYFFFHFLASYKQGYWLPSYKLKSSWATGLHLSVLFGHVECLLVLLDHNATINCRPNGKTPLHVACEMANLDCVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVWRGANVNMKTNNQDEETPLHTAAHFGLAELVAFYVEHGAIVDSVNAHMETPLAIATYWALRFKEQEYSREHHLICRMLLDYKAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLVDINGCAAIQYVLKVTSVRPAAQPEICYQLLLNHGAARIYPPQFHKVIQACHSCPKAIEVVVNAYEHIRWNVKWKRAIPDDDLEKYWDFYHSLFTVCSNSPRTLMHLSRCAIRRTLHSRCHRVIPLLSLPLSLKKYLLLEPEGIIY", "length": 402, "header": "tr|A0A5G2RAP0-1|A0A5G2RAP0_PIG Isoform 1 of Ankyrin repeat and SOCS box containing 4 OS=Sus scrofa OX=9823 GN=ASB4 PE=4 SV=2 CANONICAL=A0A5G2RAP0-1" }, "locus": { "chromosome": "9", "start_pos": 75201414, "end_pos": 75083545, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082235.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082235.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074082.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074082.2" } ] } }, { "isoform_ac": "A0A8D0WEM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0/entry#A0A8D0WEM2-1", "sequence": { "sequence": "MDGPAAPVTKSATAKLVKRNFLEALKSNDFGKLKAILIQRQIDVDTVFEVEDENMVLASYKQGYWLPSYKLKSSWATGLHLSVLFGHVECLLVLLDHNATINCRPNGKTPLHVACEMANLDCVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVWRGANVNMKTNNQDEETPLHTAAHFGLAELVAFYVEHGAIVDSVNAHMETPLAIATYWALRFKEQEYSREHHLICRMLLDYKAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLVDINGCAAIQYVLKVTSVRPAAQPEICYQLLLNHGAARIYPPQFHKVRLCPVVSRIMETQMVAQSELSK", "length": 349, "header": "tr|A0A8D0WEM2-1|A0A5G2RAP0_PIG Computationally mapped isoform of Ankyrin repeat and SOCS box containing 4 OS=Sus scrofa OX=9823 GN=ASB4 PE=4 SV=1 CANONICAL=A0A5G2RAP0-1" }, "locus": { "chromosome": "9", "start_pos": 75181729, "end_pos": 75110482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082008.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082008.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061077.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061077.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0WEM2", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WEM2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0" } ], "pmid": "" }, { "name": "positive regulation of vasculogenesis", "id": "GO:2001214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001214", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Cul2-RING ubiquitin ligase complex", "id": "GO:0031462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031462", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0" } ], "pmid": "" }, { "name": "Cul5-RING ubiquitin ligase complex", "id": "GO:0031466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031466", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAP0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAP0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAP0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP0" }, { "id": "PS50225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SOCS box", "eco_id": "ECO_0000259", "start_pos": 355, "end_pos": 393, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAP4-1", "uniprot_ac": "A0A5G2RAP4", "uniprot_id": "A0A5G2RAP4_PIG", "mass": { "chemical_mass": 26493.0, "monoisotopic_mass": 26493.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Claudin", "type": "recommended", "evidence": [ { "id": "A0A5G2RAP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP4", "locus": {} } ], "crossref": [ { "id": "A0A5G2RAP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000042673", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042673", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RAP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDGGPEIHGKCSLPSGPSFAPDAPSSGDGSPGSASTSPLFNGRLKLQLMGFVVATVGWVLGTTSMALAEWRVWYVNSTSLLSSHLACVGVWRACIFRHGNGLDRAIGCQGYSYFDPYVPMDIHVAQILLPLATVLGLFSKAAIIFALKNMYLSKVQKTCDASAVAGMLSIAASFCILAAVVWNQLSIQTEEGIAFPPSFNLPFKPDSQEVGGAALMAFLGSCGLFFGGLAYFSYKYPLDSRVHPTTSDT", "length": 250, "header": "tr|A0A5G2RAP4-1|A0A5G2RAP4_PIG Isoform 1 of Claudin OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RAP4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP4/entry#A0A5G2RAP4-1", "sequence": { "sequence": "MSDGGPEIHGKCSLPSGPSFAPDAPSSGDGSPGSASTSPLFNGRLKLQLMGFVVATVGWVLGTTSMALAEWRVWYVNSTSLLSSHLACVGVWRACIFRHGNGLDRAIGCQGYSYFDPYVPMDIHVAQILLPLATVLGLFSKAAIIFALKNMYLSKVQKTCDASAVAGMLSIAASFCILAAVVWNQLSIQTEEGIAFPPSFNLPFKPDSQEVGGAALMAFLGSCGLFFGGLAYFSYKYPLDSRVHPTTSDT", "length": 250, "header": "tr|A0A5G2RAP4-1|A0A5G2RAP4_PIG Isoform 1 of Claudin OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RAP4-1" }, "locus": { "chromosome": "X", "start_pos": 6493179, "end_pos": 6489952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074400.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074400.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067678.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067678.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP4" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAP4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 250, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAP4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAP4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAS0-1", "uniprot_ac": "A0A5G2RAS0", "uniprot_id": "A0A5G2RAS0_PIG", "mass": { "chemical_mass": 35394.0, "monoisotopic_mass": 35394.0 }, "refseq": { "ac": "XP_020937089", "name": "olfactory receptor 4S2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937089" }, "gene_names": [ { "name": "LOC110258241", "type": "recommended", "evidence": [ { "id": "A0A5G2RAS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0" } ] }, { "name": "LOC110258241", "type": "synonym", "evidence": [ { "id": "XP_020937089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937089" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RAS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4S2-like", "type": "synonym", "evidence": [ { "id": "XP_020937089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937089" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110258241", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0", "locus": {} } ], "crossref": [ { "id": "A0A5G2RAS0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110258241", "url": "https://www.ncbi.nlm.nih.gov/gene/110258241", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110258241", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258241", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RAS0", "url": "https://www.orthodb.org/?gene=A0A5G2RAS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020937089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937089", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RAS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEISNVTEFVFWGLSQNLKVEKVCLVVFSFFYSVILLGNLLIMLTVYVGNLSKSPMYFFLSYLSFVDICYSSAIAPRMMVDLLAKTKTISYVGCMLQLFVAHFLGCTEIFILTVMAYDRYVAICKPLHYMTIMDRERCNKMLLGTWLGGFLHSIVQVALVVQLPFCGPNEIDHYFCDIHPLLKLACTDTYVVGVVVIANSGIITLVSFVILLFSYILILVFLRKQSAEGRRKALSTCGSHIAVVIIFFGPCTFMYMRPETTFSEDKMVAVFYTIITPMLNPLIYTLRNAQVKNAMKKLWGRWVFWGAKGK", "length": 311, "header": "tr|A0A5G2RAS0-1|A0A5G2RAS0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258241 PE=3 SV=1 CANONICAL=A0A5G2RAS0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0/entry#A0A5G2RAS0-1", "sequence": { "sequence": "MEEISNVTEFVFWGLSQNLKVEKVCLVVFSFFYSVILLGNLLIMLTVYVGNLSKSPMYFFLSYLSFVDICYSSAIAPRMMVDLLAKTKTISYVGCMLQLFVAHFLGCTEIFILTVMAYDRYVAICKPLHYMTIMDRERCNKMLLGTWLGGFLHSIVQVALVVQLPFCGPNEIDHYFCDIHPLLKLACTDTYVVGVVVIANSGIITLVSFVILLFSYILILVFLRKQSAEGRRKALSTCGSHIAVVIIFFGPCTFMYMRPETTFSEDKMVAVFYTIITPMLNPLIYTLRNAQVKNAMKKLWGRWVFWGAKGK", "length": 311, "header": "tr|A0A5G2RAS0-1|A0A5G2RAS0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258241 PE=3 SV=1 CANONICAL=A0A5G2RAS0-1" }, "locus": { "chromosome": "AEMK02000493.1", "start_pos": 145223, "end_pos": 144291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077212.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077212.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073430.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073430.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110258241", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258241", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAS0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAS0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAS0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 51, "end_pos": 53 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RAS4-1", "uniprot_ac": "A0A5G2RAS4", "uniprot_id": "A0A5G2RAS4_PIG", "mass": { "chemical_mass": 28678.0, "monoisotopic_mass": 28678.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RAS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4", "locus": {} } ], "crossref": [ { "id": "A0A5G2RAS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RAS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYFFLTHLALTDVSFSSVTVPKMLVNMQTQNRSIPYAGCVTQMYFFIFFTDLDSFLIASMAYDRYVAICHPLHYTSIMREELCAFLVAVSWFLSGASSLSHTLLLTQLSFCADIIPHFFCDLGALLRLSCSDIFLNELVMFTAGVVVITLPFICILVSYGYIGATILRIPSTKGIYKAFSTCGSHLSVVSLYYGSIFGQYLFPTLGNFIDKDIIVALMYTVVTPMLNPFIYSLRNRDIKEAFEKLFSRATFFLP", "length": 254, "header": "tr|A0A5G2RAS4-1|A0A5G2RAS4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RAS4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4/entry#A0A5G2RAS4-1", "sequence": { "sequence": "MYFFLTHLALTDVSFSSVTVPKMLVNMQTQNRSIPYAGCVTQMYFFIFFTDLDSFLIASMAYDRYVAICHPLHYTSIMREELCAFLVAVSWFLSGASSLSHTLLLTQLSFCADIIPHFFCDLGALLRLSCSDIFLNELVMFTAGVVVITLPFICILVSYGYIGATILRIPSTKGIYKAFSTCGSHLSVVSLYYGSIFGQYLFPTLGNFIDKDIIVALMYTVVTPMLNPFIYSLRNRDIKEAFEKLFSRATFFLP", "length": 254, "header": "tr|A0A5G2RAS4-1|A0A5G2RAS4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RAS4-1" }, "locus": { "chromosome": "AEMK02000598.1", "start_pos": 570793, "end_pos": 570032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042202.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042202.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073435.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073435.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RAS4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 254, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RAS4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RAS4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RAS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAS4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 231, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RB27-1", "uniprot_ac": "A0A5G2RB27", "uniprot_id": "A0A5G2RB27_PIG", "mass": { "chemical_mass": 37538.0, "monoisotopic_mass": 37538.0 }, "refseq": { "ac": "XP_005669676", "name": "probable G-protein coupled receptor 62", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669676" }, "gene_names": [ { "name": "GPR62", "type": "recommended", "evidence": [ { "id": "A0A5G2RB27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" } ] }, { "name": "GPR62", "type": "synonym", "evidence": [ { "id": "XP_005669676", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669676" } ] } ], "protein_names": [ { "name": "G-protein coupled receptor 62", "type": "recommended", "evidence": [ { "id": "A0A5G2RB27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27/entry#names_and_taxonomy" } ] }, { "name": "probable G-protein coupled receptor 62", "type": "synonym", "evidence": [ { "id": "XP_005669676", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669676" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GPR62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27", "locus": { "chromosome": "13", "start_pos": 34089289, "end_pos": 34088198, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000048899", "url": "https://www.ensembl.org/id/ENSSSCG00000048899" } ] } } ], "crossref": [ { "id": "A0A5G2RB27", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RB27", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000048899", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000048899", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100625569", "url": "https://www.ncbi.nlm.nih.gov/gene/100625569", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100625569", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625569", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RB27", "url": "https://www.orthodb.org/?gene=A0A5G2RB27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22752", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22752", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22752:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22752:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005669676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669676", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RB27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RB27-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANATGLNAPEVAATIALILASVVEAATLLGNGALLVVVLRTPGLRDALYLVHLCIVDLLAAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGARPPPTLVLTAVWAAAGLLGALSLLGPPPAPPPAPARCSVLAGGLGPFRPLWAVLAFALPALLLLGAYGGIFLVARRAALRPPRPARGSRPRSDSLDSRLSILPPLRPRLPWGKAALAPTLAVGQFAACWLPYGCACLAPAARAAAAEAAVTWVAYSAFAAHPFLYGLLQRPVRRTLGRLARRALPQPPRACTSRAWHPRALLQHLQGPPEGPALGPSEAREQARDLAGEESLSMPEAT", "length": 363, "header": "tr|A0A5G2RB27-1|A0A5G2RB27_PIG Isoform 1 of G-protein coupled receptor 62 OS=Sus scrofa OX=9823 GN=GPR62 PE=4 SV=1 CANONICAL=A0A5G2RB27-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RB27-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27/entry#A0A5G2RB27-1", "sequence": { "sequence": "MANATGLNAPEVAATIALILASVVEAATLLGNGALLVVVLRTPGLRDALYLVHLCIVDLLAAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHPLRPGARPPPTLVLTAVWAAAGLLGALSLLGPPPAPPPAPARCSVLAGGLGPFRPLWAVLAFALPALLLLGAYGGIFLVARRAALRPPRPARGSRPRSDSLDSRLSILPPLRPRLPWGKAALAPTLAVGQFAACWLPYGCACLAPAARAAAAEAAVTWVAYSAFAAHPFLYGLLQRPVRRTLGRLARRALPQPPRACTSRAWHPRALLQHLQGPPEGPALGPSEAREQARDLAGEESLSMPEAT", "length": 363, "header": "tr|A0A5G2RB27-1|A0A5G2RB27_PIG Isoform 1 of G-protein coupled receptor 62 OS=Sus scrofa OX=9823 GN=GPR62 PE=4 SV=1 CANONICAL=A0A5G2RB27-1" }, "locus": { "chromosome": "13", "start_pos": 34089286, "end_pos": 34088198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066490.1", "url": "https://www.ensembl.org/id/ENSSSCT00000066490.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067808.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067808.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100625569", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625569", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" } ], "pmid": "" }, { "name": "arrestin family protein binding", "id": "GO:1990763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990763", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of calcium-mediated signaling", "id": "GO:0050850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050850", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" } ], "pmid": "" }, { "name": "ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0038035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038035", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RB27-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 363, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RB27-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RB27" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RB27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB27" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RB96-1", "uniprot_ac": "A0A5G2RB96", "uniprot_id": "A0A5G2RB96_PIG", "mass": { "chemical_mass": 20009.0, "monoisotopic_mass": 20009.0 }, "refseq": {}, "gene_names": [ { "name": "IL20", "type": "recommended", "evidence": [ { "id": "A0A5G2RB96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96" } ] } ], "protein_names": [ { "name": "Interleukin family protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RB96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Immune regulatory cytokine.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96#function" }, { "database": "UniProtKB", "id": "RU368043", "url": "https://www.uniprot.org/uniprotkb/RU368043#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IL20", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96", "locus": { "chromosome": "9", "start_pos": 67502096, "end_pos": 67498813, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015654", "url": "https://www.ensembl.org/id/ENSSSCG00000015654" } ] } } ], "crossref": [ { "id": "A0A5G2RB96", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RB96", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015654", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015654", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48482", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48482", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48482:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48482:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00726", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00726", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8854691", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854691", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RB96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RB96-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SEZ1", "url": "https://www.uniprot.org/uniprotkb/F1SEZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SEZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1SEZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRSGLPLCLLSAVFYLFWTPSAGLKTLLGSCVITANLQGIRNGFSEIRDSVQARDEIIDIRILKKTQSLQDTKPADQCCLLRHILRLYLDRVFKNYQTPDHHVLRKISRLANSFLTIKKDLRLCHARMTCSCGEEAMEKYGQIMSHFEELQPQAAVVKALGELDILLQWMEETV", "length": 175, "header": "tr|A0A5G2RB96-1|A0A5G2RB96_PIG Isoform 1 of Interleukin family protein OS=Sus scrofa OX=9823 GN=IL20 PE=3 SV=1 CANONICAL=A0A5G2RB96-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RB96-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96/entry#A0A5G2RB96-1", "sequence": { "sequence": "MNRSGLPLCLLSAVFYLFWTPSAGLKTLLGSCVITANLQGIRNGFSEIRDSVQARDEIIDIRILKKTQSLQDTKPADQCCLLRHILRLYLDRVFKNYQTPDHHVLRKISRLANSFLTIKKDLRLCHARMTCSCGEEAMEKYGQIMSHFEELQPQAAVVKALGELDILLQWMEETV", "length": 175, "header": "tr|A0A5G2RB96-1|A0A5G2RB96_PIG Isoform 1 of Interleukin family protein OS=Sus scrofa OX=9823 GN=IL20 PE=3 SV=1 CANONICAL=A0A5G2RB96-1" }, "locus": { "chromosome": "9", "start_pos": 67501561, "end_pos": 67498813, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083801.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083801.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071430.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071430.1" } ] } }, { "isoform_ac": "F1SEZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96/entry#F1SEZ1-1", "sequence": { "sequence": "MNRSGLPLCLLSAVFYLFWTPSAGLKTLLGSCVITANLQGIRNGFSEIRDSVQARDEIIDIRILKKTQSLQDTKPADQCCLLRHILRLYLDRVFKNYQTPDHHVLRKISRLANSFLTIKKDLRLCLQPQAAVVKALGELDILLQWMEETV", "length": 150, "header": "tr|F1SEZ1-1|A0A5G2RB96_PIG Computationally mapped isoform of Interleukin family protein OS=Sus scrofa OX=9823 GN=IL20 PE=3 SV=3 CANONICAL=A0A5G2RB96-1" }, "locus": { "chromosome": "9", "start_pos": 67501561, "end_pos": 67498813, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017051.3", "url": "https://www.ensembl.org/id/ENSSSCT00000017051.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016596.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016596.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SEZ1", "url": "https://www.uniprot.org/uniprotkb/F1SEZ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8854691", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854691", "resource": "Reactome", "description": "Interleukin-20 family signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "interleukin-20 receptor binding", "id": "GO:0045517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045517", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96" } ], "pmid": "" }, { "name": "interleukin-22 receptor binding", "id": "GO:0045518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045518", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96" } ], "pmid": "" }, { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RB96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RB96-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 175, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RB96-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RB96" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 2, "end_pos": 4 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RBD3-1", "uniprot_ac": "A0A5G2RBD3", "uniprot_id": "A0A5G2RBD3_PIG", "mass": { "chemical_mass": 48060.0, "monoisotopic_mass": 48060.0 }, "refseq": {}, "gene_names": [ { "name": "KRT18", "type": "recommended", "evidence": [ { "id": "A0A5G2RBD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ] } ], "protein_names": [ { "name": "Keratin 18", "type": "synonym", "evidence": [ { "id": "A0A5G2RBD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KRT18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3", "locus": { "chromosome": "5", "start_pos": 18221429, "end_pos": 18217691, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000253", "url": "https://www.ensembl.org/id/ENSSSCG00000000253" } ] } } ], "crossref": [ { "id": "A0A5G2RBD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000253", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000253", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFSTQSSFSSYRSVQSPGHRVRPVSSAASVYAGAGGSGSRISVSRSSSVRGGSGWGAGMAGGLVGVGGIQGEKETMQDLNDRLASYLERVRSLEADNRRLEIKIREHLEKKGPQVRDWSHYLKTIEELRAQIFASSVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRKVIDDTNVTRLQLETEIEALKEELLFMKKNHEEASRGRKTIKGLQNQIANSGLTVELDAPKPQDLSKIMADIRAQYDELAQKNREELDKYWSQQIEESTSVVTSQSAEIGAAEMTLTELRRTVQSLEIDLDSMRNLKATLENSLREVEARYALQMEQLNGVLLHLESELAQTRAEGQRQTQEYEALLNIKVKLEAEINTYRRLLEDGEDFNLGDALDSSNSRQTIQKTTTLRLVDGKVVSETSDTKVLRH", "length": 429, "header": "tr|A0A5G2RBD3-1|A0A5G2RBD3_PIG Isoform 1 of Keratin 18 OS=Sus scrofa OX=9823 GN=KRT18 PE=1 SV=2 CANONICAL=A0A5G2RBD3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RBD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3/entry#A0A5G2RBD3-1", "sequence": { "sequence": "MSFSTQSSFSSYRSVQSPGHRVRPVSSAASVYAGAGGSGSRISVSRSSSVRGGSGWGAGMAGGLVGVGGIQGEKETMQDLNDRLASYLERVRSLEADNRRLEIKIREHLEKKGPQVRDWSHYLKTIEELRAQIFASSVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRKVIDDTNVTRLQLETEIEALKEELLFMKKNHEEASRGRKTIKGLQNQIANSGLTVELDAPKPQDLSKIMADIRAQYDELAQKNREELDKYWSQQIEESTSVVTSQSAEIGAAEMTLTELRRTVQSLEIDLDSMRNLKATLENSLREVEARYALQMEQLNGVLLHLESELAQTRAEGQRQTQEYEALLNIKVKLEAEINTYRRLLEDGEDFNLGDALDSSNSRQTIQKTTTLRLVDGKVVSETSDTKVLRH", "length": 429, "header": "tr|A0A5G2RBD3-1|A0A5G2RBD3_PIG Isoform 1 of Keratin 18 OS=Sus scrofa OX=9823 GN=KRT18 PE=1 SV=2 CANONICAL=A0A5G2RBD3-1" }, "locus": { "chromosome": "5", "start_pos": 18221368, "end_pos": 18217790, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074447.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074447.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067918.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067918.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-SSC-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ], "pmid": "" }, { "name": "intermediate filament cytoskeleton organization", "id": "GO:0045104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045104", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ], "pmid": "" }, { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBD3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RBD3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 429, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RBD3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBD3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RBD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBD3" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 390, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RBJ3-1", "uniprot_ac": "A0A5G2RBJ3", "uniprot_id": "A0A5G2RBJ3_PIG", "mass": { "chemical_mass": 63639.0, "monoisotopic_mass": 63639.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Tyrosine-protein kinase receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RBJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3/entry#names_and_taxonomy" } ] }, { "name": "2.7.10.1", "type": "synonym", "evidence": [ { "id": "A0A5G2RBJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3", "locus": {} } ], "crossref": [ { "id": "A0A5G2RBJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044640", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044640", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05036", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05036", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24416:SF276", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416:SF276", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-201556", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9851151", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9851151", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RBJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEIQEGFLEEVVQPPCPGHLAADRRLSAVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPVEYGPLVEEEEKVPMRPKDPEGIPPLLVSQPRREEGPEPAAPPPPPAASSGKAGKKAAAAELAVRGPRGAAADGGHVNMAFAPSSAPSELHKVQGSRNKPTSLWNPTYGSWFTEKPTPKNSPPAKREPPGRGSLGREGSCGGPSAAAPGRLPGAALLLEPSSLTADVKDVPLFRLRHFPCGTVHYGYQQQGFPPEAAPGRSPDPALKGQAAP", "length": 581, "header": "tr|A0A5G2RBJ3-1|A0A5G2RBJ3_PIG Isoform 1 of Tyrosine-protein kinase receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RBJ3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RBJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3/entry#A0A5G2RBJ3-1", "sequence": { "sequence": "MEIQEGFLEEVVQPPCPGHLAADRRLSAVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPVEYGPLVEEEEKVPMRPKDPEGIPPLLVSQPRREEGPEPAAPPPPPAASSGKAGKKAAAAELAVRGPRGAAADGGHVNMAFAPSSAPSELHKVQGSRNKPTSLWNPTYGSWFTEKPTPKNSPPAKREPPGRGSLGREGSCGGPSAAAPGRLPGAALLLEPSSLTADVKDVPLFRLRHFPCGTVHYGYQQQGFPPEAAPGRSPDPALKGQAAP", "length": 581, "header": "tr|A0A5G2RBJ3-1|A0A5G2RBJ3_PIG Isoform 1 of Tyrosine-protein kinase receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RBJ3-1" }, "locus": { "chromosome": "3", "start_pos": 110102820, "end_pos": 110072602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090022.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090022.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067983.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067983.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-201556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201556", "resource": "Reactome", "description": "Signaling by ALK" }, { "id": "R-SSC-9851151", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9851151", "resource": "Reactome", "description": "MDK and PTN in ALK signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase activity", "id": "GO:0004714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004714", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3" } ], "pmid": "" }, { "name": "regulation of neuron differentiation", "id": "GO:0045664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045664", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "R-SSC-201486", "name": "ALK binds ligand pleiotrophin (PTN)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-201486", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201486" } ] }, { "id": "R-SSC-201510", "name": "PI3K synthesizes PIP3 downstream of ALK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-201510", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201510" } ] }, { "id": "R-SSC-201515", "name": "Active ALK recruits PI3K", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-201515", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201515" } ] }, { "id": "R-SSC-201521", "name": "ALK autophosphorylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-201521", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201521" } ] }, { "id": "R-SSC-9667914", "name": "ALK binds ligand midkine (MDK)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9667914", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9667914" } ] }, { "id": "R-SSC-9700149", "name": "Active ALK binds PLCG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9700149", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9700149" } ] }, { "id": "R-SSC-9700154", "name": "Active ALK binds SHC1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9700154", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9700154" } ] }, { "id": "R-SSC-9700156", "name": "Active ALK dimer binds IRS1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9700156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9700156" } ] }, { "id": "R-SSC-9700168", "name": "Active ALK phosphorylates IRS1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9700168", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9700168" } ] }, { "id": "R-SSC-9700171", "name": "Active ALK phosphorylates PLCG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9700171", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9700171" } ] }, { "id": "R-SSC-9700175", "name": "Active ALK phosphorylates SHC1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9700175", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9700175" } ] }, { "id": "R-SSC-9700200", "name": "PTPRZ dephosphorylates ligand-bound ALK dimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9700200", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9700200" } ] }, { "id": "R-SSC-9700662", "name": "Liganded-ALK dimer binds type I ALK-binding TKIs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9700662", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9700662" } ] }, { "id": "R-SSC-9701485", "name": "Active ALK binds JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9701485", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9701485" } ] }, { "id": "R-SSC-9701488", "name": "Active ALK phosphorylates JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9701488", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9701488" } ] }, { "id": "R-SSC-9701507", "name": "PTPN6 dephosphorylates JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9701507", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9701507" } ] }, { "id": "R-SSC-9701524", "name": "STAT3 is phosphorylated downstream of active ALK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9701524", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9701524" } ] }, { "id": "R-SSC-9842656", "name": "ALK binds ALKAL ligand", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9842656", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9842656" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RBJ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 581, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RBJ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBJ3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RBJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBJ3" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 87, "end_pos": 363, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RBM4-1", "uniprot_ac": "A0A5G2RBM4", "uniprot_id": "A0A5G2RBM4_PIG", "mass": { "chemical_mass": 35471.0, "monoisotopic_mass": 35471.0 }, "refseq": { "ac": "XP_003123512", "name": "olfactory receptor 10H4-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123512" }, "gene_names": [ { "name": "LOC100525684", "type": "recommended", "evidence": [ { "id": "A0A5G2RBM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4" } ] }, { "name": "LOC100525684", "type": "synonym", "evidence": [ { "id": "XP_003123512", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123512" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RBM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 10H4-like", "type": "synonym", "evidence": [ { "id": "XP_003123512", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123512" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100525684", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4", "locus": {} } ], "crossref": [ { "id": "A0A5G2RBM4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBM4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100525684", "url": "https://www.ncbi.nlm.nih.gov/gene/100525684", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525684", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525684", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HMLSTHH", "url": "https://omabrowser.org/oma/group/HMLSTHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RBM4", "url": "https://www.orthodb.org/?gene=A0A5G2RBM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003123512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123512", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RBM4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDQNHSTVSEFILIGFSNFPQQLLPTFFLLYLLMYLFTLLGNLLIMTTIWREHSLHTPMYLFLCALSTSEILFTVAITPRMLVDMLSTYRSISFTACASQMFFSFTFGFTHSFLLMIMGYDRYVAICHPLRYNVLMSTRDCARLVSWSWAGGSVMGMMVTMIVFHLTFCGSNEIHHFACHVLALLKLACGNETSSVTLGVILVCVTALMGCLFLIVLSYVFIVAAILRIPSAEGRHKTFSTCVSHLTIVIVHYGFASIIYLKPKGPRSMDSNTLMATTYTVFTPFLSPIIFSLRNKELKNAIKKNYLRKFFP", "length": 313, "header": "tr|A0A5G2RBM4-1|A0A5G2RBM4_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100525684 PE=3 SV=1 CANONICAL=A0A5G2RBM4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RBM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4/entry#A0A5G2RBM4-1", "sequence": { "sequence": "MTDQNHSTVSEFILIGFSNFPQQLLPTFFLLYLLMYLFTLLGNLLIMTTIWREHSLHTPMYLFLCALSTSEILFTVAITPRMLVDMLSTYRSISFTACASQMFFSFTFGFTHSFLLMIMGYDRYVAICHPLRYNVLMSTRDCARLVSWSWAGGSVMGMMVTMIVFHLTFCGSNEIHHFACHVLALLKLACGNETSSVTLGVILVCVTALMGCLFLIVLSYVFIVAAILRIPSAEGRHKTFSTCVSHLTIVIVHYGFASIIYLKPKGPRSMDSNTLMATTYTVFTPFLSPIIFSLRNKELKNAIKKNYLRKFFP", "length": 313, "header": "tr|A0A5G2RBM4-1|A0A5G2RBM4_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100525684 PE=3 SV=1 CANONICAL=A0A5G2RBM4-1" }, "locus": { "chromosome": "2", "start_pos": 61608289, "end_pos": 61607351, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076170.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076170.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073740.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073740.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525684", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525684", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBM4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RBM4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RBM4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBM4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RBM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBM4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 292, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 79 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RBP4-1", "uniprot_ac": "A0A5G2RBP4", "uniprot_id": "A0A5G2RBP4_PIG", "mass": { "chemical_mass": 82360.0, "monoisotopic_mass": 82360.0 }, "refseq": { "ac": "XP_003134130", "name": "hyaluronan mediated motility receptor isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134130" }, "gene_names": [ { "name": "HMMR", "type": "recommended", "evidence": [ { "id": "A0A5G2RBP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ] }, { "name": "HMMR", "type": "synonym", "evidence": [ { "id": "XP_003134130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134130" } ] } ], "protein_names": [ { "name": "Hyaluronan mediated motility receptor", "type": "synonym", "evidence": [ { "id": "A0A5G2RBP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4/entry#names_and_taxonomy" } ] }, { "name": "hyaluronan mediated motility receptor isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003134130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134130" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HMMR", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4", "locus": { "chromosome": "16", "start_pos": 60290001, "end_pos": 60331936, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017022", "url": "https://www.ensembl.org/id/ENSSSCG00000017022" } ] } } ], "crossref": [ { "id": "A0A5G2RBP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017022", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017022", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100515063", "url": "https://www.ncbi.nlm.nih.gov/gene/100515063", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001289", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001289", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515063", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515063", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NEAPTCA", "url": "https://omabrowser.org/oma/group/NEAPTCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RBP4", "url": "https://www.orthodb.org/?gene=A0A5G2RBP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18956", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18956", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18956:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18956:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15905", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15905", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2142845", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2142845", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2160916", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2160916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003134130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134130", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LED2", "url": "https://www.uniprot.org/uniprotkb/I3LED2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LED2-1", "url": "https://www.uniprot.org/uniprotkb/I3LED2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GSC4", "url": "https://www.uniprot.org/uniprotkb/K7GSC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GSC4-1", "url": "https://www.uniprot.org/uniprotkb/K7GSC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFPKAPLKRFNDPSGCAPSPGAYDVKTSEVLKGPVSFQKSQRFKQKKESQQNLNVDKDTTLPASARKVKTGGLKKESQKNDKDLKTLEKEIRVLVQQRGAQDKRIQDLEAELEKIEAKLNAAVREKTSLSASNASLEKQLIELTRTNELLKSKFSEDSNQKNMRILSLELMKLRNKRETKMRSMMAKQEGMEVKLQVTQKNLEESQGKIAQLEGKLVSIEKEKMDEKSETEKLLEYIEEISCASDQVEKYKLDIAHLEENLKEKNHEILSLKQSIEENVAMLSKQVDDLNAKCQQLEKEKGDLINRDRCRDENLNSEIQNLKERSNLERQEHEELQQKVLQIESLLQQEKELSSNLQQKLCSFQEEMIKERNLFEEELKQALDELDNLQQKEEQAETLVKQLEKEAESRAEELKLLEEKLKGKEAELEKSDAAHTQATLLLQERYNSTVQNLGDVTAQFESYKTLTASEIEDLKLENASLQEKVAKAEKSTEDVQHQILETENANQEYARMLLDLQTKSALKEAEIKEITVSSLKKITDLQNQLKQQGEDFKKQLEEETRKIEKENSMAELTEEMNKWRLLYEELYNKTKPFQLQLDAFEAEKQALLNEHGEAQEQLNKLRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRTQLAKRKQSEAKLQEELNKVLGIKHFDPSKAFLHESKENLVLKTPLKEGNTNCS", "length": 713, "header": "tr|A0A5G2RBP4-1|A0A5G2RBP4_PIG Isoform 1 of Hyaluronan mediated motility receptor OS=Sus scrofa OX=9823 GN=HMMR PE=4 SV=1 CANONICAL=A0A5G2RBP4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RBP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4/entry#A0A5G2RBP4-1", "sequence": { "sequence": "MSFPKAPLKRFNDPSGCAPSPGAYDVKTSEVLKGPVSFQKSQRFKQKKESQQNLNVDKDTTLPASARKVKTGGLKKESQKNDKDLKTLEKEIRVLVQQRGAQDKRIQDLEAELEKIEAKLNAAVREKTSLSASNASLEKQLIELTRTNELLKSKFSEDSNQKNMRILSLELMKLRNKRETKMRSMMAKQEGMEVKLQVTQKNLEESQGKIAQLEGKLVSIEKEKMDEKSETEKLLEYIEEISCASDQVEKYKLDIAHLEENLKEKNHEILSLKQSIEENVAMLSKQVDDLNAKCQQLEKEKGDLINRDRCRDENLNSEIQNLKERSNLERQEHEELQQKVLQIESLLQQEKELSSNLQQKLCSFQEEMIKERNLFEEELKQALDELDNLQQKEEQAETLVKQLEKEAESRAEELKLLEEKLKGKEAELEKSDAAHTQATLLLQERYNSTVQNLGDVTAQFESYKTLTASEIEDLKLENASLQEKVAKAEKSTEDVQHQILETENANQEYARMLLDLQTKSALKEAEIKEITVSSLKKITDLQNQLKQQGEDFKKQLEEETRKIEKENSMAELTEEMNKWRLLYEELYNKTKPFQLQLDAFEAEKQALLNEHGEAQEQLNKLRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRTQLAKRKQSEAKLQEELNKVLGIKHFDPSKAFLHESKENLVLKTPLKEGNTNCS", "length": 713, "header": "tr|A0A5G2RBP4-1|A0A5G2RBP4_PIG Isoform 1 of Hyaluronan mediated motility receptor OS=Sus scrofa OX=9823 GN=HMMR PE=4 SV=1 CANONICAL=A0A5G2RBP4-1" }, "locus": { "chromosome": "16", "start_pos": 60331844, "end_pos": 60291930, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088993.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088993.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073765.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073765.1" } ] } }, { "isoform_ac": "I3LED2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4/entry#I3LED2-1", "sequence": { "sequence": "MSFPKAPLKRFNDPSGCAPSPGAYDVKTSEVLKGPVSFQKSQRFKQKKESQQNLNVDKDTTLPASARKVKTGGLKKESQKNDKDLKTLEKEIRVLVQQRGAQDKRIQDLEAELEKIEAKLNAAVREKTSLSASNASLEKQLIELTRTNELLKSKFSEDSNQKNMRILSLELMKLRNKRETKMRSMMAKQEGMEVKLQVTQKNLEESQGKIAQLEGKLVSIEKEKMDEKSETEKLLEYIEEISCASDQVEKYKLDIAHLEENLKEKNHEILSLKQSIEENVAMLSKQVDDLNAKCQQLEKEKGDLINRDRCRDENLNSEIQNLKERSNLERQEHEELQQKVLQIESLLQQEKELSSNLQQKLCSFQEEMIKERNLFEEELKQALDELDNLQQKEEQAETLVKQLEKEAESRAEELKLLEEKLKGKEAELEKSDAAHTQATLLLQERYNSTVQNLGDVTAQFESYKTLTASEIEDLKLENASLQEKVAKAEKSTEDVQHQILETENANQEYARMLLDLQTKSALKEAEIKEITVSSLKKITDLQNQLKQQGEDFKKQLEEETRKIEKENSMAELTEEMNKWRLLYEELYNKTKPFQEVSKLRTQLAKRKQSEAKLQEELNKVLGIKHFDPSKAFLHESKENLVLKTPLKEGNTNCS", "length": 654, "header": "tr|I3LED2-1|A0A5G2RBP4_PIG Computationally mapped isoform of Hyaluronan mediated motility receptor OS=Sus scrofa OX=9823 GN=HMMR PE=4 SV=2 CANONICAL=A0A5G2RBP4-1" }, "locus": { "chromosome": "16", "start_pos": 60331844, "end_pos": 60291930, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030611.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030611.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022420.2", "url": "https://www.ensembl.org/id/ENSSSCP00000022420.2" } ] } }, { "isoform_ac": "K7GSC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4/entry#K7GSC4-1", "sequence": { "sequence": "MSFPKAPLKRFNDPSGCAPSPGAYDVKTSEVLKGPVSFQKSQRFKQKKESQKNDKDLKTLEKEIRVLVQQRGAQDKRIQDLEAELEKIEAKLNAAVREKTSLSASNASLEKQLIELTRTNELLKSKFSEDSNQKNMRILSLELMKLRNKRETKMRSMMAKQEGMEVKLQVTQKNLEESQGKIAQLEGKLVSIEKEKMDEKSETEKLLEYIEEISCASDQVEKYKLDIAHLEENLKEKNHEILSLKQSIEENVAMLSKQVDDLNAKCQQLEKEKGDLINRDRCRDENLNSEIQNLKERSNLERQEHEELQQKVLQIESLLQQEKELSSNLQQKLCSFQEEMIKERNLFEEELKQALDELDNLQQKEEQAETLVKQLEKEAESRAEELKLLEEKLKGKEAELEKSDAAHTQATLLLQERYNSTVQNLGDVTAQFESYKTLTASEIEDLKLENASLQEKVAKAEKSTEDVQHQILETENANQEYARMLLDLQTKSALKEAEIKEITVSSLKKITDLQNQLKQQGEDFKKQLEEETRKIEKENSMAELTEEMNKWRLLYEELYNKTKPFQLQLDAFEAEKQALLNEHGEAQEQLNKLRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRTQLAKRKQSEAKLQEELNKVLGIKHFDPSKAFLHESKENLVLKTPLKEGNTNCS", "length": 685, "header": "tr|K7GSC4-1|A0A5G2RBP4_PIG Computationally mapped isoform of Hyaluronan mediated motility receptor OS=Sus scrofa OX=9823 GN=HMMR PE=4 SV=3 CANONICAL=A0A5G2RBP4-1" }, "locus": { "chromosome": "16", "start_pos": 60331844, "end_pos": 60291930, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036191.4", "url": "https://www.ensembl.org/id/ENSSSCT00000036191.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030805.3", "url": "https://www.ensembl.org/id/ENSSSCP00000030805.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "K7GSC4", "url": "https://www.uniprot.org/uniprotkb/K7GSC4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515063", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515063", "resource": "KEGG Pathway" }, { "id": "R-SSC-2142845", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2142845", "resource": "Reactome", "description": "Hyaluronan metabolism" }, { "id": "R-SSC-2160916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2160916", "resource": "Reactome", "description": "Hyaluronan degradation" }, { "id": "R-SSC-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [ { "uniprot_canonical_ac": "O75330-1", "protein_name": "Hyaluronan mediated motility receptor", "gene_name": "HMMR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFPKAPLKRFNDPSGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKESQKNDKDLKILEKEIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYRAPMECQESWK", "length": 724 }, "evidence": [ { "id": "A0A5G2RBP4", "url": "https://omabrowser.org/oma/group/A0A5G2RBP4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97779-1", "protein_name": "Hyaluronan-mediated motility receptor", "gene_name": "Hmmr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGGVSYVGWLEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEEDLKEKDREILCLKQSLEEKVSFSKQIEDLTVKCQLLEAERDDLVSKDRERAESLSAEMQVLTEKLLLERQEYEKLQQNELQSQSLLQQEKELSAHLQQQLCSFQEEMTSERNVFKEQLKLALDELDAVQQKEEQSEKLVKQLEEETKSTAEQLRRLDDLLREKEIELEKRTAAHAQATVIAQEKYSDTAQTLRDVTAQLESYKSSTLKEIEDLKLENLTLQEKVAMAEKRVEDVQQQILTAESTNQEYAKVVQDLQNSSTLKEAEIKEITSSYLEKITDLQNQLRQQNEDFRKQLEEEGAKMTEKETAVTELTMEINKWRLLYEELYDKTKPFQQQLDAFEAEKQALLNEHGATQEQLSKIRDSYAQLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRSQLAKRKQNELRLQGELDKALGIRHFDPPKAFCHESKENVTLKTPLKEGNPNCC", "length": 498 }, "evidence": [ { "id": "A0A5G2RBP4", "url": "https://omabrowser.org/oma/group/A0A5G2RBP4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ], "pmid": "" }, { "name": "hyaluronan catabolic process", "id": "GO:0030214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030214", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "hyaluronic acid binding", "id": "GO:0005540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005540", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ], "pmid": "" }, { "name": "cargo receptor activity", "id": "GO:0038024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038024", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RBP4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 713, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RBP4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBP4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RBP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBP4" }, { "id": "PF15908", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Hyaluronan-mediated motility receptor C-terminal", "eco_id": "ECO_0000259", "start_pos": 554, "end_pos": 708, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 588, "end_pos": 590 }, { "start_pos": 711, "end_pos": 713 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RBS0-1", "uniprot_ac": "A0A5G2RBS0", "uniprot_id": "A0A5G2RBS0_PIG", "mass": { "chemical_mass": 105608.0, "monoisotopic_mass": 105608.0 }, "refseq": {}, "gene_names": [ { "name": "FBXO11", "type": "recommended", "evidence": [ { "id": "A0A5G2RBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ] } ], "protein_names": [ { "name": "F-box only protein 11", "type": "recommended", "evidence": [ { "id": "A0A5G2RBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FBXO11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0", "locus": { "chromosome": "3", "start_pos": 92792616, "end_pos": 92696441, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000029485", "url": "https://www.ensembl.org/id/ENSSSCG00000029485" } ] } } ], "crossref": [ { "id": "A0A5G2RBS0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000029485", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000029485", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19676", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19676", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22091", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22091", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006633", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006633", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22990", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22990", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22990:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22990:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05048", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05048", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LN00", "url": "https://www.uniprot.org/uniprotkb/I3LN00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LN00-1", "url": "https://www.uniprot.org/uniprotkb/I3LN00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSVRAANRRPRRVSRPRPVQQQQQPPQQPPPQPPQQPPQQQPPPPPQQQQQQPPPPPPPPPPLPQERNNAGERDDDVPADMVAEESGPGAQNSPYQLRRKTLLPKRTACPTKSNMEGASTSTTENFFGHRAKRARVSGKSQDLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRENMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIENTRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGVVKDSGVKSLKLCLEKRIFTGLLEENDIFRNAQAGVLISTNSHPVLRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRNAICVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSAPPIESNTLQHN", "length": 946, "header": "tr|A0A5G2RBS0-1|A0A5G2RBS0_PIG Isoform 1 of F-box only protein 11 OS=Sus scrofa OX=9823 GN=FBXO11 PE=4 SV=1 CANONICAL=A0A5G2RBS0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RBS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0/entry#A0A5G2RBS0-1", "sequence": { "sequence": "MNSVRAANRRPRRVSRPRPVQQQQQPPQQPPPQPPQQPPQQQPPPPPQQQQQQPPPPPPPPPPLPQERNNAGERDDDVPADMVAEESGPGAQNSPYQLRRKTLLPKRTACPTKSNMEGASTSTTENFFGHRAKRARVSGKSQDLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRENMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIENTRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGVVKDSGVKSLKLCLEKRIFTGLLEENDIFRNAQAGVLISTNSHPVLRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRNAICVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSAPPIESNTLQHN", "length": 946, "header": "tr|A0A5G2RBS0-1|A0A5G2RBS0_PIG Isoform 1 of F-box only protein 11 OS=Sus scrofa OX=9823 GN=FBXO11 PE=4 SV=1 CANONICAL=A0A5G2RBS0-1" }, "locus": { "chromosome": "3", "start_pos": 92791433, "end_pos": 92697222, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067829.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067829.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068064.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068064.1" } ] } }, { "isoform_ac": "I3LN00-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0/entry#I3LN00-1", "sequence": { "sequence": "MNSVRAANRRPRRVSRPRPVQQQQQPPQQPPPQPPQQPPQQQPPPPPQQQQQQPPPPPPPPPPLPQERNNAGERDMVAEESGPGAQNSPYQLRRKTLLPKRTACPTKSNMEGASTSTTENFFGHRAKRARVSGKSQDLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRENMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIENTRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPVLRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRNAICVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSAPPIESNTLQHN", "length": 919, "header": "tr|I3LN00-1|A0A5G2RBS0_PIG Computationally mapped isoform of F-box only protein 11 OS=Sus scrofa OX=9823 GN=FBXO11 PE=4 SV=3 CANONICAL=A0A5G2RBS0-1" }, "locus": { "chromosome": "3", "start_pos": 92791433, "end_pos": 92697222, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028062.3", "url": "https://www.ensembl.org/id/ENSSSCT00000028062.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025472.3", "url": "https://www.ensembl.org/id/ENSSSCP00000025472.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LN00", "url": "https://www.uniprot.org/uniprotkb/I3LN00" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" }, { "name": "protein-arginine N-methyltransferase activity", "id": "GO:0016274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016274", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" }, { "name": "negative regulation of epithelial to mesenchymal transition", "id": "GO:0010719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010719", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 830, "end_pos": 832, "annotation": "n_glycosylation_sequon" }, { "start_pos": 876, "end_pos": 878, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RBS0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 946, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RBS0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RBS0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 151, "end_pos": 197, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS0" }, { "id": "PS51157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBR-type", "eco_id": "ECO_0000259", "start_pos": 852, "end_pos": 923, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 367, "end_pos": 369 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 830, "end_pos": 832 }, { "start_pos": 876, "end_pos": 878 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RG90-1", "uniprot_ac": "A0A5G2RG90", "uniprot_id": "A0A5G2RG90_PIG", "mass": { "chemical_mass": 56027.0, "monoisotopic_mass": 56027.0 }, "refseq": { "ac": "XP_013845697", "name": "chromaffin granule amine transporter isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845697" }, "gene_names": [ { "name": "SLC18A1", "type": "recommended", "evidence": [ { "id": "A0A5G2RG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90" } ] }, { "name": "SLC18A1", "type": "synonym", "evidence": [ { "id": "XP_013845697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845697" } ] } ], "protein_names": [ { "name": "Solute carrier family 18 member A1", "type": "synonym", "evidence": [ { "id": "A0A5G2RG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90/entry#names_and_taxonomy" } ] }, { "name": "chromaffin granule amine transporter isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013845697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845697" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC18A1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90", "locus": { "chromosome": "14", "start_pos": 4243557, "end_pos": 4275243, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009601", "url": "https://www.ensembl.org/id/ENSSSCG00000009601" } ] } } ], "crossref": [ { "id": "A0A5G2RG90", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RG90", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009601", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009601", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100154435", "url": "https://www.ncbi.nlm.nih.gov/gene/100154435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154435", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154435", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FGWCVDR", "url": "https://omabrowser.org/oma/group/FGWCVDR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RG90", "url": "https://www.orthodb.org/?gene=A0A5G2RG90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23506", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23506", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23506:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23506:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013845697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845697", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "73739", "url": "https://www.rhea-db.org/rhea/73739", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73743", "url": "https://www.rhea-db.org/rhea/73743", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RBS9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG90-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RMZ9", "url": "https://www.uniprot.org/uniprotkb/F1RMZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RMZ9-1", "url": "https://www.uniprot.org/uniprotkb/F1RMZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRAVWDAPQQLLKKGRGSPKLVLLVVFVALLLDNMLLTVVVPIVPTYLYAIEFKDVNTSLYLGPTSTTQPALASAFSTIFSFFENNTVAIEESVPSGTAWTNGTSGTTPPPVTEAIATHKNNCFQGTEFLKEENIWVGVLFASKALMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFMSTVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGKAMGIALGGLALGVLVGAPFGSVMYVFFGKVVPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLLTLLQDPYILVAAGSLCFANMGVAMLEPTLPIWMLQTMCPPEWHLGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLVGMVIVGTSLLCVPLAHNIFGLIGPNAGLGFSIGMVDSSMMPIMGHLVDLRHAPVYGSVYAIADVAFCMGFAIGPSTGGAIVRAIGFPWLMVIIGVVNIIYAPLCCYLRSPPAKEEKLAILSQDCPLETRMYAAEPHLREFPLGDDSDAEPASEE", "length": 524, "header": "tr|A0A5G2RG90-1|A0A5G2RG90_PIG Isoform 1 of Solute carrier family 18 member A1 OS=Sus scrofa OX=9823 GN=SLC18A1 PE=3 SV=1 CANONICAL=A0A5G2RG90-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RBS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90/entry#A0A5G2RBS9-1", "sequence": { "sequence": "MLRAVWDAPQQLLKKGRGSPKLVLLVVFVALLLDNMLLTVVVPIVPTYLYAIEFKDVNTSLYLGPTSTTQPALASAFSTIFSFFENNTVAIEESVPSGTAWTNGTSGTTPPPVTEAIATHKNNCFQGTEFLKEENIWVGVLFASKALMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFMSTVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGKAMGIALGGLALGVLVGAPFGSVMYVFFGKVVPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLLTLLQDPYILVAAGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLVGMVIVGTSLLCVPLAHNIFGLIGPNAGLGFSIGMVDSSMMPIMGHLVDLRHAPVYGSVYAIADVAFCMGFAIGPSTGGAIVRAIGFPWLMVIIGVVNIIYAPLCCYLRSPPAKEEKLAILSQDCPLETRMYAAEPHLREFPLGDDSDAEPASEE", "length": 492, "header": "tr|A0A5G2RBS9-1|A0A5G2RG90_PIG Computationally mapped isoform of Solute carrier family 18 member A1 OS=Sus scrofa OX=9823 GN=SLC18A1 PE=3 SV=1 CANONICAL=A0A5G2RG90-1" }, "locus": { "chromosome": "14", "start_pos": 4271893, "end_pos": 4244714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089527.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089527.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071632.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071632.1" } ] } }, { "isoform_ac": "A0A5G2RG90-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90/entry#A0A5G2RG90-1", "sequence": { "sequence": "MLRAVWDAPQQLLKKGRGSPKLVLLVVFVALLLDNMLLTVVVPIVPTYLYAIEFKDVNTSLYLGPTSTTQPALASAFSTIFSFFENNTVAIEESVPSGTAWTNGTSGTTPPPVTEAIATHKNNCFQGTEFLKEENIWVGVLFASKALMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFMSTVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGKAMGIALGGLALGVLVGAPFGSVMYVFFGKVVPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLLTLLQDPYILVAAGSLCFANMGVAMLEPTLPIWMLQTMCPPEWHLGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLVGMVIVGTSLLCVPLAHNIFGLIGPNAGLGFSIGMVDSSMMPIMGHLVDLRHAPVYGSVYAIADVAFCMGFAIGPSTGGAIVRAIGFPWLMVIIGVVNIIYAPLCCYLRSPPAKEEKLAILSQDCPLETRMYAAEPHLREFPLGDDSDAEPASEE", "length": 524, "header": "tr|A0A5G2RG90-1|A0A5G2RG90_PIG Isoform 1 of Solute carrier family 18 member A1 OS=Sus scrofa OX=9823 GN=SLC18A1 PE=3 SV=1 CANONICAL=A0A5G2RG90-1" }, "locus": { "chromosome": "14", "start_pos": 4271893, "end_pos": 4244714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072338.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072338.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070184.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070184.1" } ] } }, { "isoform_ac": "F1RMZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90/entry#F1RMZ9-1", "sequence": { "sequence": "MLRAVWDAPQQLLKKGRGSPKLVLLVVFVALLLDNMLLTVVVPIVPTYLYAIEFKDVNTSLYLGPTSTTQPALASAFSTIFSFFENNTVAIEESVPSGTAWTNGTSGTTPPPVTEAIATHKNNCFQGTEFLKEENIWVGVLFASKALMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFMSTVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGKAMGIALGGLALGVLVGAPFGSVMYVFFGKVVPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLLTLLQDPYILVAAGSLCFANMGVAMLEPTLPIWMLQTMCPPEWHLGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLVGMVIVGTSLLCVPLAHNIFGLIGPNAGLGFSIGMVDSSMMPIMGHLVDLRHAPVYGSVYAIADVAFCMGFAIGNSEPGLPPGDPDVCSRAAPEGVSFGGRQRCGAGQ", "length": 477, "header": "tr|F1RMZ9-1|A0A5G2RG90_PIG Computationally mapped isoform of Solute carrier family 18 member A1 OS=Sus scrofa OX=9823 GN=SLC18A1 PE=3 SV=5 CANONICAL=A0A5G2RG90-1" }, "locus": { "chromosome": "14", "start_pos": 4271893, "end_pos": 4244721, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010524.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010524.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010249.5", "url": "https://www.ensembl.org/id/ENSSSCP00000010249.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RMZ9", "url": "https://www.uniprot.org/uniprotkb/F1RMZ9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154435", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154435", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MMN4-1", "protein_name": "Chromaffin granule amine transporter isoform X1", "gene_name": "Slc18a1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFQVVLGAPQRLLKEGRESRQLVLVVVFVALLLDNMLLTVVVPIVPTFLYATEFRDVNSSLHRGPSVRSQQAVTSPDFSTIFSFFDNTTTTAEAHVLFHVAWTNGTIPPPVTEAGSAPKNSCLQGIEFLEEENIRVGVLFASKALMQLLVNPFVGPLTNRIGYHIPMFAGFMIMFLSTLMFAFSGTYALLFVARTLQGIGSSFSSVAGLGMLASVYTDNHERGRAMGIALGGLALGLLVGAPFGSVMYEFVGKSSPFLILAFLALLDGALQLCILWPSKVSSENAMGTPLLTLLKDPYILVAAGSICLANMGVAILEPTLPIWMMQTMCSPEWQLGLAFLPASVAYLIGTNLFGVLANKMGRWLCALVGMVAVGISLLCVPLAHNIFGLIGPNAGLGFAIGMVDSSLMPIMGYLVDLRHTSVYGSVYAIADVAFCIGFAIGPSTGGAVVQVIGFPWLMVVIGVINIIYAPLCCFLQNPPAKEEKLAILSQECPMETQMYASRKPTKEFPLGDNSDDPGSEE", "length": 521 }, "evidence": [ { "id": "A0A5G2RG90", "url": "https://omabrowser.org/oma/group/A0A5G2RG90/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9SKR9-1", "protein_name": "Solute carrier family 18 member A1", "gene_name": "SLC18A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLRTVLDAPQRLLKKGRESRKLVLLVVFVALLLDNMLLTVVVPIVPTYLYAIEFKDINGSLYLGSATTTQPSLTPAFSTILSFFENNTVAVEESVPSGIARTSSISGTIPPVTEAIPAHGNNCFQATEFLKEENLWVGVLFASKALMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFISTVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLACVYTDDHERGRAMGIALGGLALGVLVGAPFGSVTYVFLGKTVPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLLTLLRDPYILVAAGSICLANMGVAMLEPTLPIWMLQTMCAPEWQLGLAFLPASVSYLIGTSLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHDIFGLIGPNAGLGISIGMVDSSMMPIMGHLVDLRHAPVYGSVYAIADVAFCLGFAVGPSTGGAIVRAIGFPWLMVITGVTDIIYAPLCYYLRSPPAKEEKLAVLSQDCPMETRMYAAEKHTRQFPLGEDSDEEPGCEE", "length": 523 }, "evidence": [ { "id": "A0A5G2RG90", "url": "https://omabrowser.org/oma/group/A0A5G2RG90/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P54219-1", "protein_name": "Chromaffin granule amine transporter", "gene_name": "SLC18A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRSPPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE", "length": 525 }, "evidence": [ { "id": "A0A5G2RG90", "url": "https://omabrowser.org/oma/group/A0A5G2RG90/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q01818-1", "protein_name": "Chromaffin granule amine transporter", "gene_name": "Slc18a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLQVVLGAPQRLLKEGRQSRKLVLVVVFVALLLDNMLLTVVVPIVPTFLYATEFKDSNSSLHRGPSVSSQQALTSPAFSTIFSFFDNTTTTVEEHVPFRVTWTNGTIPPPVTEASSVPKNNCLQGIEFLEEENVRIGILFASKALMQLLVNPFVGPLTNRIGYHIPMFVGFMIMFLSTLMFAFSGTYALLFVARTLQGIGSSFSSVAGLGMLASVYTDNYERGRAMGIALGGLALGLLVGAPFGSVMYEFVGKSSPFLILAFLALLDGALQLCILWPSKVSPESAMGTSLLTLLKDPYILVAAGSICLANMGVAILEPTLPIWMMQTMCSPEWQLGLAFLPASVAYLIGTNLFGVLANKMGRWLCSLVGMVAVGISLLCVPLAHNIFGLIGPNAGLGFAIGMVDSSLMPIMGYLVDLRHTSVYGSVYAIADVAFCVGFAIGPSTGGVIVQVIGFPWLMVIIGTINIIYAPLCCFLQNPPAKEEKRAILSQECPTETQMYTFQKPTKAFPLGENSDDPSSGE", "length": 521 }, "evidence": [ { "id": "A0A5G2RG90", "url": "https://omabrowser.org/oma/group/A0A5G2RG90/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R090-1", "protein_name": "Chromaffin granule amine transporter", "gene_name": "Slc18a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQVVLGAPQRLLKEGRQSRKLVLVVVFVALLLDNMLLTVVVPIVPTFLYATEFKDINSSLLRGPSVSSQQALTSPAFSTTFSFFDNTTMTVEEHVPFRVAWINGTIPPPVTEAGSVPKNNCLQGIEFLEEENVRIGILFASKALMQLLVNPFVGPLTNRIGYHIPMFVGFMIMFLSTLMFAFSGTYALLFVARTLQGIGSSFSSVAGLGMLASVYTDNYERGRAMGIALGGLALGLLVGAPFGSVMYEFVGKSSPFLILAFLALLDGALQFCILWPSKVSPESAMGTPLLTLLKDPYILVAAGSICLANMGVAILEPTLPIWMMQTMCSPEWQLGLAFLPASVAYLIGTNLFGVLANKMGRWLCSLVGMVAVGISLLCVPLAHNIFGLIGPNAGLGFAIGMVDSSLMPIMGYLVDLRHTSVYGSVYAIADVAFCVGFAIGPSTGGVIVPVIGFPWLMVIIGTINIIYAPLCCFLQNPPAKEEELAILNQECPTETQMYTIQRPTKEFPLGENSDDPGSEE", "length": 521 }, "evidence": [ { "id": "A0A5G2RG90", "url": "https://omabrowser.org/oma/group/A0A5G2RG90/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90" } ], "pmid": "" }, { "name": "serotonin:sodium:chloride symporter activity", "id": "GO:0005335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005335", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90" } ], "pmid": "" }, { "name": "monoamine:proton antiporter activity", "id": "GO:0015311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015311", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "establishment of localization in cell", "id": "GO:0051649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051649", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90" } ], "pmid": "" }, { "name": "serotonin transport", "id": "GO:0006837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006837", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90" } ], "pmid": "" }, { "name": "neurotransmitter transport", "id": "GO:0006836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006836", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90" } ], "pmid": "" }, { "name": "aminergic neurotransmitter loading into synaptic vesicle", "id": "GO:0015842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015842", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "73739", "name": "", "equation": "dopamine(in) + 2 H(+)(out) = dopamine(out) + 2 H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73739", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73739" } ] }, { "id": "73743", "name": "", "equation": "serotonin(in) + 2 H(+)(out) = serotonin(out) + 2 H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73743", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73743" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RG90-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 524, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RG90-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RG90" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG90" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 483, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RC16-1", "uniprot_ac": "A0A5G2RC16", "uniprot_id": "A0A5G2RC16_PIG", "mass": { "chemical_mass": 38313.0, "monoisotopic_mass": 38313.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "L1 transposable element RRM domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC16/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC16", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC16" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC16", "locus": {} } ], "crossref": [ { "id": "A0A5G2RC16", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC16", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045226", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045226", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RC16", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RC16-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPALRKYSTAVTRQTLPDNGEYNSLRRKKTSKMKKLRNHPQSNQQENSPKTVNNETDLCSLTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAKMQTELRAVKTRMNNAEERISDMEDRIMEITQSSQQTENRIKKLESNIRDLWDNIKRANLCIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGVKIQEAQRAPNKLNPNRPTPRHIIIKMPKVSDKERILKAAREKQNVTYKGTPIRISADFATETLQARREWQEIFKVLEGKNTQPRILYPARISFKIEGEIKNFSNKQKLKEYSNTKPRLKEILKGLL", "length": 328, "header": "tr|A0A5G2RC16-1|A0A5G2RC16_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RC16-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RC16-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC16/entry#A0A5G2RC16-1", "sequence": { "sequence": "MPALRKYSTAVTRQTLPDNGEYNSLRRKKTSKMKKLRNHPQSNQQENSPKTVNNETDLCSLTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAKMQTELRAVKTRMNNAEERISDMEDRIMEITQSSQQTENRIKKLESNIRDLWDNIKRANLCIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGVKIQEAQRAPNKLNPNRPTPRHIIIKMPKVSDKERILKAAREKQNVTYKGTPIRISADFATETLQARREWQEIFKVLEGKNTQPRILYPARISFKIEGEIKNFSNKQKLKEYSNTKPRLKEILKGLL", "length": 328, "header": "tr|A0A5G2RC16-1|A0A5G2RC16_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RC16-1" }, "locus": { "chromosome": "14", "start_pos": 82167168, "end_pos": 82166185, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091149.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091149.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071742.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071742.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC16", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC16" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC16", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC16" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC16", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC16" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC16", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RC16-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 328, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RC16-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC16" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC16" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 164, "end_pos": 259, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC16" }, { "id": "PF17490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element dsRBD-like", "eco_id": "ECO_0000259", "start_pos": 263, "end_pos": 325, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 246, "end_pos": 248 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RC17-1", "uniprot_ac": "A0A5G2RC17", "uniprot_id": "A0A5G2RC17_PIG", "mass": { "chemical_mass": 34349.0, "monoisotopic_mass": 34349.0 }, "refseq": { "ac": "XP_013849774", "name": "olfactory receptor 1013-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849774" }, "gene_names": [ { "name": "LOC100519587", "type": "recommended", "evidence": [ { "id": "A0A5G2RC17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17" } ] }, { "name": "LOC100519587", "type": "synonym", "evidence": [ { "id": "XP_013849774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849774" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RC17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1013-like", "type": "synonym", "evidence": [ { "id": "XP_013849774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849774" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100519587", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17", "locus": {} } ], "crossref": [ { "id": "A0A5G2RC17", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC17", "database": "AlphaFoldDB", "categories": [] }, { "id": "100519587", "url": "https://www.ncbi.nlm.nih.gov/gene/100519587", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519587", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519587", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RC17", "url": "https://www.orthodb.org/?gene=A0A5G2RC17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013849774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849774", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RC17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RC17-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERSNYTVTDFIMVGFTTDPVVQLVLFVTFLGINSATVLGNTTLMVLICKDSRLHTPMYFFIGNLSFLDLWYSSVYTPKILVTCISEDKSISFAGCVAQFFFSAGLTYSECYPPAAMAYDHYMAISKLLLYSQAMPIKLCAFFIAPSYLGGFINAFIVTKGTFALNFCSNNIIDDFFCDIPPLVKLACGRKDSYQTVLYFVLASNVITPIVLIIASYLFIITTILKIRSTQGRLKAFSTCSSHLISVTLYYGSILYIYSRPQSSYSLDRDKIVSTFYTVVFPMLNPMIYSLRNKDMKEALNKLLK", "length": 305, "header": "tr|A0A5G2RC17-1|A0A5G2RC17_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100519587 PE=3 SV=1 CANONICAL=A0A5G2RC17-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RC17-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17/entry#A0A5G2RC17-1", "sequence": { "sequence": "MERSNYTVTDFIMVGFTTDPVVQLVLFVTFLGINSATVLGNTTLMVLICKDSRLHTPMYFFIGNLSFLDLWYSSVYTPKILVTCISEDKSISFAGCVAQFFFSAGLTYSECYPPAAMAYDHYMAISKLLLYSQAMPIKLCAFFIAPSYLGGFINAFIVTKGTFALNFCSNNIIDDFFCDIPPLVKLACGRKDSYQTVLYFVLASNVITPIVLIIASYLFIITTILKIRSTQGRLKAFSTCSSHLISVTLYYGSILYIYSRPQSSYSLDRDKIVSTFYTVVFPMLNPMIYSLRNKDMKEALNKLLK", "length": 305, "header": "tr|A0A5G2RC17-1|A0A5G2RC17_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100519587 PE=3 SV=1 CANONICAL=A0A5G2RC17-1" }, "locus": { "chromosome": "AEMK02000449.1", "start_pos": 933136, "end_pos": 932222, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074704.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074704.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068159.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068159.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519587", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519587", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RC17-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 305, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RC17-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC17" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RC17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC17" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RC32-1", "uniprot_ac": "A0A5G2RC32", "uniprot_id": "A0A5G2RC32_PIG", "mass": { "chemical_mass": 38170.0, "monoisotopic_mass": 38170.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RC32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC32/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC32", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC32#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC32", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC32" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC32", "locus": {} } ], "crossref": [ { "id": "A0A5G2RC32", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC32", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RC32", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RC32-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFCVISDELSVCCLCWTHPNLMENQNNVTEFVFMRLWGNKQTELLFLFLFLLCYLTVLMGNCVVLLTITCSHLLQQPMYYFLSHLSLMDLFYTSSVVPRLMRDLAAARKNISYNNCMTQLFTAHLMAGVEILILVSMAFDRYVAIVKPLHYLVIMNRQRCTMLVIMAWVVGFGHSIALLLVMLSLPFCGPNQIDHYLCDVKPLLKLVCSDIHLVNILMIANSGVVVIVVFLVLVISYIIILYSLRTHSSVGRRKALSTCSSHIMVVVLFFVPCIYIYVLPAGNENKDKEISVSYTVIAPMLNPLIYTLRNEEMKIAMRKVWFKIAHLELTQMR", "length": 333, "header": "tr|A0A5G2RC32-1|A0A5G2RC32_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RC32-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RC32-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC32/entry#A0A5G2RC32-1", "sequence": { "sequence": "MFCVISDELSVCCLCWTHPNLMENQNNVTEFVFMRLWGNKQTELLFLFLFLLCYLTVLMGNCVVLLTITCSHLLQQPMYYFLSHLSLMDLFYTSSVVPRLMRDLAAARKNISYNNCMTQLFTAHLMAGVEILILVSMAFDRYVAIVKPLHYLVIMNRQRCTMLVIMAWVVGFGHSIALLLVMLSLPFCGPNQIDHYLCDVKPLLKLVCSDIHLVNILMIANSGVVVIVVFLVLVISYIIILYSLRTHSSVGRRKALSTCSSHIMVVVLFFVPCIYIYVLPAGNENKDKEISVSYTVIAPMLNPLIYTLRNEEMKIAMRKVWFKIAHLELTQMR", "length": 333, "header": "tr|A0A5G2RC32-1|A0A5G2RC32_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RC32-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 247307, "end_pos": 246309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099515.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099515.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077379.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077379.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC32", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC32" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC32", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC32" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC32", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC32" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC32", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RC32-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 333, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RC32-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC32" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RC32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC32" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 306, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 27, "end_pos": 29 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RC38-1", "uniprot_ac": "A0A5G2RC38", "uniprot_id": "A0A5G2RC38_PIG", "mass": { "chemical_mass": 22467.0, "monoisotopic_mass": 22467.0 }, "refseq": {}, "gene_names": [ { "name": "ISCA2", "type": "recommended", "evidence": [ { "id": "A0A5G2RC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" } ] } ], "protein_names": [ { "name": "Iron-sulfur cluster assembly 2 homolog, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A5G2RC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38/entry#names_and_taxonomy" } ] }, { "name": "HESB-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A5G2RC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38#function" }, { "database": "UniProtKB", "id": "ARBA00057540", "url": "https://www.uniprot.org/uniprotkb/ARBA00057540#function" }, { "database": "UniProtKB", "id": "F1S3F3", "url": "https://www.uniprot.org/uniprotkb/F1S3F3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ISCA2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38", "locus": { "chromosome": "7", "start_pos": 97743911, "end_pos": 97740491, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002367", "url": "https://www.ensembl.org/id/ENSSSCG00000002367" } ] } } ], "crossref": [ { "id": "A0A5G2RC38", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC38", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002367", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002367", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PWALREM", "url": "https://omabrowser.org/oma/group/PWALREM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR43011", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43011", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43011:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43011:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01521", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01521", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1362409", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1362409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9854311", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9854311", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RC38-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3F3", "url": "https://www.uniprot.org/uniprotkb/F1S3F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3F3-1", "url": "https://www.uniprot.org/uniprotkb/F1S3F3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVRGLYITAAALRAVTPWQRGSRLLAASRGPWALREMSSSNPEAGEGQIHLTDSCVQVRGRTRGARGWRGLGVGVLSLGLSVSLPCLEFLTSLPAFQRLLEITEGSEFLRLEVEGGGCSGFQYKFSLDTVINPDDRVFEQGGARVVVDSDSLAFVKGAQVDFSQELIRSSFQVLNNPQAQQGCSYFHGRRQKAAYGGSVCVTLLSH", "length": 208, "header": "tr|A0A5G2RC38-1|A0A5G2RC38_PIG Isoform 1 of Iron-sulfur cluster assembly 2 homolog, mitochondrial OS=Sus scrofa OX=9823 GN=ISCA2 PE=1 SV=1 CANONICAL=A0A5G2RC38-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RC38-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38/entry#A0A5G2RC38-1", "sequence": { "sequence": "MAAVRGLYITAAALRAVTPWQRGSRLLAASRGPWALREMSSSNPEAGEGQIHLTDSCVQVRGRTRGARGWRGLGVGVLSLGLSVSLPCLEFLTSLPAFQRLLEITEGSEFLRLEVEGGGCSGFQYKFSLDTVINPDDRVFEQGGARVVVDSDSLAFVKGAQVDFSQELIRSSFQVLNNPQAQQGCSYFHGRRQKAAYGGSVCVTLLSH", "length": 208, "header": "tr|A0A5G2RC38-1|A0A5G2RC38_PIG Isoform 1 of Iron-sulfur cluster assembly 2 homolog, mitochondrial OS=Sus scrofa OX=9823 GN=ISCA2 PE=1 SV=1 CANONICAL=A0A5G2RC38-1" }, "locus": { "chromosome": "7", "start_pos": 97743883, "end_pos": 97740507, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068881.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068881.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071767.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071767.1" } ] } }, { "isoform_ac": "F1S3F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38/entry#F1S3F3-1", "sequence": { "sequence": "MAAVRGLYITAAALRAVTPWQRGSRLLAASRGPWALREMSSSNPEAGEGQIHLTDSCVQRLLEITEGSEFLRLEVEGGGCSGFQYKFSLDTVINPDDRVFEQGGARVVVDSDSLAFVKGAQVDFSQELIRSSFQVLNNPQAQQGCSYFHGRRQKAAYGGSVCVTLLSH", "length": 168, "header": "tr|F1S3F3-1|A0A5G2RC38_PIG Computationally mapped isoform of Iron-sulfur cluster assembly 2 homolog, mitochondrial OS=Sus scrofa OX=9823 GN=ISCA2 PE=1 SV=2 CANONICAL=A0A5G2RC38-1" }, "locus": { "chromosome": "7", "start_pos": 97743883, "end_pos": 97740507, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002631.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002631.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002565.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002565.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 18, "start_aa": "Thr", "end_pos": 18, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr18", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3F3", "url": "https://www.uniprot.org/uniprotkb/F1S3F3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1362409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1362409", "resource": "Reactome", "description": "Mitochondrial iron-sulfur cluster biogenesis" }, { "id": "R-SSC-9854311", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9854311", "resource": "Reactome", "description": "Maturation of TCA enzymes and regulation of TCA cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" } ], "pmid": "" }, { "name": "mitochondrial [4Fe-4S] assembly complex", "id": "GO:0120510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120510", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC38", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RC38-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 208, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RC38-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC38" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC38" }, { "id": "PF01521", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01521" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Core", "eco_id": "ECO_0000259", "start_pos": 97, "end_pos": 185, "start_aa": "Ala", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 18 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RC51-1", "uniprot_ac": "A0A5G2RC51", "uniprot_id": "A0A5G2RC51_PIG", "mass": { "chemical_mass": 18772.0, "monoisotopic_mass": 18772.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF580", "type": "recommended", "evidence": [ { "id": "A0A5G2RC51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ] } ], "protein_names": [ { "name": "Zinc finger protein 580", "type": "recommended", "evidence": [ { "id": "A0A5G2RC51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in the regulation of endothelial cell proliferation and migration. Mediates H(2)O(2)-induced leukocyte chemotaxis by elevating interleukin-8 production and may play a role in inflammation. May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51#function" }, { "database": "UniProtKB", "id": "ARBA00057609", "url": "https://www.uniprot.org/uniprotkb/ARBA00057609#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF580", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51", "locus": { "chromosome": "6", "start_pos": 59764373, "end_pos": 59761947, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031349", "url": "https://www.ensembl.org/id/ENSSSCG00000031349" } ] } } ], "crossref": [ { "id": "A0A5G2RC51", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC51", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000031349", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031349", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VWPRVGF", "url": "https://omabrowser.org/oma/group/VWPRVGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RC51-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLPPRPPHPRSSSPEAMDPPPPKAPPFPKTEGPSSSPSSAAGPRPPRLGRHLLIDANGVPYTYTVQLEEEPRGPPQREAPPGEPGPRKGYSCPECARVFASPLRLQSHRVSHSDLKPFTCGACGKAFKRSSHLSRHRATHRARAGPPHTCPLCPRRFQDAAELAQHVRLH", "length": 172, "header": "tr|A0A5G2RC51-1|A0A5G2RC51_PIG Isoform 1 of Zinc finger protein 580 OS=Sus scrofa OX=9823 GN=ZNF580 PE=4 SV=2 CANONICAL=A0A5G2RC51-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RC51-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51/entry#A0A5G2RC51-1", "sequence": { "sequence": "MLLLPPRPPHPRSSSPEAMDPPPPKAPPFPKTEGPSSSPSSAAGPRPPRLGRHLLIDANGVPYTYTVQLEEEPRGPPQREAPPGEPGPRKGYSCPECARVFASPLRLQSHRVSHSDLKPFTCGACGKAFKRSSHLSRHRATHRARAGPPHTCPLCPRRFQDAAELAQHVRLH", "length": 172, "header": "tr|A0A5G2RC51-1|A0A5G2RC51_PIG Isoform 1 of Zinc finger protein 580 OS=Sus scrofa OX=9823 GN=ZNF580 PE=4 SV=2 CANONICAL=A0A5G2RC51-1" }, "locus": { "chromosome": "6", "start_pos": 59763938, "end_pos": 59763423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078130.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078130.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068194.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068194.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A911-1", "protein_name": "Zinc finger protein 580", "gene_name": "Zfp580", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLPPRPPHPRSSSPEVMDPPPPKTPPFPKAEGPSSTSSSVAGPRPPRLGRHLLIDANGVPYTYTVQLEEEPRGPPQREATPGEPGPRKGYSCPECARVFASPLRLQSHRVSHSDLKPFTCGACGKAFKRSSHLSRHRATHRARAGPPHTCPLCPRRFQDAAELAQHVRLH", "length": 172 }, "evidence": [ { "id": "A0A5G2RC51", "url": "https://omabrowser.org/oma/group/A0A5G2RC51/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3MX43-1", "protein_name": "Zinc finger protein 580", "gene_name": "ZNF580", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLLPPRPPHPRASSPEAMDPPPPKAPPFPPAEGPASTASSAAGPRPPRLGRHLLIDANGVPYTYTAPLEEEPRGPTPREAPPGEPGPRKGYSCPECARVFASPLRLQSHRVSHSDLKPFTCGACGKAFKRSSHLSRHRATHRARAGPPHACPLCPRRFQDAAELAQHVRLH", "length": 172 }, "evidence": [ { "id": "A0A5G2RC51", "url": "https://omabrowser.org/oma/group/A0A5G2RC51/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9DB38-1", "protein_name": "Zinc finger protein 580", "gene_name": "Znf580", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLPPRPPHPRSSSPEVMDPPPPKTPPFPKAEGPSSTSSSVAGPRPPRLGRHLLIDANGVPYTYTVQLEEEPRGPPQREATPGEPGPRKGYSCPECARVFASPLRLQSHRVSHSDLKPFTCGACGKAFKRSSHLSRHRATHRARAGPPHTCPLCPRRFQDAAELAQHVRLH", "length": 172 }, "evidence": [ { "id": "A0A5G2RC51", "url": "https://omabrowser.org/oma/group/A0A5G2RC51/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UK33-1", "protein_name": "Zinc finger protein 580", "gene_name": "ZNF580", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLLPPRPPHPRSSSPEAMDPPPPKAPPFPKAEGPSSTPSSAAGPRPPRLGRHLLIDANGVPYTYTVQLEEEPRGPPQREAPPGEPGPRKGYSCPECARVFASPLRLQSHRVSHSDLKPFTCGACGKAFKRSSHLSRHRATHRARAGPPHTCPLCPRRFQDAAELAQHVRLH", "length": 172 }, "evidence": [ { "id": "A0A5G2RC51", "url": "https://omabrowser.org/oma/group/A0A5G2RC51/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "pmid": "" }, { "name": "chemotaxis", "id": "GO:0006935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006935", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell migration", "id": "GO:0010595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010595", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell proliferation", "id": "GO:0001938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001938", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "pmid": "" }, { "name": "cellular response to hydrogen peroxide", "id": "GO:0070301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "pmid": "" }, { "name": "positive regulation of interleukin-8 production", "id": "GO:0032757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032757", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "pmid": "" }, { "name": "positive regulation of leukocyte chemotaxis", "id": "GO:0002690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002690", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RC51-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 172, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RC51-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC51" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RC51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC51" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 119, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RC85-1", "uniprot_ac": "A0A5G2RC85", "uniprot_id": "A0A5G2RC85_PIG", "mass": { "chemical_mass": 87862.0, "monoisotopic_mass": 87862.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100515049", "type": "recommended", "evidence": [ { "id": "A0A5G2RC85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ] } ], "protein_names": [ { "name": "Angiotensin-converting enzyme", "type": "recommended", "evidence": [ { "id": "A0A5G2RC85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85/entry#names_and_taxonomy" } ] }, { "name": "3.4.-.-", "type": "synonym", "evidence": [ { "id": "A0A5G2RC85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Soluble form that is released in blood plasma and other body fluids following proteolytic cleavage in the juxtamembrane stalk region.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85#function" }, { "database": "UniProtKB", "id": "ARBA00037200", "url": "https://www.uniprot.org/uniprotkb/ARBA00037200#function" }, { "database": "UniProtKB", "id": "I3LC15", "url": "https://www.uniprot.org/uniprotkb/I3LC15#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100515049", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85", "locus": {} } ], "crossref": [ { "id": "A0A5G2RC85", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC85", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000023612", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000023612", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06461", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06461", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FYRQIHG", "url": "https://omabrowser.org/oma/group/FYRQIHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10514", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10514", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10514:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10514:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01401", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01401", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "63560", "url": "https://www.rhea-db.org/rhea/63560", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70675", "url": "https://www.rhea-db.org/rhea/70675", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71451", "url": "https://www.rhea-db.org/rhea/71451", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71455", "url": "https://www.rhea-db.org/rhea/71455", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71459", "url": "https://www.rhea-db.org/rhea/71459", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71463", "url": "https://www.rhea-db.org/rhea/71463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71471", "url": "https://www.rhea-db.org/rhea/71471", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71475", "url": "https://www.rhea-db.org/rhea/71475", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71483", "url": "https://www.rhea-db.org/rhea/71483", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71487", "url": "https://www.rhea-db.org/rhea/71487", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RC85-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LC15", "url": "https://www.uniprot.org/uniprotkb/I3LC15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LC15-1", "url": "https://www.uniprot.org/uniprotkb/I3LC15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTRWTCPGPSLLVLFCYGQLLPWLRAKVGTMPISFSTDELYSETVAKAFLQFYERTAQVVWNQFMEATWNYVTNITNKNREEMLRKDVERSQHTLYFGTRARLFKIDDFQDPDVKRMLSKLQNLYKAALPEDELREYNQILAYMETTYSMAQVCLNEGPCLPLEPDLEEVMATSRDQKELLWAWQGWRDAVGRQLRMTFERYVQLSNKAAELNGYEDMGAMWRSAYESDTLEQDVEQLYEELQPLYLNLHAYVRRGLYRFYGPQLIDPRGPIPAHILGNMWAQSWVSILDLVLPFPEKPPEDITKIMKGQHWKPEKMFQEAEKFFTSLGLLSTPPEFWKNSMMERPTDGREVECHASAWDFYNGEDFRIKKCTEVTIEDLLSIFHQMGHIQYFLQYKNLSVIFRAGANPAFEEAVGSVITLSASSHKHLLNRGLLSHQHQDEEEEVNFLMSMALEKIAFIPFAYLVDRFRWKVFDGTIRKAVYNQEWWNLRLKYQGLCPPVPRTEDDFDPGAKFHISASMPYIRYFLSLMLQFQIHEALCKASGHVGPLHRCDIYNSKKAGKLLADVLKLGSSKPWPEVLQKITGETKVSTKALMTYFKPLLNWLVTENVRHGEILGWPDFSCSLEQSFDKETDRAAFLGLELNPDQAKSGQWVLLALSFVMLLMVLLLAYKVYTLEKKSLDTSTRDNSVHVPPPKAYFLGTAMEPHQVVRRQWMLLGLCLILMLCSVGLIIRIFTQHSWKPPWMRDEWWSWD", "length": 754, "header": "tr|A0A5G2RC85-1|A0A5G2RC85_PIG Isoform 1 of Angiotensin-converting enzyme OS=Sus scrofa OX=9823 GN=LOC100515049 PE=3 SV=2 CANONICAL=A0A5G2RC85-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RC85-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85/entry#A0A5G2RC85-1", "sequence": { "sequence": "MGTRWTCPGPSLLVLFCYGQLLPWLRAKVGTMPISFSTDELYSETVAKAFLQFYERTAQVVWNQFMEATWNYVTNITNKNREEMLRKDVERSQHTLYFGTRARLFKIDDFQDPDVKRMLSKLQNLYKAALPEDELREYNQILAYMETTYSMAQVCLNEGPCLPLEPDLEEVMATSRDQKELLWAWQGWRDAVGRQLRMTFERYVQLSNKAAELNGYEDMGAMWRSAYESDTLEQDVEQLYEELQPLYLNLHAYVRRGLYRFYGPQLIDPRGPIPAHILGNMWAQSWVSILDLVLPFPEKPPEDITKIMKGQHWKPEKMFQEAEKFFTSLGLLSTPPEFWKNSMMERPTDGREVECHASAWDFYNGEDFRIKKCTEVTIEDLLSIFHQMGHIQYFLQYKNLSVIFRAGANPAFEEAVGSVITLSASSHKHLLNRGLLSHQHQDEEEEVNFLMSMALEKIAFIPFAYLVDRFRWKVFDGTIRKAVYNQEWWNLRLKYQGLCPPVPRTEDDFDPGAKFHISASMPYIRYFLSLMLQFQIHEALCKASGHVGPLHRCDIYNSKKAGKLLADVLKLGSSKPWPEVLQKITGETKVSTKALMTYFKPLLNWLVTENVRHGEILGWPDFSCSLEQSFDKETDRAAFLGLELNPDQAKSGQWVLLALSFVMLLMVLLLAYKVYTLEKKSLDTSTRDNSVHVPPPKAYFLGTAMEPHQVVRRQWMLLGLCLILMLCSVGLIIRIFTQHSWKPPWMRDEWWSWD", "length": 754, "header": "tr|A0A5G2RC85-1|A0A5G2RC85_PIG Isoform 1 of Angiotensin-converting enzyme OS=Sus scrofa OX=9823 GN=LOC100515049 PE=3 SV=2 CANONICAL=A0A5G2RC85-1" }, "locus": { "chromosome": "12", "start_pos": 15386741, "end_pos": 15377592, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080724.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080724.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068234.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068234.2" } ] } }, { "isoform_ac": "I3LC15-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85/entry#I3LC15-1", "sequence": { "sequence": "MDLPWTFPTCALLLWAALAMAQGQDELYSETVAKAFLQFYERTAQVVWNQFMEATWNYVTNITNKNREEMLRKDVERSQHTLYFGTRARLFKIDDFQDPDVKRMLSKLQNLYKAALPEDELREYNQILAYMETTYSMAQVCLNEGPCLPLEPDLEEVMATSRDQKELLWAWQGWRDAVGRQLRMTFERYVQLSNKAAELNGYEDMGAMWRSAYESDTLEQDVEQLYEELQPLYLNLHAYVRRGLYRFYGPQLIDPRGPIPAHILGNMWAQSWVSILDLVLPFPEKPPEDITKIMKGQHWKPEKMFQEAEKFFTSLGLLSTPPEFWKNSMMERPTDGREVECHASAWDFYNGEDFRIKKCTEVTIEDLLSIFHQMGHIQYFLQYKNLSVIFRAGANPAFEEAVGSVITLSASSHKHLLNRGLLSHQHQDEEEEVNFLMSMALEKIAFIPFAYLVDRFRWKVFDGTIRKAVYNQEWWNLRLKYQGLCPPVPRTEDDFDPGAKFHISASMPYIRYFLSLMLQFQIHEALCKASGHVGPLHRCDIYNSKKAGKLLADVLKLGSSKPWPEVLQKITGETKVSTKALMTYFKPLLNWLVTENVRHGEILGWPDFSCSLEQSFDKETDRAAFLGLELNPDQAKSGQWVLLALSFVMLLMVLLLAYKVYTLEKKSLAQDTSAQDTSVQDTSTRDNSVHVPPPKAYFLGTAMEPHQVVRRQWMLLGLCLILMLCSVGLIIRIFTQHSWKPPWMRDEWWSWD", "length": 752, "header": "tr|I3LC15-1|A0A5G2RC85_PIG Computationally mapped isoform of Angiotensin-converting enzyme OS=Sus scrofa OX=9823 GN=LOC100515049 PE=3 SV=2 CANONICAL=A0A5G2RC85-1" }, "locus": { "chromosome": "12", "start_pos": 15386730, "end_pos": 15377592, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027986.5", "url": "https://www.ensembl.org/id/ENSSSCT00000027986.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021588.2", "url": "https://www.ensembl.org/id/ENSSSCP00000021588.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 75, "start_aa": "Asn", "end_pos": 75, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn75", "evidence": [ { "id": "A0A5G2RC85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85#ptm_processing" }, { "id": "PIRSR601548-10", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-10" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LC15", "url": "https://www.uniprot.org/uniprotkb/I3LC15" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "M0RB66-1", "protein_name": "Angiotensin-converting enzyme", "gene_name": "Ace3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFPWAFLLVLLYYGQPLPWPKTVGEPSLDEFYSEAQAKMFLQFYEQTARVVLNELMEATWNYVTNITKQNQENMLQKEVERSQFMLYFGTRARMFRIDHFQDLDVKRRLSKLRNIDKSALPVEDFQEFNRLLTYMKTAYGRAEVCLDEGPCMPLEPDLEEIMATSRDQKELLWAWQGWRDAIGRQLRPVFEDYVHLSNKAAQYNGYKDMGALWRSKYESDTLEEDLEQLYKELQPLYLNLHAYVRRSLYRYYGPELIDLRGPIPAHLLGNMWAQSWNNILDLVLPYPNKPPEDITKIMKNQHWRPEKMFEEANLFFTSMGMLPAPPAFWMKSMMEKPVDGREVECHTSSWNFYRLNDFRVKKCTEVTIGDLLSIFHQMGHIQYYLQCQNLSIIYQEGASPAFEEAVGSTITLSAFSHKYLLTRGLLSQQHQDSEEEVNFLLSIALEKIAFIPFGYMIDLFRWKVFDGTIQKNAYNQEWWSLRLKYQGLCPPVPRSEDDFDPGAKFHIPANMPYIRYFLSLVLQFQLHEVLCRASGHVGPLHRCDIYNSKVAGKILGDFLKVGSSRPWQEVLKEITGKPNISTKALLTYFKPLLNWLVTENVKQGDILGWPDFSCSFEEKITKKMSFLGMKIEPDQAYLGQWVLLSMSFIMLCLILALGLRLHYLERRSLDSDTVILSTPPYAYFLGIAMEPRQAARKQWLLLGLCFVLMLCCIGLLIKIFIHHTRKPPWMKAEWQS", "length": 737 }, "evidence": [ { "id": "A0A5G2RC85", "url": "https://omabrowser.org/oma/group/A0A5G2RC85/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VLJ6-1", "protein_name": "Angiotensin-converting enzyme-related protein", "gene_name": "Acer", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGACNITVLLLVIMLWLPHGLSMGNSCSASVLEARRFFELENEQLRRRFHEEFLSGYNYNTNVTEANRQAMIEVYARNAELNKRLAQQIKSSDYVQSEDADIRRQAEHLSKLGASALNADDYLALQNAISSMQTNYATATVCSYTNRSDCSLTLEPHIQERLSHSRDPAELAWYWREWHDKSGTPMRQNFAEYVRLTRKASQLNGHRSYADYWVQFYEDPDFERQLDATFKQLLPFYRQLHGYVRFRLRQHYGPDVMPAEGNIPISLLGNMWGQSWNELLDLFTPYPEKPFVDVKAEMEKQGYTVQKLFELGDQFFQSLGMRALPPSFWNLSVLTRPDDRHVVCHASAWDFYQDSDVRIKMCTEVDSHYFYVVHHELGHIQYYLQYEQQPAVYRGAPNPGFHEAVGDVIALSVMSAKHLKAIGLIENGRLDEKSRINQLFKQALSKIVFLPFGYAVDKYRYAVFRNELDESQWNCGFWQMRSEFGGVEPPVFRTEKDFDPPAKYHIDADVEYLRYFAAHIFQFQFHKALCRKAGQYAPNNSRLTLDNCDIFGSKAAGRSLSQFLSKGNSRHWKEVLEEFTGETEMDPAALLEYFEPLYQWLKQENSRLGVPLGWGPTDKIPSDCCGTFST", "length": 630 }, "evidence": [ { "id": "A0A5G2RC85", "url": "https://omabrowser.org/oma/group/A0A5G2RC85/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ], "pmid": "" }, { "name": "carboxypeptidase activity", "id": "GO:0004180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004180", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ], "pmid": "" }, { "name": "peptidyl-dipeptidase activity", "id": "GO:0008241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008241", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "angiotensin maturation", "id": "GO:0002003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002003", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ], "pmid": "" }, { "name": "positive regulation of systemic arterial blood pressure", "id": "GO:0003084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003084", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RC85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "63560", "name": "", "equation": "angiotensin I + H2O = L-histidyl-L-leucine + angiotensin II", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "63560", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63560" } ] }, { "id": "70675", "name": "", "equation": "Met-enkephalin-Arg-Phe + H2O = L-arginyl-L-phenylalanine + Met-enkephalin", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70675", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70675" } ] }, { "id": "71451", "name": "", "equation": "bradykinin + H2O = L-Phe-L-Arg + bradykinin(1-7)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71451", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71451" } ] }, { "id": "71455", "name": "", "equation": "goralatide + H2O = N-acetyl-L-seryl-L-aspartate + L-lysyl-L-proline", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71455", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71455" } ] }, { "id": "71459", "name": "", "equation": "substance P + H2O = substance P(1-9) + L-Leu-L-Met-NH2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71459", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71459" } ] }, { "id": "71463", "name": "", "equation": "substance P + H2O = substance P(1-8) + Gly-L-Leu-L-Met-NH2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71463" } ] }, { "id": "71471", "name": "", "equation": "substance P + H2O = L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2 + substance P(1-6)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71471", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71471" } ] }, { "id": "71475", "name": "", "equation": "neurotensin + H2O = neurotensin(1-11) + L-isoleucyl-L-leucine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71475", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71475" } ] }, { "id": "71483", "name": "", "equation": "Met-enkephalin + H2O = L-phenylalanyl-L-methionine + L-tyrosylglycylglycine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71483", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71483" } ] }, { "id": "71487", "name": "", "equation": "Leu-enkephalin + H2O = L-tyrosylglycylglycine + L-phenylalanyl-L-leucine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71487", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71487" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RC85-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 754, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RC85-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RC85" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "I3LC15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3LC15#function" }, { "id": "I3LC15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3LC15" }, { "id": "PIRSR601548-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-3" }, { "id": "PIRSR601548-8", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-8" } ], "binding_site_uniprot": 372, "amino_acid": "Lys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 372, "end_pos": 372, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "I3LC15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3LC15#function" }, { "id": "I3LC15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3LC15" }, { "id": "PIRSR601548-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-3" }, { "id": "PIRSR601548-8", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-8" } ], "binding_site_uniprot": 376, "amino_acid": "Val", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 376, "end_pos": 376, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RC85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85#function" }, { "id": "A0A5G2RC85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" }, { "id": "PIRSR601548-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-3" }, { "id": "PIRSR601548-8", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-8" } ], "binding_site_uniprot": 386, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 386, "end_pos": 386, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RC85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85#function" }, { "id": "A0A5G2RC85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" }, { "id": "PIRSR601548-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-3" }, { "id": "PIRSR601548-8", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-8" } ], "binding_site_uniprot": 390, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 390, "end_pos": 390, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "I3LC15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3LC15#function" }, { "id": "I3LC15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3LC15" }, { "id": "PIRSR601548-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-3" }, { "id": "PIRSR601548-8", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-8" } ], "binding_site_uniprot": 400, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 400, "end_pos": 400, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RC85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85#function" }, { "id": "A0A5G2RC85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC85" }, { "id": "PIRSR601548-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-3" }, { "id": "PIRSR601548-8", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601548-8" } ], "binding_site_uniprot": 414, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 414, "end_pos": 414, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 75 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 399, "end_pos": 401 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RCB7-1", "uniprot_ac": "A0A5G2RCB7", "uniprot_id": "A0A5G2RCB7_PIG", "mass": { "chemical_mass": 44835.0, "monoisotopic_mass": 44835.0 }, "refseq": { "ac": "XP_020936627", "name": "heat shock transcription factor, Y-linked-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936627" }, "gene_names": [ { "name": "LOC110257950", "type": "synonym", "evidence": [ { "id": "XP_020936627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936627" } ] } ], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RCB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB7/entry#names_and_taxonomy" } ] }, { "name": "heat shock transcription factor, Y-linked-like", "type": "synonym", "evidence": [ { "id": "XP_020936627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936627" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB7", "locus": {} } ], "crossref": [ { "id": "A0A5G2RCB7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCB7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041211", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041211", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110257950", "url": "https://www.ncbi.nlm.nih.gov/gene/110257950", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110257950", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257950", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RCB7", "url": "https://www.orthodb.org/?gene=A0A5G2RCB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020936627", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936627", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RCB7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHASSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQVEEKAFQALSEGSLMKEPCHTLCAPEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNGSPVSASLLQGCSKKRSRTGGDVDNHNSDVVAETRGEDAFSTSTNLNVPLIGWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHALFSQLTTFHMHSQSSYSPASGHVVNFITTTTSISQYRCISNFPSGYFGLRVEPSPLPTRYQNISPTESPLSNPQPAALPWFPMPMATDTSAASLSRPNHQSFSVSEHHPNFH", "length": 402, "header": "tr|A0A5G2RCB7-1|A0A5G2RCB7_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RCB7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RCB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB7/entry#A0A5G2RCB7-1", "sequence": { "sequence": "MAHASSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQVEEKAFQALSEGSLMKEPCHTLCAPEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNGSPVSASLLQGCSKKRSRTGGDVDNHNSDVVAETRGEDAFSTSTNLNVPLIGWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHALFSQLTTFHMHSQSSYSPASGHVVNFITTTTSISQYRCISNFPSGYFGLRVEPSPLPTRYQNISPTESPLSNPQPAALPWFPMPMATDTSAASLSRPNHQSFSVSEHHPNFH", "length": 402, "header": "tr|A0A5G2RCB7-1|A0A5G2RCB7_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RCB7-1" }, "locus": { "chromosome": "Y", "start_pos": 20261265, "end_pos": 20259637, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067283.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067283.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071877.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071877.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 356, "start_aa": "Thr", "end_pos": 356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr356", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "ssc:110257950", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257950", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCB7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RCB7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RCB7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCB7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RCB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCB7" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 356 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2RCH4-1", "uniprot_ac": "A0A5G2RCH4", "uniprot_id": "A0A5G2RCH4_PIG", "mass": { "chemical_mass": 35658.0, "monoisotopic_mass": 35658.0 }, "refseq": { "ac": "XP_020941148", "name": "olfactory receptor 2L8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941148" }, "gene_names": [ { "name": "LOC100523232", "type": "recommended", "evidence": [ { "id": "A0A5G2RCH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4" } ] }, { "name": "LOC100523232", "type": "synonym", "evidence": [ { "id": "XP_020941148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941148" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RCH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2L8", "type": "synonym", "evidence": [ { "id": "XP_020941148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941148" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100523232", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4", "locus": {} } ], "crossref": [ { "id": "A0A5G2RCH4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523232", "url": "https://www.ncbi.nlm.nih.gov/gene/100523232", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523232", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523232", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ssc:110255197", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255197", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VYRMHSR", "url": "https://omabrowser.org/oma/group/VYRMHSR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RCH4", "url": "https://www.orthodb.org/?gene=A0A5G2RCH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020941148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941148", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RCH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENYNQTSTDFILLGLFPPSRIGLFLFILVVLIFLMALFGNLSMILLIFMDIHLHKPMYFLLSQLSLIDLNYISTIVPKMAYNFLFGNKSISFIGCGVQSFFFLTLAGAEALLLASMAYDRYVAICFPLHYSIRISRRVCVLMITASWIMGSINSCAHTTYALHIHYCRSRAINHFFCDVPAMLTLACMDTWIYEYTVFVSTILFLLLPFIGIACSYGRVLLAVYHMNSAEGKKKAYSTCSTHLTVVTFYYVPFVYTYLRPRDLRSPTEDKALAVFYTILTPMLNPVIYSLKNKEVMGALKRVIQRIFSVKV", "length": 312, "header": "tr|A0A5G2RCH4-1|A0A5G2RCH4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100523232 PE=3 SV=1 CANONICAL=A0A5G2RCH4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RCH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4/entry#A0A5G2RCH4-1", "sequence": { "sequence": "MENYNQTSTDFILLGLFPPSRIGLFLFILVVLIFLMALFGNLSMILLIFMDIHLHKPMYFLLSQLSLIDLNYISTIVPKMAYNFLFGNKSISFIGCGVQSFFFLTLAGAEALLLASMAYDRYVAICFPLHYSIRISRRVCVLMITASWIMGSINSCAHTTYALHIHYCRSRAINHFFCDVPAMLTLACMDTWIYEYTVFVSTILFLLLPFIGIACSYGRVLLAVYHMNSAEGKKKAYSTCSTHLTVVTFYYVPFVYTYLRPRDLRSPTEDKALAVFYTILTPMLNPVIYSLKNKEVMGALKRVIQRIFSVKV", "length": 312, "header": "tr|A0A5G2RCH4-1|A0A5G2RCH4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100523232 PE=3 SV=1 CANONICAL=A0A5G2RCH4-1" }, "locus": { "chromosome": "2", "start_pos": 54998498, "end_pos": 54997563, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084639.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084639.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071952.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071952.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523232", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523232", "resource": "KEGG Pathway" }, { "id": "ssc:110255197", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255197", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RCH4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RCH4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCH4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RCH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCH4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RCJ8-1", "uniprot_ac": "A0A5G2RCJ8", "uniprot_id": "A0A5G2RCJ8_PIG", "mass": { "chemical_mass": 60648.0, "monoisotopic_mass": 60648.0 }, "refseq": { "ac": "XP_013848413", "name": "LOW QUALITY PROTEIN: meiosis-specific nuclear structural protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013848413" }, "gene_names": [ { "name": "MNS1", "type": "recommended", "evidence": [ { "id": "A0A5G2RCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ] }, { "name": "MNS1", "type": "synonym", "evidence": [ { "id": "XP_013848413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013848413" } ] } ], "protein_names": [ { "name": "Meiosis-specific nuclear structural protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2RCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: meiosis-specific nuclear structural protein 1", "type": "synonym", "evidence": [ { "id": "XP_013848413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013848413" } ] } ], "function": [ { "annotation": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis. Required for sperm flagella assembly. May play a role in the assembly and function of the outer dynein arm-docking complex (ODA-DC). ODA-DC mediates outer dynein arms (ODA) binding onto the axonemal doublet microtubules.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8#function" }, { "database": "UniProtKB", "id": "ARBA00046114", "url": "https://www.uniprot.org/uniprotkb/ARBA00046114#function" }, { "database": "UniProtKB", "id": "F1RZG8", "url": "https://www.uniprot.org/uniprotkb/F1RZG8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MNS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8", "locus": { "chromosome": "1", "start_pos": 115553524, "end_pos": 115471922, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004601", "url": "https://www.ensembl.org/id/ENSSSCG00000004601" } ] } } ], "crossref": [ { "id": "A0A5G2RCJ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCJ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004601", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004601", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100621861", "url": "https://www.ncbi.nlm.nih.gov/gene/100621861", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "9CPC", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CPC&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR026504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621861", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621861", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QIRNQMV", "url": "https://omabrowser.org/oma/group/QIRNQMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RCJ8", "url": "https://www.orthodb.org/?gene=A0A5G2RCJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19265", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19265", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19265:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19265:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00009cpc", "url": "https://www.rcsb.org/structure/pdb_00009cpc", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CPC", "url": "https://www.rcsb.org/structure/9CPC", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF13868", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13868", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013848413", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013848413", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZG8", "url": "https://www.uniprot.org/uniprotkb/F1RZG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZG8-1", "url": "https://www.uniprot.org/uniprotkb/F1RZG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKRRTLSFSERHQKLVDANYCKKLHVEALKKLQNQVRNQMVRNENDDRAEHKRFLRLLQNEQFELDMEEAIQKAEENRRLRECQLEQEEKLALELAKLKHESLKDEKMRQQVRENSIELRELEKKLQAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHERLIKEENATEDKRNKVKAQYNLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLERQQKLEKMKTTQRYIEEFKKQQAVWRKKKREEMEEENRRIIEFAKMQQQREEDWMAKVQETEEKRLQLQNTLSQRLEEMLRQREDLEQVRQELYLEEQAEIHKKKLEEEAEKKLRKQKELKQNFMEQMALKELVLQAAKEEEEIFRKAMLAKYAEDDRIELMNAQKQRMKQLEHKKAVEKLIEERRNQFLADKQRELEEWQLQQRRQGCVNEIIEEERLKLLKEHATKLLGYLPKGVFKKVDDIDMLGEEFRKAYQKRSEICEHK", "length": 495, "header": "tr|A0A5G2RCJ8-1|A0A5G2RCJ8_PIG Isoform 1 of Meiosis-specific nuclear structural protein 1 OS=Sus scrofa OX=9823 GN=MNS1 PE=1 SV=1 CANONICAL=A0A5G2RCJ8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RCJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8/entry#A0A5G2RCJ8-1", "sequence": { "sequence": "MASKRRTLSFSERHQKLVDANYCKKLHVEALKKLQNQVRNQMVRNENDDRAEHKRFLRLLQNEQFELDMEEAIQKAEENRRLRECQLEQEEKLALELAKLKHESLKDEKMRQQVRENSIELRELEKKLQAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHERLIKEENATEDKRNKVKAQYNLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLERQQKLEKMKTTQRYIEEFKKQQAVWRKKKREEMEEENRRIIEFAKMQQQREEDWMAKVQETEEKRLQLQNTLSQRLEEMLRQREDLEQVRQELYLEEQAEIHKKKLEEEAEKKLRKQKELKQNFMEQMALKELVLQAAKEEEEIFRKAMLAKYAEDDRIELMNAQKQRMKQLEHKKAVEKLIEERRNQFLADKQRELEEWQLQQRRQGCVNEIIEEERLKLLKEHATKLLGYLPKGVFKKVDDIDMLGEEFRKAYQKRSEICEHK", "length": 495, "header": "tr|A0A5G2RCJ8-1|A0A5G2RCJ8_PIG Isoform 1 of Meiosis-specific nuclear structural protein 1 OS=Sus scrofa OX=9823 GN=MNS1 PE=1 SV=1 CANONICAL=A0A5G2RCJ8-1" }, "locus": { "chromosome": "1", "start_pos": 115526177, "end_pos": 115472055, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072426.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072426.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071982.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071982.1" } ] } }, { "isoform_ac": "F1RZG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8/entry#F1RZG8-1", "sequence": { "sequence": "MASKRRTLSFSERHQKLVDANYCKKLHVEALKKLQNQVRNQMVRNENDDRAEHKRFLRLLQNEQFELDMEEAIQKAEENRRLRECQLEQEEKLALELAKLKHESLKDEKMRQQVRENSIELRELEKKLQAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHERLIKEENATEDKRNKVKAQYNLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLERQQKLEKMKTTQRYIEEFKKQQAVWRKKKREEMEEENRRIIEFAKMQQQREEDWMAKVQETEEKRLQLQNTLSQRLEEMLRQREDLEQVRQELYLEEQAEIHKKKLEEEAEKKLRKQKELKQNFMEQMALKELVLQAAKEEEEIFRKAMLAKYAEDDRIELMNAQKQRMKQLEHKKAVEKLIEERRNQFLADKQRELEEWQLQQRRQGCVNEIIEEERLKLLKEHATKLLGYLPKGVFKKVDDIDMLGEEFRKAYQKKE", "length": 489, "header": "tr|F1RZG8-1|A0A5G2RCJ8_PIG Computationally mapped isoform of Meiosis-specific nuclear structural protein 1 OS=Sus scrofa OX=9823 GN=MNS1 PE=1 SV=3 CANONICAL=A0A5G2RCJ8-1" }, "locus": { "chromosome": "1", "start_pos": 115526158, "end_pos": 115472055, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005082.4", "url": "https://www.ensembl.org/id/ENSSSCT00000005082.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004958.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004958.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Structural diversity of axonemes across mammalian motile cilia.", "journal": "Nature", "date": "2025", "authors": "Leung Miguel Ricardo, Sun Chen, Zeng Jianwei, Anderson Jacob R, Niu Qingwei, Huang Wei, Noteborn Willem E M, Brown Alan, Zeev-Ben-Mordehai Tzviya, Zhang Rui", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "reference": [ { "type": "PubMed", "id": "39743588", "url": "https://glygen.org/publication/PubMed/39743588" } ] } ], "pathway": [ { "id": "ssc:100621861", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621861", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZU07-1", "protein_name": "Meiosis-specific nuclear structural protein 1", "gene_name": "MNS1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MREFSGCISSMRYKRAAAHLKRVAKLRPPRPGAEPAAELLRGGSAPHTALSGALSALSPSADRKSPQGEEQRQQRERRRLQEERLAAELARLKHEELSDEKMRQQVRENSIELRELEKKLKSAYLNKERAAQIAEKEAMQYEKMKREAEIAQKMKEEHERAAKEESLAELRQNEEKIMYQQELEKQLEEQERKKQGVYEEFLKEKLMIDEIIRKIYEEDQMEKQLKLEKMRAIQTYIEEFKKEQAVWRQRKREEMEEENRRIVEFANNQRQREEDRMAKVRDMEEKKQRLQAMIAQNLEREQQKRDELERIRQELYLEEQLETDRKKEMAEIEKRIRQRLDLRQMYEEQFALKKIAQQAVQEEEEAFRQQMQAKFAEDDRVEQMNAQKRRMKQLEHRKAVEKLIEDRHKQFIADKERELEEWQLEEKRQANIRAVVEEERQKLLKEHASKLLGYLPRGVLKGEDDINMLGEEFRLAYQKRRGNPSSEES", "length": 489 }, "evidence": [ { "id": "A0A5G2RCJ8", "url": "https://omabrowser.org/oma/group/A0A5G2RCJ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GRL2-1", "protein_name": "Meiosis-specific nuclear structural protein 1", "gene_name": "Mns1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATRRRAMSFSEKHQKLVDENFRKSLHVQVLNKLERQTKNQVVKNQNDERVERKRFLRVLQNEQFELDMEEAIQKAAENKMLKDRQLEQEERLANELARLKHESLKDEKMRQQVRENSMELRELEQKLQAAYMNKERAAQIAEKDAIKYEQMRRDAEIARVMMEEHERVKKEESVKQDRRNKEKAQYHLDLEKQLEEQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQLERQQKLEKMNATQKYIEAFQREQELWRQKKREEMEEENRKIIEFMNIQQQREEERVARVQESEEKRAQRQNLLIQKLEERLRKQEDLEQVRQELYQEEQAEMLKLKLKEEVEQKLQRQREMKQDLEDQIALKEIILQATKEEEETFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEELQLQQRQQGCINKIIEEERLKLLKEHATKLLGYLPKGVFKREDDVDMLGEDFRKAYQKKE", "length": 489 }, "evidence": [ { "id": "A0A5G2RCJ8", "url": "https://omabrowser.org/oma/group/A0A5G2RCJ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q61884-1", "protein_name": "Meiosis-specific nuclear structural protein 1", "gene_name": "Mns1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATKKRALSFSEKHQKLVDEKFRKSLNIQVMNKLERQAKNQVVQNENDEKVERQRFLRVLQNEQFELDMEEAIQKAEANKMLRDRQLEQEERLANELARLKHESLKDKKMRQQVRENSIELRELEQKLKAAYMNKERAAQIVEKDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNKERAQYYLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQRAQDFWRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQDFEDQMALKELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEELQLQQRRQGCINEIIEEERLRLLKEHAAKLLGYLPKGVFKREDDVDMLGEEFRKAYQKRDGV", "length": 491 }, "evidence": [ { "id": "A0A5G2RCJ8", "url": "https://omabrowser.org/oma/group/A0A5G2RCJ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6AXQ8-1", "protein_name": "Meiosis-specific nuclear structural protein 1", "gene_name": "Mns1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANKKRAMSFSEKHQQLVDENFRKSLHVQVLNKLERQAKNQVVQNENDERVERQRFLRVLQNEQFELDMEEAVQKAEENKRMRDRQLEQEERLANELARLKHESLKDEKMRQQVRENSIELRELEQKLKAAYMNKERAAQIVEKDVIKYEQMKRDAEIERIMMEEHKRLLKEENVKQEKRDKERAQYYVDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQLERQQKLEKRNAIQKYIKEFQRAQDLWRQKKREEMEEENRKILEFAKIQEQREGERMARVQESEEKRVQRQNLLIQKLEETLRQRDDLERVRQELYLEEYAEFIKLKMKEEVEQRLRKQRDRKQDFKDQMALREVLLQAAKEEEEAFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRNQFLADKQRELEELQLQQRRQGCINEIIEEERLRLLKEHASKLLGYLPKGVFKKEDDVDMLGEEFRKAYQKKSEVCEEKGSS", "length": 498 }, "evidence": [ { "id": "A0A5G2RCJ8", "url": "https://omabrowser.org/oma/group/A0A5G2RCJ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NEH6-1", "protein_name": "Meiosis-specific nuclear structural protein 1", "gene_name": "MNS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSKRRNLSCSERHQKLVDENYCKKLHVQALKNVNSQIRNQMVQNENDNRVQRKQFLRLLQNEQFELDMEEAIQKAEENKRLKELQLKQEEKLAMELAKLKHESLKDEKMRQQVRENSIELRELEKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKRIIKEENAAEDKRNKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKREEMEEENRKIIEFANMQQQREEDRMAKVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQELYQEEQAEIYKSKLKEEAEKKLRKQKEMKQDFEEQMALKELVLQAAKEEEENFRKTMLAKFAEDDRIELMNAQKQRMKQLEHRRAVEKLIEERRQQFLADKQRELEEWQLQQRRQGFINAIIEEERLKLLKEHATNLLGYLPKGVFKKEDDIDLLGEEFRKVYQQRSEICEEK", "length": 495 }, "evidence": [ { "id": "A0A5G2RCJ8", "url": "https://omabrowser.org/oma/group/A0A5G2RCJ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "pmid": "" }, { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "pmid": "" }, { "name": "axonemal A tubule inner sheath", "id": "GO:0160111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160111", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "pmid": "" }, { "name": "positive regulation of cilium assembly", "id": "GO:0045724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045724", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RCJ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 495, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RCJ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCJ8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCJ8" }, { "id": "PF13868", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13868" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Trichohyalin-plectin-homology", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 465, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RCM5-1", "uniprot_ac": "A0A5G2RCM5", "uniprot_id": "A0A5G2RCM5_PIG", "mass": { "chemical_mass": 34962.0, "monoisotopic_mass": 34962.0 }, "refseq": { "ac": "XP_003129496", "name": "olfactory receptor 52H1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129496" }, "gene_names": [ { "name": "LOC100516817", "type": "synonym", "evidence": [ { "id": "XP_003129496", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129496" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 52H1-like", "type": "synonym", "evidence": [ { "id": "XP_003129496", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129496" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5", "locus": {} } ], "crossref": [ { "id": "A0A5G2RCM5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15221", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15221", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100516817", "url": "https://www.ncbi.nlm.nih.gov/gene/100516817", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516817", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516817", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RCM5", "url": "https://www.orthodb.org/?gene=A0A5G2RCM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003129496", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129496", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RCM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVDNLTGPNTASFTLLGIPGLEPYHVWISIPFCLIYLVAIVGNSILLYLIAVEHSLHAPMFFFLAMLAVTDLVLSTTCVPKTLSIFWLGPQKISFPGCLTQLFFLHYSFVLDSAILMAMAFDRYVAICSPLRYTTILTPKTTVKMAVGIFLRSFCVIVPCVFLAHRLPFCGTRAIPHTYCEHIGVARLACADIAVNIWYGFCVPIMTVVSDVVLIAVSYVLILCAVFRLPSQEARQKALGTCGSHVCVILMFYIPAFFSILAHRFGQNVPRGFHIVFANLYVIIPPALNPAVYGVKTKQIRDKVILLLFPKKSY", "length": 315, "header": "tr|A0A5G2RCM5-1|A0A5G2RCM5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RCM5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RCM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5/entry#A0A5G2RCM5-1", "sequence": { "sequence": "MAVDNLTGPNTASFTLLGIPGLEPYHVWISIPFCLIYLVAIVGNSILLYLIAVEHSLHAPMFFFLAMLAVTDLVLSTTCVPKTLSIFWLGPQKISFPGCLTQLFFLHYSFVLDSAILMAMAFDRYVAICSPLRYTTILTPKTTVKMAVGIFLRSFCVIVPCVFLAHRLPFCGTRAIPHTYCEHIGVARLACADIAVNIWYGFCVPIMTVVSDVVLIAVSYVLILCAVFRLPSQEARQKALGTCGSHVCVILMFYIPAFFSILAHRFGQNVPRGFHIVFANLYVIIPPALNPAVYGVKTKQIRDKVILLLFPKKSY", "length": 315, "header": "tr|A0A5G2RCM5-1|A0A5G2RCM5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RCM5-1" }, "locus": { "chromosome": "9", "start_pos": 4259383, "end_pos": 4258439, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073140.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073140.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072017.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072017.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516817", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516817", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RCM5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 315, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RCM5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCM5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 294, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RCQ8-1", "uniprot_ac": "A0A5G2RCQ8", "uniprot_id": "A0A5G2RCQ8_PIG", "mass": { "chemical_mass": 32877.0, "monoisotopic_mass": 32877.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RCQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8", "locus": {} } ], "crossref": [ { "id": "A0A5G2RCQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000042947", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042947", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RCQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSAAYGSNNYTAVTEFILLGLTDRPELQPLLFVVFLVIYLITVIGNVSMILLIRSDSKLHTPMYFFLSHLAFVDLCYTTTVTPQMLVHFLSKRKTISFLGCFIQFHFIIALVITDYYLLTVMAYDRYMAIGKPLLYGSKMSQSVCLALVATPYIYGFANGLAQTILMLRLSFCGPNEISHFYCADPPLLVLACSDMYVKETAMFVVAGFNLTCSLTIILIPYIFIFTAFSTCGSHLTAVTVFYGTLFWEIVAVFYIFVSPMVNPLIYSLRNKDVKGAIRRMFQRKLFVI", "length": 291, "header": "tr|A0A5G2RCQ8-1|A0A5G2RCQ8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RCQ8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RCQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8/entry#A0A5G2RCQ8-1", "sequence": { "sequence": "MAVSAAYGSNNYTAVTEFILLGLTDRPELQPLLFVVFLVIYLITVIGNVSMILLIRSDSKLHTPMYFFLSHLAFVDLCYTTTVTPQMLVHFLSKRKTISFLGCFIQFHFIIALVITDYYLLTVMAYDRYMAIGKPLLYGSKMSQSVCLALVATPYIYGFANGLAQTILMLRLSFCGPNEISHFYCADPPLLVLACSDMYVKETAMFVVAGFNLTCSLTIILIPYIFIFTAFSTCGSHLTAVTVFYGTLFWEIVAVFYIFVSPMVNPLIYSLRNKDVKGAIRRMFQRKLFVI", "length": 291, "header": "tr|A0A5G2RCQ8-1|A0A5G2RCQ8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RCQ8-1" }, "locus": { "chromosome": "AEMK02000449.1", "start_pos": 829757, "end_pos": 828498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075762.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075762.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072057.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072057.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RCQ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 291, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RCQ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCQ8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RCQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCQ8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 291, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 48, "end_pos": 50 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RCR7-1", "uniprot_ac": "A0A5G2RCR7", "uniprot_id": "A0A5G2RCR7_PIG", "mass": { "chemical_mass": 33862.0, "monoisotopic_mass": 33862.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RCR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCR7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCR7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCR7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCR7", "locus": {} } ], "crossref": [ { "id": "A0A5G2RCR7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000043037", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000043037", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RCR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QIRKPMDGANHSVVSEFVFLGLTNSWEIQLILFVFTSTFYVASMMGNSLILLTVTSDPHLHSPMYFLLANLSFLDLGAASVASPKMVYDLFRKRKVISFSGCITQTFFIHVIGGVEGVVLLAMAFDRYVAICKPLHYLTIMSPRMCISFLVAAWMTGLIHSTVQLAFVVNLPFCGPNVLDSFYCDLPRLLKLACTDTYQLESMVMANSGFISVGFFFVVIISYIVIILTVQKHSSAGSSKALSTLSAHITVVVLAFGPFIFFLAIFDSVLTPFLNPVIYTFKNQEMKVAMKRVCRQLVSYRKIS", "length": 304, "header": "tr|A0A5G2RCR7-1|A0A5G2RCR7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RCR7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RCR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCR7/entry#A0A5G2RCR7-1", "sequence": { "sequence": "QIRKPMDGANHSVVSEFVFLGLTNSWEIQLILFVFTSTFYVASMMGNSLILLTVTSDPHLHSPMYFLLANLSFLDLGAASVASPKMVYDLFRKRKVISFSGCITQTFFIHVIGGVEGVVLLAMAFDRYVAICKPLHYLTIMSPRMCISFLVAAWMTGLIHSTVQLAFVVNLPFCGPNVLDSFYCDLPRLLKLACTDTYQLESMVMANSGFISVGFFFVVIISYIVIILTVQKHSSAGSSKALSTLSAHITVVVLAFGPFIFFLAIFDSVLTPFLNPVIYTFKNQEMKVAMKRVCRQLVSYRKIS", "length": 304, "header": "tr|A0A5G2RCR7-1|A0A5G2RCR7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RCR7-1" }, "locus": { "chromosome": "AEMK02000661.1", "start_pos": 45620, "end_pos": 44181, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067766.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067766.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074221.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074221.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCR7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCR7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCR7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RCR7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 304, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RCR7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCR7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RCR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCR7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 262, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RCY6-1", "uniprot_ac": "A0A5G2RCY6", "uniprot_id": "A0A5G2RCY6_PIG", "mass": { "chemical_mass": 34745.0, "monoisotopic_mass": 34745.0 }, "refseq": { "ac": "XP_013850054", "name": "olfactory receptor 2T8-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850054" }, "gene_names": [ { "name": "LOC100626564", "type": "recommended", "evidence": [ { "id": "A0A5G2RCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6" } ] }, { "name": "LOC100626564", "type": "synonym", "evidence": [ { "id": "XP_013850054", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850054" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2T8-like", "type": "synonym", "evidence": [ { "id": "XP_013850054", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850054" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100626564", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6", "locus": {} } ], "crossref": [ { "id": "A0A5G2RCY6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCY6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626564", "url": "https://www.ncbi.nlm.nih.gov/gene/100626564", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626564", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626564", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDQCAAL", "url": "https://omabrowser.org/oma/group/MDQCAAL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RCY6", "url": "https://www.orthodb.org/?gene=A0A5G2RCY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013850054", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850054", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RCY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENWNLTSDFILLGLFNHTGPHLFLFVMVLTTAFTSLVGNALMLLLILLDPQLHRPMYFLLSQLSLMDMMLVSTVVPKMAADYFTGRNSISPAGCGLQIFFFLTLEGGECFLLAAMSYDRYVAICHPLRYPVLMTWPLCLRMILGSWFLGAADGLMQAAATLTFSYCNSHEVDHFFCEAPSLVRLACADTSLFEYAMYVCCVLMLLVPISLILISYSLILSTVLQMHSKNARKKAFATCSSHLSVVGLFFGAAIFTYMRPKSYRSANHDKIVSAFYTIFTPVLNPLIYSLRNSEVKGALRKCIDQCAALKS", "length": 311, "header": "tr|A0A5G2RCY6-1|A0A5G2RCY6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100626564 PE=3 SV=1 CANONICAL=A0A5G2RCY6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RCY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6/entry#A0A5G2RCY6-1", "sequence": { "sequence": "MENWNLTSDFILLGLFNHTGPHLFLFVMVLTTAFTSLVGNALMLLLILLDPQLHRPMYFLLSQLSLMDMMLVSTVVPKMAADYFTGRNSISPAGCGLQIFFFLTLEGGECFLLAAMSYDRYVAICHPLRYPVLMTWPLCLRMILGSWFLGAADGLMQAAATLTFSYCNSHEVDHFFCEAPSLVRLACADTSLFEYAMYVCCVLMLLVPISLILISYSLILSTVLQMHSKNARKKAFATCSSHLSVVGLFFGAAIFTYMRPKSYRSANHDKIVSAFYTIFTPVLNPLIYSLRNSEVKGALRKCIDQCAALKS", "length": 311, "header": "tr|A0A5G2RCY6-1|A0A5G2RCY6_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100626564 PE=3 SV=1 CANONICAL=A0A5G2RCY6-1" }, "locus": { "chromosome": "2", "start_pos": 55660492, "end_pos": 55659560, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082492.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082492.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074311.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074311.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626564", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626564", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NH00-1", "protein_name": "Olfactory receptor 2T8", "gene_name": "OR2T8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENGSYTSYFILLGLFNHTRAHQVLFMMVLSIVLTSLFGNSLMILLIHWDHRLHTPMYFLLSQLSLMDVMLVSTTVPKMAADYLTGSKAISRAGCGAQIFFLPTLGGGECFLLAAMAYDRYAAVCHPLRYPTLMSWQLCLRMNLSCWLLGAADGLLQAVATLSFPYCGAHEIDHFFCETPVLVRLACADTSVFENAMYICCVLMLLVPFSLILSSYGLILAAVLHMRSTEARKKAFATCSSHVAVVGLFYGAAIFTYMRPKSHRSTNHDKVVSAFYTMFTPLLNPLIYSVKNSEVKGALTRCMGRCVALSRE", "length": 312 }, "evidence": [ { "id": "A0A5G2RCY6", "url": "https://omabrowser.org/oma/group/A0A5G2RCY6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "G3N1D7-1", "protein_name": "Olfactory receptor", "gene_name": "OR2T13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MENWNTTSDFILLGLLNHTGAHQFLFVLVLITAFTSFVGNALMFLLILLDSGLHRPMYFLLSQLSLMDMILVITIVPKMAADYLTGRMFISQVGCGFQIFFFLTLEGGECFLLAAMSYDRYVAICHPLRYPVLMSWQLCLRMTLGSWFLGAADGLMQAAATLNFSFCRTHEIDHFFCEAPSLVRLACADTSVFEYAMYVCCVLMLLVPISLILISYSLILAAVLQMCSNEARKKAFTTCSSHISVVGLFFGAAIFTYMRPKSFRSANHDKIVSAFYTIFTPVLNPLIYSLRNSEVKGALRKCMDQCAALSHD", "length": 312 }, "evidence": [ { "id": "A0A5G2RCY6", "url": "https://omabrowser.org/oma/group/A0A5G2RCY6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RCY6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RCY6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCY6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 17, "end_pos": 19 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RCY7-1", "uniprot_ac": "A0A5G2RCY7", "uniprot_id": "A0A5G2RCY7_PIG", "mass": { "chemical_mass": 35056.0, "monoisotopic_mass": 35056.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY7", "locus": {} } ], "crossref": [ { "id": "A0A5G2RCY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242:SF369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242:SF369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RCY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFFKATSNMEICCSFAALKTNKCSHLKNCSSSVSKFILLGFPYTWGIQILLFSIFSGIYILTLIGNRCIICAVRWDPQLQTPMYILLASFSFLEIWFITSTVPNMLANILSETKIISFSGCFLQFYFFFSLGTTETFFLSVMAFDRYLAICRPLHYPTVMTIQRCIRMGTCCCACGFLYFPLPIYLISQLPFCCLNKIDQFICDPGPLIQLLCVAAPAIEIICAIYNSVLIFSTLIFITSSYTLVIRAVLRVPSAEEWCKTFSTCSSHLAAVSLFYGSLMVVYVIPTAGSAAGKQKYVTVLFCVNSISQPLDL", "length": 313, "header": "tr|A0A5G2RCY7-1|A0A5G2RCY7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RCY7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RCY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY7/entry#A0A5G2RCY7-1", "sequence": { "sequence": "MFFKATSNMEICCSFAALKTNKCSHLKNCSSSVSKFILLGFPYTWGIQILLFSIFSGIYILTLIGNRCIICAVRWDPQLQTPMYILLASFSFLEIWFITSTVPNMLANILSETKIISFSGCFLQFYFFFSLGTTETFFLSVMAFDRYLAICRPLHYPTVMTIQRCIRMGTCCCACGFLYFPLPIYLISQLPFCCLNKIDQFICDPGPLIQLLCVAAPAIEIICAIYNSVLIFSTLIFITSSYTLVIRAVLRVPSAEEWCKTFSTCSSHLAAVSLFYGSLMVVYVIPTAGSAAGKQKYVTVLFCVNSISQPLDL", "length": 313, "header": "tr|A0A5G2RCY7-1|A0A5G2RCY7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RCY7-1" }, "locus": { "chromosome": "AEMK02000410.1", "start_pos": 136889, "end_pos": 135951, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067569.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067569.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068549.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068549.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCY7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RCY7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RCY7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RCY7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCY7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 313, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 28, "end_pos": 30 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RD02-1", "uniprot_ac": "A0A5G2RD02", "uniprot_id": "A0A5G2RD02_PIG", "mass": { "chemical_mass": 18565.0, "monoisotopic_mass": 18565.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "exodeoxyribonuclease III", "type": "recommended", "evidence": [ { "id": "A0A5G2RD02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02/entry#names_and_taxonomy" } ] }, { "name": "3.1.11.2", "type": "synonym", "evidence": [ { "id": "A0A5G2RD02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02", "locus": {} } ], "crossref": [ { "id": "A0A5G2RD02", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RD02", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044211", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044211", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09076", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09076", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22748", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22748", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22748:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22748:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RD02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RD02-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAIRTYIAIITLNVNGLNAPNKRHRLAEWIQKQDPYICCFQETHFTSRDTYKLKVRGWKKIFHANRDLKKAGAAILISDKIDFKMKNILRDKEGHYIMIKGSIQEDDITILNIYAPNTGSPQYIRQLLTTLKGEIDNNTIIVGDFNTPLTAMDQIIQTENQ", "length": 161, "header": "tr|A0A5G2RD02-1|A0A5G2RD02_PIG Isoform 1 of exodeoxyribonuclease III OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RD02-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RD02-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02/entry#A0A5G2RD02-1", "sequence": { "sequence": "MAIRTYIAIITLNVNGLNAPNKRHRLAEWIQKQDPYICCFQETHFTSRDTYKLKVRGWKKIFHANRDLKKAGAAILISDKIDFKMKNILRDKEGHYIMIKGSIQEDDITILNIYAPNTGSPQYIRQLLTTLKGEIDNNTIIVGDFNTPLTAMDQIIQTENQ", "length": 161, "header": "tr|A0A5G2RD02-1|A0A5G2RD02_PIG Isoform 1 of exodeoxyribonuclease III OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RD02-1" }, "locus": { "chromosome": "10", "start_pos": 17387163, "end_pos": 17386681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086573.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086573.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072187.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072187.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" } ], "pmid": "" }, { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" } ], "pmid": "" }, { "name": "DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0003906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003906", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" } ], "pmid": "" }, { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" } ], "pmid": "" }, { "name": "double-stranded DNA 3'-5' DNA exonuclease activity", "id": "GO:0008311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008311", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD02", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RD02-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 161, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RD02-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RD02" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RD02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" }, { "id": "PF03372", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endonuclease/exonuclease/phosphatase", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 150, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A5G2RD02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02#function" }, { "id": "A0A5G2RD02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 13, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 13, "end_pos": 13, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RD02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02#function" }, { "id": "A0A5G2RD02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 144, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 144, "end_pos": 144, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RD02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02#function" }, { "id": "A0A5G2RD02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 146, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 146, "end_pos": 146, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RD02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02#function" }, { "id": "A0A5G2RD02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD02" }, { "id": "PIRSR604808-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604808-2" } ], "binding_site_uniprot": 42, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 42, "end_pos": 42, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RD18-1", "uniprot_ac": "A0A5G2RD18", "uniprot_id": "A0A5G2RD18_PIG", "mass": { "chemical_mass": 30346.0, "monoisotopic_mass": 30346.0 }, "refseq": {}, "gene_names": [ { "name": "EAF2", "type": "recommended", "evidence": [ { "id": "A0A5G2RD18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18" } ] } ], "protein_names": [ { "name": "ELL associated factor 2", "type": "synonym", "evidence": [ { "id": "A0A5G2RD18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EAF2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18", "locus": { "chromosome": "13", "start_pos": 138648270, "end_pos": 138681613, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011880", "url": "https://www.ensembl.org/id/ENSSSCG00000011880" } ] } } ], "crossref": [ { "id": "A0A5G2RD18", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RD18", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011880", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011880", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR019194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15970", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15970", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15970:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15970:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09816", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09816", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-112382", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112382", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-75955", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RD18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RD18-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGAGRPSRIDSRERVLKLGESFEKQPRCAFHTVRYDFKPASIDTSCEGELEVGKGEQVTITLPNIEGSTTPVTVFKGSKKPYLKECILIINHDTGECRLEKLSNNITVKKTRVEGSSKIQFRIEQQQQQMRNLAKTPNLVKHSPPEDKMSPASPMDDIERELKAEASLMDQMSSCDSSSDSKSSSSSSSEDSSSDSEAEECRSSPDPGNYISEHPTMSAMPQCRTPEIDASRNKYYDNGLMMNTLKCLSGFSRLSRCFSVSSFLVYNISHSL", "length": 273, "header": "tr|A0A5G2RD18-1|A0A5G2RD18_PIG Isoform 1 of ELL associated factor 2 OS=Sus scrofa OX=9823 GN=EAF2 PE=3 SV=1 CANONICAL=A0A5G2RD18-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RD18-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18/entry#A0A5G2RD18-1", "sequence": { "sequence": "MNGAGRPSRIDSRERVLKLGESFEKQPRCAFHTVRYDFKPASIDTSCEGELEVGKGEQVTITLPNIEGSTTPVTVFKGSKKPYLKECILIINHDTGECRLEKLSNNITVKKTRVEGSSKIQFRIEQQQQQMRNLAKTPNLVKHSPPEDKMSPASPMDDIERELKAEASLMDQMSSCDSSSDSKSSSSSSSEDSSSDSEAEECRSSPDPGNYISEHPTMSAMPQCRTPEIDASRNKYYDNGLMMNTLKCLSGFSRLSRCFSVSSFLVYNISHSL", "length": 273, "header": "tr|A0A5G2RD18-1|A0A5G2RD18_PIG Isoform 1 of ELL associated factor 2 OS=Sus scrofa OX=9823 GN=EAF2 PE=3 SV=1 CANONICAL=A0A5G2RD18-1" }, "locus": { "chromosome": "13", "start_pos": 138681504, "end_pos": 138651169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084989.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084989.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074356.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074356.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-SSC-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-SSC-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18" } ], "pmid": "" }, { "name": "super elongation complex", "id": "GO:0032783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription elongation factor activity", "id": "GO:0003711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003711", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RD18-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 273, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RD18-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RD18" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RD18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD18" }, { "id": "PF09816", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09816" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transcription elongation factor Eaf N-terminal", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 113, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 268, "end_pos": 270 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RD84-1", "uniprot_ac": "A0A5G2RD84", "uniprot_id": "A0A5G2RD84_PIG", "mass": { "chemical_mass": 34660.0, "monoisotopic_mass": 34660.0 }, "refseq": { "ac": "XP_003123313", "name": "olfactory receptor 7C1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123313" }, "gene_names": [ { "name": "LOC100521430", "type": "recommended", "evidence": [ { "id": "A0A5G2RD84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84" } ] }, { "name": "LOC100521430", "type": "synonym", "evidence": [ { "id": "XP_003123313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123313" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RD84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7C1-like", "type": "synonym", "evidence": [ { "id": "XP_003123313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123313" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100521430", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84", "locus": {} } ], "crossref": [ { "id": "A0A5G2RD84", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RD84", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521430", "url": "https://www.ncbi.nlm.nih.gov/gene/100521430", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521430", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521430", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FRNYIAM", "url": "https://omabrowser.org/oma/group/FRNYIAM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RD84", "url": "https://www.orthodb.org/?gene=A0A5G2RD84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003123313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123313", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RD84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RD84-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAGNQTWVLEFLLLGLSEDAEQQPLLFGLFLSMYLVSMLGNLLIILAVSSDSRLHTPMYFFLSHLSFSDICCSSTIVPQMLLNIQTASKAIIYSGCITQMYFSSVFLCLDNLLLTVMAFDRFVAICHPLHYRIMMNPLLCDLLALFSWSVSILFPLIPCLMALHLSFCTHTEIPHFFCELAEVLKSACSDAFRNYIAMYSLTGLLAIPPLTGIIVSYSKIIYSILKMSSLEGKYKAFSTCGSHLTVISLFYGTGLGVYLSSAFSPSSSKGAVASVMYTVVTPMLNPFIYSLRNRDLQGALRKFVSRSSFPL", "length": 312, "header": "tr|A0A5G2RD84-1|A0A5G2RD84_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100521430 PE=3 SV=1 CANONICAL=A0A5G2RD84-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RD84-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84/entry#A0A5G2RD84-1", "sequence": { "sequence": "MDAGNQTWVLEFLLLGLSEDAEQQPLLFGLFLSMYLVSMLGNLLIILAVSSDSRLHTPMYFFLSHLSFSDICCSSTIVPQMLLNIQTASKAIIYSGCITQMYFSSVFLCLDNLLLTVMAFDRFVAICHPLHYRIMMNPLLCDLLALFSWSVSILFPLIPCLMALHLSFCTHTEIPHFFCELAEVLKSACSDAFRNYIAMYSLTGLLAIPPLTGIIVSYSKIIYSILKMSSLEGKYKAFSTCGSHLTVISLFYGTGLGVYLSSAFSPSSSKGAVASVMYTVVTPMLNPFIYSLRNRDLQGALRKFVSRSSFPL", "length": 312, "header": "tr|A0A5G2RD84-1|A0A5G2RD84_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100521430 PE=3 SV=1 CANONICAL=A0A5G2RD84-1" }, "locus": { "chromosome": "2", "start_pos": 68148843, "end_pos": 68147908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070000.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070000.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072308.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072308.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521430", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521430", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD84", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RD84-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RD84-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RD84" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RD84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD84" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RDD8-1", "uniprot_ac": "A0A5G2RDD8", "uniprot_id": "A0A5G2RDD8_PIG", "mass": { "chemical_mass": 120722.0, "monoisotopic_mass": 120722.0 }, "refseq": { "ac": "XP_003129849", "name": "contactin-5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129849" }, "gene_names": [ { "name": "CNTN5", "type": "recommended", "evidence": [ { "id": "A0A5G2RDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ] }, { "name": "CNTN5", "type": "synonym", "evidence": [ { "id": "XP_003129849", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129849" } ] } ], "protein_names": [ { "name": "Contactin-5", "type": "recommended", "evidence": [ { "id": "A0A5G2RDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8/entry#names_and_taxonomy" } ] }, { "name": "contactin-5", "type": "synonym", "evidence": [ { "id": "XP_003129849", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129849" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CNTN5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8", "locus": { "chromosome": "9", "start_pos": 31469858, "end_pos": 30572372, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014975", "url": "https://www.ensembl.org/id/ENSSSCG00000014975" } ] } } ], "crossref": [ { "id": "A0A5G2RDD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RDD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014975", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014975", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04969", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04969", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05848", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05848", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519379", "url": "https://www.ncbi.nlm.nih.gov/gene/100519379", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519379", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519379", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RDD8", "url": "https://www.orthodb.org/?gene=A0A5G2RDD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003129849", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129849", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STI0", "url": "https://www.uniprot.org/uniprotkb/F1STI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STI0-1", "url": "https://www.uniprot.org/uniprotkb/F1STI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSWKLILFLSVTGCLSEYSGALPGLPTSYAALIRIKKSSSSSLYGSKTRPRYSNPSLGTLSVSSPSWRGASAQHYYSPINLYHSSDAFKQDESVDYGPVFLQEPDDIIFPTDSDEKKVALNCEARGNPVPNYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLAANTFGSVLSREAILQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKSRLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLLLQSRIEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKGQEVVIECKPQGSPKPTISWKKGDKAVRENKRIAILPDGSLRILNASKSDEGKYVCQGENVFGSAEIIASISVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFQKEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITDSTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQGFEIGYWKDMEQEDAAETVKTRGNESSIILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPNNLRWEQQGSQLSLGWEPVRPLANESEVMGYKVFYRQEGHSNSQVIETQKPQAVVPLPDAGVYIIEVRAYSEGGDGTASSQIRVSSYSGGKITSAQSTLHTLSTSSSSVTLLLALVIPSTSW", "length": 1101, "header": "tr|A0A5G2RDD8-1|A0A5G2RDD8_PIG Isoform 1 of Contactin-5 OS=Sus scrofa OX=9823 GN=CNTN5 PE=3 SV=1 CANONICAL=A0A5G2RDD8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RDD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8/entry#A0A5G2RDD8-1", "sequence": { "sequence": "MASSWKLILFLSVTGCLSEYSGALPGLPTSYAALIRIKKSSSSSLYGSKTRPRYSNPSLGTLSVSSPSWRGASAQHYYSPINLYHSSDAFKQDESVDYGPVFLQEPDDIIFPTDSDEKKVALNCEARGNPVPNYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLAANTFGSVLSREAILQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKSRLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLLLQSRIEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKGQEVVIECKPQGSPKPTISWKKGDKAVRENKRIAILPDGSLRILNASKSDEGKYVCQGENVFGSAEIIASISVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFQKEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITDSTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQGFEIGYWKDMEQEDAAETVKTRGNESSIILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPNNLRWEQQGSQLSLGWEPVRPLANESEVMGYKVFYRQEGHSNSQVIETQKPQAVVPLPDAGVYIIEVRAYSEGGDGTASSQIRVSSYSGGKITSAQSTLHTLSTSSSSVTLLLALVIPSTSW", "length": 1101, "header": "tr|A0A5G2RDD8-1|A0A5G2RDD8_PIG Isoform 1 of Contactin-5 OS=Sus scrofa OX=9823 GN=CNTN5 PE=3 SV=1 CANONICAL=A0A5G2RDD8-1" }, "locus": { "chromosome": "9", "start_pos": 31467214, "end_pos": 30792539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087083.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087083.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072383.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072383.1" } ] } }, { "isoform_ac": "F1STI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8/entry#F1STI0-1", "sequence": { "sequence": "MASSWKLILFLSVTGCLSESVDYGPVFLQEPDDIIFPTDSDEKKVALNCEARGNPVPNYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLAANTFGSVLSREAILQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKSRLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLLLQSRIEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKGQEVVIECKPQGSPKPTISWKKGDKAVRENKRIAILPDGSLRILNASKSDEGKYVCQGENVFGSAEIIASISVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFQKEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITDSTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQGFEIGYWKDMEQEDAAETVKTRGNESSIILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPNNLRWEQQGSQLSLGWEPVRPLANESEVMGYKVFYRQEGHSNSQVIETQKPQAVVPLPDAGVYIIEVRAYSEGGDGTASSQIRVSSYSGGKITSAQSTLHTLSTSSSSVTLLLALVIPSTSW", "length": 1026, "header": "tr|F1STI0-1|A0A5G2RDD8_PIG Computationally mapped isoform of Contactin-5 OS=Sus scrofa OX=9823 GN=CNTN5 PE=3 SV=3 CANONICAL=A0A5G2RDD8-1" }, "locus": { "chromosome": "9", "start_pos": 31467214, "end_pos": 30792539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016337.3", "url": "https://www.ensembl.org/id/ENSSSCT00000016337.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015898.3", "url": "https://www.ensembl.org/id/ENSSSCP00000015898.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 762, "start_aa": "Thr", "end_pos": 762, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr762", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1STI0", "url": "https://www.uniprot.org/uniprotkb/F1STI0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519379", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519379", "resource": "KEGG Pathway" }, { "id": "R-SSC-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "presynapse assembly", "id": "GO:0099054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099054", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDD8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1003, "end_pos": 1005, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" }, { "start_pos": 698, "end_pos": 700, "annotation": "n_glycosylation_sequon" }, { "start_pos": 780, "end_pos": 782, "annotation": "n_glycosylation_sequon" }, { "start_pos": 817, "end_pos": 819, "annotation": "n_glycosylation_sequon" }, { "start_pos": 932, "end_pos": 934, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RDD8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1101, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RDD8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RDD8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 674, "end_pos": 772, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDD8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 106, "end_pos": 191, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 762 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1003, "end_pos": 1005 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 398, "end_pos": 400 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 541, "end_pos": 543 }, { "start_pos": 698, "end_pos": 700 }, { "start_pos": 780, "end_pos": 782 }, { "start_pos": 817, "end_pos": 819 }, { "start_pos": 932, "end_pos": 934 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RDG3-1", "uniprot_ac": "A0A5G2RDG3", "uniprot_id": "A0A5G2RDG3_PIG", "mass": { "chemical_mass": 83483.0, "monoisotopic_mass": 83483.0 }, "refseq": {}, "gene_names": [ { "name": "NAALADL1", "type": "recommended", "evidence": [ { "id": "A0A5G2RDG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" } ] } ], "protein_names": [ { "name": "Aminopeptidase NAALADL1", "type": "recommended", "evidence": [ { "id": "A0A5G2RDG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3/entry#names_and_taxonomy" } ] }, { "name": "N-acetylated-alpha-linked acidic dipeptidase-like protein", "type": "synonym", "evidence": [ { "id": "A0A5G2RDG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Aminopeptidase with broad substrate specificity. Has lower activity with substrates that have Asp or Glu in the P2' position, or Pro in the P3' position. Lacks activity with substrates that have both Pro in the P3' position and Asp or Glu in the P2' position. Lacks carboxypeptidase activity. Lacks dipeptidyl-peptidase IV type activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3#function" }, { "database": "UniProtKB", "id": "ARBA00059290", "url": "https://www.uniprot.org/uniprotkb/ARBA00059290#function" }, { "database": "UniProtKB", "id": "F1RQT1", "url": "https://www.uniprot.org/uniprotkb/F1RQT1#function" }, { "database": "UniProtKB", "id": "A0A8W4FI48", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI48#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NAALADL1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3", "locus": { "chromosome": "2", "start_pos": 7138415, "end_pos": 7127624, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013010", "url": "https://www.ensembl.org/id/ENSSSCG00000013010" } ] } } ], "crossref": [ { "id": "A0A5G2RDG3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RDG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013010", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013010", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02121", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02121", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08022", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08022", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10404:SF50", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10404:SF50", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI48", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQT1", "url": "https://www.uniprot.org/uniprotkb/F1RQT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQT1-1", "url": "https://www.uniprot.org/uniprotkb/F1RQT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPWVKVLGGVVGAAALLGLGIILGHFAIPKGANQPASQELDLDPEILETVMGQLDANRIRENLRELSKEPHVASSPRDEALVQLLLQRWQDPDSGLDSAGTSEYEVLLSFPSQEQPNHVDVVGPSGDILFTCRRSEENLTKDQEAPDVLSPYAAYAPPGTPQGLLVYANQGSEEDFLYLYNEGINLQDTIALTRYGGVGRGAKAVNAAKYGVAGVLVYTDPGDINDGKSLPNETYPHSWGLPPSGVERGSYFEYFGDPLTPYLPANPSSFRLDSANASGFPPIPTQPIGFEDAKVLLCNLQGNSAPEDWQGALGCEYNLGPGFRPDGNFSADRTASAVAVPSDGNTLPHALPLLPAPTSLPATSQVNVSVHNRLVLRNSSNVLGIIRGAVEPDRYVIYGNHRDSWVHGAVDPSSGTSVLLEISRVLGTLLKKGTWRPRRSIVFASWGAEEFGLIGSTEFTEEFFSKLQERTVAYINVDISVFANATLRAQGTPPVQSVIFSAAKQIPAPGRSSLSIYDNWIQYFNRSSPVYGLVPSLGTLGAGSDYAPFIHFLGISSMDLAYTYDRSKTSARIYPTYHTAFDTFDYVDKFVDPGFSSHQAVARTAGSVLLRLSDSLFLPLNVSDYSETLHSFLQAAQQNLGTLLEQQSISLGPLVTAVEKFDEAATALGQHISALQKGTPDPLQVRMLNDQLMLLERTFLNSRAFPDERYYSHVLWAPRTGSVATFPGLSNACSRAMNTTSGSAAWAEVQRQLSILVAALEGAAATLRPVAEL", "length": 773, "header": "tr|A0A5G2RDG3-1|A0A5G2RDG3_PIG Isoform 1 of Aminopeptidase NAALADL1 OS=Sus scrofa OX=9823 GN=NAALADL1 PE=1 SV=1 CANONICAL=A0A5G2RDG3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RDG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3/entry#A0A5G2RDG3-1", "sequence": { "sequence": "MPWVKVLGGVVGAAALLGLGIILGHFAIPKGANQPASQELDLDPEILETVMGQLDANRIRENLRELSKEPHVASSPRDEALVQLLLQRWQDPDSGLDSAGTSEYEVLLSFPSQEQPNHVDVVGPSGDILFTCRRSEENLTKDQEAPDVLSPYAAYAPPGTPQGLLVYANQGSEEDFLYLYNEGINLQDTIALTRYGGVGRGAKAVNAAKYGVAGVLVYTDPGDINDGKSLPNETYPHSWGLPPSGVERGSYFEYFGDPLTPYLPANPSSFRLDSANASGFPPIPTQPIGFEDAKVLLCNLQGNSAPEDWQGALGCEYNLGPGFRPDGNFSADRTASAVAVPSDGNTLPHALPLLPAPTSLPATSQVNVSVHNRLVLRNSSNVLGIIRGAVEPDRYVIYGNHRDSWVHGAVDPSSGTSVLLEISRVLGTLLKKGTWRPRRSIVFASWGAEEFGLIGSTEFTEEFFSKLQERTVAYINVDISVFANATLRAQGTPPVQSVIFSAAKQIPAPGRSSLSIYDNWIQYFNRSSPVYGLVPSLGTLGAGSDYAPFIHFLGISSMDLAYTYDRSKTSARIYPTYHTAFDTFDYVDKFVDPGFSSHQAVARTAGSVLLRLSDSLFLPLNVSDYSETLHSFLQAAQQNLGTLLEQQSISLGPLVTAVEKFDEAATALGQHISALQKGTPDPLQVRMLNDQLMLLERTFLNSRAFPDERYYSHVLWAPRTGSVATFPGLSNACSRAMNTTSGSAAWAEVQRQLSILVAALEGAAATLRPVAEL", "length": 773, "header": "tr|A0A5G2RDG3-1|A0A5G2RDG3_PIG Isoform 1 of Aminopeptidase NAALADL1 OS=Sus scrofa OX=9823 GN=NAALADL1 PE=1 SV=1 CANONICAL=A0A5G2RDG3-1" }, "locus": { "chromosome": "2", "start_pos": 7137931, "end_pos": 7127654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081922.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081922.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074537.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074537.1" } ] } }, { "isoform_ac": "A0A8W4FI48-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3/entry#A0A8W4FI48-1", "sequence": { "sequence": "MSGLSQQRRGAGTWRPRRSIVFASWGAEEFGLIGSTEFTEEFFSKLQERTVAYINVDISVFANATLRAQGTPPVQSVIFSAAKQIPAPGRSSLSIYDNWIQYFNRSSPVYGLVPSLGTLGAGSDYAPFIHFLGISSMDLAYTYDRSKTSARIYPTYHTAFDTFDYVDKFVDPGFSSHQAVARTAGSVLLRLSDSLFLPLNVSDYSETLHSFLQAAQQNLGTLLEQQSISLGPLVTAVEKFDEAATALGQHISALQKGTPDPLQVRMLNDQLMLLERTFLNSRAFPDERYYSHVLWAPRTGSVATFPGLSNACSRAMNTTSGSAAWAEVQRQLSILVAALEGAAATLRPVAEL", "length": 352, "header": "tr|A0A8W4FI48-1|A0A5G2RDG3_PIG Computationally mapped isoform of Aminopeptidase NAALADL1 OS=Sus scrofa OX=9823 GN=NAALADL1 PE=1 SV=1 CANONICAL=A0A5G2RDG3-1" }, "locus": { "chromosome": "2", "start_pos": 7137931, "end_pos": 7134889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101446.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101446.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079121.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079121.1" } ] } }, { "isoform_ac": "F1RQT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3/entry#F1RQT1-1", "sequence": { "sequence": "MPWVKVLGGVVGAAALLGLGIILGHFAIPKGANQPASQELDLDPEILETVMGQLDANRIRENLRELSKEPHVASSPRDEALVQLLLQRWQDPDSGLDSAGTSEYEVLLSFPSQEQPNHVDVVGPSGDILFTCRRSEENLTKDQEAPDVLSPYAAYAPPGTPQGLLVYANQGSEEDFLYLYNEGINLQDTIALTRYGGVGRGAKAVNAAKYGVAGVLVYTDPGDINDGKSLPNETYPHSWGLPPSGVERGSYFEYFGDPLTPYLPANPSSFRLDSANASGFPPIPTQPIGFEDAKVLLCNLQGNSAPEDWQGALGCEYNLGPGFRPDGNFSADSQVNVSVHNRLVLRNSSNVLGIIRGAVEPDRYVIYGNHRDSWVHGAVDPSSGTSVLLEISRVLGTLLKKGTWRPRRSIVFASWGAEEFGLIGSTEFTEEFFSKLQERTVAYINVDISVFANATLRAQGTPPVQSVIFSAAKQIPAPGRSSLSIYDNWIQYFNRSSPVYGLVPSLGTLGAGSDYAPFIHFLGISSMDLAYTYDRLLPLPILSLPTLALFPQSKTSARIYPTYHTAFDTFDYVDKFVDPGFSSHQAVARTAGSVLLRLSDSLFLPLNVSDYSETLHSFLQAAQQNLGTLLEQQSISLGPLVTAVEKFDEAATALGQHISALQKGTPDPLQVRMLNDQLMLLERTFLNSRAFPDERYYSHVLWAPRTGSVATFPGLSNACSRAMNTTSGSAAWAEVQRQLSILVAALEGAAATLRPVAEL", "length": 759, "header": "tr|F1RQT1-1|A0A5G2RDG3_PIG Computationally mapped isoform of Aminopeptidase NAALADL1 OS=Sus scrofa OX=9823 GN=NAALADL1 PE=1 SV=2 CANONICAL=A0A5G2RDG3-1" }, "locus": { "chromosome": "2", "start_pos": 7137931, "end_pos": 7127654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014221.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014221.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013835.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013835.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FI48", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI48" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" } ], "pmid": "" }, { "name": "peptide catabolic process", "id": "GO:0043171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043171", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" } ], "pmid": "" }, { "name": "carboxypeptidase activity", "id": "GO:0004180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004180", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 525, "end_pos": 527, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RDG3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 773, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RDG3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RDG3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RDG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" }, { "id": "PF02225", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PA", "eco_id": "ECO_0000259", "start_pos": 164, "end_pos": 249, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RDG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" }, { "id": "PF04389", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M28", "eco_id": "ECO_0000259", "start_pos": 381, "end_pos": 589, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RDG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDG3" }, { "id": "PF04253", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04253" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transferrin receptor-like dimerisation", "eco_id": "ECO_0000259", "start_pos": 649, "end_pos": 768, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 367, "end_pos": 369 }, { "start_pos": 378, "end_pos": 380 }, { "start_pos": 484, "end_pos": 486 }, { "start_pos": 525, "end_pos": 527 }, { "start_pos": 621, "end_pos": 623 }, { "start_pos": 738, "end_pos": 740 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RDL1-1", "uniprot_ac": "A0A5G2RDL1", "uniprot_id": "A0A5G2RDL1_PIG", "mass": { "chemical_mass": 35410.0, "monoisotopic_mass": 35410.0 }, "refseq": { "ac": "XP_020941149", "name": "olfactory receptor 2L5-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941149" }, "gene_names": [ { "name": "LOC110259749", "type": "recommended", "evidence": [ { "id": "A0A5G2RDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1" } ] }, { "name": "LOC110259749", "type": "synonym", "evidence": [ { "id": "XP_020941149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941149" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2L5-like", "type": "synonym", "evidence": [ { "id": "XP_020941149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941149" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDL1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDL1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259749", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1", "locus": {} } ], "crossref": [ { "id": "A0A5G2RDL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RDL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000046264", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000046264", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110259749", "url": "https://www.ncbi.nlm.nih.gov/gene/110259749", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110259749", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259749", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CRSRNIN", "url": "https://omabrowser.org/oma/group/CRSRNIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RDL1", "url": "https://www.orthodb.org/?gene=A0A5G2RDL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020941149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941149", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RDL1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESYNQTSTDFILLGLFPPSSIGLFLFILIVLIFLVALFGNLSMILLISLDNHLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFGDKSISLLGCGVQSFFFLTLAGAEGLLLASMAYDRYVAICFPLHYSIRISRRVCVLMIMGSWMMGSINSCAHTTCILYIPYCQSRAINHFFCDVTVMLTMACIDTRIYEYTVFVSTTIFLLLPFIGIAFSYGCVLLAVYQMHSADGKKKAYSTCSTHLTVVTLYYSPFVYTYLRPRFLRTPIEDKALAVLYTILTPMLNPIIYSLRNKEVIGALKRVIERIRSLKM", "length": 312, "header": "tr|A0A5G2RDL1-1|A0A5G2RDL1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259749 PE=3 SV=1 CANONICAL=A0A5G2RDL1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RDL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1/entry#A0A5G2RDL1-1", "sequence": { "sequence": "MESYNQTSTDFILLGLFPPSSIGLFLFILIVLIFLVALFGNLSMILLISLDNHLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFGDKSISLLGCGVQSFFFLTLAGAEGLLLASMAYDRYVAICFPLHYSIRISRRVCVLMIMGSWMMGSINSCAHTTCILYIPYCQSRAINHFFCDVTVMLTMACIDTRIYEYTVFVSTTIFLLLPFIGIAFSYGCVLLAVYQMHSADGKKKAYSTCSTHLTVVTLYYSPFVYTYLRPRFLRTPIEDKALAVLYTILTPMLNPIIYSLRNKEVIGALKRVIERIRSLKM", "length": 312, "header": "tr|A0A5G2RDL1-1|A0A5G2RDL1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259749 PE=3 SV=1 CANONICAL=A0A5G2RDL1-1" }, "locus": { "chromosome": "2", "start_pos": 55060117, "end_pos": 55059182, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074088.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074088.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068809.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068809.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDL1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110259749", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259749", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDL1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDL1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDL1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDL1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RDL1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RDL1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RDL1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDL1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RDM3-1", "uniprot_ac": "A0A5G2RDM3", "uniprot_id": "A0A5G2RDM3_PIG", "mass": { "chemical_mass": 48236.0, "monoisotopic_mass": 48236.0 }, "refseq": {}, "gene_names": [ { "name": "PCYOX1L", "type": "recommended", "evidence": [ { "id": "A0A5G2RDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3" } ] } ], "protein_names": [ { "name": "prenylcysteine oxidase", "type": "recommended", "evidence": [ { "id": "A0A5G2RDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3/entry#names_and_taxonomy" } ] }, { "name": "1.8.3.5", "type": "synonym", "evidence": [ { "id": "A0A5G2RDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PCYOX1L", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3", "locus": { "chromosome": "2", "start_pos": 150537517, "end_pos": 150526174, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014433", "url": "https://www.ensembl.org/id/ENSSSCG00000014433" } ] } } ], "crossref": [ { "id": "A0A5G2RDM3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RDM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014433", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014433", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR010795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15944", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15944", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15944:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15944:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07156", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07156", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13450", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13450", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "30231", "url": "https://www.rhea-db.org/rhea/30231", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70407", "url": "https://www.rhea-db.org/rhea/70407", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RDM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RL93", "url": "https://www.uniprot.org/uniprotkb/F1RL93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RL93-1", "url": "https://www.uniprot.org/uniprotkb/F1RL93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARAARLLPALAALLAAAATGDARPSKIAVVGAGVGGSAVAHFLQQHFGPRVQIDVFEKGTVGGRLATISVNKQHYESGAASLHSLSLHMQDFVKQLGLRHRREVGGRSAIFNGESLVLEETDWYLLNLFRLWWHYGISFLRLQLWVEEVMEKFMRIYKYQAHGYAFSGVEELLYSLGEAAFINMSRRSVAESLLRVGVSQRFIDDVVSAVLRASYGQSAAMPAFAGAMSLAGAQGSLWSVEGGNKLVCSGLLKLTKANVIHATVTSVTLQQTDGKPLYQVWYENEAGVGSDYYDIVVIATPLHPDSGSSITFGASTRPSPSPKALSSPPWSPWSTATSTPPTSASPTPSSSPSPPSSPPTSPASSWPWTTSAPSTSRPASGAGSRRRPPCGGSGPHSPSSGPSSRPSSAPTTRSRRPSGRPTPSTAPTARSRASCCTTSSSTSTPWSGRPAPWR", "length": 455, "header": "tr|A0A5G2RDM3-1|A0A5G2RDM3_PIG Isoform 1 of prenylcysteine oxidase OS=Sus scrofa OX=9823 GN=PCYOX1L PE=1 SV=1 CANONICAL=A0A5G2RDM3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RDM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3/entry#A0A5G2RDM3-1", "sequence": { "sequence": "MARAARLLPALAALLAAAATGDARPSKIAVVGAGVGGSAVAHFLQQHFGPRVQIDVFEKGTVGGRLATISVNKQHYESGAASLHSLSLHMQDFVKQLGLRHRREVGGRSAIFNGESLVLEETDWYLLNLFRLWWHYGISFLRLQLWVEEVMEKFMRIYKYQAHGYAFSGVEELLYSLGEAAFINMSRRSVAESLLRVGVSQRFIDDVVSAVLRASYGQSAAMPAFAGAMSLAGAQGSLWSVEGGNKLVCSGLLKLTKANVIHATVTSVTLQQTDGKPLYQVWYENEAGVGSDYYDIVVIATPLHPDSGSSITFGASTRPSPSPKALSSPPWSPWSTATSTPPTSASPTPSSSPSPPSSPPTSPASSWPWTTSAPSTSRPASGAGSRRRPPCGGSGPHSPSSGPSSRPSSAPTTRSRRPSGRPTPSTAPTARSRASCCTTSSSTSTPWSGRPAPWR", "length": 455, "header": "tr|A0A5G2RDM3-1|A0A5G2RDM3_PIG Isoform 1 of prenylcysteine oxidase OS=Sus scrofa OX=9823 GN=PCYOX1L PE=1 SV=1 CANONICAL=A0A5G2RDM3-1" }, "locus": { "chromosome": "2", "start_pos": 150537129, "end_pos": 150526229, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077752.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077752.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072510.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072510.1" } ] } }, { "isoform_ac": "F1RL93-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3/entry#F1RL93-1", "sequence": { "sequence": "GGQPSLGAVVGAGVGGSAVAHFLQQHFGPRVQIDVFEKGTVGGRLATISVNKQHYESGAASLHSLSLHMQDFVKQLGLRHRREVGGRSAIFNGESLVLEETDWYLLNLFRLWWHYGISFLRLQLWVEEVMEKFMRIYKYQAHGYAFSGVEELLYSLGEAAFINMSRRSVAESLLRVGVSQRFIDDVVSAVLRASYGQSAAMPAFAGAMSLAGAQGSLWSVEGGNKLVCSGLLKLTKANVIHATVTSVTLQQTDGKPLYQVWYENEAGVGSDYYDIVVIATPLHPDSGSSITFGASTRPSPSPKALSSPPWSPWSTATSTPPTSASPTPSSSPSPPSSPPTSPASSWPWTTSAPSTSRPASGAGSRRRPPCGGSGPHSPSSGPSSRPSSAPTTRSRRPSGRPTPSTAPTARSRASCCTTSSSTSTPWSGRPAPWR", "length": 434, "header": "tr|F1RL93-1|A0A5G2RDM3_PIG Computationally mapped isoform of prenylcysteine oxidase OS=Sus scrofa OX=9823 GN=PCYOX1L PE=1 SV=4 CANONICAL=A0A5G2RDM3-1" }, "locus": { "chromosome": "2", "start_pos": 150537129, "end_pos": 150529286, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015778.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015778.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015362.5", "url": "https://www.ensembl.org/id/ENSSSCP00000015362.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 348, "start_aa": "Thr", "end_pos": 348, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr348", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 423, "start_aa": "Thr", "end_pos": 423, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr423", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RL93", "url": "https://www.uniprot.org/uniprotkb/F1RL93" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "prenylcysteine oxidase activity", "id": "GO:0001735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001735", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "neutrophil-mediated killing of bacterium", "id": "GO:0070944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070944", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3" } ], "pmid": "" }, { "name": "prenylcysteine catabolic process", "id": "GO:0030328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030328", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3" } ], "pmid": "" }, { "name": "prenylated protein catabolic process", "id": "GO:0030327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030327", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "30231", "name": "", "equation": "S-(2E,6E)-farnesyl-L-cysteine + O2 + H2O = (2E,6E)-farnesal + L-cysteine + H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "30231", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30231" } ] }, { "id": "70407", "name": "", "equation": "[(2E,6E,10E)-geranylgeranyl]-L-cysteine + O2 + H2O = (2E,6E,10E)-geranylgeranial + L-cysteine + H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70407", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70407" } ] }, { "id": "R-SSC-481007", "name": "Exocytosis of platelet alpha granule contents", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-481007", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-481007" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RDM3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 455, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RDM3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RDM3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM3" }, { "id": "PF07156", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07156" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Prenylcysteine lyase", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 318, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 348, 423 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RDQ4-1", "uniprot_ac": "A0A5G2RDQ4", "uniprot_id": "A0A5G2RDQ4_PIG", "mass": { "chemical_mass": 34678.0, "monoisotopic_mass": 34678.0 }, "refseq": { "ac": "XP_020917936", "name": "olfactory receptor 502", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020917936" }, "gene_names": [ { "name": "LOC110255353", "type": "synonym", "evidence": [ { "id": "XP_020917936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020917936" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RDQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 502", "type": "synonym", "evidence": [ { "id": "XP_020917936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020917936" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4", "locus": {} } ], "crossref": [ { "id": "A0A5G2RDQ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RDQ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000047231", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000047231", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15416", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15416", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110255353", "url": "https://www.ncbi.nlm.nih.gov/gene/110255353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110255353", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHFTEGR", "url": "https://omabrowser.org/oma/group/MHFTEGR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RDQ4", "url": "https://www.orthodb.org/?gene=A0A5G2RDQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020917936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020917936", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSLGEGNHTAVTEFILLGLTNDPTLQTVLFVVILCIYLVTICGNLSTIILIRLSPQLHHPMYFFLSHLALVDMGFSSSVTPNMLVNFLVERNTISYPGCAIQLGSAVFFGTVECFLLAAMAYDRFVAICNPLLYSTKMSMQVCVQLLLVSYMGGFLNAFAFTISFYSLLFCGPNRVNHFFCDFAPLLELSCSDITVPAIVPSCIAGSIIVVTVVVIATSYIYILITVLKMPSTEGRHKAFSTCTSHLTAVTLFYGTITFIYVMPKSSYSTDQNKVVSVFYMVVIPMLNPLIYSLRNKEIKGALKRQLGRKIFS", "length": 314, "header": "tr|A0A5G2RDQ4-1|A0A5G2RDQ4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RDQ4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RDQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4/entry#A0A5G2RDQ4-1", "sequence": { "sequence": "MGSLGEGNHTAVTEFILLGLTNDPTLQTVLFVVILCIYLVTICGNLSTIILIRLSPQLHHPMYFFLSHLALVDMGFSSSVTPNMLVNFLVERNTISYPGCAIQLGSAVFFGTVECFLLAAMAYDRFVAICNPLLYSTKMSMQVCVQLLLVSYMGGFLNAFAFTISFYSLLFCGPNRVNHFFCDFAPLLELSCSDITVPAIVPSCIAGSIIVVTVVVIATSYIYILITVLKMPSTEGRHKAFSTCTSHLTAVTLFYGTITFIYVMPKSSYSTDQNKVVSVFYMVVIPMLNPLIYSLRNKEIKGALKRQLGRKIFS", "length": 314, "header": "tr|A0A5G2RDQ4-1|A0A5G2RDQ4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RDQ4-1" }, "locus": { "chromosome": "9", "start_pos": 1737563, "end_pos": 1736622, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071909.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071909.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072570.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072570.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110255353", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255353", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LUG6-1", "protein_name": "Olfactory receptor", "gene_name": "OR5P86", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSLWQRNGTTMTGFILLGLTNDPVLRIILFMIILCIYLVTICGNLSTIILIRISSQLHHPMYFFLSHLAIADVGYSSSVTPNMLVNFLVETNTISYPGCAIQLGSAVFFGSTECILLAAMAYDRFIAICSPLLYSTKMSTQICVQLLILAYIGGFFNASSFTISFYFLHFCGPNRVNHFFCDFAPLVELSCSDISIPAAVPSFMAGSIVVITVTVIAVSYIYILITILKMHSTEGSHKAFSTCTSHLTAVTLFYGTITFIYVMPKSSYSTDQNKVVSVFYVVVIPMLNPLIYSLRNNEIKGALKRACQKNTFLVKSVIS", "length": 320 }, "evidence": [ { "id": "A0A5G2RDQ4", "url": "https://omabrowser.org/oma/group/A0A5G2RDQ4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VG09-1", "protein_name": "Olfactory receptor 5P76", "gene_name": "Or5p76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLEDGNHTAVTGFILLGLTDDPVLRVVLFVIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASADIGYSSSVTPNMLVNFLVERNTISYLGCGIQLGSAVFFGTVECFLLAAMAYDRFIAICSPLLYSNKMSTQVCVQLLVGSYIGGFLNASSFTLSFFSLVFCGPNRVNHFFCDFAPLVKLSCSDVSVPAVVPSFTAGSIIIVTIFVIAVSYIYILITILKMRSTEGRQKAFSTCTSHLTAVTLFYGTITFIYVMPKSSYSTDQNKVVSVFYMVVVPMLNPLIYSLRNKEIKGALKRQLAKNTFS", "length": 314 }, "evidence": [ { "id": "A0A5G2RDQ4", "url": "https://omabrowser.org/oma/group/A0A5G2RDQ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RDQ4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RDQ4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RDQ4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RDQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDQ4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 293, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RDX8-1", "uniprot_ac": "A0A5G2RDX8", "uniprot_id": "A0A5G2RDX8_PIG", "mass": { "chemical_mass": 13894.0, "monoisotopic_mass": 13894.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Large ribosomal subunit protein mL51", "type": "recommended", "evidence": [ { "id": "A0A5G2RDX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX8/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L51, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A5G2RDX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX8", "locus": {} } ], "crossref": [ { "id": "A0A5G2RDX8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RDX8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045051", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045051", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR019373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13409:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13409:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RDX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVCIIGILGNLEKHPKELIKGPIWLRGWKGNELQHCIRKKRRAGNRMFTDDLHNLNKGISYLYKHFNQRGKYGRRESWKRHINHPREGESDLYALSNKMGLKGKKKKKKKDDDRSKK", "length": 117, "header": "tr|A0A5G2RDX8-1|A0A5G2RDX8_PIG Isoform 1 of Large ribosomal subunit protein mL51 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RDX8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RDX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX8/entry#A0A5G2RDX8-1", "sequence": { "sequence": "MVCIIGILGNLEKHPKELIKGPIWLRGWKGNELQHCIRKKRRAGNRMFTDDLHNLNKGISYLYKHFNQRGKYGRRESWKRHINHPREGESDLYALSNKMGLKGKKKKKKKDDDRSKK", "length": 117, "header": "tr|A0A5G2RDX8-1|A0A5G2RDX8_PIG Isoform 1 of Large ribosomal subunit protein mL51 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RDX8-1" }, "locus": { "chromosome": "10", "start_pos": 47182444, "end_pos": 47182094, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088321.1", "url": "https://www.ensembl.org/id/ENSSSCT00000088321.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072715.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072715.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDX8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDX8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RDX8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 117, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RDX8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RDX8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RE13-1", "uniprot_ac": "A0A5G2RE13", "uniprot_id": "A0A5G2RE13_PIG", "mass": { "chemical_mass": 57870.0, "monoisotopic_mass": 57870.0 }, "refseq": {}, "gene_names": [ { "name": "STAM", "type": "recommended", "evidence": [ { "id": "A0A5G2RE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ] } ], "protein_names": [ { "name": "Signal transducing adaptor molecule", "type": "synonym", "evidence": [ { "id": "A0A5G2RE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as a sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13#function" }, { "database": "UniProtKB", "id": "ARBA00043869", "url": "https://www.uniprot.org/uniprotkb/ARBA00043869#function" }, { "database": "UniProtKB", "id": "F1RWA6", "url": "https://www.uniprot.org/uniprotkb/F1RWA6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "STAM", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13", "locus": { "chromosome": "10", "start_pos": 44016056, "end_pos": 43947011, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011036", "url": "https://www.ensembl.org/id/ENSSSCG00000011036" } ] } } ], "crossref": [ { "id": "A0A5G2RE13", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RE13", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011036", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011036", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11964", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11964", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17000", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17000", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21389", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21389", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047528", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047528", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050670", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050670", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45929", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45929", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45929:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45929:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02809", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02809", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-182971", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-182971", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5689901", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689901", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6807004", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807004", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013420", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013420", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-917729", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917729", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RE13-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWA6", "url": "https://www.uniprot.org/uniprotkb/F1RWA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWA6-1", "url": "https://www.uniprot.org/uniprotkb/F1RWA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLFATNPFDQDVEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSVMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNHQHEGRKVRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGMGLFPSNFVTADLTAEPEMIKTEKKTVQFSDDVQVETIEPEPEQAYIDEDKMDQLLQMLQSTDPSDDQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNGKVMEALSLYTKLMNEDPMYSMYAKLQNQQYYIQSSGVSGSQVYPGPPQSGAYLVAGTAQMSHLQTYSLPPEQLSSLSPGGVPPPASPALPSQPTPASYTKSFTVSGLKFKSLIHFKFIFVDGVSQGPFSFLCMSRFSHLYLLRRPSFSCCVYLVPWSNP", "length": 521, "header": "tr|A0A5G2RE13-1|A0A5G2RE13_PIG Isoform 1 of Signal transducing adaptor molecule OS=Sus scrofa OX=9823 GN=STAM PE=1 SV=1 CANONICAL=A0A5G2RE13-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RE13-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13/entry#A0A5G2RE13-1", "sequence": { "sequence": "MPLFATNPFDQDVEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSVMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNHQHEGRKVRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGMGLFPSNFVTADLTAEPEMIKTEKKTVQFSDDVQVETIEPEPEQAYIDEDKMDQLLQMLQSTDPSDDQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNGKVMEALSLYTKLMNEDPMYSMYAKLQNQQYYIQSSGVSGSQVYPGPPQSGAYLVAGTAQMSHLQTYSLPPEQLSSLSPGGVPPPASPALPSQPTPASYTKSFTVSGLKFKSLIHFKFIFVDGVSQGPFSFLCMSRFSHLYLLRRPSFSCCVYLVPWSNP", "length": 521, "header": "tr|A0A5G2RE13-1|A0A5G2RE13_PIG Isoform 1 of Signal transducing adaptor molecule OS=Sus scrofa OX=9823 GN=STAM PE=1 SV=1 CANONICAL=A0A5G2RE13-1" }, "locus": { "chromosome": "10", "start_pos": 44012168, "end_pos": 43947211, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076904.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076904.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069037.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069037.1" } ] } }, { "isoform_ac": "F1RWA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13/entry#F1RWA6-1", "sequence": { "sequence": "MPLFATNPFDQDVEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSVMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNHQHEGRKVRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGMGLFPSNFVTADLTAEPEMIKTEKKTVQFSDDVQVETIEPEPEQAYIDEDKMDQLLQMLQSTDPSDDQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNGKVMEALSLYTKLMNEDPMYSMYAKLQNQQYYIQSSGVSGSQHNGQLCSGKYVSHAGFGVQSSCCRRGCCHHHDVTIYQNAGTSLSQVPNYNLTSALPQPSGGQQPPPPSSRILRRPCYRTGDSSLWQIPAPCR", "length": 495, "header": "tr|F1RWA6-1|A0A5G2RE13_PIG Computationally mapped isoform of Signal transducing adaptor molecule OS=Sus scrofa OX=9823 GN=STAM PE=1 SV=3 CANONICAL=A0A5G2RE13-1" }, "locus": { "chromosome": "10", "start_pos": 44015010, "end_pos": 43947211, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012079.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012079.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011771.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011771.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 456, "start_aa": "Thr", "end_pos": 456, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr456", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWA6", "url": "https://www.uniprot.org/uniprotkb/F1RWA6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-182971", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-182971", "resource": "Reactome", "description": "EGFR downregulation" }, { "id": "R-SSC-5689901", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689901", "resource": "Reactome", "description": "Metalloprotease DUBs" }, { "id": "R-SSC-6807004", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807004", "resource": "Reactome", "description": "Negative regulation of MET activity" }, { "id": "R-SSC-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-SSC-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" }, { "id": "R-SSC-9013420", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013420", "resource": "Reactome", "description": "RHOU GTPase cycle" }, { "id": "R-SSC-917729", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917729", "resource": "Reactome", "description": "Endosomal Sorting Complex Required For Transport (ESCRT)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "multivesicular body assembly", "id": "GO:0036258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036258", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ], "pmid": "" }, { "name": "protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043328", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ], "pmid": "" }, { "name": "positive regulation of exosomal secretion", "id": "GO:1903543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903543", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ], "pmid": "" }, { "name": "regulation of extracellular exosome assembly", "id": "GO:1903551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903551", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ESCRT-0 complex", "id": "GO:0033565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033565", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ], "pmid": "" }, { "name": "ubiquitin-like protein ligase binding", "id": "GO:0044389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044389", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RE13-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 521, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RE13-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RE13" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 210, "end_pos": 269, "start_aa": "His", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE13" }, { "id": "PS50179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VHS", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 143, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 456 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RE51-1", "uniprot_ac": "A0A5G2RE51", "uniprot_id": "A0A5G2RE51_PIG", "mass": { "chemical_mass": 44816.0, "monoisotopic_mass": 44816.0 }, "refseq": { "ac": "XP_020936544", "name": "heat shock transcription factor, Y-linked-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936544" }, "gene_names": [ { "name": "LOC110257887", "type": "synonym", "evidence": [ { "id": "XP_020936544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936544" } ] } ], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RE51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE51/entry#names_and_taxonomy" } ] }, { "name": "heat shock transcription factor, Y-linked-like", "type": "synonym", "evidence": [ { "id": "XP_020936544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936544" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE51" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE51", "locus": {} } ], "crossref": [ { "id": "A0A5G2RE51", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RE51", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000041750", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000041750", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110257887", "url": "https://www.ncbi.nlm.nih.gov/gene/110257887", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110257887", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257887", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHIATEQ", "url": "https://omabrowser.org/oma/group/DHIATEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RE51", "url": "https://www.orthodb.org/?gene=A0A5G2RE51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020936544", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936544", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RE51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RE51-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHAPSEIQPVSPKDAPTGSDSSTTSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRMKNASPVSASLLQGCSKKRSRTGGNVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHLISNFPSGYFGLRVEPSPLPTRYQNISPTEGPLSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2RE51-1|A0A5G2RE51_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RE51-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RE51-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE51/entry#A0A5G2RE51-1", "sequence": { "sequence": "MAHAPSEIQPVSPKDAPTGSDSSTTSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRMKNASPVSASLLQGCSKKRSRTGGNVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHLISNFPSGYFGLRVEPSPLPTRYQNISPTEGPLSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2RE51-1|A0A5G2RE51_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RE51-1" }, "locus": { "chromosome": "Y", "start_pos": 23945891, "end_pos": 23944263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089883.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089883.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072856.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072856.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 356, "start_aa": "Thr", "end_pos": 356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr356", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "ssc:110257887", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257887", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q96LI6-1", "protein_name": "Heat shock transcription factor, Y-linked", "gene_name": "HSFY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHVSSETQDVSPKDELTASEASTRSPLCEHTFPGDSDLRSMIEEHAFQVLSQGSLLESPSYTVCVSEPDKDDDFLSLNFPRKLWKIVESDQFKSISWDENGTCIVINEELFKKEILETKAPYRIFQTDAIKSFVRQLNLYGFSKIQQNFQRSAFLATFLSEEKESSVLSKLKFYYNPNFKRGYPQLLVRVKRRIGVKNASPISTLFNEDFNKKHFRAGANMENHNSALAAEASEESLFSASKNLNMPLTRESSVRQIIANSSVPIRSGFPPPSPSTSVGPSEQIATDQHAILNQLTTIHMHSHSTYMQARGHIVNFITTTTSQYHIISPLQNGYFGLTVEPSAVPTRYPLVSVNEAPYRNMLPAGNPWLQMPTIADRSAAPHSRLALQPSPLDKYHPNYN", "length": 401 }, "evidence": [ { "id": "A0A5G2RE51", "url": "https://omabrowser.org/oma/group/A0A5G2RE51/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE51" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE51" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE51", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RE51-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RE51-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RE51" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RE51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE51" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 356 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2REG7-1", "uniprot_ac": "A0A5G2REG7", "uniprot_id": "A0A5G2REG7_PIG", "mass": { "chemical_mass": 11778.0, "monoisotopic_mass": 11778.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Protein S100", "type": "recommended", "evidence": [ { "id": "A0A5G2REG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7/entry#names_and_taxonomy" } ] }, { "name": "S100 calcium-binding protein", "type": "synonym", "evidence": [ { "id": "A0A5G2REG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REG7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7", "locus": {} } ], "crossref": [ { "id": "A0A5G2REG7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2REG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000046234", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000046234", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05022", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05022", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DEYWRLI", "url": "https://omabrowser.org/oma/group/DEYWRLI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639:SF76", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639:SF76", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2REG7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADSYTELEKAVVVLAENFYKYVSKHSLVKNKISKSSFRKMLQKELNHMLTDTGNRKAADKLIQNLDANHDGRISFDEYWTLIGGITSPITNLIRQQEQQSSS", "length": 103, "header": "tr|A0A5G2REG7-1|A0A5G2REG7_PIG Isoform 1 of Protein S100 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2REG7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2REG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7/entry#A0A5G2REG7-1", "sequence": { "sequence": "MADSYTELEKAVVVLAENFYKYVSKHSLVKNKISKSSFRKMLQKELNHMLTDTGNRKAADKLIQNLDANHDGRISFDEYWTLIGGITSPITNLIRQQEQQSSS", "length": 103, "header": "tr|A0A5G2REG7-1|A0A5G2REG7_PIG Isoform 1 of Protein S100 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2REG7-1" }, "locus": { "chromosome": "4", "start_pos": 44238395, "end_pos": 44238087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089765.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089765.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069262.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069262.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REG7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REG7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REG7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REG7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REG7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REG7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7" } ], "pmid": "" }, { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REG7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REG7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2REG7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 103, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2REG7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2REG7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2REG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REG7" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 89, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2REI5-1", "uniprot_ac": "A0A5G2REI5", "uniprot_id": "A0A5G2REI5_PIG", "mass": { "chemical_mass": 32033.0, "monoisotopic_mass": 32033.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2REI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REI5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REI5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5", "locus": {} } ], "crossref": [ { "id": "A0A5G2REI5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2REI5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000040200", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000040200", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2REI5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFVFRAFTTVPEFQALLFLLFLLLYLMILCGNTAIVWAVCTHSSLRTPMYFFLSNLSFLEISGCGAQMFFFLTLGGADCFLLAIMAYDRYVAICHPLRYTVIMTQPLCIQMVAGALGLALFLSLQLTSLIFTLPFCGHLREINHFLCDVPPVLRLACADIHVHQAVLYVVGILVLTVPFLLICVSYAFITSAILRIRSGEGRRRAFSTCSSHITVVLLQYGFCALVYLRPQSSSSVDEDRQFALVYTFVTPLLNPLIYTLRNKDVKGALKKAISCKGTAEALSGNCPM", "length": 288, "header": "tr|A0A5G2REI5-1|A0A5G2REI5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2REI5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2REI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5/entry#A0A5G2REI5-1", "sequence": { "sequence": "MFVFRAFTTVPEFQALLFLLFLLLYLMILCGNTAIVWAVCTHSSLRTPMYFFLSNLSFLEISGCGAQMFFFLTLGGADCFLLAIMAYDRYVAICHPLRYTVIMTQPLCIQMVAGALGLALFLSLQLTSLIFTLPFCGHLREINHFLCDVPPVLRLACADIHVHQAVLYVVGILVLTVPFLLICVSYAFITSAILRIRSGEGRRRAFSTCSSHITVVLLQYGFCALVYLRPQSSSSVDEDRQFALVYTFVTPLLNPLIYTLRNKDVKGALKKAISCKGTAEALSGNCPM", "length": 288, "header": "tr|A0A5G2REI5-1|A0A5G2REI5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2REI5-1" }, "locus": { "chromosome": "2", "start_pos": 12804341, "end_pos": 12802475, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014384.3", "url": "https://www.ensembl.org/id/ENSSSCT00000014384.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073046.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073046.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REI5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REI5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REI5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REI5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REI5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2REI5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 288, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2REI5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2REI5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2REI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REI5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 258, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2REK1-1", "uniprot_ac": "A0A5G2REK1", "uniprot_id": "A0A5G2REK1_PIG", "mass": { "chemical_mass": 34143.0, "monoisotopic_mass": 34143.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110261364", "type": "recommended", "evidence": [ { "id": "A0A5G2REK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1" } ] } ], "protein_names": [ { "name": "Vomeronasal type-1 receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2REK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative pheromone receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1#function" }, { "database": "UniProtKB", "id": "ARBA00003878", "url": "https://www.uniprot.org/uniprotkb/ARBA00003878#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110261364", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000042660", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042660", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2REK1", "url": "https://www.orthodb.org/?gene=A0A5G2REK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24062", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24062", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2REK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTKDWAIGMIFLLQTTAGLLGNCSLLYHFLFLYLTGGTSRSTDLILKHMTLANLLVLLSKGIPETLAALGSKHFLDDFGCKLLFYIHRVSRGVSIGTTCILSVFQVIMISPRDSRWAQLQGKAPRYLGTFSILCWVLNMMLNIFTPFYTTDRWNETSRTKYIDHSYCYSVVYIQNTETVYVPFVLFHDGFRLGLMVWTSGSMVLFLHRHKQRVRYIHGKVQPARPSPETTATKSILVLVCFFVSLWTLSTSIHSCLSVFCNPSFWLKVTSKLIAACFPSVSPYILMRQDSRICRFCFA", "length": 299, "header": "tr|A0A5G2REK1-1|A0A5G2REK1_PIG Isoform 1 of Vomeronasal type-1 receptor OS=Sus scrofa OX=9823 GN=LOC110261364 PE=3 SV=1 CANONICAL=A0A5G2REK1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2REK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1/entry#A0A5G2REK1-1", "sequence": { "sequence": "MDTKDWAIGMIFLLQTTAGLLGNCSLLYHFLFLYLTGGTSRSTDLILKHMTLANLLVLLSKGIPETLAALGSKHFLDDFGCKLLFYIHRVSRGVSIGTTCILSVFQVIMISPRDSRWAQLQGKAPRYLGTFSILCWVLNMMLNIFTPFYTTDRWNETSRTKYIDHSYCYSVVYIQNTETVYVPFVLFHDGFRLGLMVWTSGSMVLFLHRHKQRVRYIHGKVQPARPSPETTATKSILVLVCFFVSLWTLSTSIHSCLSVFCNPSFWLKVTSKLIAACFPSVSPYILMRQDSRICRFCFA", "length": 299, "header": "tr|A0A5G2REK1-1|A0A5G2REK1_PIG Isoform 1 of Vomeronasal type-1 receptor OS=Sus scrofa OX=9823 GN=LOC110261364 PE=3 SV=1 CANONICAL=A0A5G2REK1-1" }, "locus": { "chromosome": "6", "start_pos": 56899265, "end_pos": 56898369, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105340.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105340.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079797.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079797.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1" } ], "pmid": "" }, { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pheromone binding", "id": "GO:0005550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005550", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1" } ], "pmid": "" }, { "name": "pheromone receptor activity", "id": "GO:0016503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016503", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REK1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2REK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REK1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 286, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 23, "end_pos": 25 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2REU3-1", "uniprot_ac": "A0A5G2REU3", "uniprot_id": "A0A5G2REU3_PIG", "mass": { "chemical_mass": 35687.0, "monoisotopic_mass": 35687.0 }, "refseq": { "ac": "XP_003124251", "name": "olfactory receptor 140-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124251" }, "gene_names": [ { "name": "LOC100522923", "type": "recommended", "evidence": [ { "id": "A0A5G2REU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3" } ] }, { "name": "LOC100522923", "type": "synonym", "evidence": [ { "id": "XP_003124251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124251" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2REU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 140-like", "type": "synonym", "evidence": [ { "id": "XP_003124251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124251" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REU3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REU3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100522923", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3", "locus": {} } ], "crossref": [ { "id": "A0A5G2REU3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2REU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522923", "url": "https://www.ncbi.nlm.nih.gov/gene/100522923", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522923", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522923", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2REU3", "url": "https://www.orthodb.org/?gene=A0A5G2REU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003124251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124251", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2REU3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLPLPPNNVTEFVLLGFTQNPHLRKILFMVFLFIFLFTLLSNLFIIITISLSPTLSTPMYFFLANLAVIDAAFSSVTTPKITIDLLYQRTTISWSGCMTQLFLEHILGGSEIIILIAMSYDRYVAICKPLHYTTIMQHGLCRLLVVMAWIGGILHGIVQIHFVLDLPFCGPNVIDHFMCEFFSLFELACTDTYWRGIVVSANSGGMCLLFFFMLLISYMVILRSLKSHGSEGRRKALSTCGSHFTVVVLFFVPCEFIYIRPVATYPVDKLVSLFYGTFTPLLNPIIYTVRNTEVKNAMKCLLKRRVTWVVHDA", "length": 314, "header": "tr|A0A5G2REU3-1|A0A5G2REU3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100522923 PE=3 SV=1 CANONICAL=A0A5G2REU3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2REU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3/entry#A0A5G2REU3-1", "sequence": { "sequence": "MDLPLPPNNVTEFVLLGFTQNPHLRKILFMVFLFIFLFTLLSNLFIIITISLSPTLSTPMYFFLANLAVIDAAFSSVTTPKITIDLLYQRTTISWSGCMTQLFLEHILGGSEIIILIAMSYDRYVAICKPLHYTTIMQHGLCRLLVVMAWIGGILHGIVQIHFVLDLPFCGPNVIDHFMCEFFSLFELACTDTYWRGIVVSANSGGMCLLFFFMLLISYMVILRSLKSHGSEGRRKALSTCGSHFTVVVLFFVPCEFIYIRPVATYPVDKLVSLFYGTFTPLLNPIIYTVRNTEVKNAMKCLLKRRVTWVVHDA", "length": 314, "header": "tr|A0A5G2REU3-1|A0A5G2REU3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100522923 PE=3 SV=1 CANONICAL=A0A5G2REU3-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 486557, "end_pos": 485616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074446.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074446.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069437.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069437.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REU3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522923", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522923", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REU3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REU3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REU3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2REU3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2REU3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2REU3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2REU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REU3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 288, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2REV4-1", "uniprot_ac": "A0A5G2REV4", "uniprot_id": "A0A5G2REV4_PIG", "mass": { "chemical_mass": 44703.0, "monoisotopic_mass": 44703.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2REV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REV4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REV4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REV4", "locus": {} } ], "crossref": [ { "id": "A0A5G2REV4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2REV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000045761", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000045761", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2REV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLKSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRMKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAISTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIAMAPHAIFNQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRGISNFPSGYFGPRVEPSPLPTRYQNISPTEGPLSNPQPAAHPWFPMPMATDTSAALLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2REV4-1|A0A5G2REV4_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2REV4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2REV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REV4/entry#A0A5G2REV4-1", "sequence": { "sequence": "MAQAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLKSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRMKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAISTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIAMAPHAIFNQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRGISNFPSGYFGPRVEPSPLPTRYQNISPTEGPLSNPQPAAHPWFPMPMATDTSAALLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2REV4-1|A0A5G2REV4_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2REV4-1" }, "locus": { "chromosome": "Y", "start_pos": 24009254, "end_pos": 24007626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076390.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076390.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069452.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069452.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 356, "start_aa": "Thr", "end_pos": 356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr356", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REV4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REV4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REV4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REV4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2REV4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2REV4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2REV4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2REV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REV4" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 356 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2REZ2-1", "uniprot_ac": "A0A5G2REZ2", "uniprot_id": "A0A5G2REZ2_PIG", "mass": { "chemical_mass": 34950.0, "monoisotopic_mass": 34950.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110259120", "type": "recommended", "evidence": [ { "id": "A0A5G2REZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2REZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REZ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REZ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259120", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2", "locus": {} } ], "crossref": [ { "id": "A0A5G2REZ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2REZ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000047068", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000047068", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15417", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15417", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2REZ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KPMTGGDNTTNITDFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTIVLTMIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 314, "header": "tr|A0A5G2REZ2-1|A0A5G2REZ2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259120 PE=3 SV=2 CANONICAL=A0A5G2REZ2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2REZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2/entry#A0A5G2REZ2-1", "sequence": { "sequence": "KPMTGGDNTTNITDFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTIVLTMIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 314, "header": "tr|A0A5G2REZ2-1|A0A5G2REZ2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259120 PE=3 SV=2 CANONICAL=A0A5G2REZ2-1" }, "locus": { "chromosome": "AEMK02000637.1", "start_pos": 87656, "end_pos": 86715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088812.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088812.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069502.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069502.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REZ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REZ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REZ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REZ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REZ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2REZ2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2REZ2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2REZ2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2REZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REZ2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 293, "start_aa": "Trp", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 68, "end_pos": 70 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RF06-1", "uniprot_ac": "A0A5G2RF06", "uniprot_id": "A0A5G2RF06_PIG", "mass": { "chemical_mass": 35517.0, "monoisotopic_mass": 35517.0 }, "refseq": { "ac": "XP_020958385", "name": "putative olfactory receptor 56B2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958385" }, "gene_names": [ { "name": "LOC110262329", "type": "synonym", "evidence": [ { "id": "XP_020958385", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958385" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RF06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06/entry#names_and_taxonomy" } ] }, { "name": "putative olfactory receptor 56B2", "type": "synonym", "evidence": [ { "id": "XP_020958385", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958385" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06", "locus": {} } ], "crossref": [ { "id": "A0A5G2RF06", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RF06", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15223", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15223", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110262329", "url": "https://www.ncbi.nlm.nih.gov/gene/110262329", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110262329", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110262329", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KATMFMA", "url": "https://omabrowser.org/oma/group/KATMFMA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RF06", "url": "https://www.orthodb.org/?gene=A0A5G2RF06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020958385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958385", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RF06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RF06-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFQELSGANSSKGQVSEFVLMGFPGIHTWQHWLSLPLAWLYLLALSANILILIIISHEATLHQPMYHFLGILAVVDMGLATTIMPKILAILWFDAKAISLPECFLQMYVIHCFVAMESGVFVCMAMDRYVAICRPLHYTSIVTRSFVAKATVFMALRSCLLTIPVPVLAAQRQYCSRNEIEHCLCSNRGVTRLACDDRTISSMYQLLLAWTLMGSDLGLIMLSYALILHSVLKLNSAEAASKALSTCTSHLILILFFYTVIVVISVTHSAAMTVPLIPVLLNVLHNVIPPALNPVVYALKNKELRHGLYKVLKLKVKDN", "length": 319, "header": "tr|A0A5G2RF06-1|A0A5G2RF06_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RF06-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RF06-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06/entry#A0A5G2RF06-1", "sequence": { "sequence": "MFQELSGANSSKGQVSEFVLMGFPGIHTWQHWLSLPLAWLYLLALSANILILIIISHEATLHQPMYHFLGILAVVDMGLATTIMPKILAILWFDAKAISLPECFLQMYVIHCFVAMESGVFVCMAMDRYVAICRPLHYTSIVTRSFVAKATVFMALRSCLLTIPVPVLAAQRQYCSRNEIEHCLCSNRGVTRLACDDRTISSMYQLLLAWTLMGSDLGLIMLSYALILHSVLKLNSAEAASKALSTCTSHLILILFFYTVIVVISVTHSAAMTVPLIPVLLNVLHNVIPPALNPVVYALKNKELRHGLYKVLKLKVKDN", "length": 319, "header": "tr|A0A5G2RF06-1|A0A5G2RF06_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RF06-1" }, "locus": { "chromosome": "9", "start_pos": 3999342, "end_pos": 3998386, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075933.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075933.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073296.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073296.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110262329", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110262329", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M0RB85-1", "protein_name": "Olfactory receptor family 56 subfamily B member 2", "gene_name": "Or56b2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQILRDSNSSRFQVSEFILMGFPGIHSWQHWLSLPLALLYVLALIANILIVSIIYQEASLHQPMYYFLGILAIVDMGLATTIMPKILAILWFNDNNISLPECFAQMYTIHCFVAMESGIFVCMAIDRYVAICRPLRYSSIVTESFVIKATVFMTFRNFVAPISVPVLAAQRNYCSQNKIEHCLCSNLGVTSLACDDRKINSINQLFLAWTLMGSDLGLIIVSYALILRSVLRLNSAEAASKALSTCTSHLILIFFFYTVIVVMSITHSVGMKIPLIPVLLNVLHNVIPPALNPMVYALKNKELKQGLYKVLRLDVKGG", "length": 319 }, "evidence": [ { "id": "A0A5G2RF06", "url": "https://omabrowser.org/oma/group/A0A5G2RF06/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99NH4-1", "protein_name": "Olfactory receptor family 56 subfamily B member 2", "gene_name": "Or56b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQILRDSNSSRFQVSEFILMGFPGIHSWQHWLSLPLALLYVLALIANILIVTVIYQEASLHQPMYHFLGILAIVDVGLATTIMPKILAILWFNDNNISLPECFAQMYAIHCFVAMESGIFVCMAIDRYVAICKPLRYSSIVTESFVVKATVIMAIRNFVAPMSVPVLAAQRNYCFQNKIEHCLCSNLGVTSLACDDRKINSINQLFLAWTLMGSDLALIMISYALILRSVLRLNSAEAASKALSTCTSHLILIFFFYTVIVVISITHSVGIKIPLIPVLLNVLHNVIPPALNPMVYALKNKELKQGLYKVLRLDVKEG", "length": 319 }, "evidence": [ { "id": "A0A5G2RF06", "url": "https://omabrowser.org/oma/group/A0A5G2RF06/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF06", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RF06-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 319, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RF06-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RF06" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RF06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF06" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 297, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RF19-1", "uniprot_ac": "A0A5G2RF19", "uniprot_id": "A0A5G2RF19_PIG", "mass": { "chemical_mass": 55766.0, "monoisotopic_mass": 55766.0 }, "refseq": {}, "gene_names": [ { "name": "CYP2J33", "type": "recommended", "evidence": [ { "id": "A0A5G2RF19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19" } ] } ], "protein_names": [ { "name": "Cytochrome P450 2J2", "type": "recommended", "evidence": [ { "id": "A0A5G2RF19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CYP2J33", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19", "locus": {} } ], "crossref": [ { "id": "A0A5G2RF19", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RF19", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003825", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003825", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300:SF177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300:SF177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RF19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RF19-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTQALGSLAEALWTALHPSTLLLGAVTFLFFADFLKKRRPKNYPPGPLRLPFVGNLFHLDFEKAHLSLQRFVKKYGNIFSLDLCALSAVVVTGLPLIKEVLVHQNQKFANRPILPIQDRVFKNKGVVTSSGQVWKEQRRFTLTTLRNFGLGKKSLEERIQEEAQYLTQAIGEENGQPFNPQFKISNAVSNIICSITFGKRFDYQDDQFQELLRLLREVTHLQTLLWCQLFNVFPRIMKFLPGPHQTLFSDWEKLEMFIARVIENHRRDWNPAEARDFIDAYLQEIEKNKGNATSSFHEENLICSTLDLLFAGTDTTLITLRWGLLYMALHPEIQEKVQAEIDRVLGQSQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVVEDTTLAGYHLPKGTMIMTNLTALHRDPTEWATPDTFNPEHFLENGKFKKREAFLPFSIALPHSSPCGALLQQEGLRLALPSLAPSCCCLPPGFPVQGITRTDALTS", "length": 491, "header": "tr|A0A5G2RF19-1|A0A5G2RF19_PIG Isoform 1 of Cytochrome P450 2J2 OS=Sus scrofa OX=9823 GN=CYP2J33 PE=3 SV=1 CANONICAL=A0A5G2RF19-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RF19-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19/entry#A0A5G2RF19-1", "sequence": { "sequence": "MTQALGSLAEALWTALHPSTLLLGAVTFLFFADFLKKRRPKNYPPGPLRLPFVGNLFHLDFEKAHLSLQRFVKKYGNIFSLDLCALSAVVVTGLPLIKEVLVHQNQKFANRPILPIQDRVFKNKGVVTSSGQVWKEQRRFTLTTLRNFGLGKKSLEERIQEEAQYLTQAIGEENGQPFNPQFKISNAVSNIICSITFGKRFDYQDDQFQELLRLLREVTHLQTLLWCQLFNVFPRIMKFLPGPHQTLFSDWEKLEMFIARVIENHRRDWNPAEARDFIDAYLQEIEKNKGNATSSFHEENLICSTLDLLFAGTDTTLITLRWGLLYMALHPEIQEKVQAEIDRVLGQSQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVVEDTTLAGYHLPKGTMIMTNLTALHRDPTEWATPDTFNPEHFLENGKFKKREAFLPFSIALPHSSPCGALLQQEGLRLALPSLAPSCCCLPPGFPVQGITRTDALTS", "length": 491, "header": "tr|A0A5G2RF19-1|A0A5G2RF19_PIG Isoform 1 of Cytochrome P450 2J2 OS=Sus scrofa OX=9823 GN=CYP2J33 PE=3 SV=1 CANONICAL=A0A5G2RF19-1" }, "locus": { "chromosome": "6", "start_pos": 152574740, "end_pos": 152553598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071195.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071195.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073317.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073317.1" } ] } }, { "isoform_ac": "A0A8W4FKK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19/entry#A0A8W4FKK3-1", "sequence": { "sequence": "MTQALGSLAEALWTALHPSTLLLGAVTFLFFADFLKKRRPKNYPPGPLRLPFVGNLFHLDFEKAHLSLQRFVKKYGNIFSLDLCALSAVVVTGLPLIKEVLVHQNQKFANRPILPIQDRVFKNKGVVTSSGQVWKEQRRFTLTTLRNFGLGKKSLEERIQEEAQYLTQAIGEENGQPFNPQFKISNAVSNIICSITFGKRFDYQDDQFQELLRLLREVTHLQTLLWCQLFNVFPRIMKFLPGPHQTLFSDWEKLEMFIARVIENHRRDWNPAEARDFIDAYLQEIEKVRKPELFPEFNSYIGSEGILLSYCYCNKLLQIWGTSFAFPEKVQAEIDRVLGQSQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVVEDTTLAGYHLPKGTMIMTNLTALHRDPTEWATPDTFNPEHFLENGKFKKREAFLPFSIALPHSSPCGALLQQEGLRLALPSLAPSCCCLPPGFPVQGITRTDALTS", "length": 484, "header": "tr|A0A8W4FKK3-1|A0A5G2RF19_PIG Computationally mapped isoform of Cytochrome P450 2J2 OS=Sus scrofa OX=9823 GN=CYP2J33 PE=3 SV=1 CANONICAL=A0A5G2RF19-1" }, "locus": { "chromosome": "6", "start_pos": 152574740, "end_pos": 152553598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092520.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092520.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079752.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079752.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKK3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19" } ], "pmid": "" }, { "name": "organic acid metabolic process", "id": "GO:0006082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006082", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RF19-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 491, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RF19-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RF19" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 291, "end_pos": 293 }, { "start_pos": 404, "end_pos": 406 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RF90-1", "uniprot_ac": "A0A5G2RF90", "uniprot_id": "A0A5G2RF90_PIG", "mass": { "chemical_mass": 61684.0, "monoisotopic_mass": 61684.0 }, "refseq": {}, "gene_names": [ { "name": "DCP1A", "type": "recommended", "evidence": [ { "id": "A0A5G2RF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ] } ], "protein_names": [ { "name": "5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase", "type": "recommended", "evidence": [ { "id": "A0A5G2RF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90/entry#names_and_taxonomy" } ] }, { "name": "3.6.1.62", "type": "synonym", "evidence": [ { "id": "A0A5G2RF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DCP1A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90", "locus": { "chromosome": "13", "start_pos": 35391320, "end_pos": 35455743, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000022616", "url": "https://www.ensembl.org/id/ENSSSCG00000022616" } ] } } ], "crossref": [ { "id": "A0A5G2RF90", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RF90", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000022616", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022616", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09804", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09804", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR010334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16290:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16290:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06058", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06058", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-430039", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-430039", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-450385", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450385", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-450513", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450513", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "67484", "url": "https://www.rhea-db.org/rhea/67484", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RF90-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESLSRAGQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQWEKTDIEGTLFVYRRSASPYHGFTIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASLSIYSIWFYDKNDCHRIAKLMADVLEEETRRSQQAARDKQSPNQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQISNLGSTETLEETPSGLQDKSALSGHKHLTVEELFGTSLPKEQPTVVGLESEEVEKLPGDASQKEPSSFLPFSFEPSGGGPQSENMGIRPAAHHSVQPEVTTPVLITPASITQSSEKQAPSYAIPLHPVLSPTLPAEASTAQAPPSLPRSTTMMQAVKTTPRQRSPLSSQPVPELSQASLAASQSPFRAPLNVTNTASTSLPSVDLLQKLRLTQQHDQIQTQSLGKGAVAPSFSPAAGQLATPESFIEPPPKTAAARASASLSNMVLAPLQSMQQNQDPEVFAQPKVLSSAIPVAGPALVTATTSAVSSVLLSPSVFQQTVTRSSDLERKASSPSPLTVGTSENQRKPSIILSKSQLQDTLIHLIKKQELLDELLHFARAS", "length": 569, "header": "tr|A0A5G2RF90-1|A0A5G2RF90_PIG Isoform 1 of 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase OS=Sus scrofa OX=9823 GN=DCP1A PE=3 SV=1 CANONICAL=A0A5G2RF90-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QFQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90/entry#A0A5G2QFQ6-1", "sequence": { "sequence": "MESLSRAGQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQWVSAARSASPYHGFTIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASLSIYSIWFYDKNDCHRIAKLMADVLEEETRRSQQAARDKQSPNQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQISNLGSTETLEETPSGLQDKSALSGHKHLTVEELFGTSLPKEQPTVVGLESEEVEKLPGDASQKEPSSFLPFSFEPSGGGPQSENMGIRPAAHHSVQPEVTTPVLITPASITQSSEKQAPSYAIPLHPVLSPTLPAEASTAQAPPSLPRSTTMMQAVKTTPRQRSPLSSQPVPELSQASLAASQSPFRAPLNVTNTASTSLPSVDLLQKLRLTQQHDQIQTQSLGKGAVAPSFSPAAGQLATPESFIEPPPKTAAARASASLSNMVLAPLQSMQQNQDPEVFAQPKVLSSAIPVAGPALVTATTSAVSSVLLSPSVFQQTVTRSSDLERKASSPSPLTVGTSENQRKPSIILSKSQLQDTLIHLIKVCRISI", "length": 551, "header": "tr|A0A5G2QFQ6-1|A0A5G2QFQ6_PIG Computationally mapped isoform of 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase OS=Sus scrofa OX=9823 GN=DCP1A PE=3 SV=2 CANONICAL=A0A5G2RF90-1" }, "locus": { "chromosome": "13", "start_pos": 35455635, "end_pos": 35396846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086671.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086671.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063567.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063567.2" } ] } }, { "isoform_ac": "A0A5G2RF90-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90/entry#A0A5G2RF90-1", "sequence": { "sequence": "MESLSRAGQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQWEKTDIEGTLFVYRRSASPYHGFTIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASLSIYSIWFYDKNDCHRIAKLMADVLEEETRRSQQAARDKQSPNQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQISNLGSTETLEETPSGLQDKSALSGHKHLTVEELFGTSLPKEQPTVVGLESEEVEKLPGDASQKEPSSFLPFSFEPSGGGPQSENMGIRPAAHHSVQPEVTTPVLITPASITQSSEKQAPSYAIPLHPVLSPTLPAEASTAQAPPSLPRSTTMMQAVKTTPRQRSPLSSQPVPELSQASLAASQSPFRAPLNVTNTASTSLPSVDLLQKLRLTQQHDQIQTQSLGKGAVAPSFSPAAGQLATPESFIEPPPKTAAARASASLSNMVLAPLQSMQQNQDPEVFAQPKVLSSAIPVAGPALVTATTSAVSSVLLSPSVFQQTVTRSSDLERKASSPSPLTVGTSENQRKPSIILSKSQLQDTLIHLIKKQELLDELLHFARAS", "length": 569, "header": "tr|A0A5G2RF90-1|A0A5G2RF90_PIG Isoform 1 of 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase OS=Sus scrofa OX=9823 GN=DCP1A PE=3 SV=1 CANONICAL=A0A5G2RF90-1" }, "locus": { "chromosome": "13", "start_pos": 35455635, "end_pos": 35392513, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082994.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082994.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073422.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073422.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-430039", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-430039", "resource": "Reactome", "description": "mRNA decay by 5' to 3' exoribonuclease" }, { "id": "R-SSC-450385", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450385", "resource": "Reactome", "description": "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" }, { "id": "R-SSC-450513", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450513", "resource": "Reactome", "description": "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "deadenylation-dependent decapping of nuclear-transcribed mRNA", "id": "GO:0000290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000290", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "pmid": "" }, { "name": "protein localization to cytoplasmic stress granule", "id": "GO:1903608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903608", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "pmid": "" }, { "name": "deadenylation-independent decapping of nuclear-transcribed mRNA", "id": "GO:0031087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "pmid": "" }, { "name": "5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity", "id": "GO:0140933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140933", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RF90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF90" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "67484", "name": "", "equation": "a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = N(7)-methyl-GDP + a 5'-end phospho-ribonucleoside in mRNA + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "67484", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67484" } ] }, { "id": "R-SSC-429860", "name": "DCP1-DCP2 complex decaps mRNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-430004" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-429860", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429860" } ] }, { "id": "R-SSC-450431", "name": "ZFP36 (TTP) recruits RNA degradation activities", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-450431", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450431" } ] }, { "id": "R-SSC-450488", "name": "BRF1 Complex recruits RNA degradation activities", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-450488", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450488" } ] }, { "id": "R-SSC-927813", "name": "p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-927813", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-927813" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-430004", "participant_name": "7-MeGDP [cytosol]", "crossref": [ { "id": "HMDB0001107", "database": "HMDB Metabolite", "url": "" }, { "id": "20794", "database": "ChEBI", "url": "" }, { "id": "ZINC000018130229", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RF90-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 569, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RF90-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RF90" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RFG8-1", "uniprot_ac": "A0A5G2RFG8", "uniprot_id": "A0A5G2RFG8_PIG", "mass": { "chemical_mass": 35712.0, "monoisotopic_mass": 35712.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8", "locus": {} } ], "crossref": [ { "id": "A0A5G2RFG8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RFG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPGKNITGISEFFLLGFSEGAAMQPLIFGLFLSMYLITVFGNLLLILAVSSDSRLHIPMYFFLSNLSSVDICFISTTIPKMLWNIYSKRQVITYAGCITQMYFFLLFAGLDDLLLNVMAYDRFVAICHPLHYRVIMEPQLSGILVMVSWIISVLHSLLQTLMTLRLSFCREVKMPHYFCELKQLIQLVCSDKCLNNMVMNFAAGLLGGVPLAGILYSYYKIVASIRRISSAQGKNKAFSTCASHLSVVSLFFSTSLGVYLSSSATHSSYLIEINSVMYTVVTPILKPFIYSLRNKHIKRALKAFFHMAAIRSPVDLG", "length": 318, "header": "tr|A0A5G2RFG8-1|A0A5G2RFG8_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RFG8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RFG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8/entry#A0A5G2RFG8-1", "sequence": { "sequence": "MDPGKNITGISEFFLLGFSEGAAMQPLIFGLFLSMYLITVFGNLLLILAVSSDSRLHIPMYFFLSNLSSVDICFISTTIPKMLWNIYSKRQVITYAGCITQMYFFLLFAGLDDLLLNVMAYDRFVAICHPLHYRVIMEPQLSGILVMVSWIISVLHSLLQTLMTLRLSFCREVKMPHYFCELKQLIQLVCSDKCLNNMVMNFAAGLLGGVPLAGILYSYYKIVASIRRISSAQGKNKAFSTCASHLSVVSLFFSTSLGVYLSSSATHSSYLIEINSVMYTVVTPILKPFIYSLRNKHIKRALKAFFHMAAIRSPVDLG", "length": 318, "header": "tr|A0A5G2RFG8-1|A0A5G2RFG8_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RFG8-1" }, "locus": { "chromosome": "2", "start_pos": 62768479, "end_pos": 62741429, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080022.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080022.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073547.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073547.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RFG8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 318, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RFG8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFG8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFG8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 66, "end_pos": 68 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RFJ2-1", "uniprot_ac": "A0A5G2RFJ2", "uniprot_id": "A0A5G2RFJ2_PIG", "mass": { "chemical_mass": 34673.0, "monoisotopic_mass": 34673.0 }, "refseq": { "ac": "XP_020936940", "name": "olfactory receptor 12D2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936940" }, "gene_names": [ { "name": "LOC110258123", "type": "recommended", "evidence": [ { "id": "A0A5G2RFJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2" } ] }, { "name": "LOC110258123", "type": "synonym", "evidence": [ { "id": "XP_020936940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936940" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RFJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 12D2-like", "type": "synonym", "evidence": [ { "id": "XP_020936940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936940" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110258123", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2", "locus": {} } ], "crossref": [ { "id": "A0A5G2RFJ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15915", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15915", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110258123", "url": "https://www.ncbi.nlm.nih.gov/gene/110258123", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110258123", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258123", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CINYISH", "url": "https://omabrowser.org/oma/group/CINYISH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RFJ2", "url": "https://www.orthodb.org/?gene=A0A5G2RFJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020936940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936940", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNQTSVTEFLLLGVTDIQELQPLLFVLFLAIYLVIVAGNGAILMVVISEPRLHSPMYFFLGNLSCLDICYSTVTLPKMLGNFLSSHKAISFWGCISQLHFFHFLGSTEALLLAVMAFDRFVAICKPLRYTLIMNPQVCTQMAVTVWITGFFHALMHSIMTSRLHFCGSNHIHHFFCDIKPLLKLACGNIELNQWLLNTVTGTMAMGPFFLTLLSYGYIITHLSFKTHSCSMLHKALSICASHFMVVFLFFAPVVFTYICTTSGGSMDQDRIIAIMYSVVTPVLNPLIYTLRNKQVKGALSKLVKRRF", "length": 308, "header": "tr|A0A5G2RFJ2-1|A0A5G2RFJ2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258123 PE=3 SV=1 CANONICAL=A0A5G2RFJ2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RFJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2/entry#A0A5G2RFJ2-1", "sequence": { "sequence": "MPNQTSVTEFLLLGVTDIQELQPLLFVLFLAIYLVIVAGNGAILMVVISEPRLHSPMYFFLGNLSCLDICYSTVTLPKMLGNFLSSHKAISFWGCISQLHFFHFLGSTEALLLAVMAFDRFVAICKPLRYTLIMNPQVCTQMAVTVWITGFFHALMHSIMTSRLHFCGSNHIHHFFCDIKPLLKLACGNIELNQWLLNTVTGTMAMGPFFLTLLSYGYIITHLSFKTHSCSMLHKALSICASHFMVVFLFFAPVVFTYICTTSGGSMDQDRIIAIMYSVVTPVLNPLIYTLRNKQVKGALSKLVKRRF", "length": 308, "header": "tr|A0A5G2RFJ2-1|A0A5G2RFJ2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258123 PE=3 SV=1 CANONICAL=A0A5G2RFJ2-1" }, "locus": { "chromosome": "AEMK02000453.1", "start_pos": 77261, "end_pos": 76338, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072217.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072217.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073587.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073587.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110258123", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258123", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RFJ2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 308, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RFJ2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RFJ2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RFJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFJ2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RG11-1", "uniprot_ac": "A0A5G2RG11", "uniprot_id": "A0A5G2RG11_PIG", "mass": { "chemical_mass": 15393.0, "monoisotopic_mass": 15393.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "H2B clustered histone 15", "type": "synonym", "evidence": [ { "id": "A0A5G2RG11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11", "locus": {} } ], "crossref": [ { "id": "A0A5G2RG11", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RG11", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044013", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044013", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22910", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22910", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000558", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RG11", "url": "https://www.orthodb.org/?gene=A0A5G2RG11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00125", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG11-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEPSKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRCCCPGSWPSTPCPRAPRLSPSTPAPSEPACSGATELCPSLLA", "length": 142, "header": "tr|A0A5G2RG11-1|A0A5G2RG11_PIG Isoform 1 of H2B clustered histone 15 OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RG11-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RG11-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11/entry#A0A5G2RG11-1", "sequence": { "sequence": "MPEPSKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRCCCPGSWPSTPCPRAPRLSPSTPAPSEPACSGATELCPSLLA", "length": 142, "header": "tr|A0A5G2RG11-1|A0A5G2RG11_PIG Isoform 1 of H2B clustered histone 15 OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RG11-1" }, "locus": { "chromosome": "7", "start_pos": 21609601, "end_pos": 21606836, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075485.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075485.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073852.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073852.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "antibacterial humoral response", "id": "GO:0019731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019731", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" } ], "pmid": "" }, { "name": "antimicrobial humoral immune response mediated by antimicrobial peptide", "id": "GO:0061844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061844", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" } ], "pmid": "" }, { "name": "innate immune response in mucosa", "id": "GO:0002227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002227", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG11", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RG11-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 142, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RG11-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RG11" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RG11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG11" }, { "id": "PF00125", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Core Histone H2A/H2B/H3", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 100, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RG31-1", "uniprot_ac": "A0A5G2RG31", "uniprot_id": "A0A5G2RG31_PIG", "mass": { "chemical_mass": 25436.0, "monoisotopic_mass": 25436.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100517900", "type": "recommended", "evidence": [ { "id": "A0A5G2RG31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RG31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100517900", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31", "locus": {} } ], "crossref": [ { "id": "A0A5G2RG31", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RG31", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RG31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG31-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEALWTNNGSITFSECLAQLYFFAVFADMDNLLLTVMAIDRYAAVCHPLHYPLIMTLGRCGLLVGGSWGVALSVSLVHALLLSQLAFYTHQEIPHFFCDFGPLFQLSCSDAHLNENLMMVLAGLLGISPLLCTVSSYVHILHAVAKAPSAQGKKKALVTCSSHLSVVILFYSTVFATYLKPPSTSHSSGELVAAVMYTLVTPTLNPFIYSLRNKDVKSSLKRVWGIESSWD", "length": 232, "header": "tr|A0A5G2RG31-1|A0A5G2RG31_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100517900 PE=3 SV=1 CANONICAL=A0A5G2RG31-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RG31-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31/entry#A0A5G2RG31-1", "sequence": { "sequence": "MLEALWTNNGSITFSECLAQLYFFAVFADMDNLLLTVMAIDRYAAVCHPLHYPLIMTLGRCGLLVGGSWGVALSVSLVHALLLSQLAFYTHQEIPHFFCDFGPLFQLSCSDAHLNENLMMVLAGLLGISPLLCTVSSYVHILHAVAKAPSAQGKKKALVTCSSHLSVVILFYSTVFATYLKPPSTSHSSGELVAAVMYTLVTPTLNPFIYSLRNKDVKSSLKRVWGIESSWD", "length": 232, "header": "tr|A0A5G2RG31-1|A0A5G2RG31_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100517900 PE=3 SV=1 CANONICAL=A0A5G2RG31-1" }, "locus": { "chromosome": "AEMK02000223.1", "start_pos": 41765, "end_pos": 41070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093529.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093529.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076742.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076742.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RG31-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 232, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RG31-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RG31" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RG31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG31" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 210, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RG89-1", "uniprot_ac": "A0A5G2RG89", "uniprot_id": "A0A5G2RG89_PIG", "mass": { "chemical_mass": 49465.0, "monoisotopic_mass": 49465.0 }, "refseq": { "ac": "XP_020943566", "name": "UMP-CMP kinase 2, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943566" }, "gene_names": [ { "name": "CMPK2", "type": "recommended", "evidence": [ { "id": "A0A5G2RG89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ] }, { "name": "CMPK2", "type": "synonym", "evidence": [ { "id": "XP_020943566", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943566" } ] } ], "protein_names": [ { "name": "UMP-CMP kinase 2, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A5G2RG89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89/entry#names_and_taxonomy" } ] }, { "name": "2.7.4.14", "type": "synonym", "evidence": [ { "id": "A0A5G2RG89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89/entry#names_and_taxonomy" } ] }, { "name": "Nucleoside-diphosphate kinase", "type": "synonym", "evidence": [ { "id": "A0A5G2RG89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89/entry#names_and_taxonomy" } ] }, { "name": "UMP-CMP kinase 2, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_020943566", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943566" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CMPK2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89", "locus": { "chromosome": "3", "start_pos": 128917871, "end_pos": 128903616, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008647", "url": "https://www.ensembl.org/id/ENSSSCG00000008647" } ] } } ], "crossref": [ { "id": "A0A5G2RG89", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RG89", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008647", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008647", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100623872", "url": "https://www.ncbi.nlm.nih.gov/gene/100623872", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623872", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623872", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ECTSLIP", "url": "https://omabrowser.org/oma/group/ECTSLIP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RG89", "url": "https://www.orthodb.org/?gene=A0A5G2RG89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10344:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10344:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02223", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02223", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020943566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943566", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11600", "url": "https://www.rhea-db.org/rhea/11600", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "18113", "url": "https://www.rhea-db.org/rhea/18113", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25094", "url": "https://www.rhea-db.org/rhea/25094", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44640", "url": "https://www.rhea-db.org/rhea/44640", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG89-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S9L3", "url": "https://www.uniprot.org/uniprotkb/F1S9L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S9L3-1", "url": "https://www.uniprot.org/uniprotkb/F1S9L3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFGRRPRAPLLLARLSGLRRGACAPAMELPRCFALELPGCTLAHFAVDDEAPGAHPDPHAAALLGPPGRSYSLSVPVAEGAGCAARVRAARLHQRLLHQLRGSPFQLCQLHRLLCYHPGGGAGGLQHGFLLHDPRDSPDTRSALLALLDAYRDAPRPLLAEFAGDAGRQLWRRPWELQDEHGWRQVGSELVVPAPDPALHPVVPDLPSCGVFPHREAARAVLEACTSFIPEAQAVLDLVDRCPEQVQKGKFPVIAIEGLDATGKTTVTQSVSDSLKAVLLKSPPACISQWRKIFDDEPTIIRRAFYSLGNYIVASEIAKESTKSPVIIDRYWHSTATYTIASEVSGGLQHLPPTHHPIYQWPRDLLKPDLVLLLTVSPEERMKRIEGRGLERTREEVELETDSIYRQKVEVSYQRMEDPGCHVVDASPSREKVLQTVLSIIQNNCNVL", "length": 449, "header": "tr|A0A5G2RG89-1|A0A5G2RG89_PIG Isoform 1 of UMP-CMP kinase 2, mitochondrial OS=Sus scrofa OX=9823 GN=CMPK2 PE=1 SV=1 CANONICAL=A0A5G2RG89-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RG89-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89/entry#A0A5G2RG89-1", "sequence": { "sequence": "MAFGRRPRAPLLLARLSGLRRGACAPAMELPRCFALELPGCTLAHFAVDDEAPGAHPDPHAAALLGPPGRSYSLSVPVAEGAGCAARVRAARLHQRLLHQLRGSPFQLCQLHRLLCYHPGGGAGGLQHGFLLHDPRDSPDTRSALLALLDAYRDAPRPLLAEFAGDAGRQLWRRPWELQDEHGWRQVGSELVVPAPDPALHPVVPDLPSCGVFPHREAARAVLEACTSFIPEAQAVLDLVDRCPEQVQKGKFPVIAIEGLDATGKTTVTQSVSDSLKAVLLKSPPACISQWRKIFDDEPTIIRRAFYSLGNYIVASEIAKESTKSPVIIDRYWHSTATYTIASEVSGGLQHLPPTHHPIYQWPRDLLKPDLVLLLTVSPEERMKRIEGRGLERTREEVELETDSIYRQKVEVSYQRMEDPGCHVVDASPSREKVLQTVLSIIQNNCNVL", "length": 449, "header": "tr|A0A5G2RG89-1|A0A5G2RG89_PIG Isoform 1 of UMP-CMP kinase 2, mitochondrial OS=Sus scrofa OX=9823 GN=CMPK2 PE=1 SV=1 CANONICAL=A0A5G2RG89-1" }, "locus": { "chromosome": "3", "start_pos": 128916330, "end_pos": 128903661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088701.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088701.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073978.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073978.1" } ] } }, { "isoform_ac": "F1S9L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89/entry#F1S9L3-1", "sequence": { "sequence": "MAFGRRPRAPLLLARLSGLRRGACAPAMELPRCFALELPGCTLAHFAVDDEAPGAHPDPHAAALLGPPGRSYSLSPFQLCQLHRLLCYHPGGGAGGLQHGFLLHDPRDSPDTRSALLALLDAYRDAPRPLLAEFAGDAGRQLWRRPWELQDEHGWRQVGSELVVPAPDPALHPVVPDLPSCGVFPHREAARAVLEACTSFIPEAQAVLDLVDRCPEQVQKGKFPVIAIEGLDATGKTTVTQSVSDSLKAVLLKSPPACISQWRKIFDDEPTIIRRAFYSLGNYIVASEIAKESTKSPVIIDRYWHSTATYTIASEVSGGLQHLPPTHHPIYQWPRDLLKPDLVLLLTVSPEERMKRIEGRGLERTREEVELETDSIYRQKVEVSYQRMEDPGCHVVDASPSREKVLQTVLSIIQNNCNVL", "length": 420, "header": "tr|F1S9L3-1|A0A5G2RG89_PIG Computationally mapped isoform of UMP-CMP kinase 2, mitochondrial OS=Sus scrofa OX=9823 GN=CMPK2 PE=1 SV=4 CANONICAL=A0A5G2RG89-1" }, "locus": { "chromosome": "3", "start_pos": 128916330, "end_pos": 128903661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009460.4", "url": "https://www.ensembl.org/id/ENSSSCT00000009460.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009217.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009217.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S9L3", "url": "https://www.uniprot.org/uniprotkb/F1S9L3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623872", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623872", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZC63-1", "protein_name": "UMP-CMP kinase 2, mitochondrial", "gene_name": "Cmpk2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALISCPRAPLWLGRLSRRLCARHRACTGTMARPRRFTVELPDCSLTHFVLGDAAGHRDARLTELLGPPGRSYALCVPLVPGEGCGPRVQAARVYQRLQLQLRQGPLQRCELSKLLGYGPGDQASEAQHGFLLRDPSDHPDTRQDLLQLLGSCQEATRLHLAEFQADSQGLLWQRLWELQGDRQVQVDCACVLPAPEPHLHPLLPDLLNSAVFQDRDAARAVLEECTSFIPEAREVLDLVDQCPREIQKGKFQVIAIEGLDATGKTTLTQSVSESLQAVLLQSPPPCISQWRKLFDDEPTIIRRAFYSLGNYLVASEIAKQSAKFPVIVDRYWHSTATYAIATEVSGGLQYLPPAHHPVYQWPRDLLKPDLVLLLTVNSEERVRRLQGRGQEKTKEEAELEVNSVFRQKVEATYQRMENPSCRLVDASPSRETVLQTVLQLIQRAGH", "length": 447 }, "evidence": [ { "id": "A0A5G2RG89", "url": "https://omabrowser.org/oma/group/A0A5G2RG89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N2W6-1", "protein_name": "UMP-CMP kinase 2, mitochondrial", "gene_name": "CMPK2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKRYTRARAHARVPYPGTSNTGGIIQPGAWGHRPASHRGSLSEAARRPGLCGCPSGPSWRQPARGATSRSGGGGGETEEVAPTRAPPTSRRRRRRRRRRRRRRRFVFVSTGVPPAGSQVSFPQRPGRHREAPMTFGRHPRARRLLARLSGRRRGACARAMEPPRCFALELPGCTLAHFAVGELAPGARPDPRVAALLGPPGRSYSLSVPETGGVGARVRAARLHQHLRQQLRRGPFQRCELRRLLGYRPDGGAGALQHGFLLRDPRDSPDTRQALLELLDACPEAPRPLLAEFSGDRLCQLWQRPWERRDGRGWRQLGGERVGPAPEPALHPVVPDLPSAGVFPHREAACAVLEACTSFIPEAREVLDLVDQCPEQVQKGRFPVIVIEGLDATGKTTVTQSVSDSLKAVLLKSPPSCISQWRKIFDDEPTIIRRAFYSLGNYIVASEIAKESTKSPVVVDRYWHSTATYAIATEVSGGLQHLPPIHHPIYQWPRDLLKPDLILLLTVSPEERMQRIEGRGMEKTREEAELETNSIFRQKVEVCYQRMENPGCHVVDASPSREKVLQMVLSVIQNNCNYL", "length": 579 }, "evidence": [ { "id": "A0A5G2RG89", "url": "https://omabrowser.org/oma/group/A0A5G2RG89/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3U5Q7-1", "protein_name": "UMP-CMP kinase 2, mitochondrial", "gene_name": "Cmpk2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALISRPRAPLWLGRLSRRLCGRHQACMGTMARPRRFTVELPDCSLTHFVLGDATDHRDARLAELLGPPGRSYALCVPLAPGEGCGPRVQAARVHHRLLQQLRRGPLQRCQLSKLLGYGPGDQAGEAQHGFLLRDPCDHPDTRRDLLQLLGSCQEAARPQLAEFQADSQGLLWQRLWELQGDRQVQVDCACVLPAQEPHLHPLLPDLLNSAVFQDRDAARAVLEECTSFIPEARAVLDLVDQCPKEVQKGKFQVIAIEGLDATGKTTLTQSVSESLKAVLLQSPPPCISQWRKIFDDEPTIIRRAFYSLGNYLVASEIAKESTNFPVIVDRYWHSTATYAIATEVSGGLQYLPPAHHPVYQWPGDLLKPDLVLLLTVNSEERVRRLQGRGQEKTKEEAELEANNVFRQKVEMTYQRMENPSCHLVDASPSRETVLQKVLELIQSSGR", "length": 447 }, "evidence": [ { "id": "A0A5G2RG89", "url": "https://omabrowser.org/oma/group/A0A5G2RG89/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5EBM0-1", "protein_name": "UMP-CMP kinase 2, mitochondrial", "gene_name": "CMPK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFARRLLRGPLSGPLLGRRGVCAGAMAPPRRFVLELPDCTLAHFALGADAPGDADAPDPRLAALLGPPERSYSLCVPVTPDAGCGARVRAARLHQRLLHQLRRGPFQRCQLLRLLCYCPGGQAGGAQQGFLLRDPLDDPDTRQALLELLGACQEAPRPHLGEFEADPRGQLWQRLWEVQDGRRLQVGCAQVVPVPEPPLHPVVPDLPSSVVFPDREAARAVLEECTSFIPEARAVLDLVDQCPKQIQKGKFQVVAIEGLDATGKTTVTQSVADSLKAVLLKSPPSCIGQWRKIFDDEPTIIRRAFYSLGNYIVASEIAKESAKSPVIVDRYWHSTATYAIATEVSGGLQHLPPAHHPVYQWPEDLLKPDLILLLTVSPEERLQRLQGRGMEKTREEAELEANSVFRQKVEMSYQRMENPGCHVVDASPSREKVLQTVLSLIQNSFSEP", "length": 449 }, "evidence": [ { "id": "A0A5G2RG89", "url": "https://omabrowser.org/oma/group/A0A5G2RG89/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ], "pmid": "" }, { "name": "dTMP kinase activity", "id": "GO:0004798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004798", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ], "pmid": "" }, { "name": "nucleoside diphosphate kinase activity", "id": "GO:0004550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004550", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ], "pmid": "" }, { "name": "UMP kinase activity", "id": "GO:0033862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033862", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ], "pmid": "" }, { "name": "nucleoside monophosphate kinase activity", "id": "GO:0050145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050145", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "dTDP biosynthetic process", "id": "GO:0006233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006233", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ], "pmid": "" }, { "name": "dUDP biosynthetic process", "id": "GO:0006227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006227", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ], "pmid": "" }, { "name": "dTTP biosynthetic process", "id": "GO:0006235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006235", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ], "pmid": "" }, { "name": "pyrimidine nucleotide biosynthetic process", "id": "GO:0006221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006221", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11600", "name": "", "equation": "CMP + ATP = CDP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "11600", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11600" } ] }, { "id": "18113", "name": "", "equation": "a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "18113", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18113" } ] }, { "id": "25094", "name": "", "equation": "dCMP + ATP = dCDP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "25094", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25094" } ] }, { "id": "44640", "name": "", "equation": "a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "44640", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44640" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RG89-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 449, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RG89-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RG89" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RG89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG89" }, { "id": "PF02223", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02223" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thymidylate kinase-like", "eco_id": "ECO_0000259", "start_pos": 257, "end_pos": 436, "start_aa": "Ile", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "uniprot_ac": "A0A5G2RGH3", "uniprot_id": "A0A5G2RGH3_PIG", "mass": { "chemical_mass": 35948.0, "monoisotopic_mass": 35948.0 }, "refseq": { "ac": "XP_003124379", "name": "olfactory receptor 2AE1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124379" }, "gene_names": [ { "name": "LOC100524855", "type": "recommended", "evidence": [ { "id": "A0A5G2RGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3" } ] }, { "name": "LOC100524855", "type": "synonym", "evidence": [ { "id": "XP_003124379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124379" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2AE1-like", "type": "synonym", "evidence": [ { "id": "XP_003124379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124379" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100524855", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3", "locus": {} } ], "crossref": [ { "id": "A0A5G2RGH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524855", "url": "https://www.ncbi.nlm.nih.gov/gene/100524855", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524855", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524855", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RGH3", "url": "https://www.orthodb.org/?gene=A0A5G2RGH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003124379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124379", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RGH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320, "header": "tr|A0A5G2RGH3-1|A0A5G2RGH3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524855 PE=3 SV=1 CANONICAL=A0A5G2RGH3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RGH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3/entry#A0A5G2RGH3-1", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320, "header": "tr|A0A5G2RGH3-1|A0A5G2RGH3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524855 PE=3 SV=1 CANONICAL=A0A5G2RGH3-1" }, "locus": { "chromosome": "3", "start_pos": 7769257, "end_pos": 7768298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071980.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071980.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070314.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070314.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524855", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524855", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "A0A5G2RGH3", "url": "https://omabrowser.org/oma/group/A0A5G2RGH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RGH3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RGH3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGH3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGH3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RGL8-1", "uniprot_ac": "A0A5G2RGL8", "uniprot_id": "A0A5G2RGL8_PIG", "mass": { "chemical_mass": 200474.0, "monoisotopic_mass": 200474.0 }, "refseq": {}, "gene_names": [ { "name": "SETD1B", "type": "recommended", "evidence": [ { "id": "A0A5G2RGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" } ] } ], "protein_names": [ { "name": "[histone H3]-lysine(4) N-methyltransferase", "type": "recommended", "evidence": [ { "id": "A0A5G2RGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.364", "type": "synonym", "evidence": [ { "id": "A0A5G2RGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SETD1B", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8", "locus": { "chromosome": "14", "start_pos": 30862158, "end_pos": 30885260, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000051618", "url": "https://www.ensembl.org/id/ENSSSCG00000051618" } ] } } ], "crossref": [ { "id": "A0A5G2RGL8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000051618", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000051618", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12549", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12549", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19169", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19169", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003616", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003616", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45814", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45814", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45814:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45814:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3214841", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214841", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8936459", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8936459", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9772755", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9772755", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "60264", "url": "https://www.rhea-db.org/rhea/60264", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60268", "url": "https://www.rhea-db.org/rhea/60268", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60272", "url": "https://www.rhea-db.org/rhea/60272", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RGL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENSHPPHHHHQQPPPQPGPSGERRNHHWRSYKLMIDPALKKGHHKLYRYDGQHFSLAVSSRNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLRDMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKEAVQHLHSTSVMGNIIHVELDTKGETRMRFYELLVTGRYTPQTLPVGELDAVSPIVNETLQLSDALKRLKDGGLSTGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSSRQPTPSYLFSQDPTATFKARRHESKFTDAYNRRHEHHYVHNSSSVPAVAGATATFRGSVDLPFGAVGGSGGSGGPPFKAQPQDSATFAHTPPPTQATPTPGVAFKSAFSPYQTPVPPFPPPPEEPAATTPFGARDSGEFRRAPAPPPPPPTEPLTKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLPFLREQDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDDELDLGLGPRPPPEPGPPDPTGLLGQTTEVALDLAGDRTPTSEKMDEVPPCLSISVWDCSLCAGPDPATASTPWLPTTAPTPTTASTPTWLPHAPTSSAPTAPPPPAHPAVTVPPPPLPAPPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQMLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNTGPGRGQPWPPLPKFDPSVPPPGYVPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKASLTPVKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLPSFKVKRKEPPDTASSGDQKRLRPSTSVDEEDEESERERDRDMADAPCELPKRDPKAVGVRRRPARPLELDSGGEEDEKESLSVSSSSSVSSSSGSSTTSPSSSASDKEEREKGPTCVPCPEETVSITTSKPGAESSSESSESSDFESSSESSSSSSEDEEELTAGEEDEEEEEDEDEEEEEAAADESMAPAAPDEDFEEVMAMGAAAVGPEEEVDIEAEGEAPEERAPMLEEPSLPVGVEDLAGCKEPPEEPGLNEQVAGLPSPEPAAGEMEARPLPSPELTQEDKLEAEPAPPTLLSLPLQPPLPPPRLPRPPSPPPEPETTDLPHPAVPLEPPHEDQPPRTPSLCGSLAKSQSAEAVPATPSGEPLPLGGGSSLPLSSPQLPGSPFSYPSPSPGLSSGGLPRTPGRDFSFTPTFPEPGGPLLLPVCPLPAGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPVPVLRAQTRAPTQLPPLLPAPLAPCPPPIKRKPGRPRRSPPAVLSLDGPLVRPPGGATLGRDLLLLPGQPQTPVFPSTHDPRTVTLDFRNPPPPPPPPPVEPTKLPFKELENQWPSEAILSGPRGRDEVTQEFMDLHKVRGPWRRPPKKRHEDLVASVSPELSPPQPLFRPRTEFEEMTILYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHPYILPGGAQRHKVTCPKSHSYNIAEQPRPLTCPLAALPLQGMSIPAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIEDVKIPCLCGSENCRGTLN", "length": 1851, "header": "tr|A0A5G2RGL8-1|A0A5G2RGL8_PIG Isoform 1 of [histone H3]-lysine(4) N-methyltransferase OS=Sus scrofa OX=9823 GN=SETD1B PE=4 SV=2 CANONICAL=A0A5G2RGL8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RGL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8/entry#A0A5G2RGL8-1", "sequence": { "sequence": "MENSHPPHHHHQQPPPQPGPSGERRNHHWRSYKLMIDPALKKGHHKLYRYDGQHFSLAVSSRNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLRDMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKEAVQHLHSTSVMGNIIHVELDTKGETRMRFYELLVTGRYTPQTLPVGELDAVSPIVNETLQLSDALKRLKDGGLSTGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSSRQPTPSYLFSQDPTATFKARRHESKFTDAYNRRHEHHYVHNSSSVPAVAGATATFRGSVDLPFGAVGGSGGSGGPPFKAQPQDSATFAHTPPPTQATPTPGVAFKSAFSPYQTPVPPFPPPPEEPAATTPFGARDSGEFRRAPAPPPPPPTEPLTKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLPFLREQDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDDELDLGLGPRPPPEPGPPDPTGLLGQTTEVALDLAGDRTPTSEKMDEVPPCLSISVWDCSLCAGPDPATASTPWLPTTAPTPTTASTPTWLPHAPTSSAPTAPPPPAHPAVTVPPPPLPAPPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQMLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNTGPGRGQPWPPLPKFDPSVPPPGYVPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKASLTPVKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLPSFKVKRKEPPDTASSGDQKRLRPSTSVDEEDEESERERDRDMADAPCELPKRDPKAVGVRRRPARPLELDSGGEEDEKESLSVSSSSSVSSSSGSSTTSPSSSASDKEEREKGPTCVPCPEETVSITTSKPGAESSSESSESSDFESSSESSSSSSEDEEELTAGEEDEEEEEDEDEEEEEAAADESMAPAAPDEDFEEVMAMGAAAVGPEEEVDIEAEGEAPEERAPMLEEPSLPVGVEDLAGCKEPPEEPGLNEQVAGLPSPEPAAGEMEARPLPSPELTQEDKLEAEPAPPTLLSLPLQPPLPPPRLPRPPSPPPEPETTDLPHPAVPLEPPHEDQPPRTPSLCGSLAKSQSAEAVPATPSGEPLPLGGGSSLPLSSPQLPGSPFSYPSPSPGLSSGGLPRTPGRDFSFTPTFPEPGGPLLLPVCPLPAGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPVPVLRAQTRAPTQLPPLLPAPLAPCPPPIKRKPGRPRRSPPAVLSLDGPLVRPPGGATLGRDLLLLPGQPQTPVFPSTHDPRTVTLDFRNPPPPPPPPPVEPTKLPFKELENQWPSEAILSGPRGRDEVTQEFMDLHKVRGPWRRPPKKRHEDLVASVSPELSPPQPLFRPRTEFEEMTILYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHPYILPGGAQRHKVTCPKSHSYNIAEQPRPLTCPLAALPLQGMSIPAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIEDVKIPCLCGSENCRGTLN", "length": 1851, "header": "tr|A0A5G2RGL8-1|A0A5G2RGL8_PIG Isoform 1 of [histone H3]-lysine(4) N-methyltransferase OS=Sus scrofa OX=9823 GN=SETD1B PE=4 SV=2 CANONICAL=A0A5G2RGL8-1" }, "locus": { "chromosome": "14", "start_pos": 30885260, "end_pos": 30864611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067788.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067788.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074163.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074163.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1297, "start_aa": "Thr", "end_pos": 1297, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1297", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 296, "start_aa": "Thr", "end_pos": 296, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr296", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 386, "start_aa": "Thr", "end_pos": 386, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr386", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 391, "start_aa": "Thr", "end_pos": 391, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr391", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 443, "start_aa": "Thr", "end_pos": 443, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr443", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 561, "start_aa": "Thr", "end_pos": 561, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr561", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 578, "start_aa": "Thr", "end_pos": 578, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr578", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 667, "start_aa": "Thr", "end_pos": 667, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr667", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 669, "start_aa": "Thr", "end_pos": 669, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr669", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 698, "start_aa": "Thr", "end_pos": 698, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr698", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3214841", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214841", "resource": "Reactome", "description": "PKMTs methylate histone lysines" }, { "id": "R-SSC-8936459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8936459", "resource": "Reactome", "description": "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" }, { "id": "R-SSC-9772755", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9772755", "resource": "Reactome", "description": "Formation of WDR5-containing histone-modifying complexes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" } ], "pmid": "" }, { "name": "histone H3K4 methyltransferase activity", "id": "GO:0042800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" } ], "pmid": "" }, { "name": "histone H3K4 monomethyltransferase activity", "id": "GO:0140945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140945", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" } ], "pmid": "" }, { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1617, "end_pos": 1619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1790, "end_pos": 1792, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60264", "name": "", "equation": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60264", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60264" } ] }, { "id": "60268", "name": "", "equation": "N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60268", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60268" } ] }, { "id": "60272", "name": "", "equation": "N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60272", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60272" } ] }, { "id": "R-SSC-4827382", "name": "SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-4827382", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4827382" } ] }, { "id": "R-SSC-5159245", "name": "SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5159245", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5159245" } ] }, { "id": "R-SSC-5244692", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5244692", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5244692" } ] }, { "id": "R-SSC-5637686", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5637686", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5637686" } ] }, { "id": "R-SSC-8936481", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8936481", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8936481" } ] }, { "id": "R-SSC-8936621", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8936621", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8936621" } ] }, { "id": "R-SSC-8937016", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8937016", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8937016" } ] }, { "id": "R-SSC-8937050", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8937050", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8937050" } ] }, { "id": "R-SSC-9676264", "name": "Formation of the SET1B complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9676264", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9676264" } ] }, { "id": "R-SSC-9821476", "name": "CXXC1 and WDR82 bind SET1B complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9821476", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9821476" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RGL8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1851, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RGL8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGL8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" }, { "id": "PS50868", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50868" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Post-SET", "eco_id": "ECO_0000259", "start_pos": 1835, "end_pos": 1851, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 182, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGL8" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 1712, "end_pos": 1829, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 296, 386, 391, 443, 561, 578, 667, 669, 698, 1297 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1617, "end_pos": 1619 }, { "start_pos": 1790, "end_pos": 1792 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 333, "end_pos": 335 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 10 }, { "field": "total_sites", "count": 10 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 10 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 10 }, { "field": "exact_o_linked_sites", "count": 10 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 10 }, { "field": "total_sites", "count": 10 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 10 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 10 }, { "field": "exact_o_linked_sites", "count": 10 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RGR9-1", "uniprot_ac": "A0A5G2RGR9", "uniprot_id": "A0A5G2RGR9_PIG", "mass": { "chemical_mass": 62256.0, "monoisotopic_mass": 62256.0 }, "refseq": {}, "gene_names": [ { "name": "TAF15", "type": "recommended", "evidence": [ { "id": "A0A5G2RGR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9" } ] } ], "protein_names": [ { "name": "TATA-box binding protein associated factor 15", "type": "synonym", "evidence": [ { "id": "A0A5G2RGR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TAF15", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9", "locus": { "chromosome": "12", "start_pos": 39686884, "end_pos": 39724769, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017707", "url": "https://www.ensembl.org/id/ENSSSCG00000017707" } ] } } ], "crossref": [ { "id": "A0A5G2RGR9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGR9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017707", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017707", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12535", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12535", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23238", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23238", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6804756", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804756", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73776", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73776", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73779", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73779", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-75953", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75953", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-76042", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RGR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S187", "url": "https://www.uniprot.org/uniprotkb/F1S187", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S187-1", "url": "https://www.uniprot.org/uniprotkb/F1S187-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "DSGSYGQSGGEQQSYSSYGNQGNQGYGQAPQGYSGYGQTTDSSYGQNYGGYSSYGQSQSGYSQPYGGYENQKQSSYGQPSYNNQGQQNTESSGGQSGRVPSYDQSDYGQQDSYNQQSGYDHHQGSYDEQSNYNQQHDSYNQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRPDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSGGGGYGGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRSGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGYGGDRSGGGYGGDRGSGSGYGGDRSGGYGGDRSGGGYGGDRSGGYGGDRGGYGGKMGGRNDYRNDQRNRPY", "length": 600, "header": "tr|A0A5G2RGR9-1|A0A5G2RGR9_PIG Isoform 1 of TATA-box binding protein associated factor 15 OS=Sus scrofa OX=9823 GN=TAF15 PE=1 SV=1 CANONICAL=A0A5G2RGR9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RGR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9/entry#A0A5G2RGR9-1", "sequence": { "sequence": "DSGSYGQSGGEQQSYSSYGNQGNQGYGQAPQGYSGYGQTTDSSYGQNYGGYSSYGQSQSGYSQPYGGYENQKQSSYGQPSYNNQGQQNTESSGGQSGRVPSYDQSDYGQQDSYNQQSGYDHHQGSYDEQSNYNQQHDSYNQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRPDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSGGGGYGGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRSGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGYGGDRSGGGYGGDRGSGSGYGGDRSGGYGGDRSGGGYGGDRSGGYGGDRGGYGGKMGGRNDYRNDQRNRPY", "length": 600, "header": "tr|A0A5G2RGR9-1|A0A5G2RGR9_PIG Isoform 1 of TATA-box binding protein associated factor 15 OS=Sus scrofa OX=9823 GN=TAF15 PE=1 SV=1 CANONICAL=A0A5G2RGR9-1" }, "locus": { "chromosome": "12", "start_pos": 39716762, "end_pos": 39687174, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074923.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074923.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070444.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070444.1" } ] } }, { "isoform_ac": "F1S187-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9/entry#F1S187-1", "sequence": { "sequence": "MSDSGSYGQSGGEQQSYSSYGNQGNQGYGQAPQGYSGYGQTTDSSYGQNYGGYSSYGQSQSGYSQPYGGYENQKQSSYGQPSYNNQGQQNTESSGGQSGRVPSYDQSDYGQQDSYNQQSGYDHHQGSYDEQSNYNQQHDSYNQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRPDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSGGGGYGGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRSGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRSGGGYGGDRGSGSGYGGDRSGGYGGDRSGGGYGGDRSGGYGGDRGGYGGKMGGRNDYRNDQRNRPY", "length": 549, "header": "tr|F1S187-1|A0A5G2RGR9_PIG Computationally mapped isoform of TATA-box binding protein associated factor 15 OS=Sus scrofa OX=9823 GN=TAF15 PE=1 SV=4 CANONICAL=A0A5G2RGR9-1" }, "locus": { "chromosome": "12", "start_pos": 39724653, "end_pos": 39687174, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019273.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019273.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018762.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018762.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S187", "url": "https://www.uniprot.org/uniprotkb/F1S187" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-SSC-6804756", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804756", "resource": "Reactome", "description": "Regulation of TP53 Activity through Phosphorylation" }, { "id": "R-SSC-73776", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73776", "resource": "Reactome", "description": "RNA Polymerase II Promoter Escape" }, { "id": "R-SSC-73779", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73779", "resource": "Reactome", "description": "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" }, { "id": "R-SSC-75953", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75953", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation" }, { "id": "R-SSC-76042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76042", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation And Promoter Clearance" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RGR9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 600, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RGR9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGR9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RGR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 317, "start_aa": "Asn", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RGR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGR9" }, { "id": "PS50199", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50199" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RanBP2-type", "eco_id": "ECO_0000259", "start_pos": 351, "end_pos": 382, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 230, "end_pos": 232 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RGT1-1", "uniprot_ac": "A0A5G2RGT1", "uniprot_id": "A0A5G2RGT1_PIG", "mass": { "chemical_mass": 36273.0, "monoisotopic_mass": 36273.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100520547", "type": "recommended", "evidence": [ { "id": "A0A5G2RGT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RGT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100520547", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1", "locus": {} } ], "crossref": [ { "id": "A0A5G2RGT1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NSICHTM", "url": "https://omabrowser.org/oma/group/NSICHTM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RGT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGHVNHTFSNDFILLGLFSSSQTCLIFFSFIVIIFSTAVTENAIMILLIHRESRLHTPMYFLLSHLSFMDILHISNIVPKMITDFLSGNRAISFAGCGFQIFLSLTLSGGECLLLAAMSYDRYVAICHPLRYPILMDDYVSILMAGGSWLIATVNSIVHTVYTLHLPFCGSRAIDHFFCDVSAMLVLSCVDTTHYERGVYVSSIIFLLVPFSLIFASYVQILLTVLQMKSSEAWKKSFSTCFFHMIVVIMYYGPFIFTYMRPKMYHTPGQDKFLAIFYTILTPSFNPIIYSFRNKDVLEALKNMIKSNFLHKNNRKSA", "length": 318, "header": "tr|A0A5G2RGT1-1|A0A5G2RGT1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100520547 PE=3 SV=2 CANONICAL=A0A5G2RGT1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RGT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1/entry#A0A5G2RGT1-1", "sequence": { "sequence": "MGHVNHTFSNDFILLGLFSSSQTCLIFFSFIVIIFSTAVTENAIMILLIHRESRLHTPMYFLLSHLSFMDILHISNIVPKMITDFLSGNRAISFAGCGFQIFLSLTLSGGECLLLAAMSYDRYVAICHPLRYPILMDDYVSILMAGGSWLIATVNSIVHTVYTLHLPFCGSRAIDHFFCDVSAMLVLSCVDTTHYERGVYVSSIIFLLVPFSLIFASYVQILLTVLQMKSSEAWKKSFSTCFFHMIVVIMYYGPFIFTYMRPKMYHTPGQDKFLAIFYTILTPSFNPIIYSFRNKDVLEALKNMIKSNFLHKNNRKSA", "length": 318, "header": "tr|A0A5G2RGT1-1|A0A5G2RGT1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100520547 PE=3 SV=2 CANONICAL=A0A5G2RGT1-1" }, "locus": { "chromosome": "2", "start_pos": 55472602, "end_pos": 55471649, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083869.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083869.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074263.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074263.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q8VGL6-1", "protein_name": "Olfactory receptor", "gene_name": "Or2aj5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEYENYTFNDFILLGLFSSSKTSLTFFSVIFFIFIMAITENALMILLIHRDSRLHTPMYFLLSHLSFMDILHISNIVPKMIADFLSGSRTISFAGCAFQIFLSLTLLGGECLLLAAMSYDRYVAICHPLCYPVLMRDNFSRLLAAGSWLVGILNSIVHTAFVLHFPFCHSRAIDHFFCEVPAMLKLSCIDTTHYEQGVYVSGIIFLMVPFSMISISYVQILLTVFQMHSSGARQKSFSTCLFHMVVVIMYYGPVIFTYMRPRSYHTPGQDKFLAIFYTILTPKLNPIIYSFRNKDVLRALKNIVQSNILNKK", "length": 313 }, "evidence": [ { "id": "A0A5G2RGT1", "url": "https://omabrowser.org/oma/group/A0A5G2RGT1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RGT1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 318, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RGT1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RGT1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RGT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGT1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RH22-1", "uniprot_ac": "A0A5G2RH22", "uniprot_id": "A0A5G2RH22_PIG", "mass": { "chemical_mass": 46852.0, "monoisotopic_mass": 46852.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "L1 transposable element RRM domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RH22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH22/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH22" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH22", "locus": {} } ], "crossref": [ { "id": "A0A5G2RH22", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RH22", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000044995", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000044995", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RH22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RH22-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLRNHSQSNQQENSPKTVNNETDLCSLTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENQIKKLESNIRDLWDNINRANLHIIGIPEGVEKDKGMENIFEEIITGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTRIRLSADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKIFSIKQKLKEYSNTKPMLKEILNRHFSKEDIQMANKHMIKCSTSLIIREMQIKTTTRYHLTPVRMAITNKSTNNKCWRGCGEKGTLLHCWWECQLVQPLWRTVWRYLRNLYIELPYDPAIPLLGIYPD", "length": 398, "header": "tr|A0A5G2RH22-1|A0A5G2RH22_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RH22-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RH22-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH22/entry#A0A5G2RH22-1", "sequence": { "sequence": "MKKLRNHSQSNQQENSPKTVNNETDLCSLTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENQIKKLESNIRDLWDNINRANLHIIGIPEGVEKDKGMENIFEEIITGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTRIRLSADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKIFSIKQKLKEYSNTKPMLKEILNRHFSKEDIQMANKHMIKCSTSLIIREMQIKTTTRYHLTPVRMAITNKSTNNKCWRGCGEKGTLLHCWWECQLVQPLWRTVWRYLRNLYIELPYDPAIPLLGIYPD", "length": 398, "header": "tr|A0A5G2RH22-1|A0A5G2RH22_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RH22-1" }, "locus": { "chromosome": "13", "start_pos": 150791950, "end_pos": 150790757, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079339.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079339.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074419.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074419.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH22" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH22" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH22" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH22", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH22" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RH22-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 398, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RH22-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RH22" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RH22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH22" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 227, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RH22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH22" }, { "id": "PF17490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element dsRBD-like", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 293, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 22, "end_pos": 24 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2R8J7-1", "uniprot_ac": "A0A5G2R8J7", "uniprot_id": "A0A5G2R8J7_PIG", "mass": { "chemical_mass": 40041.0, "monoisotopic_mass": 40041.0 }, "refseq": {}, "gene_names": [ { "name": "SEPTIN3", "type": "recommended", "evidence": [ { "id": "A0A5G2R8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" } ] } ], "protein_names": [ { "name": "Neuronal-specific septin-3", "type": "recommended", "evidence": [ { "id": "A0A5G2R8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Filament-forming cytoskeletal GTPase. May play a role in cytokinesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYB7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYB7#function" }, { "database": "UniProtKB", "id": "ARBA00046092", "url": "https://www.uniprot.org/uniprotkb/ARBA00046092#function" }, { "database": "UniProtKB", "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7#function" }, { "database": "UniProtKB", "id": "A0A287BHJ1", "url": "https://www.uniprot.org/uniprotkb/A0A287BHJ1#function" }, { "database": "UniProtKB", "id": "A0A8W4F9F5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9F5#function" }, { "database": "UniProtKB", "id": "A0A8W4FJ04", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJ04#function" }, { "database": "UniProtKB", "id": "A0A287BRG9", "url": "https://www.uniprot.org/uniprotkb/A0A287BRG9#function" }, { "database": "UniProtKB", "id": "A0A5G2QCJ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCJ0#function" }, { "database": "UniProtKB", "id": "A0A5G2QPP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPP7#function" }, { "database": "UniProtKB", "id": "F1SJQ3", "url": "https://www.uniprot.org/uniprotkb/F1SJQ3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SEPTIN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7", "locus": { "chromosome": "5", "start_pos": 6623265, "end_pos": 6660702, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000040", "url": "https://www.ensembl.org/id/ENSSSCG00000000040" } ] } } ], "crossref": [ { "id": "A0A5G2R8J7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8J7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000040", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000040", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01850", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01850", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR008114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR18884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287BHJ1", "url": "https://www.uniprot.org/uniprotkb/A0A287BHJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BHJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BHJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BRG9", "url": "https://www.uniprot.org/uniprotkb/A0A287BRG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BRG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BRG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QCJ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QCJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYB7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9F5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9F5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJ04", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJ04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJ04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJ04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJQ3", "url": "https://www.uniprot.org/uniprotkb/F1SJQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1SJQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKGLPEARTDTAMSELVPEPRPKPAVPMKPVSINSSLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPVSVDTEESHDSNP", "length": 350, "header": "tr|A0A5G2R8J7-1|A0A5G2R8J7_PIG Isoform 1 of Neuronal-specific septin-3 OS=Sus scrofa OX=9823 GN=SEPTIN3 PE=1 SV=1 CANONICAL=A0A5G2R8J7-1" }, "isoforms": [ { "isoform_ac": "A0A287BHJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7/entry#A0A287BHJ1-1", "sequence": { "sequence": "MRDGYWVPSEVPSRPQVCMMLGPEGNRVALCALCFPAAHPSLLGFAGLPEARTDTAMSELVPEPRPKPAVPMKPVSINSSLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPACLIFVEHLVYSVHVHTCVCVCVCVYM", "length": 407, "header": "tr|A0A287BHJ1-1|A0A287BHJ1_PIG Computationally mapped isoform of Neuronal-specific septin-3 OS=Sus scrofa OX=9823 GN=SEPTIN3 PE=1 SV=2 CANONICAL=A0A5G2R8J7-1" }, "locus": { "chromosome": "5", "start_pos": 6649634, "end_pos": 6635033, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049671.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049671.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056057.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056057.2" } ] } }, { "isoform_ac": "A0A287BRG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7/entry#A0A287BRG9-1", "sequence": { "sequence": "MESSRQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPGEGLLGTVLPPVPAIPCPTAE", "length": 295, "header": "tr|A0A287BRG9-1|A0A287BRG9_PIG Computationally mapped isoform of Neuronal-specific septin-3 OS=Sus scrofa OX=9823 GN=SEPTIN3 PE=1 SV=3 CANONICAL=A0A5G2R8J7-1" }, "locus": { "chromosome": "5", "start_pos": 6645539, "end_pos": 6633029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040807.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040807.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059038.3", "url": "https://www.ensembl.org/id/ENSSSCP00000059038.3" } ] } }, { "isoform_ac": "A0A5G2QCJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7/entry#A0A5G2QCJ0-1", "sequence": { "sequence": "MDHDLEMQPHGAPGPGTSFSRGHLLGRPARPSKLPGGVSPLIPVLRKTIHLDACPQSHIPQAPGRLGLGARTRSVPLQDTGKSLVPRKLSSVSLTLRQHSHAWPLGPLPSHWEELSTSGTHGGGRLPTPGSPSVTRAPGGRVHSEDPGNPGLAKPSKMPTVEKPLVSSYLTLPFQARLAQSPPGPAGPGAGGQRHPVPATAHVPTRASPGRGKPRARGIPRPRLQLQRATPTTGSAMAMDLATPDPTRPGTARHLATAANRPGLAVNLATPNTSRLDMGTEFPDLDPKLGTATDLASAGTTKPGMVMDLVTSDPEKVSKAIPTAGTAKPDTTTGGPAMDLAVPDPVKLGTARPDRAMVLSRANTANLDITTNSLAMHTTSRLGRAMGSVVPVTPDPATGEIALDCVINLTTSDIAIYPSMLSRSPDPALDHVTADAATDLATEITMLDLARESRGLPEARTDTAMSELVPEPRPKPAVPMKPVSINSSLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPGEGLLGTVLPPVPAIPCPTAE", "length": 809, "header": "tr|A0A5G2QCJ0-1|A0A5G2QCJ0_PIG Computationally mapped isoform of Neuronal-specific septin-3 OS=Sus scrofa OX=9823 GN=SEPTIN3 PE=1 SV=1 CANONICAL=A0A5G2R8J7-1" }, "locus": { "chromosome": "5", "start_pos": 6658530, "end_pos": 6633029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082407.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082407.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059749.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059749.1" } ] } }, { "isoform_ac": "A0A5G2QPP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7/entry#A0A5G2QPP7-1", "sequence": { "sequence": "MSKGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPGEGLLGTVLPPVPAIPCPTAE", "length": 294, "header": "tr|A0A5G2QPP7-1|A0A5G2R8J7_PIG Computationally mapped isoform of Neuronal-specific septin-3 OS=Sus scrofa OX=9823 GN=SEPTIN3 PE=1 SV=1 CANONICAL=A0A5G2R8J7-1" }, "locus": { "chromosome": "5", "start_pos": 6653901, "end_pos": 6633029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087040.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087040.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066680.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066680.1" } ] } }, { "isoform_ac": "A0A5G2QYB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7/entry#A0A5G2QYB7-1", "sequence": { "sequence": "MDHDLEMQPHGAPGPGTSFSRGHLLGRPARPSKLPGGVSPLIPVLRKTIHLDACPQSHIPQAPGRLGLGARTRSVPLQDTGKSLVPRKLSSVSLTLRQHSHAWPLGPLPSHWEELSTSGTHGGGRLPTPGSPSVTRAPGGRVHSEDPGNPGLAKPSKMPTVEKPLVSSYLTLPFQARLAQSPPGPAGPGAGGQRHPVPATAHVPTRASPGRGKPRARGIPRPRLQLQRATPTTGSAMAMDLATPDPTRPGTARHLATAANRPGLAVNLATPNTSRLDMGTEFPDLDPKLGTATDLASAGTTKPGMVMDLVTSDPEKVSKAIPTAGTAKPDTTTGGPAMDLAVPDPVKLGTARPDRAMVLSRANTANLDITTNSLAMHTTSRLGRAMGSVVPVTPDPATGEIALDCVINLTTSDIAIYPSMLSRSPDPALDHVTADAATDLATEITMLDLARESRGLPEARTDTAMSELVPEPRPKPAVPMKPVSINSSLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIREKASWALSFHLYQPSPAPLLNEGHSKRRSSLHSSQRIAAGPRPF", "length": 801, "header": "tr|A0A5G2QYB7-1|A0A5G2R8J7_PIG Computationally mapped isoform of Neuronal-specific septin-3 OS=Sus scrofa OX=9823 GN=SEPTIN3 PE=1 SV=1 CANONICAL=A0A5G2R8J7-1" }, "locus": { "chromosome": "5", "start_pos": 6658530, "end_pos": 6632959, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076217.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076217.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063209.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063209.1" } ] } }, { "isoform_ac": "A0A5G2R8J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7/entry#A0A5G2R8J7-1", "sequence": { "sequence": "MSKGLPEARTDTAMSELVPEPRPKPAVPMKPVSINSSLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPVSVDTEESHDSNP", "length": 350, "header": "tr|A0A5G2R8J7-1|A0A5G2R8J7_PIG Isoform 1 of Neuronal-specific septin-3 OS=Sus scrofa OX=9823 GN=SEPTIN3 PE=1 SV=1 CANONICAL=A0A5G2R8J7-1" }, "locus": { "chromosome": "5", "start_pos": 6653901, "end_pos": 6635244, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069730.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069730.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070447.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070447.1" } ] } }, { "isoform_ac": "A0A8W4F9F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7/entry#A0A8W4F9F5-1", "sequence": { "sequence": "ASKRQRLPEARTDTAMSELVPEPRPKPAVPMKPVSINSSLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPVSVDTEESHDSNP", "length": 352, "header": "tr|A0A8W4F9F5-1|A0A5G2R8J7_PIG Computationally mapped isoform of Neuronal-specific septin-3 OS=Sus scrofa OX=9823 GN=SEPTIN3 PE=1 SV=1 CANONICAL=A0A5G2R8J7-1" }, "locus": { "chromosome": "5", "start_pos": 6650100, "end_pos": 6635244, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104732.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104732.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074921.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074921.1" } ] } }, { "isoform_ac": "A0A8W4FJ04-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7/entry#A0A8W4FJ04-1", "sequence": { "sequence": "MDHDLEMQPHGAPGPGTSFSRGHLLGRPARPSKLPGGVSPLIPVLRKTIHLDACPQSHIPQAPGRLGLGARTRSVPLQDTGKSLVPRKLSSVSLTLRQHSHAWPLGPLPSHWEELSTSGTHGGGRLPTPGSPSVTRAPGGRVHSEDPGNPGLAKPSKMPTVEKPLVSSYLTLPFQARLAQSPPGPAGPGAGGQRHPVPATAHVPTRASPGRGKPRARGIPRPRLQLQRATPTTGSAMAMDLATPDPTRPGTARHLATAANRPGLAVNLATPNTSRLDMGTEFPDLDPKLGTATDLASAGTTKPGMVMDLVTSDPEKVSKAIPTAGTAKPDTTTGGPAMDLAVPDPVKLGTARPDRAMVLSRANTANLDITTNSLAMHTTSRLGRAMGSVVPVTPDPATGEIALDCVINLTTSDIAIYPSMLSRSPDPALDHVTADAATDLATEITMLDLARESRGLPEARTDTAMSELVPEPRPKPAVPMKPVSINSSLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEGNSVEKASWALSFHLYQPSPAPLLNEGHSKRRSSLHSSQRIAAGPRPF", "length": 787, "header": "tr|A0A8W4FJ04-1|A0A5G2R8J7_PIG Computationally mapped isoform of Neuronal-specific septin-3 OS=Sus scrofa OX=9823 GN=SEPTIN3 PE=1 SV=1 CANONICAL=A0A5G2R8J7-1" }, "locus": { "chromosome": "5", "start_pos": 6658530, "end_pos": 6632959, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093163.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093163.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079214.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079214.1" } ] } }, { "isoform_ac": "F1SJQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7/entry#F1SJQ3-1", "sequence": { "sequence": "FAGLPEARTDTAMSELVPEPRPKPAVPMKPVSINSSLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPCFEAVSGCGSLLPTAARRI", "length": 355, "header": "tr|F1SJQ3-1|A0A5G2R8J7_PIG Computationally mapped isoform of Neuronal-specific septin-3 OS=Sus scrofa OX=9823 GN=SEPTIN3 PE=1 SV=4 CANONICAL=A0A5G2R8J7-1" }, "locus": { "chromosome": "5", "start_pos": 6649502, "end_pos": 6623317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000042.5", "url": "https://www.ensembl.org/id/ENSSSCT00000000042.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000042.4", "url": "https://www.ensembl.org/id/ENSSSCP00000000042.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPP7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" } ], "pmid": "" }, { "name": "septin ring", "id": "GO:0005940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005940", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" } ], "pmid": "" }, { "name": "septin complex", "id": "GO:0031105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031105", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" } ], "pmid": "" }, { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8J7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2R8J7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 350, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2R8J7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2R8J7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2R8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8J7" }, { "id": "PS51719", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51719" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Septin-type G", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 331, "start_aa": "Thr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 35, "end_pos": 37 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T6D6-1", "uniprot_ac": "A0A4X1T6D6", "uniprot_id": "A0A4X1T6D6_PIG", "mass": { "chemical_mass": 37606.0, "monoisotopic_mass": 37606.0 }, "refseq": {}, "gene_names": [ { "name": "RPL10", "type": "recommended", "evidence": [ { "id": "A0A4X1T6D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6" } ] } ], "protein_names": [ { "name": "Ribosomal protein L10", "type": "synonym", "evidence": [ { "id": "A0A4X1T6D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6D6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPL10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6", "locus": { "chromosome": "X", "start_pos": 124929791, "end_pos": 124926772, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000035997", "url": "https://www.ensembl.org/id/ENSSSCG00000035997" } ] } } ], "crossref": [ { "id": "A0A4X1T6D6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T6D6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01433", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01433", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11726", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11726", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00252", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00252", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1T3W2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T3W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3W2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T5U8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T5U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T6D6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T6D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1F496", "url": "https://www.uniprot.org/uniprotkb/A0A8D1F496", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1F496-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1F496-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A900R0B1", "url": "https://www.uniprot.org/uniprotkb/A0A900R0B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A900R0B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A900R0B1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFIVTAKPRARILRPRWPTGSWLLEPMWRSPIRQSAAHGRVLSRLPALRMCAGTPVHMRRAPPRLWSGSLTERLLARPQTLWFLPVKIDRLYKGCAGVGAPLFLRRATEDLGVAMGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFENMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS", "length": 329, "header": "tr|A0A4X1T6D6-1|A0A4X1T6D6_PIG Isoform 1 of Ribosomal protein L10 OS=Sus scrofa OX=9823 GN=RPL10 PE=3 SV=1 CANONICAL=A0A4X1T6D6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T3W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6/entry#A0A4X1T3W2-1", "sequence": { "sequence": "MGRRPARCYRYCKNKPYPKSRFCRGVPALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFENMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS", "length": 178, "header": "tr|A0A4X1T3W2-1|A0A4X1T3W2_PIG Computationally mapped isoform of Ribosomal protein L10 OS=Sus scrofa OX=9823 GN=RPL10 PE=3 SV=1 CANONICAL=A0A4X1T6D6-1" }, "locus": { "chromosome": "X", "start_pos": 124929730, "end_pos": 124927395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068711.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068711.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074121.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074121.1" } ] } }, { "isoform_ac": "A0A4X1T5U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6/entry#A0A4X1T5U8-1", "sequence": { "sequence": "MAEAPLGCVPAEPWNRTGEAQRARPKPHDARGQTLWFLPVKIDRLYKGCAGVGAPLFLRRATEDLGVAMGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFENMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS", "length": 282, "header": "tr|A0A4X1T5U8-1|A0A4X1T5U8_PIG Computationally mapped isoform of Ribosomal protein L10 OS=Sus scrofa OX=9823 GN=RPL10 PE=3 SV=1 CANONICAL=A0A4X1T6D6-1" }, "locus": { "chromosome": "X", "start_pos": 124929730, "end_pos": 124926790, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083966.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083966.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068012.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068012.1" } ] } }, { "isoform_ac": "A0A4X1T6D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6/entry#A0A4X1T6D6-1", "sequence": { "sequence": "MSFIVTAKPRARILRPRWPTGSWLLEPMWRSPIRQSAAHGRVLSRLPALRMCAGTPVHMRRAPPRLWSGSLTERLLARPQTLWFLPVKIDRLYKGCAGVGAPLFLRRATEDLGVAMGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFENMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS", "length": 329, "header": "tr|A0A4X1T6D6-1|A0A4X1T6D6_PIG Isoform 1 of Ribosomal protein L10 OS=Sus scrofa OX=9823 GN=RPL10 PE=3 SV=1 CANONICAL=A0A4X1T6D6-1" }, "locus": { "chromosome": "X", "start_pos": 124929730, "end_pos": 124926945, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041617.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041617.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035267.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035267.2" } ] } }, { "isoform_ac": "A0A8D1F496-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6/entry#A0A8D1F496-1", "sequence": { "sequence": "MGRRPARWGRREPFTWLREGLIATCPNVFSYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFENMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS", "length": 236, "header": "tr|A0A8D1F496-1|A0A4X1T6D6_PIG Computationally mapped isoform of Ribosomal protein L10 OS=Sus scrofa OX=9823 GN=RPL10 PE=3 SV=1 CANONICAL=A0A4X1T6D6-1" }, "locus": { "chromosome": "X", "start_pos": 124929730, "end_pos": 124927395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043358.2", "url": "https://www.ensembl.org/id/ENSSSCT00000043358.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042364.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042364.2" } ] } }, { "isoform_ac": "A0A900R0B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6/entry#A0A900R0B1-1", "sequence": { "sequence": "MGWGLPFAGRREPFTWLREGLIATCPNVFSYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFENMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS", "length": 236, "header": "tr|A0A900R0B1-1|A0A4X1T6D6_PIG Computationally mapped isoform of Ribosomal protein L10 OS=Sus scrofa OX=9823 GN=RPL10 PE=3 SV=1 CANONICAL=A0A4X1T6D6-1" }, "locus": { "chromosome": "X", "start_pos": 124929730, "end_pos": 124927492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089173.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089173.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060715.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060715.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1F496", "url": "https://www.uniprot.org/uniprotkb/A0A8D1F496" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6D6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6D6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "large ribosomal subunit", "id": "GO:0015934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015934", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6D6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6D6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6D6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1UKA4-1", "uniprot_ac": "A0A5K1UKA4", "uniprot_id": "A0A5K1UKA4_PIG", "mass": { "chemical_mass": 37536.0, "monoisotopic_mass": 37536.0 }, "refseq": { "ac": "XP_013836270", "name": "dual specificity mitogen-activated protein kinase kinase 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836270" }, "gene_names": [ { "name": "MAP2K6", "type": "recommended", "evidence": [ { "id": "A0A5K1UKA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ] }, { "name": "MAP2K6", "type": "synonym", "evidence": [ { "id": "XP_013836270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836270" } ] } ], "protein_names": [ { "name": "mitogen-activated protein kinase kinase", "type": "recommended", "evidence": [ { "id": "A0A5K1UKA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4/entry#names_and_taxonomy" } ] }, { "name": "2.7.12.2", "type": "synonym", "evidence": [ { "id": "A0A5K1UKA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4/entry#names_and_taxonomy" } ] }, { "name": "dual specificity mitogen-activated protein kinase kinase 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013836270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836270" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MAP2K6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4", "locus": { "chromosome": "12", "start_pos": 10894966, "end_pos": 11018641, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017254", "url": "https://www.ensembl.org/id/ENSSSCG00000017254" } ] } } ], "crossref": [ { "id": "A0A5K1UKA4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1UKA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017254", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017254", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06617", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06617", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100625946", "url": "https://www.ncbi.nlm.nih.gov/gene/100625946", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100625946", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625946", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FPYNTWG", "url": "https://omabrowser.org/oma/group/FPYNTWG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5K1UKA4", "url": "https://www.orthodb.org/?gene=A0A5K1UKA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48013", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48013", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48013:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48013:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-168638", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-168638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2559580", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559580", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-450302", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450302", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6811555", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9020702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9020702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013836270", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836270", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UKA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F793", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F793", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F793-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F793-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RV28", "url": "https://www.uniprot.org/uniprotkb/F1RV28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RV28-1", "url": "https://www.uniprot.org/uniprotkb/F1RV28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKATDVASFVKSILGD", "length": 334, "header": "tr|A0A5K1UKA4-1|A0A5K1UKA4_PIG Isoform 1 of mitogen-activated protein kinase kinase OS=Sus scrofa OX=9823 GN=MAP2K6 PE=1 SV=1 CANONICAL=A0A5K1UKA4-1" }, "isoforms": [ { "isoform_ac": "A0A5K1UKA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4/entry#A0A5K1UKA4-1", "sequence": { "sequence": "MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKATDVASFVKSILGD", "length": 334, "header": "tr|A0A5K1UKA4-1|A0A5K1UKA4_PIG Isoform 1 of mitogen-activated protein kinase kinase OS=Sus scrofa OX=9823 GN=MAP2K6 PE=1 SV=1 CANONICAL=A0A5K1UKA4-1" }, "locus": { "chromosome": "12", "start_pos": 11018341, "end_pos": 10902422, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035633.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035633.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030562.2", "url": "https://www.ensembl.org/id/ENSSSCP00000030562.2" } ] } }, { "isoform_ac": "A0A8W4F793-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4/entry#A0A8W4F793-1", "sequence": { "sequence": "ISQSILFNSSTKKRNPGLKIPKENFEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKATDVASFVKSILGD", "length": 313, "header": "tr|A0A8W4F793-1|A0A5K1UKA4_PIG Computationally mapped isoform of mitogen-activated protein kinase kinase OS=Sus scrofa OX=9823 GN=MAP2K6 PE=1 SV=1 CANONICAL=A0A5K1UKA4-1" }, "locus": { "chromosome": "12", "start_pos": 10939963, "end_pos": 10902422, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103830.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103830.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075079.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075079.1" } ] } }, { "isoform_ac": "F1RV28-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4/entry#F1RV28-1", "sequence": { "sequence": "ISQSILFNSSTKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKATDVASFVKSILGD", "length": 339, "header": "tr|F1RV28-1|A0A5K1UKA4_PIG Computationally mapped isoform of mitogen-activated protein kinase kinase OS=Sus scrofa OX=9823 GN=MAP2K6 PE=1 SV=2 CANONICAL=A0A5K1UKA4-1" }, "locus": { "chromosome": "12", "start_pos": 10939963, "end_pos": 10902422, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018783.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018783.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018281.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018281.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RV28", "url": "https://www.uniprot.org/uniprotkb/F1RV28" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100625946", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625946", "resource": "KEGG Pathway" }, { "id": "R-SSC-168638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-168638", "resource": "Reactome", "description": "NOD1/2 Signaling Pathway" }, { "id": "R-SSC-2559580", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559580", "resource": "Reactome", "description": "Oxidative Stress Induced Senescence" }, { "id": "R-SSC-450302", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450302", "resource": "Reactome", "description": "activated TAK1 mediates p38 MAPK activation" }, { "id": "R-SSC-6811555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811555", "resource": "Reactome", "description": "PI5P Regulates TP53 Acetylation" }, { "id": "R-SSC-9020702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9020702", "resource": "Reactome", "description": "Interleukin-1 signaling" }, { "id": "R-SSC-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M3C5-1", "protein_name": "mitogen-activated protein kinase kinase", "gene_name": "Map2k6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHRDLKGKKRNPGLKIPREAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSKERPTYPELMQHPFFTVHEAKAADVASFVKLILGD", "length": 335 }, "evidence": [ { "id": "A0A5K1UKA4", "url": "https://omabrowser.org/oma/group/A0A5K1UKA4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O62602-1", "protein_name": "mitogen-activated protein kinase kinase", "gene_name": "lic", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKRHRLTPFTIAKEPEAAIVPPRNLDSRATIQIGDRTFDIDADSLEKICDLGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDISMRSSDCPYTVHFYGAMYREGDVWICMEVMSTSLDKFYPKVFLHDLRMEESVLGKIAMSVVSALHYLHAQLKVIHRDVKPSNILINRAGQVKICDFGISGYLVDSIAKTIDAGCKPYMAPERIDPQGNPAQYDIRSDVWSLGIGMIEMATGRYPYDNWRTPFEQLRQVVEDSPPRLPEGTFSPEFEDFIAVCLQKEYMARPNYEQLLKHSFIVEHLQRNTDISEFVARILDLPDAQPAQ", "length": 334 }, "evidence": [ { "id": "A0A5K1UKA4", "url": "https://omabrowser.org/oma/group/A0A5K1UKA4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P52564-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 6", "gene_name": "MAP2K6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD", "length": 334 }, "evidence": [ { "id": "A0A5K1UKA4", "url": "https://omabrowser.org/oma/group/A0A5K1UKA4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70236-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 6", "gene_name": "Map2k6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSKERPTYPELMQHPFFTVHESKAADVASFVKLILGD", "length": 334 }, "evidence": [ { "id": "A0A5K1UKA4", "url": "https://omabrowser.org/oma/group/A0A5K1UKA4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5E9X2-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 6", "gene_name": "MAP2K6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYGVVEKMRHVPSEQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKATDVASFVKSILGD", "length": 334 }, "evidence": [ { "id": "A0A5K1UKA4", "url": "https://omabrowser.org/oma/group/A0A5K1UKA4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9FJV0-1", "protein_name": "Mitogen-activated protein kinase kinase 6", "gene_name": "MKK6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVKIKSNLKQLKLSVPAQESPISSFLTASGTFHDGDFLLNQKGLRLTSDEKQSRQSDSKELDFEITAEDLETVKVIGKGSGGVVQLVRHKWVGKFFAMKVIQMNIQEEIRKQIVQELKINQASSQCPHVVVCYHSFYHNGAFSLVLEYMDRGSLADVIRQVKTILEPYLAVVCKQVLLGLVYLHNERHVIHRDIKPSNLLVNHKGEVKISDFGVSASLASSMGQRDTFVGTYNYMSPERISGSTYDYSSDIWSLGMSVLECAIGRFPYLESEDQQNPPSFYELLAAIVENPPPTAPSDQFSPEFCSFVSACIQKDPPARASSLDLLSHPFIKKFEDKDIDLGILVGTLEPPVNYLR", "length": 356 }, "evidence": [ { "id": "A0A5K1UKA4", "url": "https://omabrowser.org/oma/group/A0A5K1UKA4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" }, { "name": "MAP kinase kinase activity", "id": "GO:0004708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004708", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" }, { "name": "osteoblast differentiation", "id": "GO:0001649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001649", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" }, { "name": "stress-activated MAPK cascade", "id": "GO:0051403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051403", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" }, { "name": "p38MAPK cascade", "id": "GO:0038066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038066", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" }, { "name": "negative regulation of cold-induced thermogenesis", "id": "GO:0120163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120163", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" }, { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UKA4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-SSC-1247960", "name": "Activation of p38 MAPK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1247960", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1247960" } ] }, { "id": "R-SSC-3228469", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-3228469", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3228469" } ] }, { "id": "R-SSC-3238999", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-3238999", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3238999" } ] }, { "id": "R-SSC-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-450296", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450296" } ] }, { "id": "R-SSC-450333", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-450333", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450333" } ] }, { "id": "R-SSC-450346", "name": "activated human TAK1 phosphorylates MKK3/MKK6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-450346", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450346" } ] }, { "id": "R-SSC-727819", "name": "TAK1 phosphorylates MKK6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-SSC-167998" ], "output_participant_list": [ "R-SSC-206255" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-727819", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-727819" } ] }, { "id": "R-SSC-8877691", "name": "MAP2K6 phosphorylates PIP4K2B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8877691", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8877691" } ] }, { "id": "R-SSC-9836322", "name": "p-PKR dimer phosphorylates MKK6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9836322", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9836322" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-167998", "participant_name": "MAP2K6 [cytosol]", "crossref": [ { "id": "A0A5K1UKA4", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000017254", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000030562", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000035633", "database": "ENSEMBL", "url": "" }, { "id": "XP_013836270.1", "database": "RefSeq", "url": "" }, { "id": "98102", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-206255", "participant_name": "phospho-p-S207,T211-MAP2K6 [cytosol]", "crossref": [ { "id": "ENSSSCT00000035633", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000017254", "database": "ENSEMBL", "url": "" }, { "id": "98102", "database": "VGNC", "url": "" }, { "id": "A0A5K1UKA4", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000030562", "database": "ENSEMBL", "url": "" }, { "id": "XP_013836270.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1UKA4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 334, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1UKA4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1UKA4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1UKA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UKA4" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 314, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1VU77-1", "uniprot_ac": "A0A5K1VU77", "uniprot_id": "A0A5K1VU77_PIG", "mass": { "chemical_mass": 19208.0, "monoisotopic_mass": 19208.0 }, "refseq": { "ac": "NP_001422209", "name": "peptidylprolyl isomerase H", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422209" }, "gene_names": [ { "name": "PPIH", "type": "recommended", "evidence": [ { "id": "A0A5K1VU77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ] }, { "name": "PPIH", "type": "synonym", "evidence": [ { "id": "NP_001422209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422209" } ] } ], "protein_names": [ { "name": "Peptidyl-prolyl cis-trans isomerase", "type": "recommended", "evidence": [ { "id": "A0A5K1VU77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77/entry#names_and_taxonomy" } ] }, { "name": "5.2.1.8", "type": "synonym", "evidence": [ { "id": "A0A5K1VU77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77/entry#names_and_taxonomy" } ] }, { "name": "PPIase", "type": "synonym", "evidence": [ { "id": "A0A5K1VU77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77/entry#names_and_taxonomy" } ] }, { "name": "peptidyl-prolyl cis-trans isomerase H", "type": "synonym", "evidence": [ { "id": "NP_001422209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422209" } ] }, { "name": "peptidylprolyl isomerase H", "type": "synonym", "evidence": [ { "id": "NP_001422209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422209" } ] } ], "function": [ { "annotation": "PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone.", "evidence": [ { "database": "UniProtKB", "id": "F1SF95", "url": "https://www.uniprot.org/uniprotkb/F1SF95#function" }, { "database": "UniProtKB", "id": "ARBA00059766", "url": "https://www.uniprot.org/uniprotkb/ARBA00059766#function" }, { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77#function" } ] }, { "annotation": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.", "evidence": [ { "database": "UniProtKB", "id": "F1SF95", "url": "https://www.uniprot.org/uniprotkb/F1SF95#function" }, { "database": "UniProtKB", "id": "RU363019", "url": "https://www.uniprot.org/uniprotkb/RU363019#function" }, { "database": "UniProtKB", "id": "A0A8W4FM84", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FM84#function" }, { "database": "UniProtKB", "id": "A0A5G2QQA6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQA6#function" }, { "database": "UniProtKB", "id": "A0A5G2R048", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R048#function" }, { "database": "UniProtKB", "id": "A0A5G2RII9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RII9#function" }, { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PPIH", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77", "locus": { "chromosome": "6", "start_pos": 168742005, "end_pos": 168760286, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003964", "url": "https://www.ensembl.org/id/ENSSSCG00000003964" } ] } } ], "crossref": [ { "id": "A0A5K1VU77", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1VU77", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003964", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003964", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01926", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01926", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523448", "url": "https://www.ncbi.nlm.nih.gov/gene/100523448", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SVWGQVI", "url": "https://omabrowser.org/oma/group/SVWGQVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11071:SF561", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11071:SF561", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001422209", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422209", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QQA6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R048", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R048", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R048-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R048-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RII9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RII9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RII9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RII9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VU77-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FM84", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FM84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FM84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FM84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SF95", "url": "https://www.uniprot.org/uniprotkb/F1SF95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SF95-1", "url": "https://www.uniprot.org/uniprotkb/F1SF95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM", "length": 177, "header": "tr|A0A5K1VU77-1|A0A5K1VU77_PIG Isoform 1 of Peptidyl-prolyl cis-trans isomerase OS=Sus scrofa OX=9823 GN=PPIH PE=1 SV=1 CANONICAL=A0A5K1VU77-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77/entry#A0A5G2QQA6-1", "sequence": { "sequence": "MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRKDGVPIGYKGIADTSLLSAQGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGESESCPGPDPLHQGGNVPTGPNNKPKLPVVISQCGEM", "length": 162, "header": "tr|A0A5G2QQA6-1|A0A5K1VU77_PIG Computationally mapped isoform of Peptidyl-prolyl cis-trans isomerase OS=Sus scrofa OX=9823 GN=PPIH PE=1 SV=1 CANONICAL=A0A5K1VU77-1" }, "locus": { "chromosome": "6", "start_pos": 168760264, "end_pos": 168749701, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079841.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079841.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066246.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066246.1" } ] } }, { "isoform_ac": "A0A5G2R048-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77/entry#A0A5G2R048-1", "sequence": { "sequence": "MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVDVPHSQVADTSLLSAQGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGESESCPGPDPLHQGGNVPTGPNNKPKLPVVISQCGEM", "length": 150, "header": "tr|A0A5G2R048-1|A0A5K1VU77_PIG Computationally mapped isoform of Peptidyl-prolyl cis-trans isomerase OS=Sus scrofa OX=9823 GN=PPIH PE=1 SV=2 CANONICAL=A0A5K1VU77-1" }, "locus": { "chromosome": "6", "start_pos": 168760264, "end_pos": 168749701, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080964.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080964.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067571.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067571.2" } ] } }, { "isoform_ac": "A0A5G2RII9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77/entry#A0A5G2RII9-1", "sequence": { "sequence": "MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMNQDPGHCVSDTRARRGWGRGAS", "length": 134, "header": "tr|A0A5G2RII9-1|A0A5G2RII9_PIG Computationally mapped isoform of Peptidyl-prolyl cis-trans isomerase OS=Sus scrofa OX=9823 GN=PPIH PE=1 SV=1 CANONICAL=A0A5K1VU77-1" }, "locus": { "chromosome": "6", "start_pos": 168760264, "end_pos": 168753708, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088989.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088989.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071417.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071417.1" } ] } }, { "isoform_ac": "A0A5K1VU77-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77/entry#A0A5K1VU77-1", "sequence": { "sequence": "MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM", "length": 177, "header": "tr|A0A5K1VU77-1|A0A5K1VU77_PIG Isoform 1 of Peptidyl-prolyl cis-trans isomerase OS=Sus scrofa OX=9823 GN=PPIH PE=1 SV=1 CANONICAL=A0A5K1VU77-1" }, "locus": { "chromosome": "6", "start_pos": 168760264, "end_pos": 168749701, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023240.3", "url": "https://www.ensembl.org/id/ENSSSCT00000023240.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019638.2", "url": "https://www.ensembl.org/id/ENSSSCP00000019638.2" } ] } }, { "isoform_ac": "A0A8W4FM84-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77/entry#A0A8W4FM84-1", "sequence": { "sequence": "MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRKDGVPIGYKGIADTSLLSAQGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIETPCLPRVPGPTLALWRVLRLGLCRLLHLLAESSSNVPTGPNNKPKLPVVISQCGEM", "length": 194, "header": "tr|A0A8W4FM84-1|A0A5K1VU77_PIG Computationally mapped isoform of Peptidyl-prolyl cis-trans isomerase OS=Sus scrofa OX=9823 GN=PPIH PE=1 SV=1 CANONICAL=A0A5K1VU77-1" }, "locus": { "chromosome": "6", "start_pos": 168760264, "end_pos": 168749701, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103209.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103209.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080605.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080605.1" } ] } }, { "isoform_ac": "F1SF95-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77/entry#F1SF95-1", "sequence": { "sequence": "MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIETPCLPRVPGPTLALWRVLRLGLCRLLHLLAESSSNVPTGPNNKPKLPVVISQCGEM", "length": 211, "header": "tr|F1SF95-1|A0A5K1VU77_PIG Computationally mapped isoform of Peptidyl-prolyl cis-trans isomerase OS=Sus scrofa OX=9823 GN=PPIH PE=1 SV=3 CANONICAL=A0A5K1VU77-1" }, "locus": { "chromosome": "6", "start_pos": 168760264, "end_pos": 168749701, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004385.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004385.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004285.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004285.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SF95", "url": "https://www.uniprot.org/uniprotkb/F1SF95" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N0X8-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase", "gene_name": "Ppih", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM", "length": 177 }, "evidence": [ { "id": "A0A5K1VU77", "url": "https://omabrowser.org/oma/group/A0A5K1VU77/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM", "length": 177 }, "evidence": [ { "id": "A0A5K1VU77", "url": "https://omabrowser.org/oma/group/A0A5K1VU77/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0P5D0-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM", "length": 177 }, "evidence": [ { "id": "A0A5K1VU77", "url": "https://omabrowser.org/oma/group/A0A5K1VU77/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D868-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "Ppih", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIEFQAPLGKRVQAWTHSLTCPALTGILALILMPTE", "length": 188 }, "evidence": [ { "id": "A0A5K1VU77", "url": "https://omabrowser.org/oma/group/A0A5K1VU77/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "pmid": "" }, { "name": "U4/U6 snRNP", "id": "GO:0071001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071001", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "pmid": "" }, { "name": "positive regulation of viral genome replication", "id": "GO:0045070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045070", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "pmid": "" }, { "name": "cyclosporin A binding", "id": "GO:0016018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016018", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VU77", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1VU77-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 177, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1VU77-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1VU77" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1VU77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VU77" }, { "id": "PS50072", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50072" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPIase cyclophilin-type", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 176, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SIT1-1", "uniprot_ac": "A0A4X1SIT1", "uniprot_id": "A0A4X1SIT1_PIG", "mass": { "chemical_mass": 98644.0, "monoisotopic_mass": 98644.0 }, "refseq": { "ac": "XP_020949520", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949520" }, "gene_names": [ { "name": "WWP2", "type": "recommended", "evidence": [ { "id": "A0A4X1SIT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ] }, { "name": "WWP2", "type": "synonym", "evidence": [ { "id": "XP_020949520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949520" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase", "type": "recommended", "evidence": [ { "id": "A0A4X1SIT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.26", "type": "synonym", "evidence": [ { "id": "A0A4X1SIT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1/entry#names_and_taxonomy" } ] }, { "name": "NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020949520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949520" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "WWP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1", "locus": { "chromosome": "6", "start_pos": 17066799, "end_pos": 17227926, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000022609", "url": "https://www.ensembl.org/id/ENSSSCG00000022609" } ] } } ], "crossref": [ { "id": "ENSSSCG00000022609", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022609", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04021", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04021", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626361", "url": "https://www.ncbi.nlm.nih.gov/gene/100626361", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626361", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626361", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YQQFRFL", "url": "https://omabrowser.org/oma/group/YQQFRFL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SIT1", "url": "https://www.orthodb.org/?gene=A0A4X1SIT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R3N3", "url": "https://www.orthodb.org/?gene=A0A5G2R3N3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254:SF396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254:SF396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8948751", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8948751", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013420", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013420", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020949520", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949520", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SIR6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SIR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SIT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3N3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3N3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1XTD5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XTD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1XTD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XTD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LG84", "url": "https://www.uniprot.org/uniprotkb/I3LG84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LG84-1", "url": "https://www.uniprot.org/uniprotkb/I3LG84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASASSSRAGVALPFEKSQLILKVVSAKPKVHSRQPRINSFVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENTQLTLNLQTENKGGVVSGGELTIFLDGPTVDLGSVPNGSAVTDGPQPPSRESSGTAVATENRHQPPSTNCFGGRSRTHRHSGGAARTATAASEQSPGTSSRHHQPIKNPSHSGLANGTVSDEPTAATDPEEPSVVGVTSPPAASSSVTLNPTAEALPATATPAEGEEPSTSGTQQLPAASQAPDALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRSQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRVYYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFVELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEGFGQE", "length": 870, "header": "tr|A0A4X1SIT1-1|A0A4X1SIT1_PIG Isoform 1 of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=WWP2 PE=1 SV=1 CANONICAL=A0A4X1SIT1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SIR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1/entry#A0A4X1SIR6-1", "sequence": { "sequence": "MASASSSRAGVALPFEKSQLILKVVSAKPKVHSRQPRINSFVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENTQLTLNLQTENKGGVVSGGELTIFLDGPTVDLGSVPNGSAVTDGPQPPSRESSGTAVATENRHQPPSTNCFGGRSRTHRHSGGAARTATAASEQSPGTSSRHHQPIKNPSHSGLANGTVSDEPTAATDPEEPSVVGVTSPPAASSSVTLNPTAEALPATATPAEGEEPSTSGTQQLPAASQAPDALPAGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRSQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRVYYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFVELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEGFGQE", "length": 840, "header": "tr|A0A4X1SIR6-1|A0A4X1SIR6_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=WWP2 PE=1 SV=1 CANONICAL=A0A4X1SIT1-1" }, "locus": { "chromosome": "6", "start_pos": 17201265, "end_pos": 17070495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032019.3", "url": "https://www.ensembl.org/id/ENSSSCT00000032019.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019876.2", "url": "https://www.ensembl.org/id/ENSSSCP00000019876.2" } ] } }, { "isoform_ac": "A0A4X1SIT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1/entry#A0A4X1SIT1-1", "sequence": { "sequence": "MASASSSRAGVALPFEKSQLILKVVSAKPKVHSRQPRINSFVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENTQLTLNLQTENKGGVVSGGELTIFLDGPTVDLGSVPNGSAVTDGPQPPSRESSGTAVATENRHQPPSTNCFGGRSRTHRHSGGAARTATAASEQSPGTSSRHHQPIKNPSHSGLANGTVSDEPTAATDPEEPSVVGVTSPPAASSSVTLNPTAEALPATATPAEGEEPSTSGTQQLPAASQAPDALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRSQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRVYYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFVELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEGFGQE", "length": 870, "header": "tr|A0A4X1SIT1-1|A0A4X1SIT1_PIG Isoform 1 of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=WWP2 PE=1 SV=1 CANONICAL=A0A4X1SIT1-1" }, "locus": { "chromosome": "6", "start_pos": 17201265, "end_pos": 17070495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059644.2", "url": "https://www.ensembl.org/id/ENSSSCT00000059644.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047666.1", "url": "https://www.ensembl.org/id/ENSSSCP00000047666.1" } ] } }, { "isoform_ac": "A0A5G2QPF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1/entry#A0A5G2QPF3-1", "sequence": { "sequence": "MASASSSRAGVALPFEKSQLILKVVSAKPKVHSRQPRINSFVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKRPGVCSDSAPRACGPCSFRKAESCPLPCQGPEPLGPGPPVGGCSGVAPLFLPQGRTFPPPLPPSPRSGGV", "length": 183, "header": "tr|A0A5G2QPF3-1|A0A4X1SIT1_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=WWP2 PE=1 SV=2 CANONICAL=A0A4X1SIT1-1" }, "locus": { "chromosome": "6", "start_pos": 17201265, "end_pos": 17193324, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073956.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073956.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060167.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060167.2" } ] } }, { "isoform_ac": "A0A5G2R3N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1/entry#A0A5G2R3N3-1", "sequence": { "sequence": "MASASSSRAGVALPFEKSQLILKVVSAKPKVHSRQPRINSFVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENTQLTLNLQTENKGGVVSGGELTIFLDGPTVDLGSVPNGSAVTDGPQPPSRESSGTAVATENRHQPPSTNCFGGRSRTHRHSGGAARTATAASEQSPGTSSRHHQPIKNPSHSGLANGTVSDEPTAATDPEEPSVVGVTSPPAASSSVTLNPTAEALPATATPAEGEEPSTSGTQQLPAASQAPDALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPG", "length": 335, "header": "tr|A0A5G2R3N3-1|A0A4X1SIT1_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=WWP2 PE=1 SV=1 CANONICAL=A0A4X1SIT1-1" }, "locus": { "chromosome": "6", "start_pos": 17201265, "end_pos": 17099366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074246.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074246.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071813.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071813.1" } ] } }, { "isoform_ac": "A0A8D1XTD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1/entry#A0A8D1XTD5-1", "sequence": { "sequence": "MASASSSRAGVALPFEKSQLILKVVSAKPKVHSRQPRINSFVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENTQLTLNLQTENKGGVVSGGELTIFLDGPTVDLGSVPNGSAVTDGPQPPSRESSGTAVATENRHQPPSTNCFGGRSRTHRHSGGAARTATAASEQSPGTSSRHHQPIKNPSHSGLANGTVSDEPTAATDPEEPSVVGVTSPPAASSSVTLNPTAEALPATATPAEGEEPSTSGTQQLPAASQAPDALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRSQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRVYYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGEWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFVELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEGFGQE", "length": 791, "header": "tr|A0A8D1XTD5-1|A0A4X1SIT1_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=WWP2 PE=1 SV=1 CANONICAL=A0A4X1SIT1-1" }, "locus": { "chromosome": "6", "start_pos": 17201265, "end_pos": 17070495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049092.2", "url": "https://www.ensembl.org/id/ENSSSCT00000049092.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053445.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053445.2" } ] } }, { "isoform_ac": "I3LG84-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1/entry#I3LG84-1", "sequence": { "sequence": "MGRLRIGERRGRKNQEEVFQCPGDDMASASSSRAGVALPFEKSQLILKVVSAKPKVHSRQPRINSFVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENTQLTLNLQTENKGGVVSGGELTIFLDGPTVDLGSVPNGSAVTDGPQPPSRESSGTAVATENRHQPPSTNCFGGRSRTHRHSGGAARTATAASEQSPGTSSRHHQPIKNPSHSGLANGTVSDEPTAATDPEEPSVVGVTSPPAASSSVTLNPTAEALPATATPAEGEEPSTSGTQQLPAASQAPDALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRSQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRVYYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFVELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEGFGQE", "length": 895, "header": "tr|I3LG84-1|A0A4X1SIT1_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=WWP2 PE=1 SV=3 CANONICAL=A0A4X1SIT1-1" }, "locus": { "chromosome": "6", "start_pos": 17227456, "end_pos": 17070495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025575.3", "url": "https://www.ensembl.org/id/ENSSSCT00000025575.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023077.3", "url": "https://www.ensembl.org/id/ENSSSCP00000023077.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 277, "start_aa": "Thr", "end_pos": 277, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr277", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LG84", "url": "https://www.uniprot.org/uniprotkb/I3LG84" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626361", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626361", "resource": "KEGG Pathway" }, { "id": "R-SSC-8948751", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8948751", "resource": "Reactome", "description": "Regulation of PTEN stability and activity" }, { "id": "R-SSC-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-SSC-9013420", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013420", "resource": "Reactome", "description": "RHOU GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "potassium channel inhibitor activity", "id": "GO:0019870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019870", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "molecular function inhibitor activity", "id": "GO:0140678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140678", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "negative regulation of potassium ion export across plasma membrane", "id": "GO:1903765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903765", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "extracellular transport", "id": "GO:0006858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006858", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "regulation of monoatomic ion transmembrane transport", "id": "GO:0034765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034765", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-6807134", "name": "NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-SSC-6807280" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6807134", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807134" } ] }, { "id": "R-SSC-9018746", "name": "RHOQ binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9018746", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018746" } ] }, { "id": "R-SSC-9018766", "name": "RHOU binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9018766", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018766" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-6807280", "participant_name": "PTEN [cytosol]", "crossref": [ { "id": "ENSSSCP00000011128", "database": "ENSEMBL", "url": "" }, { "id": "F2Z5H1", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000010440", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000011425", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SIT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 117, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SIT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" }, { "id": "PS50237", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50237" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HECT", "eco_id": "ECO_0000259", "start_pos": 536, "end_pos": 870, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SIT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIT1" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 300, "end_pos": 333, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 277 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 153, "end_pos": 155 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RL17-1", "uniprot_ac": "A0A5G2RL17", "uniprot_id": "A0A5G2RL17_PIG", "mass": { "chemical_mass": 95906.0, "monoisotopic_mass": 95906.0 }, "refseq": {}, "gene_names": [ { "name": "ESYT2", "type": "recommended", "evidence": [ { "id": "A0A5G2RL17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ] } ], "protein_names": [ { "name": "Extended synaptotagmin-2", "type": "recommended", "evidence": [ { "id": "A0A5G2RL17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS).", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17#function" }, { "database": "UniProtKB", "id": "ARBA00058073", "url": "https://www.uniprot.org/uniprotkb/ARBA00058073#function" }, { "database": "UniProtKB", "id": "A0A287BCJ5", "url": "https://www.uniprot.org/uniprotkb/A0A287BCJ5#function" }, { "database": "UniProtKB", "id": "A0A287BNC1", "url": "https://www.uniprot.org/uniprotkb/A0A287BNC1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ESYT2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17", "locus": { "chromosome": "18", "start_pos": 643307, "end_pos": 565145, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016406", "url": "https://www.ensembl.org/id/ENSSSCG00000016406" } ] } } ], "crossref": [ { "id": "A0A5G2RL17", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RL17", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016406", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016406", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04030", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04030", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04050", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04050", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08391", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08391", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21680", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21680", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45761", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45761", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45761:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45761:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9845576", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9845576", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZI47", "url": "https://www.uniprot.org/uniprotkb/A0A286ZI47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZI47-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZI47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BCJ5", "url": "https://www.uniprot.org/uniprotkb/A0A287BCJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BCJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BCJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BNC1", "url": "https://www.uniprot.org/uniprotkb/A0A287BNC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BNC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BNC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q791", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q791", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q791-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q791-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RL17-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGPRAPGPEAGAAGAEPPGAALSVDVTGLLAQLARSFALLLPVYALGYLGLSFSWVLLALGLLVWCRRSRGLKATRLCRALALLEDEERAVRLGVRACDLPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKLFRETIEPAVRGAHPHLSTFSFTRVDVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAGVQSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDIPGLNGLSDTIILDIISNYLVLPNRVTVPLVSEVQIAQLRFPVPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGVLRVGNQIFQSKVIKESLSPKWNEVYEALVYEHPGQELEIELFDEDPDKDDFLGSLMIDLIEVEKERLLDEWFALDEVPKGKLHLKLEWLTLVPNAVNLEKVLTDIRADKDQATDGLSSSLLILYLDSARNLPSIYEGDFGCGYLKERRASGLVFCENTASVYRALFSGKKMNSNPSPLVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQELEVEVRDEQHQCSLGNLRIPLSQLLASEDMTMNQRFQLSNSGPNSSLKMKLALRVLHLEKQERSPDHQHSAQVKRPSVSKEGRKIPVRPQMSASPGTGDSSTAPSSPVVGGGDKPGVEERAPPAEASPQGPQDLGRSSSSLQASGTGSPSHISVKEPTPSIASDISLPIATQELRQRLRQLENGTTLGQSPLGQIQLTIRHSSQRNKLVVVVHSCRNLIAFSEDGSDPYVRLYLLPDKRRSGRRKTHVSKKTLNPVFDQSFDFSVSLPEAQRRTLDVAVKNSGGFLSKDKGLLGKVLVGLASEELAKGWTQW", "length": 863, "header": "tr|A0A5G2RL17-1|A0A5G2RL17_PIG Isoform 1 of Extended synaptotagmin-2 OS=Sus scrofa OX=9823 GN=ESYT2 PE=1 SV=2 CANONICAL=A0A5G2RL17-1" }, "isoforms": [ { "isoform_ac": "A0A286ZI47-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17/entry#A0A286ZI47-1", "sequence": { "sequence": "MSGPRAPGPEAGAAGAEPPGAALSVDVTGLLAQLARSFALLLPVYALGYLGLSFSWVLLALGLLVWCRRSRGLKATRLCRALALLEDEERAVRLGVRACDLPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKLFRETIEPAVRGAHPHLSTFSFTRVDVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAGVQSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDIPGLNGLSDTIILDIISNYLVLPNRVTVPLVSEVQIAQLRFPVPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGVLRVGNQIFQSKVIKESLSPKWNEVYEALVYEHPGQELEIELFDEDPDKDDFLGSLMIDLIEVEKERLLDEWFALDEVPKGKLHLKLEWLTLVPNAVNLEKVLTDIRADKDQATDGLSSSLLILYLDSARNLPSGKKMNSNPSPLVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQELEVEVRDEQHQCSLGNLRIPLSQLLASEDMTMNQRFQLSNSGPNSSLKMKLALRVLHLEKQERSPDHQHSAQVKRPSVSKEGRKIPVRPQMSASPGTGDSSTAPSSPVVGGGDKPGVEERAPPAEASPQGPQDLGRSSSSLQASGTGSPSHISVKEPTPSIASDISLPIATQELRQRLRQLENGTTLGQSPLGQIQLTIRHSSQRNKLVVVVHSCRNLIAFSEDGSDPYVRLYLLPDKRRSGRRKTHVSKKTLNPVFDQRYASSPWGDGR", "length": 787, "header": "tr|A0A286ZI47-1|A0A5G2RL17_PIG Computationally mapped isoform of Extended synaptotagmin-2 OS=Sus scrofa OX=9823 GN=ESYT2 PE=1 SV=1 CANONICAL=A0A5G2RL17-1" }, "locus": { "chromosome": "18", "start_pos": 638607, "end_pos": 565265, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046380.1", "url": "https://www.ensembl.org/id/ENSSSCT00000046380.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031179.1", "url": "https://www.ensembl.org/id/ENSSSCP00000031179.1" } ] } }, { "isoform_ac": "A0A287BCJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17/entry#A0A287BCJ5-1", "sequence": { "sequence": "MSGPRAPGPEAGAAGAEPPGAALSVDVTGLLAQLARSFALLLPVYALGYLGLSFSWVLLALGLLVWCRRSRGLKATRLCRALALLEDEERAVRLGVRACDLPAWVHFPDTERAEWLNKFIEKLFRETIEPAVRGAHPHLSTFSFTRVDVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAGVQSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDIPGLNGLSDTIILDIISNYLVLPNRVTVPLVSEVQIAQLRFPVPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGVLRVGNQIFQSKVIKESLSPKWNEVYEALVYEHPGQELEIELFDEDPDKDDFLGSLMIDLIEVEKERLLDEWFALDEVPKGKLHLKLEWLTLVPNAVNLEKVLTDIRADKDQATDGLSSSLLILYLDSARNLPSNPLEFNADVLKKAAIQKALKSGKKMNSNPSPLVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQELEVEVRDEQHQCSLGNLRIPLSQLLASEDMTMNQRFQLSNSGPNSSLKMKLALRVLHLEKQERSPDHQHSAQVKRPSVSKEGRKIPVRPQMSASPGTGDSSTAPSSPVVGGGDKPGVEERAPPAEASPQGPQDLGRSSSSLQASGTGSPSHISVKEPTPSIASDISLPIATQELRQRLRQLENGTTLGQSPLGQIQLTIRHSSQRNKLVVVVHSCRNLIAFSEDGSDPYVRLYLLPDKRRSGRRKTHVSKKTLNPVFDQSFDFSVSLPEAQRRTLDVAVKNSGGFLSKDKGLLGKVLVGLASEELAKGWTQWYDLTEDGTRPHVVT", "length": 853, "header": "tr|A0A287BCJ5-1|A0A5G2RL17_PIG Computationally mapped isoform of Extended synaptotagmin-2 OS=Sus scrofa OX=9823 GN=ESYT2 PE=1 SV=3 CANONICAL=A0A5G2RL17-1" }, "locus": { "chromosome": "18", "start_pos": 640723, "end_pos": 565265, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063329.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063329.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054054.3", "url": "https://www.ensembl.org/id/ENSSSCP00000054054.3" } ] } }, { "isoform_ac": "A0A287BNC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17/entry#A0A287BNC1-1", "sequence": { "sequence": "MSGPRAPGPEAGAAGAEPPGAALSVDVTGLLAQLARSFALLLPVYALGYLGLSFSWVLLALGLLVWCRRSRGLKATRLCRALALLEDEERAVRLGVRACDLPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKLFRETIEPAVRGAHPHLSTFSFTRVDVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAGVQSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDIPGLNGLSDTIILDIISNYLVLPNRVTVPLVSEVQIAQLRFPVPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGVLRVGNQIFQSKVIKESLSPKWNEVYEALVYEHPGQELEIELFDEDPDKDDFLGSLMIDLIEVEKERLLDEWFALDEVPKGKLHLKLEWLTLVPNAVNLEKVLTDIRADKDQATDGLSSSLLILYLDSARNLPVRDEQHQCSLGNLRIPLSQLLASEDMTMNQRFQLSNSGPNSSLKMKLALRVLHLEKQERSPDHQHSAQVKRPSVSKEGRKIPVRPQMSASPGTGDSSTAPSSPVVGGGDKPGVEERAPPAEASPQGPQDLGRSSSSLQASGTGSPSHISVKEPTPSIASDISLPIATQELRQRLRQLENGTTLGQSPLGQIQLTIRHSSQRNKLVVVVHSCRNLIAFSEDGSDPYVRLYLLPDKRRSGRRKTHVSKKTLNPVFDQSFDFSVSLPEAQRRTLDVAVKNSGGFLSKDKGLLGKVLVGLASEELAKGWTQWYDLTEDGTRPHVVT", "length": 789, "header": "tr|A0A287BNC1-1|A0A5G2RL17_PIG Computationally mapped isoform of Extended synaptotagmin-2 OS=Sus scrofa OX=9823 GN=ESYT2 PE=1 SV=2 CANONICAL=A0A5G2RL17-1" }, "locus": { "chromosome": "18", "start_pos": 640723, "end_pos": 565265, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061272.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061272.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057942.2", "url": "https://www.ensembl.org/id/ENSSSCP00000057942.2" } ] } }, { "isoform_ac": "A0A5G2Q791-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17/entry#A0A5G2Q791-1", "sequence": { "sequence": "MSGPRAPGPEAGAAGAEPPGAALSVDVTGLLAQLARSFALLLPVYALGYLGLSFSWVLLALGLLVWCRRSRGLKATRLCRALALLEDEERAVRLGVRACDLPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKLFRETIEPAVRGAHPHLSTFSFTRVDVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAGVQSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDIPGLNGLSDTIILDIISNYLVLPNRVTVPLVSEVQIAQLRFPVPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGVLRVGNQIFQSKVIKESLSPKWNEVYEALWFALDEVPKGKLHLKLEWLTLVPNAVNLEKVLTDIRADKDQATDGLSSSLLILYLDSARNLPSGKKMNSNPSPLVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQELEVEVRDEQHQCSLGNLRIPLSQLLASEDMTMNQRFQLSNSGPNSSLKMKLALRVLHLEKQERSPDHQHSAQVKRPSVSKEGRKIPVRPQMSASPGTGDSSTAPSSPVVGGGDKPGVEERAPPAEASPQGPQDLGRSSSSLQASGTGSPSHISVKEPTPSIASDISLPIATQELRQRLRQLENGTTLGQSPLGQIQLTIRHSSQRNKLVVVVHSCRNLIAFSEDGSDPYVRLYLLPDKRRSGRRKTHVSKKTLNPVFDQRYASSPWGDGR", "length": 745, "header": "tr|A0A5G2Q791-1|A0A5G2Q791_PIG Computationally mapped isoform of Extended synaptotagmin 2 OS=Sus scrofa OX=9823 GN=ESYT2 PE=1 SV=1 CANONICAL=A0A5G2RL17-1" }, "locus": { "chromosome": "18", "start_pos": 638607, "end_pos": 565265, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075824.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075824.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059655.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059655.1" } ] } }, { "isoform_ac": "A0A5G2RL17-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17/entry#A0A5G2RL17-1", "sequence": { "sequence": "MSGPRAPGPEAGAAGAEPPGAALSVDVTGLLAQLARSFALLLPVYALGYLGLSFSWVLLALGLLVWCRRSRGLKATRLCRALALLEDEERAVRLGVRACDLPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKLFRETIEPAVRGAHPHLSTFSFTRVDVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAGVQSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDIPGLNGLSDTIILDIISNYLVLPNRVTVPLVSEVQIAQLRFPVPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGVLRVGNQIFQSKVIKESLSPKWNEVYEALVYEHPGQELEIELFDEDPDKDDFLGSLMIDLIEVEKERLLDEWFALDEVPKGKLHLKLEWLTLVPNAVNLEKVLTDIRADKDQATDGLSSSLLILYLDSARNLPSIYEGDFGCGYLKERRASGLVFCENTASVYRALFSGKKMNSNPSPLVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQELEVEVRDEQHQCSLGNLRIPLSQLLASEDMTMNQRFQLSNSGPNSSLKMKLALRVLHLEKQERSPDHQHSAQVKRPSVSKEGRKIPVRPQMSASPGTGDSSTAPSSPVVGGGDKPGVEERAPPAEASPQGPQDLGRSSSSLQASGTGSPSHISVKEPTPSIASDISLPIATQELRQRLRQLENGTTLGQSPLGQIQLTIRHSSQRNKLVVVVHSCRNLIAFSEDGSDPYVRLYLLPDKRRSGRRKTHVSKKTLNPVFDQSFDFSVSLPEAQRRTLDVAVKNSGGFLSKDKGLLGKVLVGLASEELAKGWTQW", "length": 863, "header": "tr|A0A5G2RL17-1|A0A5G2RL17_PIG Isoform 1 of Extended synaptotagmin-2 OS=Sus scrofa OX=9823 GN=ESYT2 PE=1 SV=2 CANONICAL=A0A5G2RL17-1" }, "locus": { "chromosome": "18", "start_pos": 640587, "end_pos": 565265, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072089.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072089.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072958.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072958.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 709, "start_aa": "Thr", "end_pos": 709, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr709", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZI47", "url": "https://www.uniprot.org/uniprotkb/A0A286ZI47" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9845576", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9845576", "resource": "Reactome", "description": "Glycosphingolipid transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane tethering", "id": "GO:0061817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061817", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "pmid": "" }, { "name": "phosphatidylethanolamine binding", "id": "GO:0008429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008429", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "pmid": "" }, { "name": "phosphatidylcholine binding", "id": "GO:0031210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031210", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RL17-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 863, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RL17-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RL17" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RL17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 287, "end_pos": 407, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RL17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL17" }, { "id": "PS51847", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51847" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SMP-LTD", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 288, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 709 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 734, "end_pos": 736 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RKP4-1", "uniprot_ac": "A0A5G2RKP4", "uniprot_id": "A0A5G2RKP4_PIG", "mass": { "chemical_mass": 58082.0, "monoisotopic_mass": 58082.0 }, "refseq": {}, "gene_names": [ { "name": "TXNRD2", "type": "recommended", "evidence": [ { "id": "A0A5G2RKP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" } ] } ], "protein_names": [ { "name": "thioredoxin-disulfide reductase (NADPH)", "type": "recommended", "evidence": [ { "id": "A0A5G2RKP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4/entry#names_and_taxonomy" } ] }, { "name": "1.8.1.9", "type": "synonym", "evidence": [ { "id": "A0A5G2RKP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TXNRD2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4", "locus": { "chromosome": "14", "start_pos": 51356831, "end_pos": 51383262, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010131", "url": "https://www.ensembl.org/id/ENSSSCG00000010131" } ] } } ], "crossref": [ { "id": "A0A5G2RKP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RKP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010131", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010131", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR42737", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42737", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42737:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42737:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02852", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02852", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07992", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07992", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZJ07", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJ07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZJ07-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJ07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RHN4", "url": "https://www.uniprot.org/uniprotkb/F1RHN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RHN4-1", "url": "https://www.uniprot.org/uniprotkb/F1RHN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIFCDAFLPPGGAGLVLGALTPALARSSHRLSPLGTYLSSPPLLRCAQAPPGPACSPLPFTQAGQQCYDLLVIGGGSGGLACAKEAAQLGKKVAVVDYVSPSPRGTRWGLGGTCVNVGCIPKKLMHQAALLGGVIRDAPHYGWEVAQPALHSWKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNFKASFVNKHTVCGVLKGGKEILLSAEHIVIATGGRPRYPAHIEGAVEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGLGLDATIMIRSIPLRAFDQQMASLVIEHMAVHGTRILKGCMPLRVEKLPDGQLQVTWVDLASDRKDVGTFDTVLWATGRVPEIGSLNLEKAGVHTNPHTQKILVDAQDATSVPHIYAIGDVAEGRPELTPTAVMAGRLLAQRLCGRSSDLMDYDNVPTTVFTPLEYGCVGLSEEAAVARHGEEGVEVYHAYYKPLEFTVPERDASQCYIKMVCLREPPQLVLGLHFLGPNAGEVTQGFALALKCGASYEQVMRTVGIHPTCAEEVAKLRISKRSG", "length": 541, "header": "tr|A0A5G2RKP4-1|A0A5G2RKP4_PIG Isoform 1 of thioredoxin-disulfide reductase (NADPH) OS=Sus scrofa OX=9823 GN=TXNRD2 PE=1 SV=2 CANONICAL=A0A5G2RKP4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZJ07-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4/entry#A0A286ZJ07-1", "sequence": { "sequence": "CFALCLIEWGRGARRCSRGPAVAAGRTAGQQCYDLLVIGGGSGGLACAKEAAQLGKKVAVVDYVSPSPRGTRWGLGGTCVNVGCIPKKLMHQAALLGGVIRDAPHYGWEVAQPALHSWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNFKASFVNKHTVCGVLKGGKEILLSAEHIVIATGGRPRYPAHIEGAVEYGITNVALECAGFLTGLGLDATIMIRSIPLRAFDQQMASLVIEHMAVHGTRILKGCMPLRVEKLPDGQLQVTWVDLASDRKDVGTFDTVLWATGRVPEIGSLNLEKAGVHTNPHTQKILVDAQDATSVPHIYAIGDVAEGRPELTPTAVMAGRLLAQRLCGRSSDLMDYDNVPTTVFTPLEYGCVGLSEEAAVARHGEEGVEVYHAYYKPLEFTVPERDASQCYIKMVCLREPPQLVLGLHFLGPNAGEVTQGFALALKCGASYEQVMRTVGIHPTCAEEVAKLRISKRSG", "length": 487, "header": "tr|A0A286ZJ07-1|A0A5G2RKP4_PIG Computationally mapped isoform of thioredoxin-disulfide reductase (NADPH) OS=Sus scrofa OX=9823 GN=TXNRD2 PE=1 SV=2 CANONICAL=A0A5G2RKP4-1" }, "locus": { "chromosome": "14", "start_pos": 51383262, "end_pos": 51356834, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050511.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050511.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031506.2", "url": "https://www.ensembl.org/id/ENSSSCP00000031506.2" } ] } }, { "isoform_ac": "A0A5G2RKP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4/entry#A0A5G2RKP4-1", "sequence": { "sequence": "MIFCDAFLPPGGAGLVLGALTPALARSSHRLSPLGTYLSSPPLLRCAQAPPGPACSPLPFTQAGQQCYDLLVIGGGSGGLACAKEAAQLGKKVAVVDYVSPSPRGTRWGLGGTCVNVGCIPKKLMHQAALLGGVIRDAPHYGWEVAQPALHSWKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNFKASFVNKHTVCGVLKGGKEILLSAEHIVIATGGRPRYPAHIEGAVEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGLGLDATIMIRSIPLRAFDQQMASLVIEHMAVHGTRILKGCMPLRVEKLPDGQLQVTWVDLASDRKDVGTFDTVLWATGRVPEIGSLNLEKAGVHTNPHTQKILVDAQDATSVPHIYAIGDVAEGRPELTPTAVMAGRLLAQRLCGRSSDLMDYDNVPTTVFTPLEYGCVGLSEEAAVARHGEEGVEVYHAYYKPLEFTVPERDASQCYIKMVCLREPPQLVLGLHFLGPNAGEVTQGFALALKCGASYEQVMRTVGIHPTCAEEVAKLRISKRSG", "length": 541, "header": "tr|A0A5G2RKP4-1|A0A5G2RKP4_PIG Isoform 1 of thioredoxin-disulfide reductase (NADPH) OS=Sus scrofa OX=9823 GN=TXNRD2 PE=1 SV=2 CANONICAL=A0A5G2RKP4-1" }, "locus": { "chromosome": "14", "start_pos": 51383051, "end_pos": 51356834, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090575.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090575.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072727.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072727.2" } ] } }, { "isoform_ac": "F1RHN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4/entry#F1RHN4-1", "sequence": { "sequence": "CLIEWGRGARRCSRGPAVAAGRTAGQQCYDLLVIGGGSGGLACAKEAAQLGKKVAVVDYVSPSPRGTRWGLGGTCVNVGCIPKKLMHQAALLGGVIRDAPHYVLGLKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNFKASFVNKHTVCGVLKGGKEILLSAEHIVIATGGRPRYPAHIEGAVEYGITNVALECAGFLTGLGLDATIMIRSIPLRAFDQQMASLVIEHMAVHGTRILKGCMPLRVEKLPDGQLQVTWVDLASDRKDVGTFDTVLWATGRVPEIGSLNLEKAGVHTNPHTQKILVDAQDATSVPHIYAIGDVAEGRPELTPTAVMAGRLLAQRLCGRSSDLMDYDNVPTTVFTPLEYGCVGLSEEAAVARHGEEGVEVYHAYYKPLEFTVPERDASQCYIKMVCLREPPQLVLGLHFLGPNAGEVTQGFALALKCGASYEQVMRTVGIHPTCAEEVAKLRISKRSG", "length": 474, "header": "tr|F1RHN4-1|A0A5G2RKP4_PIG Computationally mapped isoform of thioredoxin-disulfide reductase (NADPH) OS=Sus scrofa OX=9823 GN=TXNRD2 PE=1 SV=4 CANONICAL=A0A5G2RKP4-1" }, "locus": { "chromosome": "14", "start_pos": 51383250, "end_pos": 51356834, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011092.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011092.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010804.4", "url": "https://www.ensembl.org/id/ENSSSCP00000010804.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZJ07", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJ07" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "thioredoxin-disulfide reductase (NADPH) activity", "id": "GO:0004791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004791", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" } ], "pmid": "" }, { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" } ], "pmid": "" }, { "name": "glutathione-disulfide reductase (NADPH) activity", "id": "GO:0004362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004362", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor", "id": "GO:0016668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016668", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RKP4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 541, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RKP4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RKP4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RKP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" }, { "id": "PF07992", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07992" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAD/NAD(P)-binding", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 402, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RKP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKP4" }, { "id": "PF02852", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02852" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pyridine nucleotide-disulphide oxidoreductase dimerisation", "eco_id": "ECO_0000259", "start_pos": 422, "end_pos": 533, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RN10-1", "uniprot_ac": "A0A5G2RN10", "uniprot_id": "A0A5G2RN10_PIG", "mass": { "chemical_mass": 39090.0, "monoisotopic_mass": 39090.0 }, "refseq": {}, "gene_names": [ { "name": "MAPT", "type": "recommended", "evidence": [ { "id": "A0A5G2RN10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10" } ] } ], "protein_names": [ { "name": "Microtubule-associated protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RN10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MAPT", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10", "locus": { "chromosome": "12", "start_pos": 17095587, "end_pos": 17211373, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017311", "url": "https://www.ensembl.org/id/ENSSSCG00000017311" } ] } } ], "crossref": [ { "id": "A0A5G2RN10", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RN10", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017311", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017311", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002955", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002955", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027324", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027324", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11501:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11501:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00418", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00418", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-264870", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZJ75", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJ75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZJ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJ75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXV0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AAQ4", "url": "https://www.uniprot.org/uniprotkb/A0A287AAQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AAQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AAQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B830", "url": "https://www.uniprot.org/uniprotkb/A0A287B830", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B830-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B830-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RN10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RN10-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RNE3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RNE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRS8", "url": "https://www.uniprot.org/uniprotkb/F1RRS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRS8-1", "url": "https://www.uniprot.org/uniprotkb/F1RRS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPRQEFTVMEDHAQGDYTLLQDHEGDVDHSLKAEEAGIGDTPNLEDQAAGHVTQARMVSKGKDGTGPDDKKTKGADGKPGSKIATPRGAAPPGQKGPANATRIPAKTTPSPKTPPGSGESGKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSAAKSRLQTAPGPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL", "length": 375, "header": "tr|A0A5G2RN10-1|A0A5G2RN10_PIG Isoform 1 of Microtubule-associated protein OS=Sus scrofa OX=9823 GN=MAPT PE=1 SV=2 CANONICAL=A0A5G2RN10-1" }, "isoforms": [ { "isoform_ac": "A0A286ZJ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10/entry#A0A286ZJ75-1", "sequence": { "sequence": "MAEPRQEFTVMEDHAQGDYTLLQDHEGDVDHSLKESPLQTPADDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGEQAAAQPPTEIPEGTTAEEAGIGDTPNLEDQAAGHVTQEEGSVPGQQREAPERPQADELSPQVQTGHGQEASGVSKLPLGEKQPEAAVLAISRLSQLHLSQPPPPPGGPQEPHPEWGPKPGERAQEGLAFLKPISPEYLQMEPESAKVVQESFPREPGHRGGEAMDPGTPGLTGQHVSNMPRAPILPEGPREATYQPLGTEPEDTEGSRHGSELLEHQLLGAVTQEGLPLKGKRGKERLGSQEVDEDRDIDESSPQDSPPSLVSPGLQSPPDQGGPPPQAVSREAPGISSFPAEGAIPLPVDFLFKASAETQVSEPDGPGEGPPAERHDGPPEFMFHVEIKANVQKDQGHPQVDLEGAALPGAPGEEREPLGPSEGEDTKKTDLLEASEKQPAAGLPGKPVSRVPQLKARMVSKGKDGTGPDDKKTKTSTPSSAKTLKNRPCLSPKRPTPGSSDPLIKPSSPAVCPEPSSSPKRVSSVTPRTGGSGAKEMKVKGADGKPGSKIATPRGAAPPGQKGPANATRIPAKTTPSPKTPPGSVTKQVQKKPPPAGAITERGESGKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSAAKSRLQTAPGPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL", "length": 887, "header": "tr|A0A286ZJ75-1|A0A5G2RN10_PIG Computationally mapped isoform of Microtubule-associated protein OS=Sus scrofa OX=9823 GN=MAPT PE=1 SV=3 CANONICAL=A0A5G2RN10-1" }, "locus": { "chromosome": "12", "start_pos": 17150726, "end_pos": 17102072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042873.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042873.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031628.3", "url": "https://www.ensembl.org/id/ENSSSCP00000031628.3" } ] } }, { "isoform_ac": "A0A286ZXV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10/entry#A0A286ZXV0-1", "sequence": { "sequence": "MEPESAKVVQESFPREPGHRGGEAMDPGTPGLTGQHVSNMPRAPILPEGPREATYQPLGTEPEDTEGSRHGSELLEHQLLGAVTQEGLPLKGKRGKERLGSQEVDEDRDIDESSPQDSPPSLVSPGLQSPPDQGGPPPQAVSREAPGISSFPAEGAIPLPVDFLFKASAETQVSEPDGPGEGPPAERHDGPPEFMFHVEIKANVQKDQGHPQVDLEGAALPGAPGEEREPLGPSEGEDTKKTDLLEASEKQPAAGLPGKPVSRVPQLKGLCLELLCSCLATSYTSTPSSAKTLKNRPCLSPKRPTPGSSDPLIKPSSPAVCPEPSSSPKRVSSVTPRTGGSGAKEMKVKGADGKPGSKIATPRGAAPPGQKGPANATRIPAKTTPSPKTPPGSVTKQVQKKPPPAGAITERGESGKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSAAKSRLQTAPGPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL", "length": 667, "header": "tr|A0A286ZXV0-1|A0A5G2RN10_PIG Computationally mapped isoform of Microtubule-associated protein OS=Sus scrofa OX=9823 GN=MAPT PE=1 SV=3 CANONICAL=A0A5G2RN10-1" }, "locus": { "chromosome": "12", "start_pos": 17134786, "end_pos": 17102072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054533.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054533.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036466.3", "url": "https://www.ensembl.org/id/ENSSSCP00000036466.3" } ] } }, { "isoform_ac": "A0A287AAQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10/entry#A0A287AAQ4-1", "sequence": { "sequence": "MAEPRQEFTVMEDHAQGDYTLLQDHEGDVDHSLKESPLQTPADDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGEQAAAQPPTEIPEGTTAEEAGIGDTPNLEDQAAGHVTQASAETQVSEPDGPGEGPPAERHDGPPEFMFHVEIKANVQKDQGHPQVDLEGAALPGAPGEEREPLGPSEGEDTKKTDLLEASEKQPAAGLPGKPVSRVPQLKARMVSKGKDGTGPDDKKTKTSTPSSAKTLKNRPCLSPKRPTPGSSDPLIKPSSPAVCPEPSSSPKRVSSVTPRTGGSGAKEMKVKGADGKPGSKIATPRGAAPPGQKGPANATRIPAKTTPSPKTPPGSVTKQVQKKPPPAGAITERGESGKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSAAKSRLQTAPGPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGARERGDHPTRPSPVVQQCRGRQDPVSKVSS", "length": 648, "header": "tr|A0A287AAQ4-1|A0A5G2RN10_PIG Computationally mapped isoform of Microtubule-associated protein OS=Sus scrofa OX=9823 GN=MAPT PE=1 SV=2 CANONICAL=A0A5G2RN10-1" }, "locus": { "chromosome": "12", "start_pos": 17150726, "end_pos": 17095590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065427.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065427.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041032.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041032.2" } ] } }, { "isoform_ac": "A0A287B830-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10/entry#A0A287B830-1", "sequence": { "sequence": "MAEPRQEFTVMEDHAQGDYTLLQDHEGDVDHSLKESPLQTPADDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGEQAAAQPPTEIPEGTTAEEAGIGDTPNLEDQAAGHVTQEEGSVPGQQREAPERPQADELSPQVQTGHGQEASGVSKLPLGEKQPEAAVLAISRLSQLHLSQPPPPPGGPQEPHPEWGPKPGERAQEGLAFLKPISPEYLQMEPESAKVVQESFPREPGHRGGEAMDPGTPGLTGQHVSNMPRAPILPEGPREATYQPLGTEPEDTEGSRHGSELLEHQLLGAVTQEGLPLKGKRGKERLGSQEVDEDRDIDESSPQDSPPSLVSPGLQSPPDQGGPPPQAVSREAPGISSFPAEGAIPLPVDFLFKASAETQVSEPDGPGEGPPAERHDGPPEFMFHVEIKANVQKDQGHPQVDLEGAALPGAPGEEREPLGPSEGEDTKKTDLLEASEKQPAAGLPGKPVSRVPQLKARMVSKGKDGTGPDDKKTKTSTPSSAKTLKNRPCLSPKRPTPGSSDPLIKPSSPAVCPEPSSSPKRVSSVTPRTGGSGAKEMKVKGADGKPGSKIATPRGAAPPGQKGPANATRIPAKTTPSPKTPPGSGESGKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSAAKSRLQTAPGPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL", "length": 869, "header": "tr|A0A287B830-1|A0A5G2RN10_PIG Computationally mapped isoform of Microtubule-associated protein OS=Sus scrofa OX=9823 GN=MAPT PE=1 SV=2 CANONICAL=A0A5G2RN10-1" }, "locus": { "chromosome": "12", "start_pos": 17150726, "end_pos": 17102072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044399.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044399.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052234.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052234.2" } ] } }, { "isoform_ac": "A0A5G2RN10-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10/entry#A0A5G2RN10-1", "sequence": { "sequence": "MAEPRQEFTVMEDHAQGDYTLLQDHEGDVDHSLKAEEAGIGDTPNLEDQAAGHVTQARMVSKGKDGTGPDDKKTKGADGKPGSKIATPRGAAPPGQKGPANATRIPAKTTPSPKTPPGSGESGKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSAAKSRLQTAPGPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL", "length": 375, "header": "tr|A0A5G2RN10-1|A0A5G2RN10_PIG Isoform 1 of Microtubule-associated protein OS=Sus scrofa OX=9823 GN=MAPT PE=1 SV=2 CANONICAL=A0A5G2RN10-1" }, "locus": { "chromosome": "12", "start_pos": 17150726, "end_pos": 17102072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082032.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082032.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074115.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074115.2" } ] } }, { "isoform_ac": "A0A5G2RNE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10/entry#A0A5G2RNE3-1", "sequence": { "sequence": "MAEPRQEFTVMEDHAQGDYTLLQDHEGDVDHSLKESPLQTPADDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGEQAAAQPPTEIPEGTTAEEAGIGDTPNLEDQAAGHVTQASAETQVSEPDGPGEGPPAERHDGPPEFMFHVEIKANVQKDQGHPQVDLEGAALPGAPGEEREPLGPSEGEDTKKTDLLEASEKQPAAGLPGKPVSRVPQLKARMVSKGKDGTGPDDKKTKTSTPSSAKTLKNRPCLSPKRPTPGSSDPLIKPSSPAVCPEPSSSPKRVSSVTPRTGGSGAKEMKVKGADGKPGSKIATPRGAAPPGQKGPANATRIPAKTTPSPKTPPGSVTKQVQKKPPPAGAITERGESGKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSAAKSRLQTAPGPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQAAPHRSVNRLIT", "length": 629, "header": "tr|A0A5G2RNE3-1|A0A5G2RNE3_PIG Computationally mapped isoform of Microtubule-associated protein OS=Sus scrofa OX=9823 GN=MAPT PE=1 SV=1 CANONICAL=A0A5G2RN10-1" }, "locus": { "chromosome": "12", "start_pos": 17150726, "end_pos": 17101932, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067970.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067970.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074355.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074355.1" } ] } }, { "isoform_ac": "F1RRS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10/entry#F1RRS8-1", "sequence": { "sequence": "MAEPRQEFTVMEDHAQGDYTLLQDHEGDVDHSLKESPLQTPADDGSEEPGSETSDAKSTPTAEGDSWWFPDVTAPLVDEGAPGEQAAAQPPTEIPEGTTAEEAGIGDTPNLEDQAAGHVTQARMVSKGKDGTGPDDKKTKGADGKPGSKIATPRGAAPPGQKGPANATRIPAKTTPSPKTPPGSGESGKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSAAKSRLQTAPGPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL", "length": 440, "header": "tr|F1RRS8-1|A0A5G2RN10_PIG Computationally mapped isoform of Microtubule-associated protein OS=Sus scrofa OX=9823 GN=MAPT PE=1 SV=4 CANONICAL=A0A5G2RN10-1" }, "locus": { "chromosome": "12", "start_pos": 17150726, "end_pos": 17102072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080222.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080222.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066289.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066289.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 139, "start_aa": "Thr", "end_pos": 139, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr139", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 151, "start_aa": "Thr", "end_pos": 151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZJ75", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJ75" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-264870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264870", "resource": "Reactome", "description": "Caspase-mediated cleavage of cytoskeletal proteins" }, { "id": "R-SSC-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RN10-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 375, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RN10-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RN10" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 139, 151 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 344, "end_pos": 346 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RMX2-1", "uniprot_ac": "A0A5G2RMX2", "uniprot_id": "A0A5G2RMX2_PIG", "mass": { "chemical_mass": 22931.0, "monoisotopic_mass": 22931.0 }, "refseq": {}, "gene_names": [ { "name": "RAB7A", "type": "recommended", "evidence": [ { "id": "A0A5G2RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab-7a", "type": "recommended", "evidence": [ { "id": "A0A5G2RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RAB7A", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2", "locus": { "chromosome": "13", "start_pos": 71777424, "end_pos": 71852694, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011615", "url": "https://www.ensembl.org/id/ENSSSCG00000011615" } ] } } ], "crossref": [ { "id": "A0A5G2RMX2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RMX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011615", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011615", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01862", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01862", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100622795", "url": "https://www.ncbi.nlm.nih.gov/gene/100622795", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47981:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47981:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2132295", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013407", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZMP2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZMP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZMP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZMP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZP69", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZP69-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BQX8", "url": "https://www.uniprot.org/uniprotkb/A0A287BQX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BQX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BQX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R382", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R382", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R382-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R382-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMS7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SPG0", "url": "https://www.uniprot.org/uniprotkb/F1SPG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SPG0-1", "url": "https://www.uniprot.org/uniprotkb/F1SPG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQVGLSPCLSFPYPSLLAVIIWDSNDTFC", "length": 203, "header": "tr|A0A5G2RMX2-1|A0A5G2RMX2_PIG Isoform 1 of Ras-related protein Rab-7a OS=Sus scrofa OX=9823 GN=RAB7A PE=1 SV=1 CANONICAL=A0A5G2RMX2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZMP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2/entry#A0A286ZMP2-1", "sequence": { "sequence": "MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPKPAVAEATVSRAQSPSRSKNTLRPSTTRPPSPESSLLSSCQEKPHPTTPSPCTHTHTHTHTHIHT", "length": 252, "header": "tr|A0A286ZMP2-1|A0A5G2RMX2_PIG Computationally mapped isoform of Ras-related protein Rab-7a OS=Sus scrofa OX=9823 GN=RAB7A PE=1 SV=1 CANONICAL=A0A5G2RMX2-1" }, "locus": { "chromosome": "13", "start_pos": 71797630, "end_pos": 71778561, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053991.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053991.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032899.2", "url": "https://www.ensembl.org/id/ENSSSCP00000032899.2" } ] } }, { "isoform_ac": "A0A286ZP69-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2/entry#A0A286ZP69-1", "sequence": { "sequence": "MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPAVAEATVSRAQSPSRSKNTLRPSTTRPPSPESSLLSSCQEKPHPTTPSPCTHTHTHTHTHIHT", "length": 252, "header": "tr|A0A286ZP69-1|A0A5G2RMX2_PIG Computationally mapped isoform of Ras-related protein Rab-7a OS=Sus scrofa OX=9823 GN=RAB7A PE=1 SV=2 CANONICAL=A0A5G2RMX2-1" }, "locus": { "chromosome": "13", "start_pos": 71797630, "end_pos": 71778561, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043009.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043009.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033254.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033254.2" } ] } }, { "isoform_ac": "A0A287BQX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2/entry#A0A287BQX8-1", "sequence": { "sequence": "WRKWERSPSLGHKARGGGGGGAGSLDRLRIPLQSELGLSSALVFPPSPPRQTPTDTPGPEPSGAAAIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKPPAETCSC", "length": 213, "header": "tr|A0A287BQX8-1|A0A5G2RMX2_PIG Computationally mapped isoform of Ras-related protein Rab-7a OS=Sus scrofa OX=9823 GN=RAB7A PE=1 SV=2 CANONICAL=A0A5G2RMX2-1" }, "locus": { "chromosome": "13", "start_pos": 71852669, "end_pos": 71778742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047733.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047733.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058849.3", "url": "https://www.ensembl.org/id/ENSSSCP00000058849.3" } ] } }, { "isoform_ac": "A0A5G2QNS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2/entry#A0A5G2QNS1-1", "sequence": { "sequence": "MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQGTQPDRNGSSLLAWPSTEAQTAAFWCLIPAPRRPSMWSKPSRRSLGTR", "length": 108, "header": "tr|A0A5G2QNS1-1|A0A5G2QNS1_PIG Computationally mapped isoform of Ras-related protein Rab-7a OS=Sus scrofa OX=9823 GN=RAB7A PE=1 SV=1 CANONICAL=A0A5G2RMX2-1" }, "locus": { "chromosome": "13", "start_pos": 71797630, "end_pos": 71782284, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073226.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073226.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065705.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065705.1" } ] } }, { "isoform_ac": "A0A5G2R382-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2/entry#A0A5G2R382-1", "sequence": { "sequence": "MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQETEVELYNEFPEPIKLDKNDRAKPPAETCSC", "length": 91, "header": "tr|A0A5G2R382-1|A0A5G2RMX2_PIG Computationally mapped isoform of Ras-related protein Rab-7a OS=Sus scrofa OX=9823 GN=RAB7A PE=1 SV=1 CANONICAL=A0A5G2RMX2-1" }, "locus": { "chromosome": "13", "start_pos": 71797630, "end_pos": 71778742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085904.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085904.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068652.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068652.1" } ] } }, { "isoform_ac": "A0A5G2RMS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2/entry#A0A5G2RMS7-1", "sequence": { "sequence": "MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKPPAETCSC", "length": 134, "header": "tr|A0A5G2RMS7-1|A0A5G2RMS7_PIG Computationally mapped isoform of Ras-related protein Rab-7a OS=Sus scrofa OX=9823 GN=RAB7A PE=1 SV=1 CANONICAL=A0A5G2RMX2-1" }, "locus": { "chromosome": "13", "start_pos": 71797630, "end_pos": 71778742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071892.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071892.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073959.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073959.1" } ] } }, { "isoform_ac": "A0A5G2RMX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2/entry#A0A5G2RMX2-1", "sequence": { "sequence": "MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQVGLSPCLSFPYPSLLAVIIWDSNDTFC", "length": 203, "header": "tr|A0A5G2RMX2-1|A0A5G2RMX2_PIG Isoform 1 of Ras-related protein Rab-7a OS=Sus scrofa OX=9823 GN=RAB7A PE=1 SV=1 CANONICAL=A0A5G2RMX2-1" }, "locus": { "chromosome": "13", "start_pos": 71797630, "end_pos": 71782195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089194.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089194.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074035.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074035.1" } ] } }, { "isoform_ac": "A0A8W4FGK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2/entry#A0A8W4FGK5-1", "sequence": { "sequence": "ITKKKKKPHISVSLVGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQVGLSPCLSFPYPSLLAVIIWDSNDTFC", "length": 201, "header": "tr|A0A8W4FGK5-1|A0A5G2RMX2_PIG Computationally mapped isoform of Ras-related protein Rab-7a OS=Sus scrofa OX=9823 GN=RAB7A PE=1 SV=1 CANONICAL=A0A5G2RMX2-1" }, "locus": { "chromosome": "13", "start_pos": 71795473, "end_pos": 71782195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106658.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106658.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078566.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078566.1" } ] } }, { "isoform_ac": "F1SPG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2/entry#F1SPG0-1", "sequence": { "sequence": "MSDAGEVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKPPAETCSC", "length": 195, "header": "tr|F1SPG0-1|F1SPG0_PIG Computationally mapped isoform of Ras-related protein Rab-7a OS=Sus scrofa OX=9823 GN=RAB7A PE=1 SV=3 CANONICAL=A0A5G2RMX2-1" }, "locus": { "chromosome": "13", "start_pos": 71795026, "end_pos": 71778742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012712.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012712.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012378.3", "url": "https://www.ensembl.org/id/ENSSSCP00000012378.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZMP2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZMP2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2132295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "resource": "Reactome", "description": "MHC class II antigen presentation" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-8854214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854214", "resource": "Reactome", "description": "TBC/RABGAPs" }, { "id": "R-SSC-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-SSC-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-SSC-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-SSC-9013407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013407", "resource": "Reactome", "description": "RHOH GTPase cycle" }, { "id": "R-SSC-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-SSC-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-SSC-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 13, "go_terms": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "melanosome membrane", "id": "GO:0033162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033162", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "retromer complex", "id": "GO:0030904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "retromer complex binding", "id": "GO:1905394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905394", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "sterol sensor activity", "id": "GO:0032935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032935", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 22, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "phagosome-lysosome fusion", "id": "GO:0090385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090385", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "phagosome acidification", "id": "GO:0090383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090383", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "early endosome to late endosome transport", "id": "GO:0045022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045022", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "protein targeting to lysosome", "id": "GO:0006622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006622", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "positive regulation of exosomal secretion", "id": "GO:1903543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903543", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "protein to membrane docking", "id": "GO:0022615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "negative regulation of exosomal secretion", "id": "GO:1903542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903542", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "endosome to plasma membrane protein transport", "id": "GO:0099638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099638", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "viral release from host cell", "id": "GO:0019076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019076", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "positive regulation of viral process", "id": "GO:0048524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "epidermal growth factor catabolic process", "id": "GO:0007174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007174", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "lipophagy", "id": "GO:0061724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061724", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" }, { "name": "lysosome to ER cholesterol transport", "id": "GO:0090120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090120", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMX2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RMX2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 203, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RMX2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RMX2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RN08-1", "uniprot_ac": "A0A5G2RN08", "uniprot_id": "A0A5G2RN08_PIG", "mass": { "chemical_mass": 58543.0, "monoisotopic_mass": 58543.0 }, "refseq": { "ac": "XP_003358415", "name": "xylulose kinase isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358415" }, "gene_names": [ { "name": "XYLB", "type": "recommended", "evidence": [ { "id": "A0A5G2RN08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08" } ] }, { "name": "XYLB", "type": "synonym", "evidence": [ { "id": "XP_003358415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358415" } ] } ], "protein_names": [ { "name": "Xylulose kinase", "type": "recommended", "evidence": [ { "id": "A0A5G2RN08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.17", "type": "synonym", "evidence": [ { "id": "A0A5G2RN08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08/entry#names_and_taxonomy" } ] }, { "name": "xylulose kinase isoform X3", "type": "synonym", "evidence": [ { "id": "XP_003358415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358415" } ] } ], "function": [ { "annotation": "Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZNC6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNC6#function" }, { "database": "UniProtKB", "id": "RU367058", "url": "https://www.uniprot.org/uniprotkb/RU367058#function" }, { "database": "UniProtKB", "id": "A0A287A3Y3", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Y3#function" }, { "database": "UniProtKB", "id": "A0A5G2QZP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP7#function" }, { "database": "UniProtKB", "id": "A0A5G2RN08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08#function" }, { "database": "UniProtKB", "id": "ARBA00003260", "url": "https://www.uniprot.org/uniprotkb/ARBA00003260#function" }, { "database": "UniProtKB", "id": "F1RRB3", "url": "https://www.uniprot.org/uniprotkb/F1RRB3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "XYLB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08", "locus": { "chromosome": "13", "start_pos": 23225951, "end_pos": 23173939, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011254", "url": "https://www.ensembl.org/id/ENSSSCG00000011254" } ] } } ], "crossref": [ { "id": "A0A5G2RN08", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RN08", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011254", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011254", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07776", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07776", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100628009", "url": "https://www.ncbi.nlm.nih.gov/gene/100628009", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100628009", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100628009", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NSCALGG", "url": "https://omabrowser.org/oma/group/NSCALGG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10196:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10196:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5661270", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5661270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003358415", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358415", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10964", "url": "https://www.rhea-db.org/rhea/10964", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZNC6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZNC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3Y3", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZP7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RN08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RN08-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRB3", "url": "https://www.uniprot.org/uniprotkb/F1RRB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRB3-1", "url": "https://www.uniprot.org/uniprotkb/F1RRB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEHSARHCCLGWDFSTQQVKVVAVDAELNVFYEDSVHFDRDLPEFRTQGGVHVHEDGLTVTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSVYWKAGANQVLMSLTPDLLLREQLQACFSISDSPVWMDSSTTAQCRQLEATVGGAQALSSLTGSRAYERFTGNQIAKIYQKNPEAYSRTERISLVSSFAASLFLGSYSPIDHSDGSGMNLLQIQDKVWSQACLGACAPGLEEKLGQPVPSCSVVGAISSYFVQRYGFPAGCKVVAFTGDNPASLAGMRLEEGDIAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDPQHYMALLCFKNGSLMREKIRDESASRSWSEFSKALRSTELGNGGNLGFYFDVMEITPEIIGRHRFNAENHEVSAFPWDVEIRALIEGQFMAKKIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVIDTANSACVGSAYRAFHGLAAGTNMPFSEVVKLAPNPRLAATPTPGAFQVYEALLQRYAVLEQRVLTQTRRPSE", "length": 536, "header": "tr|A0A5G2RN08-1|A0A5G2RN08_PIG Isoform 1 of Xylulose kinase OS=Sus scrofa OX=9823 GN=XYLB PE=1 SV=1 CANONICAL=A0A5G2RN08-1" }, "isoforms": [ { "isoform_ac": "A0A286ZNC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08/entry#A0A286ZNC6-1", "sequence": { "sequence": "MAEHSARHCCLGWDFSTQQVKVVAVDAELNVFYEDSVHFDRDLPEFRTQGGVHVHEDGLTVTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSVYWKAGANQVLMSLTPDLLLREQLQACFSISDSPVWMDSSTTAQCRQLEATVGGAQALSSLTGSRAYERFTGNQIAKIYQKNPEAYSRTERISLVSSFAASLFLGSYSPIDHSDGSGMNLLQIQDKVWSQACLGACAPGLEEKLGQPVPSCSVVVSLGTSDTLFLWLQEPMPALEGHIFCNPVDPQHYMALLCFKNGSLMREKIRDESASRSWSEFSKALRSTELGNGGNLGFYFDVMEITPEIIGRHRFNAENHEVSAFPWDVEIRALIEGQFMAKKIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVIDTANSACVGSAYRAFHGLAAGTNMPFSEVVKLAPNPRLAATPTPGAFQVYEALLQRYAVLEQRVLTQTRRPSE", "length": 495, "header": "tr|A0A286ZNC6-1|A0A5G2RN08_PIG Computationally mapped isoform of Xylulose kinase OS=Sus scrofa OX=9823 GN=XYLB PE=1 SV=1 CANONICAL=A0A5G2RN08-1" }, "locus": { "chromosome": "13", "start_pos": 23221821, "end_pos": 23174020, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051999.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051999.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033129.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033129.2" } ] } }, { "isoform_ac": "A0A287A3Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08/entry#A0A287A3Y3-1", "sequence": { "sequence": "MAEHSARHCCLGWDFSTQQVKVVAVDAELNVFYEDSVHFDRDLPEFRTQGGVHVHEDGLTVTSPVLMWVQQHGSVYWKAGANQVLMSLTPDLLLREQLQACFSISDSPVWMDSSTTAQCRQLEATVGGAQALSSLTGSRAYERFTGNQIAKIYQKNPEAYSRTERISLVSSFAASLFLGSYSPIDHSDGSGMNLLQIQDKVWSQACLGACAPGLEEKLGQPVPSCSVVGAISSYFVQRYGFPAGCKVVAFTGDNPASLAGMRLEEGDIAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDPQHYMALLCFKNGSLMREKIRDESASRSWSEFSKALRSTELGNGGNLGFYFDVMEITPEIIGRHRFNAENHEVSAFPWDVEIRALIEGQFMAKKIHAEGLGYRVSLAAGTNMPFSEVVKLAPNPRLAATPTPGAFQVYEALLQRYAVLEQRVLTQTRRPSE", "length": 460, "header": "tr|A0A287A3Y3-1|A0A5G2RN08_PIG Computationally mapped isoform of Xylulose kinase OS=Sus scrofa OX=9823 GN=XYLB PE=1 SV=2 CANONICAL=A0A5G2RN08-1" }, "locus": { "chromosome": "13", "start_pos": 23221821, "end_pos": 23174020, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040460.2", "url": "https://www.ensembl.org/id/ENSSSCT00000040460.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038461.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038461.2" } ] } }, { "isoform_ac": "A0A5G2QZP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08/entry#A0A5G2QZP7-1", "sequence": { "sequence": "MAEHSARHCCLGWDFSTQQVKVVAVDAELNVFYEDSVHFDRDLPEFRTQGGVHVHEDGLTVTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSVYWKAGANQVLMSLTPDLLLREQLQACFSISDSPVWMDSSTTAQCRQLEATVGGAQALSSLTGSRAYERFTGNQIAKIYQKNPEAYSRTESVSKISVSCFLPSLGSGMNLLQIQDKVWSQACLGACAPGLEEKLGQPVPSCSVVGAISSYFVQRYGFPAGCKVVAFTGDNPASLAGMRLEEGDIAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDPQHYMALLCFKNGSLMREKIRDESASRSWSEFSKALRSTELGNGGNLGFYFDVMEITPEIIGRHRFNAENHEVSAFPWDVEIRALIEGQFMAKKIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVIDTANSACVGSAYRAFHGLAAGTNMPFSEVVKLAPNPRLAATPTPGAFQVYEALLQRYAVLEQRVLTQTRRPSE", "length": 526, "header": "tr|A0A5G2QZP7-1|A0A5G2RN08_PIG Computationally mapped isoform of Xylulose kinase OS=Sus scrofa OX=9823 GN=XYLB PE=1 SV=1 CANONICAL=A0A5G2RN08-1" }, "locus": { "chromosome": "13", "start_pos": 23221821, "end_pos": 23174020, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077708.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077708.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070368.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070368.1" } ] } }, { "isoform_ac": "A0A5G2RN08-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08/entry#A0A5G2RN08-1", "sequence": { "sequence": "MAEHSARHCCLGWDFSTQQVKVVAVDAELNVFYEDSVHFDRDLPEFRTQGGVHVHEDGLTVTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSVYWKAGANQVLMSLTPDLLLREQLQACFSISDSPVWMDSSTTAQCRQLEATVGGAQALSSLTGSRAYERFTGNQIAKIYQKNPEAYSRTERISLVSSFAASLFLGSYSPIDHSDGSGMNLLQIQDKVWSQACLGACAPGLEEKLGQPVPSCSVVGAISSYFVQRYGFPAGCKVVAFTGDNPASLAGMRLEEGDIAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDPQHYMALLCFKNGSLMREKIRDESASRSWSEFSKALRSTELGNGGNLGFYFDVMEITPEIIGRHRFNAENHEVSAFPWDVEIRALIEGQFMAKKIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVIDTANSACVGSAYRAFHGLAAGTNMPFSEVVKLAPNPRLAATPTPGAFQVYEALLQRYAVLEQRVLTQTRRPSE", "length": 536, "header": "tr|A0A5G2RN08-1|A0A5G2RN08_PIG Isoform 1 of Xylulose kinase OS=Sus scrofa OX=9823 GN=XYLB PE=1 SV=1 CANONICAL=A0A5G2RN08-1" }, "locus": { "chromosome": "13", "start_pos": 23221821, "end_pos": 23174020, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068182.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068182.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074110.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074110.1" } ] } }, { "isoform_ac": "F1RRB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08/entry#F1RRB3-1", "sequence": { "sequence": "MAEHSARHCCLGWDFSTQQVKVVAVDAELNVFYEDSVHFDRDLPEFRTQGGVHVHEDGLTVTSPVLMWVQQHGSVYWKAGANQVLMSLTPDLLLREQLQACFSISDSPVWMDSSTTAQCRQLEATVGGAQALSSLTGSRAYERFTGNQIAKIYQKNPEAYSRTERISLVSSFAASLFLGSYSPIDHSDGSGMNLLQIQDKVWSQACLGACAPGLEEKLGQPVPSCSVVGAISSYFVQRYGFPAGCKVVAFTGDNPASLAGMRLEEGDIAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDPQHYMALLCFKNGSLMREKIRDESASRSWSEFSKALRSTELGNGGNLGFYFDVMEITPEIIGRHRFNAENHEVSAFPWDVEIRALIEGQFMAKKIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVIDTANSACVGSAYRAFHGLAAGTNMPFSEVVKLAPNPRLAATPTPGAFQVYEALLQRYAVLEQRVLTQTRRPSE", "length": 509, "header": "tr|F1RRB3-1|A0A5G2RN08_PIG Computationally mapped isoform of Xylulose kinase OS=Sus scrofa OX=9823 GN=XYLB PE=1 SV=3 CANONICAL=A0A5G2RN08-1" }, "locus": { "chromosome": "13", "start_pos": 23221821, "end_pos": 23174020, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012321.4", "url": "https://www.ensembl.org/id/ENSSSCT00000012321.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011999.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011999.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 506, "start_aa": "Thr", "end_pos": 506, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr506", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZNC6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNC6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100628009", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100628009", "resource": "KEGG Pathway" }, { "id": "R-SSC-5661270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5661270", "resource": "Reactome", "description": "Formation of xylulose-5-phosphate" } ], "orthologs": [ { "uniprot_canonical_ac": "O75191-1", "protein_name": "Xylulose kinase", "gene_name": "XYLB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEHAPRRCCLGWDFSTQQVKVVAVDAELNVFYEESVHFDRDLPEFGTQGGVHVHKDGLTVTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSIYWKAGAQQALTSLSPDLRLHQQLQDCFSISDCPVWMDSSTTAQCRQLEAAVGGAQALSCLTGSRAYERFTGNQIAKIYQQNPEAYSHTERISLVSSFAASLFLGSYSPIDYSDGSGMNLLQIQDKVWSQACLGACAPHLEEKLSPPVPSCSVVGAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDIAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDSQHYMALLCFKNGSLMREKIRNESVSRSWSDFSKALQSTEMGNGGNLGFYFDVMEITPEIIGRHRFNTENHKVAAFPGDVEVRALIEGQFMAKRIHAEGLGYRVMSKTKILATGGASHNREILQVLADVFDAPVYVIDTANSACVGSAYRAFHGLAGGTDVPFSEVVKLAPNPRLAATPSPGASQVYEALLPQYAKLEQRILSQTRGPPE", "length": 536 }, "evidence": [ { "id": "A0A5G2RN08", "url": "https://omabrowser.org/oma/group/A0A5G2RN08/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P42826-1", "protein_name": "Xylulose kinase", "gene_name": "XKS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLCSVIQRQTREVSNTMSLDSYYLGFDLSTQQLKCLAINQDLKIVHSETVEFEKDLPHYHTKKGVYIHGDTIECPVAMWLEALDLVLSKYREAKFPLNKVMAVSGSCQQHGSVYWSSQAESLLEQLNKKPEKDLLHYVSSVAFARQTAPNWQDHSTAKQCQEFEECIGGPEKMAQLTGSRAHFRFTGPQILKIAQLEPEAYEKTKTISLVSNFLTSILVGHLVELEEADACGMNLYDIRERKFSDELLHLIDSSSKDKTIRQKLMRAPMKNLIAGTICKYFIEKYGFNTNCKVSPMTGDNLATICSLPLRKNDVLVSLGTSTTVLLVTDKYHPSPNYHLFIHPTLPNHYMGMICYCNGSLARERIRDELNKERENNYEKTNDWTLFNQAVLDDSESSENELGVYFPLGEIVPSVKAINKRVIFNPKTGMIEREVAKFKDKRHDAKNIVESQALSCRVRISPLLSDSNASSQQRLNEDTIVKFDYDESPLRDYLNKRPERTFFVGGASKNDAIVKKFAQVIGATKGNFRLETPNSCALGGCYKAMWSLLYDSNKIAVPFDKFLNDNFPWHVMESISDVDNENWDRYNSKIVPLSELEKTLI", "length": 600 }, "evidence": [ { "id": "A0A5G2RN08", "url": "https://omabrowser.org/oma/group/A0A5G2RN08/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3MIF4-1", "protein_name": "Xylulose kinase", "gene_name": "Xylb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAERAGRRCCLGWDFSTQQVKVVAVDAELNVFYEDSVHFDRDLPEFGTQGGVHVHKDRLTVTSPVLMWVQALDLILEKMKASGFDFSQVLALSGAGQQHGSVYWKTGASLALSSLSPALLLHQQLQACFSVSDCPIWMDSSTTAQCHQLEAAVGGAQALSCLTGSRAYERFTGNQISKIFQKNPEAYSNSERISLVSSFAASLFLGRYSPIDYSDGSGMNLLQIQEKVWSQACLDACAPHLKEKLGSPVPSCSVVGAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDVAVSLGTSDTLFLWLQKPMPALEGHIFCNPVDARQYMALLCFKNGSLMREKIRDESASCSWNKFSKALQSTEMGNNGNLGFYFDVMEITPEIIGCHRFNADNMEVSAFPGDVEIRALVEGQFMAKRIHAEGLGYRIMPKTKILATGGASHNKDILQVLADVFGAPVYVIDTTSSACVGSAYRAFHGLAGGTGVAFSEVVKSAPQPSLAATPNPGASQVYAALLPRYAELEQRILSKARGPLE", "length": 536 }, "evidence": [ { "id": "A0A5G2RN08", "url": "https://omabrowser.org/oma/group/A0A5G2RN08/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TNA1-1", "protein_name": "Xylulose kinase", "gene_name": "Xylb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDARTHRRAAGTPRALAERAGRRCCLGWDFSTQQVKVVAVDAELNVFYEDSVHFDRDLPEFGTQGGVHVHKDRLTVTSPVLMWVQALDLILGKMKSSGFDFSQVLALSGAGQQHGSVYWKTGASLALSSLSPALPLHQQLQSCFSISDCPIWMDSSTTAQCHQLEAAVGGAQALSCLTGSRAYERFTGNQIAKLFQKNPEAYSHSERISLVSSFAASLFLGGYSPIDYSDGSGMNLLQIQEKVWSQACLDVCAPHLEEKLGSPVPSCSVVGTISSYYVQRYGFPPGCKVVAFSGDNPASLAGMRLEEGDIAVSLGTSDTLFLWLQKPMPALEGHIFCNPVDPQHYMALLCFKNGSLMREKIRDESASCSWNKFSKALKSTAMGNNGNLGFYFDVMEITPEIIGRHRFNAENMEVSAFPGDVEIRALIEGQFMAKRIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVIDTTSSACVGSAYRAFHGLAGGTGVAFSEVVKSAPQPSLAATPNPGASQVYAALLPRYSALEQRILSTAQRPLE", "length": 551 }, "evidence": [ { "id": "A0A5G2RN08", "url": "https://omabrowser.org/oma/group/A0A5G2RN08/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q949W8-1", "protein_name": "Xylulose kinase 2", "gene_name": "XK2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADLSLPPDSLFLGFDSSTQSMKATVLDSNLNIIKTELVHFDSDLPQYKTKDGVYRDTTVNGRIVSPTLMWVEAFDLILQKLSNANFDFAKVIAVSGSGQQHGSVYWSKGSSEVLRSLDSKRSLKEQLENAFSVKESPIWMDSSTTLQCKEIENAVGGAMELSKITGSRAYERFTGPQIRKLFMTQGEVYKSTERISLVSSFMASLLVGDYACIDETDAAGMNLMDIEKRCWSKAALEATATGLEEKLGKLAPAYATAGSISQYFVQRFGFEKNCVVVQWSGDNPNSLAGLTLSTPGDLAISLGTSDTVFGITKELQPSLEGHVLPNPVDPESYMVMLVYKNASLTREEIRDRCAEGSWDVFNKYLQQTQPLNNGKLGFYYTENEILPPLPVGSHRYILENFSGESLEGVKEQEVGEFDPPSEVRALIEGQFLSKRAHTERFGMPSPPLRIIATGGASANENILSLISAIFGCDVYTVQRPDSASLGAALRAAHGWLCNKKGSFVPISNLYEGKLETTSLNCKLKVKAGDANIASTYGLLMKKRMEIENKLVEKLGHF", "length": 558 }, "evidence": [ { "id": "A0A5G2RN08", "url": "https://omabrowser.org/oma/group/A0A5G2RN08/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VEQ0-1", "protein_name": "Xylulose kinase", "gene_name": "Dmel\\CG3534", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGPPKQLKRTFLGFDLSTQKLKAVLLGSSLEVVAAAEVKFDTDLPEFRTTGGANAGSIKNEYFVQPVMWVKAMDIVLDRLVMQQADLSTVAAISGSGQQHGSLYWSKHGINTLQNLDSEKFLHAQIDDSAFVVNRTPIWMDATTTKQCLEMEMAVGGKLNMVELTGSKCYERFTGPQIRKIYQQRCHAYEEANRISLVSSFISSLFLGSVAPIDFSDGSGMNLLDIRKKNWSKECLNVCAPDLDKRLDIPVSPNSILGNVSPYFVERFSFSPDCKVAASTGDNPSALSGMLVGSSWLTISMGTSDTLMMSLKEPLNWEEGHILCHPTETEEFMGLLCFRNASLVREEMNKKTTGGDWDKFNEYLDSTPRGNFGNMAVHFNDMEIIPKAQGILRWNREMDPSSPDAARGVIKFSSPQIEIRALVEGQMLHHRAVAEDLGYKFGPETQILVTGGASVNKSILQTIADVFNAPVHIQDEGFEAALLGAAYRSAYALYLQEAGDGVTPLCYRDYILSLTSNKLSLVCEPHKDSEEIYAPMLQRYREMARVLSNPNT", "length": 552 }, "evidence": [ { "id": "A0A5G2RN08", "url": "https://omabrowser.org/oma/group/A0A5G2RN08/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "xylulose metabolic process", "id": "GO:0005997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005997", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08" } ], "pmid": "" }, { "name": "D-xylose metabolic process", "id": "GO:0042732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042732", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08" } ], "pmid": "" }, { "name": "D-xylulokinase activity", "id": "GO:0004856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10964", "name": "", "equation": "D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10964", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10964" } ] }, { "id": "R-SSC-5662466", "name": "XYLB phosphorylates D-xylulose", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-5661281" ], "output_participant_list": [ "R-ALL-29790" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5662466", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5662466" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29790", "participant_name": "XY5P [cytosol]", "crossref": [ { "id": "ZINC000030320708", "database": "ZINC", "url": "" }, { "id": "C00231", "database": "COMPOUND", "url": "" }, { "id": "57737", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-5661281", "participant_name": "D-xylulose [cytosol]", "crossref": [ { "id": "17140", "database": "ChEBI", "url": "" }, { "id": "C00310", "database": "COMPOUND", "url": "" }, { "id": "ZINC000100028356", "database": "ZINC", "url": "" }, { "id": "HMDB0001644", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RN08-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 536, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RN08-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RN08" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RN08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08" }, { "id": "PF02782", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carbohydrate kinase FGGY C-terminal", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 479, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RN08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN08" }, { "id": "PF00370", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00370" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carbohydrate kinase FGGY N-terminal", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 287, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 506 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 338, "end_pos": 340 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SIV5-1", "uniprot_ac": "A0A4X1SIV5", "uniprot_id": "A0A4X1SIV5_PIG", "mass": { "chemical_mass": 39167.0, "monoisotopic_mass": 39167.0 }, "refseq": { "ac": "XP_005666027", "name": "gastricsin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666027" }, "gene_names": [ { "name": "PGC", "type": "recommended", "evidence": [ { "id": "A0A4X1SIV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5" } ] }, { "name": "PGC", "type": "synonym", "evidence": [ { "id": "XP_005666027", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666027" } ] } ], "protein_names": [ { "name": "Gastricsin", "type": "recommended", "evidence": [ { "id": "A0A4X1SIV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5/entry#names_and_taxonomy" } ] }, { "name": "3.4.23.3", "type": "synonym", "evidence": [ { "id": "A0A4X1SIV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5/entry#names_and_taxonomy" } ] }, { "name": "gastricsin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005666027", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666027" } ] } ], "function": [ { "annotation": "Hydrolyzes a variety of proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP41", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP41#function" }, { "database": "UniProtKB", "id": "ARBA00023749", "url": "https://www.uniprot.org/uniprotkb/ARBA00023749#function" }, { "database": "UniProtKB", "id": "A0A4X1SIV5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIV5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PGC", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5", "locus": { "chromosome": "7", "start_pos": 36922271, "end_pos": 36951349, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001625", "url": "https://www.ensembl.org/id/ENSSSCG00000001625" } ] } } ], "crossref": [ { "id": "A0A4X1SIV5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SIV5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001625", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001625", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100521201", "url": "https://www.ncbi.nlm.nih.gov/gene/100521201", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521201", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521201", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSGEIYW", "url": "https://omabrowser.org/oma/group/YSGEIYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZP41", "url": "https://www.orthodb.org/?gene=A0A286ZP41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SIV5", "url": "https://www.orthodb.org/?gene=A0A4X1SIV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47966:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47966:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005666027", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666027", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZP41", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZP41-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SIV5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKEKGLLEEFLKTHKYDPAQRYRFGDFSVALEPMAYLEAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCKSLACTTHARFNPSKSSTYSTDRQTFSLQYGSGSLTGFFGYDTLKIQSIQVPDQEFGLSETEPGTSFLYAQFDGIMGLAYPDLSAGGATTAMQGLLQEDALTSPVFSFYLSNQQSSQDGGELVLGGVDSSLYTGQIYWAPVTQELYWQIGIEEFLIGDEASGWCSEGCQAIVDTGTSLLTVPQDYLSDLVQATGAEENEYGEFLVDCKDIQSLPTFTFIINGVEFPLPPSAYILEEDGFCMVGVEPTYVSSQNGQPLWILGDVFLRSYYSVFDLGNNRVGFATAA", "length": 357, "header": "tr|A0A4X1SIV5-1|A0A4X1SIV5_PIG Isoform 1 of Gastricsin OS=Sus scrofa OX=9823 GN=PGC PE=3 SV=1 CANONICAL=A0A4X1SIV5-1" }, "isoforms": [ { "isoform_ac": "A0A286ZP41-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5/entry#A0A286ZP41-1", "sequence": { "sequence": "MGMGIMKWMVVALVCLQLLEASVIKVPLKKLKSIRQAMKEKGLLEEFLKTHKYDPAQRYRFGDFSVALEPMAYLEAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCKSLACTTHARFNPSKSSTYSTDRQTFSLQYGSGSLTGFFGYDTLKIQSIQVPDQEFGLSETEPGTSFLYAQFDGIMGLAYPDLSAGGATTAMQGLLQEDALTSPVFSFYLSNQQSSQDGGELVLGGVDSSLYTGQIYWAPVTQELYWQIGIEEFLIGDEASGWCSEGCQAIVDTGTSLLTVPQDYLSDLVQATGAEENEYGEFLVDCKDIQSLPTFTFIINGVEFPLPPSAYILEEDGFCMVGVEPTYVSSQNGQPLWILGDVFLRSYYSVFDLGNNRVGFATAA", "length": 394, "header": "tr|A0A286ZP41-1|A0A4X1SIV5_PIG Computationally mapped isoform of Gastricsin OS=Sus scrofa OX=9823 GN=PGC PE=3 SV=1 CANONICAL=A0A4X1SIV5-1" }, "locus": { "chromosome": "7", "start_pos": 36932445, "end_pos": 36922418, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049978.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049978.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033353.1", "url": "https://www.ensembl.org/id/ENSSSCP00000033353.1" } ] } }, { "isoform_ac": "A0A4X1SIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5/entry#A0A4X1SIV5-1", "sequence": { "sequence": "MKEKGLLEEFLKTHKYDPAQRYRFGDFSVALEPMAYLEAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCKSLACTTHARFNPSKSSTYSTDRQTFSLQYGSGSLTGFFGYDTLKIQSIQVPDQEFGLSETEPGTSFLYAQFDGIMGLAYPDLSAGGATTAMQGLLQEDALTSPVFSFYLSNQQSSQDGGELVLGGVDSSLYTGQIYWAPVTQELYWQIGIEEFLIGDEASGWCSEGCQAIVDTGTSLLTVPQDYLSDLVQATGAEENEYGEFLVDCKDIQSLPTFTFIINGVEFPLPPSAYILEEDGFCMVGVEPTYVSSQNGQPLWILGDVFLRSYYSVFDLGNNRVGFATAA", "length": 357, "header": "tr|A0A4X1SIV5-1|A0A4X1SIV5_PIG Isoform 1 of Gastricsin OS=Sus scrofa OX=9823 GN=PGC PE=3 SV=1 CANONICAL=A0A4X1SIV5-1" }, "locus": { "chromosome": "7", "start_pos": 36930274, "end_pos": 36922418, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001807.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001807.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001761.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001761.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP41", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP41" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521201", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521201", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MWS3-1", "protein_name": "Gastricsin", "gene_name": "PGC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKWMVLALVCLQALEAAALVKIPLKKFKSIREIMKEKGLLEDFLRTYKHDPAQKYRFGDFIVATEPMDYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHTRFNHSLSSTYSTNEQTFSLQYGSGSLTGILGYDTLTVQGIKVPNQEFGLSKTEPGTNFLYAKFDGIMGMAYPSLSVDGATTVLQGMLQEGALTSPVFSFYLSSQQGSQDGGAVIFGGVDNCLYTGQIYWAPVTQELYWQIGFEEFLIGDQATGWCSTGCQAIVDTGTSLLTVPQQFLSALLQATGAQEDQYGQFPVDCNNIQNLPTLTFVINGVQFPLPPASYILNNDDSYCILGVEVTYVPSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFATAV", "length": 391 }, "evidence": [ { "id": "A0A4X1SIV5", "url": "https://omabrowser.org/oma/group/A0A4X1SIV5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3I107-1", "protein_name": "Gastricsin", "gene_name": "Pgc", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKWLVVALLCLPLLEAALVRVPLKKMKTIRQNMKEKGVLKDFLKTHKYDPAQKYRFGNFGDFSVLYEPIAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSIYCQSEACTTHPRYNPNKSSTYYTEGQTFSLQYGTGSLTGFFGYDTLTVQGIQVPNQEFGLSENEPGTNFVYADFDGIMGLAYPGLSAGGATTAMQGLLQEGALSQPLFGVYLGSQQGSNGGQIVFGGVDENLYTGEITWIPVTQELYWQITIDDFLIGDQVSGWCSQGCAGIVDTGTSLLTMPSQYLSDLLQTIGAQEGEYGEYFVSCDSVSSLPTFNFVLNGVEFPLSPSFYILQEDGVCMVGLESSPLTSESGQSMWILGDVFLRSYYAIFDMGNNRVGFATAV", "length": 391 }, "evidence": [ { "id": "A0A4X1SIV5", "url": "https://omabrowser.org/oma/group/A0A4X1SIV5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P04073-1", "protein_name": "Gastricsin", "gene_name": "Pgc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKWMVVALLCLPLLEASLLRVPLRKMKSIRETMKEQGVLKDFLKTHKYDPGQKYHFGNFGDYSVLYEPMAYMDASYFGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQSEACTTHARFNPSKSSTYYTEGQTFSLQYGTGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPGLSSGGATTALQGMLGEGALSQPLFGVYLGSQQGSNGGQIVFGGVDKNLYTGEITWVPVTQELYWQITIDDFLIGDQASGWCSSQGCQGIVDTGTSLLVMPAQYLSELLQTIGAQEGEYGEYFVSCDSVSSLPTLSFVLNGVQFPLSPSSYIIQEDNFCMVGLESISLTSESGQPLWILGDVFLRSYYAIFDMGNNKVGLATSV", "length": 392 }, "evidence": [ { "id": "A0A4X1SIV5", "url": "https://omabrowser.org/oma/group/A0A4X1SIV5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P20142-1", "protein_name": "Gastricsin", "gene_name": "PGC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKWMVVVLVCLQLLEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILSNNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFATAA", "length": 388 }, "evidence": [ { "id": "A0A4X1SIV5", "url": "https://omabrowser.org/oma/group/A0A4X1SIV5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7R7-1", "protein_name": "Gastricsin", "gene_name": "Pgc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKWMVVALLCLPLLEAALIRVPLKKMKSIRETMKEQGVLKDFLKNHKYDPGQKYHFGKFGDYSVLYEPMAYMDASYYGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQSEACTTHTRYNPSKSSTYYTQGQTFSLQYGTGSLTGFFGYDTLRVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPGLSSGGATTALQGMLGEGALSQPLFGVYLGSQQGSNGGQIVFGGVDENLYTGELTWIPVTQELYWQITIDDFLIGNQASGWCSSSGCQGIVDTGTSLLVMPAQYLNELLQTIGAQEGEYGQYFVSCDSVSSLPTLTFVLNGVQFPLSPSSYIIQEEGSCMVGLESLSLNAESGQPLWILGDVFLRSYYAVFDMGNNRVGLAPSV", "length": 392 }, "evidence": [ { "id": "A0A4X1SIV5", "url": "https://omabrowser.org/oma/group/A0A4X1SIV5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIV5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIV5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIV5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5" } ], "pmid": "" }, { "name": "digestion", "id": "GO:0007586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007586", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIV5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5" } ], "pmid": "" }, { "name": "positive regulation of antibacterial peptide production", "id": "GO:0002803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002803", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIV5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIV5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SIV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIV5" }, { "id": "PS51767", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51767" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase A1", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 354, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T0V4-1", "uniprot_ac": "A0A4X1T0V4", "uniprot_id": "A0A4X1T0V4_PIG", "mass": { "chemical_mass": 100041.0, "monoisotopic_mass": 100041.0 }, "refseq": { "ac": "XP_005656499", "name": "stonin-2 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656499" }, "gene_names": [ { "name": "STON2", "type": "recommended", "evidence": [ { "id": "A0A4X1T0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ] }, { "name": "STON2", "type": "synonym", "evidence": [ { "id": "XP_005656499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656499" } ] } ], "protein_names": [ { "name": "Stonin-2", "type": "recommended", "evidence": [ { "id": "A0A4X1T0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4/entry#names_and_taxonomy" } ] }, { "name": "stonin-2 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_005656499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656499" } ] } ], "function": [ { "annotation": "Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZR30", "url": "https://www.uniprot.org/uniprotkb/A0A286ZR30#function" }, { "database": "UniProtKB", "id": "PIRNR037099", "url": "https://www.uniprot.org/uniprotkb/PIRNR037099#function" }, { "database": "UniProtKB", "id": "A0A4X1SZL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZL5#function" }, { "database": "UniProtKB", "id": "ARBA00055858", "url": "https://www.uniprot.org/uniprotkb/ARBA00055858#function" }, { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "STON2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4", "locus": { "chromosome": "7", "start_pos": 104039493, "end_pos": 104189701, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002412", "url": "https://www.ensembl.org/id/ENSSSCG00000002412" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002412", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002412", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157426", "url": "https://www.ncbi.nlm.nih.gov/gene/100157426", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157426", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157426", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EWVSFND", "url": "https://omabrowser.org/oma/group/EWVSFND/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10529", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10529", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00928", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00928", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005656499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656499", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZR30", "url": "https://www.uniprot.org/uniprotkb/A0A286ZR30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZR30-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZR30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SZL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SZL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T0V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTLDHVIATHQSEWVSFSEEPLFPAPSEGSTEEHLPGPSSSSDQSESSSGENQVGDGGSQDLSHSEHDDSSEKTGLISEAASPPGSPEQPSPDLASAISSWVQFEDDTPWASTSPPHKEAGGTATSLTLPCWTCPSFDSLGRCPLPSENSWTTHSEDTSSPSFGPSYTDLQLVSAEEQMSGPASGADSTDNSSSLHEDEEVEMEAISWQASSPAMNGHPATPVTSARFPSWVTFDDNEVSCPLPPVTSPLKPKTPSIASVIPDVPYNSTGSFKKRERPKSTLMNFSKVQKLDISSLNHPPSVPEAPPWRATNPFLNETLQDIQPSPINPFRAFFEEQERRSQSNSVSGATGKSQRDSLIIIYQDAISFDDSSKTQSHSDAVEKLKRLQIEDPDHLGRVTLPDDDPIAWLELGDHPPGSVLSQPRDGWPMMLRIPEKKNIMSSRHWGPIYIKLTDSGYLQLYYEQGLEKPFREFKLEICHEISEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHMAEREQVIKLGTTNYDDFLSFIRAVQDHLMDLPVLSMDLSTVGLNYLEEEITVDVRDEFSGLVSKGDNQILQHCVLTRIHILSFLSGLAECRLGLNDVLVKGNEIVSRQDIMPTTTTKWIKLHECRFHGCVDEDVFNSSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTVASINGAEVEVQSWLRMSTGFSSNCDPLTQVPCENVMVRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSTSVSGSEPVMRVTLGTAKYEHAFNSIVWRITRLPDKNSASGHPHCFFCHLELGSDREVPSRFANYVNVEFSMPTTSASKAAVRSISVEDKTDVRKWVNYSAHYSYKVEIEQKKSLKPDFEGDEVENPKECGVQ", "length": 898, "header": "tr|A0A4X1T0V4-1|A0A4X1T0V4_PIG Isoform 1 of Stonin-2 OS=Sus scrofa OX=9823 GN=STON2 PE=3 SV=1 CANONICAL=A0A4X1T0V4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZR30-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4/entry#A0A286ZR30-1", "sequence": { "sequence": "MTTLDHVIATHQSEWVSFSEEPLFPAPSEGSTEEHLPGPSSSSDQSESSSGENQVGDGGSQDLSHSEHDDSSEKTGLISEAASPPGSPEQPSPDLASAISSWVQFEDDTPWASTSPPHKEAGGTATSLTLPCWTCPSFDSLGRCPLPSENSWTTHSEDTSSPSFGPSYTDLQLVSAEEQMSGPASGADSTDERTKWQTGRQTAVSPVQACTEHTSTCTHGLDPSPPSAHPRRNQSPSKGLEGASAPSDNSSSLHEDEEVEMEAISWQASSPAMNGHPATPVTSARFPSWVTFDDNEVSCPLPPVTSPLKPKTPSIASVIPDVPYNSTGSFKKRERPKSTLMNFSKVQKLDISSLNHPPSVPEAPPWRATNPFLNETLQDIQPSPINPFRAFFEEQERRSQSNSVSGATGKSQRDSLIIIYQDAISFDDSSKTQSHSDAVEKLKRLQIEDPDHLGRVTLPDDDPIAWLELGDHPPGSVLSQPRDGWPMMLRIPEKKNIMSSRHWGPIYIKLTDSGYLQLYYEQGLEKPFREFKLEICHEISEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHMAEREQVIKLGTTNYDDFLSFIRAVQDHLMDLPVLSMDLSTVGLNYLEEEITVDVRDEFSGLVSKGDNQILQHCVLTRIHILSFLSGLAECRLGLNDVLVKGNEIVSRQDIMPTTTTKWIKLHECRFHGCVDEDVFNSSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTVASINGAEVEVQSWLRMSTGFSSNCDPLTQVPCENVMVRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSTSVSGSEPVMRVTLGTAKYEHAFNSIVWRITRLPDKNSGRQSRLFCENCHRVAKELGSKFHILFPYQVLAFVK", "length": 895, "header": "tr|A0A286ZR30-1|A0A4X1T0V4_PIG Computationally mapped isoform of Stonin-2 OS=Sus scrofa OX=9823 GN=STON2 PE=3 SV=2 CANONICAL=A0A4X1T0V4-1" }, "locus": { "chromosome": "7", "start_pos": 104157350, "end_pos": 104047788, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039865.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039865.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033925.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033925.2" } ] } }, { "isoform_ac": "A0A4X1SZL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4/entry#A0A4X1SZL5-1", "sequence": { "sequence": "MTTLDHVIATHQSEWVSFSEEPLFPAPSEGSTEEHLPGPSSSSDQSESSSGENQVGDGGSQDLSHSEHDDSSEKTGLISEAASPPGSPEQPSPDLASAISSWVQFEDDTPWASTSPPHKEAGGTDNSSSLHEDEEVEMEAISWQASSPAMNGHPATPVTSARFPSWVTFDDNEVSCPLPPVTSPLKPKTPSIASVIPDVPYNSTGSFKKRERPKSTLMNFSKVQKLDISSLNHPPSVPEAPPWRATNPFLNETLQDIQPSPINPFRAFFEEQERRSQSNSVSGATGKSQRDSLIIIYQDAISFDDSSKTQSHSDAVEKLKRLQIEDPDHLGRVTLPDDDPIAWLELGDHPPGSVLSQPRDGWPMMLRIPEKKNIMSSRHWGPIYIKLTDSGYLQLYYEQGLEKPFREFKLEICHEISEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHMAEREQVIKLGTTNYDDFLSFIRAVQDHLMDLPVLSMDLSTVGLNYLEEEITVDVRDEFSGLVSKGDNQILQHCVLTRIHILSFLSGLAECRLGLNDVLVKGNEIVSRQDIMPTTTTKWIKLHECRFHGCVDEDVFNSSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTVASINGAEVEVQSWLRMSTGFSSNCDPLTQVPCENVMVRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSTSVSGSEPVMRVTLGTAKYEHAFNSIVWRITRLPDKNSASGHPHCFFCHLELGSDREVPSRFANYVNVEFSMPTTSASKAAVRSISVEDKTDVRKWVNYSAHYSYKVEIEQKKSLKPDFEGDEVENPKECGVQ", "length": 832, "header": "tr|A0A4X1SZL5-1|A0A4X1SZL5_PIG Computationally mapped isoform of Stonin-2 OS=Sus scrofa OX=9823 GN=STON2 PE=3 SV=1 CANONICAL=A0A4X1T0V4-1" }, "locus": { "chromosome": "7", "start_pos": 104157350, "end_pos": 104039958, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002681.4", "url": "https://www.ensembl.org/id/ENSSSCT00000002681.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002614.4", "url": "https://www.ensembl.org/id/ENSSSCP00000002614.4" } ] } }, { "isoform_ac": "A0A4X1T0V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4/entry#A0A4X1T0V4-1", "sequence": { "sequence": "MTTLDHVIATHQSEWVSFSEEPLFPAPSEGSTEEHLPGPSSSSDQSESSSGENQVGDGGSQDLSHSEHDDSSEKTGLISEAASPPGSPEQPSPDLASAISSWVQFEDDTPWASTSPPHKEAGGTATSLTLPCWTCPSFDSLGRCPLPSENSWTTHSEDTSSPSFGPSYTDLQLVSAEEQMSGPASGADSTDNSSSLHEDEEVEMEAISWQASSPAMNGHPATPVTSARFPSWVTFDDNEVSCPLPPVTSPLKPKTPSIASVIPDVPYNSTGSFKKRERPKSTLMNFSKVQKLDISSLNHPPSVPEAPPWRATNPFLNETLQDIQPSPINPFRAFFEEQERRSQSNSVSGATGKSQRDSLIIIYQDAISFDDSSKTQSHSDAVEKLKRLQIEDPDHLGRVTLPDDDPIAWLELGDHPPGSVLSQPRDGWPMMLRIPEKKNIMSSRHWGPIYIKLTDSGYLQLYYEQGLEKPFREFKLEICHEISEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHMAEREQVIKLGTTNYDDFLSFIRAVQDHLMDLPVLSMDLSTVGLNYLEEEITVDVRDEFSGLVSKGDNQILQHCVLTRIHILSFLSGLAECRLGLNDVLVKGNEIVSRQDIMPTTTTKWIKLHECRFHGCVDEDVFNSSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTVASINGAEVEVQSWLRMSTGFSSNCDPLTQVPCENVMVRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSTSVSGSEPVMRVTLGTAKYEHAFNSIVWRITRLPDKNSASGHPHCFFCHLELGSDREVPSRFANYVNVEFSMPTTSASKAAVRSISVEDKTDVRKWVNYSAHYSYKVEIEQKKSLKPDFEGDEVENPKECGVQ", "length": 898, "header": "tr|A0A4X1T0V4-1|A0A4X1T0V4_PIG Isoform 1 of Stonin-2 OS=Sus scrofa OX=9823 GN=STON2 PE=3 SV=1 CANONICAL=A0A4X1T0V4-1" }, "locus": { "chromosome": "7", "start_pos": 104157350, "end_pos": 104039958, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086410.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086410.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074486.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074486.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZR30", "url": "https://www.uniprot.org/uniprotkb/A0A286ZR30" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157426", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157426", "resource": "KEGG Pathway" }, { "id": "R-SSC-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-SSC-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M4Q2-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTTLDHVIATHQSEWVSFNEEPLFPVPSEGGPKEHLPGASSSSDQSESSSGEHHALDGGSQDLSHSEHDDSSEKLGLISEAASPPGSPEQRPPELVSAISSWVQFEDDAPWASSSPPPKEAGGTATSLAMPCWTCPSFDSLGRCPLPSESSWTTHSEDTSSPSFGPSYTDLQLVSAGEQSGLASGADSTDNSSSLQEDEEVEMEAISWQAGSPAMNGHPTTPVTSARFPSWVTFDDNEVSGPLSPITSPLKPETLPLASVTPDGPYNLTGSFKKRERPKSSLMNFSKVQKLDVSSVSHPPAVPEAPPWRATNPFLNETLQDVQPSPINPFRAFFEEQERRAQSSSVSSTLGKSQRDSLIVVYRDAISFDDSSRNQSRSDAVEKLKRLQIEDSDHLGGVTLPDDDPAAWAELDAHPAGSEQSPPRDGWPMMLRIPEKKNIMSSRHWGPIYVKLTDGGYLQLYYEQGLERPFREFKLEMYHEISEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHLAEREQVIKLGTTNYEDFLSFIRAVQDRLMELPVLSTELSTVGLNYLEEEMTVDVQDEFSGLVSKGDNQILQHRVLTRIHVLSFLSGLAECRLGLNDVLVKGNEVVSRQDIVPTTTTKWIRLHECRFHGCVDEDVFRGSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTAASIHGAEVEVQSWLRMSAGFSSNWDPLTQVPCENVMVRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSASISGSEPVMRVTLGTAKYEHAFNAIVWRINRLPDKNSASGHPHCFFCHLELGSDREVPSRFANHVNVEFSMPTTSASKAAVRSISVEDKTDVRKWVNYSAHYSYKVEIEQKKSLKLDLEGDDMENPKECGVQ", "length": 897 }, "evidence": [ { "id": "A0A4X1T0V4", "url": "https://omabrowser.org/oma/group/A0A4X1T0V4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2QMI2-1", "protein_name": "Stonin-2", "gene_name": "Ston2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTTLDHVIATHQSEWVSFSEEPLFPAPSEGVTEEHFPGSSSSSDPSESSSGENPAVDGGCQDLSHSEQDDSSEKMGLISEATTPPGSPMQATPDLASAISNWVQFEDDTPWSNTSPPHKETALTLTMPCWTCPSFDSLRRCPLTSESSWTTHSEDTSSPSVAPSYTDLQLINTEEQASGRASRTDSTTDNSSSLQEDEEVEMEAISWRAGSPAMNGHPTVPPVTTARFPSWVTFDDSEVSCPLPPPVTSPMKPSTPPVATAIPDVPYNSTGSFKRDRPKSTLMNFSKVQKLDISPLNRPPSVIEAPPWRATNPFLNETLQDVQPSPINPFSAFFEEQERRSQNSSVSSTTGKSQRDSLIVIYQDAISFEDSGKSQPQPDAAIEKLKQLQIDDPDRVGSTSLPDDDPIAWVELDAHSPASALSQPRDGWPMMLRIPEKKNIMSSRHWGPIYIKLTDSGYLQLYYEQGLEKPFREFKLEICHEVSEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHTAEREQVIKLGTTNYDDFLSFIHAVQDCLMDLPVLSMDLSTVGLNYLEEEITVDVRDEFSGTVSKGDNRILQHCVLTRIHILSFLSGLAECRLGLNDILIKGNEIVSRQDIMPTTTTKWVKLHECRFHGCVDEDVFNSSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTAASINGAEVEVQSWLRMSPGFSSNRDPLTQVPCENVMVRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSAGISGSEPVMRVTLGTAKYEHAFNAIVWRINRLPDKNSASGHPHCFFCHLELGSDREVPSRFANYVNVEFSMPTTSASKAAVRSISVEDKPGVRKWVNYSAHYSYKVEIEQKKSLKPDFEGEELDNPKECGVQ", "length": 898 }, "evidence": [ { "id": "A0A4X1T0V4", "url": "https://omabrowser.org/oma/group/A0A4X1T0V4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4AB66-1", "protein_name": "Stonin-2", "gene_name": "Ston2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTLDHVIATHQSEWVSFSEEPLFPTPLEGGTEEHFPGLSSSSDRSESSSGENHAVDEGSQDLSHSEQDDSSEKMGLISEAASPPGSPVQPTPDLASAISNWVQFEDDTPWSNTSAPHKETALTLTVPCWTCPSLDSLRRCPLASESSWTTHSEDTSSPSVAPSYTDLQLINAEEQASGRASGTDSTDNSSSLQEDEEVEMETISWWAGSPAMNGHPAVPQVTTARFPSWVTFEDNEVGCPSPTVPSPKKPNAPSAATAGPDVPFNSTGSFKRDRPKSTLMNLSKVQKLDISSLNRPPSVTEAPPWRATNPFLNESLQDIQPSPINPFSAFFEEQERRSQNSSISGTSGKSQRDSLIVIYQDAISFDDSGKSQSHPDAIEKLKQLQIDDPDPVGNAALPDDDPTASVEPDAPSPTSALSQPRDGWPMMLRIPEKKNIMSSRHWGPIYIKLTDSGYLQLYYEQGLEKPFREFKLEICHEVSEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHAAEREQVIKLGTTNYDDFLSFIHAVQDRLMDLPVQSMDLSTVGLNYLEEEITVDIRDEFSGTVSKGDNQILQHHVLTRIHILSFLSGLAECRLGLNDILIKGNEIVSRQDIMPTTTTKWIKLHECRFHGCVDEDVFNSSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTAASINGAEVEVQSWLRMSPGFSSNRDPLTQVPCENVMVRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSAGASGSEPVMRVTLGTAKYEHAFNSIVWRINRLPDKNSASGHPHCFFCHLELGSDREVPSRFANHVNVEFSMPTTSASKAAVRSISVEDKPDVRKWVNYSAHYSYKVEIEQKKSLKPDFEGEDLENPKECGVQ", "length": 895 }, "evidence": [ { "id": "A0A4X1T0V4", "url": "https://omabrowser.org/oma/group/A0A4X1T0V4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BZ60-1", "protein_name": "Stonin-2", "gene_name": "Ston2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTLDHVIATHQSEWVSFSEEPLFPTPLEGGTEEHFPGLSSSSERSESSSGENHVVDEGSQDLSHSEQDDSSEKMGLISEAASPPGSPVQPTPDLASAISNWVQFEDDTPWSSTSPPHKETALTLTMPCWTCPSFDSLRRCPLTSESSWTTHSEDTSSPSVAPSYTDLQLINTEEQASGRASGTDSTDNSSSLQEDEEVEMEAISWWAGSPAMNGHPAAPPVTTARFPSWVTFEDNEVGCPSPPVPSPKKPNTPSAATAAPDVPFNSTGSFKRDRPKSTLMNLPKVQKLDISSLNRPPSVIEAPPWRATNPFLNETLQDVQPSPINPFSAFFEEQERRSQNSSVSSTTGKSQRDSLIVVYQDAISFDDSGKSQPHPDAIEKLKQLQIDDPDPVGNTALPDDDPTASVELDAPSPASALSQPRDGWPMMLRIPEKKNIMSSRHWGPIYIKLTASGYLQLYYEQGLEKPFREFKLEICHEVSEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHAAEREQVIKLGTTNYDDFRSFIHAVQDRLMDLPVLSMDLSTVGLNYLEEEITVDVRDEFSGTVGKGDNQILQHHVLTRIHILSFLSGLAECRLGLNDILIKGNEIVSRQDIMPTTTTKWIKLHECRFHGCVDEDVFNSSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTAASINGAEVEVQSWLRMSPGFSSNRDPLTQVPCENVMVRYPVPSEWVKNFRRDSVLGEKSLKAKVNRGASFGSAGASGSEPVMRVTLGTAKYEHAFNSIVWRINRLPDKNSASGHPHCFFCHLELGSDREVPSRFANYVNVEFSMPTTSASKAAVRSVSVEDKPDVRKWVNYSAHYSYKVEIEQKKSLKPDFEGEDLENPKECGVQ", "length": 895 }, "evidence": [ { "id": "A0A4X1T0V4", "url": "https://omabrowser.org/oma/group/A0A4X1T0V4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTLDHVIATHQSEWVSFNEEPPFPAHSQGGTEEHLPGLSSSPDQSESSSGENHVVDGGSQDHSHSEQDDSSEKMGLISEAASPPGSPEQPPPDLASAISNWVQFEDDTPWASTSPPHQETAETALPLTMPCWTCPSFDSLGRCPLTSESSWTTHSEDTSSPSFGCSYTDLQLINAEEQTSGQASGADSTDNSSSLQEDEEVEMEAISWQASSPAMNGHPAPPVTSARFPSWVTFDDNEVSCPLPPVTSPLKPNTPPSASVIPDVPYNSMGSFKKRDRPKSTLMNFSKVQKLDISSLNRTPSVTEASPWRATNPFLNETLQDVQPSPINPFSAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQIDDPDHFGSATLPDDDPVAWIELDAHPPGSARSQPRDGWPMMLRIPEKKNIMSSRHWGPIFVKLTDTGYLQLYYEQGLEKPFREFKLEICHEISEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHTAEREQVIKLGTTNYDDFLSFIHAVQDRLMDLPVLSMDLSTVGLNYLEEEITVDVRDEFSGIVSKGDNQILQHHVLTRIHILSFLSGLAECRLGLNDILVKGNEIVLRQDIMPTTTTKWIKLHECRFHGCVDEDVFHNSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTATSVNGAEVEVQSWLRMSTGFSANRDPLTQVPCENVMIRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSTSVSGSEPVMRVTLGTAKYEHAFNSIVWRINRLPDKNSASGHPHCFFCHLELGSDREVPSRFANHVNVEFSMPTTSASKASVRSISVEDKTDVRKWVNYSAHYSYQVALGSIWLMLPTPFVHPTTLPLLFLLAMLTMFAW", "length": 905 }, "evidence": [ { "id": "A0A4X1T0V4", "url": "https://omabrowser.org/oma/group/A0A4X1T0V4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" }, { "name": "AP-2 adaptor complex", "id": "GO:0030122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030122", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" }, { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0V4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 657, "end_pos": 659, "annotation": "n_glycosylation_sequon" }, { "start_pos": 863, "end_pos": 865, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" }, { "id": "PS51072", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51072" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MHD", "eco_id": "ECO_0000259", "start_pos": 568, "end_pos": 875, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0V4" }, { "id": "PS51070", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51070" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SHD", "eco_id": "ECO_0000259", "start_pos": 427, "end_pos": 560, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 657, "end_pos": 659 }, { "start_pos": 863, "end_pos": 865 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TNJ8-1", "uniprot_ac": "A0A4X1TNJ8", "uniprot_id": "A0A4X1TNJ8_PIG", "mass": { "chemical_mass": 53519.0, "monoisotopic_mass": 53519.0 }, "refseq": { "ac": "XP_003128538", "name": "serine/threonine-protein kinase ULK3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128538" }, "gene_names": [ { "name": "ULK3", "type": "recommended", "evidence": [ { "id": "A0A4X1TNJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ] }, { "name": "ULK3", "type": "synonym", "evidence": [ { "id": "XP_003128538", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128538" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase ULK3", "type": "recommended", "evidence": [ { "id": "A0A4X1TNJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A4X1TNJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8/entry#names_and_taxonomy" } ] }, { "name": "Unc-51-like kinase 3", "type": "synonym", "evidence": [ { "id": "A0A4X1TNJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase ULK3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_003128538", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128538" } ] } ], "function": [ { "annotation": "Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8#function" }, { "database": "UniProtKB", "id": "ARBA00055316", "url": "https://www.uniprot.org/uniprotkb/ARBA00055316#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ULK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8", "locus": { "chromosome": "7", "start_pos": 58707187, "end_pos": 58699984, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001898", "url": "https://www.ensembl.org/id/ENSSSCG00000001898" } ] } } ], "crossref": [ { "id": "A0A4X1TNJ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TNJ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001898", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001898", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02684", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02684", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14121", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14121", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100520750", "url": "https://www.ncbi.nlm.nih.gov/gene/100520750", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520750", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520750", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TQAVEHD", "url": "https://omabrowser.org/oma/group/TQAVEHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TNJ8", "url": "https://www.orthodb.org/?gene=A0A4X1TNJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24348:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24348:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5632684", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5632684", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003128538", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128538", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZSX7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZSX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLH8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TNJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPGWGPPRLEGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSVGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLSQDCRDLLQRLLERDPNRRISFQDFFAHPWVDLEHMPSGESLARATALVVQAVQKDQQGDAAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSSSNRALLRQETSARDLLKEMARDKPRLLAALEVASAAMAKAEEAGGEQDALVLYQHSLGELLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKMRESRWEAETLDKEGLLESVRSSCTLQ", "length": 472, "header": "tr|A0A4X1TNJ8-1|A0A4X1TNJ8_PIG Isoform 1 of Serine/threonine-protein kinase ULK3 OS=Sus scrofa OX=9823 GN=ULK3 PE=3 SV=1 CANONICAL=A0A4X1TNJ8-1" }, "isoforms": [ { "isoform_ac": "A0A286ZSX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8/entry#A0A286ZSX7-1", "sequence": { "sequence": "MAGPGWGPPRLEGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSLPLRPLLSQDCRDLLQRLLERDPNRRISFQDFFAHPWVDLEHMPSGESLARATALVVQAVQKDQQGDAAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSSSNRALLRQETSARDLLKEMARDKPRLLAALEVASAAMAKAEEAGGEQDALVLYQHSLGELLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKMRESRWEAETLDKEGLLESVRSSCTLQ", "length": 438, "header": "tr|A0A286ZSX7-1|A0A4X1TNJ8_PIG Computationally mapped isoform of Serine/threonine-protein kinase ULK3 OS=Sus scrofa OX=9823 GN=ULK3 PE=3 SV=2 CANONICAL=A0A4X1TNJ8-1" }, "locus": { "chromosome": "7", "start_pos": 58706091, "end_pos": 58700116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064590.2", "url": "https://www.ensembl.org/id/ENSSSCT00000064590.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034567.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034567.2" } ] } }, { "isoform_ac": "A0A4X1TLH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8/entry#A0A4X1TLH8-1", "sequence": { "sequence": "MAGPGWGPPRLEGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLDFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSVGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLSQDCRDLLQRLLERDPNRRISFQDFFAHPWVDLEHMPSGESLARATALVVQAVQKDQQGDAAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSSSNRALLRQETSARDLLKEMARDKPRLLAALEVASAAMAKAEEAGGEQDALVLYQHSLGELLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKMRESRWEAETLDKEGLLESVRSSCTLQ", "length": 437, "header": "tr|A0A4X1TLH8-1|A0A4X1TLH8_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=ULK3 PE=4 SV=1 CANONICAL=A0A4X1TNJ8-1" }, "locus": { "chromosome": "7", "start_pos": 58706091, "end_pos": 58700116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002126.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002126.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002076.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002076.3" } ] } }, { "isoform_ac": "A0A4X1TNJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8/entry#A0A4X1TNJ8-1", "sequence": { "sequence": "MAGPGWGPPRLEGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSVGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLSQDCRDLLQRLLERDPNRRISFQDFFAHPWVDLEHMPSGESLARATALVVQAVQKDQQGDAAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSSSNRALLRQETSARDLLKEMARDKPRLLAALEVASAAMAKAEEAGGEQDALVLYQHSLGELLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKMRESRWEAETLDKEGLLESVRSSCTLQ", "length": 472, "header": "tr|A0A4X1TNJ8-1|A0A4X1TNJ8_PIG Isoform 1 of Serine/threonine-protein kinase ULK3 OS=Sus scrofa OX=9823 GN=ULK3 PE=3 SV=1 CANONICAL=A0A4X1TNJ8-1" }, "locus": { "chromosome": "7", "start_pos": 58706091, "end_pos": 58700116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057758.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057758.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038205.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038205.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZSX7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSX7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520750", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520750", "resource": "KEGG Pathway" }, { "id": "R-SSC-5632684", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5632684", "resource": "Reactome", "description": "Hedgehog 'on' state" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A0W4-1", "protein_name": "Serine/threonine-protein kinase ULK3", "gene_name": "ULK3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGGGCAPPRLDGFVLTERLGTGTYATVYKAYGKRDTREVVAVKCVSKRSLNRASVENLLTEIEILKTIRHPHIVELKDFQWDSDHIYLIMEFCAGGDLSRFIRMRRILPEKVARIFLQQLACALKFLHDHNISHLDLKPQNILLSTPENPQLKLADFGFAQYMSPWDEKHVLRGSPLYMAPEMVCRQQYDARVDLWSVGVILYEALFGRPPFASRSFAELEEKIRSDRAIELPSRPPLSPECRDLLQRLLERDPLKRISFEEFFAHPFVDMEHMPGPESFCKATNLVVEAVKKDQEGDASAALSLYCKALEYFVPALHYESDARRKEAIRTKVGQYISRAEELKALVASKSKNLLQQGNPAREILKEMAKDKPRLCAALEMASVAVAREEEGKDDGDTLELYQQSLGELLLLLAEPAGRRRELLHAEIQTLMARAEYLKDQIKMREAQSMGKEALADSVRSSCTLQ", "length": 467 }, "evidence": [ { "id": "A0A4X1TNJ8", "url": "https://omabrowser.org/oma/group/A0A4X1TNJ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7JQD1-1", "protein_name": "Serine/threonine-protein kinase ULK3", "gene_name": "Ulk3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGPGWGLPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDNDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALKFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSTGVILYASPLPSSTEALFGKPPFASRSFSELEEKIRSNRVIELPLRPQLSLDCRDLLQRLLERDPSRRISFQDFFAHPWVDLEHMPSGESLARATALVVEAVKKDQEGDTAAALSLYCKALDFFVPALHYEVDTQRKEAIKAKVAQYVSRAEELKAIVSSSNQALLRQGTSVQGLLREMARDKPRLLAALEVASAAMAKEEEAGKEQDALDLYQHSLGELLLLLAAEAPGRRRELLHTEVQNLMARAEYLKEQIKIRESHWEAETLDKEGLSESVRSSCTLQ", "length": 480 }, "evidence": [ { "id": "A0A4X1TNJ8", "url": "https://omabrowser.org/oma/group/A0A4X1TNJ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZHP7-1", "protein_name": "Serine/threonine-protein kinase ULK3", "gene_name": "Ulk3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGSGWGLPRLDGFILTERLGSGTYATVYKAYAKKATREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDNDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCRRQYDARVDLWSVGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPQLSLDCRDLLQRLLERDPSHRISFQDFFAHPWVDLEHMPSGESLAQATALVVEAVKKDQEGDAAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSSSNQALLRQGTTGQELLREMARDKPRLLAALEVASAAMAKEEEAGKEQDALDLYQHSLGELLLLLAAEAPGRRRELLHTEVQNLMARAEYLKEQIKIRESHWEAESLDKEGLSESVRSSCTLQ", "length": 472 }, "evidence": [ { "id": "A0A4X1TNJ8", "url": "https://omabrowser.org/oma/group/A0A4X1TNJ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3U3Q1-1", "protein_name": "Serine/threonine-protein kinase ULK3", "gene_name": "Ulk3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGPSWGLPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDNDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCRRQYDARVDLWSVGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPQLSLDCRDLLQRLLERDPARRISFKDFFAHPWVDLEHMPSGESLAQARALVVEAVKKDQEGDAAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSSSNQALLRQGTTVQELLREMARDKPRLLAALEVASAALAKEEEAGKEQDALDLYQHSLGELLVLLAAEAPGRRRELLHTEVQNLMARAEYLKEQIKIRESHWEAESLDKEGLSESVRSSCTLQ", "length": 472 }, "evidence": [ { "id": "A0A4X1TNJ8", "url": "https://omabrowser.org/oma/group/A0A4X1TNJ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6PHR2-1", "protein_name": "Serine/threonine-protein kinase ULK3", "gene_name": "ULK3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLSRDCRDLLQRLLERDPSRRISFQDFFAHPWVDLEHMPSGESLGRATALVVQAVKKDQEGDSAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSSSNQALLRQGTSARDLLREMARDKPRLLAALEVASAAMAKEEAAGGEQDALDLYQHSLGELLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKMRESRWEADTLDKEGLSESVRSSCTLQ", "length": 472 }, "evidence": [ { "id": "A0A4X1TNJ8", "url": "https://omabrowser.org/oma/group/A0A4X1TNJ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VHF6-1", "protein_name": "Serine/threonine-protein kinase ULK3", "gene_name": "Aduk", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLPRITDFEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSRENLITEIRLLRELKHKYIVTLQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKALPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLTRGANNVSLKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYDAKADLWSIGVILYECLFGKAPYSSRTIEELLLRIRKAEAITLPPNARISNECHDLLRRLLAHEPTARISFADFFAHPFLDLKTFPTEHTLQKAIDLVTQACAYDEKHNYKEAYYLYCSALQYFVPLITEETDATKRLALRNRALSYTKRAEEIKNCIIEDEYRMLAERQRQAATAATANQEPSSATQVPAAQPSSSRVAEMLEPDSRYKQLYALSNSSPSMKTGLEIGRKGELYLYERKLDAALESYTSALGILVPFVNNEPKGERRNLLLQQLEFWMKEAESIKSILSAKHLDDEEQKLSTRTSLRTITFQGWSKPPLIFFILFIVLNLIKIV", "length": 520 }, "evidence": [ { "id": "A0A4X1TNJ8", "url": "https://omabrowser.org/oma/group/A0A4X1TNJ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "fibroblast activation", "id": "GO:0072537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072537", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-SSC-5635839", "name": "ULK3:SUFU dissociates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cilium", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5635839", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5635839" } ] }, { "id": "R-SSC-5635842", "name": "ULK3 phosphorylates GLI", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "ciliary tip", "input_participant_list": [ "R-ALL-5632460" ], "output_participant_list": [ "R-ALL-5632457" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5635842", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5635842" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5632457", "participant_name": "ADP [cilium]", "crossref": [ { "id": "ZINC000012360703", "database": "ZINC", "url": "" }, { "id": "456216", "database": "ChEBI", "url": "" }, { "id": "C00008", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-5632460", "participant_name": "ATP [cilium]", "crossref": [ { "id": "30616", "database": "ChEBI", "url": "" }, { "id": "ZINC000004261765", "database": "ZINC", "url": "" }, { "id": "C00002", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TNJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNJ8" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 270, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T887-1", "uniprot_ac": "A0A4X1T887", "uniprot_id": "A0A4X1T887_PIG", "mass": { "chemical_mass": 54142.0, "monoisotopic_mass": 54142.0 }, "refseq": { "ac": "XP_005652939", "name": "nuclear factor 1 X-type isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652939" }, "gene_names": [ { "name": "NFIX", "type": "recommended", "evidence": [ { "id": "A0A4X1T887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ] }, { "name": "NFIX", "type": "synonym", "evidence": [ { "id": "XP_005652939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652939" } ] } ], "protein_names": [ { "name": "Nuclear factor 1", "type": "recommended", "evidence": [ { "id": "A0A4X1T887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887/entry#names_and_taxonomy" } ] }, { "name": "nuclear factor 1 X-type isoform X4", "type": "synonym", "evidence": [ { "id": "XP_005652939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652939" } ] } ], "function": [ { "annotation": "Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT86", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT86#function" }, { "database": "UniProtKB", "id": "RU000690", "url": "https://www.uniprot.org/uniprotkb/RU000690#function" }, { "database": "UniProtKB", "id": "A0A287A966", "url": "https://www.uniprot.org/uniprotkb/A0A287A966#function" }, { "database": "UniProtKB", "id": "A0A287B4C0", "url": "https://www.uniprot.org/uniprotkb/A0A287B4C0#function" }, { "database": "UniProtKB", "id": "A0A287B6I5", "url": "https://www.uniprot.org/uniprotkb/A0A287B6I5#function" }, { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887#function" }, { "database": "UniProtKB", "id": "F1SDA0", "url": "https://www.uniprot.org/uniprotkb/F1SDA0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NFIX", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887", "locus": { "chromosome": "2", "start_pos": 65954811, "end_pos": 66056567, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013742", "url": "https://www.ensembl.org/id/ENSSSCG00000013742" } ] } } ], "crossref": [ { "id": "A0A4X1T887", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T887", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013742", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013742", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100523536", "url": "https://www.ncbi.nlm.nih.gov/gene/100523536", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523536", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523536", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAHAAYE", "url": "https://omabrowser.org/oma/group/CAHAAYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287A966", "url": "https://www.orthodb.org/?gene=A0A287A966", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T887", "url": "https://www.orthodb.org/?gene=A0A4X1T887", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11492", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11492", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11492:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11492:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00859", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00859", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03165", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03165", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10524", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10524", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005652939", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652939", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZT86", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZT86-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A966", "url": "https://www.uniprot.org/uniprotkb/A0A287A966", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A966-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A966-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B4C0", "url": "https://www.uniprot.org/uniprotkb/A0A287B4C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B4C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B4C0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B6I5", "url": "https://www.uniprot.org/uniprotkb/A0A287B6I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B6I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B6I5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T887-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SDA0", "url": "https://www.uniprot.org/uniprotkb/F1SDA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SDA0-1", "url": "https://www.uniprot.org/uniprotkb/F1SDA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPDGAALTPPSPSFATTGASSANRFVSIGPRDGNFLNIPQQSQSWFL", "length": 494, "header": "tr|A0A4X1T887-1|A0A4X1T887_PIG Isoform 1 of Nuclear factor 1 OS=Sus scrofa OX=9823 GN=NFIX PE=1 SV=1 CANONICAL=A0A4X1T887-1" }, "isoforms": [ { "isoform_ac": "A0A286ZT86-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887/entry#A0A286ZT86-1", "sequence": { "sequence": "MPRVAFNPNVAGITTLLELTRSVLFRITVINISIGVYNKAEITYLGFRSDFKNAGVDVPIGAGEKRMKTAWGGEAKSVSSLAPGCHVLSSWGWPKPYQCRGVRRPPHVLRVHLQAFVQTGHRAGARRHEFEAAIEHGDVMGATEPGGDTSSDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQHSQRQAPPLPTGLSASDPGTATF", "length": 542, "header": "tr|A0A286ZT86-1|A0A4X1T887_PIG Computationally mapped isoform of Nuclear factor 1 OS=Sus scrofa OX=9823 GN=NFIX PE=1 SV=2 CANONICAL=A0A4X1T887-1" }, "locus": { "chromosome": "2", "start_pos": 66029515, "end_pos": 65963752, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064426.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064426.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034781.3", "url": "https://www.ensembl.org/id/ENSSSCP00000034781.3" } ] } }, { "isoform_ac": "A0A287A966-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887/entry#A0A287A966-1", "sequence": { "sequence": "MEMSWARQSLAGIPAACDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPDGAALTPPSPSFATTGASSANRFVSIGPRDGNFLNIPQQSQSWFL", "length": 510, "header": "tr|A0A287A966-1|A0A4X1T887_PIG Computationally mapped isoform of Nuclear factor 1 OS=Sus scrofa OX=9823 GN=NFIX PE=1 SV=2 CANONICAL=A0A4X1T887-1" }, "locus": { "chromosome": "2", "start_pos": 66029109, "end_pos": 65959044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054859.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054859.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040483.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040483.2" } ] } }, { "isoform_ac": "A0A287B4C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887/entry#A0A287B4C0-1", "sequence": { "sequence": "MGDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQHSQRQAPPLPTGLSASDPGTATF", "length": 434, "header": "tr|A0A287B4C0-1|A0A4X1T887_PIG Computationally mapped isoform of Nuclear factor 1 OS=Sus scrofa OX=9823 GN=NFIX PE=1 SV=3 CANONICAL=A0A4X1T887-1" }, "locus": { "chromosome": "2", "start_pos": 66028928, "end_pos": 65963752, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046203.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046203.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051129.3", "url": "https://www.ensembl.org/id/ENSSSCP00000051129.3" } ] } }, { "isoform_ac": "A0A287B6I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887/entry#A0A287B6I5-1", "sequence": { "sequence": "EYCLYEDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPDGAALTPPSPSFATTGASSANRFVSIGPRDGNFLNIPQQSQ", "length": 495, "header": "tr|A0A287B6I5-1|A0A4X1T887_PIG Computationally mapped isoform of Nuclear factor 1 OS=Sus scrofa OX=9823 GN=NFIX PE=1 SV=3 CANONICAL=A0A4X1T887-1" }, "locus": { "chromosome": "2", "start_pos": 66034449, "end_pos": 65963729, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060421.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060421.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051684.3", "url": "https://www.ensembl.org/id/ENSSSCP00000051684.3" } ] } }, { "isoform_ac": "A0A4X1T887-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887/entry#A0A4X1T887-1", "sequence": { "sequence": "MDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPDGAALTPPSPSFATTGASSANRFVSIGPRDGNFLNIPQQSQSWFL", "length": 494, "header": "tr|A0A4X1T887-1|A0A4X1T887_PIG Isoform 1 of Nuclear factor 1 OS=Sus scrofa OX=9823 GN=NFIX PE=1 SV=1 CANONICAL=A0A4X1T887-1" }, "locus": { "chromosome": "2", "start_pos": 66029722, "end_pos": 65959044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089214.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089214.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063453.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063453.2" } ] } }, { "isoform_ac": "F1SDA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887/entry#F1SDA0-1", "sequence": { "sequence": "MYSPYCLTQDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPDGAALTPPSPSFATTGASSANRFVSIGPRDGNFLNIPQQSQSWFL", "length": 502, "header": "tr|F1SDA0-1|F1SDA0_PIG Computationally mapped isoform of Nuclear factor 1 OS=Sus scrofa OX=9823 GN=NFIX PE=1 SV=4 CANONICAL=A0A4X1T887-1" }, "locus": { "chromosome": "2", "start_pos": 66056497, "end_pos": 65959044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015016.4", "url": "https://www.ensembl.org/id/ENSSSCT00000015016.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014611.4", "url": "https://www.ensembl.org/id/ENSSSCP00000014611.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT86", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT86" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523536", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523536", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K1B6-1", "protein_name": "Nuclear factor 1", "gene_name": "Nfix", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKTTSTAPDGAALTPPSPSFTTTGASSANRFVSIGSRDSNFLNIPQQSQSWFL", "length": 494 }, "evidence": [ { "id": "A0A4X1T887", "url": "https://omabrowser.org/oma/group/A0A4X1T887/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14938-1", "protein_name": "Nuclear factor 1 X-type", "gene_name": "NFIX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYSPYCLTQDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPDGAALTPPSPSFATTGASSANRFVSIGPRDGNFLNIPQQSQSWFL", "length": 502 }, "evidence": [ { "id": "A0A4X1T887", "url": "https://omabrowser.org/oma/group/A0A4X1T887/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T887", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T887" }, { "id": "PS51080", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51080" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CTF/NF-I", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 186, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 215, "end_pos": 217 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 412, "end_pos": 414 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1UL10-1", "uniprot_ac": "A0A5K1UL10", "uniprot_id": "A0A5K1UL10_PIG", "mass": { "chemical_mass": 66849.0, "monoisotopic_mass": 66849.0 }, "refseq": {}, "gene_names": [ { "name": "ELF1", "type": "recommended", "evidence": [ { "id": "A0A5K1UL10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ] } ], "protein_names": [ { "name": "E74 like ETS transcription factor 1", "type": "synonym", "evidence": [ { "id": "A0A5K1UL10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ELF1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10", "locus": { "chromosome": "11", "start_pos": 25900802, "end_pos": 25772316, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009440", "url": "https://www.ensembl.org/id/ENSSSCG00000009440" } ] } } ], "crossref": [ { "id": "A0A5K1UL10", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1UL10", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009440", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009440", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100512366", "url": "https://www.ncbi.nlm.nih.gov/gene/100512366", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512366", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512366", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DEKRMTT", "url": "https://omabrowser.org/oma/group/DEKRMTT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZTG6", "url": "https://www.orthodb.org/?gene=A0A286ZTG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A287A1F3", "url": "https://www.orthodb.org/?gene=A0A287A1F3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF156", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF156", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12310", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12310", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8939247", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939247", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZTG6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZTG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1F3", "url": "https://www.uniprot.org/uniprotkb/A0A287A1F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1F3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UL10-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RJ83", "url": "https://www.uniprot.org/uniprotkb/F1RJ83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RJ83-1", "url": "https://www.uniprot.org/uniprotkb/F1RJ83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSSSLIIKHHCSPKHVTLRKLLNFLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDEDDDDITLTVEASCHNGDETIETIEAAEALLNMDSPGPMLDEKRFNNNIFSSSEDDVIAPITHVSVTLDGIPEVMETQQVQETFAHSPGPSSPEQPKKKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKDLIYIDDEDPGSSIESSDPSLSSTTTSSRNPPSRSRGSSSPGTKGGATTVLKPGNSKAAKPKDPVEAAQPSEVLRTVQPTQTPYPTQLFRTIHVVQPVQTVPEGEATSSAQEETLSSSVQSIRTLQAPAQVPVVVSPGNQHLHTVTLQTVPITTVIASTDPSSGAGSQKFILQAIPSSQPMTVLKENVVLQSPKPGSPPSLVLSPAHVQQVLPSSVQSVCNGTVSVASSPSSFSASTPVVTFSPRNSQLVAHPPGTVITSVIKAQETKTHMQEGEKKEVEDSWKEGAEEPEQQPQPYVMVVSSSNGFTSQVAIKNELLEPSSF", "length": 617, "header": "tr|A0A5K1UL10-1|A0A5K1UL10_PIG Isoform 1 of E74 like ETS transcription factor 1 OS=Sus scrofa OX=9823 GN=ELF1 PE=3 SV=1 CANONICAL=A0A5K1UL10-1" }, "isoforms": [ { "isoform_ac": "A0A286ZTG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10/entry#A0A286ZTG6-1", "sequence": { "sequence": "MAAVVQQNDLVFEFASNVMEDEQQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDEDDDDITLTDNNIFSSSEDDVIAPITHVSVTLDGIPEVMETQQVQETFAHSPGPSSPEQPKKKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKDLIYIDDEDPGSSIESSDPSLSSTTTSSRNPPSRSRGSSSPGTKGGATTVLKPGNSKAAKPKDPVEAAQPSEVLRTVQPTQTPYPTQLFRTIHVVQPVQTVPEGEATSSAQEETLSSSVQSIRTLQAPAQVPVVVSPGNQHLHTVTLQTVPITTVIASTDPSSGAGSQKFILQAIPSSQPMTVLKENVVLQSPKPGSPPSLVLSPAHVQQVLPSSVQSVCNGTVSVASSPSSFSASTPVVTFSPRNSQLVAHPPGTVITSVIKAQETKTHMQEGEKKEVEDSWKEGAEEPEQQPQPYVMVVSSSNGFTSQVAIKNELLEPSSF", "length": 580, "header": "tr|A0A286ZTG6-1|A0A5K1UL10_PIG Computationally mapped isoform of E74 like ETS transcription factor 1 OS=Sus scrofa OX=9823 GN=ELF1 PE=3 SV=1 CANONICAL=A0A5K1UL10-1" }, "locus": { "chromosome": "11", "start_pos": 25895167, "end_pos": 25838326, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052396.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052396.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034754.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034754.2" } ] } }, { "isoform_ac": "A0A287A1F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10/entry#A0A287A1F3-1", "sequence": { "sequence": "MAAVVQQNDLVFEFASNVMEDEQQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDEDDDDITLTVEASCHNGDETIETIEAAEALLNMDSPGPMLDEKRFNNNIFSSSEDDVIAPITHVSVTLDGIPEVMETQQVQETFAHSPGPSSPEQPKKKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKDLIYIDDEDPGSSIESSDPSLSSTTTSSRNPPSRSRGSSSPGTKGGATTVLKPGNSKAAKPKDPVEAAQPSEVLRTVQPTQTPYPTQLFRTIHVVQPVQTVPEGEATSSAQEETLSSSVQSIRTLQAPAQVPVVVSPGNQHLHTVTLQTVPITTVIASTDPSSGAGSQKFILQAIPSSQPMTVLKENVVLQSPKPGSPPSLVLSPAHVQQVLPSSVQSVCNGTVSVASSPSSFSASTPVVTFSPRNSQLVAHPPGTVITSVIKAQETKTHMQEGEKKEVEDSWKEGAEEPEQQPQPYVMVVSSSNGFTSQVAIKNELLEPSSF", "length": 616, "header": "tr|A0A287A1F3-1|A0A5K1UL10_PIG Computationally mapped isoform of E74 like ETS transcription factor 1 OS=Sus scrofa OX=9823 GN=ELF1 PE=3 SV=2 CANONICAL=A0A5K1UL10-1" }, "locus": { "chromosome": "11", "start_pos": 25895167, "end_pos": 25838326, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065085.2", "url": "https://www.ensembl.org/id/ENSSSCT00000065085.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037752.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037752.2" } ] } }, { "isoform_ac": "A0A5K1UL10-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10/entry#A0A5K1UL10-1", "sequence": { "sequence": "MNSSSLIIKHHCSPKHVTLRKLLNFLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDEDDDDITLTVEASCHNGDETIETIEAAEALLNMDSPGPMLDEKRFNNNIFSSSEDDVIAPITHVSVTLDGIPEVMETQQVQETFAHSPGPSSPEQPKKKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKDLIYIDDEDPGSSIESSDPSLSSTTTSSRNPPSRSRGSSSPGTKGGATTVLKPGNSKAAKPKDPVEAAQPSEVLRTVQPTQTPYPTQLFRTIHVVQPVQTVPEGEATSSAQEETLSSSVQSIRTLQAPAQVPVVVSPGNQHLHTVTLQTVPITTVIASTDPSSGAGSQKFILQAIPSSQPMTVLKENVVLQSPKPGSPPSLVLSPAHVQQVLPSSVQSVCNGTVSVASSPSSFSASTPVVTFSPRNSQLVAHPPGTVITSVIKAQETKTHMQEGEKKEVEDSWKEGAEEPEQQPQPYVMVVSSSNGFTSQVAIKNELLEPSSF", "length": 617, "header": "tr|A0A5K1UL10-1|A0A5K1UL10_PIG Isoform 1 of E74 like ETS transcription factor 1 OS=Sus scrofa OX=9823 GN=ELF1 PE=3 SV=1 CANONICAL=A0A5K1UL10-1" }, "locus": { "chromosome": "11", "start_pos": 25895167, "end_pos": 25838387, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024675.3", "url": "https://www.ensembl.org/id/ENSSSCT00000024675.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023190.3", "url": "https://www.ensembl.org/id/ENSSSCP00000023190.3" } ] } }, { "isoform_ac": "F1RJ83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10/entry#F1RJ83-1", "sequence": { "sequence": "MISSFLNTCLEPWFVLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDEDDDDITLTVEASCHNGDETIETIEAAEALLNMDSPGPMLDEKRFNNNIFSSSEDDVIAPITHVSVTLDGIPEVMETQQVQETFAHSPGPSSPEQPKKKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKDLIYIDDEDPGSSIESSDPSLSSTTTSSRNPPSRSRGSSSPGTKGGATTVLKPGNSKAAKPKDPVEAAQPSEVLRTVQPTQTPYPTQLFRTIHVVQPVQTVPEGEATSSAQEETLSSSVQSIRTLQAPAQVPVVVSPGNQHLHTVTLQTVPITTVIASTDPSSGAGSQKFILQAIPSSQPMTVLKENVVLQSPKPGSPPSLVLSPAHVQQVLPSSVQSVCNGTVSVASSPSSFSASTPVVTFSPRNSQLVAHPPGTVITSVIKAQETKTHMQEGEKKEVEDSWKEGAEEPEQQPQPYVMVVSSSNGFTSQVAIKNELLEPSSF", "length": 607, "header": "tr|F1RJ83-1|A0A5K1UL10_PIG Computationally mapped isoform of E74 like ETS transcription factor 1 OS=Sus scrofa OX=9823 GN=ELF1 PE=3 SV=4 CANONICAL=A0A5K1UL10-1" }, "locus": { "chromosome": "11", "start_pos": 25895167, "end_pos": 25855254, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010347.4", "url": "https://www.ensembl.org/id/ENSSSCT00000010347.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010079.4", "url": "https://www.ensembl.org/id/ENSSSCP00000010079.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTG6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTG6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512366", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512366", "resource": "KEGG Pathway" }, { "id": "R-SSC-8939247", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939247", "resource": "Reactome", "description": "RUNX1 regulates transcription of genes involved in interleukin signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XCD1-1", "protein_name": "E74 like ETS transcription factor 1", "gene_name": "ELF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAVVQQNELVFEFASNVMEDEQQLGDPSIFPAVIVEHVPSGDLLNNYSGLTCVDEPSDMITENSLDVAEEQIIEDDDIPLTVETSCHNGDETMETIEAAEALLNMDSPGPMLDEKRITAMFGSTEDEDIVAPITHVSVTLDGIPEVVEVHQAPDPYSESPETPEFEQPKKKKGKKPKPSRPESPTTTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVYIDDEDASPSTESSDSSLLSTPVASRNQSSRSRASANTGTKGGSTTVLKTGNSKPAKLKEHVEVVQQQTPGLTSEVLRTMQSTQPVHPTQLFRTVHVMQPLHTLTEGHAAVTSNVPDETLNPSVQNIRTLQTPTQVPVVVSPGNQQLHTVTLQTVPLTTVIASTDPASAATPQKFILQAIPTSQPMTVLKENVMLQSQKPVSPPSSIVLSPAQVQQVLTSSVQTICNGTANVASSPSFTATTPVVTFSPSSSQVVAHPSGTVITSVIKATEAKQIGVQGVLKEDDGDKLDDPEQSEQRFQQQPFVMVVSSSNSFPSNIQAKQENEPLEPNSY", "length": 626 }, "evidence": [ { "id": "A0A5K1UL10", "url": "https://omabrowser.org/oma/group/A0A5K1UL10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0JN51-1", "protein_name": "ETS-related transcription factor Elf-1", "gene_name": "ELF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAVVQQNDLVFEFASNVMEDEQQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDEDEDDITLTVEASCHNGDETIETIEAAEALLNMDSPGPMLDEKRMNNSIFSSSEDDMVVAPVTHVSVTLDGIPEVMETQHVQETYAHSPGPSSPEQPKRKKGRKTKPPRPDSPTTTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKDLIYIDDEDPSCSIESSDPSLSSTATSSRNPASRSRASSSPGIKGGATTVLKPGNSKAAKPKDPMEPVQPSEALRTVQSTQAPYPTQLFRTIHVVQPVQAVPEAEAASSMPEETLNPSVPSIRTIQTPAQVPVVVSPGNQHLHTVTLQTVPITTVIASADPSSAAGSQKFILQAIPSSQPMTVLKENVVLQSQKPGSPPSIVLSPAHVQQVLTSSVPTVCNGTVSAASAPSFSATTPMVTFSHHSSQLVAHPPGTVITSVIKAQEAKTHIQEEVKKEVEDNEKQGTEDAEQQLQPYVMVVSNGFPSQAAIKNELLEPSSF", "length": 614 }, "evidence": [ { "id": "A0A5K1UL10", "url": "https://omabrowser.org/oma/group/A0A5K1UL10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3IGF7-1", "protein_name": "ETS-related transcription factor Elf-1 isoform X1", "gene_name": "Elf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAVVQQNDLVFEFASNVMEDEQQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHNGDETIETIEAAEALLNMDSPGPILDEKRINNNIFSSSEDDIVAPITHVSVTLDGIPEVMETQQVQEMNADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEDPSSSIESSDPSLSSTTTSSRNQANRSRVSSSPGIKGGATAVLKPGNSKAPKPKDPVEATQASEVLRTVQPSQAPYPTQLFQTVHVVQPVQAVSEGDTTITSTMQEETANSSVQSIRTIQASTQVPVVVSPGNQQLHTVTLQTVPLTTVIASTDPSSSASSQKFILQAIPSSQPMTVLKENVMLQSQKPGSPPSIVFSPTQVQQVLTSNVQSICNGAVSLDSSPSFSATTPVVTFSRSSQLVAHPPGTVITSVIKAQETKTLKHEADKKAEDHLNEDTEKTEQQPQPYLMVVSSSNGFPSQVAIKQNELLEPNSF", "length": 616 }, "evidence": [ { "id": "A0A5K1UL10", "url": "https://omabrowser.org/oma/group/A0A5K1UL10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3V9V2-1", "protein_name": "E74 like ETS transcription factor 1", "gene_name": "Elf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVVQQNDLVFDFASNVMEDEQQLGDPAIFPAVIVEHVPGADILNGYAGLACVEEPNDMITESSLDVAEEEIIEDDDDDITLTVEASCHNGDETIETIGAAEALLNMDSPGPVLDEKRINNNIFSSSEDDIVAPITHVSVTLDGIPEVMETQQVQESNADSPGASSPEQPKRKKGASLTCLGRRKTKPPRPDSPATTPNISVKKKSKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEGPSSSTESSDQSLSSTTTSSRNQANRTRMSSSPGIKGGATTILKPGNPKVAKPKDTVEVGQPSEVLRTVQPSQAPYPTQLFRTVHVVQPVQAIPEEATITSTMQEEAAGSSVQGIRTIQASTQVPVVVSPGNQQLHTVTLQTVPLTTVIASTDPSSGAGPQKFILQAIPSSQPMTVLKENVLLQSQKPGSPPSIVFSPTPVQQVLTGSVQSLGNGAVSMASPPNFSATAPVVTFSRSSQLAAHPPGTVITSVIKAQETKTPKAEVEKKAEGHLNGDPEEIEQQPQPYVMVVSSSNGFSSQVAITQNELLEPSSF", "length": 623 }, "evidence": [ { "id": "A0A5K1UL10", "url": "https://omabrowser.org/oma/group/A0A5K1UL10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P32519-1", "protein_name": "ETS-related transcription factor Elf-1", "gene_name": "ELF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVVQQNDLVFEFASNVMEDERQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIEAAEALLNMDSPGPMLDEKRINNNIFSSPEDDMVVAPVTHVSVTLDGIPEVMETQQVQEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDPSSSIESSDPSLSSSATSNRNQTSRSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVHVVQPVQAVPEGEAARTSTMQDETLNSSVQSIRTIQAPTQVPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPMTVLKENVMLQSQKAGSPPSIVLGPAQVQQVLTSNVQTICNGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQEVEKKESEDHLKENTEKTEQQPQPYVMVVSSSNGFTSQVAMKQNELLEPNSF", "length": 619 }, "evidence": [ { "id": "A0A5K1UL10", "url": "https://omabrowser.org/oma/group/A0A5K1UL10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60775-1", "protein_name": "ETS-related transcription factor Elf-1", "gene_name": "Elf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVVQQNDLVFEFASNGMEDEQQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHNGDETIETIEAAEALLNIDSPSPPVLDEKQINNNIFSSSEDDIVAPITHVSVTLDGIPEVMETQQVQETNADSPGASSPEQRKRKKGRKTKPPRPDSPTTTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEDPSSSIESSDQSLSSTTASSRNQANRSRVSSSPGIKGGAATILKPGNSKAANPKDPVEVGQPSEVLRTVQPSQAPYPTQLFRTVHVVQPVQAVPEEATIASTMQEEAANSSVPSIRTIQASTQVPVVVSPGNQQLHTVTVPLTTVIASIDPSSGAGSQKFILQTIPSSQPMTVLKENVMLQSQKPGSPSIVLSPTQVQQVLTSNVQSICNGAGSVASAPSFSATTPVVTFSRSSQLVAHPPGTVITSVIKAQETKTLKQEVEKKAEDDLNEDAEKSAQQPQPYVMVLSSSNGFSSQVAVKQNELLEPNSF", "length": 612 }, "evidence": [ { "id": "A0A5K1UL10", "url": "https://omabrowser.org/oma/group/A0A5K1UL10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UL10", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1UL10-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 617, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1UL10-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1UL10" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1UL10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UL10" }, { "id": "PS50061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ETS", "eco_id": "ECO_0000259", "start_pos": 208, "end_pos": 290, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 515, "end_pos": 517 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TRI7-1", "uniprot_ac": "A0A4X1TRI7", "uniprot_id": "A0A4X1TRI7_PIG", "mass": { "chemical_mass": 23329.0, "monoisotopic_mass": 23329.0 }, "refseq": { "ac": "NP_001090947", "name": "large ribosomal subunit protein eL14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090947" }, "gene_names": [ { "name": "RPL14", "type": "recommended", "evidence": [ { "id": "A0A4X1TRI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7" } ] }, { "name": "RPL14", "type": "synonym", "evidence": [ { "id": "NP_001090947", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090947" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein eL14", "type": "recommended", "evidence": [ { "id": "A0A4X1TRI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L14", "type": "synonym", "evidence": [ { "id": "NP_001090947", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090947" }, { "id": "A0A4X1TRI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein eL14", "type": "synonym", "evidence": [ { "id": "NP_001090947", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090947" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRI7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPL14", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7", "locus": { "chromosome": "13", "start_pos": 24699363, "end_pos": 24691893, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011272", "url": "https://www.ensembl.org/id/ENSSSCG00000011272" } ] } } ], "crossref": [ { "id": "A0A4X1TRI7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TRI7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011272", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011272", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23702", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23702", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100037994", "url": "https://www.ncbi.nlm.nih.gov/gene/100037994", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002784", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002784", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100037994", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100037994", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TRI7", "url": "https://www.orthodb.org/?gene=A0A4X1TRI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11127:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11127:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01929", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01929", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001090947", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090947", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZW72", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZW72-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TRI7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TRI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINAKWAATRWAKKIEAREKKAKMTDFDRYKVMKARKMRNRLIKLEVKKLQKAALLKASPKKALAKGAAAAAAAAAAKVPVKKITTAGKKAPAQKAPAQKAAGQKAAPPPKAQKVQKPPAQKAPAPKASGKKA", "length": 213, "header": "tr|A0A4X1TRI7-1|A0A4X1TRI7_PIG Isoform 1 of Large ribosomal subunit protein eL14 OS=Sus scrofa OX=9823 GN=RPL14 PE=3 SV=1 CANONICAL=A0A4X1TRI7-1" }, "isoforms": [ { "isoform_ac": "A0A286ZW72-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7/entry#A0A286ZW72-1", "sequence": { "sequence": "MLRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINAKWAATRWAKKIEAREKKAKMTDFDRYKVMKARKMRNRLIKLEVKKLQKAALLKASPKKALAKGAAAAAAAAAAKVPVKKITTAGKKAPAQKAPAQKAAGQKAAPPPKAQKVQKPPAQKAPAPKASGKKA", "length": 211, "header": "tr|A0A286ZW72-1|A0A4X1TRI7_PIG Computationally mapped isoform of Large ribosomal subunit protein eL14 OS=Sus scrofa OX=9823 GN=RPL14 PE=3 SV=2 CANONICAL=A0A4X1TRI7-1" }, "locus": { "chromosome": "13", "start_pos": 24698624, "end_pos": 24695630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056051.2", "url": "https://www.ensembl.org/id/ENSSSCT00000056051.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035865.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035865.2" } ] } }, { "isoform_ac": "A0A4X1TRI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7/entry#A0A4X1TRI7-1", "sequence": { "sequence": "MVFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINAKWAATRWAKKIEAREKKAKMTDFDRYKVMKARKMRNRLIKLEVKKLQKAALLKASPKKALAKGAAAAAAAAAAKVPVKKITTAGKKAPAQKAPAQKAAGQKAAPPPKAQKVQKPPAQKAPAPKASGKKA", "length": 213, "header": "tr|A0A4X1TRI7-1|A0A4X1TRI7_PIG Isoform 1 of Large ribosomal subunit protein eL14 OS=Sus scrofa OX=9823 GN=RPL14 PE=3 SV=1 CANONICAL=A0A4X1TRI7-1" }, "locus": { "chromosome": "13", "start_pos": 24698624, "end_pos": 24695225, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012340.4", "url": "https://www.ensembl.org/id/ENSSSCT00000012340.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012018.4", "url": "https://www.ensembl.org/id/ENSSSCP00000012018.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW72", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW72" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100037994", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100037994", "resource": "KEGG Pathway" }, { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRI7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRI7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRI7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7" } ], "pmid": "" }, { "name": "organelle membrane", "id": "GO:0031090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031090", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRI7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7" } ], "pmid": "" }, { "name": "large ribosomal subunit", "id": "GO:0015934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015934", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRI7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRI7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRI7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7" } ], "pmid": "" }, { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRI7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TRI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRI7" }, { "id": "PF01929", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01929" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein eL14", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 120, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SX99-1", "uniprot_ac": "A0A4X1SX99", "uniprot_id": "A0A4X1SX99_PIG", "mass": { "chemical_mass": 46468.0, "monoisotopic_mass": 46468.0 }, "refseq": { "ac": "XP_005670266", "name": "queuine tRNA-ribosyltransferase accessory subunit 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670266" }, "gene_names": [ { "name": "QTRT2", "type": "recommended", "evidence": [ { "id": "A0A4X1SX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ] }, { "name": "QTRT2", "type": "synonym", "evidence": [ { "id": "XP_005670266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670266" } ] } ], "protein_names": [ { "name": "Queuine tRNA-ribosyltransferase accessory subunit 2", "type": "recommended", "evidence": [ { "id": "A0A4X1SX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99/entry#names_and_taxonomy" } ] }, { "name": "Queuine tRNA-ribosyltransferase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A4X1SX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99/entry#names_and_taxonomy" } ] }, { "name": "queuine tRNA-ribosyltransferase accessory subunit 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005670266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670266" } ] } ], "function": [ { "annotation": "Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYH2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYH2#function" }, { "database": "HAMAP", "id": "MF_03043", "url": "https://hamap.expasy.org/signature/MF_03043" }, { "database": "UniProtKB", "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "QTRT2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99", "locus": { "chromosome": "13", "start_pos": 145853371, "end_pos": 145879845, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011912", "url": "https://www.ensembl.org/id/ENSSSCG00000011912" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011912", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011912", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100514190", "url": "https://www.ncbi.nlm.nih.gov/gene/100514190", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002616", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002616", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028592", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028592", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514190", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514190", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAGSRMK", "url": "https://omabrowser.org/oma/group/MAGSRMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SX99", "url": "https://www.orthodb.org/?gene=A0A4X1SX99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46064:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46064:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01702", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01702", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005670266", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670266", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZYH2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SX99-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLSLTKVVNGCRLGKIKNLGKTGDHTMDIPGCLLYTKTGSAPHLTHHTLNKIHGVPAMAQLTLSSLAEHHEVLAEYKEGVGKFIGMPESLLYCSLHDPVSPCPAGYVTNKSVSVWGVGGRVEMTTSKFMAIQQALQPDWFQCLSDGEATCDEATSIKRARKSVDRSLLFLDNCLKLQEESEVLQKSTIIGVIEGGDVMEERLRSARETAKRPVGGFLLDGFQGNPATLETRLHLLSSVTAELPEDKPRLISGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFSFDYQPNPEETLLQQNGTQEEIKCVDQTKKIKTTSCNQEMTSFEINLKEKKYQEDFDPLVRGCSCYCCKNHTRAYIHHLLVTNELLAGVLLMMHNFEHYFGFFHSIREALKSDHLAQLKELIHRQAS", "length": 415, "header": "tr|A0A4X1SX99-1|A0A4X1SX99_PIG Isoform 1 of Queuine tRNA-ribosyltransferase accessory subunit 2 OS=Sus scrofa OX=9823 GN=QTRT2 PE=3 SV=1 CANONICAL=A0A4X1SX99-1" }, "isoforms": [ { "isoform_ac": "A0A286ZYH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99/entry#A0A286ZYH2-1", "sequence": { "sequence": "MKLSLTKVVNGCRLGKIKNLGKTGDHTMDIPGCLLYTKTGSAPHLTHHTLNKIHGVPAMAQLTLSSLAEHHEVLAEYKEGVGKFIGMPESLLYCSLHDPVSPCPAGYVTNKSVSVWGVGGRVEMTTSKFMAIQQALQPDWFQCLSDGEATCDEATSIKRARKSVDRSLLFLDNCLKLQEESEVLQKSTIIGVIEGGDVMEERLRSARETAKRPVGGFLLDGFQGNPATLETRLHLLSSVTAELPEDKPRLISGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFSFDYQPNPEETLLQQNGTQEEIKCVDQTKKIKTTSCNQEMTSFEINLKEKKYQEDFDPLVRGCSCYCCKNHTRAYIHHLLVTNELLAGVLLMMHNFEHYFGFFHSIREALKSDHLAQLKELIHRGLFWTLLPAFQAVPAVQSTRNDSCDLTRLTFPWNVELAHCSSDRLAQGTLFIRPYGLSVTSLPRVKAIAY", "length": 482, "header": "tr|A0A286ZYH2-1|A0A4X1SX99_PIG Computationally mapped isoform of Queuine tRNA-ribosyltransferase accessory subunit 2 OS=Sus scrofa OX=9823 GN=QTRT2 PE=3 SV=1 CANONICAL=A0A4X1SX99-1" }, "locus": { "chromosome": "13", "start_pos": 145872991, "end_pos": 145854476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060467.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060467.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036509.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036509.1" } ] } }, { "isoform_ac": "A0A4X1SX99-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99/entry#A0A4X1SX99-1", "sequence": { "sequence": "MKLSLTKVVNGCRLGKIKNLGKTGDHTMDIPGCLLYTKTGSAPHLTHHTLNKIHGVPAMAQLTLSSLAEHHEVLAEYKEGVGKFIGMPESLLYCSLHDPVSPCPAGYVTNKSVSVWGVGGRVEMTTSKFMAIQQALQPDWFQCLSDGEATCDEATSIKRARKSVDRSLLFLDNCLKLQEESEVLQKSTIIGVIEGGDVMEERLRSARETAKRPVGGFLLDGFQGNPATLETRLHLLSSVTAELPEDKPRLISGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFSFDYQPNPEETLLQQNGTQEEIKCVDQTKKIKTTSCNQEMTSFEINLKEKKYQEDFDPLVRGCSCYCCKNHTRAYIHHLLVTNELLAGVLLMMHNFEHYFGFFHSIREALKSDHLAQLKELIHRQAS", "length": 415, "header": "tr|A0A4X1SX99-1|A0A4X1SX99_PIG Isoform 1 of Queuine tRNA-ribosyltransferase accessory subunit 2 OS=Sus scrofa OX=9823 GN=QTRT2 PE=3 SV=1 CANONICAL=A0A4X1SX99-1" }, "locus": { "chromosome": "13", "start_pos": 145872991, "end_pos": 145855149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013035.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013035.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012692.4", "url": "https://www.ensembl.org/id/ENSSSCP00000012692.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYH2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYH2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514190", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514190", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XXC1-1", "protein_name": "Queuine tRNA-ribosyltransferase accessory subunit 2", "gene_name": "QTRT2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRVKLCGAAGGRLGTLAGLGRSGAAALALPGCLLYTRTGTAPHLTLDTLREVSGVPPVAQLTLPTMAELHDVLAEYKEGAAKFIGMPDTVLYCSLQDPVAPCPSGYNTNKTVSLWSSSGRMEMTASKFMDIQRAIQPDWFQCIADGDTISGEVTRKRAKKSVDRSLSFLDACLQLLEKTPELQGSVMFGTIEGGDVLEERLRSARETAKRPVGGFLLDGFQGRAMAKETKMNLISSVTAELPEDKPRIIHGVGKPDEVLECIERGVDIFESFFPFQVTERGCALVFGYDYHSDPKAEAALKQNGAQDLEKNSPEEDQEEEVVKADPEMTPFEIFLKEKRYHDDFRPLLEGCTCYCCQRHTRAYLHHLLVSSELLAGVLLMMHNFQHYFSFFSAIRDALRDDKLDQLKKLIFRQALQGPENAKIDQ", "length": 425 }, "evidence": [ { "id": "A0A4X1SX99", "url": "https://omabrowser.org/oma/group/A0A4X1SX99/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B8ZXI1-1", "protein_name": "Queuine tRNA-ribosyltransferase accessory subunit 2", "gene_name": "Qtrt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLSLIKVVNGCRLGKIQNLGKAGDCTVDIPGCLLYTRTGSAPHLTHQTLRNIHGVPGIAQLTLSSLAEHHEVLAEYKKGVGSFIGMPESLFYCSLHDPVTPGPAGYVTSKSVSVWGFGGRVEMTVSKFMAIQEALQPDWFQCLSDGEASCAETTSIKRARKSVDRSLLFLDSCLRLQEESEVLQKSVIIGVIEGGDVMEERLRSARETAKRPVGGFLLDGFQGDPAVTETRLHLLSSVTAELPEDKPRLICGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFTFDCQLNPEETLLQQNGIQEKIKGLDQAKKIEATGCNQEMTSFEINLKEKKYQEDFDPLVRGCSCYCCKNHTRAYIHHLLMTNELLAGVLLMMHNFEHYFGFFCSIREALKNDTLAQLKELICRQMF", "length": 415 }, "evidence": [ { "id": "A0A4X1SX99", "url": "https://omabrowser.org/oma/group/A0A4X1SX99/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6Q3R4-1", "protein_name": "Queuine tRNA-ribosyltransferase accessory subunit 2", "gene_name": "QTRT2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNLTKVVNGCRLGKIKNLGKTGDCTMDIPGCLLYTKAGSAPHLTHHTLHKIHGVPAMAQLTLSSLAEHYEVLAEYKEGVGKFIGMPESLLYCSLHDPVSPCPAGYVTNKSVSVWGVGGRVEMTASKFMAIQQALQPDWFQCISDGEATCNEATSIKRARKSVDRSLLFLDNCLKLQEESEVLQKSSIIGVIEGGDVTEERLRSARETAKRPVGGFLLDGFQGNPATLETRLHLLSSVTAELPEDKPRLICGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFSFDYQPNPEETLLQQNGTQEEIKYVDQTKKSKTTSCNQEMTSFEINLKEKKYQEDFSPLVRGCSCYCCKNHTRAYIHHLLVTNELLAGVLLMMHNFEHYFGFFHSIREALKSDRLAQLKDLICRQAS", "length": 415 }, "evidence": [ { "id": "A0A4X1SX99", "url": "https://omabrowser.org/oma/group/A0A4X1SX99/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9H974-1", "protein_name": "Queuine tRNA-ribosyltransferase accessory subunit 2", "gene_name": "QTRT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLSLTKVVNGCRLGKIKNLGKTGDHTMDIPGCLLYTKTGSAPHLTHHTLHNIHGVPAMAQLTLSSLAEHHEVLTEYKEGVGKFIGMPESLLYCSLHDPVSPCPAGYVTNKSVSVWSVAGRVEMTVSKFMAIQKALQPDWFQCLSDGEVSCKEATSIKRVRKSVDRSLLFLDNCLRLQEESEVLQKSVIIGVIEGGDVMEERLRSARETAKRPVGGFLLDGFQGNPTTLEARLRLLSSVTAELPEDKPRLISGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFSFDYQPNPEETLLQQNGTQEEIKCMDQIKKIETTGCNQEITSFEINLKEKKYQEDFNPLVRGCSCYCCKNHTRAYIHHLLVTNELLAGVLLMMHNFEHYFGFFHYIREALKSDKLAQLKELIHRQAS", "length": 415 }, "evidence": [ { "id": "A0A4X1SX99", "url": "https://omabrowser.org/oma/group/A0A4X1SX99/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "pmid": "" }, { "name": "tRNA-guanosine(34) queuine transglycosylase activity", "id": "GO:0008479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008479", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "pmid": "" }, { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasmic side of mitochondrial outer membrane", "id": "GO:0032473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032473", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "pmid": "" }, { "name": "tRNA-guanine transglycosylase complex", "id": "GO:0120507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120507", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA wobble guanine modification", "id": "GO:0002099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002099", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "pmid": "" }, { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" }, { "id": "PF01702", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01702" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "tRNA-guanine(15) transglycosylase-like", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 413, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A286ZYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYH2#function" }, { "id": "A0A286ZYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYH2" }, { "id": "MF_03043", "database": "HAMAP", "url": "https://hamap.expasy.org/signature/MF_03043" }, { "id": "A0A4X1SX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99#function" }, { "id": "A0A4X1SX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "binding_site_uniprot": 351, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 351, "end_pos": 351, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A286ZYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYH2#function" }, { "id": "A0A286ZYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYH2" }, { "id": "MF_03043", "database": "HAMAP", "url": "https://hamap.expasy.org/signature/MF_03043" }, { "id": "A0A4X1SX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99#function" }, { "id": "A0A4X1SX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "binding_site_uniprot": 353, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 353, "end_pos": 353, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A286ZYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYH2#function" }, { "id": "A0A286ZYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYH2" }, { "id": "MF_03043", "database": "HAMAP", "url": "https://hamap.expasy.org/signature/MF_03043" }, { "id": "A0A4X1SX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99#function" }, { "id": "A0A4X1SX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "binding_site_uniprot": 356, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 356, "end_pos": 356, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A286ZYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYH2#function" }, { "id": "A0A286ZYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYH2" }, { "id": "MF_03043", "database": "HAMAP", "url": "https://hamap.expasy.org/signature/MF_03043" }, { "id": "A0A4X1SX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99#function" }, { "id": "A0A4X1SX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX99" } ], "binding_site_uniprot": 382, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 382, "end_pos": 382, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 358, "end_pos": 360 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1U3K0-1", "uniprot_ac": "A0A5K1U3K0", "uniprot_id": "A0A5K1U3K0_PIG", "mass": { "chemical_mass": 66789.0, "monoisotopic_mass": 66789.0 }, "refseq": { "ac": "XP_013850967", "name": "probable E3 ubiquitin-protein ligase DTX2 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850967" }, "gene_names": [ { "name": "DTX2", "type": "recommended", "evidence": [ { "id": "A0A5K1U3K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0" } ] }, { "name": "DTX2", "type": "synonym", "evidence": [ { "id": "XP_013850967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850967" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase", "type": "recommended", "evidence": [ { "id": "A0A5K1U3K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A5K1U3K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0/entry#names_and_taxonomy" } ] }, { "name": "probable E3 ubiquitin-protein ligase DTX2 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_013850967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850967" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U3K0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DTX2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0", "locus": { "chromosome": "3", "start_pos": 9888561, "end_pos": 9925850, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000025430", "url": "https://www.ensembl.org/id/ENSSSCG00000025430" } ] } } ], "crossref": [ { "id": "A0A5K1U3K0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1U3K0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000025430", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000025430", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09633", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09633", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16672", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16672", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100739198", "url": "https://www.ncbi.nlm.nih.gov/gene/100739198", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ICMEQLS", "url": "https://omabrowser.org/oma/group/ICMEQLS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12622", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12622", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2122948", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2122948", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013850967", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850967", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZZA7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1U3K0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1U3K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L5J4", "url": "https://www.uniprot.org/uniprotkb/I3L5J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L5J4-1", "url": "https://www.uniprot.org/uniprotkb/I3L5J4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMAPSPSLAQVYTSPVAVAVWEWQDGLGTWHPYSATVCSYIEQQFVQQKGQRFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGIVWEWLSDEGSWTPYEASICDYLEQQVARGNQLVDLAPLGYNYTVNYATHTQTNKTSSFCRSVRRQAGPPYPVTTIIAPPGHTGVACSCHQCLSGGGTGPVSGRYRHSMTSLPAYPVPQPPHRTAVVLGAHQAFAPYNKPSLSGARSAPRLNTTNPWAGAPPSLGNQPIYRSSLSHLGPQHQPLGPSTAGGASAYLPSGPASSPGSVPATVPVQMPKPSRVQQALAGMTSILMSAIGLPVCLSRAPQPASPPASCLASKSHSSVKRLRKMSMKGGPPKPEPEQVIKNYTEELKVAPDEDCIICMEKLSVASGYSDVTDSKTIGPMAVGRLAKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPRGKMEVFTFQVSLPGHEDCGTILIVYNIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTIGTSSTTGETDTVVWNEIHHKTEMDRNVTGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ", "length": 619, "header": "tr|A0A5K1U3K0-1|A0A5K1U3K0_PIG Isoform 1 of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=DTX2 PE=3 SV=1 CANONICAL=A0A5K1U3K0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0/entry#A0A286ZZA7-1", "sequence": { "sequence": "MLVHGRPLLPARSPGSIGNELENPAQSGLKLSEEAEGVLGKMAMAPSPSLAQVYTSPVAVAVWEWQDGLGTWHPYSATVCSYIEQQFVQQKGQRFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGIVWEWLSDEGSWTPYEASICDYLEQQVARGNQLVDLAPLGYNYTVNYATHTQTNKTSSFCRSVRRQAGPPYPVTTIIAPPGHTGVACSCHQCLSGGGTGPVSGRYRHSMTSLPAYPVPQPPHRTAVVLGAHQAFAPYNKPSLSGARSAPRLNTTNPWAGAPPSLGNQPIYRSSLSHLGPQHQPLGPSTAGGASAYLPSGPASSPGSVPATVPVQMPKPSRVQQALAGGPPKPEPEQVIKNYTEELKVAPDEDCIICMEKLSVASGYSDVTDSKTIGPMAVGRLAKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPRGKMEVFTFQVSLPGHEDCGTILIVYNIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTIGTSSTTGETDTVVWNEIHHKTEMDRNVTGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ", "length": 613, "header": "tr|A0A286ZZA7-1|A0A5K1U3K0_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=DTX2 PE=3 SV=2 CANONICAL=A0A5K1U3K0-1" }, "locus": { "chromosome": "3", "start_pos": 9915168, "end_pos": 9890707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040419.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040419.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036973.3", "url": "https://www.ensembl.org/id/ENSSSCP00000036973.3" } ] } }, { "isoform_ac": "A0A5K1U3K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0/entry#A0A5K1U3K0-1", "sequence": { "sequence": "MAMAPSPSLAQVYTSPVAVAVWEWQDGLGTWHPYSATVCSYIEQQFVQQKGQRFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGIVWEWLSDEGSWTPYEASICDYLEQQVARGNQLVDLAPLGYNYTVNYATHTQTNKTSSFCRSVRRQAGPPYPVTTIIAPPGHTGVACSCHQCLSGGGTGPVSGRYRHSMTSLPAYPVPQPPHRTAVVLGAHQAFAPYNKPSLSGARSAPRLNTTNPWAGAPPSLGNQPIYRSSLSHLGPQHQPLGPSTAGGASAYLPSGPASSPGSVPATVPVQMPKPSRVQQALAGMTSILMSAIGLPVCLSRAPQPASPPASCLASKSHSSVKRLRKMSMKGGPPKPEPEQVIKNYTEELKVAPDEDCIICMEKLSVASGYSDVTDSKTIGPMAVGRLAKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPRGKMEVFTFQVSLPGHEDCGTILIVYNIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTIGTSSTTGETDTVVWNEIHHKTEMDRNVTGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ", "length": 619, "header": "tr|A0A5K1U3K0-1|A0A5K1U3K0_PIG Isoform 1 of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=DTX2 PE=3 SV=1 CANONICAL=A0A5K1U3K0-1" }, "locus": { "chromosome": "3", "start_pos": 9912665, "end_pos": 9890707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027187.4", "url": "https://www.ensembl.org/id/ENSSSCT00000027187.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021696.2", "url": "https://www.ensembl.org/id/ENSSSCP00000021696.2" } ] } }, { "isoform_ac": "I3L5J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0/entry#I3L5J4-1", "sequence": { "sequence": "MLVHGRPLLPARSPGSIGNELENPAQSGLKLSEEAEGVLGKMAMAPSPSLAQVYTSPVAVAVWEWQDGLGTWHPYSATVCSYIEQQFVQQKGQRFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGIVWEWLSDEGSWTPYEASICDYLEQQVARGNQLVDLAPLGYNYTVNYATHTQTNKTSSFCRSVRRQAGPPYPVTTIIAPPGHTGVACSCHQCLSGGGTGPVSGRYRHSMTSLPAYPVPQPPHRTAVVLGAHQAFAPYNKPSLSGARSAPRLNTTNPWAGAPPSLGNQPIYRSSLSHLGPQHQPLGPSTAGGASAYLPSGPASSPGSVPATVPVQMPKPSRVQQALAGMTSILMSAIGLPVCLSRAPQPASPPASCLASKSHSSVKRLRKMSMKGGPPKPEPEQVIKNYTEELKVAPDEDCIICMEKLSVASGYSDVTDSKTIGPMAVGRLAKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPRGKMEVFTFQVSLPGHEDCGTILIVYNIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTIGTSSTTGETDTVVWNEIHHKTEMDRNVTGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ", "length": 660, "header": "tr|I3L5J4-1|I3L5J4_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase OS=Sus scrofa OX=9823 GN=DTX2 PE=3 SV=4 CANONICAL=A0A5K1U3K0-1" }, "locus": { "chromosome": "3", "start_pos": 9915168, "end_pos": 9890707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025080.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025080.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019293.4", "url": "https://www.ensembl.org/id/ENSSSCP00000019293.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZA7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZA7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2122948", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2122948", "resource": "Reactome", "description": "Activated NOTCH1 Transmits Signal to the Nucleus" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MNG7-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "DTX2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAMAPSPSLAQVYTSPVAVAVWEWQDGLGTWHPYSAAVCSYIEQQFVQQKGQRFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFAQHSAPGRGIVWEWLGDDNSWTAYEASVCDYLEQQVAQGNQLVDLAPLGYNYTVNYATHTQTNKTSSFCRSVRRQAGPPYPVTTVIAPPGHTGVACSCHQCLSGGTTGPVSGRYRHSMTNLPAYPVPQPPHRTAIVWGTHQAFAPYNKPSLSGARSAPRLNTTNPWAGAPPSLGSAPLCRSSLSHLASQHQPSGPSATGAASASLPSGPVSSPRSVPATVPVKMPKPSRVQQALAGMTSILMSAIGLPVCLSRAPQPASPPASCLASKSHSSVKRLRKMSMKGGSPKPEPEQVIRNYTEELKTAPEEDCIICMEKLSVASGYSDVTDSKTFGPMAVGCLAKCSHTFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPRGKMEVFTFQMSLPGHEDCGTILIVYNIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNVTGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ", "length": 619 }, "evidence": [ { "id": "A0A5K1U3K0", "url": "https://omabrowser.org/oma/group/A0A5K1U3K0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TTJ2-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "DTX2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAQGAGSSSAGPPGAPVSIPGHSSSTAVVVWEWQDEFGRWRPYRGDVCKFIEQGFQASQQKGRRSGSGLVSSSISLGHADAGLAPYVIDIPSLTQFRQDTGTMRAVRRHLFPRDSAAEQGIIWEWQNDERGWFPYEMNVCVFLEQAHASSHQRVDLGPLGYNYEVDLVAQVQTNKTTRFCRSVRRRVDNPYPVTAALAPVHTGTGCSCQQCWLNGGTGPITTRYRHSMTNFPNSSAAPQVSGRTTSVSSSGVGFVPYNKPALSGARSAPRLNAQSSWAFPQAGGAVGPSTGLSTSNGVSALNLPVKMSKPSKLNQALAGMTAILMSAAGLPVHLTCVPQAASTHKATKKHSSVKEGRKVSKKGWWRSLAASVMGLMTAAPTDPEAVVRKYLVEVKGTPVDEDCIICMEKLASPSGYSDTCECRTIKPEMVGRLTNCQHSFHMLCVLAMYSNGNKDGSLQCPSCKTIYGEKTGTQPKGKMEVSTFPQSLPGHRDCGTIQIVYHISRGIQGPEHPNPGMPYTARGFPRYCYLPDNEKGRKVLELLKVAWNRRLIFTVGTSNTTGESNTVVWNEIHHKTEMDTNLSGHGYPDPNYLDNVLAELAAQGVTEDCLRK", "length": 614 }, "evidence": [ { "id": "A0A5K1U3K0", "url": "https://omabrowser.org/oma/group/A0A5K1U3K0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3V658-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Dtx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMAPSSSLPQVYPSHVVVAVWEWQDGLGIWHPYSATVCSFIEQQFIRQRGQHFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRSVRRHLFSQNSAPGQGIVWEWLGDDGSWIAYEARICDYLEQQVARGIQVVDLAPLGYNYTVNYATLTQTNKTSSFCRSVRRQVGPVYPVTSDIAVPRQMGLICFCQQCLHGSGTGPVSGRYRHSMTNLPAYPAPQAPHRTATVSGAHQAFAPYNKPSLSGARSAPRLNTTSPWGATPPVPGNQSLLHSSLSHLGPQLLPSGPSTSSGTSASFPSGPSSSSPGSAPTTVPVQMPKPSRVQQALAGMTSVLSAIGLPVCLSRAPRPTGPPASRPTSKSHSSVKRLRKMSVKEGAPKPEPEQVIRKYTEELKVAPEEDCIICMEKLSVASGYSDVTDSKALGPMVVGRLTKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPWGKMEVFRFHMSLPGHEDCGTILIVYNIPHGIQGPEHPSPGKPFTARGFPRQCYLPDSPQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNVTGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ", "length": 619 }, "evidence": [ { "id": "A0A5K1U3K0", "url": "https://omabrowser.org/oma/group/A0A5K1U3K0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86UW9-1", "protein_name": "Probable E3 ubiquitin-protein ligase DTX2", "gene_name": "DTX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGSWTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPYPVTTIIAPPGHTGVACSCHQCLSGSRTGPVSGRYRHSMTNLPAYPVPQHPPHRTASVFGTHQAFAPYNKPSLSGARSAPRLNTTNAWGAAPPSLGSQPLYRSSLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQMPKPSRVQQALAGMTSVLMSAIGLPVCLSRAPQPTSPPASRLASKSHGSVKRLRKMSVKGATPKPEPEPEQVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ", "length": 622 }, "evidence": [ { "id": "A0A5K1U3K0", "url": "https://omabrowser.org/oma/group/A0A5K1U3K0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R3P2-1", "protein_name": "Probable E3 ubiquitin-protein ligase DTX2", "gene_name": "Dtx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMAPSSSLPQVYPSHVVVAVWEWQDGLGIWHPYSATVCSFIEQHFVRQRGQHFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQNTGTMRSVRRHLFSQNSAPGQGIVWEWLGDDGSWVAYEARICDYLEQQVARGIQVVDLAPLGYNYTVNYATLTQTNKTSSFCRSVRRQVGPVYPVTSDIAVPRQMGLICFCQQCLHGSGTGPVSGRYRHSMTNLPAYPAPQAPHRTTTVSGAHQAFAPYNKPSLSGARSAPRLNTTNPWAAAPPVAGNQSLFHSSLSHLGPQLLPSGPSTSSGASASFPSGPSSSSPGSAPTTVPVQMPKASRVQQALAGMTSVLSAIGLPVCLSRAPRPTGPPASRPASKSHSSVKRLRKMSVKEGAPKPEPEQVIRKYTEELKVAPEEDCIICMEKLAVASGYSDMTDSKALGPMVVGRLTKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPWGKMEVFRFQMSLPGHEDCGTILIVYNIPHGIQGPEHPSPGKPFTARGFPRQCYLPDSPQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNVTGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ", "length": 619 }, "evidence": [ { "id": "A0A5K1U3K0", "url": "https://omabrowser.org/oma/group/A0A5K1U3K0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U3K0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U3K0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U3K0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U3K0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U3K0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U3K0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U3K0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U3K0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-1912357", "name": "ITCH ubiquitinates DTX", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1912357", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1912357" } ] }, { "id": "R-SSC-1980125", "name": "ITCH binds DTX", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1980125", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1980125" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1U3K0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 619, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1U3K0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1U3K0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1U3K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 409, "end_pos": 470, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5K1U3K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U3K0" }, { "id": "PS50918", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50918" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WWE", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 97, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 587, "end_pos": 589 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TAR0-1", "uniprot_ac": "A0A4X1TAR0", "uniprot_id": "A0A4X1TAR0_PIG", "mass": { "chemical_mass": 17087.0, "monoisotopic_mass": 17087.0 }, "refseq": {}, "gene_names": [ { "name": "PTP4A1", "type": "recommended", "evidence": [ { "id": "A0A4X1TAR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0" } ] } ], "protein_names": [ { "name": "Protein tyrosine phosphatase 4A1", "type": "synonym", "evidence": [ { "id": "A0A4X1TAR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAR0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PTP4A1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0", "locus": { "chromosome": "1", "start_pos": 45180289, "end_pos": 45170468, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000025941", "url": "https://www.ensembl.org/id/ENSSSCG00000025941" } ] } } ], "crossref": [ { "id": "A0A4X1TAR0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TAR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000025941", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000025941", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22785", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22785", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZZR6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TAR0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TAR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FF63", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FF63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREDPGCCIAVHCVAGLGRKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ", "length": 148, "header": "tr|A0A4X1TAR0-1|A0A4X1TAR0_PIG Isoform 1 of Protein tyrosine phosphatase 4A1 OS=Sus scrofa OX=9823 GN=PTP4A1 PE=1 SV=1 CANONICAL=A0A4X1TAR0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0/entry#A0A286ZZR6-1", "sequence": { "sequence": "MNRPAPVEVTYKNMRFLITHNPTNATLNKFIEDWPFDDGAPPSNQIVDDWLSLVKIKFREDPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ", "length": 139, "header": "tr|A0A286ZZR6-1|A0A4X1TAR0_PIG Computationally mapped isoform of Protein tyrosine phosphatase 4A1 OS=Sus scrofa OX=9823 GN=PTP4A1 PE=1 SV=1 CANONICAL=A0A4X1TAR0-1" }, "locus": { "chromosome": "1", "start_pos": 45178461, "end_pos": 45173978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092386.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092386.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079982.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079982.1" } ] } }, { "isoform_ac": "A0A4X1TAR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0/entry#A0A4X1TAR0-1", "sequence": { "sequence": "MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREDPGCCIAVHCVAGLGRKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ", "length": 148, "header": "tr|A0A4X1TAR0-1|A0A4X1TAR0_PIG Isoform 1 of Protein tyrosine phosphatase 4A1 OS=Sus scrofa OX=9823 GN=PTP4A1 PE=1 SV=1 CANONICAL=A0A4X1TAR0-1" }, "locus": { "chromosome": "1", "start_pos": 45178461, "end_pos": 45173969, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026265.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026265.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020245.2", "url": "https://www.ensembl.org/id/ENSSSCP00000020245.2" } ] } }, { "isoform_ac": "A0A8W4FF63-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0/entry#A0A8W4FF63-1", "sequence": { "sequence": "MSDSFGSVYLFLFLNCFHSPLLELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREDPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ", "length": 160, "header": "tr|A0A8W4FF63-1|A0A4X1TAR0_PIG Computationally mapped isoform of Protein tyrosine phosphatase 4A1 OS=Sus scrofa OX=9823 GN=PTP4A1 PE=1 SV=1 CANONICAL=A0A4X1TAR0-1" }, "locus": { "chromosome": "1", "start_pos": 45178461, "end_pos": 45174890, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092901.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092901.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078069.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078069.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZR6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZR6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAR0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAR0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAR0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TAR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAR0" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 110, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1STM2-1", "uniprot_ac": "A0A4X1STM2", "uniprot_id": "A0A4X1STM2_PIG", "mass": { "chemical_mass": 116873.0, "monoisotopic_mass": 116873.0 }, "refseq": {}, "gene_names": [ { "name": "NNT", "type": "recommended", "evidence": [ { "id": "A0A4X1STM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2" } ] } ], "protein_names": [ { "name": "NAD(P) transhydrogenase, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A4X1STM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2/entry#names_and_taxonomy" } ] }, { "name": "7.1.1.1", "type": "synonym", "evidence": [ { "id": "A0A4X1STM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2/entry#names_and_taxonomy" } ] }, { "name": "Nicotinamide nucleotide transhydrogenase", "type": "synonym", "evidence": [ { "id": "A0A4X1STM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1U9", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U9#function" }, { "database": "UniProtKB", "id": "ARBA00054910", "url": "https://www.uniprot.org/uniprotkb/ARBA00054910#function" }, { "database": "UniProtKB", "id": "A0A4X1STM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2#function" }, { "database": "UniProtKB", "id": "F1SMG3", "url": "https://www.uniprot.org/uniprotkb/F1SMG3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NNT", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2", "locus": { "chromosome": "16", "start_pos": 28250961, "end_pos": 28157318, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016877", "url": "https://www.ensembl.org/id/ENSSSCG00000016877" } ] } } ], "crossref": [ { "id": "A0A4X1STM2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1STM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016877", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016877", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100526144", "url": "https://www.ncbi.nlm.nih.gov/gene/100526144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100526144", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100526144", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EQCREVD", "url": "https://omabrowser.org/oma/group/EQCREVD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1SMG3", "url": "https://www.orthodb.org/?gene=F1SMG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10160:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10160:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01262", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01262", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02233", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02233", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05222", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05222", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12769", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12769", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "47992", "url": "https://www.rhea-db.org/rhea/47992", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZZT0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1U9", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1STM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1STM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEH6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SMG3", "url": "https://www.uniprot.org/uniprotkb/F1SMG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SMG3-1", "url": "https://www.uniprot.org/uniprotkb/F1SMG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTQEVASEILTYLQGNWAFGKLGAPRNMANLLKTVVTGCSCPFRSSWGSCKVLPGKKDFLRTFHTHQALWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYRAAGAQIQGVKEVLASDLVVKVRAPMLNPTLGVHEADLLKTSATLISFIYPAQNPDLLNKLSKRKTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYVHKGVTHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFEVKDDFDFGTMGHVIRGTVVMKDGEVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMTSASVYTAGLTGILGLGLAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGHLYPSTTSQGLAALATFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLAALYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPCPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIVEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLIAYGKLQGILKSAPLLLPGRHLLNAGLLAASVGGIIPFMVDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLSEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK", "length": 1113, "header": "tr|A0A4X1STM2-1|A0A4X1STM2_PIG Isoform 1 of NAD(P) transhydrogenase, mitochondrial OS=Sus scrofa OX=9823 GN=NNT PE=1 SV=1 CANONICAL=A0A4X1STM2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2/entry#A0A286ZZT0-1", "sequence": { "sequence": "MANLLKTVVTGCSCPFRSSWGSCKVLPGKKDFLRTFHTHQALWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYRAAGAQIQGVKEVLASDLVVKVRAPMLNPTLGVHEADLLKTSATLISFIYPAQNPDLLNKLSKRKTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYVHKGVTHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFEVKDDFDFGTMGHVIRGTVVMKDGEVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMTSASVYTADSGILIYIKYIEW", "length": 494, "header": "tr|A0A286ZZT0-1|A0A4X1STM2_PIG Computationally mapped isoform of NAD(P) transhydrogenase, mitochondrial OS=Sus scrofa OX=9823 GN=NNT PE=1 SV=3 CANONICAL=A0A4X1STM2-1" }, "locus": { "chromosome": "16", "start_pos": 28200113, "end_pos": 28162513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062719.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062719.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037201.3", "url": "https://www.ensembl.org/id/ENSSSCP00000037201.3" } ] } }, { "isoform_ac": "A0A287B1U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2/entry#A0A287B1U9-1", "sequence": { "sequence": "MLLASLSFLTYLQGNWAFGKLGAPRNMANLLKTVVTGCSCPFRSSWGSCKVLPGKKDFLRTFHTHQALWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYRAAGAQIQGVKEVLASDLVVKVRAPMLNPTLGVHEADLLKTSATLISFIYPAQNPDLLNKLSKRKTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYVHKGVTHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFEVKDDFDFGTMGHVIRGTVVMKDGEVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMTSASVYTAGLTGILGLGLAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGHLYPSTTSQGLAALATFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLAALYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPCPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIVEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLIAYGKLQGILKSAPLLLPGRHLLNAGLLAASVGGIIPFMVDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLSEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK", "length": 1112, "header": "tr|A0A287B1U9-1|A0A4X1STM2_PIG Computationally mapped isoform of NAD(P) transhydrogenase, mitochondrial OS=Sus scrofa OX=9823 GN=NNT PE=1 SV=1 CANONICAL=A0A4X1STM2-1" }, "locus": { "chromosome": "16", "start_pos": 28247904, "end_pos": 28158650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046689.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046689.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050214.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050214.2" } ] } }, { "isoform_ac": "A0A4X1STM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2/entry#A0A4X1STM2-1", "sequence": { "sequence": "MTQEVASEILTYLQGNWAFGKLGAPRNMANLLKTVVTGCSCPFRSSWGSCKVLPGKKDFLRTFHTHQALWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYRAAGAQIQGVKEVLASDLVVKVRAPMLNPTLGVHEADLLKTSATLISFIYPAQNPDLLNKLSKRKTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYVHKGVTHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFEVKDDFDFGTMGHVIRGTVVMKDGEVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMTSASVYTAGLTGILGLGLAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGHLYPSTTSQGLAALATFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLAALYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPCPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIVEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLIAYGKLQGILKSAPLLLPGRHLLNAGLLAASVGGIIPFMVDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLSEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK", "length": 1113, "header": "tr|A0A4X1STM2-1|A0A4X1STM2_PIG Isoform 1 of NAD(P) transhydrogenase, mitochondrial OS=Sus scrofa OX=9823 GN=NNT PE=1 SV=1 CANONICAL=A0A4X1STM2-1" }, "locus": { "chromosome": "16", "start_pos": 28247904, "end_pos": 28158377, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049053.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049053.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046278.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046278.2" } ] } }, { "isoform_ac": "A0A8W4FEH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2/entry#A0A8W4FEH6-1", "sequence": { "sequence": "MANLLKTVVTGCSCPFRSSWGSCKVLPGKKDFLRTFHTHQALWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYRAAGAQIQGVKEVLASDLVVKVRAPMLNPTLGVHEADLLKTSATLISFIYPAQNPDLLNKLSKRKTTVLAMDQVPRVTIAQGYDALSSMANIAGAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYVHKGVTHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFEVKDDFDFGTMGHVIRGTVVMKDGEVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMTSASVYTAGLTGILGLGLAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGHLYPSTTSQGLAALATFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLAALYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPCPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIVEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLIAYGKLQGILKSAPLLLPGRHLLNAGLLAASVGGIIPFMVDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLSEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK", "length": 1027, "header": "tr|A0A8W4FEH6-1|A0A4X1STM2_PIG Computationally mapped isoform of NAD(P) transhydrogenase, mitochondrial OS=Sus scrofa OX=9823 GN=NNT PE=1 SV=1 CANONICAL=A0A4X1STM2-1" }, "locus": { "chromosome": "16", "start_pos": 28247904, "end_pos": 28162513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093049.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093049.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077824.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077824.1" } ] } }, { "isoform_ac": "F1SMG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2/entry#F1SMG3-1", "sequence": { "sequence": "MANLLKTVVTGCSCPFRSSWGSCKVLPGKKDFLRTFHTHQALWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYRAAGAQIQGVKEVLASDLVVKVRAPMLNPTLGVHEADLLKTSATLISFIYPAQNPDLLNKLSKRKTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYVHKGVTHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFEVKDDFDFGTMGHVIRGTVVMKDGEVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMTSASVYTAGLTGILGLGLAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGHLYPSTTSQGLAALATFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLAALYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPCPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIVEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLIAYGKLQGILKSAPLLLPGRHLLNAGLLAASVGGIIPFMVDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLSEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK", "length": 1086, "header": "tr|F1SMG3-1|F1SMG3_PIG Computationally mapped isoform of NAD(P) transhydrogenase, mitochondrial OS=Sus scrofa OX=9823 GN=NNT PE=1 SV=2 CANONICAL=A0A4X1STM2-1" }, "locus": { "chromosome": "16", "start_pos": 28247904, "end_pos": 28162513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018381.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018381.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017885.3", "url": "https://www.ensembl.org/id/ENSSSCP00000017885.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 547, "start_aa": "Thr", "end_pos": 547, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr547", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZT0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZT0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100526144", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100526144", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YP51-1", "protein_name": "NAD(P) transhydrogenase, mitochondrial", "gene_name": "NNT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPTSAIPYVARSQLGGWGDMASLLRVAVSGCSVPVLGAVLPPKVHSTKMPCLRMFGTHQVLWSQAAPKPGIPYKQLTVGVPKEIFENEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYREVGAKIQGTKEVLASDVIVKVRAPMHNPALGVHEADLFKTAPTLISFIYPAQNPDLLKKLAEKRTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKVLIIGGGVAGLASAGAAKSMGAVVRGFDTRAAALEQFKSLGAEPLEVDIKESGEGQGGYAKEMSKEFIEAEMKLFAKQCQDVDIIITTALIPGKKAPVLFKKDMIESMKEGSVVVDLAAEAGGNIETTKPGELYVHKGVTHIGYTDLPSRMATQASTLYSNNIIKLLKAISPDKENFYFDPKDQFDYGTLDHVIRGTVVMKDGKVIFPAPPPNNIPQGAPVKPKTVAELEAEKAATITPFRKTMTSASVYTTGLASMLGLGIVSPNTAFTQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGTYLPENAPQSLAVLSAFISSINIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPGGVFVGGYAAALSGGYSIEQMMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPSPELLAQMSGAMALGGTIGLTIAKRIQITDLPQLVAAFHSLVGLAAVLTCVAEYMIEYPHFATDPAANLTKIVAYLGTYIGGVTFSGSLVAYGKLQGILNSAPLLLPGRHALNAGLLAASFGGMIPYMIDPSYTTGITCLGSVSALSAIMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEITGTHTEINVDNAIEMIKEANSIIITPGYGLCAAKAQYPIADLVKMLREQGKNVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINEDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKARESYQS", "length": 1105 }, "evidence": [ { "id": "A0A4X1STM2", "url": "https://omabrowser.org/oma/group/A0A4X1STM2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P11024-1", "protein_name": "NAD(P) transhydrogenase, mitochondrial", "gene_name": "NNT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MANLLKTVVTGCSCPFLSNLGSCKVLPGKKNFLRTFHTHRILWCSAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYRAAGAQIQGAKEVLASDLVVKVRAPMLNPTLGVHEADLLKTSGTLISFIYPAQNPDLLNKLSKRKTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPILFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYVHKGITHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFEVKDDFDFGTMGHVIRGTVVMKDGQVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMTSASVYTAGLTGILGLGIAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGHLYPSTTSQGLAALATFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLASLYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPCPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIIEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLVAYGKLQGILKSAPLLLPGRHLLNAGLLAGSVGGIIPFMMDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLSEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK", "length": 1086 }, "evidence": [ { "id": "A0A4X1STM2", "url": "https://omabrowser.org/oma/group/A0A4X1STM2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q13423-1", "protein_name": "NAD(P) transhydrogenase, mitochondrial", "gene_name": "NNT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANLLKTVVTGCSCPLLSNLGSCKGLRVKKDFLRTFYTHQELWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQNLVKQGFNVVVESGAGEASKFSDDHYRVAGAQIQGAKEVLASDLVVKVRAPMVNPTLGVHEADLLKTSGTLISFIYPAQNPELLNKLSQRKTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYIHKGITHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFDVKDDFDFGTMGHVIRGTVVMKDGKVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMSTASAYTAGLTGILGLGIAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLALMGGHLYPSTTSQGLAALAAFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLAALYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGVLKPGPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIIEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLIAYGKLQGLLKSAPLLLPGRHLLNAGLLAASVGGIIPFMVDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLTEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK", "length": 1086 }, "evidence": [ { "id": "A0A4X1STM2", "url": "https://omabrowser.org/oma/group/A0A4X1STM2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55F30-1", "protein_name": "NAD(P) transhydrogenase, mitochondrial", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLLSLITKKVSPNQIGTILKTKSSSSSSLLNNIRYSTLNNSNKLIHPISTSTRFNCNFNESNKNVLNKNNFEPSNKVISIKRNVTNRLFYSTLKDQTGSVLPTTPNQGITSIDMALELTKDAKGIPFEQLTIGIPTEVYQNEKRVSMTPENVGVLVKKGYKVLVEEGAGKGAKFSDAKYIEAGAKITTAANLFKKTDILLKVRGPQFNTNLGKHEVEMMKEGATVISFLSPAQNAETLKLLSQKKANAIAVDCIPRISRAQVFDGLSSMANIAGYKAVMEASNYFGRFFGGAITAAGRVQPAKVLVIGAGVAGLSAIGTAKNIGAIVRAFDTRSVTKEQVESLGGEFLEVKIKESGEGSGGYAKHMSKEYIEAEMALFERQCKEVDIVITTALIPGVPAPKLITKQMVDQMKPGSVIVDLAAETGGNCELTKPGEAYNYNGVSIIGFTDLPSKMATQSSTLYSNNITKFLLSLGNDKDGFKLDFTDEVHRGSTVTYNGTLIWPAPKKPVPVTPPSPSTPVSNKEKVESNLVKEETSLFNKTLKSALGATAAMCGAVAMSMGLPADFMVNLTTFSLAALIGYKVVWGVTPALHSPLMSITNAISGIVAVAGLHLMGGGYIPSTGGQLLASAAVFMASINIAGGFTITKRMLDMFKLPTDKPTYEYLYGIPSLGFLAAYLSTVGSGGPALTQLAYLASSIMCILSISGLSSAKSSRLGNILGMGGIAIGLGATVASLGVSSALLAQMAGVGLVGGGIGYLFSKRVNFTELPQLTAAFHSFVGMAAVLASGASLLADYSNFAALDTIHKSSVYLGALIGGITFTGSVVAYAKLQGHIGKWKVPSKPYHVPNRHLVNTGLALANVATFATFLSTTNPTLGLACLGATTILSFIQGHLLTAAINGPDMPVVVTVLNSYSGWALVAEGFMLDSSLLNIVGAIVGSSGAILSYIMCKAMNRNLMSVILGGVGTSSMGKGEAMKITGTHTEINVDQASEMITNSKNILIVPGYGMVVSKSQYPVAEMVKTLIEKGHNVKFGIHPVAGRLPGHLNICLSEAKVPYDIVFEMEEINPEMKDIDLAIVIGANDTVNSASVEDPNSIIAGMPVIEVWKAKHCIVMKRSLTNAGYADIQNPVFYKPNTSMLLGDATNTCKELANKIDKHYNSSH", "length": 1163 }, "evidence": [ { "id": "A0A4X1STM2", "url": "https://omabrowser.org/oma/group/A0A4X1STM2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2" } ], "pmid": "" }, { "name": "proton-translocating NAD(P)+ transhydrogenase activity", "id": "GO:0008750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008750", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "reactive oxygen species metabolic process", "id": "GO:0072593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072593", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2" } ], "pmid": "" }, { "name": "NADPH regeneration", "id": "GO:0006740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006740", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1036, "end_pos": 1038, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 763, "end_pos": 765, "annotation": "n_glycosylation_sequon" }, { "start_pos": 908, "end_pos": 910, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "47992", "name": "", "equation": "NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "47992", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47992" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1STM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2" }, { "id": "SM01003", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal", "eco_id": "ECO_0000259", "start_pos": 87, "end_pos": 226, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1STM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STM2" }, { "id": "SM01002", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding", "eco_id": "ECO_0000259", "start_pos": 235, "end_pos": 399, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 547 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1036, "end_pos": 1038 }, { "start_pos": 418, "end_pos": 420 }, { "start_pos": 763, "end_pos": 765 }, { "start_pos": 908, "end_pos": 910 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TH36-1", "uniprot_ac": "A0A4X1TH36", "uniprot_id": "A0A4X1TH36_PIG", "mass": { "chemical_mass": 40548.0, "monoisotopic_mass": 40548.0 }, "refseq": { "ac": "XP_020945068", "name": "protein-L-isoaspartate O-methyltransferase domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945068" }, "gene_names": [ { "name": "PCMTD1", "type": "recommended", "evidence": [ { "id": "A0A4X1TH36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36" } ] }, { "name": "PCMTD1", "type": "synonym", "evidence": [ { "id": "XP_020945068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945068" } ] } ], "protein_names": [ { "name": "Protein-L-isoaspartate O-methyltransferase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A4X1TH36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36/entry#names_and_taxonomy" } ] }, { "name": "protein-L-isoaspartate O-methyltransferase domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020945068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945068" } ] } ], "function": [ { "annotation": "Substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Specifically binds to the methyltransferase cofactor S-adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but does not display methyltransferase activity. May provide an alternate maintenance pathway for modified proteins by acting as a damage-specific E3 ubiquitin ligase adaptor protein.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH36", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36#function" }, { "database": "UniProtKB", "id": "ARBA00045904", "url": "https://www.uniprot.org/uniprotkb/ARBA00045904#function" }, { "database": "UniProtKB", "id": "A0A287BAK7", "url": "https://www.uniprot.org/uniprotkb/A0A287BAK7#function" }, { "database": "UniProtKB", "id": "A0A287A1G0", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G0#function" }, { "database": "UniProtKB", "id": "F1RSF3", "url": "https://www.uniprot.org/uniprotkb/F1RSF3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH36", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PCMTD1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36", "locus": { "chromosome": "4", "start_pos": 78162963, "end_pos": 78098999, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006267", "url": "https://www.ensembl.org/id/ENSSSCG00000006267" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006267", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006267", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100153676", "url": "https://www.ncbi.nlm.nih.gov/gene/100153676", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153676", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153676", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QSTWDSR", "url": "https://omabrowser.org/oma/group/QSTWDSR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287BAK7", "url": "https://www.orthodb.org/?gene=A0A287BAK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TH36", "url": "https://www.orthodb.org/?gene=A0A4X1TH36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11579", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11579", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11579:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11579:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01135", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020945068", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945068", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A1G0", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BAK7", "url": "https://www.uniprot.org/uniprotkb/A0A287BAK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BAK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BAK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TH36", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TH36-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSF3", "url": "https://www.uniprot.org/uniprotkb/F1RSF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSF3-1", "url": "https://www.uniprot.org/uniprotkb/F1RSF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVSNQLIPQPLDSEEDEKMEEDKEEEEKDHGEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFREK", "length": 356, "header": "tr|A0A4X1TH36-1|A0A4X1TH36_PIG Isoform 1 of Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=PCMTD1 PE=1 SV=1 CANONICAL=A0A4X1TH36-1" }, "isoforms": [ { "isoform_ac": "A0A287A1G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36/entry#A0A287A1G0-1", "sequence": { "sequence": "MGRPLALLTSASSRATHAPAAVRACPVSDGSEAAALGLPQPASGPRPSPLRWRRWRRRRRRRRTCCCGGGGAGCGGARQVPAPHLRPPRRAGRPPRRRFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVSNQLIPQPLDSEEDEKMEEDKEEEEKDHGEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFREK", "length": 317, "header": "tr|A0A287A1G0-1|A0A4X1TH36_PIG Computationally mapped isoform of Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=PCMTD1 PE=1 SV=1 CANONICAL=A0A4X1TH36-1" }, "locus": { "chromosome": "4", "start_pos": 78160256, "end_pos": 78098999, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047670.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047670.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037562.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037562.2" } ] } }, { "isoform_ac": "A0A287BAK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36/entry#A0A287BAK7-1", "sequence": { "sequence": "MGKLAKALLWTKSSVHLKMKIIQHAHERKPQPRFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVSNQLIPQPLDSEEDEKMEEDKEEEEKDHGEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFREK", "length": 252, "header": "tr|A0A287BAK7-1|A0A4X1TH36_PIG Computationally mapped isoform of Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=PCMTD1 PE=1 SV=1 CANONICAL=A0A4X1TH36-1" }, "locus": { "chromosome": "4", "start_pos": 78160256, "end_pos": 78145673, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054128.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054128.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041773.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041773.2" } ] } }, { "isoform_ac": "A0A4X1TH36-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36/entry#A0A4X1TH36-1", "sequence": { "sequence": "MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVSNQLIPQPLDSEEDEKMEEDKEEEEKDHGEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFREK", "length": 356, "header": "tr|A0A4X1TH36-1|A0A4X1TH36_PIG Isoform 1 of Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=PCMTD1 PE=1 SV=1 CANONICAL=A0A4X1TH36-1" }, "locus": { "chromosome": "4", "start_pos": 78160256, "end_pos": 78124956, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044050.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044050.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048171.1", "url": "https://www.ensembl.org/id/ENSSSCP00000048171.1" } ] } }, { "isoform_ac": "F1RSF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36/entry#F1RSF3-1", "sequence": { "sequence": "MGLSFIQMWWNMPRRNWRASSKIVIALITAYQKNFMGKLAKALLWTKSSVHLKMKIIQHAHERKPQPRFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVSNQLIPQPLDSEEDEKMEEDKEEEEKDHGEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFREK", "length": 287, "header": "tr|F1RSF3-1|A0A4X1TH36_PIG Computationally mapped isoform of Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=PCMTD1 PE=1 SV=3 CANONICAL=A0A4X1TH36-1" }, "locus": { "chromosome": "4", "start_pos": 78160256, "end_pos": 78139404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006866.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006866.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006680.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006680.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G0", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153676", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153676", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5YBY9-1", "protein_name": "Protein-L-isoaspartate O-methyltransferase domain-containing protein 1", "gene_name": "Pcmtd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "GWEVFPGPVDWRLSSEGASRVRSSQEVVATRAVQLPWSRVAGRAPPSRAGAGGRCARPVGCLCGAPPAAGLPLLWPGGLPPTQARDAGAGTGLWGQSGRCCCVSVFCVFGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGTPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDSKEEEEKDHSEAMKREEPPQNLLREKIMKLPLPESLKAYLTYFRDK", "length": 364 }, "evidence": [ { "id": "A0A4X1TH36", "url": "https://omabrowser.org/oma/group/A0A4X1TH36/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2VDP2-1", "protein_name": "Protein-L-isoaspartate O-methyltransferase domain-containing protein 1", "gene_name": "PCMTD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDKEEEEKEPGEALKPEEPPQNLLREKIMKLPLPESLKAYLTYFREK", "length": 356 }, "evidence": [ { "id": "A0A4X1TH36", "url": "https://omabrowser.org/oma/group/A0A4X1TH36/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P59913-1", "protein_name": "Protein-L-isoaspartate O-methyltransferase domain-containing protein 1", "gene_name": "Pcmtd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGTPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDSKEEEEKEHIEAMKREEPPQNLLREKIMKLPLPESLKAYLTYFRDK", "length": 357 }, "evidence": [ { "id": "A0A4X1TH36", "url": "https://omabrowser.org/oma/group/A0A4X1TH36/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5ZMR3-1", "protein_name": "Protein-L-isoaspartate O-methyltransferase domain-containing protein 1", "gene_name": "PCMTD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGGAVSAGEDNDDLIDNLKEAQYIRTESVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKYSDSFDKFEFCEPAFVVGNCLEIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQILRTGQNTWESKNILAVSFAPLVQPNRNDNGKHDTVGLPPCAVRNLQDLARIYIRRTLRNFINEEMKAKGIAQKAPPKRKRRRCRRRRINTYVFVGNQLIPQPLDSEEDERMEDDNKEEEDKDHSEALKPEEPPRNLLREKIMSLPLPESLKAYLTYYREK", "length": 358 }, "evidence": [ { "id": "A0A4X1TH36", "url": "https://omabrowser.org/oma/group/A0A4X1TH36/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q96MG8-1", "protein_name": "Protein-L-isoaspartate O-methyltransferase domain-containing protein 1", "gene_name": "PCMTD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFRDK", "length": 357 }, "evidence": [ { "id": "A0A4X1TH36", "url": "https://omabrowser.org/oma/group/A0A4X1TH36/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH36", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH36", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36" } ], "pmid": "" }, { "name": "Cul5-RING ubiquitin ligase complex", "id": "GO:0031466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031466", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH36", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-L-isoaspartate (D-aspartate) O-methyltransferase activity", "id": "GO:0004719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004719", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH36", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH36", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH36", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH36", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RLP2-1", "uniprot_ac": "A0A5G2RLP2", "uniprot_id": "A0A5G2RLP2_PIG", "mass": { "chemical_mass": 60947.0, "monoisotopic_mass": 60947.0 }, "refseq": {}, "gene_names": [ { "name": "LGALS3BP", "type": "recommended", "evidence": [ { "id": "A0A5G2RLP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2" } ] } ], "protein_names": [ { "name": "Galectin-3-binding protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RLP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2/entry#names_and_taxonomy" } ] }, { "name": "Lectin galactoside-binding soluble 3-binding protein", "type": "synonym", "evidence": [ { "id": "A0A5G2RLP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A604", "url": "https://www.uniprot.org/uniprotkb/A0A287A604#function" }, { "database": "UniProtKB", "id": "ARBA00024860", "url": "https://www.uniprot.org/uniprotkb/ARBA00024860#function" }, { "database": "UniProtKB", "id": "A0A5G2RLP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LGALS3BP", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2", "locus": { "chromosome": "12", "start_pos": 3222711, "end_pos": 3212432, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036383", "url": "https://www.ensembl.org/id/ENSSSCG00000036383" } ] } } ], "crossref": [ { "id": "A0A5G2RLP2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RLP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000036383", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036383", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051481", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051481", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LMLCGGR", "url": "https://omabrowser.org/oma/group/LMLCGGR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24410", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24410", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24410:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24410:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A604", "url": "https://www.uniprot.org/uniprotkb/A0A287A604", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A604-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A604-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPLWLLWMWLLVTGTQGVKDGDMRLAGGEADNEGRVEIFYSGQWGVCDSLWDLTDASVVCRALGFRNVTKALGGAAFGPGSGPIMLDEVECEGTELSLADCRSLGWMQSDCGHNEDASVICTKETRGVHTLDLSGEIPEALERIFESQTGCDLFIQVKAKEDELGLCAHKLILSANPEAHGLWKEPSSRVTMEVDAECVPVVRDYIRYLYSRRVDVSLASVQCFHQLASAYGAQQLQSFCAHLFAVLIPQDRSFRAPLDLYAYALASRDPVLEEVCVQFLTWNFEALTQAEAWPSVPAALLHSLLARSELVVSSELALLAALDVWSRERGASHGEVEGLVEKVRFPMMPPRDLFQLQFNLSLYRSHEALFQRKTLQALEFHTVPFQLLAQYRGLNLSGDAYRPRLYTSPRWSANQTASAYSPYESFQTPKHPSFLFQDSSVSWSFVYLPTVQSCWNYGFSCSPDEPPLLGLSKTSSLDPTIGYENKALMLCEGSFVADIAAFKDTKALIPSALGTNSSRSAAFFPCPAGFFSSFQAVIRPFYLTNSSGVD", "length": 551, "header": "tr|A0A5G2RLP2-1|A0A5G2RLP2_PIG Isoform 1 of Galectin-3-binding protein OS=Sus scrofa OX=9823 GN=LGALS3BP PE=4 SV=1 CANONICAL=A0A5G2RLP2-1" }, "isoforms": [ { "isoform_ac": "A0A287A604-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2/entry#A0A287A604-1", "sequence": { "sequence": "MGTVCDSLWDLTDASVVCRALGFRNVTKALGGAAFGPGSGPIMLDEVECEGTELSLADCRSLGWMQSDCGHNEDASVICTKETRGVHTLDLSGEIPEALERIFESQTGCDLFIQVKAKEDELGLCAHKLILSANPEAHGLWKEPSSRVTMEVDAECVPVVRDYIRYLYSRRVDVSLASVQCFHQLASAYGAQQLQSFCAHLFAVLIPQDRSFRAPLDLYAYALASRDPVLEEVCVQFLTWNFEALTQAEAWPSVPAALLHSLLARSELVVSSELALLAALDVWSRERGASHGEVEGLVEKVRFPMMPPRDLFQLQFNLSLYRSHEALFQRKTLQALEFHTVPFQLLAQYRGLNLSGDAYRPRLYTSPRWSANQTASAYSPYESFQTPKHPSFLFQDSSVSWSFVYLPTVQSCWNYGFSCSPDEPPLLGLSKTSSLDPTIGYENKALMLCEGSFVADIAAFKDTKALIPSALGTNSSRSAAFFPCPAGFFSSFQAVIRPFYLTNSSGVD", "length": 508, "header": "tr|A0A287A604-1|A0A5G2RLP2_PIG Computationally mapped isoform of Galectin-3-binding protein OS=Sus scrofa OX=9823 GN=LGALS3BP PE=4 SV=2 CANONICAL=A0A5G2RLP2-1" }, "locus": { "chromosome": "12", "start_pos": 3222308, "end_pos": 3212570, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049917.2", "url": "https://www.ensembl.org/id/ENSSSCT00000049917.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039404.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039404.2" } ] } }, { "isoform_ac": "A0A5G2RLP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2/entry#A0A5G2RLP2-1", "sequence": { "sequence": "MAPLWLLWMWLLVTGTQGVKDGDMRLAGGEADNEGRVEIFYSGQWGVCDSLWDLTDASVVCRALGFRNVTKALGGAAFGPGSGPIMLDEVECEGTELSLADCRSLGWMQSDCGHNEDASVICTKETRGVHTLDLSGEIPEALERIFESQTGCDLFIQVKAKEDELGLCAHKLILSANPEAHGLWKEPSSRVTMEVDAECVPVVRDYIRYLYSRRVDVSLASVQCFHQLASAYGAQQLQSFCAHLFAVLIPQDRSFRAPLDLYAYALASRDPVLEEVCVQFLTWNFEALTQAEAWPSVPAALLHSLLARSELVVSSELALLAALDVWSRERGASHGEVEGLVEKVRFPMMPPRDLFQLQFNLSLYRSHEALFQRKTLQALEFHTVPFQLLAQYRGLNLSGDAYRPRLYTSPRWSANQTASAYSPYESFQTPKHPSFLFQDSSVSWSFVYLPTVQSCWNYGFSCSPDEPPLLGLSKTSSLDPTIGYENKALMLCEGSFVADIAAFKDTKALIPSALGTNSSRSAAFFPCPAGFFSSFQAVIRPFYLTNSSGVD", "length": 551, "header": "tr|A0A5G2RLP2-1|A0A5G2RLP2_PIG Isoform 1 of Galectin-3-binding protein OS=Sus scrofa OX=9823 GN=LGALS3BP PE=4 SV=1 CANONICAL=A0A5G2RLP2-1" }, "locus": { "chromosome": "12", "start_pos": 3222308, "end_pos": 3213968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070957.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070957.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073298.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073298.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A604", "url": "https://www.uniprot.org/uniprotkb/A0A287A604" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A7E3W2-1", "protein_name": "Galectin-3-binding protein", "gene_name": "LGALS3BP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPLRLFWIWLLVVGTRGVKDGDMRLADGGSANQGRVEIYYNGQWGTVCENMWDLTDASVVCRALGFQNATEALGGAAFGPGYGPIMLDEVRCTGTEPSLANCSSLGWMRSNCRHDKDASVICTNETRGVYTLDLSGELPAALEQIFESQKGCDLFITVKVREEDEIAMCAHKLILSTNPEAHGLWKEPGSRVTMEVDAECVPVVKDFIRYLYSRRIDVSLSSVKCLHKLASAYQAKQLQSYCGHLFAILIPQDPSFWTPLELYAYALATRDPVLEEICVQFLAWNFGALTQAEAWPSVPPALLQGLLSRTELVVPSELVLLLAVDKWSQERRTSHKEVEALVGQVRFPMMPPQDLFSLQFNLSLYWSHEALFQKKILQALEFHTVPFELLAQYWGLNLTEGTYQPRLYTSPTWSQSVMSSSYNPSRSFQTPQHPSFLFHDSSVSWSFVYLPTLQSCWNYGFSCSSDDPPLLALSKSSYSKSNPTIGYENRALLHCEGSFVVDVIDFKGWKALVPSALATNSSRSTSLFPCPSGVFSRFQVVIRPFYLTNSTDMD", "length": 555 }, "evidence": [ { "id": "A0A5G2RLP2", "url": "https://omabrowser.org/oma/group/A0A5G2RLP2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H3E4-1", "protein_name": "Galectin-3-binding protein", "gene_name": "Lgals3bp", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALLWLFSLWLLVPGTQGTEDGDMRLVNGASASEGRVEIFYRGQWGTVCDNLWNILDANVVCRALGYENATRALGRAAFGPGQGPVMLDEVECAGTEPSLANCSSLGWLKSRCGHEKDAGVVCSNETESMHILDLSGDLPDALGQIFDSQQGCDLFIQVTGQGHRDLTLCAHKLILNTNSEAQALWHAEGSSVIMRVDVDCMPVVRDFLRYFYSRRIEVTMSSVKCLHKLASAYGATQLRDYCSRLFATLLPEDPTFHTPLELYEYAQATRDSVLEELCVQFLAWNFEPLTQVEAWLSVPTTLLQALLSKSELAVSSELDLLKAVDQWSAESGASHAEVEGLVEQVRFPMMLPQQLFELQFNLSLYQGHQALFQRKTMEALEFHTVPFPVLAKYRGLNLTENTYKPRLYTSSTWSTLVTDRSSRSQGAQVYGYYSYGYDSVSRYSPYRSFQTPQHPSFLFTDKLISWSATYLPTVQSCWNYGFSCTSDELPVLGLTKSSYSEPMIGYENKALMLCGGHSVVDVTNFAGSKAPVPSALDTNSSKISSLFPCTSGAFSGFRVVIRPFYLTNSTDLD", "length": 574 }, "evidence": [ { "id": "A0A5G2RLP2", "url": "https://omabrowser.org/oma/group/A0A5G2RLP2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O70513-1", "protein_name": "Galectin-3-binding protein", "gene_name": "Lgals3bp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLWLLSVFLLVPGTQGAKDGDMRLVNGASASEGRVEIFYRGRWGTVCDNLWNLLDAHVVCRALGYENATQALSRAAFGPGKGPIMLDEVECTGNESSLANCSSLGWMVSHCGHEKDAGVVCSNDSRGIHILDLSGELPDALGQIFDSQQDCDLFIQVTGQGHGDLSLCAHTLILRTNPEAQALWQVVGSSVIMRVDAECMPVVRDFLRYFYSRRIEVSMSSVKCLHKLASAYGATELQGYCGRLFVTLLPQDPTFHTPLELYEYAQATGDSVLEDLCVQFLAWNFEPLTQAEAWLSVPNALIQALLPKSELAVSSELDLLKAVDQWSTATGASHGDVERLVEQIRFPMMLPQELFELQFNLSLYQGHQALFQRKTMEALEFHTVPLKVLAKYRSLNLTEDVYKPRLYTSSTWSSLLMAGAWSTQSYKYRQFYTYNYGSQSRYSSYQNFQTPQHPSFLFKDKLISWSATYLPTIQSCWNYGFSCTSDELPVLGLTTSSYSDPTIGYENKALILCGGYSVVDVTTFIGSKAPIPGTQETNSSKTPSLFPCASGAFSSFRVVIRPFYLTNSTDTE", "length": 574 }, "evidence": [ { "id": "A0A5G2RLP2", "url": "https://omabrowser.org/oma/group/A0A5G2RLP2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q07797-1", "protein_name": "Galectin-3-binding protein", "gene_name": "Lgals3bp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLWLLSVFLLVPGTQGTEDGDMRLVNGASANEGRVEIFYRGRWGTVCDNLWNLLDAHVVCRALGYENATQALGRAAFGPGKGPIMLDEVECTGTESSLASCRSLGWMVSRCGHEKDAGVVCSNDTTGLHILDLSGELSDALGQIFDSQQGCDLFIQVTGQGYEDLSLCAHTLILRTNPEAQALWQVVGSSVIMRVDAECMPVVRDFLRYFYSRRIEVSMSSVKCLHKLASAYGATELQDYCGRLFATLLPQDPTFHTPLDLYAYARATGDSMLEDLCVQFLAWNFEPLTQSESWSAVPTTLIQALLPKSELAVSSELDLLKAVDQWSTETIASHEDIERLVEQVRFPMMLPQELFELQFNLSLYQDHQALFQRKTMQALEFHTVPVEVLAKYKGLNLTEDTYKPRLYTSSTWSSLVMASTWRAQRYEYNRYNQLYTYGYGSVARYNSYQSFQTPQHPSFLFKDKQISWSATYLPTMQSCWNYGFSCTSNELPVLGLTTSSYSNPTIGYENRVLILCGGYSVVDVTSFEGSKAPIPTALDTNSSKTPSLFPCASGAFSSFRVVIRPFYLTNSTDMV", "length": 577 }, "evidence": [ { "id": "A0A5G2RLP2", "url": "https://omabrowser.org/oma/group/A0A5G2RLP2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" }, { "start_pos": 546, "end_pos": 548, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RLP2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 551, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RLP2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RLP2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RLP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 152, "end_pos": 219, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RLP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLP2" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 123, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 360, "end_pos": 362 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 517, "end_pos": 519 }, { "start_pos": 546, "end_pos": 548 }, { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SSJ6-1", "uniprot_ac": "A0A4X1SSJ6", "uniprot_id": "A0A4X1SSJ6_PIG", "mass": { "chemical_mass": 10845.0, "monoisotopic_mass": 10845.0 }, "refseq": {}, "gene_names": [ { "name": "ATP5MG", "type": "recommended", "evidence": [ { "id": "A0A4X1SSJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6" } ] } ], "protein_names": [ { "name": "ATP synthase F(0) complex subunit g, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A4X1SSJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6/entry#names_and_taxonomy" } ] }, { "name": "ATPase subunit g", "type": "synonym", "evidence": [ { "id": "A0A4X1SSJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Subunit g, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A725", "url": "https://www.uniprot.org/uniprotkb/A0A287A725#function" }, { "database": "UniProtKB", "id": "PIRNR017835", "url": "https://www.uniprot.org/uniprotkb/PIRNR017835#function" }, { "database": "UniProtKB", "id": "A0A4X1SSJ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6#function" }, { "database": "UniProtKB", "id": "A0A8W4FGD2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGD2#function" }, { "database": "UniProtKB", "id": "F1SAK7", "url": "https://www.uniprot.org/uniprotkb/F1SAK7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SSJ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ATP5MG", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6", "locus": { "chromosome": "9", "start_pos": 45717036, "end_pos": 45706534, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000052280", "url": "https://www.ensembl.org/id/ENSSSCG00000052280" } ] } } ], "crossref": [ { "id": "A0A4X1SSJ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SSJ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000046892", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000046892", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "6ZMR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6ZMR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6ZNA", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6ZNA&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9BXU", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9BXU&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9BYK", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9BYK&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR006808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016702", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016702", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TEVCMWF", "url": "https://omabrowser.org/oma/group/TEVCMWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12386", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12386", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00006zmr", "url": "https://www.rcsb.org/structure/pdb_00006zmr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006zna", "url": "https://www.rcsb.org/structure/pdb_00006zna", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009bxu", "url": "https://www.rcsb.org/structure/pdb_00009bxu", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009byk", "url": "https://www.rcsb.org/structure/pdb_00009byk", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6ZMR", "url": "https://www.rcsb.org/structure/6ZMR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6ZNA", "url": "https://www.rcsb.org/structure/6ZNA", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9BXU", "url": "https://www.rcsb.org/structure/9BXU", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9BYK", "url": "https://www.rcsb.org/structure/9BYK", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF04718", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04718", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-163210", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8949613", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8949613", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A725", "url": "https://www.uniprot.org/uniprotkb/A0A287A725", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A725-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A725-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SSJ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SSJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGD2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SAK7", "url": "https://www.uniprot.org/uniprotkb/F1SAK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SAK7-1", "url": "https://www.uniprot.org/uniprotkb/F1SAK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLNFTDECPCLAAVTYSKPRLATFWHYAKVELVPPTPAEIPTAIQSLKKIVNSAQTGSFKQLTVKEALLNGLVATEVLMWFYVGEIIGKRGIIGYDV", "length": 98, "header": "tr|A0A4X1SSJ6-1|A0A4X1SSJ6_PIG Isoform 1 of ATP synthase F(0) complex subunit g, mitochondrial OS=Sus scrofa OX=9823 GN=ATP5MG PE=1 SV=1 CANONICAL=A0A4X1SSJ6-1" }, "isoforms": [ { "isoform_ac": "A0A287A725-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6/entry#A0A287A725-1", "sequence": { "sequence": "MAQFVRNLAEKAPVLVNAAVTYSKPRLATFWHYAKVELVPPTPAEIPTAIQSLKKIVNSAQTGSFKQLTVKEALLNGLVATEVLMWFYVGEIIGKAALAAHGSSQVRG", "length": 108, "header": "tr|A0A287A725-1|A0A4X1SSJ6_PIG Computationally mapped isoform of ATP synthase F(0) complex subunit g, mitochondrial OS=Sus scrofa OX=9823 GN=ATP5MG PE=1 SV=3 CANONICAL=A0A4X1SSJ6-1" }, "locus": { "chromosome": "9", "start_pos": 45715165, "end_pos": 45706733, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038200.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038200.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039776.3", "url": "https://www.ensembl.org/id/ENSSSCP00000039776.3" } ] } }, { "isoform_ac": "A0A4X1SSJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6/entry#A0A4X1SSJ6-1", "sequence": { "sequence": "MKLNFTDECPCLAAVTYSKPRLATFWHYAKVELVPPTPAEIPTAIQSLKKIVNSAQTGSFKQLTVKEALLNGLVATEVLMWFYVGEIIGKRGIIGYDV", "length": 98, "header": "tr|A0A4X1SSJ6-1|A0A4X1SSJ6_PIG Isoform 1 of ATP synthase F(0) complex subunit g, mitochondrial OS=Sus scrofa OX=9823 GN=ATP5MG PE=1 SV=1 CANONICAL=A0A4X1SSJ6-1" }, "locus": { "chromosome": "9", "start_pos": 45714412, "end_pos": 45707324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102611.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102611.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075451.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075451.1" } ] } }, { "isoform_ac": "A0A8W4FGD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6/entry#A0A8W4FGD2-1", "sequence": { "sequence": "LIASCLIELPCDTAAVTYSKPRLATFWHYAKVELVPPTPAEIPTAIQSLKKIVNSAQTGSFKQLTVKEALLNGLVATEVLMWFYVGEIIGKRGIIGYDV", "length": 99, "header": "tr|A0A8W4FGD2-1|A0A4X1SSJ6_PIG Computationally mapped isoform of ATP synthase F(0) complex subunit g, mitochondrial OS=Sus scrofa OX=9823 GN=ATP5MG PE=1 SV=1 CANONICAL=A0A4X1SSJ6-1" }, "locus": { "chromosome": "9", "start_pos": 45714412, "end_pos": 45712624, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091675.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091675.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078372.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078372.1" } ] } }, { "isoform_ac": "F1SAK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6/entry#F1SAK7-1", "sequence": { "sequence": "MAQFVRNLAEKAPVLVNAAVTYSKPRLATFWHYAKVELVPPTPAEIPTAIQSLKKIVNSAQTGSFKQLTVKEALLNGLVATEVLMWFYVGEIIARAQHGIPTI", "length": 103, "header": "tr|F1SAK7-1|F1SAK7_PIG Computationally mapped isoform of ATP synthase F(0) complex subunit g, mitochondrial OS=Sus scrofa OX=9823 GN=ATP5MG PE=1 SV=2 CANONICAL=A0A4X1SSJ6-1" }, "locus": { "chromosome": "9", "start_pos": 45716032, "end_pos": 45706733, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104253.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104253.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079091.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079091.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SAK7", "url": "https://www.uniprot.org/uniprotkb/F1SAK7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Structure of the dimeric ATP synthase from bovine mitochondria.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2020", "authors": "Spikes Tobias E, Montgomery Martin G, Walker John E", "evidence": [ { "database": "UniProtKB", "id": "F1SAK7", "url": "https://www.uniprot.org/uniprotkb/F1SAK7" } ], "reference": [ { "type": "PubMed", "id": "32900941", "url": "https://glygen.org/publication/PubMed/32900941" } ] } ], "pathway": [ { "id": "R-SSC-163210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163210", "resource": "Reactome", "description": "Formation of ATP by chemiosmotic coupling" }, { "id": "R-SSC-8949613", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8949613", "resource": "Reactome", "description": "Cristae formation" }, { "id": "R-SSC-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NIL3-1", "protein_name": "ATP synthase subunit g", "gene_name": "ATP5L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAQAAQKLVQRLTTRGPQLLSAAVAYSKPRLATFWYYAKVELAPPTPGEIPKAIDSMKAMVRSFQSGRLAQLTVREALRNGLVATEVLMWFYIGEIIGKRGLIGYNV", "length": 107 }, "evidence": [ { "id": "A0A4X1SSJ6", "url": "https://omabrowser.org/oma/group/A0A4X1SSJ6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O75964-1", "protein_name": "ATP synthase F(0) complex subunit g, mitochondrial", "gene_name": "ATP5MG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQFVRNLVEKTPALVNAAVTYSKPRLATFWYYAKVELVPPTPAEIPRAIQSLKKIVNSAQTGSFKQLTVKEAVLNGLVATEVLMWFYVGEIIGKRGIIGYDV", "length": 103 }, "evidence": [ { "id": "A0A4X1SSJ6", "url": "https://omabrowser.org/oma/group/A0A4X1SSJ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PDU7-1", "protein_name": "ATP synthase F(0) complex subunit g, mitochondrial", "gene_name": "Atp5mg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKFIRNLADKAPSMVAAAVTYSKPRLATFWHYARVELVPPTLGEIPTAIQSMKSIIHSAQTGNFKHLTVKEAVLNGLVATEVWMWFYIGEIIGKRGIVGYDV", "length": 103 }, "evidence": [ { "id": "A0A4X1SSJ6", "url": "https://omabrowser.org/oma/group/A0A4X1SSJ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CPQ8-1", "protein_name": "ATP synthase F(0) complex subunit g, mitochondrial", "gene_name": "Atp5mg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKFIRNFAEKAPSMVAAAVTYSKPRLATFWHYAKVELVPPTPAEIPTAIQSVKKIIQSAKTGSFKHLTVKEAVLNGLVATEVWMWFYIGEIIGKRGIVGYDV", "length": 103 }, "evidence": [ { "id": "A0A4X1SSJ6", "url": "https://omabrowser.org/oma/group/A0A4X1SSJ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SSJ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6" } ], "pmid": "" }, { "name": "proton-transporting ATP synthase complex", "id": "GO:0045259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045259", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SSJ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "proton transmembrane transporter activity", "id": "GO:0015078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015078", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SSJ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proton motive force-driven ATP synthesis", "id": "GO:0015986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015986", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SSJ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 37 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5S6G1W3-1", "uniprot_ac": "A0A5S6G1W3", "uniprot_id": "A0A5S6G1W3_PIG", "mass": { "chemical_mass": 50936.0, "monoisotopic_mass": 50936.0 }, "refseq": {}, "gene_names": [ { "name": "MTX1", "type": "recommended", "evidence": [ { "id": "A0A5S6G1W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3" } ] } ], "protein_names": [ { "name": "Metaxin-1", "type": "recommended", "evidence": [ { "id": "A0A5S6G1W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial outer membrane import complex protein 1", "type": "synonym", "evidence": [ { "id": "A0A5S6G1W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in transport of proteins into the mitochondrion. Essential for embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F7M3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7M3#function" }, { "database": "UniProtKB", "id": "ARBA00037753", "url": "https://www.uniprot.org/uniprotkb/ARBA00037753#function" }, { "database": "UniProtKB", "id": "A0A4X1W058", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W058#function" }, { "database": "UniProtKB", "id": "A0A5S6G1W3", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5S6G1W3", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MTX1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3", "locus": { "chromosome": "4", "start_pos": 94606562, "end_pos": 94611865, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006523", "url": "https://www.ensembl.org/id/ENSSSCG00000006523" } ] } } ], "crossref": [ { "id": "A0A5S6G1W3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5S6G1W3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006523", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006523", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03212", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03212", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR019564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12289:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12289:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10568", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10568", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1W058", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W058", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1W058-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W058-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5S6G1W3", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5S6G1W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F7M3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F7M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7M3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLGGPPRSPRSGPSPEGARSSPDLLQICEGTQSLPRSPKPPSGPAEPSEARGSPRPRLRDSLRRAGMKALPPFASRLWIGPLPPSPEAFGSAPRRQAAFWAGISSAFPRASPQLPTVTVVGAGGGSARRRAEAQGEVLPGQRAGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKITNPWRSPSGTLPALRTSQGEVISVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLIHTFWVDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLCGEHRPEEEEELEKELYQEARECLTLLSQRLGAQKFFFGDAPASLDAFVFSYLALLQQAKLPSGKLQAHLRGLHNLCAYCTHILSLYFPWEGAEVPRPRQTPASSETEEEPYRRRNQILSVLAGLAAMAGYALLSGIVSIQRAPPARAPSTRALGMAEEDEEE", "length": 463, "header": "tr|A0A5S6G1W3-1|A0A5S6G1W3_PIG Isoform 1 of Metaxin-1 OS=Sus scrofa OX=9823 GN=MTX1 PE=3 SV=1 CANONICAL=A0A5S6G1W3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1W058-1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3/entry#A0A4X1W058-1", "sequence": { "sequence": "MAAPMELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKITNPWRSPSGTLPALRTSQGEVISVPHKIITHLRKEVGEAHLSGAGALAQTLLFLPAFPIQIHTFWVDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLCGEHRPEEEEELEKEPQADLRLGAQKFFFGDAPASLDAFVFSYLALLQQAKLPSGKLQAHLRGLHNLCAYCTHILSLYFPWEGAEVPRPRQTPASSETEEEPYRRRNQILSVLAGLAAMAGYALLSGIVSIQRAPPARAPSTRALGMAEEDEEE", "length": 302, "header": "tr|A0A4X1W058-1|A0A4X1W058_PIG Computationally mapped isoform of Metaxin-1 OS=Sus scrofa OX=9823 GN=MTX1 PE=4 SV=1 CANONICAL=A0A5S6G1W3-1" }, "locus": { "chromosome": "4", "start_pos": 94611425, "end_pos": 94606699, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037404.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037404.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059506.3", "url": "https://www.ensembl.org/id/ENSSSCP00000059506.3" } ] } }, { "isoform_ac": "A0A5S6G1W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3/entry#A0A5S6G1W3-1", "sequence": { "sequence": "MRLGGPPRSPRSGPSPEGARSSPDLLQICEGTQSLPRSPKPPSGPAEPSEARGSPRPRLRDSLRRAGMKALPPFASRLWIGPLPPSPEAFGSAPRRQAAFWAGISSAFPRASPQLPTVTVVGAGGGSARRRAEAQGEVLPGQRAGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKITNPWRSPSGTLPALRTSQGEVISVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLIHTFWVDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLCGEHRPEEEEELEKELYQEARECLTLLSQRLGAQKFFFGDAPASLDAFVFSYLALLQQAKLPSGKLQAHLRGLHNLCAYCTHILSLYFPWEGAEVPRPRQTPASSETEEEPYRRRNQILSVLAGLAAMAGYALLSGIVSIQRAPPARAPSTRALGMAEEDEEE", "length": 463, "header": "tr|A0A5S6G1W3-1|A0A5S6G1W3_PIG Isoform 1 of Metaxin-1 OS=Sus scrofa OX=9823 GN=MTX1 PE=3 SV=1 CANONICAL=A0A5S6G1W3-1" }, "locus": { "chromosome": "4", "start_pos": 94611865, "end_pos": 94606699, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007144.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007144.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006951.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006951.3" } ] } }, { "isoform_ac": "A0A8W4F7M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3/entry#A0A8W4F7M3-1", "sequence": { "sequence": "MRLGGPPRSPRSGPSPEGARSSPDLLQICEGTQSLPRSPKPPSGPAEPSEARGSPRPRLRDSLRRAGMKALPPFASRLWIGPLPPSPEAFGSAPRRQAAFWAGISSAFPRASPQLPTVTVVGAGGGSARRRAEAQGEVLPGQRAGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKITNPWRSPSGTLPALRTSQGEVISVPHKIITHLRKEIHTFWVDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLCGEHRPEEEEELEKELYQEARECLTLLSQRLGAQKFFFGDAPASLDAFVFSYLALLQQAKLPSGKLQAHLRGLHNLCAYCTHILSLYFPWEGAEVPRPRQTPASSETEEEPYRRRNQILSVLAGLAAMAGYALLSGIVSIQRAPPARAPSTRALGMAEEDEEE", "length": 432, "header": "tr|A0A8W4F7M3-1|A0A5S6G1W3_PIG Computationally mapped isoform of Metaxin-1 OS=Sus scrofa OX=9823 GN=MTX1 PE=3 SV=1 CANONICAL=A0A5S6G1W3-1" }, "locus": { "chromosome": "4", "start_pos": 94611865, "end_pos": 94606699, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099813.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099813.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075239.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075239.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F7M3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7M3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SAM complex", "id": "GO:0001401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001401", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6G1W3", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6G1W3", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5S6G1W3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 463, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5S6G1W3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5S6G1W3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5S6G1W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3" }, { "id": "PF17171", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17171" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Metaxin glutathione S-transferase", "eco_id": "ECO_0000259", "start_pos": 320, "end_pos": 383, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5S6G1W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G1W3" }, { "id": "PF10568", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10568" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal", "eco_id": "ECO_0000259", "start_pos": 169, "end_pos": 290, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SWS9-1", "uniprot_ac": "A0A4X1SWS9", "uniprot_id": "A0A4X1SWS9_PIG", "mass": { "chemical_mass": 46683.0, "monoisotopic_mass": 46683.0 }, "refseq": { "ac": "NP_001231101", "name": "paired box protein Pax-6 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231101" }, "gene_names": [ { "name": "PAX6", "type": "recommended", "evidence": [ { "id": "A0A4X1SWS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ] }, { "name": "PAX6", "type": "synonym", "evidence": [ { "id": "NP_001231101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231101" } ] } ], "protein_names": [ { "name": "Paired box protein Pax-6", "type": "recommended", "evidence": [ { "id": "A0A4X1SWS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9/entry#names_and_taxonomy" } ] }, { "name": "Oculorhombin", "type": "synonym", "evidence": [ { "id": "A0A4X1SWS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9/entry#names_and_taxonomy" } ] }, { "name": "paired box protein Pax-6 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001231101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231101" } ] }, { "name": "paired box protein Pax-6", "type": "synonym", "evidence": [ { "id": "NP_001231101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231101" } ] } ], "function": [ { "annotation": "Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains. Acts as a transcriptional repressor of NFATC1-mediated gene expression.", "evidence": [ { "database": "UniProtKB", "id": "F2Z5M7", "url": "https://www.uniprot.org/uniprotkb/F2Z5M7#function" }, { "database": "UniProtKB", "id": "ARBA00060203", "url": "https://www.uniprot.org/uniprotkb/ARBA00060203#function" }, { "database": "UniProtKB", "id": "A0A8D0V8S9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0V8S9#function" }, { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PAX6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9", "locus": { "chromosome": "2", "start_pos": 29001200, "end_pos": 28978287, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013320", "url": "https://www.ensembl.org/id/ENSSSCG00000013320" } ] } } ], "crossref": [ { "id": "A0A4X1SWS9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SWS9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013320", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013320", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00131", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00131", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100514152", "url": "https://www.ncbi.nlm.nih.gov/gene/100514152", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514152", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514152", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSHAHST", "url": "https://omabrowser.org/oma/group/YSHAHST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SWS9", "url": "https://www.orthodb.org/?gene=A0A4X1SWS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F2Z5M7", "url": "https://www.orthodb.org/?gene=F2Z5M7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45636", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45636", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45636:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45636:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231101", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231101", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SWS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0V8S9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0V8S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0V8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0V8S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z5M7", "url": "https://www.uniprot.org/uniprotkb/F2Z5M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z5M7-1", "url": "https://www.uniprot.org/uniprotkb/F2Z5M7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ", "length": 422, "header": "tr|A0A4X1SWS9-1|A0A4X1SWS9_PIG Isoform 1 of Paired box protein Pax-6 OS=Sus scrofa OX=9823 GN=PAX6 PE=3 SV=1 CANONICAL=A0A4X1SWS9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SWS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9/entry#A0A4X1SWS9-1", "sequence": { "sequence": "MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ", "length": 422, "header": "tr|A0A4X1SWS9-1|A0A4X1SWS9_PIG Isoform 1 of Paired box protein Pax-6 OS=Sus scrofa OX=9823 GN=PAX6 PE=3 SV=1 CANONICAL=A0A4X1SWS9-1" }, "locus": { "chromosome": "2", "start_pos": 29000218, "end_pos": 28982992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054342.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054342.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040787.1", "url": "https://www.ensembl.org/id/ENSSSCP00000040787.1" } ] } }, { "isoform_ac": "A0A8D0V8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9/entry#A0A8D0V8S9-1", "sequence": { "sequence": "MHCGCLFFFLFFLLLPPLPFLHRHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ", "length": 441, "header": "tr|A0A8D0V8S9-1|A0A4X1SWS9_PIG Computationally mapped isoform of Paired box protein Pax-6 OS=Sus scrofa OX=9823 GN=PAX6 PE=3 SV=1 CANONICAL=A0A4X1SWS9-1" }, "locus": { "chromosome": "2", "start_pos": 29000218, "end_pos": 28986443, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055747.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055747.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033621.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033621.2" } ] } }, { "isoform_ac": "F2Z5M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9/entry#F2Z5M7-1", "sequence": { "sequence": "MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ", "length": 436, "header": "tr|F2Z5M7-1|F2Z5M7_PIG Computationally mapped isoform of Paired box protein Pax-6 OS=Sus scrofa OX=9823 GN=PAX6 PE=3 SV=2 CANONICAL=A0A4X1SWS9-1" }, "locus": { "chromosome": "2", "start_pos": 29000218, "end_pos": 28982992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014546.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014546.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014151.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014151.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0V8S9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0V8S9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514152", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514152", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7KAM8-1", "protein_name": "Paired box protein Pax-6", "gene_name": "Pax6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVILPWLPHSPPLPPPSQPSTLNVLSSFLTTHADAKVQVLDNENVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ", "length": 465 }, "evidence": [ { "id": "A0A4X1SWS9", "url": "https://omabrowser.org/oma/group/A0A4X1SWS9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P26367-1", "protein_name": "Paired box protein Pax-6", "gene_name": "PAX6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ", "length": 422 }, "evidence": [ { "id": "A0A4X1SWS9", "url": "https://omabrowser.org/oma/group/A0A4X1SWS9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P26630-1", "protein_name": "Paired box protein Pax-6", "gene_name": "pax6a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPQKEYYNRATWESGVASMMQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVGKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYEKLRMLNGQTGTWGTRPGWYPGTSVPGQPNQDGCQQSDGGGENTNSISSNGEDSDETQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNSSSHIPISSSFSTSVYQPIPQPTTPVSFTSGSMLGRSDTALTNTYSALPPMPSFTMANNLPMQPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQAHMNSQSMAASGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ", "length": 437 }, "evidence": [ { "id": "A0A4X1SWS9", "url": "https://omabrowser.org/oma/group/A0A4X1SWS9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P63015-1", "protein_name": "Paired box protein Pax-6", "gene_name": "Pax6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ", "length": 422 }, "evidence": [ { "id": "A0A4X1SWS9", "url": "https://omabrowser.org/oma/group/A0A4X1SWS9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P63016-1", "protein_name": "Paired box protein Pax-6", "gene_name": "Pax6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGQGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ", "length": 422 }, "evidence": [ { "id": "A0A4X1SWS9", "url": "https://omabrowser.org/oma/group/A0A4X1SWS9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1LZF1-1", "protein_name": "Paired box protein Pax-6", "gene_name": "PAX6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGATSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ", "length": 422 }, "evidence": [ { "id": "A0A4X1SWS9", "url": "https://omabrowser.org/oma/group/A0A4X1SWS9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 24, "go_terms": [ { "name": "pancreatic A cell development", "id": "GO:0003322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003322", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "nervous system process", "id": "GO:0050877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050877", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "forebrain development", "id": "GO:0030900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030900", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "blood vessel development", "id": "GO:0001568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001568", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "positive regulation of miRNA transcription", "id": "GO:1902895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902895", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "type B pancreatic cell differentiation", "id": "GO:0003309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003309", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "iris morphogenesis", "id": "GO:0061072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061072", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "cornea development in camera-type eye", "id": "GO:0061303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061303", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "ventral spinal cord development", "id": "GO:0021517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021517", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "sensory organ development", "id": "GO:0007423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007423", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 14, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "co-SMAD binding", "id": "GO:0070410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070410", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "RNA polymerase II core promoter sequence-specific DNA binding", "id": "GO:0000979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000979", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "HMG box domain binding", "id": "GO:0071837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071837", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "R-SMAD binding", "id": "GO:0070412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "transcription coregulator binding", "id": "GO:0001221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001221", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" }, { "name": "histone acetyltransferase binding", "id": "GO:0035035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035035", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SWS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 208, "end_pos": 268, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SWS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWS9" }, { "id": "PS51057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Paired", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 130, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 213, "end_pos": 215 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T5E6-1", "uniprot_ac": "A0A4X1T5E6", "uniprot_id": "A0A4X1T5E6_PIG", "mass": { "chemical_mass": 61397.0, "monoisotopic_mass": 61397.0 }, "refseq": { "ac": "XP_020921863", "name": "hepatocyte nuclear factor 1-beta isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921863" }, "gene_names": [ { "name": "HNF1B", "type": "recommended", "evidence": [ { "id": "A0A4X1T5E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ] }, { "name": "HNF1B", "type": "synonym", "evidence": [ { "id": "XP_020921863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921863" } ] }, { "name": "TCF2", "type": "synonym", "evidence": [ { "id": "XP_020921863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921863" } ] }, { "name": "vHNF-1", "type": "synonym", "evidence": [ { "id": "XP_020921863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921863" } ] } ], "protein_names": [ { "name": "Hepatocyte nuclear factor 1-beta", "type": "recommended", "evidence": [ { "id": "A0A4X1T5E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6/entry#names_and_taxonomy" } ] }, { "name": "Transcription factor 2", "type": "synonym", "evidence": [ { "id": "A0A4X1T5E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6/entry#names_and_taxonomy" } ] }, { "name": "hepatocyte nuclear factor 1-beta isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020921863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921863" } ] } ], "function": [ { "annotation": "Transcription factor that binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Binds to the FPC element in the cAMP regulatory unit of the PLAU gene. Transcriptional activity is increased by coactivator PCBD1.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4P3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4P3#function" }, { "database": "UniProtKB", "id": "ARBA00045638", "url": "https://www.uniprot.org/uniprotkb/ARBA00045638#function" }, { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6#function" }, { "database": "UniProtKB", "id": "A0A4X1T5F5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5F5#function" }, { "database": "UniProtKB", "id": "A0A5G2QWH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWH0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HNF1B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6", "locus": { "chromosome": "12", "start_pos": 39143121, "end_pos": 39201631, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000022417", "url": "https://www.ensembl.org/id/ENSSSCG00000022417" } ] } } ], "crossref": [ { "id": "A0A4X1T5E6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T5E6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000022417", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022417", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "397002", "url": "https://www.ncbi.nlm.nih.gov/gene/397002", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GQSDDTC", "url": "https://omabrowser.org/oma/group/GQSDDTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11568", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11568", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11568:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11568:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04812", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04812", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04814", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04814", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020921863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921863", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T4P3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T4P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T5E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T5F5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T5F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5F5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPSFGVKLETLPLSPGSGTEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNLTDKSSQDQLLFLFPEFSQQSQGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNTLLSHSSPHHQPSTSPPNKLPGVRYNQQGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNSSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYTHKQEPPQYSHTSRFPPAMVVTDTSSISTLTNMSSSKQCPLQAW", "length": 557, "header": "tr|A0A4X1T5E6-1|A0A4X1T5E6_PIG Isoform 1 of Hepatocyte nuclear factor 1-beta OS=Sus scrofa OX=9823 GN=HNF1B PE=3 SV=1 CANONICAL=A0A4X1T5E6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T4P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6/entry#A0A4X1T4P3-1", "sequence": { "sequence": "MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPSFGVKLETLPLSPGSGTEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFSQQSQGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNTLLSHSSPHHQPSTSPPNKLPGVRYNQQGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQMSSPSLVMPTCHLLGAQQQGPYFPHHHPPGSCCRKAQ", "length": 457, "header": "tr|A0A4X1T4P3-1|A0A4X1T4P3_PIG Computationally mapped isoform of Hepatocyte nuclear factor 1-beta OS=Sus scrofa OX=9823 GN=HNF1B PE=3 SV=1 CANONICAL=A0A4X1T5E6-1" }, "locus": { "chromosome": "12", "start_pos": 39201180, "end_pos": 39144009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090025.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090025.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072714.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072714.1" } ] } }, { "isoform_ac": "A0A4X1T5E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6/entry#A0A4X1T5E6-1", "sequence": { "sequence": "MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPSFGVKLETLPLSPGSGTEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNLTDKSSQDQLLFLFPEFSQQSQGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNTLLSHSSPHHQPSTSPPNKLPGVRYNQQGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNSSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYTHKQEPPQYSHTSRFPPAMVVTDTSSISTLTNMSSSKQCPLQAW", "length": 557, "header": "tr|A0A4X1T5E6-1|A0A4X1T5E6_PIG Isoform 1 of Hepatocyte nuclear factor 1-beta OS=Sus scrofa OX=9823 GN=HNF1B PE=3 SV=1 CANONICAL=A0A4X1T5E6-1" }, "locus": { "chromosome": "12", "start_pos": 39201180, "end_pos": 39144101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023424.2", "url": "https://www.ensembl.org/id/ENSSSCT00000023424.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028034.2", "url": "https://www.ensembl.org/id/ENSSSCP00000028034.2" } ] } }, { "isoform_ac": "A0A4X1T5F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6/entry#A0A4X1T5F5-1", "sequence": { "sequence": "MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPSFGVKLETLPLSPGSGTEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNLTDKSSQDQLLFLFPEFSQQSQGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNTLLSHSSPHHQPSTSPPNKLPGVRYNQQGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNSSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMSSPSLVMPTCHLLGAQQQGPYFPHHHPPGSCCRKAQ", "length": 548, "header": "tr|A0A4X1T5F5-1|A0A4X1T5F5_PIG Computationally mapped isoform of Hepatocyte nuclear factor 1-beta OS=Sus scrofa OX=9823 GN=HNF1B PE=3 SV=1 CANONICAL=A0A4X1T5E6-1" }, "locus": { "chromosome": "12", "start_pos": 39201180, "end_pos": 39144009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077806.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077806.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066526.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066526.1" } ] } }, { "isoform_ac": "A0A5G2QWH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6/entry#A0A5G2QWH0-1", "sequence": { "sequence": "MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPSFGVKLETLPLSPGSGTEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNLTDKSSQDQLLFLFPEFSQQSQGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNTLLSHSSPHHQPSTSPPNKLPGVRYNQQGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMQISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNSSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYTHKQEPPQYSHTSRFPPAMVVTDTSSISTLTNILLCSCLCPISSWCCRFDSWLSHLLGDLDLL", "length": 577, "header": "tr|A0A5G2QWH0-1|A0A4X1T5E6_PIG Computationally mapped isoform of Hepatocyte nuclear factor 1-beta OS=Sus scrofa OX=9823 GN=HNF1B PE=3 SV=1 CANONICAL=A0A4X1T5E6-1" }, "locus": { "chromosome": "12", "start_pos": 39201180, "end_pos": 39152500, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067450.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067450.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069206.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069206.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWH0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWH0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QNF0-1", "protein_name": "Hepatocyte nuclear factor 1-beta", "gene_name": "Hnf1b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVSKLTSLQQELLSALLSSGVTKEVLIQALEELLPTPNFGVKLETLPLSPGSGADLDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFNQQNQGPGQSEDACSEPANKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHNLNPLLTHGSPHHQPSSSPTNKLSGVRYSQQGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPGSLDPGHSLLSPDGKMQITVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVINSVASSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSINTLTSMSSSKQCPLQAW", "length": 558 }, "evidence": [ { "id": "A0A4X1T5E6", "url": "https://omabrowser.org/oma/group/A0A4X1T5E6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V1AAZ9-1", "protein_name": "HNF1 homeobox B", "gene_name": "HNF1B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVSQLSALQRELLGALLSSGATKEGLIRALEDMVPAAGFGVKLESLPLSPGGPPDGKPGFVPLANGHGKGKLSGDEGSEDGDDFDTPQILRELQALNTEEAVEQRAEVDRMISEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQGCENRTDKSSQDQLLFLFPEFNQQNQGAGQLDDACAETPSKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSGQPTHSMNLLLSHGSPHHNQPSASPPSKMPGVRYGQGASSEAASSGAISHHGSGAMVTTSQAVLQQVSPAGLDPGHGLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPSHMAQQPFMATVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSISTLTNMSSSKQCPLQAW", "length": 557 }, "evidence": [ { "id": "A0A4X1T5E6", "url": "https://omabrowser.org/oma/group/A0A4X1T5E6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MK03-1", "protein_name": "Hepatocyte nuclear factor 1-beta", "gene_name": "HNF1B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVSKLTSLQQELLSALLSSGVTKEVLIQALEELLPSPSFGVKLETLPLSPGSGAEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNLTDKSSQDQLLFLFPEFSQQSQGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSSQTHGLNTLLSHGSPHHQPSTSPPNKLPGVRYSQQASNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMQISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNSSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYTHKQEPPQYSHTSRFPSAMVVTDTSSISTLTNMSSSKQCPLQAW", "length": 558 }, "evidence": [ { "id": "A0A4X1T5E6", "url": "https://omabrowser.org/oma/group/A0A4X1T5E6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P23899-1", "protein_name": "Hepatocyte nuclear factor 1-beta", "gene_name": "Hnf1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSKLTSLQQELLSALLSSGVTKEVLIQALEELLPSPNFGVKLETLPLSPGSGADLDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQNQGPGQSEDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHNLNPLLTHGSPHHQPSSSPPNKLSGVRYSQPGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHSLLSPDSKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQGVPVINSVASSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSINTLTSMSSSKQCPLQAW", "length": 557 }, "evidence": [ { "id": "A0A4X1T5E6", "url": "https://omabrowser.org/oma/group/A0A4X1T5E6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P27889-1", "protein_name": "Hepatocyte nuclear factor 1-beta", "gene_name": "Hnf1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSKLTSLQQELLSALLSSGVTKEVLIQALEELLPSPNFGVKLETLPLSPGSGADLDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQNQGPGQSEDTCSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHNLNPLLTHGSPHHQPSSSPPNKMSGVRYNQPGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHSLLSPDSKMQITVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQGVPVINSVASSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSINTLTSMSSSKQCPLQAW", "length": 558 }, "evidence": [ { "id": "A0A4X1T5E6", "url": "https://omabrowser.org/oma/group/A0A4X1T5E6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35680-1", "protein_name": "Hepatocyte nuclear factor 1-beta", "gene_name": "HNF1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPNFGVKLETLPLSPGSGAEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQSHGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSISTLTNMSSSKQCPLQAW", "length": 557 }, "evidence": [ { "id": "A0A4X1T5E6", "url": "https://omabrowser.org/oma/group/A0A4X1T5E6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "pancreas development", "id": "GO:0031016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031016", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "insulin secretion", "id": "GO:0030073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030073", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "regulation of pronephros size", "id": "GO:0035565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035565", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "pronephric nephron tubule development", "id": "GO:0039020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5E6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T5E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" }, { "id": "PS51937", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51937" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HNF-p1", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 32, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T5E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 229, "end_pos": 310, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T5E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5E6" }, { "id": "PS51936", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51936" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POU-specific atypical", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 188, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 545, "end_pos": 547 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SNF2-1", "uniprot_ac": "A0A4X1SNF2", "uniprot_id": "A0A4X1SNF2_PIG", "mass": { "chemical_mass": 62087.0, "monoisotopic_mass": 62087.0 }, "refseq": { "ac": "XP_003480756", "name": "excitatory amino acid transporter 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480756" }, "gene_names": [ { "name": "SLC1A2", "type": "recommended", "evidence": [ { "id": "A0A4X1SNF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ] }, { "name": "SLC1A2", "type": "synonym", "evidence": [ { "id": "XP_003480756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480756" } ] } ], "protein_names": [ { "name": "Amino acid transporter", "type": "recommended", "evidence": [ { "id": "A0A4X1SNF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2/entry#names_and_taxonomy" } ] }, { "name": "excitatory amino acid transporter 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003480756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480756" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC1A2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2", "locus": { "chromosome": "2", "start_pos": 25848276, "end_pos": 25604950, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013296", "url": "https://www.ensembl.org/id/ENSSSCG00000013296" } ] } } ], "crossref": [ { "id": "A0A4X1SNF2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SNF2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013296", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013296", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100627068", "url": "https://www.ncbi.nlm.nih.gov/gene/100627068", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050746", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050746", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100627068", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627068", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AK79", "url": "https://www.orthodb.org/?gene=A0A287AK79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SNF2", "url": "https://www.orthodb.org/?gene=A0A4X1SNF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11958:SF93", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11958:SF93", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00375", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-210455", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-210455", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-210500", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-210500", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9958863", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9958863", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003480756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480756", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "70699", "url": "https://www.rhea-db.org/rhea/70699", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70851", "url": "https://www.rhea-db.org/rhea/70851", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71379", "url": "https://www.rhea-db.org/rhea/71379", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AK79", "url": "https://www.uniprot.org/uniprotkb/A0A287AK79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AK79-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AK79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AME2", "url": "https://www.uniprot.org/uniprotkb/A0A287AME2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AME2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AME2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AT59", "url": "https://www.uniprot.org/uniprotkb/A0A287AT59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AT59-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AT59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B6T1", "url": "https://www.uniprot.org/uniprotkb/A0A287B6T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B6T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B6T1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SNF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0KJY4", "url": "https://www.uniprot.org/uniprotkb/A0A8D0KJY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0KJY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0KJY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SHF9", "url": "https://www.uniprot.org/uniprotkb/F1SHF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SHF9-1", "url": "https://www.uniprot.org/uniprotkb/F1SHF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASTEGANNMPKQVEVRMHDSHLSSEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGFLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVISLLNETVTEGPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELETIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEAWKREK", "length": 574, "header": "tr|A0A4X1SNF2-1|A0A4X1SNF2_PIG Isoform 1 of Amino acid transporter OS=Sus scrofa OX=9823 GN=SLC1A2 PE=3 SV=1 CANONICAL=A0A4X1SNF2-1" }, "isoforms": [ { "isoform_ac": "A0A287AK79-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2/entry#A0A287AK79-1", "sequence": { "sequence": "MERPEDHMRSANNMPKQVEVRMHDSHLSSEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGFLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVISLLNETVTEGPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELETIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEAWKREK", "length": 578, "header": "tr|A0A287AK79-1|A0A4X1SNF2_PIG Computationally mapped isoform of Amino acid transporter OS=Sus scrofa OX=9823 GN=SLC1A2 PE=3 SV=1 CANONICAL=A0A4X1SNF2-1" }, "locus": { "chromosome": "2", "start_pos": 25762463, "end_pos": 25641672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098717.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098717.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077167.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077167.1" } ] } }, { "isoform_ac": "A0A287AME2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2/entry#A0A287AME2-1", "sequence": { "sequence": "MASTEGANNMPKQVEVRMHDSHLSSEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGFLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVISLLNETVTEGPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELETIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVPFPFMDIETLDSYRIYFSKESRNSSLCESQIIQLCV", "length": 588, "header": "tr|A0A287AME2-1|A0A4X1SNF2_PIG Computationally mapped isoform of Amino acid transporter OS=Sus scrofa OX=9823 GN=SLC1A2 PE=3 SV=2 CANONICAL=A0A4X1SNF2-1" }, "locus": { "chromosome": "2", "start_pos": 25757824, "end_pos": 25605563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048330.2", "url": "https://www.ensembl.org/id/ENSSSCT00000048330.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045085.2", "url": "https://www.ensembl.org/id/ENSSSCP00000045085.2" } ] } }, { "isoform_ac": "A0A287AT59-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2/entry#A0A287AT59-1", "sequence": { "sequence": "MPKQVEVRMHDSHLSSEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGFLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVISLLNETVTEGPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELETIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVPFPFMDIETCI", "length": 554, "header": "tr|A0A287AT59-1|A0A4X1SNF2_PIG Computationally mapped isoform of Amino acid transporter OS=Sus scrofa OX=9823 GN=SLC1A2 PE=3 SV=1 CANONICAL=A0A4X1SNF2-1" }, "locus": { "chromosome": "2", "start_pos": 25757698, "end_pos": 25707099, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051921.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051921.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047267.1", "url": "https://www.ensembl.org/id/ENSSSCP00000047267.1" } ] } }, { "isoform_ac": "A0A287B6T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2/entry#A0A287B6T1-1", "sequence": { "sequence": "LLRPEPLQLANNMPKQVEVRMHDSHLSSEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGFLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVISLLNETVTEGPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELETIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVPFPFMDIETCI", "length": 566, "header": "tr|A0A287B6T1-1|A0A4X1SNF2_PIG Computationally mapped isoform of Amino acid transporter OS=Sus scrofa OX=9823 GN=SLC1A2 PE=3 SV=3 CANONICAL=A0A4X1SNF2-1" }, "locus": { "chromosome": "2", "start_pos": 25757698, "end_pos": 25707010, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053521.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053521.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052232.3", "url": "https://www.ensembl.org/id/ENSSSCP00000052232.3" } ] } }, { "isoform_ac": "A0A4X1SNF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2/entry#A0A4X1SNF2-1", "sequence": { "sequence": "MASTEGANNMPKQVEVRMHDSHLSSEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGFLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVISLLNETVTEGPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELETIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEAWKREK", "length": 574, "header": "tr|A0A4X1SNF2-1|A0A4X1SNF2_PIG Isoform 1 of Amino acid transporter OS=Sus scrofa OX=9823 GN=SLC1A2 PE=3 SV=1 CANONICAL=A0A4X1SNF2-1" }, "locus": { "chromosome": "2", "start_pos": 25762463, "end_pos": 25605563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051003.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051003.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049854.3", "url": "https://www.ensembl.org/id/ENSSSCP00000049854.3" } ] } }, { "isoform_ac": "A0A8D0KJY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2/entry#A0A8D0KJY4-1", "sequence": { "sequence": "MASTEGANNMPKQVEVRMHDSHLSSEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGFLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVISLLNETVTEGPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMCAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELETIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEAWKREK", "length": 496, "header": "tr|A0A8D0KJY4-1|A0A4X1SNF2_PIG Computationally mapped isoform of Amino acid transporter OS=Sus scrofa OX=9823 GN=SLC1A2 PE=3 SV=1 CANONICAL=A0A4X1SNF2-1" }, "locus": { "chromosome": "2", "start_pos": 25762463, "end_pos": 25605563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092276.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092276.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077122.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077122.1" } ] } }, { "isoform_ac": "F1SHF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2/entry#F1SHF9-1", "sequence": { "sequence": "SANNMPKQVEVRMHDSHLSSEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGFLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVISLLNETVTEGPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSEVSTLKTGTFLLLKMLSKPILYEWRLHKSLLQRQSAATLPKAGRPKATPTQSLSTWNQPDALKQYVSYWEVLDARMYTPVLFAAQMALGWIRGITTCPSMNPYLQKKIQRLSTCKAVARDFIIPMNDTSCSARLPSREGC", "length": 634, "header": "tr|F1SHF9-1|A0A4X1SNF2_PIG Computationally mapped isoform of Amino acid transporter OS=Sus scrofa OX=9823 GN=SLC1A2 PE=3 SV=5 CANONICAL=A0A4X1SNF2-1" }, "locus": { "chromosome": "2", "start_pos": 25844387, "end_pos": 25707087, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014522.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014522.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014129.5", "url": "https://www.ensembl.org/id/ENSSSCP00000014129.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SHF9", "url": "https://www.uniprot.org/uniprotkb/F1SHF9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100627068", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627068", "resource": "KEGG Pathway" }, { "id": "R-SSC-210455", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-210455", "resource": "Reactome", "description": "Astrocytic Glutamate-Glutamine Uptake And Metabolism" }, { "id": "R-SSC-210500", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-210500", "resource": "Reactome", "description": "Glutamate Neurotransmitter Release Cycle" }, { "id": "R-SSC-9958863", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9958863", "resource": "Reactome", "description": "SLC-mediated transport of amino acids" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "astrocyte projection", "id": "GO:0097449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097449", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "axolemma", "id": "GO:0030673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030673", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "neuron projection terminus", "id": "GO:0044306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044306", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "membrane protein complex", "id": "GO:0098796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098796", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "glutathione biosynthetic process", "id": "GO:0006750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006750", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "protein homotrimerization", "id": "GO:0070207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070207", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "transepithelial transport", "id": "GO:0070633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070633", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "D-aspartate import across plasma membrane", "id": "GO:0070779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070779", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "L-glutamate import across plasma membrane", "id": "GO:0098712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098712", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "L-aspartate import across plasma membrane", "id": "GO:0140009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140009", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "cellular response to cocaine", "id": "GO:0071314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071314", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "neurotransmitter reuptake", "id": "GO:0098810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098810", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "transport across blood-brain barrier", "id": "GO:0150104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150104", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transport", "id": "GO:0015813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015813", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "L-aspartate transmembrane transport", "id": "GO:0070778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070778", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "L-alpha-amino acid transmembrane transport", "id": "GO:1902475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902475", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "monoatomic anion transmembrane transporter activity", "id": "GO:0008509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008509", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "high-affinity L-glutamate transmembrane transporter activity", "id": "GO:0005314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005314", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "cysteine transmembrane transporter activity", "id": "GO:0033229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033229", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "neutral L-amino acid transmembrane transporter activity", "id": "GO:0015175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015175", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "glutamate:sodium symporter activity", "id": "GO:0015501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015501", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transporter activity", "id": "GO:0005313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005313", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNF2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "70699", "name": "", "equation": "K(+)(in) + L-glutamate(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-glutamate(in) + 3 Na(+)(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70699", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70699" } ] }, { "id": "70851", "name": "", "equation": "K(+)(in) + L-aspartate(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-aspartate(in) + 3 Na(+)(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70851", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70851" } ] }, { "id": "71379", "name": "", "equation": "D-aspartate(out) + K(+)(in) + 3 Na(+)(out) + H(+)(out) = D-aspartate(in) + K(+)(out) + 3 Na(+)(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71379", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71379" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 216, "end_pos": 218 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1VJP7-1", "uniprot_ac": "A0A5K1VJP7", "uniprot_id": "A0A5K1VJP7_PIG", "mass": { "chemical_mass": 10772.0, "monoisotopic_mass": 10772.0 }, "refseq": {}, "gene_names": [ { "name": "PRDX1", "type": "recommended", "evidence": [ { "id": "A0A5K1VJP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ] } ], "protein_names": [ { "name": "thioredoxin-dependent peroxiredoxin", "type": "recommended", "evidence": [ { "id": "A0A5K1VJP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7/entry#names_and_taxonomy" } ] }, { "name": "1.11.1.24", "type": "synonym", "evidence": [ { "id": "A0A5K1VJP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZND5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZND5#function" }, { "database": "UniProtKB", "id": "ARBA00045796", "url": "https://www.uniprot.org/uniprotkb/ARBA00045796#function" }, { "database": "UniProtKB", "id": "F1S3U9", "url": "https://www.uniprot.org/uniprotkb/F1S3U9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PRDX1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7", "locus": { "chromosome": "6", "start_pos": 165861442, "end_pos": 165824395, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003914", "url": "https://www.ensembl.org/id/ENSSSCG00000003914" } ] } } ], "crossref": [ { "id": "A0A5K1VJP7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1VJP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003914", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003914", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03015", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03015", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512476", "url": "https://www.ncbi.nlm.nih.gov/gene/100512476", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512476", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512476", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FWYPKDF", "url": "https://omabrowser.org/oma/group/FWYPKDF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3U9", "url": "https://www.orthodb.org/?gene=F1S3U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10681", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10681", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10681:SF111", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10681:SF111", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10681:SF163", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10681:SF163", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00578", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00578", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3000471", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3000471", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3299685", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3299685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9818027", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9818027", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "62620", "url": "https://www.rhea-db.org/rhea/62620", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZND5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZND5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZND5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZND5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VJP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FHP4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FHP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3U9", "url": "https://www.uniprot.org/uniprotkb/F1S3U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3U9-1", "url": "https://www.uniprot.org/uniprotkb/F1S3U9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSGNAKIGHRAPHFKATADEGISFRGLFIIDDKGILRQITINDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK", "length": 97, "header": "tr|A0A5K1VJP7-1|A0A5K1VJP7_PIG Isoform 1 of thioredoxin-dependent peroxiredoxin OS=Sus scrofa OX=9823 GN=PRDX1 PE=1 SV=1 CANONICAL=A0A5K1VJP7-1" }, "isoforms": [ { "isoform_ac": "A0A286ZND5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7/entry#A0A286ZND5-1", "sequence": { "sequence": "MGQQRRNSPRLEQRVTSPGFSADSNMSSGNAKIGHRAPHFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSERAEEFKKLNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLISDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITINDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK", "length": 224, "header": "tr|A0A286ZND5-1|A0A5K1VJP7_PIG Computationally mapped isoform of thioredoxin-dependent peroxiredoxin OS=Sus scrofa OX=9823 GN=PRDX1 PE=1 SV=1 CANONICAL=A0A5K1VJP7-1" }, "locus": { "chromosome": "6", "start_pos": 165859648, "end_pos": 165824594, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050402.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050402.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032967.1", "url": "https://www.ensembl.org/id/ENSSSCP00000032967.1" } ] } }, { "isoform_ac": "A0A5K1VJP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7/entry#A0A5K1VJP7-1", "sequence": { "sequence": "MSSGNAKIGHRAPHFKATADEGISFRGLFIIDDKGILRQITINDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK", "length": 97, "header": "tr|A0A5K1VJP7-1|A0A5K1VJP7_PIG Isoform 1 of thioredoxin-dependent peroxiredoxin OS=Sus scrofa OX=9823 GN=PRDX1 PE=1 SV=1 CANONICAL=A0A5K1VJP7-1" }, "locus": { "chromosome": "6", "start_pos": 165859648, "end_pos": 165849601, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027628.3", "url": "https://www.ensembl.org/id/ENSSSCT00000027628.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023880.3", "url": "https://www.ensembl.org/id/ENSSSCP00000023880.3" } ] } }, { "isoform_ac": "A0A8W4FHP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7/entry#A0A8W4FHP4-1", "sequence": { "sequence": "MSSGNAKIGHRAPHFKATAVMGLFIIDDKGILRQITINDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK", "length": 92, "header": "tr|A0A8W4FHP4-1|A0A5K1VJP7_PIG Computationally mapped isoform of thioredoxin-dependent peroxiredoxin OS=Sus scrofa OX=9823 GN=PRDX1 PE=1 SV=1 CANONICAL=A0A5K1VJP7-1" }, "locus": { "chromosome": "6", "start_pos": 165859648, "end_pos": 165849601, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106659.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106659.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078840.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078840.1" } ] } }, { "isoform_ac": "F1S3U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7/entry#F1S3U9-1", "sequence": { "sequence": "MSSGNAKIGHRAPHFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSERAEEFKKLNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLISDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITINDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK", "length": 199, "header": "tr|F1S3U9-1|A0A5K1VJP7_PIG Computationally mapped isoform of thioredoxin-dependent peroxiredoxin OS=Sus scrofa OX=9823 GN=PRDX1 PE=1 SV=3 CANONICAL=A0A5K1VJP7-1" }, "locus": { "chromosome": "6", "start_pos": 165859648, "end_pos": 165849601, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004329.6", "url": "https://www.ensembl.org/id/ENSSSCT00000004329.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004229.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004229.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZND5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZND5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512476", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512476", "resource": "KEGG Pathway" }, { "id": "R-SSC-3000471", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3000471", "resource": "Reactome", "description": "Scavenging by Class B Receptors" }, { "id": "R-SSC-3299685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3299685", "resource": "Reactome", "description": "Detoxification of Reactive Oxygen Species" }, { "id": "R-SSC-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-SSC-9818027", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9818027", "resource": "Reactome", "description": "NFE2L2 regulating anti-oxidant/detoxification enzymes" } ], "orthologs": [ { "uniprot_canonical_ac": "P0CB50-1", "protein_name": "Peroxiredoxin-1", "gene_name": "PRDX1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSGKAFIGKPAPDFTATAVMPDGQFKDIKLSDYRGKYVVFFFYPLDFTFVCPTEIIAYSDRADEFKKINCEIIGASVDSHFCHLAWINTPKKQGGLGTMKIPLVSDTKRVIAKDYGVLKEDEGIAYRGLFIIDEKGILRQITINDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK", "length": 199 }, "evidence": [ { "id": "A0A5K1VJP7", "url": "https://omabrowser.org/oma/group/A0A5K1VJP7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P34760-1", "protein_name": "Peroxiredoxin TSA1", "gene_name": "TSA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVAQVQKQAPTFKKTAVVDGVFDEVSLDKYKGKYVVLAFIPLAFTFVCPTEIIAFSEAAKKFEEQGAQVLFASTDSEYSLLAWTNIPRKEGGLGPINIPLLADTNHSLSRDYGVLIEEEGVALRGLFIIDPKGVIRHITINDLPVGRNVDEALRLVEAFQWTDKNGTVLPCNWTPGAATIKPTVEDSKEYFEAANK", "length": 196 }, "evidence": [ { "id": "A0A5K1VJP7", "url": "https://omabrowser.org/oma/group/A0A5K1VJP7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P35700-1", "protein_name": "Peroxiredoxin-1", "gene_name": "Prdx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSGNAKIGYPAPNFKATAVMPDGQFKDISLSEYKGKYVVFFFYPLDFTFVCPTEIIAFSDRADEFKKLNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLISDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITINDLPVGRSVDEIIRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVNKSKEYFSKQK", "length": 199 }, "evidence": [ { "id": "A0A5K1VJP7", "url": "https://omabrowser.org/oma/group/A0A5K1VJP7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q06830-1", "protein_name": "Peroxiredoxin-1", "gene_name": "PRDX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK", "length": 199 }, "evidence": [ { "id": "A0A5K1VJP7", "url": "https://omabrowser.org/oma/group/A0A5K1VJP7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q555L5-1", "protein_name": "Peroxiredoxin-4", "gene_name": "prdx4", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSATKLFKNLSKSVVQLKTVKPVSSLNFGYIKTRQFSTSTTDSSNLFLNNNNQFQNFTFPTKQQIRIRKPAPAFKGQAVVNGEFKEISLDDYKGKYLYLFFYPLDFTFVCPTEIIAFSNAAEEFKKAGCELVGCSIDSPFTHLAWINTPRKEGGLGGINIPLLSDLTHQISKDYGVYIEEDGHTIRGSILIDKEGLVRVITMNDNPVGRSVDEAIRTLKALKFTDQFGEVCPANWSEGDKSMKADPKGSKEYFEAVNK", "length": 259 }, "evidence": [ { "id": "A0A5K1VJP7", "url": "https://omabrowser.org/oma/group/A0A5K1VJP7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5E947-1", "protein_name": "Peroxiredoxin-1", "gene_name": "PRDX1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSGNAKIGHRAPQFKATAVMPDGQFKDISLADYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLISDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITINDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK", "length": 199 }, "evidence": [ { "id": "A0A5K1VJP7", "url": "https://omabrowser.org/oma/group/A0A5K1VJP7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q63716-1", "protein_name": "Peroxiredoxin-1", "gene_name": "Prdx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGNAKIGHPAPSFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITINDLPVGRSVDEILRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVNKSKEYFSKQK", "length": 199 }, "evidence": [ { "id": "A0A5K1VJP7", "url": "https://omabrowser.org/oma/group/A0A5K1VJP7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "pmid": "" }, { "name": "thioredoxin peroxidase activity", "id": "GO:0008379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008379", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "pmid": "" }, { "name": "thioredoxin-dependent peroxiredoxin activity", "id": "GO:0140824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140824", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "natural killer cell activation", "id": "GO:0030101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030101", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "pmid": "" }, { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "pmid": "" }, { "name": "removal of superoxide radicals", "id": "GO:0019430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019430", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "pmid": "" }, { "name": "hydrogen peroxide catabolic process", "id": "GO:0042744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042744", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "pmid": "" }, { "name": "leukocyte activation", "id": "GO:0045321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045321", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VJP7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "62620", "name": "", "equation": "a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "62620", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62620" } ] }, { "id": "R-SSC-3341343", "name": "PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-3341343", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3341343" } ] }, { "id": "R-SSC-5631885", "name": "PRDX1 overoxidizes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29408" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5631885", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5631885" } ] }, { "id": "R-SSC-5631903", "name": "SESN1,2,3 bind overoxidized PRDX1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5631903", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5631903" } ] }, { "id": "R-SSC-9760094", "name": "SRXN1 reduces hyperoxidized PRDX1 dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9760094", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9760094" } ] }, { "id": "R-SSC-9968214", "name": "CD5L (AIM) binds damage-associated patterns (DAMPs)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9968214", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9968214" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29408", "participant_name": "H2O2 [cytosol]", "crossref": [ { "id": "16240", "database": "ChEBI", "url": "" }, { "id": "C00027", "database": "COMPOUND", "url": "" }, { "id": "11533079", "database": "PubChem Substance", "url": "" }, { "id": "HMDB0003125", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1VJP7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 97, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1VJP7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1VJP7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1VJP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VJP7" }, { "id": "PF10417", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10417" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peroxiredoxin C-terminal", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 95, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RKH3-1", "uniprot_ac": "A0A5G2RKH3", "uniprot_id": "A0A5G2RKH3_PIG", "mass": { "chemical_mass": 84805.0, "monoisotopic_mass": 84805.0 }, "refseq": {}, "gene_names": [ { "name": "DLG4", "type": "recommended", "evidence": [ { "id": "A0A5G2RKH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ] } ], "protein_names": [ { "name": "Discs large MAGUK scaffold protein 4", "type": "synonym", "evidence": [ { "id": "A0A5G2RKH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DLG4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3", "locus": { "chromosome": "12", "start_pos": 52550141, "end_pos": 52575143, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000024285", "url": "https://www.ensembl.org/id/ENSSSCG00000024285" } ] } } ], "crossref": [ { "id": "A0A5G2RKH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RKH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000024285", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000024285", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06723", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06723", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06724", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06724", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06795", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06795", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12030", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12030", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626077", "url": "https://www.ncbi.nlm.nih.gov/gene/100626077", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "I3LMS7", "url": "https://www.orthodb.org/?gene=I3LMS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-399719", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-399719", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-438066", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-438066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-451308", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-451308", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5625900", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5625900", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5682910", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5682910", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6794361", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6794361", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8849932", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8849932", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZUM2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZUM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B083", "url": "https://www.uniprot.org/uniprotkb/A0A287B083", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B083-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B083-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5C8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5C8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8N4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RIW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RIW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQA7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LMS7", "url": "https://www.uniprot.org/uniprotkb/I3LMS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LMS7-1", "url": "https://www.uniprot.org/uniprotkb/I3LMS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LRJ0", "url": "https://www.uniprot.org/uniprotkb/I3LRJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LRJ0-1", "url": "https://www.uniprot.org/uniprotkb/I3LRJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEGPRAPRSALWLLAPPLLRWAPPLLTVLHSDLFQALLDILDYYEASISESQKYRYQDEDTPPLEHSPAHLPNQVNAPELVHVAERNLSHLEAVQGVVGHAHFSPLKGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKLMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSSAYLSDSYAPPDITSSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRSPGWAARMEAMGPLTSWGSTPCLPLGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRASKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "length": 766, "header": "tr|A0A5G2RKH3-1|A0A5G2RKH3_PIG Isoform 1 of Discs large MAGUK scaffold protein 4 OS=Sus scrofa OX=9823 GN=DLG4 PE=1 SV=2 CANONICAL=A0A5G2RKH3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZUM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3/entry#A0A286ZUM2-1", "sequence": { "sequence": "MGWRTGRGRSWSGPGAWRTKYRYQDEDTPPLEHSPAHLPNQVNAPELVHVAERNLSHLEAVQGVVGHAHFSPLKANSPPVIVNTDTLEAPGYLQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKLMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSSAYLSDSYAPPDITSSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRSPGWAARMEAMGPLTSWGSTPCLPLGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRASKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "length": 769, "header": "tr|A0A286ZUM2-1|A0A5G2RKH3_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 4 OS=Sus scrofa OX=9823 GN=DLG4 PE=1 SV=2 CANONICAL=A0A5G2RKH3-1" }, "locus": { "chromosome": "12", "start_pos": 52565913, "end_pos": 52550972, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063962.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063962.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035160.3", "url": "https://www.ensembl.org/id/ENSSSCP00000035160.3" } ] } }, { "isoform_ac": "A0A287B083-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3/entry#A0A287B083-1", "sequence": { "sequence": "ILLNWKGGAWKYRYQDEDTPPLEHSPAHLPNQVNAPELVHVAERNLSHLEAVQGVVGHAHFSPLKANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKLMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSSAYLSDSYAPPDITSSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRASKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "length": 757, "header": "tr|A0A287B083-1|A0A5G2RKH3_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 4 OS=Sus scrofa OX=9823 GN=DLG4 PE=1 SV=2 CANONICAL=A0A5G2RKH3-1" }, "locus": { "chromosome": "12", "start_pos": 52570235, "end_pos": 52550972, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057407.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057407.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049514.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049514.2" } ] } }, { "isoform_ac": "A0A5G2R5C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3/entry#A0A5G2R5C8-1", "sequence": { "sequence": "MQGTWAGQSWVQHVCTCVYVTWKGSCAGGPLAYRVSFFSSQANSPPVIVNTDTLEAPGYLQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKLMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSSAYLSDSYAPPDITSSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRSPGWAARMEAMGPLTSWGSTPCLPLGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEGCRDSQASFCLPALV", "length": 648, "header": "tr|A0A5G2R5C8-1|A0A5G2RKH3_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 4 OS=Sus scrofa OX=9823 GN=DLG4 PE=1 SV=1 CANONICAL=A0A5G2RKH3-1" }, "locus": { "chromosome": "12", "start_pos": 52562383, "end_pos": 52551978, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068331.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068331.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071524.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071524.1" } ] } }, { "isoform_ac": "A0A5G2R8N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3/entry#A0A5G2R8N4-1", "sequence": { "sequence": "MQGTWAGQSWVQHVCTCVYVTWKGSCAGGPLAYRVSFFSSQANSPPVIVNTDTLEAPGYVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKLMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSSAYLSDSYAPPDITSSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRSPGWAARMEAMGPLTSWGSTPCLPLGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRASKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "length": 734, "header": "tr|A0A5G2R8N4-1|A0A5G2RKH3_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 4 OS=Sus scrofa OX=9823 GN=DLG4 PE=1 SV=2 CANONICAL=A0A5G2RKH3-1" }, "locus": { "chromosome": "12", "start_pos": 52562383, "end_pos": 52550972, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075042.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075042.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073446.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073446.2" } ] } }, { "isoform_ac": "A0A5G2RIW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3/entry#A0A5G2RIW1-1", "sequence": { "sequence": "MEGRGGVCQANSPPVIVNTDTLEAPGYVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKLMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSSAYLSDSYAPPDITSSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRASKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "length": 698, "header": "tr|A0A5G2RIW1-1|A0A5G2RKH3_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 4 OS=Sus scrofa OX=9823 GN=DLG4 PE=1 SV=2 CANONICAL=A0A5G2RKH3-1" }, "locus": { "chromosome": "12", "start_pos": 52564583, "end_pos": 52550972, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066654.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066654.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071614.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071614.1" } ] } }, { "isoform_ac": "A0A5G2RKH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3/entry#A0A5G2RKH3-1", "sequence": { "sequence": "MSEGPRAPRSALWLLAPPLLRWAPPLLTVLHSDLFQALLDILDYYEASISESQKYRYQDEDTPPLEHSPAHLPNQVNAPELVHVAERNLSHLEAVQGVVGHAHFSPLKGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKLMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSSAYLSDSYAPPDITSSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRSPGWAARMEAMGPLTSWGSTPCLPLGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRASKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "length": 766, "header": "tr|A0A5G2RKH3-1|A0A5G2RKH3_PIG Isoform 1 of Discs large MAGUK scaffold protein 4 OS=Sus scrofa OX=9823 GN=DLG4 PE=1 SV=2 CANONICAL=A0A5G2RKH3-1" }, "locus": { "chromosome": "12", "start_pos": 52575143, "end_pos": 52550972, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087897.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087897.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072612.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072612.2" } ] } }, { "isoform_ac": "A0A8W4FMJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3/entry#A0A8W4FMJ3-1", "sequence": { "sequence": "MVGGRGRGWGPHLGDPRIPGAQGLGQICAGGPLAYRVSFFSSQANSPPVIVNTDTLEAPGYLQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKLMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSSAYLSDSYAPPDITSSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRSPGWAARMEAMGPLTSWGSTPCLPLGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRASKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "length": 738, "header": "tr|A0A8W4FMJ3-1|A0A5G2RKH3_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 4 OS=Sus scrofa OX=9823 GN=DLG4 PE=1 SV=1 CANONICAL=A0A5G2RKH3-1" }, "locus": { "chromosome": "12", "start_pos": 52562752, "end_pos": 52550972, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105864.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105864.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080407.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080407.1" } ] } }, { "isoform_ac": "A0A8W4FQA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3/entry#A0A8W4FQA7-1", "sequence": { "sequence": "MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKLMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSSAYLSDSYAPPDITSSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQVGAGGPSSSSSLSLPCGLPPAVSNSLSLSVCLFPCWVSAPLLHLLLLLGNSVACLLSRAPPPPPSLGS", "length": 690, "header": "tr|A0A8W4FQA7-1|A0A5G2RKH3_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 4 OS=Sus scrofa OX=9823 GN=DLG4 PE=1 SV=1 CANONICAL=A0A5G2RKH3-1" }, "locus": { "chromosome": "12", "start_pos": 52573555, "end_pos": 52553006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094944.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094944.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081179.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081179.1" } ] } }, { "isoform_ac": "I3LMS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3/entry#I3LMS7-1", "sequence": { "sequence": "MSARNRFASMCLCVKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKLMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSSAYLSDSYAPPDITSSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRASKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "length": 728, "header": "tr|I3LMS7-1|A0A5G2RKH3_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 4 OS=Sus scrofa OX=9823 GN=DLG4 PE=1 SV=2 CANONICAL=A0A5G2RKH3-1" }, "locus": { "chromosome": "12", "start_pos": 52568835, "end_pos": 52550972, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031364.4", "url": "https://www.ensembl.org/id/ENSSSCT00000031364.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025399.2", "url": "https://www.ensembl.org/id/ENSSSCP00000025399.2" } ] } }, { "isoform_ac": "I3LRJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3/entry#I3LRJ0-1", "sequence": { "sequence": "KYRYQDEDTPPLEHSPAHLPNQVNAPELVHVAERNLSHLEAVQGVVGHAHFSPLKANSPPVIVNTDTLEAPGYLQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKLMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSSAYLSDSYAPPDITSSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRASKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "length": 746, "header": "tr|I3LRJ0-1|A0A5G2RKH3_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 4 OS=Sus scrofa OX=9823 GN=DLG4 PE=1 SV=3 CANONICAL=A0A5G2RKH3-1" }, "locus": { "chromosome": "12", "start_pos": 52565759, "end_pos": 52550972, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022437.3", "url": "https://www.ensembl.org/id/ENSSSCT00000022437.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026725.3", "url": "https://www.ensembl.org/id/ENSSSCP00000026725.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LMS7", "url": "https://www.uniprot.org/uniprotkb/I3LMS7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-399719", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-399719", "resource": "Reactome", "description": "Trafficking of AMPA receptors" }, { "id": "R-SSC-438066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-438066", "resource": "Reactome", "description": "Unblocking of NMDA receptors, glutamate binding and activation" }, { "id": "R-SSC-451308", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-451308", "resource": "Reactome", "description": "Activation of Ca-permeable Kainate Receptor" }, { "id": "R-SSC-5625900", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5625900", "resource": "Reactome", "description": "RHO GTPases activate CIT" }, { "id": "R-SSC-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-SSC-5682910", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5682910", "resource": "Reactome", "description": "LGI-ADAM interactions" }, { "id": "R-SSC-6794361", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6794361", "resource": "Reactome", "description": "Neurexins and neuroligins" }, { "id": "R-SSC-8849932", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8849932", "resource": "Reactome", "description": "Synaptic adhesion-like molecules" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 17, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "AMPA glutamate receptor complex", "id": "GO:0032281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032281", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "cortical cytoskeleton", "id": "GO:0030863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030863", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "cerebellar mossy fiber", "id": "GO:0044300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044300", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "neuron projection terminus", "id": "GO:0044306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044306", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "excitatory synapse", "id": "GO:0060076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060076", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "juxtaparanode region of axon", "id": "GO:0044224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044224", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "synaptic membrane", "id": "GO:0097060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097060", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 18, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "neuromuscular process controlling balance", "id": "GO:0050885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050885", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "establishment of protein localization", "id": "GO:0045184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045184", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "social behavior", "id": "GO:0035176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035176", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "dendritic spine morphogenesis", "id": "GO:0060997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060997", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "locomotory exploration behavior", "id": "GO:0035641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035641", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "AMPA glutamate receptor clustering", "id": "GO:0097113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097113", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "protein localization to synapse", "id": "GO:0035418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035418", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "receptor localization to synapse", "id": "GO:0097120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097120", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "cellular response to potassium ion", "id": "GO:0035865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035865", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "vocalization behavior", "id": "GO:0071625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071625", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "positive regulation of synaptic transmission", "id": "GO:0050806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050806", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "regulation of grooming behavior", "id": "GO:2000821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000821", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "regulation of postsynaptic membrane neurotransmitter receptor levels", "id": "GO:0099072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099072", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0099645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099645", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "ionotropic glutamate receptor binding", "id": "GO:0035255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035255", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RKH3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 766, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RKH3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RKH3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RKH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" }, { "id": "PS50052", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50052" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate kinase-like", "eco_id": "ECO_0000259", "start_pos": 576, "end_pos": 751, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RKH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 108, "end_pos": 190, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RKH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKH3" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 466, "end_pos": 536, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TAL1-1", "uniprot_ac": "A0A4X1TAL1", "uniprot_id": "A0A4X1TAL1_PIG", "mass": { "chemical_mass": 91844.0, "monoisotopic_mass": 91844.0 }, "refseq": { "ac": "XP_005656995", "name": "cell division cycle protein 27 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656995" }, "gene_names": [ { "name": "CDC27", "type": "recommended", "evidence": [ { "id": "A0A4X1TAL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ] }, { "name": "CDC27", "type": "synonym", "evidence": [ { "id": "XP_005656995", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656995" } ] } ], "protein_names": [ { "name": "Cell division cycle protein 27 homolog", "type": "recommended", "evidence": [ { "id": "A0A4X1TAL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1/entry#names_and_taxonomy" } ] }, { "name": "cell division cycle protein 27 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005656995", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656995" } ] } ], "function": [ { "annotation": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1#function" }, { "database": "UniProtKB", "id": "ARBA00045696", "url": "https://www.uniprot.org/uniprotkb/ARBA00045696#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CDC27", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1", "locus": { "chromosome": "12", "start_pos": 16882269, "end_pos": 16810910, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017308", "url": "https://www.ensembl.org/id/ENSSSCG00000017308" } ] } } ], "crossref": [ { "id": "A0A4X1TAL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TAL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017308", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017308", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100517185", "url": "https://www.ncbi.nlm.nih.gov/gene/100517185", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TAL1", "url": "https://www.orthodb.org/?gene=A0A4X1TAL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12558", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12558", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12558:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12558:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174048", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174048", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174084", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174084", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174154", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174154", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174178", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174184", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174184", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-176407", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-176408", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-176409", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-176412", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176412", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-179409", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-179409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2559582", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559582", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68867", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68867", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-69017", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69017", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005656995", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656995", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B1H7", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1H7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BI65", "url": "https://www.uniprot.org/uniprotkb/A0A287BI65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BI65-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BI65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T789", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T789", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T789-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T789-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TAL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRLLKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSYDDIVTEFGDSACFTLSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKLTSLQNFSNCLPNSCTTLVSNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVISPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPTALSPLTPSFGILPLETPSPGDGSYLQNYTNTSSVIDVPSTGAPSKKSVTRIGQTGTKSVFSQSGNSREVTPILVAQTQSSGPQTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAGLMSLLREMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF", "length": 824, "header": "tr|A0A4X1TAL1-1|A0A4X1TAL1_PIG Isoform 1 of Cell division cycle protein 27 homolog OS=Sus scrofa OX=9823 GN=CDC27 PE=3 SV=1 CANONICAL=A0A4X1TAL1-1" }, "isoforms": [ { "isoform_ac": "A0A287B1H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1/entry#A0A287B1H7-1", "sequence": { "sequence": "MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRLLKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSYDDIVTEFGDSACFTLSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKLTSLQNFSNCLPNSCTTLVSNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVISPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPTALSPLTPSFGILPLETPSPGDGSYLQNYTNTSSVIDVPSTGAPSKKSVTRIGQTGTKSVFSQSGNSREVTPILVAQTQSSGPQTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAGLMSLLREMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF", "length": 799, "header": "tr|A0A287B1H7-1|A0A4X1TAL1_PIG Computationally mapped isoform of Cell division cycle protein 27 homolog OS=Sus scrofa OX=9823 GN=CDC27 PE=3 SV=2 CANONICAL=A0A4X1TAL1-1" }, "locus": { "chromosome": "12", "start_pos": 16879333, "end_pos": 16811030, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058263.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058263.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050260.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050260.2" } ] } }, { "isoform_ac": "A0A287BI65-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1/entry#A0A287BI65-1", "sequence": { "sequence": "MSRGWPGRSRYGGGPEALQKVGLSLKDDGAAGTRPVHSEEALFLLATCYYRSGKAYKAYRLLKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSYDDIVTEFGDSACFTLSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKLTSLQNFSNCLPNSCTTLVSNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVISPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPTALSPLTPSFGILPLETPSPGDGSYLQNYTNTSSVIDVPSTGAPSKKSVTRIGQTGTKSVFSQSGNSREVTPILVAQTQSSGPQTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAGLMSLLREMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF", "length": 825, "header": "tr|A0A287BI65-1|A0A4X1TAL1_PIG Computationally mapped isoform of Cell division cycle protein 27 homolog OS=Sus scrofa OX=9823 GN=CDC27 PE=3 SV=1 CANONICAL=A0A4X1TAL1-1" }, "locus": { "chromosome": "12", "start_pos": 16879333, "end_pos": 16810951, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054238.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054238.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056229.1", "url": "https://www.ensembl.org/id/ENSSSCP00000056229.1" } ] } }, { "isoform_ac": "A0A4X1T789-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1/entry#A0A4X1T789-1", "sequence": { "sequence": "MSRGWPGRSRYGGGPEALQKVGLSLKDDGAAGTRPGCYMASTKPLCLQRCSFPRRTTICRRLAEGEQILSGGVFNKQKSYDDIVTEFGDSACFTLSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKLTSLQNFSNCLPNSCTTLVSNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVISPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPTALSPLTPSFGILPLETPSPGDGSYLQNYTNTSSVIDVPSTGAPSKKSVTRIGQTGTKSVFSQSGNSREVTPILVAQTQSSGPQTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAGLMSLLREMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF", "length": 801, "header": "tr|A0A4X1T789-1|A0A4X1T789_PIG Computationally mapped isoform of Cell division cycle protein 27 homolog OS=Sus scrofa OX=9823 GN=CDC27 PE=3 SV=1 CANONICAL=A0A4X1TAL1-1" }, "locus": { "chromosome": "12", "start_pos": 16879333, "end_pos": 16810951, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046519.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046519.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039368.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039368.2" } ] } }, { "isoform_ac": "A0A4X1TAL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1/entry#A0A4X1TAL1-1", "sequence": { "sequence": "MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRLLKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSYDDIVTEFGDSACFTLSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKLTSLQNFSNCLPNSCTTLVSNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVISPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPTALSPLTPSFGILPLETPSPGDGSYLQNYTNTSSVIDVPSTGAPSKKSVTRIGQTGTKSVFSQSGNSREVTPILVAQTQSSGPQTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAGLMSLLREMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF", "length": 824, "header": "tr|A0A4X1TAL1-1|A0A4X1TAL1_PIG Isoform 1 of Cell division cycle protein 27 homolog OS=Sus scrofa OX=9823 GN=CDC27 PE=3 SV=1 CANONICAL=A0A4X1TAL1-1" }, "locus": { "chromosome": "12", "start_pos": 16879333, "end_pos": 16811030, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018844.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018844.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018341.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018341.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BI65", "url": "https://www.uniprot.org/uniprotkb/A0A287BI65" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-SSC-174048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174048", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Cyclin B" }, { "id": "R-SSC-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-SSC-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-SSC-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-SSC-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-SSC-176407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176407", "resource": "Reactome", "description": "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" }, { "id": "R-SSC-176408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176408", "resource": "Reactome", "description": "Regulation of APC/C activators between G1/S and early anaphase" }, { "id": "R-SSC-176409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176409", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of mitotic proteins" }, { "id": "R-SSC-176412", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176412", "resource": "Reactome", "description": "Phosphorylation of the APC/C" }, { "id": "R-SSC-179409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-179409", "resource": "Reactome", "description": "APC-Cdc20 mediated degradation of Nek2A" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2559582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559582", "resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-SSC-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-SSC-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "metaphase/anaphase transition of mitotic cell cycle", "id": "GO:0007091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007091", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "protein branched polyubiquitination", "id": "GO:0141198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141198", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" }, { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TAL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 759, "end_pos": 761, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 759, "end_pos": 761 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RMY4-1", "uniprot_ac": "A0A5G2RMY4", "uniprot_id": "A0A5G2RMY4_PIG", "mass": { "chemical_mass": 58475.0, "monoisotopic_mass": 58475.0 }, "refseq": {}, "gene_names": [ { "name": "BAIAP2", "type": "recommended", "evidence": [ { "id": "A0A5G2RMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ] } ], "protein_names": [ { "name": "BAR/IMD domain-containing adapter protein 2", "type": "recommended", "evidence": [ { "id": "A0A5G2RMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4/entry#names_and_taxonomy" } ] }, { "name": "Brain-specific angiogenesis inhibitor 1-associated protein 2", "type": "synonym", "evidence": [ { "id": "A0A5G2RMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BKX8", "url": "https://www.uniprot.org/uniprotkb/A0A287BKX8#function" }, { "database": "UniProtKB", "id": "ARBA00025545", "url": "https://www.uniprot.org/uniprotkb/ARBA00025545#function" }, { "database": "UniProtKB", "id": "A0A287BRR9", "url": "https://www.uniprot.org/uniprotkb/A0A287BRR9#function" }, { "database": "UniProtKB", "id": "F1RZB0", "url": "https://www.uniprot.org/uniprotkb/F1RZB0#function" }, { "database": "UniProtKB", "id": "A0A5G2QHH7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHH7#function" }, { "database": "UniProtKB", "id": "A0A5G2QK03", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QK03#function" }, { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BAIAP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4", "locus": { "chromosome": "12", "start_pos": 1603540, "end_pos": 1670075, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017142", "url": "https://www.ensembl.org/id/ENSSSCG00000017142" } ] } } ], "crossref": [ { "id": "A0A5G2RMY4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RMY4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017142", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017142", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07646", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07646", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11915", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11915", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513228", "url": "https://www.ncbi.nlm.nih.gov/gene/100513228", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FSHQAKG", "url": "https://omabrowser.org/oma/group/FSHQAKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR14206", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14206", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14206:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14206:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2029482", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2029482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4420097", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4420097", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5663213", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BKX8", "url": "https://www.uniprot.org/uniprotkb/A0A287BKX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BKX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BKX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BRR9", "url": "https://www.uniprot.org/uniprotkb/A0A287BRR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BRR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BRR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHH7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QK03", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QK03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QK03-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QK03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZB0", "url": "https://www.uniprot.org/uniprotkb/F1RZB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZB0-1", "url": "https://www.uniprot.org/uniprotkb/F1RZB0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFVSRRGGGMRFCSCCSTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELESYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAVQLVQQVASSNGSILPSGLSASKSNLVISDPIPGAKPLPVPPELAPFVGVSPRSGNAPVLNGASGPDSEDYSPWAERKAAQPKSASPPQSQSKLSDSYSNTLPVRKSVAPKNSYAATENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKEDLALPPPDYGSASRAFPAQTAGTFKQRPYSVAVPAFSQGLDDYGARAVSRNPFANIQLKPTVTNDRSAPLLS", "length": 534, "header": "tr|A0A5G2RMY4-1|A0A5G2RMY4_PIG Isoform 1 of BAR/IMD domain-containing adapter protein 2 OS=Sus scrofa OX=9823 GN=BAIAP2 PE=1 SV=2 CANONICAL=A0A5G2RMY4-1" }, "isoforms": [ { "isoform_ac": "A0A287BKX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4/entry#A0A287BKX8-1", "sequence": { "sequence": "MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELESYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAVQLVQQVASSNGSILPSGLSASKSNLVISDPIPGAKPLPVPPELAPFVGRLSAQDSAPVLNGASGPDSEDYSPWAERKAAQPKSASPPQSQSKLSDSYSNTLPVRKSVAPKNSYAATENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKEDLALPPPDYGSASRAFPAQTAGTFKQRPYSVAVPAFSQGLDDYGARAVSRNPFANIQLKPTVTNDRSSQKASDSRLGIFSRLRRLRALWLSATTTGTGVASSSLSSLGSWML", "length": 575, "header": "tr|A0A287BKX8-1|A0A5G2RMY4_PIG Computationally mapped isoform of BAR/IMD domain-containing adapter protein 2 OS=Sus scrofa OX=9823 GN=BAIAP2 PE=1 SV=1 CANONICAL=A0A5G2RMY4-1" }, "locus": { "chromosome": "12", "start_pos": 1666830, "end_pos": 1606770, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054836.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054836.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056825.1", "url": "https://www.ensembl.org/id/ENSSSCP00000056825.1" } ] } }, { "isoform_ac": "A0A287BRR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4/entry#A0A287BRR9-1", "sequence": { "sequence": "MSLSRSEEMHRLTENVYKGVEEKCWLVFFPVFPASALKPLNRNFCGENEEGTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELESYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAVQLVQQVASSNGSILPSGLSASKSNLVISDPIPGAKPLPVPPELAPFVGRLSAQDSAPVLNGASGPDSEDYSPWAERKAAQPKSASPPQSQSKLSDSYSNTLPVRKSVAPKNSYAATENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKEDLALPPPDYGSASRAFPAQTAGTFKQRPYSVAVPAFSQGLDDYGARAVSSADVEVARF", "length": 554, "header": "tr|A0A287BRR9-1|A0A5G2RMY4_PIG Computationally mapped isoform of BAR/IMD domain-containing adapter protein 2 OS=Sus scrofa OX=9823 GN=BAIAP2 PE=1 SV=2 CANONICAL=A0A5G2RMY4-1" }, "locus": { "chromosome": "12", "start_pos": 1666830, "end_pos": 1614172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049168.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049168.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059340.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059340.2" } ] } }, { "isoform_ac": "A0A5G2QHH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4/entry#A0A5G2QHH7-1", "sequence": { "sequence": "MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELESYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAVQLVQQVASSNGSILPSGLSASKSNLVISDPIPGAKPLPVPPELAPFVGRLSAQDSAPVLNGASGPDSEDYSPWAERKAAQPKSASPPQSQSKLSDSYSNTLPVRKSVAPKNSYAATENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKEDLALPPPDYGSASRAFPAQTAGTFKQRPYSVAVPAFSQGLDDYGARAVSR", "length": 513, "header": "tr|A0A5G2QHH7-1|A0A5G2QHH7_PIG Computationally mapped isoform of BAR/IMD domain-containing adapter protein 2 OS=Sus scrofa OX=9823 GN=BAIAP2 PE=1 SV=1 CANONICAL=A0A5G2RMY4-1" }, "locus": { "chromosome": "12", "start_pos": 1666830, "end_pos": 1616481, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069593.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069593.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063809.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063809.1" } ] } }, { "isoform_ac": "A0A5G2QK03-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4/entry#A0A5G2QK03-1", "sequence": { "sequence": "MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELESYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAVQLVQQVASSNGSILPSGLSASKSNLVISDPIPGAKPLPVPPELAPFVGVSPRSGNAPVLNGASGPDSEDYSPWAERKAAQPKSASPPQSQSKLSDSYSNTLPVRKSVAPKNSYAATENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKEDLALPPPDYGSASRAFPAQTAGTFKQRPYSVAVPAFSQVSAGHGGAVRVGVVRPWLDKESLVDLGGHPKWRGLLLSLLRAAPPPAPALQPLPHPWAPT", "length": 561, "header": "tr|A0A5G2QK03-1|A0A5G2QK03_PIG Computationally mapped isoform of BAR/IMD domain-containing adapter protein 2 OS=Sus scrofa OX=9823 GN=BAIAP2 PE=1 SV=2 CANONICAL=A0A5G2RMY4-1" }, "locus": { "chromosome": "12", "start_pos": 1666830, "end_pos": 1616544, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085002.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085002.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065131.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065131.2" } ] } }, { "isoform_ac": "A0A5G2RMY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4/entry#A0A5G2RMY4-1", "sequence": { "sequence": "MFVSRRGGGMRFCSCCSTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELESYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAVQLVQQVASSNGSILPSGLSASKSNLVISDPIPGAKPLPVPPELAPFVGVSPRSGNAPVLNGASGPDSEDYSPWAERKAAQPKSASPPQSQSKLSDSYSNTLPVRKSVAPKNSYAATENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKEDLALPPPDYGSASRAFPAQTAGTFKQRPYSVAVPAFSQGLDDYGARAVSRNPFANIQLKPTVTNDRSAPLLS", "length": 534, "header": "tr|A0A5G2RMY4-1|A0A5G2RMY4_PIG Isoform 1 of BAR/IMD domain-containing adapter protein 2 OS=Sus scrofa OX=9823 GN=BAIAP2 PE=1 SV=2 CANONICAL=A0A5G2RMY4-1" }, "locus": { "chromosome": "12", "start_pos": 1665586, "end_pos": 1610846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072939.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072939.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074060.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074060.2" } ] } }, { "isoform_ac": "F1RZB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4/entry#F1RZB0-1", "sequence": { "sequence": "MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELESYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAVQLVQQVASSNGSILPSGLSASKSNLVISDPIPGAKPLPVPPELAPFVGRLSAQDSAPVLNGASGPDSEDYSPWAERKAAQPKSASPPQSQSKLSDSYSNTLPVRKSVAPKNSYAATENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKEDLALPPPDYGSASRAFPAQTAGTFKQRPYSVAVPAFSQGLDDYGARAVSSGSGTLVSTV", "length": 522, "header": "tr|F1RZB0-1|A0A5G2RMY4_PIG Computationally mapped isoform of BAR/IMD domain-containing adapter protein 2 OS=Sus scrofa OX=9823 GN=BAIAP2 PE=1 SV=3 CANONICAL=A0A5G2RMY4-1" }, "locus": { "chromosome": "12", "start_pos": 1666830, "end_pos": 1615846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018662.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018662.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018161.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018161.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BKX8", "url": "https://www.uniprot.org/uniprotkb/A0A287BKX8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2029482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2029482", "resource": "Reactome", "description": "Regulation of actin dynamics for phagocytic cup formation" }, { "id": "R-SSC-4420097", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4420097", "resource": "Reactome", "description": "VEGFA-VEGFR2 Pathway" }, { "id": "R-SSC-5663213", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663213", "resource": "Reactome", "description": "RHO GTPases Activate WASPs and WAVEs" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-SSC-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6GMN2-1", "protein_name": "BAR/IMD domain-containing adapter protein 2", "gene_name": "Baiap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTFAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKAFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAAQLMQQMANSNGSILPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQENVPVMNGVAGADSEDYNPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLALPPPDYGTSSRAFPSQTAGTFKQRPYSVAVPAFSQGLDDYGARSVSRNPFANVHLKPTVTNDRSAPLLS", "length": 535 }, "evidence": [ { "id": "A0A5G2RMY4", "url": "https://omabrowser.org/oma/group/A0A5G2RMY4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BKX1-1", "protein_name": "BAR/IMD domain-containing adapter protein 2", "gene_name": "Baiap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTFAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEETLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAVQLMQQMANSNGSILPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQENVPVMNGVAGPDSEDYNPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLALPPPDYGTSSRAFPTQTAGTFKQRPYSVAVPAFSQGLDDYGARSVSRNPFANVHLKPTVTNDRSAPLLS", "length": 535 }, "evidence": [ { "id": "A0A5G2RMY4", "url": "https://omabrowser.org/oma/group/A0A5G2RMY4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UQB8-1", "protein_name": "BAR/IMD domain-containing adapter protein 2", "gene_name": "BAIAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPAQTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDRCDLSAQGPEGREHGDGSARTLAGR", "length": 552 }, "evidence": [ { "id": "A0A5G2RMY4", "url": "https://omabrowser.org/oma/group/A0A5G2RMY4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "filopodium", "id": "GO:0030175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030175", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "filopodium assembly", "id": "GO:0046847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046847", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "actin crosslink formation", "id": "GO:0051764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051764", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "positive regulation of actin filament polymerization", "id": "GO:0030838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030838", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "cytoskeletal anchor activity", "id": "GO:0008093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008093", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" }, { "name": "proline-rich region binding", "id": "GO:0070064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070064", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMY4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RMY4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 534, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RMY4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RMY4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" }, { "id": "PS51338", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51338" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IMD", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 249, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMY4" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 374, "end_pos": 437, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 250, "end_pos": 252 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 390, "end_pos": 392 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RNB8-1", "uniprot_ac": "A0A5G2RNB8", "uniprot_id": "A0A5G2RNB8_PIG", "mass": { "chemical_mass": 50593.0, "monoisotopic_mass": 50593.0 }, "refseq": {}, "gene_names": [ { "name": "PDCD4", "type": "recommended", "evidence": [ { "id": "A0A5G2RNB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ] } ], "protein_names": [ { "name": "Programmed cell death protein 4", "type": "recommended", "evidence": [ { "id": "A0A5G2RNB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8#function" }, { "database": "UniProtKB", "id": "ARBA00054494", "url": "https://www.uniprot.org/uniprotkb/ARBA00054494#function" }, { "database": "UniProtKB", "id": "A0A4X1TDX8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDX8#function" }, { "database": "UniProtKB", "id": "A0A8D0XM80", "url": "https://www.uniprot.org/uniprotkb/A0A8D0XM80#function" }, { "database": "UniProtKB", "id": "A0A8D0XIM9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0XIM9#function" }, { "database": "UniProtKB", "id": "A0A4X1TG29", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG29#function" }, { "database": "UniProtKB", "id": "A0A5G2QV27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV27#function" }, { "database": "UniProtKB", "id": "F1S5L7", "url": "https://www.uniprot.org/uniprotkb/F1S5L7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PDCD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8", "locus": { "chromosome": "14", "start_pos": 121338740, "end_pos": 121305629, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010627", "url": "https://www.ensembl.org/id/ENSSSCG00000010627" } ] } } ], "crossref": [ { "id": "A0A5G2RNB8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RNB8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010627", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010627", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100157112", "url": "https://www.ncbi.nlm.nih.gov/gene/100157112", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157112", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157112", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TG29", "url": "https://www.orthodb.org/?gene=A0A4X1TG29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12626", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12626", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12626:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12626:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1TDX8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TDX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TG29", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TG29-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QV27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QV27-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QV27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RNB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0XIM9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0XIM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0XIM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0XIM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0XM80", "url": "https://www.uniprot.org/uniprotkb/A0A8D0XM80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0XM80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0XM80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5L7", "url": "https://www.uniprot.org/uniprotkb/F1S5L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5L7-1", "url": "https://www.uniprot.org/uniprotkb/F1S5L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVENEQILNVTPTDEENAGTEEIKNEINGNWISASSINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEGLRSGVTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDEMAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKELPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGRRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITLDQMKRGYERIYNEIPDINLDVPHSYSMLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY", "length": 457, "header": "tr|A0A5G2RNB8-1|A0A5G2RNB8_PIG Isoform 1 of Programmed cell death protein 4 OS=Sus scrofa OX=9823 GN=PDCD4 PE=1 SV=1 CANONICAL=A0A5G2RNB8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TDX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8/entry#A0A4X1TDX8-1", "sequence": { "sequence": "MDVENEQILNVTPTDPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEGLRSGVTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDEMAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKELPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGRRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITLDQMKRGQKTFCK", "length": 410, "header": "tr|A0A4X1TDX8-1|A0A4X1TDX8_PIG Computationally mapped isoform of Programmed cell death protein 4 OS=Sus scrofa OX=9823 GN=PDCD4 PE=1 SV=1 CANONICAL=A0A5G2RNB8-1" }, "locus": { "chromosome": "14", "start_pos": 121334055, "end_pos": 121310383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063953.1", "url": "https://www.ensembl.org/id/ENSSSCT00000063953.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051777.1", "url": "https://www.ensembl.org/id/ENSSSCP00000051777.1" } ] } }, { "isoform_ac": "A0A4X1TG29-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8/entry#A0A4X1TG29-1", "sequence": { "sequence": "MDVENEQILNVTPTDPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEGLRSGVTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDEMAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKELPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGRRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITLDQMKRGYERIYNEIPDINLDVPHSYSMLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY", "length": 469, "header": "tr|A0A4X1TG29-1|A0A5G2RNB8_PIG Computationally mapped isoform of Programmed cell death protein 4 OS=Sus scrofa OX=9823 GN=PDCD4 PE=1 SV=1 CANONICAL=A0A5G2RNB8-1" }, "locus": { "chromosome": "14", "start_pos": 121334092, "end_pos": 121310383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041632.2", "url": "https://www.ensembl.org/id/ENSSSCT00000041632.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044229.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044229.1" } ] } }, { "isoform_ac": "A0A5G2QQN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8/entry#A0A5G2QQN3-1", "sequence": { "sequence": "MDVENEQILNVTPTDPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEGLRSGVTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDEMAFEKTLTPIIQEYFEHGDTNEVALVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGRRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITLDQMKRGYERIYNEIPDINLDVPHSYSMLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY", "length": 395, "header": "tr|A0A5G2QQN3-1|A0A5G2RNB8_PIG Computationally mapped isoform of Programmed cell death protein 4 OS=Sus scrofa OX=9823 GN=PDCD4 PE=1 SV=1 CANONICAL=A0A5G2RNB8-1" }, "locus": { "chromosome": "14", "start_pos": 121334092, "end_pos": 121310383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082647.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082647.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067048.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067048.1" } ] } }, { "isoform_ac": "A0A5G2QV27-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8/entry#A0A5G2QV27-1", "sequence": { "sequence": "MSKNPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEGLRSGVTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDEMAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKELPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGRRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITLDQMKRGYERIYNEIPDINLDVPHSYSMLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY", "length": 458, "header": "tr|A0A5G2QV27-1|A0A5G2RNB8_PIG Computationally mapped isoform of Programmed cell death protein 4 OS=Sus scrofa OX=9823 GN=PDCD4 PE=1 SV=1 CANONICAL=A0A5G2RNB8-1" }, "locus": { "chromosome": "14", "start_pos": 121334092, "end_pos": 121311936, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082905.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082905.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068693.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068693.1" } ] } }, { "isoform_ac": "A0A5G2RNB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8/entry#A0A5G2RNB8-1", "sequence": { "sequence": "MDVENEQILNVTPTDEENAGTEEIKNEINGNWISASSINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEGLRSGVTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDEMAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKELPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGRRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITLDQMKRGYERIYNEIPDINLDVPHSYSMLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY", "length": 457, "header": "tr|A0A5G2RNB8-1|A0A5G2RNB8_PIG Isoform 1 of Programmed cell death protein 4 OS=Sus scrofa OX=9823 GN=PDCD4 PE=1 SV=1 CANONICAL=A0A5G2RNB8-1" }, "locus": { "chromosome": "14", "start_pos": 121334092, "end_pos": 121310383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085252.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085252.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074305.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074305.1" } ] } }, { "isoform_ac": "A0A8D0XIM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8/entry#A0A8D0XIM9-1", "sequence": { "sequence": "MFYDLNTEIKNEINGNWISASSINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEGLRSGVTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDEMAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKELPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGRRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITLDQMKRGYERIYNEIPDINLDVPHSYSMLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY", "length": 442, "header": "tr|A0A8D0XIM9-1|A0A5G2RNB8_PIG Computationally mapped isoform of Programmed cell death protein 4 OS=Sus scrofa OX=9823 GN=PDCD4 PE=1 SV=1 CANONICAL=A0A5G2RNB8-1" }, "locus": { "chromosome": "14", "start_pos": 121334092, "end_pos": 121316320, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067945.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067945.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072208.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072208.1" } ] } }, { "isoform_ac": "A0A8D0XM80-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8/entry#A0A8D0XM80-1", "sequence": { "sequence": "NPAGNHEVVDPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEGLRSGVTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDEMAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKELPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGRRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITLDQMKRGYERIYNEIPDINLDVPHSYSMLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY", "length": 464, "header": "tr|A0A8D0XM80-1|A0A5G2RNB8_PIG Computationally mapped isoform of Programmed cell death protein 4 OS=Sus scrofa OX=9823 GN=PDCD4 PE=1 SV=1 CANONICAL=A0A5G2RNB8-1" }, "locus": { "chromosome": "14", "start_pos": 121334092, "end_pos": 121315668, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051692.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051692.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058733.3", "url": "https://www.ensembl.org/id/ENSSSCP00000058733.3" } ] } }, { "isoform_ac": "F1S5L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8/entry#F1S5L7-1", "sequence": { "sequence": "MTKVPNPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEGLRSGVTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDEMAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKELPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGRRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITLDQMKRGYERIYNEIPDINLDVPHSYSMLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY", "length": 460, "header": "tr|F1S5L7-1|A0A5G2RNB8_PIG Computationally mapped isoform of Programmed cell death protein 4 OS=Sus scrofa OX=9823 GN=PDCD4 PE=1 SV=4 CANONICAL=A0A5G2RNB8-1" }, "locus": { "chromosome": "14", "start_pos": 121334092, "end_pos": 121316153, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011623.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011623.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011321.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011321.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 114, "start_aa": "Thr", "end_pos": 114, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr114", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TG29", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG29" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157112", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157112", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" }, { "name": "negative regulation of myofibroblast differentiation", "id": "GO:1904761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904761", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" }, { "name": "negative regulation of vascular associated smooth muscle cell differentiation", "id": "GO:1905064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905064", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" }, { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" }, { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response", "id": "GO:0050729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050729", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" }, { "name": "negative regulation of cytokine production involved in inflammatory response", "id": "GO:1900016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900016", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell apoptotic process", "id": "GO:2000353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000353", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" }, { "name": "negative regulation of vascular associated smooth muscle cell proliferation", "id": "GO:1904706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904706", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" }, { "name": "positive regulation of vascular associated smooth muscle cell apoptotic process", "id": "GO:1905461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905461", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNB8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RNB8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 457, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RNB8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RNB8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RNB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNB8" }, { "id": "PS51366", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51366" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MI", "eco_id": "ECO_0000259", "start_pos": 151, "end_pos": 272, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 114 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 54, "end_pos": 56 }, { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T3R0-1", "uniprot_ac": "A0A4X1T3R0", "uniprot_id": "A0A4X1T3R0_PIG", "mass": { "chemical_mass": 24121.0, "monoisotopic_mass": 24121.0 }, "refseq": { "ac": "NP_001230567", "name": "maleylacetoacetate isomerase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230567" }, "gene_names": [ { "name": "GSTZ1", "type": "recommended", "evidence": [ { "id": "A0A4X1T3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0" } ] }, { "name": "GSTZ1", "type": "synonym", "evidence": [ { "id": "NP_001230567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230567" } ] } ], "protein_names": [ { "name": "Maleylacetoacetate isomerase", "type": "recommended", "evidence": [ { "id": "A0A4X1T3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.18", "type": "synonym", "evidence": [ { "id": "A0A4X1T3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#names_and_taxonomy" } ] }, { "name": "5.2.1.2", "type": "synonym", "evidence": [ { "id": "A0A4X1T3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#names_and_taxonomy" } ] }, { "name": "GSTZ1-1", "type": "synonym", "evidence": [ { "id": "A0A4X1T3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#names_and_taxonomy" } ] }, { "name": "Glutathione S-transferase zeta 1", "type": "synonym", "evidence": [ { "id": "A0A4X1T3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#names_and_taxonomy" } ] }, { "name": "glutathione transferase zeta 1", "type": "synonym", "evidence": [ { "id": "NP_001230567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230567" } ] }, { "name": "maleylacetoacetate isomerase", "type": "synonym", "evidence": [ { "id": "NP_001230567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230567" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GSTZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0", "locus": { "chromosome": "7", "start_pos": 100408420, "end_pos": 100392271, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002396", "url": "https://www.ensembl.org/id/ENSSSCG00000002396" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002396", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002396", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03042", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03191", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03191", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626791", "url": "https://www.ncbi.nlm.nih.gov/gene/100626791", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005955", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005955", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626791", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626791", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VYNAHRF", "url": "https://omabrowser.org/oma/group/VYNAHRF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T3R0", "url": "https://www.orthodb.org/?gene=A0A4X1T3R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2R0R7", "url": "https://www.orthodb.org/?gene=A0A5G2R0R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "K7GQV5", "url": "https://www.orthodb.org/?gene=K7GQV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42673", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42673", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42673:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42673:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14497", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14497", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156590", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-204174", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204174", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8963684", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8963684", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230567", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230567", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "14817", "url": "https://www.rhea-db.org/rhea/14817", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "16437", "url": "https://www.rhea-db.org/rhea/16437", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T3R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T3R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0R7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RHC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RHC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0WDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WDQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0WDQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WDQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEL3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMV3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2N0", "url": "https://www.uniprot.org/uniprotkb/F1S2N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2N0-1", "url": "https://www.uniprot.org/uniprotkb/F1S2N0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GQV5", "url": "https://www.uniprot.org/uniprotkb/K7GQV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GQV5-1", "url": "https://www.uniprot.org/uniprotkb/K7GQV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQAGKPILYSYFRSSCSWRVRIALALKNIDYEIVAINLIKDGGQQFSKEFQALNPMKQVPALKIDGITLSQSLAIIEYLEETRPTPRLLPQDPKKRAQVRMISDLLASGIQPLQNLSVLNQVGKENQLTWAQRVIAPGFNALEQILQSTAGKYCMGDEVSMADLCLVPQVANAERYKVDLSPYPTISRINKSLLALEAFQVSHPSRQPDTPPELRA", "length": 216, "header": "tr|A0A4X1T3R0-1|A0A4X1T3R0_PIG Isoform 1 of Maleylacetoacetate isomerase OS=Sus scrofa OX=9823 GN=GSTZ1 PE=1 SV=1 CANONICAL=A0A4X1T3R0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T3R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#A0A4X1T3R0-1", "sequence": { "sequence": "MQAGKPILYSYFRSSCSWRVRIALALKNIDYEIVAINLIKDGGQQFSKEFQALNPMKQVPALKIDGITLSQSLAIIEYLEETRPTPRLLPQDPKKRAQVRMISDLLASGIQPLQNLSVLNQVGKENQLTWAQRVIAPGFNALEQILQSTAGKYCMGDEVSMADLCLVPQVANAERYKVDLSPYPTISRINKSLLALEAFQVSHPSRQPDTPPELRA", "length": 216, "header": "tr|A0A4X1T3R0-1|A0A4X1T3R0_PIG Isoform 1 of Maleylacetoacetate isomerase OS=Sus scrofa OX=9823 GN=GSTZ1 PE=1 SV=1 CANONICAL=A0A4X1T3R0-1" }, "locus": { "chromosome": "7", "start_pos": 100402518, "end_pos": 100392395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036355.4", "url": "https://www.ensembl.org/id/ENSSSCT00000036355.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028938.2", "url": "https://www.ensembl.org/id/ENSSSCP00000028938.2" } ] } }, { "isoform_ac": "A0A5G2QKN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#A0A5G2QKN3-1", "sequence": { "sequence": "LQPILYSYFRSSCSWRVRIALALKNIDYEIVAINLIKDGGQQFSKEFQALNPMKQVPALKIDGITLSQSNLSVLNQVGKENQLTWAQRVIAPGFNALEQILQSTAGKYCMGDEVSMADLCLVPQVANAERYKVDLSPYPTISRINKSLLALEAFQVSHPSRQPDTPPELRA", "length": 171, "header": "tr|A0A5G2QKN3-1|A0A4X1T3R0_PIG Computationally mapped isoform of Maleylacetoacetate isomerase OS=Sus scrofa OX=9823 GN=GSTZ1 PE=1 SV=2 CANONICAL=A0A4X1T3R0-1" }, "locus": { "chromosome": "7", "start_pos": 100402518, "end_pos": 100395843, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080567.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080567.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062622.2", "url": "https://www.ensembl.org/id/ENSSSCP00000062622.2" } ] } }, { "isoform_ac": "A0A5G2R0R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#A0A5G2R0R7-1", "sequence": { "sequence": "MKQVPALKIDGITLSQSLAIIEYLEETRPTPRLLPQDPKKRAQVRMISDLLASGIQPLQNLSVLNQVGKENQLTWAQRVIAPGFNALEQILQSTAGKYCMGDEVSMADLCLVPQVANAERYKVDLSPYPTISRINKSLLALEAFQVSHPSRQPDTPPELRA", "length": 161, "header": "tr|A0A5G2R0R7-1|A0A4X1T3R0_PIG Computationally mapped isoform of Maleylacetoacetate isomerase OS=Sus scrofa OX=9823 GN=GSTZ1 PE=1 SV=1 CANONICAL=A0A4X1T3R0-1" }, "locus": { "chromosome": "7", "start_pos": 100402518, "end_pos": 100398649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070698.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070698.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067801.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067801.1" } ] } }, { "isoform_ac": "A0A5G2RHC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#A0A5G2RHC5-1", "sequence": { "sequence": "KLDQWLSPDRCLLSLLALALKNIDYEIVAINLIKDGGQQFSKEFQALNPMKQVPALKIDGITLSQSLAIIEYLEETRPTPRLLPQDPKKRAQVRMISDLLASGIQPLQNLSVLNQVGKENQLTWAQRVIAPGFNALEQILQSTAGKYCMGDEVSMADLCLVPQVANAERYKVDLSPYPTISRINKSLLALEAFQVSHPSRQPDTPPELRA", "length": 210, "header": "tr|A0A5G2RHC5-1|A0A5G2RHC5_PIG Computationally mapped isoform of maleylacetoacetate isomerase OS=Sus scrofa OX=9823 GN=GSTZ1 PE=1 SV=1 CANONICAL=A0A4X1T3R0-1" }, "locus": { "chromosome": "7", "start_pos": 100402518, "end_pos": 100397734, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085382.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085382.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070726.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070726.1" } ] } }, { "isoform_ac": "A0A8D0WDQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#A0A8D0WDQ9-1", "sequence": { "sequence": "MTFEPRQPASRSLALTGSHPAQPTFSYSHVVLAGIRRQEHWSRTCFSKKTPSRALALKNIDYEIVAINLIKDGGQQFSKEFQALNPMKQVPALKIDGITLSQSLAIIEYLEETRPTPRLLPQDPKKRAQVRMISDLLASGIQPLQNLSVLNQVGKENQLTWAQRVIAPGFNALEQILQSTAGKYCMGDEVSMADLCLVPQVANAERYKVDLSPYPTISRINKSLLALEAFQVSHPSRQPDTPPELRA", "length": 247, "header": "tr|A0A8D0WDQ9-1|A0A4X1T3R0_PIG Computationally mapped isoform of Maleylacetoacetate isomerase OS=Sus scrofa OX=9823 GN=GSTZ1 PE=1 SV=1 CANONICAL=A0A4X1T3R0-1" }, "locus": { "chromosome": "7", "start_pos": 100402518, "end_pos": 100396831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071846.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071846.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073069.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073069.1" } ] } }, { "isoform_ac": "A0A8W4FEL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#A0A8W4FEL3-1", "sequence": { "sequence": "VLSPQPILYSYFRSSCSWRVRIALALKNIDYEIVAINLIKDGGQQFSKEFQALNPMKQVPALKIDGITLSQSNLSVLNQVGKENQLTWAQRVIAPGFNALEQILQSTAGKYCMGDEVSMADLCLVPQVANAERYKVDLSPYPTISRINKSLLALEAFQVSHPSRQPDTPPELRA", "length": 174, "header": "tr|A0A8W4FEL3-1|A0A4X1T3R0_PIG Computationally mapped isoform of Maleylacetoacetate isomerase OS=Sus scrofa OX=9823 GN=GSTZ1 PE=1 SV=1 CANONICAL=A0A4X1T3R0-1" }, "locus": { "chromosome": "7", "start_pos": 100402518, "end_pos": 100396043, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095900.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095900.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076750.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076750.1" } ] } }, { "isoform_ac": "A0A8W4FMV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#A0A8W4FMV3-1", "sequence": { "sequence": "KCAQWLSPDRCLLSLLALALKNIDYEIVAINLIKDGGQQFSKEFQALNPMKQVPALKIDGITLSQSLAIIEYLEETRPTPRLLPQDPKKRAQVRMISDLLASGIQPLQNLSVLNQVGKENQLTWAQRVIAPGFNALEQILQSTAGKYCMGDEVSMADLCLVPQVANAERYKVDLSPYPTISRINKSLLALEAFQVSHPSRQPDTPPELRA", "length": 210, "header": "tr|A0A8W4FMV3-1|A0A4X1T3R0_PIG Computationally mapped isoform of Maleylacetoacetate isomerase OS=Sus scrofa OX=9823 GN=GSTZ1 PE=1 SV=1 CANONICAL=A0A4X1T3R0-1" }, "locus": { "chromosome": "7", "start_pos": 100402518, "end_pos": 100397805, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106287.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106287.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080684.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080684.1" } ] } }, { "isoform_ac": "F1S2N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#F1S2N0-1", "sequence": { "sequence": "VLSPQPILYSYFRSSCSWRVRIALALKNIDYEIVAINLIKDGGQQLAIIEYLEETRPTPRLLPQDPKKRAQVRMISDLLASGIQPLQNLSVLNQVGKENQLTWAQRVIAPGFNALEQILQSTAGKYCMGDEVSMADLCLVPQVANAERYKVDLSPYPTISRINKSLLALEAFQVSHPSRQPDTPPELRA", "length": 189, "header": "tr|F1S2N0-1|A0A4X1T3R0_PIG Computationally mapped isoform of Maleylacetoacetate isomerase OS=Sus scrofa OX=9823 GN=GSTZ1 PE=1 SV=4 CANONICAL=A0A4X1T3R0-1" }, "locus": { "chromosome": "7", "start_pos": 100402518, "end_pos": 100396043, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002664.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002664.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002597.4", "url": "https://www.ensembl.org/id/ENSSSCP00000002597.4" } ] } }, { "isoform_ac": "K7GQV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0/entry#K7GQV5-1", "sequence": { "sequence": "MAESSKPILYSYFRSSCSWRVRIALALKNIDYEIVAINLIKDGGQQFSKEFQALNPMKQVPALKIDGITLSQSLAIIEYLEETRPTPRLLPQDPKKRAQVRMISDLLASGIQPLQNLSVLNQVGKENQLTWAQRVIAPGFNALEQILQSTAGKYCMGDEVSMADLCLVPQVANAERYKVDLSPYPTISRINKSLLALEAFQVSHPSRQPDTPPELRA", "length": 217, "header": "tr|K7GQV5-1|A0A4X1T3R0_PIG Computationally mapped isoform of Maleylacetoacetate isomerase OS=Sus scrofa OX=9823 GN=GSTZ1 PE=1 SV=1 CANONICAL=A0A4X1T3R0-1" }, "locus": { "chromosome": "7", "start_pos": 100402518, "end_pos": 100395812, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033132.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033132.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030279.1", "url": "https://www.ensembl.org/id/ENSSSCP00000030279.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QKN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKN3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626791", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626791", "resource": "KEGG Pathway" }, { "id": "R-SSC-156590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156590", "resource": "Reactome", "description": "Glutathione conjugation" }, { "id": "R-SSC-204174", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204174", "resource": "Reactome", "description": "Regulation of pyruvate dehydrogenase (PDH) complex" }, { "id": "R-SSC-8963684", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8963684", "resource": "Reactome", "description": "Tyrosine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "O43708-1", "protein_name": "Maleylacetoacetate isomerase", "gene_name": "GSTZ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQAGKPILYSYFRSSCSWRVRIALALKGIDYKTVPINLIKDRGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDLTPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA", "length": 216 }, "evidence": [ { "id": "A0A4X1T3R0", "url": "https://omabrowser.org/oma/group/A0A4X1T3R0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P57113-1", "protein_name": "Maleylacetoacetate isomerase", "gene_name": "Gstz1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQAGKPVLYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFSEEFQTLNPMKQVPALKIDGITIGQSLAILEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMPWAQKAITSGFNALEKILQSTAGKYCVGDEVSMADVCLAPQVANAERFKVDLSPYPTISHINKALLALEAFQVSHPCRQPDTPAELRT", "length": 216 }, "evidence": [ { "id": "A0A4X1T3R0", "url": "https://omabrowser.org/oma/group/A0A4X1T3R0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54YN2-1", "protein_name": "Maleylacetoacetate isomerase", "gene_name": "mai", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTENKTVLYSYWRSSCSWRVRVALAYKKIKYEYKAIHLLKDGGQQKSDEYSKLNPMKAIPTLEIDGHIIGQSLAILEYLEETHPENPLMPKGSYERAIARQMMQIIGSDIQPLQNLKVLGLIAQYSGDDSKKSEWARTVITNGFNGLEKLLEKHSGKFCVGDSVSFADLCLPAQVYNANRFNVDMTPYPNITRVNQHLLTIPEFIEALPQNQPDAEPQC", "length": 219 }, "evidence": [ { "id": "A0A4X1T3R0", "url": "https://omabrowser.org/oma/group/A0A4X1T3R0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VHD3-1", "protein_name": "Probable maleylacetoacetate isomerase 1", "gene_name": "GstZ1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASATQLTHRGIHLAGLYRSSWSKPLFRHLATKPILYSYWPSSCSWRVRVALAIKKIDYDIKPTSLLKTVSGHAYTDEYREVNPMQKVPSLKIDGHTLCDSVAIIHYLEETRPQPALLPQDPVKRAKIREIVELICSGIQPLQNVSVLDHIGKDQSLQWAQHWISRGFQGLEKVLSHSAGKFCVGDELSMADICLVPQVRNARRYKADLTPYPTIVRLNQELQELDVFKATHPSTQPDCPPEFAKK", "length": 246 }, "evidence": [ { "id": "A0A4X1T3R0", "url": "https://omabrowser.org/oma/group/A0A4X1T3R0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WVL0-1", "protein_name": "Maleylacetoacetate isomerase", "gene_name": "Gstz1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTISHINKELLALEVFQVSHPRRQPDTPAELRT", "length": 216 }, "evidence": [ { "id": "A0A4X1T3R0", "url": "https://omabrowser.org/oma/group/A0A4X1T3R0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ZVQ3-1", "protein_name": "Glutathione S-transferase Z1", "gene_name": "GSTZ1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MANSGEEKLKLYSYWRSSCAHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVDGDVVINDSFAIIMYLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIRYIEEKINVEEKTAWVNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIHGAINRFQINMEPYPTLAKCYESYNELPAFQNALPEKQPDAPSSTI", "length": 221 }, "evidence": [ { "id": "A0A4X1T3R0", "url": "https://omabrowser.org/oma/group/A0A4X1T3R0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0" } ], "pmid": "" }, { "name": "maleylacetoacetate isomerase activity", "id": "GO:0016034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016034", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "L-phenylalanine catabolic process", "id": "GO:0006559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006559", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0" } ], "pmid": "" }, { "name": "L-tyrosine catabolic process", "id": "GO:0006572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006572", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14817", "name": "", "equation": "4-maleylacetoacetate = 4-fumarylacetoacetate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "14817", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14817" } ] }, { "id": "16437", "name": "", "equation": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16437", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16437" } ] }, { "id": "R-SSC-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-176054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176054" } ] }, { "id": "R-SSC-71173", "name": "GSTZ1 isomerizes 4-MAA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-71173", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71173" } ] }, { "id": "R-SSC-9011595", "name": "GSTZ1 dimer dehalogenates DCA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-9010792" ], "output_participant_list": [ "R-ALL-9861558", "R-ALL-9861569" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9011595", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9011595" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9010792", "participant_name": "DCA [mitochondrial matrix]", "crossref": [ { "id": "4518", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "28240", "database": "ChEBI", "url": "" }, { "id": "PDBC02868", "database": "PharmacoDB", "url": "" }, { "id": "0024306", "database": "Mondo", "url": "" } ] }, { "participant_id": "R-ALL-9861558", "participant_name": "Cl- [mitochondrial matrix]", "crossref": [ { "id": "C00115", "database": "COMPOUND", "url": "" }, { "id": "17996", "database": "ChEBI", "url": "" }, { "id": "HMDB0000492", "database": "HMDB Metabolite", "url": "" }, { "id": "8145194", "database": "PubChem Substance", "url": "" } ] }, { "participant_id": "R-ALL-9861569", "participant_name": "GS-MCA [mitochondrial matrix]", "crossref": [ { "id": "229639", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0" }, { "id": "PS50405", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50405" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST C-terminal", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 212, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3R0" }, { "id": "PS50404", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50404" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST N-terminal", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 87, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 190, "end_pos": 192 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SM17-1", "uniprot_ac": "A0A4X1SM17", "uniprot_id": "A0A4X1SM17_PIG", "mass": { "chemical_mass": 61645.0, "monoisotopic_mass": 61645.0 }, "refseq": { "ac": "XP_001928394", "name": "DDB1- and CUL4-associated factor 11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928394" }, "gene_names": [ { "name": "DCAF11", "type": "recommended", "evidence": [ { "id": "A0A4X1SM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17" } ] }, { "name": "DCAF11", "type": "synonym", "evidence": [ { "id": "XP_001928394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928394" } ] } ], "protein_names": [ { "name": "DDB1- and CUL4-associated factor 11", "type": "recommended", "evidence": [ { "id": "A0A4X1SM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17/entry#names_and_taxonomy" } ] }, { "name": "DDB1- and CUL4-associated factor 11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001928394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928394" } ] } ], "function": [ { "annotation": "May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH85#function" }, { "database": "UniProtKB", "id": "ARBA00002614", "url": "https://www.uniprot.org/uniprotkb/ARBA00002614#function" }, { "database": "UniProtKB", "id": "PIRNR038135", "url": "https://www.uniprot.org/uniprotkb/PIRNR038135#function" }, { "database": "UniProtKB", "id": "A0A4X1SM17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DCAF11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17", "locus": { "chromosome": "7", "start_pos": 75168992, "end_pos": 75180953, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002008", "url": "https://www.ensembl.org/id/ENSSSCG00000002008" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002008", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002008", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100157270", "url": "https://www.ncbi.nlm.nih.gov/gene/100157270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157270", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157270", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EHTFPQM", "url": "https://omabrowser.org/oma/group/EHTFPQM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SM17", "url": "https://www.orthodb.org/?gene=A0A4X1SM17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19847", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19847", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19847:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19847:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001928394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928394", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SM17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SM17-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RH85", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RH85-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0IZ08", "url": "https://www.uniprot.org/uniprotkb/A0A8D0IZ08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0IZ08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0IZ08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1GPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GPS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1GPS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GPS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSRNSSSAGTGSGDPSEGLPRRGAGLRRSEEEEEEDEDVDLAQVLAYLLRRGQVRLVQGGGAANLQLIQALSDSEEEHDNAWDGRLGDRYNPPVDATPDTRDLECSEIKTQVELATGRLGHRRAAREHSFPQMLLQRERGLCHRGSFSLGEQSRVMSHFLPNDLGFIDTYSQKAFCGIYSKDGQIFMSACQDQVIRMYDCRYGRFHKFKSIKARDVGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPVERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADMSSQILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGMEASRQAATQQDWDYRWQQVPKKAWRKLKLPGDSSLMTYRGHGVLHTLIRCRFSPTYSTGQQYIYSGCSTGKVVVYDLLSGHIVKKLTSHKACVRDVSWHPFEEKIVSSSWDGNLRLWQYRQAEYFQDDMPESEEHPSSPASVSHPSTAFSSPQ", "length": 546, "header": "tr|A0A4X1SM17-1|A0A4X1SM17_PIG Isoform 1 of DDB1- and CUL4-associated factor 11 OS=Sus scrofa OX=9823 GN=DCAF11 PE=3 SV=1 CANONICAL=A0A4X1SM17-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SM17-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17/entry#A0A4X1SM17-1", "sequence": { "sequence": "MGSRNSSSAGTGSGDPSEGLPRRGAGLRRSEEEEEEDEDVDLAQVLAYLLRRGQVRLVQGGGAANLQLIQALSDSEEEHDNAWDGRLGDRYNPPVDATPDTRDLECSEIKTQVELATGRLGHRRAAREHSFPQMLLQRERGLCHRGSFSLGEQSRVMSHFLPNDLGFIDTYSQKAFCGIYSKDGQIFMSACQDQVIRMYDCRYGRFHKFKSIKARDVGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPVERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADMSSQILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGMEASRQAATQQDWDYRWQQVPKKAWRKLKLPGDSSLMTYRGHGVLHTLIRCRFSPTYSTGQQYIYSGCSTGKVVVYDLLSGHIVKKLTSHKACVRDVSWHPFEEKIVSSSWDGNLRLWQYRQAEYFQDDMPESEEHPSSPASVSHPSTAFSSPQ", "length": 546, "header": "tr|A0A4X1SM17-1|A0A4X1SM17_PIG Isoform 1 of DDB1- and CUL4-associated factor 11 OS=Sus scrofa OX=9823 GN=DCAF11 PE=3 SV=1 CANONICAL=A0A4X1SM17-1" }, "locus": { "chromosome": "7", "start_pos": 75180222, "end_pos": 75171936, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058228.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058228.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050671.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050671.1" } ] } }, { "isoform_ac": "A0A5G2RH85-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17/entry#A0A5G2RH85-1", "sequence": { "sequence": "MTMPGMVVSETDTTHLWMPPLTPGTWNAVRSRHRWNWPQGGDIDGQPGSTAFLKCCSSFLPNDLGFIDTYSQKAFCGIYSKDGQIFMSACQDQVIRMYDCRYGRFHKFKSIKARDVGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPVERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADMSSQILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGMEASRQAATQQDWDYRWQQVPKKAWRKLKLPGDSSLMTYRGHGVLHTLIRCRFSPTYSTGQQYIYSGCSTGKVVVYDLLSGHIVKKLTSHKACVRDVSWHPFEEKIVSSSWDGNLRLWQYRQAEYFQDDMPESEEHPSSPASVSHPSTAFSSPQ", "length": 445, "header": "tr|A0A5G2RH85-1|A0A5G2RH85_PIG Computationally mapped isoform of DDB1- and CUL4-associated factor 11 OS=Sus scrofa OX=9823 GN=DCAF11 PE=3 SV=1 CANONICAL=A0A4X1SM17-1" }, "locus": { "chromosome": "7", "start_pos": 75179096, "end_pos": 75171936, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079370.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079370.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070676.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070676.1" } ] } }, { "isoform_ac": "A0A8D0IZ08-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17/entry#A0A8D0IZ08-1", "sequence": { "sequence": "MGSRNSSSAGTGSGDPSEGLPRRGAGLRRSEEEEEEDEDVDLAQVLAYLLRRGQVRLVQGGGAANLQLIQALSDSEEEHDNAWDGRLGDRYNPPVDATPDTRDLECSEIKTQVELATGRLGHRRAAREHSFPQMLLQRERGLCHRGSFSLGEQSRVMSHFLPNDLGFIDTYSQKAFCGIYSKDGQIFMSACQDQVIRMYDCRYGRFHKFKSIKARDVGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPVERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADMSSQILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGMEASRQAATQQDWDYRWQQVPKKVYDLLSGHIVKKLTSHKACVRDVSWHPFEEKIVSSSWDGNLRLWQYRQAEYFQDDMPESEEHPSSPASVSHPSTAFSSPQ", "length": 495, "header": "tr|A0A8D0IZ08-1|A0A4X1SM17_PIG Computationally mapped isoform of DDB1- and CUL4-associated factor 11 OS=Sus scrofa OX=9823 GN=DCAF11 PE=3 SV=1 CANONICAL=A0A4X1SM17-1" }, "locus": { "chromosome": "7", "start_pos": 75180222, "end_pos": 75171936, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102153.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102153.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078631.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078631.1" } ] } }, { "isoform_ac": "A0A8D1GPS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17/entry#A0A8D1GPS1-1", "sequence": { "sequence": "MGSRNSSSAGTGSGDPSEGLPRRGAGLRRSEEEEEEDEDVDLAQVLAYLLRRGQVRLVQGGGAANLQLIQALSDSEEEHDNAWDGRLGDRYNPPVDATPDTRDLECSEIKTQVELATGRLGHRRAAREHSFPQMLLQRERGLCHRGSFSLGEQSRVMSHFLPNDLGFIDTYSQKAFCGIYSKDGQIFMSACQDQVIRMYDCRYGRFHKFKSIKARDVGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPVERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADMSSQILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGMEASRQAATQQDWDYRWQQVPKKAWRKLKLPGDSSLMTYRGHGVLHTLIRCRFSPTYSTGQQYIYSGCSTGKVVVYDLLSGHIVKKLTSHKACVRDVSWHPLQPFPRPSRSDLQPYSWVSLLTSSPPPPPPFLPSGGFLRNHWHWMGRTRSPGFGPLPEPWEIIRLEENGLLTGSHPVGLGLCLWPGSGRTTTVSGVALSEGEPS", "length": 597, "header": "tr|A0A8D1GPS1-1|A0A4X1SM17_PIG Computationally mapped isoform of DDB1- and CUL4-associated factor 11 OS=Sus scrofa OX=9823 GN=DCAF11 PE=3 SV=1 CANONICAL=A0A4X1SM17-1" }, "locus": { "chromosome": "7", "start_pos": 75180222, "end_pos": 75171647, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002247.4", "url": "https://www.ensembl.org/id/ENSSSCT00000002247.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002195.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002195.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 98, "start_aa": "Thr", "end_pos": 98, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr98", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0IZ08", "url": "https://www.uniprot.org/uniprotkb/A0A8D0IZ08" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157270", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157270", "resource": "KEGG Pathway" }, { "id": "R-SSC-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MVT2-1", "protein_name": "DDB1- and CUL4-associated factor 11", "gene_name": "DCAF11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSRNSSSAGTGSGDPSEGLPRRGAGLRRSEEEEEEDEDVDLAQVLAYLLRRGQVRLVQGGGAANLQLIQALSDSEEEHDSAWDGRLGDRYNPPVDATPDTRELECSEIKTQVELATGRLGLRRAARELSFPQMLHQRERGLCHQGSFSLGERSRVMSHFLPNDLGFTDTYSQKAFCGIYSKDGQIFMSACQDQTIRLYDCRYGRFRKFKSIKARDVGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPDERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADVSSQILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGMEASRQAATQQNWDYRWQQVPKKAWRKLKLPGDSSLMTYRGHGVLHTLIRCRFSPTHSTGQQFIYSGCSTGKVVVYDLLSGHIVKKLTTHKACVRDVSWHPFEEKIVSSSWDGNLRLWQYRQAEYFQDDMPESEEHPSTPAPMSHPSTAFSSPQ", "length": 546 }, "evidence": [ { "id": "A0A4X1SM17", "url": "https://omabrowser.org/oma/group/A0A4X1SM17/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5M9G8-1", "protein_name": "DDB1- and CUL4-associated factor 11", "gene_name": "Dcaf11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSRNSSSAGSGSLEPSEGLSRRGAGLRRSEEEEEEDEDVDLAQVLAYLLRRGQVRLVQGGGAANLQLIQALSDSEEEHDSAWDGRLGDRYNPPVDATPDTRELEYNEIKTRVELATGRLGLGRTAQEHSFPRMLHQRERGLCHRGSFSLGEQSRVMSHFLPNDLSFTDTYSQKAFCGIYSKDGQIFMSACQDQTIRLYDCRYGRFHKFKSIKARDVGWSVLDVAFTPDGNHFLYSSWSDYIHICSIYGEGDTHTALDLRPDERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADISSQILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGMEASRLAATQQNWDYRWQQVPKKAWKKLKLPGDSSLMTYRGHGVLHTLIRCRFSPAHSTGQQFIYSGCSTGKVVVYDLLSGHIVKKLTNHKACVRDVSWHPFEEKIVSSSWDGSLRLWQYRQAEYFQDDMTESDRNRVCSSGPAPVPCPSVAFSSPQ", "length": 549 }, "evidence": [ { "id": "A0A4X1SM17", "url": "https://omabrowser.org/oma/group/A0A4X1SM17/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TEB1-1", "protein_name": "DDB1- and CUL4-associated factor 11", "gene_name": "DCAF11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSRNSSSAGSGSGDPSEGLPRRGAGLRRSEEEEEEDEDVDLAQVLAYLLRRGQVRLVQGGGAANLQFIQALLDSEEENDRAWDGRLGDRYNPPVDATPDTRELEFNEIKTQVELATGQLGLRRAAQKHSFPRMLHQRERGLCHRGSFSLGEQSRVISHFLPNDLGFTDSYSQKAFCGIYSKDGQIFMSACQDQTIRLYDCRYGRFRKFKSIKARDVGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPDERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADISSQILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGMEASRQAATQQNWDYRWQQVPKKAWRKLKLPGDSSLMTYRGHGVLHTLIRCRFSPIHSTGQQFIYSGCSTGKVVVYDLLSGHIVKKLTNHKACVRDVSWHPFEEKIVSSSWDGNLRLWQYRQAEYFQDDMPESEECASAPAPVPQSSTPFSSPQ", "length": 546 }, "evidence": [ { "id": "A0A4X1SM17", "url": "https://omabrowser.org/oma/group/A0A4X1SM17/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91VU6-1", "protein_name": "DDB1- and CUL4-associated factor 11", "gene_name": "Dcaf11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSRNSSSAGSGSLEPSEGLSRRGTGLRRSEEEEEEDEDVDLAQVLAYLLRRGQVRLVQGRGAANLQLIQALSDSEEEHDSAWDGRLGDRYNPPVDATPDTRELEYNEIKTQVGLATGRLGLRRTALQQSFPQMLHQRERGLCHRGSFSLGEQSRVMSHFLPNDLSFTDTYSQKAFCGIYSKDGQIFMSACQDQTIRLYDCRYGRFHKFKSIKARDVGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPDERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADISSQILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGMEASRLAATQQNWDYRWQQVPKIAWKKLKLPGDSSLMTYRGHGVLHTLIRCRFSPAHSTGQQFIYSGCSTGKVVVYDLLSGHIVKKLTNHKACVRDVSWHPFEEKIVSSSWDGNLRLWQYRQAEYFQDDMPESDMNRVCSSGPTPVPCPSVAFSSPQ", "length": 549 }, "evidence": [ { "id": "A0A4X1SM17", "url": "https://omabrowser.org/oma/group/A0A4X1SM17/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17" } ], "pmid": "" }, { "name": "Cul4-RING E3 ubiquitin ligase complex", "id": "GO:0080008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080008", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 98 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TN26-1", "uniprot_ac": "A0A4X1TN26", "uniprot_id": "A0A4X1TN26_PIG", "mass": { "chemical_mass": 68788.0, "monoisotopic_mass": 68788.0 }, "refseq": {}, "gene_names": [ { "name": "ARNTL", "type": "recommended", "evidence": [ { "id": "A0A4X1TN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ] }, { "name": "BMAL1", "type": "recommended", "evidence": [ { "id": "A0A4X1TN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ] }, { "name": "BMAL1", "type": "synonym", "evidence": [ { "id": "A0A4X1TN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ] } ], "protein_names": [ { "name": "Aryl hydrocarbon receptor nuclear translocator like", "type": "synonym", "evidence": [ { "id": "A0A4X1TN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BMAL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26", "locus": { "chromosome": "2", "start_pos": 45895289, "end_pos": 45988570, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013397", "url": "https://www.ensembl.org/id/ENSSSCG00000013397" } ] } } ], "crossref": [ { "id": "A0A4X1TN26", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TN26", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013397", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013397", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00130", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00130", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11438", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11438", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100037286", "url": "https://www.ncbi.nlm.nih.gov/gene/100037286", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PPTMVPD", "url": "https://omabrowser.org/oma/group/PPTMVPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23042", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23042", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9768919", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9768919", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B547", "url": "https://www.uniprot.org/uniprotkb/A0A287B547", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B547-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B547-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BKG6", "url": "https://www.uniprot.org/uniprotkb/A0A287BKG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BKG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BKG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TN26-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S978", "url": "https://www.uniprot.org/uniprotkb/F1S978", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S978-1", "url": "https://www.uniprot.org/uniprotkb/F1S978-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADQRMDISSTISDFMSPGATDLLSSPLGTSGVDCNRKRKGSSTDYQESMDTDKDDPHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFPSTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHMVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSSGLLPGQAQENPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 626, "header": "tr|A0A4X1TN26-1|A0A4X1TN26_PIG Isoform 1 of Aryl hydrocarbon receptor nuclear translocator like OS=Sus scrofa OX=9823 GN=BMAL1 PE=4 SV=1 CANONICAL=A0A4X1TN26-1" }, "isoforms": [ { "isoform_ac": "A0A287B547-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26/entry#A0A287B547-1", "sequence": { "sequence": "MADQRMDISSTISDFMSPGATDLLSSPLGTSGVDCNRKRKGSSTDYQLDGFSFEESMDTDKDDPHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFPSTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHMVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSSGLLPGQAQENPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 633, "header": "tr|A0A287B547-1|A0A4X1TN26_PIG Computationally mapped isoform of Aryl hydrocarbon receptor nuclear translocator like OS=Sus scrofa OX=9823 GN=BMAL1 PE=4 SV=1 CANONICAL=A0A4X1TN26-1" }, "locus": { "chromosome": "2", "start_pos": 45941530, "end_pos": 45896146, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052499.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052499.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051561.1", "url": "https://www.ensembl.org/id/ENSSSCP00000051561.1" } ] } }, { "isoform_ac": "A0A287BKG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26/entry#A0A287BKG6-1", "sequence": { "sequence": "MSNIESMDTDKDDPHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFPSTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHMVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSSGLLPGQAQENPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 582, "header": "tr|A0A287BKG6-1|A0A4X1TN26_PIG Computationally mapped isoform of Aryl hydrocarbon receptor nuclear translocator like OS=Sus scrofa OX=9823 GN=BMAL1 PE=4 SV=2 CANONICAL=A0A4X1TN26-1" }, "locus": { "chromosome": "2", "start_pos": 45940523, "end_pos": 45896146, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043425.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043425.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057088.3", "url": "https://www.ensembl.org/id/ENSSSCP00000057088.3" } ] } }, { "isoform_ac": "A0A4X1TN26-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26/entry#A0A4X1TN26-1", "sequence": { "sequence": "MADQRMDISSTISDFMSPGATDLLSSPLGTSGVDCNRKRKGSSTDYQESMDTDKDDPHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFPSTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHMVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSSGLLPGQAQENPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 626, "header": "tr|A0A4X1TN26-1|A0A4X1TN26_PIG Isoform 1 of Aryl hydrocarbon receptor nuclear translocator like OS=Sus scrofa OX=9823 GN=BMAL1 PE=4 SV=1 CANONICAL=A0A4X1TN26-1" }, "locus": { "chromosome": "2", "start_pos": 45941530, "end_pos": 45896146, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014635.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014635.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014240.5", "url": "https://www.ensembl.org/id/ENSSSCP00000014240.5" } ] } }, { "isoform_ac": "F1S978-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26/entry#F1S978-1", "sequence": { "sequence": "MADQRMDISSTISDFMSPGATDLLSSPLGTSGVDCNRKRKGSSTDYQLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFPSTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHMVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLINTLYCRLANMLGGSRRTSGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSSGLLPGQAQENPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 602, "header": "tr|F1S978-1|F1S978_PIG Computationally mapped isoform of Aryl hydrocarbon receptor nuclear translocator like OS=Sus scrofa OX=9823 GN=ARNTL PE=4 SV=5 CANONICAL=A0A4X1TN26-1" }, "locus": { "chromosome": "2", "start_pos": 45941530, "end_pos": 45896146, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014634.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014634.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014239.5", "url": "https://www.ensembl.org/id/ENSSSCP00000014239.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B547", "url": "https://www.uniprot.org/uniprotkb/A0A287B547" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9768919", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9768919", "resource": "Reactome", "description": "NPAS4 regulates expression of target genes" } ], "orthologs": [ { "uniprot_canonical_ac": "O00327-2", "protein_name": "Basic helix-loop-helix ARNT-like protein 1", "gene_name": "BMAL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADQRMDISSTISDFMSPGPTDLLSSSLGTSGVDCNRKRKGSSTDYQESMDTDKDDPHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFPSTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSSGLLSGQAQENPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 626 }, "evidence": [ { "id": "A0A4X1TN26", "url": "https://omabrowser.org/oma/group/A0A4X1TN26/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EPW1-1", "protein_name": "Basic helix-loop-helix ARNT-like protein 1", "gene_name": "Bmal1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQRMDISSTISDFMSPGPTDLLSGSLSTSGVDCNRKRKGSATDYQESMDTDKDDPHGRLEYAEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTSLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFASTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDSEPDNEGCNLSCLVAIGRLHSHMVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSAGLLPGQAQETPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 626 }, "evidence": [ { "id": "A0A4X1TN26", "url": "https://omabrowser.org/oma/group/A0A4X1TN26/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WTL8-1", "protein_name": "Basic helix-loop-helix ARNT-like protein 1", "gene_name": "Bmal1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADQRMDISSTISDFMSPGPTDLLSGSLGTSGVDCNRKRKGSATDYQLDDFAFEESMDTDKDDPHGRLEYAEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFASTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHMVPQPANGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTAPPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSTGLLPGQAQETPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 632 }, "evidence": [ { "id": "A0A4X1TN26", "url": "https://omabrowser.org/oma/group/A0A4X1TN26/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "aryl hydrocarbon receptor binding", "id": "GO:0017162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017162", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "aryl hydrocarbon receptor complex", "id": "GO:0034751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034751", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "response to redox state", "id": "GO:0051775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051775", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "positive regulation of circadian rhythm", "id": "GO:0042753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042753", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "regulation of hair cycle", "id": "GO:0042634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 125, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN26" }, { "id": "PS50112", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50112" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PAS", "eco_id": "ECO_0000259", "start_pos": 143, "end_pos": 208, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 523, "end_pos": 525 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SL89-1", "uniprot_ac": "A0A4X1SL89", "uniprot_id": "A0A4X1SL89_PIG", "mass": { "chemical_mass": 38629.0, "monoisotopic_mass": 38629.0 }, "refseq": {}, "gene_names": [ { "name": "HP", "type": "recommended", "evidence": [ { "id": "A0A4X1SL89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" } ] } ], "protein_names": [ { "name": "Haptoglobin", "type": "recommended", "evidence": [ { "id": "A0A4X1SL89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89#function" }, { "database": "UniProtKB", "id": "ARBA00025619", "url": "https://www.uniprot.org/uniprotkb/ARBA00025619#function" }, { "database": "UniProtKB", "id": "PIRNR001137", "url": "https://www.uniprot.org/uniprotkb/PIRNR001137#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HP", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89", "locus": {} } ], "crossref": [ { "id": "A0A4X1SL89", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SL89", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24255", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24255", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24255:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24255:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1SK09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SK09-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SL89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SL89-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRFALGAVVALLLCGQLFAAETGNEATDATDDSCPKPPEIPKGYVEHMVRYHCQTYYKLRTAGDGVYTLDSNKQWTNKVTGEKLPECEAVCGKPKNPVDQVQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAKNLRLGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHPDNSTVDIGLIKLKQKVPVNERVMPICLPSKDYVNVGLVGYVSGWGRNANLNFTEHLKYVMLPVADQEKCVQYYEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKSCRTAEYGVYVRVTSILDWIQTTIADN", "length": 348, "header": "tr|A0A4X1SL89-1|A0A4X1SL89_PIG Isoform 1 of Haptoglobin OS=Sus scrofa OX=9823 GN=HP PE=3 SV=1 CANONICAL=A0A4X1SL89-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SK09-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89/entry#A0A4X1SK09-1", "sequence": { "sequence": "MRALGAVVALLLCGQLFAAETGNEATDATDDSCPKPPEIPKGYVEHMVRYHCQTYYKLRTAGDVCGKPKNPVDQVQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAKNLRLGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHPDNSTVDIGLIKLKQKVPVNERVMPICLPSKDYVNVGLVGYVSGWGRNANLNFTEHLKYVMLPVADQEKCVQYYEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKSCRTAEYGVYVRVTSILDWIQTTIADN", "length": 322, "header": "tr|A0A4X1SK09-1|A0A4X1SK09_PIG Computationally mapped isoform of Haptoglobin OS=Sus scrofa OX=9823 GN=HP PE=4 SV=1 CANONICAL=A0A4X1SL89-1" }, "locus": { "chromosome": "6", "start_pos": 14985095, "end_pos": 14980531, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003046.4", "url": "https://www.ensembl.org/id/ENSSSCT00000003046.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002967.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002967.3" } ] } }, { "isoform_ac": "A0A4X1SL89-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89/entry#A0A4X1SL89-1", "sequence": { "sequence": "MRFALGAVVALLLCGQLFAAETGNEATDATDDSCPKPPEIPKGYVEHMVRYHCQTYYKLRTAGDGVYTLDSNKQWTNKVTGEKLPECEAVCGKPKNPVDQVQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAKNLRLGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHPDNSTVDIGLIKLKQKVPVNERVMPICLPSKDYVNVGLVGYVSGWGRNANLNFTEHLKYVMLPVADQEKCVQYYEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKSCRTAEYGVYVRVTSILDWIQTTIADN", "length": 348, "header": "tr|A0A4X1SL89-1|A0A4X1SL89_PIG Isoform 1 of Haptoglobin OS=Sus scrofa OX=9823 GN=HP PE=3 SV=1 CANONICAL=A0A4X1SL89-1" }, "locus": { "chromosome": "6", "start_pos": 14985095, "end_pos": 14981024, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104823.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104823.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074830.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074830.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" } ], "pmid": "" }, { "name": "hemoglobin binding", "id": "GO:0030492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030492", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" } ], "pmid": "" }, { "name": "antioxidant activity", "id": "GO:0016209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016209", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" } ], "pmid": "" }, { "name": "acute-phase response", "id": "GO:0006953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006953", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SL89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 104, "end_pos": 346, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SL89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL89" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 89, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 233, "end_pos": 235 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T413-1", "uniprot_ac": "A0A4X1T413", "uniprot_id": "A0A4X1T413_PIG", "mass": { "chemical_mass": 40328.0, "monoisotopic_mass": 40328.0 }, "refseq": {}, "gene_names": [ { "name": "HOMER1", "type": "recommended", "evidence": [ { "id": "A0A4X1T413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ] } ], "protein_names": [ { "name": "Homer protein homolog 1", "type": "recommended", "evidence": [ { "id": "A0A4X1T413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HOMER1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413", "locus": { "chromosome": "2", "start_pos": 88122882, "end_pos": 88255281, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014113", "url": "https://www.ensembl.org/id/ENSSSCG00000014113" } ] } } ], "crossref": [ { "id": "A0A4X1T413", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T413", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014113", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014113", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01206", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01206", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10918", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10918", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00568", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00568", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6794361", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6794361", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZL34", "url": "https://www.uniprot.org/uniprotkb/A0A286ZL34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZL34-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZL34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T413-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T4A0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T4A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4A0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIH9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R052", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R052", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R052-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R052-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFU4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1CEY2", "url": "https://www.uniprot.org/uniprotkb/A0A8D1CEY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1CEY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1CEY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RF45", "url": "https://www.uniprot.org/uniprotkb/F1RF45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RF45-1", "url": "https://www.uniprot.org/uniprotkb/F1RF45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRPEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHSHKTELNQTIQELEETLKVKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLERS", "length": 354, "header": "tr|A0A4X1T413-1|A0A4X1T413_PIG Isoform 1 of Homer protein homolog 1 OS=Sus scrofa OX=9823 GN=HOMER1 PE=1 SV=1 CANONICAL=A0A4X1T413-1" }, "isoforms": [ { "isoform_ac": "A0A286ZL34-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413/entry#A0A286ZL34-1", "sequence": { "sequence": "REQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRPEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHSHKTELNQTIQELEETLKVKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLERS", "length": 322, "header": "tr|A0A286ZL34-1|A0A4X1T413_PIG Computationally mapped isoform of Homer protein homolog 1 OS=Sus scrofa OX=9823 GN=HOMER1 PE=1 SV=2 CANONICAL=A0A4X1T413-1" }, "locus": { "chromosome": "2", "start_pos": 88206329, "end_pos": 88125811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058872.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058872.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032317.2", "url": "https://www.ensembl.org/id/ENSSSCP00000032317.2" } ] } }, { "isoform_ac": "A0A4X1T413-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413/entry#A0A4X1T413-1", "sequence": { "sequence": "MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRPEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHSHKTELNQTIQELEETLKVKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLERS", "length": 354, "header": "tr|A0A4X1T413-1|A0A4X1T413_PIG Isoform 1 of Homer protein homolog 1 OS=Sus scrofa OX=9823 GN=HOMER1 PE=1 SV=1 CANONICAL=A0A4X1T413-1" }, "locus": { "chromosome": "2", "start_pos": 88253477, "end_pos": 88125811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057415.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057415.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043946.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043946.1" } ] } }, { "isoform_ac": "A0A4X1T4A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413/entry#A0A4X1T4A0-1", "sequence": { "sequence": "MAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRPEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHSHKTELNQTIQELEETLKVKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLERS", "length": 345, "header": "tr|A0A4X1T4A0-1|A0A4X1T4A0_PIG Computationally mapped isoform of Homer protein homolog 1 OS=Sus scrofa OX=9823 GN=HOMER1 PE=1 SV=1 CANONICAL=A0A4X1T413-1" }, "locus": { "chromosome": "2", "start_pos": 88207188, "end_pos": 88125811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062712.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062712.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037935.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037935.2" } ] } }, { "isoform_ac": "A0A5G2QIH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413/entry#A0A5G2QIH9-1", "sequence": { "sequence": "MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKVTELECVSSQANAVHSHKTELNQTIQELEETLKVKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLERS", "length": 224, "header": "tr|A0A5G2QIH9-1|A0A5G2QIH9_PIG Computationally mapped isoform of Homer protein homolog 1 OS=Sus scrofa OX=9823 GN=HOMER1 PE=1 SV=2 CANONICAL=A0A4X1T413-1" }, "locus": { "chromosome": "2", "start_pos": 88253477, "end_pos": 88125811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082169.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082169.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063706.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063706.2" } ] } }, { "isoform_ac": "A0A5G2R052-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413/entry#A0A5G2R052-1", "sequence": { "sequence": "MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRPEPTQNALPFSHRK", "length": 177, "header": "tr|A0A5G2R052-1|A0A4X1T413_PIG Computationally mapped isoform of Homer protein homolog 1 OS=Sus scrofa OX=9823 GN=HOMER1 PE=1 SV=2 CANONICAL=A0A4X1T413-1" }, "locus": { "chromosome": "2", "start_pos": 88253477, "end_pos": 88125993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066867.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066867.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070497.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070497.2" } ] } }, { "isoform_ac": "A0A5G2RFU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413/entry#A0A5G2RFU4-1", "sequence": { "sequence": "AHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRPEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHSHKTELNQTIQELEETLKVKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLERS", "length": 344, "header": "tr|A0A5G2RFU4-1|A0A4X1T413_PIG Computationally mapped isoform of Homer protein homolog 1 OS=Sus scrofa OX=9823 GN=HOMER1 PE=1 SV=2 CANONICAL=A0A4X1T413-1" }, "locus": { "chromosome": "2", "start_pos": 88206302, "end_pos": 88125811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073857.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073857.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069959.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069959.2" } ] } }, { "isoform_ac": "A0A8D1CEY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413/entry#A0A8D1CEY2-1", "sequence": { "sequence": "ITDFLHLGTDSAQEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRPEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHSHKTELNQTIQELEETLKVKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLERS", "length": 365, "header": "tr|A0A8D1CEY2-1|A0A4X1T413_PIG Computationally mapped isoform of Homer protein homolog 1 OS=Sus scrofa OX=9823 GN=HOMER1 PE=1 SV=1 CANONICAL=A0A4X1T413-1" }, "locus": { "chromosome": "2", "start_pos": 88206838, "end_pos": 88125811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056443.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056443.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033817.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033817.2" } ] } }, { "isoform_ac": "A0A8W4FGZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413/entry#A0A8W4FGZ9-1", "sequence": { "sequence": "MGSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHSHKTELNQTIQELEETLKVKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLERS", "length": 180, "header": "tr|A0A8W4FGZ9-1|A0A4X1T413_PIG Computationally mapped isoform of Homer protein homolog 1 OS=Sus scrofa OX=9823 GN=HOMER1 PE=1 SV=1 CANONICAL=A0A4X1T413-1" }, "locus": { "chromosome": "2", "start_pos": 88253477, "end_pos": 88125811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100100.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100100.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078511.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078511.1" } ] } }, { "isoform_ac": "F1RF45-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413/entry#F1RF45-1", "sequence": { "sequence": "ITRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRPEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHSHKTELNQTIQELEETLKVKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLERS", "length": 347, "header": "tr|F1RF45-1|A0A4X1T413_PIG Computationally mapped isoform of Homer protein homolog 1 OS=Sus scrofa OX=9823 GN=HOMER1 PE=1 SV=5 CANONICAL=A0A4X1T413-1" }, "locus": { "chromosome": "2", "start_pos": 88206578, "end_pos": 88125811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015416.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015416.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015007.5", "url": "https://www.ensembl.org/id/ENSSSCP00000015007.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZL34", "url": "https://www.uniprot.org/uniprotkb/A0A286ZL34" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6794361", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6794361", "resource": "Reactome", "description": "Neurexins and neuroligins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled glutamate receptor binding", "id": "GO:0035256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035256", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "costamere", "id": "GO:0043034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043034", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "postsynaptic cytosol", "id": "GO:0099524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "G protein-coupled glutamate receptor signaling pathway", "id": "GO:0007216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007216", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "regulation of calcium ion import", "id": "GO:0090279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090279", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "response to calcium ion", "id": "GO:0051592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051592", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "regulation of synaptic transmission, glutamatergic", "id": "GO:0051966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051966", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" }, { "name": "regulation of store-operated calcium entry", "id": "GO:2001256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001256", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T413", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T413" }, { "id": "PS50229", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50229" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WH1", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 110, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 250, "end_pos": 252 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T1S2-1", "uniprot_ac": "A0A4X1T1S2", "uniprot_id": "A0A4X1T1S2_PIG", "mass": { "chemical_mass": 138217.0, "monoisotopic_mass": 138217.0 }, "refseq": {}, "gene_names": [ { "name": "SIK3", "type": "recommended", "evidence": [ { "id": "A0A4X1T1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A4X1T1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A4X1T1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SIK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2", "locus": { "chromosome": "9", "start_pos": 44223232, "end_pos": 44513831, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015071", "url": "https://www.ensembl.org/id/ENSSSCG00000015071" } ] } } ], "crossref": [ { "id": "A0A4X1T1S2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T1S2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015071", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015071", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14410", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14410", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HRYIYKD", "url": "https://omabrowser.org/oma/group/HRYIYKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23312", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23312", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AA34", "url": "https://www.uniprot.org/uniprotkb/A0A287AA34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AA34-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AA34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1Z5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAI1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FH82", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FH82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FH82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FH82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FPB9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FPB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQH7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJT2", "url": "https://www.uniprot.org/uniprotkb/F1SJT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJT2-1", "url": "https://www.uniprot.org/uniprotkb/F1SJT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSSYNIKVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPSMPRAMAFQAPVNIQAEQAGTTMNISVPQVQLINPENQIVEPDGTVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNMNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQPFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMNSAMIQSHGAASPSQFQGFPSRSAVFQQQPENCSPPPNVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGTAAGSAGRGVSVSPSASQVQMQHRTNLIAAFSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPPTGVGFPPTQALKVPPLDQFPTFPPSAHPQSPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQQRQQQQQQQQEYQELLRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHHTSPQHLLQIRAQECISQASSASPTHAYAQQPALVHSESMEEECSCDGAKDGFPDRKSASTLAKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGLHPYRQAAAAFPRNKVSSRESVIGNCMDRSSPGQAMELPDHNGLGYPAHPSVSEHHRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGEHLGAHEHADLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1247, "header": "tr|A0A4X1T1S2-1|A0A4X1T1S2_PIG Isoform 1 of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SIK3 PE=1 SV=1 CANONICAL=A0A4X1T1S2-1" }, "isoforms": [ { "isoform_ac": "A0A287AA34-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2/entry#A0A287AA34-1", "sequence": { "sequence": "MKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPSMPRAMAFQAPVNIQAEQAGTTMNISVPQVQLINPENQIVEPDGTVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNMNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQPFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMNSAMIQSHGAASPSQFQGFPSRSAVFQQQPENCSPPPNVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGTAAGSAGRGVSVSPSASQVQMQHRTNLIAAFSYGHRPLSKQLSADSAEAHSAHPQSPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQQRQQQQQQQQEYQELLRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHHTSPQHLLQIRAQECISQASSASPTHAYAQQPALVHSESMEEECSCDGAKDGFPDRKSASTLAKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGLHPYRQAAAAFPRNKVSSRESVIGNCMDRSSPGQAMELPDHNGLGYPAHPSVSEHHRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGEHLGAHEHADLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1192, "header": "tr|A0A287AA34-1|A0A4X1T1S2_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SIK3 PE=1 SV=1 CANONICAL=A0A4X1T1S2-1" }, "locus": { "chromosome": "9", "start_pos": 44331947, "end_pos": 44226357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049401.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049401.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040794.1", "url": "https://www.ensembl.org/id/ENSSSCP00000040794.1" } ] } }, { "isoform_ac": "A0A4X1T1S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2/entry#A0A4X1T1S2-1", "sequence": { "sequence": "MAVSSYNIKVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPSMPRAMAFQAPVNIQAEQAGTTMNISVPQVQLINPENQIVEPDGTVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNMNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQPFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMNSAMIQSHGAASPSQFQGFPSRSAVFQQQPENCSPPPNVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGTAAGSAGRGVSVSPSASQVQMQHRTNLIAAFSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPPTGVGFPPTQALKVPPLDQFPTFPPSAHPQSPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQQRQQQQQQQQEYQELLRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHHTSPQHLLQIRAQECISQASSASPTHAYAQQPALVHSESMEEECSCDGAKDGFPDRKSASTLAKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGLHPYRQAAAAFPRNKVSSRESVIGNCMDRSSPGQAMELPDHNGLGYPAHPSVSEHHRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGEHLGAHEHADLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1247, "header": "tr|A0A4X1T1S2-1|A0A4X1T1S2_PIG Isoform 1 of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SIK3 PE=1 SV=1 CANONICAL=A0A4X1T1S2-1" }, "locus": { "chromosome": "9", "start_pos": 44330101, "end_pos": 44226357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044866.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044866.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034865.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034865.1" } ] } }, { "isoform_ac": "A0A4X1T1Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2/entry#A0A4X1T1Z5-1", "sequence": { "sequence": "MKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPSMPRAMAFQAPVNIQAEQAGTTMNISVPQVQLINPENQIVEPDGTVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNMNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQSSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMNSAMIQSHGAASPSQFQGFPSRSAVFQQQPENCSPPPNVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGTAAGSAGRGVSVSPSASQVQMQHRTNLIAAFSYGHRPLSKQLSADSAEAHSAHPQSPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQQRQQQQQQQQEYQELLRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHHTSPQHLLQIRAQECISQASSASPTHAYAQQPALVHSESMEEECSCDGAKDGFPDRKSASTLAKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGLHPYRQAAAAFPRNKVSSRESVIGNCMDRSSPGQAMELPDHNGLGYPAHPSVSEHHRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGEHLGAHEHADLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1144, "header": "tr|A0A4X1T1Z5-1|A0A4X1T1Z5_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SIK3 PE=1 SV=1 CANONICAL=A0A4X1T1S2-1" }, "locus": { "chromosome": "9", "start_pos": 44331947, "end_pos": 44226357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025641.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025641.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027043.2", "url": "https://www.ensembl.org/id/ENSSSCP00000027043.2" } ] } }, { "isoform_ac": "A0A5G2RAI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2/entry#A0A5G2RAI1-1", "sequence": { "sequence": "MEFILNRVWVLSTNEFLQMQIRTVCCFPFICFTSLTHSHSEHPSFQLLLKLYHCPKRELTVFFFTADHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPSMPRAMAFQAPVNIQAEQAGTTMNISVPQVQLINPENQIVEPDGTVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNMNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQPFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMNSAMIQSHGAASPSQFQGFPSRSAVFQQQPENCSPPPNVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGTAAGSAGRGVSVSPSASQVQMQHRTNLIAAFSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPPTGVGFPPTQALKVPPLDQFPTFPPSAHPQSPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQQRQQQQQQQQEYQELLRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHHTSPQHLLQIRAQECISQASSASPTHAYAQQPALVHSESMEEECSCDGAKDGFPDRKSASTLAKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGLHPYRQAAAAFPRNKVSSRESVIGNCMDRSSPGQAMELPDHNGLGYPAHPSVSEHHRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGEHLGAHEHADLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1283, "header": "tr|A0A5G2RAI1-1|A0A4X1T1S2_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SIK3 PE=1 SV=1 CANONICAL=A0A4X1T1S2-1" }, "locus": { "chromosome": "9", "start_pos": 44299515, "end_pos": 44226357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088508.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088508.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071135.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071135.1" } ] } }, { "isoform_ac": "A0A8W4FH82-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2/entry#A0A8W4FH82-1", "sequence": { "sequence": "MAAAAASGAGGAAGAGAGGAGPAGRLLPPPAPGPPAAPAAVPPAAGPPRPPAPASRGPVPARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEELKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMEDMGLDKERTLQAEQAGTTMNISVPQVQLINPENQIVEPDGTVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNMNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQPFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMNSAMIQSHGAASPSQFQGFPSRSAVFQQQPENCSPPPNVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGTAAGSAGRGVSVSPSASQVQMQHRTNLIAAFSYGHRPLSKQLSADSAEAHSAHPQSPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQQRQQQQQQQQEYQELLRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHHTSPQHLLQIRAQECISQASSASPTHAYAQQPALVHSESMEEECSCDGAKDGFPDRKSASTLAKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGLHPYRQAAAAFPRNKVSSRESVIGNCMDRSSPGQAMELPDHNGLGYPAHPSVSEHHRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGEHLGAHEHADLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1259, "header": "tr|A0A8W4FH82-1|A0A4X1T1S2_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SIK3 PE=1 SV=1 CANONICAL=A0A4X1T1S2-1" }, "locus": { "chromosome": "9", "start_pos": 44471689, "end_pos": 44226357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093584.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093584.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078236.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078236.1" } ] } }, { "isoform_ac": "A0A8W4FPB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2/entry#A0A8W4FPB9-1", "sequence": { "sequence": "MKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPSMPRAMAFQAPVNIQAEQAGTTMNISVPQVQLINPENQIVEPDGTVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNMNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQPFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMNSAMIQSHGAASPSQFQGFPSRSAVFQQQPENCSPPPNVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGTAAGSAGRGVSVSPSASQVQMQHRTNLIAAFSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPPTGVGFPPTQALKVPPLDQFPTFPPSAHPQSPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQQRQQQQQQQQEYQELLRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHHTSPQHLLQIRAQECISQASSASPTHAYAQQPALVHSESMEEECSCDGAKDGFPDRKSASTLAKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGLHPYRQAAAAFPRNKVSSRESVIGNCMDRSSPGQAMELPDHNGLGYPAHPSVSEHHRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGEHLGAHEHADLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1252, "header": "tr|A0A8W4FPB9-1|A0A4X1T1S2_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SIK3 PE=1 SV=1 CANONICAL=A0A4X1T1S2-1" }, "locus": { "chromosome": "9", "start_pos": 44331947, "end_pos": 44226357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098901.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098901.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081033.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081033.1" } ] } }, { "isoform_ac": "A0A8W4FQH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2/entry#A0A8W4FQH7-1", "sequence": { "sequence": "MAAAAASGAGGAAGAGAGGAGPAGRLLPPPAPGPPAAPAAVPPAAGPPRPPAPASRGPVPARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEELKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPSMPRAMAFQAPVNIQAEQAGTTMNISVPQVQLINPENQIVEPDGTVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNMNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQPFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMNSAMIQSHGAASPSQFQGFPSRSAVFQQQPENCSPPPNVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGTAAGSAGRGVSVSPSASQVQMQHRTNLIAAFSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPPTGVGFPPTQALKVPPLDQFPTFPPSAHPQSPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQQRQQQQQQQQEYQELLRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHHTSPQHLLQIRAQECISQASSASPTHAYAQQPALVHSESMEEECSCDGAKDGFPDRKSASTLAKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGLHPYRQAAAAFPRNKVSSRESVIGNCMDRSSPGQAMELPDHNGLGYPAHPSVSEHHRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGEHLGAHEHADLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1367, "header": "tr|A0A8W4FQH7-1|A0A4X1T1S2_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SIK3 PE=1 SV=1 CANONICAL=A0A4X1T1S2-1" }, "locus": { "chromosome": "9", "start_pos": 44471689, "end_pos": 44226357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101550.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101550.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081270.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081270.1" } ] } }, { "isoform_ac": "F1SJT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2/entry#F1SJT2-1", "sequence": { "sequence": "GTLLCIPENMFFFTADHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPSMPRAMAFQAPVNIQAEQAGTTMNISVPQVQLINPENQIVEPDGTVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNMNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQPFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMNSAMIQSHGAASPSQFQGFPSRSAVFQQQPENCSPPPNVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGTAAGSAGRGVSVSPSASQVQMQHRTNLIAAFSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPPTGVGFPPTQALKVPPLDQFPTFPPSAHPQSPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQQRQQQQQQQQEYQELLRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHHTSPQHLLQIRAQECISQASSASPTHAYAQQPALVHSESMEEECSCDGAKDGFPDRKSASTLAKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGLHPYRQAAAAFPRNKVSSRESVIGNCMDRSSPGQAMELPDHNGLGYPAHPSVSEHHRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGEHLGAHEHADLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1232, "header": "tr|F1SJT2-1|F1SJT2_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SIK3 PE=1 SV=4 CANONICAL=A0A4X1T1S2-1" }, "locus": { "chromosome": "9", "start_pos": 44299919, "end_pos": 44226357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016437.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016437.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015995.4", "url": "https://www.ensembl.org/id/ENSSSCP00000015995.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 464, "start_aa": "Thr", "end_pos": 464, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr464", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 882, "start_aa": "Thr", "end_pos": 882, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr882", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FH82", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FH82" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A0T3-1", "protein_name": "Serine/threonine-protein kinase SIK3", "gene_name": "Sik3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAASGAGGVAVAGAGGAGPAGRLLPPPAAGPPAAPAAVPPAACPPRPTAPASRGSMAARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHRWMKLGDADPNFERLIAECQQLKEERQAEPLNDEVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKKNKTLRPGALPSTPQAMTFQAPVNIQAEQTGTAMNISVPQVQLINPENQIIEPDGAVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMDEMQKLLPGFPGANPQTPFLQVAPNMNFMHNLLPMQSLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQSSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLERMGNSSSIKQLQQECEQLQKMYGGQVDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPTLLTHQLQRLRIQPSSPPPNHPSNHLFRQPSNSPPPVSSAMISSHGATSPSQFQGLPSHGAIFQQQPENCSPPPSVALTCLGLQQASQSQPVTIQLQEPVDMLSNMAGTTAGSAGRGIPISPSASQIQMQHRTSLMAPFGYGHRPLSKQLSADSAEAHSLSMNRFSPANYDQAHLHPHLFSEQSRGPPSSYSPSTGVGFPPAQALRVPPLDQFPTFPPSAHQQPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQHRQQQQQQQQQQQQEYHELFRHMNQGDAVSLAPGLGGQNMTEHQALSYQNADSYHRHHTSPQHLLQIRAQDCISQGPLPTPTRGYARQSPLMHSESMEEDCLCEGVKEGFADKSSSTLTKGCHDSPLLLCTSGPGDPEPLLGTVSQARELGIHPYGHQPTATTFSRNKVPSRESVIGNCMERSSPGQAMELPDHNGLGYPARPLVSEHLRSRTLQRHHTIQNSDDAYVQLDTLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDEEDEECGVSLGHEHPALGDGSQHLNSRYPATCVTDIMLNHKHPEVSFSMEQAGV", "length": 1321 }, "evidence": [ { "id": "A0A4X1T1S2", "url": "https://omabrowser.org/oma/group/A0A4X1T1S2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1A7E9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "SIK3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAAAAAAASGAGGPPPAPRLPPAPPPPRPPGPARIGYYEIERTIGKGNFAVVKLATHLVTRAKVAIKIIDKTQLDDENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVNFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNIFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPSKRLSMDQICKHKWMKLGEADAEFDRLIAECQHLKTERQMEPLNEDVLLAMAEMGLDKERTIQSLRADAYDHYSAIYSLLCDRLKRHKNLRIAPSPSIPRTVTFPTSANIQQTEQAGNTMNINVPQVQLINPENQIVETDGTMNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPRVTPQAPFLQVTPNVNFMHNVLPRQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTNPTAEIPPDLQRQLGQQSFRPRAWAPHLVPDQHRSIYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGHMDERTLEKTQQQHMLYQQEQHHQILHQQIQDCIRPPQPSPPLQAQCENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPNSSPPPVSSSVLQPHGAASQSQFQGMPSHNTIFPQSGNCSPPPTMGLTCLALQQQSQAQQVTIQVQEPGDMVSNNLLQGASVAGQGMSSHTRGMSISPSANQIQMQHRANLMASLTYGHRQLSKQLSADSAESHSLNVYRNPPANYDQVHLHPHLFPEQPRVSPSNYSPSGGVGFPPAQQALKVPQLDQYPNFPQNAHQQQQHYTASALQQALLSPTPPDYSRHQQVPHILQGLLSPRHSLTGHTDMRLPQAEFAQLIKRRQQQQQQQQQQQEFQELFRHMSQGDAGNMGTSMGQSLSERQSLSLPYQSADTYHPQNSPQHLLKIRAQECIQQVPASVPPHGYVHQPALFHSESMEEDCACEGARDSFPDSKNSNTLTKGCHETPLLVNAGGHGDPESLLGTANHVQELGTHQYRHQPAAGFSRNKVPSRESVVGNCMDRSSPGQAMQVPDHNGLGYPARPASSEHPRPRTLQRHHTIQNSDDAYVQLDNLPGMSLMAGKALSSARMSDAVLSQSSLMASQQLRDRESDECGESLEGQEHPNLGDGNQHLNTSCYPSTCITDVLLSYKHPEVPFGMEQAGV", "length": 1349 }, "evidence": [ { "id": "A0A4X1T1S2", "url": "https://omabrowser.org/oma/group/A0A4X1T1S2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6P4S6-1", "protein_name": "Serine/threonine-protein kinase SIK3", "gene_name": "Sik3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAASGAGGVAVAGAGGAGPAGRLLPPPAAGPPAAPAAVPPAAVPARPTAPASRGSMAARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKSQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHKWMKLGDADPNFDRLIAECQQLKEERQSDPLNDDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKKHKTLRPGALPSMPQAMTFQAPVNLQAEQTGTAMNLSVPQVQLINPENQIIEPDGAVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQGPFLQVAPNMNFTHNLLPMQSLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTSPTAEIPPDLQRQLGQQSFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNSSSIKQLQQECEQLQKMYGGQVDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQVACENQPALLTHQLQRLRIQPSSPPPNHPSNHLFRQPSNSPPPVSSAMITSHGATSPSQFQGLPSHGAIFQQQPENCSPPPSVALTCLGLQQASQSQPVTIQLQEPVDMLSNMAGTAAGSAGRSIPISPSASQIQIQHRASLMAPFSYGHRPLSKQLSADSAEAHSLNMNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPSTGVGFPPTQALKVPPLDQFPTFPPSAQQQPPHYTTSALQQALLSPTPPDYPRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQHRQQQQQQQQQQEYHELFRHMNQGDAVSLAPSLGGQNMTEQQALSYQNADSYHRHHTSPQHILQIRAQDCISQGPSPTPTHGYAHQPPLMHSESMEEDCLCEGLKEGFPDKSSSTLTKGCHNSPLLLCTSGPGDPEPLLGTVSQARELGIHPYGHQPTATTFSRNKVPSRESVLGNCLERSSPGQAMELPDHNGLGYPVRPLVSEHLRSRTLQRHHTIQNSDDAYVQLDTLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDEEDEECGVSLGHEHPGLGDGSQHLNSSRYPATCVTDIMLSHKHPEVSFSMEQAGV", "length": 1369 }, "evidence": [ { "id": "A0A4X1T1S2", "url": "https://omabrowser.org/oma/group/A0A4X1T1S2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2K2-5", "protein_name": "Serine/threonine-protein kinase SIK3", "gene_name": "SIK3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAASGAGGAAGAGTGGAGPAGRLLPPPAPGSPAAPAAVSPAAGQPRPPAPASRGPMPARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQVDPLNEDVLLAMEDMGLDKEQTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRLGALPSMPRALAFQAPVNIQAEQAGTAMNISVPQVQLINPENQIVEPDGTLNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNVNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQSSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMSSAMIQPHGAASSSQFQGLPSRSAIFQQQPENCSSPPNVALTCLGMQQPAQSQQVTIQVQEPVDMLSNMPGTAAGSSGRGISISPSAGQMQMQHRTNLMATLSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPSTGVGFSPTQALKVPPLDQFPTFPPSAHQQPPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPTEFAQLIKRQQQQRQQQQQQQQQQEYQELFRHMNQGDAGSLAPSLGGQSMTERQALSYQNADSYHHHTSPQHLLQIRAQECVSQASSPTPPHGYAHQPALMHSESMEEDCSCEGAKDGFQDSKSSSTLTKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGIHPYGHQPTAAFSKNKVPSREPVIGNCMDRSSPGQAVELPDHNGLGYPARPSVHEHHRPRALQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGASLGGHEHPDLSDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1321 }, "evidence": [ { "id": "A0A4X1T1S2", "url": "https://omabrowser.org/oma/group/A0A4X1T1S2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "V6F977-1", "protein_name": "Serine/threonine-protein kinase SIK3", "gene_name": "SIK3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAAASGAGGAAGAGAGGAGPAGRLLPPPAPGPPAAPAAVPPAAGPPRPPAPASRGPVPARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVAAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQMDPLNEDVLLAMENMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKRHKTLRVGVPPGMPRTMGFQPPVNLQAEQAGTTMNISVPQVQLINPENQIVEPDGAVNVDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQAPFLQVAPNVNFMHNLLPMQNLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQSSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNNSSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQAACENQPALLTHQLQRLRIQPSSPPPNHPNNHLFRQPSNSPPPMSSAMMQSHGATSSSQFQGFPSRSAIFQQQPENCSPPPSVALTCLGIQQPPQSQQVTIQVQEPVDMLSSMPGAAAASAGRGVSISPNTSQVQMQLRTSLMAALSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPHLFSDQSRGSPSSYNPSSGAGLPPTQALKVPPLDQFPTFPPSAHQQPPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDMRLPPAEFAQLIKRRQRQQQQQEYQELFRHMNQGDAGSLAPGLGGQSMTERQALPYQNADSYHHHHTSPQHLLQIRAQECISQVSSPTPTHSYAPQAALVHSESMEEECSCEGAKDGFPDRKSGNTLTKGCHDSPLLLSTGGPGDPESLLGTVNHAQELGIHPYRQPAAAFTRNKVSSRESVLGKCMDRSSPGQAMELPDHNGLGYPAHPSVSEHQRPRTLQRHHTIQNSDDAYVQLDNLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDGENEECGESLGGQEHPDLTDGSQHLNSSCYPSTCITDILLSYKHPEVSFSMEQAGV", "length": 1314 }, "evidence": [ { "id": "A0A4X1T1S2", "url": "https://omabrowser.org/oma/group/A0A4X1T1S2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1217, "end_pos": 1219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 196, "start_aa": "Met", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1S2" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 223, "end_pos": 263, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 464, 882 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1217, "end_pos": 1219 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 711, "end_pos": 713 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SQF0-1", "uniprot_ac": "A0A4X1SQF0", "uniprot_id": "A0A4X1SQF0_PIG", "mass": { "chemical_mass": 91104.0, "monoisotopic_mass": 91104.0 }, "refseq": { "ac": "XP_020931971", "name": "dnaJ homolog subfamily C member 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931971" }, "gene_names": [ { "name": "DNAJC10", "type": "recommended", "evidence": [ { "id": "A0A4X1SQF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ] }, { "name": "DNAJC10", "type": "synonym", "evidence": [ { "id": "XP_020931971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931971" } ] } ], "protein_names": [ { "name": "DnaJ homolog subfamily C member 10", "type": "recommended", "evidence": [ { "id": "A0A4X1SQF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0/entry#names_and_taxonomy" } ] }, { "name": "1.8.4.-", "type": "synonym", "evidence": [ { "id": "A0A4X1SQF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0/entry#names_and_taxonomy" } ] }, { "name": "dnaJ homolog subfamily C member 10", "type": "synonym", "evidence": [ { "id": "XP_020931971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931971" } ] } ], "function": [ { "annotation": "Endoplasmic reticulum disulfide reductase that collaborates directly with a BIP/HSPA5 (GRP78)-type chaperone to maintain protein quality control by facilitating either the correct folding or the targeted degradation of misfolded proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0#function" }, { "database": "UniProtKB", "id": "PIRNR037293", "url": "https://www.uniprot.org/uniprotkb/PIRNR037293#function" } ] }, { "annotation": "Endoplasmic reticulum disulfide reductase that collaborates directly with the chaperone BIP/HSPA5 (GRP78) to maintain protein quality control by facilitating either the correct folding or the targeted degradation of misfolded proteins. Essential for efficient maturation of newly synthesized polypeptides in the endoplasmic reticulum, binds to substrate proteins and specifically catalyzes the reduction and removal of improper (non-native) disulfide bonds during the folding process. In endoplasmic reticulum-associated degradation (ERAD), DNAJC10 reduces incorrect disulfide bonds specifically in misfolded glycoproteins that have been recognized by EDEM1, a key component of the ERAD pathway, thereby enabling their retrotranslocation and degradation. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0#function" }, { "database": "UniProtKB", "id": "ARBA00094198", "url": "https://www.uniprot.org/uniprotkb/ARBA00094198#function" }, { "database": "UniProtKB", "id": "A0A287ALX0", "url": "https://www.uniprot.org/uniprotkb/A0A287ALX0#function" }, { "database": "UniProtKB", "id": "A0A8D1GCI9", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GCI9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DNAJC10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0", "locus": { "chromosome": "15", "start_pos": 88259002, "end_pos": 88198794, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016017", "url": "https://www.ensembl.org/id/ENSSSCG00000016017" } ] } } ], "crossref": [ { "id": "ENSSSCG00000016017", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016017", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03003", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03003", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03004", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03004", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523288", "url": "https://www.ncbi.nlm.nih.gov/gene/100523288", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035673", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035673", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523288", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523288", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SQF0", "url": "https://www.orthodb.org/?gene=A0A4X1SQF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44340:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44340:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020931971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931971", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21064", "url": "https://www.rhea-db.org/rhea/21064", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287ALX0", "url": "https://www.uniprot.org/uniprotkb/A0A287ALX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ALX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ALX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SQF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1GCI9", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GCI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1GCI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GCI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCH8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYL5", "url": "https://www.uniprot.org/uniprotkb/F1RYL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYL5-1", "url": "https://www.uniprot.org/uniprotkb/F1RYL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVWLNKDAYIRDLKRVILCFLLVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHSDFLKINKAYEVLKDEDLRKKYDKYGEKGLADNQGGGQYESWNYYRYDFGIYDDDPEIITLDRSEFDAAVNSGELWFVNFYSSGCSHCHDLAPTWRDFAREVDGLLRIGAVNCGDDRMLCRMKGVSSYPSLFIFRSGMAAVKYHGDRSKESLVNFAMQYVRSTVTELWTGNFVNSIQTAFAAGIGWLITFCSKGGDCLTSQTRLRLSGMLDGLVNVGWMDCATQDNLCKSLDITTSTTAYFPPGATLNNKEKSSILFLNSLDAKEIYLEIMHNLPDFELLSANTLEDRLAHHRWLLFFYFGKNEFSNDPELKKLKTLLKNEHIQVGKFDCSSAPDICSNLYVFQPCLAVFKGQGTKEFEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPTSDKEPWLVDFFAPWCPPCRALLPELRKASKHLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGHHSAEQILEFVEDLMNPSVVSLTPTTFDELVRQRKPDEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQQYHSLCAQENVRRYPEIRFFPQKSNKAYQYHSYNGWNRDAYSLRIWGLGFLPQASIDLTPQTFNEKVLQGKSHWVVDFYAPWCGPCQNFAPEFELLARMVKEKVKAGKVDCQAYAQTCQKAGIRAYPTVKFYPYEGTRRNIWGEQIDSRDAKEITTLIYEKLENLQNHGKRNKDEL", "length": 794, "header": "tr|A0A4X1SQF0-1|A0A4X1SQF0_PIG Isoform 1 of DnaJ homolog subfamily C member 10 OS=Sus scrofa OX=9823 GN=DNAJC10 PE=1 SV=1 CANONICAL=A0A4X1SQF0-1" }, "isoforms": [ { "isoform_ac": "A0A287ALX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0/entry#A0A287ALX0-1", "sequence": { "sequence": "MGVWLNKDAYIRDLKRVILCFLLVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHSDFLKINKAYEVLKDEDLRKKYDKYGEKGLADNQGGGQYESWNYYRYDFGIYDDDPEIITLDRSEFDAAVNSGELWFVNFYSSGCSHCHDLAPTWRDFAREVDGLLRIGAVNCGDDRMLCRMKGVSSYPSLFIFRSGMAAVKYHGDRSKESLVNFAMQYVRSTVTELWTGNFVNSIQTAFAAGIGWLITFCSKGGDCLTSQTRLRLSGMLDGLVNVGWMDCATQDNLCKSLDITTSTTAYFPPGATLNNKEKSSILFLNSLDAKEIYLEIMHNLPDFELLSANTLEVGKFDCSSAPDICSNLYVFQPCLAVFKGQGTKEFEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPTSDKEPWLVDFFAPWCPPCRALLPELRKASKHLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGHHSAEQILEFVEDLMNPSVVSLTPTTFDELVRQRKPDEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQQYHSLCAQENVRRYPEIRFFPQKSNKAYQYHSYNGWNRDAYSLRIWGLGFLPQASIDLTPQTFNEKVLQGKSHWVVDFYAPWCGPCQNFAPEFELLARMVKEKVKAGKVDCQAYAQTCQKAGIRAYPTVKFYPYEGTRRNIWGEQIDSRDAKEITTLIYEKLENLQNHGKRNKVRNLEFTLTNII", "length": 765, "header": "tr|A0A287ALX0-1|A0A4X1SQF0_PIG Computationally mapped isoform of DnaJ homolog subfamily C member 10 OS=Sus scrofa OX=9823 GN=DNAJC10 PE=1 SV=1 CANONICAL=A0A4X1SQF0-1" }, "locus": { "chromosome": "15", "start_pos": 88254463, "end_pos": 88200649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055807.2", "url": "https://www.ensembl.org/id/ENSSSCT00000055807.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044908.2", "url": "https://www.ensembl.org/id/ENSSSCP00000044908.2" } ] } }, { "isoform_ac": "A0A4X1SQF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0/entry#A0A4X1SQF0-1", "sequence": { "sequence": "MGVWLNKDAYIRDLKRVILCFLLVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHSDFLKINKAYEVLKDEDLRKKYDKYGEKGLADNQGGGQYESWNYYRYDFGIYDDDPEIITLDRSEFDAAVNSGELWFVNFYSSGCSHCHDLAPTWRDFAREVDGLLRIGAVNCGDDRMLCRMKGVSSYPSLFIFRSGMAAVKYHGDRSKESLVNFAMQYVRSTVTELWTGNFVNSIQTAFAAGIGWLITFCSKGGDCLTSQTRLRLSGMLDGLVNVGWMDCATQDNLCKSLDITTSTTAYFPPGATLNNKEKSSILFLNSLDAKEIYLEIMHNLPDFELLSANTLEDRLAHHRWLLFFYFGKNEFSNDPELKKLKTLLKNEHIQVGKFDCSSAPDICSNLYVFQPCLAVFKGQGTKEFEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPTSDKEPWLVDFFAPWCPPCRALLPELRKASKHLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGHHSAEQILEFVEDLMNPSVVSLTPTTFDELVRQRKPDEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQQYHSLCAQENVRRYPEIRFFPQKSNKAYQYHSYNGWNRDAYSLRIWGLGFLPQASIDLTPQTFNEKVLQGKSHWVVDFYAPWCGPCQNFAPEFELLARMVKEKVKAGKVDCQAYAQTCQKAGIRAYPTVKFYPYEGTRRNIWGEQIDSRDAKEITTLIYEKLENLQNHGKRNKDEL", "length": 794, "header": "tr|A0A4X1SQF0-1|A0A4X1SQF0_PIG Isoform 1 of DnaJ homolog subfamily C member 10 OS=Sus scrofa OX=9823 GN=DNAJC10 PE=1 SV=1 CANONICAL=A0A4X1SQF0-1" }, "locus": { "chromosome": "15", "start_pos": 88255558, "end_pos": 88200649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061963.1", "url": "https://www.ensembl.org/id/ENSSSCT00000061963.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033839.1", "url": "https://www.ensembl.org/id/ENSSSCP00000033839.1" } ] } }, { "isoform_ac": "A0A8D1GCI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0/entry#A0A8D1GCI9-1", "sequence": { "sequence": "MGVWLNKDAYIRDLKRVILCFLLVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHSDFLKINKAYEVLKDEDLRKKYDKYGEKGLADNQGGGQYESWNYYRYDFGIYDDDPEIITLDRSEFDAAVNSGELWFVNFYSSGCSHCHDLAPTWRDFAREVDGLLRIGAVNCGDDRMLCRMKGVSSYPSLFIFRSGMAAVKYHGDRSKESLVNFAMQYVRSTVTELWTGNFVNSIQTAFAAGIGWLITFCSKGGDCLTSQTRLRLSGMLDGLVNVGWMDCATQDNLCKSLDITTSTTAYFPPGATLNNKEKSSILFLNSLDAKEIYLEIMHNLPDFELLSANTLEDRLAHHRWLLFFYFGKNEFSNDPELKKLKTLLKNEHIQVGKFDCSSAPDICSNLYVFQPCLAVFKGQGTKEFEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPTSDKEPWLVDFFAPWCPPCRALLPELRKASKHLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGHHSAEQILEFVEDLMNPSVVSLTPTTFDELVRQRKPDEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQQYHSLCAQENVRRYPEIRFFPQKSNKAYQYHSYNGWNRDAYSLRIWGLGFLPQASIDLTPQTFNEKVLQGKSHWVVDFYAPWCGPCQNFAPEFELLARMVKEKVKAGKVDCQAYAQTCQKAGIRAYPTVKFYPYEGTRRNIWGEQIDSRDAKEITTLIYEKLENLQNHGKRNKVRNLEFTLTNII", "length": 803, "header": "tr|A0A8D1GCI9-1|A0A4X1SQF0_PIG Computationally mapped isoform of DnaJ homolog subfamily C member 10 OS=Sus scrofa OX=9823 GN=DNAJC10 PE=1 SV=1 CANONICAL=A0A4X1SQF0-1" }, "locus": { "chromosome": "15", "start_pos": 88254463, "end_pos": 88200649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063475.2", "url": "https://www.ensembl.org/id/ENSSSCT00000063475.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037219.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037219.2" } ] } }, { "isoform_ac": "A0A8W4FCH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0/entry#A0A8W4FCH8-1", "sequence": { "sequence": "MGVWLNKDAYIRDLKRVILCFLLVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHSDFLKINKAYEVLKDEDLRKKYDKYGEKGLADNQGGGQYESWNYYRYDFGIYDDDPEIITLDRSEFDAAVNSGELWFVNFYSSGCSHCHDLAPTWRDFAREVDGLLRIGAVNCGDDRMLCRMKGVSSYPSLFIFRSGMAAVKYHGDRSKESLVNFAMQYVRSTVTELWTGNFVNSIQTAFAAGIGWLITFCSKGGDCLTSQTRLRLSGMLFLNSLDAKEIYLEIMHNLPDFELLSANTLEDRLAHHRWLLFFYFGKNEFSNDPELKKLKTLLKNEHIQVGKFDCSSAPDICSNLYVFQPCLAVFKGQGTKEFEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPTSDKEPWLVDFFAPWCPPCRALLPELRKASKHLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGHHSAEQILEFVEDLMNPSVVSLTPTTFDELVRQRKPDEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQQYHSLCAQENVRRYPEIRFFPQKSNKAYQYHSYNGWNRDAYSLRIWGLGFLPQASIDLTPQTFNEKVLQGKSHWVVDFYAPWCGPCQNFAPEFELLARMVKEKVKAGKVDCQAYAQTCQKAGIRAYPTVKFYPYEGTRRNIWGEQIDSRDAKEITTLIYEKLENLQNHGKRNKVRNLEFTLTNII", "length": 757, "header": "tr|A0A8W4FCH8-1|A0A4X1SQF0_PIG Computationally mapped isoform of DnaJ homolog subfamily C member 10 OS=Sus scrofa OX=9823 GN=DNAJC10 PE=1 SV=1 CANONICAL=A0A4X1SQF0-1" }, "locus": { "chromosome": "15", "start_pos": 88254463, "end_pos": 88200649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102771.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102771.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077020.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077020.1" } ] } }, { "isoform_ac": "F1RYL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0/entry#F1RYL5-1", "sequence": { "sequence": "MGVWLNKDAYIRDLKRVILCFLLVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHSDFLKINKAYEVLKDEDLRKKYDKYGEKGLADNQGGGQYESWNYYRYDFGIYDDDPEIITLDRSEFDAAVNSGELWFVNFYSSGCSHCHDLAPTWRDFAREVDGLLRIGAVNCGDDRMLCRMKGVSSYPSLFIFRSGMAAVKYHGDRSKESLVNFAMQYVRSTVTELWTGNFVNSIQTAFAAGIGWLITFCSKGGGKKILYDILAFAKESVNSHVTTLGPQNFPTSDKEPWLVDFFAPWCPPCRALLPELRKASKHLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGHHSAEQILEFVEDLMNPSVVSLTPTTFDELVRQRKPDEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQQYHSLCAQENVRRYPEIRFFPQKSNKAYQYHSYNGWNRDAYSLRIWGLGFLPQASIDLTPQTFNEKVLQGKSHWVVDFYAPWCGPCQNFAPEFELLARMVKEKVKAGKVDCQAYAQTCQKAGIRAYPTVKFYPYEGTRRNIWGEQIDSRDAKEITTLIYEKLENLQNHGKRNKDEL", "length": 627, "header": "tr|F1RYL5-1|A0A4X1SQF0_PIG Computationally mapped isoform of DnaJ homolog subfamily C member 10 OS=Sus scrofa OX=9823 GN=DNAJC10 PE=1 SV=4 CANONICAL=A0A4X1SQF0-1" }, "locus": { "chromosome": "15", "start_pos": 88255558, "end_pos": 88200649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017440.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017440.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016971.5", "url": "https://www.ensembl.org/id/ENSSSCP00000016971.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FCH8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCH8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523288", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523288", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" }, { "name": "endoplasmic reticulum chaperone complex", "id": "GO:0034663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034663", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" }, { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor", "id": "GO:0016671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016671", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" }, { "name": "misfolded protein binding", "id": "GO:0051787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051787", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" }, { "name": "protein folding in endoplasmic reticulum", "id": "GO:0034975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034975", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" }, { "name": "IRE1-mediated unfolded protein response", "id": "GO:0036498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036498", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "id": "GO:0070059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070059", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21064", "name": "", "equation": "[protein]-disulfide + 2 glutathione = [protein]-dithiol + glutathione disulfide", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "21064", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21064" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SQF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 100, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SQF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF0" }, { "id": "PS51352", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 235, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 531, "end_pos": 533 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RH94-1", "uniprot_ac": "A0A5G2RH94", "uniprot_id": "A0A5G2RH94_PIG", "mass": { "chemical_mass": 45104.0, "monoisotopic_mass": 45104.0 }, "refseq": {}, "gene_names": [ { "name": "NEU1", "type": "recommended", "evidence": [ { "id": "A0A5G2RH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94" } ] } ], "protein_names": [ { "name": "Sialidase-1", "type": "recommended", "evidence": [ { "id": "A0A5G2RH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.18", "type": "synonym", "evidence": [ { "id": "A0A5G2RH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94/entry#names_and_taxonomy" } ] }, { "name": "Lysosomal sialidase", "type": "synonym", "evidence": [ { "id": "A0A5G2RH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94/entry#names_and_taxonomy" } ] }, { "name": "N-acetyl-alpha-neuraminidase 1", "type": "synonym", "evidence": [ { "id": "A0A5G2RH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94#function" }, { "database": "UniProtKB", "id": "ARBA00037235", "url": "https://www.uniprot.org/uniprotkb/ARBA00037235#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NEU1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94", "locus": { "chromosome": "7", "start_pos": 23953499, "end_pos": 23958638, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001418", "url": "https://www.ensembl.org/id/ENSSSCG00000001418" } ] } } ], "crossref": [ { "id": "A0A5G2RH94", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RH94", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001418", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001418", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15482", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15482", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR011040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IRSYDAC", "url": "https://omabrowser.org/oma/group/IRSYDAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10628", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10628", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10628:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10628:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13088", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13088", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RH94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RH94-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAERPGAVPLGRPGRPPMLGLGEAYRAQVFASIFLLLLSPAGVGARAKNDFSLVHPLVTMEQLLWVSGKQIGSVDTFRIPLITTTPRGTLLAFAEARKMSASDKGAKFIALRRSMDQGSTWSPTAFIVDDGETPDGLNLGAVVSDTTTGVVFLFYSLCAHKAGCRVASTMLVWSKDDGISWSSPRNLSLDIGTEMFAPGPGSGIQKQWAPQKGRLIVCGHGTLERDGVFCLLSDDHGASWRYGSGISGIPYGQPKRENDFNPDECQPYELPDGSVVINARNQNNYHCRCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGAVATSSGIIFFSNPAHPEFRVNLTLRWSFSNGTSWRKETVQIWPGPSGYSSLATLEGSVGGEDQAPQLYVLYEKGRNQYTESISLAKVSVYGTL", "length": 416, "header": "tr|A0A5G2RH94-1|A0A5G2RH94_PIG Isoform 1 of Sialidase-1 OS=Sus scrofa OX=9823 GN=NEU1 PE=3 SV=1 CANONICAL=A0A5G2RH94-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RH94-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94/entry#A0A5G2RH94-1", "sequence": { "sequence": "MTAERPGAVPLGRPGRPPMLGLGEAYRAQVFASIFLLLLSPAGVGARAKNDFSLVHPLVTMEQLLWVSGKQIGSVDTFRIPLITTTPRGTLLAFAEARKMSASDKGAKFIALRRSMDQGSTWSPTAFIVDDGETPDGLNLGAVVSDTTTGVVFLFYSLCAHKAGCRVASTMLVWSKDDGISWSSPRNLSLDIGTEMFAPGPGSGIQKQWAPQKGRLIVCGHGTLERDGVFCLLSDDHGASWRYGSGISGIPYGQPKRENDFNPDECQPYELPDGSVVINARNQNNYHCRCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGAVATSSGIIFFSNPAHPEFRVNLTLRWSFSNGTSWRKETVQIWPGPSGYSSLATLEGSVGGEDQAPQLYVLYEKGRNQYTESISLAKVSVYGTL", "length": 416, "header": "tr|A0A5G2RH94-1|A0A5G2RH94_PIG Isoform 1 of Sialidase-1 OS=Sus scrofa OX=9823 GN=NEU1 PE=3 SV=1 CANONICAL=A0A5G2RH94-1" }, "locus": { "chromosome": "7", "start_pos": 23958519, "end_pos": 23954268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090675.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090675.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074519.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074519.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "O35657-1", "protein_name": "Sialidase-1", "gene_name": "Neu1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGADPTRPRGPLSYWAGRRGQGLAAIFLLLVSAAESEARAEDDFSLVQPLVTMEQLLWVSGKQIGSVDTFRIPLITATPRGTLLAFAEARKKSASDEGAKFIAMRRSTDQGSTWSSTAFIVDDGEASDGLNLGAVVNDVDTGIVFLIYTLCAHKVNCQVASTMLVWSKDDGISWSPPRNLSVDIGTEMFAPGPGSGIQKQREPGKGRLIVCGHGTLERDGVFCLLSDDHGASWHYGTGVSGIPFGQPKHDHDFNPDECQPYELPDGSVIINARNQNNYHCRCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGALATSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWQKERVQVWPGPSGYSSLTALENSTDGKKQPPQLFVLYEKGLNRYTESISMVKISVYGTL", "length": 409 }, "evidence": [ { "id": "A0A5G2RH94", "url": "https://omabrowser.org/oma/group/A0A5G2RH94/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99519-1", "protein_name": "Sialidase-1", "gene_name": "NEU1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTMEQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGSTWSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVSWSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASWRYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKETVQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL", "length": 415 }, "evidence": [ { "id": "A0A5G2RH94", "url": "https://omabrowser.org/oma/group/A0A5G2RH94/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99PW3-1", "protein_name": "Sialidase-1", "gene_name": "Neu1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVGAEPSRPPGPPSYWTGRRGQGLAAIFLLLVSAAGSEARTEDDFSLVQPLVTMEQLLWVSGKQIGSVDTFRIPLITATPRGTLLAFAEARKKSASDEGAKFIAMRRSTDQGSTWSSTAFIVDDGEASDGLNLGAVVNDVDTGVVFLIYTLCAHKVNCQVASTMLVWSKDDGVSWSPPRNLSVDIGTEMFAPGPGSGIQKQREPWKGRLIVCGHGTLERDGVFCLLSDDHGASWHYGTGVSGIPFGQPKHDHDFNPDECQPYELPDGSVIINARNQNNYHCRCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGALATSSGIVFFSNPAHPEYRVNLTLRWSFSNGTFWQKERVQLWPGPSGYSSLTALENSTDGKKQPPQLFVLYEKGLNRYTESISMVKISVYGTL", "length": 409 }, "evidence": [ { "id": "A0A5G2RH94", "url": "https://omabrowser.org/oma/group/A0A5G2RH94/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94" } ], "pmid": "" }, { "name": "lysosomal lumen", "id": "GO:0043202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043202", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94" } ], "pmid": "" }, { "name": "oligosaccharide catabolic process", "id": "GO:0009313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009313", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "exo-alpha-sialidase activity", "id": "GO:0004308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004308", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RH94-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 416, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RH94-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RH94" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH94" }, { "id": "PF13088", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13088" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sialidase", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 378, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 353, "end_pos": 355 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1UQJ5-1", "uniprot_ac": "A0A5K1UQJ5", "uniprot_id": "A0A5K1UQJ5_PIG", "mass": { "chemical_mass": 49058.0, "monoisotopic_mass": 49058.0 }, "refseq": { "ac": "XP_005664884", "name": "protein tweety homolog 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664884" }, "gene_names": [ { "name": "TTYH1", "type": "recommended", "evidence": [ { "id": "A0A5K1UQJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ] }, { "name": "TTYH1", "type": "synonym", "evidence": [ { "id": "XP_005664884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664884" } ] } ], "protein_names": [ { "name": "Protein tweety homolog", "type": "recommended", "evidence": [ { "id": "A0A5K1UQJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5/entry#names_and_taxonomy" } ] }, { "name": "protein tweety homolog 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005664884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664884" } ] } ], "function": [ { "annotation": "Calcium-independent, swelling-dependent volume-regulated anion channel (VRAC-swell) which plays a pivotal role in the process of regulatory volume decrease (RVD) in the brain through the efflux of anions like chloride and organic osmolytes like glutamate.", "evidence": [ { "database": "UniProtKB", "id": "F1RNG6", "url": "https://www.uniprot.org/uniprotkb/F1RNG6#function" }, { "database": "UniProtKB", "id": "ARBA00044730", "url": "https://www.uniprot.org/uniprotkb/ARBA00044730#function" }, { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5#function" }, { "database": "UniProtKB", "id": "A0A8W4FA20", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FA20#function" }, { "database": "UniProtKB", "id": "A0A8W4FAK1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAK1#function" } ] }, { "annotation": "Probable chloride channel.", "evidence": [ { "database": "UniProtKB", "id": "F1RNG6", "url": "https://www.uniprot.org/uniprotkb/F1RNG6#function" }, { "database": "UniProtKB", "id": "RU361114", "url": "https://www.uniprot.org/uniprotkb/RU361114#function" }, { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5#function" }, { "database": "UniProtKB", "id": "A0A8W4FA20", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FA20#function" }, { "database": "UniProtKB", "id": "A0A8W4FAK1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAK1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TTYH1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5", "locus": { "chromosome": "6", "start_pos": 58871665, "end_pos": 58891519, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003271", "url": "https://www.ensembl.org/id/ENSSSCG00000003271" } ] } } ], "crossref": [ { "id": "ENSSSCG00000003271", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003271", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524682", "url": "https://www.ncbi.nlm.nih.gov/gene/100524682", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524682", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524682", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DFCSEPN", "url": "https://omabrowser.org/oma/group/DFCSEPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5K1UQJ5", "url": "https://www.orthodb.org/?gene=A0A5K1UQJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12424", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12424", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12424:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12424:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005664884", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664884", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "66336", "url": "https://www.rhea-db.org/rhea/66336", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UQJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FA20", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FA20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FA20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FA20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAK1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RNG6", "url": "https://www.uniprot.org/uniprotkb/F1RNG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RNG6-1", "url": "https://www.uniprot.org/uniprotkb/F1RNG6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGAKSPPPGGGCVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALLHANHTLKAIDHLVLEMVERLGEAVRTELTTLEEVLTQRTELVAAARGARRQAEAVAQQLQGLAFWRGVPLSPVQVAEDVSYVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMGLLVLVLSWGSMGLEAATAVGLSDFCSSPDMYILNLTQEETGLGSDILNYYFLCNQEVSNPFQQRLTLSQRALANIHSQLQGLEREAVPQFPSAQKPLLSLEETLNTTEGNLHQLVALLHCRGLHKDYGTALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPSDDYDDTDDDDPFSPQESKRFVQWQSSI", "length": 450, "header": "tr|A0A5K1UQJ5-1|A0A5K1UQJ5_PIG Isoform 1 of Protein tweety homolog OS=Sus scrofa OX=9823 GN=TTYH1 PE=1 SV=1 CANONICAL=A0A5K1UQJ5-1" }, "isoforms": [ { "isoform_ac": "A0A5K1UQJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5/entry#A0A5K1UQJ5-1", "sequence": { "sequence": "MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGAKSPPPGGGCVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALLHANHTLKAIDHLVLEMVERLGEAVRTELTTLEEVLTQRTELVAAARGARRQAEAVAQQLQGLAFWRGVPLSPVQVAEDVSYVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMGLLVLVLSWGSMGLEAATAVGLSDFCSSPDMYILNLTQEETGLGSDILNYYFLCNQEVSNPFQQRLTLSQRALANIHSQLQGLEREAVPQFPSAQKPLLSLEETLNTTEGNLHQLVALLHCRGLHKDYGTALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPSDDYDDTDDDDPFSPQESKRFVQWQSSI", "length": 450, "header": "tr|A0A5K1UQJ5-1|A0A5K1UQJ5_PIG Isoform 1 of Protein tweety homolog OS=Sus scrofa OX=9823 GN=TTYH1 PE=1 SV=1 CANONICAL=A0A5K1UQJ5-1" }, "locus": { "chromosome": "6", "start_pos": 58891448, "end_pos": 58876272, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025769.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025769.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020471.2", "url": "https://www.ensembl.org/id/ENSSSCP00000020471.2" } ] } }, { "isoform_ac": "A0A8W4FA20-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5/entry#A0A8W4FA20-1", "sequence": { "sequence": "MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGAKSPPPGGGCVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALLHANHTLKAIDHLVLEMVERLGEAVRTELTTLEEVLTQRTELVAAARGARRQAEAVAQQLQGLAFWRGVPLSPVQVAEDVSYVEEYRMTVMGLLVLVLSWGSMGLEAATAVGLSDFCSSPDMYILNLTQEETGLGSDILNYYFLCNQEVSNPFQQRLTLSQRALANIHSQLQGLEREAVPQFPSAQKPLLSLEETLNTTEGNLHQLVALLHCRGLHKDYGTALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPRNPSASCSGSHLSEPLLQARRASVPHLRVFPGCQRRPR", "length": 428, "header": "tr|A0A8W4FA20-1|A0A5K1UQJ5_PIG Computationally mapped isoform of Protein tweety homolog OS=Sus scrofa OX=9823 GN=TTYH1 PE=1 SV=1 CANONICAL=A0A5K1UQJ5-1" }, "locus": { "chromosome": "6", "start_pos": 58891448, "end_pos": 58876053, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102502.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102502.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076236.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076236.1" } ] } }, { "isoform_ac": "A0A8W4FAK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5/entry#A0A8W4FAK1-1", "sequence": { "sequence": "MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGAKSPPPGGGCVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALLHANHTLKAIDHLVLEMVERLGEAVRTELTTLEEVLTQRTELVAAARGARRQAEAVAQQLQGLAFWRGVPLSPVQVAEDVSYVEEYRMTVMGLLVLVLSWGSMGLEAATAVGLSDFCSSPDMYILNLTQEETGLGSDILNYYFLCNQEVSNPFQQRLTLSQRALANIHSQLQGLEREAVPQFPSAQKPLLSLEETLNTTEGNLHQLVALLHCRGLHKDYGTALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPSDDYDDTDDDDPFSPQESKRFVQWQSSI", "length": 418, "header": "tr|A0A8W4FAK1-1|A0A5K1UQJ5_PIG Computationally mapped isoform of Protein tweety homolog OS=Sus scrofa OX=9823 GN=TTYH1 PE=1 SV=1 CANONICAL=A0A5K1UQJ5-1" }, "locus": { "chromosome": "6", "start_pos": 58891448, "end_pos": 58876272, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103476.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103476.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076349.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076349.1" } ] } }, { "isoform_ac": "F1RNG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5/entry#F1RNG6-1", "sequence": { "sequence": "MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGAKSPPPGGGCVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALLHANHTLKAIDHLVLEMVERLGEAVRTELTTLEEVLTQRTELVAAARGARRQAEAVAQQLQGLAFWRGVPLSPVQVAEDVSYVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMGLLVLVLSWGSMGLEAATAVGLSDFCSSPDMYILNLTQEETGLGSDILNYYFLCNQEVSNPFQQRLTLSQRALANIHSQLQGLEREAVPQFPSAQKPLLSLEETLNTTEGNLHQLVALLHCRGLHKDYGTALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPSDDYDDTDDDDPFSPQVPPGIQALRAVAVIYLSPSSRPDGRLFPISVSSLAAREDPANPAAGPPH", "length": 487, "header": "tr|F1RNG6-1|A0A5K1UQJ5_PIG Computationally mapped isoform of Protein tweety homolog OS=Sus scrofa OX=9823 GN=TTYH1 PE=1 SV=3 CANONICAL=A0A5K1UQJ5-1" }, "locus": { "chromosome": "6", "start_pos": 58891448, "end_pos": 58876028, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003632.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003632.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003547.4", "url": "https://www.ensembl.org/id/ENSSSCP00000003547.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FA20", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FA20" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524682", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524682", "resource": "KEGG Pathway" }, { "id": "R-SSC-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N0P0-1", "protein_name": "Protein tweety homolog", "gene_name": "TTYH1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSAFAPQEREYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGAKSPPPGGGCVTWNCIAALLVGCAGIGVGFYGNSETSDGVSQLSSALLHANHTLTAIDHLVLEMVERLDEAVRTELTTLEEVLTQRTELVAAARGARRQAETVAQQLQGLAFWRGVPLSPLQVAEDVSFVEEYRWLAYVLLLLLELLVCLFTLLGLARQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSSPDSYILNLTQEETGLGSDILNYYFLCNQAVSNPFQQRLTLSQRALANIHSQLQGLEREAVPQFPSAQKPVLSLEETLNVTEGNFHQLVALLHCRGLHKDYGSALRGLCEDTLEGLLFLLLFSLLSAGALATVLCSLPRAWALFPPSDDYEDTDDDDPFNPQESKRFVQWQSSI", "length": 450 }, "evidence": [ { "id": "A0A5K1UQJ5", "url": "https://omabrowser.org/oma/group/A0A5K1UQJ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C5X8-1", "protein_name": "Protein tweety homolog 1", "gene_name": "Ttyh1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPRDQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGAKSPPPGGGCVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALQHANHTLSTIDDLVLETVERLGEAVRTELTTLEEVLSERVELVAATRGARRQAEAAAQHLQGLAFWQGVSLSPVQVAEDVTFVEEYRWLAYVLLLLLVLLVCLFTLLGLAKQSKWLVVVMTAMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDTYVLNLTQEETGISSDILNYYFLCNQAVSNPFQQRLTLSQRALASIHSQLQGLEREASPQFPAAQKPLLSLEETLNVTERSFHQLVALLHCRSLHKDYGSALRGLCEDALEGLLFLMLFSLLSAGALATTLCSLPRAWALFPPSDDYDDTDDDDPFNPQESKRFVQWQSSI", "length": 450 }, "evidence": [ { "id": "A0A5K1UQJ5", "url": "https://omabrowser.org/oma/group/A0A5K1UQJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D3A9-1", "protein_name": "Protein tweety homolog 1", "gene_name": "Ttyh1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPRDQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPHGAKSPPPGGGCVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDDVVLETVERLGEAVKTELTTLEEVLSVRMELVAATRGARRQAEAAAQYLQGLAFWQGVSLSPVQVAEDVTFVEEYRWLAYVLLLLLVLLVCLFTLLGLAKQSKWLVVVMTAMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDTYVLNLTQEETGLSSDILSYYFLCNQAVSNPFQQRLTLSQRALASIHSQLQGLEREAIPQFSAAQKPLLSLEETLNVTERSFHQLVALLHCRSLHKDYGSALRGLCEDALEGLLFLMLFSLLSAGALATTLCSLPRAWALFPPSDDYDDTDDDDPFNPQESKRFVQWQSSI", "length": 450 }, "evidence": [ { "id": "A0A5K1UQJ5", "url": "https://omabrowser.org/oma/group/A0A5K1UQJ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H313-1", "protein_name": "Protein tweety homolog 1", "gene_name": "TTYH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPSDDYDDTDDDDPFNPQESKRFVQWQSSI", "length": 450 }, "evidence": [ { "id": "A0A5K1UQJ5", "url": "https://omabrowser.org/oma/group/A0A5K1UQJ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "volume-sensitive chloride channel activity", "id": "GO:0072320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072320", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ], "pmid": "" }, { "name": "intracellularly calcium-gated chloride channel activity", "id": "GO:0005229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005229", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ], "pmid": "" }, { "name": "smooth endoplasmic reticulum membrane", "id": "GO:0030868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030868", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ], "pmid": "" }, { "name": "filopodium membrane", "id": "GO:0031527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031527", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ], "pmid": "" }, { "name": "filopodium tip", "id": "GO:0032433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032433", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-glutamate transmembrane transport", "id": "GO:0015813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015813", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UQJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29823", "name": "", "equation": "chloride(in) = chloride(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29823", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29823" } ] }, { "id": "66336", "name": "", "equation": "L-glutamate(out) = L-glutamate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "66336", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/66336" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 355, "end_pos": 357 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1ST70-1", "uniprot_ac": "A0A4X1ST70", "uniprot_id": "A0A4X1ST70_PIG", "mass": { "chemical_mass": 7701.0, "monoisotopic_mass": 7701.0 }, "refseq": { "ac": "XP_003358133", "name": "guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358133" }, "gene_names": [ { "name": "LOC110255211", "type": "recommended", "evidence": [ { "id": "A0A4X1ST70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70" } ] }, { "name": "LOC110255211", "type": "synonym", "evidence": [ { "id": "XP_003358133", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358133" } ] } ], "protein_names": [ { "name": "Guanine nucleotide-binding protein subunit gamma", "type": "recommended", "evidence": [ { "id": "A0A4X1ST70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70/entry#names_and_taxonomy" } ] }, { "name": "guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003358133", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358133" } ] } ], "function": [ { "annotation": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ADM2", "url": "https://www.uniprot.org/uniprotkb/A0A287ADM2#function" }, { "database": "UniProtKB", "id": "RU004973", "url": "https://www.uniprot.org/uniprotkb/RU004973#function" }, { "database": "UniProtKB", "id": "A0A4X1ST70", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST70", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110255211", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70", "locus": {} } ], "crossref": [ { "id": "A0A4X1ST70", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1ST70", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000040110", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000040110", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00068", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00068", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110255211", "url": "https://www.ncbi.nlm.nih.gov/gene/110255211", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110255211", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255211", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DWMESMA", "url": "https://omabrowser.org/oma/group/DWMESMA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1ST70", "url": "https://www.orthodb.org/?gene=A0A4X1ST70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1296041", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296041", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-202040", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202040", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-392170", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-392451", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392451", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4086398", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4086398", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418597", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-428930", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-428930", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-456926", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-456926", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6814122", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6814122", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8964616", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-997272", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003358133", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358133", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287ADM2", "url": "https://www.uniprot.org/uniprotkb/A0A287ADM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ADM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1ST70", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1ST70-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQDLSEKELLKMEVEQLKKEVKTPRALISKTGKEIKDYVEAEAGNDPLLKGIPEDKNPFKEKGGCLIS", "length": 69, "header": "tr|A0A4X1ST70-1|A0A4X1ST70_PIG Isoform 1 of Guanine nucleotide-binding protein subunit gamma OS=Sus scrofa OX=9823 GN=LOC110255211 PE=3 SV=1 CANONICAL=A0A4X1ST70-1" }, "isoforms": [ { "isoform_ac": "A0A287ADM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70/entry#A0A287ADM2-1", "sequence": { "sequence": "MISLGVRDLGFQTICFIQRLSADQEPGGSNPILSGSGTSGLKCTLLLGRTWSLRGRMAQDLSEKELLKMEVEQLKKEVKTPRALISKTGKEIKDYVEAEAGNDPLLKGIPEDKNPFKEKGGCLIS", "length": 125, "header": "tr|A0A287ADM2-1|A0A4X1ST70_PIG Computationally mapped isoform of Guanine nucleotide-binding protein subunit gamma OS=Sus scrofa OX=9823 GN=LOC110255211 PE=3 SV=1 CANONICAL=A0A4X1ST70-1" }, "locus": { "chromosome": "12", "start_pos": 25340612, "end_pos": 25338155, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042079.2", "url": "https://www.ensembl.org/id/ENSSSCT00000042079.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041932.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041932.2" } ] } }, { "isoform_ac": "A0A4X1ST70-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70/entry#A0A4X1ST70-1", "sequence": { "sequence": "MAQDLSEKELLKMEVEQLKKEVKTPRALISKTGKEIKDYVEAEAGNDPLLKGIPEDKNPFKEKGGCLIS", "length": 69, "header": "tr|A0A4X1ST70-1|A0A4X1ST70_PIG Isoform 1 of Guanine nucleotide-binding protein subunit gamma OS=Sus scrofa OX=9823 GN=LOC110255211 PE=3 SV=1 CANONICAL=A0A4X1ST70-1" }, "locus": { "chromosome": "12", "start_pos": 25340612, "end_pos": 25339414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044648.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044648.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054277.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054277.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ADM2", "url": "https://www.uniprot.org/uniprotkb/A0A287ADM2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110255211", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255211", "resource": "KEGG Pathway" }, { "id": "R-SSC-1296041", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296041", "resource": "Reactome", "description": "Activation of G protein gated Potassium channels" }, { "id": "R-SSC-202040", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202040", "resource": "Reactome", "description": "G-protein activation" }, { "id": "R-SSC-392170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392170", "resource": "Reactome", "description": "ADP signalling through P2Y purinoceptor 12" }, { "id": "R-SSC-392451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392451", "resource": "Reactome", "description": "G beta:gamma signalling through PI3Kgamma" }, { "id": "R-SSC-4086398", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4086398", "resource": "Reactome", "description": "Ca2+ pathway" }, { "id": "R-SSC-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-SSC-418597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418597", "resource": "Reactome", "description": "G alpha (z) signalling events" }, { "id": "R-SSC-428930", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-428930", "resource": "Reactome", "description": "Thromboxane signalling through TP receptor" }, { "id": "R-SSC-456926", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-456926", "resource": "Reactome", "description": "Thrombin signalling through proteinase activated receptors (PARs)" }, { "id": "R-SSC-6814122", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6814122", "resource": "Reactome", "description": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" }, { "id": "R-SSC-8964616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964616", "resource": "Reactome", "description": "G beta:gamma signalling through CDC42" }, { "id": "R-SSC-997272", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "resource": "Reactome", "description": "Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G-protein beta-subunit binding", "id": "GO:0031681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031681", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST70", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST70", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "heterotrimeric G-protein complex", "id": "GO:0005834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005834", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST70", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1ST70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST70" }, { "id": "PS50058", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50058" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G protein gamma", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 69, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RJF6-1", "uniprot_ac": "A0A5G2RJF6", "uniprot_id": "A0A5G2RJF6_PIG", "mass": { "chemical_mass": 120883.0, "monoisotopic_mass": 120883.0 }, "refseq": {}, "gene_names": [ { "name": "ADAMTS17", "type": "recommended", "evidence": [ { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ] } ], "protein_names": [ { "name": "ADAM metallopeptidase with thrombospondin type 1 motif 17", "type": "synonym", "evidence": [ { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ADAMTS17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6", "locus": { "chromosome": "1", "start_pos": 138619706, "end_pos": 139015473, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000038452", "url": "https://www.ensembl.org/id/ENSSSCG00000038452" } ] } } ], "crossref": [ { "id": "A0A5G2RJF6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RJF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000038452", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000038452", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "102160867", "url": "https://www.ncbi.nlm.nih.gov/gene/102160867", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723:SF151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723:SF151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5173214", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5173214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287ADP0", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ADP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCDGALLPPLVLPLLLLLVWGLDSGAAVGDAAADVEVVLPRRVRPDAVHLPQLPGAPGPRRRRRPRAPPAAPRARPGERALLLHLPAFGRDLYLQLRRDLRFLSGGFEVEEAGEAGRRGRPAELCFYSGRVLGHPGSLVSLSTCGGGLVGLIQLGQEQVLIQPLNSSQGQEHLIRRRWSLTPSPSAEAQMPGQPCKVLTEKKKPKRGRLSRDWRGRRSAIRLTNEHTVETLVVADADMVQYHGAEAAQRFILTVMNMVYNMFQHESLGIKVNIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPGGKDDTPPVDAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDDHSSCAGRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLLVTDPRSQHAVRLPHKLPGMHYSANEQCQILFGTNATFCRNLEHLMCAGLWCLVEGDTSCKTKLDPPLDGTECGADKWCRAGECVSKTPIPEHVDGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCLGASVEHAVCENLPCPKGLPSFRDQQCQTHDRLSSKKKGLLTAVVVDDKPCELHCLPLGKESPLLVADRVLDGTPCGPYETDLCVHGRCQKIGCDGIIGSAAKEDRCGVCSGDGKTCRVVKGDFSHSRGTALKDSSKRSINSDWKIELPGEFQIAGTTVRYVRRGLWEKISAKGPTKMPLHLMVLLFHDQNYGIHYEYTIPVNYTAENQSEPEKPQDSLFIWTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCNSHPCQSRWVAGPWSPCSATCEKGIQHREVTCVYQLQNGTHVATRPLYCPVPRPSPVQSCEGQDCLSIWEASEWSQCSANCGKGTRKRTVTCTNSQGKCDASRRPRAEEACEDYSGCYEWKTGSWSKCSSTCGKGLQSRVVQCMHKVTGRHGNECPALSKPAAYKQCHQEVCNDKINVNTITSPRLAALTYKCTRDQWTVYCRVIREKNLCQDMRWYQRCCQTCRDFYANKMRQQPPLPPPPSS", "length": 1094, "header": "tr|A0A5G2RJF6-1|A0A5G2RJF6_PIG Isoform 1 of ADAM metallopeptidase with thrombospondin type 1 motif 17 OS=Sus scrofa OX=9823 GN=ADAMTS17 PE=4 SV=1 CANONICAL=A0A5G2RJF6-1" }, "isoforms": [ { "isoform_ac": "A0A287ADP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6/entry#A0A287ADP0-1", "sequence": { "sequence": "MCDGALLPPLVLPLLLLLVWGLDSGAAVGDAAADVEVVLPRRVRPDAVHLPQLPGAPGPRRRRRPRAPPAAPRARPGERALLLHLPAFGRDLYLQLRRDLRFLSGGFEVEEAGEAGRRGRPAELCFYSGRVLGHPGSLVSLSTCGGGLVGLIQLGQEQVLIQPLNSSQGQEHLIRRRWSLTPSPSAEAQMPGQPCKVLTEKKKPKRGRLSRDWRGRRSAIRLTNEHTVETLVVADADMVQYHGAEAAQRFILTVMNMVYNMFQHESLGIKVNIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPGGKDDTPPVDAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDDHSSCAGRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLLVTDPRSQHAVRLPHKLPGMHYSANEQCQILFGTNATFCRNLEHLMCAGLWCLVEGDTSCKTKLDPPLDGTECGADKWCRAGECVSKTPIPEHVDGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCLGASVEHAVCENLPCPKGLPSFRDQQCQTHDRLSSKKKGLLTAVVVDDKPCELHCLPLGKESPLLVADRVLDGTPCGPYETDLCVHGRCQKIGCDGIIGSAAKEDRCGVCSGDGKTCRVVKGDFSHSRGTGYIEAVIIPAGARRIRVVEDKPAHSFLALKDSSKRSINSDWKIELPGEFQIAGTTVRYVRRGLWEKISAKGPTKMPLHLMVLLFHDQNYGIHYEYTIPVNYTAENQSEPEKPQDSLFIWTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCNSHPCQSRWVAGPWSPCSATCEKGIQHREVTCVYQLQNGTHVATRPLYCPVPRPSPVQSCEGQDCLSIWEASEWSQCSANCGKGTRKRTVTCTNSQGKCDASRRPRAEEACEDYSGCYEWKTGSWSKCSSTCGKGLQSRVVQCMHKVTGRHGNECPALSKPAAYKQCHQEVCNDKINVNTITSPRLAALTYKCTRDQWTVYCRVIREKNLCQDMRWYQRCCQTCRDFYANKMRQQPPLPPPPSS", "length": 1121, "header": "tr|A0A287ADP0-1|A0A5G2RJF6_PIG Computationally mapped isoform of ADAM metallopeptidase with thrombospondin type 1 motif 17 OS=Sus scrofa OX=9823 GN=ADAMTS17 PE=4 SV=2 CANONICAL=A0A5G2RJF6-1" }, "locus": { "chromosome": "1", "start_pos": 139015380, "end_pos": 138622470, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041094.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041094.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042131.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042131.2" } ] } }, { "isoform_ac": "A0A5G2RJF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6/entry#A0A5G2RJF6-1", "sequence": { "sequence": "MCDGALLPPLVLPLLLLLVWGLDSGAAVGDAAADVEVVLPRRVRPDAVHLPQLPGAPGPRRRRRPRAPPAAPRARPGERALLLHLPAFGRDLYLQLRRDLRFLSGGFEVEEAGEAGRRGRPAELCFYSGRVLGHPGSLVSLSTCGGGLVGLIQLGQEQVLIQPLNSSQGQEHLIRRRWSLTPSPSAEAQMPGQPCKVLTEKKKPKRGRLSRDWRGRRSAIRLTNEHTVETLVVADADMVQYHGAEAAQRFILTVMNMVYNMFQHESLGIKVNIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPGGKDDTPPVDAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDDHSSCAGRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLLVTDPRSQHAVRLPHKLPGMHYSANEQCQILFGTNATFCRNLEHLMCAGLWCLVEGDTSCKTKLDPPLDGTECGADKWCRAGECVSKTPIPEHVDGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCLGASVEHAVCENLPCPKGLPSFRDQQCQTHDRLSSKKKGLLTAVVVDDKPCELHCLPLGKESPLLVADRVLDGTPCGPYETDLCVHGRCQKIGCDGIIGSAAKEDRCGVCSGDGKTCRVVKGDFSHSRGTALKDSSKRSINSDWKIELPGEFQIAGTTVRYVRRGLWEKISAKGPTKMPLHLMVLLFHDQNYGIHYEYTIPVNYTAENQSEPEKPQDSLFIWTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCNSHPCQSRWVAGPWSPCSATCEKGIQHREVTCVYQLQNGTHVATRPLYCPVPRPSPVQSCEGQDCLSIWEASEWSQCSANCGKGTRKRTVTCTNSQGKCDASRRPRAEEACEDYSGCYEWKTGSWSKCSSTCGKGLQSRVVQCMHKVTGRHGNECPALSKPAAYKQCHQEVCNDKINVNTITSPRLAALTYKCTRDQWTVYCRVIREKNLCQDMRWYQRCCQTCRDFYANKMRQQPPLPPPPSS", "length": 1094, "header": "tr|A0A5G2RJF6-1|A0A5G2RJF6_PIG Isoform 1 of ADAM metallopeptidase with thrombospondin type 1 motif 17 OS=Sus scrofa OX=9823 GN=ADAMTS17 PE=4 SV=1 CANONICAL=A0A5G2RJF6-1" }, "locus": { "chromosome": "1", "start_pos": 139015380, "end_pos": 138622470, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067496.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067496.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071979.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071979.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ADP0", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJF6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 779, "end_pos": 781, "annotation": "n_glycosylation_sequon" }, { "start_pos": 784, "end_pos": 786, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 835, "annotation": "n_glycosylation_sequon" }, { "start_pos": 888, "end_pos": 890, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RJF6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1094, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RJF6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RJF6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" }, { "id": "PS50900", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50900" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLAC", "eco_id": "ECO_0000259", "start_pos": 1039, "end_pos": 1078, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" }, { "id": "PS50215", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50215" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M12B", "eco_id": "ECO_0000259", "start_pos": 226, "end_pos": 446, "start_aa": "His", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0#function" }, { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0" }, { "id": "PIRSR613273-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR613273-2" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6#function" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "binding_site_uniprot": 195, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic;in inhibited form", "eco_id": "ECO_0000256", "start_pos": 195, "end_pos": 195, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0#function" }, { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0" }, { "id": "PIRSR613273-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR613273-2" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6#function" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "binding_site_uniprot": 229, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 229, "end_pos": 229, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0#function" }, { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0" }, { "id": "PIRSR613273-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR613273-2" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6#function" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "binding_site_uniprot": 331, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 331, "end_pos": 331, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0#function" }, { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0" }, { "id": "PIRSR613273-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR613273-2" }, { "id": "PRU00276", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00276" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6#function" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "binding_site_uniprot": 383, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 383, "end_pos": 383, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0#function" }, { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0" }, { "id": "PIRSR613273-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR613273-2" }, { "id": "PRU00276", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00276" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6#function" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "binding_site_uniprot": 387, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 387, "end_pos": 387, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0#function" }, { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0" }, { "id": "PIRSR613273-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR613273-2" }, { "id": "PRU00276", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00276" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6#function" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "binding_site_uniprot": 393, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 393, "end_pos": 393, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0#function" }, { "id": "A0A287ADP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287ADP0" }, { "id": "PIRSR613273-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR613273-2" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6#function" }, { "id": "A0A5G2RJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJF6" } ], "binding_site_uniprot": 441, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 441, "end_pos": 441, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 477, "end_pos": 479 }, { "start_pos": 779, "end_pos": 781 }, { "start_pos": 784, "end_pos": 786 }, { "start_pos": 826, "end_pos": 828 }, { "start_pos": 833, "end_pos": 835 }, { "start_pos": 888, "end_pos": 890 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T2C1-1", "uniprot_ac": "A0A4X1T2C1", "uniprot_id": "A0A4X1T2C1_PIG", "mass": { "chemical_mass": 41129.0, "monoisotopic_mass": 41129.0 }, "refseq": { "ac": "XP_003481293", "name": "glutaminyl-peptide cyclotransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481293" }, "gene_names": [ { "name": "QPCT", "type": "recommended", "evidence": [ { "id": "A0A4X1T2C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1" } ] }, { "name": "QPCT", "type": "synonym", "evidence": [ { "id": "XP_003481293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481293" } ] } ], "protein_names": [ { "name": "Glutaminyl-peptide cyclotransferase", "type": "recommended", "evidence": [ { "id": "A0A4X1T2C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.5", "type": "synonym", "evidence": [ { "id": "A0A4X1T2C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1/entry#names_and_taxonomy" } ] }, { "name": "Glutaminyl cyclase", "type": "synonym", "evidence": [ { "id": "A0A4X1T2C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1/entry#names_and_taxonomy" } ] }, { "name": "Glutaminyl-tRNA cyclotransferase", "type": "synonym", "evidence": [ { "id": "A0A4X1T2C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1/entry#names_and_taxonomy" } ] }, { "name": "glutaminyl-peptide cyclotransferase", "type": "synonym", "evidence": [ { "id": "XP_003481293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481293" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2C1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "QPCT", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1", "locus": { "chromosome": "3", "start_pos": 102792720, "end_pos": 102823026, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008491", "url": "https://www.ensembl.org/id/ENSSSCG00000008491" } ] } } ], "crossref": [ { "id": "A0A4X1T2C1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T2C1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008491", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008491", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03880", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03880", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "397424", "url": "https://www.ncbi.nlm.nih.gov/gene/397424", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:397424", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:397424", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T2C1", "url": "https://www.orthodb.org/?gene=A0A4X1T2C1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12283", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12283", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12283:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12283:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003481293", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481293", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23652", "url": "https://www.rhea-db.org/rhea/23652", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A287AEJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AEJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AEJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T2C1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T2C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGSGDRRFVGTLHLLLLVATLSLAAQGVSRSAAAWTQEKSYHQPALLNLSSLRQVAEGTSISEMWQNDLRPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEVDTFLSRTPYGYRSFSNIISTLNPTAKRHLVLACHYDSKYFPHWDNRVFVGATDSAVPCAMILELARALDKQLLSLKNISDLKPDLSLQLIFFDGEEAFLHWSPHDSLYGSRHLASKMASTPHPPGARDTNQLHGMDLLILLDLIGAPNPTFPNFFPNSARWFDRLQAIEHELHVFGLLKDHSWERRYFQNYGYGGVIQDDHVPFLRKGVPVLHLIPSPFPEVWHTMDDNEENLDKTTIDNLNKILQVFVLEYLHL", "length": 361, "header": "tr|A0A4X1T2C1-1|A0A4X1T2C1_PIG Isoform 1 of Glutaminyl-peptide cyclotransferase OS=Sus scrofa OX=9823 GN=QPCT PE=1 SV=1 CANONICAL=A0A4X1T2C1-1" }, "isoforms": [ { "isoform_ac": "A0A287AEJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1/entry#A0A287AEJ1-1", "sequence": { "sequence": "MTGSGDRRFVGTLHLLLLVATLSLAAQGVSRSAAAWTQEKSYHQPALLNLSSLRQVAEGTSISEMWQNDLRPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEVDTFLSRTPYGYRSFSNIISTLNPTAKRHLVLACHYDSKYFPHWDNRVFVGATDSAVPCAMILELARIPGIKHITPNPTFPNFFPNSARWFDRLQAIEHELHVFGLLKDHSWERRYFQNYGYGGVIQDDHVPFLRKGVPVLHLIPSPFPEVWHTMDDNEENLDKTTIDNLNKILQVFVLEYLHL", "length": 289, "header": "tr|A0A287AEJ1-1|A0A4X1T2C1_PIG Computationally mapped isoform of Glutaminyl-peptide cyclotransferase OS=Sus scrofa OX=9823 GN=QPCT PE=1 SV=2 CANONICAL=A0A4X1T2C1-1" }, "locus": { "chromosome": "3", "start_pos": 102822956, "end_pos": 102795649, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041233.2", "url": "https://www.ensembl.org/id/ENSSSCT00000041233.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042235.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042235.2" } ] } }, { "isoform_ac": "A0A4X1T2C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1/entry#A0A4X1T2C1-1", "sequence": { "sequence": "MTGSGDRRFVGTLHLLLLVATLSLAAQGVSRSAAAWTQEKSYHQPALLNLSSLRQVAEGTSISEMWQNDLRPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEVDTFLSRTPYGYRSFSNIISTLNPTAKRHLVLACHYDSKYFPHWDNRVFVGATDSAVPCAMILELARALDKQLLSLKNISDLKPDLSLQLIFFDGEEAFLHWSPHDSLYGSRHLASKMASTPHPPGARDTNQLHGMDLLILLDLIGAPNPTFPNFFPNSARWFDRLQAIEHELHVFGLLKDHSWERRYFQNYGYGGVIQDDHVPFLRKGVPVLHLIPSPFPEVWHTMDDNEENLDKTTIDNLNKILQVFVLEYLHL", "length": 361, "header": "tr|A0A4X1T2C1-1|A0A4X1T2C1_PIG Isoform 1 of Glutaminyl-peptide cyclotransferase OS=Sus scrofa OX=9823 GN=QPCT PE=1 SV=1 CANONICAL=A0A4X1T2C1-1" }, "locus": { "chromosome": "3", "start_pos": 102822956, "end_pos": 102795649, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009293.4", "url": "https://www.ensembl.org/id/ENSSSCT00000009293.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009057.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009057.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A287AEJ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:397424", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:397424", "resource": "KEGG Pathway" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2C1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2C1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1" } ], "pmid": "" }, { "name": "glutaminyl-peptide cyclotransferase activity", "id": "GO:0016603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016603", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2C1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2C1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23652", "name": "", "equation": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "23652", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23652" } ] }, { "id": "R-SSC-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, tertiary granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6798745", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798745" } ] }, { "id": "R-SSC-6798749", "name": "Exocytosis of specific granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, specific granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6798749", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798749" } ] }, { "id": "R-SSC-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6800434" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T2C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2C1" }, { "id": "PF04389", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M28", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 352, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1TY03-1", "uniprot_ac": "A0A5K1TY03", "uniprot_id": "A0A5K1TY03_PIG", "mass": { "chemical_mass": 53690.0, "monoisotopic_mass": 53690.0 }, "refseq": {}, "gene_names": [ { "name": "SGCE", "type": "recommended", "evidence": [ { "id": "A0A5K1TY03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03" } ] } ], "protein_names": [ { "name": "Epsilon-sarcoglycan", "type": "recommended", "evidence": [ { "id": "A0A5K1TY03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AER0", "url": "https://www.uniprot.org/uniprotkb/A0A287AER0#function" }, { "database": "UniProtKB", "id": "ARBA00002860", "url": "https://www.uniprot.org/uniprotkb/ARBA00002860#function" }, { "database": "UniProtKB", "id": "A0A287AY43", "url": "https://www.uniprot.org/uniprotkb/A0A287AY43#function" }, { "database": "UniProtKB", "id": "A0A4X1TVE3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVE3#function" }, { "database": "UniProtKB", "id": "A0A5G2QC87", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC87#function" }, { "database": "UniProtKB", "id": "A0A5G2R1H3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1H3#function" }, { "database": "UniProtKB", "id": "A0A5K1TY03", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03#function" }, { "database": "UniProtKB", "id": "F1SFA5", "url": "https://www.uniprot.org/uniprotkb/F1SFA5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TY03", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SGCE", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03", "locus": { "chromosome": "9", "start_pos": 74402717, "end_pos": 74473910, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015328", "url": "https://www.ensembl.org/id/ENSSSCG00000015328" } ] } } ], "crossref": [ { "id": "A0A5K1TY03", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1TY03", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015328", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015328", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008908", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008908", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10132:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10132:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05510", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05510", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9913351", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9913351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AER0", "url": "https://www.uniprot.org/uniprotkb/A0A287AER0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AER0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AER0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AY43", "url": "https://www.uniprot.org/uniprotkb/A0A287AY43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AY43-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AY43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TVE3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TVE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QC87", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QC87-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1H3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1TY03", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1TY03-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SFA5", "url": "https://www.uniprot.org/uniprotkb/F1SFA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SFA5-1", "url": "https://www.uniprot.org/uniprotkb/F1SFA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KQLPRWWELGDPCAWTGQGRGTPRMSPATTGTFLLTAFLLSCADGINGTVNWKTKQANSFIISRKMTAGKKDVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIMPPLHADNYESTNMPLMQTQQNLPHQTQIPQPQTTGKWYP", "length": 473, "header": "tr|A0A5K1TY03-1|A0A5K1TY03_PIG Isoform 1 of Epsilon-sarcoglycan OS=Sus scrofa OX=9823 GN=SGCE PE=1 SV=1 CANONICAL=A0A5K1TY03-1" }, "isoforms": [ { "isoform_ac": "A0A287AER0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03/entry#A0A287AER0-1", "sequence": { "sequence": "KQLPRWWELGDPCAWTGQGRGTPRMSPATTGTFLLTVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIMPPLHADNYESTNMPLMQTQQNLPHQTQIPQPQTTGEY", "length": 426, "header": "tr|A0A287AER0-1|A0A5K1TY03_PIG Computationally mapped isoform of Epsilon-sarcoglycan OS=Sus scrofa OX=9823 GN=SGCE PE=1 SV=2 CANONICAL=A0A5K1TY03-1" }, "locus": { "chromosome": "9", "start_pos": 74473813, "end_pos": 74405675, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045024.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045024.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042513.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042513.2" } ] } }, { "isoform_ac": "A0A287AY43-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03/entry#A0A287AY43-1", "sequence": { "sequence": "MSPATTGTFLLTVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIMPPLHADNYESTNMPLMQTQHKMKKIKEFFKATVSYILYPRVLVKC", "length": 419, "header": "tr|A0A287AY43-1|A0A5K1TY03_PIG Computationally mapped isoform of Epsilon-sarcoglycan OS=Sus scrofa OX=9823 GN=SGCE PE=1 SV=2 CANONICAL=A0A5K1TY03-1" }, "locus": { "chromosome": "9", "start_pos": 74473741, "end_pos": 74414603, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045086.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045086.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048810.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048810.2" } ] } }, { "isoform_ac": "A0A4X1TVE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03/entry#A0A4X1TVE3-1", "sequence": { "sequence": "KQLPRWWELGDPCAWTGQGRGTPRMSPATTGTFLLTAFLLSCADGINGTVNWKTKQANSFIISRKMTAGKKDVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIMPPLHADNYESTNMPLMQTQQ", "length": 454, "header": "tr|A0A4X1TVE3-1|A0A4X1TVE3_PIG Computationally mapped isoform of Epsilon-sarcoglycan OS=Sus scrofa OX=9823 GN=SGCE PE=1 SV=1 CANONICAL=A0A5K1TY03-1" }, "locus": { "chromosome": "9", "start_pos": 74473813, "end_pos": 74403001, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091608.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091608.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074191.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074191.1" } ] } }, { "isoform_ac": "A0A5G2QC87-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03/entry#A0A5G2QC87-1", "sequence": { "sequence": "KQLPRWWELGDPCAWTGQGRGTPRMSPATTGTFLLTGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIMPPLHADNYESTNMPLMQTQQNLPHQTQIPQPQTTGDFRLTTFQRFEVNGIPEERKLTEAMNL", "length": 410, "header": "tr|A0A5G2QC87-1|A0A5G2QC87_PIG Computationally mapped isoform of Epsilon-sarcoglycan OS=Sus scrofa OX=9823 GN=SGCE PE=1 SV=1 CANONICAL=A0A5K1TY03-1" }, "locus": { "chromosome": "9", "start_pos": 74473813, "end_pos": 74402954, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072895.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072895.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059649.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059649.1" } ] } }, { "isoform_ac": "A0A5G2R1H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03/entry#A0A5G2R1H3-1", "sequence": { "sequence": "MSPATTGTFLLTAFLLSCADGINGTVNWKTKQANSFIISRKMTAGKKDVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIMPPLHADNYESTNMPLMQTQQDLFEFSASEFLGFFFCVCDLLIYQNE", "length": 456, "header": "tr|A0A5G2R1H3-1|A0A5K1TY03_PIG Computationally mapped isoform of Epsilon-sarcoglycan OS=Sus scrofa OX=9823 GN=SGCE PE=1 SV=2 CANONICAL=A0A5K1TY03-1" }, "locus": { "chromosome": "9", "start_pos": 74473741, "end_pos": 74415639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069405.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069405.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070964.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070964.2" } ] } }, { "isoform_ac": "A0A5K1TY03-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03/entry#A0A5K1TY03-1", "sequence": { "sequence": "KQLPRWWELGDPCAWTGQGRGTPRMSPATTGTFLLTAFLLSCADGINGTVNWKTKQANSFIISRKMTAGKKDVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIMPPLHADNYESTNMPLMQTQQNLPHQTQIPQPQTTGKWYP", "length": 473, "header": "tr|A0A5K1TY03-1|A0A5K1TY03_PIG Isoform 1 of Epsilon-sarcoglycan OS=Sus scrofa OX=9823 GN=SGCE PE=1 SV=1 CANONICAL=A0A5K1TY03-1" }, "locus": { "chromosome": "9", "start_pos": 74473813, "end_pos": 74402988, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029820.4", "url": "https://www.ensembl.org/id/ENSSSCT00000029820.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019710.3", "url": "https://www.ensembl.org/id/ENSSSCP00000019710.3" } ] } }, { "isoform_ac": "F1SFA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03/entry#F1SFA5-1", "sequence": { "sequence": "SKRGKKLYMYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIMPPLHADNYESTNMPLMQTQQDLFEFSASEFLGFFFCVCDLLIYQNE", "length": 416, "header": "tr|F1SFA5-1|F1SFA5_PIG Computationally mapped isoform of Epsilon-sarcoglycan OS=Sus scrofa OX=9823 GN=SGCE PE=1 SV=5 CANONICAL=A0A5K1TY03-1" }, "locus": { "chromosome": "9", "start_pos": 74447691, "end_pos": 74415639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016701.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016701.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016255.5", "url": "https://www.ensembl.org/id/ENSSSCP00000016255.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AER0", "url": "https://www.uniprot.org/uniprotkb/A0A287AER0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9913351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9913351", "resource": "Reactome", "description": "Formation of the dystrophin-glycoprotein complex (DGC)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TY03", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TY03", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TY03", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TY03", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03" } ], "pmid": "" }, { "name": "sarcoglycan complex", "id": "GO:0016012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016012", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TY03", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03" } ], "pmid": "" }, { "name": "dendrite membrane", "id": "GO:0032590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032590", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TY03", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1TY03-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 473, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1TY03-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1TY03" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1TY03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TY03" }, { "id": "SM00736", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00736" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dystroglycan-type cadherin-like", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 193, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 }, { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SIU9-1", "uniprot_ac": "A0A4X1SIU9", "uniprot_id": "A0A4X1SIU9_PIG", "mass": { "chemical_mass": 6014.0, "monoisotopic_mass": 6014.0 }, "refseq": {}, "gene_names": [ { "name": "RPS29", "type": "recommended", "evidence": [ { "id": "A0A4X1SIU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein uS14", "type": "recommended", "evidence": [ { "id": "A0A4X1SIU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S29", "type": "synonym", "evidence": [ { "id": "A0A4X1SIU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AQ67", "url": "https://www.uniprot.org/uniprotkb/A0A287AQ67#function" }, { "database": "UniProtKB", "id": "ARBA00045746", "url": "https://www.uniprot.org/uniprotkb/ARBA00045746#function" }, { "database": "UniProtKB", "id": "A0A4X1SK15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK15#function" }, { "database": "UniProtKB", "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPS29", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9", "locus": { "chromosome": "1", "start_pos": 179454928, "end_pos": 179461631, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000038507", "url": "https://www.ensembl.org/id/ENSSSCG00000038507" } ] } } ], "crossref": [ { "id": "A0A4X1SIU9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SIU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000038507", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000038507", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "414391", "url": "https://www.ncbi.nlm.nih.gov/gene/414391", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HCFREIA", "url": "https://omabrowser.org/oma/group/HCFREIA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287AQ67", "url": "https://www.orthodb.org/?gene=A0A287AQ67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12010", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12010", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12010:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12010:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12010:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12010:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AQ67", "url": "https://www.uniprot.org/uniprotkb/A0A287AQ67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AQ67-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQ67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SIU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SK15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SK15-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVFDLASVEQIFSPSGRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD", "length": 52, "header": "tr|A0A4X1SIU9-1|A0A4X1SIU9_PIG Isoform 1 of Small ribosomal subunit protein uS14 OS=Sus scrofa OX=9823 GN=RPS29 PE=3 SV=1 CANONICAL=A0A4X1SIU9-1" }, "isoforms": [ { "isoform_ac": "A0A287AQ67-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9/entry#A0A287AQ67-1", "sequence": { "sequence": "MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKVCVRGPHAPISGRGQQGVVPWCGLSANDVFCV", "length": 86, "header": "tr|A0A287AQ67-1|A0A4X1SIU9_PIG Computationally mapped isoform of Small ribosomal subunit protein uS14 OS=Sus scrofa OX=9823 GN=RPS29 PE=3 SV=1 CANONICAL=A0A4X1SIU9-1" }, "locus": { "chromosome": "1", "start_pos": 179456748, "end_pos": 179456261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099364.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099364.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078546.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078546.1" } ] } }, { "isoform_ac": "A0A4X1SIU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9/entry#A0A4X1SIU9-1", "sequence": { "sequence": "MTVFDLASVEQIFSPSGRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD", "length": 52, "header": "tr|A0A4X1SIU9-1|A0A4X1SIU9_PIG Isoform 1 of Small ribosomal subunit protein uS14 OS=Sus scrofa OX=9823 GN=RPS29 PE=3 SV=1 CANONICAL=A0A4X1SIU9-1" }, "locus": { "chromosome": "1", "start_pos": 179461631, "end_pos": 179455015, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074782.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074782.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071848.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071848.1" } ] } }, { "isoform_ac": "A0A4X1SK15-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9/entry#A0A4X1SK15-1", "sequence": { "sequence": "MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD", "length": 56, "header": "tr|A0A4X1SK15-1|A0A4X1SK15_PIG Computationally mapped isoform of Small ribosomal subunit protein uS14 OS=Sus scrofa OX=9823 GN=RPS29 PE=3 SV=1 CANONICAL=A0A4X1SIU9-1" }, "locus": { "chromosome": "1", "start_pos": 179456748, "end_pos": 179455015, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005518.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005518.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005381.2", "url": "https://www.ensembl.org/id/ENSSSCP00000005381.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AQ67", "url": "https://www.uniprot.org/uniprotkb/A0A287AQ67" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-SSC-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "P41058-1", "protein_name": "Small ribosomal subunit protein uS14B", "gene_name": "RPS29B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAHENVWFSHPRRFGKGSRQCRVCSSHTGLVRKYDLNICRQCFREKANDIGFHKYR", "length": 56 }, "evidence": [ { "id": "A0A4X1SIU9", "url": "https://omabrowser.org/oma/group/A0A4X1SIU9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P62273-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "RPS29", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD", "length": 56 }, "evidence": [ { "id": "A0A4X1SIU9", "url": "https://omabrowser.org/oma/group/A0A4X1SIU9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62274-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "Rps29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD", "length": 56 }, "evidence": [ { "id": "A0A4X1SIU9", "url": "https://omabrowser.org/oma/group/A0A4X1SIU9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P62275-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "Rps29", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD", "length": 56 }, "evidence": [ { "id": "A0A4X1SIU9", "url": "https://omabrowser.org/oma/group/A0A4X1SIU9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62276-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "RPS29", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD", "length": 56 }, "evidence": [ { "id": "A0A4X1SIU9", "url": "https://omabrowser.org/oma/group/A0A4X1SIU9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q680P8-1", "protein_name": "Small ribosomal subunit protein uS14z/uS14y/uS14x", "gene_name": "RPS29B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGHSNVWNSHPKKYGPGSRLCRVCGNSHGLIRKYGLNCCRQCFRSNAKEIGFIKYR", "length": 56 }, "evidence": [ { "id": "A0A4X1SIU9", "url": "https://omabrowser.org/oma/group/A0A4X1SIU9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q76P36-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "rps29", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARELWLTHPRNFGPGSRTCRKCGNHHGIIRKYDLNMCRRCFRTDAEAIGFNKYR", "length": 55 }, "evidence": [ { "id": "A0A4X1SIU9", "url": "https://omabrowser.org/oma/group/A0A4X1SIU9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VH69-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "RpS29", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGFATLWYSHPRKYGQGSRCCRACSNRHGLIRKYGLNICRQCFREYANDIGFKKLD", "length": 56 }, "evidence": [ { "id": "A0A4X1SIU9", "url": "https://omabrowser.org/oma/group/A0A4X1SIU9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SIU9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SIU9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1THQ0-1", "uniprot_ac": "A0A4X1THQ0", "uniprot_id": "A0A4X1THQ0_PIG", "mass": { "chemical_mass": 94071.0, "monoisotopic_mass": 94071.0 }, "refseq": { "ac": "XP_003356794", "name": "apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003356794" }, "gene_names": [ { "name": "AREL1", "type": "recommended", "evidence": [ { "id": "A0A4X1THQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0" } ] }, { "name": "AREL1", "type": "synonym", "evidence": [ { "id": "XP_003356794", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003356794" } ] } ], "protein_names": [ { "name": "Apoptosis-resistant E3 ubiquitin protein ligase 1", "type": "recommended", "evidence": [ { "id": "A0A4X1THQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.26", "type": "synonym", "evidence": [ { "id": "A0A4X1THQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0/entry#names_and_taxonomy" } ] }, { "name": "Apoptosis-resistant HECT-type E3 ubiquitin transferase 1", "type": "synonym", "evidence": [ { "id": "A0A4X1THQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0/entry#names_and_taxonomy" } ] }, { "name": "apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003356794", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003356794" } ] } ], "function": [ { "annotation": "E3 ubiquitin-protein ligase that catalyzes 'Lys-11'- or 'Lys-33'-linked polyubiquitin chains, with some preference for 'Lys-33' linkages. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates SEPTIN4, DIABLO/SMAC and HTRA2 in vitro. Modulates pulmonary inflammation by targeting SOCS2 for ubiquitination and subsequent degradation by the proteasome.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THQ0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0#function" }, { "database": "UniProtKB", "id": "ARBA00056489", "url": "https://www.uniprot.org/uniprotkb/ARBA00056489#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THQ0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AREL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0", "locus": { "chromosome": "7", "start_pos": 97875220, "end_pos": 97940876, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002370", "url": "https://www.ensembl.org/id/ENSSSCG00000002370" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002370", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002370", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100622552", "url": "https://www.ncbi.nlm.nih.gov/gene/100622552", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100622552", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622552", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287ARH6", "url": "https://www.orthodb.org/?gene=A0A287ARH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1THQ0", "url": "https://www.orthodb.org/?gene=A0A4X1THQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254:SF340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254:SF340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00630", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00630", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25915", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25915", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003356794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003356794", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287ARH6", "url": "https://www.uniprot.org/uniprotkb/A0A287ARH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ARH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ARH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1THQ0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1THQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSCKVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQEPSSNVVKVAFTVRRAGRYEISVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLTCGQPHTLQIVPRDEYDNPTNNSTSLRDEHNYSLSIHELGPQEEESAGVSFERSVTSNRQTCQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSENERNIVERNVSTSGVSIYFEAYLYNAANCASTPWHLPPMHMSSGQRRPSTALEEEDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDTNQALVHPNPNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML", "length": 823, "header": "tr|A0A4X1THQ0-1|A0A4X1THQ0_PIG Isoform 1 of Apoptosis-resistant E3 ubiquitin protein ligase 1 OS=Sus scrofa OX=9823 GN=AREL1 PE=4 SV=1 CANONICAL=A0A4X1THQ0-1" }, "isoforms": [ { "isoform_ac": "A0A287ARH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0/entry#A0A287ARH6-1", "sequence": { "sequence": "MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSCKVSWDWKDPYELFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQEPSSNVVKVAFTVRRAGRYEISVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLTCGQPHTLQIVPRDEYDNPTNNSTSLRDEHNYSLSIHELGPQEEESAGVSFERSVTSNRQTCQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSENERNIVERNVSTSGVSIYFEAYLYNAANCASTPWHLPPMHMSSGQRRPSTALEEEDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDTNQALVHPNPNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML", "length": 813, "header": "tr|A0A287ARH6-1|A0A4X1THQ0_PIG Computationally mapped isoform of Apoptosis-resistant E3 ubiquitin protein ligase 1 OS=Sus scrofa OX=9823 GN=AREL1 PE=4 SV=3 CANONICAL=A0A4X1THQ0-1" }, "locus": { "chromosome": "7", "start_pos": 97919610, "end_pos": 97896054, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045456.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045456.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046685.3", "url": "https://www.ensembl.org/id/ENSSSCP00000046685.3" } ] } }, { "isoform_ac": "A0A4X1THQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0/entry#A0A4X1THQ0-1", "sequence": { "sequence": "MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSCKVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQEPSSNVVKVAFTVRRAGRYEISVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLTCGQPHTLQIVPRDEYDNPTNNSTSLRDEHNYSLSIHELGPQEEESAGVSFERSVTSNRQTCQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSENERNIVERNVSTSGVSIYFEAYLYNAANCASTPWHLPPMHMSSGQRRPSTALEEEDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDTNQALVHPNPNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML", "length": 823, "header": "tr|A0A4X1THQ0-1|A0A4X1THQ0_PIG Isoform 1 of Apoptosis-resistant E3 ubiquitin protein ligase 1 OS=Sus scrofa OX=9823 GN=AREL1 PE=4 SV=1 CANONICAL=A0A4X1THQ0-1" }, "locus": { "chromosome": "7", "start_pos": 97919610, "end_pos": 97896054, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057866.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057866.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051436.1", "url": "https://www.ensembl.org/id/ENSSSCP00000051436.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ARH6", "url": "https://www.uniprot.org/uniprotkb/A0A287ARH6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100622552", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622552", "resource": "KEGG Pathway" }, { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THQ0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THQ0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THQ0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THQ0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THQ0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THQ0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THQ0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THQ0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0" } ], "pmid": "" }, { "name": "protein K33-linked ubiquitination", "id": "GO:1990390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990390", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THQ0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983140" } ] }, { "id": "R-SSC-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983147" } ] }, { "id": "R-SSC-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983156" } ] }, { "id": "R-SSC-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1THQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THQ0" }, { "id": "PS50237", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50237" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HECT", "eco_id": "ECO_0000259", "start_pos": 483, "end_pos": 823, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 210, "end_pos": 212 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 631, "end_pos": 633 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RND3-1", "uniprot_ac": "A0A5G2RND3", "uniprot_id": "A0A5G2RND3_PIG", "mass": { "chemical_mass": 49841.0, "monoisotopic_mass": 49841.0 }, "refseq": {}, "gene_names": [ { "name": "SEPTIN8", "type": "recommended", "evidence": [ { "id": "A0A5G2RND3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ] } ], "protein_names": [ { "name": "Septin", "type": "recommended", "evidence": [ { "id": "A0A5G2RND3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Filament-forming cytoskeletal GTPase.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FQ67", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQ67#function" }, { "database": "UniProtKB", "id": "PIRNR006698", "url": "https://www.uniprot.org/uniprotkb/PIRNR006698#function" }, { "database": "UniProtKB", "id": "A0A287AWW1", "url": "https://www.uniprot.org/uniprotkb/A0A287AWW1#function" }, { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SEPTIN8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3", "locus": { "chromosome": "2", "start_pos": 135077170, "end_pos": 135104471, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014285", "url": "https://www.ensembl.org/id/ENSSSCG00000014285" } ] } } ], "crossref": [ { "id": "A0A5G2RND3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RND3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014285", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014285", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01850", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01850", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523954", "url": "https://www.ncbi.nlm.nih.gov/gene/100523954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A287AWW1", "url": "https://www.orthodb.org/?gene=A0A287AWW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AWW1", "url": "https://www.uniprot.org/uniprotkb/A0A287AWW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AWW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AWW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RND3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQ67", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQ67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQ67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQ67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RJU9", "url": "https://www.uniprot.org/uniprotkb/F1RJU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RJU9-1", "url": "https://www.uniprot.org/uniprotkb/F1RJU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEECVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEELGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETSAFNRRKAAVEALQSQALHATSQQPLRKDKDKKK", "length": 429, "header": "tr|A0A5G2RND3-1|A0A5G2RND3_PIG Isoform 1 of Septin OS=Sus scrofa OX=9823 GN=SEPTIN8 PE=1 SV=1 CANONICAL=A0A5G2RND3-1" }, "isoforms": [ { "isoform_ac": "A0A287AWW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3/entry#A0A287AWW1-1", "sequence": { "sequence": "MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEECVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEELGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETSAFNRRKAAVEALQSQALHATSQQPLRKDKDKKKSEIGAQQSGMSLSSSKVMMTKASVEPLNCSSWWPAIQCCSCLVRDATWREGFL", "length": 482, "header": "tr|A0A287AWW1-1|A0A5G2RND3_PIG Computationally mapped isoform of Septin OS=Sus scrofa OX=9823 GN=SEPTIN8 PE=1 SV=3 CANONICAL=A0A5G2RND3-1" }, "locus": { "chromosome": "2", "start_pos": 135104240, "end_pos": 135078316, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053612.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053612.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048379.3", "url": "https://www.ensembl.org/id/ENSSSCP00000048379.3" } ] } }, { "isoform_ac": "A0A5G2QWZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3/entry#A0A5G2QWZ4-1", "sequence": { "sequence": "MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEECVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEELGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETSAFNRRKAAVEALQSQALHVVGSWPWARDDDQGQCGALELQQLVARHTVLQLPGQGRDVEGRIPLRQQLLHVGPAQDHQGVELETVVFKIRSERPILFRYQGPKVQTI", "length": 503, "header": "tr|A0A5G2QWZ4-1|A0A5G2RND3_PIG Computationally mapped isoform of Septin OS=Sus scrofa OX=9823 GN=SEPTIN8 PE=1 SV=2 CANONICAL=A0A5G2RND3-1" }, "locus": { "chromosome": "2", "start_pos": 135104240, "end_pos": 135078185, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076173.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076173.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069391.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069391.2" } ] } }, { "isoform_ac": "A0A5G2RND3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3/entry#A0A5G2RND3-1", "sequence": { "sequence": "MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEECVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEELGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETSAFNRRKAAVEALQSQALHATSQQPLRKDKDKKK", "length": 429, "header": "tr|A0A5G2RND3-1|A0A5G2RND3_PIG Isoform 1 of Septin OS=Sus scrofa OX=9823 GN=SEPTIN8 PE=1 SV=1 CANONICAL=A0A5G2RND3-1" }, "locus": { "chromosome": "2", "start_pos": 135104240, "end_pos": 135087949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091077.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091077.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074335.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074335.1" } ] } }, { "isoform_ac": "A0A8W4FQ67-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3/entry#A0A8W4FQ67-1", "sequence": { "sequence": "FDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEECVRLRPQTYDLQESNVQLKLTIVDAVGEGVSHRYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEELGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETSAFNRRKAAVEALQSQALHATSQQPLRKDKDKKK", "length": 399, "header": "tr|A0A8W4FQ67-1|A0A5G2RND3_PIG Computationally mapped isoform of Septin OS=Sus scrofa OX=9823 GN=SEPTIN8 PE=1 SV=1 CANONICAL=A0A5G2RND3-1" }, "locus": { "chromosome": "2", "start_pos": 135093101, "end_pos": 135087949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099343.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099343.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080491.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080491.1" } ] } }, { "isoform_ac": "F1RJU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3/entry#F1RJU9-1", "sequence": { "sequence": "MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEECVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEELGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETSAFNRRKAAVEALQSQALHATSQQPLRKDKDKKKSLFAFSWRSHRTKRRRCLMFVNNVRKKLPAEELFPFSCPLREPIPGPHMLLCSCWFASH", "length": 488, "header": "tr|F1RJU9-1|A0A5G2RND3_PIG Computationally mapped isoform of Septin OS=Sus scrofa OX=9823 GN=SEPTIN8 PE=1 SV=5 CANONICAL=A0A5G2RND3-1" }, "locus": { "chromosome": "2", "start_pos": 135104240, "end_pos": 135083913, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015608.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015608.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015196.5", "url": "https://www.ensembl.org/id/ENSSSCP00000015196.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FQ67", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQ67" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ], "pmid": "" }, { "name": "septin ring", "id": "GO:0005940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005940", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ], "pmid": "" }, { "name": "septin complex", "id": "GO:0031105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031105", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ], "pmid": "" }, { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RND3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RND3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 429, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RND3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RND3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RND3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RND3" }, { "id": "PS51719", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51719" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Septin-type G", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 307, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T854-1", "uniprot_ac": "A0A4X1T854", "uniprot_id": "A0A4X1T854_PIG", "mass": { "chemical_mass": 105678.0, "monoisotopic_mass": 105678.0 }, "refseq": { "ac": "NP_001230112", "name": "AP-2 complex subunit beta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230112" }, "gene_names": [ { "name": "AP2B1", "type": "recommended", "evidence": [ { "id": "A0A4X1T854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ] }, { "name": "AP2B1", "type": "synonym", "evidence": [ { "id": "NP_001230112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230112" } ] } ], "protein_names": [ { "name": "AP complex subunit beta", "type": "recommended", "evidence": [ { "id": "A0A4X1T854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854/entry#names_and_taxonomy" } ] }, { "name": "AP-2 complex subunit beta", "type": "synonym", "evidence": [ { "id": "NP_001230112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230112" } ] }, { "name": "adaptor related protein complex 2 beta 1 subunit", "type": "synonym", "evidence": [ { "id": "NP_001230112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230112" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AP2B1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854", "locus": { "chromosome": "12", "start_pos": 39800972, "end_pos": 39932643, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017712", "url": "https://www.ensembl.org/id/ENSSSCG00000017712" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017712", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017712", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100620457", "url": "https://www.ncbi.nlm.nih.gov/gene/100620457", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012295", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012295", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013037", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013037", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100620457", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620457", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PECNEWG", "url": "https://omabrowser.org/oma/group/PECNEWG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T854", "url": "https://www.orthodb.org/?gene=A0A4X1T854", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02883", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02883", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2132295", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-416993", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416993", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-437239", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-437239", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5099900", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5099900", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5140745", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5140745", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8866427", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8866427", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8964038", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964038", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230112", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230112", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AZ79", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AZ79-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480V5W1", "url": "https://www.uniprot.org/uniprotkb/A0A480V5W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480V5W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A480V5W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T854-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1GFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GFC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1GFC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GFC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D2CII4", "url": "https://www.uniprot.org/uniprotkb/A0A8D2CII4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D2CII4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D2CII4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPNDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN", "length": 951, "header": "tr|A0A4X1T854-1|A0A4X1T854_PIG Isoform 1 of AP complex subunit beta OS=Sus scrofa OX=9823 GN=AP2B1 PE=1 SV=1 CANONICAL=A0A4X1T854-1" }, "isoforms": [ { "isoform_ac": "A0A287AZ79-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854/entry#A0A287AZ79-1", "sequence": { "sequence": "MLGVWFSGPGTSPICSLLGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPNDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVSNFLYSFFCFFFLILFILKLGVGLYLIPVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMGKYFLLSFCQIDLCPSSEDTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTVRCLRPQISKTISQLRSPQLPP", "length": 904, "header": "tr|A0A287AZ79-1|A0A4X1T854_PIG Computationally mapped isoform of AP complex subunit beta OS=Sus scrofa OX=9823 GN=AP2B1 PE=1 SV=3 CANONICAL=A0A4X1T854-1" }, "locus": { "chromosome": "12", "start_pos": 39914506, "end_pos": 39808458, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051689.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051689.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049269.3", "url": "https://www.ensembl.org/id/ENSSSCP00000049269.3" } ] } }, { "isoform_ac": "A0A480V5W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854/entry#A0A480V5W1-1", "sequence": { "sequence": "MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPNDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN", "length": 937, "header": "tr|A0A480V5W1-1|A0A480V5W1_PIG Computationally mapped isoform of AP complex subunit beta OS=Sus scrofa OX=9823 GN=AP2B1 PE=1 SV=1 CANONICAL=A0A4X1T854-1" }, "locus": { "chromosome": "12", "start_pos": 39918380, "end_pos": 39803467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044337.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044337.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059316.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059316.2" } ] } }, { "isoform_ac": "A0A4X1T854-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854/entry#A0A4X1T854-1", "sequence": { "sequence": "MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPNDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN", "length": 951, "header": "tr|A0A4X1T854-1|A0A4X1T854_PIG Isoform 1 of AP complex subunit beta OS=Sus scrofa OX=9823 GN=AP2B1 PE=1 SV=1 CANONICAL=A0A4X1T854-1" }, "locus": { "chromosome": "12", "start_pos": 39918380, "end_pos": 39803467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058297.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058297.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047385.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047385.2" } ] } }, { "isoform_ac": "A0A8D1GFC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854/entry#A0A8D1GFC4-1", "sequence": { "sequence": "MLGVWFSGPGTSPICSLLGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPNDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN", "length": 943, "header": "tr|A0A8D1GFC4-1|A0A4X1T854_PIG Computationally mapped isoform of AP complex subunit beta OS=Sus scrofa OX=9823 GN=AP2B1 PE=1 SV=1 CANONICAL=A0A4X1T854-1" }, "locus": { "chromosome": "12", "start_pos": 39914506, "end_pos": 39803467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025334.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025334.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019788.4", "url": "https://www.ensembl.org/id/ENSSSCP00000019788.4" } ] } }, { "isoform_ac": "A0A8D2CII4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854/entry#A0A8D2CII4-1", "sequence": { "sequence": "MLGVWFSGPGTSPICSLLGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPNDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSAGSPPTFPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMGKYFLLAKTNSFLVYLSATLEGLIDLGCSTSA", "length": 868, "header": "tr|A0A8D2CII4-1|A0A4X1T854_PIG Computationally mapped isoform of AP complex subunit beta OS=Sus scrofa OX=9823 GN=AP2B1 PE=1 SV=1 CANONICAL=A0A4X1T854-1" }, "locus": { "chromosome": "12", "start_pos": 39914506, "end_pos": 39816064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076849.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076849.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073065.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073065.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 696, "start_aa": "Thr", "end_pos": 696, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr696", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1GFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GFC4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100620457", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620457", "resource": "KEGG Pathway" }, { "id": "R-SSC-2132295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "resource": "Reactome", "description": "MHC class II antigen presentation" }, { "id": "R-SSC-416993", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416993", "resource": "Reactome", "description": "Trafficking of GluR2-containing AMPA receptors" }, { "id": "R-SSC-437239", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-437239", "resource": "Reactome", "description": "Recycling pathway of L1" }, { "id": "R-SSC-5099900", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5099900", "resource": "Reactome", "description": "WNT5A-dependent internalization of FZD4" }, { "id": "R-SSC-5140745", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5140745", "resource": "Reactome", "description": "WNT5A-dependent internalization of FZD2, FZD5 and ROR2" }, { "id": "R-SSC-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-SSC-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" }, { "id": "R-SSC-8866427", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8866427", "resource": "Reactome", "description": "VLDLR internalisation and degradation" }, { "id": "R-SSC-8964038", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964038", "resource": "Reactome", "description": "LDL clearance" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061HW92-1", "protein_name": "AP complex subunit beta", "gene_name": "Ap2b1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN", "length": 951 }, "evidence": [ { "id": "A0A4X1T854", "url": "https://omabrowser.org/oma/group/A0A4X1T854/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P62944-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "Ap2b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN", "length": 937 }, "evidence": [ { "id": "A0A4X1T854", "url": "https://omabrowser.org/oma/group/A0A4X1T854/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN", "length": 937 }, "evidence": [ { "id": "A0A4X1T854", "url": "https://omabrowser.org/oma/group/A0A4X1T854/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q08DS7-1", "protein_name": "AP-1 complex subunit beta-1", "gene_name": "AP2B1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKESDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN", "length": 951 }, "evidence": [ { "id": "A0A4X1T854", "url": "https://omabrowser.org/oma/group/A0A4X1T854/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9DBG3-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "Ap2b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTTTNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN", "length": 937 }, "evidence": [ { "id": "A0A4X1T854", "url": "https://omabrowser.org/oma/group/A0A4X1T854/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" }, { "name": "postsynaptic neurotransmitter receptor internalization", "id": "GO:0098884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098884", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" }, { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" }, { "name": "clathrin adaptor complex", "id": "GO:0030131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030131", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" }, { "name": "AP-2 adaptor complex", "id": "GO:0030122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030122", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" }, { "name": "membrane coat", "id": "GO:0030117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030117", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T854", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 755, "end_pos": 757, "annotation": "n_glycosylation_sequon" }, { "start_pos": 793, "end_pos": 795, "annotation": "n_glycosylation_sequon" }, { "start_pos": 925, "end_pos": 927, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" }, { "id": "SM01020", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-adaptin appendage C-terminal subdomain", "eco_id": "ECO_0000259", "start_pos": 840, "end_pos": 950, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T854" }, { "id": "SM00809", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00809" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain", "eco_id": "ECO_0000259", "start_pos": 721, "end_pos": 831, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 696 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 272, "end_pos": 274 }, { "start_pos": 755, "end_pos": 757 }, { "start_pos": 793, "end_pos": 795 }, { "start_pos": 925, "end_pos": 927 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5S6FW47-1", "uniprot_ac": "A0A5S6FW47", "uniprot_id": "A0A5S6FW47_PIG", "mass": { "chemical_mass": 9205.0, "monoisotopic_mass": 9205.0 }, "refseq": {}, "gene_names": [ { "name": "HCST", "type": "recommended", "evidence": [ { "id": "A0A5S6FW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47" } ] } ], "protein_names": [ { "name": "Hematopoietic cell signal transducer", "type": "recommended", "evidence": [ { "id": "A0A5S6FW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47/entry#names_and_taxonomy" } ] }, { "name": "DNAX-activation protein 10", "type": "synonym", "evidence": [ { "id": "A0A5S6FW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47/entry#names_and_taxonomy" } ] }, { "name": "Membrane protein DAP10", "type": "synonym", "evidence": [ { "id": "A0A5S6FW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5S6FW47", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HCST", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47", "locus": {} } ], "crossref": [ { "id": "A0A5S6FW47", "url": "https://alphafold.ebi.ac.uk/entry/A0A5S6FW47", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002918", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002918", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR009861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21409:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21409:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07213", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07213", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B894", "url": "https://www.uniprot.org/uniprotkb/A0A287B894", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B894-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B894-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5S6FW47", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5S6FW47-1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPGGILFLLLLPVAAAQVTSGEKSTPLSLCGAATSGSCSGCGPLSLPLLAGLVAADAVVSLLIVVGVFVCGRPRSRPTQDGKIYINMPGRG", "length": 93, "header": "tr|A0A5S6FW47-1|A0A5S6FW47_PIG Isoform 1 of Hematopoietic cell signal transducer OS=Sus scrofa OX=9823 GN=HCST PE=3 SV=2 CANONICAL=A0A5S6FW47-1" }, "isoforms": [ { "isoform_ac": "A0A287B894-1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47/entry#A0A287B894-1", "sequence": { "sequence": "EINTPFPLWSSDFRYCFPPPAAPKCGLTFLEHPQRLSRSPSDLPSPNRRLQRTHSPLWNSISPFSSPNRRPRDPATPPPEAYLQGYPPCPEHSPWGLGTHQPVSGSPLIPQGIWATQLQRDLLCPKPSHECLEPHPPRQPPSHLGPNPSGSCSGCGPLSLPLLAGLVAADAVVSLLIVVGVFVCGRPRSRPTQGEGRDGLGLKRVGVPREGGPQGGGPRASPGGSGETLGAVLGGTPEETPETGGPQGSGDVGGRWVVRPRALSPPPPEDGKIYINMPGRG", "length": 281, "header": "tr|A0A287B894-1|A0A5S6FW47_PIG Computationally mapped isoform of Hematopoietic cell signal transducer OS=Sus scrofa OX=9823 GN=HCST PE=3 SV=2 CANONICAL=A0A5S6FW47-1" }, "locus": { "chromosome": "6", "start_pos": 45308928, "end_pos": 45308086, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040952.2", "url": "https://www.ensembl.org/id/ENSSSCT00000040952.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052528.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052528.2" } ] } }, { "isoform_ac": "A0A5G2QMU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47/entry#A0A5G2QMU2-1", "sequence": { "sequence": "EINTPFPLWSSDFRYCFPPPAAPKCGLTFLEHPQRLSRSPSDLPSPNRRLQRTHSPLWNSISPFSSPNRRPRDPATPPPEAYLQGYPPCPEHSPWGLGTHQPVSGSPLIPQGIWATQLQRDLLCPKPSHECLEPHPPRQPPSHLGPNPSGSCSGCGPLSLPLLAGLVAADAVVSLLIVVGVFVCGRPRSRPTQEDGKIYINMPGRG", "length": 206, "header": "tr|A0A5G2QMU2-1|A0A5G2QMU2_PIG Computationally mapped isoform of Hematopoietic cell signal transducer OS=Sus scrofa OX=9823 GN=HCST PE=3 SV=1 CANONICAL=A0A5S6FW47-1" }, "locus": { "chromosome": "6", "start_pos": 45308928, "end_pos": 45308086, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075597.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075597.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063438.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063438.1" } ] } }, { "isoform_ac": "A0A5S6FW47-1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47/entry#A0A5S6FW47-1", "sequence": { "sequence": "MAPPGGILFLLLLPVAAAQVTSGEKSTPLSLCGAATSGSCSGCGPLSLPLLAGLVAADAVVSLLIVVGVFVCGRPRSRPTQDGKIYINMPGRG", "length": 93, "header": "tr|A0A5S6FW47-1|A0A5S6FW47_PIG Isoform 1 of Hematopoietic cell signal transducer OS=Sus scrofa OX=9823 GN=HCST PE=3 SV=2 CANONICAL=A0A5S6FW47-1" }, "locus": { "chromosome": "6", "start_pos": 45308928, "end_pos": 45307634, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003223.4", "url": "https://www.ensembl.org/id/ENSSSCT00000003223.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003142.3", "url": "https://www.ensembl.org/id/ENSSSCP00000003142.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B894", "url": "https://www.uniprot.org/uniprotkb/A0A287B894" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6FW47", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase binding", "id": "GO:0043548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043548", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6FW47", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6FW47", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6FW47", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47" } ], "pmid": "" }, { "name": "regulation of immune response", "id": "GO:0050776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050776", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6FW47", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FW47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5S6FW47-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 93, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5S6FW47-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5S6FW47" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TP96-1", "uniprot_ac": "A0A4X1TP96", "uniprot_id": "A0A4X1TP96_PIG", "mass": { "chemical_mass": 107128.0, "monoisotopic_mass": 107128.0 }, "refseq": {}, "gene_names": [ { "name": "EIF4G2", "type": "recommended", "evidence": [ { "id": "A0A4X1TP96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 4 gamma 2", "type": "recommended", "evidence": [ { "id": "A0A4X1TP96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BKE1", "url": "https://www.uniprot.org/uniprotkb/A0A287BKE1#function" }, { "database": "UniProtKB", "id": "ARBA00037759", "url": "https://www.uniprot.org/uniprotkb/ARBA00037759#function" }, { "database": "UniProtKB", "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96#function" }, { "database": "UniProtKB", "id": "A0A5G2R4S5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S5#function" }, { "database": "UniProtKB", "id": "A0A5G2R593", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R593#function" }, { "database": "UniProtKB", "id": "A0A5G2RLT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EIF4G2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96", "locus": { "chromosome": "2", "start_pos": 48678950, "end_pos": 48666520, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013405", "url": "https://www.ensembl.org/id/ENSSSCG00000013405" } ] } } ], "crossref": [ { "id": "A0A4X1TP96", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TP96", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013405", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013405", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11559", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11559", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CAPLDIN", "url": "https://omabrowser.org/oma/group/CAPLDIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23253:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23253:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1169408", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1169408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BKE1", "url": "https://www.uniprot.org/uniprotkb/A0A287BKE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BKE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BKE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TP96-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4S5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R593", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R593", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R593-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R593-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVVSNFGTLFSFQVFRFSHPFPPHPSINIILLKILRCQAAKVESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "length": 949, "header": "tr|A0A4X1TP96-1|A0A4X1TP96_PIG Isoform 1 of Eukaryotic translation initiation factor 4 gamma 2 OS=Sus scrofa OX=9823 GN=EIF4G2 PE=1 SV=1 CANONICAL=A0A4X1TP96-1" }, "isoforms": [ { "isoform_ac": "A0A287BKE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96/entry#A0A287BKE1-1", "sequence": { "sequence": "VESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "length": 869, "header": "tr|A0A287BKE1-1|A0A4X1TP96_PIG Computationally mapped isoform of Eukaryotic translation initiation factor 4 gamma 2 OS=Sus scrofa OX=9823 GN=EIF4G2 PE=1 SV=2 CANONICAL=A0A4X1TP96-1" }, "locus": { "chromosome": "2", "start_pos": 48677890, "end_pos": 48668175, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044271.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044271.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056542.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056542.2" } ] } }, { "isoform_ac": "A0A4X1TP96-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96/entry#A0A4X1TP96-1", "sequence": { "sequence": "MLVVSNFGTLFSFQVFRFSHPFPPHPSINIILLKILRCQAAKVESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "length": 949, "header": "tr|A0A4X1TP96-1|A0A4X1TP96_PIG Isoform 1 of Eukaryotic translation initiation factor 4 gamma 2 OS=Sus scrofa OX=9823 GN=EIF4G2 PE=1 SV=1 CANONICAL=A0A4X1TP96-1" }, "locus": { "chromosome": "2", "start_pos": 48677890, "end_pos": 48668049, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014645.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014645.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014250.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014250.3" } ] } }, { "isoform_ac": "A0A5G2R4S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96/entry#A0A5G2R4S5-1", "sequence": { "sequence": "MTTPQQTTPQMKKNDMMQSSGNFSTSILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "length": 850, "header": "tr|A0A5G2R4S5-1|A0A4X1TP96_PIG Computationally mapped isoform of Eukaryotic translation initiation factor 4 gamma 2 OS=Sus scrofa OX=9823 GN=EIF4G2 PE=1 SV=1 CANONICAL=A0A4X1TP96-1" }, "locus": { "chromosome": "2", "start_pos": 48677890, "end_pos": 48669314, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091140.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091140.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069190.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069190.1" } ] } }, { "isoform_ac": "A0A5G2R593-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96/entry#A0A5G2R593-1", "sequence": { "sequence": "VESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "length": 907, "header": "tr|A0A5G2R593-1|A0A4X1TP96_PIG Computationally mapped isoform of Eukaryotic translation initiation factor 4 gamma 2 OS=Sus scrofa OX=9823 GN=EIF4G2 PE=1 SV=1 CANONICAL=A0A4X1TP96-1" }, "locus": { "chromosome": "2", "start_pos": 48677890, "end_pos": 48668175, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069106.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069106.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071489.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071489.1" } ] } }, { "isoform_ac": "A0A5G2RLT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96/entry#A0A5G2RLT1-1", "sequence": { "sequence": "MEVAASIGWWLQQRPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQWNSSPREELICQGIPQCALNTWRVI", "length": 900, "header": "tr|A0A5G2RLT1-1|A0A5G2RLT1_PIG Computationally mapped isoform of Eukaryotic translation initiation factor 4 gamma 2 OS=Sus scrofa OX=9823 GN=EIF4G2 PE=1 SV=2 CANONICAL=A0A4X1TP96-1" }, "locus": { "chromosome": "2", "start_pos": 48677230, "end_pos": 48666539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067562.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067562.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073369.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073369.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BKE1", "url": "https://www.uniprot.org/uniprotkb/A0A287BKE1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1169408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1169408", "resource": "Reactome", "description": "ISG15 antiviral mechanism" } ], "orthologs": [ { "uniprot_canonical_ac": "F2Z4C6-1", "protein_name": "Eukaryotic translation initiation factor 4 gamma 2", "gene_name": "EIF4G2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVAILRCQAAKVESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "length": 919 }, "evidence": [ { "id": "A0A4X1TP96", "url": "https://omabrowser.org/oma/group/A0A4X1TP96/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P78344-1", "protein_name": "Eukaryotic translation initiation factor 4 gamma 2", "gene_name": "EIF4G2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "length": 907 }, "evidence": [ { "id": "A0A4X1TP96", "url": "https://omabrowser.org/oma/group/A0A4X1TP96/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62448-1", "protein_name": "Eukaryotic translation initiation factor 4 gamma 2", "gene_name": "Eif4g2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTEAVVTDYLNSGNANDAVSGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLEQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVSPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSSFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "length": 906 }, "evidence": [ { "id": "A0A4X1TP96", "url": "https://omabrowser.org/oma/group/A0A4X1TP96/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" } ], "pmid": "" }, { "name": "translation factor activity, RNA binding", "id": "GO:0008135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008135", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 4F complex", "id": "GO:0016281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016281", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP96", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 799, "end_pos": 801, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TP96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" }, { "id": "PS51366", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51366" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MI", "eco_id": "ECO_0000259", "start_pos": 585, "end_pos": 708, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TP96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP96" }, { "id": "PS51363", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51363" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "W2", "eco_id": "ECO_0000259", "start_pos": 762, "end_pos": 946, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 799, "end_pos": 801 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RMP4-1", "uniprot_ac": "A0A5G2RMP4", "uniprot_id": "A0A5G2RMP4_PIG", "mass": { "chemical_mass": 57230.0, "monoisotopic_mass": 57230.0 }, "refseq": {}, "gene_names": [ { "name": "CYP2J35", "type": "recommended", "evidence": [ { "id": "A0A5G2RMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4" } ] } ], "protein_names": [ { "name": "Cytochrome P450 2J2", "type": "recommended", "evidence": [ { "id": "A0A5G2RMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CYP2J35", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4", "locus": {} } ], "crossref": [ { "id": "A0A5G2RMP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RMP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003825", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003825", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20662", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20662", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300:SF177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300:SF177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287BPQ5", "url": "https://www.uniprot.org/uniprotkb/A0A287BPQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BPQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BPQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QGW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QGW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGAVGFLAEVFGTALGPSALLLSAVAFLFVADILKRWRPKNYPPGPLRLPFVGNFLHLDFEQWHLSLQRFVKKYGNVLSLDLGAFSSVVITGLPLIKEALVHQDQNFVNRPINLNQVFQKNGLIMSNGQVWKEQRRFALTTLRNFGLGKKSLEERIQEEAQYLIQAVREENGQPFDPHFKINNAVSNIICSITFGERFDYQDDQFQELLRLLDEVTCLPKSVRVQLFNVFPRIMKLLPGPHQIIFSNREKLRMFIARVIENHRRDWNPAEARDFIDAYLREIEKVRKPDSPSVFNEENLICSTLDLFFAGTETTSTTLRWGLLYMALYPEVQEKVQAEIDRVLGQSQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVAVDTTLAGYHLPKGTTVLINLTALHRDPAEWATPDTFNPEHFLENGKFKKREAFLPFSIGKRACLGEQLARTELFVFFTSLLQKFSFRPPDNEKLSLKFRVGLTLSPVTSRICAVPRA", "length": 501, "header": "tr|A0A5G2RMP4-1|A0A5G2RMP4_PIG Isoform 1 of Cytochrome P450 2J2 OS=Sus scrofa OX=9823 GN=CYP2J35 PE=3 SV=2 CANONICAL=A0A5G2RMP4-1" }, "isoforms": [ { "isoform_ac": "A0A287BPQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4/entry#A0A287BPQ5-1", "sequence": { "sequence": "LVRAQCGGGRRRVLGRVGGAGSSESETHRGHWLAHSTEEQADVSAMLGAVGFLAEVFGTALGPSALLLSAVAFLFVADILKRWRPKNYPPGPLRLPFVGNFLHLDFEQWHLSLQRFVKKYGNVLSLDLGAFSSVVITGLPLIKEALVHQDQNFVNRPINLNQVFQKNGLIMSNGQVWKEQRRFALTTLRNFGLGKKSLEERIQEEAQYLIQAVREENGQPFDPHFKINNAVSNIICSITFGERFDYQDDQFQELLRLLDEVTCLPKSVRVQLFNVFPRIMKLLPGPHQIIFSNREKLRMFIARVIENHRRDWNPAEARDFIDAYLREIEKVRKPDSPSVFNEENLICSTLDLFFAGTETTSTTLRWGLLYMALYPEVQEKVQAEIDRVLGQSQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVAVDTTLAGYHLPKGTTVLINLTALHRDPAEWATPDTFNPEHFLENGKFKKREAFLPFSIGKRACLGEQLARTELFVFFTSLLQKFSFRPPDNEKLSLKFRVGLTLSPVTSRICAVPRA", "length": 546, "header": "tr|A0A287BPQ5-1|A0A5G2RMP4_PIG Computationally mapped isoform of Cytochrome P450 2J2 OS=Sus scrofa OX=9823 GN=CYP2J35 PE=3 SV=3 CANONICAL=A0A5G2RMP4-1" }, "locus": { "chromosome": "6", "start_pos": 152530532, "end_pos": 152506566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061616.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061616.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058081.3", "url": "https://www.ensembl.org/id/ENSSSCP00000058081.3" } ] } }, { "isoform_ac": "A0A5G2QGW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4/entry#A0A5G2QGW1-1", "sequence": { "sequence": "MLGAVGFLAEVFGTALGPSALLLSAVAFLFVADILKRWRPKNYPPGPLRLPFVGNFLHLDFEQWHLSLQRFVKKYGNVLSLDLGAFSSVVITGLPLIKEALVHQDQNFVNRPINLNQVFQKNGLIMSNGQVWKEQRRFALTTLRNFGLGKKSLEERIQEEAQYLIQAVREENGQPFDPHFKINNAVSNIICSITFGERFDYQDDQFQELLRLLDEPTGTTLLCLLFNVFPRIMKLLPGPHQIIFSNREKLRMFIARVIENHRRDWNPAEARDFIDAYLREIEKGSSPSVFNEENLICSTLDLFFAGTETTSTTLRWGLLYMALYPEVQEKVQAEIDRVLGQSQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVAVDTTLAGYHLPKGTTVLINLTALHRDPAEWATPDTFNPEHFLENGKFKKREAFLPFSIGKRACLGEQLARTELFVFFTSLLQKFSFRPPDNEKLSLKFRVGLTLSPVTSRICAVPRA", "length": 496, "header": "tr|A0A5G2QGW1-1|A0A5G2QGW1_PIG Computationally mapped isoform of Cytochrome P450 2J2 OS=Sus scrofa OX=9823 GN=CYP2J35 PE=3 SV=2 CANONICAL=A0A5G2RMP4-1" }, "locus": { "chromosome": "6", "start_pos": 152530532, "end_pos": 152506791, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078721.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078721.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063048.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063048.2" } ] } }, { "isoform_ac": "A0A5G2RMP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4/entry#A0A5G2RMP4-1", "sequence": { "sequence": "MLGAVGFLAEVFGTALGPSALLLSAVAFLFVADILKRWRPKNYPPGPLRLPFVGNFLHLDFEQWHLSLQRFVKKYGNVLSLDLGAFSSVVITGLPLIKEALVHQDQNFVNRPINLNQVFQKNGLIMSNGQVWKEQRRFALTTLRNFGLGKKSLEERIQEEAQYLIQAVREENGQPFDPHFKINNAVSNIICSITFGERFDYQDDQFQELLRLLDEVTCLPKSVRVQLFNVFPRIMKLLPGPHQIIFSNREKLRMFIARVIENHRRDWNPAEARDFIDAYLREIEKVRKPDSPSVFNEENLICSTLDLFFAGTETTSTTLRWGLLYMALYPEVQEKVQAEIDRVLGQSQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVAVDTTLAGYHLPKGTTVLINLTALHRDPAEWATPDTFNPEHFLENGKFKKREAFLPFSIGKRACLGEQLARTELFVFFTSLLQKFSFRPPDNEKLSLKFRVGLTLSPVTSRICAVPRA", "length": 501, "header": "tr|A0A5G2RMP4-1|A0A5G2RMP4_PIG Isoform 1 of Cytochrome P450 2J2 OS=Sus scrofa OX=9823 GN=CYP2J35 PE=3 SV=2 CANONICAL=A0A5G2RMP4-1" }, "locus": { "chromosome": "6", "start_pos": 152530532, "end_pos": 152506791, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089244.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089244.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073904.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073904.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BPQ5", "url": "https://www.uniprot.org/uniprotkb/A0A287BPQ5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4" } ], "pmid": "" }, { "name": "organic acid metabolic process", "id": "GO:0006082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006082", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RMP4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 501, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RMP4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RMP4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 403, "end_pos": 405 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SYN3-1", "uniprot_ac": "A0A4X1SYN3", "uniprot_id": "A0A4X1SYN3_PIG", "mass": { "chemical_mass": 70960.0, "monoisotopic_mass": 70960.0 }, "refseq": { "ac": "XP_003130898", "name": "zinc finger MYND domain-containing protein 11 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130898" }, "gene_names": [ { "name": "ZMYND11", "type": "recommended", "evidence": [ { "id": "A0A4X1SYN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ] }, { "name": "ZMYND11", "type": "synonym", "evidence": [ { "id": "XP_003130898", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130898" } ] } ], "protein_names": [ { "name": "Zinc finger MYND domain-containing protein 11", "type": "recommended", "evidence": [ { "id": "A0A4X1SYN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3/entry#names_and_taxonomy" } ] }, { "name": "zinc finger MYND domain-containing protein 11 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_003130898", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130898" } ] } ], "function": [ { "annotation": "Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3#function" }, { "database": "UniProtKB", "id": "ARBA00057630", "url": "https://www.uniprot.org/uniprotkb/ARBA00057630#function" }, { "database": "UniProtKB", "id": "A0A287B977", "url": "https://www.uniprot.org/uniprotkb/A0A287B977#function" }, { "database": "UniProtKB", "id": "A0A480U735", "url": "https://www.uniprot.org/uniprotkb/A0A480U735#function" }, { "database": "UniProtKB", "id": "A0A8W4F8H7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8H7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZMYND11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3", "locus": { "chromosome": "10", "start_pos": 69159455, "end_pos": 69295306, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011166", "url": "https://www.ensembl.org/id/ENSSSCG00000011166" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011166", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011166", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05492", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05492", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15537", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15537", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20159", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20159", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523014", "url": "https://www.ncbi.nlm.nih.gov/gene/100523014", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523014", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523014", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QCHRVYH", "url": "https://omabrowser.org/oma/group/QCHRVYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A480U735", "url": "https://www.orthodb.org/?gene=A0A480U735", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SYN3", "url": "https://www.orthodb.org/?gene=A0A4X1SYN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8W4F8H7", "url": "https://www.orthodb.org/?gene=A0A8W4F8H7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1RX42", "url": "https://www.orthodb.org/?gene=F1RX42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46379:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46379:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21524", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21524", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23461", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23461", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003130898", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130898", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B977", "url": "https://www.uniprot.org/uniprotkb/A0A287B977", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B977-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B977-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLS5", "url": "https://www.uniprot.org/uniprotkb/A0A287BLS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BLS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BM07", "url": "https://www.uniprot.org/uniprotkb/A0A287BM07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BM07-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BM07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480U735", "url": "https://www.uniprot.org/uniprotkb/A0A480U735", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480U735-1", "url": "https://www.uniprot.org/uniprotkb/A0A480U735-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SYN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SYW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SYW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0MYT6", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MYT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0MYT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MYT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1RG88", "url": "https://www.uniprot.org/uniprotkb/A0A8D1RG88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1RG88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1RG88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8H7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8H7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RX42", "url": "https://www.uniprot.org/uniprotkb/F1RX42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RX42-1", "url": "https://www.uniprot.org/uniprotkb/F1RX42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEYRLRDSSSHWQCPVCRSIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSLCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 602, "header": "tr|A0A4X1SYN3-1|A0A4X1SYN3_PIG Isoform 1 of Zinc finger MYND domain-containing protein 11 OS=Sus scrofa OX=9823 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A4X1SYN3-1" }, "isoforms": [ { "isoform_ac": "A0A287B977-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3/entry#A0A287B977-1", "sequence": { "sequence": "YMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEYRLRDSSSHWQCPVCRSIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSLCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 563, "header": "tr|A0A287B977-1|A0A287B977_PIG Computationally mapped isoform of Zinc finger MYND domain-containing protein 11 OS=Sus scrofa OX=9823 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A4X1SYN3-1" }, "locus": { "chromosome": "10", "start_pos": 69212952, "end_pos": 69161632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060375.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060375.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053076.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053076.2" } ] } }, { "isoform_ac": "A0A287BLS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3/entry#A0A287BLS5-1", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEISIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHEIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSLCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 522, "header": "tr|A0A287BLS5-1|A0A287BLS5_PIG Computationally mapped isoform of Zinc finger MYND-type containing 11 OS=Sus scrofa OX=9823 GN=ZMYND11 PE=4 SV=3 CANONICAL=A0A4X1SYN3-1" }, "locus": { "chromosome": "10", "start_pos": 69235167, "end_pos": 69161632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042795.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042795.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057565.3", "url": "https://www.ensembl.org/id/ENSSSCP00000057565.3" } ] } }, { "isoform_ac": "A0A287BM07-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3/entry#A0A287BM07-1", "sequence": { "sequence": "MKCMCGSVRICSSLGRGAEHRTEGSIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSLCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 480, "header": "tr|A0A287BM07-1|A0A287BM07_PIG Computationally mapped isoform of Zinc finger MYND-type containing 11 OS=Sus scrofa OX=9823 GN=ZMYND11 PE=4 SV=3 CANONICAL=A0A4X1SYN3-1" }, "locus": { "chromosome": "10", "start_pos": 69295167, "end_pos": 69161632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050900.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050900.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057453.3", "url": "https://www.ensembl.org/id/ENSSSCP00000057453.3" } ] } }, { "isoform_ac": "A0A480U735-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3/entry#A0A480U735-1", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIAYSMQPFSRTAAPNKDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEYRLRDSSSHWQCPVCRSIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSLCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 617, "header": "tr|A0A480U735-1|A0A4X1SYN3_PIG Computationally mapped isoform of Zinc finger MYND domain-containing protein 11 OS=Sus scrofa OX=9823 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A4X1SYN3-1" }, "locus": { "chromosome": "10", "start_pos": 69235167, "end_pos": 69161632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099682.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099682.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075889.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075889.1" } ] } }, { "isoform_ac": "A0A4X1SYN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3/entry#A0A4X1SYN3-1", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEYRLRDSSSHWQCPVCRSIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSLCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 602, "header": "tr|A0A4X1SYN3-1|A0A4X1SYN3_PIG Isoform 1 of Zinc finger MYND domain-containing protein 11 OS=Sus scrofa OX=9823 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A4X1SYN3-1" }, "locus": { "chromosome": "10", "start_pos": 69235167, "end_pos": 69161632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054778.2", "url": "https://www.ensembl.org/id/ENSSSCT00000054778.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042458.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042458.1" } ] } }, { "isoform_ac": "A0A4X1SYW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3/entry#A0A4X1SYW1-1", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEYRLRDSSSHWQCPVCRSIKKKNTNKQEMSTYLRFIVSRMKERKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSLCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 571, "header": "tr|A0A4X1SYW1-1|A0A4X1SYW1_PIG Computationally mapped isoform of Zinc finger MYND-type containing 11 OS=Sus scrofa OX=9823 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A4X1SYN3-1" }, "locus": { "chromosome": "10", "start_pos": 69235167, "end_pos": 69161632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058751.2", "url": "https://www.ensembl.org/id/ENSSSCT00000058751.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045471.2", "url": "https://www.ensembl.org/id/ENSSSCP00000045471.2" } ] } }, { "isoform_ac": "A0A8D0MYT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3/entry#A0A8D0MYT6-1", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIAYSMQPFSRTAAPNKDWETENHDWLRDSSSHWQCPVCRSIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSLCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 586, "header": "tr|A0A8D0MYT6-1|A0A4X1SYN3_PIG Computationally mapped isoform of Zinc finger MYND domain-containing protein 11 OS=Sus scrofa OX=9823 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A4X1SYN3-1" }, "locus": { "chromosome": "10", "start_pos": 69235167, "end_pos": 69161632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087917.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087917.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068866.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068866.1" } ] } }, { "isoform_ac": "A0A8D1RG88-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3/entry#A0A8D1RG88-1", "sequence": { "sequence": "MSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEISIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSLCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 508, "header": "tr|A0A8D1RG88-1|A0A4X1SYN3_PIG Computationally mapped isoform of Zinc finger MYND domain-containing protein 11 OS=Sus scrofa OX=9823 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A4X1SYN3-1" }, "locus": { "chromosome": "10", "start_pos": 69212949, "end_pos": 69161632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105071.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105071.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075295.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075295.1" } ] } }, { "isoform_ac": "A0A8W4F8H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3/entry#A0A8W4F8H7-1", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEYRLRDSSSHWQCPVCRSIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGDSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSLCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 601, "header": "tr|A0A8W4F8H7-1|A0A4X1SYN3_PIG Computationally mapped isoform of Zinc finger MYND domain-containing protein 11 OS=Sus scrofa OX=9823 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A4X1SYN3-1" }, "locus": { "chromosome": "10", "start_pos": 69235167, "end_pos": 69161632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097570.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097570.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075120.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075120.1" } ] } }, { "isoform_ac": "F1RX42-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3/entry#F1RX42-1", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEISIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSLCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 548, "header": "tr|F1RX42-1|A0A4X1SYN3_PIG Computationally mapped isoform of Zinc finger MYND domain-containing protein 11 OS=Sus scrofa OX=9823 GN=ZMYND11 PE=4 SV=2 CANONICAL=A0A4X1SYN3-1" }, "locus": { "chromosome": "10", "start_pos": 69235167, "end_pos": 69161632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012228.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012228.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011914.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011914.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0MYT6", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MYT6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523014", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523014", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PNL6-1", "protein_name": "Zinc finger MYND domain-containing protein 11", "gene_name": "ZMYND11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSHWQCPVCRSIKKKNTSKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDKGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSMELKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPKMLHRSTQTNNDGVCQNMCHDKYTKIFNDFKDRMKADHKRETERVVREAVEKLRTEMEEEKRQAVSKAVANAQGEMDRKCKQVKEKCKEEFLEEIKKLAGQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 602 }, "evidence": [ { "id": "A0A4X1SYN3", "url": "https://omabrowser.org/oma/group/A0A4X1SYN3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q1LJL9-1", "protein_name": "Zinc finger MYND domain-containing protein 11", "gene_name": "ZMYND11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEYRLRDSSSHWQCPVCRSIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 602 }, "evidence": [ { "id": "A0A4X1SYN3", "url": "https://omabrowser.org/oma/group/A0A4X1SYN3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7FKH2-1", "protein_name": "Zinc finger MYND domain-containing protein 11", "gene_name": "Zmynd11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETETHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSHWQCPVCRSIKKKHSNKQEMGTYLRFIVSRMKERAIDLNKKGKDSKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKATQEPRAKKGRRNQSVEPKKEVSCPPHSVQVAVERGKSLKVRSRQSSNIRQVKAQSPDSCRCGLLLDQHASAQSPSPEPEPETEAVSSSQEIPTMPQPIERVSVSTQTKKLSASSPRMLHRSTQTASDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLAAQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 658 }, "evidence": [ { "id": "A0A4X1SYN3", "url": "https://omabrowser.org/oma/group/A0A4X1SYN3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15326-1", "protein_name": "Zinc finger MYND domain-containing protein 11", "gene_name": "ZMYND11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSPWQCPVCRSIKKKNTNKQEMGTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 602 }, "evidence": [ { "id": "A0A4X1SYN3", "url": "https://omabrowser.org/oma/group/A0A4X1SYN3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R5C8-1", "protein_name": "Zinc finger MYND domain-containing protein 11", "gene_name": "Zmynd11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETETHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSHWQCPVCRSIKKKHSNKQEMGTYLRFIVSRMKERAIDLNKKGKDSKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIERVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVASLQGDMDRKGKQLKEKCKEEFVEEIKKLAAQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 602 }, "evidence": [ { "id": "A0A4X1SYN3", "url": "https://omabrowser.org/oma/group/A0A4X1SYN3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001237", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "negative regulation of JNK cascade", "id": "GO:0046329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046329", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "histone H3K36me3 reader activity", "id": "GO:0140003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140003", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" }, { "name": "histone H3 reader activity", "id": "GO:0140006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140006", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SYN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 186, "end_pos": 238, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SYN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" }, { "id": "PS50865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYND-type", "eco_id": "ECO_0000259", "start_pos": 563, "end_pos": 598, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SYN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 148, "start_aa": "Asp", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SYN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" }, { "id": "PS50812", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50812" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWWP", "eco_id": "ECO_0000259", "start_pos": 280, "end_pos": 331, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SYN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYN3" }, { "id": "PS52014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAMD1-like winged helix (WH)", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 82, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 401, "end_pos": 403 }, { "start_pos": 577, "end_pos": 579 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SX53-1", "uniprot_ac": "A0A4X1SX53", "uniprot_id": "A0A4X1SX53_PIG", "mass": { "chemical_mass": 15217.0, "monoisotopic_mass": 15217.0 }, "refseq": { "ac": "XP_003126911", "name": "transmembrane protein 170A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126911" }, "gene_names": [ { "name": "TMEM170A", "type": "recommended", "evidence": [ { "id": "A0A4X1SX53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53" } ] }, { "name": "TMEM170A", "type": "synonym", "evidence": [ { "id": "XP_003126911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126911" } ] } ], "protein_names": [ { "name": "Transmembrane protein 170A", "type": "recommended", "evidence": [ { "id": "A0A4X1SX53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 170A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003126911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126911" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX53", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMEM170A", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53", "locus": { "chromosome": "6", "start_pos": 12215744, "end_pos": 12195137, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000028464", "url": "https://www.ensembl.org/id/ENSSSCG00000028464" } ] } } ], "crossref": [ { "id": "A0A4X1SX53", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SX53", "database": "AlphaFoldDB", "categories": [] }, { "id": "100522740", "url": "https://www.ncbi.nlm.nih.gov/gene/100522740", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522740", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522740", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GRFMSVG", "url": "https://omabrowser.org/oma/group/GRFMSVG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SX53", "url": "https://www.orthodb.org/?gene=A0A4X1SX53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22779", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22779", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22779:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22779:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10190", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10190", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003126911", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126911", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SV32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SV32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SV32-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SV32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SX53", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SX53-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHEGSGGSGGSAGLLQQILSLKLVPRVGNGTLCPNSTSLCSFPEMWYGVFLWALVSSLFFHVPAGLLALFTLRHHKYGRFMSVSILLMGIVGPITAGVLTSAAIAGVYRAAGKEMIPFEALTLGTGQTFCVVVVSFLRILATL", "length": 144, "header": "tr|A0A4X1SX53-1|A0A4X1SX53_PIG Isoform 1 of Transmembrane protein 170A OS=Sus scrofa OX=9823 GN=TMEM170A PE=3 SV=1 CANONICAL=A0A4X1SX53-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SV32-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53/entry#A0A4X1SV32-1", "sequence": { "sequence": "MEHEGSGGSGGSAGLLQQILSLKLVPRVGNGTLCPNSTSLCSFPEMWYGVFLWALVSSLFFHVPAGLLALFTLRHHKYGRFMSVSILLMGIVGPITAGVLTSMSAINIVNVS", "length": 112, "header": "tr|A0A4X1SV32-1|A0A4X1SV32_PIG Computationally mapped isoform of Transmembrane protein 170A OS=Sus scrofa OX=9823 GN=TMEM170A PE=3 SV=1 CANONICAL=A0A4X1SX53-1" }, "locus": { "chromosome": "6", "start_pos": 12208677, "end_pos": 12195283, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070110.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070110.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074433.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074433.1" } ] } }, { "isoform_ac": "A0A4X1SX53-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53/entry#A0A4X1SX53-1", "sequence": { "sequence": "MEHEGSGGSGGSAGLLQQILSLKLVPRVGNGTLCPNSTSLCSFPEMWYGVFLWALVSSLFFHVPAGLLALFTLRHHKYGRFMSVSILLMGIVGPITAGVLTSAAIAGVYRAAGKEMIPFEALTLGTGQTFCVVVVSFLRILATL", "length": 144, "header": "tr|A0A4X1SX53-1|A0A4X1SX53_PIG Isoform 1 of Transmembrane protein 170A OS=Sus scrofa OX=9823 GN=TMEM170A PE=3 SV=1 CANONICAL=A0A4X1SX53-1" }, "locus": { "chromosome": "6", "start_pos": 12211979, "end_pos": 12195283, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049854.2", "url": "https://www.ensembl.org/id/ENSSSCT00000049854.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050977.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050977.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX53", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522740", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522740", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A3KPL7-1", "protein_name": "Transmembrane protein 170A", "gene_name": "tmem170a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIEALIVGEMQDVQIGFVKQILSLNLVPRSNNTTCGNNTSLCDFSEMWYGVFLWAVVSSLIFHLPAALLALATLRRHKVARFFPLGILLMGIIGPLFGGVLTSAAIAGVYKAAGKSMFSLEALVFGVGQSLFIFIISFLRILATL", "length": 145 }, "evidence": [ { "id": "A0A4X1SX53", "url": "https://omabrowser.org/oma/group/A0A4X1SX53/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8WVE7-1", "protein_name": "Transmembrane protein 170A", "gene_name": "TMEM170A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEREGSGGSGGSAGLLQQILSLKVVPRVGNGTLCPNSTSLCSFPEMWYGVFLWALVSSLFFHVPAGLLALFTLRHHKYGRFMSVSILLMGIVGPITAGILTSAAIAGVYRAAGKEMIPFEALTLGTGQTFCVLVVSFLRILATL", "length": 144 }, "evidence": [ { "id": "A0A4X1SX53", "url": "https://omabrowser.org/oma/group/A0A4X1SX53/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D342-1", "protein_name": "Transmembrane protein 170A", "gene_name": "Tmem170a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEREGSGGGGGSAGLLQQILSLKLVPRVGNGTLCPNSTSLCSFPEMWYGVFLWALMSSVFFHVPAGLLALFTLRHHKYGRFMSVSILLMGIVGPITAGILTSAAIAGVYRAAGKEMIPFEALTLGTGQTFCVVVVSFLRVLATL", "length": 144 }, "evidence": [ { "id": "A0A4X1SX53", "url": "https://omabrowser.org/oma/group/A0A4X1SX53/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX53", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX53", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum tubular network organization", "id": "GO:0071786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071786", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX53", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53" } ], "pmid": "" }, { "name": "nuclear envelope organization", "id": "GO:0006998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006998", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX53", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53" } ], "pmid": "" }, { "name": "nuclear pore complex assembly", "id": "GO:0051292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051292", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX53", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX53" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 }, { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T800-1", "uniprot_ac": "A0A4X1T800", "uniprot_id": "A0A4X1T800_PIG", "mass": { "chemical_mass": 48616.0, "monoisotopic_mass": 48616.0 }, "refseq": { "ac": "XP_001928086", "name": "steroid hormone receptor ERR2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928086" }, "gene_names": [ { "name": "ESRRB", "type": "recommended", "evidence": [ { "id": "A0A4X1T800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ] }, { "name": "ESRRB", "type": "synonym", "evidence": [ { "id": "XP_001928086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928086" } ] } ], "protein_names": [ { "name": "Estrogen related receptor beta", "type": "synonym", "evidence": [ { "id": "A0A4X1T800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800/entry#names_and_taxonomy" } ] }, { "name": "steroid hormone receptor ERR2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_001928086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928086" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ESRRB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800", "locus": { "chromosome": "7", "start_pos": 99699011, "end_pos": 99514168, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002388", "url": "https://www.ensembl.org/id/ENSSSCG00000002388" } ] } } ], "crossref": [ { "id": "A0A4X1T800", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T800", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002388", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002388", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06946", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06946", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100151940", "url": "https://www.ncbi.nlm.nih.gov/gene/100151940", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027289", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027289", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100151940", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151940", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNGVRRD", "url": "https://omabrowser.org/oma/group/WNGVRRD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T800", "url": "https://www.orthodb.org/?gene=A0A4X1T800", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001928086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928086", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T800-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2P9", "url": "https://www.uniprot.org/uniprotkb/F1S2P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2P9-1", "url": "https://www.uniprot.org/uniprotkb/F1S2P9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLNRMSADDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGAHANGLDSPPMFAGAGLGGTPCRKGYEDCASGLMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSNLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPRRTGKLLLTLPLLRQTAAKAVQHFYSIKLQGKVPMHKLFLEMLEAKV", "length": 438, "header": "tr|A0A4X1T800-1|A0A4X1T800_PIG Isoform 1 of Estrogen related receptor beta OS=Sus scrofa OX=9823 GN=ESRRB PE=3 SV=1 CANONICAL=A0A4X1T800-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T800-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800/entry#A0A4X1T800-1", "sequence": { "sequence": "MLLNRMSADDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGAHANGLDSPPMFAGAGLGGTPCRKGYEDCASGLMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSNLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPRRTGKLLLTLPLLRQTAAKAVQHFYSIKLQGKVPMHKLFLEMLEAKV", "length": 438, "header": "tr|A0A4X1T800-1|A0A4X1T800_PIG Isoform 1 of Estrogen related receptor beta OS=Sus scrofa OX=9823 GN=ESRRB PE=3 SV=1 CANONICAL=A0A4X1T800-1" }, "locus": { "chromosome": "7", "start_pos": 99696187, "end_pos": 99514299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066216.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066216.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049178.1", "url": "https://www.ensembl.org/id/ENSSSCP00000049178.1" } ] } }, { "isoform_ac": "F1S2P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800/entry#F1S2P9-1", "sequence": { "sequence": "MDVSELCIPDPLGYHNQLLNRMSADDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGAHANGLDSPPMFAGAGLGGTPCRKGYEDCASGLMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSNLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPRRTGKLLLTLPLLRQTAAKAVQHFYSIKLQGKVPMHKLFLEMLEAKV", "length": 454, "header": "tr|F1S2P9-1|A0A4X1T800_PIG Computationally mapped isoform of Estrogen related receptor beta OS=Sus scrofa OX=9823 GN=ESRRB PE=3 SV=3 CANONICAL=A0A4X1T800-1" }, "locus": { "chromosome": "7", "start_pos": 99696187, "end_pos": 99581146, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002655.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002655.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002588.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002588.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2P9", "url": "https://www.uniprot.org/uniprotkb/F1S2P9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100151940", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151940", "resource": "KEGG Pathway" }, { "id": "R-SSC-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PDM1-1", "protein_name": "Estrogen related receptor beta", "gene_name": "ESRRB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLLGRMATEERHLSSSCGSFIKTEPSSPSSGIDAISHHSPSGSSDASGGYGIAMGGHPNGLDSPPMFNGTGIGGGSCRKRYDDCASAIMEDSPTKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSTYLSLQIPPPAKKPLTKIVSHLLVAEPEKIYAMPDPTMPESDIKALTTLCDLADRELVVIIGWAKHIPGFSNLSLGDQMSLLQSAWMEILILGIVYRSLPYEDKLVYAEDYIMDEEHSRLTGLLELYLAILQLVRRYKKLKVEKEEFVTLKALALANSDSMHIEDMDAVQKLQDLLHEALQDYELSQRNEEPRRAGKLLLTLPLLRQTAAKAVQHFYSIKLQGKVPMHKLFLEMLEAKV", "length": 438 }, "evidence": [ { "id": "A0A4X1T800", "url": "https://omabrowser.org/oma/group/A0A4X1T800/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q1M3W3-1", "protein_name": "Estrogen related receptor beta", "gene_name": "ESRRB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDVSELCVPDPLGYHNQLLNRMSADDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGAHANGLDSPPMFAGAGLGGTPCRKGYEDCAGGLMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSNLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPRRTGKLLLTLPLLRQTAAKAVQHFYSIKLQGKVPMHKLFLEMLEAKV", "length": 454 }, "evidence": [ { "id": "A0A4X1T800", "url": "https://omabrowser.org/oma/group/A0A4X1T800/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P11475-1", "protein_name": "Steroid hormone receptor ERR2", "gene_name": "Esrrb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSEDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGMALGTHANGLDSPPMFAGAGLGGNPCRKSYEDCTSGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSENSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPDDVPEGDIKALTTLCDLADRELVFLISWAKHIPGFSNLTLGDQMSLLQSAWMEILILGIVYRSLPYDDKLAYAEDYIMDEEHSRLVGLLELYRAILQLVRRYKKLKVEKEEFVMLKALALANSDSMYIENLEAVQKLQDLLHEALQDYELSQRHEEPRRAGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV", "length": 433 }, "evidence": [ { "id": "A0A4X1T800", "url": "https://omabrowser.org/oma/group/A0A4X1T800/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61539-1", "protein_name": "Steroid hormone receptor ERR2", "gene_name": "Esrrb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSEDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGIALSTHANGLDSPPMFAGAGLGGNPCRKSYEDCTSGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYNCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSENSPYLNLPISPPAKKPLTKIVSNLLGVEQDKLYAMPPNDIPEGDIKALTTLCELADRELVFLINWAKHIPGFPSLTLGDQMSLLQSAWMEILILGIVYRSLPYDDKLAYAEDYIMDEEHSRLVGLLDLYRAILQLVRRYKKLKVEKEEFMILKALALANSDSMYIENLEAVQKLQDLLHEALQDYELSQRHEEPRRAGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV", "length": 433 }, "evidence": [ { "id": "A0A4X1T800", "url": "https://omabrowser.org/oma/group/A0A4X1T800/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "estrogen response element binding", "id": "GO:0034056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034056", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ], "pmid": "" }, { "name": "nuclear steroid receptor activity", "id": "GO:0003707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003707", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ], "pmid": "" }, { "name": "steroid binding", "id": "GO:0005496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005496", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T800", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" }, { "id": "PS51843", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51843" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NR LBD", "eco_id": "ECO_0000259", "start_pos": 213, "end_pos": 437, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T800" }, { "id": "PS51030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nuclear receptor", "eco_id": "ECO_0000259", "start_pos": 105, "end_pos": 180, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T1R0-1", "uniprot_ac": "A0A4X1T1R0", "uniprot_id": "A0A4X1T1R0_PIG", "mass": { "chemical_mass": 30359.0, "monoisotopic_mass": 30359.0 }, "refseq": { "ac": "XP_003125285", "name": "G patch domain-containing protein 11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125285" }, "gene_names": [ { "name": "GPATCH11", "type": "recommended", "evidence": [ { "id": "A0A4X1T1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0" } ] }, { "name": "GPATCH11", "type": "synonym", "evidence": [ { "id": "XP_003125285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125285" } ] } ], "protein_names": [ { "name": "G patch domain-containing protein 11", "type": "recommended", "evidence": [ { "id": "A0A4X1T1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 75", "type": "synonym", "evidence": [ { "id": "A0A4X1T1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0/entry#names_and_taxonomy" } ] }, { "name": "G patch domain-containing protein 11", "type": "synonym", "evidence": [ { "id": "XP_003125285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125285" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GPATCH11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0", "locus": { "chromosome": "3", "start_pos": 103098588, "end_pos": 103119512, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008497", "url": "https://www.ensembl.org/id/ENSSSCG00000008497" } ] } } ], "crossref": [ { "id": "ENSSSCG00000008497", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008497", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100523901", "url": "https://www.ncbi.nlm.nih.gov/gene/100523901", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523901", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523901", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DYMNMVI", "url": "https://omabrowser.org/oma/group/DYMNMVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T1R0", "url": "https://www.orthodb.org/?gene=A0A4X1T1R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21032", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21032", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21032:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21032:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13821", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13821", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003125285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125285", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T1R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4P2", "url": "https://www.uniprot.org/uniprotkb/F1S4P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4P2-1", "url": "https://www.uniprot.org/uniprotkb/F1S4P2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLNMAEEEDYMSDAFINVQEDIRPGLPMLRQIREAHRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGDGIVEPIPLSVKTGKSGIGHETFLKRKAEEKLESYRRKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDTQKNIQVPREAWYWLSPEEETEEEEEEDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTAYEDKEDLSSNCPGPTSADHD", "length": 260, "header": "tr|A0A4X1T1R0-1|A0A4X1T1R0_PIG Isoform 1 of G patch domain-containing protein 11 OS=Sus scrofa OX=9823 GN=GPATCH11 PE=3 SV=1 CANONICAL=A0A4X1T1R0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T1R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0/entry#A0A4X1T1R0-1", "sequence": { "sequence": "MRLNMAEEEDYMSDAFINVQEDIRPGLPMLRQIREAHRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGDGIVEPIPLSVKTGKSGIGHETFLKRKAEEKLESYRRKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDTQKNIQVPREAWYWLSPEEETEEEEEEDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTAYEDKEDLSSNCPGPTSADHD", "length": 260, "header": "tr|A0A4X1T1R0-1|A0A4X1T1R0_PIG Isoform 1 of G patch domain-containing protein 11 OS=Sus scrofa OX=9823 GN=GPATCH11 PE=3 SV=1 CANONICAL=A0A4X1T1R0-1" }, "locus": { "chromosome": "3", "start_pos": 103107521, "end_pos": 103100136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074828.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074828.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060887.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060887.1" } ] } }, { "isoform_ac": "F1S4P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0/entry#F1S4P2-1", "sequence": { "sequence": "LRGSRSCQLTSGEAARYFCHMRLNMAEEEDYMSDAFINVQEDIRPGLPMLRQIREAHRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGDGIVEPIPLSVKTGKSGIGHETFLKRKAEEKLESYRRKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDTQKNIQVPREAWYWLSPEEETEEEEEEDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTAYEDKEDLSSNCPGPTSADHD", "length": 280, "header": "tr|F1S4P2-1|A0A4X1T1R0_PIG Computationally mapped isoform of G patch domain-containing protein 11 OS=Sus scrofa OX=9823 GN=GPATCH11 PE=3 SV=4 CANONICAL=A0A4X1T1R0-1" }, "locus": { "chromosome": "3", "start_pos": 103111890, "end_pos": 103100136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009299.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009299.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009063.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009063.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 255, "start_aa": "Thr", "end_pos": 255, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr255", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S4P2", "url": "https://www.uniprot.org/uniprotkb/F1S4P2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523901", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523901", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y0L0-1", "protein_name": "G patch domain-containing protein 11", "gene_name": "GPATCH11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGDEEEEDYMSDLFIKEDVRPGVPMVRRVREALQKEEKQKEANEKNRQKSVKEEEKERRDLVLSSALGNENKGFALLLKMGYKSGQALGKSGEGIVEPIPLNIKTGRSGLGHEEFKKRKAEEKLENYRQKLHMKKQANEQAADQFRIRFKNKQEERKMEGDLRKSQRACQQLDIQKDIEAPKEIWYWLQPEEEDQKDEEKDDECTGSDLSVSAKLQILTAYLREEHFYCIWCGTTFEDAEDLSSNCPGDSAADHD", "length": 255 }, "evidence": [ { "id": "A0A4X1T1R0", "url": "https://omabrowser.org/oma/group/A0A4X1T1R0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1LV52-1", "protein_name": "G patch domain-containing protein 11", "gene_name": "Gpatch11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RKENMAEEEDYMSDSFINVQEDVRPGVPMLRQIREARRKEEKQQQANLKNRQKSLKEEERERRDIGLKNALGCENKGFALLQKMGYKSGQALGKTGDGIVEPIPLNVKTGKSGIGHESLLKRKAEERLESYRRKIHMKNQREEKAAEEFRMRLKSKQDELRLEGDLRRSQRACQQLDAQKNIQVPREAWYWMRPEEETEEEEEEKEEQDEDKCPSEDLSVLEKLQILTGYLREEHLYCIWCGTAYEDKEDLSSNCPGPTSADHD", "length": 264 }, "evidence": [ { "id": "A0A4X1T1R0", "url": "https://omabrowser.org/oma/group/A0A4X1T1R0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q06152-1", "protein_name": "Uncharacterized protein YLR271W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEESKTKRKEDRIDLKNTPPQKKSKRDSTNDETARTSLRSIMPRGYKMMENMGYKEGETLGSNESALKEPIKVEINTKRRGIRAEKPDPSTMNDMQMSEQRFIKRESEMKNNKRLKKIWYRIQKVAFEMMGDSDLYNPGEDPRDFNVLWRSYVMQLNEEVAKNDLNNHSNNDNEDKNNMIPMVNESLEASPAIKGEKFGRPSTLIDCDTSIIGSRITKDTELAELEELSIEKRITKLNIFLRSEKYYCFFCGIKYKDEGDLYEHCPGVNEDDHK", "length": 274 }, "evidence": [ { "id": "A0A4X1T1R0", "url": "https://omabrowser.org/oma/group/A0A4X1T1R0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2KI19-1", "protein_name": "G patch domain-containing protein 11", "gene_name": "GPATCH11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKRQEANLKNRQKSIKEEEQERRDMGLKNALGCENKGFALLQKMGYKSGQALGKSGDGIVEPIPLNVKTGKSGIGHETLLKRKAEEKLESYRRKIHMKSQAEERAAEQFRIRLKNKQDEMKLEGDLRRSQRACQQLDTQKNIQVPREAWYWLRPEEETEEETEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTAYEDKEDLSSNCPGPTSADHD", "length": 260 }, "evidence": [ { "id": "A0A4X1T1R0", "url": "https://omabrowser.org/oma/group/A0A4X1T1R0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UFS4-1", "protein_name": "G patch domain-containing protein 11", "gene_name": "Gpatch11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEEEDYMSDSFINVQEDVRPGVPMLRQIREARRKEEKQQQANLRNRQKSVKEEERERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGDGIVEPIPLNVKTGKSGIGHESSLKRKAEERLENYRRKIHMKNQNEAKAAEEFRMRLKSKQDEMRLEGDLRRSQRACQQLDAQKNIQVPREAWYWLRPEEETEEEEEEEEKEEQDEDECPSEDLSVLEKLQILTGYLREEHLYCIWCGTAYEDKEDLSSNCPGPTSADHD", "length": 262 }, "evidence": [ { "id": "A0A4X1T1R0", "url": "https://omabrowser.org/oma/group/A0A4X1T1R0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N954-1", "protein_name": "G patch domain-containing protein 11", "gene_name": "GPATCH11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSARSTALNRGEQRAVRYYSHMKLNMAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTAYEDKEDLSSNCPGPTSADHD", "length": 285 }, "evidence": [ { "id": "A0A4X1T1R0", "url": "https://omabrowser.org/oma/group/A0A4X1T1R0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M2Q7-1", "protein_name": "D111/G-patch domain-containing protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAESTRNLTGLGGEAAKEEDDEYMGDLSQFIPQELSQTSKRKESEKKTVIVEPSRKKLKNLNWHERRRLEKERKQIEEDEQTLARIVDTPIGESNIGFKLLKQMGYKPGSALGKQGSGRAEPVTMDIRRSRAGVGREDPHKEKKKKEEIEAENEKRKVDEMLEDFGSRQKSQWRKKRVLINFRKAKAALDQLENVEVVPEKKNEEDEDGKPDEEEEEEEEITEEDLQEILMKLRAEHWYCLFCGFQYETTEALLSNCPGVNEDDH", "length": 265 }, "evidence": [ { "id": "A0A4X1T1R0", "url": "https://omabrowser.org/oma/group/A0A4X1T1R0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VI83-1", "protein_name": "G patch domain-containing protein 11", "gene_name": "Dmel\\CG10053", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDEEEDYMSDKFLVGLQDVRPSLVHNRGRKRQIEVESKKDELKKRQRETAASSGNVDNVRLQQSLNKPISADNKGFQLLAKMGYKAGSGLGITSDARTEPVGITIKSGRGGLGREAAVAELALKRQKLRRAHLLNKAGIKSDEEVSTEAYRRRATHKAEERKLQYDIKRCQQTCESLDLKSAITEPDLDFFWPPKPKDEDESQSDADDPEVEVPPKQEPYSPSEQLELLTGYLRTAYCFCYWCGTHYDDAEDLGSNCPGLTRDEH", "length": 266 }, "evidence": [ { "id": "A0A4X1T1R0", "url": "https://omabrowser.org/oma/group/A0A4X1T1R0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1R0" }, { "id": "PS50174", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-patch", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 119, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 255 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RJE7-1", "uniprot_ac": "A0A5G2RJE7", "uniprot_id": "A0A5G2RJE7_PIG", "mass": { "chemical_mass": 40112.0, "monoisotopic_mass": 40112.0 }, "refseq": {}, "gene_names": [ { "name": "EMC10", "type": "recommended", "evidence": [ { "id": "A0A5G2RJE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7" } ] } ], "protein_names": [ { "name": "ER membrane protein complex subunit 10", "type": "recommended", "evidence": [ { "id": "A0A5G2RJE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EMC10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7", "locus": { "chromosome": "6", "start_pos": 55322249, "end_pos": 55316468, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000039372", "url": "https://www.ensembl.org/id/ENSSSCG00000039372" } ] } } ], "crossref": [ { "id": "A0A5G2RJE7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RJE7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000039372", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000039372", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22209", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22209", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100526111", "url": "https://www.ncbi.nlm.nih.gov/gene/100526111", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "A0A286ZQ46", "url": "https://www.orthodb.org/?gene=A0A286ZQ46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21397", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21397", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21397:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21397:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21203", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21203", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZQ46", "url": "https://www.uniprot.org/uniprotkb/A0A286ZQ46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZQ46-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZQ46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B147", "url": "https://www.uniprot.org/uniprotkb/A0A287B147", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B147-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B147-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGARAGATRLLLLLVMAAAAPSRARGSGCRSGASVRGAGAESREGEGCGTVGLLLEHSFEIDDSAHFRKRGSLLWNQQDGTLSLSQRQLNEEERGRLRDVAALNGVYRVRVPRRPGAPDGPESGGYVSSFVPACSLLESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLELFNTSVQLQPPVPAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWMYIIPVVLFLMMSGAPDAGSQGGGGGPGGWGAPGVPVRGEWLGLGLAAPHFPRGPDVPQRLPLAAGWSPSCPSSAELTPVPSPLPPLRPPGPALWGRAEFSASVPLFVVSSPRLALAWGAGTLGLLGSPELAQSRGGRALGTPSSTRGSSPVPAHSPAL", "length": 386, "header": "tr|A0A5G2RJE7-1|A0A5G2RJE7_PIG Isoform 1 of ER membrane protein complex subunit 10 OS=Sus scrofa OX=9823 GN=EMC10 PE=1 SV=2 CANONICAL=A0A5G2RJE7-1" }, "isoforms": [ { "isoform_ac": "A0A286ZQ46-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7/entry#A0A286ZQ46-1", "sequence": { "sequence": "MAGARAGATRLLLLLVMAAAAPSRARGSGCRSGASVRGAGAESREGEGCGTVGLLLEHSFEIDDSAHFRKRGSLLWNQQDGTLSLSQRQLNEEERGRLRDVAALNGVYRVRVPRRPGAPDGPESGGYVSSFVPACSLLESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLELFNTSVQLQPPVPAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWHLILGGAVLLTALRPAAPGPAPLPQEA", "length": 254, "header": "tr|A0A286ZQ46-1|A0A5G2RJE7_PIG Computationally mapped isoform of ER membrane protein complex subunit 10 OS=Sus scrofa OX=9823 GN=EMC10 PE=1 SV=2 CANONICAL=A0A5G2RJE7-1" }, "locus": { "chromosome": "6", "start_pos": 55321083, "end_pos": 55316505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066396.3", "url": "https://www.ensembl.org/id/ENSSSCT00000066396.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033592.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033592.2" } ] } }, { "isoform_ac": "A0A287B147-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7/entry#A0A287B147-1", "sequence": { "sequence": "MAGARAGATRLLLLLVMAAAAPSRARGSGCRSGASVRGVSAYSLCTEGEGCGDRDITESRPPTDDSAHFRKRGSLLWNQQDGTLSLSQRQLNEEERGRLRDVAALNGVYRVRVPRRPGAPDGPESGGYVSSFVPACSLLESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLELFNTSVQLQPPVPAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWHLILGGAVLLTALRPAAPGPAPLPQEA", "length": 255, "header": "tr|A0A287B147-1|A0A5G2RJE7_PIG Computationally mapped isoform of ER membrane protein complex subunit 10 OS=Sus scrofa OX=9823 GN=EMC10 PE=1 SV=3 CANONICAL=A0A5G2RJE7-1" }, "locus": { "chromosome": "6", "start_pos": 55321083, "end_pos": 55316505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052969.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052969.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049884.3", "url": "https://www.ensembl.org/id/ENSSSCP00000049884.3" } ] } }, { "isoform_ac": "A0A5G2QZS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7/entry#A0A5G2QZS0-1", "sequence": { "sequence": "MAGARAGATRLLLLLVMAAAAPSRARGSGCRSGASVRGAGAESREGEGCGTVGLLLEHSFEIDDSAHFRKRGSLLWNQQDGTLSLSQRQLNEEERGRLRDVAALNGVYRVRVPRRPGAPDGPESGGYVSSFVPACSLLESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLELFNTSVQLQPPVPAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYPGALRPAPLPRAFPGPLDVGPACPRLGPLCPSHWRLDRAGEGWGPAPCPASVGAGRWSPAPWSRHSWPGAGR", "length": 298, "header": "tr|A0A5G2QZS0-1|A0A5G2RJE7_PIG Computationally mapped isoform of ER membrane protein complex subunit 10 OS=Sus scrofa OX=9823 GN=EMC10 PE=1 SV=1 CANONICAL=A0A5G2RJE7-1" }, "locus": { "chromosome": "6", "start_pos": 55320452, "end_pos": 55316505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084753.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084753.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070393.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070393.2" } ] } }, { "isoform_ac": "A0A5G2RJE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7/entry#A0A5G2RJE7-1", "sequence": { "sequence": "MAGARAGATRLLLLLVMAAAAPSRARGSGCRSGASVRGAGAESREGEGCGTVGLLLEHSFEIDDSAHFRKRGSLLWNQQDGTLSLSQRQLNEEERGRLRDVAALNGVYRVRVPRRPGAPDGPESGGYVSSFVPACSLLESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLELFNTSVQLQPPVPAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWMYIIPVVLFLMMSGAPDAGSQGGGGGPGGWGAPGVPVRGEWLGLGLAAPHFPRGPDVPQRLPLAAGWSPSCPSSAELTPVPSPLPPLRPPGPALWGRAEFSASVPLFVVSSPRLALAWGAGTLGLLGSPELAQSRGGRALGTPSSTRGSSPVPAHSPAL", "length": 386, "header": "tr|A0A5G2RJE7-1|A0A5G2RJE7_PIG Isoform 1 of ER membrane protein complex subunit 10 OS=Sus scrofa OX=9823 GN=EMC10 PE=1 SV=2 CANONICAL=A0A5G2RJE7-1" }, "locus": { "chromosome": "6", "start_pos": 55321866, "end_pos": 55316505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073698.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073698.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071964.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071964.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZS0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZS0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7" } ], "pmid": "" }, { "name": "EMC complex", "id": "GO:0072546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072546", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell proliferation", "id": "GO:0001938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001938", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7" } ], "pmid": "" }, { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7" } ], "pmid": "" }, { "name": "protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "id": "GO:0045050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045050", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "membrane insertase activity", "id": "GO:0032977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032977", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RJE7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 386, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RJE7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RJE7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 182, "end_pos": 184 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RN75-1", "uniprot_ac": "A0A5G2RN75", "uniprot_id": "A0A5G2RN75_PIG", "mass": { "chemical_mass": 142432.0, "monoisotopic_mass": 142432.0 }, "refseq": {}, "gene_names": [ { "name": "RIPOR1", "type": "recommended", "evidence": [ { "id": "A0A5G2RN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ] } ], "protein_names": [ { "name": "Rho family-interacting cell polarization regulator 1", "type": "recommended", "evidence": [ { "id": "A0A5G2RN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75#function" }, { "database": "UniProtKB", "id": "ARBA00054594", "url": "https://www.uniprot.org/uniprotkb/ARBA00054594#function" }, { "database": "UniProtKB", "id": "A0A287AA53", "url": "https://www.uniprot.org/uniprotkb/A0A287AA53#function" }, { "database": "UniProtKB", "id": "A0A287AXV7", "url": "https://www.uniprot.org/uniprotkb/A0A287AXV7#function" }, { "database": "UniProtKB", "id": "A0A5G2QLT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLT9#function" }, { "database": "UniProtKB", "id": "F1S2J1", "url": "https://www.uniprot.org/uniprotkb/F1S2J1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RIPOR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75", "locus": { "chromosome": "6", "start_pos": 28183780, "end_pos": 28132115, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002774", "url": "https://www.ensembl.org/id/ENSSSCG00000002774" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002774", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002774", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AA53", "url": "https://www.uniprot.org/uniprotkb/A0A287AA53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AA53-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AA53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXT9", "url": "https://www.uniprot.org/uniprotkb/A0A287AXT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXV7", "url": "https://www.uniprot.org/uniprotkb/A0A287AXV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RN75-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2J1", "url": "https://www.uniprot.org/uniprotkb/F1S2J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2J1-1", "url": "https://www.uniprot.org/uniprotkb/F1S2J1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPSRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIKESKRNSRLGFLYDLDKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCVLESELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIEGSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLKRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFRRPETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEASGLDSLVWGPNLPVHPDPTHGEHPGPVPPALDPGHSATSPTLSTTDPVPSAHLDSVHKAINSSSPELPDPTHSTKSSTSSAISPTHSAPSLTHTTTGSTHKPIVSPLTTAGLTPSTTSPVQTTTSPTQKPVLSTLTPVAPTPSTTGPVQTTTSLSHTVTNLTHTVTSPINKPMVSSLTTSGPSPSTTGPALTTTSPTHTPATPAHKASMSTHPTRSPTPNAEGLVQTTMSTTRPVTSPTLITVSPSTFLDLATLSSPSANTDPTLPGTDPLSCSYPASTPCSQADPIASSTSHPSPTCSSWEPLTSPSPNPPEAICQSPGPPPTPLSPVPQQSDPSLARAAQVPLPGAARGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDENNDGPGDRPSSSPEPGAEESLDSPGARPLSTECAALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVFEAVCELSRRWDIPATSAQEVVQFSASRPGFLTFWDQCTEGLSPFICPVERVLLTFCNQYSARLSLRQPGLAEAVCFKFLEDALGQKLPRRPQPGPGEQLTIFQFWSYVEALDSSSMEAYVTETAEEVLLVRNLNSDDQAIVLKALRLAPEGRLQRDGLRALSSLLVHGNNRVMAAVSTQLRSLSLGPAFRERALLCFLDQLEDEDVQMRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEAGEWEIWVKLSSGTSWLLGVGVRCGQGWEDKDGARTTPDLILIHYRGRGSVCPSTVGGVTGCPAPHLWARQHGQHSILKFPPTGPQCPFPPTFRAYEALAGRVRAGSRHPSLTDSYQ", "length": 1322, "header": "tr|A0A5G2RN75-1|A0A5G2RN75_PIG Isoform 1 of Rho family-interacting cell polarization regulator 1 OS=Sus scrofa OX=9823 GN=RIPOR1 PE=1 SV=1 CANONICAL=A0A5G2RN75-1" }, "isoforms": [ { "isoform_ac": "A0A287AA53-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75/entry#A0A287AA53-1", "sequence": { "sequence": "MMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPSRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCVLESELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIEGSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLKRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFRRPETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEASGLDSLVWGPNLPVHPDPTHGEHPGPVPPALDPGHSATSPTLSTTDPVPSAHLDSVHKAINSSSPELPDPTHSTKSSTSSAISPTHSAPSLTHTTTGSTHKPIVSPLTTAGLTPSTTSPVQTTTSPTHTVTNLTHTVTSPTLTTTSPTHTPATPAHKASMSTHPTRSPTPNAEGLVQTTMSTTRPVTSPTLITVSPSTFLDLATLSSPSANTDPTLPGTDPLSCSYPASTPCSQADPIASSTSHPSPTCSSWEPLTSPSPNPPEAICQSPGPPPTPLSPVPQQSDPSLARAAQVPLPGAARGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDENNDGPGDRPSSSPEPGAEESLDSPGARPLSTECAALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVFEAVCELSRRWDIPATSAQEVVQFSASRPGFLTFWDQCTEGLSPFICPVERVLLTFCNQYSARLSLRQPGLAEAVCFKFLEDALGQKLPRRPQPGPGEQLTIFQFWSYVEALDSSSMEAYVTETAEEVLLVRNLNSDDQAIVLKALRLAPEGRLQRDGLRALSSLLVHGNNRVMAAVSTQLRSLSLGPAFRERALLCFLDQLEDEDVQMRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPRIFGPGSMASTAF", "length": 1204, "header": "tr|A0A287AA53-1|A0A5G2RN75_PIG Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Sus scrofa OX=9823 GN=RIPOR1 PE=1 SV=2 CANONICAL=A0A5G2RN75-1" }, "locus": { "chromosome": "6", "start_pos": 28180772, "end_pos": 28172599, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057409.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057409.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040886.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040886.2" } ] } }, { "isoform_ac": "A0A287AXT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75/entry#A0A287AXT9-1", "sequence": { "sequence": "MMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPSRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCVLESELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIEGSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLKRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFRRPETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEASGLDSLVWGPNLPVHPDPTHGEHPGPVPPALDPGHSATSPTLSTTDPVPSAHLDSVHKAINSSSPELPDPTHSTKSSTSSAISPTHSAPSLTHTTTGSTHKPIVSPLTTAGLTPSTTSPVQTTTSPTQKPVLSTLTPVAPTPSTTGPVQTTTSLSHTVTNLTHTVTSPINKPMVSSLTTSGPSPSTTGPALTTTSPTHTPATPAHKASMSTHPTRSPTPNAEGLVQTTMSTTRPVTSPTLITVSPSTFLDLATLSSPSANTDPTLPGTDPLSCSYPASTPCSQADPIASSTSHPSPTCSSWEPLTSPSPNPPEAICQSPGPPPTPLSPVPQQSDPSLARAAQVPLPGAARGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDENNDGPGDRPSSSPEPGAEESLDSPGARPLSTECAALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVFEAVCELSRRWDIPATSAQEVVQFSASRPGFLTFWDQCTEGLSPFICPVERVLLTFCNQYSARLSLRQPGLAEAGEWAASLPPLRSFLSSPVMGPQGKPGPPTQTC", "length": 1076, "header": "tr|A0A287AXT9-1|A0A5G2RN75_PIG Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Sus scrofa OX=9823 GN=RIPOR1 PE=1 SV=1 CANONICAL=A0A5G2RN75-1" }, "locus": { "chromosome": "6", "start_pos": 28179490, "end_pos": 28172599, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050539.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050539.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048948.1", "url": "https://www.ensembl.org/id/ENSSSCP00000048948.1" } ] } }, { "isoform_ac": "A0A287AXV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75/entry#A0A287AXV7-1", "sequence": { "sequence": "MSAKKRGSPARTHSMMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPSRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCVLESELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIEGSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLKRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFRRPETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEASGLDSLVWGPNLPVHPDPTHGEHPGPVPPALDPGHSATSPTLSTTDPVPSAHLDSVHKAINSSSPELPDPTHSTKSSTSSAISPTHSAPSLTHTTTGSTHKPIVSPLTTAGLTPSTTSPVQTTTSPTHTVTNLTHTVTSPTLTTTSPTHTPATPAHKASMSTHPTRSPTPNAEGLVQTTMSTTRPVTSPTLITVSPSTFLDLATLSSPSANTDPTLPGTDPLSCSYPASTPCSQADPIASSTSHPSPTCSSWEPLTSPSPNPPEAICQSPGPPPTPLSPVPQQSDPSLARAAQVPLPGAARGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDENNDGPGDRPSSSPEPGAEESLDSPGARPLSTECAALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVFEAVCELSRRWDIPATSAQEVVQFSASRPGFLTFWDQCTEGLSPFICPVERVLLTFCNQYSARLSLRQPGLAEAVCFKFLEDALGQKLPRRPQPGPGEQLTIFQFWSYVEALDSSSMEAYVTETAEEVLLVRNLNSDDQAIVLKALRLAPEGRLQRDGLRALSSLLVHGNNRVMAAVSTQLRSLSLGPAFRERALLCFLDQLEDEDVQMRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPRIFGPGSMASTAF", "length": 1218, "header": "tr|A0A287AXV7-1|A0A5G2RN75_PIG Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Sus scrofa OX=9823 GN=RIPOR1 PE=1 SV=2 CANONICAL=A0A5G2RN75-1" }, "locus": { "chromosome": "6", "start_pos": 28180772, "end_pos": 28171728, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057277.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057277.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048718.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048718.2" } ] } }, { "isoform_ac": "A0A5G2QLT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75/entry#A0A5G2QLT9-1", "sequence": { "sequence": "MMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPSRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCVLESELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIEGSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLKRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFRRPETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEASGLDSLVWGPNLPVHPDPTHGEHPGPVPPALDPGHSATSPTLSTTDPVPSAHLDSVHKAINSSSPELPDPTHSTKSSTSSAISPTHSAPSLTHTTTGSTHKPIVSPLTTAGLTPSTTSPVQTTTSPTQKPVLSTLTPVAPTPSTTGPVQTTTSLSHTVTNLTHTVTSPINKPMVSSLTTSGPSPSTTGPALTTTSPTHTPATPAHKASMSTHPTRSPTPNAEGLVQTTMSTTRPVTSPTLITVSPSTFLDLATLSSPSANTDPTLPGTDPLSCSYPASTPCSQADPIASSTSHPSPTCSSWEPLTSPSPNPPEAICQSPGPPPTPLSPVPQQSDPSLARAAQVPLPGAARGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDENNDGPGDRPSSSPEPGAEESLDSPGARPLSTECAALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVFEAVCELSRRWDIPATSAQEGKGCVDSGLCLPQSSSPALRHLHTCHPPPPPTPAFVADSFVHLLTVVQFSASRPGFLTFWDQCTEGLSPFICPVERVLLTFCNQYSARLSLRQPGLAEAVCFKFLEDALGQKLPRRPQPGPGEQLTIFQFWSYVEALDSSSMEAYVTETAEEVLLVRNLNSDDQAIVLKALRLAPEGRLQRDGLRALSSLLVHGNNRVMAAVSTQLRSLSLGPAFRERALLCFLDQLEDEDVQMRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPRIFGPGSMASTAF", "length": 1298, "header": "tr|A0A5G2QLT9-1|A0A5G2RN75_PIG Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Sus scrofa OX=9823 GN=RIPOR1 PE=1 SV=1 CANONICAL=A0A5G2RN75-1" }, "locus": { "chromosome": "6", "start_pos": 28180772, "end_pos": 28172599, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080694.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080694.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065822.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065822.1" } ] } }, { "isoform_ac": "A0A5G2RN75-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75/entry#A0A5G2RN75-1", "sequence": { "sequence": "MMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPSRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIKESKRNSRLGFLYDLDKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCVLESELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIEGSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLKRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFRRPETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEASGLDSLVWGPNLPVHPDPTHGEHPGPVPPALDPGHSATSPTLSTTDPVPSAHLDSVHKAINSSSPELPDPTHSTKSSTSSAISPTHSAPSLTHTTTGSTHKPIVSPLTTAGLTPSTTSPVQTTTSPTQKPVLSTLTPVAPTPSTTGPVQTTTSLSHTVTNLTHTVTSPINKPMVSSLTTSGPSPSTTGPALTTTSPTHTPATPAHKASMSTHPTRSPTPNAEGLVQTTMSTTRPVTSPTLITVSPSTFLDLATLSSPSANTDPTLPGTDPLSCSYPASTPCSQADPIASSTSHPSPTCSSWEPLTSPSPNPPEAICQSPGPPPTPLSPVPQQSDPSLARAAQVPLPGAARGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDENNDGPGDRPSSSPEPGAEESLDSPGARPLSTECAALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVFEAVCELSRRWDIPATSAQEVVQFSASRPGFLTFWDQCTEGLSPFICPVERVLLTFCNQYSARLSLRQPGLAEAVCFKFLEDALGQKLPRRPQPGPGEQLTIFQFWSYVEALDSSSMEAYVTETAEEVLLVRNLNSDDQAIVLKALRLAPEGRLQRDGLRALSSLLVHGNNRVMAAVSTQLRSLSLGPAFRERALLCFLDQLEDEDVQMRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEAGEWEIWVKLSSGTSWLLGVGVRCGQGWEDKDGARTTPDLILIHYRGRGSVCPSTVGGVTGCPAPHLWARQHGQHSILKFPPTGPQCPFPPTFRAYEALAGRVRAGSRHPSLTDSYQ", "length": 1322, "header": "tr|A0A5G2RN75-1|A0A5G2RN75_PIG Isoform 1 of Rho family-interacting cell polarization regulator 1 OS=Sus scrofa OX=9823 GN=RIPOR1 PE=1 SV=1 CANONICAL=A0A5G2RN75-1" }, "locus": { "chromosome": "6", "start_pos": 28180891, "end_pos": 28172599, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076936.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076936.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074225.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074225.1" } ] } }, { "isoform_ac": "F1S2J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75/entry#F1S2J1-1", "sequence": { "sequence": "MMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPSRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIKESKRNSRLGFLYDLDKSMCVLESELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIEGSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLKRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFRRPETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEASGLDSLVWGPNLPVHPDPTHGEHPGPVPPALDPGHSATSPTLSTTDPVPSAHLDSVHKAINSSSPELPDPTHSTKSSTSSAISPTHSAPSLTHTTTGSTHKPIVSPLTTAGLTPSTTSPVQTTTSPTQKPVLSTLTPVAPTPSTTGPVQTTTSLSHTVTNLTHTVTSPINKPMVSSLTTSGPSPSTTGPALTTTSPTHTPATPAHKASMSTHPTRSPTPNAEGLVQTTMSTTRPVTSPTLITVSPSTFLDLATLSSPSANTDPTLPGTDPLSCSYPASTPCSQADPIASSTSHPSPTCSSWEPLTSPSPNPPEAICQSPGPPPTPLSPVPQQSDPSLARAAQVPLPGAARGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDENNDGPGDRPSSSPEPGAEESLDSPGARPLSTECAALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVFEAVCELSRRWDIPATSAQEVVQFSASRPGFLTFWDQCTEGLSPFICPVERVLLTFCNQYSARLSLRQPGLAEAVCFKFLEDALGQKLPRRPQPGPGEQLTIFQFWSYVEALDSSSMEAYVTETAEEVLLVRNLNSDDQAIVLKALRLAPEGRLQRDGLRALSSLLVHGNNRVMAAVSTQLRSLSLGPAFRERALLCFLDQLEDEDVQMRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEAGEWEIWVKLSSGTSWLLGVGVRCGQGWEDKDGARTTPDLILIHYRGRGSVCPSTVGGVTGCPAPHLWARQHGQHSILKFPPTGPQCPFPPTFRAYEALAGRVRAGSRHPSLTDSYQ", "length": 1271, "header": "tr|F1S2J1-1|A0A5G2RN75_PIG Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Sus scrofa OX=9823 GN=RIPOR1 PE=1 SV=3 CANONICAL=A0A5G2RN75-1" }, "locus": { "chromosome": "6", "start_pos": 28180891, "end_pos": 28172599, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003072.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003072.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002993.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002993.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 590, "start_aa": "Thr", "end_pos": 590, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr590", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 746, "start_aa": "Thr", "end_pos": 746, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr746", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 773, "start_aa": "Thr", "end_pos": 773, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr773", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QLT9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLT9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "pmid": "" }, { "name": "positive regulation of intracellular protein transport", "id": "GO:0090316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090316", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "pmid": "" }, { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "pmid": "" }, { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "pmid": "" }, { "name": "establishment of Golgi localization", "id": "GO:0051683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051683", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "pmid": "" }, { "name": "protein localization to Golgi apparatus", "id": "GO:0034067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034067", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "14-3-3 protein binding", "id": "GO:0071889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071889", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN75", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN75" }, { "id": "PF15903", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15903" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM65 N-terminal", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 346, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 590, 746, 773 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 353, "end_pos": 355 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 609, "end_pos": 611 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RIF5-1", "uniprot_ac": "A0A5G2RIF5", "uniprot_id": "A0A5G2RIF5_PIG", "mass": { "chemical_mass": 61496.0, "monoisotopic_mass": 61496.0 }, "refseq": {}, "gene_names": [ { "name": "TBCE", "type": "recommended", "evidence": [ { "id": "A0A5G2RIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5" } ] } ], "protein_names": [ { "name": "Tubulin-specific chaperone E", "type": "recommended", "evidence": [ { "id": "A0A5G2RIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5/entry#names_and_taxonomy" } ] }, { "name": "Tubulin-folding cofactor E", "type": "synonym", "evidence": [ { "id": "A0A5G2RIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Tubulin-folding protein; involved in the second step of the tubulin folding pathway and in the regulation of tubulin heterodimer dissociation. Required for correct organization of microtubule cytoskeleton and mitotic splindle, and maintenance of the neuronal microtubule network.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R673", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R673#function" }, { "database": "UniProtKB", "id": "ARBA00045331", "url": "https://www.uniprot.org/uniprotkb/ARBA00045331#function" }, { "database": "UniProtKB", "id": "A0A5G2RIF5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIF5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TBCE", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5", "locus": { "chromosome": "14", "start_pos": 55816668, "end_pos": 55901171, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034844", "url": "https://www.ensembl.org/id/ENSSSCG00000034844" } ] } } ], "crossref": [ { "id": "A0A5G2RIF5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034844", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034844", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NENSTFA", "url": "https://omabrowser.org/oma/group/NENSTFA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR18849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18849:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18849:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AE62", "url": "https://www.uniprot.org/uniprotkb/A0A287AE62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AE62-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AE62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QE05", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QE05-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKM3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QS31-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QS31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R673", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R673", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R673-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R673-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8G0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RIF5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RIF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJI2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNDTLTSDVTGRRVEVNGEHATVRFSGIVPPVAGLWLGVEWDNPERGKHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGVDFLTAIKNRYVLEDEPEEEEKEQTVIIGNKPVETIGFDSVVKQQSQLSKLQEVSLRNCAVNGAGDKRGIAQACPNIRSIDLSKNLLSSWDDVIAIADQLKHLEVLNLSENKLRFPSGLPSPTGTFSMLKVLVLNRTGVTWAEVLRCASGWPVLEKLYLESNNIIISERPADVLQTVKLLDLSSNQLIDENQLFLIAYLPRLEQLILSDIGISSLHFPDAGIGCKTAMFPSLQYLVLNDNQISQWSFINELDKLQSLHALSCARNPLTEEGSKDAQTTRQFIIAKIGQLRTLNKCVIQPEERRGAELDYRKAFGNEWKKAGGHQDPDKDRPNEEFLAAHPRYQSLCLSSYTCARPGLQGFPLGQFPLEYGAPEDGELKTPQPFLLRNELLTLIKYPNQLGQRVIEKQLPESMTVQKVKGFLSRLLKVSVSELLLSYESPKMPGREIELENDQQSLQFYSIENGDCLLVRW", "length": 548, "header": "tr|A0A5G2RIF5-1|A0A5G2RIF5_PIG Isoform 1 of Tubulin-specific chaperone E OS=Sus scrofa OX=9823 GN=TBCE PE=1 SV=2 CANONICAL=A0A5G2RIF5-1" }, "isoforms": [ { "isoform_ac": "A0A287AE62-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5/entry#A0A287AE62-1", "sequence": { "sequence": "MNDTLTSDVTGRRVEVNGEHATVRFSGIVPPVAGLWLGVEWDNPERGKHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGVDFLTAIKNRYVLEDEPEEEEKEQTVIIGNKPVETIGFDSVVKQQSQLSKLQEVSLRNCAVNGAGDKRGIAQACPNIRSIDLSKNLLSSWDDVIAIADQLKHLEVLNLSENKLRFPSGLPSPTGTFSMLKVLVLNRTGVTWAEVLRCASGWPVLEKLYLESNNIIISERPADVLQTVKLLDLSSNQLIDENQLFLIAYLPRLEQLILSDIGISSLHFPDAGIGCKTAMFPSLQYLVLNDNQISQWSFINELDKLQSLHALSCARNPLTEEGSKDAQTTRQFIIAKIGQLRTLNKCVIQPEERRGAELDYRKAFGNEWKKAGGHQDPDKDRPNEEFLAAHPRYQSLCLKYGAPEDGELKTPQPFLLRNELLSKNLTFQLIWI", "length": 459, "header": "tr|A0A287AE62-1|A0A5G2RIF5_PIG Computationally mapped isoform of Tubulin-specific chaperone E OS=Sus scrofa OX=9823 GN=TBCE PE=1 SV=1 CANONICAL=A0A5G2RIF5-1" }, "locus": { "chromosome": "14", "start_pos": 55880961, "end_pos": 55820943, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057828.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057828.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042305.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042305.1" } ] } }, { "isoform_ac": "A0A5G2QE05-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5/entry#A0A5G2QE05-1", "sequence": { "sequence": "MNDTLTSDVTGRRVEVNGEHATVRFSGIVPPVAGLWLGVEWDNPERGKHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGVDFLTAIKNRYVLEDEPEEEEKEQTVIIGNKPVETIGFDSVVKQQSQLSKLQEVSLRNCAVNGAGDKRGIAQACPNIRSIDLSKNLLSSWDDVIAIADQLKHLEVLNLSENKLRFPSGLPSPTGTFSMLKVLVLNRTGVTWAEVLRCASGWPVLEKLYLESNNIIISERPADVLQTVKLLDLSSNQLIDENQLFLIAYLPRLEQLILSDIGISSLHFPDAGIGCKTAMFPSLQYLVLNDNQISQWSFINELDKLQSLHALSCARNPLTEEGSKDAQTTRQFIIAKIGQLRTLNKCVIQPEERRGAELDYRKAFGNEWKKAGGHQDPDKDRPNEEFLAAHPRYQSLCLKYGAPEDGELKTPQPFLLRNELLTEIKYPNQLGQRVIEKQLPEEELRLERVSHILTVPEPLTSVLSVFHRIHDSSKGERLPVASPQSVCVRTSLVL", "length": 521, "header": "tr|A0A5G2QE05-1|A0A5G2RIF5_PIG Computationally mapped isoform of Tubulin-specific chaperone E OS=Sus scrofa OX=9823 GN=TBCE PE=1 SV=2 CANONICAL=A0A5G2RIF5-1" }, "locus": { "chromosome": "14", "start_pos": 55880961, "end_pos": 55817131, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072736.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072736.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062388.2", "url": "https://www.ensembl.org/id/ENSSSCP00000062388.2" } ] } }, { "isoform_ac": "A0A5G2QKM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5/entry#A0A5G2QKM3-1", "sequence": { "sequence": "MNDTLTSDVTGRRVEVNGEHATVRFSGIVPPVAGLWLGVEWDNPERGKHDGSHEGTVYFKCSQLSKLQEVSLRNCAVNGAGDKRGIAQACPNIRSIDLSKNLLSSWDDVIAIADQLKHLEVLNLSENKLRFPSGLPSPTGTFSMLKVLVLNRTGVTWAEVLRCASGWPVLEKLYLESNNIIISERPADVLQTVKLLDLSSNQLIDENQLFLIAYLPRLEQLILSDIGISSLHFPDAGIGCKTAMFPSLQYLVLNDNQISQWSFINELDKLQSLHALSCARNPLTEEGSKDAQTTRQFIIAKIGQLRTLNKCVIQPEERRGAELDYRKAFGNEWKKAGGHQDPDKDRPNEEFLAAHPRYQSLCLSSYTCARPGLQGFPLGQFPLEYGAPEDGELKTPQPFLLRNELLTLIKYPNQLGQRVIEKQLPESMTVQKVKGFLSRLLKVSVSELLLSYESPKMPGREIELENDQQSLQFYSIENGDCLLVRW", "length": 486, "header": "tr|A0A5G2QKM3-1|A0A5G2QKM3_PIG Computationally mapped isoform of Tubulin-specific chaperone E OS=Sus scrofa OX=9823 GN=TBCE PE=3 SV=1 CANONICAL=A0A5G2RIF5-1" }, "locus": { "chromosome": "14", "start_pos": 55880961, "end_pos": 55816859, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072878.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072878.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064539.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064539.1" } ] } }, { "isoform_ac": "A0A5G2QS31-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5/entry#A0A5G2QS31-1", "sequence": { "sequence": "MNDTLTSDVTGRRVEVNGEHATVRFSGIVPPVAELHPWHMDVPRLGVELKLQLSACITAHVPGLWLGVEWDNPERGKHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGVDFLTAIKNRYVLEDEPEEEEKEQTVIIGNKPVETIGFDSVVKQQSQLSKLQEVSLRNCAVNGAGDKRGIAQACPNIRSIDLSKNLLSSWDDVIAIADQLKHLEVLNLSENKLRFPSGLPSPTGTFSMLKVLVLNRTGVTWAEVLRCASGWPVLEKLYLESNNIIISERPADVLQTVKLLDLSSNQLIDENQLFLIAYLPRLEQLILSDIGISSLHFPDAGIGCKTAMFPSLQYLVLNDNQISQWSFINELDKLQSLHALSCARNPLTEEGSKDAQTTRQFIIAKIGQLRTLNKCVIQPEERRGAELDYRKAFGNEWKKAGGHQDPDKDRPNEEFLAAHPRYQSLCLKYGAPEDGELKTPQPFLLRNELLTLR", "length": 480, "header": "tr|A0A5G2QS31-1|A0A5G2RIF5_PIG Computationally mapped isoform of Tubulin-specific chaperone E OS=Sus scrofa OX=9823 GN=TBCE PE=1 SV=2 CANONICAL=A0A5G2RIF5-1" }, "locus": { "chromosome": "14", "start_pos": 55880961, "end_pos": 55820457, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076980.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076980.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067735.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067735.2" } ] } }, { "isoform_ac": "A0A5G2R673-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5/entry#A0A5G2R673-1", "sequence": { "sequence": "MNDTLTSDVTGRRVEVNGEHATVRFSGIVPPVAGLWLGVEWDNPERGKHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGVDFLTAIKNRYVLEDEPEEEEKEQTVIIGNKPVETIGFDSVVKQQSENKLRFPSGLPSPTGTFSMLKVLVLNRTGVTWAEVLRCASGWPVLEKLYLESNNIIISERPADVLQTVKLLDLSSNQLIDENQLFLIAYLPRLEQLILSDIGISSLHFPDAGIGCKTAMFPSLQYLVLNDNQISQWSFINELDKLQSLHALSCARNPLTEEGSKDAQTTRQFIIAKIGQLRTLNKCVIQPEERRGAELDYRKAFGNEWKKAGGHQDPDKDRPNEEFLAAHPRYQSLCLKYGAPEDGELKTPQPFLLRNELLTLIKYPNQLGQRVIEKQLPESMTVQKVKGFLSRLLKVSVSELLLSYESPKMPGREIELENDQQSLQFYSIENGDCLLVRW", "length": 465, "header": "tr|A0A5G2R673-1|A0A5G2RIF5_PIG Computationally mapped isoform of Tubulin-specific chaperone E OS=Sus scrofa OX=9823 GN=TBCE PE=1 SV=1 CANONICAL=A0A5G2RIF5-1" }, "locus": { "chromosome": "14", "start_pos": 55880961, "end_pos": 55816859, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078997.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078997.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069621.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069621.1" } ] } }, { "isoform_ac": "A0A5G2R8G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5/entry#A0A5G2R8G0-1", "sequence": { "sequence": "MNDTLTSDVTGRRVEVNGEHATVRFSGIVPPVAGLWLGVEWDNPERGKHDGSHEGTVYFKCRLQYSPVCSNYYSKHPTGGSFIRPNKVNFGVDFLTAIKNRYVLEDEPEEEEKEQTVIIGNKPVETIGFDSVVKQQSQLSKLQEVSLRNCAVNGAGDKRGIAQACPNIRSIDLSKNLLSSWDDVIAIADQLKHLEVLNLSENKLRFPSGLPSPTGTFSMLKVLVLNRTGVTWAEVLRCASGWPVLEKLYLESNNIIISERPADVLQTVKLLDLSSNQLIDENQLFLIAYLPRLEQLILSDIGISSLHFPDAGIGCKTAMFPSLQYLVLNDNQISQWSFINELDKLQSLHALSCARNPLTEEGSKDAQTTRQFIIAKIGQLRTLNKCVIQPEERRGAELDYRKAFGNEWKKAGGHQDPDKDRPNEEFLAAHPRYQSLCLKYGAPEDGELKTPQPFLLRNELLTLR", "length": 464, "header": "tr|A0A5G2R8G0-1|A0A5G2RIF5_PIG Computationally mapped isoform of Tubulin-specific chaperone E OS=Sus scrofa OX=9823 GN=TBCE PE=1 SV=2 CANONICAL=A0A5G2RIF5-1" }, "locus": { "chromosome": "14", "start_pos": 55880961, "end_pos": 55820457, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073096.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073096.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070407.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070407.2" } ] } }, { "isoform_ac": "A0A5G2RIF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5/entry#A0A5G2RIF5-1", "sequence": { "sequence": "MNDTLTSDVTGRRVEVNGEHATVRFSGIVPPVAGLWLGVEWDNPERGKHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGVDFLTAIKNRYVLEDEPEEEEKEQTVIIGNKPVETIGFDSVVKQQSQLSKLQEVSLRNCAVNGAGDKRGIAQACPNIRSIDLSKNLLSSWDDVIAIADQLKHLEVLNLSENKLRFPSGLPSPTGTFSMLKVLVLNRTGVTWAEVLRCASGWPVLEKLYLESNNIIISERPADVLQTVKLLDLSSNQLIDENQLFLIAYLPRLEQLILSDIGISSLHFPDAGIGCKTAMFPSLQYLVLNDNQISQWSFINELDKLQSLHALSCARNPLTEEGSKDAQTTRQFIIAKIGQLRTLNKCVIQPEERRGAELDYRKAFGNEWKKAGGHQDPDKDRPNEEFLAAHPRYQSLCLSSYTCARPGLQGFPLGQFPLEYGAPEDGELKTPQPFLLRNELLTLIKYPNQLGQRVIEKQLPESMTVQKVKGFLSRLLKVSVSELLLSYESPKMPGREIELENDQQSLQFYSIENGDCLLVRW", "length": 548, "header": "tr|A0A5G2RIF5-1|A0A5G2RIF5_PIG Isoform 1 of Tubulin-specific chaperone E OS=Sus scrofa OX=9823 GN=TBCE PE=1 SV=2 CANONICAL=A0A5G2RIF5-1" }, "locus": { "chromosome": "14", "start_pos": 55880961, "end_pos": 55816859, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080822.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080822.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071362.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071362.2" } ] } }, { "isoform_ac": "A0A8W4FJI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5/entry#A0A8W4FJI2-1", "sequence": { "sequence": "MNDTLTSDVTGRRVEVNGEHATVRFSGIVPPVAGGSFIRPNKVNFGVDFLTAIKNRYVLEDEPEEEEKEQTVIIGNKPVETIGFDSVVKQQSQLSKLQEVSLRNCAVNGAGDKRGIAQACPNIRSIDLSKNLLSSWDDVIAIADQLKHLEVLNLSENKLRFPSGLPSPTGTFSMLKVLVLNRTGVTWAEVLRCASGWPVLEKLYLESNNIIISERPADVLQTVKLLDLSSNQLIDENQLFLIAYLPRLEQLILSDIGISSLHFPDAGIGCKTAMFPSLQYLVLNDNQISQWSFINELDKLQSLHALSCARNPLTEEGSKDAQTTRQFIIAKIGQLRTLNKCVIQPEERRGAELDYRKAFGNEWKKAGGHQDPDKDRPNEEFLAAHPRYQSLCLKYGAPEDGELKTPQPFLLRNELLSKNLTFQLIWI", "length": 427, "header": "tr|A0A8W4FJI2-1|A0A5G2RIF5_PIG Computationally mapped isoform of Tubulin-specific chaperone E OS=Sus scrofa OX=9823 GN=TBCE PE=1 SV=1 CANONICAL=A0A5G2RIF5-1" }, "locus": { "chromosome": "14", "start_pos": 55880961, "end_pos": 55820943, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095083.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095083.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079376.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079376.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QE05", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE05" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q15813-1", "protein_name": "Tubulin-specific chaperone E", "gene_name": "TBCE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDTLTADVIGRRVEVNGEHATVRFAGVVPPVAGPWLGVEWDNPERGKHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIGNKPVETIGFDSIMKQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQLRHLEVLNVSENKLKFPSGSVLTGTLSVLKVLVLNQTGITWAEVLRCVAGCPGLEELYLESNNIFISERPTDVLQTVKLLDLSSNQLIDENQLYLIAHLPRLEQLILSDTGISSLHFPDAGIGCKTSMFPSLKYLVVNDNQISQWSFFNELEKLPSLRALSCLRNPLTKEDKEAETARLLIIASIGQLKTLNKCEILPEERRRAELDYRKAFGNEWKQAGGHKDPEKNRLSEEFLTAHPRYQFLCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGSMTIQKVKGLLSRLLKVPVSDLLLSYESPKKPGREIELENDLKSLQFYSVENGDCLLVRW", "length": 527 }, "evidence": [ { "id": "A0A5G2RIF5", "url": "https://omabrowser.org/oma/group/A0A5G2RIF5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIF5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIF5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIF5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5" } ], "pmid": "" }, { "name": "tubulin complex assembly", "id": "GO:0007021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007021", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIF5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIF5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5" } ], "pmid": "" }, { "name": "post-chaperonin tubulin folding pathway", "id": "GO:0007023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007023", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIF5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIF5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RIF5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 548, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RIF5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIF5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIF5" }, { "id": "PS50245", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50245" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CAP-Gly", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 71, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 2, "end_pos": 4 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RKR1-1", "uniprot_ac": "A0A5G2RKR1", "uniprot_id": "A0A5G2RKR1_PIG", "mass": { "chemical_mass": 168286.0, "monoisotopic_mass": 168286.0 }, "refseq": { "ac": "XP_001925389", "name": "nischarin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925389" }, "gene_names": [ { "name": "NISCH", "type": "recommended", "evidence": [ { "id": "A0A5G2RKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1" } ] }, { "name": "NISCH", "type": "synonym", "evidence": [ { "id": "XP_001925389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925389" } ] } ], "protein_names": [ { "name": "Nischarin", "type": "recommended", "evidence": [ { "id": "A0A5G2RKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1/entry#names_and_taxonomy" } ] }, { "name": "Imidazoline receptor 1", "type": "synonym", "evidence": [ { "id": "A0A5G2RKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1/entry#names_and_taxonomy" } ] }, { "name": "Imidazoline-1 receptor", "type": "synonym", "evidence": [ { "id": "A0A5G2RKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1/entry#names_and_taxonomy" } ] }, { "name": "nischarin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_001925389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925389" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NISCH", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1", "locus": { "chromosome": "13", "start_pos": 34630303, "end_pos": 34595782, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011442", "url": "https://www.ensembl.org/id/ENSSSCG00000011442" } ] } } ], "crossref": [ { "id": "A0A5G2RKR1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RKR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011442", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011442", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06875", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06875", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156417", "url": "https://www.ncbi.nlm.nih.gov/gene/100156417", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156417", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156417", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WSKNDLC", "url": "https://omabrowser.org/oma/group/WSKNDLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RKR1", "url": "https://www.orthodb.org/?gene=A0A5G2RKR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1SIW1", "url": "https://www.orthodb.org/?gene=F1SIW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23142", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23142", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001925389", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925389", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AIR8", "url": "https://www.uniprot.org/uniprotkb/A0A287AIR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AIR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AIR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SIW1", "url": "https://www.uniprot.org/uniprotkb/F1SIW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SIW1-1", "url": "https://www.uniprot.org/uniprotkb/F1SIW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAARSFGPEPEAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKLVAEKKIDKSLLPPKKIIGKNSRSLVEKREKDLEVYLQTLLATFPDVAPRVLAHFLHFHFYEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQHLPFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATMSVCFSATSMKEVLVPEASEFDEWEPAGAALEGPVTAIIPTWQALTALDLSHNSISEIDESVKLIPKIEFLDLSHNGVLVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNIKTLNLAGNLLGSLHGLHKLYSLVNLDLSNNRIEQMEEVRSIGSLPCLEHVALLNNPLSIIPDYRTKVLAQFGERASEVCLDNTVTTEKELDTVEVLKAIQKAKEVKSKLSNTEKKVSEDSRLSAATCIRPSGSPPTVAPTSASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEDRPIARGCSDSLESIPAGQALCDEIRDVPGAVGGASPEHSEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEGRGEQGEEEEEEEEEDVAENRYFEMGPPDVEEEEEGGPGEEEEEEEEEEEEEGEEGEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLFIISDATNLHEFHADLRSCFAPQHMAMLCSPVLYGSHTSLQEFLRQLLTFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRIYNQLRASLQDLKTVVIAKTPATGGRPQSPLADGQPTEGRASDDQHLQEALEEVPVPALAPAEAPGLAKIPAPAEASEPALVLPEAPTEASASEETPAEASAGASVPAPAEGTAQAEAPAQYPSERLIQSMSEENQIPSHLPACPSLQHIASLQGSAVVEFFHNSIAEVENEELRHLLWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQTVNVGLFDQYFRLTGSSPAQVVTCLTRDSYLTHCFLQHVMAVLSLLERTPSPEPVDKDFYSEFGNKTTGKVENYELIHSSRVKFTYPSEEEIGDLTFTVAQKMADPEKAPGLSILLYVQAFQVGMPLPGRCRGLLRPKTLLLTSAEIFLLDEDFVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHDLMGSVTLDHFGEEPGGPARAGQGREVQWQVFIPSAESREKLISLLARQWEALCGRELPVELTG", "length": 1520, "header": "tr|A0A5G2RKR1-1|A0A5G2RKR1_PIG Isoform 1 of Nischarin OS=Sus scrofa OX=9823 GN=NISCH PE=1 SV=2 CANONICAL=A0A5G2RKR1-1" }, "isoforms": [ { "isoform_ac": "A0A287AIR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1/entry#A0A287AIR8-1", "sequence": { "sequence": "MAAAARSFGPEPEAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKLVAEKKIDKSLLPPKKIIGKNSRSLVEKREKDLEVYLQTLLATFPDVAPRVLAHFLHFHFYEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQHLPFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATMSVCFSATSMKEVLVPEASEFDEWEPAGAALEGPVTAIIPTWQALTALDLSHNSISEIDESVKLIPKIEFLDLSHNGVLVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNIKTLNLAGNLLGSLHGLHKLYSLVNLDLSNNRIEQMEEVRSIGSLPCLEHVALLNNPLSIIPDYRTKVLAQFGERASEVCLDNTVTTEKELDTVEVLKAIQKAKEVKSKLSNTEKKVSEDSRLSAATCIRPSGSPPTVAPTSASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEDRPIARGCSDSLESIPAGQALCDEIRDVPGAVGGASPEHSEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEGRGEQGEEEEEEEEEDVAENRYFEMGPPDVEEEEEDATNLHEFHADLRSCFAPQHMAMLCSPVLYGSHTSLQEFLRQLLTFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRIYNQLRASLQDLKTVVIAKTPATGGRPQSPLADGQPTEGRASDDQHLQEALEEVPVPALAPAEAPGLAKIPAPAEASEPALVLPEAPTEASASEETPAEASAGASVPAPAEGTAQAEAPAQYPSERLIQSMSEENQIPSHLPACPSLQHIASLQGSAVVEFFHNSIAEVENEELRHLLWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQTVNVGLFDQYFRLTGSSPAQVVTCLTRDSYLTHCFLQHVMAVLSLLERTPSPEPVDKDFYSEFGNKTTGKVENYELIHSSRVKFTYPSEEEIGDLTFTVAQKMADPEKAPGLSILLYVQAFQVGMPLPGRCRGLLRPKTLLLTSAEIFLLDEDFVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHDLMGSVTLDHFGEEPGGPARAGQGREVQWQVFIPSAESREKLISLLARQWEALCGRELPVELTG", "length": 1387, "header": "tr|A0A287AIR8-1|A0A5G2RKR1_PIG Computationally mapped isoform of Nischarin OS=Sus scrofa OX=9823 GN=NISCH PE=1 SV=1 CANONICAL=A0A5G2RKR1-1" }, "locus": { "chromosome": "13", "start_pos": 34629709, "end_pos": 34595929, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057099.1", "url": "https://www.ensembl.org/id/ENSSSCT00000057099.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043789.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043789.1" } ] } }, { "isoform_ac": "A0A5G2RKR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1/entry#A0A5G2RKR1-1", "sequence": { "sequence": "MAAAARSFGPEPEAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKLVAEKKIDKSLLPPKKIIGKNSRSLVEKREKDLEVYLQTLLATFPDVAPRVLAHFLHFHFYEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQHLPFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATMSVCFSATSMKEVLVPEASEFDEWEPAGAALEGPVTAIIPTWQALTALDLSHNSISEIDESVKLIPKIEFLDLSHNGVLVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNIKTLNLAGNLLGSLHGLHKLYSLVNLDLSNNRIEQMEEVRSIGSLPCLEHVALLNNPLSIIPDYRTKVLAQFGERASEVCLDNTVTTEKELDTVEVLKAIQKAKEVKSKLSNTEKKVSEDSRLSAATCIRPSGSPPTVAPTSASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEDRPIARGCSDSLESIPAGQALCDEIRDVPGAVGGASPEHSEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEGRGEQGEEEEEEEEEDVAENRYFEMGPPDVEEEEEGGPGEEEEEEEEEEEEEGEEGEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLFIISDATNLHEFHADLRSCFAPQHMAMLCSPVLYGSHTSLQEFLRQLLTFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRIYNQLRASLQDLKTVVIAKTPATGGRPQSPLADGQPTEGRASDDQHLQEALEEVPVPALAPAEAPGLAKIPAPAEASEPALVLPEAPTEASASEETPAEASAGASVPAPAEGTAQAEAPAQYPSERLIQSMSEENQIPSHLPACPSLQHIASLQGSAVVEFFHNSIAEVENEELRHLLWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQTVNVGLFDQYFRLTGSSPAQVVTCLTRDSYLTHCFLQHVMAVLSLLERTPSPEPVDKDFYSEFGNKTTGKVENYELIHSSRVKFTYPSEEEIGDLTFTVAQKMADPEKAPGLSILLYVQAFQVGMPLPGRCRGLLRPKTLLLTSAEIFLLDEDFVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHDLMGSVTLDHFGEEPGGPARAGQGREVQWQVFIPSAESREKLISLLARQWEALCGRELPVELTG", "length": 1520, "header": "tr|A0A5G2RKR1-1|A0A5G2RKR1_PIG Isoform 1 of Nischarin OS=Sus scrofa OX=9823 GN=NISCH PE=1 SV=2 CANONICAL=A0A5G2RKR1-1" }, "locus": { "chromosome": "13", "start_pos": 34629709, "end_pos": 34595929, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070171.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070171.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072757.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072757.2" } ] } }, { "isoform_ac": "F1SIW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1/entry#F1SIW1-1", "sequence": { "sequence": "MAAAARSFGPEPEAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKLVAEKKIDKSLLPPKKIIGKNSRSLVEKREKDLEVYLQTLLATFPDVAPRVLAHFLHFHFYEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQHLPFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATMSVCFSATSMKEVLVPEASEFDEWEPAGAALEGPVTAIIPTWQALTALDLSHNSISEIDESVKLIPKIEFLDLSHNGVLVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNIKTLNLAGNLLGSLHGLHKLYSLVNLDLSNNRIEQMEEVRSIGSLPCLEHVALLNNPLSIIPDYRTKVLAQFGERASEVCLDNTVTTEKELDTVEVLKAIQKAKEVKSKLSNTEKKVSEDSRLSAATCIRPSGSPPTVAPTSASLPQPILSNQGILGDE", "length": 516, "header": "tr|F1SIW1-1|F1SIW1_PIG Computationally mapped isoform of Nischarin OS=Sus scrofa OX=9823 GN=NISCH PE=1 SV=4 CANONICAL=A0A5G2RKR1-1" }, "locus": { "chromosome": "13", "start_pos": 34616522, "end_pos": 34595929, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012522.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012522.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012194.4", "url": "https://www.ensembl.org/id/ENSSSCP00000012194.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1088, "start_aa": "Thr", "end_pos": 1088, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1088", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 498, "start_aa": "Thr", "end_pos": 498, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr498", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AIR8", "url": "https://www.uniprot.org/uniprotkb/A0A287AIR8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156417", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156417", "resource": "KEGG Pathway" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-SSC-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" }, { "id": "R-SSC-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A6X1-1", "protein_name": "Nischarin", "gene_name": "NISCH", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAAAAAGEDGEEPLRSARVLGSELVETYTVYIIQVSVGNHQWTVKHRYSDFHDLHEKLVSEKKIDKNLLPPKKIIGKNSKSLVEKRQKELEVYLQTLLVKFSVTAPKVLSHFLHFHFYEINGITAALAEELFHKGEQLLMAGEVFTIRPLQLYAVTQQLLQGKPTCANGDAKTDLGHILDFTCRLKYLKVTGTGGPFGTSNIQEHHLPFDLSIFKSLHQIEINHCGGKLIKGLTSSKHTLATMSVRFSATSMKEILVPEASEFDQWEPEGASASCPVTAVIPTWRNLTTLDMSHNNISQIDDSVKLIPKIEFLDLSHNGVSLVENLQHLYNLVHLDLSYNKLTSLEGVHTKLGNIKTLNLAGNQLESLYGLNKLYSLVNLDLSSNRIEQIDEVKNIGSLPCLEKVVLSSNPLSIIPDYRTKVLAQFGDRASEVCLDNIVTTEKELDTVEVLKAIQKSKEVKYKLSNSDKKISEDFRLTAASSKSNCSSLTVRPSSPSLPRPVSSSQEIVCEETVLASSSFQFNASTPTDHTVPQRCSEIPDSRCKNQAPVSLLEYGRGDNTCLDHPEEERCTVPDPCNTVILPFNCMSYTATNQDFTQHLSALIAQTVQRTTPSFIENKGSLPAGSRTTDKEDGYFEMGLHEGDQTFEFSTSQTQSSDNVAVKSINVVKILWSFSIHIYKEVRQFASCLVLTDDLLAVFEIPPQELRGSCQHIPSALKLILCFPYADLTEFGFLMPEICLMLKLKNSDNCLFVVSDSQNLQDFYSCLHTCHSRHCTSVLPSSTTYCGSANLQEFLSQLMELNCISSEDVEIKGCFPTYLVYGNKTNAQKTLHQPDSAGSNKAWSKDDLRSTLYSSMYKSSDQCPCVFHPCWLFLTTQHLYIIKVDFSVLPNKWIGTEDLRSVLKLNSIPLASVVLHPTHGSIQQKGSFLDGHVLELLIGYRFVTAVFVLPHEKFHFLRVYSLLRTLLKNVKTIIVFKASNKSDAARNHVLESNRHGQSASFYKPHLTLSSLYPSEFLIQKITEDNQIPVHLHASVSLQYVAGLKGNALVEFFHGNIAEVENEELRHLMWSSVLFYKTPSVEVMACVLLSTKAIYFLLDDTFNHADEQQSDFWNQENSDCENNSFHLSCCLVLKLNDLQSVNVGLFDQYFRITGQSADHIVTCLTRDSYNTHAFMQQLMAVLSLLARTPSPEPIDKDFYSEFGSKNTGKMENYELIHSSRVKFIYPNEEEIGDLAFLVAEKMDDLTHLQSLHILLYVLAFQVNPVEGSAQNTSPLQPKTLILTSSDLFLFDEDYICYPLPEFAKEPPKRDKYRLADGRRIRDLDRVLMGYQTYPQALTFVFDDVQNQNLMQNLALNHFGDADSAPKGNAKQEGNRSREIQWYIFIPSAESRERLISLLARQWEILCGRELPLELTG", "length": 1416 }, "evidence": [ { "id": "A0A5G2RKR1", "url": "https://omabrowser.org/oma/group/A0A5G2RKR1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N322-1", "protein_name": "Nischarin", "gene_name": "NISCH", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAARSFGPEREAEPVKTARVVGSELVDTYTVYIIQITDGSHEWTVKHRYSDFHDLHEKLVAEKKIDRSLLPPKKIIGKNSRSLVEKREKDLEIYLQTLLATFPDVAPRVLAQFLHFHFYEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDARRIRGLVASKPTLATMSVRFSATSMKEVLVPEASEFDEWEPAGAALEGPVTAVIPTWQALTALDLSHNSISEIDDSVKLIPKIEFLDLSHNGVLVMNNLQHLYNLVHVDLSYNKLSSLEGAHTKLGNIKTLNLAGNLLRHLSGLHKLYSLVNLDLSDNRIEQMEEVRSIGSLPCLEHVALLNNPLSIIPDYRTKVLAQFGERASEVCLDNTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKVSEDSRLSAAPCVRPSSSPPSAAPTSASLPQPILSNQGIMFVQEDALASSLSSTDSLTPEDRSIVGGCSDSLESIPAGQAPSDDLRDVPGAVGGVSPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEDDEEEEDVAENRYFEMGPPDTEEEEEGGPGEEEEEEEEEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLFIISDAAHLHEFHADLRACFAPQHMAMLCSPVLYGSHTSLQEFLRQLLTFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAPGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRIYNQLRASLQDLKTVVIAKTPATGGGPQSPLVDGQPAESRASSDQNLQEAPAETTAPALVEAPALTPGEASAPSPAKTPAPVEASVPALVPVEVPEEAEASAEIPVEALAQAEAPAQYPSEPLIRSMSEDNQIPSHLPACPSLRHIASLRGRAVVEFFHSSIAEVENEELRHLLWSSVVFYQMPGLEVTACVLLSTKAVYFVLHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQVVNVGLFDQYFRLTGSCPAQVVTCLTRDSYLTHCFLQHLMAVLSLLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYPSEEEVGDLTFTVAQKMAAPEKAPALSILLCVQAFQVGSPQPGRCRGLLRPKTLLLTSAEIFLLDEDFVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHDLMGSVTLDHFGEVPGGPARGGQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVELTG", "length": 1508 }, "evidence": [ { "id": "A0A5G2RKR1", "url": "https://omabrowser.org/oma/group/A0A5G2RKR1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4G017-1", "protein_name": "Nischarin", "gene_name": "Nisch", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAATLSFGPEREAEPAKEARVVGSELVDTYTVYVIQVTDGNHEWTIKHRYSDFHDLHEKLVAERKIDKTLLPPKKIIGKNSRSLVEKREKDLEVYLQTLLKTFPDVAPRVLAHFLHFHLYEINGVTAALAEELFEKGEQLLGAGEVFAIRPLQLYAITEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIREQLLPFDLSIFKSLHQVEMSHCDAKHVRGLVTSKPTLATMSVRFSAASMKEVLVPEASEFDEWEPEGTTLGGPVTAVIPTWQALTTLDLSHNSISEIDESVKLIPKIEYLDLSHNGVLVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNVKTLNLAGNFLERLSGLHKLYSLVNLDLRDNRIEQLDEVKSIGNLPCLEHVALLNNPLSIIPDYRTKVLSQFGERASEICLDDVATTEKELDTVEVLKAIQKAKDVKSKLSSTEKKVGEDFRLPTAPCIRPSSSPPTAVPTSASLPQPILSNQGIMFVQEEALASSLSSTDSLPPDDRPIAQACSNSMGSLPTGQVAAEDLRDLPGAVGGVSPDHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEAHGEQGEEEEEEEEEDVAESRYFEMGPPDAEEEEGSGQGEEDEEDEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTFYKVAGGSQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTSQHLNVIKADFNPMPSRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLKDLKTVVIAKNPSARPRTQGPLAGGQPAKSRVSAEQRLQETPAEAPAPAPAAAESAAEAPAAAEASAPAGAPAPAGAPAPAGAPAGAQAPAPAQAEVPAQYPSERLIQSTSEENQIPSHLPVCPSLQHIARLRGRAIIDLFHSSIAEVENEELRHLLWSSVVFYQTPGLEVTACVLLSTKAVYFILHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQYFRLTGSSPTQVVTCLTRDSYLTHCFLQHLMLVLSSLERTPSPEPIDKDFYSEFGDKNTGKMENYELIHSSRVKFTYPSEEEVGDLTYVVAQKMADPAKNPALSILLYIQAFQVITPQLGRGRGPLRPKTLLLTSAEIFLLDEDYIHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYNPYPQALTLVFDDTQGHDLMGSVTLDHFGEMPGGPGRAGQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVELTG", "length": 1502 }, "evidence": [ { "id": "A0A5G2RKR1", "url": "https://omabrowser.org/oma/group/A0A5G2RKR1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80TM9-1", "protein_name": "Nischarin", "gene_name": "Nisch", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAATLSFGPEREAEPAKEARVVGSELVDTYTVYVIQVTDGNHEWTIKHRYSDFHDLHEKLVAERKIDKSLLPPKKIIGKNSRSLVEKRERDLEVYLQTLLTTFPDVAPRVLAHFLHFHLYEVNGVTAALAEELFEKGEQLLGAGEVFAIRPLQLYAITEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIKEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVTSKPTLATMSVRFSATSMKEVLAPEASEFDEWEPEGTATLGGPVTAIIPTWQALTTLDLSHNSICEIDESVKLIPKIEYLDLSHNGLRVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNVKTLNLAGNFLESLSGLHKLYSLVNVDLRDNRIEQLDEVKSIGSLPCLERLTLLNNPLSIIPDYRTKVLSQFGERASEICLDDVATTEKELDTVEVLKAIQKAKDVKSKLSNTEKKAGEDFRLPPAPCIRPGGSPPAAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLPPEDHRPIARACSDSLESIPAGQVASDDLRDVPGAVGGVSPDHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEAHGEQGEEEEEEEEEEDVAENRYFEMGPPDAEEEEGSGQGEEDEEDEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTTLQEFLRQLLTFYKVAGGSQERSQGCFPVYLVYSDKRMVQTPAGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTSQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVISKNPSAKPRNQPAKSRASAEQRLQETPADAPAPAAVPPTASAPAPAEALAPDLAPVQAPGEDRGLTSAEAPAAAEAPAAAEAPAAAEAPAAAEAPAAAEAPAAAEAPAPAEAPAAAEAPAAAEAPAAAEAPAAAEAPASAEAPAPNQAPAPARGPAPARGPAPAGGPAPAEALAQAEVPAQYPSERLIQSTSEENQIPSHLPVCPSLQHIARLRGRAIIDLFHNSIAEVENEELRHLLWSSVVFYQTPGLEVTACVLLSSKAVYFILHDGLRRYFSEPLQDFWHQKNTDYNNSPFHVSQCFVLKLSDLQSVNVGLFDQYFRLTGSSPTQVVTCLTRDSYLTHCFLQHLMLVLSSLERTPSPEPVDKDFYSEFGDKNTGKMENYELIHSSRVKFTYPSEEEVGDLTYIVAQKMADPAKNPALSILLYIQAFQVVTPHLGRGRGPLRPKTLLLTSAEIFLLDEDYIHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYYPYPQALTLVFDDTQGHDLMGSVTLDHFGEMPGGPGRVGQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVELTG", "length": 1593 }, "evidence": [ { "id": "A0A5G2RKR1", "url": "https://omabrowser.org/oma/group/A0A5G2RKR1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2I1-1", "protein_name": "Nischarin", "gene_name": "NISCH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKLVAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFYEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSVSEIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYRTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLSAAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGCSDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPPDVEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTGGSPQGSFADGQPAERRASNDQRPQEVPAEALAPAPAEVPAPAPAAASASGPAKTPAPAEASTSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGSAIIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLTRDSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYPSEEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEIFLLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHDLMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVELTG", "length": 1504 }, "evidence": [ { "id": "A0A5G2RKR1", "url": "https://omabrowser.org/oma/group/A0A5G2RKR1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1" } ], "pmid": "" }, { "name": "Rac protein signal transduction", "id": "GO:0016601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016601", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1231, "end_pos": 1233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1314, "end_pos": 1316, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RKR1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1520, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RKR1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RKR1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKR1" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 127, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 498, 1088 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1231, "end_pos": 1233 }, { "start_pos": 1314, "end_pos": 1316 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RN95-1", "uniprot_ac": "A0A5G2RN95", "uniprot_id": "A0A5G2RN95_PIG", "mass": { "chemical_mass": 64376.0, "monoisotopic_mass": 64376.0 }, "refseq": {}, "gene_names": [ { "name": "AK5", "type": "recommended", "evidence": [ { "id": "A0A5G2RN95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95" } ] } ], "protein_names": [ { "name": "Adenylate kinase isoenzyme 5", "type": "recommended", "evidence": [ { "id": "A0A5G2RN95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95/entry#names_and_taxonomy" } ] }, { "name": "2.7.4.3", "type": "synonym", "evidence": [ { "id": "A0A5G2RN95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95/entry#names_and_taxonomy" } ] }, { "name": "2.7.4.6", "type": "synonym", "evidence": [ { "id": "A0A5G2RN95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95/entry#names_and_taxonomy" } ] }, { "name": "ATP-AMP transphosphorylase 5", "type": "synonym", "evidence": [ { "id": "A0A5G2RN95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Also displays broad nucleoside diphosphate kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95#function" }, { "database": "UniProtKB", "id": "ARBA00053658", "url": "https://www.uniprot.org/uniprotkb/ARBA00053658#function" }, { "database": "UniProtKB", "id": "A0A8W4FCW1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCW1#function" }, { "database": "UniProtKB", "id": "F1S9R3", "url": "https://www.uniprot.org/uniprotkb/F1S9R3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AK5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95", "locus": { "chromosome": "6", "start_pos": 135745881, "end_pos": 136020541, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003773", "url": "https://www.ensembl.org/id/ENSSSCG00000003773" } ] } } ], "crossref": [ { "id": "A0A5G2RN95", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RN95", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003773", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003773", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01428", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01428", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22978", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22978", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "733697", "url": "https://www.ncbi.nlm.nih.gov/gene/733697", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ETHIVHQ", "url": "https://omabrowser.org/oma/group/ETHIVHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00406", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00406", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-499943", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-499943", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "12973", "url": "https://www.rhea-db.org/rhea/12973", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "18113", "url": "https://www.rhea-db.org/rhea/18113", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44640", "url": "https://www.rhea-db.org/rhea/44640", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AJJ9", "url": "https://www.uniprot.org/uniprotkb/A0A287AJJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AJJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RN95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RN95-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCW1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S9R3", "url": "https://www.uniprot.org/uniprotkb/F1S9R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S9R3-1", "url": "https://www.uniprot.org/uniprotkb/F1S9R3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWTSRVGCRQRPAAVSGNEVQARGGGMLSPASLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQMPDEVGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDSKLFPNKEAAAGSSDLDPSIMLDTGEIIDTGSDYEDQSIFLASNFSYSYFKGFMEELRKCKIIFMIGGPGSGKGTQCEKLGEKYGLTHLSTDKLLRNELSSESERSKLIRDVMERGELVPSGIILELLKEAMVANLSNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRRQSSPCADEDTTTIAKRLETYYRASIPVVAYYETKTQLHKINAEGTPEEVFLQLCSAIDSIF", "length": 573, "header": "tr|A0A5G2RN95-1|A0A5G2RN95_PIG Isoform 1 of Adenylate kinase isoenzyme 5 OS=Sus scrofa OX=9823 GN=AK5 PE=1 SV=2 CANONICAL=A0A5G2RN95-1" }, "isoforms": [ { "isoform_ac": "A0A287AJJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95/entry#A0A287AJJ9-1", "sequence": { "sequence": "MNTNDAKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQMPDEVGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLMNFKQNAAPLVKYFQEKGLIMTGDDQLPVFGEDTMEGFMEELRKCKIIFMIGGPGSGKGTQCEKLGEKYGLTHLSTDKLLRNELSSESERSKLIRDVMERGELVPSGIILELLKEAMVANLSNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRRQSSPCADEDTTTIAKRLETYYRASIPVVAYYETKTQLHKINAEGTPEEVFLQLCSAIDSIF", "length": 506, "header": "tr|A0A287AJJ9-1|A0A5G2RN95_PIG Computationally mapped isoform of Adenylate kinase isoenzyme 5 OS=Sus scrofa OX=9823 GN=AK5 PE=1 SV=1 CANONICAL=A0A5G2RN95-1" }, "locus": { "chromosome": "6", "start_pos": 136020184, "end_pos": 135747150, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056587.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056587.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044186.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044186.1" } ] } }, { "isoform_ac": "A0A5G2RN95-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95/entry#A0A5G2RN95-1", "sequence": { "sequence": "MWTSRVGCRQRPAAVSGNEVQARGGGMLSPASLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQMPDEVGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDSKLFPNKEAAAGSSDLDPSIMLDTGEIIDTGSDYEDQSIFLASNFSYSYFKGFMEELRKCKIIFMIGGPGSGKGTQCEKLGEKYGLTHLSTDKLLRNELSSESERSKLIRDVMERGELVPSGIILELLKEAMVANLSNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRRQSSPCADEDTTTIAKRLETYYRASIPVVAYYETKTQLHKINAEGTPEEVFLQLCSAIDSIF", "length": 573, "header": "tr|A0A5G2RN95-1|A0A5G2RN95_PIG Isoform 1 of Adenylate kinase isoenzyme 5 OS=Sus scrofa OX=9823 GN=AK5 PE=1 SV=2 CANONICAL=A0A5G2RN95-1" }, "locus": { "chromosome": "6", "start_pos": 136019844, "end_pos": 135747150, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069526.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069526.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074265.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074265.2" } ] } }, { "isoform_ac": "A0A8W4FCW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95/entry#A0A8W4FCW1-1", "sequence": { "sequence": "MNTNDAKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQMPDEVGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDSKLFPNKEAAAGSSDLDPSIMLDTGEIIDTGSDYEDQSIFLASNFSYSYFKGFMEELRKCKIIFMIGGPGSGKGTQCEKLGEKYGLTHLSTDKLLRNELSSESERSKLIRDVMERGELVPSGIILELLKEAMVANLSNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRRQSSPCADEDTTTIAKRLETYYRASIPVVAYYETKTQLHKINAEGTPEEVFLQLCSAIDSIF", "length": 538, "header": "tr|A0A8W4FCW1-1|A0A5G2RN95_PIG Computationally mapped isoform of Adenylate kinase isoenzyme 5 OS=Sus scrofa OX=9823 GN=AK5 PE=1 SV=1 CANONICAL=A0A5G2RN95-1" }, "locus": { "chromosome": "6", "start_pos": 136020184, "end_pos": 135747150, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098213.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098213.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077156.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077156.1" } ] } }, { "isoform_ac": "F1S9R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95/entry#F1S9R3-1", "sequence": { "sequence": "MNTNDAKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQMPDEVGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDSKLFPNKEAAAGSSDLDPSIMLDTGEIIDTGSDYEDQGDDQLPVFGEDTMEGFMEELRKCKIIFMIGGPGSGKGTQCEKLGEKYGLTHLSTDKLLRNELSSESERSKLIRDVMERGELVPSGIILELLKEAMVANLSNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRRQSSPCADEDTTTIAKRLETYYRASIPVVAYYETKTQLHKINAEGTPEEVFLQLCSAIDSIF", "length": 538, "header": "tr|F1S9R3-1|A0A5G2RN95_PIG Computationally mapped isoform of Adenylate kinase isoenzyme 5 OS=Sus scrofa OX=9823 GN=AK5 PE=1 SV=4 CANONICAL=A0A5G2RN95-1" }, "locus": { "chromosome": "6", "start_pos": 136020184, "end_pos": 135747150, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004175.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004175.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004081.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004081.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S9R3", "url": "https://www.uniprot.org/uniprotkb/F1S9R3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-499943", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-499943", "resource": "Reactome", "description": "Interconversion of nucleotide di- and triphosphates" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZN35-1", "protein_name": "Adenylate kinase isoenzyme 5", "gene_name": "AK5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTGHRAWLHSADTLKMGMLEQEMQIKLFFYTGVRLVLAIYSNGAHLQKYMASCCGRSLLNGLMCYKPDDPIEYLESCLQKVKELGGSEKVKWDTFVSPEKKALPPLNGGQSRRSFFRNVMPDNSNFPYRRYDRLPPIQQFSIESDTDLSETAELIEEYDVFDPARPRPKIILVIGGPGSGKGTQSLKIAERYGFNYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQRLMQIPDEEGIVIDGFPRDVAQAISFEDQICTPDLVVFLACSNQRLKERLLKRAEQQGRPDDNLKATQRRLMNFKQNAVPLVKYFQEKGLIVTFDADRDEEEVFSDISSAVDNKLFANKEAAAGTNELDCSLIMDSGDTAYTEFDFEDQEEDQSSFSGYESTGDFSEDLKKSNIFFIVGGPGSGKSSQCEQLAKKYGFTHLSTANLLQNELSSLSERSKFIKDIMECGEPVPGGIVLELLKEAMITNLGDTKGFLIDGYPCELKEAEEFESKIGEPKLVFCLDCSAETMNSRYLMRNQTSQHFDSAETIKEGIEGYCQAAKPLTAYYERKTQLCKVDAEGTAEDVFLDVCKSIDSFLKKEEAAFSTETQ", "length": 609 }, "evidence": [ { "id": "A0A5G2RN95", "url": "https://omabrowser.org/oma/group/A0A5G2RN95/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A4IFD0-1", "protein_name": "Adenylate kinase isoenzyme 5", "gene_name": "Ak5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNTNEAKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQMPDEVGIVIDGFPRDVAQALSFEDQICTPDLVVFLACTNQRLKERLLKRAEQQGRPDDNLKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDSKLFPNKEAAAGSSDLDPSMMLDTGEVIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLKKCKIIFMIGGPGSGKGTQCGKLAEKYGFTHLSTDELLQNELSSESGRSKLIRDIMERGELVPSGIILELLKEAMVASLSNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRSRNSPQADDNTTTIAKRLETYYRASIPVVAYYETKTQLHKINAEGTPEEVFLQLCTAIDSIF", "length": 562 }, "evidence": [ { "id": "A0A5G2RN95", "url": "https://omabrowser.org/oma/group/A0A5G2RN95/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A5PMF1-1", "protein_name": "Adenylate kinase isoenzyme 5", "gene_name": "ak5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNTNDAKEYLSRREIPQLFESLLTGLMYYRPDDPLEYLETCLKKVRDLGGTDKVRWDTFVGQEKKSLPPLNGGQSRRSFFRNVLPDSPNFPYRRYERLPPINQFSIESDSDLSETAELIEEYEVFDPSRPRPKVILIIGGPGSGKGTQCLKIAERYGFEYVSVGELLRKKMIHNATSNRKWSLIARIITNGELAPQETTITEIKQKIMKIPEASGIVIDGFPRDVGQALSFEDQVCTPDLVVFLACSNQRLKERLEKRAEQQGRPDDNPKAIDRRLTNFKQNAIPLVKYFQEKGLIVTLDADRDEEEVFYDISMTVDNKLFPTKEPVAGPSELDLSLIADSSSLTDVPAKFDEQADEEVAEYAEAIGESFPMETKKSKVIFVIGGPGSGKALQSEKIEERYSLKRLCPGDILCSELQSHSERGRFLRDLLERGEQLPEDTLLDLLCEAMASTVRQGKGFLVTGFPKNEKQAQEYEAKMGQPDIVLLLECSADIMSRRLQQRATCSLHSKEARDRDTRRRVDGFCSLINPVVAHYQHREFFHKIDAEQPPEDVFEHICVVLDSC", "length": 563 }, "evidence": [ { "id": "A0A5G2RN95", "url": "https://omabrowser.org/oma/group/A0A5G2RN95/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0R7U1-1", "protein_name": "Adenylate kinase isoenzyme 5", "gene_name": "Ak5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTNEAKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPSRPRPKIILVIGGPGSGKGTQSLKIAERYGFQCISVGELLRKKIHSASSNRKWSLIAKIITNGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDISMAVDNKLFPNKEAPTDSSDLDPSMMFDAGEIVDTGSDYDNQDDDQLNVFGEDTMGGFVEDLRKCKIIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRIGEPQLVICMDCSADTMTNRLLQRSQSSQRGEDSAKSVAKRLEAYHRASIPVIAYYETKTQLQKVNAEGTPDQVFLQLCTAIDSVF", "length": 562 }, "evidence": [ { "id": "A0A5G2RN95", "url": "https://omabrowser.org/oma/group/A0A5G2RN95/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q920P5-1", "protein_name": "Adenylate kinase isoenzyme 5", "gene_name": "Ak5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTNDAKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKWSLIAKIITNGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDISVAVDSKLFPNKEAPMDSSDLDPSMMFDAGEIIDTGSDYDNQDDDQLNVFGEDTEGGFMEDLRKCKIIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQLRKVNAEGTPEQVFLQLCTAIDSVF", "length": 562 }, "evidence": [ { "id": "A0A5G2RN95", "url": "https://omabrowser.org/oma/group/A0A5G2RN95/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6K8-1", "protein_name": "Adenylate kinase isoenzyme 5", "gene_name": "AK5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNTNDAKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF", "length": 562 }, "evidence": [ { "id": "A0A5G2RN95", "url": "https://omabrowser.org/oma/group/A0A5G2RN95/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "AMP kinase activity", "id": "GO:0004017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95" } ], "pmid": "" }, { "name": "nucleoside diphosphate kinase activity", "id": "GO:0004550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004550", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ATP metabolic process", "id": "GO:0046034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046034", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12973", "name": "", "equation": "AMP + ATP = 2 ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12973", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12973" } ] }, { "id": "18113", "name": "", "equation": "a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "18113", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18113" } ] }, { "id": "44640", "name": "", "equation": "a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "44640", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44640" } ] }, { "id": "R-SSC-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-110137", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110137" } ] }, { "id": "R-SSC-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-110138", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110138" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RN95-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 573, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RN95-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RN95" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 371, "end_pos": 373 }, { "start_pos": 462, "end_pos": 464 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1TVR4-1", "uniprot_ac": "A0A5K1TVR4", "uniprot_id": "A0A5K1TVR4_PIG", "mass": { "chemical_mass": 160635.0, "monoisotopic_mass": 160635.0 }, "refseq": {}, "gene_names": [ { "name": "SETD5", "type": "recommended", "evidence": [ { "id": "A0A5K1TVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ] } ], "protein_names": [ { "name": "SET domain containing 5", "type": "synonym", "evidence": [ { "id": "A0A5K1TVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SETD5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4", "locus": { "chromosome": "13", "start_pos": 65850506, "end_pos": 65759987, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011540", "url": "https://www.ensembl.org/id/ENSSSCG00000011540" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011540", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011540", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19181", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19181", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46462", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46462", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46462:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46462:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AQU6", "url": "https://www.uniprot.org/uniprotkb/A0A287AQU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AQU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1TVR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F7J2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F7J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7J2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSIAIPLGVTTPDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYADHNYGAPPPPTPPASPPVQTIIPRSDLNGLPSPVEERCGDSPNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKRKKSPEKGRAAPKTKKIKAFREGSRKSLRMKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPAILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNAAELPLPPPPSLPTIGAETRRRKARRKELEMEQQNEAPEEDNNQQPEQIPEKVTVSSDHEEIDNPEEKVEEKEEVIDDQENPAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSSSDIEVTTSTSETPMGEETKNEAPESEVSNPVSNIAIPSNPQSVGVNTRRSSQAGDVAAEKPVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQAIAQQAELSQAALEEGATNSSVTPTEAGNVDSSGENRQLTGSDPTVVSVTGSHVNRATSKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSNSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNPGSKSPQLTTPGPSHPEEECRNGYSLMFSPITSLTTASRCNTPLQFELCHRKDLDLTKVGYLDSNTNSCADRPSLINSGHSDLAPHPSVGPTSETSFASRTGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFPSRYEHGFMKDLSRGSMSPGGERACDGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSLSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPTDGEGPETLSSALSKGAAVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYYSSQPHSGNSTGSSLPRRSCPSSAASPTPQGPSDSPTSDSVSQSSTGTLSSTSFAQNSRSSLPSDFRTISLPSAGQSAAYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS", "length": 1469, "header": "tr|A0A5K1TVR4-1|A0A5K1TVR4_PIG Isoform 1 of SET domain containing 5 OS=Sus scrofa OX=9823 GN=SETD5 PE=4 SV=2 CANONICAL=A0A5K1TVR4-1" }, "isoforms": [ { "isoform_ac": "A0A287AQU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4/entry#A0A287AQU6-1", "sequence": { "sequence": "MSIAIPLGVTTPDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYATIIPRSDLNGLPSPVEERCGDSPNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKRKKSPEKGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPAILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNAAELPLPPPPSLPTIGAETRRRKARRKELEMEQQNEAPEEDNNQQPEQIPEKVTVSSDHEEIDNPEEKVEEKEEVIDDQENPAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSSSDIEVTTSTSETPMGEETKNEAPESEVSNPVSNIAIPSNPQSVGVNTRRSSQAGDVAAEKPVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQAIAQQAELSQAALEEGATNSSVTPTEAGNVDSSGENRQLTGSDPTVVSVTGSHVNRATSKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSNSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNPGSKSPQLTTPGPSHPEEECRNGYSLMFSPITSLTTASRCNTPLQFELCHRKDLDLTKVGYLDSNTNSCADRPSLINSGHSDLAPHPSVGPTSETSFASRTGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFPSRYEHGFMKDLSRGSMSPGGERACDGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSLSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPTDGEGPETLSSALSKGAAVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYYSSQPHSGNSTGSSLPRRSCPSSAASPTPQGPSDSPTSDSVSQSSTGTLSSTSFAQNSRSSLPSDFRTISLPSAGQSAAYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS", "length": 1437, "header": "tr|A0A287AQU6-1|A0A5K1TVR4_PIG Computationally mapped isoform of SET domain containing 5 OS=Sus scrofa OX=9823 GN=SETD5 PE=4 SV=2 CANONICAL=A0A5K1TVR4-1" }, "locus": { "chromosome": "13", "start_pos": 65850144, "end_pos": 65802924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048743.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048743.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046429.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046429.2" } ] } }, { "isoform_ac": "A0A5K1TVR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4/entry#A0A5K1TVR4-1", "sequence": { "sequence": "MSIAIPLGVTTPDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYADHNYGAPPPPTPPASPPVQTIIPRSDLNGLPSPVEERCGDSPNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKRKKSPEKGRAAPKTKKIKAFREGSRKSLRMKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPAILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNAAELPLPPPPSLPTIGAETRRRKARRKELEMEQQNEAPEEDNNQQPEQIPEKVTVSSDHEEIDNPEEKVEEKEEVIDDQENPAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSSSDIEVTTSTSETPMGEETKNEAPESEVSNPVSNIAIPSNPQSVGVNTRRSSQAGDVAAEKPVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQAIAQQAELSQAALEEGATNSSVTPTEAGNVDSSGENRQLTGSDPTVVSVTGSHVNRATSKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSNSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNPGSKSPQLTTPGPSHPEEECRNGYSLMFSPITSLTTASRCNTPLQFELCHRKDLDLTKVGYLDSNTNSCADRPSLINSGHSDLAPHPSVGPTSETSFASRTGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFPSRYEHGFMKDLSRGSMSPGGERACDGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSLSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPTDGEGPETLSSALSKGAAVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYYSSQPHSGNSTGSSLPRRSCPSSAASPTPQGPSDSPTSDSVSQSSTGTLSSTSFAQNSRSSLPSDFRTISLPSAGQSAAYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS", "length": 1469, "header": "tr|A0A5K1TVR4-1|A0A5K1TVR4_PIG Isoform 1 of SET domain containing 5 OS=Sus scrofa OX=9823 GN=SETD5 PE=4 SV=2 CANONICAL=A0A5K1TVR4-1" }, "locus": { "chromosome": "13", "start_pos": 65850144, "end_pos": 65802924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012635.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012635.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012303.5", "url": "https://www.ensembl.org/id/ENSSSCP00000012303.5" } ] } }, { "isoform_ac": "A0A8W4F7J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4/entry#A0A8W4F7J2-1", "sequence": { "sequence": "MSIAIPLGVTTPDTSYSDMAAGSEKEVEAPYLSRRSGTTPGCESPAKETQGA", "length": 52, "header": "tr|A0A8W4F7J2-1|A0A5K1TVR4_PIG Computationally mapped isoform of SET domain containing 5 OS=Sus scrofa OX=9823 GN=SETD5 PE=4 SV=1 CANONICAL=A0A5K1TVR4-1" }, "locus": { "chromosome": "13", "start_pos": 65803889, "end_pos": 65802924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099342.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099342.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075273.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075273.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1344, "start_aa": "Thr", "end_pos": 1344, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1344", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1375, "start_aa": "Thr", "end_pos": 1375, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1375", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 70, "start_aa": "Thr", "end_pos": 70, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr70", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 884, "start_aa": "Thr", "end_pos": 884, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr884", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 981, "start_aa": "Thr", "end_pos": 981, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr981", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F7J2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7J2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "Set3 complex", "id": "GO:0034967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034967", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "Rpd3L-Expanded complex", "id": "GO:0070210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070210", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "cognition", "id": "GO:0050890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050890", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription elongation", "id": "GO:0032784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032784", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase III", "id": "GO:0016480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016480", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "regulation of chromatin organization", "id": "GO:1902275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902275", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "histone H3K36 methyltransferase activity", "id": "GO:0046975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046975", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" }, { "name": "histone H3K9 methyltransferase activity", "id": "GO:0046974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046974", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TVR4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1188, "end_pos": 1190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1231, "end_pos": 1233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1356, "end_pos": 1358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 683, "end_pos": 685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 845, "end_pos": 847, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1TVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TVR4" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 300, "end_pos": 421, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 70, 884, 981, 1344, 1375 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1188, "end_pos": 1190 }, { "start_pos": 1231, "end_pos": 1233 }, { "start_pos": 1356, "end_pos": 1358 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 683, "end_pos": 685 }, { "start_pos": 845, "end_pos": 847 }, { "start_pos": 872, "end_pos": 874 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1ULP5-1", "uniprot_ac": "A0A5K1ULP5", "uniprot_id": "A0A5K1ULP5_PIG", "mass": { "chemical_mass": 49958.0, "monoisotopic_mass": 49958.0 }, "refseq": {}, "gene_names": [ { "name": "COPS2", "type": "recommended", "evidence": [ { "id": "A0A5K1ULP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5" } ] } ], "protein_names": [ { "name": "COP9 signalosome complex subunit 2", "type": "recommended", "evidence": [ { "id": "A0A5K1ULP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5/entry#names_and_taxonomy" } ] }, { "name": "Alien homolog", "type": "synonym", "evidence": [ { "id": "A0A5K1ULP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5/entry#names_and_taxonomy" } ] }, { "name": "JAB1-containing signalosome subunit 2", "type": "synonym", "evidence": [ { "id": "A0A5K1ULP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5/entry#names_and_taxonomy" } ] }, { "name": "Thyroid receptor-interacting protein 15", "type": "synonym", "evidence": [ { "id": "A0A5K1ULP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1ULP5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5#function" }, { "database": "UniProtKB", "id": "ARBA00058166", "url": "https://www.uniprot.org/uniprotkb/ARBA00058166#function" }, { "database": "UniProtKB", "id": "A0A4X1SLP6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLP6#function" }, { "database": "UniProtKB", "id": "A0A4X1SN00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN00#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1ULP5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "COPS2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5", "locus": { "chromosome": "1", "start_pos": 122578858, "end_pos": 122542387, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004652", "url": "https://www.ensembl.org/id/ENSSSCG00000004652" } ] } } ], "crossref": [ { "id": "A0A5K1ULP5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1ULP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004652", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004652", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01399", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01399", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25983", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25983", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6781823", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6781823", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013422", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013422", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SLP6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SLP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SN00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SN00-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1ULP5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1ULP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "length": 428, "header": "tr|A0A5K1ULP5-1|A0A5K1ULP5_PIG Isoform 1 of COP9 signalosome complex subunit 2 OS=Sus scrofa OX=9823 GN=COPS2 PE=1 SV=2 CANONICAL=A0A5K1ULP5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SLP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5/entry#A0A4X1SLP6-1", "sequence": { "sequence": "MVISYKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "length": 393, "header": "tr|A0A4X1SLP6-1|A0A4X1SLP6_PIG Computationally mapped isoform of COP9 signalosome complex subunit 2 OS=Sus scrofa OX=9823 GN=COPS2 PE=1 SV=1 CANONICAL=A0A5K1ULP5-1" }, "locus": { "chromosome": "1", "start_pos": 122572680, "end_pos": 122556795, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067634.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067634.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067379.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067379.2" } ] } }, { "isoform_ac": "A0A4X1SN00-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5/entry#A0A4X1SN00-1", "sequence": { "sequence": "MSDMEDDFMCDDEEDYDLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "length": 379, "header": "tr|A0A4X1SN00-1|A0A4X1SN00_PIG Computationally mapped isoform of COP9 signalosome complex subunit 2 OS=Sus scrofa OX=9823 GN=COPS2 PE=1 SV=1 CANONICAL=A0A5K1ULP5-1" }, "locus": { "chromosome": "1", "start_pos": 122572680, "end_pos": 122542427, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079932.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079932.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074256.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074256.1" } ] } }, { "isoform_ac": "A0A5K1ULP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5/entry#A0A5K1ULP5-1", "sequence": { "sequence": "MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "length": 428, "header": "tr|A0A5K1ULP5-1|A0A5K1ULP5_PIG Isoform 1 of COP9 signalosome complex subunit 2 OS=Sus scrofa OX=9823 GN=COPS2 PE=1 SV=2 CANONICAL=A0A5K1ULP5-1" }, "locus": { "chromosome": "1", "start_pos": 122572680, "end_pos": 122542427, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005137.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005137.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005012.5", "url": "https://www.ensembl.org/id/ENSSSCP00000005012.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1ULP5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6781823", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6781823", "resource": "Reactome", "description": "Formation of TC-NER Pre-Incision Complex" }, { "id": "R-SSC-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-SSC-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-SSC-9013422", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013422", "resource": "Reactome", "description": "RHOBTB1 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1ULP5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5" } ], "pmid": "" }, { "name": "COP9 signalosome", "id": "GO:0008180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008180", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1ULP5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1ULP5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1ULP5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein deneddylation", "id": "GO:0000338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000338", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1ULP5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1ULP5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 428, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1ULP5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1ULP5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1ULP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1ULP5" }, { "id": "PS50250", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50250" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PCI", "eco_id": "ECO_0000259", "start_pos": 254, "end_pos": 428, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 333, "end_pos": 335 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RHG3-1", "uniprot_ac": "A0A5G2RHG3", "uniprot_id": "A0A5G2RHG3_PIG", "mass": { "chemical_mass": 40234.0, "monoisotopic_mass": 40234.0 }, "refseq": { "ac": "NP_001230295", "name": "kinetochore-associated protein DSN1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230295" }, "gene_names": [ { "name": "DSN1", "type": "recommended", "evidence": [ { "id": "A0A5G2RHG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3" } ] }, { "name": "DSN1", "type": "synonym", "evidence": [ { "id": "NP_001230295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230295" } ] } ], "protein_names": [ { "name": "DSN1 component of MIS12 kinetochore complex", "type": "synonym", "evidence": [ { "id": "A0A5G2RHG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3/entry#names_and_taxonomy" } ] }, { "name": "DSN1 homolog, MIS12 kinetochore complex component", "type": "synonym", "evidence": [ { "id": "NP_001230295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230295" } ] }, { "name": "DSN1, MIND kinetochore complex component, homolog", "type": "synonym", "evidence": [ { "id": "NP_001230295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230295" } ] }, { "name": "kinetochore-associated protein DSN1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001230295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230295" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DSN1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3", "locus": { "chromosome": "17", "start_pos": 39990624, "end_pos": 40017365, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007323", "url": "https://www.ensembl.org/id/ENSSSCG00000007323" } ] } } ], "crossref": [ { "id": "ENSSSCG00000007323", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007323", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152867", "url": "https://www.ncbi.nlm.nih.gov/gene/100152867", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013218", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013218", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152867", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152867", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDKSQSW", "url": "https://omabrowser.org/oma/group/QDKSQSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QDW2", "url": "https://www.orthodb.org/?gene=A0A5G2QDW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RHG3", "url": "https://www.orthodb.org/?gene=A0A5G2RHG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1S478", "url": "https://www.orthodb.org/?gene=F1S478", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14778", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14778", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14778:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14778:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68877", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230295", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230295", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QDW2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QDW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RHG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RHG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S478", "url": "https://www.uniprot.org/uniprotkb/F1S478", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S478-1", "url": "https://www.uniprot.org/uniprotkb/F1S478-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSGSEIVEVLEEEPVTSKTHDHQLESDPNTVEACSKPPASLEMTEGVSEEQIHLGSSPKRGGSCDLSYQEGLQARPFHLSPQEQSAHRQDRRQSWRRASMKETNRRKSLPPFHQGITELCRCISVNVAESKRLGSLLLSSFQFSVQKLEPFLRGTEGFNLENFRAKASSISEELKHFADRLESNGTLQKCFEDSEGRASDLSLEASVAEMKEYITKFSLERQSWDQLLLHYQEEAKEITSRGSTETKTKNTEVEVEPTTYLGSSQSEVLNTKPDYQKILQNQNKVFDCMELVMDELQGSVKQLHAFMDESTQCLQKVSVQLGKRSTQQLDSSPARKLLKLQPREQPTAHCSKSCQ", "length": 356, "header": "tr|A0A5G2RHG3-1|A0A5G2RHG3_PIG Isoform 1 of DSN1 component of MIS12 kinetochore complex OS=Sus scrofa OX=9823 GN=DSN1 PE=4 SV=1 CANONICAL=A0A5G2RHG3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QDW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3/entry#A0A5G2QDW2-1", "sequence": { "sequence": "MTSGSEIVEELCRCISVNVAESKRLGSLLLSSFQFSVQKLEPFLRGTEGFNLENFRAKASSISEELKHFADRLESNGTLQKCFEDSEGRASDLSLEASVAEMKEYITKFSLERQSWDQLLLHYQEEAKEITSRGSTETKTKNTEVEVEPTTYLGSSQSEVLNTKPDYQKILQNQNKVFDCMELVMDELQGSVKQLHAFMDESTQCLQKVSVQLGKRSTQQLDSSPARKLLKLQPREQPTAHCSKSCQ", "length": 247, "header": "tr|A0A5G2QDW2-1|A0A5G2RHG3_PIG Computationally mapped isoform of DSN1 component of MIS12 kinetochore complex OS=Sus scrofa OX=9823 GN=DSN1 PE=4 SV=1 CANONICAL=A0A5G2RHG3-1" }, "locus": { "chromosome": "17", "start_pos": 40015676, "end_pos": 39996695, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079133.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079133.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061827.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061827.1" } ] } }, { "isoform_ac": "A0A5G2RHG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3/entry#A0A5G2RHG3-1", "sequence": { "sequence": "MTSGSEIVEVLEEEPVTSKTHDHQLESDPNTVEACSKPPASLEMTEGVSEEQIHLGSSPKRGGSCDLSYQEGLQARPFHLSPQEQSAHRQDRRQSWRRASMKETNRRKSLPPFHQGITELCRCISVNVAESKRLGSLLLSSFQFSVQKLEPFLRGTEGFNLENFRAKASSISEELKHFADRLESNGTLQKCFEDSEGRASDLSLEASVAEMKEYITKFSLERQSWDQLLLHYQEEAKEITSRGSTETKTKNTEVEVEPTTYLGSSQSEVLNTKPDYQKILQNQNKVFDCMELVMDELQGSVKQLHAFMDESTQCLQKVSVQLGKRSTQQLDSSPARKLLKLQPREQPTAHCSKSCQ", "length": 356, "header": "tr|A0A5G2RHG3-1|A0A5G2RHG3_PIG Isoform 1 of DSN1 component of MIS12 kinetochore complex OS=Sus scrofa OX=9823 GN=DSN1 PE=4 SV=1 CANONICAL=A0A5G2RHG3-1" }, "locus": { "chromosome": "17", "start_pos": 40015676, "end_pos": 39996695, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086223.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086223.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070786.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070786.1" } ] } }, { "isoform_ac": "F1S478-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3/entry#F1S478-1", "sequence": { "sequence": "MTSGSEIVEVLEEEPVTSKTHDHQLESDPNTVEACSKPPASLEMTEGVSEEQIHLGSSPKRGGSCDLSYQEGLQARPFHLSPQEQSAHRQDRRQSWRRASMKETNRRKSLPPFHQGITELCRCISVNVAESKRLGSLLLSSFQFSVQKLEPFLRGTEGFNLENFRAKASSISEELKHFADRLESNGTLQKCFEDSEGASDLSLEASVAEMKEYITKFSLERQSWDQLLLHYQEEAKEITSRGSTETKTKNTEVEVEPTTYLGSSQSEVLNTKPDYQKILQNQNKVFDCMELVMDELQGSVKQLHAFMDESTQCLQKVSVQLGKRSTQQLDSSPARKLLKLQPREQPTAHCSKSCQ", "length": 355, "header": "tr|F1S478-1|A0A5G2RHG3_PIG Computationally mapped isoform of DSN1 component of MIS12 kinetochore complex OS=Sus scrofa OX=9823 GN=DSN1 PE=4 SV=2 CANONICAL=A0A5G2RHG3-1" }, "locus": { "chromosome": "17", "start_pos": 40015676, "end_pos": 39996695, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008013.5", "url": "https://www.ensembl.org/id/ENSSSCT00000008013.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007799.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007799.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QDW2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDW2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152867", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152867", "resource": "KEGG Pathway" }, { "id": "R-SSC-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-SSC-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-SSC-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-68877", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "resource": "Reactome", "description": "Mitotic Prometaphase" }, { "id": "R-SSC-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AC58I7N7-1", "protein_name": "Kinetochore-associated protein DSN1 homolog isoform X1", "gene_name": "dsn1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKRSITALCFKHRNPKSHRGGNEGGRVLSVDARALKENGGASESRRLRDASEGSHGVKRPHDSNHVSGPPQKSPCTSPAPAAMQRLEDDEQPENKVEEESVSVPAAEQNPRSRRKSLRRSSRGRRSLPAFSSSSQPLCETISLSLPDDERLEMLMKAAMQRTVQRVKSSLYTIPGVDTETLQTQVESLHEEWDSLAKDISREAQNSLQPAESDPIVNMTTARIQEDISRLQAECSSWEALLDKHRSKADELNKCVERGEDTGVPLNPSCFAKSSQSQLILNKPDYKTVLTRQQKLLQNMELVMDSQCCIMRDLLSFHEKSQLLLKETSARLASSAGFKDLPSSPIRQLVKAHISSVSS", "length": 358 }, "evidence": [ { "id": "A0A5G2RHG3", "url": "https://omabrowser.org/oma/group/A0A5G2RHG3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CYC5-1", "protein_name": "Kinetochore-associated protein DSN1 homolog", "gene_name": "Dsn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSVTRSEDQEPTMSETQDRPLQPSLKPLEALPQSSAYQEMMTQGVSEEKNHLGSNPGEGESCGADHQEGSQLRSFHLSPQEQSIRPQDRRQSWRRASMKEVNRRKSLAPFHPGITELCRSISVKLAQSQRLGALLLSSFQFSVEKLEPFLKNTKDFSLECFRAKASSLSEELKHFTDRLGNDGTLQKCFVEDSKEKAADFSLEASVAEVKEYITKFSLERQAWDRLLLQYQNEVPPEEMPRGSTETRITEVKVDPAAYLRSSQKEVLSTKPDYQRIVQDQNQVFAYVELVMDELQGSVKQLQALMDESTQYLQKVSVQLKKRSMDQLDSSPARKLLKLPLQSSPSTQ", "length": 348 }, "evidence": [ { "id": "A0A5G2RHG3", "url": "https://omabrowser.org/oma/group/A0A5G2RHG3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H410-1", "protein_name": "Kinetochore-associated protein DSN1 homolog", "gene_name": "DSN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSVTRSEIIDEKGPVMSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ", "length": 356 }, "evidence": [ { "id": "A0A5G2RHG3", "url": "https://omabrowser.org/oma/group/A0A5G2RHG3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "MIS12/MIND type complex", "id": "GO:0000444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000444", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHG3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RMW1-1", "uniprot_ac": "A0A5G2RMW1", "uniprot_id": "A0A5G2RMW1_PIG", "mass": { "chemical_mass": 95366.0, "monoisotopic_mass": 95366.0 }, "refseq": {}, "gene_names": [ { "name": "MYRIP", "type": "recommended", "evidence": [ { "id": "A0A5G2RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ] } ], "protein_names": [ { "name": "Myosin VIIA and Rab interacting protein", "type": "synonym", "evidence": [ { "id": "A0A5G2RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MYRIP", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1", "locus": { "chromosome": "13", "start_pos": 24556735, "end_pos": 24347660, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011269", "url": "https://www.ensembl.org/id/ENSSSCG00000011269" } ] } } ], "crossref": [ { "id": "A0A5G2RMW1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RMW1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011269", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011269", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14555", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14555", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14555:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14555:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02318", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02318", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9824585", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9824585", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QQ36", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ36-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1V5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJQ8", "url": "https://www.uniprot.org/uniprotkb/F1SJQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJQ8-1", "url": "https://www.uniprot.org/uniprotkb/F1SJQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRKLDLSGLTDDETEHVLQVVQRDFNLRKKEEERLSEMKQKLDEEGSKCSILSKHQNFVEHCCMRCCSPFTFLVNTKRRCGDCKFNVCKSCCSYQKHEKVWICCVCQQARVLRTQSLEWFYSNVKSRFKRFGSAKVLKNLYRKHRLESGVCFDILGGSFFEATLENEGSISGSDSTFYRQSEGHSMMDTLAVALRVAEEAIEEAISKAEAYGDSLDKQNEASYLRDHKEELTEELATTILQKIIRKQKNKSEQRMEEEPEWPQPQSCSTKAADEGTTAFPGSHQASTTLWRSQSAFSLSREDALRTSSLEAASRQPKDQQPREEAALPNWKSVDRLDETSAAPVLQSPDGNWMALKDGALPPTRLLVKPKSGTFQALEAASSVASAYDEMGSDSEEDFDWREALSTLCPQPQGLPRHPQPQPMQVQGSDQGPSAASASSGLSPNPEAMCSDSETSSAGSSREAGHQARLSWLQRKAPRNPVAEKMRLQGELDVNFNPQAASRETSDSSEPEEAPHAADRRAKRWRRARGGSEEPSKELSSPNAHPPEGDTHQVSGDLSETDISSEARHRRSSTDTSEQKLRNRLYELAMKMSEKETSSGEEQESEPKTESENQKESLSSEENSQSVEELKKKYSAVSLCNISTEVLKVINATEELIAESAGPWEFPPIPPDTEKGTFPLGTDQVRLDEQLTSLEENVYLAAGTVYGLEGQLSELEDAARCIHSGTDETELADLEDQVATAAAQVHHAEIQISDIESRISALTIAGLNIAPCGRLTRKRDQKQRNQVQTIDTSRQQRRKLPAPPVKAEKTEASSATTIKTFNRNFILQDSSTNRTKERKSTTKELMEPSLESAVMY", "length": 856, "header": "tr|A0A5G2RMW1-1|A0A5G2RMW1_PIG Isoform 1 of Myosin VIIA and Rab interacting protein OS=Sus scrofa OX=9823 GN=MYRIP PE=4 SV=1 CANONICAL=A0A5G2RMW1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQ36-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1/entry#A0A5G2QQ36-1", "sequence": { "sequence": "MRKAASVASSPSTRTLWSTAVCAAARPSPSSSTPSDAVGTVSSMSARAAAPTRSTRRCGSAACASRRGGSFFEATLENEGSISGSDSTFYRQSEGHSMMDTLAVALRVAEEAIEEAISKAEAYGDSLDKQNEASYLRDHKEELTEELATTILQKIIRKQKNKSEQRMEEEPEWPQPQSCSTKAADEGTTAFPGSHQASTTLWRSQSAFSLSREDALRTSSLEAASRQPKDQQPREEAALPNWKSVDRLDETSAAPVLQSPDGNWMALKDGALPPTRLLVKPKSGTFQALEAASSVASAYDEMGSDSEEDFDWREALSTLCPQPQGLPRHPQPQPMQVQGSDQGPSAASASSGLSPNPEAMCSDSETSSAGSSREAGHQARLSWLQRKAPRNPVAEKMRLQGELDVNFNPQAASRETSDSSEPEEAPHAADRRAKRWRRARGGSEEPSKELSSPNAHPPEGDTHQVSGDLSETDISSEARHRRSSTDTSEQKLRNRLYELAMKMSEKETSSGEEQESEPKTESENQKESLSSEENSQSVEELKKKYSAVSLCNISTEVLKVINATEELIAESAGPWEFPPIPPDTEKGTFPLGTDQVRLDEQLTSLEENVYLAAGTVYGLEGQLSELEDAARCIHSGTDETELADLEDQVATAAAQVHHAEIQISDIESRISALTIAGLNIAPCGRLTRKRDQKQRNQVQTIDTSRQQRRKLPAPPVKAEKTEASSATTIKTFNRNFILQDSSTNRTKERKSTTKELMEPSLESAVMY", "length": 767, "header": "tr|A0A5G2QQ36-1|A0A5G2RMW1_PIG Computationally mapped isoform of Myosin VIIA and Rab interacting protein OS=Sus scrofa OX=9823 GN=MYRIP PE=4 SV=1 CANONICAL=A0A5G2RMW1-1" }, "locus": { "chromosome": "13", "start_pos": 24554627, "end_pos": 24451808, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074801.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074801.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066835.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066835.1" } ] } }, { "isoform_ac": "A0A5G2R1V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1/entry#A0A5G2R1V5-1", "sequence": { "sequence": "MGRKLDLSGLTDDETEHVLQVVQRDFNLRKKEEERLSEMKQKLDEEGSKCSILSKHQNFVEHCCMRCCSPFTFLVNTKRRCGDCKFNVCKSCCSYQKHEKVWICCVCQQARVLRTQSLEWFYSNVKSRFKRFGSAKVLKNLYRKHRLESGVCFDILGGSFFEATLENEGSISGSDSTFYRQSEGHSMMDTLAVALRVAEEAIEEAISKAEAYGDSLDKQNEASYLRDHKEELTEELATTILQKIIRKQKNKSEQRMEEEPEWPQPQSCSTKAADEGTTAFPGSHQASTTLWRSQSAFSLSREDALRTSSLEAASRQPKDQQPREEAALPNWKSVDRLDETSAAPVLQSPDGNWMALKDGALPPTRLLVKPKSGTFQALEAASSVASAYDEMGSDSEEDFDWREALSTLCPQPQGLPRHPQPQPMQVQGSDQGPSAASASSGLSPNPEAMCSDSETSSAGSSREAGHQARLSWLQRKAPRNPVAEKMRLQGELDVNFNPQAASRETSDSSEPEEAPHAADRRAKRWRRARGGSEEPSKELSSPNAHPPEGDTHQVSGDLSETDISSEARHRRSSTDTSEQKLRNRLYELAMKMSEKETSSGEEQESEPKTESENQKESLSSEENSQSVEELKKVYLAAGTVYGLEGQLSELEDAARCIHSGTDETELADLEDQVATAAAQVHHAEIQISDIESRISALTIAGLNIAPCGRLTRKRDQKQRNQVQTIDTSRQQRRKLPAPPVKAEKTEASSATTIKTFNRNFILQDSSTNRTKERKSTTKELMEPSLESAVMY", "length": 791, "header": "tr|A0A5G2R1V5-1|A0A5G2RMW1_PIG Computationally mapped isoform of Myosin VIIA and Rab interacting protein OS=Sus scrofa OX=9823 GN=MYRIP PE=4 SV=1 CANONICAL=A0A5G2RMW1-1" }, "locus": { "chromosome": "13", "start_pos": 24554627, "end_pos": 24382668, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085155.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085155.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070330.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070330.1" } ] } }, { "isoform_ac": "A0A5G2RMW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1/entry#A0A5G2RMW1-1", "sequence": { "sequence": "MGRKLDLSGLTDDETEHVLQVVQRDFNLRKKEEERLSEMKQKLDEEGSKCSILSKHQNFVEHCCMRCCSPFTFLVNTKRRCGDCKFNVCKSCCSYQKHEKVWICCVCQQARVLRTQSLEWFYSNVKSRFKRFGSAKVLKNLYRKHRLESGVCFDILGGSFFEATLENEGSISGSDSTFYRQSEGHSMMDTLAVALRVAEEAIEEAISKAEAYGDSLDKQNEASYLRDHKEELTEELATTILQKIIRKQKNKSEQRMEEEPEWPQPQSCSTKAADEGTTAFPGSHQASTTLWRSQSAFSLSREDALRTSSLEAASRQPKDQQPREEAALPNWKSVDRLDETSAAPVLQSPDGNWMALKDGALPPTRLLVKPKSGTFQALEAASSVASAYDEMGSDSEEDFDWREALSTLCPQPQGLPRHPQPQPMQVQGSDQGPSAASASSGLSPNPEAMCSDSETSSAGSSREAGHQARLSWLQRKAPRNPVAEKMRLQGELDVNFNPQAASRETSDSSEPEEAPHAADRRAKRWRRARGGSEEPSKELSSPNAHPPEGDTHQVSGDLSETDISSEARHRRSSTDTSEQKLRNRLYELAMKMSEKETSSGEEQESEPKTESENQKESLSSEENSQSVEELKKKYSAVSLCNISTEVLKVINATEELIAESAGPWEFPPIPPDTEKGTFPLGTDQVRLDEQLTSLEENVYLAAGTVYGLEGQLSELEDAARCIHSGTDETELADLEDQVATAAAQVHHAEIQISDIESRISALTIAGLNIAPCGRLTRKRDQKQRNQVQTIDTSRQQRRKLPAPPVKAEKTEASSATTIKTFNRNFILQDSSTNRTKERKSTTKELMEPSLESAVMY", "length": 856, "header": "tr|A0A5G2RMW1-1|A0A5G2RMW1_PIG Isoform 1 of Myosin VIIA and Rab interacting protein OS=Sus scrofa OX=9823 GN=MYRIP PE=4 SV=1 CANONICAL=A0A5G2RMW1-1" }, "locus": { "chromosome": "13", "start_pos": 24554627, "end_pos": 24382668, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091236.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091236.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074015.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074015.1" } ] } }, { "isoform_ac": "F1SJQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1/entry#F1SJQ8-1", "sequence": { "sequence": "MGRKLDLSGLTDDETEHVLQVVQRDFNLRKKEEERLSEMKQKLDEEGSKCSILSKHQNFVEHCCMRCCSPFTFLVNTKRRCGDCKFNVCKSCCSYQKHEKVWICCVCQQARVLRTQSLEWFYSNVKSRFKRFGSAKVLKNLYRKHRLESGVCFDILGGSFFEATLENEGSISGSDSTFYRQSEGHSMMDTLAVALRVAEEAIEEAISKAEAYGDSLDKQNEASYLRDHKEELTEELATTILQKIIRKQKNKSEQRMEEEPEWPQPQSCSTKAADEGTTAFPGSHQASTTLWRSQSAFSLSREDALRTSSLEAASRQPKDQQPREEAALPNWKSVDRLDETSAAPVLQSPDGNWMALKDGALPPTRLLVKPKSGTFQALEAASSVASAYDEMGSDSEEDFDWREALSTLCPQPQGLPRHPQPQPMQVQGSDQGPSAASASSGLSPNPEAMCSDSETSSAGSSREAGHQARLSWLQRKAPRNPVAEKMRLQGELDVNFNPQAASRETSDSSEPEEAPHAADRRAKRWRRARGGSEEPSKELSSPNAHPPEGDTHQVSGDLSETDISSEARHRRSSTDTSEQKLRNRLYELAMKMSEKETSSGEEQESEPKTESENQKESLSSEENSQSKYSAVSLCNISTEVLKVINATEELIAESAGPWEFPPIPPDTEKGTFPLGTDQVRLDEQLTSLEENVYLAAGTVYGLEGQLSELEDAARCIHSGTDETELADLEDQVATAAAQVHHAEIQISDIESRISALTIAGLNIAPCGRLTRKRDQKQRNQVQTIDTSRQQRRKLPAPPVKAEKTEASSATTIKTFNRNFILQDSSTNRTKERKSTTKELMVSHLCLIVMVEM", "length": 852, "header": "tr|F1SJQ8-1|A0A5G2RMW1_PIG Computationally mapped isoform of Myosin VIIA and Rab interacting protein OS=Sus scrofa OX=9823 GN=MYRIP PE=4 SV=4 CANONICAL=A0A5G2RMW1-1" }, "locus": { "chromosome": "13", "start_pos": 24550452, "end_pos": 24382668, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012337.4", "url": "https://www.ensembl.org/id/ENSSSCT00000012337.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012015.4", "url": "https://www.ensembl.org/id/ENSSSCP00000012015.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQ36", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ36" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9824585", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9824585", "resource": "Reactome", "description": "Regulation of MITF-M-dependent genes involved in pigmentation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "pmid": "" }, { "name": "myosin binding", "id": "GO:0017022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017022", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "pmid": "" }, { "name": "protein kinase A binding", "id": "GO:0051018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051018", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMW1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 641, "end_pos": 643, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 835, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RMW1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 856, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RMW1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RMW1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMW1" }, { "id": "PS50916", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50916" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RabBD", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 124, "start_aa": "Lys", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 250, "end_pos": 252 }, { "start_pos": 641, "end_pos": 643 }, { "start_pos": 651, "end_pos": 653 }, { "start_pos": 833, "end_pos": 835 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1V0D2-1", "uniprot_ac": "A0A5K1V0D2", "uniprot_id": "A0A5K1V0D2_PIG", "mass": { "chemical_mass": 45616.0, "monoisotopic_mass": 45616.0 }, "refseq": {}, "gene_names": [ { "name": "MARCO", "type": "recommended", "evidence": [ { "id": "A0A5K1V0D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2" } ] } ], "protein_names": [ { "name": "Macrophage receptor with collagenous structure", "type": "synonym", "evidence": [ { "id": "A0A5K1V0D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V0D2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MARCO", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2", "locus": { "chromosome": "15", "start_pos": 24541283, "end_pos": 24503108, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015716", "url": "https://www.ensembl.org/id/ENSSSCG00000015716" } ] } } ], "crossref": [ { "id": "A0A5K1V0D2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1V0D2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015716", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015716", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19331:SF471", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19331:SF471", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QZ20", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZ20-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1V0D2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1V0D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFLALWQEGRSRGRCGGHGPLCLSPPGTSKGAPAHKEKVQKRAGVPCSPHSAAATFCPGCLSESKPKKRNGMNWFMFLVVIYLILLTVGTGMLVMTVLKLQEQLRALVIYPHNETLATEGSWSSFLQSIPPPAGDAPRLQILQTQLTQICARQEQLLRRVDNCTQIPGPPGPQGPPGIKGETGRKGDMGMKGDMGLMGPPGARGHKGDLGMPGSPGVAGVPGLKGDQGQPGTRGLPGLPGAAGSPGAKGEPGSPGLTGPTGPAGSPGSPGAEGLKGSKGDTGLQGQKGTKGESGFPGPAGLKGEKGSRGLEGSRGAPGLGGQKGEPGAKGSSGLQGAKGAKGEKGESMLSVRIIGSRNRGRAEIFYSGVWGTICDDDWDNSDATVFCRMLGYSSGSAVYNVGGGTGTIWLDNVACKGSEFTLWDCGKNAWGSHNCNHNEDAGVNCS", "length": 447, "header": "tr|A0A5K1V0D2-1|A0A5K1V0D2_PIG Isoform 1 of Macrophage receptor with collagenous structure OS=Sus scrofa OX=9823 GN=MARCO PE=1 SV=1 CANONICAL=A0A5K1V0D2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZ20-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2/entry#A0A5G2QZ20-1", "sequence": { "sequence": "MAFLALWQEGRSRGRCGGHGPLCLSPPGTSKGAPAHKEKVQKRAGVPCSPHSAAATFCPGCLSESKPKKRNGMNWFMFLVVIYLILLTVGTGMLVMTVLKLQEQLRALVIYPHNETLATEGSWSSFLQSIPPPAGDAPRLQILQTQLTQICARQEQLLRRVDNCTQIPGPPGPQGPPGIKGETGRKGDMGMKGDMGLMGPPGARGHKGDLGMPGSPGKSLCGIPWCQGSTPSSPDTLYGICCPGPAGSPGSPGAEGLKGSKGDTGNRGWGRGEDYFPAGPAGLKGEKGSRGLEGSRGAPGLGGQKGEPGAKGSSGLQGAKGAKGEKGESMLSVRIIGSRNRGRAEIFYSGVWGTICDDDWDNSDATVFCRMLGYSSGSAVYNVGGGTGTIWLDNVACKGSEFTLWDCGKNAWGSHNCNHNEDAGVNCS", "length": 428, "header": "tr|A0A5G2QZ20-1|A0A5K1V0D2_PIG Computationally mapped isoform of Macrophage receptor with collagenous structure OS=Sus scrofa OX=9823 GN=MARCO PE=1 SV=2 CANONICAL=A0A5K1V0D2-1" }, "locus": { "chromosome": "15", "start_pos": 24541141, "end_pos": 24518126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072928.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072928.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070128.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070128.2" } ] } }, { "isoform_ac": "A0A5K1V0D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2/entry#A0A5K1V0D2-1", "sequence": { "sequence": "MAFLALWQEGRSRGRCGGHGPLCLSPPGTSKGAPAHKEKVQKRAGVPCSPHSAAATFCPGCLSESKPKKRNGMNWFMFLVVIYLILLTVGTGMLVMTVLKLQEQLRALVIYPHNETLATEGSWSSFLQSIPPPAGDAPRLQILQTQLTQICARQEQLLRRVDNCTQIPGPPGPQGPPGIKGETGRKGDMGMKGDMGLMGPPGARGHKGDLGMPGSPGVAGVPGLKGDQGQPGTRGLPGLPGAAGSPGAKGEPGSPGLTGPTGPAGSPGSPGAEGLKGSKGDTGLQGQKGTKGESGFPGPAGLKGEKGSRGLEGSRGAPGLGGQKGEPGAKGSSGLQGAKGAKGEKGESMLSVRIIGSRNRGRAEIFYSGVWGTICDDDWDNSDATVFCRMLGYSSGSAVYNVGGGTGTIWLDNVACKGSEFTLWDCGKNAWGSHNCNHNEDAGVNCS", "length": 447, "header": "tr|A0A5K1V0D2-1|A0A5K1V0D2_PIG Isoform 1 of Macrophage receptor with collagenous structure OS=Sus scrofa OX=9823 GN=MARCO PE=1 SV=1 CANONICAL=A0A5K1V0D2-1" }, "locus": { "chromosome": "15", "start_pos": 24541141, "end_pos": 24518126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000034415.4", "url": "https://www.ensembl.org/id/ENSSSCT00000034415.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030143.3", "url": "https://www.ensembl.org/id/ENSSSCP00000030143.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 261, "start_aa": "Thr", "end_pos": 261, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr261", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZ20", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZ20" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V0D2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V0D2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "scavenger receptor activity", "id": "GO:0005044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005044", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V0D2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2" } ], "pmid": "" }, { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V0D2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1V0D2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 447, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1V0D2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1V0D2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1V0D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V0D2" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 352, "end_pos": 447, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 261 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 445, "end_pos": 447 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RN94-1", "uniprot_ac": "A0A5G2RN94", "uniprot_id": "A0A5G2RN94_PIG", "mass": { "chemical_mass": 60527.0, "monoisotopic_mass": 60527.0 }, "refseq": {}, "gene_names": [ { "name": "SLC5A10", "type": "recommended", "evidence": [ { "id": "A0A5G2RN94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94" } ] } ], "protein_names": [ { "name": "Sodium/mannose cotransporter SLC5A10", "type": "recommended", "evidence": [ { "id": "A0A5G2RN94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94/entry#names_and_taxonomy" } ] }, { "name": "Sodium/glucose cotransporter 5", "type": "synonym", "evidence": [ { "id": "A0A5G2RN94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 5 member 10", "type": "synonym", "evidence": [ { "id": "A0A5G2RN94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Electrogenic Na+-coupled sugar symporter that actively transports D-mannose or D-fructose at the plasma membrane, with a Na+ to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na+ electrochemical gradient set by the Na+/K+ pump. Exclusively recognizes sugar substrates having a pyranose ring with an axial hydroxyl group on carbon 2. Has likely evolved to enable renal reabsorption of D-mannose, an important constituent of oligosaccharide chains of glycoproteins. Contributes to dietary D-fructose reabsorption from glomerular filtrate across the brush border of the kidney.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R9#function" }, { "database": "UniProtKB", "id": "ARBA00045692", "url": "https://www.uniprot.org/uniprotkb/ARBA00045692#function" }, { "database": "UniProtKB", "id": "A0A5G2RN94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94#function" }, { "database": "UniProtKB", "id": "F1SB19", "url": "https://www.uniprot.org/uniprotkb/F1SB19#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC5A10", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94", "locus": { "chromosome": "12", "start_pos": 60281885, "end_pos": 60332141, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000053434", "url": "https://www.ensembl.org/id/ENSSSCG00000053434" } ] } } ], "crossref": [ { "id": "A0A5G2RN94", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RN94", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000018049", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000018049", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11819", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11819", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11819:SF128", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11819:SF128", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-189200", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-189200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "72907", "url": "https://www.rhea-db.org/rhea/72907", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72915", "url": "https://www.rhea-db.org/rhea/72915", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R1R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RN94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RN94-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SB19", "url": "https://www.uniprot.org/uniprotkb/F1SB19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SB19-1", "url": "https://www.uniprot.org/uniprotkb/F1SB19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ADNSSSDPHAPGPQLSVADVVIVAVYFAVNMAVGVWSSCRASRNTVSGYFLAGRDMMWWPIGASLFASSEGSGLFVGLAGSGAAGGLAVAGFEWHATYVLLALAWVFVPIYISSEIVTMPEYIQKRYGGQRIRMYLSVLSLLLSIFTKISIDLYAGALFVHICLGWNFYLSTCLMLVITALYTIAGGLAAVIYTDALQTLIMVVGAVILTVKAFQQIGGYEQLAAAYAQAIPSKTISNTTCHLPRADAMHMFRDPATGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKGGSILASYLKMLPMGLMVMPGMISRVLFPGLRGLMVAVMMAALMSSLTSIFNSSSTLFTMDVWRRLRPRAGERELLLVGRLVIVVLIGVSVAWIPVLQGSNSGQLFIYMQSVTSSLAPPVTAVFVLGIFWRRANEQGAFWGLMVGLAVGAWRLVLEFLHPAPPCGHPDVRPALLRTVHYLHFAVALFVLSGAVVAAVSLLTPPPAGVQIENLTWWTLARDRPSGAKTGDSPASQKHAFWARVCSLNAVLLVCVNLFFYAYFA", "length": 559, "header": "tr|A0A5G2RN94-1|A0A5G2RN94_PIG Isoform 1 of Sodium/mannose cotransporter SLC5A10 OS=Sus scrofa OX=9823 GN=SLC5A10 PE=3 SV=2 CANONICAL=A0A5G2RN94-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94/entry#A0A5G2R1R9-1", "sequence": { "sequence": "ADNSSSDPHAPGPQLSVADVVIVAVYFAVNMAVGVWSSCRASRNTVSGYFLAGRDMMWWPIGASLFASSEGSGLFVGLAGSGAAGGLAVAGFEWHATYVLLALAWVFVPIYISSEIVTMPEYIQKRYGGQRIRMYLSVLSLLLSIFTKISIDLYAGALFVHICLGWNFYLSTCLMLVITALYTIAAFQQIGGYEQLAAAYAQAIPSKTISNTTCHLPRADAMHMFRDPATGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKGGSILASYLKMLPMGLMVMPGMISRVLFPDDVGCVVPSECLRACGAEIGCSNIAYPKLVMELMPTGLRGLMVAVMMAALMSSLTSIFNSSSTLFTMDVWRRLRPRAGERELLLVGRLVIVVLIGVSVAWIPVLQGSNSGQLFIYMQSVTSSLAPPVTAVFVLGIFWRRANEQGAFWGLMVGLAVGAWRLVLEFLHPAPPCGHPDVRPALLRTVHYLHFAVALFVLSGAVVAAVSLLTPPPAGVQIENLTWWTLARDRPSGAKTGDSPASQKHAFWARVCSLNAVLLVCVNLFFYAYFA", "length": 568, "header": "tr|A0A5G2R1R9-1|A0A5G2RN94_PIG Computationally mapped isoform of Sodium/mannose cotransporter SLC5A10 OS=Sus scrofa OX=9823 GN=SLC5A10 PE=3 SV=2 CANONICAL=A0A5G2RN94-1" }, "locus": { "chromosome": "12", "start_pos": 60332130, "end_pos": 60282085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068171.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068171.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068137.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068137.2" } ] } }, { "isoform_ac": "A0A5G2RN94-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94/entry#A0A5G2RN94-1", "sequence": { "sequence": "ADNSSSDPHAPGPQLSVADVVIVAVYFAVNMAVGVWSSCRASRNTVSGYFLAGRDMMWWPIGASLFASSEGSGLFVGLAGSGAAGGLAVAGFEWHATYVLLALAWVFVPIYISSEIVTMPEYIQKRYGGQRIRMYLSVLSLLLSIFTKISIDLYAGALFVHICLGWNFYLSTCLMLVITALYTIAGGLAAVIYTDALQTLIMVVGAVILTVKAFQQIGGYEQLAAAYAQAIPSKTISNTTCHLPRADAMHMFRDPATGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKGGSILASYLKMLPMGLMVMPGMISRVLFPGLRGLMVAVMMAALMSSLTSIFNSSSTLFTMDVWRRLRPRAGERELLLVGRLVIVVLIGVSVAWIPVLQGSNSGQLFIYMQSVTSSLAPPVTAVFVLGIFWRRANEQGAFWGLMVGLAVGAWRLVLEFLHPAPPCGHPDVRPALLRTVHYLHFAVALFVLSGAVVAAVSLLTPPPAGVQIENLTWWTLARDRPSGAKTGDSPASQKHAFWARVCSLNAVLLVCVNLFFYAYFA", "length": 559, "header": "tr|A0A5G2RN94-1|A0A5G2RN94_PIG Isoform 1 of Sodium/mannose cotransporter SLC5A10 OS=Sus scrofa OX=9823 GN=SLC5A10 PE=3 SV=2 CANONICAL=A0A5G2RN94-1" }, "locus": { "chromosome": "12", "start_pos": 60332130, "end_pos": 60282085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068252.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068252.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074260.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074260.2" } ] } }, { "isoform_ac": "F1SB19-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94/entry#F1SB19-1", "sequence": { "sequence": "MAADNSSSDPHAPGPQLSVADVVIVAVYFAVNMAVGVWSSCRASRNTVSGYFLAGRDMMWCRHLRPCASLFASSEGSGLFVGLAGSGAAGGLAVAGFEWHATYVLLALAWVFVPIYISSEIVTMPEYIQKRYGGQRIRMYLSVLSLLLSIFTKISIDLYAGALFVHICLGWNFYLSTCLMLVITALYTIAGGLAAVIYTDALQTLIMVVGAVILTVKAFQQIGGYEQLAAAYAQAIPSKTISNTTCHLPRADAMHMFRDPATGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKGGSILASYLKMLPMGLMVMPGMISRVLFPDDVGCVVPSECLRACGAEIGCSNIAYPKLVMELMPTGLRGLMVAVMMAALMSSLTSIFNSSSTLFTMDVWRRLRPRAGERELLLVGRLVIVVLIGVSVAWIPVLQGSNSGQLFIYMQSVTSSLAPPVTAVFVLGIFWRRANEQGAFWGLMVGLAVGAWRLVLEFLHPAPPCGHPDVRPALLRTVHYLHFAVALFVLSGAVVAAVSLLTPPPAGVQIENLTWWTLARDRPSGAKTGDSPASQKHAFWARVCSLNAVLLVCVNLFFYAYFA", "length": 600, "header": "tr|F1SB19-1|F1SB19_PIG Computationally mapped isoform of Sodium/mannose cotransporter SLC5A10 OS=Sus scrofa OX=9823 GN=SLC5A10 PE=3 SV=3 CANONICAL=A0A5G2RN94-1" }, "locus": { "chromosome": "12", "start_pos": 60332136, "end_pos": 60282085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019643.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019643.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019123.4", "url": "https://www.ensembl.org/id/ENSSSCP00000019123.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1R9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1R9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-189200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-189200", "resource": "Reactome", "description": "Cellular hexose transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94" } ], "pmid": "" }, { "name": "mannose:sodium symporter activity", "id": "GO:0140929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140929", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94" } ], "pmid": "" }, { "name": "fructose:sodium symporter activity", "id": "GO:0140930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN94", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN94" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "72907", "name": "", "equation": "D-mannose(out) + Na(+)(out) = D-mannose(in) + Na(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72907", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72907" } ] }, { "id": "72915", "name": "", "equation": "D-fructopyranose(out) + Na(+)(out) = D-fructopyranose(in) + Na(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72915", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72915" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RN94-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 559, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RN94-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RN94" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 238, "end_pos": 240 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 508, "end_pos": 510 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RH45-1", "uniprot_ac": "A0A5G2RH45", "uniprot_id": "A0A5G2RH45_PIG", "mass": { "chemical_mass": 19860.0, "monoisotopic_mass": 19860.0 }, "refseq": {}, "gene_names": [ { "name": "KLRD1", "type": "recommended", "evidence": [ { "id": "A0A5G2RH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ] } ], "protein_names": [ { "name": "Natural killer cells antigen CD94", "type": "recommended", "evidence": [ { "id": "A0A5G2RH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45/entry#names_and_taxonomy" } ] }, { "name": "Killer cell lectin-like receptor subfamily D member 1", "type": "synonym", "evidence": [ { "id": "A0A5G2RH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KLRD1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45", "locus": { "chromosome": "5", "start_pos": 61666654, "end_pos": 61673129, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000642", "url": "https://www.ensembl.org/id/ENSSSCG00000000642" } ] } } ], "crossref": [ { "id": "A0A5G2RH45", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RH45", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000642", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000642", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22800", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22800", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22800:SF252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22800:SF252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2424491", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2424491", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R204", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R204", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R204-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R204-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RH45-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAFQTTAWRLISGVLGVICLLLMAALGILLKNSFNKQNVQPTLSPGPSTDPLEGSDCCSCQEKWIGYQCNCYFISNESKTWKDSRNFCISHNSSLLQVQNRNELDFMNSSAHFYWIGLSFSEEHNAWLWEDNSTLSQDLFLVNTENCVIYSPSRNSLDEDCGSRHLFICKQHLS", "length": 175, "header": "tr|A0A5G2RH45-1|A0A5G2RH45_PIG Isoform 1 of Natural killer cells antigen CD94 OS=Sus scrofa OX=9823 GN=KLRD1 PE=4 SV=1 CANONICAL=A0A5G2RH45-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R204-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45/entry#A0A5G2R204-1", "sequence": { "sequence": "MAAFNKQNVQPTLSPGPSTDPLEGSDCCSCQEKWIGYQCNCYFISNESKTWKDSRNFCISHNSSLLQVQNRNELDFMNSSAHFYWIGLSFSEEHNAWLWEDNSTLSQDLFLVNTENCVIYSPSRNSLDEDCGSRHLFICKQHLS", "length": 144, "header": "tr|A0A5G2R204-1|A0A5G2RH45_PIG Computationally mapped isoform of Natural killer cells antigen CD94 OS=Sus scrofa OX=9823 GN=KLRD1 PE=4 SV=1 CANONICAL=A0A5G2RH45-1" }, "locus": { "chromosome": "5", "start_pos": 61671933, "end_pos": 61666657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077438.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077438.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070380.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070380.1" } ] } }, { "isoform_ac": "A0A5G2RH45-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45/entry#A0A5G2RH45-1", "sequence": { "sequence": "MAAFQTTAWRLISGVLGVICLLLMAALGILLKNSFNKQNVQPTLSPGPSTDPLEGSDCCSCQEKWIGYQCNCYFISNESKTWKDSRNFCISHNSSLLQVQNRNELDFMNSSAHFYWIGLSFSEEHNAWLWEDNSTLSQDLFLVNTENCVIYSPSRNSLDEDCGSRHLFICKQHLS", "length": 175, "header": "tr|A0A5G2RH45-1|A0A5G2RH45_PIG Isoform 1 of Natural killer cells antigen CD94 OS=Sus scrofa OX=9823 GN=KLRD1 PE=4 SV=1 CANONICAL=A0A5G2RH45-1" }, "locus": { "chromosome": "5", "start_pos": 61671933, "end_pos": 61666657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082267.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082267.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074449.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074449.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R204", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R204" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2424491", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2424491", "resource": "Reactome", "description": "DAP12 signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "MHC class I protein complex binding", "id": "GO:0023024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023024", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "protein antigen binding", "id": "GO:1990405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990405", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "HLA-A specific activating MHC class I receptor activity", "id": "GO:0030108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030108", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "MHC class Ib protein binding, via antigen binding groove", "id": "GO:0023030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023030", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "HLA-E specific inhibitory MHC class Ib receptor activity", "id": "GO:0062082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062082", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "natural killer cell mediated immunity", "id": "GO:0002228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002228", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "negative regulation of natural killer cell mediated cytotoxicity", "id": "GO:0045953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045953", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell mediated cytotoxicity", "id": "GO:0045954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045954", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "negative regulation of T cell mediated cytotoxicity", "id": "GO:0001915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001915", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" }, { "name": "stimulatory C-type lectin receptor signaling pathway", "id": "GO:0002223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002223", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RH45", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RH45-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 175, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RH45-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RH45" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RH45" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 171, "start_aa": "Tyr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 133, "end_pos": 135 }, { "start_pos": 77, "end_pos": 79 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RHF4-1", "uniprot_ac": "A0A5G2RHF4", "uniprot_id": "A0A5G2RHF4_PIG", "mass": { "chemical_mass": 145009.0, "monoisotopic_mass": 145009.0 }, "refseq": {}, "gene_names": [ { "name": "CNTNAP5", "type": "recommended", "evidence": [ { "id": "A0A5G2RHF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4" } ] } ], "protein_names": [ { "name": "Contactin associated protein family member 5", "type": "synonym", "evidence": [ { "id": "A0A5G2RHF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F9H5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9H5#function" }, { "database": "UniProtKB", "id": "ARBA00003165", "url": "https://www.uniprot.org/uniprotkb/ARBA00003165#function" }, { "database": "UniProtKB", "id": "F1RXZ0", "url": "https://www.uniprot.org/uniprotkb/F1RXZ0#function" }, { "database": "UniProtKB", "id": "A0A5G2R5U4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5U4#function" }, { "database": "UniProtKB", "id": "A0A5G2RHF4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHF4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CNTNAP5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4", "locus": { "chromosome": "15", "start_pos": 26881597, "end_pos": 27740038, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015726", "url": "https://www.ensembl.org/id/ENSSSCG00000015726" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015726", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015726", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00057", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00057", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GWNCGRE", "url": "https://omabrowser.org/oma/group/GWNCGRE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R5U4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5U4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RHF4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RHF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9H5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9H5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXZ0", "url": "https://www.uniprot.org/uniprotkb/F1RXZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXZ0-1", "url": "https://www.uniprot.org/uniprotkb/F1RXZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSGPRLTSVFTLLFSGLWHLGLTAANYNCDDPLASLLSPMAFSSSSDLTGAHSPAQLNRRAGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRHGSSDWVTSYSLMFSDTGRNWKQYKQEDSIWTFAGNMNADSVMHHKLLHSVRARFIRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDQITLELQKGRLALHLNLDDSKPRLSSSPPSATLGSLLDDQHWHSVLLERVGKQVNFTVDKHTQHFRTKGEADALDIDYELSFGGIPVPGKPGTFLKKNFHGCMENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSSSYLLLPGTPQLDGLSVSFQFRTWNQDGLLLSTMLSEGSGTLLLSLEGGRLRLVIQKMTERAAEILTGRNLNDGLWHLLSINARRNRITLTLDNDAASPAQDTSRMQIYSGNSYYFGGCPDNLTDSQCLNPTKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCTDTGYVGATCHNSLYEQSCEVYRHQGNTAGFFYIDSDGSGPLAPFQVYCNITEDKIWTSVQHNHMELTHVRGASAEKPYSMVLDYKGSLEQLTAVIDGSEHCEQEVAYHCKRSRLLNTPDGAPLTWWMGRSNERHPYWGGAPPGVQQCDCGLDESCLDIRHFCNCDADQEEWTNDTGFLSFKDHLPVTQIVITDTNRSNSEAAWRIGPLRCYGDRHFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPIELIVQSPALLNDNQWHYVRAERNLKETSLQVDSLPRVTKKTSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKLDLEERAKTSGVRPGCPGHCSSYGSTCHNGGKCVEKHSGYFCDCTTSPYEGPFCKKEVSAVFEAGTSVTYVFQEPYPVTKNLSLSSSAIYVDAAPSRENIALSFVTAQVPGLLLYVNSSSQDSLAVLICKNGSLQVRYQLSKEEIHVFTIDTENFANRRLHHLKINREGRGLTIQVDEQLRLSYNFSPEAEFRAGKSLTLGKVTETLGLDAEVAKANILGFIGCLASVQYNHIAPLKAALRHATIAPVTIQGTLTESSCSSVMDSDVNAVTTVHSSSDLFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIISVIGIMTRFLYQHRQSHRTNQMEKEYPENLDTSFRNDIDLQSTVSECKREYFI", "length": 1304, "header": "tr|A0A5G2RHF4-1|A0A5G2RHF4_PIG Isoform 1 of Contactin associated protein family member 5 OS=Sus scrofa OX=9823 GN=CNTNAP5 PE=1 SV=1 CANONICAL=A0A5G2RHF4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R5U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4/entry#A0A5G2R5U4-1", "sequence": { "sequence": "TGTSTEISQIINPLYHSGNSEFFYHCTISITVERCDWIPMDVPGALAGKATALVAQTSSGLPFSLQTFAGNMNADSVMHHKLLHSVRARFIRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDQITLELQKGRLALHLNLDDSKPRLSSSPPSATLGSLLDDQHWHSVLLERVGKQVNFTVDKHTQHFRTKGEADALDIDYELSFGGIPVPGKPGTFLKKNFHGCMENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSSSYLLLPGTPQLDGLSVSFQFRTWNQDGLLLSTMLSEGSGTLLLSLEGGRLRLVIQKMTERAAEILTGRNLNDGLWHLLSINARRNRITLTLDNDAASPAQDTSRMQIYSGNSYYFGGCPDNLTDSQCLNPTKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCTDTGYVGATCHNSLYEQSCEVYRHQGNTAGFFYIDSDGSGPLAPFQVYCNITEDKIWTSVQHNHMELTHVRGASAEKPYSMVLDYKGSLEQLTAVIDGSEHCEQEVAYHCKRSRLLNTPDGAPLTWWMGRSNERHPYWGGAPPGVQQCDCGLDESCLDIRHFCNCDADQEEWTNDTGFLSFKDHLPVTQIVITDTNRSNSEAAWRIGPLRCYGDRHFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPIELIVQSPALLNDNQWHYVRAERNLKETSLQVDSLPRVTKKTSEEGHFRLQLNSQLMISATSKMTVEAYSIIHVKTLNLGLSMEYFHACFSLSYFAEVSAVFEAGTSVTYVFQEPYPVTKNLSLSSSAIYVDAAPSRENIALSFVTAQVPGLLLYVNSSSQDSLAVLICKNGSLQVRYQLSKEEIHVFTIDTENFANRRLHHLKINREGRGLTIQVDEQLRLSYNFSPEAEFRAGKSLTLGKVTETLGLDAEVAKANILGFIGCLASVQYNHIAPLKAALRHATIAPVTIQGTLTESSCSSVMDSDVNAVTTVHSSSDLFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIISVIGIMTRFLYQHRQSHRTNQMEKEYPENLDTSFRNDIDLQSTVSECKREYFI", "length": 1202, "header": "tr|A0A5G2R5U4-1|A0A5G2RHF4_PIG Computationally mapped isoform of Contactin associated protein family member 5 OS=Sus scrofa OX=9823 GN=CNTNAP5 PE=1 SV=1 CANONICAL=A0A5G2RHF4-1" }, "locus": { "chromosome": "15", "start_pos": 27362814, "end_pos": 26882565, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074462.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074462.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065960.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065960.1" } ] } }, { "isoform_ac": "A0A5G2RHF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4/entry#A0A5G2RHF4-1", "sequence": { "sequence": "MDSGPRLTSVFTLLFSGLWHLGLTAANYNCDDPLASLLSPMAFSSSSDLTGAHSPAQLNRRAGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRHGSSDWVTSYSLMFSDTGRNWKQYKQEDSIWTFAGNMNADSVMHHKLLHSVRARFIRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDQITLELQKGRLALHLNLDDSKPRLSSSPPSATLGSLLDDQHWHSVLLERVGKQVNFTVDKHTQHFRTKGEADALDIDYELSFGGIPVPGKPGTFLKKNFHGCMENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSSSYLLLPGTPQLDGLSVSFQFRTWNQDGLLLSTMLSEGSGTLLLSLEGGRLRLVIQKMTERAAEILTGRNLNDGLWHLLSINARRNRITLTLDNDAASPAQDTSRMQIYSGNSYYFGGCPDNLTDSQCLNPTKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCTDTGYVGATCHNSLYEQSCEVYRHQGNTAGFFYIDSDGSGPLAPFQVYCNITEDKIWTSVQHNHMELTHVRGASAEKPYSMVLDYKGSLEQLTAVIDGSEHCEQEVAYHCKRSRLLNTPDGAPLTWWMGRSNERHPYWGGAPPGVQQCDCGLDESCLDIRHFCNCDADQEEWTNDTGFLSFKDHLPVTQIVITDTNRSNSEAAWRIGPLRCYGDRHFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPIELIVQSPALLNDNQWHYVRAERNLKETSLQVDSLPRVTKKTSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKLDLEERAKTSGVRPGCPGHCSSYGSTCHNGGKCVEKHSGYFCDCTTSPYEGPFCKKEVSAVFEAGTSVTYVFQEPYPVTKNLSLSSSAIYVDAAPSRENIALSFVTAQVPGLLLYVNSSSQDSLAVLICKNGSLQVRYQLSKEEIHVFTIDTENFANRRLHHLKINREGRGLTIQVDEQLRLSYNFSPEAEFRAGKSLTLGKVTETLGLDAEVAKANILGFIGCLASVQYNHIAPLKAALRHATIAPVTIQGTLTESSCSSVMDSDVNAVTTVHSSSDLFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIISVIGIMTRFLYQHRQSHRTNQMEKEYPENLDTSFRNDIDLQSTVSECKREYFI", "length": 1304, "header": "tr|A0A5G2RHF4-1|A0A5G2RHF4_PIG Isoform 1 of Contactin associated protein family member 5 OS=Sus scrofa OX=9823 GN=CNTNAP5 PE=1 SV=1 CANONICAL=A0A5G2RHF4-1" }, "locus": { "chromosome": "15", "start_pos": 27739942, "end_pos": 26882565, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086471.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086471.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070771.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070771.1" } ] } }, { "isoform_ac": "A0A8W4F9H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4/entry#A0A8W4F9H5-1", "sequence": { "sequence": "MDSGPRLTSVFTLLFSGLWHLGLTAANYNCDDPLASLLSPMAFSSSSDLTGAHSPAQLNRRAGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRHGSSDWVTSYSLMFSDTGRNWKQYKQEDSIWTFAGNMNADSVMHHKLLHSVRARFIRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDQITLELQKGRLALHLNLDDSKPRLSSSPPSATLGSLLDDQHWHSVLLERVGKQVNFTVDKHTQHFRTKGEADALDIDYELSFGGIPVPGKPGTFLKKNFHGCMENLYYNGVNIIDLAKRRKHQIYTVGNVTFSCSEPQIVPITFVNSSSSYLLLPGTPQLDGLSVSFQFRTWNQDGLLLSTMLSEGSGTLLLSLEGGRLRLVIQKMTERAAEILTGRNLNDGLWHLLSINARRNRITLTLDNDAASPAQDTSRMQIYSGNSYYFGGCPDNLTDSQCLNPTKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCTDTGYVGATCHNDKIWTSVQHNHMELTHVRGASAEKPYSMVLDYKGSLEQLTAVIDGSEHCEQEVAYHCKRSRLLNTPDGAPLTWWMGRSNERHPYWGGAPPGVQQCDCGLDESCLDIRHFCNCDADQEEWTNDTGFLSFKDHLPVTQIVITDTNRSNSEAAWRIGPLRCYGDRHFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPIELIVQSPALLNDNQWHYVRAERNLKETSLQVDSLPRVTKKTSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKLDLEERAKTSGVRPGCPGHCSSYGSTCHNGGKCVEKHSGYFCDCTTSPYEGPFCKKEVSAVFEAGTSVTYVFQEPYPVTKNLSLSSSAIYVDAAPSRENIALSFVTAQVPGLLLYVNSSSQDSLAVLICKNGSLQVRYQLSKEEIHVFTIDTENFANRRLHHLKINREGRGLTIQVDEQLRLSYNFSPEAEFRAGKSLTLGKVTETLGLDAEVAKANILGFIGCLASVQYNHIAPLKAALRHATIAPVTIQGTLTESSCSSVMDSDVNAVTTVHSSSDLFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIISVIGIMTRFLYQHRQSHRTNQMEKEYPENLDTSFRNDIDLQSTVSECKREYFI", "length": 1264, "header": "tr|A0A8W4F9H5-1|A0A5G2RHF4_PIG Computationally mapped isoform of Contactin associated protein family member 5 OS=Sus scrofa OX=9823 GN=CNTNAP5 PE=1 SV=1 CANONICAL=A0A5G2RHF4-1" }, "locus": { "chromosome": "15", "start_pos": 27739942, "end_pos": 26882565, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092269.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092269.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075481.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075481.1" } ] } }, { "isoform_ac": "F1RXZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4/entry#F1RXZ0-1", "sequence": { "sequence": "TGTSTEISQIINPLYHSGNSEFFYHCTISITVERCDWIPMDVPGALAGKATALVAQTSSGLPFSLQTFAGNMNADSVMHHKLLHSVRARFIRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDQITLELQKGRLALHLNLDDSKPRLSSSPPSATLGSLLDDQHWHSVLLERVGKQVNFTVDKHTQHFRTKGEADALDIDYELSFGGIPVPGKPGTFLKKNFHGCMENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSSSYLLLPGTPQLDGLSVSFQFRTWNQDGLLLSTMLSEGSGTLLLSLEGGRLRLVIQKMTERAAEILTGRNLNDGLWHLLSINARRNRITLTLDNDAASPAQDTSRMQIYSGNSYYFGGCPDNLTDSQCLNPTKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCTDTGYVGATCHNSLYEQSCEVYRHQGNTAGFFYIDSDGSGPLAPFQVYCNITEDKIWTSVQHNHMELTHVRGASAEKPYSMVLDYKGSLEQLTAVIDGSEHCEQEVAYHCKRSRLLNTPDGAPLTWWMGRSNERHPYWGGAPPGVQQCDCGLDESCLDIRHFCNCDADQEEWTNDTGFLSFKDHLPVTQIVITDTNRSNSEAAWRIGPLRCYGDRHFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPIELIVQSPALLNDNQWHYVRAERNLKETSLQVDSLPRVTKKTSEEGHFRLQLNSQLFVGGTSSRQKETGSGGEGKVTSGVRPGCPGHCSSYGSTCHNGGKCVEKHSGYFCDCTTSPYEGPFCKKEVSAVFEAGTSVTYVFQEPYPVTKNLSLSSSAIYVDAAPSRENIALSFVTAQVPGLLLYVNSSSQDSLAVLICKNGSLQVRYQLSKEEIHVFTIDTENFANRRLHHLKINREGRGLTIQVDEQLRLSYNFSPEAEFRAGKSLTLGKVTETLGLDAEVAKANILGFIGCLASVQYNHIAPLKAALRHATIAPVTIQGTLTESSCSSVMDSDVNAVTTVHSSSDLFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIISVIGIMTRFLYQHRQSHRTNQMEKEYPENLDTSFRNDIDLQSTVSECKREYFI", "length": 1230, "header": "tr|F1RXZ0-1|A0A5G2RHF4_PIG Computationally mapped isoform of Contactin associated protein family member 5 OS=Sus scrofa OX=9823 GN=CNTNAP5 PE=1 SV=3 CANONICAL=A0A5G2RHF4-1" }, "locus": { "chromosome": "15", "start_pos": 27362814, "end_pos": 26882565, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017126.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017126.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016666.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016666.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F9H5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9H5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q0V8T6-1", "protein_name": "Contactin-associated protein like 5-1", "gene_name": "Cntnap5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSLQRLNGLLTLVLSALWHLGLTASNYNCDDPLASFFSPMTFSSSLDLTGSYSSAQLNWKMGTGGWSPVDSNAQQWLQIDLGNRVEITAVATQGRYGSSDWVTSYRLMFSDTGHNWQHYTQEDSIWTFVGNMNADSVVHHRLLHSMRARFVRFVPLEWNPNGKIGMRVEAYGCSYRSDVADFDGRSTLLYRFNQKTMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHVTLELQKGRLALYLNLDDSKARLSSTVPLVIMGSLLDDQHWHSVLLERVGKQANFTVDMNTQHFQTKGETDALDIDYELSFGGIPVPSKPGTFVKKNFHGCMENLYYNGVNIIDLAKRRKHQIYSGNVTFSCSEPQIVPITFVNSRSSYLMLPGTPQIDGLSVSFQFRTWNEDGLLLSTELSEGSGTLLLILEGGTLRLLIKKVAGHGTEIKTGSGLNDGLWHSVSINARRNRVTLTLDNDAASPAPETSRKQIYSGKSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGHCAQTWTTFYCNCSDTGYTGATCHDSIYEQSCEVYRHKGHTAGFFYVDSDGSGPLGPLQVYCNITEDKIWMTVQHNNTELTRVQGSSPEKPYSMTLNYGGSMEQLEALIDGSEYCEQELKYHCRRSRLLNTLDGTPFTWWIGRSNERHPYWEGSVPGVQQCGCGLEESCLDNAYFCNCDADMDEWSNNTGLFSLKDHLPVTHVIITDTNRSNSEAAWRIGPLRCNGDRHFWNAVSFSTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFLRLEMSSPSEVTFTIDVGNGPVELLVQSPYPLNDNQWHYIRAERNVKETSLQVDNLPLSLREASEEAYFRLHLTSQLFVGGTSSRQKGFLGCMRSLHLNGQNTDLIERAKLMSGVTPGCPGHCSSYSSNCHNGGKCVEKQSGYSCDCTNSPNEGPFCQKEISALFDPGTSVTYMFQEPYLVIKNTSLLSSPIYTDTARSKETIMLNFLTAQAPTILLYLNFSSQKFLAILLSSNGSLQIRFRLSKGESHVYTMSTENLANGRVHQVKISKDGPEISIQMDQQLFSYNFSTKVEFWTLKSLVLGKVTETLGLDPEVAKVNILGFLGCLSSVQYNHIAPLKAALRHAGVAPVTVHGTLTESGCDSTLDSDVNAVTTVHSSLEPIGKRDEQEPLTNTVQSDSAVIGGIIAVVTFVTFCVIGIMICFLYQHKQSHRTNQTKEKEYPETLSNSFRNVIDLQNTASECKREYFI", "length": 1305 }, "evidence": [ { "id": "A0A5G2RHF4", "url": "https://omabrowser.org/oma/group/A0A5G2RHF4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0V8T9-1", "protein_name": "Contactin-associated protein like 5-1", "gene_name": "Cntnap5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSVPRLNSVLTLVLSGLWHLGLTATNYNCDDPLSNFLSLKAFSSSSDITGSSSSAQLNWRMGTGGWSPADSNAQQWLQIDLQNRVEITAVATQGRYGSSDWVTSYRLMFSDTGHNWQPYNQEDSIWTFVGNMNSDSVVHHKLLHSVRARFVRFVPLEWNPNGKIGMRVEAYGCSYRSDVADFDGRSSLLYRFNQKTMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALYLNLDDSKARLSSTVPLVILGSLLDDQHWHSVLLERVGKQANFTVDMNTQHFRTKGDTDSLDIDYELSFGGIPVPSKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYSGNVTFSCSEPQIVPITFINSRSSYLMLPGTPQIDGLSVSFQFRTWNEDGLLLSTELSEGSGTLLLILEGGTLRLLIKKVARHGTEILTGSGLNDGLWHSVSINARRNRVTLTLDNDAASPAPDTSRIQIYSGKSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGSFSDLHIDLCSIKDRCLPNYCEHGGHCDQTWTTFYCNCSGTGYTGATCHDSIYEQSCEVYRHRGHTAGFFYVDSDGSGPLGPLQVYCNITEDKIWMTVQHNNTELTRVQGSSPENPYSMTLNYGGSMEQLEALIDGSEYCEQEVIYHCRRSRLLNTPDGAPFTWWIGRSTERHPYWGGAVPGVQQCGCGLEESCLDSRHFCNCDADIDEWANDTGLFSFKDHLPVTQIIIMDTNRTNSEAAWRIGPLRCYGDRHFWNAVSFSTEASYLHFPTFHTEFSADISFFFKTTALSGVFLENLGIKDFFRLEMSSPSEVTFAIDVGNGPIELLVQSPYPLNDNQWHYIRAETNLKETSLQVDNLPQSMREASEGGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLLLNGHKVDLEERAKVTSGVRPGCPGHCSSYGSNCHNGGKCVEKHTGYSCDCTNSPYEGPFCRKEISALFDSGTSVTYMFQEPYPVTKNTSLSSSAIYTDLAPFKETIMLSFMTTQAPTLLLYLNFSSQNFLAILLSRNGSLQVRYRLSKDESHVFNMDTENLANRRVHQVKISRDGPELSIQMDQQLFSYSFSPEVEFRTLRSLVLGKVTETLDLDPEVARANTLGFVGCLSSVQYNHIAPLKAALRHASIAPVTVQKTLTESSCGSMVDSDVNAVTTVHSLSDSFGKTDDHEPLQNAVRSDSAVIGGVIAVVTFITFCVIGIMTRFLYQHKQSHRTNQMKKEYPENLDNSFRNEIDLQNTATECKREYFI", "length": 1304 }, "evidence": [ { "id": "A0A5G2RHF4", "url": "https://omabrowser.org/oma/group/A0A5G2RHF4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WYK1-1", "protein_name": "Contactin-associated protein-like 5", "gene_name": "CNTNAP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSLPRLTSVLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSPAQLNWRVGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIWTFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYIDSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDYGGSMEQLEAVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLDESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYGDRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVTVHGTLTESSCGFMVDSDVNAVTTVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTRFLYQHKQSHRTSQMKEKEYPENLDSSFRNEIDLQNTVSECKREYFI", "length": 1306 }, "evidence": [ { "id": "A0A5G2RHF4", "url": "https://omabrowser.org/oma/group/A0A5G2RHF4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q94887-1", "protein_name": "Neurexin-4", "gene_name": "Nrx-IV", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRPPRSNTKAAFSSLQFGLLCLLLLVNNGIKSVQADAFTDYFSDYDCNQPLMERAVLTATSSLTERGPDKARLNGNAAWTPVENTYNHFLTLDLGDPRMVRKIATMGRMHTDEFVTEYIVQYSDDGEFWRSYVNPTSEPQMFKGNSDGNSIHYNVFEVPIIAQWVRINPTRWHDRISMRVELYGCDYISENLYFNGTGLVRYDLRREPITSTKESIRFRFKTAFANGVMMYSRGTQGDYYALQLKDNKMVLNLDLGSRVMTSLSVGSLLDDNVWHDVVISRNQRDIIFSVDRVIVRGRIQGEFTRLNLNRELYLGGVPNVQEGLIVQQNFSGCLENIYFNSTNFIRVMKDSTELGEGYLFTRVNTIYACPSPPIYPVTFTTRSSFVRLKGYENSQRLNVSFYFRTYEETGVMLHHDFYSGGYLKVFLEFGKVKIDLKVKDKARIILDNYDDQFNDGKWHSFVISIEKNRLILNIDQRPMTTTKSMQVATGAQYYIAGGKDKNGFVGCMRLISVDGNYKLPQDWVKGEEVCCGDDVVVDACQMIDRCNPNPCQHKGLCHQNSREFFCDCGHTGYAGAVCHTSNNPLSCLALKNVQHVQQRVNLNLDVDGSGPLEPFPVTCEFYSDGRVITTLSHSQEHTTTVDGFQEPGSFEQSIMYDANQLQIEALLNRSHSCWQRLSYSCRSSRLFNSPSEAGNFRPFSWWISRHNQPMDYWAGALPGSRKCECGILGKCHDPTKWCNCDSNSLEWMEDGGDIREKEYLPVRAVKFGDTGTPLDEKMGRYTLGPLRCEGDDLFSNVVTFRIADASINLPPFDMGHSGDIYLEFRTTQENSVIFHATGPTDYIKLSLNGGNKLQFQYQAGSGPLGVNVGTSYHLNDNNWHTVSVERNRKEARLVVDGSIKAEVREPPGPVRALHLTSDLVIGATTEYRDGYVGCIRALLLNGKMVDLKEYSKRGLYGISTGCVGRCESNPCLNNGTCIERYDGYSCDCRWSAFKGPICADEIGVNLRSSSIIRYEFEGSFRSTIAENIRVGFTTTIPKGFLLGFSSNLTGEYLTIQISNSGHLRCVFDFGFERQEIIFPKKHFGLGQYHDMHFMRKNGGSTVVLKVDNYEPVEYNFDIKASADAQFNNIQYMYIGKNESMTDGFVGCVSRVQFDDIYPLKLMFQQNPPKNVKSLGTQLTEDFCGVEPVTHPPIEIETRPPPLVDEEKLRKAYNEVDSVLLACLLVILFLLLILMFFLIGRYLHRHKGDYLTHEDQGADGADDPDDAVLHSTTGHQVRKRTEIFI", "length": 1284 }, "evidence": [ { "id": "A0A5G2RHF4", "url": "https://omabrowser.org/oma/group/A0A5G2RHF4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHF4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHF4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHF4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHF4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHF4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHF4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1020, "end_pos": 1022, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1056, "end_pos": 1058, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1070, "end_pos": 1072, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1124, "end_pos": 1126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 746, "end_pos": 748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RHF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 546, "end_pos": 583, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RHF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4" }, { "id": "PS50022", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F5/8 type C", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 174, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RHF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrinogen C-terminal", "eco_id": "ECO_0000259", "start_pos": 582, "end_pos": 634, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RHF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHF4" }, { "id": "PS50025", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50025" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin G", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 360, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1020, "end_pos": 1022 }, { "start_pos": 1056, "end_pos": 1058 }, { "start_pos": 1070, "end_pos": 1072 }, { "start_pos": 1124, "end_pos": 1126 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 622, "end_pos": 624 }, { "start_pos": 746, "end_pos": 748 }, { "start_pos": 768, "end_pos": 770 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1U8N6-1", "uniprot_ac": "A0A5K1U8N6", "uniprot_id": "A0A5K1U8N6_PIG", "mass": { "chemical_mass": 58627.0, "monoisotopic_mass": 58627.0 }, "refseq": {}, "gene_names": [ { "name": "ARFGAP2", "type": "recommended", "evidence": [ { "id": "A0A5K1U8N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor GTPase-activating protein 2", "type": "recommended", "evidence": [ { "id": "A0A5K1U8N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 289", "type": "synonym", "evidence": [ { "id": "A0A5K1U8N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U8N6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARFGAP2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6", "locus": { "chromosome": "2", "start_pos": 15401227, "end_pos": 15390415, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013245", "url": "https://www.ensembl.org/id/ENSSSCG00000013245" } ] } } ], "crossref": [ { "id": "A0A5K1U8N6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1U8N6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013245", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013245", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09029", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09029", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513395", "url": "https://www.ncbi.nlm.nih.gov/gene/100513395", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8D1S8A1", "url": "https://www.orthodb.org/?gene=A0A8D1S8A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45686", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45686", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45686:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45686:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QCP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QCP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R663", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R663", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R663-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R663-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1U8N6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1U8N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0VW53", "url": "https://www.uniprot.org/uniprotkb/A0A8D0VW53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0VW53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0VW53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1S8A1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1S8A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1S8A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1S8A1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAX4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEPSKTEIQTLFKRLRAIPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGSAALARHGTDLWIDNMSSAPSHSPEKKDSDFFSEHTQPPAWSAPATDLSETQQPAPSAESSGLAQPEHGPNMDLLGTSPKASLGQYASWQVWGTWERVELKTSLIGKKKPAAAKKGLGAKKGLGAQKVSSQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPPKYKDNPFSLGESFGSRWDADAAWGMDRMEEKEPEVTISSIRPISERVTNRREVESRSSGLESSEARQKFAGAKAISSDMFFGREVDSEYEARSRLQQLSGSSAISSSDLFGDMDGAHGAGSVSLGNVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQVSYRVASP", "length": 537, "header": "tr|A0A5K1U8N6-1|A0A5K1U8N6_PIG Isoform 1 of ADP-ribosylation factor GTPase-activating protein 2 OS=Sus scrofa OX=9823 GN=ARFGAP2 PE=1 SV=1 CANONICAL=A0A5K1U8N6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QCP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6/entry#A0A5G2QCP2-1", "sequence": { "sequence": "MAAEPSKTEIQTLFKRLRAIPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGSAALARHGTDLWIDNMSSAPSHSPEKKDSDFFSEHTQPPAWSAPATDLSETQQPAPSAESSGLAQPEHGPNMDLLGTSPKASLGQYASWQLGAKKGLGAQKVSSQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPPKYKDNPFSLGESFGSRWDADAAWGMDRMEEKEPEVTISSIRPISERVTNRREVESRSSGLESSEARQKFAGAKAISSDMFFGREVDSEYEARSRLQQLSGSSAISSSDLFGDMDGAHGAGSVSLGNVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQVSYRVASP", "length": 511, "header": "tr|A0A5G2QCP2-1|A0A5G2QCP2_PIG Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 2 OS=Sus scrofa OX=9823 GN=ARFGAP2 PE=1 SV=1 CANONICAL=A0A5K1U8N6-1" }, "locus": { "chromosome": "2", "start_pos": 15399645, "end_pos": 15390626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073169.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073169.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061880.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061880.1" } ] } }, { "isoform_ac": "A0A5G2R663-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6/entry#A0A5G2R663-1", "sequence": { "sequence": "MAAEPSKTEIQTLFKRLRAIPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFISWVPRKA", "length": 70, "header": "tr|A0A5G2R663-1|A0A5K1U8N6_PIG Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 2 OS=Sus scrofa OX=9823 GN=ARFGAP2 PE=1 SV=1 CANONICAL=A0A5K1U8N6-1" }, "locus": { "chromosome": "2", "start_pos": 15395029, "end_pos": 15390626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075600.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075600.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066080.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066080.1" } ] } }, { "isoform_ac": "A0A5K1U8N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6/entry#A0A5K1U8N6-1", "sequence": { "sequence": "MAAEPSKTEIQTLFKRLRAIPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGSAALARHGTDLWIDNMSSAPSHSPEKKDSDFFSEHTQPPAWSAPATDLSETQQPAPSAESSGLAQPEHGPNMDLLGTSPKASLGQYASWQVWGTWERVELKTSLIGKKKPAAAKKGLGAKKGLGAQKVSSQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPPKYKDNPFSLGESFGSRWDADAAWGMDRMEEKEPEVTISSIRPISERVTNRREVESRSSGLESSEARQKFAGAKAISSDMFFGREVDSEYEARSRLQQLSGSSAISSSDLFGDMDGAHGAGSVSLGNVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQVSYRVASP", "length": 537, "header": "tr|A0A5K1U8N6-1|A0A5K1U8N6_PIG Isoform 1 of ADP-ribosylation factor GTPase-activating protein 2 OS=Sus scrofa OX=9823 GN=ARFGAP2 PE=1 SV=1 CANONICAL=A0A5K1U8N6-1" }, "locus": { "chromosome": "2", "start_pos": 15399645, "end_pos": 15390626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027492.4", "url": "https://www.ensembl.org/id/ENSSSCT00000027492.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023917.3", "url": "https://www.ensembl.org/id/ENSSSCP00000023917.3" } ] } }, { "isoform_ac": "A0A8D0VW53-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6/entry#A0A8D0VW53-1", "sequence": { "sequence": "MAAEPSKTEIQTLFKRLRAIPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGSAALARHGTDLWIDNMSSAPSHSPEKKDSDFFSEHTQPPAWSAPATDLSETQQPAPSAESSGLAQPEHGPNMDLLGTSPKASLELKTSLIGKKKPAAAKKGLGAKKGLGAQKVSSQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPPKYKDNPFSLGESFGSRWDADAAWGMDRMEEKEPEVTISSIRPISERVTNRREVESRSSGLESSEARQKFAGAKAISSDMFFGREVDSEVAYLWGMCCPRLTLPSLSRVSSLWPGRWLCWPMV", "length": 477, "header": "tr|A0A8D0VW53-1|A0A5K1U8N6_PIG Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 2 OS=Sus scrofa OX=9823 GN=ARFGAP2 PE=1 SV=1 CANONICAL=A0A5K1U8N6-1" }, "locus": { "chromosome": "2", "start_pos": 15399528, "end_pos": 15390626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014465.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014465.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014073.4", "url": "https://www.ensembl.org/id/ENSSSCP00000014073.4" } ] } }, { "isoform_ac": "A0A8D1S8A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6/entry#A0A8D1S8A1-1", "sequence": { "sequence": "MAAEPSKTEIQTLFKRLRAIPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGSAALARHGTDLWIDNMSSAPSHSPEKKDSDFFSEHTQPPAWSAPATDLSETQQPAPSAESSGLAQPEHGPNMDLLGTSPKASLESMYLSPKGTLPARELKTSLIGKKKPAAAKKGLGAKKGLGAQKVSSQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPPKYKDNPFSLGESFGSRWDADAAWGMDRMEEKEPEVTISSIRPISERVTNRREVESRSSGLESSEARQKFAGAKAISSDMFFGREVDSEYEARSRLQQLSGSSAISSSDLFGDMDGAHGAGSVSLGNVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY", "length": 534, "header": "tr|A0A8D1S8A1-1|A0A5K1U8N6_PIG Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 2 OS=Sus scrofa OX=9823 GN=ARFGAP2 PE=1 SV=1 CANONICAL=A0A5K1U8N6-1" }, "locus": { "chromosome": "2", "start_pos": 15400025, "end_pos": 15390626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062485.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062485.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038641.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038641.1" } ] } }, { "isoform_ac": "A0A8W4FAX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6/entry#A0A8W4FAX4-1", "sequence": { "sequence": "MAAEPSKTEIQTLFKRLRAIPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGSAALARHGTDLWIDNMSSAPSHSPEKKDSDFFSEHTQPPAWSAPATDLSETQQPAPSAESSGLAQPEHGPNMDLLGTSPKASLELKTSLIGKKKPAAAKKGLGAKKGLGAQKVSSQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPPKYKDNPFSLGESFGSRWDADAAWGMDRMEEKEPEVTISSIRPISERVTNRREVESRSSGLESSEARQKFAGAKAISSDMFFGREVDSEYEARSRLQQLSGSVSLGNVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY", "length": 500, "header": "tr|A0A8W4FAX4-1|A0A5K1U8N6_PIG Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 2 OS=Sus scrofa OX=9823 GN=ARFGAP2 PE=1 SV=1 CANONICAL=A0A5K1U8N6-1" }, "locus": { "chromosome": "2", "start_pos": 15400025, "end_pos": 15390626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105226.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105226.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075443.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075443.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0VW53", "url": "https://www.uniprot.org/uniprotkb/A0A8D0VW53" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-SSC-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U8N6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U8N6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U8N6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U8N6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U8N6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6" } ], "pmid": "" }, { "name": "COPI coating of Golgi vesicle", "id": "GO:0048205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048205", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U8N6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1U8N6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 537, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1U8N6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1U8N6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1U8N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8N6" }, { "id": "PS50115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 117, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RHZ7-1", "uniprot_ac": "A0A5G2RHZ7", "uniprot_id": "A0A5G2RHZ7_PIG", "mass": { "chemical_mass": 44827.0, "monoisotopic_mass": 44827.0 }, "refseq": { "ac": "XP_020936539", "name": "heat shock transcription factor, Y-linked-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936539" }, "gene_names": [ { "name": "LOC110257873", "type": "synonym", "evidence": [ { "id": "XP_020936539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936539" } ] } ], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RHZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHZ7/entry#names_and_taxonomy" } ] }, { "name": "heat shock transcription factor, Y-linked-like", "type": "synonym", "evidence": [ { "id": "XP_020936539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936539" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHZ7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHZ7", "locus": {} } ], "crossref": [ { "id": "A0A5G2RHZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RHZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000051215", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000051215", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110257873", "url": "https://www.ncbi.nlm.nih.gov/gene/110257873", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110257873", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257873", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RHZ7", "url": "https://www.orthodb.org/?gene=A0A5G2RHZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020936539", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936539", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RHZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHAPTEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQVEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFNRGCPHLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHLISNFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQAAAHPWFLMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2RHZ7-1|A0A5G2RHZ7_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RHZ7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RHZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHZ7/entry#A0A5G2RHZ7-1", "sequence": { "sequence": "MAHAPTEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQVEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFNRGCPHLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHLISNFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQAAAHPWFLMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402, "header": "tr|A0A5G2RHZ7-1|A0A5G2RHZ7_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RHZ7-1" }, "locus": { "chromosome": "Y", "start_pos": 20444330, "end_pos": 20442702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086023.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086023.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071082.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071082.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "ssc:110257873", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257873", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHZ7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHZ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RHZ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RHZ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RHZ7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RHZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHZ7" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 194, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A5G2RIC0-1", "uniprot_ac": "A0A5G2RIC0", "uniprot_id": "A0A5G2RIC0_PIG", "mass": { "chemical_mass": 126710.0, "monoisotopic_mass": 126710.0 }, "refseq": {}, "gene_names": [ { "name": "IPO5", "type": "recommended", "evidence": [ { "id": "A0A5G2RIC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ] } ], "protein_names": [ { "name": "Importin 5", "type": "synonym", "evidence": [ { "id": "A0A5G2RIC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IPO5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0", "locus": { "chromosome": "11", "start_pos": 67060551, "end_pos": 67004109, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009509", "url": "https://www.ensembl.org/id/ENSSSCG00000009509" } ] } } ], "crossref": [ { "id": "A0A5G2RIC0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009509", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009509", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041389", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041389", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10527", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10527", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02985", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02985", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18808", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18808", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18816", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18816", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18829", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18829", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RIC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP44", "url": "https://www.uniprot.org/uniprotkb/F1RP44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP44-1", "url": "https://www.uniprot.org/uniprotkb/F1RP44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGQSKITFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPTLPTDVQTAIKSELLMIIQMETQSSMRKKICDIAAELARNLIDEDGNNQWPEGLKFLFDSVSSQNMGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAAMLRKHTSIVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVSNTSANTQIKLVGSGVAFQSVCVCDFISQVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFSDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVPLLKFYFHDGVRVAAAESMPLLLECARVRGPEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDVVEHCSPASFKYAEYFLRPMLQYVCDSSPEVRQAAAYGLGVMAQYGGDNYRPFCTEALPLLVRVIQSADSKTKENVNATENCISAVGKIMKFKPDCVNVEEVLPHWLSWLPLHEDKEEAVQTFNYLCDLIESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQELLNSA", "length": 1127, "header": "tr|A0A5G2RIC0-1|A0A5G2RIC0_PIG Isoform 1 of Importin 5 OS=Sus scrofa OX=9823 GN=IPO5 PE=1 SV=1 CANONICAL=A0A5G2RIC0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RIC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0/entry#A0A5G2RIC0-1", "sequence": { "sequence": "MAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGQSKITFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPTLPTDVQTAIKSELLMIIQMETQSSMRKKICDIAAELARNLIDEDGNNQWPEGLKFLFDSVSSQNMGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAAMLRKHTSIVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVSNTSANTQIKLVGSGVAFQSVCVCDFISQVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFSDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVPLLKFYFHDGVRVAAAESMPLLLECARVRGPEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDVVEHCSPASFKYAEYFLRPMLQYVCDSSPEVRQAAAYGLGVMAQYGGDNYRPFCTEALPLLVRVIQSADSKTKENVNATENCISAVGKIMKFKPDCVNVEEVLPHWLSWLPLHEDKEEAVQTFNYLCDLIESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQELLNSA", "length": 1127, "header": "tr|A0A5G2RIC0-1|A0A5G2RIC0_PIG Isoform 1 of Importin 5 OS=Sus scrofa OX=9823 GN=IPO5 PE=1 SV=1 CANONICAL=A0A5G2RIC0-1" }, "locus": { "chromosome": "11", "start_pos": 67059313, "end_pos": 67019320, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082302.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082302.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071292.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071292.1" } ] } }, { "isoform_ac": "F1RP44-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0/entry#F1RP44-1", "sequence": { "sequence": "MAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGQSKITFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPTLPTDVQTAIKSELLMIIQMETQSSMRKKICDIAAELARNLIDEDGNNQWPEGLKFLFDSVSSQNMGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAAMLRKHTSIVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFSDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVPLLKFYFHDGVRVAAAESMPLLLECARVRGPEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDVVEHCSPASFKYAEYFLRPMLQYVCDSSPEVRQAAAYGLGVMAQYGGDNYRPFCTGTCAYVAACMCNPVAPTLFPFPGPKHDTLALLFPLFTHLVHSI", "length": 988, "header": "tr|F1RP44-1|A0A5G2RIC0_PIG Computationally mapped isoform of Importin 5 OS=Sus scrofa OX=9823 GN=IPO5 PE=1 SV=3 CANONICAL=A0A5G2RIC0-1" }, "locus": { "chromosome": "11", "start_pos": 67056310, "end_pos": 67019320, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010426.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010426.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010155.4", "url": "https://www.ensembl.org/id/ENSSSCP00000010155.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RP44", "url": "https://www.uniprot.org/uniprotkb/F1RP44" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of protein import into nucleus", "id": "GO:0042307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042307", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" }, { "name": "ribosomal protein import into nucleus", "id": "GO:0006610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006610", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" }, { "name": "cellular response to amino acid stimulus", "id": "GO:0071230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" }, { "name": "NLS-bearing protein import into nucleus", "id": "GO:0006607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006607", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" }, { "name": "cytoplasmic pattern recognition receptor signaling pathway", "id": "GO:0002753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002753", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" }, { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIC0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1061, "end_pos": 1063, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 997, "end_pos": 999, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RIC0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1127, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RIC0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIC0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RIC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIC0" }, { "id": "PS50166", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50166" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Importin N-terminal", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 99, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1061, "end_pos": 1063 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 444, "end_pos": 446 }, { "start_pos": 498, "end_pos": 500 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 680, "end_pos": 682 }, { "start_pos": 997, "end_pos": 999 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RIH3-1", "uniprot_ac": "A0A5G2RIH3", "uniprot_id": "A0A5G2RIH3_PIG", "mass": { "chemical_mass": 36162.0, "monoisotopic_mass": 36162.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RIH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3", "locus": {} } ], "crossref": [ { "id": "A0A5G2RIH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13954", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13954", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RIH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RIH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVGNQTIATEFIFLGLSDVPYLRLALFTMFLTIYIFSLMGNALIIFIVLMDSTLQTPMYIFLGNLSFLEIWYTTATVPKLLATCLSDVVTISVSSCIAQYYFFFSLGATECILLAVMAYDRYLAICSPLRYSFLMSVQVCMQFSALSWIGGFIAPALPTILVSYLSFCGSQKINHFFCDSDPIFKLSCSDTFLVEALGYTCSSIVILSSFLLTMSSYGHIVVTIIRLSSREARKKTFSTCASHLTVVTIYYGTIIFAYVRPPAKHNLTMGKVVSVFYCVVTPLLNPLVYTLRNKDVKKAFRKVLAQKRLLLMNINIHGEFH", "length": 322, "header": "tr|A0A5G2RIH3-1|A0A5G2RIH3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RIH3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RIH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3/entry#A0A5G2RIH3-1", "sequence": { "sequence": "MKVGNQTIATEFIFLGLSDVPYLRLALFTMFLTIYIFSLMGNALIIFIVLMDSTLQTPMYIFLGNLSFLEIWYTTATVPKLLATCLSDVVTISVSSCIAQYYFFFSLGATECILLAVMAYDRYLAICSPLRYSFLMSVQVCMQFSALSWIGGFIAPALPTILVSYLSFCGSQKINHFFCDSDPIFKLSCSDTFLVEALGYTCSSIVILSSFLLTMSSYGHIVVTIIRLSSREARKKTFSTCASHLTVVTIYYGTIIFAYVRPPAKHNLTMGKVVSVFYCVVTPLLNPLVYTLRNKDVKKAFRKVLAQKRLLLMNINIHGEFH", "length": 322, "header": "tr|A0A5G2RIH3-1|A0A5G2RIH3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RIH3-1" }, "locus": { "chromosome": "2", "start_pos": 56253151, "end_pos": 56251339, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072228.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072228.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071392.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071392.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIH3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RIH3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 322, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RIH3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIH3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RIH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIH3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 267, "end_pos": 269 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RIK5-1", "uniprot_ac": "A0A5G2RIK5", "uniprot_id": "A0A5G2RIK5_PIG", "mass": { "chemical_mass": 34574.0, "monoisotopic_mass": 34574.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100520607", "type": "recommended", "evidence": [ { "id": "A0A5G2RIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIK5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIK5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100520607", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5", "locus": {} } ], "crossref": [ { "id": "A0A5G2RIK5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIK5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000042634", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042634", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RIK5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RIK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METRNNATEYILLGLTQNPHMQKVIFVVCLLIYTVSLGGNVLTIVTITTSPLIGCPMYFFLAHLSFIDACYSCVDTPKLVVDSLYEKKTSTFHGCMMQIFGEHFFAGADIILLTVMAYDRYVAICKPLYYATIMNRWLCGLLVGVSWLGGFLHGFIQILFIFRLPFCGPNVIDHFMCDLISFLKLACTDTHTLVLIVAANSGSLCMLKFLLLVGSYVLILHTLRTQSLEARRKALSTCVSHITAVVIFFVPCIFEYMRPAVTIPIDKAVAEFYTMITPMLNPLICTLRNAQLKNAIRKLFSGKALTGEI", "length": 309, "header": "tr|A0A5G2RIK5-1|A0A5G2RIK5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100520607 PE=3 SV=1 CANONICAL=A0A5G2RIK5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RIK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5/entry#A0A5G2RIK5-1", "sequence": { "sequence": "METRNNATEYILLGLTQNPHMQKVIFVVCLLIYTVSLGGNVLTIVTITTSPLIGCPMYFFLAHLSFIDACYSCVDTPKLVVDSLYEKKTSTFHGCMMQIFGEHFFAGADIILLTVMAYDRYVAICKPLYYATIMNRWLCGLLVGVSWLGGFLHGFIQILFIFRLPFCGPNVIDHFMCDLISFLKLACTDTHTLVLIVAANSGSLCMLKFLLLVGSYVLILHTLRTQSLEARRKALSTCVSHITAVVIFFVPCIFEYMRPAVTIPIDKAVAEFYTMITPMLNPLICTLRNAQLKNAIRKLFSGKALTGEI", "length": 309, "header": "tr|A0A5G2RIK5-1|A0A5G2RIK5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100520607 PE=3 SV=1 CANONICAL=A0A5G2RIK5-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 171479, "end_pos": 170553, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090612.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090612.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071437.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071437.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIK5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIK5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIK5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIK5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RIK5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RIK5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIK5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIK5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RIP1-1", "uniprot_ac": "A0A5G2RIP1", "uniprot_id": "A0A5G2RIP1_PIG", "mass": { "chemical_mass": 47559.0, "monoisotopic_mass": 47559.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100739741", "type": "recommended", "evidence": [ { "id": "A0A5G2RIP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1" } ] } ], "protein_names": [ { "name": "Cytochrome P450 2C23", "type": "recommended", "evidence": [ { "id": "A0A5G2RIP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100739741", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1", "locus": {} } ], "crossref": [ { "id": "A0A5G2RIP1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010546", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010546", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300:SF346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300:SF346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RIP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RIP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELLGITTLALTVYVTCLVFLSVWKKNHKRRRLPPGPTPLPIIGNLMQLNLKDIPASLSKLAKQYGPVCTVYFGSQPAVVLHGYEAVKEALIDQGDEFLGRGIIPIIDDTQGGYGLIFSNGERWKQIRRFSLMTLRNFGMGKRSLEERVQEEAQFLVEELRKTEAQPFDPTFILSCAPCNVICSILFNDRFHYDNETFLSLMNLLNANFRHLNSPWIQIYNLWPQIIKHLPGEHRTFSKRLKDCRSFILEKVKEHEKSPNLNNPQDYIDCFLSKMEQEKQNPDSEFHLKNLINSGTNLYGLLLLMKHPEVQAKVHEEIDRVIGRSQRPCMQDKMKLPYTEAVLHEIQRYIALVPSNVPHATVRDTKFREYIIPKVSSVWGSWLGWKGQGERCLSSVPGRGSWEEQGQSHTAWL", "length": 413, "header": "tr|A0A5G2RIP1-1|A0A5G2RIP1_PIG Isoform 1 of Cytochrome P450 2C23 OS=Sus scrofa OX=9823 GN=LOC100739741 PE=1 SV=2 CANONICAL=A0A5G2RIP1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RIP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1/entry#A0A5G2RIP1-1", "sequence": { "sequence": "MELLGITTLALTVYVTCLVFLSVWKKNHKRRRLPPGPTPLPIIGNLMQLNLKDIPASLSKLAKQYGPVCTVYFGSQPAVVLHGYEAVKEALIDQGDEFLGRGIIPIIDDTQGGYGLIFSNGERWKQIRRFSLMTLRNFGMGKRSLEERVQEEAQFLVEELRKTEAQPFDPTFILSCAPCNVICSILFNDRFHYDNETFLSLMNLLNANFRHLNSPWIQIYNLWPQIIKHLPGEHRTFSKRLKDCRSFILEKVKEHEKSPNLNNPQDYIDCFLSKMEQEKQNPDSEFHLKNLINSGTNLYGLLLLMKHPEVQAKVHEEIDRVIGRSQRPCMQDKMKLPYTEAVLHEIQRYIALVPSNVPHATVRDTKFREYIIPKVSSVWGSWLGWKGQGERCLSSVPGRGSWEEQGQSHTAWL", "length": 413, "header": "tr|A0A5G2RIP1-1|A0A5G2RIP1_PIG Isoform 1 of Cytochrome P450 2C23 OS=Sus scrofa OX=9823 GN=LOC100739741 PE=1 SV=2 CANONICAL=A0A5G2RIP1-1" }, "locus": { "chromosome": "14", "start_pos": 111262271, "end_pos": 111245002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085776.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085776.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071498.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071498.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 38, "start_aa": "Thr", "end_pos": 38, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr38", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "xenobiotic catabolic process", "id": "GO:0042178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042178", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1" } ], "pmid": "" }, { "name": "epoxygenase P450 pathway", "id": "GO:0019373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019373", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIP1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RIP1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 413, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RIP1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIP1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 38 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RIT1-1", "uniprot_ac": "A0A5G2RIT1", "uniprot_id": "A0A5G2RIT1_PIG", "mass": { "chemical_mass": 35358.0, "monoisotopic_mass": 35358.0 }, "refseq": {}, "gene_names": [ { "name": "OR2T27", "type": "recommended", "evidence": [ { "id": "A0A5G2RIT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RIT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OR2T27", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1", "locus": { "chromosome": "2", "start_pos": 53163848, "end_pos": 53164789, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031699", "url": "https://www.ensembl.org/id/ENSSSCG00000031699" } ] } } ], "crossref": [ { "id": "A0A5G2RIT1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RIT1", "url": "https://www.orthodb.org/?gene=A0A5G2RIT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RIT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RIT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEWGNYSIYADFVLLGLFSNTRFPWLLFVFIFLVFVISIASNTIMIILIHVDSRLHTPMYFLLSQLSIMDILYISTIVPKMLVDQMVGQRAISFAGCTAQHFLYLTLAGAEFFLLGLMSYDRYIAICNPLRYPVLMSRKVCLLIVLLAWLGGSIDGFLLTPITMQFPFCSSREINHFFCEVPALLKLSCMDTSAYETSMYICCIMMLLIPFSVISASYTRILITVYRMSEAEGRRKAVATCSSHMVVVTLFYGAAMYTYVLPHSYHTPEQDKAVSAFYTILTPLLNPLIYSLRNKDVTGALQKALGSCLCSAQ", "length": 313, "header": "tr|A0A5G2RIT1-1|A0A5G2RIT1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR2T27 PE=3 SV=1 CANONICAL=A0A5G2RIT1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RIT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1/entry#A0A5G2RIT1-1", "sequence": { "sequence": "MEWGNYSIYADFVLLGLFSNTRFPWLLFVFIFLVFVISIASNTIMIILIHVDSRLHTPMYFLLSQLSIMDILYISTIVPKMLVDQMVGQRAISFAGCTAQHFLYLTLAGAEFFLLGLMSYDRYIAICNPLRYPVLMSRKVCLLIVLLAWLGGSIDGFLLTPITMQFPFCSSREINHFFCEVPALLKLSCMDTSAYETSMYICCIMMLLIPFSVISASYTRILITVYRMSEAEGRRKAVATCSSHMVVVTLFYGAAMYTYVLPHSYHTPEQDKAVSAFYTILTPLLNPLIYSLRNKDVTGALQKALGSCLCSAQ", "length": 313, "header": "tr|A0A5G2RIT1-1|A0A5G2RIT1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR2T27 PE=3 SV=1 CANONICAL=A0A5G2RIT1-1" }, "locus": { "chromosome": "2", "start_pos": 53164789, "end_pos": 53163851, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038244.2", "url": "https://www.ensembl.org/id/ENSSSCT00000038244.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071563.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071563.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RIT1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RIT1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIT1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RIT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIT1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RIV2-1", "uniprot_ac": "A0A5G2RIV2", "uniprot_id": "A0A5G2RIV2_PIG", "mass": { "chemical_mass": 64623.0, "monoisotopic_mass": 64623.0 }, "refseq": {}, "gene_names": [ { "name": "HAS1", "type": "recommended", "evidence": [ { "id": "A0A5G2RIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2" } ] } ], "protein_names": [ { "name": "Hyaluronan synthase 1", "type": "recommended", "evidence": [ { "id": "A0A5G2RIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.212", "type": "synonym", "evidence": [ { "id": "A0A5G2RIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2/entry#names_and_taxonomy" } ] }, { "name": "Hyaluronate synthase 1", "type": "synonym", "evidence": [ { "id": "A0A5G2RIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2/entry#names_and_taxonomy" } ] }, { "name": "Hyaluronic acid synthase 1", "type": "synonym", "evidence": [ { "id": "A0A5G2RIV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential for the synthesis of hyaluronan, a major component of most extracellular matrices that has a structural role in tissue architecture and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate.", "evidence": [ { "database": "UniProtKB", "id": "F1RP83", "url": "https://www.uniprot.org/uniprotkb/F1RP83#function" }, { "database": "UniProtKB", "id": "ARBA00094441", "url": "https://www.uniprot.org/uniprotkb/ARBA00094441#function" }, { "database": "UniProtKB", "id": "A0A5G2RIV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HAS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2", "locus": { "chromosome": "6", "start_pos": 58313486, "end_pos": 58302799, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003239", "url": "https://www.ensembl.org/id/ENSSSCG00000003239" } ] } } ], "crossref": [ { "id": "A0A5G2RIV2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIV2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003239", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003239", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22913", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22913", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22913:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22913:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13641", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13641", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2142845", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2142845", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "12528", "url": "https://www.rhea-db.org/rhea/12528", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "20465", "url": "https://www.rhea-db.org/rhea/20465", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RIV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RIV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP83", "url": "https://www.uniprot.org/uniprotkb/F1RP83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP83-1", "url": "https://www.uniprot.org/uniprotkb/F1RP83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQDVPKPSPAARHCSSLARRVLTIAFALLILGLMTWAYAAGVPLASDRFGLLAFGLYGAFLSAHLVAQSLFAYLEHRRVAAAARGPPDAATARSVALTISAYQEDPAYLRQCLVSARALLYPRARLRVVMVVDGNRAEDLYMVDMFREVFADEDPATYVWDGNYHQPWEPAAAGAAGAYREVEAEDPGRLAVETLVRTRRCVCVAQRWGGKREVMYTAFKALGDSVDYVQVCDSDTRLDPLALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYFHCVSCISGPLGLYRNNLLQQFLEAWYNQKFLGTHCTFGDDRHLTNRMLSMGYATKYTSRSRCYSETPSSFLRWLSQQTRWSKSYFREWLYNALWWHRHHAWMTYEAVVSGLFPFFVAATVLRLFYAGRPWALLWVLLCVQGVALAKAAFAAWLRGCLWMLLLSLYAPLYMGGLLPAKFLALATMNQSGWGTSGRRQLAANYVPVLPLALWALLLLGGLVRSVVHEARADWSGPSRAAEARHLAVGAGAYLGYWAIMLTLYWVGVRRLCRRRAGGYRVQV", "length": 575, "header": "tr|A0A5G2RIV2-1|A0A5G2RIV2_PIG Isoform 1 of Hyaluronan synthase 1 OS=Sus scrofa OX=9823 GN=HAS1 PE=3 SV=2 CANONICAL=A0A5G2RIV2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RIV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2/entry#A0A5G2RIV2-1", "sequence": { "sequence": "MRQDVPKPSPAARHCSSLARRVLTIAFALLILGLMTWAYAAGVPLASDRFGLLAFGLYGAFLSAHLVAQSLFAYLEHRRVAAAARGPPDAATARSVALTISAYQEDPAYLRQCLVSARALLYPRARLRVVMVVDGNRAEDLYMVDMFREVFADEDPATYVWDGNYHQPWEPAAAGAAGAYREVEAEDPGRLAVETLVRTRRCVCVAQRWGGKREVMYTAFKALGDSVDYVQVCDSDTRLDPLALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYFHCVSCISGPLGLYRNNLLQQFLEAWYNQKFLGTHCTFGDDRHLTNRMLSMGYATKYTSRSRCYSETPSSFLRWLSQQTRWSKSYFREWLYNALWWHRHHAWMTYEAVVSGLFPFFVAATVLRLFYAGRPWALLWVLLCVQGVALAKAAFAAWLRGCLWMLLLSLYAPLYMGGLLPAKFLALATMNQSGWGTSGRRQLAANYVPVLPLALWALLLLGGLVRSVVHEARADWSGPSRAAEARHLAVGAGAYLGYWAIMLTLYWVGVRRLCRRRAGGYRVQV", "length": 575, "header": "tr|A0A5G2RIV2-1|A0A5G2RIV2_PIG Isoform 1 of Hyaluronan synthase 1 OS=Sus scrofa OX=9823 GN=HAS1 PE=3 SV=2 CANONICAL=A0A5G2RIV2-1" }, "locus": { "chromosome": "6", "start_pos": 58313126, "end_pos": 58303283, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070737.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070737.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071599.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071599.2" } ] } }, { "isoform_ac": "F1RP83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2/entry#F1RP83-1", "sequence": { "sequence": "LPRHCSSLARRVLTIAFALLILGLMTWAYAAGVPLASDRFGLLAFGLYGAFLSAHLVAQSLFAYLEHRRVAAAARRAAAVALTISAYQEDPAYLRQCLVSARALLYPRARLRVVMVVDGNRAEDLYMVDMFREVFADEDPATYVWDGNYHQPWEPAAAGAAGAYREVEAEDPGRLAVETLVRTRRCVCVAQRWGGKREVMYTAFKALGDSVDYVQVCDSDTRLDPLALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYFHCVSCISGPLGLYRNNLLQQFLEAWYNQKFLGTHCTFGDDRHLTNRMLSMGYATKYTSRSRCYSETPSSFLRWLSQQTRWSKSYFREWLYNALWWHRHHAWMTYEAVVSGLFPFFVAATVLRLFYAGRPWALLWVLLCVQGVALAKAAFAAWLRGCLWMLLLSLYAPLYMGGLLPAKFLALATMNQSGWGTSGRRQLAANYVPVLPLALWALLLLGGLVRSVVHEARADWSGPSRAAEARHLAVGAGAYLGYWAIMLTLYWVGVRRLCRRRAGGYRVQV", "length": 559, "header": "tr|F1RP83-1|A0A5G2RIV2_PIG Computationally mapped isoform of Hyaluronan synthase 1 OS=Sus scrofa OX=9823 GN=HAS1 PE=3 SV=3 CANONICAL=A0A5G2RIV2-1" }, "locus": { "chromosome": "6", "start_pos": 58313126, "end_pos": 58307106, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003598.3", "url": "https://www.ensembl.org/id/ENSSSCT00000003598.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003515.3", "url": "https://www.ensembl.org/id/ENSSSCP00000003515.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RP83", "url": "https://www.uniprot.org/uniprotkb/F1RP83" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2142845", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2142845", "resource": "Reactome", "description": "Hyaluronan metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "polysaccharide biosynthetic process", "id": "GO:0000271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000271", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2" } ], "pmid": "" }, { "name": "extracellular matrix assembly", "id": "GO:0085029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0085029", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2" } ], "pmid": "" }, { "name": "hyaluronan biosynthetic process", "id": "GO:0030213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030213", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2" } ], "pmid": "" }, { "name": "glycosaminoglycan biosynthetic process", "id": "GO:0006024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006024", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hyaluronan synthase activity", "id": "GO:0050501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050501", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIV2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12528", "name": "", "equation": "N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronan](n) + UDP-alpha-D-glucuronate = [hyaluronan](n+1) + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12528", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12528" } ] }, { "id": "20465", "name": "", "equation": "[hyaluronan](n) + UDP-N-acetyl-alpha-D-glucosamine = N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronan](n) + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20465", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20465" } ] }, { "id": "R-SSC-2160851", "name": "HAS1,2,3 mediate the polymerization and export of HA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-ALL-158601", "R-ALL-162756" ], "output_participant_list": [ "R-ALL-2160848", "R-ALL-110096" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2160851", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2160851" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-110096", "participant_name": "UDP [cytosol]", "crossref": [ { "id": "58223", "database": "ChEBI", "url": "" }, { "id": "C00015", "database": "COMPOUND", "url": "" }, { "id": "ZINC000004490939", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-158601", "participant_name": "UDP-GlcA [cytosol]", "crossref": [ { "id": "58052", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215691", "database": "ZINC", "url": "" }, { "id": "C00167", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-162756", "participant_name": "UDP-GlcNAc [cytosol]", "crossref": [ { "id": "57705", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551100", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2160848", "participant_name": "HA [extracellular region]", "crossref": [ { "id": "132153", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RIV2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 575, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RIV2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIV2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 481, "end_pos": 483 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RIZ1-1", "uniprot_ac": "A0A5G2RIZ1", "uniprot_id": "A0A5G2RIZ1_PIG", "mass": { "chemical_mass": 38355.0, "monoisotopic_mass": 38355.0 }, "refseq": {}, "gene_names": [ { "name": "PITPNC1", "type": "recommended", "evidence": [ { "id": "A0A5G2RIZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" } ] } ], "protein_names": [ { "name": "Cytoplasmic phosphatidylinositol transfer protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2RIZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1/entry#names_and_taxonomy" } ] }, { "name": "Mammalian rdgB homolog beta", "type": "synonym", "evidence": [ { "id": "A0A5G2RIZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1/entry#names_and_taxonomy" } ] }, { "name": "Retinal degeneration B homolog beta", "type": "synonym", "evidence": [ { "id": "A0A5G2RIZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidic acid (PA) between membranes. Binds PA derived from the phospholipase D signaling pathway and among the cellular PA species, preferably binds to the C16:0/16:1 and C16:1/18:1 PA species.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1#function" }, { "database": "UniProtKB", "id": "ARBA00055461", "url": "https://www.uniprot.org/uniprotkb/ARBA00055461#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PITPNC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1", "locus": { "chromosome": "12", "start_pos": 14019689, "end_pos": 13741222, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017274", "url": "https://www.ensembl.org/id/ENSSSCG00000017274" } ] } } ], "crossref": [ { "id": "A0A5G2RIZ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIZ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017274", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017274", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08890", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08890", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10658", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10658", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10658:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10658:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "36435", "url": "https://www.rhea-db.org/rhea/36435", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38691", "url": "https://www.rhea-db.org/rhea/38691", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RIZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLKEYRICMPLTVDEYKIGQLYMISKHSHEQSDRGEGVEVVQNEPFEDPHHGNGQFTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTCSFLPKFSIHIETKYEDNKGSNDSIFDNEAKDLEREVCFIDIACDEIPERYYKESEDPKHFKSEKTGRGQLREGWRDSHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGVFPPAISISSIPLLPSSVRSAPSSAPSTPLSTDAPEFLSVPKDRPRKKSAPETLTLPDPEKKATLNLPGIHSSDKPCRPKSE", "length": 332, "header": "tr|A0A5G2RIZ1-1|A0A5G2RIZ1_PIG Isoform 1 of Cytoplasmic phosphatidylinositol transfer protein 1 OS=Sus scrofa OX=9823 GN=PITPNC1 PE=1 SV=1 CANONICAL=A0A5G2RIZ1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RIZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1/entry#A0A5G2RIZ1-1", "sequence": { "sequence": "MLLKEYRICMPLTVDEYKIGQLYMISKHSHEQSDRGEGVEVVQNEPFEDPHHGNGQFTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTCSFLPKFSIHIETKYEDNKGSNDSIFDNEAKDLEREVCFIDIACDEIPERYYKESEDPKHFKSEKTGRGQLREGWRDSHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGVFPPAISISSIPLLPSSVRSAPSSAPSTPLSTDAPEFLSVPKDRPRKKSAPETLTLPDPEKKATLNLPGIHSSDKPCRPKSE", "length": 332, "header": "tr|A0A5G2RIZ1-1|A0A5G2RIZ1_PIG Isoform 1 of Cytoplasmic phosphatidylinositol transfer protein 1 OS=Sus scrofa OX=9823 GN=PITPNC1 PE=1 SV=1 CANONICAL=A0A5G2RIZ1-1" }, "locus": { "chromosome": "12", "start_pos": 14015241, "end_pos": 13742065, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074870.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074870.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071669.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071669.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "phosphatidic acid transfer activity", "id": "GO:1990050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990050", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" } ], "pmid": "" }, { "name": "phosphatidylglycerol binding", "id": "GO:1901611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901611", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" } ], "pmid": "" }, { "name": "phosphatidic acid binding", "id": "GO:0070300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070300", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" } ], "pmid": "" }, { "name": "phosphatidylinositol transfer activity", "id": "GO:0008526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008526", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" } ], "pmid": "" }, { "name": "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "id": "GO:1902635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902635", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36435", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphate(in) = a 1,2-diacyl-sn-glycero-3-phosphate(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "36435", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36435" } ] }, { "id": "38691", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "38691", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38691" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RIZ1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 332, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RIZ1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RIZ1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RIZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RIZ1" }, { "id": "PF02121", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02121" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidylinositol transfer protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 243, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RJ62-1", "uniprot_ac": "A0A5G2RJ62", "uniprot_id": "A0A5G2RJ62_PIG", "mass": { "chemical_mass": 46480.0, "monoisotopic_mass": 46480.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110255272", "type": "recommended", "evidence": [ { "id": "A0A5G2RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62" } ] } ], "protein_names": [ { "name": "Keratin, type I cytoskeletal 14", "type": "recommended", "evidence": [ { "id": "A0A5G2RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62/entry#names_and_taxonomy" } ] }, { "name": "Cytokeratin-14", "type": "synonym", "evidence": [ { "id": "A0A5G2RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62/entry#names_and_taxonomy" } ] }, { "name": "Keratin-14", "type": "synonym", "evidence": [ { "id": "A0A5G2RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62#function" }, { "database": "UniProtKB", "id": "ARBA00037229", "url": "https://www.uniprot.org/uniprotkb/ARBA00037229#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110255272", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62", "locus": {} } ], "crossref": [ { "id": "A0A5G2RJ62", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RJ62", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017448", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017448", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF368", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF368", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RJ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATCSRQFTSSSSMKGSCGIGGGSSRISSVLGGGSYQAPSAYGGLSVTSSRYSSGGVCGLGGGYGGGFSSSSSFGGALGSGFGGGYGGGLGAGFGGGFGGGFGGGFGGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAESKDYSPYFKTIEDLRNKILVATVDNANVVLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEAWFFSKTEELNREVATNSELVQSGKSEISELRRTVQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQELISGVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAQ", "length": 427, "header": "tr|A0A5G2RJ62-1|A0A5G2RJ62_PIG Isoform 1 of Keratin, type I cytoskeletal 14 OS=Sus scrofa OX=9823 GN=LOC110255272 PE=3 SV=1 CANONICAL=A0A5G2RJ62-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RJ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62/entry#A0A5G2RJ62-1", "sequence": { "sequence": "MATCSRQFTSSSSMKGSCGIGGGSSRISSVLGGGSYQAPSAYGGLSVTSSRYSSGGVCGLGGGYGGGFSSSSSFGGALGSGFGGGYGGGLGAGFGGGFGGGFGGGFGGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAESKDYSPYFKTIEDLRNKILVATVDNANVVLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEAWFFSKTEELNREVATNSELVQSGKSEISELRRTVQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQELISGVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAQ", "length": 427, "header": "tr|A0A5G2RJ62-1|A0A5G2RJ62_PIG Isoform 1 of Keratin, type I cytoskeletal 14 OS=Sus scrofa OX=9823 GN=LOC110255272 PE=3 SV=1 CANONICAL=A0A5G2RJ62-1" }, "locus": { "chromosome": "12", "start_pos": 21040814, "end_pos": 21037405, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080487.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080487.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071809.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071809.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "keratinocyte differentiation", "id": "GO:0030216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030216", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62" } ], "pmid": "" }, { "name": "morphogenesis of an epithelium", "id": "GO:0002009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJ62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RJ62-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 427, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RJ62-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RJ62" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ62" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 427, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RJE9-1", "uniprot_ac": "A0A5G2RJE9", "uniprot_id": "A0A5G2RJE9_PIG", "mass": { "chemical_mass": 49942.0, "monoisotopic_mass": 49942.0 }, "refseq": { "ac": "XP_003122079", "name": "tripartite motif-containing protein 14 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122079" }, "gene_names": [ { "name": "TRIM14", "type": "recommended", "evidence": [ { "id": "A0A5G2RJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9" } ] }, { "name": "TRIM14", "type": "synonym", "evidence": [ { "id": "XP_003122079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122079" } ] } ], "protein_names": [ { "name": "Tripartite motif containing 14", "type": "synonym", "evidence": [ { "id": "A0A5G2RJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9/entry#names_and_taxonomy" } ] }, { "name": "tripartite motif-containing protein 14 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003122079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122079" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TRIM14", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9", "locus": { "chromosome": "1", "start_pos": 239912126, "end_pos": 239945073, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000033222", "url": "https://www.ensembl.org/id/ENSSSCG00000033222" } ] } } ], "crossref": [ { "id": "ENSSSCG00000033222", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033222", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13738", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13738", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100151834", "url": "https://www.ncbi.nlm.nih.gov/gene/100151834", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100151834", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151834", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WWIGAAY", "url": "https://omabrowser.org/oma/group/WWIGAAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RJE9", "url": "https://www.orthodb.org/?gene=A0A5G2RJE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003122079", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122079", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RJE9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAAALSGTPEGLGRGDPEEAHGRRCREHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVCLVLEEAARVQNLTQECLMQLASKKQQQVGNITQIEDAAEKLKAHAESSKTWLTGKFTELRLLLDEEEALAKKFIDKNTQLALQVYREQIESCGEQINVMNSLSDKVWSISQERNPIQLLQEYMAAEQQIQQQLSLGELCHPMPLSFEPVKSLFKGLVDAMQSLLQTPLDVRLKEDMNCQLSGSSSAKPGSLLKTSPSPQRSLFLKYARTPTLEPDTMHARLRLSADRLTVRCGLFGRLGPTPTLCFDSLWQVLGRDCFAAGRHYWEVDVQEAGIGWWVGAAYGSLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRLRDDPDRLGVFLDYEAGVLAFYDVSGGMSHLHTFRAAFQEPLYPALRLWEGAISIPRLP", "length": 445, "header": "tr|A0A5G2RJE9-1|A0A5G2RJE9_PIG Isoform 1 of Tripartite motif containing 14 OS=Sus scrofa OX=9823 GN=TRIM14 PE=4 SV=1 CANONICAL=A0A5G2RJE9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RJE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9/entry#A0A5G2RJE9-1", "sequence": { "sequence": "MAGAAALSGTPEGLGRGDPEEAHGRRCREHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVCLVLEEAARVQNLTQECLMQLASKKQQQVGNITQIEDAAEKLKAHAESSKTWLTGKFTELRLLLDEEEALAKKFIDKNTQLALQVYREQIESCGEQINVMNSLSDKVWSISQERNPIQLLQEYMAAEQQIQQQLSLGELCHPMPLSFEPVKSLFKGLVDAMQSLLQTPLDVRLKEDMNCQLSGSSSAKPGSLLKTSPSPQRSLFLKYARTPTLEPDTMHARLRLSADRLTVRCGLFGRLGPTPTLCFDSLWQVLGRDCFAAGRHYWEVDVQEAGIGWWVGAAYGSLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRLRDDPDRLGVFLDYEAGVLAFYDVSGGMSHLHTFRAAFQEPLYPALRLWEGAISIPRLP", "length": 445, "header": "tr|A0A5G2RJE9-1|A0A5G2RJE9_PIG Isoform 1 of Tripartite motif containing 14 OS=Sus scrofa OX=9823 GN=TRIM14 PE=4 SV=1 CANONICAL=A0A5G2RJE9-1" }, "locus": { "chromosome": "1", "start_pos": 239944927, "end_pos": 239918707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062686.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062686.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042696.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042696.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 303, "start_aa": "Thr", "end_pos": 303, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr303", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100151834", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151834", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NMS2-1", "protein_name": "Tripartite motif containing 14", "gene_name": "TRIM14", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAQGQPWVAAGPRGCAVHSGRPLELFCGDCGRCVCALCPALGPHRGHDARLLLQAARDKQELLTVYLRNLEVRKEQQAGNRRSVEQAADDLKAHAATSKQQLLDRVTQLQLLLQEEERLARNVIDEKTQQALEAHGQQVQSCQEELAALEAFSRRIREIQQCSDPIQFLEKCTEIEKEMQDSRRQPEQWHPIPLSFEHILNHYSCLMKFLQSILQKPLEVRLKEDVFGSLNATSKREPGTMLKTMSPVDRMLFLKHARSPTWEYDSLHPRLKLSDDRLVVSCNWRRIFYPCGPQRFDKLWQVLSRDAFLSGSHYWEVDLLHAGAGWWIGAAYPSIGRKGDSESCRLGWNRASWCIKKFDLEYWAFHKGERIPLLIEDDPDRIGVFLDYEAGILSFYNVTDGMTHLHTFRCKFTEPVYPALRLWEGSIGIWKLT", "length": 433 }, "evidence": [ { "id": "A0A5G2RJE9", "url": "https://omabrowser.org/oma/group/A0A5G2RJE9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q14142-1", "protein_name": "Tripartite motif-containing protein 14", "gene_name": "TRIM14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIPRLP", "length": 442 }, "evidence": [ { "id": "A0A5G2RJE9", "url": "https://omabrowser.org/oma/group/A0A5G2RJE9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BVW3-1", "protein_name": "Tripartite motif-containing protein 14", "gene_name": "Trim14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASETTEARAPFQPDGAYGWRCPEHSERPAELFCRRCGRCVCALCPVLGAHRGHPVGLAEEEAVRVQKLIQDCLECLATKKRQHADNIAHLEDAGERLKVYADSSKAWLTQKFTELRLLLDEEEVLAKKFIDKSTQLTLQVYREQAETCGKQIEVMDDFSTRVWGIGQEPNPVQLLQAYIATKTEMGQQMSPSELSHPVPLSFEPVKNFFKEFVEAIGNTLQTPMDTRLKENINCQLSNSSSTKPGALLKTSPSPERALFLKYARTPTLDPDTMHARLRLSPDGLTVRCSLLGRLGPRPAPRFDALRQVLGRDGFAAGRHYWEVDVQEAGVGWWVGAAYPSLRRRGASAAARLGCNRESWCVKRYDLEYWAFHDGQRSRLRPRRDPHRLGVFLDYEAGILAFYDVAGGMSHLHTFHAAFQEPLYPALRLWEGPISIPRLP", "length": 440 }, "evidence": [ { "id": "A0A5G2RJE9", "url": "https://omabrowser.org/oma/group/A0A5G2RJE9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of viral transcription", "id": "GO:0032897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032897", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJE9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 64, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJE9" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 252, "end_pos": 445, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 303 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 73, "end_pos": 75 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RJP8-1", "uniprot_ac": "A0A5G2RJP8", "uniprot_id": "A0A5G2RJP8_PIG", "mass": { "chemical_mass": 34681.0, "monoisotopic_mass": 34681.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A5G2RJP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJP8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJP8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJP8", "locus": {} } ], "crossref": [ { "id": "A0A5G2RJP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RJP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000043590", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000043590", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RJP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLYSLTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKIFPNKQKLKEYSNTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2RJP8-1|A0A5G2RJP8_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RJP8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RJP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJP8/entry#A0A5G2RJP8-1", "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLYSLTDLEFKREIVKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENIFEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHIIIKMAKVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKIFPNKQKLKEYSNTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2RJP8-1|A0A5G2RJP8_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RJP8-1" }, "locus": { "chromosome": "16", "start_pos": 7659030, "end_pos": 7658143, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090427.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090427.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072149.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072149.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJP8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJP8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RJP8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 296, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RJP8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RJP8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RJX5-1", "uniprot_ac": "A0A5G2RJX5", "uniprot_id": "A0A5G2RJX5_PIG", "mass": { "chemical_mass": 47209.0, "monoisotopic_mass": 47209.0 }, "refseq": {}, "gene_names": [ { "name": "NKAP", "type": "recommended", "evidence": [ { "id": "A0A5G2RJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5" } ] } ], "protein_names": [ { "name": "NFKB activating protein", "type": "synonym", "evidence": [ { "id": "A0A5G2RJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJX5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NKAP", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5", "locus": { "chromosome": "X", "start_pos": 98256632, "end_pos": 98276773, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012613", "url": "https://www.ensembl.org/id/ENSSSCG00000012613" } ] } } ], "crossref": [ { "id": "A0A5G2RJX5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RJX5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012613", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012613", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR009269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HGKQWGD", "url": "https://omabrowser.org/oma/group/HGKQWGD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13087", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13087", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13087:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13087:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15692", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15692", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RJX5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUA7", "url": "https://www.uniprot.org/uniprotkb/F1RUA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUA7-1", "url": "https://www.uniprot.org/uniprotkb/F1RUA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPVSGSRSPEWEASGSGGKRRSSSKSPKPCSKSSRSPRGRRSRSHSCSRSGDRNGLSHQSSGPSQGSRNQSYRSRSRSRSRERPSAPRGAPFASASSAYYGGYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKRKKKSGHSKERSKKRRKKKSSKRKHKKYSDDSDSDSDSDTDSSDEDTKRRAKKSKKKEKKKKRRSKKYKKKKSKKSRKDSSDSSSKESQEELLENPWKDRSKPEEPSDLIGPEAPKTLASQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKEDK", "length": 417, "header": "tr|A0A5G2RJX5-1|A0A5G2RJX5_PIG Isoform 1 of NFKB activating protein OS=Sus scrofa OX=9823 GN=NKAP PE=3 SV=2 CANONICAL=A0A5G2RJX5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RJX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5/entry#A0A5G2RJX5-1", "sequence": { "sequence": "MAPVSGSRSPEWEASGSGGKRRSSSKSPKPCSKSSRSPRGRRSRSHSCSRSGDRNGLSHQSSGPSQGSRNQSYRSRSRSRSRERPSAPRGAPFASASSAYYGGYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKRKKKSGHSKERSKKRRKKKSSKRKHKKYSDDSDSDSDSDTDSSDEDTKRRAKKSKKKEKKKKRRSKKYKKKKSKKSRKDSSDSSSKESQEELLENPWKDRSKPEEPSDLIGPEAPKTLASQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKEDK", "length": 417, "header": "tr|A0A5G2RJX5-1|A0A5G2RJX5_PIG Isoform 1 of NFKB activating protein OS=Sus scrofa OX=9823 GN=NKAP PE=3 SV=2 CANONICAL=A0A5G2RJX5-1" }, "locus": { "chromosome": "X", "start_pos": 98276663, "end_pos": 98256661, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085170.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085170.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072270.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072270.2" } ] } }, { "isoform_ac": "F1RUA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5/entry#F1RUA7-1", "sequence": { "sequence": "MAPVSGSRSPEWEASGSGGKRRSSSKSPKPCSKSSRSPRGRRSRSHSCSRSGDRNGLSHQSSGPSQGSRNQSYRSRSRSRSRERPSAPRGAPFASASSAYYGGYSRPYGSDKPWPSLLDKEREESLRQNSDEHTPVEDEEPKKSTTSASTSEEEKKRKKKSGHSKERSKKRRKKKSSKRKHKKYSDDSDSDSDSDTDSSDEDTKRRAKKSKKKEKKKKRRSKKYKKKKSKKSRKDSSDSSSKESQEELLENPWKDRSKPEEPSDLIGPEAPKTLASQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKEDK", "length": 390, "header": "tr|F1RUA7-1|A0A5G2RJX5_PIG Computationally mapped isoform of NFKB activating protein OS=Sus scrofa OX=9823 GN=NKAP PE=3 SV=3 CANONICAL=A0A5G2RJX5-1" }, "locus": { "chromosome": "X", "start_pos": 98276663, "end_pos": 98256661, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013792.6", "url": "https://www.ensembl.org/id/ENSSSCT00000013792.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013411.4", "url": "https://www.ensembl.org/id/ENSSSCP00000013411.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RUA7", "url": "https://www.uniprot.org/uniprotkb/F1RUA7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G5E5D9-1", "protein_name": "NFKB activating protein", "gene_name": "NKAP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPVSGSRSPEWEASSSGGKRRSSSKSPKPSKSSRSPRGRRSRSRSCSRSGDRNGLSHQLSGPSQGSRNQSYRSRSRSRSRERPSAPRGAPFASASSSAYYGGYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTSSASTSEEEKKKKKKSSHSKERSKKRRKKKSSKRKHKKYSDDSDSDSDSDTDSSDEDTKRRAKKAKKKEKKKKHRSKKYKKKKSKKSRKDSSDSSSKESQEEFLENPWKDRSKPEEPSDLIGPEAPKTLASQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKEDK", "length": 417 }, "evidence": [ { "id": "A0A5G2RJX5", "url": "https://omabrowser.org/oma/group/A0A5G2RJX5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4V7C9-1", "protein_name": "NF-kappa-B-activating protein", "gene_name": "Nkap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPVSGSRSPVREASGGKRRSSSRSPKSIKSSRSPRCRRSRSRSCSRFGDRNGLSHSLSGFSQSSRNQSYRSRSRSRSRERPSAQRSAPFASSSSSAYYGGYSRPYGGDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASSSEDDKKKKRKSSRSKERAKKKRKKKSSKRKHKKYSEDSDSDSESDTDSSDEDSKRRAKKAKKKEKKKKRRGKKYKKKKSKKNRKESSDSSSKESQEEFLENPWKDRSKTEEPSDLIGPEAPKTLASQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKDDK", "length": 415 }, "evidence": [ { "id": "A0A5G2RJX5", "url": "https://omabrowser.org/oma/group/A0A5G2RJX5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D0F4-1", "protein_name": "NF-kappa-B-activating protein", "gene_name": "Nkap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPVSGSRSPEREASGAKRRSPSRSPKSIKSSRSPRCRRSRSRSCSRFGDRNGLSHSLSGFSQSSRNQSYRSRSRSRSRERPSAQRSAPFASASSSAYYGGYSRPYGGDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASSSEDDKKKKRKSSHSKDRAKKKRKKKSSKRKHKKYSEDSDSDSESDTDSSDEDSKRRAKKAKKKDKKKKRRGKKYKKKKSKKNRKESSDSSSKESQEEFLENPWKDRSKAEEPSDLIGPEAPKTLASQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKDDK", "length": 415 }, "evidence": [ { "id": "A0A5G2RJX5", "url": "https://omabrowser.org/oma/group/A0A5G2RJX5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJX5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJX5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5" } ], "pmid": "" }, { "name": "positive regulation of alpha-beta T cell differentiation", "id": "GO:0046638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046638", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJX5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJX5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJX5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJX5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RJX5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 417, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RJX5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RJX5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJX5" }, { "id": "PF06047", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06047" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NF-kappa-B-activating protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 310, "end_pos": 407, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RJY9-1", "uniprot_ac": "A0A5G2RJY9", "uniprot_id": "A0A5G2RJY9_PIG", "mass": { "chemical_mass": 53295.0, "monoisotopic_mass": 53295.0 }, "refseq": {}, "gene_names": [ { "name": "ERO1B", "type": "recommended", "evidence": [ { "id": "A0A5G2RJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9" } ] } ], "protein_names": [ { "name": "thiol oxidase", "type": "recommended", "evidence": [ { "id": "A0A5G2RJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9/entry#names_and_taxonomy" } ] }, { "name": "1.8.3.2", "type": "synonym", "evidence": [ { "id": "A0A5G2RJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ERO1B", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9", "locus": { "chromosome": "14", "start_pos": 55122171, "end_pos": 55057059, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010148", "url": "https://www.ensembl.org/id/ENSSSCG00000010148" } ] } } ], "crossref": [ { "id": "A0A5G2RJY9", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RJY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010148", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010148", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CYKDRLH", "url": "https://omabrowser.org/oma/group/CYKDRLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12613", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12613", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12613:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12613:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-264876", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264876", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17357", "url": "https://www.rhea-db.org/rhea/17357", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "59116", "url": "https://www.rhea-db.org/rhea/59116", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RJY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RGY8", "url": "https://www.uniprot.org/uniprotkb/F1RGY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RGY8-1", "url": "https://www.uniprot.org/uniprotkb/F1RGY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGVQRAGAGQGAAAAVQLLVTLSFLPRVVEAQVTGVLDDCLCDIDSIDNFNTFKIYPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGSSNKYLKVANNTKELEDCEQASKLGAINSTLSNQSKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDNGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLKETWGKPSWGPNMKEFKRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVEEDADTKTLLLNIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSPSKGFQLTRQEIVALLNAFGRLSTSIRELQNFKVLLQHSR", "length": 466, "header": "tr|A0A5G2RJY9-1|A0A5G2RJY9_PIG Isoform 1 of thiol oxidase OS=Sus scrofa OX=9823 GN=ERO1B PE=3 SV=2 CANONICAL=A0A5G2RJY9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RJY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9/entry#A0A5G2RJY9-1", "sequence": { "sequence": "MSGVQRAGAGQGAAAAVQLLVTLSFLPRVVEAQVTGVLDDCLCDIDSIDNFNTFKIYPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGSSNKYLKVANNTKELEDCEQASKLGAINSTLSNQSKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDNGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLKETWGKPSWGPNMKEFKRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVEEDADTKTLLLNIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSPSKGFQLTRQEIVALLNAFGRLSTSIRELQNFKVLLQHSR", "length": 466, "header": "tr|A0A5G2RJY9-1|A0A5G2RJY9_PIG Isoform 1 of thiol oxidase OS=Sus scrofa OX=9823 GN=ERO1B PE=3 SV=2 CANONICAL=A0A5G2RJY9-1" }, "locus": { "chromosome": "14", "start_pos": 55119251, "end_pos": 55057287, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083897.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083897.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072295.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072295.2" } ] } }, { "isoform_ac": "F1RGY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9/entry#F1RGY8-1", "sequence": { "sequence": "PWSLSVARSRPLGWSPGRPPFPGPKGPGRPRRREGQHELGVQRAGAGQGAAAAVQLLVTLSFLPRVVEAQVTGVLDDCLCDIDSIDNFNTFKIYPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGSSNKYLKVANNTKELEDCEQASKLGAINSTLSNQSKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDNGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLKETWGKPSWGPNMKEFKRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVEEDADTKTLLLNIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSPSKGFQLTRQEIVALLNAFGRLSTSIRELQNFKVLLQHSRCHCI", "length": 507, "header": "tr|F1RGY8-1|A0A5G2RJY9_PIG Computationally mapped isoform of thiol oxidase OS=Sus scrofa OX=9823 GN=ERO1B PE=3 SV=3 CANONICAL=A0A5G2RJY9-1" }, "locus": { "chromosome": "14", "start_pos": 55121866, "end_pos": 55057178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011111.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011111.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010823.3", "url": "https://www.ensembl.org/id/ENSSSCP00000010823.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RGY8", "url": "https://www.uniprot.org/uniprotkb/F1RGY8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-264876", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264876", "resource": "Reactome", "description": "Insulin processing" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A3H1-1", "protein_name": "thiol oxidase", "gene_name": "Ero1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGFLRAVAGQGAAAAVQLLVTLGFLSSLVKTQVTGVLDDCLCDIDSIDNFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGRSNKYSQAANNTKELDDCEQANKLGAINSTLSNESKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDNGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEETWGKPSWGPNIKEFKRRFDTVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNLEDDADTKTLLLSIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSPSKGFQLTRQEIVALLNAFGSFTLYLEPILPPRDAGQEASFRVLGSWPAICQQYRSTNLGSMLRTH", "length": 493 }, "evidence": [ { "id": "A0A5G2RJY9", "url": "https://omabrowser.org/oma/group/A0A5G2RJY9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0Y127-1", "protein_name": "thiol oxidase", "gene_name": "ERO1B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGGGSGSRSTAAWARWATRLLAALGSVLAAEAQLTGVLDDCLCDIESIDDFNTFKIFPKIQKLQERDYFRYYKVNLKRPCPFWADDGHCSIKDCHVEPCPESKIPVGIKAGSSNKYSKAANNSKELEDCEQANKLGAVNSTLSNQSKEAFIDWARYDDSQDHFCELDDERSPDAQYVDLLLNPERYTGYKGPSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGGDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEETWGKPRWGPNVKEFTRRFDPIETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSVVDLYTGNGHEDAESKALLLEIFRDTKSFHMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQNLPENSPSKGFQLTRQEIVALVNAFGRLSTSIKELQNFKVLLQQTR", "length": 467 }, "evidence": [ { "id": "A0A5G2RJY9", "url": "https://omabrowser.org/oma/group/A0A5G2RJY9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MW08-1", "protein_name": "thiol oxidase", "gene_name": "ERO1B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSPGVRRAGAGQGAAAAVQLLVTLSFLPSVVEAQVTGVLDDCLCDIDSIDNFNTFKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGNSNKYSKVANNTKELEDCEQASKLGAINSTLSNQSKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEETWGKPSWGPNMKEFKRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVQEDADTKTLLLNIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSPSKGFQLTRQEIVALLNAFGRLSTSIRELQNFKVLLQHSRCHCI", "length": 471 }, "evidence": [ { "id": "A0A5G2RJY9", "url": "https://omabrowser.org/oma/group/A0A5G2RJY9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q03103-1", "protein_name": "Endoplasmic oxidoreductin-1", "gene_name": "ERO1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRLRTAIATLCLTAFTSATSNNSYIATDQTQNAFNDTHFCKVDRNDHVSPSCNVTFNELNAINENIRDDLSALLKSDFFKYFRLDLYKQCSFWDANDGLCLNRACSVDVVEDWDTLPEYWQPEILGSFNNDTMKEADDSDDECKFLDQLCQTSKKPVDIEDTINYCDVNDFNGKNAVLIDLTANPERFTGYGGKQAGQIWSTIYQDNCFTIGETGESLAKDAFYRLVSGFHASIGTHLSKEYLNTKTGKWEPNLDLFMARIGNFPDRVTNMYFNYAVVAKALWKIQPYLPEFSFCDLVNKEIKNKMDNVISQLDTKIFNEDLVFANDLSLTLKDEFRSRFKNVTKIMDCVQCDRCRLWGKIQTTGYATALKILFEINDADEFTKQHIVGKLTKYELIALLQTFGRLSESIESVNMFEKMYGKRLNGSENRLSSFFQNNFFNILKEAGKSIRYTIENINSTKEGKKKTNNSQSHVFDDLKMPKAEIVPRPSNGTVNKWKKAWNTEVNNVLEAFRFIYRSYLDLPRNIWELSLMKVYKFWNKFIGVADYVSEETREPISYKLDIQ", "length": 563 }, "evidence": [ { "id": "A0A5G2RJY9", "url": "https://omabrowser.org/oma/group/A0A5G2RJY9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q86YB8-1", "protein_name": "ERO1-like protein beta", "gene_name": "ERO1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQGVRRAGAGQGVAAAVQLLVTLSFLRSVVEAQVTGVLDDCLCDIDSIDNFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGHSNKYLKMANNTKELEDCEQANKLGAINSTLSNQSKEAFIDWARYDDSRDHFCELDDERSPAAQYVDLLLNPERYTGYKGTSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEETWGKPSWGPNIKEFKHRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNAEEDADTKTLLLNIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSPSKGFQLTRQEIVALLNAFGRLSTSIRDLQNFKVLLQHSR", "length": 467 }, "evidence": [ { "id": "A0A5G2RJY9", "url": "https://omabrowser.org/oma/group/A0A5G2RJY9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R2E9-1", "protein_name": "ERO1-like protein beta", "gene_name": "Ero1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPGFRRAVTGQGAAAAVQLLVTLSFLSSLVKTQVTGVLDDCLCDIDSIDKFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGRSNKYSQAANSTKELDDCEQANKLGAINSTLSNESKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEETWGKPSWGPNIKEFRRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVEDDADTKTLLLSIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQNLPENSPSKGFQLTRQEIVALLNAFGRLSTSIRELQNFKALLQHRR", "length": 467 }, "evidence": [ { "id": "A0A5G2RJY9", "url": "https://omabrowser.org/oma/group/A0A5G2RJY9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7S7-1", "protein_name": "Endoplasmic reticulum oxidoreductin-1", "gene_name": "AERO1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGKGAIKEEESEKKRKTWRWPLATLVVVFLAVAVSSRTNSNVGFFFSDRNSCSCSLQKTGKYKGMIEDCCCDYETVDNLNTEVLNPLLQDLVTTPFFRYYKVKLWCDCPFWPDDGMCRLRDCSVCECPENEFPEPFKKPFVPGLPSDDLKCQEGKPQGAVDRTIDNRAFRGWVETKNPWTHDDDTDSGEMSYVNLQLNPERYTGYTGPSARRIWDSIYSENCPKYSSGETCPEKKVLYKLISGLHSSISMHIAADYLLDESRNQWGQNIELMYDRILRHPDRVRNMYFTYLFVLRAVTKATAYLEQAEYDTGNHAEDLKTQSLIKQLLYSPKLQTACPVPFDEAKLWQGQSGPELKQQIQKQFRNISALMDCVGCEKCRLWGKLQVQGLGTALKILFSVGNQDIGDQTLQLQRNEVIALVNLLNRLSESVKMVHDMSPDVERLMEDQIAKVSAKPARLRRIWDLAVSFW", "length": 469 }, "evidence": [ { "id": "A0A5G2RJY9", "url": "https://omabrowser.org/oma/group/A0A5G2RJY9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V3A6-1", "protein_name": "Ero1-like protein", "gene_name": "Ero1L", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTTRTVQRNLWASAAVVLVLLLLWTDTTGGYFAAIDETETSKNCFCELEGSINDCSCDVDTVDHFNNMKIYPRLQSLLVKNFFRFYKVNLRQECPFWPDDSRCAMRFCQVENCEEQAIPQGIKDKGEHKEKAAFKYTREAQVGGSACSDGEDFDSSLGFLDTSISDQAHREFELWAKHDEAEEDFCIVDDHEEGSQYVDLLLNPERYTGYKGESAHRIWKSIYLENCFGGNNETANKFSNYVPHLDLRNVCLEQRAFYRIISGLHSSINIHLCSKYLLSESKDFLDPQGIWGPNVKEFKRRFSPETTSGEGPHWLRNLYFIYLIELRALAKAAPYLRREDYYTGIAEEDDEVKLAINDMLSVIENFQSHFDENALFSNGIASIKFKHDYKEKFRNISRIMSCVGCDKCKLWGKLQTQGLGTALKILYSEKLNLATESGLWDKPHIEADPIFRLSRTEIVALFNAFGRLSNSIYEMENFRCVLR", "length": 483 }, "evidence": [ { "id": "A0A5G2RJY9", "url": "https://omabrowser.org/oma/group/A0A5G2RJY9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9" } ], "pmid": "" }, { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9" } ], "pmid": "" }, { "name": "thiol oxidase activity", "id": "GO:0016972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016972", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding in endoplasmic reticulum", "id": "GO:0034975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034975", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RJY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17357", "name": "", "equation": "2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17357", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17357" } ] }, { "id": "59116", "name": "", "equation": "[protein]-dithiol + O2 = [protein]-disulfide + H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "59116", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/59116" } ] }, { "id": "R-SSC-9817575", "name": "ERO1B oxidizes P4HB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9817575", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9817575" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RJY9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 466, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RJY9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RJY9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 144, "end_pos": 146 }, { "start_pos": 382, "end_pos": 384 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RK81-1", "uniprot_ac": "A0A5G2RK81", "uniprot_id": "A0A5G2RK81_PIG", "mass": { "chemical_mass": 36329.0, "monoisotopic_mass": 36329.0 }, "refseq": { "ac": "XP_013847451", "name": "olfactory receptor 2AJ1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847451" }, "gene_names": [ { "name": "LOC100622735", "type": "recommended", "evidence": [ { "id": "A0A5G2RK81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81" } ] }, { "name": "LOC100622735", "type": "synonym", "evidence": [ { "id": "XP_013847451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847451" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RK81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2AJ1-like", "type": "synonym", "evidence": [ { "id": "XP_013847451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847451" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RK81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RK81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100622735", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81", "locus": {} } ], "crossref": [ { "id": "A0A5G2RK81", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RK81", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100622735", "url": "https://www.ncbi.nlm.nih.gov/gene/100622735", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100622735", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622735", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MMERENY", "url": "https://omabrowser.org/oma/group/MMERENY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RK81", "url": "https://www.orthodb.org/?gene=A0A5G2RK81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013847451", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847451", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RK81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RK81-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPENHTFSSDFILLGLFSSSQKGLIFFSFIVIIFIMTVTENSVMILLIHKESRLHTPMYFLLSHLSFMDILHVSNIVPKMIINFLSGNRTISFAGCGFQIFLSLTLLGGECLLLAAMSYDRYVAICHPLRYPILMNDYVSILMAGGSWLIGTVNSIVHTAYTLHFPFCGSRAVDHFFCEFPAMLVLSCVDTTHYERGVYVSGIIFLLVPFSLIFASYVQILLTVLQMKSSEAWKKSFSTCFFHMIVIIMYYGPFIFTYMKPKKYHIPGQDKFLAIFYTILTPSFNPIIYSIRNKDVLEAMKNMIKSNFLHKNSRENA", "length": 318, "header": "tr|A0A5G2RK81-1|A0A5G2RK81_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100622735 PE=3 SV=1 CANONICAL=A0A5G2RK81-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RK81-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81/entry#A0A5G2RK81-1", "sequence": { "sequence": "MGPENHTFSSDFILLGLFSSSQKGLIFFSFIVIIFIMTVTENSVMILLIHKESRLHTPMYFLLSHLSFMDILHVSNIVPKMIINFLSGNRTISFAGCGFQIFLSLTLLGGECLLLAAMSYDRYVAICHPLRYPILMNDYVSILMAGGSWLIGTVNSIVHTAYTLHFPFCGSRAVDHFFCEFPAMLVLSCVDTTHYERGVYVSGIIFLLVPFSLIFASYVQILLTVLQMKSSEAWKKSFSTCFFHMIVIIMYYGPFIFTYMKPKKYHIPGQDKFLAIFYTILTPSFNPIIYSIRNKDVLEAMKNMIKSNFLHKNSRENA", "length": 318, "header": "tr|A0A5G2RK81-1|A0A5G2RK81_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100622735 PE=3 SV=1 CANONICAL=A0A5G2RK81-1" }, "locus": { "chromosome": "2", "start_pos": 53687742, "end_pos": 53686789, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086688.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086688.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072450.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072450.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RK81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100622735", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622735", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZAI1-1", "protein_name": "Olfactory receptor", "gene_name": "Or2aj4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGAGNYTFSSDFILLGLFSSSKTSLVFFSFTFFIFIMTITENTLMILLIHRDSRLHTPMYFLLSHLSFMDILHISNIVPKMIADFLSGSRTISFAGCGFQIFLSLTLLGGECLLLAAMSYDRYVAICHPLRYPVLMRDNSSGLLAAGSWLVGILNSIVHTALVLHLPFCNSRAIDHFFCEIPAMLKLSCIDTTHYERGVYVSGIVFLLIPFSMISITYVQILLTVFQMQSSGARQKSLSTCLFHMVVVIMYYGPFIFTYMRPRSYHTPGQDKFLAIFYTILTPTLNPIIYSFRNKDVLMAVKNIIQSNFLNKN", "length": 314 }, "evidence": [ { "id": "A0A5G2RK81", "url": "https://omabrowser.org/oma/group/A0A5G2RK81/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G5E8J1-1", "protein_name": "Olfactory receptor", "gene_name": "Or2aj6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMERENYTFNSDFILLGLFSSSKISLTFFSVIFFIFIMTITENALMILLIHRDSRLHTPMYFLLSHLSFMDILHISNIVPKMIADFLSGSRTISFAGCAFQIFLSLTLLGGECLLLAVMSYDRYVAICHPLRYPVLMRDNFSGLLAAGSWLVGILNSIVHTAFVLHFPFCHSRAIDHFFCEVPAMLKLSCIDTTHYERGVYVSGIIFLLIPFSMISISYVQILLTVFQMHSSGARQKSFSTCLFHMVVVIMYYGPFIFTYMRPRSYHTPGQDKFLAIFYTILTPTLNPIIYSFRNKDVLMALKNIVQSNILNKE", "length": 314 }, "evidence": [ { "id": "A0A5G2RK81", "url": "https://omabrowser.org/oma/group/A0A5G2RK81/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RK81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RK81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RK81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RK81", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RK81-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 318, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RK81-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RK81" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RK81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RK81" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RKQ3-1", "uniprot_ac": "A0A5G2RKQ3", "uniprot_id": "A0A5G2RKQ3_PIG", "mass": { "chemical_mass": 34876.0, "monoisotopic_mass": 34876.0 }, "refseq": { "ac": "XP_020937422", "name": "olfactory receptor 7A17-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937422" }, "gene_names": [ { "name": "LOC100522242", "type": "recommended", "evidence": [ { "id": "A0A5G2RKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3" } ] }, { "name": "LOC100522242", "type": "synonym", "evidence": [ { "id": "XP_020937422", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937422" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7A17-like", "type": "synonym", "evidence": [ { "id": "XP_020937422", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937422" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100522242", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3", "locus": {} } ], "crossref": [ { "id": "A0A5G2RKQ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RKQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522242", "url": "https://www.ncbi.nlm.nih.gov/gene/100522242", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511247", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511247", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ssc:100522242", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522242", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QRTEVHI", "url": "https://omabrowser.org/oma/group/QRTEVHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RKQ3", "url": "https://www.orthodb.org/?gene=A0A5G2RKQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020937422", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937422", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAENDTSVSEFYLMGLSKEPALQPLIFGLFLSMYLITVFGNLLIILAVSLDSHLQTPMYFFLSNLSFVDICFTTTTIPKMLQNIWTQNKVITYEGCIIQMYFFILFATLDMFLLTVMAYDRFVAICHPLHYTVIMKPLLCRLLVLASWIMSALNSLFQSIMVLWLSFCTDLEIPHFFCEINQVVQLACSDTSLNDTVMYFAAGVYGGASLTGILYSYFKIVSSIQRISSLRGKYKAFSTCASHLSVVSLFYCTVLGVYLSASATHSSHSSAVASVMYTVITPMLNPFIYSLKNKDIKRALRRITGMAAM", "length": 310, "header": "tr|A0A5G2RKQ3-1|A0A5G2RKQ3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100522242 PE=3 SV=1 CANONICAL=A0A5G2RKQ3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RKQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3/entry#A0A5G2RKQ3-1", "sequence": { "sequence": "MEAENDTSVSEFYLMGLSKEPALQPLIFGLFLSMYLITVFGNLLIILAVSLDSHLQTPMYFFLSNLSFVDICFTTTTIPKMLQNIWTQNKVITYEGCIIQMYFFILFATLDMFLLTVMAYDRFVAICHPLHYTVIMKPLLCRLLVLASWIMSALNSLFQSIMVLWLSFCTDLEIPHFFCEINQVVQLACSDTSLNDTVMYFAAGVYGGASLTGILYSYFKIVSSIQRISSLRGKYKAFSTCASHLSVVSLFYCTVLGVYLSASATHSSHSSAVASVMYTVITPMLNPFIYSLKNKDIKRALRRITGMAAM", "length": 310, "header": "tr|A0A5G2RKQ3-1|A0A5G2RKQ3_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100522242 PE=3 SV=1 CANONICAL=A0A5G2RKQ3-1" }, "locus": { "chromosome": "AEMK02000630.1", "start_pos": 107384, "end_pos": 106455, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090962.1", "url": "https://www.ensembl.org/id/ENSSSCT00000090962.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072742.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072742.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511247", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511247", "resource": "KEGG Pathway" }, { "id": "ssc:100522242", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522242", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RKQ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RKQ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RKQ3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKQ3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RKY6-1", "uniprot_ac": "A0A5G2RKY6", "uniprot_id": "A0A5G2RKY6_PIG", "mass": { "chemical_mass": 66071.0, "monoisotopic_mass": 66071.0 }, "refseq": { "ac": "XP_020949472", "name": "activating signal cointegrator 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949472" }, "gene_names": [ { "name": "TRIP4", "type": "recommended", "evidence": [ { "id": "A0A5G2RKY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ] }, { "name": "TRIP4", "type": "synonym", "evidence": [ { "id": "XP_020949472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949472" } ] } ], "protein_names": [ { "name": "Activating signal cointegrator 1", "type": "recommended", "evidence": [ { "id": "A0A5G2RKY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6/entry#names_and_taxonomy" } ] }, { "name": "Thyroid receptor-interacting protein 4", "type": "synonym", "evidence": [ { "id": "A0A5G2RKY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6/entry#names_and_taxonomy" } ] }, { "name": "activating signal cointegrator 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020949472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949472" } ] } ], "function": [ { "annotation": "Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation. Also involved in androgen receptor transactivation. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. May play a role in the development of neuromuscular junction. May play a role in late myogenic differentiation. Also functions as part of the RQC trigger (RQT) complex that activates the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6#function" }, { "database": "UniProtKB", "id": "ARBA00055901", "url": "https://www.uniprot.org/uniprotkb/ARBA00055901#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TRIP4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6", "locus": { "chromosome": "1", "start_pos": 107588492, "end_pos": 107654639, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004552", "url": "https://www.ensembl.org/id/ENSSSCG00000004552" } ] } } ], "crossref": [ { "id": "A0A5G2RKY6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RKY6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004552", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004552", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06554", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06554", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100153164", "url": "https://www.ncbi.nlm.nih.gov/gene/100153164", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153164", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153164", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RKY6", "url": "https://www.orthodb.org/?gene=A0A5G2RKY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12963:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12963:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23135", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020949472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949472", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0A8", "url": "https://www.uniprot.org/uniprotkb/F1S0A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0A8-1", "url": "https://www.uniprot.org/uniprotkb/F1S0A8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVAGAASQEQLVGWCTQQLRKTFSLDVSEEIIQYILSIESAEEIREYVTDLLQGNEGKKGQFIEELINKWQKNDQELISDALQQSFKKDEILDGQRSGDQLKRSRRKGRNKQEVPAFTEPDMTKEVKTPFDLAKAQENSSSLKKKTKFVSLYTKEGQDKLAVLIPGRHPCDCLGQKHKLINNCLICGRIVCEQEGSGPCLFCGTLVCTREEQDILQRDSNKSQKLLKKLMSGAENSGKLDISTKDLLPHQELRFKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKIEREALQKREEELREFRHASRLSKKITIDFAGRRIVEDENPLAEYHSKLDEAIHAIANGTLNQPLATLDRSSEEPLGLLVNPNLYQSPPQWIDQTGVASQKKAFHSAGSGLEFNSGRHPFRIQDQEFQEGFDGGWCLSMHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKRPSPQEVSELQTTYLVLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKDQYPDMSQESDSPFVFICTNPQEMIVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV", "length": 581, "header": "tr|A0A5G2RKY6-1|A0A5G2RKY6_PIG Isoform 1 of Activating signal cointegrator 1 OS=Sus scrofa OX=9823 GN=TRIP4 PE=4 SV=2 CANONICAL=A0A5G2RKY6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RKY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6/entry#A0A5G2RKY6-1", "sequence": { "sequence": "MAVAGAASQEQLVGWCTQQLRKTFSLDVSEEIIQYILSIESAEEIREYVTDLLQGNEGKKGQFIEELINKWQKNDQELISDALQQSFKKDEILDGQRSGDQLKRSRRKGRNKQEVPAFTEPDMTKEVKTPFDLAKAQENSSSLKKKTKFVSLYTKEGQDKLAVLIPGRHPCDCLGQKHKLINNCLICGRIVCEQEGSGPCLFCGTLVCTREEQDILQRDSNKSQKLLKKLMSGAENSGKLDISTKDLLPHQELRFKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKIEREALQKREEELREFRHASRLSKKITIDFAGRRIVEDENPLAEYHSKLDEAIHAIANGTLNQPLATLDRSSEEPLGLLVNPNLYQSPPQWIDQTGVASQKKAFHSAGSGLEFNSGRHPFRIQDQEFQEGFDGGWCLSMHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKRPSPQEVSELQTTYLVLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKDQYPDMSQESDSPFVFICTNPQEMIVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV", "length": 581, "header": "tr|A0A5G2RKY6-1|A0A5G2RKY6_PIG Isoform 1 of Activating signal cointegrator 1 OS=Sus scrofa OX=9823 GN=TRIP4 PE=4 SV=2 CANONICAL=A0A5G2RKY6-1" }, "locus": { "chromosome": "1", "start_pos": 107654626, "end_pos": 107589015, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078372.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078372.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072888.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072888.2" } ] } }, { "isoform_ac": "F1S0A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6/entry#F1S0A8-1", "sequence": { "sequence": "MAVAGAASQEQLVGWCTQQLRKTFSLDVSEEIIQYILSIESAEEIREYVTDLLQGNEGKKGQFIEELINKWQKNDQELISDALQQSFKKDEILDGQRSGDQLKRSRRKGRNKQEVPAFTEPDMTKEVKTPFDLAKAQENSSSLKKKTKFVSLYTKEGQDKLAVLIPGRHPCDCLGQKHKLINNCLICGRIVCEQEGSGPCLFCGTLVCTREEQDILQRDSNKSQKLLKKLMSGAENSGKLDISTKDLLPHQELRFKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKIEREALQKREEELREFRHASRLSKKITIDFAGRRIVEDENPLAEYHSKLDEAIHAIANGTLNQPLATLDRSSEEPLGLLVNPNLYQSPPQWIDQTGVASQKKAFHSAGSGLEFNSGRHPFRIQDQEFQEGFDGGWCLSMHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKRPSPQEVSELQTTYLVLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKDQGNWIPRSIKEQRRG", "length": 539, "header": "tr|F1S0A8-1|A0A5G2RKY6_PIG Computationally mapped isoform of Activating signal cointegrator 1 OS=Sus scrofa OX=9823 GN=TRIP4 PE=4 SV=4 CANONICAL=A0A5G2RKY6-1" }, "locus": { "chromosome": "1", "start_pos": 107654626, "end_pos": 107589038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005028.4", "url": "https://www.ensembl.org/id/ENSSSCT00000005028.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004908.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004908.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0A8", "url": "https://www.uniprot.org/uniprotkb/F1S0A8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153164", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153164", "resource": "KEGG Pathway" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "estrogen receptor signaling pathway", "id": "GO:0030520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030520", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "ribosome-associated ubiquitin-dependent protein catabolic process", "id": "GO:1990116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990116", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "regulation of myoblast differentiation", "id": "GO:0045661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045661", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "ubiquitin-like protein ligase binding", "id": "GO:0044389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044389", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "histone acetyltransferase binding", "id": "GO:0035035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035035", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" }, { "name": "RQC-trigger complex", "id": "GO:0180022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180022", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKY6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RKY6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 581, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RKY6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RKY6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RKY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKY6" }, { "id": "SM01022", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ASCH", "eco_id": "ECO_0000259", "start_pos": 437, "end_pos": 551, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 358, "end_pos": 360 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RL03-1", "uniprot_ac": "A0A5G2RL03", "uniprot_id": "A0A5G2RL03_PIG", "mass": { "chemical_mass": 17936.0, "monoisotopic_mass": 17936.0 }, "refseq": { "ac": "XP_005659204", "name": "protein phosphatase 1 regulatory subunit 14C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659204" }, "gene_names": [ { "name": "PPP1R14C", "type": "recommended", "evidence": [ { "id": "A0A5G2RL03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03" } ] }, { "name": "PPP1R14C", "type": "synonym", "evidence": [ { "id": "XP_005659204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659204" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 14", "type": "recommended", "evidence": [ { "id": "A0A5G2RL03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1 regulatory subunit 14C", "type": "synonym", "evidence": [ { "id": "XP_005659204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659204" } ] } ], "function": [ { "annotation": "Inhibitor of PPP1CA.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL03", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03#function" }, { "database": "UniProtKB", "id": "RU369059", "url": "https://www.uniprot.org/uniprotkb/RU369059#function" }, { "database": "UniProtKB", "id": "F1S7V6", "url": "https://www.uniprot.org/uniprotkb/F1S7V6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL03", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PPP1R14C", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03", "locus": { "chromosome": "1", "start_pos": 15865220, "end_pos": 15949956, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004094", "url": "https://www.ensembl.org/id/ENSSSCG00000004094" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004094", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004094", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100521302", "url": "https://www.ncbi.nlm.nih.gov/gene/100521302", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521302", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521302", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PARVFFQ", "url": "https://omabrowser.org/oma/group/PARVFFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RL03", "url": "https://www.orthodb.org/?gene=A0A5G2RL03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16188:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16188:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05361", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05361", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005659204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659204", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RL03", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RL03-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S7V6", "url": "https://www.uniprot.org/uniprotkb/F1S7V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S7V6-1", "url": "https://www.uniprot.org/uniprotkb/F1S7V6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVATGSNEAAGGAGGGGARVFFQSPRGGAGGSPGSSSGSGSSREDSAPVATAVATGQVQQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERALKLREALVDCYKPTEEFIKELLSRIRGMRKLSPPQKKTV", "length": 165, "header": "tr|A0A5G2RL03-1|A0A5G2RL03_PIG Isoform 1 of Protein phosphatase 1 regulatory subunit 14 OS=Sus scrofa OX=9823 GN=PPP1R14C PE=1 SV=1 CANONICAL=A0A5G2RL03-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RL03-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03/entry#A0A5G2RL03-1", "sequence": { "sequence": "MSVATGSNEAAGGAGGGGARVFFQSPRGGAGGSPGSSSGSGSSREDSAPVATAVATGQVQQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERALKLREALVDCYKPTEEFIKELLSRIRGMRKLSPPQKKTV", "length": 165, "header": "tr|A0A5G2RL03-1|A0A5G2RL03_PIG Isoform 1 of Protein phosphatase 1 regulatory subunit 14 OS=Sus scrofa OX=9823 GN=PPP1R14C PE=1 SV=1 CANONICAL=A0A5G2RL03-1" }, "locus": { "chromosome": "1", "start_pos": 15949819, "end_pos": 15869373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084792.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084792.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072933.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072933.1" } ] } }, { "isoform_ac": "F1S7V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03/entry#F1S7V6-1", "sequence": { "sequence": "MSVATGSNEAAGGAGGGGARVFFQSPRGGAGGSPGSSSGSGSSREDSAPVATAVATGQVQQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERALKLREFIKELLSRIRGMRKLSPPQKKTV", "length": 154, "header": "tr|F1S7V6-1|F1S7V6_PIG Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 14 OS=Sus scrofa OX=9823 GN=PPP1R14C PE=1 SV=2 CANONICAL=A0A5G2RL03-1" }, "locus": { "chromosome": "1", "start_pos": 15949819, "end_pos": 15869373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004526.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004526.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004424.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004424.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL03", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521302", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521302", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PUM3-1", "protein_name": "Protein phosphatase 1 regulatory inhibitor subunit 14C", "gene_name": "PPP1R14C", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSVATGGSEAAAAAGGGGGGGRVFFQSPRGGGSGREDAVSAAAVQVQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCQEEEMPDVEIDIDDLLDAANEEERALKLQETLVDCYKPTEEFIKELLTRIRGMRKLSPPQKKSI", "length": 149 }, "evidence": [ { "id": "A0A5G2RL03", "url": "https://omabrowser.org/oma/group/A0A5G2RL03/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8R4S0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVVTGGGEAAGGGGGGGARVFFQSPRGGTGGSPGSSSSSGSSREDSAPVTTVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDANSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A5G2RL03", "url": "https://omabrowser.org/oma/group/A0A5G2RL03/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TAE6-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "PPP1R14C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVATGSSETAGGASGGGARVFFQSPRGGAGGSPGSSSGSGSSREDSAPVATAAAAGQVQQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPEVEIDIDDLLDADSDEERASKLQEALVDCYKPTEEFIKELLSRIRGMRKLSPPQKKSV", "length": 165 }, "evidence": [ { "id": "A0A5G2RL03", "url": "https://omabrowser.org/oma/group/A0A5G2RL03/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine phosphatase inhibitor activity", "id": "GO:0004865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004865", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL03", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03" } ], "pmid": "" }, { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL03", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL03", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL03", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RL09-1", "uniprot_ac": "A0A5G2RL09", "uniprot_id": "A0A5G2RL09_PIG", "mass": { "chemical_mass": 34911.0, "monoisotopic_mass": 34911.0 }, "refseq": { "ac": "XP_003124258", "name": "olfactory receptor 140-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124258" }, "gene_names": [ { "name": "LOC100524365", "type": "recommended", "evidence": [ { "id": "A0A5G2RL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09" } ] }, { "name": "LOC100524365", "type": "synonym", "evidence": [ { "id": "XP_003124258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124258" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 140-like", "type": "synonym", "evidence": [ { "id": "XP_003124258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124258" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL09", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL09", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100524365", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09", "locus": {} } ], "crossref": [ { "id": "A0A5G2RL09", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RL09", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000049860", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000049860", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524365", "url": "https://www.ncbi.nlm.nih.gov/gene/100524365", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524365", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524365", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RL09", "url": "https://www.orthodb.org/?gene=A0A5G2RL09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003124258", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124258", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RL09", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RL09-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLPTSPNNVTEFVLLGFTQNPHLQKILFTVFLFIFLVTLLANLFIVIIISLSPTLSTPMYFFLTYLAVIDASFSSVTTPKITIDLLYQRTTISWGGCMTQLFLEHFLGGSETIVLIAMAYDRYVAICKPLHYTTIMRHGLCQLLIGVAWISGILHATVQIHFVLDLPFCGPKVIDHFMCEFFSLLELACTDTYWRGIVISVNTGGMCLLFFFLLIISYMVILNSLKSHGSEGRCKALSTCGSHFTVMVLFFVPCIYIYIRPMATYPMDKLVSLFYGTFTPMLNPIIYTVRNTEVKNAMKCLLKRRVI", "length": 308, "header": "tr|A0A5G2RL09-1|A0A5G2RL09_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524365 PE=3 SV=1 CANONICAL=A0A5G2RL09-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RL09-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09/entry#A0A5G2RL09-1", "sequence": { "sequence": "MDLPTSPNNVTEFVLLGFTQNPHLQKILFTVFLFIFLVTLLANLFIVIIISLSPTLSTPMYFFLTYLAVIDASFSSVTTPKITIDLLYQRTTISWGGCMTQLFLEHFLGGSETIVLIAMAYDRYVAICKPLHYTTIMRHGLCQLLIGVAWISGILHATVQIHFVLDLPFCGPKVIDHFMCEFFSLLELACTDTYWRGIVISVNTGGMCLLFFFLLIISYMVILNSLKSHGSEGRCKALSTCGSHFTVMVLFFVPCIYIYIRPMATYPMDKLVSLFYGTFTPMLNPIIYTVRNTEVKNAMKCLLKRRVI", "length": 308, "header": "tr|A0A5G2RL09-1|A0A5G2RL09_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524365 PE=3 SV=1 CANONICAL=A0A5G2RL09-1" }, "locus": { "chromosome": "AEMK02000261.1", "start_pos": 525503, "end_pos": 524580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088551.1", "url": "https://www.ensembl.org/id/ENSSSCT00000088551.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072943.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072943.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL09", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524365", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524365", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL09", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL09", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL09", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RL09-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 308, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RL09-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RL09" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL09" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 288, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RL63-1", "uniprot_ac": "A0A5G2RL63", "uniprot_id": "A0A5G2RL63_PIG", "mass": { "chemical_mass": 35538.0, "monoisotopic_mass": 35538.0 }, "refseq": { "ac": "XP_003130031", "name": "olfactory receptor 6M1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130031" }, "gene_names": [ { "name": "LOC100513559", "type": "synonym", "evidence": [ { "id": "XP_003130031", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130031" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL63/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6M1-like", "type": "synonym", "evidence": [ { "id": "XP_003130031", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130031" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL63", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL63#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL63", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL63" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL63", "locus": {} } ], "crossref": [ { "id": "A0A5G2RL63", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RL63", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513559", "url": "https://www.ncbi.nlm.nih.gov/gene/100513559", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513559", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513559", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PFCHTEI", "url": "https://omabrowser.org/oma/group/PFCHTEI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RL63", "url": "https://www.orthodb.org/?gene=A0A5G2RL63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003130031", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130031", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RL63", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RL63-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVQNQTTVTEFILTAFPALHKLQVFLFAVLLVTYMLTLTGNGVIISLIWADNRLQTPMYFFLSNLSFLDILFTSSVTPKLLACLLEDRKTISLAGCITQTYFFFFLGTVEFILLVVMSFDRYVAICNPLRYTIIMNSRVCLLLVLGCWVGAFLSVLCPVILLSRLPFCSEEINHFFCDIAPLLQAACINTHFLEMISFLLSSLVLLTSLVLTTVSYTYIISTILRIPSAQGRQKAFSTCASHITVVSIAYGSNIFMYVRPSQSHSLEFDKVTAVLTIMGTPLLNPFIYSLRNEKVKEVLRDAVNKIMSLWHQKP", "length": 315, "header": "tr|A0A5G2RL63-1|A0A5G2RL63_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RL63-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RL63-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL63/entry#A0A5G2RL63-1", "sequence": { "sequence": "MEVQNQTTVTEFILTAFPALHKLQVFLFAVLLVTYMLTLTGNGVIISLIWADNRLQTPMYFFLSNLSFLDILFTSSVTPKLLACLLEDRKTISLAGCITQTYFFFFLGTVEFILLVVMSFDRYVAICNPLRYTIIMNSRVCLLLVLGCWVGAFLSVLCPVILLSRLPFCSEEINHFFCDIAPLLQAACINTHFLEMISFLLSSLVLLTSLVLTTVSYTYIISTILRIPSAQGRQKAFSTCASHITVVSIAYGSNIFMYVRPSQSHSLEFDKVTAVLTIMGTPLLNPFIYSLRNEKVKEVLRDAVNKIMSLWHQKP", "length": 315, "header": "tr|A0A5G2RL63-1|A0A5G2RL63_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RL63-1" }, "locus": { "chromosome": "9", "start_pos": 50652933, "end_pos": 50651989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106217.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106217.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080263.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080263.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL63", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL63" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513559", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513559", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MXJ5-1", "protein_name": "Olfactory receptor", "gene_name": "OR6M2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDVQNQTTVTEFILTAFPALQKLQIFLFVVLLFTYMLTLTGNGVIISLIWADNRLQTPMYFFLSNLSFLDILFTSSVTPKLLSFLLNDRKTISLAGCISQTYFFFFLGTVEFILLVVMSFDRYVAICKPLRYTIIMNSRACLLLVLGCWVGAFLSVLCPVILLSRLPFCHTEINHFFCDIAPLLQVACIDTHFLEMMSFLLSSLILLTSLLITTVSYTYIISTILSIPSAQGRQKAFSTCASHITVVSIAYGSNIFMYVRPSQSHSLQFDKVTAVLTIMVTPLLNPFIYSLRNEKVKEVLRDAVNKIVSLLHRKP", "length": 315 }, "evidence": [ { "id": "A0A5G2RL63", "url": "https://omabrowser.org/oma/group/A0A5G2RL63/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL63", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL63" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL63", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL63" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RL63", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RL63-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 315, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RL63-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RL63" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RL63" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RLG2-1", "uniprot_ac": "A0A5G2RLG2", "uniprot_id": "A0A5G2RLG2_PIG", "mass": { "chemical_mass": 34551.0, "monoisotopic_mass": 34551.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "L1 transposable element RRM domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A5G2RLG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2", "locus": {} } ], "crossref": [ { "id": "A0A5G2RLG2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RLG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000051543", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000051543", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RLG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSQTDLEFKREILKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENISEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHSIIKMANVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKNFPNKQELKEYSNTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2RLG2-1|A0A5G2RLG2_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RLG2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RLG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2/entry#A0A5G2RLG2-1", "sequence": { "sequence": "MKKLRNHPQSNQQENSPKTVNNETDLCSQTDLEFKREILKILKELREDMNSNADTLRKELENIRRSQEKLEHSFAEMQTELGAVKTRMNNAEERISDMEDRIMEITQSGQQTENRIKKLESNIRDLWDNIKRANLRIIGIPEGVEKDKGMENISEEIIAGNFPNLKDTGFKIQEAQRAPNKLNPNRPTPRHSIIKMANVSDKERILKAAREKQNVTYKGTPIRISADFSTETLQARREWQEIFKVLKGKNMQPRILYPARISFKIEGEIKNFPNKQELKEYSNTKPRLKEILKGLL", "length": 296, "header": "tr|A0A5G2RLG2-1|A0A5G2RLG2_PIG Isoform 1 of L1 transposable element RRM domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A5G2RLG2-1" }, "locus": { "chromosome": "9", "start_pos": 80316395, "end_pos": 80315508, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084194.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084194.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073153.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073153.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrotransposition", "id": "GO:0032197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032197", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLG2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RLG2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 296, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RLG2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RLG2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RLG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 227, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RLG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2" }, { "id": "PF17490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element dsRBD-like", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 293, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RLG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLG2" }, { "id": "PF17489", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17489" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element trimerization", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 128, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RLJ3-1", "uniprot_ac": "A0A5G2RLJ3", "uniprot_id": "A0A5G2RLJ3_PIG", "mass": { "chemical_mass": 9056.0, "monoisotopic_mass": 9056.0 }, "refseq": { "ac": "XP_005670015", "name": "serine palmitoyltransferase small subunit B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670015" }, "gene_names": [ { "name": "SPTSSB", "type": "recommended", "evidence": [ { "id": "A0A5G2RLJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3" } ] }, { "name": "SPTSSB", "type": "synonym", "evidence": [ { "id": "XP_005670015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670015" } ] } ], "protein_names": [ { "name": "Serine palmitoyltransferase small subunit B", "type": "recommended", "evidence": [ { "id": "A0A5G2RLJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3/entry#names_and_taxonomy" } ] }, { "name": "Protein ADMP", "type": "synonym", "evidence": [ { "id": "A0A5G2RLJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3/entry#names_and_taxonomy" } ] }, { "name": "Small subunit of serine palmitoyltransferase B", "type": "synonym", "evidence": [ { "id": "A0A5G2RLJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3/entry#names_and_taxonomy" } ] }, { "name": "serine palmitoyltransferase small subunit B", "type": "synonym", "evidence": [ { "id": "XP_005670015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670015" } ] } ], "function": [ { "annotation": "Component of the serine palmitoyltransferase multisubunit enzyme (SPT) that catalyzes the initial and rate-limiting step in sphingolipid biosynthesis by condensing L-serine and activated acyl-CoA (most commonly palmitoyl-CoA) to form long-chain bases. The SPT complex is composed of SPTLC1, SPTLC2 or SPTLC3 and SPTSSA or SPTSSB. Within this complex, the heterodimer consisting of SPTLC1 and SPTLC2/SPTLC3 forms the catalytic core. Within the SPT complex, SPTSSB stimulates the catalytic activity and plays a role in substrate specificity. SPT complexes with this subunit showing a preference for longer acyl-CoAs. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1GIS5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GIS5#function" }, { "database": "UniProtKB", "id": "ARBA00045772", "url": "https://www.uniprot.org/uniprotkb/ARBA00045772#function" }, { "database": "UniProtKB", "id": "A0A5G2RLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SPTSSB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3", "locus": { "chromosome": "13", "start_pos": 101023812, "end_pos": 101059885, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000029080", "url": "https://www.ensembl.org/id/ENSSSCG00000029080" } ] } } ], "crossref": [ { "id": "ENSSSCG00000029080", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000029080", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100623291", "url": "https://www.ncbi.nlm.nih.gov/gene/100623291", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024512", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024512", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623291", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623291", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WEFFSEI", "url": "https://omabrowser.org/oma/group/WEFFSEI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RLJ3", "url": "https://www.orthodb.org/?gene=A0A5G2RLJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28612", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28612", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28612:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28612:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1660661", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660661", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005670015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670015", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1GIS5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GIS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1GIS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GIS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFKGVKDYFSWLYYQYQIISCCAVLEPWEQSMFNTILLTIFAMVVYTAYVFIPIHIRLAWEFFSKICGYQGIVSN", "length": 76, "header": "tr|A0A5G2RLJ3-1|A0A5G2RLJ3_PIG Isoform 1 of Serine palmitoyltransferase small subunit B OS=Sus scrofa OX=9823 GN=SPTSSB PE=3 SV=2 CANONICAL=A0A5G2RLJ3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RLJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3/entry#A0A5G2RLJ3-1", "sequence": { "sequence": "MDFKGVKDYFSWLYYQYQIISCCAVLEPWEQSMFNTILLTIFAMVVYTAYVFIPIHIRLAWEFFSKICGYQGIVSN", "length": 76, "header": "tr|A0A5G2RLJ3-1|A0A5G2RLJ3_PIG Isoform 1 of Serine palmitoyltransferase small subunit B OS=Sus scrofa OX=9823 GN=SPTSSB PE=3 SV=2 CANONICAL=A0A5G2RLJ3-1" }, "locus": { "chromosome": "13", "start_pos": 101031241, "end_pos": 101031014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077700.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077700.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060394.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060394.1" } ] } }, { "isoform_ac": "A0A8D1GIS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3/entry#A0A8D1GIS5-1", "sequence": { "sequence": "MDFKGVKDYFSWLYYQYQIISCCAVLEPWEQSMFNTILLTIFAMVVYTAYVFIPIHIRLAWEFFSKICGYQGL", "length": 73, "header": "tr|A0A8D1GIS5-1|A0A5G2RLJ3_PIG Computationally mapped isoform of Serine palmitoyltransferase small subunit B OS=Sus scrofa OX=9823 GN=SPTSSB PE=3 SV=1 CANONICAL=A0A5G2RLJ3-1" }, "locus": { "chromosome": "13", "start_pos": 101031241, "end_pos": 101024589, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083401.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083401.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065519.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065519.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1GIS5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GIS5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623291", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623291", "resource": "KEGG Pathway" }, { "id": "R-SSC-1660661", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660661", "resource": "Reactome", "description": "Sphingolipid de novo biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IL37-1", "protein_name": "Serine palmitoyltransferase small subunit B", "gene_name": "Sptssb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLKSVKEYFAWLYYQYQIISCCAVLEPWEQSMFNTILLTIVAMVVYTAYVFIPIHIRLAWEFFSKICGYHSSISN", "length": 76 }, "evidence": [ { "id": "A0A5G2RLJ3", "url": "https://omabrowser.org/oma/group/A0A5G2RLJ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A1D5PLF8-1", "protein_name": "Serine palmitoyltransferase small subunit B", "gene_name": "SPTSSB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDIKRVKDYIYWLYYQYLLITCSYALEPWEQSMFHTIMVTVFAMVVYTAYVFVPIHVRLAFEFFSQIFGVQPDSTVSVVN", "length": 80 }, "evidence": [ { "id": "A0A5G2RLJ3", "url": "https://omabrowser.org/oma/group/A0A5G2RLJ3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q0IIK4-1", "protein_name": "Serine palmitoyltransferase small subunit B", "gene_name": "SPTSSB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDFKRVKDYLSWLYYQYQIISCCAVLEPWEQSMFNTIILTIFAMVVYTAYVFIPIHIRLAWEFFSKMCGYHSTISN", "length": 76 }, "evidence": [ { "id": "A0A5G2RLJ3", "url": "https://omabrowser.org/oma/group/A0A5G2RLJ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8NFR3-1", "protein_name": "Serine palmitoyltransferase small subunit B", "gene_name": "SPTSSB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLRRVKEYFSWLYYQYQIISCCAVLEPWERSMFNTILLTIIAMVVYTAYVFIPIHIRLAWEFFSKICGYHSTISN", "length": 76 }, "evidence": [ { "id": "A0A5G2RLJ3", "url": "https://omabrowser.org/oma/group/A0A5G2RLJ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q925E8-1", "protein_name": "Serine palmitoyltransferase small subunit B", "gene_name": "Sptssb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFKRVKEYFAWLYYQYQIITCCAVMEPWEQSMLNTIILTIVAMVVYTAYVFIPIHIRLAWEFFSKICGYDSSISN", "length": 76 }, "evidence": [ { "id": "A0A5G2RLJ3", "url": "https://omabrowser.org/oma/group/A0A5G2RLJ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine C-palmitoyltransferase activity", "id": "GO:0004758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004758", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "serine palmitoyltransferase complex", "id": "GO:0017059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017059", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3" } ], "pmid": "" }, { "name": "sphingosine biosynthetic process", "id": "GO:0046512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046512", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3" } ], "pmid": "" }, { "name": "endoplasmic reticulum organization", "id": "GO:0007029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007029", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3" } ], "pmid": "" }, { "name": "sphingolipid metabolic process", "id": "GO:0006665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006665", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RLR3-1", "uniprot_ac": "A0A5G2RLR3", "uniprot_id": "A0A5G2RLR3_PIG", "mass": { "chemical_mass": 73858.0, "monoisotopic_mass": 73858.0 }, "refseq": {}, "gene_names": [ { "name": "MAP9", "type": "recommended", "evidence": [ { "id": "A0A5G2RLR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3" } ] } ], "protein_names": [ { "name": "Microtubule associated protein 9", "type": "synonym", "evidence": [ { "id": "A0A5G2RLR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MAP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3", "locus": { "chromosome": "8", "start_pos": 42681309, "end_pos": 42733864, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008852", "url": "https://www.ensembl.org/id/ENSSSCG00000008852" } ] } } ], "crossref": [ { "id": "A0A5G2RLR3", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RLR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008852", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008852", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR026106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14739", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14739", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14739:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14739:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2RLR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWD3", "url": "https://www.uniprot.org/uniprotkb/F1RWD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWD3-1", "url": "https://www.uniprot.org/uniprotkb/F1RWD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDEVFSTTLAYTKSPKVTKRTTFQDELIKAITARSARQRSYEYSDDFDSDEIGDFSDTSVDEYSVKKKINDFHIPDDEEKNSPKLSFLKTKKSNNDVRKVEPRVSIKNDKDMEPSGDGEMNVKLLSESQNKQQEIDNEKIKMESKPRIRPIKDTSSGNNNSLEADNHFEPSPRPRSMLKKHNHREGKDGQGEDKETALHEELEVLSAPPYLSRPNGRQSEAENNAVSENVDTEDPCLPSLSSSSLKESLGDSFSPGSGEKQKEECAENHNPLKSNENEENSFLIDVVTIALEKPKETQVSTDDLEEEKQKAELIMNDDLTVDDPPLLQAQSILCTESAKKIIQDRNMKNKKSTNKRVSSASGRLMTSEFLKKSSSLRKTPSTAPTSHYLGTLRVLDQKPSQKQNTEPGRADNIRAAVYQEWLEKKNVYLHEMNRIKRIESENLRIQNEQKRATKREEALASFEAWKAMKEKEAKKVAAKKRLEEKNKKKTEEENAVKKGEALQAFEKWKEKKMEYLKEKNKKEKEYERAKKQKEEETVAEKRKDNLNALEKWNEKKEAFFKEKEKEKRNEKRKEELKEAEKKDKDKQALDEYEKWLEKKERQERIERKQKKQHSFLENEVLPPWSPPSKTVFSKVF", "length": 637, "header": "tr|A0A5G2RLR3-1|A0A5G2RLR3_PIG Isoform 1 of Microtubule associated protein 9 OS=Sus scrofa OX=9823 GN=MAP9 PE=4 SV=2 CANONICAL=A0A5G2RLR3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RLR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3/entry#A0A5G2RLR3-1", "sequence": { "sequence": "MSDEVFSTTLAYTKSPKVTKRTTFQDELIKAITARSARQRSYEYSDDFDSDEIGDFSDTSVDEYSVKKKINDFHIPDDEEKNSPKLSFLKTKKSNNDVRKVEPRVSIKNDKDMEPSGDGEMNVKLLSESQNKQQEIDNEKIKMESKPRIRPIKDTSSGNNNSLEADNHFEPSPRPRSMLKKHNHREGKDGQGEDKETALHEELEVLSAPPYLSRPNGRQSEAENNAVSENVDTEDPCLPSLSSSSLKESLGDSFSPGSGEKQKEECAENHNPLKSNENEENSFLIDVVTIALEKPKETQVSTDDLEEEKQKAELIMNDDLTVDDPPLLQAQSILCTESAKKIIQDRNMKNKKSTNKRVSSASGRLMTSEFLKKSSSLRKTPSTAPTSHYLGTLRVLDQKPSQKQNTEPGRADNIRAAVYQEWLEKKNVYLHEMNRIKRIESENLRIQNEQKRATKREEALASFEAWKAMKEKEAKKVAAKKRLEEKNKKKTEEENAVKKGEALQAFEKWKEKKMEYLKEKNKKEKEYERAKKQKEEETVAEKRKDNLNALEKWNEKKEAFFKEKEKEKRNEKRKEELKEAEKKDKDKQALDEYEKWLEKKERQERIERKQKKQHSFLENEVLPPWSPPSKTVFSKVF", "length": 637, "header": "tr|A0A5G2RLR3-1|A0A5G2RLR3_PIG Isoform 1 of Microtubule associated protein 9 OS=Sus scrofa OX=9823 GN=MAP9 PE=4 SV=2 CANONICAL=A0A5G2RLR3-1" }, "locus": { "chromosome": "8", "start_pos": 42732996, "end_pos": 42681978, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090922.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090922.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073334.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073334.2" } ] } }, { "isoform_ac": "F1RWD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3/entry#F1RWD3-1", "sequence": { "sequence": "MSDEVFSTTLAYTKSPKVTKRTTFQDELIKAITARSARQRSYEYSDDFDSDEIGDFSDTSVDEYSVKKKINDFHIPDDEEKNSPKLSFLKTKKSNNDVRKVEPRVSIKNDKDMEPSGDGEMNVKLLSESQNKQQEIDNEKIKMESKPRIRPIKDTSSGNNNSLEADNHFEPSPRPRSMLKKHNHREGKDGQGEDKETALHEELEVLSAPPYLSRPNGRQSEAENNAVSENVDTEVSTTLLCGLRDVSIGDPNTEECAENHNPLKSNENEENSFLIDVVTIALEKPKETQVSTDDLEEEKQKAELIMNDDLTVDDPPLLQAQSILCTESAKKIIQDRNMKNKKSTNKRVSSASGRLMTSEFLKKSSSLRKTPSTAPTSHYLGTLRVLDQKPSQKQNTEPGRADNIRAAVYQEWLEKKNVYLHEMNRIKRIESENLRIQNEQKRATKREEALASFEAWKAMKEKEAKKVAAKKRLEEKNKKKTEEENAVKKGEALQAFEKWKEKKMEYLKEKNKKEKEYERAKKQKEEETVAEKRKDNLNALEKWNEKKEAFFKEKEKEKRNEKRKEELKEAEKKDKDKQALDEYEKWLEKKERQERIERKQKKQHSFLENEVLPPWSPPSKTVFSKVF", "length": 627, "header": "tr|F1RWD3-1|A0A5G2RLR3_PIG Computationally mapped isoform of Microtubule associated protein 9 OS=Sus scrofa OX=9823 GN=MAP9 PE=4 SV=4 CANONICAL=A0A5G2RLR3-1" }, "locus": { "chromosome": "8", "start_pos": 42732996, "end_pos": 42681978, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009691.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009691.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009442.5", "url": "https://www.ensembl.org/id/ENSSSCP00000009442.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWD3", "url": "https://www.uniprot.org/uniprotkb/F1RWD3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of mitotic centrosome separation", "id": "GO:0046602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046602", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3" } ], "pmid": "" }, { "name": "regulation of mitotic spindle organization", "id": "GO:0060236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060236", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3" } ], "pmid": "" }, { "name": "regulation of mitotic cytokinesis", "id": "GO:1902412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902412", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "astral microtubule", "id": "GO:0000235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000235", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RLR3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 637, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RLR3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RLR3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RLT5-1", "uniprot_ac": "A0A5G2RLT5", "uniprot_id": "A0A5G2RLT5_PIG", "mass": { "chemical_mass": 127858.0, "monoisotopic_mass": 127858.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A5G2RLT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLT5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5", "locus": {} } ], "crossref": [ { "id": "A0A5G2RLT5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RLT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000049831", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000049831", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03715", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03715", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33064:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33064:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00077", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00077", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09337", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09337", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RLT5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGATGQQQYPWTTRRTVDLGVGRVTHSFLVIPECPAPLLGRDLLTKMGAQISFEQGKPEVSANNKPITVLTLQLDDEYRLYSPLVKPDQNIQFWLEQFPQAWAETAGMDLAKQVPPQVIQLKASAAPVSVRQYPLSKEAREGIRPHVQRLIQQGILVPVQSPWNTPLLPVRKPGTNDYRPVQDLREVNKRVQDIHPTVPNPYNLLCALPPQRSWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPGAGRTGQLTWTRLPQGFKNSPTIFDEALHRDLANFRIQHPQVTLLQYVDDLLLAGATKQDCLEGTKALLLELSDLGYRASAKKAQICRREVTYLGYSLRGGQRWLTEARKRTVVQIPAPTTAKQVREFLGTAGFCRLWIPGFATLAAPLYPLTKEKGEFSWAPEHQKAFDAIKKALLSAPALALPDVTKPFTLYVDEHKGVARGVLTQTLGPWRRPVAYLSKKLDPVASGWPVCLKAIAAVAILVKDADKLTLGQNITVIAPHALENIVRQPPDRWMTNARMTHYQSLLLTERVTFAPPAALNPATLLPEETDEPVTHDCHQLLIEETGVRKDLTDIPLTGEVLTWFTDGSSYVVEGKRMAGAAVVDGTRTIWASSLPEGTSAQKAELMALTQALRLAEGKSINIYTDSRYAFATAHVHGAIYKQRGLLTSAGREIKNKEEILSLLEALHLPKRLAIIHCPGHQKAKDPISRGNQMADRVAKQAAQGVNLLPMIETPKAPEPGRQYTLEDWQEIKKIDQFSETPEGTCYTSDGKEILPHKEGLEYVQQIHRLTHLGTKHLQQLVRTSPYHVLRLPGVADSVVKHCVPCQLVNANPSRIPPGKRLRGSHPGAHWEVDFTEVKPAKYGNKYLLVFVDTFSGWVEAYPTKKETSTVVAKKILEEIFPRFRIPKVIGSDNGPAFVAQVSQGLAKILGIDWKLHCAYRPQSSGQVERMNRTIKETLTKLTTETGINDWIALLPFVLFRVRNTPGQFGLTPYELLYGGPPPLAEIAFAHSADVLLSQPLFSRLKALEWVRQRAWKQLREAYSGGDLQVPHRFQVGDSVYVRRHRAGNLETRWKGPYLVLLTTPTAVKVEGIPTWIHASHVKPAPPPDSGWKAEKTENPLKLRLHHVVPYSVNNSSS", "length": 1144, "header": "tr|A0A5G2RLT5-1|A0A5G2RLT5_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RLT5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RLT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5/entry#A0A5G2RLT5-1", "sequence": { "sequence": "MGATGQQQYPWTTRRTVDLGVGRVTHSFLVIPECPAPLLGRDLLTKMGAQISFEQGKPEVSANNKPITVLTLQLDDEYRLYSPLVKPDQNIQFWLEQFPQAWAETAGMDLAKQVPPQVIQLKASAAPVSVRQYPLSKEAREGIRPHVQRLIQQGILVPVQSPWNTPLLPVRKPGTNDYRPVQDLREVNKRVQDIHPTVPNPYNLLCALPPQRSWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPGAGRTGQLTWTRLPQGFKNSPTIFDEALHRDLANFRIQHPQVTLLQYVDDLLLAGATKQDCLEGTKALLLELSDLGYRASAKKAQICRREVTYLGYSLRGGQRWLTEARKRTVVQIPAPTTAKQVREFLGTAGFCRLWIPGFATLAAPLYPLTKEKGEFSWAPEHQKAFDAIKKALLSAPALALPDVTKPFTLYVDEHKGVARGVLTQTLGPWRRPVAYLSKKLDPVASGWPVCLKAIAAVAILVKDADKLTLGQNITVIAPHALENIVRQPPDRWMTNARMTHYQSLLLTERVTFAPPAALNPATLLPEETDEPVTHDCHQLLIEETGVRKDLTDIPLTGEVLTWFTDGSSYVVEGKRMAGAAVVDGTRTIWASSLPEGTSAQKAELMALTQALRLAEGKSINIYTDSRYAFATAHVHGAIYKQRGLLTSAGREIKNKEEILSLLEALHLPKRLAIIHCPGHQKAKDPISRGNQMADRVAKQAAQGVNLLPMIETPKAPEPGRQYTLEDWQEIKKIDQFSETPEGTCYTSDGKEILPHKEGLEYVQQIHRLTHLGTKHLQQLVRTSPYHVLRLPGVADSVVKHCVPCQLVNANPSRIPPGKRLRGSHPGAHWEVDFTEVKPAKYGNKYLLVFVDTFSGWVEAYPTKKETSTVVAKKILEEIFPRFRIPKVIGSDNGPAFVAQVSQGLAKILGIDWKLHCAYRPQSSGQVERMNRTIKETLTKLTTETGINDWIALLPFVLFRVRNTPGQFGLTPYELLYGGPPPLAEIAFAHSADVLLSQPLFSRLKALEWVRQRAWKQLREAYSGGDLQVPHRFQVGDSVYVRRHRAGNLETRWKGPYLVLLTTPTAVKVEGIPTWIHASHVKPAPPPDSGWKAEKTENPLKLRLHHVVPYSVNNSSS", "length": 1144, "header": "tr|A0A5G2RLT5-1|A0A5G2RLT5_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A5G2RLT5-1" }, "locus": { "chromosome": "5", "start_pos": 92191176, "end_pos": 92187745, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067148.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067148.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073374.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073374.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLT5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLT5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLT5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLT5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLT5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLT5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLT5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" } ], "pmid": "" }, { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLT5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1140, "end_pos": 1142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1141, "end_pos": 1143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 958, "end_pos": 960, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RLT5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1144, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RLT5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RLT5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RLT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 849, "end_pos": 1007, "start_aa": "Arg", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RLT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" }, { "id": "PS50175", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50175" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase A2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 43, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RLT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 584, "end_pos": 730, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RLT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLT5" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 151, "end_pos": 342, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1140, "end_pos": 1142 }, { "start_pos": 1141, "end_pos": 1143 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 958, "end_pos": 960 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RLY0-1", "uniprot_ac": "A0A5G2RLY0", "uniprot_id": "A0A5G2RLY0_PIG", "mass": { "chemical_mass": 41681.0, "monoisotopic_mass": 41681.0 }, "refseq": {}, "gene_names": [ { "name": "ZDHHC18", "type": "recommended", "evidence": [ { "id": "A0A5G2RLY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "A0A5G2RLY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "A0A5G2RLY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZDHHC18", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0", "locus": { "chromosome": "6", "start_pos": 84182305, "end_pos": 84153838, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003561", "url": "https://www.ensembl.org/id/ENSSSCG00000003561" } ] } } ], "crossref": [ { "id": "A0A5G2RLY0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RLY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003561", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003561", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22883", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22883", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22883:SF257", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22883:SF257", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RLY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKDCEYQQISPGAAPPPASPGARRPGPAAPPGPGPGPPPPAAAAPRWSGSGSGSGSGSIGRRPRRKWEVFPGRNRFYCGGRLMLAGHGGVFALTLLLILTTTVLFFVFDCPFLARQLTLAIPIIAAILFFFVMSCLLQTSFTDPGILPRATVCEAAALEKQIDNTGSSTYRPPPRTREVMINGQVVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACVVTHLTLRSQGSNFLSTLKETPASVLELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWSNKRGGEASVNPYSHKSVITNCCAVLCGPLPPSLIDRRGFVQSDTVLPSPIRSDEPACGTKPDASMVGGHP", "length": 385, "header": "tr|A0A5G2RLY0-1|A0A5G2RLY0_PIG Isoform 1 of Palmitoyltransferase OS=Sus scrofa OX=9823 GN=ZDHHC18 PE=3 SV=1 CANONICAL=A0A5G2RLY0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RLY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0/entry#A0A5G2RLY0-1", "sequence": { "sequence": "MKDCEYQQISPGAAPPPASPGARRPGPAAPPGPGPGPPPPAAAAPRWSGSGSGSGSGSIGRRPRRKWEVFPGRNRFYCGGRLMLAGHGGVFALTLLLILTTTVLFFVFDCPFLARQLTLAIPIIAAILFFFVMSCLLQTSFTDPGILPRATVCEAAALEKQIDNTGSSTYRPPPRTREVMINGQVVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACVVTHLTLRSQGSNFLSTLKETPASVLELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWSNKRGGEASVNPYSHKSVITNCCAVLCGPLPPSLIDRRGFVQSDTVLPSPIRSDEPACGTKPDASMVGGHP", "length": 385, "header": "tr|A0A5G2RLY0-1|A0A5G2RLY0_PIG Isoform 1 of Palmitoyltransferase OS=Sus scrofa OX=9823 GN=ZDHHC18 PE=3 SV=1 CANONICAL=A0A5G2RLY0-1" }, "locus": { "chromosome": "6", "start_pos": 84180543, "end_pos": 84153947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070339.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070339.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073444.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073444.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0" } ], "pmid": "" }, { "name": "negative regulation of innate immune response", "id": "GO:0045824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045824", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0" } ], "pmid": "" }, { "name": "negative regulation of cGAS/STING signaling pathway", "id": "GO:0160049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160049", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLY0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RLY0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 385, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RLY0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RLY0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RLY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLY0" }, { "id": "PF01529", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Palmitoyltransferase DHHC", "eco_id": "ECO_0000259", "start_pos": 187, "end_pos": 311, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 303, "end_pos": 305 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RM95-1", "uniprot_ac": "A0A5G2RM95", "uniprot_id": "A0A5G2RM95_PIG", "mass": { "chemical_mass": 40277.0, "monoisotopic_mass": 40277.0 }, "refseq": { "ac": "XP_005658832", "name": "V-set and immunoglobulin domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005658832" }, "gene_names": [ { "name": "VSIG1", "type": "recommended", "evidence": [ { "id": "A0A5G2RM95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM95" } ] }, { "name": "VSIG1", "type": "synonym", "evidence": [ { "id": "XP_005658832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005658832" } ] } ], "protein_names": [ { "name": "V-set and immunoglobulin domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A5G2RM95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM95/entry#names_and_taxonomy" } ] }, { "name": "V-set and immunoglobulin domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005658832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005658832" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RM95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM95" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "VSIG1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM95", "locus": { "chromosome": "X", "start_pos": 88534961, "end_pos": 88500715, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000059089", "url": "https://www.ensembl.org/id/ENSSSCG00000059089" } ] } } ], "crossref": [ { "id": "A0A5G2RM95", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RM95", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012566", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012566", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100626662", "url": "https://www.ncbi.nlm.nih.gov/gene/100626662", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626662", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626662", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RM95", "url": "https://www.orthodb.org/?gene=A0A5G2RM95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44974", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44974", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44974:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44974:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005658832", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005658832", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RM95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RM95-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVFTFWKVFLILHCLAGQVSGVQVTIPDSFVNVTVGSDVTLICTYTTTVASLDKLSIQWTFFHKKELQPVSIYYSEGGQTAVNGQFKDRIVGSNAPGNASITISNMQPADSGIYICDVNNPPDFSGNNQGTLNVNVLVKPSKPFCSIQGIPETGHPVSLTCLSVLGTPSPVYYWHKVEGRDIIPVKENFNPATGILFIGNLTNFEQGYYQCTAMNILGNSSCEIDLTSSHPEVGIIIGALVGTLVGAAIITSVVCFARSKAKGKERKRNSKTTAELEPMTKINQSTECEAVPNEDVIHLEETLPPSIHEAEPDTTLGPDHEPIPEPEPAAGPKLVPVPEVEIQLEPEPKPQQEPEPAIVVEPLGDEEKGAMKL", "length": 373, "header": "tr|A0A5G2RM95-1|A0A5G2RM95_PIG Isoform 1 of V-set and immunoglobulin domain-containing protein 1 OS=Sus scrofa OX=9823 GN=VSIG1 PE=4 SV=1 CANONICAL=A0A5G2RM95-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RM95-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM95/entry#A0A5G2RM95-1", "sequence": { "sequence": "MVFTFWKVFLILHCLAGQVSGVQVTIPDSFVNVTVGSDVTLICTYTTTVASLDKLSIQWTFFHKKELQPVSIYYSEGGQTAVNGQFKDRIVGSNAPGNASITISNMQPADSGIYICDVNNPPDFSGNNQGTLNVNVLVKPSKPFCSIQGIPETGHPVSLTCLSVLGTPSPVYYWHKVEGRDIIPVKENFNPATGILFIGNLTNFEQGYYQCTAMNILGNSSCEIDLTSSHPEVGIIIGALVGTLVGAAIITSVVCFARSKAKGKERKRNSKTTAELEPMTKINQSTECEAVPNEDVIHLEETLPPSIHEAEPDTTLGPDHEPIPEPEPAAGPKLVPVPEVEIQLEPEPKPQQEPEPAIVVEPLGDEEKGAMKL", "length": 373, "header": "tr|A0A5G2RM95-1|A0A5G2RM95_PIG Isoform 1 of V-set and immunoglobulin domain-containing protein 1 OS=Sus scrofa OX=9823 GN=VSIG1 PE=4 SV=1 CANONICAL=A0A5G2RM95-1" }, "locus": { "chromosome": "X", "start_pos": 88533919, "end_pos": 88500914, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069480.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069480.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073659.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073659.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RM95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM95" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626662", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626662", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RM95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM95" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "maintenance of gastrointestinal epithelium", "id": "GO:0030277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030277", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RM95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM95" } ], "pmid": "" }, { "name": "epithelial cell morphogenesis", "id": "GO:0003382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003382", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RM95", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RM95-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 373, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RM95-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RM95" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RM95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM95" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 133, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 34 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RN21-1", "uniprot_ac": "A0A5G2RN21", "uniprot_id": "A0A5G2RN21_PIG", "mass": { "chemical_mass": 113274.0, "monoisotopic_mass": 113274.0 }, "refseq": {}, "gene_names": [ { "name": "NLRP12", "type": "recommended", "evidence": [ { "id": "A0A5G2RN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 12", "type": "recommended", "evidence": [ { "id": "A0A5G2RN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21/entry#names_and_taxonomy" } ] }, { "name": "Monarch-1", "type": "synonym", "evidence": [ { "id": "A0A5G2RN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21/entry#names_and_taxonomy" } ] }, { "name": "PYRIN-containing APAF1-like protein 7", "type": "synonym", "evidence": [ { "id": "A0A5G2RN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays an essential role as an potent mitigator of inflammation. Primarily expressed in dendritic cells and macrophages, inhibits both canonical and non-canonical NF-kappa-B and ERK activation pathways. Functions as a negative regulator of NOD2 by targeting it to degradation via the proteasome pathway. In turn, promotes bacterial tolerance. Also inhibits the RIGI-mediated immune signaling against RNA viruses by reducing the E3 ubiquitin ligase TRIM25-mediated 'Lys-63'-linked RIGI activation but enhancing the E3 ubiquitin ligase RNF125-mediated 'Lys-48'-linked RIGI degradation. Also acts as a negative regulator of inflammatory response to mitigate obesity and obesity-associated diseases in adipose tissue.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21#function" }, { "database": "UniProtKB", "id": "ARBA00056883", "url": "https://www.uniprot.org/uniprotkb/ARBA00056883#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NLRP12", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21", "locus": { "chromosome": "6", "start_pos": 56425101, "end_pos": 56402665, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003251", "url": "https://www.ensembl.org/id/ENSSSCG00000003251" } ] } } ], "crossref": [ { "id": "A0A5G2RN21", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RN21", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003251", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003251", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08320", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08320", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050637", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050637", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45690:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45690:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RN21-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPTPLRNGLCRLCAYLEELEAVELKKFKLYLGMATEMGKHKIPWGRMEPAGPLEMAQLLAAHCGIREAWLLTLSIFEQINRKDLWERGQREDLVRETPPGDLFSPGNQSACSLEDFPATLRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPLRAQQKLLDTGQGHARTVGHPAGLIQMETLFEPDEERPEPPRIVVLQGAAGMGKSMLAHKVMLDWADGKLFQDRFDYVFYINCREMNQSTVERSAQDLISSCWPEPSVPLHELVRAPERLLFIIDGFDELKPSFHDPQGPWCLCWEKKRPTEVLLRSLIRKKLMPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEFFYKYFPSEEQASHVFSFVRDNEPLFTLCFIPMVCWVVCTCLKQQLEGGGLLRHTSRTTTAVYLLYLLSLMQPKPGTPTLQPPPNQRGLCSLAADGLWHQKILFEEQDLRKHGLEVADVSSFLNMNIFQKDINCEKFYSFIHLSFQEFFAAMYYILDGGDSRSGPEQNITRLLSEYAFSERSFLALTVRFLFGLLNEETRCSLEKMLGWKVSPHAKMELLEWIRSKAQSEGSTLKQGSLEFFSCLYELQEEEFIQQALSHFQVVVVNSIATKMEHMVSSFCAKNCRNAAVLQLYGAAYNADGEDGVRWPQMPLAQSPERNLLPDAYSEQLAAALSTSPNLVELVLYSNALGSRGVKLLCQGLGHPNCNLQNLRLKRCQISSSACQDLALALIANKHLVRMDLSGNSLGLPGVKLLCKGLRHPKCRLQMVQLRKCQLEAGACQEIASVLSSSRHLEELDLTGNALEDSGLRLLCQGLRHPVCRLRILWLKICQLSAAACEDLAATLSGNQSLMELDLSLNELGDPGVLLLCEGLRHPQCKLQTLRLDSCGLTAKACEDLSSMLGVNQTLTELYLTNNVLGNTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHRSLAALRVTKPYLDIGC", "length": 1001, "header": "tr|A0A5G2RN21-1|A0A5G2RN21_PIG Isoform 1 of NACHT, LRR and PYD domains-containing protein 12 OS=Sus scrofa OX=9823 GN=NLRP12 PE=3 SV=1 CANONICAL=A0A5G2RN21-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RN21-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21/entry#A0A5G2RN21-1", "sequence": { "sequence": "MSPTPLRNGLCRLCAYLEELEAVELKKFKLYLGMATEMGKHKIPWGRMEPAGPLEMAQLLAAHCGIREAWLLTLSIFEQINRKDLWERGQREDLVRETPPGDLFSPGNQSACSLEDFPATLRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPLRAQQKLLDTGQGHARTVGHPAGLIQMETLFEPDEERPEPPRIVVLQGAAGMGKSMLAHKVMLDWADGKLFQDRFDYVFYINCREMNQSTVERSAQDLISSCWPEPSVPLHELVRAPERLLFIIDGFDELKPSFHDPQGPWCLCWEKKRPTEVLLRSLIRKKLMPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEFFYKYFPSEEQASHVFSFVRDNEPLFTLCFIPMVCWVVCTCLKQQLEGGGLLRHTSRTTTAVYLLYLLSLMQPKPGTPTLQPPPNQRGLCSLAADGLWHQKILFEEQDLRKHGLEVADVSSFLNMNIFQKDINCEKFYSFIHLSFQEFFAAMYYILDGGDSRSGPEQNITRLLSEYAFSERSFLALTVRFLFGLLNEETRCSLEKMLGWKVSPHAKMELLEWIRSKAQSEGSTLKQGSLEFFSCLYELQEEEFIQQALSHFQVVVVNSIATKMEHMVSSFCAKNCRNAAVLQLYGAAYNADGEDGVRWPQMPLAQSPERNLLPDAYSEQLAAALSTSPNLVELVLYSNALGSRGVKLLCQGLGHPNCNLQNLRLKRCQISSSACQDLALALIANKHLVRMDLSGNSLGLPGVKLLCKGLRHPKCRLQMVQLRKCQLEAGACQEIASVLSSSRHLEELDLTGNALEDSGLRLLCQGLRHPVCRLRILWLKICQLSAAACEDLAATLSGNQSLMELDLSLNELGDPGVLLLCEGLRHPQCKLQTLRLDSCGLTAKACEDLSSMLGVNQTLTELYLTNNVLGNTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHRSLAALRVTKPYLDIGC", "length": 1001, "header": "tr|A0A5G2RN21-1|A0A5G2RN21_PIG Isoform 1 of NACHT, LRR and PYD domains-containing protein 12 OS=Sus scrofa OX=9823 GN=NLRP12 PE=3 SV=1 CANONICAL=A0A5G2RN21-1" }, "locus": { "chromosome": "6", "start_pos": 56424189, "end_pos": 56402783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080331.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080331.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074130.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074130.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "pmid": "" }, { "name": "negative regulation of interleukin-6 production", "id": "GO:0032715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032715", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "pmid": "" }, { "name": "negative regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901223", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "pmid": "" }, { "name": "negative regulation of interleukin-1 production", "id": "GO:0032692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032692", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "pmid": "" }, { "name": "positive regulation of MHC class I biosynthetic process", "id": "GO:0045345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045345", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "pmid": "" }, { "name": "negative regulation of Toll signaling pathway", "id": "GO:0045751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045751", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RN21", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" }, { "start_pos": 880, "end_pos": 882, "annotation": "n_glycosylation_sequon" }, { "start_pos": 937, "end_pos": 939, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RN21-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1001, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RN21-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RN21" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 211, "end_pos": 416, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5G2RN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RN21" }, { "id": "PS50824", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50824" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pyrin", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 95, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 540, "end_pos": 542 }, { "start_pos": 880, "end_pos": 882 }, { "start_pos": 937, "end_pos": 939 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RNH1-1", "uniprot_ac": "A0A5G2RNH1", "uniprot_id": "A0A5G2RNH1_PIG", "mass": { "chemical_mass": 59426.0, "monoisotopic_mass": 59426.0 }, "refseq": {}, "gene_names": [ { "name": "CDK17", "type": "recommended", "evidence": [ { "id": "A0A5G2RNH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1" } ] } ], "protein_names": [ { "name": "cyclin-dependent kinase", "type": "recommended", "evidence": [ { "id": "A0A5G2RNH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.22", "type": "synonym", "evidence": [ { "id": "A0A5G2RNH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CDK17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1", "locus": { "chromosome": "5", "start_pos": 87285474, "end_pos": 87179598, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000028182", "url": "https://www.ensembl.org/id/ENSSSCG00000028182" } ] } } ], "crossref": [ { "id": "A0A5G2RNH1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RNH1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000028182", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000028182", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07844", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07844", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07872", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07872", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056:SF128", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF128", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RNH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RNH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UR05", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UR05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UR05-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UR05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LDK7", "url": "https://www.uniprot.org/uniprotkb/I3LDK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LDK7-1", "url": "https://www.uniprot.org/uniprotkb/I3LDK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGKNRRQSMLF", "length": 522, "header": "tr|A0A5G2RNH1-1|A0A5G2RNH1_PIG Isoform 1 of cyclin-dependent kinase OS=Sus scrofa OX=9823 GN=CDK17 PE=3 SV=1 CANONICAL=A0A5G2RNH1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RNH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1/entry#A0A5G2RNH1-1", "sequence": { "sequence": "MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGKNRRQSMLF", "length": 522, "header": "tr|A0A5G2RNH1-1|A0A5G2RNH1_PIG Isoform 1 of cyclin-dependent kinase OS=Sus scrofa OX=9823 GN=CDK17 PE=3 SV=1 CANONICAL=A0A5G2RNH1-1" }, "locus": { "chromosome": "5", "start_pos": 87280345, "end_pos": 87241479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083326.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083326.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074406.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074406.1" } ] } }, { "isoform_ac": "A0ABB5UR05-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1/entry#A0ABB5UR05-1", "sequence": { "sequence": "MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQVCQYSV", "length": 460, "header": "tr|A0ABB5UR05-1|A0ABB5UR05_PIG Computationally mapped isoform of cyclin-dependent kinase OS=Sus scrofa OX=9823 GN=CDK17 PE=3 SV=1 CANONICAL=A0A5G2RNH1-1" }, "locus": { "chromosome": "5", "start_pos": 87279726, "end_pos": 87241479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107931.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107931.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082304.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082304.1" } ] } }, { "isoform_ac": "I3LDK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1/entry#I3LDK7-1", "sequence": { "sequence": "MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGVFVINHFTCRS", "length": 522, "header": "tr|I3LDK7-1|A0A5G2RNH1_PIG Computationally mapped isoform of cyclin-dependent kinase OS=Sus scrofa OX=9823 GN=CDK17 PE=3 SV=3 CANONICAL=A0A5G2RNH1-1" }, "locus": { "chromosome": "5", "start_pos": 87279821, "end_pos": 87241479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032012.4", "url": "https://www.ensembl.org/id/ENSSSCT00000032012.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022139.3", "url": "https://www.ensembl.org/id/ENSSSCP00000022139.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LDK7", "url": "https://www.uniprot.org/uniprotkb/I3LDK7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of cell cycle phase transition", "id": "GO:1901987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901987", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNH1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RNH1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 522, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RNH1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RNH1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RNH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNH1" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 191, "end_pos": 472, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 34, "end_pos": 36 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RNQ4-1", "uniprot_ac": "A0A5G2RNQ4", "uniprot_id": "A0A5G2RNQ4_PIG", "mass": { "chemical_mass": 35340.0, "monoisotopic_mass": 35340.0 }, "refseq": { "ac": "XP_003122738", "name": "olfactory receptor 4D6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122738" }, "gene_names": [ { "name": "LOC110255199", "type": "recommended", "evidence": [ { "id": "A0A5G2RNQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4" } ] }, { "name": "LOC110255199", "type": "synonym", "evidence": [ { "id": "XP_003122738", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122738" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A5G2RNQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4D6", "type": "synonym", "evidence": [ { "id": "XP_003122738", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122738" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110255199", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4", "locus": {} } ], "crossref": [ { "id": "A0A5G2RNQ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RNQ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110255199", "url": "https://www.ncbi.nlm.nih.gov/gene/110255199", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110255199", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255199", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RNQ4", "url": "https://www.orthodb.org/?gene=A0A5G2RNQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003122738", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122738", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RNQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RNQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQSNHTNVKEFVFLEITHFRELELFLFVVFLAVYVATVLGNALIVVTITCESPLHTPMYFLLRNKSVLDIAFSSVTVPKFLVDLLSERKAISYDGCMAQIFFFHFAGGADIFFLSVMAYDRYLAISKPLHYVTIMRREVWLALVVASWVGGGLHSIVQIILMLPLPFCGPNVLAAFYCDVPQVVKLACTDTFALELLMISNNGLVTLLWLLLLLGSYTSILVMLRSHSGEGRNKALSTCTSHILVVTLHFVPCVYIYCRPFSTLPMDTAVSISNTVLTPMLNPMIYTLRNQEMKSAMKRMQRWLGPFESNKLG", "length": 314, "header": "tr|A0A5G2RNQ4-1|A0A5G2RNQ4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110255199 PE=3 SV=1 CANONICAL=A0A5G2RNQ4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RNQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4/entry#A0A5G2RNQ4-1", "sequence": { "sequence": "MVQSNHTNVKEFVFLEITHFRELELFLFVVFLAVYVATVLGNALIVVTITCESPLHTPMYFLLRNKSVLDIAFSSVTVPKFLVDLLSERKAISYDGCMAQIFFFHFAGGADIFFLSVMAYDRYLAISKPLHYVTIMRREVWLALVVASWVGGGLHSIVQIILMLPLPFCGPNVLAAFYCDVPQVVKLACTDTFALELLMISNNGLVTLLWLLLLLGSYTSILVMLRSHSGEGRNKALSTCTSHILVVTLHFVPCVYIYCRPFSTLPMDTAVSISNTVLTPMLNPMIYTLRNQEMKSAMKRMQRWLGPFESNKLG", "length": 314, "header": "tr|A0A5G2RNQ4-1|A0A5G2RNQ4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110255199 PE=3 SV=1 CANONICAL=A0A5G2RNQ4-1" }, "locus": { "chromosome": "AEMK02000584.1", "start_pos": 90130, "end_pos": 89189, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061485.2", "url": "https://www.ensembl.org/id/ENSSSCT00000061485.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074561.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074561.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110255199", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255199", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RNQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RNQ4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RNQ4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RNQ4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RNQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RNQ4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1TXL1-1", "uniprot_ac": "A0A5K1TXL1", "uniprot_id": "A0A5K1TXL1_PIG", "mass": { "chemical_mass": 66637.0, "monoisotopic_mass": 66637.0 }, "refseq": {}, "gene_names": [ { "name": "PLS3", "type": "recommended", "evidence": [ { "id": "A0A5K1TXL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" } ] } ], "protein_names": [ { "name": "Plastin-3", "type": "recommended", "evidence": [ { "id": "A0A5K1TXL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1/entry#names_and_taxonomy" } ] }, { "name": "T-plastin", "type": "synonym", "evidence": [ { "id": "A0A5K1TXL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Actin-bundling protein.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TXL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1#function" }, { "database": "UniProtKB", "id": "ARBA00044724", "url": "https://www.uniprot.org/uniprotkb/ARBA00044724#function" }, { "database": "UniProtKB", "id": "A0A5K1TXL2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL2#function" }, { "database": "UniProtKB", "id": "F1RWT2", "url": "https://www.uniprot.org/uniprotkb/F1RWT2#function" }, { "database": "UniProtKB", "id": "K7GQS5", "url": "https://www.uniprot.org/uniprotkb/K7GQS5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TXL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PLS3", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1", "locus": { "chromosome": "X", "start_pos": 94971659, "end_pos": 94885118, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012597", "url": "https://www.ensembl.org/id/ENSSSCG00000012597" } ] } } ], "crossref": [ { "id": "A0A5K1TXL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1TXL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012597", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012597", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21292", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21292", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21328", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21328", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21331", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21331", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21334", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21334", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TVNHLYV", "url": "https://omabrowser.org/oma/group/TVNHLYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19961", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19961", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19961:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19961:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5K1TXL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1TXL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1TXL2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1TXL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWT2", "url": "https://www.uniprot.org/uniprotkb/F1RWT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWT2-1", "url": "https://www.uniprot.org/uniprotkb/F1RWT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GQS5", "url": "https://www.uniprot.org/uniprotkb/K7GQS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GQS5-1", "url": "https://www.uniprot.org/uniprotkb/K7GQS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLDGDRNKDGKISFDEFVYVIKEGTVGTRWITIKTATLPRNHLVIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLSEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV", "length": 595, "header": "tr|A0A5K1TXL1-1|A0A5K1TXL1_PIG Isoform 1 of Plastin-3 OS=Sus scrofa OX=9823 GN=PLS3 PE=1 SV=2 CANONICAL=A0A5K1TXL1-1" }, "isoforms": [ { "isoform_ac": "A0A5K1TXL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1/entry#A0A5K1TXL1-1", "sequence": { "sequence": "MLDGDRNKDGKISFDEFVYVIKEGTVGTRWITIKTATLPRNHLVIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLSEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV", "length": 595, "header": "tr|A0A5K1TXL1-1|A0A5K1TXL1_PIG Isoform 1 of Plastin-3 OS=Sus scrofa OX=9823 GN=PLS3 PE=1 SV=2 CANONICAL=A0A5K1TXL1-1" }, "locus": { "chromosome": "X", "start_pos": 94970554, "end_pos": 94942194, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033683.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033683.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029168.4", "url": "https://www.ensembl.org/id/ENSSSCP00000029168.4" } ] } }, { "isoform_ac": "A0A5K1TXL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1/entry#A0A5K1TXL2-1", "sequence": { "sequence": "MLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLSEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV", "length": 538, "header": "tr|A0A5K1TXL2-1|A0A5K1TXL1_PIG Computationally mapped isoform of Plastin-3 OS=Sus scrofa OX=9823 GN=PLS3 PE=1 SV=1 CANONICAL=A0A5K1TXL1-1" }, "locus": { "chromosome": "X", "start_pos": 94970554, "end_pos": 94942194, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033699.3", "url": "https://www.ensembl.org/id/ENSSSCT00000033699.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029738.3", "url": "https://www.ensembl.org/id/ENSSSCP00000029738.3" } ] } }, { "isoform_ac": "F1RWT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1/entry#F1RWT2-1", "sequence": { "sequence": "MLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKLIDFSNSVKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLSEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV", "length": 579, "header": "tr|F1RWT2-1|A0A5K1TXL1_PIG Computationally mapped isoform of Plastin-3 OS=Sus scrofa OX=9823 GN=PLS3 PE=1 SV=4 CANONICAL=A0A5K1TXL1-1" }, "locus": { "chromosome": "X", "start_pos": 94970554, "end_pos": 94942194, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013776.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013776.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013396.4", "url": "https://www.ensembl.org/id/ENSSSCP00000013396.4" } ] } }, { "isoform_ac": "K7GQS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1/entry#K7GQS5-1", "sequence": { "sequence": "MLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLSEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV", "length": 570, "header": "tr|K7GQS5-1|A0A5K1TXL1_PIG Computationally mapped isoform of Plastin-3 OS=Sus scrofa OX=9823 GN=PLS3 PE=1 SV=3 CANONICAL=A0A5K1TXL1-1" }, "locus": { "chromosome": "X", "start_pos": 94970554, "end_pos": 94942194, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036629.4", "url": "https://www.ensembl.org/id/ENSSSCT00000036629.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030249.3", "url": "https://www.ensembl.org/id/ENSSSCP00000030249.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 319, "start_aa": "Thr", "end_pos": 319, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr319", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "K7GQS5", "url": "https://www.uniprot.org/uniprotkb/K7GQS5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PE96-1", "protein_name": "Plastin-3", "gene_name": "PLS3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVTMQISKDELEELKEAFAKVDLNSNGFICDYELHELFKEANLPLPGYKVREIIQKLMIDSDKNKDGKISFEEFVYIFQEVKSSDIAKTFRKAINRKEGICAIGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLREGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGENLEDLMKLSPEELLLRWANFHLENAGWHKINNFSTDIKLTDFGNSVKDSRAYFHLLNQIAPKGQKEGEPQIDINMSGFNEKDDLRRAEYMLQQADRLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYGDLQDALVILQLYEKIKVPVDWNKVNKPPYPKLGANMKKLENCNYAVDLGKHPAKFSLVGIGGQDLNDGNPTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNQTLKEAGKSTSIQNFKDKTISTSLAVVDLIDAIQPGCINYDLVKTGHLSEDDKQNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV", "length": 637 }, "evidence": [ { "id": "A0A5K1TXL1", "url": "https://omabrowser.org/oma/group/A0A5K1TXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A7E3Q8-1", "protein_name": "Plastin-3", "gene_name": "PLS3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVSWVNRTLNEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGTLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV", "length": 630 }, "evidence": [ { "id": "A0A5K1TXL1", "url": "https://omabrowser.org/oma/group/A0A5K1TXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P13797-1", "protein_name": "Plastin-3", "gene_name": "PLS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV", "length": 630 }, "evidence": [ { "id": "A0A5K1TXL1", "url": "https://omabrowser.org/oma/group/A0A5K1TXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63598-1", "protein_name": "Plastin-3", "gene_name": "Pls3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFNEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYVDLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKNQAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVMEDLGEGQKATDDIIVNWVNGTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKTGNLTEEDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKSV", "length": 630 }, "evidence": [ { "id": "A0A5K1TXL1", "url": "https://omabrowser.org/oma/group/A0A5K1TXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6DG81-1", "protein_name": "Plastin-3", "gene_name": "pls3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGKISKEELEELREAFGKVDLNGNGFICDHELHDLFKEANLPLPGYKVREIIQKLMEEGDKNKDNMISFDEFVSIFQELKSGDIAKSFRKAINRKEGILAIGGTSELSSAGTQHSFSEEERFAFVNWINTALEHDPDCKHKLPMNPNTDALFKAVGDGIVLCKMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGALDLREGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEDLMKLSPEELLLRWANFHLENAGWSKINNFSHDIKDSRAYFHLLNQIAPKGQKDGESRIDIDMSGFTEKDDLKRAECMLLQADKLGCRQFVTSTDVMSGNPKLNLAFVANLFNKYPALTKPENQDINWGLLEGETREERTFRNWMNSLGVNPHVNHLYGDLQDALVILQLYEKIKVPVDWNNKVNKPPYPKLGANMKKLENCNYAVELGKTKANFSLVGIGGQDLNDGNPTLTLALVWQLMRRYTLNVLENLGDGQKVNDDVIVSWVNKTLSQAGKSTKISNFKDKEISSSLAVLDLIDAIQPSSINYDLVKRGSLSDGDKLDNAKYAVSMARKIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRA", "length": 627 }, "evidence": [ { "id": "A0A5K1TXL1", "url": "https://omabrowser.org/oma/group/A0A5K1TXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7G188-1", "protein_name": "Fimbrin-1", "gene_name": "FIM1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSGYVGVVVSDPWLQSQFTQVELRTLNSKYVSVKNQNGKVTIEDLPPLFAKLKALSATFKEDEIKGMLGELGSDTSTDVSFEEFLKIYLNLLSKAAEKSGGHHKNSSSFLKACTTTLLHTIYQSEKGPFVQHINRYLGDDPFLKQFLPLDPHSNQLYELVKDGVLLCKLINVAVPGTIDERAINTKRVLNPWERNENHTLCLNSAKAVGCSVVNIGTQDLAEGRPHLVLGLISQLIKIQVLADLNLKKTPQLVELLEDSDDVEELLRLPPEKVLLKWMNFHLKKGGYKKTVSNFSADLKDAQAYAFLLNVLAPEHCDPATLDAKDPLERAELVLSHAERMNCKRYLTAEEIVEGSSTLNLAFVAQIFHERNGLNKDGKYAFAEMMTEDVETCRDERCYRLWINSLGIDSYVNNVFEDVRNGWILLEVLDKVSPSSVNWKHASKPPIKMPFRKVENCNQVIKIGKQLKFSLVNVAGNDIVQGNKKLILGLLWQLMRFHMLQLLKSLRSRTLGKEMTDADILSWANRKVRTMGRKLQIESFKDKSLSSGLFFLNLLWAVEPRVVNWNLVTKGETDDEKRLNATYIVSVARKLGCSVFLLPEDIVEVNQKMILILTASIMYWSLQRHSRESSDSSSTQSTTTTCTSTASSPAPSVTEEEEVSSLSGEVTSLAVGDAVSEITTVSEEASIE", "length": 687 }, "evidence": [ { "id": "A0A5K1TXL1", "url": "https://omabrowser.org/oma/group/A0A5K1TXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q99K51-1", "protein_name": "Plastin-3", "gene_name": "Pls3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMVDGDRNKDGKISFNEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKNPAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVLEDLGEGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV", "length": 630 }, "evidence": [ { "id": "A0A5K1TXL1", "url": "https://omabrowser.org/oma/group/A0A5K1TXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TXL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TXL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TXL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" } ], "pmid": "" }, { "name": "actin filament bundle", "id": "GO:0032432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032432", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TXL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TXL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TXL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TXL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" } ], "pmid": "" }, { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TXL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" } ], "pmid": "" }, { "name": "actin filament network formation", "id": "GO:0051639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051639", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1TXL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1TXL1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 595, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1TXL1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1TXL1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1TXL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 204, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5K1TXL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1TXL1" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 27, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 319 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 289, "end_pos": 291 }, { "start_pos": 294, "end_pos": 296 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 541, "end_pos": 543 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1UB60-1", "uniprot_ac": "A0A5K1UB60", "uniprot_id": "A0A5K1UB60_PIG", "mass": { "chemical_mass": 69186.0, "monoisotopic_mass": 69186.0 }, "refseq": {}, "gene_names": [ { "name": "ALCAM", "type": "recommended", "evidence": [ { "id": "A0A5K1UB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ] } ], "protein_names": [ { "name": "CD166 antigen", "type": "recommended", "evidence": [ { "id": "A0A5K1UB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60/entry#names_and_taxonomy" } ] }, { "name": "Activated leukocyte cell adhesion molecule", "type": "synonym", "evidence": [ { "id": "A0A5K1UB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ALCAM", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60", "locus": { "chromosome": "13", "start_pos": 153794993, "end_pos": 153998208, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011946", "url": "https://www.ensembl.org/id/ENSSSCG00000011946" } ] } } ], "crossref": [ { "id": "A0A5K1UB60", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1UB60", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011946", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011946", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "397269", "url": "https://www.ncbi.nlm.nih.gov/gene/397269", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "K7GLE8", "url": "https://www.orthodb.org/?gene=K7GLE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11973", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11973", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11973:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11973:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UB60-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SL34", "url": "https://www.uniprot.org/uniprotkb/F1SL34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SL34-1", "url": "https://www.uniprot.org/uniprotkb/F1SL34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GLE8", "url": "https://www.uniprot.org/uniprotkb/K7GLE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GLE8-1", "url": "https://www.uniprot.org/uniprotkb/K7GLE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKAAPSCRLVFCLLISAAALRPGLGLYTVNSAYGDNIIMPCRLDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKNRLSLSENYTLSISNAKISDEKRFVCMLVTEDNVFEAPTVVKVFKQPSKPEIVSKAPFLETEKLKKLGECISKDSYPDGNITWYRNGKVLQPLEEAVVIIFKKQMDPVTQLYTMTSSLEYKTTKADIQMPFTCSVTYYGPSGQKTVYSEQAIFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTTITVHYLDLSLNPSGEVTKQIGDALPVSCTISASRNATVVWMKDNVRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGNKIYEYHFKFFFENLISGFFYDLGSTSYFNCNDIVGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENKEKVNDQAKLIVGIVVGLLLAALVAGVVYWLYMKKSKTASKHVNKDLGNLEENKKLEENNHKTEA", "length": 619, "header": "tr|A0A5K1UB60-1|A0A5K1UB60_PIG Isoform 1 of CD166 antigen OS=Sus scrofa OX=9823 GN=ALCAM PE=1 SV=1 CANONICAL=A0A5K1UB60-1" }, "isoforms": [ { "isoform_ac": "A0A5K1UB60-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60/entry#A0A5K1UB60-1", "sequence": { "sequence": "MASKAAPSCRLVFCLLISAAALRPGLGLYTVNSAYGDNIIMPCRLDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKNRLSLSENYTLSISNAKISDEKRFVCMLVTEDNVFEAPTVVKVFKQPSKPEIVSKAPFLETEKLKKLGECISKDSYPDGNITWYRNGKVLQPLEEAVVIIFKKQMDPVTQLYTMTSSLEYKTTKADIQMPFTCSVTYYGPSGQKTVYSEQAIFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTTITVHYLDLSLNPSGEVTKQIGDALPVSCTISASRNATVVWMKDNVRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGNKIYEYHFKFFFENLISGFFYDLGSTSYFNCNDIVGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENKEKVNDQAKLIVGIVVGLLLAALVAGVVYWLYMKKSKTASKHVNKDLGNLEENKKLEENNHKTEA", "length": 619, "header": "tr|A0A5K1UB60-1|A0A5K1UB60_PIG Isoform 1 of CD166 antigen OS=Sus scrofa OX=9823 GN=ALCAM PE=1 SV=1 CANONICAL=A0A5K1UB60-1" }, "locus": { "chromosome": "13", "start_pos": 153997505, "end_pos": 153799294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032688.4", "url": "https://www.ensembl.org/id/ENSSSCT00000032688.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030207.3", "url": "https://www.ensembl.org/id/ENSSSCP00000030207.3" } ] } }, { "isoform_ac": "F1SL34-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60/entry#F1SL34-1", "sequence": { "sequence": "MPCRLDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKNRLSLSENYTLSISNAKISDEKRFVCMLVTEDNVFEAPTVVKVFKQPSKPEIVSKAPFLETEKLKKLGECISKDSYPDGNITWYRNGKVLQPLEEAVVIIFKKQMDPVTQLYTMTSSLEYKTTKADIQMPFTCSVTYYGPSGQKTVYSEQAIFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTTITVHYLDLSLNPSGEVTKQIGDALPVSCTISASRNATVVWMKDNVRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENKEKVNDQAKLIVGIVVGLLLAALVAGVVYWLYMKKSKTASKHVNKDLGNLEENKKLEENNHKTEA", "length": 543, "header": "tr|F1SL34-1|A0A5K1UB60_PIG Computationally mapped isoform of CD166 antigen OS=Sus scrofa OX=9823 GN=ALCAM PE=1 SV=5 CANONICAL=A0A5K1UB60-1" }, "locus": { "chromosome": "13", "start_pos": 153852848, "end_pos": 153799294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013072.6", "url": "https://www.ensembl.org/id/ENSSSCT00000013072.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012727.5", "url": "https://www.ensembl.org/id/ENSSSCP00000012727.5" } ] } }, { "isoform_ac": "K7GLE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60/entry#K7GLE8-1", "sequence": { "sequence": "MASKAAPSCRLVFCLLISAAALRPGLGLYTVNSAYGDNIIMPCRLDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKNRLSLSENYTLSISNAKISDEKRFVCMLVTEDNVFEAPTVVKVFKQPSKPEIVSKAPFLETEKLKKLGECISKDSYPDGNITWYRNGKVLQPLEEAVVIIFKKQMDPVTQLYTMTSSLEYKTTKADIQMPFTCSVTYYGPSGQKTVYSEQAIFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTTITVHYLDLSLNPSGEVTKQIGDALPVSCTISASRNATVVWMKDNVRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSANENKEKVNDQAKLIVGIVVGLLLAALVAGVVYWLYMKKSKTASKHVNKDLGNLEENKKLEENNHKTEA", "length": 570, "header": "tr|K7GLE8-1|A0A5K1UB60_PIG Computationally mapped isoform of CD166 antigen OS=Sus scrofa OX=9823 GN=ALCAM PE=1 SV=3 CANONICAL=A0A5K1UB60-1" }, "locus": { "chromosome": "13", "start_pos": 153997505, "end_pos": 153799294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000034028.4", "url": "https://www.ensembl.org/id/ENSSSCT00000034028.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028677.3", "url": "https://www.ensembl.org/id/ENSSSCP00000028677.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SL34", "url": "https://www.uniprot.org/uniprotkb/F1SL34" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "pmid": "" }, { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "pmid": "" }, { "name": "immunological synapse", "id": "GO:0001772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001772", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UB60", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 516, "end_pos": 518, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1UB60-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 619, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1UB60-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1UB60" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1UB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UB60" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 125, "end_pos": 234, "start_aa": "Pro", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 516, "end_pos": 518 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1UBC7-1", "uniprot_ac": "A0A5K1UBC7", "uniprot_id": "A0A5K1UBC7_PIG", "mass": { "chemical_mass": 64494.0, "monoisotopic_mass": 64494.0 }, "refseq": {}, "gene_names": [ { "name": "PGLYRP2", "type": "recommended", "evidence": [ { "id": "A0A5K1UBC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ] } ], "protein_names": [ { "name": "Peptidoglycan recognition protein 2", "type": "synonym", "evidence": [ { "id": "A0A5K1UBC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PGLYRP2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7", "locus": { "chromosome": "2", "start_pos": 62140184, "end_pos": 62134533, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000025560", "url": "https://www.ensembl.org/id/ENSSSCG00000025560" } ] } } ], "crossref": [ { "id": "ENSSSCG00000025560", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000025560", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06583", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06583", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MDCPPII", "url": "https://omabrowser.org/oma/group/MDCPPII/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11022", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11022", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11022:SF66", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11022:SF66", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01510", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01510", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6803157", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6803157", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UBC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LD86", "url": "https://www.uniprot.org/uniprotkb/I3LD86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LD86-1", "url": "https://www.uniprot.org/uniprotkb/I3LD86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPGNWKTTMVVRGILLILYGLLLQPEPGTATLPLLMDSVIQALAELEQKSPATEAGHIASMWLLSAQGSGAHNPLPRFLLEGQSLKTAKLAPPSLSPEFQGLIEEVARHGVQDGKEYGVVLAPDGSTVAVEPLLAGLEAGLQGHRVVNLPLDSTATFPDIGATVPDLKATSSAHKDTSADVNSADVGTLSPNVRDTDVDAEVTFLDVRPSSTGVQVTSPDVQASSPDTKAKSPTTVDSLLMVTLARDLGLHFLQGAQTESNSGLGTEGCWDQLSLPRTFTLLDPEASPLTMAFLNGALDGALLGDYLSKVPEPRPPLSHLLNQYYGAGVAGDPGLRSNFRRQNGAALTLTPNLTQQVWGTLILLQRLEPAHPQLQGMSQEQLAQVATHAAKEFTEAFLGCPAIHPRCRWGAAPYRGSPKPLKLPLGFLYIHHTYVPARPCTDFALCAANMRSMQRFHQDTQGWDDIGYSFVVGSDGYVYEGRGWHWVGAHTRGHNSRGFGVALIGNYTAELPSEAALRAVRDELPHCAVRAGLLQPDYALLGHRQLVRTDCPGDALFNMLRTWPRFNMNVKPRTARRASGRSKRRLPLMIPLATDLQ", "length": 598, "header": "tr|A0A5K1UBC7-1|A0A5K1UBC7_PIG Isoform 1 of Peptidoglycan recognition protein 2 OS=Sus scrofa OX=9823 GN=PGLYRP2 PE=3 SV=1 CANONICAL=A0A5K1UBC7-1" }, "isoforms": [ { "isoform_ac": "A0A5K1UBC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7/entry#A0A5K1UBC7-1", "sequence": { "sequence": "MSPGNWKTTMVVRGILLILYGLLLQPEPGTATLPLLMDSVIQALAELEQKSPATEAGHIASMWLLSAQGSGAHNPLPRFLLEGQSLKTAKLAPPSLSPEFQGLIEEVARHGVQDGKEYGVVLAPDGSTVAVEPLLAGLEAGLQGHRVVNLPLDSTATFPDIGATVPDLKATSSAHKDTSADVNSADVGTLSPNVRDTDVDAEVTFLDVRPSSTGVQVTSPDVQASSPDTKAKSPTTVDSLLMVTLARDLGLHFLQGAQTESNSGLGTEGCWDQLSLPRTFTLLDPEASPLTMAFLNGALDGALLGDYLSKVPEPRPPLSHLLNQYYGAGVAGDPGLRSNFRRQNGAALTLTPNLTQQVWGTLILLQRLEPAHPQLQGMSQEQLAQVATHAAKEFTEAFLGCPAIHPRCRWGAAPYRGSPKPLKLPLGFLYIHHTYVPARPCTDFALCAANMRSMQRFHQDTQGWDDIGYSFVVGSDGYVYEGRGWHWVGAHTRGHNSRGFGVALIGNYTAELPSEAALRAVRDELPHCAVRAGLLQPDYALLGHRQLVRTDCPGDALFNMLRTWPRFNMNVKPRTARRASGRSKRRLPLMIPLATDLQ", "length": 598, "header": "tr|A0A5K1UBC7-1|A0A5K1UBC7_PIG Isoform 1 of Peptidoglycan recognition protein 2 OS=Sus scrofa OX=9823 GN=PGLYRP2 PE=3 SV=1 CANONICAL=A0A5K1UBC7-1" }, "locus": { "chromosome": "2", "start_pos": 62140156, "end_pos": 62135645, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023031.4", "url": "https://www.ensembl.org/id/ENSSSCT00000023031.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028092.2", "url": "https://www.ensembl.org/id/ENSSSCP00000028092.2" } ] } }, { "isoform_ac": "I3LD86-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7/entry#I3LD86-1", "sequence": { "sequence": "LVPLKVIFHMAVKGTNVIPPPTATLPLLMDSVIQALAELEQKSPATEAGHIASMWLLSAQGSGAHNPLPRFLLEGQSLKTAKLAPPSLSPEFQGLIEEVARHGVQDGKEYGVVLAPDGSTVAVEPLLAGLEAGLQGHRVVNLPLDSTATFPDIGATVPDLKATSSAHKDTSADVNSADVGTLSPNVRDTDVDAEVTFLDVRPSSTGVQVTSPDVQASSPDTKAKSPTTVDSLLMVTLARDLGLHFLQGAQTESNSGLGTEGCWDQLSLPRTFTLLDPEASPLTMAFLNGALDGALLGDYLSKVPEPRPPLSHLLNQYYGAGVAGDPGLRSNFRRQNGAALTLTPNLTQQVWGTLILLQRLEPAHPQLQGMSQEQLAQVATHAAKEFTEAFLGCPAIHPRCRWGAAPYRGSPKPLKLPLGFLYIHHTYVPARPCTDFALCAANMRSMQRFHQDTQGWDDIGYSFVVGSDGYVYEGRGWHWVGAHTRGHNSRGFGVALIGNYTAELPSEAALRAVRDELPHCAVRAGLLQPDYALLGHRQLVRTDCPGDALFNMLRTWPRFNMNVKPRTARRASGRSKRRLPLMIPLATDLQ", "length": 590, "header": "tr|I3LD86-1|A0A5K1UBC7_PIG Computationally mapped isoform of Peptidoglycan recognition protein 2 OS=Sus scrofa OX=9823 GN=PGLYRP2 PE=3 SV=3 CANONICAL=A0A5K1UBC7-1" }, "locus": { "chromosome": "2", "start_pos": 62140156, "end_pos": 62136550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022764.4", "url": "https://www.ensembl.org/id/ENSSSCT00000022764.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022015.3", "url": "https://www.ensembl.org/id/ENSSSCP00000022015.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LD86", "url": "https://www.uniprot.org/uniprotkb/I3LD86" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6803157", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6803157", "resource": "Reactome", "description": "Antimicrobial peptides" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IJX9-1", "protein_name": "Peptidoglycan recognition protein 6", "gene_name": "pglyrp6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMGRQFISVCLRKGQDGFKRRASSEANTQSDFIIRGYLALNYSVFMMDLRLFSLLMLFACGIAEATTLKRMDDFISAVESIEAVNPALSMLDVLKGLRKASGLETDLSQQLLGDAHPELTMDPSVASNIHELINHHVSDITEEGVVLTLDGSNVALAPLLLGLEAGLQSIDLYPLTLTENLLNSFVHHVQNQESSALLGTKGYWDSIKSPRVYTLSGLPSLATDALIIGGMDGFILGSEMASSDHPEESLSSLLRSYYSQKLDDAAPRLISQKRRMNFRNMADFSLMKTQVVRALTVRRNLNQDERKKLDDVVNEGFEEFVHVYAVCPNIITRSQWGAASYIGSPSYLSLPVRYLFIHHTYQPSKPCTTFEQCAAEMRSMQRYHQQSNGWSDIGYSFVAGSDGNLYEGRGWNWVGAHTYGYNSIGYGVCFIGDYTSTLPASSAMNMVRYDFTYCATNGGRLSKSYSLYGHRQAAATECPGNTLYRQIQTWERYQSYLP", "length": 498 }, "evidence": [ { "id": "A0A5K1UBC7", "url": "https://omabrowser.org/oma/group/A0A5K1UBC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8C2LE68-1", "protein_name": "N-acetylmuramoyl-L-alanine amidase isoform X2", "gene_name": "Pglyrp2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMKAGGVLWVLLRLLLWPEPGTASSLPLVMDSIIQALAELEQKVLVTEASGTASSWILSASNSSPHNSLHQHLLRKTPSHNTMEPDPHSLSPELQALISEVAQHVVQDGQEYGVVLAPDGSTVAVKPLLIGLEAGLQEHNVTNLPSECLAMPCDAGDTLTNIGAIWPGLMDASTNASFTDVGATLPNDKAKTPTTVDRLLAATLARDLGLMFLNSSQTQSPPGLGTEGCWNQLSTRRVFTLLDPKASRLTMAFLNGALDGALLGDHLSRVSKPRPPLSHLLKEYYGAGVAGDPRFRSNFRRQNGAALTSVPTLAQKVWEALVLLQRLEPGHPQLQNMSQEELARVATFATKEFTETFLGCPAILPRCRWGAAPYRGNPRPLRLPLGFLYVHHTYVPAPPCTTFQSCAANMRSMQRFHQNERHWDDIGYSFVVGSDGYVYEGRGWRWVGAHTRGHNSRGFGVAIVGNYTGSLPSDTALNTVRDVLPSCAIRSGHLQPDYKVLGHRQLVHSDCPGDALFNLLRTWPHFAEAEN", "length": 531 }, "evidence": [ { "id": "A0A5K1UBC7", "url": "https://omabrowser.org/oma/group/A0A5K1UBC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BH94-1", "protein_name": "Peptidoglycan recognition protein 1", "gene_name": "PGLYRP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSFGNWKPTVVVQGILWILYGLLLQPEPGTATLPLLMDSVIQALAELEQKAPATEAGHSAAAWLLTAQGSGTHSPLYHFLLEGKSLNTTELDPPSLSPELRGLMGEVARHSVQDGKEYGVVLAPDGSTVAVEPLLAGLWAGLQGHRIVNLSLESTATPPDAGVTFPDLGPTSPGLSDASPDVTSGDVRAVSPNVSTKDTDVRATSPEVRPGSPDVQASSPDTKAKLPTAVDSLLVVTLARGLGLNFLQGPQTWNHSGLGTEGCWDQLSVPRTFTLLDPEASPLTTAFLNGALDGALLGDYLSRTPAPRPPLSHLLSQYYGAGVAGDPGFRSNFRRHNGAALTSAPSLTQQVWGALILLQRLEPAHPHLQGMSQEELAQVATHATKEFTEAFLGCPAIHPRCRWGAAPYQGRPTLLKLPLGFLYVHHTYLPAPPCTSFESCAADMRSMQRFHQQTRGWSDIGYSFVVGSDGYVYEGRGWHWVGAHTLGHNSRGFGVALIGNYTAVLPSEAALLAVRDELPRCAIRAGLLRPDYALLGHRQLVPTECPGDLLFNLLRTWPHFDKNVKPRTARRASSRSKRRPPPTILLSTDLQ", "length": 591 }, "evidence": [ { "id": "A0A5K1UBC7", "url": "https://omabrowser.org/oma/group/A0A5K1UBC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0R485-1", "protein_name": "Peptidoglycan recognition protein 2", "gene_name": "Pglyrp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKAWGVLWIVLGLSLWPKPGTASSLPMVMDSIIQALEELEQKVLVTEAGVTASAWILSAKNYSSHNSLHQHLLLKAPSQNTTEPDTHSLSPELQALISEVAQHDVRDGQEYGVVLAPDGSTVAVKPLLVGLEAGLQGRSVANLSSDCLDTCDTGAIWPGLKDAFTNVSSPDAGATLPNDKAKTPTTVDRLLAVTLAGDLGLTFLHRSQTWSPPGLGIEGCWDQLSAPRVFTLLDHKASRLTMAFLNGALDGALLGAHLSRIPKPHPPLSRLLREYYGAGVDGDPAFRSNFRRQNGVALTSAPTLAQQVWEALVLLQKLEPGHPRLQNMSQKQLAQVATFATKEFTEAFLGCPAIHPRCRWGAAPYRGHPTPLRLPLGLLYVHHTYVPAPPCTTFQSCAADMRSMQRFHQNVRGWADIGYSFVVGSDGYVYQGRGWHWVGAHTLGYNSRGFGVAFVGNYTGSLPSEAALNTVRDVLPSCAIRAGLLRPDYKLFGHRQLGKTDCPGNALFNLLRTWPHFTVVEN", "length": 522 }, "evidence": [ { "id": "A0A5K1UBC7", "url": "https://omabrowser.org/oma/group/A0A5K1UBC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VCS0-1", "protein_name": "N-acetylmuramoyl-L-alanine amidase", "gene_name": "Pglyrp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKAWGALWIVLGLLLWPEPGAASSLPLLMDSIIQALAELEQKVPVTEASITASAWILSAKNSSTHNSLHQRLLLKAPSHNTTEPDPHSLSPELQALISEVAQHDVQNGREYGVVLAPDGSTVAVKPLLFGLEAGLQAHSVANLPSDCLAIPCDTGDTLANIRATWPGLMDAFPNASSPDVGATLPNDKAKTPTTVDRLLAITLAGDLGLTFLHRSQTWSPPGLGTEGCWDQLTAPRVFTLLDPQASRLTMAFLNGALDGALLGNHLSQIPRPHPPLSHLLREYYGAGVNGDPVFRSNFRRQNGAALTSAPTLAQQVWEALVLLQKLEPEHLQLQNISQEQLAQVATLATKEFTEAFLGCPAIHPRCRWGAAPYRGHPTPLRLPLGFLYVHHTYVPAPPCTTFQSCAADMRSMQRFHQDVRKWDDIGYSFVVGSDGYLYQGRGWHWVGAHTRGYNSRGFGVAFVGNYTGSLPNEAALNTVRDALPSCAIRAGLLRPDYKLLGHRQLVLTHCPGNALFNLLRTWPHFTEVEN", "length": 530 }, "evidence": [ { "id": "A0A5K1UBC7", "url": "https://omabrowser.org/oma/group/A0A5K1UBC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96PD5-1", "protein_name": "N-acetylmuramoyl-L-alanine amidase", "gene_name": "PGLYRP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQGVLWILLGLLLWSDPGTASLPLLMDSVIQALAELEQKVPAAKTRHTASAWLMSAPNSGPHNRLYHFLLGAWSLNATELDPCPLSPELLGLTKEVARHDVREGKEYGVVLAPDGSTVAVEPLLAGLEAGLQGRRVINLPLDSMAAPWETGDTFPDVVAIAPDVRATSSPGLRDGSPDVTTADIGANTPDATKGCPDVQASLPDAKAKSPPTMVDSLLAVTLAGNLGLTFLRGSQTQSHPDLGTEGCWDQLSAPRTFTLLDPKASLLTMAFLNGALDGVILGDYLSRTPEPRPSLSHLLSQYYGAGVARDPGFRSNFRRQNGAALTSASILAQQVWGTLVLLQRLEPVHLQLQCMSQEQLAQVAANATKEFTEAFLGCPAIHPRCRWGAAPYRGRPKLLQLPLGFLYVHHTYVPAPPCTDFTRCAANMRSMQRYHQDTQGWGDIGYSFVVGSDGYVYEGRGWHWVGAHTLGHNSRGFGVAIVGNYTAALPTEAALRTVRDTLPSCAVRAGLLRPDYALLGHRQLVRTDCPGDALFDLLRTWPHFTATVKPRPARSVSKRSRREPPPRTLPATDLQ", "length": 576 }, "evidence": [ { "id": "A0A5K1UBC7", "url": "https://omabrowser.org/oma/group/A0A5K1UBC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "peptidoglycan binding", "id": "GO:0042834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042834", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ], "pmid": "" }, { "name": "N-acetylmuramoyl-L-alanine amidase activity", "id": "GO:0008745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008745", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ], "pmid": "" }, { "name": "peptidoglycan immune receptor activity", "id": "GO:0016019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016019", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ], "pmid": "" }, { "name": "detection of bacterium", "id": "GO:0016045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016045", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ], "pmid": "" }, { "name": "peptidoglycan catabolic process", "id": "GO:0009253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009253", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UBC7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1UBC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" }, { "id": "SM00644", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00644" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-acetylmuramoyl-L-alanine amidase", "eco_id": "ECO_0000259", "start_pos": 414, "end_pos": 554, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5K1UBC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UBC7" }, { "id": "SM00701", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00701" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidoglycan recognition protein family", "eco_id": "ECO_0000259", "start_pos": 402, "end_pos": 548, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 353, "end_pos": 355 }, { "start_pos": 507, "end_pos": 509 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1UCI1-1", "uniprot_ac": "A0A5K1UCI1", "uniprot_id": "A0A5K1UCI1_PIG", "mass": { "chemical_mass": 120495.0, "monoisotopic_mass": 120495.0 }, "refseq": { "ac": "XP_005657869", "name": "APC membrane recruitment protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657869" }, "gene_names": [ { "name": "AMER1", "type": "recommended", "evidence": [ { "id": "A0A5K1UCI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ] }, { "name": "AMER1", "type": "synonym", "evidence": [ { "id": "XP_005657869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657869" } ] } ], "protein_names": [ { "name": "APC membrane recruitment protein 1", "type": "synonym", "evidence": [ { "id": "XP_005657869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657869" }, { "id": "A0A5K1UCI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AMER1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1", "locus": { "chromosome": "X", "start_pos": 50844683, "end_pos": 50864032, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012361", "url": "https://www.ensembl.org/id/ENSSSCG00000012361" } ] } } ], "crossref": [ { "id": "A0A5K1UCI1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1UCI1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012361", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012361", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100512031", "url": "https://www.ncbi.nlm.nih.gov/gene/100512031", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512031", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512031", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRDFPGT", "url": "https://omabrowser.org/oma/group/WRDFPGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5K1UCI1", "url": "https://www.orthodb.org/?gene=A0A5K1UCI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22237", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22237", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22237:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22237:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-195253", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-195253", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-196299", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-196299", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4641262", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4641262", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005657869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657869", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UCI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METRKDESPQAKGAAVSVDTQDQGAENGAKNKAAEMIEGPASEPPSSGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKCSGKGNSKKGLSKSKTHDGLSEADHGLEDIVSEGTGLSLPLPESSCQLLSSQSAHGSLEIGSRCKISVAGTTEKVPFVTKPKKGLKGFFSSIRRHRKSKVSGAEQSDPGAKEPEGARARLYEHVSSALLPHTEQTLQAPREENTKSQDPPGPKVSSLSEPSPTATEKTACKDPEKNTKACASALLQPKPALEASSPEEPHSPETGEKVVAEEVNPPGGPVGDQLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEEEVELEEEEEEVKEEEDDDLEYMRASAQVYPRPNLNPGYHSTTSPGHHGYMLLDPVRSYPGLAPGDLLTPQSDQQESAPNSDEGYYDSTTPGLEDDSGEALGLVHRDCLPRDSYSGDALYEFYEPDDSLENSPPGDDCLYDLHGHSSEMFDPFLNFDPFSSSRPPGAMETEEERLVTIQKQLLYWELRREQLEAQEAHAREAHAREAYTQETHTREAHAQEAYAREACVREVRAREAQVREVQARQEKPIMEYQKRPLGPSVMGLVEGASGASQTSHKGTTSAFPATESSQPDWRDFRPLEKRFEGTCSKKDQSACLMQLFQSDAMFEPDMQEANFGGSPRRAYPTYSPPEEPEEEEVEKEGNATVSFSQALVEFTSNGNLFSSMSCSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENLEFHNDEDLAASLEAYELGYYQKHAFNNYCSRFYQGLPWGVSSLPRYLGLPGMHPRPPPAAMALNRRSRSLDTAETLELELSNSHLAQGYMESDELHAQQEDSDEEEEEEWGRDSPLSLYTEPPGTYDWPAWAPCPLPVRLGPAWISPSQLDGPSSQSQHGKTACCVSPVAMSMLLSVSGPEPKAPGESKAQLARPSHLPLPMGPCYNLQPKVSQSARARPRDMLLPVDEPSCSFSSGGFSPSPLPQAKPVGITHGIPQLPRVRPEPPEPQSIHCGASTLDLSKERAEEGASLPTIYSSTAMDGNLAE", "length": 1108, "header": "tr|A0A5K1UCI1-1|A0A5K1UCI1_PIG Isoform 1 of APC membrane recruitment protein 1 OS=Sus scrofa OX=9823 GN=AMER1 PE=3 SV=1 CANONICAL=A0A5K1UCI1-1" }, "isoforms": [ { "isoform_ac": "A0A5K1UCI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1/entry#A0A5K1UCI1-1", "sequence": { "sequence": "METRKDESPQAKGAAVSVDTQDQGAENGAKNKAAEMIEGPASEPPSSGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKCSGKGNSKKGLSKSKTHDGLSEADHGLEDIVSEGTGLSLPLPESSCQLLSSQSAHGSLEIGSRCKISVAGTTEKVPFVTKPKKGLKGFFSSIRRHRKSKVSGAEQSDPGAKEPEGARARLYEHVSSALLPHTEQTLQAPREENTKSQDPPGPKVSSLSEPSPTATEKTACKDPEKNTKACASALLQPKPALEASSPEEPHSPETGEKVVAEEVNPPGGPVGDQLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEEEVELEEEEEEVKEEEDDDLEYMRASAQVYPRPNLNPGYHSTTSPGHHGYMLLDPVRSYPGLAPGDLLTPQSDQQESAPNSDEGYYDSTTPGLEDDSGEALGLVHRDCLPRDSYSGDALYEFYEPDDSLENSPPGDDCLYDLHGHSSEMFDPFLNFDPFSSSRPPGAMETEEERLVTIQKQLLYWELRREQLEAQEAHAREAHAREAYTQETHTREAHAQEAYAREACVREVRAREAQVREVQARQEKPIMEYQKRPLGPSVMGLVEGASGASQTSHKGTTSAFPATESSQPDWRDFRPLEKRFEGTCSKKDQSACLMQLFQSDAMFEPDMQEANFGGSPRRAYPTYSPPEEPEEEEVEKEGNATVSFSQALVEFTSNGNLFSSMSCSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENLEFHNDEDLAASLEAYELGYYQKHAFNNYCSRFYQGLPWGVSSLPRYLGLPGMHPRPPPAAMALNRRSRSLDTAETLELELSNSHLAQGYMESDELHAQQEDSDEEEEEEWGRDSPLSLYTEPPGTYDWPAWAPCPLPVRLGPAWISPSQLDGPSSQSQHGKTACCVSPVAMSMLLSVSGPEPKAPGESKAQLARPSHLPLPMGPCYNLQPKVSQSARARPRDMLLPVDEPSCSFSSGGFSPSPLPQAKPVGITHGIPQLPRVRPEPPEPQSIHCGASTLDLSKERAEEGASLPTIYSSTAMDGNLAE", "length": 1108, "header": "tr|A0A5K1UCI1-1|A0A5K1UCI1_PIG Isoform 1 of APC membrane recruitment protein 1 OS=Sus scrofa OX=9823 GN=AMER1 PE=3 SV=1 CANONICAL=A0A5K1UCI1-1" }, "locus": { "chromosome": "X", "start_pos": 50852630, "end_pos": 50849307, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033964.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033964.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029629.2", "url": "https://www.ensembl.org/id/ENSSSCP00000029629.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512031", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512031", "resource": "KEGG Pathway" }, { "id": "R-SSC-195253", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-195253", "resource": "Reactome", "description": "Degradation of beta-catenin by the destruction complex" }, { "id": "R-SSC-196299", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-196299", "resource": "Reactome", "description": "Beta-catenin phosphorylation cascade" }, { "id": "R-SSC-4641262", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4641262", "resource": "Reactome", "description": "Disassembly of the destruction complex and recruitment of AXIN to the membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YLZ2-1", "protein_name": "APC membrane recruitment protein 1", "gene_name": "AMER1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "METGCTEEAARTQSQSAACRQCKGGEQQPEENVERLSQRSDASATAAEQQQPQAPSGKLKKTAFKLFGGKRSICTLPSFFSSRNKGQGKGASKKGLSKSKTHDGISGTAYDEGSGVQLESPSDGSRDSHPCLLPSSQSVHVAIDTSVKFDFGRQDGSPPGSIEGYEKKPNGDKSSFPRPKKGLKGLLNSIRRHRKSKVAECEKTELSEWPGDSEETSKAQGTKAETPGAVEEGGPGSVPLAAACPGSSEDNCLVRTVADFGEAAEPDWLQADKGSCEGDVVAVPGGKDDLDAKSEVDAVVYTESNYSHLPVALHPDLADNDPPSLHSGDQLSLLFGDVTSLKSFDSLTGCGDIIAEPDILSIAESTISVERSRDTAKRSPCLVTYQGGGEEMAMSEEEYLQQIWDSTAEEGRSYEAPLPPVVSSPELQAVSSKLETCGLHEGEVHPYASGAVDGVEILTPQSDQQESAPNSDEGYYDSTTPGPEDETGDGLCEIKKDRLPRDSYSGDALYEFYEPDDTLMSPSHGEQSLFESKVSHPEIFSYFLDFCLPPEKSLIQMMDQKRGVMETEEERLAAIQKELLFWELQREPGLKRLDVPSKEKCPREKQHVECNTRAANLIGKSQSCLGSEQIASQALNRSVNGGILVARAENPEWSDFPGPLCPENCYNSQKAQGSCLIQLMKNNPGFDSDPDCALFGGSLHGSAALAKPGMFPSRRPLEHEGCLQSEHHSGVEAAGREPQADSECEPEHAMSFSQALVEFTSSGTLFSSLSESLGSSDSGSSFTQNLPVLPTMVTFDIVDVEQEGEGECEQHLEMNADEDMAASFEAFDESYVQKESFAECDERMFLGYPQGSFQSCNWGVASLPRHLHLHGLSPAMPAPLSLNRRSRSLDTESLEFELADLQVSKNGLKPCQLWSKWDKKYSDGARRSRSKEEAELSAPEGGETNGVLSWPGLQHLQYDAELAPGGIKHWGFAPAAGMPSSWEPSERSDADPPFFPLSRSCARETLERQPQDPEPNRLLVRPSNLPLQPDTRQPQEASGSYRYHGEAPAKKLARVLPLGEPEPPQSISFAQSPEKPAKCKPVGVTQGMPQCHDSDDTETLKSSACFAERYGSASKELLKARAAPGNVLPSGCLNTAVNCDPPLSNTIHDAKCGSSPSA", "length": 1158 }, "evidence": [ { "id": "A0A5K1UCI1", "url": "https://omabrowser.org/oma/group/A0A5K1UCI1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZCP6-1", "protein_name": "APC membrane recruitment protein 1", "gene_name": "Amer1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEIQQDETVQIKRTSTSSDAQDQGAEKGAKNKTAETTEGSTSEPPLSGPGRLKKTALKLFGGKKGICTLPSFFGGGRSKGSGKGSSKKGLNKSKTHDGLSESSHGPEDVVVEETELSTPLSKSPSQFPSSQSAHGALEIGSRHKTSVTEAVEKAGVEKVPSVHKPKKGLKGFLNSIRRHRKSKVSGADQSGLGAKELEGTRTMSQEHVSSISLPSSEEIFRDAIKENTKPQDAPGPKMSPAREHFSLTTEKTACKNPEKLTMTCASEFMQPKPILEASSLEEPHTSETEGKVVTGDANPPNGPVGDQLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDNEEEEEEDEEVELEDEEEEVKDGEEDDDLEYLWASAQIYPRFNMNLGYHTAISPSHQGYMLLDPVQSYPNLGLGELLTPQSDQQESAPNSDEGYYDSTTPGFEDDSGEALGLVHRDCLPRDSYSGDALYEFYEPDDSLEHSPPGDDCLYDLRGRNSEMLDPFLNLEPFSSRPPGAMETEEERLVTIQKQLLYWELRREQREAQEACAREAHAREAYSRDTHTRESYGKNTRARETQALEVHSQEGRVQETKVRQEKPALEYQMRPLGPSVMGLVPGTPGGSQTSHRGTTSAFPATSSSEPDWRDFRPLEKRFEGTCSKKDQSTCLMQLFQSDAMFEPDMQEANFGGSPRKAYPSYSPPEEPEEEEDENEGNATVSFSQALVEFTSNGNLFTSMSYSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENPEFNNDEDLTASLEAFELGYYHKHAFNSYHSRFYQGLPWGVSSLPRYLGLPGVHPRPPPAAMALNRRSRSLDNAETLELELSSSHLAQGYVESDELQDHQEDSDEEGEEEEGEWGRDSPLSLYTEPPGVYDWPPWAHCPVPVGPGLAWLSPNQLDEPFNQSSYVQATCCVPPVAMSVPGRAPGDSVSQPARPSHLPLPMGPCYNLQSQASQSGRARPRDVLLPVDEPSCSSISGANSLSQAKPVGITHGIPQLPRVRPEPLQLQPNHYRASNLDLSKERGEQGASLSTSYSSTAMNGNLAK", "length": 1111 }, "evidence": [ { "id": "A0A5K1UCI1", "url": "https://omabrowser.org/oma/group/A0A5K1UCI1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RDM5-1", "protein_name": "APC membrane recruitment protein 1", "gene_name": "amer1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEIATRCEVGAMRGPSSDSVSHDIPQPQSPPSVKIRKTAFKFFGGRKSICVLPSFFGGRGRSQRKGSSKTGVTKSQTYDGVSRACWDDLGRSSSEVASGDFEFCSEPQKSQEDHGKSQSLPRQRRGLRGLFSSIRRHRKNKNVEVEKREALEMSSSFHAKTVPGALPSVSDRGDYHGDSQGEELVPDVPNQTTGSECELPLAATECTIDVTLVPEKRRSRVEMDKRRRAEEEGIGEDEKTGRQEGLMTYHQPLSAESELDRLAEQNVDVPDGEPPVASCSSENLVFGDVSSLKSFDSLTGCGDIIADQDDVSVAESSVSADRGSRNAGKRSSCFVTYQGGGEEMATPDEIDADYLQSLWESETSNEVCYIPSDRGSDSPSLTPDQQLSSIRATSSSSPMGITETALTPADLLSPQSDRQESVPNSDEGYYDSTTPGMEEESRERPHQERLPRDSYSGDALYELFEPDDRLLSPSLPPKDAHSFVGAPLQADKSPTNPLYSLASTAIETGAMETEEERLSKIQHALLCCELQNLRSPSKNQLLFHSDCFYDDSNLPVDDSKQDLQEVINQRYPQSPPRSQAVKEGVPRIRGQVQESSLFAPCADSVLNPQVIETTRPQPQSDDQGSLRPSRGCSQSQEELMVCFSQALVDFTKNTRLYRNSTESLDGSESSSPFGPSLRALPAIVTFDVVDMENEGECEQQTDLAEEEEELASPYEPFEDDGCYLQQDAFAECDQRTFDAYEQSLLLSNAWGIASLPRHLSLGRPCPPVPAPLALNRRSRSLDTDSLEFQTSEIYTSVTKYDSKGTAFSQSRTVDCNDMDFPRQPCRITVDSWRRGYRQNFDSSNASQQELKLPHLSQSTVRPSHLPLKNNCRSRNLPAATRVDGEGEILFGGGDALYPCSYPPMGTQWKNRPVGVTQGVPHLRSEQSADH", "length": 930 }, "evidence": [ { "id": "A0A5K1UCI1", "url": "https://omabrowser.org/oma/group/A0A5K1UCI1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5JTC6-1", "protein_name": "APC membrane recruitment protein 1", "gene_name": "AMER1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METQKDEAAQAKGAAASGSTREQTAEKGAKNKAAEATEGPTSEPSSSGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKGSGKGSSKKGLSKSKTHDGLSEAAHGPEDVVSEGTGFSLPLPELPCQFPSSQSAHGALETGSRCKTSVAGATEKAVAEKFPSMPKPKKGLKGFFSSIRRHRKSKVTGAEQSEPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVSPTPEPSPPATEKMACKDPEKPMEACASAHVQPKPAPEASSLEEPHSPETGEKVVAGEVNPPNGPVGDPLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGYHPTTSPGHHGYMLLDPVRSYPGLAPGELLTPQSDQQESAPNSDEGYYDSTTPGFEDDSGEALGLVRRDCLPRDSYSGDALYEFYEPDDSLENSPPGDDCLYDLHGRSSEMFDPFLNFEPFLSSRPPGAMETEEERLVTIQKQLLYWELRREQLEAQEARAREAHAREAHAREAYTREAYGREAYAREAHTWEAHGREARTREAQAREVRCRETQVRETQARQEKPVLEYQMRPLGPSVMGLAAGVSGTSQISHRGITSAFPTTASSEPDWRDFRPLEKRYEGTCSKKDQSTCLMQLFQSDAMFEPDMQEANFGGSPRRAYPTYSPPEDPEEEEVEKEGNATVSFSQALVEFTSNGNLFSSMSCSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENPEFHNDEDLAASLEAFELGYYHKHAFNNYHSRFYQGLPWGVSSLPRYLGLPGLHPRPPPAAMALNRRSRSLDTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSPLSLYTEPPGAYDWPAWAPCPLPVGPGPAWISPNQLDRPSSQSPYRQATCCIPPMTMSISLSVPESRAPGESGPQLARPSHLHLPMGPCYNLQPQASQSMRARPRDVLLPVDEPSCSSSSGGFSPSPLPQAKPVGITHGIPQLPRVRPEHPQPQPTHYGPSSLDLSKERAEQGASLATSYSSTAMNGNLAK", "length": 1135 }, "evidence": [ { "id": "A0A5K1UCI1", "url": "https://omabrowser.org/oma/group/A0A5K1UCI1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TS75-1", "protein_name": "APC membrane recruitment protein 1", "gene_name": "Amer1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESQQDEAVQTKGASTSSDAQDQGAEKGAKNKTTEATEGPTSEPPLSGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKGSGKVSSKKSLNKSKTHDGLSEASQGPEDVVIEETDLSTPLSKSSAQFPSSQSANGALEIGSKHKTSGTEAIEKAGVEKVPSVHKPKKSLKSFFSSIRRHRKGKTSGADQSVPGAKELEGARTRSHEHVSSISLPSSEEIFRDTRKENAKPQDAPGPKMSPAQVHFSPTTEKAACKNPEKLTRTCASEFMQPKPVLEGGSLEEPHTSETEGKVVAGEVNPPNGPVGDQLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDNDDEEEEEEEEEEEEEEEEEEEEEEEEEEEELLEDEEEVKDGEENDDLEYLWASAQIYPRFNMNLGYHTAISPSHQGYMLLDPVQSYPNLGLGELLTPQSDQQESAPNSDEGYYDSTTPGFEDDSGEALGLAHRDCLPRDSYSGDALYEFYEPDDSLEHSPPGDDCLYDLRGRNSEMLDPFLNLEPFSSRPPGAMETEEERLVTIQKQLLYWELRREQREAQEACAREAHAREAYARDTHTRESYGRNVRARETQALEAHSQEGRVQETKVRQEKPALEYQMRPLGPSVMGLVAGTSGGSQTSHRGTTSAFPATSSSEPDWRDFRPLEKRFEGTCSKKDQSTCLMQLFQSDAMFEPDMQEANFGGSPRKAYPSYSPPEEPEEEEEEKEGNATVSFSQALVEFTSNGNLFTSMSYSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENPEFNNDEDLTASLEAFELGYYHKHAFNSYHSRFYQGLPWGVSSLPRYLGLPGVHPRPPPAAMALNRRSRSLDNAESLELELSSSHLAQGYMESDELQAHQEDSDEEGEEEEGEWGRDSPLSLYTEPPGVYDWPPWAHCPLPVGPGLAWMSPNQLYEPFNQSSYVQATCCVPPVAMPVSVPGRTPGDSVSQLARPSHLPLPMGPCYNLQSQASQSGRAKPRDVLLPVDEPSCSSISGANSQSQAKPVGITHGIPQLPRVRPEPFQLQPNHYRASNLDLSKERGEQGASLSTSYSSTAMNGNLAK", "length": 1132 }, "evidence": [ { "id": "A0A5K1UCI1", "url": "https://omabrowser.org/oma/group/A0A5K1UCI1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "pmid": "" }, { "name": "beta-catenin destruction complex binding", "id": "GO:1904713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904713", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UCI1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UCI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1UCI1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1108, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1UCI1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1UCI1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 739, "end_pos": 741 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1UET6-1", "uniprot_ac": "A0A5K1UET6", "uniprot_id": "A0A5K1UET6_PIG", "mass": { "chemical_mass": 62638.0, "monoisotopic_mass": 62638.0 }, "refseq": {}, "gene_names": [ { "name": "MARVELD2", "type": "recommended", "evidence": [ { "id": "A0A5K1UET6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ] } ], "protein_names": [ { "name": "MARVEL domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A5K1UET6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MARVELD2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6", "locus": { "chromosome": "16", "start_pos": 47563482, "end_pos": 47530068, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016959", "url": "https://www.ensembl.org/id/ENSSSCG00000016959" } ] } } ], "crossref": [ { "id": "A0A5K1UET6", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1UET6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016959", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016959", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100516404", "url": "https://www.ncbi.nlm.nih.gov/gene/100516404", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516404", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516404", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LLDSTWW", "url": "https://omabrowser.org/oma/group/LLDSTWW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1SKR8", "url": "https://www.orthodb.org/?gene=F1SKR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23288:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07303", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07303", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UET6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SKR8", "url": "https://www.uniprot.org/uniprotkb/F1SKR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SKR8-1", "url": "https://www.uniprot.org/uniprotkb/F1SKR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSNDGRPRNRDRHHDEVPREVDSRDGTVRTFQTLHNSELAVSADPLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPESWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPASPARANHHSPRNSCEDPHGGSLGSCASRKEAEAMFPHDPYGSLGRHTHTARTYSEKVEEYHLRYSYMKSWAGLLRILGVAELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGAAGVGGLGSMYGGYYYSGPKTPFVLVVAGLAWVTTIIILVLGMSMYYRTILLDSNWWPLTEFGINVSLFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAAFCRVEGGQIAAMIFLFVTMIVYLIGALVCLKLWRHEAARRHREYMEQQECDLATACDRQRDQEVHCKELRATKMKPELLSGHIPPGHIPKPIVMPDYVAKYPMIQTDDERERYKAVFQDQFSEYKELSAEVQAVLKKFDELDAMMSRLPHRSENQQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDIQGYS", "length": 547, "header": "tr|A0A5K1UET6-1|A0A5K1UET6_PIG Isoform 1 of MARVEL domain containing 2 OS=Sus scrofa OX=9823 GN=MARVELD2 PE=3 SV=1 CANONICAL=A0A5K1UET6-1" }, "isoforms": [ { "isoform_ac": "A0A5K1UET6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6/entry#A0A5K1UET6-1", "sequence": { "sequence": "MSSNDGRPRNRDRHHDEVPREVDSRDGTVRTFQTLHNSELAVSADPLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPESWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPASPARANHHSPRNSCEDPHGGSLGSCASRKEAEAMFPHDPYGSLGRHTHTARTYSEKVEEYHLRYSYMKSWAGLLRILGVAELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGAAGVGGLGSMYGGYYYSGPKTPFVLVVAGLAWVTTIIILVLGMSMYYRTILLDSNWWPLTEFGINVSLFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAAFCRVEGGQIAAMIFLFVTMIVYLIGALVCLKLWRHEAARRHREYMEQQECDLATACDRQRDQEVHCKELRATKMKPELLSGHIPPGHIPKPIVMPDYVAKYPMIQTDDERERYKAVFQDQFSEYKELSAEVQAVLKKFDELDAMMSRLPHRSENQQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDIQGYS", "length": 547, "header": "tr|A0A5K1UET6-1|A0A5K1UET6_PIG Isoform 1 of MARVEL domain containing 2 OS=Sus scrofa OX=9823 GN=MARVELD2 PE=3 SV=1 CANONICAL=A0A5K1UET6-1" }, "locus": { "chromosome": "16", "start_pos": 47561305, "end_pos": 47534374, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028212.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028212.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019478.3", "url": "https://www.ensembl.org/id/ENSSSCP00000019478.3" } ] } }, { "isoform_ac": "F1SKR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6/entry#F1SKR8-1", "sequence": { "sequence": "MSSNDGRPRNRDRHHDEVPREVDSRDGTVRTFQTLHNSELAVSADPLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPESWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPASPARANHHSPRNSCEDPHGGSLGSCASRKEAEAMFPHDPYGSLGRHTHTARTYSEKVEEYHLRYSYMKSWAGLLRILGVAELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGAAGVGGLGSMYGGYYYSGPKTPFVLVVAGLAWVTTIIILVLGMSMYYRTILLDSNWWPLTEFGINVSLFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAAFCRVEGGQIAAMIFLFVTMIVYLIGALVCLKLWRHEAARRHREYMEQQEISEPSLLMKRKMCDLATACDRQRDQEVHCKELRATKMKPELLSGHIPPGHIPKPIVMPDYVAKYPMIQTDDERERYKAVFQDQFSEYKELSAEVQAVLKKFDELDAMMSRLPHRSENQQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDIQGYS", "length": 559, "header": "tr|F1SKR8-1|F1SKR8_PIG Computationally mapped isoform of MARVEL domain containing 2 OS=Sus scrofa OX=9823 GN=MARVELD2 PE=3 SV=3 CANONICAL=A0A5K1UET6-1" }, "locus": { "chromosome": "16", "start_pos": 47561305, "end_pos": 47534374, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018468.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018468.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017968.3", "url": "https://www.ensembl.org/id/ENSSSCP00000017968.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516404", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516404", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QNU3-1", "protein_name": "MARVEL domain-containing protein 2", "gene_name": "Marveld2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSDGRSRIQDRGYSEVPRDMPGPDGTLQTLQSLHSSELAVSSDPLPPPPLPLQPPFGPTFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSNIRYISDGVECSPPASPARPNHLPPSSYKDPSGGSEGTFNSPQEAHAMFPQGSYASLDRRTQTALTYSEKVEEYNLRYAYMKSWAGLLRILGVAELLLGAGVFACVTAYIHKDNEWYNLFGYTQPYGTASLGSLGSTYGGYYYSGPKTPFILVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGVNVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPINAGFCRVEGGQIAAMIFLFVTMIVYLVSALVCLKLWRHEAARRHREYMEQQEIKEPSLSSKRRMCEVAPSDRQRDQEVNFKELRTTKMTPELLSGHIPPGYIPKPIVMPDYVAKYPVIRTDDDRERYKAVFQDQFSEYKELSAEVQAILRKFDELDAVMSRLPRHSENFQEHERISRIHEEFRKKKNDPSFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDTQGYS", "length": 557 }, "evidence": [ { "id": "A0A5K1UET6", "url": "https://omabrowser.org/oma/group/A0A5K1UET6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0Y5U6-1", "protein_name": "MARVEL domain containing 2", "gene_name": "MARVELD2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRSAVSSPSGAAAAPFPPPPLPLQPPFGPDAGPGGGQAELKPVRRFIPDSWKNFFRGRRGRASGWDSATSDIRYVSDGTPCSPPASPGPPRVRPGCSGEGCAGSGGSCRSQEAEAMLRGDSLGAPTGMTYSEQVEAYRQRYAYMKSWAGLLRLLGVAELLLGAAVFACVTAYVHKDNEWYNTFGYSQPYGYGTGAAYGGYYYSGPKTPFILVVAGVAWIVTIVLLVLGMSMYYRTILLDSSWWPLTEFGINVAMFLLYMSAAIVYVNDINRGGLCYYQLFKTPINASFCRVEGGQTAAIIFLFVTVLIYLISALVSLKLWRHEAARRHREQMEQEMKTQLSLPDKKYTDSDDTPREEVTYRQLKSMERKPELLNGHIPAGHIPKPIVMPDYLAKYPAIQTNEMRDRYKAVFNDQFAEYKELSVEVHAVLKKFNELEALMRQLPHHPGSIYEQERISKVLQEYEKKKNDPAFLEKKERCEYLKNKLSHIKQRIQDYDKVMNWKVQI", "length": 506 }, "evidence": [ { "id": "A0A5K1UET6", "url": "https://omabrowser.org/oma/group/A0A5K1UET6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1QIE2-1", "protein_name": "MARVEL domain-containing protein 2", "gene_name": "marveld2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHHYNDAPAGSLASLHSLVEHRADSLYSEPFPPPPLPDQPPIGPEFDPSGSEDNGDSAIDIKPVHRFIPDSWKNLFRSSSGSSKLKSMLGSSSKNTTTDGVRCSPPHSPSVPGSYRDPYGGSGGSYNSRKEREAMLLGNPVESIDGRTAHTALTYSEKVEEYNQRYAYMKSWAGLLRILGCVELLLGAAIFACVCAYIHKDNEWYNTFGYSQPGGFYGGGYGGYGGSYGSGYGNANYSGPKTPFILVVAGLAWIVTIIMLVLGMTMYYQTILLDSSWWPLTEFVINLALALLFLAAGCVYVNDTLRGGLCYYPVFNNGINGAFCRTEAGQTAAIIFLFFTMIVYLVGAIVCLKLWRHEAARRLRERHGQEMQPRDSPAAVHLVVDGSREPVSVLAPVQKTHTAVSNPKVVKGHIPAGHTPKPVIMPDYVAKYPAIRTDEQRDQYKAVFNDQYSEYKELHVEVQAVLKKFDEMDVMMQNLPQNPTSYTERDRINKILQDYQKKKMDPSFLEKKERCEYLKNKLSHIKQRIHEYDKVMGWNDGYGLH", "length": 545 }, "evidence": [ { "id": "A0A5K1UET6", "url": "https://omabrowser.org/oma/group/A0A5K1UET6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3UZP0-1", "protein_name": "MARVEL domain-containing protein 2", "gene_name": "Marveld2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSSDARSRIRDRGYSEVPRDTSCPDGTIRTFQSLHSSELAVSADPLPPPPLPLQPPFGPSFYSSDTEEPAVAPDLKPVRRFVPDSWKNFFRGKKKDPEWDNPVSDIRYISDGVECSPPASPARANHHPYKDPSRGSQGTFNSQHEADAMFAHDPYASLDRRTQTARTYSEKVEEYNLRYAYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDNEWYNLFGYTQPYGMGGLGSLGNTYGGYYYSGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGVNVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPMNAMFCRVEGGQIAAMIFLFVTMIVYLVSALVCLKLWRHEAARRHREFLEQQEINDPSLSSKRKMCEAAISDRQRDQEVNVKDLRTTTKMTPELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDDRERYKAVFQDQFSEYKELSAEVQAILRKFDELDTVMSRLPHHSENRQEHERISRIHEEFRKKKNDPSFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDTQGYP", "length": 555 }, "evidence": [ { "id": "A0A5K1UET6", "url": "https://omabrowser.org/oma/group/A0A5K1UET6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N4S9-1", "protein_name": "MARVEL domain-containing protein 2", "gene_name": "MARVELD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPTLHDSERAVSADPLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPASPARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYNLRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLGSMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDKVMNWDVQGYS", "length": 558 }, "evidence": [ { "id": "A0A5K1UET6", "url": "https://omabrowser.org/oma/group/A0A5K1UET6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ], "pmid": "" }, { "name": "Schmidt-Lanterman incisure", "id": "GO:0043220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043220", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ], "pmid": "" }, { "name": "paranodal junction", "id": "GO:0033010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033010", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ], "pmid": "" }, { "name": "tricellular tight junction", "id": "GO:0061689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061689", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "establishment of endothelial barrier", "id": "GO:0061028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061028", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ], "pmid": "" }, { "name": "bicellular tight junction assembly", "id": "GO:0070830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070830", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UET6", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1UET6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 547, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1UET6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1UET6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1UET6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 189, "end_pos": 368, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5K1UET6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UET6" }, { "id": "PS51980", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51980" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OCEL", "eco_id": "ECO_0000259", "start_pos": 429, "end_pos": 540, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 }, { "start_pos": 314, "end_pos": 316 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1UN68-1", "uniprot_ac": "A0A5K1UN68", "uniprot_id": "A0A5K1UN68_PIG", "mass": { "chemical_mass": 21999.0, "monoisotopic_mass": 21999.0 }, "refseq": {}, "gene_names": [ { "name": "IL28B", "type": "recommended", "evidence": [ { "id": "A0A5K1UN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68" } ] }, { "name": "LOC110255217", "type": "synonym", "evidence": [ { "id": "A0A5K1UN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68" } ] } ], "protein_names": [ { "name": "Interleukin 28B (interferon, lambda 3)", "type": "synonym", "evidence": [ { "id": "A0A5K1UN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UN68", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IL28B", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68", "locus": { "chromosome": "6", "start_pos": 47953467, "end_pos": 47951595, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000057240", "url": "https://www.ensembl.org/id/ENSSSCG00000057240" } ] } } ], "crossref": [ { "id": "ENSSSCG00000035185", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035185", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31943", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31943", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31943:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31943:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8854691", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854691", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5K1UN68", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UN68-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RKLDMALGGSLVLVLVLMTVAPPRTGAVPVPEALRALPGARGCHLAQFKSLSPQALQAFKRAKDAFEESLLEDWNCSSRIFPRSRDLKQLQVWERPVALEAEVALTLSVLGSLANSSLHSSLDQPLHTLRHIHAQLQACVPAQPMAGPRPRGRLHHWLHRLQEAQKKEPQSCLEASVMFNLFRLLTRDLKCVASGDLCV", "length": 199, "header": "tr|A0A5K1UN68-1|A0A5K1UN68_PIG Isoform 1 of Interleukin 28B (interferon, lambda 3) OS=Sus scrofa OX=9823 GN=IL28B PE=3 SV=1 CANONICAL=A0A5K1UN68-1" }, "isoforms": [ { "isoform_ac": "A0A5K1UN68-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68/entry#A0A5K1UN68-1", "sequence": { "sequence": "RKLDMALGGSLVLVLVLMTVAPPRTGAVPVPEALRALPGARGCHLAQFKSLSPQALQAFKRAKDAFEESLLEDWNCSSRIFPRSRDLKQLQVWERPVALEAEVALTLSVLGSLANSSLHSSLDQPLHTLRHIHAQLQACVPAQPMAGPRPRGRLHHWLHRLQEAQKKEPQSCLEASVMFNLFRLLTRDLKCVASGDLCV", "length": 199, "header": "tr|A0A5K1UN68-1|A0A5K1UN68_PIG Isoform 1 of Interleukin 28B (interferon, lambda 3) OS=Sus scrofa OX=9823 GN=IL28B PE=3 SV=1 CANONICAL=A0A5K1UN68-1" }, "locus": { "chromosome": "6", "start_pos": 47941385, "end_pos": 47939900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011718.6", "url": "https://www.ensembl.org/id/ENSSSCT00000011718.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011416.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011416.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UN68", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8854691", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854691", "resource": "Reactome", "description": "Interleukin-20 family signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UN68", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68" } ], "pmid": "" }, { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UN68", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UN68", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UN68", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UN68", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68" } ], "pmid": "" }, { "name": "positive regulation of immune response", "id": "GO:0050778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050778", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UN68", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UN68", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UN68" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1UXY4-1", "uniprot_ac": "A0A5K1UXY4", "uniprot_id": "A0A5K1UXY4_PIG", "mass": { "chemical_mass": 25762.0, "monoisotopic_mass": 25762.0 }, "refseq": {}, "gene_names": [ { "name": "OAZ1", "type": "recommended", "evidence": [ { "id": "A0A5K1UXY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4" } ] } ], "protein_names": [ { "name": "Ornithine decarboxylase antizyme 1", "type": "recommended", "evidence": [ { "id": "A0A5K1UXY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome. Triggers ODC degradation by inducing the exposure of a cryptic proteasome-interacting surface of ODC. Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UXY4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4#function" }, { "database": "UniProtKB", "id": "ARBA00046121", "url": "https://www.uniprot.org/uniprotkb/ARBA00046121#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UXY4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OAZ1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4", "locus": { "chromosome": "2", "start_pos": 76293150, "end_pos": 76296620, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013460", "url": "https://www.ensembl.org/id/ENSSSCG00000013460" } ] } } ], "crossref": [ { "id": "A0A5K1UXY4", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1UXY4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013460", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013460", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10279", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10279", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10279:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10279:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02100", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02100", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-350562", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-350562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-351202", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-351202", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5K1UXY4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UXY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "NPPCSGSSTATASPERRRGINPAPPSTPPAPCRSSACTAAEAAAARVGLLPVLLTSPFPSVPGSPSTAVVTWVQGLGGAPDVPHPPLKIPGGRGNSQRDHNLSANLFYSDNRLNVTEELTSNNKTRILNVQSRLTDAKHINWRAVLSNSCLYIEIPGGALPEGSKDSFAVLLEFAEEQLHADHVFICFHKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMAYTFERESSGEEE", "length": 239, "header": "tr|A0A5K1UXY4-1|A0A5K1UXY4_PIG Isoform 1 of Ornithine decarboxylase antizyme 1 OS=Sus scrofa OX=9823 GN=OAZ1 PE=3 SV=2 CANONICAL=A0A5K1UXY4-1" }, "isoforms": [ { "isoform_ac": "A0A5K1UXY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4/entry#A0A5K1UXY4-1", "sequence": { "sequence": "NPPCSGSSTATASPERRRGINPAPPSTPPAPCRSSACTAAEAAAARVGLLPVLLTSPFPSVPGSPSTAVVTWVQGLGGAPDVPHPPLKIPGGRGNSQRDHNLSANLFYSDNRLNVTEELTSNNKTRILNVQSRLTDAKHINWRAVLSNSCLYIEIPGGALPEGSKDSFAVLLEFAEEQLHADHVFICFHKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMAYTFERESSGEEE", "length": 239, "header": "tr|A0A5K1UXY4-1|A0A5K1UXY4_PIG Isoform 1 of Ornithine decarboxylase antizyme 1 OS=Sus scrofa OX=9823 GN=OAZ1 PE=3 SV=2 CANONICAL=A0A5K1UXY4-1" }, "locus": { "chromosome": "2", "start_pos": 76296539, "end_pos": 76293561, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014704.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014704.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014307.5", "url": "https://www.ensembl.org/id/ENSSSCP00000014307.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 27, "start_aa": "Thr", "end_pos": 27, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr27", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UXY4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-350562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-350562", "resource": "Reactome", "description": "Regulation of ornithine decarboxylase (ODC)" }, { "id": "R-SSC-351202", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-351202", "resource": "Reactome", "description": "Metabolism of polyamines" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UXY4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UXY4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UXY4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4" } ], "pmid": "" }, { "name": "polyamine biosynthetic process", "id": "GO:0006596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006596", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UXY4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4" } ], "pmid": "" }, { "name": "viral translational frameshifting", "id": "GO:0075523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075523", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UXY4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ornithine decarboxylase inhibitor activity", "id": "GO:0008073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008073", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UXY4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UXY4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1UXY4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 239, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1UXY4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1UXY4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 27 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 114, "end_pos": 116 }, { "start_pos": 123, "end_pos": 125 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1UYV7-1", "uniprot_ac": "A0A5K1UYV7", "uniprot_id": "A0A5K1UYV7_PIG", "mass": { "chemical_mass": 156905.0, "monoisotopic_mass": 156905.0 }, "refseq": { "ac": "XP_001927324", "name": "attractin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927324" }, "gene_names": [ { "name": "ATRN", "type": "recommended", "evidence": [ { "id": "A0A5K1UYV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" } ] }, { "name": "ATRN", "type": "synonym", "evidence": [ { "id": "XP_001927324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927324" } ] } ], "protein_names": [ { "name": "Attractin", "type": "recommended", "evidence": [ { "id": "A0A5K1UYV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7/entry#names_and_taxonomy" } ] }, { "name": "attractin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001927324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927324" } ] } ], "function": [ { "annotation": "Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti. Has a critical role in normal myelination in the central nervous system.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UYV7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7#function" }, { "database": "UniProtKB", "id": "ARBA00058400", "url": "https://www.uniprot.org/uniprotkb/ARBA00058400#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UYV7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ATRN", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7", "locus": { "chromosome": "17", "start_pos": 32054249, "end_pos": 32239519, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007153", "url": "https://www.ensembl.org/id/ENSSSCG00000007153" } ] } } ], "crossref": [ { "id": "ENSSSCG00000007153", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007153", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100101470", "url": "https://www.ncbi.nlm.nih.gov/gene/100101470", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056737", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056737", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100101470", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100101470", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNGCPSD", "url": "https://omabrowser.org/oma/group/MNGCPSD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46376:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46376:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24972", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24972", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001927324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927324", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5K1UYV7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UYV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAAAAATEAKLKRRTAETTAPASRNDRRRQDWDTTGAGRPGLGAGLRLSRWLLLLLLPPLLLLPWVAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFITDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDSNETVPEVVATSGYALLHFFSDAAYNLTGFNITYNFDMCPNNCSGRGECKISNSSNTVQCECSENWKGEACDIPHCVNNCGFPHRGICNSSDVRGCSCFSEWQGPGCSVPVPANQSFWTREEYTNLKLPRASHKAVVNGNIMWIVGGYMFNHSDYNMVLAYDLASREWLALNSSVNSVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLTSGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILNTQGALVQGGYGHSSVFDHITRALYVHGGYKAFSANKYRLADDLYRYNVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEECEAHQSEAACLAAGPGIRCVWDTGSSQCVSWELATEAQRAKLNSECFFKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPMNHSCTEGQISIAKYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLSCRNHNAFLASLTTQKKVEFVLKQLRTMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPSSRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGECTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSSCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPSGSSYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCVNQSVCEKCENLTTGRHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLKGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI", "length": 1416, "header": "tr|A0A5K1UYV7-1|A0A5K1UYV7_PIG Isoform 1 of Attractin OS=Sus scrofa OX=9823 GN=ATRN PE=4 SV=1 CANONICAL=A0A5K1UYV7-1" }, "isoforms": [ { "isoform_ac": "A0A5K1UYV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7/entry#A0A5K1UYV7-1", "sequence": { "sequence": "MVAAAAATEAKLKRRTAETTAPASRNDRRRQDWDTTGAGRPGLGAGLRLSRWLLLLLLPPLLLLPWVAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFITDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDSNETVPEVVATSGYALLHFFSDAAYNLTGFNITYNFDMCPNNCSGRGECKISNSSNTVQCECSENWKGEACDIPHCVNNCGFPHRGICNSSDVRGCSCFSEWQGPGCSVPVPANQSFWTREEYTNLKLPRASHKAVVNGNIMWIVGGYMFNHSDYNMVLAYDLASREWLALNSSVNSVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLTSGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILNTQGALVQGGYGHSSVFDHITRALYVHGGYKAFSANKYRLADDLYRYNVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEECEAHQSEAACLAAGPGIRCVWDTGSSQCVSWELATEAQRAKLNSECFFKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPMNHSCTEGQISIAKYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLSCRNHNAFLASLTTQKKVEFVLKQLRTMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPSSRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGECTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSSCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPSGSSYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCVNQSVCEKCENLTTGRHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLKGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI", "length": 1416, "header": "tr|A0A5K1UYV7-1|A0A5K1UYV7_PIG Isoform 1 of Attractin OS=Sus scrofa OX=9823 GN=ATRN PE=4 SV=1 CANONICAL=A0A5K1UYV7-1" }, "locus": { "chromosome": "17", "start_pos": 32239433, "end_pos": 32058487, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035365.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035365.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029393.2", "url": "https://www.ensembl.org/id/ENSSSCP00000029393.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UYV7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100101470", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100101470", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O75882-1", "protein_name": "Attractin", "gene_name": "ATRN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPRLLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAAGPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI", "length": 1429 }, "evidence": [ { "id": "A0A5K1UYV7", "url": "https://omabrowser.org/oma/group/A0A5K1UYV7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99J86-1", "protein_name": "Attractin", "gene_name": "Atrn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVAAAAAAEATEARLRGYTTATAAPAGWKERQHRPCAATGAWRPWPRAGLCLPRVLSRALSPPPLLPLLPLLFSLLLLPLPREAEAAAVAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPTGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNKIMRLRFNHFATECSWDHLYVYDGDSIYAPLIAAFSGLIVPERDGNETAPEVTVTSGYALLHFFSDAAYNLTGFNITYNFDMCPNNCSGRGECKSSNSSSTVECECSENWKGESCDIPHCTDNCGFPHRGICNASDTRGCSCFPHWQGPGCSIPVPANQSFWTREEYSDLKLPRASHKAVVNGNIMWVVGGYMFNHSDYSMVLAYDLASREWLSLNHSVNSVVVRYGHSLALHKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKDQYAVVGHSAHIVTLSSGRVVMLVIFGHCPLYGYISVVQEYDLEKNTWSILQTQGALVQGGYGHSSVYDHRTKALYVHGGYKAFSANKYRLADDLYRYHVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPELHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDVLVFTSEQCDAHRSEAACVAAGPGIRCLWDTQSSRCTSWELATEEQAEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPVNHSCTEGQISIAKYDNCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLSCRNHNAFLASLTSQKKVEFVLKQLRLMQSSQSTSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGECTSSSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSSCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSHASTGNVYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCEDLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGEECQLCEVENRYQGNPLKGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWATSFPAGTQTGEEVPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI", "length": 1432 }, "evidence": [ { "id": "A0A5K1UYV7", "url": "https://omabrowser.org/oma/group/A0A5K1UYV7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VB20-1", "protein_name": "Distracted, isoform C", "gene_name": "dsd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCLAAEPPQKQPNRSSTSPTFNAKYRRKCLLLLTLLLFHGCFSGLHRAAAFNCTAHGGRCQNDGQCQEDGQCLCADGWQGPECQFCGGKVRMYHPMGTIHDGWGNYSVSVKCSWLIDARHPHWNRRHNTNPSRTANIRIHLREFATECGWDHLYIYDGDSVDSPLLAVFSGLMYRGNFSIRRVPQVIATSGTALVHFFSDDAYNMSGFNLTYKMNSCPSDSDEVECSGHGKCRDGDCICDPMYRGEACNIAACPNNCFESKNQGHCRLDQERCSCYEGFAGDDCSQISAHGAWSTVHPKHSPAPAGSASHGATIWRDTLHIVGGESYGRGKLMSTYDFNGNVWETVHPEDGSEVPDKRYGASTVMYGDKIFMYGGVVKGHGISNELWAFDVSARTWANISVRADPSCNATGGTTAMCGPLHVVGHTATLVPGYGDKNNYQYMVVIFGHSPNYGYLNTVQEFNFASREWRIVPTTGYVVKGGYGHSAAYDFLTEKVYVYGGIVSESESSQVLSSRLYAYEPATRVWSLLSAAPSARLLHTANFVNQGLMMVFGGNTHNDTSQSYGAKCYSQDLLVYDVYCDSWHYHPMPGHLQADLARFGHSSVVFEESLYIYGGFNGQLLNDMLRYQPGYCSYYTKQEKCTAARPGVKCIWDVQKMRCIAITQVQRSAIYGREQYDYVACPSKSRLTLTSELLHDVHRCQELASCQSCVSTAFGCTYCGNGVCSKERCRETTSMASVFFESSTQMAVSTASPPLNAKHLDSCPISEEYLVSSVCDQLHNCRACSANLACRWDSEHNRCKSYTSYGGLALNRTQDEVACSPSCASLTNCQNCTEDECIWCQNEQRCVDRNAYTASFPYGQCREWTTFTAKCRSAPIQSTALAVGSTTALSSAQCGYYNSCQMCLDDPACGWCDNGSNTGLGRCVVGGALAPYDDTECALKHWFFTSCPRCNCNGHSYCNDQQHCEQPCNNLTTGAHCEKCRTGYWGNPINGGKCQRCDCNGQGVYCHPDTGKCFCTTKGIVGDHCEKCDSQNHYHGDPLKGSCYYELTIDYQFTFNLSKKEDRHFTQINFRNSPGKPEIDADFTITCSVPAKMDISVKRAGSPDMLILVGVNCSTFRHRFPKTDYQFGHSPDDNSSLTTFYVFVHDFQPPIWIQIAFSQYPKLNLQQFFITFSSCFLLLLLMAAVLWKIKQKYDMFRRRQRLFVEMEQMASRPFSQVLVDIENRESIDLSLTLEGIGHLSKKRKKECPSPIALEPCSGNRAAVLSLLVRLPTGGLSQAPSGQSAGLAVASALVTLGNPRRPSIDQHPKEPKSKRKQSQHPDSCT", "length": 1323 }, "evidence": [ { "id": "A0A5K1UYV7", "url": "https://omabrowser.org/oma/group/A0A5K1UYV7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WU60-1", "protein_name": "Attractin", "gene_name": "Atrn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVAVAAAAATEARLRGSTTATAAPAGRKGRQHRPCTATGAWRPGPRARLCLPRVLSRALPPPPLLPLLFSLLLLPLPREAEAAAVAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPTGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLIAAFSGLIVPERDGNETAPEVTVTSGYALLHFFSDAAYNLTGFNITYNFDMCPNNCSGRGECKSSNSSSAVECECSENWKGESCDIPHCTDNCGFPHRGICNASDTRGCSCFPHWQGPGCSIPVPANQSFWTREEYSDLKLPRASHKAVVNGNIMWVVGGYMFNHSDYSMVLAYDLTSREWLPLNHSVNSVVVRYGHSLALHKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKDQYAVVGHSAHIVTLASGRVVMLVIFGHCPLYGYISVVQEYDLEKNTWSILHTQGALVQGGYGHSSVYDDRTKALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPELHHDVNRFGHSAVLYNSTMYVFGGFNSLLLSDVLVFTSEQCDAHRSEAACVAAGPGIRCLWDTQSSRCTSWELATEEQAEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPVNHSCTEGQISIAKYESCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGNGWHLVGNSCLKITTAKENYDNAKLSCRNHNAFLASLTSQKKVEFVLKQLRLMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGECTSSSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSSCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQASAGNVYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCEDLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLKGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWATSFPAGTQTGEEVPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI", "length": 1428 }, "evidence": [ { "id": "A0A5K1UYV7", "url": "https://omabrowser.org/oma/group/A0A5K1UYV7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UYV7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UYV7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UYV7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UYV7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UYV7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UYV7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1030, "end_pos": 1032, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1041, "end_pos": 1043, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1060, "end_pos": 1062, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1069, "end_pos": 1071, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1185, "end_pos": 1187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1193, "end_pos": 1195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1237, "end_pos": 1239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1246, "end_pos": 1248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 718, "end_pos": 720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 850, "end_pos": 852, "annotation": "n_glycosylation_sequon" }, { "start_pos": 901, "end_pos": 903, "annotation": "n_glycosylation_sequon" }, { "start_pos": 910, "end_pos": 912, "annotation": "n_glycosylation_sequon" }, { "start_pos": 973, "end_pos": 975, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1UYV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 782, "end_pos": 906, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5K1UYV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 235, "start_aa": "Cys", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5K1UYV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 117, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5K1UYV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UYV7" }, { "id": "PS50027", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50027" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin EGF-like", "eco_id": "ECO_0000259", "start_pos": 1050, "end_pos": 1095, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1030, "end_pos": 1032 }, { "start_pos": 1041, "end_pos": 1043 }, { "start_pos": 1060, "end_pos": 1062 }, { "start_pos": 1069, "end_pos": 1071 }, { "start_pos": 1185, "end_pos": 1187 }, { "start_pos": 1193, "end_pos": 1195 }, { "start_pos": 1237, "end_pos": 1239 }, { "start_pos": 1246, "end_pos": 1248 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 224, "end_pos": 226 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 240, "end_pos": 242 }, { "start_pos": 251, "end_pos": 253 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 403, "end_pos": 405 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 610, "end_pos": 612 }, { "start_pos": 718, "end_pos": 720 }, { "start_pos": 850, "end_pos": 852 }, { "start_pos": 901, "end_pos": 903 }, { "start_pos": 910, "end_pos": 912 }, { "start_pos": 973, "end_pos": 975 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1UZ28-1", "uniprot_ac": "A0A5K1UZ28", "uniprot_id": "A0A5K1UZ28_PIG", "mass": { "chemical_mass": 19420.0, "monoisotopic_mass": 19420.0 }, "refseq": {}, "gene_names": [ { "name": "PYY", "type": "recommended", "evidence": [ { "id": "A0A5K1UZ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28" } ] } ], "protein_names": [ { "name": "Peptide YY", "type": "recommended", "evidence": [ { "id": "A0A5K1UZ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28/entry#names_and_taxonomy" } ] }, { "name": "Peptide tyrosine tyrosine", "type": "synonym", "evidence": [ { "id": "A0A5K1UZ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UZ28", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28#function" }, { "database": "UniProtKB", "id": "ARBA00037595", "url": "https://www.uniprot.org/uniprotkb/ARBA00037595#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UZ28", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PYY", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28", "locus": {} } ], "crossref": [ { "id": "A0A5K1UZ28", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1UZ28", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000025414", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000025414", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00126", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00126", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001955", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001955", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10533", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10533", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10533:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10533:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5K1UZ28", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UZ28-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKRAARKSQRTHPTPSAQSLGIKPVPGAQAQQVKIRPGYKPCRESAELRRRLQQSSPWDSSRLPFPDLLSASGAVAMVTVRRPWPAMATVLLGLLICLGTLVDAYPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRYGKRDSPDALLSKLLFPEGEDRPVKSWPEGAYLW", "length": 174, "header": "tr|A0A5K1UZ28-1|A0A5K1UZ28_PIG Isoform 1 of Peptide YY OS=Sus scrofa OX=9823 GN=PYY PE=1 SV=1 CANONICAL=A0A5K1UZ28-1" }, "isoforms": [ { "isoform_ac": "A0A5K1UZ28-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28/entry#A0A5K1UZ28-1", "sequence": { "sequence": "MKKRAARKSQRTHPTPSAQSLGIKPVPGAQAQQVKIRPGYKPCRESAELRRRLQQSSPWDSSRLPFPDLLSASGAVAMVTVRRPWPAMATVLLGLLICLGTLVDAYPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRYGKRDSPDALLSKLLFPEGEDRPVKSWPEGAYLW", "length": 174, "header": "tr|A0A5K1UZ28-1|A0A5K1UZ28_PIG Isoform 1 of Peptide YY OS=Sus scrofa OX=9823 GN=PYY PE=1 SV=1 CANONICAL=A0A5K1UZ28-1" }, "locus": { "chromosome": "12", "start_pos": 19208154, "end_pos": 19192396, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030078.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030078.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023751.3", "url": "https://www.ensembl.org/id/ENSSSCP00000023751.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UZ28", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UZ28", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UZ28", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28" } ], "pmid": "" }, { "name": "feeding behavior", "id": "GO:0007631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007631", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UZ28", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "neuropeptide hormone activity", "id": "GO:0005184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005184", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UZ28", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28" } ], "pmid": "" }, { "name": "neuropeptide Y receptor binding", "id": "GO:0031841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031841", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UZ28", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZ28" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1UZ28-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 174, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1UZ28-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1UZ28" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1V146-1", "uniprot_ac": "A0A5K1V146", "uniprot_id": "A0A5K1V146_PIG", "mass": { "chemical_mass": 129380.0, "monoisotopic_mass": 129380.0 }, "refseq": {}, "gene_names": [ { "name": "STYXL2", "type": "recommended", "evidence": [ { "id": "A0A5K1V146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146" } ] } ], "protein_names": [ { "name": "Serine/threonine/tyrosine interacting like 2", "type": "synonym", "evidence": [ { "id": "A0A5K1V146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V146", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "STYXL2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146", "locus": { "chromosome": "4", "start_pos": 83871436, "end_pos": 83902292, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006311", "url": "https://www.ensembl.org/id/ENSSSCG00000006311" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006311", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006311", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14576", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14576", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100153962", "url": "https://www.ncbi.nlm.nih.gov/gene/100153962", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153962", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153962", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LSMQTNH", "url": "https://omabrowser.org/oma/group/LSMQTNH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5K1V146", "url": "https://www.orthodb.org/?gene=A0A5K1V146", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45682", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45682", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45682:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45682:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5K1V146", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1V146-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATSGDPEEEQVVPSEEDEADVRAVQARYLRSPSPSQYSIVSDAETESIFMDPIHLSSAVAAKQIINEELKPRGIKAEAECPGMLESAEQLLVEDLYNRVREKMDDTSLYNTPCIMDLQRALVQDRQEAPWNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGVYTGPEFYTGLEIQYLGVEVDDFPEVNISQHFRKAAEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVRKKRPIYPNDGFLKQLRELNEKLMEEREEDFGGAGGAEEAEEGEDAGSTVGARVYALTVEEEDDVTSHLSGSSLGKASRASKPPTLIDEEEEEKLYEAWKKGRGLPTGKVPQGRDSRGEEEAEDEDVERIIREWQSRNERYQAEGHRRWDREEEAEEEESDTGSFVRRRRKHTLSESSTSESVSSRDIRVLKQQLEMSSQNRGGRHRSDSVSTESTWDMWNQRLLEIEKEASRRYHSRSKREEVDSSSEVGSGMREDDEQSVSSEASSFYNFCSRNKDKLTALERWKIKRIQFGFHKKDSEAGDGSSEQDAEEVEGEKKNPSDVNLSAYQAWKLKHQKKVGSENKEEVVELSKGEDSALAKKRQRRLELLERSRQTLQESQSMGSWEADSSAASGSIPLSAFWSAAPSVSADGDTASVLSTQSHSSHPSQALRNVGGCLASAPTTPLPNLPVGPGDTISIASIQNWIANVVSETLAQKQNEILLLSRSPSVASMKVAPAASCLGDDQVSMLSGQSSSSLGGSLLPQSQARPSSDTQSVLSSHTTQSSRAEGTGSKVRGTSKPIYSLFADNVDLRELGRKEKEMQMELKEKMSEYKMEKLASDNKRSSLFKKKKGRGDEDDDVGDWDEDTDSAIGSFRYSSRSNSQKPETDTASSLAVSDSYGSGSRAGKEMDSSINKWLSGLRTEEKSPPQSDWSGSSRGKCTRSSLLRETESKSSSYKFSKSQSEEQDTSSYHEANGNSVRSTSKFSASSTREGREMHTFSRSTFSETSSSREESPEPYFFRRTPEPSEGEESPEPRRPNWARPRDWEDVEESSKSDFSEFGAKRKFTQSFMRSEEEGEKERMEKREEGRFASGRRSQYRRSTDREEEEEMDDEAIIAAWRRRQEETRTKLQRRRED", "length": 1153, "header": "tr|A0A5K1V146-1|A0A5K1V146_PIG Isoform 1 of Serine/threonine/tyrosine interacting like 2 OS=Sus scrofa OX=9823 GN=STYXL2 PE=3 SV=1 CANONICAL=A0A5K1V146-1" }, "isoforms": [ { "isoform_ac": "A0A5K1V146-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146/entry#A0A5K1V146-1", "sequence": { "sequence": "MATSGDPEEEQVVPSEEDEADVRAVQARYLRSPSPSQYSIVSDAETESIFMDPIHLSSAVAAKQIINEELKPRGIKAEAECPGMLESAEQLLVEDLYNRVREKMDDTSLYNTPCIMDLQRALVQDRQEAPWNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGVYTGPEFYTGLEIQYLGVEVDDFPEVNISQHFRKAAEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVRKKRPIYPNDGFLKQLRELNEKLMEEREEDFGGAGGAEEAEEGEDAGSTVGARVYALTVEEEDDVTSHLSGSSLGKASRASKPPTLIDEEEEEKLYEAWKKGRGLPTGKVPQGRDSRGEEEAEDEDVERIIREWQSRNERYQAEGHRRWDREEEAEEEESDTGSFVRRRRKHTLSESSTSESVSSRDIRVLKQQLEMSSQNRGGRHRSDSVSTESTWDMWNQRLLEIEKEASRRYHSRSKREEVDSSSEVGSGMREDDEQSVSSEASSFYNFCSRNKDKLTALERWKIKRIQFGFHKKDSEAGDGSSEQDAEEVEGEKKNPSDVNLSAYQAWKLKHQKKVGSENKEEVVELSKGEDSALAKKRQRRLELLERSRQTLQESQSMGSWEADSSAASGSIPLSAFWSAAPSVSADGDTASVLSTQSHSSHPSQALRNVGGCLASAPTTPLPNLPVGPGDTISIASIQNWIANVVSETLAQKQNEILLLSRSPSVASMKVAPAASCLGDDQVSMLSGQSSSSLGGSLLPQSQARPSSDTQSVLSSHTTQSSRAEGTGSKVRGTSKPIYSLFADNVDLRELGRKEKEMQMELKEKMSEYKMEKLASDNKRSSLFKKKKGRGDEDDDVGDWDEDTDSAIGSFRYSSRSNSQKPETDTASSLAVSDSYGSGSRAGKEMDSSINKWLSGLRTEEKSPPQSDWSGSSRGKCTRSSLLRETESKSSSYKFSKSQSEEQDTSSYHEANGNSVRSTSKFSASSTREGREMHTFSRSTFSETSSSREESPEPYFFRRTPEPSEGEESPEPRRPNWARPRDWEDVEESSKSDFSEFGAKRKFTQSFMRSEEEGEKERMEKREEGRFASGRRSQYRRSTDREEEEEMDDEAIIAAWRRRQEETRTKLQRRRED", "length": 1153, "header": "tr|A0A5K1V146-1|A0A5K1V146_PIG Isoform 1 of Serine/threonine/tyrosine interacting like 2 OS=Sus scrofa OX=9823 GN=STYXL2 PE=3 SV=1 CANONICAL=A0A5K1V146-1" }, "locus": { "chromosome": "4", "start_pos": 83901510, "end_pos": 83871670, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006918.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006918.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006730.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006730.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V146", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153962", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153962", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y572-1", "protein_name": "Serine/threonine/tyrosine interacting like 2", "gene_name": "DUSP27", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASGGDSDSEQVVPDEEKDGPDVKAVQAHYLRSPSPSRYSMISDTDTESIFMEPIHLSSAVAAKQIINEELKTKHIKVDAVCPKMLESAQQLMVEDLYNRVKEKIDDTSLFNTPCVMDLQRALVKDRLETPRDAVDEVWPNVFIAEKSVAVNKSRLKRLGITHVLNAAHGTGVYTGPDFYNGLNIQYMGIEVDDFPDMDISKHFHPAAEFLDEALLTYRGKILVSSEMGISRSAVLVAAYLMIYHHMTILEALMTLRKKRAIYPNDGFLKQLRELNEQLLEEREVEPTGDEDVTPSQSPVTHPGTSSRLSEAEDSESVIGPKAHSITVEEEDNSSMLSSFMSSSSVGKASRVSKRSTLISEEEEEQLYEEWRKKQGLPAKESATDHGKRLLAQEGEQYEEDVEQRIHDWQRRNEKYQREGPPREEDGNSSMGGRPYRSGEFSDDESVSSFEIRTLKRQLEASSFSRMRRSRTDSVSSESTWDMWNQRLMEIEKEAVQRYRSKNKNGGERQSPDTRGKERDVDEESVLSDCSSFYNFCQKNKDKLTPLERWKIKRIQFGFHKKDLESSSSSAPSPAEDGSQTGEEGTEGKNLSDVNLSAYQAWKMKRQKKVGSESKEEFVEFAKSEDSASAKKKQRRVELLERSKKILEESQSMCSWETDSTMSGSIPLSAFWASAPSANGAEDAASTLSMKTNHSSLSQTRSSTGATQPNIPLPNLPVGPGDTISMASIQNWIANVVSETIAQKQNEIMMLSRPSSAMASSVMSGDLGRRVDDDKISLLSSQCGSSFSASHLCQQDMHRAESLSVLSCNTSVSARSEGTSSNMKTMQTSKPLYSLFADDVDLKKLSRKEKEIQMEMREKMSDYQIEKVISDNKRSTLFKKKVTKGEENEIEDGVESVTNNYRHPLQADLDRNDTIFTLSSLSANTGALKSEVETDVTKWLSGLKAEKPSSYHDQSENFREKYSRSSKVREMDSETSSYRVSRSQREELDSSSYESKGDSLRTMSRFSSASAKEDKKMYKFTRSRVSETSSGEKSPELHFFSQTPEPSFDSESPGSSTQSRVRSHHVEACEEEAMSDMSEFGAKRKFTQSFSKSEENGKKEAKVEQSEERFASRQFSQYKRSVRKEEEEELDDDAIIAAWRSRLEETTAKLRRRKEE", "length": 1156 }, "evidence": [ { "id": "A0A5K1V146", "url": "https://omabrowser.org/oma/group/A0A5K1V146/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZRM0-1", "protein_name": "Serine/threonine/tyrosine interacting like 2", "gene_name": "Styxl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATSGDTEEEQVVPNEEDEADVRAVQAHYLRSPSPSQYSVVSDAETESIFMEPIHLSSAVAAKQIINEELKPRGLRTDTECPGMLESAEQLLVEDLYNRVREKMDDKSLFNTPCVLDLQRALIQDRQEAPRNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGVYTGPEFYTGLEIQYLGVEVDDFPEVDISQHFRKAAEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVRRKRAIYPNDGFLKQLRELNEKLMEEREEEDDEEEPEEDAGSTLGARVNSLMVEEEDDATSHLSGSSLGKASQVSQPVTLIDEEEEERLYEEWRKGQGFPKAEASQGRKGSCSASSEQDGDDCEDGAVERIIQEWQSRNERYQAKGHKQWNREEDEEEENSYTSRRRRHTLSESSASESVSSHDIRVLKQQLKRTSQSRHDRHRSDSESTESTWDMWNERLVEIEKEAARKYRSKSKREELDADSEAGSRVREDDEESVLSEASSFYNFCSRNKDKLTALERWKVKRIQFGFHKKDSEVVDAGSEDGTEEATGEKNLSDVNLTAYQAWKLKHQKKVGNENKEEVVEMSKGEDTALAKKRQRRLELLERSRQTLEESRSMGSWEGDSSTASRSIPLSAFWSAAPSVSVDGDTASVLSAQSQHSHLSQPASNMPTTPLPNLPVGPGDTISIASIQNWIASVVNETLAQKQNEMLTLSRAPSVASMRAAPAASCLGDDQLSVLSTSLSGCLPPQSQGRPSSDVQSVLSSTSSLTSRAEGSENKVRGTSKPIYSLFADNVNLKELGRKEKEMQMELQEKMSEYKMEKLASDNKRSSLFKKKKAKDDEDISVGDRDEDTDSAIGSFRYSSRSNSQKPETDASSSLAISDHFRNGRSVGNEVGSNINTWLSGLRMEEKSPPQSDWSGSSRGRYSRSSLFRETESKSCSYKFSKSRSQEQDSSFHETDGNTVRNTSRFSSSTTKEGREMHKFSRSTFSETSSSREESPEPYFFRRTPEPSDGEESPELRRPNWTRPRDWEDVEESSKSDFAEFGAKRKFTQSFMRSEEEGEKERTENREEGRFASGRQSQYRRSTNRQEEEEMDDEAIIAAWRKRQEETRTKLQRRRED", "length": 1137 }, "evidence": [ { "id": "A0A5K1V146", "url": "https://omabrowser.org/oma/group/A0A5K1V146/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N062-1", "protein_name": "Serine/threonine/tyrosine interacting like 2", "gene_name": "STYXL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLESAEQLLVEDLYNRVREKMDDTSLYNTPCILDLQRALVQDRQEAPWNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGVYTGPEFYTGLEIQYLGVEVDDFPEVDISQHFRKAAEFLDEALLTYRGKVLVSSEMGVSRSAVLVVAYLMIFHNMAVLEALMTVRKKRAIYPNDGFLKQLRELNEKLMEEREEDFSRECGEEAVEEGEDAGSTVAARVHTLTVEEEDDAASHLSTSSLGRASQASKPLTLIDEEEEERLYEAWKKGQSLPTGKVLQGEDDRFSASSRQGEEPEDEDVERIIREWQSRNERYQAEGHRRWNREEEEEEESNGSSFVRRRRRHTLSESSTSESVSSHDIRVLKQQLQMSSQNRGGRRRSDSMSTESTWDMWDQRLQEIEKEASRKYHSRNKREEVDASSEVGSRAREDDEESVASEASSFYNFCSRNKDKLTALERWKIKRIQFGFHKKDSEAGDGSSEQGAEEVEGEKKNLSDVNLSAYQAWKLKHQKKVGSENKEEVVELSKGDDLALVKKRQRRLELLERSRQTLEESQSMGSWEADSSAASGSIPLSAFWSAAPSVSADGDTASVLSAQSHSSHPSQALSKVGGCLASTPTTPLPNLHVGPGDTISIASIQNWIANVVSETLAQKQNEMLLSPRPLSVVSMKAAPAGSCLGDDQVSMLSGQSSSALGGCLLPQSQARPSSETQSVLSSHTMSARAEGTGSKVKGTSKPIYSLFADNIDLKELGRKEKEMQTELREKMSEYKMEKLASDNKRSSLFKKKKVKEDEDEDDDVGDRDEDTDSAIGSFRYSSRSNSQKPETDTFSSLAVSDGYGSGSRAGREKDNSINKWLSGLRTEEKSPQSDWSGSSREKCTRSSLIRETESKSSSYKFSKSRSEEQDTSSYDETNSNSVKSTSRFSASSTREGREMHTFSRSMFSETSSSREESPEPYFFRRTPEPSEGEESPEPRRPNGTRSRDWEDVEESSKSDFSEFGAKRKFTQSFMRSEEEGEKARMEKKEEGRFASGRQSRYWRSTDREEEEEMDDEAIIAAWRRRQEETRTKLQRRRED", "length": 1075 }, "evidence": [ { "id": "A0A5K1V146", "url": "https://omabrowser.org/oma/group/A0A5K1V146/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QWM2-1", "protein_name": "Serine/threonine/tyrosine-interacting-like protein 2", "gene_name": "styxl2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASSVEDQQLQQEEAESVKDVQSHYLRCPSPSFSMMSDRFSTVSDRFSVISGSEAESIFMEPIHLSSTIAAKKIISEELPPRPARVSSPPDSALEPAQQLMVEDLYSRVQELLDERSLYNTPCVLDIQRALLRDRLEAPLSPVDEVWPNVFIAEKSVAVNKGRLKRLGITHVLNAAHGTGVYTGPLFYSGMNIHYMGIEVDDFPDADISPHFRSCAEFLDDALLTHRGKVLVDSMMGVSRSAVLVAAYLMIFQNMSIMEALLEIRKKRAISPNEGFIKQLRQLNETLMEERDEDDDETLSQCSVIDARGRLEEQESVFGVKADSIMVEEEEDGGGSVISSVASSAAAAALRAGVQCGSQQPNMQQPADQPSLPGQTREDEDGDVDRMILEWQKRNEKYQSEDWWEAQLLCEDEDDGEDKTQRAVRPDDLESVTSEDVRMVKERIGRRPRRAASLAGSTSSCSSYVDLWKQRLQELEEQAAARHRLQDQDTSSETQQKKIDDDVQSILSDSSSMYNFCKKNKENLTPLERWKIKRIQFGWNKKENAENGEQSEAEPAAAPDLEDVNLTAYQTWKLKQQKKHGGEENKEEILQMSRGEDTATARRRQRREEVLERSRRNLQESQSVCGWETESALSSSIPLSAFCAGAFPSASVCGDDSMSVLSGRSSVLSGRSTRSLPPAVLETPAPPTPVLGPNGEQMVNIANIQNWIASVVNETLQQKQTEMLMGASVAPSRAGSVFSAGRGVDDDKSSVLSGLSASTGLSRSRAESVVSVGAKARSVLSAAGRAESVFSAGGASQLSCGSRKSKITTTSVPLYSLFQDQVNLHKLDTMEKEIKSDMRDKMASYEIKKITEDNKRSTLYKKKKPKEDDEDVDIAKSNGLEELEARTCEKPKPKRDYGRSGILNLPASANNPTSSIDEWLEHVRPPSSKPRVYDGDSGPIRMSRPAYEELQEPSGLDFTSRRSSVSVEVDEEEDYSFRFSSRNCADDDLDPELSYSSRRSPSFNGLSESTSFASRRSYSRYEDEERSSFQNHSIKQKSSVYEDSGRTAGSRRDEEEDEEISAFIAQIKQRARARVAEEMEDDEVLTAWRKQEESKSHDHK", "length": 1100 }, "evidence": [ { "id": "A0A5K1V146", "url": "https://omabrowser.org/oma/group/A0A5K1V146/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q148W8-1", "protein_name": "Serine/threonine/tyrosine-interacting-like protein 2", "gene_name": "Styxl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATGGDAEEEQVVPNEEDEADVRAVQARYLRSPSPSQYSVVSEAETESIFMEPIHLSSAVAAKQIINEELKPRGLRTDTECPGMLESAEQLLVEDLYNRVREKMDDRSLFNTPCVLDLQRALTQDRQEAPRNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGVYTGSEFYTGLEIQYLGVEVDDFPEVDISQHFRKAAEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHSMAILEALMTVRRKRAIYPNDGFLKQLRELNEKLMEEREEEDGEEESEEDAGSMLGARVNSLMVEEEDDATSHLSGSSLGKASQVSKPVTLIDDEEEEKKLYEEWRKGQGFPKGEAAQGRKGRSCSMSSAQDGDDCEDEDVERIIQEWQSRNERYQAKGREQWNREEEEEEENSYSSRRRRHTLSESSASESVSSHDIRILKQQLERSTQSRRGRYRSDSESSESTWDMWNERLVEIEKEAARKYRSKSKREELDGDCSEAGGRVREDDEESVLSEASSFYNFCSRNKDKLTPLERWKIKRIQFGFHKKDSEAGDGGSEHGTEEAAAGEKNLSDVNLTAYQAWKLKHQKKVGSENKEEVVEMSKGEDTVLAKKRQRRLELLERSRQTLEESQSMGSWEADSSTASRSIPLSAFSSAAPSVSADGDTASVLSTQSHRSHASNMPATPLPNLPVGPGDTISIASIQNWIANVVNETLAQKQNEMLLLSRPPSVASMKAAPAACGLGGDDQLSVLSTSLSGCLPPPSQGRPSSDVQSVLSSTSSLTSRAEGSGNKVRGTSKPIYSLFADNVDLKELGRKEKEMQMELQEKMSEYKMEKLASDNKRSSLFKKKKAKDDEDMSVGDRDEDTDSAIGSFRYSSRSNSQKPETDASSSLAISDHYRNGRSMGNEMDSNINTWLSGLRMEEKSPPQSDWSGSSRGRYTRSSLLRETESKSCSYKFSKSRSQEQDTSFHEANGDTVRNTSRFSSSTTKEAREMHKFSRSTFSETSSSREESPEPYFFRRTPEPSDGEESPEPRRPNWTRPRDWEDVEESSKSDFAEFGAKRKFTQSFMRSEEEGEKERTENREEGRFASGRQSQYRRSTNQQEEEEMDDEAIIAAWRKRQEETRTKLQRRRED", "length": 1138 }, "evidence": [ { "id": "A0A5K1V146", "url": "https://omabrowser.org/oma/group/A0A5K1V146/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5VZP5-1", "protein_name": "Serine/threonine/tyrosine-interacting-like protein 2", "gene_name": "STYXL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATRKDTEEEQVVPSEEDEANVRAVQAHYLRSPSPSQYSMVSDAETESIFMEPIHLSSAIAAKQIINEELKPPGVRADAECPGMLESAEQLLVEDLYNRVREKMDDTSLYNTPCVLDLQRALVQDRQEAPWNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGVYTGPEFYTGLEIQYLGVEVDDFPEVDISQHFRKASEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVRKKRAIYPNEGFLKQLRELNEKLMEEREEDYGREGGSAEAEEGEGTGSMLGARVHALTVEEEDDSASHLSGSSLGKATQASKPLTLIDEEEEEKLYEQWKKGQGLLSDKVPQDGGGWRSASSGQGGEELEDEDVERIIQEWQSRNERYQAEGYRRWGREEEKEEESDAGSSVGRRRRTLSESSAWESVSSHDIWVLKQQLELNRPDHGRRRRADSMSSESTWDAWNERLLEIEKEASRRYHAKSKREEAADRSSEAGSRVREDDEDSVGSEASSFYNFCSRNKDKLTALERWKIKRIQFGFHKKDLGAGDSSGEPGAEEAVGEKNPSDVSLTAYQAWKLKHQKKVGSENKEEVVELSKGEDSALAKKRQRRLELLERSRQTLEESQSMASWEADSSTASGSIPLSAFWSADPSVSADGDTTSVLSTQSHRSHLSQAASNIAGCSTSNPTTPLPNLPVGPGDTISIASIQNWIANVVSETLAQKQNEMLLLSRSPSVASMKAVPAASCLGDDQVSMLSGHSSSSLGGCLLPQSQARPSSDMQSVLSCNTTLSSPAESCRSKVRGTSKPIFSLFADNVDLKELGRKEKEMQMELREKMSEYKMEKLASDNKRSSLFKKKKVKEDEDDGVGDGDEDTDSAIGSFRYSSRSNSQKPETDTCSSLAVCDHYASGSRVGKEMDSSINKWLSGLRTEEKPPFQSDWSGSSRGKYTRSSLLRETESKSSSYKFSKSQSEEQDTSSYHEANGNSVRSTSRFSSSSTREGREMHKFSRSTYNETSSSREESPEPYFFRRTPESSEREESPEPQRPNWARSRDWEDVEESSKSDFSEFGAKRKFTQSFMRSEEEGEKERTENREEGRFASGRRSQYRRSTDREEEEEMDDEAIIAAWRRRQEETRTKLQKRRED", "length": 1158 }, "evidence": [ { "id": "A0A5K1V146", "url": "https://omabrowser.org/oma/group/A0A5K1V146/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V146", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of MAPK cascade", "id": "GO:0043409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043409", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V146", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein tyrosine/serine/threonine phosphatase activity", "id": "GO:0008138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008138", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V146", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146" } ], "pmid": "" }, { "name": "MAP kinase phosphatase activity", "id": "GO:0033549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033549", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V146", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1V146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 201, "end_pos": 260, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5K1V146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V146" }, { "id": "PS50054", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50054" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 280, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 198, "end_pos": 200 }, { "start_pos": 580, "end_pos": 582 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1V523-1", "uniprot_ac": "A0A5K1V523", "uniprot_id": "A0A5K1V523_PIG", "mass": { "chemical_mass": 162491.0, "monoisotopic_mass": 162491.0 }, "refseq": {}, "gene_names": [ { "name": "RAD54L2", "type": "recommended", "evidence": [ { "id": "A0A5K1V523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ] } ], "protein_names": [ { "name": "Helicase ARIP4", "type": "recommended", "evidence": [ { "id": "A0A5K1V523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523/entry#names_and_taxonomy" } ] }, { "name": "Androgen receptor-interacting protein 4", "type": "synonym", "evidence": [ { "id": "A0A5K1V523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523/entry#names_and_taxonomy" } ] }, { "name": "RAD54-like protein 2", "type": "synonym", "evidence": [ { "id": "A0A5K1V523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RAD54L2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523", "locus": { "chromosome": "13", "start_pos": 33885832, "end_pos": 33820071, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011425", "url": "https://www.ensembl.org/id/ENSSSCG00000011425" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011425", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011425", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18069", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18069", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45797", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45797", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45797:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45797:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1V523-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTEDFWEHVELEDAEEEEEEEEEVAVEEHGRDDEEDLLDDPSLEDMCGTECAQLGEDGQRPPRCTSTTSSQSEPSEQLRRHQGKSLASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEFLPEEIVLRASDGPQLPPRVLTQEVICLDSSSGSEDEKSSRDEVIELSSGEEDTLHIVDSSESVSEEDEEEEKGGTHVNDVLNQRDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPAPEALPADNKPEEIQPRFFKVHILNDEHKTMAARAKVMADWVSEGGVLLMGYEMYRLLTLKKSFTTSRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESLANEQDLDVEELGSAGTSARCPSQGTKSKGEDSTLASAVGEATNTKFLQGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCLPGAEGQGVQKWVRNVSYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCHIYRLVADFTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHFVEKEPAPQASLNIKGIKEPVLQLACLKYPHLITKEPFEHESLLLNRKDHKLTKAEKKAAKKSYEEDKRTSVPYTRPSYAQYYPASDQSLTSIPAFSQRNWQPTLKSDEKPVASVRPVQSTPIPMMPRHVPLGGSVSAASSTNPAMNFPINYLQRAGVLVQKVVTTTDIVIPGLNSSTDVQARINAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKAPEDGRMAASGSQGPSLESTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESRQSSPSSNATLPGPPAQLVDSSTVPGTALGTEPRHGGHCLNSSLLGTGQPCGDRHPVLDLRGHKRKLATPPAAQESTRRRSRKGHLPAPVQPYEHGYPVSGGFAMPPVSLNHNLTPPFTSQAGENTLFMGTTPSYYQLSNLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLNPSVPGILPSYSLPFSQPLLSEPRMFAPFPSPVLSSNLSRGMSVYPGYMSPHAGYPAGGLLRSQVPPFDSHEVAEVGFSSNEDEDKDDDVIEVTGK", "length": 1461, "header": "tr|A0A5K1V523-1|A0A5K1V523_PIG Isoform 1 of Helicase ARIP4 OS=Sus scrofa OX=9823 GN=RAD54L2 PE=3 SV=2 CANONICAL=A0A5K1V523-1" }, "isoforms": [ { "isoform_ac": "A0A5K1V523-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523/entry#A0A5K1V523-1", "sequence": { "sequence": "MSTEDFWEHVELEDAEEEEEEEEEVAVEEHGRDDEEDLLDDPSLEDMCGTECAQLGEDGQRPPRCTSTTSSQSEPSEQLRRHQGKSLASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEFLPEEIVLRASDGPQLPPRVLTQEVICLDSSSGSEDEKSSRDEVIELSSGEEDTLHIVDSSESVSEEDEEEEKGGTHVNDVLNQRDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPAPEALPADNKPEEIQPRFFKVHILNDEHKTMAARAKVMADWVSEGGVLLMGYEMYRLLTLKKSFTTSRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESLANEQDLDVEELGSAGTSARCPSQGTKSKGEDSTLASAVGEATNTKFLQGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCLPGAEGQGVQKWVRNVSYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCHIYRLVADFTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHFVEKEPAPQASLNIKGIKEPVLQLACLKYPHLITKEPFEHESLLLNRKDHKLTKAEKKAAKKSYEEDKRTSVPYTRPSYAQYYPASDQSLTSIPAFSQRNWQPTLKSDEKPVASVRPVQSTPIPMMPRHVPLGGSVSAASSTNPAMNFPINYLQRAGVLVQKVVTTTDIVIPGLNSSTDVQARINAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKAPEDGRMAASGSQGPSLESTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESRQSSPSSNATLPGPPAQLVDSSTVPGTALGTEPRHGGHCLNSSLLGTGQPCGDRHPVLDLRGHKRKLATPPAAQESTRRRSRKGHLPAPVQPYEHGYPVSGGFAMPPVSLNHNLTPPFTSQAGENTLFMGTTPSYYQLSNLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLNPSVPGILPSYSLPFSQPLLSEPRMFAPFPSPVLSSNLSRGMSVYPGYMSPHAGYPAGGLLRSQVPPFDSHEVAEVGFSSNEDEDKDDDVIEVTGK", "length": 1461, "header": "tr|A0A5K1V523-1|A0A5K1V523_PIG Isoform 1 of Helicase ARIP4 OS=Sus scrofa OX=9823 GN=RAD54L2 PE=3 SV=2 CANONICAL=A0A5K1V523-1" }, "locus": { "chromosome": "13", "start_pos": 33885658, "end_pos": 33820099, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012505.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012505.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012177.4", "url": "https://www.ensembl.org/id/ENSSSCP00000012177.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "DNA/RNA helicase activity", "id": "GO:0033677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033677", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" }, { "name": "R-loop processing", "id": "GO:0062176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062176", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V523", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1077, "end_pos": 1079, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1193, "end_pos": 1195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1226, "end_pos": 1228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1298, "end_pos": 1300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1402, "end_pos": 1404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 800, "end_pos": 802, "annotation": "n_glycosylation_sequon" }, { "start_pos": 891, "end_pos": 893, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1V523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 286, "end_pos": 506, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A5K1V523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V523" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 722, "end_pos": 890, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1077, "end_pos": 1079 }, { "start_pos": 1193, "end_pos": 1195 }, { "start_pos": 1226, "end_pos": 1228 }, { "start_pos": 1298, "end_pos": 1300 }, { "start_pos": 1402, "end_pos": 1404 }, { "start_pos": 773, "end_pos": 775 }, { "start_pos": 800, "end_pos": 802 }, { "start_pos": 891, "end_pos": 893 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1V9E1-1", "uniprot_ac": "A0A5K1V9E1", "uniprot_id": "A0A5K1V9E1_PIG", "mass": { "chemical_mass": 58540.0, "monoisotopic_mass": 58540.0 }, "refseq": {}, "gene_names": [ { "name": "FANCE", "type": "recommended", "evidence": [ { "id": "A0A5K1V9E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1" } ] } ], "protein_names": [ { "name": "FA complementation group E", "type": "synonym", "evidence": [ { "id": "A0A5K1V9E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V9E1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FANCE", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1", "locus": { "chromosome": "7", "start_pos": 31327142, "end_pos": 31313388, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001546", "url": "https://www.ensembl.org/id/ENSSSCG00000001546" } ] } } ], "crossref": [ { "id": "A0A5K1V9E1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1V9E1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001546", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001546", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07439", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07439", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR021025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039685", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039685", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR32094", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32094", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32094:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32094:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11510", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11510", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5K1V9E1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1V9E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPEAAPAQAEGAEPAPWAQLEAPSRLLLQALQAGPDGARRGLGVLRLGGRGRDPFCWGGVLEALCREEPVVEGPDCRLELKPLLLRLPPLCRRNLMSLLMAVWPSLPKHSLLSVLQTAGQDPSPDPDPWLQVLGEFLRRDLGVGASLEGASPLSKRCQKQLRGLCRQLGQGGRKVKLLRASDPKEEEKEEAKDSQRPGKRRKEPEEEPAHPEGERAPKRFRCSEEEEGHEEKRPEQGSLDSLADGGGALPMKHQPVVGAEPPEAAQSPEGAEGLPGSLELPRAVQDQVPRLQQLLKTLGKGLEGLEGVPPVELQLLHECSPGQVDLLCARLQLPQLSDTGLLQLCTWLLALSPDLSLGSATVLTRSLFLGRILSLTSSASRLLITALTSFCAKYSYAVCTALLGPVLQAPKTGPAQRELLCCLMKDKALEPDMQVLMLGRLLELPWKEETFLVLQSLLERQVEIPSEKFRVLMEKLCKEGPAATTSIAYAKLTLTVLTKYQAHITEPQRLGLATALELNTTFLRKSLLAALRHLAP", "length": 538, "header": "tr|A0A5K1V9E1-1|A0A5K1V9E1_PIG Isoform 1 of FA complementation group E OS=Sus scrofa OX=9823 GN=FANCE PE=4 SV=1 CANONICAL=A0A5K1V9E1-1" }, "isoforms": [ { "isoform_ac": "A0A5K1V9E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1/entry#A0A5K1V9E1-1", "sequence": { "sequence": "MAAPEAAPAQAEGAEPAPWAQLEAPSRLLLQALQAGPDGARRGLGVLRLGGRGRDPFCWGGVLEALCREEPVVEGPDCRLELKPLLLRLPPLCRRNLMSLLMAVWPSLPKHSLLSVLQTAGQDPSPDPDPWLQVLGEFLRRDLGVGASLEGASPLSKRCQKQLRGLCRQLGQGGRKVKLLRASDPKEEEKEEAKDSQRPGKRRKEPEEEPAHPEGERAPKRFRCSEEEEGHEEKRPEQGSLDSLADGGGALPMKHQPVVGAEPPEAAQSPEGAEGLPGSLELPRAVQDQVPRLQQLLKTLGKGLEGLEGVPPVELQLLHECSPGQVDLLCARLQLPQLSDTGLLQLCTWLLALSPDLSLGSATVLTRSLFLGRILSLTSSASRLLITALTSFCAKYSYAVCTALLGPVLQAPKTGPAQRELLCCLMKDKALEPDMQVLMLGRLLELPWKEETFLVLQSLLERQVEIPSEKFRVLMEKLCKEGPAATTSIAYAKLTLTVLTKYQAHITEPQRLGLATALELNTTFLRKSLLAALRHLAP", "length": 538, "header": "tr|A0A5K1V9E1-1|A0A5K1V9E1_PIG Isoform 1 of FA complementation group E OS=Sus scrofa OX=9823 GN=FANCE PE=4 SV=1 CANONICAL=A0A5K1V9E1-1" }, "locus": { "chromosome": "7", "start_pos": 31326138, "end_pos": 31313388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026873.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026873.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020351.3", "url": "https://www.ensembl.org/id/ENSSSCP00000020351.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V9E1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" }, { "id": "R-SSC-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Fanconi anaemia nuclear complex", "id": "GO:0043240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043240", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V9E1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V9E1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V9E1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1V9E1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1V9E1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 538, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1V9E1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1V9E1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1V9E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1V9E1" }, { "id": "PF11510", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11510" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fanconi Anaemia group E protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 278, "end_pos": 536, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 521, "end_pos": 523 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1VDW0-1", "uniprot_ac": "A0A5K1VDW0", "uniprot_id": "A0A5K1VDW0_PIG", "mass": { "chemical_mass": 33014.0, "monoisotopic_mass": 33014.0 }, "refseq": {}, "gene_names": [ { "name": "ARPC5L", "type": "recommended", "evidence": [ { "id": "A0A5K1VDW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0" } ] } ], "protein_names": [ { "name": "Actin-related protein 2/3 complex subunit 5", "type": "recommended", "evidence": [ { "id": "A0A5K1VDW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VDW0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0#function" }, { "database": "UniProtKB", "id": "RU004301", "url": "https://www.uniprot.org/uniprotkb/RU004301#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VDW0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARPC5L", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0", "locus": { "chromosome": "1", "start_pos": 265654018, "end_pos": 265642260, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005596", "url": "https://www.ensembl.org/id/ENSSSCG00000005596" } ] } } ], "crossref": [ { "id": "A0A5K1VDW0", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1VDW0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005596", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005596", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12644", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12644", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5K1VDW0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VDW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQDFQEVEGTREERAEDSAEPGAPPVQERSRRRVQLWRRPGAEPSRDWAPVSQSGRLRLHEDRSPGESHKAVFQNSFSALPATPRPSLLPALPVPAWPGSGRAAAAARGGGGGGAGSPLPAPEPEPVPSGVEWRSAPERSWLSGRRAPAMARNTLSSRFRRVDIDEFDENKFVDEQEEAAAAAAEPGPDPSEVDGLLRQGDMLRAFHAALRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV", "length": 303, "header": "tr|A0A5K1VDW0-1|A0A5K1VDW0_PIG Isoform 1 of Actin-related protein 2/3 complex subunit 5 OS=Sus scrofa OX=9823 GN=ARPC5L PE=1 SV=1 CANONICAL=A0A5K1VDW0-1" }, "isoforms": [ { "isoform_ac": "A0A5K1VDW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0/entry#A0A5K1VDW0-1", "sequence": { "sequence": "MRQDFQEVEGTREERAEDSAEPGAPPVQERSRRRVQLWRRPGAEPSRDWAPVSQSGRLRLHEDRSPGESHKAVFQNSFSALPATPRPSLLPALPVPAWPGSGRAAAAARGGGGGGAGSPLPAPEPEPVPSGVEWRSAPERSWLSGRRAPAMARNTLSSRFRRVDIDEFDENKFVDEQEEAAAAAAEPGPDPSEVDGLLRQGDMLRAFHAALRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV", "length": 303, "header": "tr|A0A5K1VDW0-1|A0A5K1VDW0_PIG Isoform 1 of Actin-related protein 2/3 complex subunit 5 OS=Sus scrofa OX=9823 GN=ARPC5L PE=1 SV=1 CANONICAL=A0A5K1VDW0-1" }, "locus": { "chromosome": "1", "start_pos": 265653510, "end_pos": 265643490, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006154.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006154.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005995.4", "url": "https://www.ensembl.org/id/ENSSSCP00000005995.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VDW0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VDW0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VDW0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VDW0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0" } ], "pmid": "" }, { "name": "Arp2/3 complex-mediated actin nucleation", "id": "GO:0034314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034314", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VDW0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VDW0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cortical cytoskeleton", "id": "GO:0030863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030863", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VDW0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0" } ], "pmid": "" }, { "name": "Arp2/3 protein complex", "id": "GO:0005885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005885", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VDW0", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VDW0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1VDW0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 303, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1VDW0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1VDW0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 272, "end_pos": 274 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1VFF8-1", "uniprot_ac": "A0A5K1VFF8", "uniprot_id": "A0A5K1VFF8_PIG", "mass": { "chemical_mass": 32274.0, "monoisotopic_mass": 32274.0 }, "refseq": {}, "gene_names": [ { "name": "SGCD", "type": "recommended", "evidence": [ { "id": "A0A5K1VFF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8" } ] } ], "protein_names": [ { "name": "Sarcoglycan delta", "type": "synonym", "evidence": [ { "id": "A0A5K1VFF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VFF8", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SGCD", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8", "locus": { "chromosome": "16", "start_pos": 66452178, "end_pos": 66887924, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000058577", "url": "https://www.ensembl.org/id/ENSSSCG00000058577" } ] } } ], "crossref": [ { "id": "A0A5K1VFF8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1VFF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017063", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017063", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12939:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12939:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9913351", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9913351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5K1VFF8", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VFF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RMPQEQYTHHRSTMPSSEGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLYAKEIQSRPGNALYFKSARNVTVNILNEQTKVLTQLITGPNAIEAYGKKFEVKTVSGKLLFSADNNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRSLVMEAPKGVEINAEAGNMEATCRTELRLESKDGEIKLDAAKIKLPRLPHGSYTPAGTRQKVFEICVCANGRLFLSQAGTGSTCQINTSVCL", "length": 290, "header": "tr|A0A5K1VFF8-1|A0A5K1VFF8_PIG Isoform 1 of Sarcoglycan delta OS=Sus scrofa OX=9823 GN=SGCD PE=1 SV=1 CANONICAL=A0A5K1VFF8-1" }, "isoforms": [ { "isoform_ac": "A0A5K1VFF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8/entry#A0A5K1VFF8-1", "sequence": { "sequence": "RMPQEQYTHHRSTMPSSEGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLYAKEIQSRPGNALYFKSARNVTVNILNEQTKVLTQLITGPNAIEAYGKKFEVKTVSGKLLFSADNNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRSLVMEAPKGVEINAEAGNMEATCRTELRLESKDGEIKLDAAKIKLPRLPHGSYTPAGTRQKVFEICVCANGRLFLSQAGTGSTCQINTSVCL", "length": 290, "header": "tr|A0A5K1VFF8-1|A0A5K1VFF8_PIG Isoform 1 of Sarcoglycan delta OS=Sus scrofa OX=9823 GN=SGCD PE=1 SV=1 CANONICAL=A0A5K1VFF8-1" }, "locus": { "chromosome": "16", "start_pos": 66887924, "end_pos": 66454627, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104273.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104273.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079691.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079691.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VFF8", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9913351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9913351", "resource": "Reactome", "description": "Formation of the dystrophin-glycoprotein complex (DGC)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VFF8", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VFF8", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8" } ], "pmid": "" }, { "name": "sarcoglycan complex", "id": "GO:0016012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016012", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VFF8", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VFF8", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8" } ], "pmid": "" }, { "name": "cardiac muscle tissue development", "id": "GO:0048738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048738", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VFF8", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VFF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1VFF8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 290, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1VFF8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1VFF8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1VGW2-1", "uniprot_ac": "A0A5K1VGW2", "uniprot_id": "A0A5K1VGW2_PIG", "mass": { "chemical_mass": 228525.0, "monoisotopic_mass": 228525.0 }, "refseq": {}, "gene_names": [ { "name": "GON4L", "type": "recommended", "evidence": [ { "id": "A0A5K1VGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2" } ] } ], "protein_names": [ { "name": "GON-4-like protein", "type": "recommended", "evidence": [ { "id": "A0A5K1VGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2/entry#names_and_taxonomy" } ] }, { "name": "GON-4 homolog", "type": "synonym", "evidence": [ { "id": "A0A5K1VGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a key transcription regulator of histones. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with GON4L and MIZF. Together with CRAMP1, binds to the promoters of H1 genes (H1-2, H1-3, H1-4, H1-5 and H1-10/H1x), driving their transcription. Also acts as a transcription corepressor, as part of a complex with YY1, SIN3A and HDAC1. Required for B-cell lymphopoiesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VGW2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2#function" }, { "database": "UniProtKB", "id": "ARBA00094466", "url": "https://www.uniprot.org/uniprotkb/ARBA00094466#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VGW2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GON4L", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000006510", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006510", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12202", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12202", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16088", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16088", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16088:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16088:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02671", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02671", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5K1VGW2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VGW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPCKKRRTTPTESPQHQGNQEEGDLDLESPVKPESDQVKDLGSVSLSWGPNHGRAAGLEVQSVHDAGNLLAMEDPSLSSRVLTQDANAPVLETLDVAISQGITLPSLEASQPLNIHICKGKLQASSSRRGKKITLRPGLVTQEDRGDHPIAKEPFLGEPSEEVKDEGEEQDSEENEKRRKKKKGTKRKRDGRGQEEGTLACDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEDDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSETMDDSLIAFRTRSKMPLKDVPLGQLEAELRAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEERVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELLEQLKMKKSSAKQQQEVERVKPQSEKVHQTLILDPAQRRRLQQQMQQHVQLLTQIHLLATSNPNLSSEASTTRIFLKELGTFAQSSIALHHQFNPKFQTLFQPCNLMGAMQLIEDFNTHVSVDWSPRKTVKKTAHEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIFFTKAEDFYKKTKQLPILMKCCEEIQPHQWKPPVEREEHRLPFWLKASLPSIQEELQHIADGAREVGHVTGSAEISSEPGLGKGSSELGSETRYPLLLPKGVVLKLKPVANYFSRKAWRQKRSSVLKPLIRPSPSLQPSSSSGKTPVRSAQAEAPPSKVMVRIPHMIQPATVLQPVPGGPPQGVAAGERFESPAALPTTPAEARTSFPLPEPQTLLSSAPVPKVMLPSLGPSRFRKPCVKRRASRRKGAKASLCLKPAPLIHPAPIIFTVPAATVKVVSLGSGCNMLQPVSATVAQSPQTIPITTLLVNPTSFPCPLNQPLVASSIPPLIVSGNSVNLPVPSAPEDKAQVSVDIGCPLAEGKNAFQVLEPKLEPQEPSPLCAAVFPKEEHSPGPLPPDRVCQEQLSESSAYGWTIVKTEEGRQALEPLPQAFQESLTSSPEALEEIVKMEPKDPGEELSAECAEQDTHEDIKEEHSVELNTGFPSEEASGTREVKKQMVLQQEEERRQPAQTSSASQEPPDERNSGDVGKGSPRNASSATDPEMVLSSPPGKPEDLSSADGQSVGTPAGPETGGEKDVPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAIGDPAEKPPTTFASPKTAPEVETSRTPPGESIKAAGKGRSNHRARSKRGSRARASKDTSKLLLLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRQTAVDLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQSCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTASKNKRRKEIGVQNHDKEAEWPDGAKDCACSCHDGGPDSKLKKSKRRSCSHCNSKVCDSKSYKSKEPHESVGSSPHREASPMPGAKEAGQGKDAMEEEAPEERESIEASQSRTGRSTRRGEMPVPAGLAVGSALLSPQEVTFTDQLLLDGPPPCSPETPQLPSTTETVLYAAGSDQAGPEALSCPKAASRPQIEEEGPAAGGESEAPLLVWDASETEKLPGTVEPPASFPSPDSSRTGDLGRRQVSGKPDTPESWLPSSRAGTTTTADRVSPVHESSSSGIDTSDTSPKAPRGGLAKDSGVQGKGPAGEPQPKATEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPQTFSIISQQLGNKTPSEVSHRFRELMQLFHTACEASSEDEDDATSTSNTDQLSDHGDLLSEEELDE", "length": 2070, "header": "tr|A0A5K1VGW2-1|A0A5K1VGW2_PIG Isoform 1 of GON-4-like protein OS=Sus scrofa OX=9823 GN=GON4L PE=4 SV=2 CANONICAL=A0A5K1VGW2-1" }, "isoforms": [ { "isoform_ac": "A0A5K1VGW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2/entry#A0A5K1VGW2-1", "sequence": { "sequence": "MLPCKKRRTTPTESPQHQGNQEEGDLDLESPVKPESDQVKDLGSVSLSWGPNHGRAAGLEVQSVHDAGNLLAMEDPSLSSRVLTQDANAPVLETLDVAISQGITLPSLEASQPLNIHICKGKLQASSSRRGKKITLRPGLVTQEDRGDHPIAKEPFLGEPSEEVKDEGEEQDSEENEKRRKKKKGTKRKRDGRGQEEGTLACDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEDDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSETMDDSLIAFRTRSKMPLKDVPLGQLEAELRAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEERVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELLEQLKMKKSSAKQQQEVERVKPQSEKVHQTLILDPAQRRRLQQQMQQHVQLLTQIHLLATSNPNLSSEASTTRIFLKELGTFAQSSIALHHQFNPKFQTLFQPCNLMGAMQLIEDFNTHVSVDWSPRKTVKKTAHEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIFFTKAEDFYKKTKQLPILMKCCEEIQPHQWKPPVEREEHRLPFWLKASLPSIQEELQHIADGAREVGHVTGSAEISSEPGLGKGSSELGSETRYPLLLPKGVVLKLKPVANYFSRKAWRQKRSSVLKPLIRPSPSLQPSSSSGKTPVRSAQAEAPPSKVMVRIPHMIQPATVLQPVPGGPPQGVAAGERFESPAALPTTPAEARTSFPLPEPQTLLSSAPVPKVMLPSLGPSRFRKPCVKRRASRRKGAKASLCLKPAPLIHPAPIIFTVPAATVKVVSLGSGCNMLQPVSATVAQSPQTIPITTLLVNPTSFPCPLNQPLVASSIPPLIVSGNSVNLPVPSAPEDKAQVSVDIGCPLAEGKNAFQVLEPKLEPQEPSPLCAAVFPKEEHSPGPLPPDRVCQEQLSESSAYGWTIVKTEEGRQALEPLPQAFQESLTSSPEALEEIVKMEPKDPGEELSAECAEQDTHEDIKEEHSVELNTGFPSEEASGTREVKKQMVLQQEEERRQPAQTSSASQEPPDERNSGDVGKGSPRNASSATDPEMVLSSPPGKPEDLSSADGQSVGTPAGPETGGEKDVPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAIGDPAEKPPTTFASPKTAPEVETSRTPPGESIKAAGKGRSNHRARSKRGSRARASKDTSKLLLLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRQTAVDLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQSCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTASKNKRRKEIGVQNHDKEAEWPDGAKDCACSCHDGGPDSKLKKSKRRSCSHCNSKVCDSKSYKSKEPHESVGSSPHREASPMPGAKEAGQGKDAMEEEAPEERESIEASQSRTGRSTRRGEMPVPAGLAVGSALLSPQEVTFTDQLLLDGPPPCSPETPQLPSTTETVLYAAGSDQAGPEALSCPKAASRPQIEEEGPAAGGESEAPLLVWDASETEKLPGTVEPPASFPSPDSSRTGDLGRRQVSGKPDTPESWLPSSRAGTTTTADRVSPVHESSSSGIDTSDTSPKAPRGGLAKDSGVQGKGPAGEPQPKATEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPQTFSIISQQLGNKTPSEVSHRFRELMQLFHTACEASSEDEDDATSTSNTDQLSDHGDLLSEEELDE", "length": 2070, "header": "tr|A0A5K1VGW2-1|A0A5K1VGW2_PIG Isoform 1 of GON-4-like protein OS=Sus scrofa OX=9823 GN=GON4L PE=4 SV=2 CANONICAL=A0A5K1VGW2-1" }, "locus": { "chromosome": "4", "start_pos": 94247951, "end_pos": 94167086, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028079.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028079.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024329.4", "url": "https://www.ensembl.org/id/ENSSSCP00000024329.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VGW2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VGW2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VGW2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VGW2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VGW2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VGW2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1239, "end_pos": 1241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1618, "end_pos": 1620, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1971, "end_pos": 1973, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2016, "end_pos": 2018, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1VGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGW2" }, { "id": "PS50090", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50090" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb-like", "eco_id": "ECO_0000259", "start_pos": 1985, "end_pos": 2030, "start_aa": "Trp", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1239, "end_pos": 1241 }, { "start_pos": 1618, "end_pos": 1620 }, { "start_pos": 1971, "end_pos": 1973 }, { "start_pos": 2016, "end_pos": 2018 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 281, "end_pos": 283 }, { "start_pos": 594, "end_pos": 596 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1VH81-1", "uniprot_ac": "A0A5K1VH81", "uniprot_id": "A0A5K1VH81_PIG", "mass": { "chemical_mass": 28712.0, "monoisotopic_mass": 28712.0 }, "refseq": {}, "gene_names": [ { "name": "MAPK4", "type": "recommended", "evidence": [ { "id": "A0A5K1VH81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81" } ] } ], "protein_names": [ { "name": "mitogen-activated protein kinase", "type": "recommended", "evidence": [ { "id": "A0A5K1VH81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.24", "type": "synonym", "evidence": [ { "id": "A0A5K1VH81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VH81", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MAPK4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81", "locus": {} } ], "crossref": [ { "id": "A0A5K1VH81", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1VH81", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004520", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004520", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5K1VH81", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VH81-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VH83", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VH83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEKGDCIASVYGYDLGGRFIDLQPLGFGVNGLVLSAVDSRARRKVAVKKITLSDTRSMKHALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTLTEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKVRLAGLLMQVVNGILKNVQGIPNSSGTGGPGYVLGEAGGPKKDHWPEKLLGEKGVLVLSLASAMAVTNNSRLYKRGVD", "length": 260, "header": "tr|A0A5K1VH81-1|A0A5K1VH81_PIG Isoform 1 of mitogen-activated protein kinase OS=Sus scrofa OX=9823 GN=MAPK4 PE=3 SV=1 CANONICAL=A0A5K1VH81-1" }, "isoforms": [ { "isoform_ac": "A0A5K1VH81-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81/entry#A0A5K1VH81-1", "sequence": { "sequence": "MAEKGDCIASVYGYDLGGRFIDLQPLGFGVNGLVLSAVDSRARRKVAVKKITLSDTRSMKHALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTLTEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKVRLAGLLMQVVNGILKNVQGIPNSSGTGGPGYVLGEAGGPKKDHWPEKLLGEKGVLVLSLASAMAVTNNSRLYKRGVD", "length": 260, "header": "tr|A0A5K1VH81-1|A0A5K1VH81_PIG Isoform 1 of mitogen-activated protein kinase OS=Sus scrofa OX=9823 GN=MAPK4 PE=3 SV=1 CANONICAL=A0A5K1VH81-1" }, "locus": { "chromosome": "1", "start_pos": 100220685, "end_pos": 100219906, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033301.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033301.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030164.3", "url": "https://www.ensembl.org/id/ENSSSCP00000030164.3" } ] } }, { "isoform_ac": "A0A5K1VH83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81/entry#A0A5K1VH83-1", "sequence": { "sequence": "MAEKGDCIASVYGYDLGGRFIDLQPLGFGVNGLVLSAVDSRARRKVAVKKITLSDTRSMKHALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTLTEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGTP", "length": 233, "header": "tr|A0A5K1VH83-1|A0A5K1VH83_PIG Computationally mapped isoform of mitogen-activated protein kinase OS=Sus scrofa OX=9823 GN=MAPK4 PE=3 SV=1 CANONICAL=A0A5K1VH81-1" }, "locus": { "chromosome": "1", "start_pos": 100288933, "end_pos": 100219906, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032864.4", "url": "https://www.ensembl.org/id/ENSSSCT00000032864.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030322.3", "url": "https://www.ensembl.org/id/ENSSSCP00000030322.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VH81", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VH81", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81" } ], "pmid": "" }, { "name": "MAP kinase activity", "id": "GO:0004707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004707", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VH81", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VH81", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1VH81-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 260, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1VH81-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1VH81" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1VH81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VH81" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 260, "start_aa": "Phe", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 250, "end_pos": 252 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1VKG5-1", "uniprot_ac": "A0A5K1VKG5", "uniprot_id": "A0A5K1VKG5_PIG", "mass": { "chemical_mass": 28360.0, "monoisotopic_mass": 28360.0 }, "refseq": { "ac": "XP_005665023", "name": "tumor necrosis factor receptor superfamily member 9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665023" }, "gene_names": [ { "name": "TNFRSF9", "type": "recommended", "evidence": [ { "id": "A0A5K1VKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5" } ] }, { "name": "TNFRSF9", "type": "synonym", "evidence": [ { "id": "XP_005665023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665023" } ] } ], "protein_names": [ { "name": "TNF receptor superfamily member 9", "type": "synonym", "evidence": [ { "id": "A0A5K1VKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5/entry#names_and_taxonomy" } ] }, { "name": "tumor necrosis factor receptor superfamily member 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005665023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665023" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VKG5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TNFRSF9", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5", "locus": { "chromosome": "6", "start_pos": 68590360, "end_pos": 68609695, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003386", "url": "https://www.ensembl.org/id/ENSSSCG00000003386" } ] } } ], "crossref": [ { "id": "A0A5K1VKG5", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1VKG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003386", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003386", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13410", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13410", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519368", "url": "https://www.ncbi.nlm.nih.gov/gene/100519368", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001368", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001368", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A5K1VKG5", "url": "https://www.orthodb.org/?gene=A0A5K1VKG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1RII3", "url": "https://www.orthodb.org/?gene=F1RII3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47139", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47139", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47139:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47139:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5669034", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5669034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005665023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665023", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5K1VKG5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VKG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RII3", "url": "https://www.uniprot.org/uniprotkb/F1RII3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RII3-1", "url": "https://www.uniprot.org/uniprotkb/F1RII3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQDFIMGNGYYNIVATVLLVMNFERTRSVPDPCSNCSAGTFCGKNIQELCMPCPSNSFSSTSGQKACNVCRKCEGVFRTKKECSSTSNAVCECVPGFRCLGAGCAMCEEYCQQGQELTQEGCKDCSFGTFNDEEHGVCRPWTDCSLAGKPVLMNGTKARDVVCGPRPTDFSPGTPSTTMPVPGGEPGHTSHVIIFFLALMSTAVFVLVSYLALRFSVVQQGRKKLLYIVKQPFLKPAQTVQEEDACSCRFPEEEEGECEL", "length": 260, "header": "tr|A0A5K1VKG5-1|A0A5K1VKG5_PIG Isoform 1 of TNF receptor superfamily member 9 OS=Sus scrofa OX=9823 GN=TNFRSF9 PE=4 SV=1 CANONICAL=A0A5K1VKG5-1" }, "isoforms": [ { "isoform_ac": "A0A5K1VKG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5/entry#A0A5K1VKG5-1", "sequence": { "sequence": "MQDFIMGNGYYNIVATVLLVMNFERTRSVPDPCSNCSAGTFCGKNIQELCMPCPSNSFSSTSGQKACNVCRKCEGVFRTKKECSSTSNAVCECVPGFRCLGAGCAMCEEYCQQGQELTQEGCKDCSFGTFNDEEHGVCRPWTDCSLAGKPVLMNGTKARDVVCGPRPTDFSPGTPSTTMPVPGGEPGHTSHVIIFFLALMSTAVFVLVSYLALRFSVVQQGRKKLLYIVKQPFLKPAQTVQEEDACSCRFPEEEEGECEL", "length": 260, "header": "tr|A0A5K1VKG5-1|A0A5K1VKG5_PIG Isoform 1 of TNF receptor superfamily member 9 OS=Sus scrofa OX=9823 GN=TNFRSF9 PE=4 SV=1 CANONICAL=A0A5K1VKG5-1" }, "locus": { "chromosome": "6", "start_pos": 68608759, "end_pos": 68592207, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035166.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035166.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030379.3", "url": "https://www.ensembl.org/id/ENSSSCP00000030379.3" } ] } }, { "isoform_ac": "F1RII3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5/entry#F1RII3-1", "sequence": { "sequence": "MQDFIMGNGYYNIVATVLLVMNFERTRSVPDPCSNCSAGTFCGKNIQELCMPCPSNSFSSTSGQKACNVCRKCEGVFRTKKECSSTSNAVCECVPGFRCLGAGCAMCEEYCQQGQELTQEGCKDCSFGTFNDEEHGVCRPWTDCSLAGKPVLMNGTKARDVVCGPRPTDFSPGHTSHVIIFFLALMSTAVFVLVSYLALRFSVVQQGRKKLLYIVKQPFLKPAQTVQEEDACSCRFPEEEEGECEL", "length": 246, "header": "tr|F1RII3-1|A0A5K1VKG5_PIG Computationally mapped isoform of TNF receptor superfamily member 9 OS=Sus scrofa OX=9823 GN=TNFRSF9 PE=4 SV=3 CANONICAL=A0A5K1VKG5-1" }, "locus": { "chromosome": "6", "start_pos": 68608759, "end_pos": 68592207, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003757.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003757.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003671.3", "url": "https://www.ensembl.org/id/ENSSSCP00000003671.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RII3", "url": "https://www.uniprot.org/uniprotkb/F1RII3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5669034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5669034", "resource": "Reactome", "description": "TNFs bind their physiological receptors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VKG5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VKG5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VKG5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VKG5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VKG5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VKG5", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1VKG5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 260, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1VKG5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1VKG5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1VKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VKG5" }, { "id": "PS50050", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50050" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TNFR-Cys", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 91, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 35, "end_pos": 37 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1VN55-1", "uniprot_ac": "A0A5K1VN55", "uniprot_id": "A0A5K1VN55_PIG", "mass": { "chemical_mass": 46931.0, "monoisotopic_mass": 46931.0 }, "refseq": { "ac": "XP_013854581", "name": "S100P-binding protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013854581" }, "gene_names": [ { "name": "S100PBP", "type": "recommended", "evidence": [ { "id": "A0A5K1VN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VN55" } ] }, { "name": "S100PBP", "type": "synonym", "evidence": [ { "id": "XP_013854581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013854581" } ] } ], "protein_names": [ { "name": "S100P-binding protein", "type": "recommended", "evidence": [ { "id": "A0A5K1VN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VN55/entry#names_and_taxonomy" } ] }, { "name": "S100P-binding protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013854581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013854581" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VN55", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VN55" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "S100PBP", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VN55", "locus": { "chromosome": "6", "start_pos": 89160045, "end_pos": 89122469, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000022801", "url": "https://www.ensembl.org/id/ENSSSCG00000022801" } ] } } ], "crossref": [ { "id": "A0A5K1VN55", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1VN55", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000022801", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022801", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100621255", "url": "https://www.ncbi.nlm.nih.gov/gene/100621255", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621255", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621255", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HHMQNSK", "url": "https://omabrowser.org/oma/group/HHMQNSK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5K1VN55", "url": "https://www.orthodb.org/?gene=A0A5K1VN55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14455", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14455", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14455:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14455:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15427", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15427", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013854581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013854581", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5K1VN55", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VN55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VN55-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VN55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTCSLVPSEQSSGASLLPKDSAPFSWGSLDEDGLDDSLLELSEGEDDGHFSFTEEEIQELLKDDDLSNEHLSKERGLLNGDNRNVEKGGKGSQILLDTPHEKNSLYNLGPVTETPGLFKLPQLSTSVGHGPTPKPLNRRFALEKNLIKVTVAPFDPRVCDVVLDKDKTDTSKDIEKPSSLGEEMREDGLSPKENTLCTESEGISPSNSAYNGPPFPSSNNNFQQTVSDKNIPDNKKPTPASSQILDHSETPNLGSSWRNRSHKPNLEVKFPVVSSSSNKKDVLDKDSGKLKVHEKRLGKVIPVLQAKTRTNVPTSSPSDLEKQKQSYLRNVIAHIEDPVDSNQGALGELCTLMDQVHHMQNQKWQHPSDLTRRNYARFRQKSLQRYSLTQWVDRNMRSHHRFQRLPDFQYSSFVSSHQQ", "length": 419, "header": "tr|A0A5K1VN55-1|A0A5K1VN55_PIG Isoform 1 of S100P-binding protein OS=Sus scrofa OX=9823 GN=S100PBP PE=4 SV=1 CANONICAL=A0A5K1VN55-1" }, "isoforms": [ { "isoform_ac": "A0A5K1VN55-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VN55/entry#A0A5K1VN55-1", "sequence": { "sequence": "MTCSLVPSEQSSGASLLPKDSAPFSWGSLDEDGLDDSLLELSEGEDDGHFSFTEEEIQELLKDDDLSNEHLSKERGLLNGDNRNVEKGGKGSQILLDTPHEKNSLYNLGPVTETPGLFKLPQLSTSVGHGPTPKPLNRRFALEKNLIKVTVAPFDPRVCDVVLDKDKTDTSKDIEKPSSLGEEMREDGLSPKENTLCTESEGISPSNSAYNGPPFPSSNNNFQQTVSDKNIPDNKKPTPASSQILDHSETPNLGSSWRNRSHKPNLEVKFPVVSSSSNKKDVLDKDSGKLKVHEKRLGKVIPVLQAKTRTNVPTSSPSDLEKQKQSYLRNVIAHIEDPVDSNQGALGELCTLMDQVHHMQNQKWQHPSDLTRRNYARFRQKSLQRYSLTQWVDRNMRSHHRFQRLPDFQYSSFVSSHQQ", "length": 419, "header": "tr|A0A5K1VN55-1|A0A5K1VN55_PIG Isoform 1 of S100P-binding protein OS=Sus scrofa OX=9823 GN=S100PBP PE=4 SV=1 CANONICAL=A0A5K1VN55-1" }, "locus": { "chromosome": "6", "start_pos": 89157563, "end_pos": 89128264, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029571.4", "url": "https://www.ensembl.org/id/ENSSSCT00000029571.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024892.2", "url": "https://www.ensembl.org/id/ENSSSCP00000024892.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 132, "start_aa": "Thr", "end_pos": 132, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr132", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 238, "start_aa": "Thr", "end_pos": 238, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr238", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VN55", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VN55" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621255", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621255", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZSX9-1", "protein_name": "S100P-binding protein", "gene_name": "S100pbp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTCSLLPSEQSSGTSFLPKDNASFSWGSSDEDELDDSLLEFSDGEEDDGHFSFTEEEIEMLLKDDDGGHNEYRARKSQILPHTPQENSLYSLGPAAETPGFLKLPQLSPSVGHGPTPSKSLNRHFVLEKNLIKVTVVAPFNPTVCDPVLDKDKIDSSKETEKPASLQEQTREDDLHPNESKRCTEPEGVSPNNSAWDGPLLSSPSNNNIEQTASDKNIPESKKPTPVFSQISNHSEVPNRKNSGSHKSGCEVRIPVVSSSSNRHAFDKDSGEAKGERRLGKVIPVLQTRTRMFSQSDLEKQKDIYLSKVIAHIEDPGDSNQGALGELDALMDQVHMQNPDWQHPSDLTTRNYARFRQRPLQRYSLSQWVDRNKRSHHRFQRLPDFSYSPYVSPHPQ", "length": 396 }, "evidence": [ { "id": "A0A5K1VN55", "url": "https://omabrowser.org/oma/group/A0A5K1VN55/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H934-1", "protein_name": "S100P-binding protein", "gene_name": "S100pbp", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTCSLLPSEQSSGTSFLPKDNASFSWGSSDEDELDDSLLEFSDGEEDDGHFSFTEEEIEMLLKDDDGGHEYGERKCQILPGTRRENSLYSLGPAAETPGFFKLPQLSTSVGHGPTPSKSLNRHFVLEKNLIKVTVVAPFNPTVCDPVLAKDKVDSSKDTENPASLGERIGEDDLHPNESKHCTEPEGVSPDNSARDGPLLSSPSNNNIEQTASDKNVPESKKPTPVFSQISNHSEVPNRGSSWKNSGSHKSGCEVRIPVVSSSSNRHTFDKDSGEVKSERRLGKVIPVLQTRTRMFSQSDLEKQKDIYLSKVIAHIEDPGDSNQGTLGELDALMDQVHMQNPDWQHPSDLTTRNYARFRQKPLQRYSLSQWVDRNKRSHHRFQRLPDFSYSPYVSSHPQ", "length": 399 }, "evidence": [ { "id": "A0A5K1VN55", "url": "https://omabrowser.org/oma/group/A0A5K1VN55/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3MHH3-1", "protein_name": "S100P-binding protein", "gene_name": "S100PBP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMCSLVPSEQSSGTSLLPKDNAPFSWSSLDEDELDDSLLELSDGEDDGHFSFTEEQIQELLKDDDLSNEHFPWGGGLPSDDSRNVEKGEKGSQIPLDTPQEKDSPYNMGPEAETPDTFKLPQLTTSVGHGPTPAKSLNRRFALEKNLIKVTVAPFDPTVCDVALDKDKTYVSEVTSRVTEKPSSLGEEMREDDLSPNESTLCTESEGISPDNSASDGPPLPSSNSNFQHTVSDKNMSDSKKATPVFSQILDHSETPNTGSSRRNGSYKSSFEMKLPVSSSSSKDVLDKDSGKLKVHEKRLGKVIPVLQAKTRTNVPTFSPSDLEKQKQSYLRNVIAHIEDPVDSNQGTLGELCALMDQVHHMHNQKWQHPSDLTRRNYARFRQKSLQRYSLTQWVDRNKRSHHRFQRLPDFPYGPFVSSHQQ", "length": 422 }, "evidence": [ { "id": "A0A5K1VN55", "url": "https://omabrowser.org/oma/group/A0A5K1VN55/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96BU1-1", "protein_name": "S100P-binding protein", "gene_name": "S100PBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMCSRVPSEQSSGTSLLPKDGAPFSWDSLDEDGLDDSLLELSEGEEDDGDVNYTEEEIDALLKEDDPSYEQSSGEDDGGHVEKGERGSQILLDTPREKNSSYSLGPVAETPDLFKLPQLSTSSGHGPAHTKPLNRRSVLEKNLIKVTVAPFNPTVCDALLDKDETDSSKDTEKLSSLGEEMREDGLSPNESKLCTESEGISPNNSAWNGPQLSSSNNNFQQTVSDKNMPDSENPTSVFSRISDHSETPNMELSCRNGGSHKSSCEMRSLVVSTSSNKQDVLNKDSGKMKGHERRLGKVIPVLQTKTRTNVPTFSQSNLEQQKQLYLRSVIAHIEDPEDTNQGISGELCALMDQVHHMQHSKWQHPSDLTTRNYARRQKHLQRYSLTQWVDRNMRSHHRFQRLPDFSYS", "length": 408 }, "evidence": [ { "id": "A0A5K1VN55", "url": "https://omabrowser.org/oma/group/A0A5K1VN55/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D5K4-1", "protein_name": "S100P-binding protein", "gene_name": "S100pbp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTCSLLPSEQSSGASFLPKSNASFPWGSLDEDELDDSLLEFSDGEEDDGHFSFTEEEIEMLLKDDDGGHNEYRPRKSQILPDIPQENSLYSLGPAAETPGFLKLPQLSTSVGHGPTPSKSLNRHFVLEKNLIKVTVVAPFNPTVCDPVLDKDKIDSSKETENPASLREQTREDDPQPNESKRCTEPEGVSPNTSAWDGPLLSSPSNNNIEQTASDKNIPESKKPTPVFSQISNHSEVPNRKNSGSHKSGCEVRIPVVSSSSNRHAFDKDSGEAKGERRLGKVIPVLQTRTRMFSQSELEKQKDIYLSKVIAHIEDPGDSNQGTLGELDALMDQVHMQHPDWQHPSDLTTRNYARFRQRPLQRYSLSQWVDRNKRSHHRFQRLPDFSYSPYVSSHQQ", "length": 396 }, "evidence": [ { "id": "A0A5K1VN55", "url": "https://omabrowser.org/oma/group/A0A5K1VN55/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VN55", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VN55" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VN55", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VN55" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VN55", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VN55" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VN55", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VN55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1VN55-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 419, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1VN55-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1VN55" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 132, 238 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 259, "end_pos": 261 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5K1VS40-1", "uniprot_ac": "A0A5K1VS40", "uniprot_id": "A0A5K1VS40_PIG", "mass": { "chemical_mass": 106380.0, "monoisotopic_mass": 106380.0 }, "refseq": {}, "gene_names": [ { "name": "FHIP1B", "type": "recommended", "evidence": [ { "id": "A0A5K1VS40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40" } ] } ], "protein_names": [ { "name": "FHF complex subunit HOOK-interacting protein 1B", "type": "recommended", "evidence": [ { "id": "A0A5K1VS40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40/entry#names_and_taxonomy" } ] }, { "name": "FTS- and Hook-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A5K1VS40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VS40", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40#function" }, { "database": "UniProtKB", "id": "ARBA00046048", "url": "https://www.uniprot.org/uniprotkb/ARBA00046048#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VS40", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FHIP1B", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40", "locus": { "chromosome": "9", "start_pos": 3464226, "end_pos": 3446075, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014632", "url": "https://www.ensembl.org/id/ENSSSCG00000014632" } ] } } ], "crossref": [ { "id": "A0A5K1VS40", "url": "https://alphafold.ebi.ac.uk/entry/A0A5K1VS40", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014632", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014632", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR019384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21705:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21705:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19311", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19311", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19314", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19314", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5K1VS40", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VS40-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERMNWLSRLASRGPGHRAPQGASLQTPVMADPETCLMVLKNHWSQVVRILERQGPRAAPGGADDLSAVRNHTYQMLTLLAEDRASPSAPGSGPLLEFALREDLLTRVLAWQLQWDEFGDGVEERRAEQLKLFEMLVSEARQPLLRHGPVREALLVLLDACGRPVPSSPALDEGLVLLLSQLCVCLAREPSLLEFFLQPPPEPGAAPRLLLFSRLVPFVHREGTLGQQARDALLLLMALSAGSPTVGHYIADHSYFCPVLATGLSALYSSLPRKIEVPGDDWHCLRREDWLGVPALALFLSSLEFCNAVIQVAHPLVQKQLVDYIHNGFLVPVMGPALHKTSVEEMIASTAYLELFLRSISEPALLRTFLRFLLLHRHDTHTILDTLVARIGSNSRLCMVSLSLFRTLLNLSCEDVLLQLVLRYLVPCNHVMLSQKPAVRDVDLYGRAADKFLSLIPRCCRHRAPSPPRPEHASWARGGPSREAGRREDTTGPGSPSVDSSSVVTVPRPSTPSRLALFLRQQSLGGSEAPAPAPRSPGLAASPASSPGRRPSPAEEPGELEDNYLEYLREARRGVDRCVQACRAWSAPYDGERPPPEPSPLGSRTKKRSLLAEEDGDNAGEGEEEELGGGGLAGGAREGPGHLPPPQLNGVPGPWPEGAKKVRRVPQEGAGELPEGTPEAVAGLEGFGQELRELEVALSNGGAGSEPSLEPSLPLEEEEAYESFACPPEPPGPFLSSPLRTLNQLPSQPFTGPFMAVLFAKLENMLQNSVYVNFLLTGLVAQLACHPQPLLRSFLLNTNMVFQPSVKSLLQVLGSVKNKIESFAASQEDFPALLSKAKKYLVARGKLDWTEGSAAGPAPRRSDSLVKSRRPSLGELLLRHAHSPTRARQAAQLGIQPGRDSGGLGLGGGSPGASTPVLPPRGGTPERQGEALRVKNAVYCAVIFPEFLKELAAISQAHAVTSPFLLDSSEEAPGPPVSGFGPLNP", "length": 985, "header": "tr|A0A5K1VS40-1|A0A5K1VS40_PIG Isoform 1 of FHF complex subunit HOOK-interacting protein 1B OS=Sus scrofa OX=9823 GN=FHIP1B PE=3 SV=1 CANONICAL=A0A5K1VS40-1" }, "isoforms": [ { "isoform_ac": "A0A5K1VS40-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40/entry#A0A5K1VS40-1", "sequence": { "sequence": "MERMNWLSRLASRGPGHRAPQGASLQTPVMADPETCLMVLKNHWSQVVRILERQGPRAAPGGADDLSAVRNHTYQMLTLLAEDRASPSAPGSGPLLEFALREDLLTRVLAWQLQWDEFGDGVEERRAEQLKLFEMLVSEARQPLLRHGPVREALLVLLDACGRPVPSSPALDEGLVLLLSQLCVCLAREPSLLEFFLQPPPEPGAAPRLLLFSRLVPFVHREGTLGQQARDALLLLMALSAGSPTVGHYIADHSYFCPVLATGLSALYSSLPRKIEVPGDDWHCLRREDWLGVPALALFLSSLEFCNAVIQVAHPLVQKQLVDYIHNGFLVPVMGPALHKTSVEEMIASTAYLELFLRSISEPALLRTFLRFLLLHRHDTHTILDTLVARIGSNSRLCMVSLSLFRTLLNLSCEDVLLQLVLRYLVPCNHVMLSQKPAVRDVDLYGRAADKFLSLIPRCCRHRAPSPPRPEHASWARGGPSREAGRREDTTGPGSPSVDSSSVVTVPRPSTPSRLALFLRQQSLGGSEAPAPAPRSPGLAASPASSPGRRPSPAEEPGELEDNYLEYLREARRGVDRCVQACRAWSAPYDGERPPPEPSPLGSRTKKRSLLAEEDGDNAGEGEEEELGGGGLAGGAREGPGHLPPPQLNGVPGPWPEGAKKVRRVPQEGAGELPEGTPEAVAGLEGFGQELRELEVALSNGGAGSEPSLEPSLPLEEEEAYESFACPPEPPGPFLSSPLRTLNQLPSQPFTGPFMAVLFAKLENMLQNSVYVNFLLTGLVAQLACHPQPLLRSFLLNTNMVFQPSVKSLLQVLGSVKNKIESFAASQEDFPALLSKAKKYLVARGKLDWTEGSAAGPAPRRSDSLVKSRRPSLGELLLRHAHSPTRARQAAQLGIQPGRDSGGLGLGGGSPGASTPVLPPRGGTPERQGEALRVKNAVYCAVIFPEFLKELAAISQAHAVTSPFLLDSSEEAPGPPVSGFGPLNP", "length": 985, "header": "tr|A0A5K1VS40-1|A0A5K1VS40_PIG Isoform 1 of FHF complex subunit HOOK-interacting protein 1B OS=Sus scrofa OX=9823 GN=FHIP1B PE=3 SV=1 CANONICAL=A0A5K1VS40-1" }, "locus": { "chromosome": "9", "start_pos": 3464073, "end_pos": 3451084, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035407.3", "url": "https://www.ensembl.org/id/ENSSSCT00000035407.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029765.3", "url": "https://www.ensembl.org/id/ENSSSCP00000029765.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 511, "start_aa": "Thr", "end_pos": 511, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr511", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VS40", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VS40", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VS40", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40" } ], "pmid": "" }, { "name": "lysosome organization", "id": "GO:0007040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007040", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VS40", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VS40", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40" } ], "pmid": "" }, { "name": "early endosome to late endosome transport", "id": "GO:0045022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045022", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VS40", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40" } ], "pmid": "" }, { "name": "protein localization to perinuclear region of cytoplasm", "id": "GO:1905719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905719", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VS40", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "FHF complex", "id": "GO:0070695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070695", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1VS40", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5K1VS40-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 985, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5K1VS40-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5K1VS40" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5K1VS40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS40" }, { "id": "PF19314", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19314" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FHF complex subunit HOOK-interacting protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 751, "end_pos": 843, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 511 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 410, "end_pos": 412 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5S6FZC1-1", "uniprot_ac": "A0A5S6FZC1", "uniprot_id": "A0A5S6FZC1_PIG", "mass": { "chemical_mass": 33498.0, "monoisotopic_mass": 33498.0 }, "refseq": {}, "gene_names": [ { "name": "RPL36AL", "type": "recommended", "evidence": [ { "id": "A0A5S6FZC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FZC1" } ] } ], "protein_names": [ { "name": "Ribosomal protein L36a like", "type": "synonym", "evidence": [ { "id": "A0A5S6FZC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FZC1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5S6FZC1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FZC1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPL36AL", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FZC1", "locus": { "chromosome": "1", "start_pos": 179476640, "end_pos": 179479147, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005006", "url": "https://www.ensembl.org/id/ENSSSCG00000005006" } ] } } ], "crossref": [ { "id": "A0A5S6FZC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A5S6FZC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005006", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005006", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000552", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000552", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053708", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053708", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00935", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00935", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5S6FZC1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FZC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5S6FZC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FZC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LIPGPGGPGARRRSAPLCRPGSTHPRLAAAAQAVPPLGAATQRRLGPLHPARVREARRGPTAPRLRYLRFQRPCVLWAFILTQAPDVPDRGTQPRPTPAETVLTTSNWLAELRGPRAHTPPARPSGRRLALPRRVGRRPGVAARLLLGRGAVAQAQFLLPSRSSFSGEARAERDPERGHRFYCIHRENTPVAKMVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 299, "header": "tr|A0A5S6FZC1-1|A0A5S6FZC1_PIG Isoform 1 of Ribosomal protein L36a like OS=Sus scrofa OX=9823 GN=RPL36AL PE=3 SV=1 CANONICAL=A0A5S6FZC1-1" }, "isoforms": [ { "isoform_ac": "A0A5S6FZC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FZC1/entry#A0A5S6FZC1-1", "sequence": { "sequence": "LIPGPGGPGARRRSAPLCRPGSTHPRLAAAAQAVPPLGAATQRRLGPLHPARVREARRGPTAPRLRYLRFQRPCVLWAFILTQAPDVPDRGTQPRPTPAETVLTTSNWLAELRGPRAHTPPARPSGRRLALPRRVGRRPGVAARLLLGRGAVAQAQFLLPSRSSFSGEARAERDPERGHRFYCIHRENTPVAKMVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 299, "header": "tr|A0A5S6FZC1-1|A0A5S6FZC1_PIG Isoform 1 of Ribosomal protein L36a like OS=Sus scrofa OX=9823 GN=RPL36AL PE=3 SV=1 CANONICAL=A0A5S6FZC1-1" }, "locus": { "chromosome": "1", "start_pos": 179478337, "end_pos": 179476738, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005522.4", "url": "https://www.ensembl.org/id/ENSSSCT00000005522.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005385.3", "url": "https://www.ensembl.org/id/ENSSSCP00000005385.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 61, "start_aa": "Thr", "end_pos": 61, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr61", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 97, "start_aa": "Thr", "end_pos": 97, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr97", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6FZC1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FZC1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6FZC1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FZC1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6FZC1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FZC1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6FZC1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6FZC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5S6FZC1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 299, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5S6FZC1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5S6FZC1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 61, 97 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5S6G9F8-1", "uniprot_ac": "A0A5S6G9F8", "uniprot_id": "A0A5S6G9F8_PIG", "mass": { "chemical_mass": 23059.0, "monoisotopic_mass": 23059.0 }, "refseq": {}, "gene_names": [ { "name": "SPCS1", "type": "recommended", "evidence": [ { "id": "A0A5S6G9F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8" } ] } ], "protein_names": [ { "name": "Signal peptidase complex subunit 1", "type": "recommended", "evidence": [ { "id": "A0A5S6G9F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8/entry#names_and_taxonomy" } ] }, { "name": "Microsomal signal peptidase 12 kDa subunit", "type": "synonym", "evidence": [ { "id": "A0A5S6G9F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Dispensable for SPC enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8#function" }, { "database": "UniProtKB", "id": "ARBA00045204", "url": "https://www.uniprot.org/uniprotkb/ARBA00045204#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5S6G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SPCS1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8", "locus": { "chromosome": "13", "start_pos": 34841600, "end_pos": 34839384, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011447", "url": "https://www.ensembl.org/id/ENSSSCG00000011447" } ] } } ], "crossref": [ { "id": "A0A5S6G9F8", "url": "https://alphafold.ebi.ac.uk/entry/A0A5S6G9F8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011447", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011447", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR009542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13202", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13202", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13202:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13202:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-422085", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-422085", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9768727", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9768727", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5S6G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5S6G9F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "FGGPEPRLPARNSTDGEPLTGARCLDSSATVSISALADRGPAYSQLRKCGSLRETGGGALGCPSLQETSASGAVAVVTSGSAGLLSCTKLTQVPTVPESRPPSLRRPLPEPVMLEHLSSLPTQMDYKGQKLAEQMFQGIILFSAIVGFIYGYVAEQFGWTVYIVMAGFAFSCLLTLPPWPIYRRHPLKWLPVQDSGTEDKKPGERKIKRHAKNN", "length": 214, "header": "tr|A0A5S6G9F8-1|A0A5S6G9F8_PIG Isoform 1 of Signal peptidase complex subunit 1 OS=Sus scrofa OX=9823 GN=SPCS1 PE=3 SV=1 CANONICAL=A0A5S6G9F8-1" }, "isoforms": [ { "isoform_ac": "A0A5S6G9F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8/entry#A0A5S6G9F8-1", "sequence": { "sequence": "FGGPEPRLPARNSTDGEPLTGARCLDSSATVSISALADRGPAYSQLRKCGSLRETGGGALGCPSLQETSASGAVAVVTSGSAGLLSCTKLTQVPTVPESRPPSLRRPLPEPVMLEHLSSLPTQMDYKGQKLAEQMFQGIILFSAIVGFIYGYVAEQFGWTVYIVMAGFAFSCLLTLPPWPIYRRHPLKWLPVQDSGTEDKKPGERKIKRHAKNN", "length": 214, "header": "tr|A0A5S6G9F8-1|A0A5S6G9F8_PIG Isoform 1 of Signal peptidase complex subunit 1 OS=Sus scrofa OX=9823 GN=SPCS1 PE=3 SV=1 CANONICAL=A0A5S6G9F8-1" }, "locus": { "chromosome": "13", "start_pos": 34841241, "end_pos": 34839668, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012527.4", "url": "https://www.ensembl.org/id/ENSSSCT00000012527.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012199.2", "url": "https://www.ensembl.org/id/ENSSSCP00000012199.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-422085", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-422085", "resource": "Reactome", "description": "Synthesis, secretion, and deacylation of Ghrelin" }, { "id": "R-SSC-9768727", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9768727", "resource": "Reactome", "description": "Regulation of CDH1 posttranslational processing and trafficking to plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein targeting to ER", "id": "GO:0045047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045047", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8" } ], "pmid": "" }, { "name": "signal peptide processing", "id": "GO:0006465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006465", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "signal peptidase complex", "id": "GO:0005787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005787", "evidence": [ { "database": "UniProtKB", "id": "A0A5S6G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A5S6G9F8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5S6G9F8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 214, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5S6G9F8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5S6G9F8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SVF9-1", "uniprot_ac": "A0A4X1SVF9", "uniprot_id": "A0A4X1SVF9_PIG", "mass": { "chemical_mass": 93179.0, "monoisotopic_mass": 93179.0 }, "refseq": { "ac": "NP_001193276", "name": "periostin isoform 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193276" }, "gene_names": [ { "name": "POSTN", "type": "recommended", "evidence": [ { "id": "A0A4X1SVF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" } ] }, { "name": "POSTN", "type": "synonym", "evidence": [ { "id": "NP_001193276", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193276" } ] } ], "protein_names": [ { "name": "Periostin", "type": "recommended", "evidence": [ { "id": "A0A4X1SVF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9/entry#names_and_taxonomy" } ] }, { "name": "Osteoblast-specific factor 2", "type": "synonym", "evidence": [ { "id": "A0A4X1SVF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9/entry#names_and_taxonomy" } ] }, { "name": "periostin isoform 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001193276", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193276" } ] }, { "name": "periostin, osteoblast specific factor", "type": "synonym", "evidence": [ { "id": "NP_001193276", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193276" } ] } ], "function": [ { "annotation": "Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYP9#function" }, { "database": "UniProtKB", "id": "ARBA00058492", "url": "https://www.uniprot.org/uniprotkb/ARBA00058492#function" }, { "database": "UniProtKB", "id": "I3LDM1", "url": "https://www.uniprot.org/uniprotkb/I3LDM1#function" }, { "database": "UniProtKB", "id": "A0A286ZN21", "url": "https://www.uniprot.org/uniprotkb/A0A286ZN21#function" }, { "database": "UniProtKB", "id": "A0A8D1XYX0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XYX0#function" }, { "database": "UniProtKB", "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9#function" }, { "database": "UniProtKB", "id": "A0A5G2QPN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPN2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "POSTN", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9", "locus": { "chromosome": "11", "start_pos": 13224959, "end_pos": 13258978, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009361", "url": "https://www.ensembl.org/id/ENSSSCG00000009361" } ] } } ], "crossref": [ { "id": "A0A4X1SVF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SVF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009361", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009361", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152401", "url": "https://www.ncbi.nlm.nih.gov/gene/100152401", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152401", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152401", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SVF9", "url": "https://www.orthodb.org/?gene=A0A4X1SVF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "I3LDM1", "url": "https://www.orthodb.org/?gene=I3LDM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10900", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10900", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10900:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10900:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193276", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193276", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZN21", "url": "https://www.uniprot.org/uniprotkb/A0A286ZN21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZN21-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZN21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SVF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYP9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1XYX0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XYX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1XYX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XYX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LDM1", "url": "https://www.uniprot.org/uniprotkb/I3LDM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LDM1-1", "url": "https://www.uniprot.org/uniprotkb/I3LDM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIPFLPVFSLFLLVVVNPANANGHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYQGAICGKKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDVSKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMVNKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILESLGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITSGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGNQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQKLETIGGKQLRVFVYRTAVCIENSCMVRGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSIFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTNEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIYLKGVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADIPVGNDQLLEILNKLIKYIQIKFVRGSTFKEIPITVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPMITKVKIEGEPELRLVKEGETVTEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTSGGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKIQATKRVQGSRRRSREDRPQ", "length": 836, "header": "tr|A0A4X1SVF9-1|A0A4X1SVF9_PIG Isoform 1 of Periostin OS=Sus scrofa OX=9823 GN=POSTN PE=1 SV=1 CANONICAL=A0A4X1SVF9-1" }, "isoforms": [ { "isoform_ac": "A0A286ZN21-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9/entry#A0A286ZN21-1", "sequence": { "sequence": "MIPFLPVFSLFLLVVVNPANANGHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYQGAICGKKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDVSKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMVNKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILESLGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITSGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQKLETIGGKQLRVFVYRTAVCIENSCMVRGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSIFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTNEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIYLKGVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADIPVGNDQLLEILNKLIKYIQIKFVRGSTFKEIPITVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPMITKVKIEGEPELRLVKEGETVTEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTSGGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKIQATKRVQGSRRRSREDRPQ", "length": 791, "header": "tr|A0A286ZN21-1|A0A4X1SVF9_PIG Computationally mapped isoform of Periostin OS=Sus scrofa OX=9823 GN=POSTN PE=1 SV=2 CANONICAL=A0A4X1SVF9-1" }, "locus": { "chromosome": "11", "start_pos": 13258844, "end_pos": 13225955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050600.2", "url": "https://www.ensembl.org/id/ENSSSCT00000050600.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032975.2", "url": "https://www.ensembl.org/id/ENSSSCP00000032975.2" } ] } }, { "isoform_ac": "A0A4X1SVF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9/entry#A0A4X1SVF9-1", "sequence": { "sequence": "MIPFLPVFSLFLLVVVNPANANGHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYQGAICGKKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDVSKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMVNKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILESLGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITSGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGNQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQKLETIGGKQLRVFVYRTAVCIENSCMVRGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSIFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTNEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIYLKGVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADIPVGNDQLLEILNKLIKYIQIKFVRGSTFKEIPITVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPMITKVKIEGEPELRLVKEGETVTEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTSGGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKIQATKRVQGSRRRSREDRPQ", "length": 836, "header": "tr|A0A4X1SVF9-1|A0A4X1SVF9_PIG Isoform 1 of Periostin OS=Sus scrofa OX=9823 GN=POSTN PE=1 SV=1 CANONICAL=A0A4X1SVF9-1" }, "locus": { "chromosome": "11", "start_pos": 13258844, "end_pos": 13225955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010258.4", "url": "https://www.ensembl.org/id/ENSSSCT00000010258.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009991.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009991.2" } ] } }, { "isoform_ac": "A0A5G2QPN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9/entry#A0A5G2QPN2-1", "sequence": { "sequence": "MIPFLPVFSLFLLVVVNPANANGHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYQGAICGKKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDVSKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMVNKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILESLGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITSGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGNQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQKLETIGGKQLRVFVYRTAVCIENSCMVRGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSIFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTNEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIYLKGVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADIPVGNDQLLEILNKLIKYIQIKFVRGSTFKEIPITVYSKYIMNICHI", "length": 679, "header": "tr|A0A5G2QPN2-1|A0A4X1SVF9_PIG Computationally mapped isoform of Periostin OS=Sus scrofa OX=9823 GN=POSTN PE=1 SV=1 CANONICAL=A0A4X1SVF9-1" }, "locus": { "chromosome": "11", "start_pos": 13258844, "end_pos": 13240152, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087159.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087159.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066865.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066865.1" } ] } }, { "isoform_ac": "A0A5G2QYP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9/entry#A0A5G2QYP9-1", "sequence": { "sequence": "MIPFLPVFSLFLLVVVNPANANGHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYQGAICGKKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDVSKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMVNKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILESLGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITSGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGNQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQKLETIGGKQLRVFVYRTAVCIENSCMVRGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSIFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTNEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIYLKGVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADIPVGNDQLLEILNKLIKYIQIKFVRGSTFKEIPITVYRPMITKVKIEGEPELRLVKEGETVTEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTSGGETEETLKKLLQEAL", "length": 757, "header": "tr|A0A5G2QYP9-1|A0A4X1SVF9_PIG Computationally mapped isoform of Periostin OS=Sus scrofa OX=9823 GN=POSTN PE=1 SV=1 CANONICAL=A0A4X1SVF9-1" }, "locus": { "chromosome": "11", "start_pos": 13258844, "end_pos": 13229858, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084601.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084601.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063350.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063350.1" } ] } }, { "isoform_ac": "A0A8D1XYX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9/entry#A0A8D1XYX0-1", "sequence": { "sequence": "MIPFLPVFSLFLLVVVNPANANGHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYQGAICGKKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDVSKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMVNKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILESLGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITSGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGNQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQKLETIGGKQLRVFVYRTAVCIENSCMVRGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSIFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTNEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIYLKGVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADIPVGNDQLLEILNKLIKYIQIKFVRGSTFKEIPITVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPMITKVKIEGEPELRLVKEGETVTEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTSGGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQGGSTFKRKEEKKNSKS", "length": 825, "header": "tr|A0A8D1XYX0-1|A0A4X1SVF9_PIG Computationally mapped isoform of Periostin OS=Sus scrofa OX=9823 GN=POSTN PE=1 SV=1 CANONICAL=A0A4X1SVF9-1" }, "locus": { "chromosome": "11", "start_pos": 13258844, "end_pos": 13231007, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064106.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064106.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050106.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050106.2" } ] } }, { "isoform_ac": "I3LDM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9/entry#I3LDM1-1", "sequence": { "sequence": "MIPFLPVFSLFLLVVVNPANANGHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYQGAICGKKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDVSKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMVNKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILESLGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITSGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGNQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQKLETIGGKQLRVFVYRTAVCIENSCMVRGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSIFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTNEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIYLKGVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADIPVGNDQLLEILNKLIKYIQIKFVRGSTFKEIPITVYRPMITKVKIEGEPELRLVKEGETVTEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTSGGETEETLKKLLQEDTPVRKIQATKRVQGSRRRSREDRPQ", "length": 781, "header": "tr|I3LDM1-1|A0A4X1SVF9_PIG Computationally mapped isoform of Periostin OS=Sus scrofa OX=9823 GN=POSTN PE=1 SV=1 CANONICAL=A0A4X1SVF9-1" }, "locus": { "chromosome": "11", "start_pos": 13258844, "end_pos": 13225955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022465.4", "url": "https://www.ensembl.org/id/ENSSSCT00000022465.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022153.1", "url": "https://www.ensembl.org/id/ENSSSCP00000022153.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPN2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPN2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152401", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152401", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cellular response to vitamin K", "id": "GO:0071307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071307", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 599, "end_pos": 601, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SVF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" }, { "id": "PS51041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EMI", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 94, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SVF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVF9" }, { "id": "PS50213", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50213" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAS1", "eco_id": "ECO_0000259", "start_pos": 97, "end_pos": 230, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 599, "end_pos": 601 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SI63-1", "uniprot_ac": "A0A4X1SI63", "uniprot_id": "A0A4X1SI63_PIG", "mass": { "chemical_mass": 25615.0, "monoisotopic_mass": 25615.0 }, "refseq": { "ac": "NP_001231302", "name": "peroxiredoxin-like 2A isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231302" }, "gene_names": [ { "name": "PRXL2A", "type": "recommended", "evidence": [ { "id": "A0A4X1SI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63" } ] }, { "name": "C10orf58", "type": "synonym", "evidence": [ { "id": "NP_001231302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231302" } ] }, { "name": "C14H10orf58", "type": "synonym", "evidence": [ { "id": "NP_001231302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231302" } ] }, { "name": "FAM213A", "type": "synonym", "evidence": [ { "id": "NP_001231302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231302" } ] }, { "name": "PRXL2A", "type": "synonym", "evidence": [ { "id": "NP_001231302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231302" } ] }, { "name": "SFLQ611", "type": "synonym", "evidence": [ { "id": "NP_001231302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231302" } ] } ], "protein_names": [ { "name": "Peroxiredoxin-like 2A", "type": "recommended", "evidence": [ { "id": "A0A4X1SI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63/entry#names_and_taxonomy" } ] }, { "name": "Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes", "type": "synonym", "evidence": [ { "id": "A0A4X1SI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63/entry#names_and_taxonomy" } ] }, { "name": "Redox-regulatory protein FAM213A", "type": "synonym", "evidence": [ { "id": "A0A4X1SI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63/entry#names_and_taxonomy" } ] }, { "name": "family with sequence similarity 213 member A", "type": "synonym", "evidence": [ { "id": "NP_001231302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231302" } ] }, { "name": "peroxiredoxin-like 2A isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001231302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231302" } ] } ], "function": [ { "annotation": "Involved in redox regulation of the cell. Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SI63", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63#function" }, { "database": "UniProtKB", "id": "ARBA00059103", "url": "https://www.uniprot.org/uniprotkb/ARBA00059103#function" }, { "database": "UniProtKB", "id": "A0A287ACV7", "url": "https://www.uniprot.org/uniprotkb/A0A287ACV7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SI63", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PRXL2A", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63", "locus": { "chromosome": "14", "start_pos": 82271214, "end_pos": 82249452, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010340", "url": "https://www.ensembl.org/id/ENSSSCG00000010340" } ] } } ], "crossref": [ { "id": "A0A4X1SI63", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SI63", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010340", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010340", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02970", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02970", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155717", "url": "https://www.ncbi.nlm.nih.gov/gene/100155717", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155717", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155717", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287ACV7", "url": "https://www.orthodb.org/?gene=A0A287ACV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SI63", "url": "https://www.orthodb.org/?gene=A0A4X1SI63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28630", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28630", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28630:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28630:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13911", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13911", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231302", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287ACV7", "url": "https://www.uniprot.org/uniprotkb/A0A287ACV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ACV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ACV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SI63", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SI63-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FK04", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FK04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FK04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FK04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFLQDPSFVTMGMWSIGAGAIGAAALALLLANTDIFLPKPQRATLDYLEDIDLKTLEKEPKTFKAKALWEKTGAVIMAVRRPGCFLCREEAADLSSLKPRLDELGVPLYAVVKEQVKNEVKDFQPYFKGEIFLDEEKKFYGPQRRKMMFMGFVRLGVWYNFFRARSGGFSGNLEGEGFVLGGVFVVGPGKQGILLEHREKEFGDKVNPVSVLEAVRKIKPHTSASEKK", "length": 229, "header": "tr|A0A4X1SI63-1|A0A4X1SI63_PIG Isoform 1 of Peroxiredoxin-like 2A OS=Sus scrofa OX=9823 GN=PRXL2A PE=1 SV=1 CANONICAL=A0A4X1SI63-1" }, "isoforms": [ { "isoform_ac": "A0A287ACV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63/entry#A0A287ACV7-1", "sequence": { "sequence": "MGMWSIGAGAIGAAALALLLANTDIFLPKPQRATLDYLEDIDLKTLEKEPKTFKAKALWEKTGAVIMAVRRPGCFLCREEAADLSSLKPRLDELGVPLYAVVKEQVKNEVKDFQPYFKGEIFLDEEKKFYGPQRRKMMFMGFVRLGVWYNFFRARSGGFSGNLEGEGFVLGGVFVVGPGKQGILLEHREKEFGDKVNPVSVLEAVRKIKPHTSASEKK", "length": 218, "header": "tr|A0A287ACV7-1|A0A4X1SI63_PIG Computationally mapped isoform of Peroxiredoxin-like 2A OS=Sus scrofa OX=9823 GN=PRXL2A PE=1 SV=1 CANONICAL=A0A4X1SI63-1" }, "locus": { "chromosome": "14", "start_pos": 82270580, "end_pos": 82261925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062410.2", "url": "https://www.ensembl.org/id/ENSSSCT00000062410.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041838.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041838.1" } ] } }, { "isoform_ac": "A0A4X1SI63-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63/entry#A0A4X1SI63-1", "sequence": { "sequence": "MSFLQDPSFVTMGMWSIGAGAIGAAALALLLANTDIFLPKPQRATLDYLEDIDLKTLEKEPKTFKAKALWEKTGAVIMAVRRPGCFLCREEAADLSSLKPRLDELGVPLYAVVKEQVKNEVKDFQPYFKGEIFLDEEKKFYGPQRRKMMFMGFVRLGVWYNFFRARSGGFSGNLEGEGFVLGGVFVVGPGKQGILLEHREKEFGDKVNPVSVLEAVRKIKPHTSASEKK", "length": 229, "header": "tr|A0A4X1SI63-1|A0A4X1SI63_PIG Isoform 1 of Peroxiredoxin-like 2A OS=Sus scrofa OX=9823 GN=PRXL2A PE=1 SV=1 CANONICAL=A0A4X1SI63-1" }, "locus": { "chromosome": "14", "start_pos": 82270580, "end_pos": 82261892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055715.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055715.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053450.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053450.1" } ] } }, { "isoform_ac": "A0A8W4FK04-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63/entry#A0A8W4FK04-1", "sequence": { "sequence": "MAVRRPGCFLCREEAADLSSLKPRLDELGVPLYAVVKEQVKNEVKDFQPYFKGEIFLDEEGILLEHREKEFGDKVNPVSVLEAVRKIKPHTSASEKK", "length": 97, "header": "tr|A0A8W4FK04-1|A0A4X1SI63_PIG Computationally mapped isoform of Peroxiredoxin-like 2A OS=Sus scrofa OX=9823 GN=PRXL2A PE=1 SV=1 CANONICAL=A0A4X1SI63-1" }, "locus": { "chromosome": "14", "start_pos": 82270580, "end_pos": 82263901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096281.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096281.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078640.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078640.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FK04", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FK04" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155717", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155717", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SI63", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "antioxidant activity", "id": "GO:0016209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016209", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SI63", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of osteoclast differentiation", "id": "GO:0045670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045670", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SI63", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SI63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SPN2-1", "uniprot_ac": "A0A4X1SPN2", "uniprot_id": "A0A4X1SPN2_PIG", "mass": { "chemical_mass": 46119.0, "monoisotopic_mass": 46119.0 }, "refseq": { "ac": "XP_005670298", "name": "HERV-H LTR-associating protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670298" }, "gene_names": [ { "name": "HHLA2", "type": "recommended", "evidence": [ { "id": "A0A4X1SPN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" } ] }, { "name": "HHLA2", "type": "synonym", "evidence": [ { "id": "XP_005670298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670298" } ] } ], "protein_names": [ { "name": "HERV-H LTR-associating protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005670298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670298" } ] }, { "name": "HHLA2 member of B7 family", "type": "synonym", "evidence": [ { "id": "A0A4X1SPN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HHLA2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2", "locus": { "chromosome": "13", "start_pos": 151156800, "end_pos": 151298330, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027275", "url": "https://www.ensembl.org/id/ENSSSCG00000027275" } ] } } ], "crossref": [ { "id": "A0A4X1SPN2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SPN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000027275", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027275", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "102166962", "url": "https://www.ncbi.nlm.nih.gov/gene/102166962", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:102166962", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102166962", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AF24", "url": "https://www.orthodb.org/?gene=A0A287AF24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SPN2", "url": "https://www.orthodb.org/?gene=A0A4X1SPN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25466", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25466", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25466:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25466:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005670298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670298", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AF24", "url": "https://www.uniprot.org/uniprotkb/A0A287AF24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AF24-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AF24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SPN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SPN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAQAVLSFFFTLIPSLCGSQDTFFLASFSPLSTMSEQVVIGRLDEDVILPCSFESGPDIVIHWKNQDNYYLYSYYKESDQLEKQDPKFINRTSLFHGQIHNGNASLSFRRLSLQDEGIYVCYVGTSSRKKINKVVLKVGAFVTPVMKYEKKNTNSFLICNVLSVYPYPIITWKVDDTPISENSVEEVESLGAFCINSGVNITRSNSSYQCAIENTLLKQTWRGKWTMKDGFRKMQSENVLLSCEPENSFFLPTQDFVVTWSKVGSETSSVLAYFLNSSQKTVVNEPRLSWNKELINRHNFSLTLKDLSLSDSGEYLCNISSSNYTLLTIQTLHVEVDQRTVVRIILPILVAVLAATLVLSVVTSKLRRCICSCPEEHSTNQRSCNAGTAEETRALSDHPASIRNEGRS", "length": 409, "header": "tr|A0A4X1SPN2-1|A0A4X1SPN2_PIG Isoform 1 of HHLA2 member of B7 family OS=Sus scrofa OX=9823 GN=HHLA2 PE=4 SV=1 CANONICAL=A0A4X1SPN2-1" }, "isoforms": [ { "isoform_ac": "A0A287AF24-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2/entry#A0A287AF24-1", "sequence": { "sequence": "MKAQAVLSFFFTLIPSLCGSQDTFFLASFSPLSTMSEQVVIGRLDEDVILPCSFESGPDIVIHWKNQDNYYLYSYYKESDQLEKQDPKFINRTSLFHGQIHNGNASLSFRRLSLQDEGIYVCYVGTSSRKKINKVVLKVGAFVTPVMKYEKKNTNSFLICNVLSVYPYPIITWKVDDTPISENSVEEVESLGAFCINSGVNITRSNSSYQCAIENTLLKQTWRGKWTMKDFVVTWSKVGSETSSVLAYFLNSSQKTVVNEPRLSWNKELINRHNFSLTLKDLSLSDSGEYLCNISSSNYTLLTIQTLHVEVDQRTVVRIILPILVAVLAATLVLSVVTSKLRRCICSCPEEHSTNQRSCNAGTAEETRALSDHPASIRNEGRS", "length": 383, "header": "tr|A0A287AF24-1|A0A4X1SPN2_PIG Computationally mapped isoform of HHLA2 member of B7 family OS=Sus scrofa OX=9823 GN=HHLA2 PE=4 SV=2 CANONICAL=A0A4X1SPN2-1" }, "locus": { "chromosome": "13", "start_pos": 151177558, "end_pos": 151159352, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058172.2", "url": "https://www.ensembl.org/id/ENSSSCT00000058172.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042429.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042429.2" } ] } }, { "isoform_ac": "A0A4X1SPN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2/entry#A0A4X1SPN2-1", "sequence": { "sequence": "MKAQAVLSFFFTLIPSLCGSQDTFFLASFSPLSTMSEQVVIGRLDEDVILPCSFESGPDIVIHWKNQDNYYLYSYYKESDQLEKQDPKFINRTSLFHGQIHNGNASLSFRRLSLQDEGIYVCYVGTSSRKKINKVVLKVGAFVTPVMKYEKKNTNSFLICNVLSVYPYPIITWKVDDTPISENSVEEVESLGAFCINSGVNITRSNSSYQCAIENTLLKQTWRGKWTMKDGFRKMQSENVLLSCEPENSFFLPTQDFVVTWSKVGSETSSVLAYFLNSSQKTVVNEPRLSWNKELINRHNFSLTLKDLSLSDSGEYLCNISSSNYTLLTIQTLHVEVDQRTVVRIILPILVAVLAATLVLSVVTSKLRRCICSCPEEHSTNQRSCNAGTAEETRALSDHPASIRNEGRS", "length": 409, "header": "tr|A0A4X1SPN2-1|A0A4X1SPN2_PIG Isoform 1 of HHLA2 member of B7 family OS=Sus scrofa OX=9823 GN=HHLA2 PE=4 SV=1 CANONICAL=A0A4X1SPN2-1" }, "locus": { "chromosome": "13", "start_pos": 151177558, "end_pos": 151159352, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024843.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024843.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020031.4", "url": "https://www.ensembl.org/id/ENSSSCP00000020031.4" } ] } }, { "isoform_ac": "A0A5G2RDM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2/entry#A0A5G2RDM5-1", "sequence": { "sequence": "MKAQAVLSFFFTLIPSLCGSQDTFFLASFSPLSTMSEQVVIGRLDEDVILPCSFESGPDIVIHWKNQDNYYLYSYYKESDQLEKQDPKFINRTSLFHGQIHNGNASLSFRRLSLQDEGIYVCYVGTSSRKKINKVVLKVGAFVTPVMKYEKKNTNSFLICNVLSVYPYPIITWKVDDTPISENSVEEVESLGAFCINSGVNITRSNSSYQCAIENTLLKQTWRGKWTMKDFVVTWSKVGSETSSVLAYFLNSSQKTVVNEPRLSWNKELINRHNFSLTLKDLSLSDSGEYLCNISSSNYTLLTIQTLHVEVDQRTVVRIILPILVAVLAATLVLSVVTSKLRRCICSCPEEHSTNQRSCNAGTAEETRVRHFLYHL", "length": 376, "header": "tr|A0A5G2RDM5-1|A0A4X1SPN2_PIG Computationally mapped isoform of HHLA2 member of B7 family OS=Sus scrofa OX=9823 GN=HHLA2 PE=4 SV=2 CANONICAL=A0A4X1SPN2-1" }, "locus": { "chromosome": "13", "start_pos": 151177558, "end_pos": 151160154, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071915.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071915.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072515.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072515.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RDM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDM5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102166962", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102166962", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "regulation of T cell activation", "id": "GO:0050863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050863", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" } ], "pmid": "" }, { "name": "regulation of leukocyte cell-cell adhesion", "id": "GO:1903037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903037", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" } ], "pmid": "" }, { "name": "T cell costimulation", "id": "GO:0031295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031295", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" } ], "pmid": "" }, { "name": "positive regulation of cytokine production", "id": "GO:0001819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001819", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" } ], "pmid": "" }, { "name": "positive regulation of activated T cell proliferation", "id": "GO:0042104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042104", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SPN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPN2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 133, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 206, "end_pos": 208 }, { "start_pos": 277, "end_pos": 279 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T764-1", "uniprot_ac": "A0A4X1T764", "uniprot_id": "A0A4X1T764_PIG", "mass": { "chemical_mass": 10072.0, "monoisotopic_mass": 10072.0 }, "refseq": { "ac": "XP_003130588", "name": "signal recognition particle 9 kDa protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130588" }, "gene_names": [ { "name": "SRP9", "type": "recommended", "evidence": [ { "id": "A0A4X1T764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764" } ] }, { "name": "SRP9", "type": "synonym", "evidence": [ { "id": "XP_003130588", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130588" } ] } ], "protein_names": [ { "name": "Signal recognition particle 9 kDa protein", "type": "recommended", "evidence": [ { "id": "A0A4X1T764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764/entry#names_and_taxonomy" } ] }, { "name": "SRP9", "type": "synonym", "evidence": [ { "id": "A0A4X1T764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764/entry#names_and_taxonomy" } ] }, { "name": "signal recognition particle 9 kDa protein", "type": "synonym", "evidence": [ { "id": "XP_003130588", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130588" } ] } ], "function": [ { "annotation": "Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F6X7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6X7#function" }, { "database": "UniProtKB", "id": "ARBA00045462", "url": "https://www.uniprot.org/uniprotkb/ARBA00045462#function" }, { "database": "UniProtKB", "id": "A0A4X1T764", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764#function" }, { "database": "UniProtKB", "id": "PIRNR017029", "url": "https://www.uniprot.org/uniprotkb/PIRNR017029#function" }, { "database": "UniProtKB", "id": "A0A287AJ59", "url": "https://www.uniprot.org/uniprotkb/A0A287AJ59#function" }, { "database": "UniProtKB", "id": "A0A4X1T769", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T769#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T764", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SRP9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764", "locus": { "chromosome": "10", "start_pos": 13723800, "end_pos": 13672355, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031664", "url": "https://www.ensembl.org/id/ENSSSCG00000031664" } ] } } ], "crossref": [ { "id": "A0A4X1T764", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T764", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000031664", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031664", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100524270", "url": "https://www.ncbi.nlm.nih.gov/gene/100524270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039432", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039432", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524270", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524270", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YYQVWEE", "url": "https://omabrowser.org/oma/group/YYQVWEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T764", "url": "https://www.orthodb.org/?gene=A0A4X1T764", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12834", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12834", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12834:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12834:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05486", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05486", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003130588", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130588", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AJ59", "url": "https://www.uniprot.org/uniprotkb/A0A287AJ59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AJ59-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJ59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T764", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T764-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T769", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T769", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T769-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T769-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6X7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6X7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGSLCIKVTDDLVCLVYRTDQAQDVKKIEKFHSQLMRLMVAKESRSVAMETD", "length": 86, "header": "tr|A0A4X1T764-1|A0A4X1T764_PIG Isoform 1 of Signal recognition particle 9 kDa protein OS=Sus scrofa OX=9823 GN=SRP9 PE=3 SV=1 CANONICAL=A0A4X1T764-1" }, "isoforms": [ { "isoform_ac": "A0A287AJ59-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764/entry#A0A287AJ59-1", "sequence": { "sequence": "MPQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGSLCIKVTDDLVQWHLNSYKMLNLRNVIAGGLET", "length": 69, "header": "tr|A0A287AJ59-1|A0A4X1T764_PIG Computationally mapped isoform of Signal recognition particle 9 kDa protein OS=Sus scrofa OX=9823 GN=SRP9 PE=3 SV=2 CANONICAL=A0A4X1T764-1" }, "locus": { "chromosome": "10", "start_pos": 13722465, "end_pos": 13711690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052758.2", "url": "https://www.ensembl.org/id/ENSSSCT00000052758.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043926.2", "url": "https://www.ensembl.org/id/ENSSSCP00000043926.2" } ] } }, { "isoform_ac": "A0A4X1T764-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764/entry#A0A4X1T764-1", "sequence": { "sequence": "MPQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGSLCIKVTDDLVCLVYRTDQAQDVKKIEKFHSQLMRLMVAKESRSVAMETD", "length": 86, "header": "tr|A0A4X1T764-1|A0A4X1T764_PIG Isoform 1 of Signal recognition particle 9 kDa protein OS=Sus scrofa OX=9823 GN=SRP9 PE=3 SV=1 CANONICAL=A0A4X1T764-1" }, "locus": { "chromosome": "10", "start_pos": 13722734, "end_pos": 13711690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105011.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105011.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076922.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076922.1" } ] } }, { "isoform_ac": "A0A4X1T769-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764/entry#A0A4X1T769-1", "sequence": { "sequence": "MPQYQTWEEFSRAAEKLYLADPMKCLVYRTDQAQDVKKIEKFHSQLMRLMVAKESRSVAMETD", "length": 63, "header": "tr|A0A4X1T769-1|A0A4X1T769_PIG Computationally mapped isoform of Signal recognition particle 9 OS=Sus scrofa OX=9823 GN=SRP9 PE=4 SV=1 CANONICAL=A0A4X1T764-1" }, "locus": { "chromosome": "10", "start_pos": 13722734, "end_pos": 13711690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073190.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073190.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067405.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067405.1" } ] } }, { "isoform_ac": "A0A8W4F6X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764/entry#A0A8W4F6X7-1", "sequence": { "sequence": "MPQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGSLCIKVTDDLVTKLKM", "length": 52, "header": "tr|A0A8W4F6X7-1|A0A4X1T764_PIG Computationally mapped isoform of Signal recognition particle 9 kDa protein OS=Sus scrofa OX=9823 GN=SRP9 PE=3 SV=1 CANONICAL=A0A4X1T764-1" }, "locus": { "chromosome": "10", "start_pos": 13722651, "end_pos": 13711690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104970.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104970.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074970.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074970.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F6X7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6X7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524270", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524270", "resource": "KEGG Pathway" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A511-1", "protein_name": "Signal recognition particle 9 kDa protein", "gene_name": "Srp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQFQTWEEFSRAAEKLYLADPMKVRVVLKYRHVDGNLCIKVTDDLVCLVYRTDQAQDVKKIEKFHSQLMRLMVAKESRSVAMETE", "length": 86 }, "evidence": [ { "id": "A0A4X1T764", "url": "https://omabrowser.org/oma/group/A0A4X1T764/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P49458-1", "protein_name": "Signal recognition particle 9 kDa protein", "gene_name": "SRP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGNLCVKVTDDLVCLVYKTDQAQDVKKIEKFHSQLMRLMVAKEARNVTMETE", "length": 86 }, "evidence": [ { "id": "A0A4X1T764", "url": "https://omabrowser.org/oma/group/A0A4X1T764/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49962-1", "protein_name": "Signal recognition particle 9 kDa protein", "gene_name": "Srp9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPQFQTWEEFSRAAEKLYLADPMKVRVVLKYRHVDGNLCIKVTDDLVCLVYRTDQAQDVKKIEKFHSQLMRLMVAKESRNVTMETE", "length": 86 }, "evidence": [ { "id": "A0A4X1T764", "url": "https://omabrowser.org/oma/group/A0A4X1T764/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "signal recognition particle, endoplasmic reticulum targeting", "id": "GO:0005786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005786", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T764", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T764", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T764", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764" } ], "pmid": "" }, { "name": "negative regulation of translational elongation", "id": "GO:0045900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045900", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T764", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "7S RNA binding", "id": "GO:0008312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008312", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T764", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T764" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SR78-1", "uniprot_ac": "A0A4X1SR78", "uniprot_id": "A0A4X1SR78_PIG", "mass": { "chemical_mass": 50093.0, "monoisotopic_mass": 50093.0 }, "refseq": { "ac": "XP_001927960", "name": "TERF1-interacting nuclear factor 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927960" }, "gene_names": [ { "name": "TINF2", "type": "recommended", "evidence": [ { "id": "A0A4X1SR78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ] }, { "name": "TINF2", "type": "synonym", "evidence": [ { "id": "XP_001927960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927960" } ] } ], "protein_names": [ { "name": "TERF1 interacting nuclear factor 2", "type": "synonym", "evidence": [ { "id": "A0A4X1SR78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78/entry#names_and_taxonomy" } ] }, { "name": "TERF1-interacting nuclear factor 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001927960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927960" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TINF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78", "locus": { "chromosome": "7", "start_pos": 75063979, "end_pos": 75056798, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001994", "url": "https://www.ensembl.org/id/ENSSSCG00000001994" } ] } } ], "crossref": [ { "id": "A0A4X1SR78", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SR78", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001994", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001994", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11657", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11657", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11741", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11741", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155296", "url": "https://www.ncbi.nlm.nih.gov/gene/100155296", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155296", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155296", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KERPMVM", "url": "https://omabrowser.org/oma/group/KERPMVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SR78", "url": "https://www.orthodb.org/?gene=A0A4X1SR78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15512", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15512", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15512:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15512:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-110330", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110330", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-110331", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110331", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-171306", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-171306", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-171319", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-171319", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174411", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174414", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174414", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174417", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174417", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174437", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174437", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2559586", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559586", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9670095", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9670095", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001927960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927960", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B3E9", "url": "https://www.uniprot.org/uniprotkb/A0A287B3E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B3E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B3E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SQC6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SQC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SR29", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SR29-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SR78-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SR83", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SR83-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPPEAGPAALRFAAAASWQVVRGRRVEHFPRVLEFLRSLRAAAPGLVRYRHHERLCMGLKAKLVVELILQGRPWAQVLNALNHHFPESGPVVRDPKATKQDLRKISEAQETFCQQVKQLAKDSVDLASNLQGLEQEYGETFLAAMEKLFFEYLCQLEKALPTLQAQQLQDVLNWMQPGASVTSFVLSQYVVDMGWPPPECSATDSATTSEPMGQSPPQQPRPALDNPLPKAQPGPHLPQGPISRKHPEPLAGHHFNLAPLGRRRIQSRWASTSGGHKERPTVMLFPFRNLGSPTQVISKPENREEHGTHMADPAGAVGTRAASAGKSRSPSKTLGGRALKENPIDLSASEQKENCLDCPMGPLRLSLSPPRARKPACPPSLCSSDITIGDLVLDSEEEEEENGPREGKESLENYQKTKFDTLIPTFCEYLPPSDPSAESVPFPDHIDSSRLLR", "length": 455, "header": "tr|A0A4X1SR78-1|A0A4X1SR78_PIG Isoform 1 of TERF1 interacting nuclear factor 2 OS=Sus scrofa OX=9823 GN=TINF2 PE=4 SV=1 CANONICAL=A0A4X1SR78-1" }, "isoforms": [ { "isoform_ac": "A0A287B3E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78/entry#A0A287B3E9-1", "sequence": { "sequence": "MAAPPEAGPAALRFAAAASWQVVRGRRVEHFPRVLEFLRSLRAAAPGLVRYRHHERLCMGLKAKLVVELILQGRPWAQVLNALNHHFPESGPVVRDPKATKQDLRKISEAQETFCQQVKQLAKDSVDLASNLQGLEQEYGETFLAAMEKLFFEYLCQLEKALPTLQAQQLQDVLNWMQPGASVTSFVLSQYVVDMGWPPPECSATDSATTSEPMGQSPPQQPRPALDNPLPKAQPGPHLPQGPISRKHPEPLAGHHFNLAPLGRRRIQSRWASTSGGHKERPTVMLFPFRNLGSPTQVISKPENREEHGTHMADPAGAVGTRAASAGKSRSPSKTLGGRALKENPIDLSASEQKE", "length": 355, "header": "tr|A0A287B3E9-1|A0A287B3E9_PIG Computationally mapped isoform of TERF1 interacting nuclear factor 2 OS=Sus scrofa OX=9823 GN=TINF2 PE=4 SV=2 CANONICAL=A0A4X1SR78-1" }, "locus": { "chromosome": "7", "start_pos": 75058993, "end_pos": 75057144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058537.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058537.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050643.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050643.2" } ] } }, { "isoform_ac": "A0A4X1SQC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78/entry#A0A4X1SQC6-1", "sequence": { "sequence": "MAAPPEAGPAALRFAAAASWQVVRGRRVEHFPRVLEFLRSLRAAAPGLVRYRHHERLCMGLKAKSALLLTQR", "length": 72, "header": "tr|A0A4X1SQC6-1|A0A4X1SQC6_PIG Computationally mapped isoform of TERF1 interacting nuclear factor 2 OS=Sus scrofa OX=9823 GN=TINF2 PE=4 SV=1 CANONICAL=A0A4X1SR78-1" }, "locus": { "chromosome": "7", "start_pos": 75058553, "end_pos": 75057144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086897.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086897.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063094.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063094.1" } ] } }, { "isoform_ac": "A0A4X1SR29-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78/entry#A0A4X1SR29-1", "sequence": { "sequence": "MAAPPEAGPAALRFAAAASWQVVRGRRVEHFPRVLEFLRSLRAAAPGLVRYRHHERLCMGLKAKLVVELILQGRPWAQVLNALNHHFPESGPVVRDPKATKQDLRKISEAQETFCQQVKQLAKDSVDLASNLQSALLLTQR", "length": 141, "header": "tr|A0A4X1SR29-1|A0A4X1SR29_PIG Computationally mapped isoform of TERF1 interacting nuclear factor 2 OS=Sus scrofa OX=9823 GN=TINF2 PE=4 SV=1 CANONICAL=A0A4X1SR78-1" }, "locus": { "chromosome": "7", "start_pos": 75058553, "end_pos": 75057144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076804.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076804.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066178.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066178.1" } ] } }, { "isoform_ac": "A0A4X1SR78-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78/entry#A0A4X1SR78-1", "sequence": { "sequence": "MAAPPEAGPAALRFAAAASWQVVRGRRVEHFPRVLEFLRSLRAAAPGLVRYRHHERLCMGLKAKLVVELILQGRPWAQVLNALNHHFPESGPVVRDPKATKQDLRKISEAQETFCQQVKQLAKDSVDLASNLQGLEQEYGETFLAAMEKLFFEYLCQLEKALPTLQAQQLQDVLNWMQPGASVTSFVLSQYVVDMGWPPPECSATDSATTSEPMGQSPPQQPRPALDNPLPKAQPGPHLPQGPISRKHPEPLAGHHFNLAPLGRRRIQSRWASTSGGHKERPTVMLFPFRNLGSPTQVISKPENREEHGTHMADPAGAVGTRAASAGKSRSPSKTLGGRALKENPIDLSASEQKENCLDCPMGPLRLSLSPPRARKPACPPSLCSSDITIGDLVLDSEEEEEENGPREGKESLENYQKTKFDTLIPTFCEYLPPSDPSAESVPFPDHIDSSRLLR", "length": 455, "header": "tr|A0A4X1SR78-1|A0A4X1SR78_PIG Isoform 1 of TERF1 interacting nuclear factor 2 OS=Sus scrofa OX=9823 GN=TINF2 PE=4 SV=1 CANONICAL=A0A4X1SR78-1" }, "locus": { "chromosome": "7", "start_pos": 75059624, "end_pos": 75057144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002232.4", "url": "https://www.ensembl.org/id/ENSSSCT00000002232.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002180.2", "url": "https://www.ensembl.org/id/ENSSSCP00000002180.2" } ] } }, { "isoform_ac": "A0A4X1SR83-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78/entry#A0A4X1SR83-1", "sequence": { "sequence": "MAAPPEAGPAALRFAAAASWQVVRGRRVEHFPRVLEFLRSLRAAAPGLVRYRHHERLCMGLKAKTKQDLRKISEAQETFCQQVKQLAKDSVDLASNLQGLEQEYGETFLAAMEKLFFEYLCQLEKALPTLQAQQLQDVLNWMQPGASVTSFVLSQYVVDMGWPPPECSATDSATTSEPMGQSPPQQPRPALDNPLPKAQPGPHLPQGPISRKHPEPLAGHHFNLAPLGRRRIQSRWASTSGGHKERPTVMLFPFRNLGSPTQVISKPENREEHGTHMADPAGAVGTRAASAGKSRSPSKTLGGRALKENPIDLSASEQKENCLDCPMGPLRLSLSPPRARKPACPPSLCSSDITIGDLVLDSEEEEEENGPREGKESLENYQKTKFDTLIPTFCEYLPPSDPSAESVPFPDHIDSSRLLR", "length": 420, "header": "tr|A0A4X1SR83-1|A0A4X1SR83_PIG Computationally mapped isoform of TERF1 interacting nuclear factor 2 OS=Sus scrofa OX=9823 GN=TINF2 PE=4 SV=1 CANONICAL=A0A4X1SR78-1" }, "locus": { "chromosome": "7", "start_pos": 75059624, "end_pos": 75057144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084723.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084723.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068017.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068017.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155296", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155296", "resource": "KEGG Pathway" }, { "id": "R-SSC-110330", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110330", "resource": "Reactome", "description": "Recognition and association of DNA glycosylase with site containing an affected purine" }, { "id": "R-SSC-110331", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110331", "resource": "Reactome", "description": "Cleavage of the damaged purine" }, { "id": "R-SSC-171306", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-171306", "resource": "Reactome", "description": "Packaging Of Telomere Ends" }, { "id": "R-SSC-171319", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-171319", "resource": "Reactome", "description": "Telomere Extension By Telomerase" }, { "id": "R-SSC-174411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174411", "resource": "Reactome", "description": "Polymerase switching on the C-strand of the telomere" }, { "id": "R-SSC-174414", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174414", "resource": "Reactome", "description": "Processive synthesis on the C-strand of the telomere" }, { "id": "R-SSC-174417", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174417", "resource": "Reactome", "description": "Telomere C-strand (Lagging Strand) Synthesis" }, { "id": "R-SSC-174430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174430", "resource": "Reactome", "description": "Telomere C-strand synthesis initiation" }, { "id": "R-SSC-174437", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174437", "resource": "Reactome", "description": "Removal of the Flap Intermediate from the C-strand" }, { "id": "R-SSC-2559586", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559586", "resource": "Reactome", "description": "DNA Damage/Telomere Stress Induced Senescence" }, { "id": "R-SSC-9670095", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9670095", "resource": "Reactome", "description": "Inhibition of DNA recombination at telomere" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPLVAGPAALRFAAAASWQVVRGRCVEHFPRVLEFLRSLRAVAPGLVRYRHHERLCMGLKAKVVVELILQGRPWAQVLKALNHHFPESGPIVRDPKATKQDLRKILEAQETFYQQVKQLSEAPVDLASKLQELEQEYGEPFLAAMEKLLFEYLCQLEKALPTPQAQQLQDVLSWMQPGVSITSSLAWRQYGVDMGWLLPECSVTDSVNLAEPMEQNPPQQQRLALHNPLPKAKPGTHLPQGPSSRTHPEPLAGRHFNLAPLGRRRVQSQWASTRGGHKERPTVMLFPFRNLGSPTQVISKPESKEEHAIYTADLAMGTRAASTGKSKSPCQTLGGRALKENPVDLPATEQKENCLDCYMDPLRLSLLPPRARKPVCPPSLCSSVITIGDLVLDSDEEENGQGEGKESLENYQKTKFDTLIPTLCEYLPPSGHGAIPVSSCDCRDSSRPL", "length": 451 }, "evidence": [ { "id": "A0A4X1SR78", "url": "https://omabrowser.org/oma/group/A0A4X1SR78/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "telomere capping", "id": "GO:0016233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016233", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ], "pmid": "" }, { "name": "regulation of telomere maintenance via telomere lengthening", "id": "GO:1904356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904356", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ], "pmid": "" }, { "name": "negative regulation of epithelial cell proliferation", "id": "GO:0050680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050680", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ], "pmid": "" }, { "name": "telomere assembly", "id": "GO:0032202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032202", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ], "pmid": "" }, { "name": "negative regulation of telomere maintenance via telomerase", "id": "GO:0032211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032211", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ], "pmid": "" }, { "name": "protein localization to chromosome, telomeric region", "id": "GO:0070198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070198", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "shelterin complex", "id": "GO:0070187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070187", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ], "pmid": "" }, { "name": "perinucleolar chromocenter", "id": "GO:0010370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010370", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SR78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SR78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SR78" }, { "id": "PF14973", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14973" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TERF1-interacting nuclear factor 2 N-terminal", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 169, "start_aa": "Trp", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TB30-1", "uniprot_ac": "A0A4X1TB30", "uniprot_id": "A0A4X1TB30_PIG", "mass": { "chemical_mass": 21671.0, "monoisotopic_mass": 21671.0 }, "refseq": { "ac": "XP_005665946", "name": "protein CutA isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665946" }, "gene_names": [ { "name": "CUTA", "type": "recommended", "evidence": [ { "id": "A0A4X1TB30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30" } ] }, { "name": "CUTA", "type": "synonym", "evidence": [ { "id": "XP_005665946", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665946" } ] } ], "protein_names": [ { "name": "Protein CutA", "type": "recommended", "evidence": [ { "id": "A0A4X1TB30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30/entry#names_and_taxonomy" } ] }, { "name": "Brain acetylcholinesterase putative membrane anchor", "type": "synonym", "evidence": [ { "id": "A0A4X1TB30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30/entry#names_and_taxonomy" } ] }, { "name": "protein CutA isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005665946", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665946" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB30", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CUTA", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30", "locus": { "chromosome": "7", "start_pos": 29720094, "end_pos": 29721769, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001512", "url": "https://www.ensembl.org/id/ENSSSCG00000001512" } ] } } ], "crossref": [ { "id": "A0A4X1TB30", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TB30", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001512", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001512", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152220", "url": "https://www.ncbi.nlm.nih.gov/gene/100152220", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TB30", "url": "https://www.orthodb.org/?gene=A0A4X1TB30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23419:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23419:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005665946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665946", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BCM2", "url": "https://www.uniprot.org/uniprotkb/A0A287BCM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BCM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BCM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T7L3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T7L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TB30", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TB30-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGWLGLSRGVRCFLITWLSPSIGCMRGVRAPAILLGGGATLLLSLLWMPALLPIVSRLLLLPRALLSMASGSPPTQPTPASGSAYVPGSVSAAFVTCPNEKVAKEIARAVVEKRLAACVNLIPQITSIYEWKGKIEEDSEVLMMIKTQSSLVPALTDFVRSVHPYEVAEVIALPVEQGNSPYLHWVRQVTESVPDSGTVLP", "length": 202, "header": "tr|A0A4X1TB30-1|A0A4X1TB30_PIG Isoform 1 of Protein CutA OS=Sus scrofa OX=9823 GN=CUTA PE=1 SV=1 CANONICAL=A0A4X1TB30-1" }, "isoforms": [ { "isoform_ac": "A0A287BCM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30/entry#A0A287BCM2-1", "sequence": { "sequence": "MQAVDSFLGCLSGDTEFTSCSQATLLLSLLWMPALLPIVSRLLLLPRALLSMASGSPPTQPTPASGSAYVPGSVSAAFVTCPNEKVAKEIARAVVEKRLAACVNLIPQITSIYEWKGKIEEDSEVLMMIKTQSSLVPALTDFVRSVHPYEVAEVIALPVEQGNSPYLHWVRQVTESVPDSGTVLP", "length": 185, "header": "tr|A0A287BCM2-1|A0A287BCM2_PIG Computationally mapped isoform of Protein CutA OS=Sus scrofa OX=9823 GN=CUTA PE=1 SV=1 CANONICAL=A0A4X1TB30-1" }, "locus": { "chromosome": "7", "start_pos": 29721248, "end_pos": 29720186, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041325.2", "url": "https://www.ensembl.org/id/ENSSSCT00000041325.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054270.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054270.1" } ] } }, { "isoform_ac": "A0A4X1T7L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30/entry#A0A4X1T7L3-1", "sequence": { "sequence": "MRGVRAPAILLGGGATLLLSLLWMPALLPIVSRLLLLPRALLSMASGSPPTQPTPASGSAYVPGSVSAAFVTCPNEKVAKEIARAVVEKRLAACVNLIPQITSIYEWKGKIEEDSEVLMLCTPLRSGRGDCTASGAGELPIPALGAPGYRISA", "length": 153, "header": "tr|A0A4X1T7L3-1|A0A4X1T7L3_PIG Computationally mapped isoform of CutA divalent cation tolerance homolog OS=Sus scrofa OX=9823 GN=CUTA PE=1 SV=1 CANONICAL=A0A4X1TB30-1" }, "locus": { "chromosome": "7", "start_pos": 29721478, "end_pos": 29720208, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042331.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042331.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041826.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041826.2" } ] } }, { "isoform_ac": "A0A4X1TB30-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30/entry#A0A4X1TB30-1", "sequence": { "sequence": "MLGWLGLSRGVRCFLITWLSPSIGCMRGVRAPAILLGGGATLLLSLLWMPALLPIVSRLLLLPRALLSMASGSPPTQPTPASGSAYVPGSVSAAFVTCPNEKVAKEIARAVVEKRLAACVNLIPQITSIYEWKGKIEEDSEVLMMIKTQSSLVPALTDFVRSVHPYEVAEVIALPVEQGNSPYLHWVRQVTESVPDSGTVLP", "length": 202, "header": "tr|A0A4X1TB30-1|A0A4X1TB30_PIG Isoform 1 of Protein CutA OS=Sus scrofa OX=9823 GN=CUTA PE=1 SV=1 CANONICAL=A0A4X1TB30-1" }, "locus": { "chromosome": "7", "start_pos": 29721636, "end_pos": 29720186, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001685.4", "url": "https://www.ensembl.org/id/ENSSSCT00000001685.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001641.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001641.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB30", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB30", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30" } ], "pmid": "" }, { "name": "response to metal ion", "id": "GO:0010038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010038", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB30", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB30", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB30", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB30", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30" } ], "pmid": "" }, { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB30", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB30" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 79 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SJZ4-1", "uniprot_ac": "A0A4X1SJZ4", "uniprot_id": "A0A4X1SJZ4_PIG", "mass": { "chemical_mass": 25359.0, "monoisotopic_mass": 25359.0 }, "refseq": { "ac": "XP_005663581", "name": "DNA-directed RNA polymerase III subunit RPC7-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663581" }, "gene_names": [ { "name": "POLR3GL", "type": "recommended", "evidence": [ { "id": "A0A4X1SJZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJZ4" } ] }, { "name": "POLR3GL", "type": "synonym", "evidence": [ { "id": "XP_005663581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663581" } ] } ], "protein_names": [ { "name": "DNA-directed RNA polymerase III subunit", "type": "recommended", "evidence": [ { "id": "A0A4X1SJZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJZ4/entry#names_and_taxonomy" } ] }, { "name": "DNA-directed RNA polymerase III subunit RPC7-like", "type": "synonym", "evidence": [ { "id": "XP_005663581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663581" } ] } ], "function": [ { "annotation": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ06", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ06#function" }, { "database": "UniProtKB", "id": "PIRNR000777", "url": "https://www.uniprot.org/uniprotkb/PIRNR000777#function" }, { "database": "UniProtKB", "id": "A0A4X1SJZ4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJZ4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJZ4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJZ4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "POLR3GL", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJZ4", "locus": {} } ], "crossref": [ { "id": "A0A4X1SJZ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SJZ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100152157", "url": "https://www.ncbi.nlm.nih.gov/gene/100152157", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152157", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152157", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KDLHAPF", "url": "https://omabrowser.org/oma/group/KDLHAPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SJZ4", "url": "https://www.orthodb.org/?gene=A0A4X1SJZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15367", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15367", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15367:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15367:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-76061", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76061", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-76066", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-76071", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76071", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005663581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663581", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SJ06", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SJ06-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SJZ4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SJZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRSGGRGRGRGQLTFNMEAVGIGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPVDSAIDWNPDWRRLPRELKIRVRKIQKERTTILLPKRPLKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY", "length": 218, "header": "tr|A0A4X1SJZ4-1|A0A4X1SJZ4_PIG Isoform 1 of DNA-directed RNA polymerase III subunit OS=Sus scrofa OX=9823 GN=POLR3GL PE=3 SV=1 CANONICAL=A0A4X1SJZ4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SJ06-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJZ4/entry#A0A4X1SJ06-1", "sequence": { "sequence": "MASRSGGRGRGRGQLTFNMEAVGIGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDWRRLPRELKIRVRKIQKERTTILLPKRPLKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY", "length": 195, "header": "tr|A0A4X1SJ06-1|A0A4X1SJZ4_PIG Computationally mapped isoform of DNA-directed RNA polymerase III subunit OS=Sus scrofa OX=9823 GN=POLR3GL PE=3 SV=1 CANONICAL=A0A4X1SJZ4-1" }, "locus": { "chromosome": "4", "start_pos": 99367809, "end_pos": 99364743, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080352.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080352.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072098.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072098.1" } ] } }, { "isoform_ac": "A0A4X1SJZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJZ4/entry#A0A4X1SJZ4-1", "sequence": { "sequence": "MASRSGGRGRGRGQLTFNMEAVGIGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPVDSAIDWNPDWRRLPRELKIRVRKIQKERTTILLPKRPLKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY", "length": 218, "header": "tr|A0A4X1SJZ4-1|A0A4X1SJZ4_PIG Isoform 1 of DNA-directed RNA polymerase III subunit OS=Sus scrofa OX=9823 GN=POLR3GL PE=3 SV=1 CANONICAL=A0A4X1SJZ4-1" }, "locus": { "chromosome": "4", "start_pos": 99367809, "end_pos": 99364743, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007320.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007320.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007125.2", "url": "https://www.ensembl.org/id/ENSSSCP00000007125.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ06", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ06" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152157", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152157", "resource": "KEGG Pathway" }, { "id": "R-SSC-76061", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76061", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 1 Promoter" }, { "id": "R-SSC-76066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76066", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 2 Promoter" }, { "id": "R-SSC-76071", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76071", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 3 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N1N3-1", "protein_name": "DNA-directed RNA polymerase III subunit", "gene_name": "Polr3gl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASRGGGRGRGRGQLTFNMEAVGIGKGDALPPPTLQPSPLFPPLEFHPVPLPAGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPMDNAIDWNPDWRRLPRELKIRVRKLQKERATILLPKRPPKAMEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEDKEEGEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY", "length": 218 }, "evidence": [ { "id": "A0A4X1SJZ4", "url": "https://omabrowser.org/oma/group/A0A4X1SJZ4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V1AFA5-1", "protein_name": "RNA polymerase III subunit GL", "gene_name": "POLR3GL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGQQGWGAQWGWGWWGGGDWGAQRCPHPIGPPRVLIPPPHVYPIASPTFPPPHPLLPPPIYPPRAAPPPPPFSPSAPQRPPPAPHGVPWPRSGPWGADVQHGGGGHREGRRAAAPHPAALPALPDIERYSDKYQLSSPIDGAIEWNPDWRRFPRELKIRVRRLRKGRSCAPPPRTAPRPPPPDKEETIKKLEHLEKKEEEVTSEEEEKEEEEEGEGRDEEGEEYDEEEHEEETDYIMSYFDNGEDFGADSDDNGDEAVY", "length": 259 }, "evidence": [ { "id": "A0A4X1SJZ4", "url": "https://omabrowser.org/oma/group/A0A4X1SJZ4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q1RMR0-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC7-like", "gene_name": "POLR3GL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASRGGGRGCGRGQLTFNVEAVGIGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPIDNAIDWNPDWRRLPRELKIRVRKLQKERTTIILPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY", "length": 218 }, "evidence": [ { "id": "A0A4X1SJZ4", "url": "https://omabrowser.org/oma/group/A0A4X1SJZ4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R0C0-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC7-like", "gene_name": "Polr3gl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRGGGRGRGRGQLTFNMEAVGIGKGDALPPPTLQPSPLFPPLEFHPVPLPAGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPIDNAIDWNPDWRRLPSELKIRVRKVQKERTTIILPKRPPKSTDDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEGEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY", "length": 218 }, "evidence": [ { "id": "A0A4X1SJZ4", "url": "https://omabrowser.org/oma/group/A0A4X1SJZ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BT43-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC7-like", "gene_name": "POLR3GL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRGGGRGRGRGQLTFNVEAVGIGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPIDNAIDWNPDWRRLPRELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY", "length": 218 }, "evidence": [ { "id": "A0A4X1SJZ4", "url": "https://omabrowser.org/oma/group/A0A4X1SJZ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJZ4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJZ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "RNA polymerase III complex", "id": "GO:0005666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005666", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJZ4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJZ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SJ12-1", "uniprot_ac": "A0A4X1SJ12", "uniprot_id": "A0A4X1SJ12_PIG", "mass": { "chemical_mass": 66161.0, "monoisotopic_mass": 66161.0 }, "refseq": { "ac": "NP_001231234", "name": "nucleolar protein 56", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231234" }, "gene_names": [ { "name": "NOP56", "type": "recommended", "evidence": [ { "id": "A0A4X1SJ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12" } ] }, { "name": "NOP56", "type": "synonym", "evidence": [ { "id": "NP_001231234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231234" } ] } ], "protein_names": [ { "name": "Nucleolar protein 56", "type": "recommended", "evidence": [ { "id": "A0A4X1SJ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12/entry#names_and_taxonomy" } ] }, { "name": "NOP56 ribonucleoprotein homolog", "type": "synonym", "evidence": [ { "id": "NP_001231234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231234" } ] }, { "name": "Nucleolar protein 5A", "type": "synonym", "evidence": [ { "id": "A0A4X1SJ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12/entry#names_and_taxonomy" } ] }, { "name": "nucleolar protein 56", "type": "synonym", "evidence": [ { "id": "NP_001231234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231234" } ] } ], "function": [ { "annotation": "Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) complexes that function in methylation of multiple sites on ribosomal RNAs (rRNAs) and messenger RNAs (mRNAs).", "evidence": [ { "database": "UniProtKB", "id": "I3LB64", "url": "https://www.uniprot.org/uniprotkb/I3LB64#function" }, { "database": "UniProtKB", "id": "ARBA00053627", "url": "https://www.uniprot.org/uniprotkb/ARBA00053627#function" }, { "database": "UniProtKB", "id": "A0A4X1SJ12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NOP56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12", "locus": { "chromosome": "17", "start_pos": 32960102, "end_pos": 32965370, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027676", "url": "https://www.ensembl.org/id/ENSSSCG00000027676" } ] } } ], "crossref": [ { "id": "A0A4X1SJ12", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SJ12", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000027676", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027676", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100512446", "url": "https://www.ncbi.nlm.nih.gov/gene/100512446", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512446", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512446", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SJ12", "url": "https://www.orthodb.org/?gene=A0A4X1SJ12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10894", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10894", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10894:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10894:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08156", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08156", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001231234", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231234", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SJ12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SJ12-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LB64", "url": "https://www.uniprot.org/uniprotkb/I3LB64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LB64-1", "url": "https://www.uniprot.org/uniprotkb/I3LB64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLLHVLFEHAVGYALLALKEVEEISLLLPQVEECVLNLGKFHNIVRLVAFSPFSSSQVALENANAVSEGVVHEDLRLFLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEVLRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEEKLEKLEELTMDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLEVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAAVALASSENSSSTPEECEETSERPKKKKKKQKPQEVPQENGMEDPPVSFSKPKKKKAFSKEELVSSDLEERAGSGSLPKRKKSLSSPVSDPEESGNKKIPKKKRKLSPKEEPLSSGPEEAAVSKSSGSKKKKKLQKLSQET", "length": 596, "header": "tr|A0A4X1SJ12-1|A0A4X1SJ12_PIG Isoform 1 of Nucleolar protein 56 OS=Sus scrofa OX=9823 GN=NOP56 PE=1 SV=1 CANONICAL=A0A4X1SJ12-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SJ12-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12/entry#A0A4X1SJ12-1", "sequence": { "sequence": "MVLLHVLFEHAVGYALLALKEVEEISLLLPQVEECVLNLGKFHNIVRLVAFSPFSSSQVALENANAVSEGVVHEDLRLFLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEVLRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEEKLEKLEELTMDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLEVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAAVALASSENSSSTPEECEETSERPKKKKKKQKPQEVPQENGMEDPPVSFSKPKKKKAFSKEELVSSDLEERAGSGSLPKRKKSLSSPVSDPEESGNKKIPKKKRKLSPKEEPLSSGPEEAAVSKSSGSKKKKKLQKLSQET", "length": 596, "header": "tr|A0A4X1SJ12-1|A0A4X1SJ12_PIG Isoform 1 of Nucleolar protein 56 OS=Sus scrofa OX=9823 GN=NOP56 PE=1 SV=1 CANONICAL=A0A4X1SJ12-1" }, "locus": { "chromosome": "17", "start_pos": 32965303, "end_pos": 32960212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007848.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007848.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007637.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007637.4" } ] } }, { "isoform_ac": "I3LB64-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12/entry#I3LB64-1", "sequence": { "sequence": "VLLHVLFEHAVGYALLALKEVEEISLLLPQVEECVLNLGKFHNIVRLVAFSPFSSSQVALENANAVSEGVVHEDLRLFLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEVLRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEEKLEKLEELTMDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLEVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAAVALASSENSSSTPEECEETSERPKKKKKKQKPQEEELVSSDLEERAGSGSLPKRKKSLSSPVSDPEESGNKKIPKKKRKLSPKEEPLSSGPEEAAVSKSSGSKKKKKLQKLSQET", "length": 570, "header": "tr|I3LB64-1|A0A4X1SJ12_PIG Computationally mapped isoform of Nucleolar protein 56 OS=Sus scrofa OX=9823 GN=NOP56 PE=1 SV=3 CANONICAL=A0A4X1SJ12-1" }, "locus": { "chromosome": "17", "start_pos": 32965145, "end_pos": 32960212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029302.4", "url": "https://www.ensembl.org/id/ENSSSCT00000029302.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021283.3", "url": "https://www.ensembl.org/id/ENSSSCP00000021283.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LB64", "url": "https://www.uniprot.org/uniprotkb/I3LB64" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512446", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512446", "resource": "KEGG Pathway" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12" } ], "pmid": "" }, { "name": "pre-snoRNP complex", "id": "GO:0070761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070761", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12" } ], "pmid": "" }, { "name": "box C/D methylation guide snoRNP complex", "id": "GO:0031428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031428", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12" } ], "pmid": "" }, { "name": "histone methyltransferase binding", "id": "GO:1990226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990226", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12" } ], "pmid": "" }, { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SJ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ12" }, { "id": "PS51358", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51358" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nop", "eco_id": "ECO_0000259", "start_pos": 292, "end_pos": 410, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 207, "end_pos": 209 }, { "start_pos": 464, "end_pos": 466 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SJ31-1", "uniprot_ac": "A0A4X1SJ31", "uniprot_id": "A0A4X1SJ31_PIG", "mass": { "chemical_mass": 13995.0, "monoisotopic_mass": 13995.0 }, "refseq": {}, "gene_names": [ { "name": "H2AC21", "type": "recommended", "evidence": [ { "id": "A0A4X1SJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31" } ] } ], "protein_names": [ { "name": "Histone H2A", "type": "recommended", "evidence": [ { "id": "A0A4X1SJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ31", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "H2AC21", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31", "locus": { "chromosome": "4", "start_pos": 99168647, "end_pos": 99168255, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000063420", "url": "https://www.ensembl.org/id/ENSSSCG00000063420" } ] } } ], "crossref": [ { "id": "A0A4X1SJ31", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SJ31", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00074", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00074", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "THHEYAK", "url": "https://omabrowser.org/oma/group/THHEYAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SJ31", "url": "https://www.orthodb.org/?gene=A0A4X1SJ31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23430", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23430", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00125", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16211", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16211", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3214858", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214858", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5689603", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5689901", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689901", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SJ31", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SJ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTESHKPGKNK", "length": 130, "header": "tr|A0A4X1SJ31-1|A0A4X1SJ31_PIG Isoform 1 of Histone H2A OS=Sus scrofa OX=9823 GN=H2AC21 PE=1 SV=1 CANONICAL=A0A4X1SJ31-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SJ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31/entry#A0A4X1SJ31-1", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTESHKPGKNK", "length": 130, "header": "tr|A0A4X1SJ31-1|A0A4X1SJ31_PIG Isoform 1 of Histone H2A OS=Sus scrofa OX=9823 GN=H2AC21 PE=1 SV=1 CANONICAL=A0A4X1SJ31-1" }, "locus": { "chromosome": "4", "start_pos": 99168644, "end_pos": 99168255, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007306.2", "url": "https://www.ensembl.org/id/ENSSSCT00000007306.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007111.1", "url": "https://www.ensembl.org/id/ENSSSCP00000007111.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ31", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3214858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214858", "resource": "Reactome", "description": "RMTs methylate histone arginines" }, { "id": "R-SSC-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "resource": "Reactome", "description": "UCH proteinases" }, { "id": "R-SSC-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-SSC-5689901", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689901", "resource": "Reactome", "description": "Metalloprotease DUBs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1RNY8-1", "protein_name": "Histone H2A", "gene_name": "H2AX", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGRGKSGGKARAKAKSRSSRAGLQFPVGRVHRLLRRGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTGGGAASPAKAGKKGSGQQSQEY", "length": 143 }, "evidence": [ { "id": "A0A4X1SJ31", "url": "https://omabrowser.org/oma/group/A0A4X1SJ31/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7F5W3-1", "protein_name": "Histone H2A", "gene_name": "hist1h2a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKATKGK", "length": 128 }, "evidence": [ { "id": "A0A4X1SJ31", "url": "https://omabrowser.org/oma/group/A0A4X1SJ31/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F2Z4J1-1", "protein_name": "Histone H2A", "gene_name": "H2AC6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A4X1SJ31", "url": "https://omabrowser.org/oma/group/A0A4X1SJ31/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P84051-1", "protein_name": "Histone H2A", "gene_name": "His2A:CG33850", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSGRGKGGKVKGKAKSRSNRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKKA", "length": 124 }, "evidence": [ { "id": "A0A4X1SJ31", "url": "https://omabrowser.org/oma/group/A0A4X1SJ31/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q6FI13-1", "protein_name": "Histone H2A type 2-A", "gene_name": "H2AC19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A4X1SJ31", "url": "https://omabrowser.org/oma/group/A0A4X1SJ31/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ31", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ31", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ31", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ31", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ31", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ31", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJ31", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31" }, { "id": "PF00125", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Core Histone H2A/H2B/H3", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 89, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJ31" }, { "id": "PF16211", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histone H2A C-terminal", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 125, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SJK3-1", "uniprot_ac": "A0A4X1SJK3", "uniprot_id": "A0A4X1SJK3_PIG", "mass": { "chemical_mass": 10350.0, "monoisotopic_mass": 10350.0 }, "refseq": { "ac": "XP_003131683", "name": "dynein light chain 2, cytoplasmic", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131683" }, "gene_names": [ { "name": "DYNLL2", "type": "recommended", "evidence": [ { "id": "A0A4X1SJK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3" } ] }, { "name": "DYNLL2", "type": "synonym", "evidence": [ { "id": "XP_003131683", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131683" } ] } ], "protein_names": [ { "name": "Dynein light chain", "type": "recommended", "evidence": [ { "id": "A0A4X1SJK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3/entry#names_and_taxonomy" } ] }, { "name": "dynein light chain 2, cytoplasmic", "type": "synonym", "evidence": [ { "id": "XP_003131683", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131683" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DYNLL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3", "locus": { "chromosome": "12", "start_pos": 34356472, "end_pos": 34349294, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000020962", "url": "https://www.ensembl.org/id/ENSSSCG00000020962" } ] } } ], "crossref": [ { "id": "A0A4X1SJK3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SJK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000020962", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000020962", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21452", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21452", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512860", "url": "https://www.ncbi.nlm.nih.gov/gene/100512860", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512860", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512860", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THEKGHF", "url": "https://omabrowser.org/oma/group/THEKGHF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SJK3", "url": "https://www.orthodb.org/?gene=A0A4X1SJK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11886", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11886", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11886:SF113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11886:SF113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-139910", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-139910", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2132295", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3371497", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371497", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68877", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9646399", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9646399", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131683", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131683", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SJK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SJK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8I6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "length": 89, "header": "tr|A0A4X1SJK3-1|A0A4X1SJK3_PIG Isoform 1 of Dynein light chain OS=Sus scrofa OX=9823 GN=DYNLL2 PE=1 SV=1 CANONICAL=A0A4X1SJK3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SJK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3/entry#A0A4X1SJK3-1", "sequence": { "sequence": "MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "length": 89, "header": "tr|A0A4X1SJK3-1|A0A4X1SJK3_PIG Isoform 1 of Dynein light chain OS=Sus scrofa OX=9823 GN=DYNLL2 PE=1 SV=1 CANONICAL=A0A4X1SJK3-1" }, "locus": { "chromosome": "12", "start_pos": 34354523, "end_pos": 34352345, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027876.2", "url": "https://www.ensembl.org/id/ENSSSCT00000027876.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020319.1", "url": "https://www.ensembl.org/id/ENSSSCP00000020319.1" } ] } }, { "isoform_ac": "A0A5G2R8I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3/entry#A0A5G2R8I6-1", "sequence": { "sequence": "MSVFSAALTFCVCLPQGGPTPICYSSCPEYGVATSSLCFFCSVTMSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "length": 133, "header": "tr|A0A5G2R8I6-1|A0A4X1SJK3_PIG Computationally mapped isoform of Dynein light chain OS=Sus scrofa OX=9823 GN=DYNLL2 PE=1 SV=1 CANONICAL=A0A4X1SJK3-1" }, "locus": { "chromosome": "12", "start_pos": 34354523, "end_pos": 34352213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088839.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088839.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070437.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070437.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8I6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8I6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512860", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512860", "resource": "KEGG Pathway" }, { "id": "R-SSC-139910", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-139910", "resource": "Reactome", "description": "Activation of BMF and translocation to mitochondria" }, { "id": "R-SSC-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-SSC-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-SSC-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1632852", "resource": "Reactome", "description": "Macroautophagy" }, { "id": "R-SSC-2132295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "resource": "Reactome", "description": "MHC class II antigen presentation" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-SSC-3371497", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371497", "resource": "Reactome", "description": "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" }, { "id": "R-SSC-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620924", "resource": "Reactome", "description": "Intraflagellar transport" }, { "id": "R-SSC-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-SSC-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-SSC-68877", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "resource": "Reactome", "description": "Mitotic Prometaphase" }, { "id": "R-SSC-9646399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9646399", "resource": "Reactome", "description": "Aggrephagy" }, { "id": "R-SSC-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "G3H1E5-1", "protein_name": "Dynein light chain", "gene_name": "Dynll2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "length": 89 }, "evidence": [ { "id": "A0A4X1SJK3", "url": "https://omabrowser.org/oma/group/A0A4X1SJK3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O96860-1", "protein_name": "Dynein light chain 2, cytoplasmic", "gene_name": "Cdlc2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDRKAVIKNADMSEEMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYLGQVAILLFKSG", "length": 89 }, "evidence": [ { "id": "A0A4X1SJK3", "url": "https://omabrowser.org/oma/group/A0A4X1SJK3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q02647-1", "protein_name": "Dynein light chain 1, cytoplasmic", "gene_name": "DYN2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDENKSTPIVKASDITDKLKEDILTISKDALDKYQLERDIAGTVKKQLDVKYGNTWHVIVGKNFGSYVTHEKGHFVYFYIGPLAFLVFKTA", "length": 92 }, "evidence": [ { "id": "A0A4X1SJK3", "url": "https://omabrowser.org/oma/group/A0A4X1SJK3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3MHR3-1", "protein_name": "Dynein light chain 2, cytoplasmic", "gene_name": "DYNLL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "length": 89 }, "evidence": [ { "id": "A0A4X1SJK3", "url": "https://omabrowser.org/oma/group/A0A4X1SJK3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q78P75-1", "protein_name": "Dynein light chain 2, cytoplasmic", "gene_name": "Dynll2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "length": 89 }, "evidence": [ { "id": "A0A4X1SJK3", "url": "https://omabrowser.org/oma/group/A0A4X1SJK3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96FJ2-1", "protein_name": "Dynein light chain 2, cytoplasmic", "gene_name": "DYNLL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "length": 89 }, "evidence": [ { "id": "A0A4X1SJK3", "url": "https://omabrowser.org/oma/group/A0A4X1SJK3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D0M5-1", "protein_name": "Dynein light chain 2, cytoplasmic", "gene_name": "Dynll2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "length": 89 }, "evidence": [ { "id": "A0A4X1SJK3", "url": "https://omabrowser.org/oma/group/A0A4X1SJK3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3" } ], "pmid": "" }, { "name": "myosin V complex", "id": "GO:0031475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031475", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3" } ], "pmid": "" }, { "name": "9+0 non-motile cilium", "id": "GO:0097731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097731", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule-based process", "id": "GO:0007017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007017", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SJK8-1", "uniprot_ac": "A0A4X1SJK8", "uniprot_id": "A0A4X1SJK8_PIG", "mass": { "chemical_mass": 15325.0, "monoisotopic_mass": 15325.0 }, "refseq": { "ac": "XP_003359295", "name": "40S ribosomal protein S24 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003359295" }, "gene_names": [ { "name": "RPS24", "type": "recommended", "evidence": [ { "id": "A0A4X1SJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ] }, { "name": "RPS24", "type": "synonym", "evidence": [ { "id": "XP_003359295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003359295" } ] } ], "protein_names": [ { "name": "40S ribosomal protein S24", "type": "recommended", "evidence": [ { "id": "A0A4X1SJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S24 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003359295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003359295" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPS24", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8", "locus": {} } ], "crossref": [ { "id": "A0A4X1SJK8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SJK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000039544", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000039544", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100155012", "url": "https://www.ncbi.nlm.nih.gov/gene/100155012", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "3J7R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=3J7R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155012", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155012", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SJK8", "url": "https://www.orthodb.org/?gene=A0A4X1SJK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8W4FAW3", "url": "https://www.orthodb.org/?gene=A0A8W4FAW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "I3LJP6", "url": "https://www.orthodb.org/?gene=I3LJP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10496", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10496", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00003j7r", "url": "https://www.rcsb.org/structure/pdb_00003j7r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "3J7R", "url": "https://www.rcsb.org/structure/3J7R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF01282", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01282", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003359295", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003359295", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SJK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SK93", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SK93-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LJP6", "url": "https://www.uniprot.org/uniprotkb/I3LJP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LJP6-1", "url": "https://www.uniprot.org/uniprotkb/I3LJP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNDTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKVRGTAKANVGAGKKKK", "length": 132, "header": "tr|A0A4X1SJK8-1|A0A4X1SJK8_PIG Isoform 1 of 40S ribosomal protein S24 OS=Sus scrofa OX=9823 GN=RPS24 PE=1 SV=1 CANONICAL=A0A4X1SJK8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SJK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8/entry#A0A4X1SJK8-1", "sequence": { "sequence": "MNDTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKVRGTAKANVGAGKKKK", "length": 132, "header": "tr|A0A4X1SJK8-1|A0A4X1SJK8_PIG Isoform 1 of 40S ribosomal protein S24 OS=Sus scrofa OX=9823 GN=RPS24 PE=1 SV=1 CANONICAL=A0A4X1SJK8-1" }, "locus": { "chromosome": "14", "start_pos": 80478368, "end_pos": 80473973, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066963.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066963.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064538.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064538.2" } ] } }, { "isoform_ac": "A0A4X1SK93-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8/entry#A0A4X1SK93-1", "sequence": { "sequence": "MTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKVRGTAKANVGAGKKKVTCSEKPRNVVS", "length": 131, "header": "tr|A0A4X1SK93-1|A0A4X1SK93_PIG Computationally mapped isoform of 40S ribosomal protein S24 OS=Sus scrofa OX=9823 GN=RPS24 PE=3 SV=1 CANONICAL=A0A4X1SJK8-1" }, "locus": { "chromosome": "14", "start_pos": 80477899, "end_pos": 80475873, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057256.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057256.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052290.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052290.2" } ] } }, { "isoform_ac": "A0A8W4FAW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8/entry#A0A8W4FAW3-1", "sequence": { "sequence": "MNDTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKVRGTAKANVGAGKKKE", "length": 132, "header": "tr|A0A8W4FAW3-1|A0A4X1SJK8_PIG Computationally mapped isoform of 40S ribosomal protein S24 OS=Sus scrofa OX=9823 GN=RPS24 PE=1 SV=1 CANONICAL=A0A4X1SJK8-1" }, "locus": { "chromosome": "14", "start_pos": 80480735, "end_pos": 80473973, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104893.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104893.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075986.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075986.1" } ] } }, { "isoform_ac": "I3LJP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8/entry#I3LJP6-1", "sequence": { "sequence": "MNDTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKVRGTAKANVGAGKKK", "length": 131, "header": "tr|I3LJP6-1|A0A4X1SJK8_PIG Computationally mapped isoform of 40S ribosomal protein S24 OS=Sus scrofa OX=9823 GN=RPS24 PE=1 SV=4 CANONICAL=A0A4X1SJK8-1" }, "locus": { "chromosome": "14", "start_pos": 80478368, "end_pos": 80473973, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096351.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096351.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081168.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081168.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Structure of the mammalian ribosome-Sec61 complex to 3.4 A resolution.", "journal": "Cell", "date": "2014", "authors": "Voorhees Rebecca M, Fern\u00e1ndez Israel S, Scheres Sjors H W, Hegde Ramanujan S", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ], "reference": [ { "type": "PubMed", "id": "24930395", "url": "https://glygen.org/publication/PubMed/24930395" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155012", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155012", "resource": "KEGG Pathway" }, { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-SSC-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ], "pmid": "" }, { "name": "erythrocyte homeostasis", "id": "GO:0034101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034101", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 2, "end_pos": 4 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SJX5-1", "uniprot_ac": "A0A4X1SJX5", "uniprot_id": "A0A4X1SJX5_PIG", "mass": { "chemical_mass": 9725.0, "monoisotopic_mass": 9725.0 }, "refseq": { "ac": "NP_001177142", "name": "small nuclear ribonucleoprotein F", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177142" }, "gene_names": [ { "name": "SNRPF", "type": "recommended", "evidence": [ { "id": "A0A4X1SJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ] }, { "name": "SNRPF", "type": "synonym", "evidence": [ { "id": "NP_001177142", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177142" } ] } ], "protein_names": [ { "name": "Small nuclear ribonucleoprotein F", "type": "recommended", "evidence": [ { "id": "A0A4X1SJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5/entry#names_and_taxonomy" } ] }, { "name": "Sm protein F", "type": "synonym", "evidence": [ { "id": "A0A4X1SJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5/entry#names_and_taxonomy" } ] }, { "name": "small nuclear ribonucleoprotein F", "type": "synonym", "evidence": [ { "id": "NP_001177142", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177142" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SNRPF", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5", "locus": { "chromosome": "5", "start_pos": 87604596, "end_pos": 87622879, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000895", "url": "https://www.ensembl.org/id/ENSSSCG00000000895" } ] } } ], "crossref": [ { "id": "A0A4X1SJX5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SJX5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000895", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000895", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01722", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01722", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155855", "url": "https://www.ncbi.nlm.nih.gov/gene/100155855", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155855", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155855", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYMNVQL", "url": "https://omabrowser.org/oma/group/GYMNVQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SJX5", "url": "https://www.orthodb.org/?gene=A0A4X1SJX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11021", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11021", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11021:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11021:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11021:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11021:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-111367", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111367", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-191859", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-191859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73856", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73856", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-77588", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77588", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001177142", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177142", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SJX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9M0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9M0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "length": 86, "header": "tr|A0A4X1SJX5-1|A0A4X1SJX5_PIG Isoform 1 of Small nuclear ribonucleoprotein F OS=Sus scrofa OX=9823 GN=SNRPF PE=1 SV=1 CANONICAL=A0A4X1SJX5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SJX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5/entry#A0A4X1SJX5-1", "sequence": { "sequence": "MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "length": 86, "header": "tr|A0A4X1SJX5-1|A0A4X1SJX5_PIG Isoform 1 of Small nuclear ribonucleoprotein F OS=Sus scrofa OX=9823 GN=SNRPF PE=1 SV=1 CANONICAL=A0A4X1SJX5-1" }, "locus": { "chromosome": "5", "start_pos": 87622739, "end_pos": 87615223, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000979.5", "url": "https://www.ensembl.org/id/ENSSSCT00000000979.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000958.2", "url": "https://www.ensembl.org/id/ENSSSCP00000000958.2" } ] } }, { "isoform_ac": "A0A5G2R9M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5/entry#A0A5G2R9M0-1", "sequence": { "sequence": "MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQIFVYILGILYQSKILLFQLCEDLE", "length": 67, "header": "tr|A0A5G2R9M0-1|A0A4X1SJX5_PIG Computationally mapped isoform of Small nuclear ribonucleoprotein F OS=Sus scrofa OX=9823 GN=SNRPF PE=1 SV=1 CANONICAL=A0A4X1SJX5-1" }, "locus": { "chromosome": "5", "start_pos": 87622739, "end_pos": 87604599, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076923.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076923.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070824.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070824.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9M0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9M0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155855", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155855", "resource": "KEGG Pathway" }, { "id": "R-SSC-111367", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111367", "resource": "Reactome", "description": "SLBP independent Processing of Histone Pre-mRNAs" }, { "id": "R-SSC-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-191859", "resource": "Reactome", "description": "snRNP Assembly" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-SSC-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" }, { "id": "R-SSC-73856", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73856", "resource": "Reactome", "description": "RNA Polymerase II Transcription Termination" }, { "id": "R-SSC-77588", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77588", "resource": "Reactome", "description": "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" }, { "id": "R-SSC-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" }, { "id": "R-SSC-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1RSB5-1", "protein_name": "Small nuclear ribonucleoprotein F", "gene_name": "SNRPF", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "length": 86 }, "evidence": [ { "id": "A0A4X1SJX5", "url": "https://omabrowser.org/oma/group/A0A4X1SJX5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8C2MF50-1", "protein_name": "Small nuclear ribonucleoprotein F", "gene_name": "Snrpf", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "length": 86 }, "evidence": [ { "id": "A0A4X1SJX5", "url": "https://omabrowser.org/oma/group/A0A4X1SJX5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4AAT4-1", "protein_name": "Small nuclear ribonucleoprotein F", "gene_name": "Snrpf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "length": 86 }, "evidence": [ { "id": "A0A4X1SJX5", "url": "https://omabrowser.org/oma/group/A0A4X1SJX5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P54999-1", "protein_name": "Small nuclear ribonucleoprotein F", "gene_name": "SMX3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSESSDISAMQPVNPKPFLKGLVNHRVGVKLKFNSTEYRGTLVSTDNYFNLQLNEAEEFVAGVSHGTLGEIFIRCNNVLYIRELPN", "length": 86 }, "evidence": [ { "id": "A0A4X1SJX5", "url": "https://omabrowser.org/oma/group/A0A4X1SJX5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P62306-1", "protein_name": "Small nuclear ribonucleoprotein F", "gene_name": "SNRPF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "length": 86 }, "evidence": [ { "id": "A0A4X1SJX5", "url": "https://omabrowser.org/oma/group/A0A4X1SJX5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62307-1", "protein_name": "Small nuclear ribonucleoprotein F", "gene_name": "Snrpf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "length": 86 }, "evidence": [ { "id": "A0A4X1SJX5", "url": "https://omabrowser.org/oma/group/A0A4X1SJX5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q24297-1", "protein_name": "Small nuclear ribonucleoprotein F", "gene_name": "SmF", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSAGMPINPKPFLNGLTGKPVLVKLKWGQEYKGFLVSVDGYMNMQLANTEEVIEGSVTGNLGEVLIRCNNVLYIKGMEDDDEEGEMRD", "length": 88 }, "evidence": [ { "id": "A0A4X1SJX5", "url": "https://omabrowser.org/oma/group/A0A4X1SJX5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3T0Z8-1", "protein_name": "Small nuclear ribonucleoprotein F", "gene_name": "SNRPF", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "length": 86 }, "evidence": [ { "id": "A0A4X1SJX5", "url": "https://omabrowser.org/oma/group/A0A4X1SJX5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54XP2-1", "protein_name": "Small nuclear ribonucleoprotein F", "gene_name": "snrpf", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKIEALAPKPFLYDLKGKKIAVRLKWGGMEYRGILASVDSYMNLQLAATEEWIDGANKGPLGEVLIRCNNVLFVRGIDDEQQQSQQQQQE", "length": 91 }, "evidence": [ { "id": "A0A4X1SJX5", "url": "https://omabrowser.org/oma/group/A0A4X1SJX5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9SUM2-1", "protein_name": "Probable small nuclear ribonucleoprotein F", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATIPVNPKPFLNNLTGKTVIVKLKWGMEYKGFLASVDSYMNLQLGNTEEYIDGQLTGNLGEILIRCNNVLYVRGVPEDEELEDADQD", "length": 88 }, "evidence": [ { "id": "A0A4X1SJX5", "url": "https://omabrowser.org/oma/group/A0A4X1SJX5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 14, "go_terms": [ { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "methylosome", "id": "GO:0034709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034709", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "pICln-Sm protein complex", "id": "GO:0034715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034715", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "U4 snRNP", "id": "GO:0005687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005687", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "SMN-Sm protein complex", "id": "GO:0034719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034719", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "U7 snRNP", "id": "GO:0005683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005683", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "Sm-like protein family complex", "id": "GO:0120114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120114", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SJX5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SJX5" }, { "id": "PS52002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sm", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 78, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SK65-1", "uniprot_ac": "A0A4X1SK65", "uniprot_id": "A0A4X1SK65_PIG", "mass": { "chemical_mass": 29945.0, "monoisotopic_mass": 29945.0 }, "refseq": {}, "gene_names": [ { "name": "RPS3A", "type": "recommended", "evidence": [ { "id": "A0A4X1SK65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein eS1", "type": "recommended", "evidence": [ { "id": "A0A4X1SK65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role during erythropoiesis through regulation of transcription factor DDIT3.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65#function" }, { "database": "HAMAP", "id": "MF_03122", "url": "https://hamap.expasy.org/signature/MF_03122" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPS3A", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65", "locus": { "chromosome": "8", "start_pos": 77889607, "end_pos": 78023346, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009019", "url": "https://www.ensembl.org/id/ENSSSCG00000009019" } ] } } ], "crossref": [ { "id": "A0A4X1SK65", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SK65", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TRFKGHE", "url": "https://omabrowser.org/oma/group/TRFKGHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11830", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11830", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01015", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01015", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SK65-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGSSSGKATGDETGAKVERADGYEPPVQESV", "length": 264, "header": "tr|A0A4X1SK65-1|A0A4X1SK65_PIG Isoform 1 of Small ribosomal subunit protein eS1 OS=Sus scrofa OX=9823 GN=RPS3A PE=1 SV=1 CANONICAL=A0A4X1SK65-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SK65-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65/entry#A0A4X1SK65-1", "sequence": { "sequence": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGSSSGKATGDETGAKVERADGYEPPVQESV", "length": 264, "header": "tr|A0A4X1SK65-1|A0A4X1SK65_PIG Isoform 1 of Small ribosomal subunit protein eS1 OS=Sus scrofa OX=9823 GN=RPS3A PE=1 SV=1 CANONICAL=A0A4X1SK65-1" }, "locus": { "chromosome": "8", "start_pos": 77893716, "end_pos": 77889660, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009878.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009878.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009623.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009623.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-SSC-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HKG8-1", "protein_name": "Small ribosomal subunit protein eS1", "gene_name": "Rps3a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGGSSGKTTGDETGAKVERADGYEPPVQESV", "length": 264 }, "evidence": [ { "id": "A0A4X1SK65", "url": "https://omabrowser.org/oma/group/A0A4X1SK65/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P23248-1", "protein_name": "Small ribosomal subunit protein eS1B", "gene_name": "RPS1B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVGKNKRLSRGKKGLKKKVVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKNASDALKGRVVEVCLADLQGSEDHSFRKVKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTREVQNSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHGEGSGEEKGKKVSGFKDEVLETV", "length": 255 }, "evidence": [ { "id": "A0A4X1SK65", "url": "https://omabrowser.org/oma/group/A0A4X1SK65/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P49242-1", "protein_name": "Small ribosomal subunit protein eS1", "gene_name": "Rps3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGGSSGKTTGDETGAKVERADGYEPPVQESV", "length": 264 }, "evidence": [ { "id": "A0A4X1SK65", "url": "https://omabrowser.org/oma/group/A0A4X1SK65/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P55830-1", "protein_name": "Small ribosomal subunit protein eS1", "gene_name": "RpS3A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAVGKNKGLSKGGKKGGKKKVVDPFSRKDWYDVKAPNMFQTRQIGKTLVNRTQGQRIASDYLKGRVFEVSLADLQKDIDPERSFRKFRLIAEDVQDRNVLCNFHGMDLTTDKYRSMVKKWQTLIEAIVEAKTVDGYLLRVFCIGFTAKDQQSQRKTCYAQQSQVRKIRARMTDIITNEVSGADLKQLVNKLALDSIAKDIEKSCQRIYPLHDVYIRKVKVLKKPRFDVSKLLELHGDGGGKSVEAVVSSEGAVIDRPEGYEPPVQEAV", "length": 268 }, "evidence": [ { "id": "A0A4X1SK65", "url": "https://omabrowser.org/oma/group/A0A4X1SK65/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P61247-1", "protein_name": "Small ribosomal subunit protein eS1", "gene_name": "RPS3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGSSSGKATGDETGAKVERADGYEPPVQESV", "length": 264 }, "evidence": [ { "id": "A0A4X1SK65", "url": "https://omabrowser.org/oma/group/A0A4X1SK65/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97351-1", "protein_name": "Small ribosomal subunit protein eS1", "gene_name": "Rps3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGGSSGKAAGDETGAKVERADGYEPPVQESV", "length": 264 }, "evidence": [ { "id": "A0A4X1SK65", "url": "https://omabrowser.org/oma/group/A0A4X1SK65/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54ZW5-1", "protein_name": "Small ribosomal subunit protein eS1", "gene_name": "rps3a", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MADKKKKGSKKGGKKVDPFTRKEWYVVRAPTQFFKSPADNKVGFTPVNRTQGTKLASDGLKGRVYEVSLADMKDDESQVFRKIKLRAEEVEGRNVLTNFYGMDLTSDKLRSLIHKWSTLIECFVDVKTTDGYFLRVFAICFTKKGESQKKKTSYAKTSRVKAIRKKMVDILTETVSSNDLKTVVDYLIGVSLNGVTTNASGFAPTLAEKIRIEGSSIFPIHNVFIRKVKVLKTPKVDAAKLSELYASSATSTIAPTEEVGTAVERTEETTTTA", "length": 273 }, "evidence": [ { "id": "A0A4X1SK65", "url": "https://omabrowser.org/oma/group/A0A4X1SK65/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q56JV9-1", "protein_name": "Small ribosomal subunit protein eS1", "gene_name": "RPS3A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGSSSGKATGDETGAKVERADGYEPPVQESV", "length": 264 }, "evidence": [ { "id": "A0A4X1SK65", "url": "https://omabrowser.org/oma/group/A0A4X1SK65/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PBY1-1", "protein_name": "Small ribosomal subunit protein eS1", "gene_name": "rps3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVGKNKRLTKGGKKGAKKKIVDPFSKKDWYDVKAPAMFNIRNLGKTLVTRTQGTRIASDGLKGRVFEVSLADLQNDEVAFRKFKLVTEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRTNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSVGKDIEKACQSIYPLHDVYVRKVKMLKKPKFELGKLMELHGEGGSTSAAAKPAEGDTGAKVERADGYEPPIQESV", "length": 267 }, "evidence": [ { "id": "A0A4X1SK65", "url": "https://omabrowser.org/oma/group/A0A4X1SK65/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CAV0-1", "protein_name": "Small ribosomal subunit protein eS1z", "gene_name": "RPS3AA", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAVGKNKRISKGRKGGKKKAVDPFSKKDWYDVKAPSIFTHRNVGKTLVSRTQGTKIASEGLKHRVFEVSLADLQGDEDNAYRKIRLRAEDVQGRNVLCQFWGMDFTTDKLRSLVKKWQTLIEAHVDVKTTDSYTLRLFCIAFTKRRANQVKRTCYAQSSQIRQIRRKMRDIMVREASSCDLKDLVAKFIPEAIGREIEKATQGIYPLQNVFIRKVKILKAPKFDLGKLMDVHGDYSAEDVGVKVDRPADEMAVEEPTEIIGA", "length": 262 }, "evidence": [ { "id": "A0A4X1SK65", "url": "https://omabrowser.org/oma/group/A0A4X1SK65/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA 5'-UTR binding", "id": "GO:0048027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048027", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SK65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SK65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SL39-1", "uniprot_ac": "A0A4X1SL39", "uniprot_id": "A0A4X1SL39_PIG", "mass": { "chemical_mass": 56750.0, "monoisotopic_mass": 56750.0 }, "refseq": { "ac": "XP_005663592", "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663592" }, "gene_names": [ { "name": "PDZK1", "type": "recommended", "evidence": [ { "id": "A0A4X1SL39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ] }, { "name": "PDZK1", "type": "synonym", "evidence": [ { "id": "XP_005663592", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663592" } ] } ], "protein_names": [ { "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF3", "type": "recommended", "evidence": [ { "id": "A0A4X1SL39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39/entry#names_and_taxonomy" } ] }, { "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF3", "type": "synonym", "evidence": [ { "id": "XP_005663592", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663592" } ] }, { "name": "Na(+)/H(+) exchanger regulatory factor 3", "type": "synonym", "evidence": [ { "id": "A0A4X1SL39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39/entry#names_and_taxonomy" } ] }, { "name": "PDZ domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A4X1SL39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39/entry#names_and_taxonomy" } ] }, { "name": "Sodium-hydrogen exchanger regulatory factor 3", "type": "synonym", "evidence": [ { "id": "A0A4X1SL39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PDZK1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39", "locus": { "chromosome": "4", "start_pos": 99657161, "end_pos": 99625080, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006693", "url": "https://www.ensembl.org/id/ENSSSCG00000006693" } ] } } ], "crossref": [ { "id": "A0A4X1SL39", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SL39", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06768", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06768", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152549", "url": "https://www.ncbi.nlm.nih.gov/gene/100152549", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152549", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152549", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SL39", "url": "https://www.orthodb.org/?gene=A0A4X1SL39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14191", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14191", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14191:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14191:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005663592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663592", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SKZ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SKZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SKZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SKZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SL11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SL11-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SL39-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1JN15", "url": "https://www.uniprot.org/uniprotkb/A0A8D1JN15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1JN15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1JN15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSFKPRECNLSKQEGQSYGFFLRIEKDTDGHLVRVVEKGSPAEKAGLQDGDRVLRINGVFVDKKEHMQVVDLVRKSGNSVTLLVLDGDSYEKAMKKQVDLKELGQSQESSLNDKKLPSVMNGGAQTWTQPRLCYLVKEGSSYGFSLKTVQDKKGVYMTDIKPQGVAMKAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKYHSEQKIKVKRETASLKLLPHQPRIVEMKKGSNGYGFYLRAGPEQKGQIVKDIDSRSPAEEAGLKNNDLVVAVNGECVESLDHDSVVEMIRKGGDQTSLLVVDKETDNMYKLARISPFLYYQSQELPNGSVTEAPAPAPLEVSSPDTTEEVGDHKPKLCRLVKGEDGYGFHLNAIRGQPGSFVKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSMADPLDDAPDSKEGTLEESEHDSHTAKERANSTASHSSSNSEDTEM", "length": 516, "header": "tr|A0A4X1SL39-1|A0A4X1SL39_PIG Isoform 1 of Na(+)/H(+) exchange regulatory cofactor NHE-RF3 OS=Sus scrofa OX=9823 GN=PDZK1 PE=1 SV=1 CANONICAL=A0A4X1SL39-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SKZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39/entry#A0A4X1SKZ2-1", "sequence": { "sequence": "MASSFKPRECNLSKQEGQSYGFFLRIEKDTDGHLVRVVEKGSPAEKAGLQDGDRVLRINGVFVDKKEHMQVVDLVRKSGNSVTLLVLDGDSYEKAMKKQVDLKELGQSQESSLNDKKLPSVMNGGAQTWTQPRLCYLVKEGSSYGFSLKTVQDKKGVYMTDIKPQGVAMKAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKYHSEQKIKVKRETASLKLLPHQPRIVEMKKGSNGYGFYLRAGPEQKGQIVKDIDSRSPAEEAGLKNNDLVVAVNGECVESLDHDSVVEMIRKGGDQTSLLVVDKETDNMYKLARISPFLYYQSQELPNGSVTEAPAPAPLEVSSPDTTEEVGDHKPKLCRLVKGEDGYGFHLNAIRGQPGSFVKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKMTPLILKKERWRNRSMTRTRQKKEPTVQPLILLPILKIQRCDENK", "length": 480, "header": "tr|A0A4X1SKZ2-1|A0A4X1SKZ2_PIG Computationally mapped isoform of Na(+)/H(+) exchange regulatory cofactor NHE-RF3 OS=Sus scrofa OX=9823 GN=PDZK1 PE=1 SV=1 CANONICAL=A0A4X1SL39-1" }, "locus": { "chromosome": "4", "start_pos": 99656745, "end_pos": 99642163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056199.2", "url": "https://www.ensembl.org/id/ENSSSCT00000056199.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053364.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053364.1" } ] } }, { "isoform_ac": "A0A4X1SL11-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39/entry#A0A4X1SL11-1", "sequence": { "sequence": "MASSFKPRECNLSKQEGQSYGFFLRIEKDTDGHLVRVVEKGSPAEKAGLQDGDRVLRINGVFVDKKEHMQVVDLVRKSGNSVTLLVLDGDSYEKAMKKQVDLKELGQSQESSLNDKKLPSVMNGGAQTWTQPRLCYLVKEGSSYGFSLKTVQGQIVKDIDSRSPAEEAGLKNNDLVVAVNGECVESLDHDSVVEMIRKGGDQTSLLVVDKETDNMYKLARISPFLYYQSQELPNGSVTEAPAPAPLEVSSPDTTEEVGDHKPKLCRLVKGEDGYGFHLNAIRGQPGSFVKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSMADPLDDAPDSKEGTLEESEHDSHTAKERANSTASHSSSNSEDTEM", "length": 405, "header": "tr|A0A4X1SL11-1|A0A4X1SL11_PIG Computationally mapped isoform of PDZ domain containing 1 OS=Sus scrofa OX=9823 GN=PDZK1 PE=1 SV=1 CANONICAL=A0A4X1SL39-1" }, "locus": { "chromosome": "4", "start_pos": 99656732, "end_pos": 99642163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077146.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077146.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065059.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065059.1" } ] } }, { "isoform_ac": "A0A4X1SL39-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39/entry#A0A4X1SL39-1", "sequence": { "sequence": "MASSFKPRECNLSKQEGQSYGFFLRIEKDTDGHLVRVVEKGSPAEKAGLQDGDRVLRINGVFVDKKEHMQVVDLVRKSGNSVTLLVLDGDSYEKAMKKQVDLKELGQSQESSLNDKKLPSVMNGGAQTWTQPRLCYLVKEGSSYGFSLKTVQDKKGVYMTDIKPQGVAMKAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKYHSEQKIKVKRETASLKLLPHQPRIVEMKKGSNGYGFYLRAGPEQKGQIVKDIDSRSPAEEAGLKNNDLVVAVNGECVESLDHDSVVEMIRKGGDQTSLLVVDKETDNMYKLARISPFLYYQSQELPNGSVTEAPAPAPLEVSSPDTTEEVGDHKPKLCRLVKGEDGYGFHLNAIRGQPGSFVKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSMADPLDDAPDSKEGTLEESEHDSHTAKERANSTASHSSSNSEDTEM", "length": 516, "header": "tr|A0A4X1SL39-1|A0A4X1SL39_PIG Isoform 1 of Na(+)/H(+) exchange regulatory cofactor NHE-RF3 OS=Sus scrofa OX=9823 GN=PDZK1 PE=1 SV=1 CANONICAL=A0A4X1SL39-1" }, "locus": { "chromosome": "4", "start_pos": 99656732, "end_pos": 99642163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007332.3", "url": "https://www.ensembl.org/id/ENSSSCT00000007332.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007137.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007137.3" } ] } }, { "isoform_ac": "A0A8D1JN15-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39/entry#A0A8D1JN15-1", "sequence": { "sequence": "MPRTCTEMASSFKPRECNLSKQEGQSYGFFLRIEKDTDGHLVRVVEKGSPAEKAGLQDGDRVLRINGVFVDKKEHMQVVDLVRKSGNSVTLLVLDGDSYEKAMKKQVDLKELGQSQESSLNDKKLPSVMNGGAQTWTQPRLCYLVKEGSSYGFSLKTVQDKKGVYMTDIKPQGVAMKAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKYHSEQKIKVKRETASLKLLPHQPRIVEMKKGSNGYGFYLRAGPEQKGQIVKDIDSRSPAEEAGLKNNDLVVAVNGECVESLDHDSVVEMIRKGGDQTSLLVVDKETDNMYKLARISPFLYYQSQELPNGSVTEAPAPAPLEVSSPDTTEEVGDHKPKLCRLVKGEDGYGFHLNAIRGQPGSFVKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSMADPLDDAPDSKEGTLEESEHDSHTAKERVSDDTFLLMI", "length": 516, "header": "tr|A0A8D1JN15-1|A0A4X1SL39_PIG Computationally mapped isoform of Na(+)/H(+) exchange regulatory cofactor NHE-RF3 OS=Sus scrofa OX=9823 GN=PDZK1 PE=1 SV=1 CANONICAL=A0A4X1SL39-1" }, "locus": { "chromosome": "4", "start_pos": 99654876, "end_pos": 99641785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030375.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030375.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024258.3", "url": "https://www.ensembl.org/id/ENSSSCP00000024258.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1JN15", "url": "https://www.uniprot.org/uniprotkb/A0A8D1JN15" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152549", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152549", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ], "pmid": "" }, { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ], "pmid": "" }, { "name": "transporter activator activity", "id": "GO:0141109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141109", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ], "pmid": "" }, { "name": "carnitine transmembrane transport", "id": "GO:1902603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902603", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ], "pmid": "" }, { "name": "positive regulation of protein localization to membrane", "id": "GO:1905477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905477", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SL39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL39" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 90, "start_aa": "Glu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 501, "end_pos": 503 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SM32-1", "uniprot_ac": "A0A4X1SM32", "uniprot_id": "A0A4X1SM32_PIG", "mass": { "chemical_mass": 24256.0, "monoisotopic_mass": 24256.0 }, "refseq": { "ac": "XP_001929508", "name": "beta-crystallin B3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929508" }, "gene_names": [ { "name": "CRYBB3", "type": "recommended", "evidence": [ { "id": "A0A4X1SM32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32" } ] }, { "name": "CRYBB3", "type": "synonym", "evidence": [ { "id": "XP_001929508", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929508" } ] } ], "protein_names": [ { "name": "Beta-crystallin B3", "type": "recommended", "evidence": [ { "id": "A0A4X1SM32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32/entry#names_and_taxonomy" } ] }, { "name": "Beta-B3 crystallin", "type": "synonym", "evidence": [ { "id": "A0A4X1SM32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32/entry#names_and_taxonomy" } ] }, { "name": "beta-crystallin B3", "type": "synonym", "evidence": [ { "id": "XP_001929508", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929508" } ] } ], "function": [ { "annotation": "Crystallins are the dominant structural components of the vertebrate eye lens.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL10#function" }, { "database": "UniProtKB", "id": "ARBA00003689", "url": "https://www.uniprot.org/uniprotkb/ARBA00003689#function" }, { "database": "UniProtKB", "id": "A0A4X1SM32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CRYBB3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32", "locus": { "chromosome": "14", "start_pos": 43199626, "end_pos": 43193060, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009954", "url": "https://www.ensembl.org/id/ENSSSCG00000009954" } ] } } ], "crossref": [ { "id": "A0A4X1SM32", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SM32", "database": "AlphaFoldDB", "categories": [] }, { "id": "100157434", "url": "https://www.ncbi.nlm.nih.gov/gene/100157434", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157434", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157434", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RIRDRKW", "url": "https://omabrowser.org/oma/group/RIRDRKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SM32", "url": "https://www.orthodb.org/?gene=A0A4X1SM32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001929508", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929508", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SL10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SL10-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SM32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SM32-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEQHGTPEQAAAGKSHGGLGGGYKVIVYEMENFQGKRCELSAECPNLTESLLEKVGSIQVESGPWLAFERRAFRGEQFVLEKGDYPRWDAWSNSHHSDSLLSLRPLHIDGPDHKLHLFENPAFGGRKMEIVDDDVPSLWAHGFQDRVASIRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDANQPQLQSVRRIRDQKWHKRGCFLSS", "length": 211, "header": "tr|A0A4X1SM32-1|A0A4X1SM32_PIG Isoform 1 of Beta-crystallin B3 OS=Sus scrofa OX=9823 GN=CRYBB3 PE=1 SV=1 CANONICAL=A0A4X1SM32-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SL10-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32/entry#A0A4X1SL10-1", "sequence": { "sequence": "MAEQHGTPEQAAAGKSHGGLGGGYKVIVYEMENFQGKRCELSAECPNLTESLLEKVGSIQVESGPWLAFERRAFRGEQFVLEKGDYPRWDAWSNSHHSDSLLSLRPLHIVGWLR", "length": 114, "header": "tr|A0A4X1SL10-1|A0A4X1SM32_PIG Computationally mapped isoform of Beta-crystallin B3 OS=Sus scrofa OX=9823 GN=CRYBB3 PE=1 SV=1 CANONICAL=A0A4X1SM32-1" }, "locus": { "chromosome": "14", "start_pos": 43199331, "end_pos": 43194705, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099615.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099615.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075392.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075392.1" } ] } }, { "isoform_ac": "A0A4X1SM32-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32/entry#A0A4X1SM32-1", "sequence": { "sequence": "MAEQHGTPEQAAAGKSHGGLGGGYKVIVYEMENFQGKRCELSAECPNLTESLLEKVGSIQVESGPWLAFERRAFRGEQFVLEKGDYPRWDAWSNSHHSDSLLSLRPLHIDGPDHKLHLFENPAFGGRKMEIVDDDVPSLWAHGFQDRVASIRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDANQPQLQSVRRIRDQKWHKRGCFLSS", "length": 211, "header": "tr|A0A4X1SM32-1|A0A4X1SM32_PIG Isoform 1 of Beta-crystallin B3 OS=Sus scrofa OX=9823 GN=CRYBB3 PE=1 SV=1 CANONICAL=A0A4X1SM32-1" }, "locus": { "chromosome": "14", "start_pos": 43199479, "end_pos": 43194705, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010909.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010909.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010624.2", "url": "https://www.ensembl.org/id/ENSSSCP00000010624.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL10" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157434", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157434", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N3U7-1", "protein_name": "Beta-crystallin B3", "gene_name": "Crybb3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEQHSTPEQAAAGKSHGGLGGSYKVTVYELENFQGKRCELSAECPNLTDSLLEKVGSIQVESGPWLAFERRAFRGEQFVLEKGDYPRWDAWSSSRRNDILLSLRPLHIDGPDHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASIRVINGTWVGYEFPGYRGRQYVFERGEFRHWNEWDANQPQLQSVRRIRDQKWHKRGCFLSS", "length": 211 }, "evidence": [ { "id": "A0A4X1SM32", "url": "https://omabrowser.org/oma/group/A0A4X1SM32/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P02524-1", "protein_name": "Beta-crystallin B3", "gene_name": "Crybb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEQHGAPEQAAASKSHGGLGGSYKVTVYELENFQGKRCELSAECPNLTESLLQKVGSIQVESGPWLAFERRAFRGEQFVLEKGDYPRWDAWSSSRRSDILLSLRPLHIDGPDHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASIRVINGTWVGYEFPGYRGRQYVFERGEFRHWNEWDANQPQLQSVRRIRDQKWHKRGCFLSS", "length": 211 }, "evidence": [ { "id": "A0A4X1SM32", "url": "https://omabrowser.org/oma/group/A0A4X1SM32/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P19141-1", "protein_name": "Beta-crystallin B3", "gene_name": "CRYBB3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEQHSTPEQAAAGKSHGGLGGSYKVIVYEMENFQGKRCELTAECPNLTESLLEKVGSIQVESGPWLAFERRAFRGEQYVLEKGDYPRWDAWSNSHHSDSLLSLRPLHIDGPDHKLHLFENPAFGGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDANQPQLQSVRRIRDQKWHKRGVFLSS", "length": 211 }, "evidence": [ { "id": "A0A4X1SM32", "url": "https://omabrowser.org/oma/group/A0A4X1SM32/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P26998-1", "protein_name": "Beta-crystallin B3", "gene_name": "CRYBB3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS", "length": 211 }, "evidence": [ { "id": "A0A4X1SM32", "url": "https://omabrowser.org/oma/group/A0A4X1SM32/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P55165-1", "protein_name": "Beta-crystallin B3", "gene_name": "CRYBB3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTEQQSPPEQMVTGEGAGERGGNYKITIYELENFQGRRCELSEELPNVVDKALEKVGSIQVESGPWLGFERQAFAGEQFVLEKGDYPRWDSWSNSHNSDSLMSLRPLQIDSPDHKIHLFENAGYTGRKMEIVDDDVPSLWAHGFQDRVASVRALNGTWVGYEYPGYRGRQHVFEKGEYRHWNEWDANQPLMQSVRRVRDQQWHQRGSFENS", "length": 211 }, "evidence": [ { "id": "A0A4X1SM32", "url": "https://omabrowser.org/oma/group/A0A4X1SM32/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9JJU9-1", "protein_name": "Beta-crystallin B3", "gene_name": "Crybb3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEQHGAPEQAAAGKSHGGLGGSYKVTVYELENFQGKRCELSAECPNLTDSLLEKVGSIQVESGPWLAFERRAFRGEQFVLEKGDYPRWDAWSSSRRSDILLSLRPLHIDGPDHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASIRVINGTWVGYEFPGYRGRQYVFERGEFRHWNEWDANQPQLQSVRRIRDQKWHKRGCFLSS", "length": 211 }, "evidence": [ { "id": "A0A4X1SM32", "url": "https://omabrowser.org/oma/group/A0A4X1SM32/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of eye lens", "id": "GO:0005212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005212", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32" } ], "pmid": "" }, { "name": "lens development in camera-type eye", "id": "GO:0002088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002088", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SM32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM32" }, { "id": "PS50915", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50915" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta/gamma crystallin 'Greek key'", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 63, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SL33-1", "uniprot_ac": "A0A4X1SL33", "uniprot_id": "A0A4X1SL33_PIG", "mass": { "chemical_mass": 17066.0, "monoisotopic_mass": 17066.0 }, "refseq": {}, "gene_names": [ { "name": "TXNL4B", "type": "recommended", "evidence": [ { "id": "A0A4X1SL33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33" } ] } ], "protein_names": [ { "name": "Thioredoxin-like protein", "type": "recommended", "evidence": [ { "id": "A0A4X1SL33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL33", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33#function" }, { "database": "UniProtKB", "id": "ARBA00060348", "url": "https://www.uniprot.org/uniprotkb/ARBA00060348#function" } ] }, { "annotation": "Plays role in pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL33", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33#function" }, { "database": "UniProtKB", "id": "PIRNR017199", "url": "https://www.uniprot.org/uniprotkb/PIRNR017199#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL33", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TXNL4B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33", "locus": { "chromosome": "6", "start_pos": 14985474, "end_pos": 14998017, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000025218", "url": "https://www.ensembl.org/id/ENSSSCG00000025218" } ] } } ], "crossref": [ { "id": "cd02986", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02986", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NIPKYEL", "url": "https://omabrowser.org/oma/group/NIPKYEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12052", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12052", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12052:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12052:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1SL33", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SL33-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1ELN9", "url": "https://www.uniprot.org/uniprotkb/A0A8D1ELN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1ELN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1ELN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFLLPKLSSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMATIYLVDVDQTPVYTHYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIYRGAMRGKLIVQSPIDPKNIPKYDLLYQDI", "length": 149, "header": "tr|A0A4X1SL33-1|A0A4X1SL33_PIG Isoform 1 of Thioredoxin-like protein OS=Sus scrofa OX=9823 GN=TXNL4B PE=3 SV=1 CANONICAL=A0A4X1SL33-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SL33-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33/entry#A0A4X1SL33-1", "sequence": { "sequence": "MSFLLPKLSSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMATIYLVDVDQTPVYTHYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIYRGAMRGKLIVQSPIDPKNIPKYDLLYQDI", "length": 149, "header": "tr|A0A4X1SL33-1|A0A4X1SL33_PIG Isoform 1 of Thioredoxin-like protein OS=Sus scrofa OX=9823 GN=TXNL4B PE=3 SV=1 CANONICAL=A0A4X1SL33-1" }, "locus": { "chromosome": "6", "start_pos": 14994410, "end_pos": 14988685, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039122.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039122.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043076.3", "url": "https://www.ensembl.org/id/ENSSSCP00000043076.3" } ] } }, { "isoform_ac": "A0A8D1ELN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33/entry#A0A8D1ELN9-1", "sequence": { "sequence": "MSFLLPKLSSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDIVPRSHQVCGKFQNQTRLYRFD", "length": 65, "header": "tr|A0A8D1ELN9-1|A0A4X1SL33_PIG Computationally mapped isoform of Thioredoxin-like protein OS=Sus scrofa OX=9823 GN=TXNL4B PE=3 SV=1 CANONICAL=A0A4X1SL33-1" }, "locus": { "chromosome": "6", "start_pos": 14994410, "end_pos": 14988785, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025187.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025187.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024199.3", "url": "https://www.ensembl.org/id/ENSSSCP00000024199.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1ELN9", "url": "https://www.uniprot.org/uniprotkb/A0A8D1ELN9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XJP6-1", "protein_name": "Sentrin-specific protease 7", "gene_name": "SENP7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEGRPSPSSHVSFRIPKKKPNNKSEDVQVQSPLARLPGSQHWDYPLREWRLSASNRETSTKGRRQRDCDRCSSNDEESIGQPKVILTNVLRTKIGRKYTQAQPKTDANFSDAGKLQSNQPPSSSVASLKIWQILNPALHSPFLSKRQPQVILTNVLRTRIGRKYVDSHILIDSNLSDAEKLQLGQLASSSVASAQTCQILSSPHESSFLSERSEHCLTKSDVNLSKESERGNVVLTFRRRKLEKKENKSSDELDKKRKNMNSTSSSWKGSSSLDSEKRKRRFSGHISDDCKERIPEKSLLRSKEQRLSSTRSSGCRTPCEDEQDHRSDLVQDSVAQTLERDCKDTPTNNQLRPAHSCSEEAGSDSAPSDLSEKQLIAVSPQVSTIRKVKTDTSQYLNKLRNRNCRSNRPLVSADPIVLSSDDEDRSSEPKEEEGLSEPKCMEQLQDNITDVQEIEQQSDVRFSEKLMEDNVESHTEQLLTKSDDDKCPTNLPSGNIHSEQMKPGLDFEFDSIYIGIFKWSSTGPVRFMTKYITIPFQVALNKNIKLTVDTLDVRRFGLWRNDGGCSSTTVIFIWLSVDYLEKIETQLGKRVSSEPSKCSEFIFLELSQPLPEQDVVRLSELITEISKKNRAPDLLELLSLKQALLLFKDLSPEESSFISSREDLLKQCATKESISFAQEPTFQKPKPKVARPSYALANKQNSGCYSISLSSAPNEEWKEVGESGAVKNLIVYPPPPAKGGLGVTREDLKCLEYGEFLNDVIIDFYLKYLLLEKAPKHLAERTHIFSSFFYKCLTRTEKFSEEDPKVSVAQRRHKRVRTWTRHINIFSKDYIFVPVNEESHWYMAVICFPWLEETVYEEHPHQNSLNLSPLQSENKSEDSVIGSVLAYPEEEMDANRILFSKGGNESAASASGLDSGISKISLNNSKRQVCKRPCILILDSLKAGSVQKTVQVLREYLEVEWEVKRKTRREFSKSTMIDFYPRVPKQDNSSDCGVYLLQYVESFFQNPIVDFEQPVHLEKWFPRQVIRSKREEIQDLILQLHFQQLRGSRS", "length": 1050 }, "evidence": [ { "id": "A0A4X1SL33", "url": "https://omabrowser.org/oma/group/A0A4X1SL33/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HAH4-1", "protein_name": "Thioredoxin-like protein", "gene_name": "Txnl4b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSADLSKMAAIYLVDVDHTPVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFMDLIEVIYRGAMRGKLIVQSPIDPKNIPKYDLLYQDI", "length": 149 }, "evidence": [ { "id": "A0A4X1SL33", "url": "https://omabrowser.org/oma/group/A0A4X1SL33/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5FVI5-1", "protein_name": "Thioredoxin-like protein", "gene_name": "Txnl4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSADLSKMATIYLVDVDQTPVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIYRGAMRGKLIVQSPIDPKNIPKYDLLYQDI", "length": 149 }, "evidence": [ { "id": "A0A4X1SL33", "url": "https://omabrowser.org/oma/group/A0A4X1SL33/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BUH1-1", "protein_name": "Thioredoxin-like protein 4B", "gene_name": "Txnl4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSADLSKMAAIYLVDVDHTPVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIYRGAMRGKLIVQSPIDPKNVPKYDLLYQDI", "length": 149 }, "evidence": [ { "id": "A0A4X1SL33", "url": "https://omabrowser.org/oma/group/A0A4X1SL33/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NX01-1", "protein_name": "Thioredoxin-like protein 4B", "gene_name": "TXNL4B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYLVDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIYRGAMRGKLIVQSPIDPKNIPKYDLLYQDI", "length": 149 }, "evidence": [ { "id": "A0A4X1SL33", "url": "https://omabrowser.org/oma/group/A0A4X1SL33/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL33", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL33", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL33", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL33", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SL33", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SL33" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SLI1-1", "uniprot_ac": "A0A4X1SLI1", "uniprot_id": "A0A4X1SLI1_PIG", "mass": { "chemical_mass": 33104.0, "monoisotopic_mass": 33104.0 }, "refseq": { "ac": "NP_001239317", "name": "putative monooxygenase p33MONOX", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239317" }, "gene_names": [ { "name": "KIAA1191", "type": "recommended", "evidence": [ { "id": "A0A4X1SLI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1" } ] }, { "name": "KIAA1191", "type": "synonym", "evidence": [ { "id": "NP_001239317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239317" } ] } ], "protein_names": [ { "name": "Putative monooxygenase p33MONOX", "type": "recommended", "evidence": [ { "id": "A0A4X1SLI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1/entry#names_and_taxonomy" } ] }, { "name": "putative monooxygenase p33MONOX", "type": "synonym", "evidence": [ { "id": "NP_001239317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239317" } ] } ], "function": [ { "annotation": "Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0MWC4", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MWC4#function" }, { "database": "UniProtKB", "id": "ARBA00025240", "url": "https://www.uniprot.org/uniprotkb/ARBA00025240#function" }, { "database": "UniProtKB", "id": "F1S387", "url": "https://www.uniprot.org/uniprotkb/F1S387#function" }, { "database": "UniProtKB", "id": "A0A4X1SLI1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLI1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KIAA1191", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1", "locus": { "chromosome": "2", "start_pos": 81539624, "end_pos": 81520408, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014060", "url": "https://www.ensembl.org/id/ENSSSCG00000014060" } ] } } ], "crossref": [ { "id": "ENSSSCG00000014060", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014060", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100524242", "url": "https://www.ncbi.nlm.nih.gov/gene/100524242", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524242", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524242", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TIQAYKG", "url": "https://omabrowser.org/oma/group/TIQAYKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SLI1", "url": "https://www.orthodb.org/?gene=A0A4X1SLI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28342:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28342:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001239317", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239317", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SLI1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SLI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0MWC4", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MWC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0MWC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MWC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F7R5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F7R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7R5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S387", "url": "https://www.uniprot.org/uniprotkb/F1S387", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S387-1", "url": "https://www.uniprot.org/uniprotkb/F1S387-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRQPEVPALEPSGPLGKMSLPIGMYRRAFSYDDALEDPAPMTPPPSDMGSIPWKPVIPERKYQHLAKVEEGDASASSPAVPLPPATDSADKVPVVKAKATHVIMSSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETNYLRVAEALHKLKLQSGEITREEKQPASTQSTPSSSPHSSPKQKSRGWFTSGSSIALPGPNLSAMDSGSGDKDRSSADKWGLFAPRSLQKSDSGSFATQVYRGAQKPSPMELIRVQATRMAEDPATFQPPKMDIPVIEGKKQLPRTHNLKPRDLNVLTPTGF", "length": 305, "header": "tr|A0A4X1SLI1-1|A0A4X1SLI1_PIG Isoform 1 of Putative monooxygenase p33MONOX OS=Sus scrofa OX=9823 GN=KIAA1191 PE=1 SV=1 CANONICAL=A0A4X1SLI1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SLI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1/entry#A0A4X1SLI1-1", "sequence": { "sequence": "MASRQPEVPALEPSGPLGKMSLPIGMYRRAFSYDDALEDPAPMTPPPSDMGSIPWKPVIPERKYQHLAKVEEGDASASSPAVPLPPATDSADKVPVVKAKATHVIMSSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETNYLRVAEALHKLKLQSGEITREEKQPASTQSTPSSSPHSSPKQKSRGWFTSGSSIALPGPNLSAMDSGSGDKDRSSADKWGLFAPRSLQKSDSGSFATQVYRGAQKPSPMELIRVQATRMAEDPATFQPPKMDIPVIEGKKQLPRTHNLKPRDLNVLTPTGF", "length": 305, "header": "tr|A0A4X1SLI1-1|A0A4X1SLI1_PIG Isoform 1 of Putative monooxygenase p33MONOX OS=Sus scrofa OX=9823 GN=KIAA1191 PE=1 SV=1 CANONICAL=A0A4X1SLI1-1" }, "locus": { "chromosome": "2", "start_pos": 81538178, "end_pos": 81525670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045492.2", "url": "https://www.ensembl.org/id/ENSSSCT00000045492.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055483.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055483.1" } ] } }, { "isoform_ac": "A0A8D0MWC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1/entry#A0A8D0MWC4-1", "sequence": { "sequence": "LVSLFLALEPSGPLGKMSLPIGMYRRAFSYDDALEDPAPMTPPPSDMGSIPWKPVIPERKYQHLAKVEEGDASASSPAVPLPPATDSADKVPVVKAKATHVIMSSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETNYLRVAEALHKLKLQSGEITREEKQPASTQSTPSSSPHSSPKQKSRGWFTSGSSIALPGPNLSAMDSGSGDKDRSSADKWGLFAPRSLQKSDSGSFATQVYRGAQKPSPMELIRVQATRMAEDPATFQPPKMDIPVIEGKKQLPRTHNLKPRDLNVLTPTGF", "length": 302, "header": "tr|A0A8D0MWC4-1|A0A4X1SLI1_PIG Computationally mapped isoform of Putative monooxygenase p33MONOX OS=Sus scrofa OX=9823 GN=KIAA1191 PE=1 SV=1 CANONICAL=A0A4X1SLI1-1" }, "locus": { "chromosome": "2", "start_pos": 81538178, "end_pos": 81529090, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058917.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058917.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054337.2", "url": "https://www.ensembl.org/id/ENSSSCP00000054337.2" } ] } }, { "isoform_ac": "A0A8W4F7R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1/entry#A0A8W4F7R5-1", "sequence": { "sequence": "MASRQPEVPETKAAEWRDNERGEAAGLHPVHPEQQPSLFPKAEVPRLVHFWFFHSLTWSQSQRHGFWKRG", "length": 70, "header": "tr|A0A8W4F7R5-1|A0A4X1SLI1_PIG Computationally mapped isoform of Putative monooxygenase p33MONOX OS=Sus scrofa OX=9823 GN=KIAA1191 PE=1 SV=1 CANONICAL=A0A4X1SLI1-1" }, "locus": { "chromosome": "2", "start_pos": 81537793, "end_pos": 81525670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095756.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095756.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075368.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075368.1" } ] } }, { "isoform_ac": "F1S387-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1/entry#F1S387-1", "sequence": { "sequence": "MASRQPEVPALEPSGPLGKMSLPIGMYRRAFSYDDALEDPAPMTPPPSDMGSIPWKPVIPERKYQHLAKVEEGDASASSPAVPLPPATDSADKVPVVKAKATHVIMSSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETNYLRVAEALHKLKLQSGEITREEKQPASTQSTPSSSPHSSPKQKSRGWFTSGSSIALPGPNLSAMDSGSGDKDRSSADKWGLFAPRSLQKSDSGSFATQVYRGAQKPSPMELIRVQATRMAEDPATFQPPKMDIPVIEGKKQLLGP", "length": 289, "header": "tr|F1S387-1|A0A4X1SLI1_PIG Computationally mapped isoform of Putative monooxygenase p33MONOX OS=Sus scrofa OX=9823 GN=KIAA1191 PE=1 SV=3 CANONICAL=A0A4X1SLI1-1" }, "locus": { "chromosome": "2", "start_pos": 81538131, "end_pos": 81525670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015359.4", "url": "https://www.ensembl.org/id/ENSSSCT00000015359.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014951.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014951.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 175, "start_aa": "Thr", "end_pos": 175, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr175", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 44, "start_aa": "Thr", "end_pos": 44, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr44", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0MWC4", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MWC4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524242", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524242", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IAV1-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "Kiaa1191", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASRQPEVPALAPSGPLGKMSLPIGMCRRAFSYDDALEDPAPMTPPPSDMGSIPWKPVIPERKYQHLDKTEEGAASVSSLAVTPATATDSSDKTPVVKAKATHVIMNSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETKYLRVAEALHKLKLQSGETTREEKPPASAQSTPSSTPHSSPKQKSRGWFPSGSSTALPGPNPHTMDSGSGNDKNSADKWSLFGARPLQRSDSGFAVQAYKGAPKPSPMELMRAQATRGGEDPATFKPPKIDVPVVEGKKPPPRTHNLKPRDLNVLTPTGF", "length": 303 }, "evidence": [ { "id": "A0A4X1SLI1", "url": "https://omabrowser.org/oma/group/A0A4X1SLI1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0YQF9-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "KIAA1191", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSARQPDAPALEQRGGALPGRMSLPLGVPRRAFSYDDALEDTAPMTPPPADLCANVLWKQPVIPERKYQELAKIEEGDANMNAPVITPSSSTESVNKVPVVKAKATHIIMNSLITKQTQESIQCFEQQAGLRDAGYTPHKGLTAEETKYHRVAEAVHKLKMQSGEMTKDDKQTSSAQSTPSSTPHSSPKHKNRGWFSQGSSASITAPDFVAMEAGGDRLPSERWSFFGPKAIQKSTNDPGGFTIQSYKGAQKPSPMELMRAQATRMTEDPVTFKPPKMDIPVTEGRKQSSHSHNIKPRDLNVLTPTGF", "length": 308 }, "evidence": [ { "id": "A0A4X1SLI1", "url": "https://omabrowser.org/oma/group/A0A4X1SLI1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A4QNZ7-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "p33monox", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVSRPGDLPALEAGPGSSEGLLGGMSIPAGMTRRALSYDDNLERPMSPPPSDINISNLWKRPVIPERKFARLAEEDESEGGVKQSASFESTKPIPVVKAKASSVMNSLIIKQTQESMQKFEKQAGLTDTGYTPHKGLNAEETRYHRLAESMHKLQMQSTDAKEERQPSSNQSTPAGTPQSSPKQKRRGWFNSQGSTASLTGSEMSTSSSSSVDLASAEGPIERWGVFGPRPQVSKSTTDPGTHPDTSGGFALQSYKGAQKPTPMEVMKAQATRLAEDPTNFKAPPKMEIPTMDGKRQVTRPHKLKHRDMNVLTPSGF", "length": 317 }, "evidence": [ { "id": "A0A4X1SLI1", "url": "https://omabrowser.org/oma/group/A0A4X1SLI1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3T044-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "P33MONOX", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASRQPEVPALEPSGPLGKMSLPIGMYRRAFSYDDALEDPTPMTPPPSDMGSIPWKPVIPERKYQDLAKVEEGEPSVSPPAPAPPPATDSAEKAPVVKAKATHVIMSSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETKYLRVAEALHKLKLQSGETAREERQPASTQSTPSSSPQASPKQKSRGWFTSGSATALPGPSLSTMDSGSGDKDRSSADKWSLFGPRSLQKSESGGFAIQAYKGAQKPSPMEVMRAQATRRAEEPATFKPPKMDIPVMEGTKQLPRAHSLKPRDLNVLTPTGF", "length": 305 }, "evidence": [ { "id": "A0A4X1SLI1", "url": "https://omabrowser.org/oma/group/A0A4X1SLI1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5U2R6-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "P33monox", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASRQPEVPPALAPSGPLSKMSLPIGMCRRAFSYDDALEDPAPMTPPPSDMGSIPWKPVIPERKYQHLDKTEEGAASVSSLAVTPSTATDSSDKAPVVKAKATHIIMNSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETKYLRVAEALHKLKLQSGETTREEKHPASAQSSPSSTPHSSPKQKSRGWFPSGSSTALPAPNPHSMDPGGGNDRNSADKWSLFGPRPLQKSDSGFAIQAYKGAPKPSPMEVMRAQATRAGEDPAVFKPPKMDVPVVEGKKQPPRTHNLKPRDLNVLTPTGF", "length": 304 }, "evidence": [ { "id": "A0A4X1SLI1", "url": "https://omabrowser.org/oma/group/A0A4X1SLI1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96A73-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "KIAA1191", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRQPEVPALEASAPLGKMSLPIGIYRRAVSYDDTLEDPAPMTPPPSDMGSVPWKPVIPERKYQHLAKVEEGEASLPSPAMTLSSAIDSVDKVPVVKAKATHVIMNSLITKQTQESIQHFERQAGLRDAGYTPHKGLTTEETKYLRVAEALHKLKLQSGEVTKEERQPASAQSTPSTTPHSSPKQRPRGWFTSGSSTALPGPNPSTMDSGSGDKDRNLSDKWSLFGPRSLQKYDSGSFATQAYRGAQKPSPLELIRAQANRMAEDPAALKPPKMDIPVMEGKKQPPRAHNLKPRDLNVLTPTGF", "length": 305 }, "evidence": [ { "id": "A0A4X1SLI1", "url": "https://omabrowser.org/oma/group/A0A4X1SLI1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBN4-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "P33monox", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRQPEVPALAPSGPLGKMSLPIGMCRRAFSYDDALEDPAPMTPPPSDMGSIPWKPVIPERKYQHLDKTEEGAASVSSLAVTPSPATDSSDKAPVVKAKATHVIMSSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETKYLRVAEALHKLKLQSGETAKEEKHPASAQSTPSSTPHASPKQKSRGWFPSGSSTALPAPNPHTMDPGSGNDRNSADKWSLFGPRPLQKSDSGFAIQAYKGAPRPSPMEVMRAQATRVGEDPATFKPPKMDVPMVEGKKQPLRTHNLKPRDLNVLTPTGF", "length": 303 }, "evidence": [ { "id": "A0A4X1SLI1", "url": "https://omabrowser.org/oma/group/A0A4X1SLI1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLI1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLI1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLI1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 44, 175 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 204, "end_pos": 206 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SLJ1-1", "uniprot_ac": "A0A4X1SLJ1", "uniprot_id": "A0A4X1SLJ1_PIG", "mass": { "chemical_mass": 13742.0, "monoisotopic_mass": 13742.0 }, "refseq": { "ac": "XP_003129967", "name": "40S ribosomal protein S25", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129967" }, "gene_names": [ { "name": "RPS25", "type": "recommended", "evidence": [ { "id": "A0A4X1SLJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1" } ] }, { "name": "RPS25", "type": "synonym", "evidence": [ { "id": "XP_003129967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129967" } ] } ], "protein_names": [ { "name": "40S ribosomal protein S25", "type": "recommended", "evidence": [ { "id": "A0A4X1SLJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S25", "type": "synonym", "evidence": [ { "id": "XP_003129967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129967" } ] } ], "function": [ { "annotation": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1#function" }, { "database": "UniProtKB", "id": "ARBA00045746", "url": "https://www.uniprot.org/uniprotkb/ARBA00045746#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPS25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1", "locus": { "chromosome": "9", "start_pos": 46235737, "end_pos": 46242432, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036296", "url": "https://www.ensembl.org/id/ENSSSCG00000036296" } ] } } ], "crossref": [ { "id": "A0A4X1SLJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SLJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100516385", "url": "https://www.ncbi.nlm.nih.gov/gene/100516385", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516385", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516385", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RIVHHSG", "url": "https://omabrowser.org/oma/group/RIVHHSG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SLJ1", "url": "https://www.orthodb.org/?gene=A0A4X1SLJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12850", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12850", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003129967", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129967", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SLJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA", "length": 125, "header": "tr|A0A4X1SLJ1-1|A0A4X1SLJ1_PIG Isoform 1 of 40S ribosomal protein S25 OS=Sus scrofa OX=9823 GN=RPS25 PE=1 SV=1 CANONICAL=A0A4X1SLJ1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SLJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1/entry#A0A4X1SLJ1-1", "sequence": { "sequence": "MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA", "length": 125, "header": "tr|A0A4X1SLJ1-1|A0A4X1SLJ1_PIG Isoform 1 of 40S ribosomal protein S25 OS=Sus scrofa OX=9823 GN=RPS25 PE=1 SV=1 CANONICAL=A0A4X1SLJ1-1" }, "locus": { "chromosome": "9", "start_pos": 46242035, "end_pos": 46239550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016469.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016469.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016026.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016026.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516385", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516385", "resource": "KEGG Pathway" }, { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-SSC-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I1P3-1", "protein_name": "40S ribosomal protein S25", "gene_name": "Rps25", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA", "length": 125 }, "evidence": [ { "id": "A0A4X1SLJ1", "url": "https://omabrowser.org/oma/group/A0A4X1SLJ1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P48588-1", "protein_name": "Small ribosomal subunit protein eS25", "gene_name": "RpS25", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPKKDAKSSAKQPQKTQKKKEGSGGGKAKKKKWSKGKVRDKLNNQVLFDKATYEKLYKEVPAYKLITPSVVSERLKIRGSLAKRALIELREKGLIKQVVQHHSQVIYTRATKGDEA", "length": 117 }, "evidence": [ { "id": "A0A4X1SLJ1", "url": "https://omabrowser.org/oma/group/A0A4X1SLJ1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P62851-1", "protein_name": "Small ribosomal subunit protein eS25", "gene_name": "RPS25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA", "length": 125 }, "evidence": [ { "id": "A0A4X1SLJ1", "url": "https://omabrowser.org/oma/group/A0A4X1SLJ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62852-1", "protein_name": "Small ribosomal subunit protein eS25", "gene_name": "Rps25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA", "length": 125 }, "evidence": [ { "id": "A0A4X1SLJ1", "url": "https://omabrowser.org/oma/group/A0A4X1SLJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P62853-1", "protein_name": "Small ribosomal subunit protein eS25", "gene_name": "Rps25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA", "length": 125 }, "evidence": [ { "id": "A0A4X1SLJ1", "url": "https://omabrowser.org/oma/group/A0A4X1SLJ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q03409-1", "protein_name": "Small ribosomal subunit protein eS25", "gene_name": "rps25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPKAAGGKSKQIQASKAAAKGSSGGAGRKKWSKGRSREKLNNAILFDKETYAKLLKEMPTAKVITTAVVSERMKCNGSLARRAIKELLSKGLIKQIIKGHGNGVYTKAQ", "length": 110 }, "evidence": [ { "id": "A0A4X1SLJ1", "url": "https://omabrowser.org/oma/group/A0A4X1SLJ1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q3E792-1", "protein_name": "Small ribosomal subunit protein eS25A", "gene_name": "RPS25A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPPKQQLSKAAKAAAALAGGKKSKKKWSKKSMKDRAQHAVILDQEKYDRILKEVPTYRYVSVSVLVDRLKIGGSLARIALRHLEKEGIIKPISKHSKQAIYTRATASE", "length": 108 }, "evidence": [ { "id": "A0A4X1SLJ1", "url": "https://omabrowser.org/oma/group/A0A4X1SLJ1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q56JX5-1", "protein_name": "Small ribosomal subunit protein eS25", "gene_name": "RPS25", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA", "length": 125 }, "evidence": [ { "id": "A0A4X1SLJ1", "url": "https://omabrowser.org/oma/group/A0A4X1SLJ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8GYL5-1", "protein_name": "Small ribosomal subunit protein eS25x", "gene_name": "RPS25D", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAPKKDKVPPPSSKPAKSGGGKQKKKKWSKGKQKEKVNNMVLFDQATYDKLLSEAPKFKLITPSILSDRLRINGSLARRAIRELMAKGTIRMVSAHSSQQIYTRATHG", "length": 108 }, "evidence": [ { "id": "A0A4X1SLJ1", "url": "https://omabrowser.org/oma/group/A0A4X1SLJ1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 24, "end_pos": 26 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SLK1-1", "uniprot_ac": "A0A4X1SLK1", "uniprot_id": "A0A4X1SLK1_PIG", "mass": { "chemical_mass": 32586.0, "monoisotopic_mass": 32586.0 }, "refseq": {}, "gene_names": [ { "name": "TREML1", "type": "recommended", "evidence": [ { "id": "A0A4X1SLK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1" } ] } ], "protein_names": [ { "name": "Triggering receptor expressed on myeloid cells like 1", "type": "synonym", "evidence": [ { "id": "A0A4X1SLK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLK1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TREML1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1", "locus": { "chromosome": "7", "start_pos": 36455634, "end_pos": 36460715, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001613", "url": "https://www.ensembl.org/id/ENSSSCG00000001613" } ] } } ], "crossref": [ { "id": "A0A4X1SLK1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SLK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WCQVLPE", "url": "https://omabrowser.org/oma/group/WCQVLPE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16423", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16423", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16423:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16423:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-SSC-198933", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-198933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SLK1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SLK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPHLLLLLLLGLAGQGSAGSLPELLQAPVGSSILVQCHYRPQDLRARKVWCRFLQGVCQPVVSSVVDRRTPAGSRIFLTDMGGGLLQVEMVTLQEEDAGEYGCLVEGASGPQTVHKVTLDVLPAAPGLEEEEETYQVGSLADSSSDPAGSASPLNPGLDKKSRLLIWGAVFLLGLLVVAVVLFTMMARRKGNRLGVCGQFQSSGISGLASSPGVHHSGDTGPAADLPSDIPYVRLDSPPSFDNTTYTNLPLDPLSEKPPSPSSFPPLPPKVMTSKPVTYATVVFPEGDKSGRASCEPVQDPPNSQTPPS", "length": 310, "header": "tr|A0A4X1SLK1-1|A0A4X1SLK1_PIG Isoform 1 of Triggering receptor expressed on myeloid cells like 1 OS=Sus scrofa OX=9823 GN=TREML1 PE=4 SV=1 CANONICAL=A0A4X1SLK1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SLK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1/entry#A0A4X1SLK1-1", "sequence": { "sequence": "MGPHLLLLLLLGLAGQGSAGSLPELLQAPVGSSILVQCHYRPQDLRARKVWCRFLQGVCQPVVSSVVDRRTPAGSRIFLTDMGGGLLQVEMVTLQEEDAGEYGCLVEGASGPQTVHKVTLDVLPAAPGLEEEEETYQVGSLADSSSDPAGSASPLNPGLDKKSRLLIWGAVFLLGLLVVAVVLFTMMARRKGNRLGVCGQFQSSGISGLASSPGVHHSGDTGPAADLPSDIPYVRLDSPPSFDNTTYTNLPLDPLSEKPPSPSSFPPLPPKVMTSKPVTYATVVFPEGDKSGRASCEPVQDPPNSQTPPS", "length": 310, "header": "tr|A0A4X1SLK1-1|A0A4X1SLK1_PIG Isoform 1 of Triggering receptor expressed on myeloid cells like 1 OS=Sus scrofa OX=9823 GN=TREML1 PE=4 SV=1 CANONICAL=A0A4X1SLK1-1" }, "locus": { "chromosome": "7", "start_pos": 36460664, "end_pos": 36455877, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001793.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001793.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001747.2", "url": "https://www.ensembl.org/id/ENSSSCP00000001747.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLK1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-198933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-198933", "resource": "Reactome", "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZYT6-1", "protein_name": "Triggering receptor expressed on myeloid cells-like 1", "gene_name": "Treml1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCYLLLLLLGLAGQGSADSHPEVLQAAVGSSILVQCHYRLQDVRARKVWCRFVQEGCRPLVTSAVDRRAPESGRIFLTDMGGGLLQVEMVSLQEEDTGKYGCVVEGAAGPQTPHNISLLVLPPVPGPGDGEEAEEEEETYRTRAGSQLEDPSLDPSASAGPHEFRRRENSIPLIWGAALLLGLLVVAVVLFAVMARKKGNRLGVCGPSQNTGNSGMDPSSAAHHRSDSGLPSDIPHMRLDSPPSFDSIYTDPSLDPPSRKPPAPPPEPPLPPKVLTSSKPVTYATVVFPGRGKGEKASGEPAQDLPNRQTPPSK", "length": 315 }, "evidence": [ { "id": "A0A4X1SLK1", "url": "https://omabrowser.org/oma/group/A0A4X1SLK1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86YW5-1", "protein_name": "Trem-like transcript 1 protein", "gene_name": "TREML1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLTLLLLLLLGLEGQGIVGSLPEVLQAPVGSSILVQCHYRLQDVKAQKVWCRFLPEGCQPLVSSAVDRRAPAGRRTFLTDLGGGLLQVEMVTLQEEDAGEYGCMVDGARGPQILHRVSLNILPPEEEEETHKIGSLAENAFSDPAGSANPLEPSQDEKSIPLIWGAVLLVGLLVAAVVLFAVMAKRKQGNRLGVCGRFLSSRVSGMNPSSVVHHVSDSGPAAELPLDVPHIRLDSPPSFDNTTYTSLPLDSPSGKPSLPAPSSLPPLPPKVLVCSKPVTYATVIFPGGNKGGGTSCGPAQNPPNNQTPSS", "length": 311 }, "evidence": [ { "id": "A0A4X1SLK1", "url": "https://omabrowser.org/oma/group/A0A4X1SLK1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K558-1", "protein_name": "Trem-like transcript 1 protein", "gene_name": "Treml1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDCYLLLLLLLLGLAGQGSADSHPEVLQAPVGSSILVQCHYRLQDVRALKVWCQFLQEGCHPLVTSAVDRRAPGNGRIFLTDLGGGLLQVEMVTLQEEDTGEYGCVVEGAAGPQTLHRVSLLVLPPVPGPREGEEAEDEKETYRIGTGSLLEDPSLDPSASAGPHEFRRRENSIPLIWGAVLLLALVVVAVVIFAVMARKKGNRLVVCGPSQSTGVPGMDPPSAAHRSSDSGLPSDIPHVRLDSPPSFDSIYTGSSLDPPSSEPPAPPSQPPLPPKVLMSSKSVTYATVVFPGGDKGKIASCEPVQDPPNSQTPPSK", "length": 317 }, "evidence": [ { "id": "A0A4X1SLK1", "url": "https://omabrowser.org/oma/group/A0A4X1SLK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLK1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLK1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLK1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLK1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1" } ], "pmid": "" }, { "name": "platelet alpha granule", "id": "GO:0031091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031091", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLK1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLK1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1" } ], "pmid": "" }, { "name": "platelet activation", "id": "GO:0030168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030168", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SLK1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SLK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLK1" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 119, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 244, "end_pos": 246 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SM39-1", "uniprot_ac": "A0A4X1SM39", "uniprot_id": "A0A4X1SM39_PIG", "mass": { "chemical_mass": 23289.0, "monoisotopic_mass": 23289.0 }, "refseq": {}, "gene_names": [ { "name": "CRYBB2", "type": "recommended", "evidence": [ { "id": "A0A4X1SM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39" } ] } ], "protein_names": [ { "name": "Beta-crystallin B2", "type": "recommended", "evidence": [ { "id": "A0A4X1SM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39/entry#names_and_taxonomy" } ] }, { "name": "Beta-B2 crystallin", "type": "synonym", "evidence": [ { "id": "A0A4X1SM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39/entry#names_and_taxonomy" } ] }, { "name": "Beta-crystallin Bp", "type": "synonym", "evidence": [ { "id": "A0A4X1SM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Crystallins are the dominant structural components of the vertebrate eye lens.", "evidence": [ { "database": "UniProtKB", "id": "F1RG87", "url": "https://www.uniprot.org/uniprotkb/F1RG87#function" }, { "database": "UniProtKB", "id": "ARBA00003689", "url": "https://www.uniprot.org/uniprotkb/ARBA00003689#function" }, { "database": "UniProtKB", "id": "A0A4X1SM39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CRYBB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39", "locus": { "chromosome": "14", "start_pos": 43220837, "end_pos": 43209311, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009955", "url": "https://www.ensembl.org/id/ENSSSCG00000009955" } ] } } ], "crossref": [ { "id": "A0A4X1SM39", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SM39", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009955", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009955", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100736784", "url": "https://www.ncbi.nlm.nih.gov/gene/100736784", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100736784", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736784", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FRPIKQD", "url": "https://omabrowser.org/oma/group/FRPIKQD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RG87", "url": "https://www.orthodb.org/?gene=F1RG87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1SM39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SM39-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RG87", "url": "https://www.uniprot.org/uniprotkb/F1RG87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RG87-1", "url": "https://www.uniprot.org/uniprotkb/F1RG87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPPACRLHGHSQGLVSLIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEVIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSGDFGAPQPQVQSVRRIRDMQWHQRGAFHPSN", "length": 205, "header": "tr|A0A4X1SM39-1|A0A4X1SM39_PIG Isoform 1 of Beta-crystallin B2 OS=Sus scrofa OX=9823 GN=CRYBB2 PE=1 SV=1 CANONICAL=A0A4X1SM39-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SM39-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39/entry#A0A4X1SM39-1", "sequence": { "sequence": "MPPPACRLHGHSQGLVSLIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEVIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSGDFGAPQPQVQSVRRIRDMQWHQRGAFHPSN", "length": 205, "header": "tr|A0A4X1SM39-1|A0A4X1SM39_PIG Isoform 1 of Beta-crystallin B2 OS=Sus scrofa OX=9823 GN=CRYBB2 PE=1 SV=1 CANONICAL=A0A4X1SM39-1" }, "locus": { "chromosome": "14", "start_pos": 43220742, "end_pos": 43209409, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079137.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079137.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067246.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067246.2" } ] } }, { "isoform_ac": "F1RG87-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39/entry#F1RG87-1", "sequence": { "sequence": "MASDHQTQAGKPQPLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEVIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSGDFGAPQPQVQSVRRIRDMQWHQRGAFHPSN", "length": 205, "header": "tr|F1RG87-1|A0A4X1SM39_PIG Computationally mapped isoform of Beta-crystallin B2 OS=Sus scrofa OX=9823 GN=CRYBB2 PE=1 SV=1 CANONICAL=A0A4X1SM39-1" }, "locus": { "chromosome": "14", "start_pos": 43220742, "end_pos": 43211144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010910.4", "url": "https://www.ensembl.org/id/ENSSSCT00000010910.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010625.2", "url": "https://www.ensembl.org/id/ENSSSCP00000010625.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RG87", "url": "https://www.uniprot.org/uniprotkb/F1RG87" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100736784", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736784", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HME2-1", "protein_name": "Beta-crystallin B2", "gene_name": "Crybb2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASDHQTQAGKPQPLNPKIIIFEQENFQGHSHELSGPCPNLKETGMEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIVDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDNSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSS", "length": 205 }, "evidence": [ { "id": "A0A4X1SM39", "url": "https://omabrowser.org/oma/group/A0A4X1SM39/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P02522-1", "protein_name": "Beta-crystallin B2", "gene_name": "CRYBB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASDHQTQAGKPQPLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKITLYENPNFTGKKMEVIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSGDFGAPQPQVQSVRRIRDMQWHQRGAFHPSS", "length": 205 }, "evidence": [ { "id": "A0A4X1SM39", "url": "https://omabrowser.org/oma/group/A0A4X1SM39/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P43320-1", "protein_name": "Beta-crystallin B2", "gene_name": "CRYBB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN", "length": 205 }, "evidence": [ { "id": "A0A4X1SM39", "url": "https://omabrowser.org/oma/group/A0A4X1SM39/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62696-1", "protein_name": "Beta-crystallin B2", "gene_name": "Crybb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASDHQTQAGKPQPLNPKIIIFEQENFQGHSHELSGPCPNLKETGMEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIVDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDNSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSS", "length": 205 }, "evidence": [ { "id": "A0A4X1SM39", "url": "https://omabrowser.org/oma/group/A0A4X1SM39/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P62697-1", "protein_name": "Beta-crystallin B2", "gene_name": "Crybb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASDHQTQAGKPQPLNPKIIIFEQENFQGHSHELSGPCPNLKETGMEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIVDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDNSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSS", "length": 205 }, "evidence": [ { "id": "A0A4X1SM39", "url": "https://omabrowser.org/oma/group/A0A4X1SM39/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39" } ], "pmid": "" }, { "name": "lens development in camera-type eye", "id": "GO:0002088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002088", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of eye lens", "id": "GO:0005212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005212", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM39", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM39" }, { "id": "PS50915", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50915" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta/gamma crystallin 'Greek key'", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 56, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SM57-1", "uniprot_ac": "A0A4X1SM57", "uniprot_id": "A0A4X1SM57_PIG", "mass": { "chemical_mass": 19285.0, "monoisotopic_mass": 19285.0 }, "refseq": { "ac": "XP_020954325", "name": "translocator protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954325" }, "gene_names": [ { "name": "TSPO2", "type": "recommended", "evidence": [ { "id": "A0A4X1SM57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57" } ] }, { "name": "TSPO2", "type": "synonym", "evidence": [ { "id": "XP_020954325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954325" } ] } ], "protein_names": [ { "name": "Translocator protein", "type": "recommended", "evidence": [ { "id": "A0A4X1SM57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57/entry#names_and_taxonomy" } ] }, { "name": "Peripheral-type benzodiazepine receptor", "type": "synonym", "evidence": [ { "id": "A0A4X1SM57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57/entry#names_and_taxonomy" } ] }, { "name": "translocator protein 2", "type": "synonym", "evidence": [ { "id": "XP_020954325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954325" } ] } ], "function": [ { "annotation": "Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57#function" }, { "database": "UniProtKB", "id": "ARBA00058548", "url": "https://www.uniprot.org/uniprotkb/ARBA00058548#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TSPO2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57", "locus": { "chromosome": "7", "start_pos": 36353217, "end_pos": 36346486, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000038553", "url": "https://www.ensembl.org/id/ENSSSCG00000038553" } ] } } ], "crossref": [ { "id": "A0A4X1SM57", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SM57", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15904", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15904", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155551", "url": "https://www.ncbi.nlm.nih.gov/gene/100155551", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155551", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155551", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RDSLCPE", "url": "https://omabrowser.org/oma/group/RDSLCPE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SM57", "url": "https://www.orthodb.org/?gene=A0A4X1SM57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10057", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10057", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10057:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10057:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03073", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03073", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020954325", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954325", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SM57-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPQGVAFVALPLLGPTLVWLLTHRWMSGWCNNLRKPPWYPSHRALLLVWTAFYSLTGYASYLVWKELGGGLGWPLALPLGLYSVQLAVSWTVLILFFVAHSAGLALLHLLLLFGLVVSMALIWHPINKLAALLLLPYLAWLTVTTSITYRLWRDSLCPGHQPRLMGEKND", "length": 171, "header": "tr|A0A4X1SM57-1|A0A4X1SM57_PIG Isoform 1 of Translocator protein OS=Sus scrofa OX=9823 GN=TSPO2 PE=3 SV=1 CANONICAL=A0A4X1SM57-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SM57-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57/entry#A0A4X1SM57-1", "sequence": { "sequence": "MRPQGVAFVALPLLGPTLVWLLTHRWMSGWCNNLRKPPWYPSHRALLLVWTAFYSLTGYASYLVWKELGGGLGWPLALPLGLYSVQLAVSWTVLILFFVAHSAGLALLHLLLLFGLVVSMALIWHPINKLAALLLLPYLAWLTVTTSITYRLWRDSLCPGHQPRLMGEKND", "length": 171, "header": "tr|A0A4X1SM57-1|A0A4X1SM57_PIG Isoform 1 of Translocator protein OS=Sus scrofa OX=9823 GN=TSPO2 PE=3 SV=1 CANONICAL=A0A4X1SM57-1" }, "locus": { "chromosome": "7", "start_pos": 36352285, "end_pos": 36351187, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045945.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045945.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046818.1", "url": "https://www.ensembl.org/id/ENSSSCP00000046818.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155551", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155551", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IG90-1", "protein_name": "Translocator protein 2", "gene_name": "Tspo2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKLQGPVFVGVPLLGPILICMFTHNQTTSWCEDERKLWCPPHKVILLVWATIYSVIGYASYLVWKDLGGGFRWPLALPLGLYTLQLTLSWTFLMLFLTANNPGLALLDLLLLYGLVASMVLIWQPINKLAALLLLPYLAWLTVTTAITYRLWRDSLCPAYQP", "length": 162 }, "evidence": [ { "id": "A0A4X1SM57", "url": "https://omabrowser.org/oma/group/A0A4X1SM57/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0RA45-1", "protein_name": "Translocator protein 2", "gene_name": "Tspo2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQLQGPVFVGVPLLGPILIWMFTHQLSSRCEDEKKLPWCPPHKVILLVWATIYSVMGYASYLVWKDLGGGFRWSLALPLGLYSFQLALSWTFLMLFLVVDSPGLALLDLLLLYGLVASMVLIWQPINKLAALLLLPYLAWLTVTTAITYRLWRDSLCPSYQP", "length": 162 }, "evidence": [ { "id": "A0A4X1SM57", "url": "https://omabrowser.org/oma/group/A0A4X1SM57/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5TGU0-1", "protein_name": "Translocator protein 2", "gene_name": "TSPO2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLQGAIFVLLPHLGPILVWLFTRDHMSGWCEGPRMLSWCPFYKVLLLVQTAIYSVVGYASYLVWKDLGGGLGWPLALPLGLYAVQLTISWTVLVLFFTVHNPGLALLHLLLLYGLVVSTALIWHPINKLAALLLLPYLAWLTVTSALTYHLWRDSLCPVHQPQPTEKSD", "length": 170 }, "evidence": [ { "id": "A0A4X1SM57", "url": "https://omabrowser.org/oma/group/A0A4X1SM57/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CRZ8-1", "protein_name": "Translocator protein 2", "gene_name": "Tspo2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQLQGPVFVGVPLLGPILICMLIHQPSSRCEDERKLPWCPPHKVILLVWVTIYSVMGYASYLVWKELGGGFRWPLALPLGLYSFQLALSWTFLVLFLAADSPGLALLDLLLLYGLVASLVFIWQPINKLAALLLLPYLAWLTVTTAITYRLWRDSLCPTYQP", "length": 162 }, "evidence": [ { "id": "A0A4X1SM57", "url": "https://omabrowser.org/oma/group/A0A4X1SM57/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "enucleate erythrocyte differentiation", "id": "GO:0043353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043353", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57" } ], "pmid": "" }, { "name": "intracellular cholesterol transport", "id": "GO:0032367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032367", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57" } ], "pmid": "" }, { "name": "lipid droplet organization", "id": "GO:0034389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034389", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57" } ], "pmid": "" }, { "name": "5-aminolevulinic acid import across plasma membrane", "id": "GO:0140484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140484", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57" } ], "pmid": "" }, { "name": "5-aminolevulinic acid transmembrane transporter activity", "id": "GO:0140485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140485", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SM57", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SM57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SMG4-1", "uniprot_ac": "A0A4X1SMG4", "uniprot_id": "A0A4X1SMG4_PIG", "mass": { "chemical_mass": 28374.0, "monoisotopic_mass": 28374.0 }, "refseq": {}, "gene_names": [ { "name": "GZMA", "type": "recommended", "evidence": [ { "id": "A0A4X1SMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ] } ], "protein_names": [ { "name": "Granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)", "type": "synonym", "evidence": [ { "id": "A0A4X1SMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GZMA", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4", "locus": { "chromosome": "16", "start_pos": 34290477, "end_pos": 34282120, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016903", "url": "https://www.ensembl.org/id/ENSSSCG00000016903" } ] } } ], "crossref": [ { "id": "A0A4X1SMG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SMG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YPCYDPA", "url": "https://omabrowser.org/oma/group/YPCYDPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271:SF69", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271:SF69", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SMG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNSSTFLAATLSIVIFLQIHEDFCVEIIGGNPVTPHSRPYMVLLEGKNICAGALIAKDWVLTAAHCALNKKSQIILGAHSITKKEPEKQIMLVKKEYPYPCFDQDTHEGDLKLLKLNKKATLNKNVAVLHLPKVGDDVKPGTVCRVAGWGKFHNNSPRSDILREVNVTVIDRKICNDKSHYNYTTVIGLNMICAGSPQGGKDSCNGDSGAPLICEGIFRGVTAFGLSEKCGDPRGPGVYILLSKKHLNWIVNTMKHAV", "length": 259, "header": "tr|A0A4X1SMG4-1|A0A4X1SMG4_PIG Isoform 1 of Granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) OS=Sus scrofa OX=9823 GN=GZMA PE=1 SV=1 CANONICAL=A0A4X1SMG4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SMG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4/entry#A0A4X1SMG4-1", "sequence": { "sequence": "MRNSSTFLAATLSIVIFLQIHEDFCVEIIGGNPVTPHSRPYMVLLEGKNICAGALIAKDWVLTAAHCALNKKSQIILGAHSITKKEPEKQIMLVKKEYPYPCFDQDTHEGDLKLLKLNKKATLNKNVAVLHLPKVGDDVKPGTVCRVAGWGKFHNNSPRSDILREVNVTVIDRKICNDKSHYNYTTVIGLNMICAGSPQGGKDSCNGDSGAPLICEGIFRGVTAFGLSEKCGDPRGPGVYILLSKKHLNWIVNTMKHAV", "length": 259, "header": "tr|A0A4X1SMG4-1|A0A4X1SMG4_PIG Isoform 1 of Granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) OS=Sus scrofa OX=9823 GN=GZMA PE=1 SV=1 CANONICAL=A0A4X1SMG4-1" }, "locus": { "chromosome": "16", "start_pos": 34290404, "end_pos": 34282164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018409.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018409.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017912.2", "url": "https://www.ensembl.org/id/ENSSSCP00000017912.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "G3V7E3-1", "protein_name": "Granzyme A", "gene_name": "Gzma", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNPCAPWVSSLTTVIFLLLIPEGGCERIIGGDTVVPHSRPYMVLLKLKPDSVCAGALIAKNWVLTAAHCIPGKKSEVILGAHSIKKEPEQQILSVKKAYPYPCFDKHTHEGDLQLLRLKKKATLNKNVAILHLPKKGDDVKPGTRCHVAGWGRFHNKSPPSDTLREVNITVIDRKICNDEKHYNFNPVIGLNMICAGNLRGGKDSCYGDSGGPLLCEGIFRGITAFGLEGTCGDPKGPGIYTLLSDKHLDWIRKTAKGAV", "length": 261 }, "evidence": [ { "id": "A0A4X1SMG4", "url": "https://omabrowser.org/oma/group/A0A4X1SMG4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P11032-1", "protein_name": "Granzyme A", "gene_name": "Gzma", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRNASGPRGPSLATLLFLLLIPEGGCERIIGGDTVVPHSRPYMALLKLSSNTICAGALIEKNWVLTAAHCNVGKRSKFILGAHSINKEPEQQILTVKKAFPYPCYDEYTREGDLQLVRLKKKATVNRNVAILHLPKKGDDVKPGTRCRVAGWGRFGNKSAPSETLREVNITVIDRKICNDEKHYNFHPVIGLNMICAGDLRGGKDSCNGDSGSPLLCDGILRGITSFGGEKCGDRRWPGVYTFLSDKHLNWIKKIMKGSV", "length": 260 }, "evidence": [ { "id": "A0A4X1SMG4", "url": "https://omabrowser.org/oma/group/A0A4X1SMG4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P12544-1", "protein_name": "Granzyme A", "gene_name": "GZMA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV", "length": 262 }, "evidence": [ { "id": "A0A4X1SMG4", "url": "https://omabrowser.org/oma/group/A0A4X1SMG4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ], "pmid": "" }, { "name": "cytolytic granule", "id": "GO:0044194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044194", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ], "pmid": "" }, { "name": "granzyme-mediated programmed cell death signaling pathway", "id": "GO:0140507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140507", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ], "pmid": "" }, { "name": "cytotoxic T cell pyroptotic cell death", "id": "GO:1902483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902483", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMG4" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 256, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SMQ2-1", "uniprot_ac": "A0A4X1SMQ2", "uniprot_id": "A0A4X1SMQ2_PIG", "mass": { "chemical_mass": 17353.0, "monoisotopic_mass": 17353.0 }, "refseq": {}, "gene_names": [ { "name": "NCBP2L", "type": "recommended", "evidence": [ { "id": "A0A4X1SMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2" } ] } ], "protein_names": [ { "name": "Nuclear cap-binding protein subunit 2", "type": "recommended", "evidence": [ { "id": "A0A4X1SMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2/entry#names_and_taxonomy" } ] }, { "name": "20 kDa nuclear cap-binding protein", "type": "synonym", "evidence": [ { "id": "A0A4X1SMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2#function" }, { "database": "UniProtKB", "id": "RU364036", "url": "https://www.uniprot.org/uniprotkb/RU364036#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NCBP2L", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2", "locus": { "chromosome": "X", "start_pos": 88259035, "end_pos": 88258577, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012562", "url": "https://www.ensembl.org/id/ENSSSCG00000012562" } ] } } ], "crossref": [ { "id": "A0A4X1SMQ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SMQ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12240", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12240", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LDEWIIR", "url": "https://omabrowser.org/oma/group/LDEWIIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR18847", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18847", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18847:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18847:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1SMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SMQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNDLTIQRSNSCPELSEYQDQQFRGDNEEHEKLLMESSTLYVENLSIYTTEEQIFELFSRCGDVKNVFMGLDNIKKTACGFCFVEYHLRADAENAMRFLNGTLLDDRIIHTKWDIGFKEGRQYAHGRCGGQVRDEFREDANVGGGGFGSQA", "length": 152, "header": "tr|A0A4X1SMQ2-1|A0A4X1SMQ2_PIG Isoform 1 of Nuclear cap-binding protein subunit 2 OS=Sus scrofa OX=9823 GN=NCBP2L PE=3 SV=1 CANONICAL=A0A4X1SMQ2-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SMQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2/entry#A0A4X1SMQ2-1", "sequence": { "sequence": "MSNDLTIQRSNSCPELSEYQDQQFRGDNEEHEKLLMESSTLYVENLSIYTTEEQIFELFSRCGDVKNVFMGLDNIKKTACGFCFVEYHLRADAENAMRFLNGTLLDDRIIHTKWDIGFKEGRQYAHGRCGGQVRDEFREDANVGGGGFGSQA", "length": 152, "header": "tr|A0A4X1SMQ2-1|A0A4X1SMQ2_PIG Isoform 1 of Nuclear cap-binding protein subunit 2 OS=Sus scrofa OX=9823 GN=NCBP2L PE=3 SV=1 CANONICAL=A0A4X1SMQ2-1" }, "locus": { "chromosome": "X", "start_pos": 88259032, "end_pos": 88258577, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013736.2", "url": "https://www.ensembl.org/id/ENSSSCT00000013736.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013358.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013358.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2" } ], "pmid": "" }, { "name": "nuclear cap binding complex", "id": "GO:0005846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005846", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2" } ], "pmid": "" }, { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA cap binding", "id": "GO:0000339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000339", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMQ2" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 117, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SN09-1", "uniprot_ac": "A0A4X1SN09", "uniprot_id": "A0A4X1SN09_PIG", "mass": { "chemical_mass": 56578.0, "monoisotopic_mass": 56578.0 }, "refseq": {}, "gene_names": [ { "name": "CYP2G2", "type": "recommended", "evidence": [ { "id": "A0A4X1SN09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09" } ] } ], "protein_names": [ { "name": "Cytochrome P450", "type": "recommended", "evidence": [ { "id": "A0A4X1SN09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09/entry#names_and_taxonomy" } ] }, { "name": "1.14.14.1", "type": "synonym", "evidence": [ { "id": "A0A4X1SN09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cytochromes P450 are a group of heme-thiolate monooxygenases.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SN09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09#function" }, { "database": "UniProtKB", "id": "RU368053", "url": "https://www.uniprot.org/uniprotkb/RU368053#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SN09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CYP2G2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09", "locus": {} } ], "crossref": [ { "id": "A0A4X1SN09", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SN09", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20670", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20670", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPPTYKL", "url": "https://omabrowser.org/oma/group/IPPTYKL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SN09", "url": "https://www.orthodb.org/?gene=A0A4X1SN09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300:SF424", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300:SF424", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17149", "url": "https://www.rhea-db.org/rhea/17149", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SN09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SN09-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELGGAFTIFLALCLSCLLILIAWKRISKGGKLPPGPTPIPFLGNLLQVRTDATFQSFMKLREKYGPVFTVYMGPRPVVVLCGHEAVKEALIDRADEFSGRGELASVERNFQGHGVALANGDRWRILRRFSLTILRDFGMGKRSIEERIQEEAGFLLQELRKTKGAPIEPTFFLSRTVSNVISSVVFGSRFDYEDKQFLKLLQMINQSFIEMSTPWAQLYDMYSGIMQYLPGRHNRIYYLIEELKDFIASRVKINEASLDPQNPRDFIDCFLIKMHQDKDNPHTEFNLKNLVLTTLNLFFAGTETVSSTLRYGLLLMMKHPEVEAKIHEEIDQVIGPHRIPRVDDRVKMPYTDAVIHEIQRLTDIVPMGVPHNVIRDTHFRGYLLPKGTDVFPLLGSVLKDPKYFRYPDAFYPQHFLDEQGRFKKNEAFVPFSSGKRICLGEAMARMELFLYFTSILQNFTLRSLVPPAHIDITPQVSGFGNIPPTYELCLIAR", "length": 494, "header": "tr|A0A4X1SN09-1|A0A4X1SN09_PIG Isoform 1 of Cytochrome P450 OS=Sus scrofa OX=9823 GN=CYP2G2 PE=3 SV=1 CANONICAL=A0A4X1SN09-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SN09-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09/entry#A0A4X1SN09-1", "sequence": { "sequence": "MELGGAFTIFLALCLSCLLILIAWKRISKGGKLPPGPTPIPFLGNLLQVRTDATFQSFMKLREKYGPVFTVYMGPRPVVVLCGHEAVKEALIDRADEFSGRGELASVERNFQGHGVALANGDRWRILRRFSLTILRDFGMGKRSIEERIQEEAGFLLQELRKTKGAPIEPTFFLSRTVSNVISSVVFGSRFDYEDKQFLKLLQMINQSFIEMSTPWAQLYDMYSGIMQYLPGRHNRIYYLIEELKDFIASRVKINEASLDPQNPRDFIDCFLIKMHQDKDNPHTEFNLKNLVLTTLNLFFAGTETVSSTLRYGLLLMMKHPEVEAKIHEEIDQVIGPHRIPRVDDRVKMPYTDAVIHEIQRLTDIVPMGVPHNVIRDTHFRGYLLPKGTDVFPLLGSVLKDPKYFRYPDAFYPQHFLDEQGRFKKNEAFVPFSSGKRICLGEAMARMELFLYFTSILQNFTLRSLVPPAHIDITPQVSGFGNIPPTYELCLIAR", "length": 494, "header": "tr|A0A4X1SN09-1|A0A4X1SN09_PIG Isoform 1 of Cytochrome P450 OS=Sus scrofa OX=9823 GN=CYP2G2 PE=3 SV=1 CANONICAL=A0A4X1SN09-1" }, "locus": { "chromosome": "6", "start_pos": 49083476, "end_pos": 49070656, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025438.3", "url": "https://www.ensembl.org/id/ENSSSCT00000025438.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019606.2", "url": "https://www.ensembl.org/id/ENSSSCP00000019606.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 38, "start_aa": "Thr", "end_pos": 38, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr38", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SN09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1B8U6-1", "protein_name": "Cytochrome P450", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELGGAFTIFLALCLSCLLILIAWKRMSKGGKLPPGPTPIPFLGNVLQVRTDATFQSFMKLKEKYGPVFTVYMGPRPVVVLCGHEAVKEALVDRADEFSGRGELASVERNFQGHGVALANGERWRILRRFSLTILRDFGMGKRSIEERIQEEAGFLLVELRKTRGARIEPTFFLSRTVSNVISSVVFGSRFDYEDQQFLKLLQMINQSFIEMSTSWAQLYDMYSGIMQYLPGRHNRIYYLIEELKDFIASKVKINEASLDPQNPRDFIDCFLIKMHQDKNNPHTEFNLKNLVLTTLNLFFAGTETVSSTLRYGLLLMMKHPEVEAKIHEEIDQVIGPHRIPSVDDRAKMPYTDAVIHEIQRLTDIVPMGVPHNVIRDTHFRGYLLPKGTDVFPLLGSVLKDPKYFRYPDAFYPQHFLDEQGHFKKNEAFVPFSSGKRICLGEAMARMELFLYFTSILQNFSLRSLVPPADIDITPKVSGFGNIPPTYELCFMVR", "length": 494 }, "evidence": [ { "id": "A0A4X1SN09", "url": "https://omabrowser.org/oma/group/A0A4X1SN09/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P10610-1", "protein_name": "Cytochrome P450 2G1", "gene_name": "Cyp2g1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALGGAFSIFMTLCLSCLLILIAWKRTSRGGKLPPGPTPIPFLGNLLQVRIDATFQSFLKLQKKYGSVFTVYFGPRPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYGLALSNGERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEELHKVKGAPIDPTFYLSRTVSNVICSVVFGKRFDYEDQRFRSLMKMINESFVEMSMPWAQLYDMYWGVIQYFPGRHNRLYNLIEELKDFIASRVKINEASFDPSNPRDFIDCFLIKMYQDKSDPHSEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLMKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVIRDTHFRGYFLPKGTDVYPLIGSVLKDPKYFRYPEAFYPQHFLDEQGRFKKNDAFVAFSSGKRICVGEALARMELFLYFTSILQRFSLRSLVPPADIDIAHKISGFGNIPPTYELCFMAR", "length": 494 }, "evidence": [ { "id": "A0A4X1SN09", "url": "https://omabrowser.org/oma/group/A0A4X1SN09/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SN09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SN09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SN09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09" } ], "pmid": "" }, { "name": "arachidonate epoxygenase activity", "id": "GO:0008392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008392", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SN09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SN09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SN09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SN09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09" } ], "pmid": "" }, { "name": "epoxygenase P450 pathway", "id": "GO:0019373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019373", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SN09", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17149", "name": "", "equation": "an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17149", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17149" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 38 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 459, "end_pos": 461 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SPI6-1", "uniprot_ac": "A0A4X1SPI6", "uniprot_id": "A0A4X1SPI6_PIG", "mass": { "chemical_mass": 45144.0, "monoisotopic_mass": 45144.0 }, "refseq": { "ac": "XP_003134407", "name": "casein kinase II subunit alpha", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134407" }, "gene_names": [ { "name": "CSNK2A1", "type": "recommended", "evidence": [ { "id": "A0A4X1SPI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ] }, { "name": "CSNK2A1", "type": "synonym", "evidence": [ { "id": "XP_003134407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134407" } ] } ], "protein_names": [ { "name": "Casein kinase II subunit alpha", "type": "recommended", "evidence": [ { "id": "A0A4X1SPI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A4X1SPI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#names_and_taxonomy" } ] }, { "name": "CK II alpha", "type": "synonym", "evidence": [ { "id": "A0A4X1SPI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#names_and_taxonomy" } ] }, { "name": "casein kinase II subunit alpha", "type": "synonym", "evidence": [ { "id": "XP_003134407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134407" } ] } ], "function": [ { "annotation": "Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SN68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN68#function" }, { "database": "UniProtKB", "id": "RU369118", "url": "https://www.uniprot.org/uniprotkb/RU369118#function" }, { "database": "UniProtKB", "id": "A0A4X1SN72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN72#function" }, { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6#function" }, { "database": "UniProtKB", "id": "A0A5G2QPT4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT4#function" }, { "database": "UniProtKB", "id": "A0A5G2R4G4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4G4#function" }, { "database": "UniProtKB", "id": "A0A5G2RLX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLX3#function" }, { "database": "UniProtKB", "id": "A0A5G2QHC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHC2#function" }, { "database": "UniProtKB", "id": "A0A5G2QMN7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMN7#function" }, { "database": "UniProtKB", "id": "A0A8W4FLS5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLS5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CSNK2A1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000007203", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007203", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14132", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14132", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100517435", "url": "https://www.ncbi.nlm.nih.gov/gene/100517435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517435", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517435", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ECHMIEW", "url": "https://omabrowser.org/oma/group/ECHMIEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SPI6", "url": "https://www.orthodb.org/?gene=A0A4X1SPI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24054", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24054", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24054:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24054:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1483191", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483191", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-201688", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201688", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2514853", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2514853", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6804756", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804756", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6814122", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6814122", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8934903", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8934903", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939243", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8948751", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8948751", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9768727", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9768727", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9929491", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9929491", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003134407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134407", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SN68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SN68-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SN72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SN72-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SN72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SPI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SPM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SPM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHC2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMN7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPT4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4G4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4G4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLX3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLS5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ", "length": 391, "header": "tr|A0A4X1SPI6-1|A0A4X1SPI6_PIG Isoform 1 of Casein kinase II subunit alpha OS=Sus scrofa OX=9823 GN=CSNK2A1 PE=1 SV=1 CANONICAL=A0A4X1SPI6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SN68-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#A0A4X1SN68-1", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ", "length": 374, "header": "tr|A0A4X1SN68-1|A0A4X1SPI6_PIG Computationally mapped isoform of Casein kinase II subunit alpha OS=Sus scrofa OX=9823 GN=CSNK2A1 PE=1 SV=1 CANONICAL=A0A4X1SPI6-1" }, "locus": { "chromosome": "17", "start_pos": 34745236, "end_pos": 34722124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049766.2", "url": "https://www.ensembl.org/id/ENSSSCT00000049766.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052665.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052665.2" } ] } }, { "isoform_ac": "A0A4X1SN72-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#A0A4X1SN72-1", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ", "length": 354, "header": "tr|A0A4X1SN72-1|A0A4X1SN72_PIG Computationally mapped isoform of Casein kinase II subunit alpha OS=Sus scrofa OX=9823 GN=CSNK2A1 PE=1 SV=1 CANONICAL=A0A4X1SPI6-1" }, "locus": { "chromosome": "17", "start_pos": 34745236, "end_pos": 34722124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072590.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072590.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070288.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070288.1" } ] } }, { "isoform_ac": "A0A4X1SPI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#A0A4X1SPI6-1", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ", "length": 391, "header": "tr|A0A4X1SPI6-1|A0A4X1SPI6_PIG Isoform 1 of Casein kinase II subunit alpha OS=Sus scrofa OX=9823 GN=CSNK2A1 PE=1 SV=1 CANONICAL=A0A4X1SPI6-1" }, "locus": { "chromosome": "17", "start_pos": 34745236, "end_pos": 34722124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059848.2", "url": "https://www.ensembl.org/id/ENSSSCT00000059848.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042463.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042463.1" } ] } }, { "isoform_ac": "A0A4X1SPM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#A0A4X1SPM6-1", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ", "length": 363, "header": "tr|A0A4X1SPM6-1|A0A4X1SPM6_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=CSNK2A1 PE=1 SV=1 CANONICAL=A0A4X1SPI6-1" }, "locus": { "chromosome": "17", "start_pos": 34745236, "end_pos": 34722124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080074.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080074.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065830.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065830.1" } ] } }, { "isoform_ac": "A0A5G2QHC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#A0A5G2QHC2-1", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFCELKLFSPQTLCVSGALQNRTGIPTFLT", "length": 301, "header": "tr|A0A5G2QHC2-1|A0A5G2QHC2_PIG Computationally mapped isoform of Casein kinase II subunit alpha OS=Sus scrofa OX=9823 GN=CSNK2A1 PE=1 SV=2 CANONICAL=A0A4X1SPI6-1" }, "locus": { "chromosome": "17", "start_pos": 34742070, "end_pos": 34722124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070599.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070599.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064188.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064188.2" } ] } }, { "isoform_ac": "A0A5G2QMN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#A0A5G2QMN7-1", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVVSIQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFCELKLFSPQTLSG", "length": 323, "header": "tr|A0A5G2QMN7-1|A0A5G2QMN7_PIG Computationally mapped isoform of Casein kinase II subunit alpha OS=Sus scrofa OX=9823 GN=CSNK2A1 PE=1 SV=1 CANONICAL=A0A4X1SPI6-1" }, "locus": { "chromosome": "17", "start_pos": 34742667, "end_pos": 34722124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074699.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074699.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063383.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063383.1" } ] } }, { "isoform_ac": "A0A5G2QPT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#A0A5G2QPT4-1", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ", "length": 354, "header": "tr|A0A5G2QPT4-1|A0A4X1SPI6_PIG Computationally mapped isoform of Casein kinase II subunit alpha OS=Sus scrofa OX=9823 GN=CSNK2A1 PE=1 SV=1 CANONICAL=A0A4X1SPI6-1" }, "locus": { "chromosome": "17", "start_pos": 34745236, "end_pos": 34722124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069866.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069866.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066725.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066725.1" } ] } }, { "isoform_ac": "A0A5G2R4G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#A0A5G2R4G4-1", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGQFVGKFIFQKEKSIIILTLAPSSLIITLLTTDLRSSPHQVSGCF", "length": 398, "header": "tr|A0A5G2R4G4-1|A0A4X1SPI6_PIG Computationally mapped isoform of Casein kinase II subunit alpha OS=Sus scrofa OX=9823 GN=CSNK2A1 PE=1 SV=1 CANONICAL=A0A4X1SPI6-1" }, "locus": { "chromosome": "17", "start_pos": 34743202, "end_pos": 34722124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087402.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087402.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065452.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065452.1" } ] } }, { "isoform_ac": "A0A5G2RLX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#A0A5G2RLX3-1", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFCELKLFSPQTLCVSGALQNRTGIPTFLT", "length": 318, "header": "tr|A0A5G2RLX3-1|A0A5G2RLX3_PIG Computationally mapped isoform of Casein kinase II subunit alpha OS=Sus scrofa OX=9823 GN=CSNK2A1 PE=1 SV=2 CANONICAL=A0A4X1SPI6-1" }, "locus": { "chromosome": "17", "start_pos": 34742070, "end_pos": 34722124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070026.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070026.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073434.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073434.2" } ] } }, { "isoform_ac": "A0A8W4FLS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6/entry#A0A8W4FLS5-1", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVVSIQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFCELKLFSPQTLCVSGALQNRTGIPTFLT", "length": 338, "header": "tr|A0A8W4FLS5-1|A0A4X1SPI6_PIG Computationally mapped isoform of Casein kinase II subunit alpha OS=Sus scrofa OX=9823 GN=CSNK2A1 PE=1 SV=1 CANONICAL=A0A4X1SPI6-1" }, "locus": { "chromosome": "17", "start_pos": 34742070, "end_pos": 34722124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092564.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092564.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079848.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079848.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 360, "start_aa": "Thr", "end_pos": 360, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr360", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FLS5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLS5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517435", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517435", "resource": "KEGG Pathway" }, { "id": "R-SSC-1483191", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483191", "resource": "Reactome", "description": "Synthesis of PC" }, { "id": "R-SSC-201688", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201688", "resource": "Reactome", "description": "WNT mediated activation of DVL" }, { "id": "R-SSC-2514853", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2514853", "resource": "Reactome", "description": "Condensation of Prometaphase Chromosomes" }, { "id": "R-SSC-6804756", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804756", "resource": "Reactome", "description": "Regulation of TP53 Activity through Phosphorylation" }, { "id": "R-SSC-6814122", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6814122", "resource": "Reactome", "description": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" }, { "id": "R-SSC-8934903", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8934903", "resource": "Reactome", "description": "Receptor Mediated Mitophagy" }, { "id": "R-SSC-8939243", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" }, { "id": "R-SSC-8948751", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8948751", "resource": "Reactome", "description": "Regulation of PTEN stability and activity" }, { "id": "R-SSC-9768727", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9768727", "resource": "Reactome", "description": "Regulation of CDH1 posttranslational processing and trafficking to plasma membrane" }, { "id": "R-SSC-9929491", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9929491", "resource": "Reactome", "description": "SPOP-mediated proteasomal degradation of PD-L1(CD274)" } ], "orthologs": [ { "uniprot_canonical_ac": "P08181-1", "protein_name": "Casein kinase II subunit alpha", "gene_name": "CkIIalpha", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTLPSAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYFLPIVNGQMNPNNQQ", "length": 336 }, "evidence": [ { "id": "A0A4X1SPI6", "url": "https://omabrowser.org/oma/group/A0A4X1SPI6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P15790-1", "protein_name": "Casein kinase II subunit alpha", "gene_name": "CKA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIEK", "length": 372 }, "evidence": [ { "id": "A0A4X1SPI6", "url": "https://omabrowser.org/oma/group/A0A4X1SPI6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P19139-1", "protein_name": "Casein kinase II subunit alpha", "gene_name": "Csnk2a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMSSAGMAGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANSLGIPVPAAAGAQQ", "length": 391 }, "evidence": [ { "id": "A0A4X1SPI6", "url": "https://omabrowser.org/oma/group/A0A4X1SPI6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21868-1", "protein_name": "Casein kinase II subunit alpha", "gene_name": "CSNK2A1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYPIVKDQARMGSSNMPGGSTPVSSASMMSGISSVPTPSPLGPLAGSPVISATTTLGMPVPAAAGAQQ", "length": 391 }, "evidence": [ { "id": "A0A4X1SPI6", "url": "https://omabrowser.org/oma/group/A0A4X1SPI6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P68399-1", "protein_name": "Casein kinase II subunit alpha", "gene_name": "CSNK2A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ", "length": 391 }, "evidence": [ { "id": "A0A4X1SPI6", "url": "https://omabrowser.org/oma/group/A0A4X1SPI6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P68400-1", "protein_name": "Casein kinase II subunit alpha", "gene_name": "CSNK2A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ", "length": 391 }, "evidence": [ { "id": "A0A4X1SPI6", "url": "https://omabrowser.org/oma/group/A0A4X1SPI6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q02720-1", "protein_name": "Casein kinase II subunit alpha", "gene_name": "casK", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNHSSKKNKNRILRNKARIYCDVNLHKPKEYWNYEALNVKWETQDDYEIIRKIGRGKYSEVFEGANIKNNEKCVIKVLKPVKKKKIKREIKILQNLCGGPNIITLYDVVRDPQSKTPSLIFEYINNTDFKHLSPTLTDFDVRYYIRELLHALDFCHSNGIMHRDVKPSNVMIDHQKRKLYLIDWGLAEFYHPNQDYNVRVASRPYKGPELLVDMEDYDYSLDMWSLGCMFAGMLFQKDPFFHGHDNIDQLVKIVKILGTEEFYAYLDKYGIVVDHTILSIIGKHPKKPWSRFITKENQHLAVPEAIDFLEKLLRYDPAERLTTREAMEHPYFKPLSH", "length": 337 }, "evidence": [ { "id": "A0A4X1SPI6", "url": "https://omabrowser.org/oma/group/A0A4X1SPI6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q08466-1", "protein_name": "Casein kinase II subunit alpha-2", "gene_name": "CKA2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MHLIFFFSYFLRRYLLLLCAILILRAPLAHSLIPPLTCVNTGTVESDVTGIRFDRCLDTDSLAKISLSTVMSKARVYTDVNVIRPKDYWDYESLNVQWGEQDDYEVVRKVGRGKYSEVFEGINMNNNEKCIIKILKPVKKKKIRREIKILQNLCGGPNIVKLLDVVRDQHSKTPSLIFEYVNSTDFKVLYPTLTDYDIRYYIYELLKALDFCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGTDELNAYLNKYQLELDTQLEALVGRHSRKPWSKFINADNRHLVSPEAIDYLDKLLRYDHQDRLTAKEAMAHPYFAQVRAAESSRMRTQ", "length": 403 }, "evidence": [ { "id": "A0A4X1SPI6", "url": "https://omabrowser.org/oma/group/A0A4X1SPI6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q60737-1", "protein_name": "Casein kinase II subunit alpha", "gene_name": "Csnk2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMSSTSMAGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANSLGIPVPAAAGAQQ", "length": 391 }, "evidence": [ { "id": "A0A4X1SPI6", "url": "https://omabrowser.org/oma/group/A0A4X1SPI6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ], "pmid": "" }, { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ], "pmid": "" }, { "name": "protein kinase CK2 complex", "id": "GO:0005956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005956", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SPI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-SSC-201717", "name": "CSNK2-mediated phosphorylation of DVL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-201717", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201717" } ] }, { "id": "R-SSC-2529020", "name": "CK2 phosphorylates condensin I subunits", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2529020", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2529020" } ] }, { "id": "R-SSC-6805059", "name": "CK2:FACT phosphorylates TP53", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6805059", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6805059" } ] }, { "id": "R-SSC-6805061", "name": "CK2 binds FACT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6805061", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6805061" } ] }, { "id": "R-SSC-6814409", "name": "CK2 phosphorylates PDCL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-SSC-6813727" ], "output_participant_list": [ "R-SSC-6814228" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6814409", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6814409" } ] }, { "id": "R-SSC-8850945", "name": "Casein kinase II phosphorylates PTEN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-SSC-199420" ], "output_participant_list": [ "R-SSC-8850936" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8850945", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8850945" } ] }, { "id": "R-SSC-8873929", "name": "Casein kinase II phosphorylates STARD10", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-SSC-8873867" ], "output_participant_list": [ "R-SSC-8873930" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8873929", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8873929" } ] }, { "id": "R-SSC-8937989", "name": "RUNX1 binds PRC1 complexes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8937989", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8937989" } ] }, { "id": "R-SSC-8948039", "name": "FUNDC1 is phosphorylated by CK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-SSC-8934922" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8948039", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8948039" } ] }, { "id": "R-SSC-9931418", "name": "CK2 phosphorylates CD274", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-SSC-9930703" ], "output_participant_list": [ "R-SSC-9931388" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9931418", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9931418" } ] }, { "id": "R-SSC-9933380", "name": "Cytosolic tail of CDH1 is phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-SSC-9933097" ], "output_participant_list": [ "R-SSC-9933653" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9933380", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9933380" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-199420", "participant_name": "PTEN [cytosol]", "crossref": [ { "id": "ENSSSCG00000010440", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000011128", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000011425", "database": "ENSEMBL", "url": "" }, { "id": "F2Z5H1", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-6813727", "participant_name": "PDCL [cytosol]", "crossref": [ { "id": "A0A286ZXX5", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000038554", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000035388", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000066119", "database": "ENSEMBL", "url": "" }, { "id": "XP_001927731.1", "database": "RefSeq", "url": "" }, { "id": "91245", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-6814228", "participant_name": "phospho-PDCL [cytosol]", "crossref": [ { "id": "ENSSSCT00000066119", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000038554", "database": "ENSEMBL", "url": "" }, { "id": "91245", "database": "VGNC", "url": "" }, { "id": "A0A286ZXX5", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000035388", "database": "ENSEMBL", "url": "" }, { "id": "XP_001927731.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-8850936", "participant_name": "phospho-PTEN [cytosol]", "crossref": [ { "id": "ENSSSCT00000011425", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000010440", "database": "ENSEMBL", "url": "" }, { "id": "F2Z5H1", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000011128", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-8873867", "participant_name": "STARD10 [cytosol]", "crossref": [ { "id": "A0A287A5S1", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000014818", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000039211", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000064557", "database": "ENSEMBL", "url": "" }, { "id": "93530", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-8873930", "participant_name": "phospho-STARD10 [cytosol]", "crossref": [ { "id": "ENSSSCT00000064557", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000014818", "database": "ENSEMBL", "url": "" }, { "id": "A0A287A5S1", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000039211", "database": "ENSEMBL", "url": "" }, { "id": "93530", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-8934922", "participant_name": "FUNDC1 [mitochondrial outer membrane]", "crossref": [ { "id": "F1RWZ9", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000012258", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000013045", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000013405", "database": "ENSEMBL", "url": "" }, { "id": "XP_003135086.1", "database": "RefSeq", "url": "" }, { "id": "88264", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9930703", "participant_name": "CD274 [endoplasmic reticulum membrane]", "crossref": [ { "id": "A0A8D2BPF9", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000005211", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000034275", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000058965", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9931388", "participant_name": "phospho-CD274 [endoplasmic reticulum membrane]", "crossref": [ { "id": "ENSSSCG00000005211", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000058965", "database": "ENSEMBL", "url": "" }, { "id": "A0A8D2BPF9", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000034275", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9933097", "participant_name": "Man,Man9GlucNAc2-CDH1(23-882) [endoplasmic reticulum membrane]", "crossref": [ { "id": "I3L5Z1", "database": "UniProt", "url": "" }, { "id": "86473", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9933653", "participant_name": "phospho-Man,Man9GlucNAc2,p-3S-CDH1(23-882) [endoplasmic reticulum membrane]", "crossref": [ { "id": "86473", "database": "VGNC", "url": "" }, { "id": "I3L5Z1", "database": "UniProt", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SPI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPI6" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 324, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 360 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 58, "end_pos": 60 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SNE9-1", "uniprot_ac": "A0A4X1SNE9", "uniprot_id": "A0A4X1SNE9_PIG", "mass": { "chemical_mass": 35189.0, "monoisotopic_mass": 35189.0 }, "refseq": { "ac": "XP_020946890", "name": "olfactory receptor 6C2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946890" }, "gene_names": [ { "name": "LOC110260575", "type": "recommended", "evidence": [ { "id": "A0A4X1SNE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9" } ] }, { "name": "LOC110260575", "type": "synonym", "evidence": [ { "id": "XP_020946890", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946890" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1SNE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6C2-like", "type": "synonym", "evidence": [ { "id": "XP_020946890", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946890" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNE9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNE9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110260575", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9", "locus": {} } ], "crossref": [ { "id": "A0A4X1SNE9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SNE9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110260575", "url": "https://www.ncbi.nlm.nih.gov/gene/110260575", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110260575", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110260575", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VTYNPCA", "url": "https://omabrowser.org/oma/group/VTYNPCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SNE9", "url": "https://www.orthodb.org/?gene=A0A4X1SNE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020946890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946890", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SNE9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SNE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNYTVLTTFILVGLTDDPDLQILLFIFLLLTYLLSVIGNLTIITLTFVDSRLKTPMYFFLRNFSFLEVSFTTVCIPRYLYTLATGDNTVTYNPCATQLFFVIVLGVTEFFLLTAMSYDRYVAICKPLHYTTIMSSTVCIRFLLGCYVIALIIVLPPYVMGLDLEFCDSNVIDHFGCDAAPILKITCSDTAFIERFVLVLAVLTLLFTLVCVILSYTYIIRTILRFPSAQQRKKAFSTCSSHVIVVSITYGSCIFIYIKPHAKEGVAMNKMVSVLTTSVAPVMNPFIYTLRNKQVVQAFKDMIKRVAAISKN", "length": 312, "header": "tr|A0A4X1SNE9-1|A0A4X1SNE9_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110260575 PE=3 SV=1 CANONICAL=A0A4X1SNE9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SNE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9/entry#A0A4X1SNE9-1", "sequence": { "sequence": "MTNYTVLTTFILVGLTDDPDLQILLFIFLLLTYLLSVIGNLTIITLTFVDSRLKTPMYFFLRNFSFLEVSFTTVCIPRYLYTLATGDNTVTYNPCATQLFFVIVLGVTEFFLLTAMSYDRYVAICKPLHYTTIMSSTVCIRFLLGCYVIALIIVLPPYVMGLDLEFCDSNVIDHFGCDAAPILKITCSDTAFIERFVLVLAVLTLLFTLVCVILSYTYIIRTILRFPSAQQRKKAFSTCSSHVIVVSITYGSCIFIYIKPHAKEGVAMNKMVSVLTTSVAPVMNPFIYTLRNKQVVQAFKDMIKRVAAISKN", "length": 312, "header": "tr|A0A4X1SNE9-1|A0A4X1SNE9_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110260575 PE=3 SV=1 CANONICAL=A0A4X1SNE9-1" }, "locus": { "chromosome": "5", "start_pos": 21012825, "end_pos": 21011890, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000360.2", "url": "https://www.ensembl.org/id/ENSSSCT00000000360.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000354.2", "url": "https://www.ensembl.org/id/ENSSSCP00000000354.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNE9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110260575", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110260575", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNE9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNE9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SNE9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SNE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SNE9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SP11-1", "uniprot_ac": "A0A4X1SP11", "uniprot_id": "A0A4X1SP11_PIG", "mass": { "chemical_mass": 69005.0, "monoisotopic_mass": 69005.0 }, "refseq": { "ac": "XP_013833642", "name": "transmembrane 9 superfamily member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013833642" }, "gene_names": [ { "name": "IPO4", "type": "recommended", "evidence": [ { "id": "A0A4X1SP11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11" } ] }, { "name": "TM9SF1", "type": "recommended", "evidence": [ { "id": "A0A4X1SP11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11" } ] }, { "name": "TM9SF1", "type": "synonym", "evidence": [ { "id": "XP_013833642", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013833642" }, { "id": "A0A4X1SP11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11" } ] } ], "protein_names": [ { "name": "Transmembrane 9 superfamily member", "type": "recommended", "evidence": [ { "id": "A0A4X1SP11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11/entry#names_and_taxonomy" } ] }, { "name": "transmembrane 9 superfamily member 1", "type": "synonym", "evidence": [ { "id": "XP_013833642", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013833642" } ] } ], "function": [ { "annotation": "Plays an essential role in autophagy.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FAU1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAU1#function" }, { "database": "UniProtKB", "id": "ARBA00037688", "url": "https://www.uniprot.org/uniprotkb/ARBA00037688#function" }, { "database": "UniProtKB", "id": "A0A4X1SP11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11#function" }, { "database": "UniProtKB", "id": "F1SGN5", "url": "https://www.uniprot.org/uniprotkb/F1SGN5#function" }, { "database": "UniProtKB", "id": "F1SGN4", "url": "https://www.uniprot.org/uniprotkb/F1SGN4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TM9SF1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11", "locus": { "chromosome": "7", "start_pos": 75110446, "end_pos": 75100273, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000054655", "url": "https://www.ensembl.org/id/ENSSSCG00000054655" } ] } } ], "crossref": [ { "id": "A0A4X1SP11", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SP11", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002000", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002000", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100520918", "url": "https://www.ncbi.nlm.nih.gov/gene/100520918", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520918", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520918", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LEVHWLS", "url": "https://omabrowser.org/oma/group/LEVHWLS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SP11", "url": "https://www.orthodb.org/?gene=A0A4X1SP11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10766", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10766", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10766:SF177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10766:SF177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02990", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02990", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013833642", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013833642", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SP11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SP11-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAU1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SGN4", "url": "https://www.uniprot.org/uniprotkb/F1SGN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SGN4-1", "url": "https://www.uniprot.org/uniprotkb/F1SGN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SGN5", "url": "https://www.uniprot.org/uniprotkb/F1SGN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SGN5-1", "url": "https://www.uniprot.org/uniprotkb/F1SGN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVLGHLRSWSCRWLPLLLLLGTGREPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLNSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSGGSGDDFEQGDNGWKIIHTDVFRFPPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASLFDAPCRTKNIAREIPPQPWYKSTLIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGVVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD", "length": 605, "header": "tr|A0A4X1SP11-1|A0A4X1SP11_PIG Isoform 1 of Transmembrane 9 superfamily member OS=Sus scrofa OX=9823 GN=TM9SF1 PE=1 SV=1 CANONICAL=A0A4X1SP11-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SP11-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11/entry#A0A4X1SP11-1", "sequence": { "sequence": "MTVLGHLRSWSCRWLPLLLLLGTGREPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLNSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSGGSGDDFEQGDNGWKIIHTDVFRFPPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASLFDAPCRTKNIAREIPPQPWYKSTLIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGVVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD", "length": 605, "header": "tr|A0A4X1SP11-1|A0A4X1SP11_PIG Isoform 1 of Transmembrane 9 superfamily member OS=Sus scrofa OX=9823 GN=TM9SF1 PE=1 SV=1 CANONICAL=A0A4X1SP11-1" }, "locus": { "chromosome": "7", "start_pos": 75109754, "end_pos": 75104916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058885.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058885.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044724.2", "url": "https://www.ensembl.org/id/ENSSSCP00000044724.2" } ] } }, { "isoform_ac": "A0A8W4FAU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11/entry#A0A8W4FAU1-1", "sequence": { "sequence": "MTVLGHLRSWSCRWLPLLLLLGTGREPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLNSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSGGSGDDFEQGDNGWKIIHTDVFRFPPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASLFDAPCRTKNIAREIPPQPWYKSTLIHMTVGGFLPFRYPPFIPWPSLSGSWP", "length": 490, "header": "tr|A0A8W4FAU1-1|A0A4X1SP11_PIG Computationally mapped isoform of Transmembrane 9 superfamily member OS=Sus scrofa OX=9823 GN=TM9SF1 PE=1 SV=1 CANONICAL=A0A4X1SP11-1" }, "locus": { "chromosome": "7", "start_pos": 75108842, "end_pos": 75104916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106720.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106720.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076387.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076387.1" } ] } }, { "isoform_ac": "F1SGN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11/entry#F1SGN4-1", "sequence": { "sequence": "MTVLGHLRSWSCRWLPLLLLLGTGREPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLNSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSGGSGDDFEQGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASLFDAPCRTKNIAREIPPQPWYKSTLIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGVVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD", "length": 568, "header": "tr|F1SGN4-1|F1SGN4_PIG Computationally mapped isoform of Transmembrane 9 superfamily member OS=Sus scrofa OX=9823 GN=IPO4 PE=1 SV=4 CANONICAL=A0A4X1SP11-1" }, "locus": { "chromosome": "7", "start_pos": 75109754, "end_pos": 75104916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002238.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002238.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002186.4", "url": "https://www.ensembl.org/id/ENSSSCP00000002186.4" } ] } }, { "isoform_ac": "F1SGN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11/entry#F1SGN5-1", "sequence": { "sequence": "MVLKSCWKPDLHLQSFKVSSCPGHTVVRRPTQPCLSSAPPDSSAGSSVLIMYTTATPDLNLAQAQLSLDTGRSLKDHGSSTVFGRCITYLVWGERPLMTVGRAIVRFRCLRMTVLGHLRSWSCRWLPLLLLLGTGREPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLNSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSGGSGDDFEQGDNGWKIIHTDVFRFPPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASLFDAPCRTKNIAREIPPQPWYKSTLIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGVVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD", "length": 716, "header": "tr|F1SGN5-1|F1SGN5_PIG Computationally mapped isoform of Transmembrane 9 superfamily member OS=Sus scrofa OX=9823 GN=IPO4 PE=1 SV=5 CANONICAL=A0A4X1SP11-1" }, "locus": { "chromosome": "7", "start_pos": 75109754, "end_pos": 75100273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002237.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002237.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002185.5", "url": "https://www.ensembl.org/id/ENSSSCP00000002185.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FAU1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAU1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520918", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520918", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MCZ2-1", "protein_name": "Transmembrane 9 superfamily member", "gene_name": "TM9SF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTVLGHPRSWSCRWWPLLLLLLLTGREPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRVLCHMQLSSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQSDNGWKIIHTDVFRFPPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTLVHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGTVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD", "length": 606 }, "evidence": [ { "id": "A0A4X1SP11", "url": "https://omabrowser.org/oma/group/A0A4X1SP11/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HDD7-1", "protein_name": "Transmembrane 9 superfamily member", "gene_name": "Tm9sf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTVLGHPRSWSCQCLPVLILLLGTGHGPGVEGVTHYKPGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKKILCHMQLSSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRSDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETSSGGSSDDFDQGDNGWKIIHTDVFRFPPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD", "length": 606 }, "evidence": [ { "id": "A0A4X1SP11", "url": "https://omabrowser.org/oma/group/A0A4X1SP11/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O15321-1", "protein_name": "Transmembrane 9 superfamily member 1", "gene_name": "TM9SF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVVGNPRSWSCQWLPILILLLGTGHGPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDNGWKIIHTDVFRFPPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD", "length": 606 }, "evidence": [ { "id": "A0A4X1SP11", "url": "https://omabrowser.org/oma/group/A0A4X1SP11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54ZW0-1", "protein_name": "Putative phagocytic receptor 1b", "gene_name": "phg1b", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRLQILLIYLICIIVSSIVLVESSNKHHFKENDEVPFYVNNVGPYSNPTETYEFYTLPFCKPSSISYKKTKLGEILQGDSAVLSDYQFPFKSSFENKQLCEYTLKKEDIEKFKKAIGEYYYAEMIYDDLPIFSFVGTVDDSDLTNIRYYLYNHIPFEFDYNGDQVIRVNIDTEHIKVIELSDQDEITLKLTYSAKWQPTEHEFSKRMDLYEEFFTKELEIHWLSVMNSFFLVVLLTAFLAIMIMKILKNDYSRYSKTDEEEDSDYQEDYGWKLVHGDVFRFPPYKNVFSAFYGIGWQFISIVCGILALSLFGMFYPNNGGNMYTAGIVLYALTSGISGYQSAKMYKNMGGNKWAWNIVLTATLFVAPLFIVVILSNTVAITWHSTVALPILTMIEVITIWLFVGFPLTVVGGIAGRRLSENFEAPCRTKNFPREVPPIQWYRRLPCQILIAGFLPFSAIYIELFYIFNSVWGHSTYTLYGILCLVFLILINVTVCITVALTYFQLSMEDHKWWWNSFINGGSTVVFIYMYSIYYYYYISHMYGLLQATFYFTYMLIVCFFFFILLGTVGFYSSLIFVKRIYRNLKSD", "length": 587 }, "evidence": [ { "id": "A0A4X1SP11", "url": "https://omabrowser.org/oma/group/A0A4X1SP11/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q66HF2-1", "protein_name": "Transmembrane 9 superfamily member 1", "gene_name": "Tm9sf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVLGHPRSWSCHCLPVLILLLGIGHGPRVEGVTHYKPGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRSDELLGLTHTYSVRWSETSVEHRSDRRRADDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETSSGGSSDDFDQGDNGWKIIHTDVFRFPPCRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPVTTILLLLTVWLLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPCAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD", "length": 589 }, "evidence": [ { "id": "A0A4X1SP11", "url": "https://omabrowser.org/oma/group/A0A4X1SP11/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DBU0-1", "protein_name": "Transmembrane 9 superfamily member 1", "gene_name": "Tm9sf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTVLGYPRSWSCHCLPVLILLLGIGHGPWVEGVTHYKPGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRSDELLGLTHTYSVRWSETSVEHRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETSSGGSSDDFDQGDNGWKIIHTDVFRFPPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTSSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD", "length": 606 }, "evidence": [ { "id": "A0A4X1SP11", "url": "https://omabrowser.org/oma/group/A0A4X1SP11/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 400, "end_pos": 402 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 558, "end_pos": 560 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SP46-1", "uniprot_ac": "A0A4X1SP46", "uniprot_id": "A0A4X1SP46_PIG", "mass": { "chemical_mass": 34526.0, "monoisotopic_mass": 34526.0 }, "refseq": { "ac": "XP_003123452", "name": "olfactory receptor 7A10-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123452" }, "gene_names": [ { "name": "LOC100525562", "type": "recommended", "evidence": [ { "id": "A0A4X1SP46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46" } ] }, { "name": "LOC100525562", "type": "synonym", "evidence": [ { "id": "XP_003123452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123452" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1SP46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7A10-like", "type": "synonym", "evidence": [ { "id": "XP_003123452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123452" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100525562", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46", "locus": {} } ], "crossref": [ { "id": "A0A4X1SP46", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SP46", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100525562", "url": "https://www.ncbi.nlm.nih.gov/gene/100525562", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525562", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525562", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KEPEFQL", "url": "https://omabrowser.org/oma/group/KEPEFQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SP46", "url": "https://www.orthodb.org/?gene=A0A4X1SP46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003123452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123452", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SP46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SP46-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPDNDTQISTFLLLGLSKERDFQPLIFGLFLSMYLITVFGNLLIILAVSSDSHLHTPMYFFLSNLSFVDICFTSTIIPKMLVNIQTENKVITYAGCITQLYFSTLFGGWDNFLLAVMAYDRFLAICHPLHYTVKMSPQFCGLLVLVSWILSVLNSLLQSLIVLQLSYTDMEIPHFFCDLNQMVKLGCSDTFLNDTVLYFSTGLLAGGPLAGILYSYSKIISSLCRISSAQGKYKAFSTCASHLSVVSLFYFSVLGVYLISAATHSSHSIAVASVMYSVVTPMLNPFIYSLRNKDIKGALKRFYEMAGIK", "length": 310, "header": "tr|A0A4X1SP46-1|A0A4X1SP46_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100525562 PE=3 SV=1 CANONICAL=A0A4X1SP46-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SP46-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46/entry#A0A4X1SP46-1", "sequence": { "sequence": "MGPDNDTQISTFLLLGLSKERDFQPLIFGLFLSMYLITVFGNLLIILAVSSDSHLHTPMYFFLSNLSFVDICFTSTIIPKMLVNIQTENKVITYAGCITQLYFSTLFGGWDNFLLAVMAYDRFLAICHPLHYTVKMSPQFCGLLVLVSWILSVLNSLLQSLIVLQLSYTDMEIPHFFCDLNQMVKLGCSDTFLNDTVLYFSTGLLAGGPLAGILYSYSKIISSLCRISSAQGKYKAFSTCASHLSVVSLFYFSVLGVYLISAATHSSHSIAVASVMYSVVTPMLNPFIYSLRNKDIKGALKRFYEMAGIK", "length": 310, "header": "tr|A0A4X1SP46-1|A0A4X1SP46_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100525562 PE=3 SV=1 CANONICAL=A0A4X1SP46-1" }, "locus": { "chromosome": "2", "start_pos": 63349358, "end_pos": 63348429, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015082.3", "url": "https://www.ensembl.org/id/ENSSSCT00000015082.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014677.2", "url": "https://www.ensembl.org/id/ENSSSCP00000014677.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525562", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525562", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SP61-1", "uniprot_ac": "A0A4X1SP61", "uniprot_id": "A0A4X1SP61_PIG", "mass": { "chemical_mass": 7851.0, "monoisotopic_mass": 7851.0 }, "refseq": { "ac": "XP_003134421", "name": "beta-defensin 123", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134421" }, "gene_names": [ { "name": "DEFB123", "type": "recommended", "evidence": [ { "id": "A0A4X1SP61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61" } ] }, { "name": "DEFB123", "type": "synonym", "evidence": [ { "id": "XP_003134421", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134421" } ] } ], "protein_names": [ { "name": "Beta-defensin", "type": "recommended", "evidence": [ { "id": "A0A4X1SP61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61/entry#names_and_taxonomy" } ] }, { "name": "beta-defensin 123", "type": "synonym", "evidence": [ { "id": "XP_003134421", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134421" } ] } ], "function": [ { "annotation": "Has antibacterial activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61#function" }, { "database": "UniProtKB", "id": "ARBA00002878", "url": "https://www.uniprot.org/uniprotkb/ARBA00002878#function" }, { "database": "UniProtKB", "id": "RU231113", "url": "https://www.uniprot.org/uniprotkb/RU231113#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DEFB123", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61", "locus": { "chromosome": "17", "start_pos": 35191549, "end_pos": 35185273, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000056400", "url": "https://www.ensembl.org/id/ENSSSCG00000056400" } ] } } ], "crossref": [ { "id": "A0A4X1SP61", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SP61", "database": "AlphaFoldDB", "categories": [] }, { "id": "100521232", "url": "https://www.ncbi.nlm.nih.gov/gene/100521232", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050544", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050544", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521232", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521232", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RCWNLHG", "url": "https://omabrowser.org/oma/group/RCWNLHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SP61", "url": "https://www.orthodb.org/?gene=A0A4X1SP61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15001:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15001:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1461957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1461957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1461973", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1461973", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003134421", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134421", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SP61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SP61-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLLLLTLATLLLLSQLSPGGTKKCWNLHGKCRQKCFGKERVYVYCTNNKMCCVKPKYQPRENPWKF", "length": 67, "header": "tr|A0A4X1SP61-1|A0A4X1SP61_PIG Isoform 1 of Beta-defensin OS=Sus scrofa OX=9823 GN=DEFB123 PE=3 SV=1 CANONICAL=A0A4X1SP61-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SP61-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61/entry#A0A4X1SP61-1", "sequence": { "sequence": "MKLLLLTLATLLLLSQLSPGGTKKCWNLHGKCRQKCFGKERVYVYCTNNKMCCVKPKYQPRENPWKF", "length": 67, "header": "tr|A0A4X1SP61-1|A0A4X1SP61_PIG Isoform 1 of Beta-defensin OS=Sus scrofa OX=9823 GN=DEFB123 PE=3 SV=1 CANONICAL=A0A4X1SP61-1" }, "locus": { "chromosome": "17", "start_pos": 35190545, "end_pos": 35185472, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096921.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096921.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075387.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075387.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521232", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521232", "resource": "KEGG Pathway" }, { "id": "R-SSC-1461957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1461957", "resource": "Reactome", "description": "Beta defensins" }, { "id": "R-SSC-1461973", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1461973", "resource": "Reactome", "description": "Defensins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HE33-1", "protein_name": "Beta-defensin", "gene_name": "Defb123", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKLLLLTLAALLLLSQLTPGDAQKCWNLNGKCRHRCSRKESVYVYCTNGKMCCVKPKYQPKPKPWMF", "length": 67 }, "evidence": [ { "id": "A0A4X1SP61", "url": "https://omabrowser.org/oma/group/A0A4X1SP61/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8K3U4-1", "protein_name": "Beta-defensin 36", "gene_name": "Defb36", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLLLLTLAALLLVSQLTPGDAQKCWNLHGKCRHRCSRKESVYVYCTNGKMCCVKPKYQPKPKPWMF", "length": 67 }, "evidence": [ { "id": "A0A4X1SP61", "url": "https://omabrowser.org/oma/group/A0A4X1SP61/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N688-1", "protein_name": "Beta-defensin 123", "gene_name": "DEFB123", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLLLLTLTVLLLLSQLTPGGTQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPKYQPKERWWPF", "length": 67 }, "evidence": [ { "id": "A0A4X1SP61", "url": "https://omabrowser.org/oma/group/A0A4X1SP61/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61" } ], "pmid": "" }, { "name": "killing of cells of another organism", "id": "GO:0031640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031640", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "membrane destabilizing activity", "id": "GO:0140912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140912", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SP61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SP61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SP61" }, { "id": "PF13841", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13841" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-defensin", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 53, "start_aa": "Lys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SRK5-1", "uniprot_ac": "A0A4X1SRK5", "uniprot_id": "A0A4X1SRK5_PIG", "mass": { "chemical_mass": 30035.0, "monoisotopic_mass": 30035.0 }, "refseq": { "ac": "XP_003123751", "name": "ribosome biogenesis protein NSA2 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123751" }, "gene_names": [ { "name": "NSA2", "type": "recommended", "evidence": [ { "id": "A0A4X1SRK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5" } ] }, { "name": "NSA2", "type": "synonym", "evidence": [ { "id": "XP_003123751", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123751" } ] } ], "protein_names": [ { "name": "Ribosome biogenesis protein NSA2 homolog", "type": "recommended", "evidence": [ { "id": "A0A4X1SRK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5/entry#names_and_taxonomy" } ] }, { "name": "ribosome biogenesis protein NSA2 homolog", "type": "synonym", "evidence": [ { "id": "XP_003123751", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123751" } ] } ], "function": [ { "annotation": "Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5#function" }, { "database": "UniProtKB", "id": "RU367114", "url": "https://www.uniprot.org/uniprotkb/RU367114#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NSA2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5", "locus": {} } ], "crossref": [ { "id": "cd11381", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11381", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100517810", "url": "https://www.ncbi.nlm.nih.gov/gene/100517810", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039411", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039411", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517810", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517810", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TNTPEND", "url": "https://omabrowser.org/oma/group/TNTPEND/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SRK5", "url": "https://www.orthodb.org/?gene=A0A4X1SRK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12642", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12642", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003123751", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123751", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SPX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SPX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SRK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQNEYIELHRKRYGYRLDYHEKKRKKEGREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKNDEKTPQGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV", "length": 260, "header": "tr|A0A4X1SRK5-1|A0A4X1SRK5_PIG Isoform 1 of Ribosome biogenesis protein NSA2 homolog OS=Sus scrofa OX=9823 GN=NSA2 PE=3 SV=1 CANONICAL=A0A4X1SRK5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SPX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5/entry#A0A4X1SPX1-1", "sequence": { "sequence": "MPQNEYIELHRKRYGYRLDYHEKKRKKEGREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKNDEKTPQGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMENMPRLPTILKMMDA", "length": 189, "header": "tr|A0A4X1SPX1-1|A0A4X1SPX1_PIG Computationally mapped isoform of NSA2 ribosome biosis factor OS=Sus scrofa OX=9823 GN=NSA2 PE=4 SV=1 CANONICAL=A0A4X1SRK5-1" }, "locus": { "chromosome": "2", "start_pos": 83851041, "end_pos": 83844078, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015376.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015376.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014968.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014968.3" } ] } }, { "isoform_ac": "A0A4X1SRK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5/entry#A0A4X1SRK5-1", "sequence": { "sequence": "MPQNEYIELHRKRYGYRLDYHEKKRKKEGREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKNDEKTPQGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV", "length": 260, "header": "tr|A0A4X1SRK5-1|A0A4X1SRK5_PIG Isoform 1 of Ribosome biogenesis protein NSA2 homolog OS=Sus scrofa OX=9823 GN=NSA2 PE=3 SV=1 CANONICAL=A0A4X1SRK5-1" }, "locus": { "chromosome": "2", "start_pos": 83851061, "end_pos": 83844078, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087948.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087948.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060892.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060892.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517810", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517810", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7I5Q8-1", "protein_name": "Ribosome biogenesis protein NSA2 homolog", "gene_name": "Nsa2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPQNEYIELHRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKNDDKTPQGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV", "length": 260 }, "evidence": [ { "id": "A0A4X1SRK5", "url": "https://omabrowser.org/oma/group/A0A4X1SRK5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1QDL2-1", "protein_name": "Ribosome biogenesis protein NSA2 homolog", "gene_name": "nsa2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPQNEHIELHRKRHGYRLDHHEKKRKKESREAHERSHKARKMIGLKAKLYHKQRHAEKIQMKKTIKMHEQRKSKQKDDDKTPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRQKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFNKAHVTHPELKATFCLPILGVKKNPSSSLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV", "length": 260 }, "evidence": [ { "id": "A0A4X1SRK5", "url": "https://omabrowser.org/oma/group/A0A4X1SRK5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O76994-1", "protein_name": "Ribosome biogenesis protein NSA2 homolog", "gene_name": "Ip259", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPQNEYMERHRKLYGRRLDYEERKRKKEARLPKDRARKARKLRGIKAKLFNKERRNEKIQIKKKIQAHEEKKVKKQEEKVEDGALPHYLLDRGIQSSAKVLSNMIKQKRKEKAGKWDVPIPKVRAQSDAEVFKVLKTGKTKRKAWKRMVTKVTFVGENFTRKPPKFERFIRPMGLRMKKAHVTHPELKATFNLPIIGVKKNPSSPMFTSLGVITKGTVIEVNISELGLVTQTGKVVWGKYAQVTNNPENDGVINAVLLV", "length": 259 }, "evidence": [ { "id": "A0A4X1SRK5", "url": "https://omabrowser.org/oma/group/A0A4X1SRK5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O95478-1", "protein_name": "Ribosome biogenesis protein NSA2 homolog", "gene_name": "NSA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPQNEYIELHRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKNDEKTPQGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV", "length": 260 }, "evidence": [ { "id": "A0A4X1SRK5", "url": "https://omabrowser.org/oma/group/A0A4X1SRK5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P40078-1", "protein_name": "Ribosome biogenesis protein NSA2", "gene_name": "NSA2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPQNDYIERHIKQHGKRLDHEERKRKREARESHKISERAQKLTGWKGKQFAKKRYAEKVSMRKKIKAHEQSKVKGSSKPLDTDGDALPTYLLDREQNNTAKAISSSIKQKRLEKADKFSVPLPKVRGISEEEMFKVIKTGKSRSKSWKRMITKHTFVGEGFTRRPVKMERIIRPSALRQKKANVTHPELGVTVFLPILAVKKNPQSPMYTQLGVLTKGTIIEVNVSELGMVTAGGKVVWGKYAQVTNEPDRDGCVNAVLLV", "length": 261 }, "evidence": [ { "id": "A0A4X1SRK5", "url": "https://omabrowser.org/oma/group/A0A4X1SRK5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3SX11-1", "protein_name": "Ribosome biogenesis protein NSA2 homolog", "gene_name": "NSA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPQNEYIELHRKRYGYRLDYHEKKRKKEGREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKNDEKTPQGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV", "length": 260 }, "evidence": [ { "id": "A0A4X1SRK5", "url": "https://omabrowser.org/oma/group/A0A4X1SRK5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54GN8-1", "protein_name": "Ribosome biogenesis protein NSA2 homolog", "gene_name": "nsa2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPQGDHIELHQKRFGRRLDHYEKVRKKTARAAHKRSAIAQKVTGLKAKLYNKKRYSEKAEMKKTIAMHQERTNKKASDDKVKEGAVPAYLLDREGVSRAKVLSNMVKQKRKEKAGKWDVPLPKVRAISEDEMFKVVKSGKRQKKAWKRFVTKVTFVGEGFTRKPPKYERFIRPTGLRFKKAHVTHPELKSTFYLDILSVKKNPQSPTYTQLGVITKGTILEVNVSDLGLVTQTGKVVWGKMAQVTNNPENDGCINAVLLV", "length": 260 }, "evidence": [ { "id": "A0A4X1SRK5", "url": "https://omabrowser.org/oma/group/A0A4X1SRK5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9CR47-1", "protein_name": "Ribosome biogenesis protein NSA2 homolog", "gene_name": "Nsa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPQNEYIELHRKRYGYRLDYHEKKRKKEGREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIKMHEKRNTKQKDDEKTPQGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV", "length": 260 }, "evidence": [ { "id": "A0A4X1SRK5", "url": "https://omabrowser.org/oma/group/A0A4X1SRK5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FNH2-1", "protein_name": "Ribosome biogenesis protein NSA2 homolog", "gene_name": "MHF15.12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPQGDYIDLHRKRNGYRLDHFERKRKKEAREVHKHSTMAQKSLGIKGKMIAKKNYAEKALMKKTLKMHEESSSRRKADENVQEGAVPAYLLDREDTTRAKVLSNTIKQKRKEKAGKWEVPLPKVRPVAEDEMFRVIRSGKRKTKQWKRMVTKATFVGPAFTRKPPKYERFIRPSGLRFTKAHVTHPELKCTFCLEIIGIKKNPNGPMYTSLGVMTRGTIIEVNVSELGLVTPAGKVVWGKYAQVTNNPENDGCINAVLLV", "length": 260 }, "evidence": [ { "id": "A0A4X1SRK5", "url": "https://omabrowser.org/oma/group/A0A4X1SRK5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA", "id": "GO:0000470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000470", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 223, "end_pos": 225 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SQF9-1", "uniprot_ac": "A0A4X1SQF9", "uniprot_id": "A0A4X1SQF9_PIG", "mass": { "chemical_mass": 34953.0, "monoisotopic_mass": 34953.0 }, "refseq": { "ac": "XP_013849888", "name": "ETS homologous factor isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849888" }, "gene_names": [ { "name": "EHF", "type": "recommended", "evidence": [ { "id": "A0A4X1SQF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ] }, { "name": "EHF", "type": "synonym", "evidence": [ { "id": "XP_013849888", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849888" } ] } ], "protein_names": [ { "name": "ETS homologous factor", "type": "recommended", "evidence": [ { "id": "A0A4X1SQF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9/entry#names_and_taxonomy" } ] }, { "name": "ETS domain-containing transcription factor", "type": "synonym", "evidence": [ { "id": "A0A4X1SQF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9/entry#names_and_taxonomy" } ] }, { "name": "ETS homologous factor isoform X3", "type": "synonym", "evidence": [ { "id": "XP_013849888", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849888" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EHF", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9", "locus": { "chromosome": "2", "start_pos": 26291480, "end_pos": 26340245, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013300", "url": "https://www.ensembl.org/id/ENSSSCG00000013300" } ] } } ], "crossref": [ { "id": "cd08539", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08539", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100526094", "url": "https://www.ncbi.nlm.nih.gov/gene/100526094", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003118", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003118", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SQF9", "url": "https://www.orthodb.org/?gene=A0A4X1SQF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013849888", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849888", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SQF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SRX3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SRX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MILEGSGVMNLNPSNNLLHQPPAWTDSYPTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQHLLDTNQLDASCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTDPTIMNSWKEENYLFDPNYGSTVDLLDSKTFCRAQISMTTTGHLPVAESPDMKKEQDHPTKSHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGIFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN", "length": 300, "header": "tr|A0A4X1SQF9-1|A0A4X1SQF9_PIG Isoform 1 of ETS homologous factor OS=Sus scrofa OX=9823 GN=EHF PE=3 SV=1 CANONICAL=A0A4X1SQF9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SQF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9/entry#A0A4X1SQF9-1", "sequence": { "sequence": "MILEGSGVMNLNPSNNLLHQPPAWTDSYPTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQHLLDTNQLDASCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTDPTIMNSWKEENYLFDPNYGSTVDLLDSKTFCRAQISMTTTGHLPVAESPDMKKEQDHPTKSHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGIFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN", "length": 300, "header": "tr|A0A4X1SQF9-1|A0A4X1SQF9_PIG Isoform 1 of ETS homologous factor OS=Sus scrofa OX=9823 GN=EHF PE=3 SV=1 CANONICAL=A0A4X1SQF9-1" }, "locus": { "chromosome": "2", "start_pos": 26310481, "end_pos": 26291710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078467.1", "url": "https://www.ensembl.org/id/ENSSSCT00000078467.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069624.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069624.1" } ] } }, { "isoform_ac": "A0A4X1SRX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9/entry#A0A4X1SRX3-1", "sequence": { "sequence": "MILEGSGVMNLNPSNNLLHQPPAWTDSYPTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQHLLDTNQLDASCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTDPTIMNSWKEENYLFDPNYGSTVAESPDMKKEQDHPTKSHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGIFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN", "length": 277, "header": "tr|A0A4X1SRX3-1|A0A4X1SRX3_PIG Computationally mapped isoform of ETS homologous factor OS=Sus scrofa OX=9823 GN=EHF PE=3 SV=1 CANONICAL=A0A4X1SQF9-1" }, "locus": { "chromosome": "2", "start_pos": 26310481, "end_pos": 26291710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083760.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083760.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072217.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072217.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ], "pmid": "" }, { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQF9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SQF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" }, { "id": "PS50061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ETS", "eco_id": "ECO_0000259", "start_pos": 207, "end_pos": 289, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SQF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQF9" }, { "id": "PS51433", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51433" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PNT", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 115, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 254, "end_pos": 256 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SQM6-1", "uniprot_ac": "A0A4X1SQM6", "uniprot_id": "A0A4X1SQM6_PIG", "mass": { "chemical_mass": 9937.0, "monoisotopic_mass": 9937.0 }, "refseq": { "ac": "XP_005673329", "name": "U6 snRNA-associated Sm-like protein LSm5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005673329" }, "gene_names": [ { "name": "LSM5", "type": "recommended", "evidence": [ { "id": "A0A4X1SQM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ] }, { "name": "LSM5", "type": "synonym", "evidence": [ { "id": "XP_005673329", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005673329" } ] } ], "protein_names": [ { "name": "U6 snRNA-associated Sm-like protein LSm5", "type": "recommended", "evidence": [ { "id": "A0A4X1SQM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6/entry#names_and_taxonomy" } ] }, { "name": "U6 snRNA-associated Sm-like protein LSm5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005673329", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005673329" } ] } ], "function": [ { "annotation": "Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6#function" }, { "database": "UniProtKB", "id": "RU365055", "url": "https://www.uniprot.org/uniprotkb/RU365055#function" } ] }, { "annotation": "Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6#function" }, { "database": "UniProtKB", "id": "ARBA00056431", "url": "https://www.uniprot.org/uniprotkb/ARBA00056431#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LSM5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6", "locus": { "chromosome": "18", "start_pos": 40755906, "end_pos": 40752461, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026064", "url": "https://www.ensembl.org/id/ENSSSCG00000026064" } ] } } ], "crossref": [ { "id": "A0A4X1SQM6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SQM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026064", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026064", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01732", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01732", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100624767", "url": "https://www.ncbi.nlm.nih.gov/gene/100624767", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624767", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624767", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YETTPQG", "url": "https://omabrowser.org/oma/group/YETTPQG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SQM6", "url": "https://www.orthodb.org/?gene=A0A4X1SQM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20971", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20971", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20971:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20971:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-430039", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-430039", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005673329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005673329", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SQM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RD92", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RD92-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAANATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVNMVLEDVTEFEITPEGRRITKLDQILLNGNNITMLVPGGEGPEV", "length": 91, "header": "tr|A0A4X1SQM6-1|A0A4X1SQM6_PIG Isoform 1 of U6 snRNA-associated Sm-like protein LSm5 OS=Sus scrofa OX=9823 GN=LSM5 PE=3 SV=1 CANONICAL=A0A4X1SQM6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SQM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6/entry#A0A4X1SQM6-1", "sequence": { "sequence": "MAANATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVNMVLEDVTEFEITPEGRRITKLDQILLNGNNITMLVPGGEGPEV", "length": 91, "header": "tr|A0A4X1SQM6-1|A0A4X1SQM6_PIG Isoform 1 of U6 snRNA-associated Sm-like protein LSm5 OS=Sus scrofa OX=9823 GN=LSM5 PE=3 SV=1 CANONICAL=A0A4X1SQM6-1" }, "locus": { "chromosome": "18", "start_pos": 40755675, "end_pos": 40752483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028105.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028105.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025145.1", "url": "https://www.ensembl.org/id/ENSSSCP00000025145.1" } ] } }, { "isoform_ac": "A0A5G2RD92-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6/entry#A0A5G2RD92-1", "sequence": { "sequence": "MAANATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVSILLKMKSHQKEEELLS", "length": 64, "header": "tr|A0A5G2RD92-1|A0A4X1SQM6_PIG Computationally mapped isoform of U6 snRNA-associated Sm-like protein LSm5 OS=Sus scrofa OX=9823 GN=LSM5 PE=3 SV=1 CANONICAL=A0A4X1SQM6-1" }, "locus": { "chromosome": "18", "start_pos": 40755228, "end_pos": 40752483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087262.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087262.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068664.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068664.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RD92", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RD92" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624767", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624767", "resource": "KEGG Pathway" }, { "id": "R-SSC-430039", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-430039", "resource": "Reactome", "description": "mRNA decay by 5' to 3' exoribonuclease" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZBJ0-1", "protein_name": "U6 snRNA-associated Sm-like protein LSm5", "gene_name": "Lsm5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAANATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVSILFISVCLFSEITPEGRRITKLDQILLNGNNITMLVPGGEGPEV", "length": 92 }, "evidence": [ { "id": "A0A4X1SQM6", "url": "https://omabrowser.org/oma/group/A0A4X1SQM6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62322-1", "protein_name": "U6 snRNA-associated Sm-like protein LSm5", "gene_name": "Lsm5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAANATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVNMVLEDVTEFEITPEGRRITKLDQILLNGNNITMLVPGGEGPEV", "length": 91 }, "evidence": [ { "id": "A0A4X1SQM6", "url": "https://omabrowser.org/oma/group/A0A4X1SQM6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2HJH0-1", "protein_name": "U6 snRNA-associated Sm-like protein LSm5", "gene_name": "LSM5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAANATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVNMVLEDVTEFEITPEGRRITKLDQILLNGNNITMLVPGGEGPEV", "length": 91 }, "evidence": [ { "id": "A0A4X1SQM6", "url": "https://omabrowser.org/oma/group/A0A4X1SQM6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55EX5-1", "protein_name": "Probable U6 snRNA-associated Sm-like protein LSm5", "gene_name": "lsm5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSEVENSNTVDLQSQLLPLELIEKCIGSRIWIAMKNDKEFVGTLLGFDAYVNIFLKDVTEYEYTPEGLKTVKLDNILLNGNHVCLLVPGGEGPKVKA", "length": 97 }, "evidence": [ { "id": "A0A4X1SQM6", "url": "https://omabrowser.org/oma/group/A0A4X1SQM6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9FKB0-1", "protein_name": "Sm-like protein LSM5", "gene_name": "LSM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MANNPSQLLPSELIDRCIGSKIWVIMKGDKELVGILKGFDVYVNMVLEDVTEYEITAEGRRVTKLDQILLNGNNIAILVPGGSPEDGE", "length": 88 }, "evidence": [ { "id": "A0A4X1SQM6", "url": "https://omabrowser.org/oma/group/A0A4X1SQM6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VRT7-1", "protein_name": "U6 snRNA-associated Sm-like protein LSm5", "gene_name": "BcDNA:RE60135", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTAVPPPSNISTLMPLELVDKCIGSRIHIIMKNDKEMVGTLLGFDDFVNMLLDDVTEYENTPDGRRITKLDQILLNGNNITMLVPGGELAE", "length": 91 }, "evidence": [ { "id": "A0A4X1SQM6", "url": "https://omabrowser.org/oma/group/A0A4X1SQM6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y4Y9-1", "protein_name": "U6 snRNA-associated Sm-like protein LSm5", "gene_name": "LSM5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAANATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVNMVLEDVTEFEITPEGRRITKLDQILLNGNNITMLVPGGEGPEV", "length": 91 }, "evidence": [ { "id": "A0A4X1SQM6", "url": "https://omabrowser.org/oma/group/A0A4X1SQM6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "pmid": "" }, { "name": "Lsm2-8 complex", "id": "GO:0120115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120115", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "pmid": "" }, { "name": "U6 snRNP", "id": "GO:0005688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005688", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "pmid": "" }, { "name": "Lsm1-7-Pat1 complex", "id": "GO:1990726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990726", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQM6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SQM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQM6" }, { "id": "PS52002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sm", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 88, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 4, "end_pos": 6 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SQN5-1", "uniprot_ac": "A0A4X1SQN5", "uniprot_id": "A0A4X1SQN5_PIG", "mass": { "chemical_mass": 20897.0, "monoisotopic_mass": 20897.0 }, "refseq": {}, "gene_names": [ { "name": "TRAT1", "type": "recommended", "evidence": [ { "id": "A0A4X1SQN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5" } ] } ], "protein_names": [ { "name": "T cell receptor associated transmembrane adaptor 1", "type": "synonym", "evidence": [ { "id": "A0A4X1SQN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQN5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TRAT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5", "locus": { "chromosome": "13", "start_pos": 150629944, "end_pos": 150666598, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000023842", "url": "https://www.ensembl.org/id/ENSSSCG00000023842" } ] } } ], "crossref": [ { "id": "A0A4X1SQN5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SQN5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100620198", "url": "https://www.ncbi.nlm.nih.gov/gene/100620198", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100620198", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620198", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DEDCYEQ", "url": "https://omabrowser.org/oma/group/DEDCYEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SQN5", "url": "https://www.orthodb.org/?gene=A0A4X1SQN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15951", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15951", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15951:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15951:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15330", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15330", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1257604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-202424", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202424", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6811558", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SQN5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SQN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SSF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SSF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSENGCQFYVWAILAFLGLALTISLIFNISHYVEKQRRDKVYLYSDDYIPREDEYDFEDTPIYGNLGNVISEPVDENCYEQMKARPERSVNEPKEDTPPAQETEEKLCYASLDRSSEGKRKKPKKQKSYLSDRNEDGQAPSLSKTTLVDGFSLESQTIEENIHDDPIRLFGLIRAQKKNVN", "length": 181, "header": "tr|A0A4X1SQN5-1|A0A4X1SQN5_PIG Isoform 1 of T cell receptor associated transmembrane adaptor 1 OS=Sus scrofa OX=9823 GN=TRAT1 PE=4 SV=1 CANONICAL=A0A4X1SQN5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SQN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5/entry#A0A4X1SQN5-1", "sequence": { "sequence": "MSENGCQFYVWAILAFLGLALTISLIFNISHYVEKQRRDKVYLYSDDYIPREDEYDFEDTPIYGNLGNVISEPVDENCYEQMKARPERSVNEPKEDTPPAQETEEKLCYASLDRSSEGKRKKPKKQKSYLSDRNEDGQAPSLSKTTLVDGFSLESQTIEENIHDDPIRLFGLIRAQKKNVN", "length": 181, "header": "tr|A0A4X1SQN5-1|A0A4X1SQN5_PIG Isoform 1 of T cell receptor associated transmembrane adaptor 1 OS=Sus scrofa OX=9823 GN=TRAT1 PE=4 SV=1 CANONICAL=A0A4X1SQN5-1" }, "locus": { "chromosome": "13", "start_pos": 150666399, "end_pos": 150632262, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024639.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024639.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024081.1", "url": "https://www.ensembl.org/id/ENSSSCP00000024081.1" } ] } }, { "isoform_ac": "A0A4X1SSF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5/entry#A0A4X1SSF0-1", "sequence": { "sequence": "MSDKVYLYSDDYIPREDEYDFEDTPIYGNLGNVISEPVDENCYEQMKARPERSVNEPKEDTPPAQETEEKLCYASLDRSSEGKRKKPKKQKSYLSDRNEDGQAPSLSKTTLVDGFSLESQTIEENIHDDPIRLFGLIRAQKKNVN", "length": 145, "header": "tr|A0A4X1SSF0-1|A0A4X1SSF0_PIG Computationally mapped isoform of T cell receptor associated transmembrane adaptor 1 OS=Sus scrofa OX=9823 GN=TRAT1 PE=4 SV=1 CANONICAL=A0A4X1SQN5-1" }, "locus": { "chromosome": "13", "start_pos": 150666399, "end_pos": 150632262, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069904.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069904.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066284.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066284.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQN5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100620198", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620198", "resource": "KEGG Pathway" }, { "id": "R-SSC-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-SSC-202424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202424", "resource": "Reactome", "description": "Downstream TCR signaling" }, { "id": "R-SSC-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9S1P0-1", "protein_name": "T cell receptor associated transmembrane adaptor 1", "gene_name": "TRAT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSKARGNAECHFSIWAILAFLGLALTISLIFNIFHCVEKQRQEKICTYSDDYFPREDEYDLEDSPIYGNVDNVALEPVDENCYEQMKARPDRSVNKLQDAPPSQETAVRVCYASLDHNNEGKRRKPRKQKTHLSDKDEEGQMHAKDISLSKTTLVDSYPPESEAIEENIHDDPIRLFGLIRAQKESLHSLDYDLAQ", "length": 197 }, "evidence": [ { "id": "A0A4X1SQN5", "url": "https://omabrowser.org/oma/group/A0A4X1SQN5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NRE1-1", "protein_name": "T cell receptor associated transmembrane adaptor 1", "gene_name": "TRAT1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDCHYSVWGVLAFLSLALIFSLILNISHYMKKKREAKMYKDNEDNTQSYDDCYTGDDPVYGNLSQDVLEECCYEQMKSQPQRPVNELQVESADQMCYASLDHSTKGKRRKPRRKKDPPLEDEEERLSKSTITASKVCIYLNSEQLAAENTANVEAIHDDPVRLMGLIHRTNGENI", "length": 175 }, "evidence": [ { "id": "A0A4X1SQN5", "url": "https://omabrowser.org/oma/group/A0A4X1SQN5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F7F6T0-1", "protein_name": "T cell receptor associated transmembrane adaptor 1", "gene_name": "Trat1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHTGSSKKTSMSGNSGCPFFLWGLLAFLGLALVISLIFNVSHYVEKQRRDKMYRYSDDYIPRAEEYYEDAPIYGNLENIIPEPLDEDCYEQMKARPQRSASDAQEVVAPAQVPAEAQICYASLDHSMKGKRRRPRKQNTNLSDRGKDAQDCTMGANVSQNNMVESFPPDNQVVEESIHDDPARLFGLIRAKREPVI", "length": 196 }, "evidence": [ { "id": "A0A4X1SQN5", "url": "https://omabrowser.org/oma/group/A0A4X1SQN5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UU67-1", "protein_name": "T-cell receptor-associated transmembrane adapter 1", "gene_name": "Trat1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGSSGCPFFLWGLLAFLGLALVISLIFNISHYVEKQRRDEIYRYSDDYIPRVDEYYVEDAPIYGNLENIIPEPLDENCYEQMKGRPQRSASDPQEVAAPAQVPAEAQMCYASLDHSVKGKRRRPRKQNTNVSDRGKDTQVYTMDANVSQINMVESFPPDNQVVEESIHDDPARLFGLIRAKREPVI", "length": 187 }, "evidence": [ { "id": "A0A4X1SQN5", "url": "https://omabrowser.org/oma/group/A0A4X1SQN5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6PIZ9-1", "protein_name": "T-cell receptor-associated transmembrane adapter 1", "gene_name": "TRAT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGISGCPFFLWGLLALLGLALVISLIFNISHYVEKQRQDKMYSYSSDHTRVDEYYIEDTPIYGNLDDMISEPMDENCYEQMKARPEKSVNKMQEATPSAQATNETQMCYASLDHSVKGKRRKPRKQNTHFSDKDGDEQLHAIDASVSKTTLVDSFSPESQAVEENIHDDPIRLFGLIRAKREPIN", "length": 186 }, "evidence": [ { "id": "A0A4X1SQN5", "url": "https://omabrowser.org/oma/group/A0A4X1SQN5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQN5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQN5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of T cell receptor signaling pathway", "id": "GO:0050862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050862", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQN5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5" } ], "pmid": "" }, { "name": "negative regulation of receptor recycling", "id": "GO:0001920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001920", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SQN5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SQN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 28, "end_pos": 30 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SRU3-1", "uniprot_ac": "A0A4X1SRU3", "uniprot_id": "A0A4X1SRU3_PIG", "mass": { "chemical_mass": 47366.0, "monoisotopic_mass": 47366.0 }, "refseq": { "ac": "XP_020950042", "name": "26S protease regulatory subunit 6B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950042" }, "gene_names": [ { "name": "PSMC4", "type": "recommended", "evidence": [ { "id": "A0A4X1SRU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3" } ] }, { "name": "PSMC4", "type": "synonym", "evidence": [ { "id": "XP_020950042", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950042" } ] } ], "protein_names": [ { "name": "26S proteasome regulatory subunit 6B", "type": "recommended", "evidence": [ { "id": "A0A4X1SRU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3/entry#names_and_taxonomy" } ] }, { "name": "26S protease regulatory subunit 6B", "type": "synonym", "evidence": [ { "id": "XP_020950042", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950042" } ] }, { "name": "26S proteasome AAA-ATPase subunit RPT3", "type": "synonym", "evidence": [ { "id": "A0A4X1SRU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3/entry#names_and_taxonomy" } ] }, { "name": "Proteasome 26S subunit ATPase 4", "type": "synonym", "evidence": [ { "id": "A0A4X1SRU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRU3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3#function" }, { "database": "UniProtKB", "id": "ARBA00002699", "url": "https://www.uniprot.org/uniprotkb/ARBA00002699#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRU3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PSMC4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3", "locus": { "chromosome": "6", "start_pos": 48416215, "end_pos": 48406376, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000039235", "url": "https://www.ensembl.org/id/ENSSSCG00000039235" } ] } } ], "crossref": [ { "id": "A0A4X1SRU3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SRU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19502", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19502", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110260986", "url": "https://www.ncbi.nlm.nih.gov/gene/110260986", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110260986", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110260986", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDIGGMD", "url": "https://omabrowser.org/oma/group/QDIGGMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SRU3", "url": "https://www.orthodb.org/?gene=A0A4X1SRU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23073", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23073", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16450", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16450", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1169091", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1169091", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1234176", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1234176", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1236978", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1236978", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174084", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174084", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174154", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174154", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174178", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174184", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174184", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-187577", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-187577", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-202424", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202424", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2871837", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2871837", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-349425", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-349425", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-350562", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-350562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-382556", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-382556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-450408", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4608870", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4608870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4641257", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4641257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4641258", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4641258", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5358346", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358346", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5607761", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5607761", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5607764", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5607764", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5610780", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5610780", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5610785", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5610785", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5632684", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5632684", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5658442", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5658442", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5668541", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5668541", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5676590", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5676590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5687128", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5689603", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68867", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68867", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68949", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68949", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-69017", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69017", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-69481", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69481", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-69601", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69601", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-75815", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75815", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8852276", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8852276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8854050", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854050", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8939236", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8939902", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939902", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8941858", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8941858", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8948751", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8948751", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9020702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9020702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9755511", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9755511", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9766229", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9766229", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9907900", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9907900", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9931269", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9931269", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9932298", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9932298", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020950042", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950042", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SRU3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SRU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK", "length": 418, "header": "tr|A0A4X1SRU3-1|A0A4X1SRU3_PIG Isoform 1 of 26S proteasome regulatory subunit 6B OS=Sus scrofa OX=9823 GN=PSMC4 PE=3 SV=1 CANONICAL=A0A4X1SRU3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SRU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3/entry#A0A4X1SRU3-1", "sequence": { "sequence": "MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK", "length": 418, "header": "tr|A0A4X1SRU3-1|A0A4X1SRU3_PIG Isoform 1 of 26S proteasome regulatory subunit 6B OS=Sus scrofa OX=9823 GN=PSMC4 PE=3 SV=1 CANONICAL=A0A4X1SRU3-1" }, "locus": { "chromosome": "6", "start_pos": 48414341, "end_pos": 48406400, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037756.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037756.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051264.1", "url": "https://www.ensembl.org/id/ENSSSCP00000051264.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRU3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110260986", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110260986", "resource": "KEGG Pathway" }, { "id": "R-SSC-1169091", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1169091", "resource": "Reactome", "description": "Activation of NF-kappaB in B cells" }, { "id": "R-SSC-1234176", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1234176", "resource": "Reactome", "description": "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" }, { "id": "R-SSC-1236978", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1236978", "resource": "Reactome", "description": "Cross-presentation of soluble exogenous antigens (endosomes)" }, { "id": "R-SSC-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-SSC-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-SSC-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-SSC-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-SSC-187577", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-187577", "resource": "Reactome", "description": "SCF(Skp2)-mediated degradation of p27/p21" }, { "id": "R-SSC-202424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202424", "resource": "Reactome", "description": "Downstream TCR signaling" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2871837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2871837", "resource": "Reactome", "description": "FCERI mediated NF-kB activation" }, { "id": "R-SSC-349425", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-349425", "resource": "Reactome", "description": "Autodegradation of the E3 ubiquitin ligase COP1" }, { "id": "R-SSC-350562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-350562", "resource": "Reactome", "description": "Regulation of ornithine decarboxylase (ODC)" }, { "id": "R-SSC-382556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-382556", "resource": "Reactome", "description": "ABC-family protein mediated transport" }, { "id": "R-SSC-450408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450408", "resource": "Reactome", "description": "AUF1 (hnRNP D0) binds and destabilizes mRNA" }, { "id": "R-SSC-4608870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4608870", "resource": "Reactome", "description": "Asymmetric localization of PCP proteins" }, { "id": "R-SSC-4641257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4641257", "resource": "Reactome", "description": "Degradation of AXIN" }, { "id": "R-SSC-4641258", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4641258", "resource": "Reactome", "description": "Degradation of DVL" }, { "id": "R-SSC-5358346", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358346", "resource": "Reactome", "description": "Hedgehog ligand biogenesis" }, { "id": "R-SSC-5607761", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5607761", "resource": "Reactome", "description": "Dectin-1 mediated noncanonical NF-kB signaling" }, { "id": "R-SSC-5607764", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5607764", "resource": "Reactome", "description": "CLEC7A (Dectin-1) signaling" }, { "id": "R-SSC-5610780", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5610780", "resource": "Reactome", "description": "Degradation of GLI1 by the proteasome" }, { "id": "R-SSC-5610785", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5610785", "resource": "Reactome", "description": "GLI3 is processed to GLI3R by the proteasome" }, { "id": "R-SSC-5632684", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5632684", "resource": "Reactome", "description": "Hedgehog 'on' state" }, { "id": "R-SSC-5658442", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5658442", "resource": "Reactome", "description": "Regulation of RAS by GAPs" }, { "id": "R-SSC-5668541", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5668541", "resource": "Reactome", "description": "TNFR2 non-canonical NF-kB pathway" }, { "id": "R-SSC-5676590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5676590", "resource": "Reactome", "description": "NIK-->noncanonical NF-kB signaling" }, { "id": "R-SSC-5687128", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5687128", "resource": "Reactome", "description": "MAPK6/MAPK4 signaling" }, { "id": "R-SSC-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "resource": "Reactome", "description": "UCH proteinases" }, { "id": "R-SSC-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-SSC-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-SSC-68949", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68949", "resource": "Reactome", "description": "Orc1 removal from chromatin" }, { "id": "R-SSC-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-SSC-69481", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69481", "resource": "Reactome", "description": "G2/M Checkpoints" }, { "id": "R-SSC-69601", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69601", "resource": "Reactome", "description": "Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A" }, { "id": "R-SSC-75815", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75815", "resource": "Reactome", "description": "Ubiquitin-dependent degradation of Cyclin D" }, { "id": "R-SSC-8852276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8852276", "resource": "Reactome", "description": "The role of GTSE1 in G2/M progression after G2 checkpoint" }, { "id": "R-SSC-8854050", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854050", "resource": "Reactome", "description": "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" }, { "id": "R-SSC-8939236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939236", "resource": "Reactome", "description": "RUNX1 regulates transcription of genes involved in differentiation of HSCs" }, { "id": "R-SSC-8939902", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939902", "resource": "Reactome", "description": "Regulation of RUNX2 expression and activity" }, { "id": "R-SSC-8941858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8941858", "resource": "Reactome", "description": "Regulation of RUNX3 expression and activity" }, { "id": "R-SSC-8948751", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8948751", "resource": "Reactome", "description": "Regulation of PTEN stability and activity" }, { "id": "R-SSC-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-SSC-9020702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9020702", "resource": "Reactome", "description": "Interleukin-1 signaling" }, { "id": "R-SSC-9755511", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9755511", "resource": "Reactome", "description": "KEAP1-NFE2L2 pathway" }, { "id": "R-SSC-9766229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9766229", "resource": "Reactome", "description": "Degradation of CDH1" }, { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" }, { "id": "R-SSC-9907900", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9907900", "resource": "Reactome", "description": "Proteasome assembly" }, { "id": "R-SSC-9931269", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9931269", "resource": "Reactome", "description": "AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)" }, { "id": "R-SSC-9932298", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9932298", "resource": "Reactome", "description": "Degradation of CRY and PER proteins" }, { "id": "R-SSC-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" } ], "orthologs": [ { "uniprot_canonical_ac": "B0R1D0-1", "protein_name": "26S proteasome regulatory subunit 6B", "gene_name": "psmc4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDGGVLVEKPQDDVPALLNSRPQTGLSFLAPEPEDLEDLYSIYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVLYSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLVFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQEAGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK", "length": 418 }, "evidence": [ { "id": "A0A4X1SRU3", "url": "https://omabrowser.org/oma/group/A0A4X1SRU3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P33298-1", "protein_name": "26S proteasome regulatory subunit 6B homolog", "gene_name": "RPT3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEELGIVTPVEKAVEEKPAVKSYASLLAQLNGTVNNNSALSNVNSDIYFKLKKLEKEYELLTLQEDYIKDEQRHLKRELKRAQEEVKRIQSVPLVIGQFLEPIDQNTGIVSSTTGMSYVVRILSTLDRELLKPSMSVALHRHSNALVDILPPDSDSSISVMGENEKPDVTYADVGGLDMQKQEIREAVELPLVQADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAAFIRVNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDAQTGSDREVQRILIELLTQMDGFDQSTNVKVIMATNRADTLDPALLRPGRLDRKIEFPSLRDRRERRLIFGTIASKMSLAPEADLDSLIIRNDSLSGAVIAAIMQEAGLRAVRKNRYVILQSDLEEAYATQVKTDNTVDKFDFYK", "length": 428 }, "evidence": [ { "id": "A0A4X1SRU3", "url": "https://omabrowser.org/oma/group/A0A4X1SRU3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P34123-1", "protein_name": "26S proteasome regulatory subunit 6B homolog", "gene_name": "psmC4", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEELGLATAKVTVTKEASHHREADLYQKMKSLESKLDFFNIQEEYIKYEYKNLKRELLHAQEEVKRIRSVPLLIGQLLEMVDSNTGIVQSTSGSTLCVRILSTIDRELLKPSASVALQRHSNALVDTLPPESDSSIHLLGADEKPSESYSDIGGGDIQKQEMREAVELPLTHHNLYKQIGIDPPRGVLLYGPPGTGKTMLAKAVAHHTSAAFIRVVGSEFVQKYLGEGPRLVRDVFRLARENSPAIIFIDEIDAIATKRFDAQTGADREVQRILMELLNQMDGFDVSVNVKVIMATNRQDTLDPALLRPGRLDRKIEFPLPDRRQKRLIFQVITSKMNLSDEVDLEDYVSRPDKLSGAEIQSICQEAGMHAIRKNRYVILPKDFEKGYKASIKKNTHEFNFYN", "length": 403 }, "evidence": [ { "id": "A0A4X1SRU3", "url": "https://omabrowser.org/oma/group/A0A4X1SRU3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P43686-1", "protein_name": "26S proteasome regulatory subunit 6B", "gene_name": "PSMC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK", "length": 418 }, "evidence": [ { "id": "A0A4X1SRU3", "url": "https://omabrowser.org/oma/group/A0A4X1SRU3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54775-1", "protein_name": "26S proteasome regulatory subunit 6B", "gene_name": "Psmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEIGILVEKIQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK", "length": 418 }, "evidence": [ { "id": "A0A4X1SRU3", "url": "https://omabrowser.org/oma/group/A0A4X1SRU3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3T030-1", "protein_name": "26S proteasome regulatory subunit 6B", "gene_name": "PSMC4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK", "length": 418 }, "evidence": [ { "id": "A0A4X1SRU3", "url": "https://omabrowser.org/oma/group/A0A4X1SRU3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q63570-1", "protein_name": "26S proteasome regulatory subunit 6B", "gene_name": "Psmc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEIGILVEKIQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK", "length": 418 }, "evidence": [ { "id": "A0A4X1SRU3", "url": "https://omabrowser.org/oma/group/A0A4X1SRU3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9SEI4-1", "protein_name": "26S proteasome regulatory subunit 6B homolog", "gene_name": "RPT3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASAAVASMVLDPKASPALMDLSTADEEDLYGRLKSLERQLEFTDIQEEYVKDEQKNLKRELLRAQEEVKRIQSVPLVIGQFMEMVDQNNGIVGSTTGSNYYVRILSTINRELLKPSASVALHRHSNALVDVLPPEADSSISLLSQSEKPDVSYNDIGGCDIQKQEIREAVELPLTHHELYKQIGIDPPRGVLLYGPPGTGKTMLAKAVANHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEVDAIATARFDAQTGADREVQRILMELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLVFQVCTSKMNLSDEVDLEDYVSRPDKISAAEIAAICQEAGMHAVRKNRYVILPKDFEKGYRANVKKPDTDFEFYK", "length": 408 }, "evidence": [ { "id": "A0A4X1SRU3", "url": "https://omabrowser.org/oma/group/A0A4X1SRU3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V405-1", "protein_name": "26S proteasome regulatory subunit 6B", "gene_name": "Rpt3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPYNMDVLIPEKDELSDLKLKDAHSSLDELDMEDLYVRYKKLQKTLEFIEVQEEYIKDEQRNLKKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKHSNALVDVLPPEADSSISMLQPDEKPDVSYADIGGMDMQKQEIREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLVFSTITSKMNLSEDVDLEEFVARPDKISGADINAICQEAGMHAVRENRYIVLAKDFEKGYKNNIKKDEQEHEFYK", "length": 413 }, "evidence": [ { "id": "A0A4X1SRU3", "url": "https://omabrowser.org/oma/group/A0A4X1SRU3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "proteasome regulatory particle, base subcomplex", "id": "GO:0008540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008540", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRU3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRU3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRU3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRU3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRU3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3" } ], "pmid": "" }, { "name": "proteasome-activating activity", "id": "GO:0036402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036402", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRU3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SRU3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SRU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRU3" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 198, "end_pos": 337, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 353, "end_pos": 355 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SS99-1", "uniprot_ac": "A0A4X1SS99", "uniprot_id": "A0A4X1SS99_PIG", "mass": { "chemical_mass": 32679.0, "monoisotopic_mass": 32679.0 }, "refseq": { "ac": "NP_001230839", "name": "mitochondrial ornithine transporter 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230839" }, "gene_names": [ { "name": "SLC25A15", "type": "recommended", "evidence": [ { "id": "A0A4X1SS99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99" } ] }, { "name": "SLC25A15", "type": "synonym", "evidence": [ { "id": "NP_001230839", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230839" } ] } ], "protein_names": [ { "name": "Mitochondrial ornithine transporter 1", "type": "recommended", "evidence": [ { "id": "A0A4X1SS99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 25 member 15", "type": "synonym", "evidence": [ { "id": "A0A4X1SS99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial ornithine transporter 1", "type": "synonym", "evidence": [ { "id": "NP_001230839", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230839" } ] }, { "name": "ornithine transporter) member 15", "type": "synonym", "evidence": [ { "id": "NP_001230839", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230839" } ] }, { "name": "solute carrier family 25 (mitochondrial carrier", "type": "synonym", "evidence": [ { "id": "NP_001230839", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230839" } ] } ], "function": [ { "annotation": "Mitochondrial ornithine-citrulline antiporter. Catalyzes the exchange between cytosolic ornithine and mitochondrial citrulline plus an H(+), the proton compensates the positive charge of ornithine thus leading to an electroneutral transport. Plays a crucial role in the urea cycle, by connecting the cytosolic and the intramitochondrial reactions of the urea cycle. Lysine and arginine are also transported by the antiport mechanism. In addition, catalyzes an electroneutral exchange of ornithine or lysine for H(+), a reaction driven by the pH gradient across the inner membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SS99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99#function" }, { "database": "UniProtKB", "id": "ARBA00054811", "url": "https://www.uniprot.org/uniprotkb/ARBA00054811#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SS99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC25A15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99", "locus": { "chromosome": "11", "start_pos": 15559312, "end_pos": 15494385, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009373", "url": "https://www.ensembl.org/id/ENSSSCG00000009373" } ] } } ], "crossref": [ { "id": "A0A4X1SS99", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SS99", "database": "AlphaFoldDB", "categories": [] }, { "id": "100511895", "url": "https://www.ncbi.nlm.nih.gov/gene/100511895", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511895", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511895", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PIDCFRQ", "url": "https://omabrowser.org/oma/group/PIDCFRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SS99", "url": "https://www.orthodb.org/?gene=A0A4X1SS99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-70635", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70635", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230839", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230839", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "34991", "url": "https://www.rhea-db.org/rhea/34991", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70787", "url": "https://www.rhea-db.org/rhea/70787", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70791", "url": "https://www.rhea-db.org/rhea/70791", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70795", "url": "https://www.rhea-db.org/rhea/70795", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70799", "url": "https://www.rhea-db.org/rhea/70799", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SS99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SS99-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDRQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVVKSILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIGTFISVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMSQFEAY", "length": 301, "header": "tr|A0A4X1SS99-1|A0A4X1SS99_PIG Isoform 1 of Mitochondrial ornithine transporter 1 OS=Sus scrofa OX=9823 GN=SLC25A15 PE=3 SV=1 CANONICAL=A0A4X1SS99-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SS99-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99/entry#A0A4X1SS99-1", "sequence": { "sequence": "MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDRQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVVKSILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIGTFISVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMSQFEAY", "length": 301, "header": "tr|A0A4X1SS99-1|A0A4X1SS99_PIG Isoform 1 of Mitochondrial ornithine transporter 1 OS=Sus scrofa OX=9823 GN=SLC25A15 PE=3 SV=1 CANONICAL=A0A4X1SS99-1" }, "locus": { "chromosome": "11", "start_pos": 15545569, "end_pos": 15497347, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049064.2", "url": "https://www.ensembl.org/id/ENSSSCT00000049064.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053420.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053420.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SS99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511895", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511895", "resource": "KEGG Pathway" }, { "id": "R-SSC-70635", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70635", "resource": "Reactome", "description": "Urea cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IJE3-1", "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "Slc25a15", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKMVGLDRQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMESSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGKSKDELGPVPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMNQLEAY", "length": 301 }, "evidence": [ { "id": "A0A4X1SS99", "url": "https://omabrowser.org/oma/group/A0A4X1SS99/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A0G2K309-1", "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "Slc25a15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLRTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVVGLDRQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPIPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLIRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMSQLEAC", "length": 301 }, "evidence": [ { "id": "A0A4X1SS99", "url": "https://omabrowser.org/oma/group/A0A4X1SS99/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12375-1", "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "ORT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEDSKKKGLIEGAILDIINGSIAGACGKVIEFPFDTVKVRLQTQASNVFPTTWSCIKFTYQNEGIARGFFQGIASPLVGACLENATLFVSYNQCSKFLEKHTNVSPLGQILISGGVAGSCASLVLTPVELVKCKLQVANLQVASAKTKHTKVLPTIKAIITERGLAGLWQGQSGTFIRESFGGVAWFATYEIVKKSLKDRHSLDDPKRDESKIWELLISGGSAGLAFNASIFPADTVKSVMQTEHISLTNAVKKIFGKFGLKGFYRGLGITLFRAVPANAAVFYIFETLSAL", "length": 292 }, "evidence": [ { "id": "A0A4X1SS99", "url": "https://omabrowser.org/oma/group/A0A4X1SS99/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7KVQ8-1", "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "Dmel\\CG1628", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSECEQDTASAAAPTSNHNEDGDNEEAGSEAAEFVSLPPPLEPEPIKQRHPKSQPTDEAPPEPPPNEDEMPPPPPRIGSSQAGSSVLIMTPDEIIEAYERALQEGQEEDGETDGEKKKSGWLNRPISVKSTLRAVRDGLLFVVGGFLRFVRRLDMHGGGTGNNINFVEGLIDFLAGSLGGAAQVYVSQPLDTVKVKLQTFPEAYRGMLDCFLSTYRKDGVLRGLYAGSVPAVFANVAENSVLFAAYGGCQKFVAFCVGKETAGDLTTVQNACAGSLAACFSTLTLCPTELIKCKLQALREMKNFVEPAHPQDIRTPWTLTRYIWRTEGIRGFYRGLSSTFLREMPGYFFFFGSYEGTRELLRRDDQSKDDIGPLRTMIAGAIGGVCLWTSTFPADVIKSRIQVKNLNESMFAVGADIVRREGVLALYRGLLPSVLRTIPATATLFVVYEYTKRALSATL", "length": 459 }, "evidence": [ { "id": "A0A4X1SS99", "url": "https://omabrowser.org/oma/group/A0A4X1SS99/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q84UC7-1", "protein_name": "Mitochondrial arginine transporter BAC1", "gene_name": "BAC1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGESKTTTGEGFGFYKEYVAGMMAGLATVAVGHPFDTVKVKLQKHNTDVQGLRYKNGLHCASRILQTEGVKGLYRGATSSFMGMAFESSLMFGIYSQAKLFLRGTLPDDGPRPEIIVPSAMFGGAIISFVLCPTELVKCRMQIQGTDSLVPNFRRYNSPLDCAVQTVKNDGVTGIFRGGSATLLRECTGNAVFFTVYEYLRYHIHSRLEDSKLKDGYLVDMGIGVLTGGLGGIACWSAVLPFDVAKTIIQTSSEKATERNPFKVLSSIHKRAGLKGCYAGLGPTIVRAFPANAAAIVAWEFSMKMLGIKRD", "length": 311 }, "evidence": [ { "id": "A0A4X1SS99", "url": "https://omabrowser.org/oma/group/A0A4X1SS99/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9WVD5-1", "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "Slc25a15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVVGLDQQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMNQLEAW", "length": 301 }, "evidence": [ { "id": "A0A4X1SS99", "url": "https://omabrowser.org/oma/group/A0A4X1SS99/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y619-1", "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "SLC25A15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMNQLEAY", "length": 301 }, "evidence": [ { "id": "A0A4X1SS99", "url": "https://omabrowser.org/oma/group/A0A4X1SS99/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "L-ornithine transmembrane transporter activity", "id": "GO:0000064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000064", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SS99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SS99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99" } ], "pmid": "" }, { "name": "L-lysine transmembrane transporter activity", "id": "GO:0015189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015189", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SS99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99" } ], "pmid": "" }, { "name": "L-arginine transmembrane transporter activity", "id": "GO:0061459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061459", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SS99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SS99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SS99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial L-ornithine transmembrane transport", "id": "GO:1990575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990575", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SS99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SS99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "34991", "name": "", "equation": "L-ornithine(in) + L-arginine(out) = L-ornithine(out) + L-arginine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34991", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34991" } ] }, { "id": "70787", "name": "", "equation": "L-citrulline(in) + L-ornithine(out) + H(+)(in) = L-citrulline(out) + L-ornithine(in) + H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70787", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70787" } ] }, { "id": "70791", "name": "", "equation": "L-ornithine(out) + H(+)(in) = L-ornithine(in) + H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70791", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70791" } ] }, { "id": "70795", "name": "", "equation": "L-lysine(out) + H(+)(in) = L-lysine(in) + H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70795", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70795" } ] }, { "id": "70799", "name": "", "equation": "L-ornithine(out) + L-lysine(in) = L-ornithine(in) + L-lysine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70799", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70799" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SSR7-1", "uniprot_ac": "A0A4X1SSR7", "uniprot_id": "A0A4X1SSR7_PIG", "mass": { "chemical_mass": 11629.0, "monoisotopic_mass": 11629.0 }, "refseq": { "ac": "XP_020924398", "name": "T-cell leukemia translocation-altered gene protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924398" }, "gene_names": [ { "name": "TCTA", "type": "recommended", "evidence": [ { "id": "A0A4X1SSR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSR7" } ] }, { "name": "TCTA", "type": "synonym", "evidence": [ { "id": "XP_020924398", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924398" } ] } ], "protein_names": [ { "name": "T-cell leukemia translocation-altered gene protein homolog", "type": "recommended", "evidence": [ { "id": "A0A4X1SSR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSR7/entry#names_and_taxonomy" } ] }, { "name": "T-cell leukemia translocation-altered gene protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020924398", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924398" } ] } ], "function": [ { "annotation": "May be required for cellular fusion during osteoclastogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SSR7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSR7#function" }, { "database": "UniProtKB", "id": "PIRNR009935", "url": "https://www.uniprot.org/uniprotkb/PIRNR009935#function" }, { "database": "UniProtKB", "id": "ARBA00003045", "url": "https://www.uniprot.org/uniprotkb/ARBA00003045#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SSR7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSR7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TCTA", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSR7", "locus": { "chromosome": "13", "start_pos": 31998129, "end_pos": 31991610, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037459", "url": "https://www.ensembl.org/id/ENSSSCG00000037459" } ] } } ], "crossref": [ { "id": "A0A4X1SSR7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SSR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "110256231", "url": "https://www.ncbi.nlm.nih.gov/gene/110256231", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SMWESTS", "url": "https://omabrowser.org/oma/group/SMWESTS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR32267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32267:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32267:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15128", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15128", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020924398", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924398", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SSR7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SSR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPWSGQSLQVLPATVLGALGALGSEFLREWEAQDMRVTLFKLLLLWLVLSLLSIQLAWGFYGSTVTGLYHRPGLGSQNGSTPDGSTHFSSWETAANEPLKTHRE", "length": 106, "header": "tr|A0A4X1SSR7-1|A0A4X1SSR7_PIG Isoform 1 of T-cell leukemia translocation-altered gene protein homolog OS=Sus scrofa OX=9823 GN=TCTA PE=3 SV=1 CANONICAL=A0A4X1SSR7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SSR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSR7/entry#A0A4X1SSR7-1", "sequence": { "sequence": "MAEPWSGQSLQVLPATVLGALGALGSEFLREWEAQDMRVTLFKLLLLWLVLSLLSIQLAWGFYGSTVTGLYHRPGLGSQNGSTPDGSTHFSSWETAANEPLKTHRE", "length": 106, "header": "tr|A0A4X1SSR7-1|A0A4X1SSR7_PIG Isoform 1 of T-cell leukemia translocation-altered gene protein homolog OS=Sus scrofa OX=9823 GN=TCTA PE=3 SV=1 CANONICAL=A0A4X1SSR7-1" }, "locus": { "chromosome": "13", "start_pos": 31993949, "end_pos": 31991613, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043143.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043143.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044269.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044269.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SSR7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSR7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G1H1-1", "protein_name": "T-cell leukemia translocation-altered gene protein isoform X1", "gene_name": "Tcta", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEPWSGQFLQALPASVLGALGTLGSEFLREWETQDMRVTLFKLLLLWLVLSLLGIQLAWGFYGNTVTGLYHRPGKWQQMNLSKPTENKGRQQQKRLQRHNWDCWLLGCILLLPRPVGQLQRAWGWGTGVPQCFQGEPPLLSALPSTAPGTGQVKSVSTPV", "length": 161 }, "evidence": [ { "id": "A0A4X1SSR7", "url": "https://omabrowser.org/oma/group/A0A4X1SSR7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P57738-1", "protein_name": "T-cell leukemia translocation-altered gene protein", "gene_name": "TCTA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESWSGQALQALPATVLGALGSEFLREWEAQDMRVTLFKLLLLWLVLSLLGIQLAWGFYGNTVTGLYHRPGLGGQNGSTPDGSTHFPSWEMAANEPLKTHRE", "length": 103 }, "evidence": [ { "id": "A0A4X1SSR7", "url": "https://omabrowser.org/oma/group/A0A4X1SSR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5EAA5-1", "protein_name": "T-cell leukemia translocation-altered gene protein homolog", "gene_name": "TCTA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEPWSGQSLQALPATVLGALGALGSEFLREWEAQDMRVTLFKLLLFWLVLSLLSIQLAWGFYGSTVTGLYHRPGLGGQNGSTPDGSTHFPSWETAANEPLKTHRE", "length": 106 }, "evidence": [ { "id": "A0A4X1SSR7", "url": "https://omabrowser.org/oma/group/A0A4X1SSR7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6DGY3-1", "protein_name": "T-cell leukemia translocation-altered gene protein homolog", "gene_name": "tcta", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEESWDFEFLSRMVDSLVSFLSEFVDDWLANDMRVAVFKILFSWLVVSLVAIHFAWKVYGNTVNDMYYRQGTGGQNGGTPDTHLSGWESAAGDAMKTHRE", "length": 100 }, "evidence": [ { "id": "A0A4X1SSR7", "url": "https://omabrowser.org/oma/group/A0A4X1SSR7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8VEA7-1", "protein_name": "T-cell leukemia translocation-altered gene protein homolog", "gene_name": "Tcta", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEPWAGQFLQALPATVLGALGTLGSDFLREWETQDMRVTLFKLLLLWLVLSLLGIQLAWGFYGNTVTGLYHRPDPHPQPPAAMGVFLPPGLGGQNGSTPDGSTHFSSWEIAANEALKTHRE", "length": 122 }, "evidence": [ { "id": "A0A4X1SSR7", "url": "https://omabrowser.org/oma/group/A0A4X1SSR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SSR7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of osteoclast differentiation", "id": "GO:0045671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045671", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SSR7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSR7" } ], "pmid": "" }, { "name": "osteoclast fusion", "id": "GO:0072675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072675", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SSR7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SSR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1ST50-1", "uniprot_ac": "A0A4X1ST50", "uniprot_id": "A0A4X1ST50_PIG", "mass": { "chemical_mass": 35718.0, "monoisotopic_mass": 35718.0 }, "refseq": {}, "gene_names": [ { "name": "KCTD10", "type": "recommended", "evidence": [ { "id": "A0A4X1ST50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50" } ] } ], "protein_names": [ { "name": "Potassium channel tetramerization domain containing 10", "type": "synonym", "evidence": [ { "id": "A0A4X1ST50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST50", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KCTD10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50", "locus": { "chromosome": "14", "start_pos": 41470209, "end_pos": 41442777, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009934", "url": "https://www.ensembl.org/id/ENSSSCG00000009934" } ] } } ], "crossref": [ { "id": "A0A4X1ST50", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1ST50", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18399", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18399", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11145", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11145", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11145:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11145:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1ST50", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1ST50-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERERIERVRRIHIKRPDDRAHLHQ", "length": 315, "header": "tr|A0A4X1ST50-1|A0A4X1ST50_PIG Isoform 1 of Potassium channel tetramerization domain containing 10 OS=Sus scrofa OX=9823 GN=KCTD10 PE=3 SV=1 CANONICAL=A0A4X1ST50-1" }, "isoforms": [ { "isoform_ac": "A0A4X1ST50-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50/entry#A0A4X1ST50-1", "sequence": { "sequence": "MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERERIERVRRIHIKRPDDRAHLHQ", "length": 315, "header": "tr|A0A4X1ST50-1|A0A4X1ST50_PIG Isoform 1 of Potassium channel tetramerization domain containing 10 OS=Sus scrofa OX=9823 GN=KCTD10 PE=3 SV=1 CANONICAL=A0A4X1ST50-1" }, "locus": { "chromosome": "14", "start_pos": 41467428, "end_pos": 41442859, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010886.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010886.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010601.4", "url": "https://www.ensembl.org/id/ENSSSCP00000010601.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST50", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST50", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST50", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST50", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50" } ], "pmid": "" }, { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST50", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST50", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST50", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST50", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50" } ], "pmid": "" }, { "name": "negative regulation of Rho protein signal transduction", "id": "GO:0035024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035024", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ST50", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1ST50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ST50" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 100, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1STB8-1", "uniprot_ac": "A0A4X1STB8", "uniprot_id": "A0A4X1STB8_PIG", "mass": { "chemical_mass": 47516.0, "monoisotopic_mass": 47516.0 }, "refseq": { "ac": "XP_005653765", "name": "transmembrane protease serine 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653765" }, "gene_names": [ { "name": "TMPRSS4", "type": "recommended", "evidence": [ { "id": "A0A4X1STB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8" } ] }, { "name": "TMPRSS4", "type": "synonym", "evidence": [ { "id": "XP_005653765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653765" } ] } ], "protein_names": [ { "name": "Transmembrane serine protease 4", "type": "synonym", "evidence": [ { "id": "A0A4X1STB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protease serine 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005653765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653765" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STB8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMPRSS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8", "locus": { "chromosome": "9", "start_pos": 45435916, "end_pos": 45400600, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015086", "url": "https://www.ensembl.org/id/ENSSSCG00000015086" } ] } } ], "crossref": [ { "id": "A0A4X1STB8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1STB8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100514419", "url": "https://www.ncbi.nlm.nih.gov/gene/100514419", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514419", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514419", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GNWASAC", "url": "https://omabrowser.org/oma/group/GNWASAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1STB8", "url": "https://www.orthodb.org/?gene=A0A4X1STB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15494", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15494", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005653765", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653765", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1STB8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1STB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPASDQPLNSLDVAPQRKPRTPLQTFKKVGIPIIAALLGLAAIVVVAILIKVILDKYYFLCWQPLHFIPREQLCDGQQDCASGEDEQLCVKKFPDGPPVAVRLSRDRSTLQVLHPATQTWASACFDNFTEALAKTACGQMGYDSKPTFRAVRIGPDQDLDVVKITENDQELRVQNSSGPCLSGSLVSLHCLACGESLKAPRVVGGEKASVDSWPWQVSIQYNKQHICGGSILDPHWILTAAHCFWKHLDVPNWKVRAGSDKLGNFPSLPVAKIFITEPNSTSPKEKDIALVKLQLPLTFSGTVRPICLPFSDEELTPGTPVWVIGWGFTEPNGGKMSDHLLQASVQVINRTRCNAEDAYQGEVTEKMLCAGLLEGGVDTCQGDSGGPLMYHSGRWQAVGIVSWGYGCGGPSTPGVYTKVTAYLDWIYNVRKSDP", "length": 435, "header": "tr|A0A4X1STB8-1|A0A4X1STB8_PIG Isoform 1 of Transmembrane serine protease 4 OS=Sus scrofa OX=9823 GN=TMPRSS4 PE=4 SV=1 CANONICAL=A0A4X1STB8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1STB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8/entry#A0A4X1STB8-1", "sequence": { "sequence": "MDPASDQPLNSLDVAPQRKPRTPLQTFKKVGIPIIAALLGLAAIVVVAILIKVILDKYYFLCWQPLHFIPREQLCDGQQDCASGEDEQLCVKKFPDGPPVAVRLSRDRSTLQVLHPATQTWASACFDNFTEALAKTACGQMGYDSKPTFRAVRIGPDQDLDVVKITENDQELRVQNSSGPCLSGSLVSLHCLACGESLKAPRVVGGEKASVDSWPWQVSIQYNKQHICGGSILDPHWILTAAHCFWKHLDVPNWKVRAGSDKLGNFPSLPVAKIFITEPNSTSPKEKDIALVKLQLPLTFSGTVRPICLPFSDEELTPGTPVWVIGWGFTEPNGGKMSDHLLQASVQVINRTRCNAEDAYQGEVTEKMLCAGLLEGGVDTCQGDSGGPLMYHSGRWQAVGIVSWGYGCGGPSTPGVYTKVTAYLDWIYNVRKSDP", "length": 435, "header": "tr|A0A4X1STB8-1|A0A4X1STB8_PIG Isoform 1 of Transmembrane serine protease 4 OS=Sus scrofa OX=9823 GN=TMPRSS4 PE=4 SV=1 CANONICAL=A0A4X1STB8-1" }, "locus": { "chromosome": "9", "start_pos": 45434538, "end_pos": 45400830, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040038.2", "url": "https://www.ensembl.org/id/ENSSSCT00000040038.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053385.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053385.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 413, "start_aa": "Thr", "end_pos": 413, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr413", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STB8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514419", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514419", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZX70-1", "protein_name": "Transmembrane serine protease 4", "gene_name": "TMPRSS4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDPASERLNGEEPGTRHKASGAQHSWKRIGIPILVTVLVLACLAAVGLLVKVYLEHHYFICKQPLKLVPLAQVCNGEADCLHGEDETSCPQQVPEGPQAAARLSKDRSILQVLNRNTGAWSCVCSDYFSPALAKAACEEMGYSSTPTFHAVDAGAGQPLPPRELVLSNGRLQLPEPGRKCLSGSVVSLLCSSCGESVRTPRVLGGRPAAIEAWPWQVSLRYRGEHICGGSIIDPLWILTAAHCFRNNPIIPSWRVKAGSDVLSGPANLAVEKVFLAEGTPTSPNNNDIALVKLQIPLHISDSTKPICLPYFDEELEPDTPLWVIGWGYTQQNGKLSEALQQAEVRLISMQSCNLQAYHGKVTQKMLCAGLLEGGVDTCQVRGSTGCPTTLGVPAPELGQVVLWNGPVEGMRARRDAHSQRWSLAGGQRRASAVCKQALAGGGHRQLGLRLRHPQHTRCLHQRPSVPRLDLRRPQVGALRPARTSVLCQRPDEEAKGGSGSGHSLGMHPAGAPFQREINLLPCADPAVSGSTLLFAHYCFTEINDVCALVYRL", "length": 552 }, "evidence": [ { "id": "A0A4X1STB8", "url": "https://omabrowser.org/oma/group/A0A4X1STB8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3Z9X4-1", "protein_name": "Transmembrane protease serine 4", "gene_name": "Tmprss4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPDSGQPLNNHDVPPFRKPRSPLETFKKVGIPIIAVILSLIALGIVALLIKVVLDKYYFICGNPLTFIPRGQMCDGHLDCASGEDEEHCVKNFPEKPGVTVRLSKDRSTLQVLDAARGTWASVCFDNFTEALAKTACRQMGYNSQPAFGPVEMGPNQTLLVTPVTGNSQELQMQNGSRSCLSGSLVSLRCLDCGKSLKTTRVVGGVEASADSWPWQVSIQYNKQHVCGGSILDHHWILTAAHCFRKYLDVSSWKVRAGSNKLGNSPSLPVAKIFIAEPNPLQPKEKDIALVKLKMPLTFSGSVRPICLPFSDEELIPTMPVWVIGWGFTEENGGKMSDTLLQASVQVIDSARCNAEDAYQGEVTAGMLCAGTPQGGKDTCQGDSGGPLMYHYDKWQVVGIVSWGYGCGSPSTPGVYTKVTAYLDWIYNVRRSEM", "length": 435 }, "evidence": [ { "id": "A0A4X1STB8", "url": "https://omabrowser.org/oma/group/A0A4X1STB8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6PZT6-1", "protein_name": "Transmembrane serine protease 4", "gene_name": "TMPRSS4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MENSEDRRARVDPEINRPLNSLDVTPLRKSRTPLEIFKKVGIPIIAAVLILATIIVVAVLIKVILDSYFFFCGQPLLFIPREQVCDGHQDCASGEDEKYCVKKLPDGPPVAVRLSRDRSTLQVLNPATKNWASACFDSFTEALAKTACRQMGYDSSKPTFRAVDAGPAQDLDIVKVTENLQELQVQNSSGPCLSGSLVSLQCLACGQSVKAPRVVGGKEASVDSWPWQVSIQYDKQHICGGSILDPHWILTAAHCFWKHLDVPNWKVRAGSDRLGSFPSLPVAKIFILEPNATYPREHDIALVKLQLPLTFSGTIRPICLPFSDEELTPGTPLWVIGWGFTEENGGKMSDILQQGSVQLINRTRCNAEDAYQGEVTKTMMCAGLPEGGVDTCQGDSGGPLMYHSDWWQVVGIVSWGHGCGGPTTPGVYTKVTAYLNWIYNVRKSDP", "length": 446 }, "evidence": [ { "id": "A0A4X1STB8", "url": "https://omabrowser.org/oma/group/A0A4X1STB8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VCA5-1", "protein_name": "Transmembrane protease serine 4", "gene_name": "Tmprss4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESDSGQPLNNRDIVPFRKPRRPQETFKKVGIPIIAVLLSLIALVIVALLIKVILDKYYFICGSPLTFIQRGQLCDGHLDCASGEDEEHCVKDFPEKPGVAVRLSKDRSTLQVLDAATGTWASVCFDNFTEALAKTACRQMGYDSQPAFRAVEIRPDQNLPVAQVTGNSQELQVQNGSRSCLSGSLVSLRCLDCGKSLKTPRVVGGVEAPVDSWPWQVSIQYNKQHVCGGSILDPHWILTAAHCFRKYLDVSSWKVRAGSNILGNSPSLPVAKIFIAEPNPLYPKEKDIALVKLQMPLTFSGSVRPICLPFSDEVLVPATPVWVIGWGFTEENGGKMSDMLLQASVQVIDSTRCNAEDAYEGEVTAEMLCAGTPQGGKDTCQGDSGGPLMYHSDKWQVVGIVSWGHGCGGPSTPGVYTKVTAYLNWIYNVRKSEM", "length": 435 }, "evidence": [ { "id": "A0A4X1STB8", "url": "https://omabrowser.org/oma/group/A0A4X1STB8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRS4-1", "protein_name": "Transmembrane protease serine 4", "gene_name": "TMPRSS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKYYFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVWKAEL", "length": 437 }, "evidence": [ { "id": "A0A4X1STB8", "url": "https://omabrowser.org/oma/group/A0A4X1STB8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STB8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STB8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STB8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STB8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STB8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STB8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8" } ], "pmid": "" }, { "name": "positive regulation of viral entry into host cell", "id": "GO:0046598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046598", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STB8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1STB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 432, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1STB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STB8" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 142, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 413 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 176, "end_pos": 178 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 350, "end_pos": 352 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1STL2-1", "uniprot_ac": "A0A4X1STL2", "uniprot_id": "A0A4X1STL2_PIG", "mass": { "chemical_mass": 22486.0, "monoisotopic_mass": 22486.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "type": "recommended", "evidence": [ { "id": "A0A4X1STL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "A0A4X1STL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2/entry#names_and_taxonomy" } ] }, { "name": "CTD phosphatase SSU72", "type": "synonym", "evidence": [ { "id": "A0A4X1STL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2#function" }, { "database": "UniProtKB", "id": "RU369031", "url": "https://www.uniprot.org/uniprotkb/RU369031#function" }, { "database": "UniProtKB", "id": "ARBA00034669", "url": "https://www.uniprot.org/uniprotkb/ARBA00034669#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2", "locus": {} } ], "crossref": [ { "id": "A0A4X1STL2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1STL2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR006811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036196", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036196", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RPMFAMV", "url": "https://omabrowser.org/oma/group/RPMFAMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR20383", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20383", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1STL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1STL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSLPLRVAVVCSSNQNRSMEAHSILSKRGFSVRSFGTGAHVKLPGPAPDKPNVYDFRTTYDQMYNDLLMKDKDLYTQNGILHMLDRNKRIKPRPERFQNCKDPFDLIITCEERVYDLVVEDLNSREQETCQPVHVINVDIQDNHEEATLGAFLICELCQCIQHTEDVDNEIEELLQEFEEKSGQTFLHTVCFY", "length": 194, "header": "tr|A0A4X1STL2-1|A0A4X1STL2_PIG Isoform 1 of RNA polymerase II subunit A C-terminal domain phosphatase SSU72 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1STL2-1" }, "isoforms": [ { "isoform_ac": "A0A4X1STL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2/entry#A0A4X1STL2-1", "sequence": { "sequence": "MQSLPLRVAVVCSSNQNRSMEAHSILSKRGFSVRSFGTGAHVKLPGPAPDKPNVYDFRTTYDQMYNDLLMKDKDLYTQNGILHMLDRNKRIKPRPERFQNCKDPFDLIITCEERVYDLVVEDLNSREQETCQPVHVINVDIQDNHEEATLGAFLICELCQCIQHTEDVDNEIEELLQEFEEKSGQTFLHTVCFY", "length": 194, "header": "tr|A0A4X1STL2-1|A0A4X1STL2_PIG Isoform 1 of RNA polymerase II subunit A C-terminal domain phosphatase SSU72 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1STL2-1" }, "locus": { "chromosome": "X", "start_pos": 117065556, "end_pos": 117064975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013907.3", "url": "https://www.ensembl.org/id/ENSSSCT00000013907.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042891.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042891.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "termination of RNA polymerase II transcription", "id": "GO:0006369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006369", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA polymerase II CTD heptapeptide repeat phosphatase activity", "id": "GO:0008420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008420", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 17, "end_pos": 19 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SUV4-1", "uniprot_ac": "A0A4X1SUV4", "uniprot_id": "A0A4X1SUV4_PIG", "mass": { "chemical_mass": 83753.0, "monoisotopic_mass": 83753.0 }, "refseq": {}, "gene_names": [ { "name": "PNN", "type": "recommended", "evidence": [ { "id": "A0A4X1SUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" } ] } ], "protein_names": [ { "name": "Pinin", "type": "recommended", "evidence": [ { "id": "A0A4X1SUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUV4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PNN", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4", "locus": { "chromosome": "1", "start_pos": 169734003, "end_pos": 169725649, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000022828", "url": "https://www.ensembl.org/id/ENSSSCG00000022828" } ] } } ], "crossref": [ { "id": "A0A4X1SUV4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SUV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100526149", "url": "https://www.ncbi.nlm.nih.gov/gene/100526149", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100526149", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100526149", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SUU5", "url": "https://www.orthodb.org/?gene=A0A4X1SUU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12707", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12707", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12707:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12707:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04696", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04696", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1STL7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1STL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SUU5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SUU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SUV4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SUV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SUY2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SUY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SV98", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SV98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SV98-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SV98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKRPALQSSVVATSKERTRRDLIQDQNMDEKGKQRKFKELNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKSEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIGIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVESVKNVIAEQEVMETNQVESIEPSENETSKELEPEMEFEVEPDKECKSLSPAKENSSALEMENEPEEKEEKESEPQPEPMSQPQPLPQPQPQSQPQPQPQAQTQAQCQSQSQPALQPQPLSQPETMPLAVLQPPPQAIQEQGHLPPERKEFPVESAKLTEVTVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTTSSSESRSRSRGRGHNRDRKHRRSVDRKRRDASGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR", "length": 736, "header": "tr|A0A4X1SUV4-1|A0A4X1SUV4_PIG Isoform 1 of Pinin OS=Sus scrofa OX=9823 GN=PNN PE=1 SV=1 CANONICAL=A0A4X1SUV4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1STL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4/entry#A0A4X1STL7-1", "sequence": { "sequence": "MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKRVLRLKELHRG", "length": 119, "header": "tr|A0A4X1STL7-1|A0A4X1STL7_PIG Computationally mapped isoform of Pinin, desmosome associated protein OS=Sus scrofa OX=9823 GN=PNN PE=4 SV=1 CANONICAL=A0A4X1SUV4-1" }, "locus": { "chromosome": "1", "start_pos": 169728418, "end_pos": 169725726, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104195.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104195.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077117.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077117.1" } ] } }, { "isoform_ac": "A0A4X1SUU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4/entry#A0A4X1SUU5-1", "sequence": { "sequence": "MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKRPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKSEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIGIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVESVKNVIAEQEVMETNQVESIEPSENETSKELEPEMEFEVEPDKECKSLSPAKENSSALEMENEPEEKEEKESEPQPEPMSQPQPLPQPQPQSQPQPQPQAQTQAQCQSQSQPALQPQPLSQPETMPLAVLQPPPQAIQEQGHLPPERKEFPVESAKLTEVTVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTTSSSESRSRSRGRGHNRDRKHRRSVDRKRRDASGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR", "length": 731, "header": "tr|A0A4X1SUU5-1|A0A4X1SUU5_PIG Computationally mapped isoform of Pinin OS=Sus scrofa OX=9823 GN=PNN PE=1 SV=1 CANONICAL=A0A4X1SUV4-1" }, "locus": { "chromosome": "1", "start_pos": 169732907, "end_pos": 169725726, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022515.3", "url": "https://www.ensembl.org/id/ENSSSCT00000022515.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024321.1", "url": "https://www.ensembl.org/id/ENSSSCP00000024321.1" } ] } }, { "isoform_ac": "A0A4X1SUV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4/entry#A0A4X1SUV4-1", "sequence": { "sequence": "MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKRPALQSSVVATSKERTRRDLIQDQNMDEKGKQRKFKELNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKSEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIGIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVESVKNVIAEQEVMETNQVESIEPSENETSKELEPEMEFEVEPDKECKSLSPAKENSSALEMENEPEEKEEKESEPQPEPMSQPQPLPQPQPQSQPQPQPQAQTQAQCQSQSQPALQPQPLSQPETMPLAVLQPPPQAIQEQGHLPPERKEFPVESAKLTEVTVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTTSSSESRSRSRGRGHNRDRKHRRSVDRKRRDASGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR", "length": 736, "header": "tr|A0A4X1SUV4-1|A0A4X1SUV4_PIG Isoform 1 of Pinin OS=Sus scrofa OX=9823 GN=PNN PE=1 SV=1 CANONICAL=A0A4X1SUV4-1" }, "locus": { "chromosome": "1", "start_pos": 169732907, "end_pos": 169725726, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055104.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055104.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035570.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035570.2" } ] } }, { "isoform_ac": "A0A4X1SUY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4/entry#A0A4X1SUY2-1", "sequence": { "sequence": "MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKREPTNIWLVDGHASEI", "length": 124, "header": "tr|A0A4X1SUY2-1|A0A4X1SUY2_PIG Computationally mapped isoform of Pinin, desmosome associated protein OS=Sus scrofa OX=9823 GN=PNN PE=4 SV=1 CANONICAL=A0A4X1SUV4-1" }, "locus": { "chromosome": "1", "start_pos": 169728808, "end_pos": 169725726, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069032.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069032.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060361.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060361.1" } ] } }, { "isoform_ac": "A0A4X1SV98-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4/entry#A0A4X1SV98-1", "sequence": { "sequence": "MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKRPALQSSVVATSKERTRRDLIQDQNMDEKGKQRKFKELNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKSEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIGIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEEVMETNQVESIEPSENETSKELEPEMEFEVEPDKECKSLSPAKENSSALEMENEPEEKEEKESEPQPEPMSQPQPLPQPQPQSQPQPQPQAQTQAQCQSQSQPALQPQPLSQPETMPLAVLQPPPQAIQEQGHLPPERKEFPVESAKLTEVTVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTTSSSESRSRSRGRGHNRDRKHRRSVDRKRRDASGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR", "length": 718, "header": "tr|A0A4X1SV98-1|A0A4X1SV98_PIG Computationally mapped isoform of Pinin OS=Sus scrofa OX=9823 GN=PNN PE=1 SV=1 CANONICAL=A0A4X1SUV4-1" }, "locus": { "chromosome": "1", "start_pos": 169732907, "end_pos": 169725726, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087936.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087936.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070988.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070988.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUU5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUU5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100526149", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100526149", "resource": "KEGG Pathway" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUV4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUV4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUV4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUV4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUV4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUV4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUV4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUV4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" } ], "pmid": "" }, { "name": "exon-exon junction complex", "id": "GO:0035145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035145", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUV4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" }, { "id": "PF04697", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04697" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pinin/SDK", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 132, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUV4" }, { "id": "PF04696", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04696" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pinin/SDK/MemA protein", "eco_id": "ECO_0000259", "start_pos": 145, "end_pos": 265, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 424, "end_pos": 426 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 587, "end_pos": 589 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1STN7-1", "uniprot_ac": "A0A4X1STN7", "uniprot_id": "A0A4X1STN7_PIG", "mass": { "chemical_mass": 18237.0, "monoisotopic_mass": 18237.0 }, "refseq": { "ac": "XP_003128416", "name": "peptidyl-prolyl cis-trans isomerase-like 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128416" }, "gene_names": [ { "name": "PPIL1", "type": "recommended", "evidence": [ { "id": "A0A4X1STN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7" } ] }, { "name": "PPIL1", "type": "synonym", "evidence": [ { "id": "XP_003128416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128416" } ] } ], "protein_names": [ { "name": "Peptidyl-prolyl cis-trans isomerase", "type": "recommended", "evidence": [ { "id": "A0A4X1STN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7/entry#names_and_taxonomy" } ] }, { "name": "5.2.1.8", "type": "synonym", "evidence": [ { "id": "A0A4X1STN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7/entry#names_and_taxonomy" } ] }, { "name": "PPIase", "type": "synonym", "evidence": [ { "id": "A0A4X1STN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7/entry#names_and_taxonomy" } ] }, { "name": "peptidyl-prolyl cis-trans isomerase-like 1", "type": "synonym", "evidence": [ { "id": "XP_003128416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128416" } ] } ], "function": [ { "annotation": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STN7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7#function" }, { "database": "UniProtKB", "id": "RU363019", "url": "https://www.uniprot.org/uniprotkb/RU363019#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STN7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PPIL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7", "locus": { "chromosome": "7", "start_pos": 32522733, "end_pos": 32547839, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040984", "url": "https://www.ensembl.org/id/ENSSSCG00000040984" } ] } } ], "crossref": [ { "id": "A0A4X1STN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1STN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01922", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01922", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524445", "url": "https://www.ncbi.nlm.nih.gov/gene/100524445", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524445", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524445", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ELYNDHA", "url": "https://omabrowser.org/oma/group/ELYNDHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1STN7", "url": "https://www.orthodb.org/?gene=A0A4X1STN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45625", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45625", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45625:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45625:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003128416", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128416", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1STN7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1STN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAIPPDSWQPPNVYLETSMGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTGRGGASIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNSQDRPVDDVKIIKAYPSG", "length": 166, "header": "tr|A0A4X1STN7-1|A0A4X1STN7_PIG Isoform 1 of Peptidyl-prolyl cis-trans isomerase OS=Sus scrofa OX=9823 GN=PPIL1 PE=1 SV=1 CANONICAL=A0A4X1STN7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1STN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7/entry#A0A4X1STN7-1", "sequence": { "sequence": "MAAIPPDSWQPPNVYLETSMGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTGRGGASIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNSQDRPVDDVKIIKAYPSG", "length": 166, "header": "tr|A0A4X1STN7-1|A0A4X1STN7_PIG Isoform 1 of Peptidyl-prolyl cis-trans isomerase OS=Sus scrofa OX=9823 GN=PPIL1 PE=1 SV=1 CANONICAL=A0A4X1STN7-1" }, "locus": { "chromosome": "7", "start_pos": 32544243, "end_pos": 32523716, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061082.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061082.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042623.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042623.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STN7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524445", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524445", "resource": "KEGG Pathway" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PW44-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase", "gene_name": "PPIL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAVPPDSWQPPTVSMETTMGTLVLELYWRHAPRTCKNFAELCRRGYYNGTRFHRVIRDFMVQGGDPTGTGRGGASIYGKHFEDELHSELKFTGAGILAMANAGPDTNGSQFFITLAPAQWLDGKHTIFGRVCQGIGVLGRVGMVETNAQDRPLDDVKVLKAVPAG", "length": 166 }, "evidence": [ { "id": "A0A4X1STN7", "url": "https://omabrowser.org/oma/group/A0A4X1STN7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HKD0-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase", "gene_name": "Ppil1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAIPPDTWQPPNVYLETSMGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTGRGGASIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNSQDRPVDDVKILKAYPSG", "length": 166 }, "evidence": [ { "id": "A0A4X1STN7", "url": "https://omabrowser.org/oma/group/A0A4X1STN7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5E992-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase-like 1", "gene_name": "PPIL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAIPPDSWQPPNVYLETSMGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTGRGGASIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNSQDRPVDDVKIIKAYPSG", "length": 166 }, "evidence": [ { "id": "A0A4X1STN7", "url": "https://omabrowser.org/oma/group/A0A4X1STN7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D0W5-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase-like 1", "gene_name": "Ppil1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAIPPDTWQPPNVYLETSMGVIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTGRGGASIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNSQDRPVDDVKILKAYPSG", "length": 166 }, "evidence": [ { "id": "A0A4X1STN7", "url": "https://omabrowser.org/oma/group/A0A4X1STN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NI62-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase cypE", "gene_name": "cypE", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEQTVTLQTTVGDITLELYYNHAPKACKNFYELSKRGYYDNTIFHRLIKDFMIQGGDPLGNGRGGESIYGKKFEDEITKELKHTGAGILSMANSGVNSNGSQFFITFGPTPWLDGKHTIFGRVKSGMKVVQKMNAMQTNNDKPIDEIRIIKATAN", "length": 156 }, "evidence": [ { "id": "A0A4X1STN7", "url": "https://omabrowser.org/oma/group/A0A4X1STN7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9SIH1-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase CYP18-2", "gene_name": "CYP18-2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSARPEGSPPEVTLETSMGPFTVEMYYKHSPRTCRNFLELSRRGYYDNVLFHRIVKDFIVQGGDPTGTGRGGESIYGSKFEDEINKELKHTGAGILSMANAGPNTNGSQFFITLAPQPSLDGKHTIFGRVCRGMEVIKRLGSVQTDNTDRPIHEVKILRTKVID", "length": 164 }, "evidence": [ { "id": "A0A4X1STN7", "url": "https://omabrowser.org/oma/group/A0A4X1STN7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W0Q2-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase", "gene_name": "Cypl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLSLSDPNNAGGIPDKAWQPHFVTLETSMGEITVELYWKHAPNTCRNFAELSRRGYYNNVVFHRIIRDFMIQGGDPTGTGRGGASIYGSEFADELHGDLRHTGAGILSMANSGPDTNGSQFFITLAPTQWLDGKHTIFGRVYTGMEVVKRIGMVETDKNDRPVDPLRIIKAKVEKL", "length": 176 }, "evidence": [ { "id": "A0A4X1STN7", "url": "https://omabrowser.org/oma/group/A0A4X1STN7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y3C6-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase-like 1", "gene_name": "PPIL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAIPPDSWQPPNVYLETSMGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTGRGGASIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNSQDRPVDDVKIIKAYPSG", "length": 166 }, "evidence": [ { "id": "A0A4X1STN7", "url": "https://omabrowser.org/oma/group/A0A4X1STN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STN7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STN7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STN7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STN7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STN7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7" } ], "pmid": "" }, { "name": "embryonic brain development", "id": "GO:1990403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990403", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STN7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "disordered domain specific binding", "id": "GO:0097718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097718", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STN7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1STN7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] }, { "id": "R-SSC-9770141", "name": "Formation of the Spliceosomal C* complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-5688092", "R-SSC-5688093", "R-SSC-72073", "R-SSC-9769591", "R-SSC-9769593", "R-SSC-9769594", "R-SSC-9769596", "R-SSC-9769598", "R-SSC-9769599", "R-SSC-9769601" ], "output_participant_list": [ "R-SSC-72060", "R-SSC-8867898", "R-SSC-9770419", "R-SSC-9770425", "R-SSC-9770427", "R-SSC-9770428", "R-SSC-9770430" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9770141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770141" } ] }, { "id": "R-SSC-9770236", "name": "Formation of the Spliceosomal P complex and exon ligation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-9769588", "R-SSC-9769590", "R-SSC-9769602" ], "output_participant_list": [ "R-SSC-6791189", "R-SSC-8849139", "R-SSC-8952113", "R-SSC-9769562" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9770236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770236" } ] }, { "id": "R-SSC-9770847", "name": "Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-5688097", "R-SSC-8869310", "R-SSC-8869311", "R-SSC-9770846" ], "output_participant_list": [ "R-SSC-3900136", "R-SSC-6814858", "R-SSC-8865888", "R-SSC-8865956", "R-SSC-8952110", "R-SSC-9769561", "R-SSC-8867893", "R-SSC-9769592" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9770847", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770847" } ] }, { "id": "R-SSC-9794542", "name": "Formation of the Spliceosomal C complex containing intron lariat", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9794542", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9794542" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-3900136", "participant_name": "DDX5 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000043632", "database": "ENSEMBL", "url": "" }, { "id": "87226", "database": "VGNC", "url": "" }, { "id": "A0A287AHW6", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000032092", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000038465", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-5688092", "participant_name": "DHX8 [nucleoplasm]", "crossref": [ { "id": "F1S1H3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000017378", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000018412", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000018917", "database": "ENSEMBL", "url": "" }, { "id": "87298", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-5688093", "participant_name": "PRPF18 [nucleoplasm]", "crossref": [ { "id": "A0A4X1VY37", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000026354", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000027625", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000024330", "database": "ENSEMBL", "url": "" }, { "id": "NP_001231788.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-5688097", "participant_name": "DHX15 [nucleoplasm]", "crossref": [ { "id": "F1S5A8", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000008756", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000009333", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000009580", "database": "ENSEMBL", "url": "" }, { "id": "87286", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-6791189", "participant_name": "MTREX [nucleoplasm]", "crossref": [ { "id": "F1SLL6", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000017920", "database": "ENSEMBL", "url": "" }, { "id": "90470", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000018417", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000016911", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-6814858", "participant_name": "SRRT [nucleoplasm]", "crossref": [ { "id": "I3LI05", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000023704", "database": "ENSEMBL", "url": "" }, { "id": "93471", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000024767", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000024789", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-72060", "participant_name": "DHX38 [nucleoplasm]", "crossref": [ { "id": "F1S3A8", "database": "UniProt", "url": "" }, { "id": "XP_020949516.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000002966", "database": "ENSEMBL", "url": "" }, { "id": "87294", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000003045", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000002748", "database": "ENSEMBL", "url": "" }, { "id": "XP_020949515.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-72073", "participant_name": "SLU7 [nucleoplasm]", "crossref": [ { "id": "F1RR54", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000017033", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000018045", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000018545", "database": "ENSEMBL", "url": "" }, { "id": "XP_003134141.1", "database": "RefSeq", "url": "" }, { "id": "93214", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-8849139", "participant_name": "DDX39B [nucleoplasm]", "crossref": [ { "id": "XP_005665850.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000001487", "database": "ENSEMBL", "url": "" }, { "id": "NP_001005157.1", "database": "RefSeq", "url": "" }, { "id": "Q29024", "database": "UniProt", "url": "" }, { "id": "ENSSSCT00000001529", "database": "ENSEMBL", "url": "" }, { "id": "XP_005665851.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCG00000001400", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-8865888", "participant_name": "SRRM2 [nucleoplasm]", "crossref": [ { "id": "ENSSSCG00000023304", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000051053", "database": "ENSEMBL", "url": "" }, { "id": "93468", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000041895", "database": "ENSEMBL", "url": "" }, { "id": "A0A287ADD0", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-8865956", "participant_name": "CWC22 [nucleoplasm]", "crossref": [ { "id": "XP_003133562.2", "database": "RefSeq", "url": "" }, { "id": "XP_013839769.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000016961", "database": "ENSEMBL", "url": "" }, { "id": "A0A4X1TWU8", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000016008", "database": "ENSEMBL", "url": "" }, { "id": "XP_005672046.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCT00000017430", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-8867893", "participant_name": "PPWD1 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000017953", "database": "ENSEMBL", "url": "" }, { "id": "NP_001231350.1", "database": "RefSeq", "url": "" }, { "id": "F1SKT8", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000016945", "database": "ENSEMBL", "url": "" }, { "id": "91766", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000018453", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-8867898", "participant_name": "CWC25 [nucleoplasm]", "crossref": [ { "id": "ENSSSCT00000053706", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000021478", "database": "ENSEMBL", "url": "" }, { "id": "87096", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000032040", "database": "ENSEMBL", "url": "" }, { "id": "A0A286ZKR9", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-8869310", "participant_name": "TFIP11 [nucleoplasm]", "crossref": [ { "id": "Q06AK6", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000009962", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000010632", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000010917", "database": "ENSEMBL", "url": "" }, { "id": "XP_020927865.1", "database": "RefSeq", "url": "" }, { "id": "XP_020927864.1", "database": "RefSeq", "url": "" }, { "id": "NP_001070682.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-8869311", "participant_name": "GCFC2 [nucleoplasm]", "crossref": [ { "id": "I3LDF5", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000021287", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000022086", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000031635", "database": "ENSEMBL", "url": "" }, { "id": "XP_020942970.1", "database": "RefSeq", "url": "" }, { "id": "88382", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-8952110", "participant_name": "PPIL3 [nucleoplasm]", "crossref": [ { "id": "XP_013839835.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCT00000017525", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000016096", "database": "ENSEMBL", "url": "" }, { "id": "XP_001926016.1", "database": "RefSeq", "url": "" }, { "id": "XP_005672124.1", "database": "RefSeq", "url": "" }, { "id": "103073", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000017053", "database": "ENSEMBL", "url": "" }, { "id": "XP_001925960.1", "database": "RefSeq", "url": "" }, { "id": "F2Z5T7", "database": "UniProt", "url": "" }, { "id": "XP_005672126.1", "database": "RefSeq", "url": "" }, { "id": "XP_005672125.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-8952113", "participant_name": "PPIL4 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000023314", "database": "ENSEMBL", "url": "" }, { "id": "91699", "database": "VGNC", "url": "" }, { "id": "I3LGX0", "database": "UniProt", "url": "" }, { "id": "ENSSSCT00000024741", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000028867", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769561", "participant_name": "CCDC12 [nucleoplasm]", "crossref": [ { "id": "A0A8W4FDT6", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000077421", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000093297", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000011329", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769562", "participant_name": "PPIL2 [nucleoplasm]", "crossref": [ { "id": "ENSSSCG00000010083", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000056926", "database": "ENSEMBL", "url": "" }, { "id": "91698", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000040807", "database": "ENSEMBL", "url": "" }, { "id": "A0A287AAH2", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-9769588", "participant_name": "C1H9orf78 [nucleoplasm]", "crossref": [ { "id": "F1RQE0", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000030426", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000022510", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000024953", "database": "ENSEMBL", "url": "" }, { "id": "85975", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769590", "participant_name": "LENG1 [nucleoplasm]", "crossref": [ { "id": "F1RNH2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000003265", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000003541", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000003626", "database": "ENSEMBL", "url": "" }, { "id": "XP_003127463.2", "database": "RefSeq", "url": "" }, { "id": "89680", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769591", "participant_name": "CACTIN [nucleoplasm]", "crossref": [ { "id": "A0A287BJU2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000032085", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000056347", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000037250", "database": "ENSEMBL", "url": "" }, { "id": "86131", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769592", "participant_name": "PPIG [nucleoplasm]", "crossref": [ { "id": "XP_005671972.1", "database": "RefSeq", "url": "" }, { "id": "XP_020931930.1", "database": "RefSeq", "url": "" }, { "id": "XP_005671971.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000047092", "database": "ENSEMBL", "url": "" }, { "id": "XP_020931929.1", "database": "RefSeq", "url": "" }, { "id": "A0A4X1VJX6", "database": "UniProt", "url": "" }, { "id": "XP_020931927.1", "database": "RefSeq", "url": "" }, { "id": "XP_005671973.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCG00000031123", "database": "ENSEMBL", "url": "" }, { "id": "XP_001926896.1", "database": "RefSeq", "url": "" }, { "id": "XP_020931928.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCT00000066047", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769593", "participant_name": "SDE2 [nucleoplasm]", "crossref": [ { "id": "A0A8W4FFC9", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000010858", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000078134", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000092221", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769594", "participant_name": "PRKRIP1 [nucleoplasm]", "crossref": [ { "id": "A0A5G2QNT3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000042324", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000065720", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000069793", "database": "ENSEMBL", "url": "" }, { "id": "XP_005661993.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9769596", "participant_name": "STEEP1 [nucleoplasm]", "crossref": [ { "id": "F2Z566", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000012622", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000013420", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000013801", "database": "ENSEMBL", "url": "" }, { "id": "87113", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769598", "participant_name": "FAM32A [nucleoplasm]", "crossref": [ { "id": "A0A4X1UYF2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000013855", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000014729", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000015134", "database": "ENSEMBL", "url": "" }, { "id": "NP_001230816.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9769599", "participant_name": "FAM50A [nucleoplasm]", "crossref": [ { "id": "A0A5G2QKU3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000025303", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000064609", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000089389", "database": "ENSEMBL", "url": "" }, { "id": "87972", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769601", "participant_name": "DDX41 [nucleoplasm]", "crossref": [ { "id": "A0A287AWY6", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000032642", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000048662", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000059325", "database": "ENSEMBL", "url": "" }, { "id": "87221", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769602", "participant_name": "NKAP [nucleoplasm]", "crossref": [ { "id": "A0A5G2RJX5", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000012613", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000072270", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000085170", "database": "ENSEMBL", "url": "" }, { "id": "90756", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9770419", "participant_name": "GPATCH1 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000003085", "database": "ENSEMBL", "url": "" }, { "id": "XP_020949947.1", "database": "RefSeq", "url": "" }, { "id": "F1RNW7", "database": "UniProt", "url": "" }, { "id": "88573", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000003166", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000002865", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9770425", "participant_name": "WDR70 [nucleoplasm]", "crossref": [ { "id": "ENSSSCT00000018344", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000016846", "database": "ENSEMBL", "url": "" }, { "id": "94937", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000017848", "database": "ENSEMBL", "url": "" }, { "id": "F1SN94", "database": "UniProt", "url": "" }, { "id": "XP_020932620.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9770427", "participant_name": "DHX35 [nucleoplasm]", "crossref": [ { "id": "95678", "database": "VGNC", "url": "" }, { "id": "ENSSSCG00000007352", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000063112", "database": "ENSEMBL", "url": "" }, { "id": "A0A287B5Q0", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000051779", "database": "ENSEMBL", "url": "" }, { "id": "XP_001929057.3", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9770428", "participant_name": "NSRP1 [nucleoplasm]", "crossref": [ { "id": "A0A8D1TUT0", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000018853", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000019367", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000017795", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9770430", "participant_name": "YJU2 [nucleoplasm]", "crossref": [ { "id": "ENSSSCG00000013499", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000072636", "database": "ENSEMBL", "url": "" }, { "id": "95033", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000068755", "database": "ENSEMBL", "url": "" }, { "id": "A0A5G2QX80", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-9770846", "participant_name": "CWF19L2 [nucleoplasm]", "crossref": [ { "id": "A0A5K1V0N0", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000028201", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000028057", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000026318", "database": "ENSEMBL", "url": "" }, { "id": "96726", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1STN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1STN7" }, { "id": "PS50072", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50072" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPIase cyclophilin-type", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 164, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SU02-1", "uniprot_ac": "A0A4X1SU02", "uniprot_id": "A0A4X1SU02_PIG", "mass": { "chemical_mass": 34904.0, "monoisotopic_mass": 34904.0 }, "refseq": {}, "gene_names": [ { "name": "ATG3", "type": "recommended", "evidence": [ { "id": "A0A4X1SU02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ] } ], "protein_names": [ { "name": "Ubiquitin-like-conjugating enzyme ATG3", "type": "recommended", "evidence": [ { "id": "A0A4X1SU02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02/entry#names_and_taxonomy" } ] }, { "name": "Autophagy-related protein 3", "type": "synonym", "evidence": [ { "id": "A0A4X1SU02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ATG3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02", "locus": { "chromosome": "13", "start_pos": 147309590, "end_pos": 147279437, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011930", "url": "https://www.ensembl.org/id/ENSSSCG00000011930" } ] } } ], "crossref": [ { "id": "A0A4X1SU02", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SU02", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011930", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011930", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12866", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12866", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12866:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12866:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03987", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03987", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SU02-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0S2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6H1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6H1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FN04", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FN04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FN04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FN04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SLS7", "url": "https://www.uniprot.org/uniprotkb/F1SLS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SLS7-1", "url": "https://www.uniprot.org/uniprotkb/F1SLS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHNTGIAGITEAVKEITLESKDGIKLQDCSALCEEEEEEDEGEAADMEEYEESGLLETDEATLDTRKIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYPYLCMVANWLLTPPLLGNLV", "length": 309, "header": "tr|A0A4X1SU02-1|A0A4X1SU02_PIG Isoform 1 of Ubiquitin-like-conjugating enzyme ATG3 OS=Sus scrofa OX=9823 GN=ATG3 PE=3 SV=1 CANONICAL=A0A4X1SU02-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SU02-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02/entry#A0A4X1SU02-1", "sequence": { "sequence": "MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHNTGIAGITEAVKEITLESKDGIKLQDCSALCEEEEEEDEGEAADMEEYEESGLLETDEATLDTRKIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYPYLCMVANWLLTPPLLGNLV", "length": 309, "header": "tr|A0A4X1SU02-1|A0A4X1SU02_PIG Isoform 1 of Ubiquitin-like-conjugating enzyme ATG3 OS=Sus scrofa OX=9823 GN=ATG3 PE=3 SV=1 CANONICAL=A0A4X1SU02-1" }, "locus": { "chromosome": "13", "start_pos": 147307293, "end_pos": 147279828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082594.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082594.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064404.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064404.2" } ] } }, { "isoform_ac": "A0A5G2R0S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02/entry#A0A5G2R0S2-1", "sequence": { "sequence": "MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHNTGKRRTEWHMFKLFKLFYCSALCEEEEEEDEGEAADMEGIYATLDTRKIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEHVLWFQQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM", "length": 304, "header": "tr|A0A5G2R0S2-1|A0A4X1SU02_PIG Computationally mapped isoform of Ubiquitin-like-conjugating enzyme ATG3 OS=Sus scrofa OX=9823 GN=ATG3 PE=3 SV=2 CANONICAL=A0A4X1SU02-1" }, "locus": { "chromosome": "13", "start_pos": 147309409, "end_pos": 147279828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074195.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074195.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069975.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069975.2" } ] } }, { "isoform_ac": "A0A5G2R6H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02/entry#A0A5G2R6H1-1", "sequence": { "sequence": "MAMGNRGRIEKSGLLETDEATLDTRKIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM", "length": 163, "header": "tr|A0A5G2R6H1-1|A0A4X1SU02_PIG Computationally mapped isoform of Ubiquitin-like-conjugating enzyme ATG3 OS=Sus scrofa OX=9823 GN=ATG3 PE=3 SV=1 CANONICAL=A0A4X1SU02-1" }, "locus": { "chromosome": "13", "start_pos": 147309409, "end_pos": 147287222, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091171.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091171.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066195.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066195.1" } ] } }, { "isoform_ac": "A0A8W4FN04-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02/entry#A0A8W4FN04-1", "sequence": { "sequence": "MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHNTGKRRTEWHMFKLFKLFYCSALCEEEEEEDEGEAADMEGIYATLDTRKIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHISSQS", "length": 276, "header": "tr|A0A8W4FN04-1|A0A4X1SU02_PIG Computationally mapped isoform of Ubiquitin-like-conjugating enzyme ATG3 OS=Sus scrofa OX=9823 GN=ATG3 PE=3 SV=1 CANONICAL=A0A4X1SU02-1" }, "locus": { "chromosome": "13", "start_pos": 147307920, "end_pos": 147279828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096956.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096956.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080278.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080278.1" } ] } }, { "isoform_ac": "F1SLS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02/entry#F1SLS7-1", "sequence": { "sequence": "MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHNTGIAGITEAVKEITLESKDGIKLQDCSALCEEEEEEDEGEAADMEEYEESGLLETDEATLDTRKIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM", "length": 305, "header": "tr|F1SLS7-1|F1SLS7_PIG Computationally mapped isoform of Ubiquitin-like-conjugating enzyme ATG3 OS=Sus scrofa OX=9823 GN=ATG3 PE=1 SV=3 CANONICAL=A0A4X1SU02-1" }, "locus": { "chromosome": "13", "start_pos": 147309409, "end_pos": 147279828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013054.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013054.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012711.4", "url": "https://www.ensembl.org/id/ENSSSCP00000012711.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FN04", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FN04" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1632852", "resource": "Reactome", "description": "Macroautophagy" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "mitochondrial fragmentation involved in apoptotic process", "id": "GO:0043653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043653", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "regulation of cilium assembly", "id": "GO:1902017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902017", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "glycophagy", "id": "GO:0061723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "Atg12-Atg5-Atg16 complex", "id": "GO:0034274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034274", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "Atg8-family ligase activity", "id": "GO:0019776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019776", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "Atg12 transferase activity", "id": "GO:0019777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019777", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "Atg8-family conjugating enzyme activity", "id": "GO:0141046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141046", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" }, { "name": "ubiquitin-like protein transferase activity", "id": "GO:0019787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019787", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU02", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SU15-1", "uniprot_ac": "A0A4X1SU15", "uniprot_id": "A0A4X1SU15_PIG", "mass": { "chemical_mass": 55613.0, "monoisotopic_mass": 55613.0 }, "refseq": { "ac": "XP_013852210", "name": "zinc finger protein PLAG1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013852210" }, "gene_names": [ { "name": "PLAG1", "type": "recommended", "evidence": [ { "id": "A0A4X1SU15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ] }, { "name": "PLAG1", "type": "synonym", "evidence": [ { "id": "XP_013852210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013852210" } ] } ], "protein_names": [ { "name": "PLAG1 zinc finger", "type": "synonym", "evidence": [ { "id": "A0A4X1SU15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein PLAG1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013852210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013852210" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PLAG1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15", "locus": { "chromosome": "4", "start_pos": 75694117, "end_pos": 75646584, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006247", "url": "https://www.ensembl.org/id/ENSSSCG00000006247" } ] } } ], "crossref": [ { "id": "A0A4X1SU15", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SU15", "database": "AlphaFoldDB", "categories": [] }, { "id": "100154905", "url": "https://www.ncbi.nlm.nih.gov/gene/100154905", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154905", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154905", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SU15", "url": "https://www.orthodb.org/?gene=A0A4X1SU15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013852210", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013852210", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SU15-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSSGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFPNTLQLNLYNTPFQPMQSSGSAHQMITTLPLGMTCPLDMDAVHPSHHLSFKYPFGSTSYAISIPEKEQPLKGEIESYLMELQGGAPSSSQDSPASSSKLGLEPPLGALDDGAGDLALSKSSISISDPLNTPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYAQEEAHSSVSQLPAPAQDLQDPANPIGLSSLHSLSAAFTSSLSTSTTLPRFHQAFQ", "length": 499, "header": "tr|A0A4X1SU15-1|A0A4X1SU15_PIG Isoform 1 of PLAG1 zinc finger OS=Sus scrofa OX=9823 GN=PLAG1 PE=4 SV=1 CANONICAL=A0A4X1SU15-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SU15-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15/entry#A0A4X1SU15-1", "sequence": { "sequence": "MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSSGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFPNTLQLNLYNTPFQPMQSSGSAHQMITTLPLGMTCPLDMDAVHPSHHLSFKYPFGSTSYAISIPEKEQPLKGEIESYLMELQGGAPSSSQDSPASSSKLGLEPPLGALDDGAGDLALSKSSISISDPLNTPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYAQEEAHSSVSQLPAPAQDLQDPANPIGLSSLHSLSAAFTSSLSTSTTLPRFHQAFQ", "length": 499, "header": "tr|A0A4X1SU15-1|A0A4X1SU15_PIG Isoform 1 of PLAG1 zinc finger OS=Sus scrofa OX=9823 GN=PLAG1 PE=4 SV=1 CANONICAL=A0A4X1SU15-1" }, "locus": { "chromosome": "4", "start_pos": 75691130, "end_pos": 75689145, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006846.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006846.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006660.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006660.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154905", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154905", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of glial cell proliferation", "id": "GO:0060252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060252", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SU15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SU15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SU15" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 61, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SUA0-1", "uniprot_ac": "A0A4X1SUA0", "uniprot_id": "A0A4X1SUA0_PIG", "mass": { "chemical_mass": 19330.0, "monoisotopic_mass": 19330.0 }, "refseq": { "ac": "XP_020954304", "name": "serine/arginine-rich splicing factor 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954304" }, "gene_names": [ { "name": "SRSF3", "type": "recommended", "evidence": [ { "id": "A0A4X1SUA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ] }, { "name": "SRSF3", "type": "synonym", "evidence": [ { "id": "XP_020954304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954304" } ] } ], "protein_names": [ { "name": "Serine/arginine-rich splicing factor 3", "type": "recommended", "evidence": [ { "id": "A0A4X1SUA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0/entry#names_and_taxonomy" } ] }, { "name": "Splicing factor, arginine/serine-rich 3", "type": "synonym", "evidence": [ { "id": "A0A4X1SUA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0/entry#names_and_taxonomy" } ] }, { "name": "serine/arginine-rich splicing factor 3", "type": "synonym", "evidence": [ { "id": "XP_020954304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954304" } ] } ], "function": [ { "annotation": "Splicing factor, which binds the consensus motif 5'-C[ACU][AU]C[ACU][AC]C-3' within pre-mRNA and promotes specific exons inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites within exons. Also functions as an adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0#function" }, { "database": "UniProtKB", "id": "ARBA00056175", "url": "https://www.uniprot.org/uniprotkb/ARBA00056175#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SRSF3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0", "locus": { "chromosome": "7", "start_pos": 32298580, "end_pos": 32289480, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001564", "url": "https://www.ensembl.org/id/ENSSSCG00000001564" } ] } } ], "crossref": [ { "id": "A0A4X1SUA0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SUA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12645", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12645", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100739153", "url": "https://www.ncbi.nlm.nih.gov/gene/100739153", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100739153", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739153", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EMHRDSC", "url": "https://omabrowser.org/oma/group/EMHRDSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SUA0", "url": "https://www.orthodb.org/?gene=A0A4X1SUA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72187", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72187", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72203", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72203", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020954304", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954304", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SUA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK", "length": 164, "header": "tr|A0A4X1SUA0-1|A0A4X1SUA0_PIG Isoform 1 of Serine/arginine-rich splicing factor 3 OS=Sus scrofa OX=9823 GN=SRSF3 PE=1 SV=1 CANONICAL=A0A4X1SUA0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SUA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0/entry#A0A4X1SUA0-1", "sequence": { "sequence": "MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK", "length": 164, "header": "tr|A0A4X1SUA0-1|A0A4X1SUA0_PIG Isoform 1 of Serine/arginine-rich splicing factor 3 OS=Sus scrofa OX=9823 GN=SRSF3 PE=1 SV=1 CANONICAL=A0A4X1SUA0-1" }, "locus": { "chromosome": "7", "start_pos": 32295799, "end_pos": 32291306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001743.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001743.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001699.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001699.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100739153", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739153", "resource": "KEGG Pathway" }, { "id": "R-SSC-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-SSC-72187", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72187", "resource": "Reactome", "description": "mRNA 3'-end processing" }, { "id": "R-SSC-72203", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72203", "resource": "Reactome", "description": "Processing of Capped Intron-Containing Pre-mRNA" }, { "id": "R-SSC-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "E1C8Y9-1", "protein_name": "Serine/arginine-rich splicing factor 3", "gene_name": "SRSF3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK", "length": 164 }, "evidence": [ { "id": "A0A4X1SUA0", "url": "https://omabrowser.org/oma/group/A0A4X1SUA0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "M9MS48-1", "protein_name": "Rbp1-like, isoform B", "gene_name": "Rbp1-like", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPRYREWDLACKVYVGNLGSSASKYEIENAFSKYGPLRNVWVARNPPGFAFVEFEDRRDAEDATRGLDGTRCCGTRIRVEMSSGRSREGRGGGGGGGGGGGGSGGGGRGGGSGARAGGGGRAGDGGGRYRIKSSSSTTTSTTRTTTTTTSIIIIIMIIKRTTKKKEKTTTATTTRTSTTPLPSTTTTKRTTTTATTRTTSTTADPAPPITHISPTTTTTTATTTPPPCNNNLLCGPNQKFNKFDIFR", "length": 247 }, "evidence": [ { "id": "A0A4X1SUA0", "url": "https://omabrowser.org/oma/group/A0A4X1SUA0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P84103-1", "protein_name": "Serine/arginine-rich splicing factor 3", "gene_name": "SRSF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK", "length": 164 }, "evidence": [ { "id": "A0A4X1SUA0", "url": "https://omabrowser.org/oma/group/A0A4X1SUA0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P84104-1", "protein_name": "Serine/arginine-rich splicing factor 3", "gene_name": "Srsf3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK", "length": 164 }, "evidence": [ { "id": "A0A4X1SUA0", "url": "https://omabrowser.org/oma/group/A0A4X1SUA0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3SZR8-1", "protein_name": "Serine/arginine-rich splicing factor 3", "gene_name": "SRSF3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK", "length": 164 }, "evidence": [ { "id": "A0A4X1SUA0", "url": "https://omabrowser.org/oma/group/A0A4X1SUA0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "pmid": "" }, { "name": "phospholipase binding", "id": "GO:0043274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043274", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "pmid": "" }, { "name": "primary miRNA binding", "id": "GO:0070878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070878", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "pmid": "" }, { "name": "protein-RNA sequence-specific adaptor activity", "id": "GO:0160134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160134", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "pmid": "" }, { "name": "primary miRNA processing", "id": "GO:0031053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031053", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUA0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SUA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUA0" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 83, "start_aa": "Cys", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SUG4-1", "uniprot_ac": "A0A4X1SUG4", "uniprot_id": "A0A4X1SUG4_PIG", "mass": { "chemical_mass": 21166.0, "monoisotopic_mass": 21166.0 }, "refseq": { "ac": "XP_001927451", "name": "regulator of G-protein signaling 10 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927451" }, "gene_names": [ { "name": "RGS10", "type": "recommended", "evidence": [ { "id": "A0A4X1SUG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4" } ] }, { "name": "RGS10", "type": "synonym", "evidence": [ { "id": "XP_001927451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927451" } ] } ], "protein_names": [ { "name": "Regulator of G protein signaling 10", "type": "synonym", "evidence": [ { "id": "A0A4X1SUG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4/entry#names_and_taxonomy" } ] }, { "name": "regulator of G-protein signaling 10 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_001927451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927451" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RGS10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4", "locus": { "chromosome": "14", "start_pos": 129381208, "end_pos": 129423702, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000039838", "url": "https://www.ensembl.org/id/ENSSSCG00000039838" } ] } } ], "crossref": [ { "id": "A0A4X1SUG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SUG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08741", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08741", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152559", "url": "https://www.ncbi.nlm.nih.gov/gene/100152559", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152559", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152559", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SNKASYQ", "url": "https://omabrowser.org/oma/group/SNKASYQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SUG4", "url": "https://www.orthodb.org/?gene=A0A4X1SUG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SW67", "url": "https://www.orthodb.org/?gene=A0A4X1SW67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45945", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45945", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45945:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45945:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001927451", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927451", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SUG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SUG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SW67", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SW67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SW67-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SW67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFNRAVSRLSRKRPPSDIHDSDGSASSSHQNPKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKTQDKKQMQEKAKEIYMTFLSSKASSQVNVEGQSRLNEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEDEDSTDAQTAAKRASRIYNT", "length": 181, "header": "tr|A0A4X1SUG4-1|A0A4X1SUG4_PIG Isoform 1 of Regulator of G protein signaling 10 OS=Sus scrofa OX=9823 GN=RGS10 PE=4 SV=1 CANONICAL=A0A4X1SUG4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SUG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4/entry#A0A4X1SUG4-1", "sequence": { "sequence": "MFNRAVSRLSRKRPPSDIHDSDGSASSSHQNPKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKTQDKKQMQEKAKEIYMTFLSSKASSQVNVEGQSRLNEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEDEDSTDAQTAAKRASRIYNT", "length": 181, "header": "tr|A0A4X1SUG4-1|A0A4X1SUG4_PIG Isoform 1 of Regulator of G protein signaling 10 OS=Sus scrofa OX=9823 GN=RGS10 PE=4 SV=1 CANONICAL=A0A4X1SUG4-1" }, "locus": { "chromosome": "14", "start_pos": 129423639, "end_pos": 129387053, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041381.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041381.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048629.3", "url": "https://www.ensembl.org/id/ENSSSCP00000048629.3" } ] } }, { "isoform_ac": "A0A4X1SW67-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4/entry#A0A4X1SW67-1", "sequence": { "sequence": "MAHIHDSDGSASSSHQNPKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKTQDKKQMQEKAKEIYMTFLSSKASSQVNVEGQSRLNEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEDEDSTDAQTAAKRASRIYNT", "length": 167, "header": "tr|A0A4X1SW67-1|A0A4X1SW67_PIG Computationally mapped isoform of Regulator of G protein signaling 10 OS=Sus scrofa OX=9823 GN=RGS10 PE=4 SV=1 CANONICAL=A0A4X1SUG4-1" }, "locus": { "chromosome": "14", "start_pos": 129417299, "end_pos": 129387053, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047393.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047393.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037430.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037430.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152559", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152559", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1RQE4-1", "protein_name": "Regulator of G protein signaling 10", "gene_name": "RGS10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFNRAVSRLSRKRPPSEINDSEGHPSSSRQSLKGTSEWATSLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEEFKKTQGKKQMREKAKEIYMTFLSNKASSQVNVEGQSRLNETILETPHPLMFQKLQDQIFNLMKYDSYSRFLKSDIFLNHKKSEEQEENSSEAQTAAKRASRIYNT", "length": 181 }, "evidence": [ { "id": "A0A4X1SUG4", "url": "https://omabrowser.org/oma/group/A0A4X1SUG4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O43665-3", "protein_name": "Regulator of G protein signaling 10", "gene_name": "RGS10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFNRAVSRLSRKRPPSDIHDSDGSSSSSHQSLKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKMQDKTQMQEKAKEIYMTFLSSKASSQVNVEGQSRLNEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEEEDLPDAQTAAKRASRIYNT", "length": 181 }, "evidence": [ { "id": "A0A4X1SUG4", "url": "https://omabrowser.org/oma/group/A0A4X1SUG4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49806-1", "protein_name": "Regulator of G protein signaling 10", "gene_name": "Rgs10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTRAVSRLSRKRPPSDIHDGDGSSSSGHQSLKSTAKWASSLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKTEDKKQMQEKAKKIYMTFLSNKASSQVNVEGQSRLTEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKHRRTEEEEEDPPDAQTAAKRASRIYNT", "length": 181 }, "evidence": [ { "id": "A0A4X1SUG4", "url": "https://omabrowser.org/oma/group/A0A4X1SUG4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KHW7-1", "protein_name": "Regulator of G protein signaling 10", "gene_name": "RGS10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFNRAVSRLSRKRPPSDIHDSDGSSSSSHQTPKSTAKWASSLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKTQDKKQMQEKAKEIYMTFLSSKASSQVNVEGQSRLNEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEDEESPDAQTAAKRASRIYNT", "length": 181 }, "evidence": [ { "id": "A0A4X1SUG4", "url": "https://omabrowser.org/oma/group/A0A4X1SUG4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CQE5-1", "protein_name": "Regulator of G protein signaling 10", "gene_name": "Rgs10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTRAVSRLSRKRPPSDIHDGDGSSSSGHQSLKSTAKWASSLENLLEDPEGVQRFREFLKKEFSEENVLFWLACEDFKKTEDRKQMQEKAKEIYMTFLSNKASSQVNVEGQSRLTEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKPKRTEEEEEEPPDAQTAAKRASRIYNT", "length": 181 }, "evidence": [ { "id": "A0A4X1SUG4", "url": "https://omabrowser.org/oma/group/A0A4X1SUG4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4" } ], "pmid": "" }, { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "G protein-coupled acetylcholine receptor signaling pathway", "id": "GO:0007213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007213", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SUG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUG4" }, { "id": "PS50132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RGS", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 154, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SUK0-1", "uniprot_ac": "A0A4X1SUK0", "uniprot_id": "A0A4X1SUK0_PIG", "mass": { "chemical_mass": 36901.0, "monoisotopic_mass": 36901.0 }, "refseq": { "ac": "XP_005664966", "name": "olfactory receptor 10C1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664966" }, "gene_names": [ { "name": "LOC100624276", "type": "recommended", "evidence": [ { "id": "A0A4X1SUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0" } ] }, { "name": "LOC100624276", "type": "synonym", "evidence": [ { "id": "XP_005664966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664966" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1SUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 10C1-like", "type": "synonym", "evidence": [ { "id": "XP_005664966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664966" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUK0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUK0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100624276", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0", "locus": {} } ], "crossref": [ { "id": "A0A4X1SUK0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SUK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15227", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15227", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100624276", "url": "https://www.ncbi.nlm.nih.gov/gene/100624276", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624276", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624276", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SUK0", "url": "https://www.orthodb.org/?gene=A0A4X1SUK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005664966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664966", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SUK0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SUK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNLTAVPVFVLRGFAEIPEIQLLSTAAFLLVYLAAILGNISIVAAVSLDARLHTPMYFFLKHLSLVDICSVSTTLPRALVATLLGSGQISLPACASQLFAFICLGSTECFLITCMAYDRCLAIYRPLVYRAAMSPRTCVSLVVVAWGSGLLYSAFHTANTFSLPFCGPNVIDHFFCDILPLMRLACAGARAHAAAGLAASGCVIISCFGLTVLSYVRILATVIQIRSVAGRWKAFSTCSSHLATVLLFYGTGSSAYMQTPARYSPRQGRLAAIFYSILTPTLNPLIYSLRNKDMKGSLRKLCLQGHLRVWKGPRNPASQGFPCGPGRSVPISRHHEDHTQ", "length": 341, "header": "tr|A0A4X1SUK0-1|A0A4X1SUK0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100624276 PE=3 SV=1 CANONICAL=A0A4X1SUK0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SUK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0/entry#A0A4X1SUK0-1", "sequence": { "sequence": "MTNLTAVPVFVLRGFAEIPEIQLLSTAAFLLVYLAAILGNISIVAAVSLDARLHTPMYFFLKHLSLVDICSVSTTLPRALVATLLGSGQISLPACASQLFAFICLGSTECFLITCMAYDRCLAIYRPLVYRAAMSPRTCVSLVVVAWGSGLLYSAFHTANTFSLPFCGPNVIDHFFCDILPLMRLACAGARAHAAAGLAASGCVIISCFGLTVLSYVRILATVIQIRSVAGRWKAFSTCSSHLATVLLFYGTGSSAYMQTPARYSPRQGRLAAIFYSILTPTLNPLIYSLRNKDMKGSLRKLCLQGHLRVWKGPRNPASQGFPCGPGRSVPISRHHEDHTQ", "length": 341, "header": "tr|A0A4X1SUK0-1|A0A4X1SUK0_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100624276 PE=3 SV=1 CANONICAL=A0A4X1SUK0-1" }, "locus": { "chromosome": "6", "start_pos": 61046963, "end_pos": 61045941, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101566.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101566.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078392.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078392.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUK0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624276", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624276", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUK0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUK0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUK0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SUK0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUK0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SVE5-1", "uniprot_ac": "A0A4X1SVE5", "uniprot_id": "A0A4X1SVE5_PIG", "mass": { "chemical_mass": 64882.0, "monoisotopic_mass": 64882.0 }, "refseq": {}, "gene_names": [ { "name": "IHO1", "type": "recommended", "evidence": [ { "id": "A0A4X1SVE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5" } ] } ], "protein_names": [ { "name": "Interactor of HORMAD1 1", "type": "synonym", "evidence": [ { "id": "A0A4X1SVE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IHO1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5", "locus": { "chromosome": "13", "start_pos": 31837912, "end_pos": 31802948, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011376", "url": "https://www.ensembl.org/id/ENSSSCG00000011376" } ] } } ], "crossref": [ { "id": "A0A4X1SVE5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SVE5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011376", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011376", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR031529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SVE5", "url": "https://www.orthodb.org/?gene=A0A4X1SVE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35662", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35662", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35662:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35662:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1SVE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SVE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SPT3", "url": "https://www.uniprot.org/uniprotkb/F1SPT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SPT3-1", "url": "https://www.uniprot.org/uniprotkb/F1SPT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNFNVWNIKEMLSIPSGSGTTRSSNWNNNQTDYSSLSDSQFLFGSQFCPESSETLSTPLDFGVHLRHPKQSQQNSLDSEPSIFTKYQTKPQLFGGDTKDGGLFPLPLSVGKSKGLLEQFEEKKKSAKDKCDSETLYNLISHIRESIHRLQTSVENSEEHLSSRSQTILDSLETVAKTLQETAQAQSDLVLETMQDKGNMKQAILELQKRFEARQAEFIEMKSNLKQLEVLVAQQSKDLQQLSEQLGQLNMPSVLAELKQLISVPQIPRHLKESTSQTSPPLAQSINFTRQGKNAFKEPVMWQTQALPTARNLSVGSLRPGEFDVWGVGAKSDALQEEATRVAVGTGKRNKQIKDKAVQTNCQNRAITKTASGILGHNVPSERDLVFQGASQLISLDLNNFAASIKNTCQKCQAKGMFLCDSCEQRLVNGQKGRTVERGRKGKKQQRKAPRGRLLARKQEQTTSKTCVSHSKYPQPPVSGPQRPPQGQQEALAQSLHLQGPRSPTKPVCSALGGTVMATKTVKSMQGNFLQLSGHASQDNSLLSCSSQGDHQMSWFSDLNLGREPPLCKELGKNTLYDLGFDSSDDGF", "length": 587, "header": "tr|A0A4X1SVE5-1|A0A4X1SVE5_PIG Isoform 1 of Interactor of HORMAD1 1 OS=Sus scrofa OX=9823 GN=IHO1 PE=4 SV=1 CANONICAL=A0A4X1SVE5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SVE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5/entry#A0A4X1SVE5-1", "sequence": { "sequence": "MNFNVWNIKEMLSIPSGSGTTRSSNWNNNQTDYSSLSDSQFLFGSQFCPESSETLSTPLDFGVHLRHPKQSQQNSLDSEPSIFTKYQTKPQLFGGDTKDGGLFPLPLSVGKSKGLLEQFEEKKKSAKDKCDSETLYNLISHIRESIHRLQTSVENSEEHLSSRSQTILDSLETVAKTLQETAQAQSDLVLETMQDKGNMKQAILELQKRFEARQAEFIEMKSNLKQLEVLVAQQSKDLQQLSEQLGQLNMPSVLAELKQLISVPQIPRHLKESTSQTSPPLAQSINFTRQGKNAFKEPVMWQTQALPTARNLSVGSLRPGEFDVWGVGAKSDALQEEATRVAVGTGKRNKQIKDKAVQTNCQNRAITKTASGILGHNVPSERDLVFQGASQLISLDLNNFAASIKNTCQKCQAKGMFLCDSCEQRLVNGQKGRTVERGRKGKKQQRKAPRGRLLARKQEQTTSKTCVSHSKYPQPPVSGPQRPPQGQQEALAQSLHLQGPRSPTKPVCSALGGTVMATKTVKSMQGNFLQLSGHASQDNSLLSCSSQGDHQMSWFSDLNLGREPPLCKELGKNTLYDLGFDSSDDGF", "length": 587, "header": "tr|A0A4X1SVE5-1|A0A4X1SVE5_PIG Isoform 1 of Interactor of HORMAD1 1 OS=Sus scrofa OX=9823 GN=IHO1 PE=4 SV=1 CANONICAL=A0A4X1SVE5-1" }, "locus": { "chromosome": "13", "start_pos": 31836908, "end_pos": 31802963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012454.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012454.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012129.4", "url": "https://www.ensembl.org/id/ENSSSCP00000012129.4" } ] } }, { "isoform_ac": "F1SPT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5/entry#F1SPT3-1", "sequence": { "sequence": "MNFNVWNIKEMLSIPSGSGTTRSSNWNNNQTDYSSLSDSQFLFGSQFCPESSETLSTPLDFGVHLRHPKQSQQNSLDSEPSIFTKYQTKPQLFGGDTKDGGLFPLPLSVGKSKGLLEQFEEKKKSAKDKCDSYRHLWKTLRNISVQEAKLFWILWRLWPRHVSVSCLRYQQGAMASSECELSDPSWVSASMGT", "length": 193, "header": "tr|F1SPT3-1|A0A4X1SVE5_PIG Computationally mapped isoform of Interactor of HORMAD1 1 OS=Sus scrofa OX=9823 GN=IHO1 PE=4 SV=2 CANONICAL=A0A4X1SVE5-1" }, "locus": { "chromosome": "13", "start_pos": 31830909, "end_pos": 31802963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012457.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012457.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012132.3", "url": "https://www.ensembl.org/id/ENSSSCP00000012132.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SPT3", "url": "https://www.uniprot.org/uniprotkb/F1SPT3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of homologous chromosome segregation", "id": "GO:0060629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060629", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5" } ], "pmid": "" }, { "name": "meiotic DNA double-strand break formation", "id": "GO:0042138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042138", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SVE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SVE5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 286, "end_pos": 288 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 311, "end_pos": 313 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SWA8-1", "uniprot_ac": "A0A4X1SWA8", "uniprot_id": "A0A4X1SWA8_PIG", "mass": { "chemical_mass": 13373.0, "monoisotopic_mass": 13373.0 }, "refseq": {}, "gene_names": [ { "name": "RPS20", "type": "recommended", "evidence": [ { "id": "A0A4X1SWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein uS10", "type": "recommended", "evidence": [ { "id": "A0A4X1SWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S20", "type": "synonym", "evidence": [ { "id": "A0A4X1SWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWA8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8#function" }, { "database": "UniProtKB", "id": "ARBA00045746", "url": "https://www.uniprot.org/uniprotkb/ARBA00045746#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWA8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPS20", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8", "locus": { "chromosome": "4", "start_pos": 75769955, "end_pos": 75762209, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040470", "url": "https://www.ensembl.org/id/ENSSSCG00000040470" } ] } } ], "crossref": [ { "id": "A0A4X1SWA8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SWA8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000040470", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000040470", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027486", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027486", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WCEYRRR", "url": "https://omabrowser.org/oma/group/WCEYRRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11700", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11700", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00338", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00338", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SWA8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SWA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q7Q1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q7Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q7Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q7Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119, "header": "tr|A0A4X1SWA8-1|A0A4X1SWA8_PIG Isoform 1 of Small ribosomal subunit protein uS10 OS=Sus scrofa OX=9823 GN=RPS20 PE=3 SV=1 CANONICAL=A0A4X1SWA8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SWA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8/entry#A0A4X1SWA8-1", "sequence": { "sequence": "MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119, "header": "tr|A0A4X1SWA8-1|A0A4X1SWA8_PIG Isoform 1 of Small ribosomal subunit protein uS10 OS=Sus scrofa OX=9823 GN=RPS20 PE=3 SV=1 CANONICAL=A0A4X1SWA8-1" }, "locus": { "chromosome": "4", "start_pos": 75763414, "end_pos": 75762329, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043834.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043834.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058493.1", "url": "https://www.ensembl.org/id/ENSSSCP00000058493.1" } ] } }, { "isoform_ac": "A0A5G2Q7Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8/entry#A0A5G2Q7Q1-1", "sequence": { "sequence": "MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKDSENNYEKNSLW", "length": 46, "header": "tr|A0A5G2Q7Q1-1|A0A4X1SWA8_PIG Computationally mapped isoform of Small ribosomal subunit protein uS10 OS=Sus scrofa OX=9823 GN=RPS20 PE=3 SV=1 CANONICAL=A0A4X1SWA8-1" }, "locus": { "chromosome": "4", "start_pos": 75763269, "end_pos": 75762329, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074749.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074749.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060134.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060134.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2Q7Q1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q7Q1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-SSC-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NH93-1", "protein_name": "Small ribosomal subunit protein uS10", "gene_name": "RPS20", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAFKDTGKAPVEQEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119 }, "evidence": [ { "id": "A0A4X1SWA8", "url": "https://omabrowser.org/oma/group/A0A4X1SWA8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P60866-1", "protein_name": "Small ribosomal subunit protein uS10", "gene_name": "RPS20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119 }, "evidence": [ { "id": "A0A4X1SWA8", "url": "https://omabrowser.org/oma/group/A0A4X1SWA8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P60867-1", "protein_name": "Small ribosomal subunit protein uS10", "gene_name": "Rps20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119 }, "evidence": [ { "id": "A0A4X1SWA8", "url": "https://omabrowser.org/oma/group/A0A4X1SWA8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P60868-1", "protein_name": "Small ribosomal subunit protein uS10", "gene_name": "Rps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119 }, "evidence": [ { "id": "A0A4X1SWA8", "url": "https://omabrowser.org/oma/group/A0A4X1SWA8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3ZBH8-1", "protein_name": "Small ribosomal subunit protein uS10", "gene_name": "RPS20", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119 }, "evidence": [ { "id": "A0A4X1SWA8", "url": "https://omabrowser.org/oma/group/A0A4X1SWA8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWA8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8" } ], "pmid": "" }, { "name": "MDM2/MDM4 family protein binding", "id": "GO:0097371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097371", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWA8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8" } ], "pmid": "" }, { "name": "ubiquitin ligase inhibitor activity", "id": "GO:1990948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990948", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWA8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWA8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWA8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWA8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWA8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8" } ], "pmid": "" }, { "name": "positive regulation of signal transduction by p53 class mediator", "id": "GO:1901798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901798", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWA8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWA8" }, { "id": "SM01403", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01403" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small ribosomal subunit protein uS10", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 115, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SWN4-1", "uniprot_ac": "A0A4X1SWN4", "uniprot_id": "A0A4X1SWN4_PIG", "mass": { "chemical_mass": 25569.0, "monoisotopic_mass": 25569.0 }, "refseq": { "ac": "XP_020918538", "name": "platelet-activating factor acetylhydrolase IB subunit beta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918538" }, "gene_names": [ { "name": "PAFAH1B2", "type": "recommended", "evidence": [ { "id": "A0A4X1SWN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4" } ] }, { "name": "PAFAH1B2", "type": "synonym", "evidence": [ { "id": "XP_020918538", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918538" } ] } ], "protein_names": [ { "name": "Platelet-activating factor acetylhydrolase IB subunit alpha2", "type": "recommended", "evidence": [ { "id": "A0A4X1SWN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.47", "type": "synonym", "evidence": [ { "id": "A0A4X1SWN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4/entry#names_and_taxonomy" } ] }, { "name": "PAF acetylhydrolase 30 kDa subunit", "type": "synonym", "evidence": [ { "id": "A0A4X1SWN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4/entry#names_and_taxonomy" } ] }, { "name": "PAF-AH subunit beta", "type": "synonym", "evidence": [ { "id": "A0A4X1SWN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4/entry#names_and_taxonomy" } ] }, { "name": "platelet-activating factor acetylhydrolase IB subunit beta", "type": "synonym", "evidence": [ { "id": "XP_020918538", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918538" } ] } ], "function": [ { "annotation": "Alpha2 catalytic subunit of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)) heterotetrameric enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and modulates the action of PAF. The activity and substrate specificity of PAF-AH (I) are affected by its subunit composition. The alpha2/alpha2 homodimer (PAFAH1B2/PAFAH1B2 homodimer) hydrolyzes PAF and 1-O-alkyl-2-acetyl-sn-glycero-3-phosphorylethanolamine (AAGPE) more efficiently than 1-O-alkyl-2-acetyl-sn-glycero-3-phosphoric acid (AAGPA). In contrast, the alpha1/alpha2 heterodimer(PAFAH1B3/PAFAH1B3 heterodimer) hydrolyzes AAGPA more efficiently than PAF, but has little hydrolytic activity towards AAGPE. May play a role in male germ cell meiosis during the late pachytenestage and meiotic divisions as well as early spermiogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYQ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYQ6#function" }, { "database": "UniProtKB", "id": "ARBA00045566", "url": "https://www.uniprot.org/uniprotkb/ARBA00045566#function" }, { "database": "UniProtKB", "id": "A0A4X1SWN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PAFAH1B2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4", "locus": { "chromosome": "9", "start_pos": 44536432, "end_pos": 44513461, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000024027", "url": "https://www.ensembl.org/id/ENSSSCG00000024027" } ] } } ], "crossref": [ { "id": "A0A4X1SWN4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SWN4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01820", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01820", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523683", "url": "https://www.ncbi.nlm.nih.gov/gene/100523683", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013830", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013830", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036514", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036514", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523683", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523683", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AWNQYFA", "url": "https://omabrowser.org/oma/group/AWNQYFA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SWN4", "url": "https://www.orthodb.org/?gene=A0A4X1SWN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11852", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11852", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11852:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11852:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13472", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13472", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6811436", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020918538", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918538", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17777", "url": "https://www.rhea-db.org/rhea/17777", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40479", "url": "https://www.rhea-db.org/rhea/40479", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41704", "url": "https://www.rhea-db.org/rhea/41704", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41708", "url": "https://www.rhea-db.org/rhea/41708", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SWN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SWN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SYQ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SYQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA", "length": 229, "header": "tr|A0A4X1SWN4-1|A0A4X1SWN4_PIG Isoform 1 of Platelet-activating factor acetylhydrolase IB subunit alpha2 OS=Sus scrofa OX=9823 GN=PAFAH1B2 PE=1 SV=1 CANONICAL=A0A4X1SWN4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SWN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4/entry#A0A4X1SWN4-1", "sequence": { "sequence": "MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA", "length": 229, "header": "tr|A0A4X1SWN4-1|A0A4X1SWN4_PIG Isoform 1 of Platelet-activating factor acetylhydrolase IB subunit alpha2 OS=Sus scrofa OX=9823 GN=PAFAH1B2 PE=1 SV=1 CANONICAL=A0A4X1SWN4-1" }, "locus": { "chromosome": "9", "start_pos": 44531277, "end_pos": 44521103, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064464.2", "url": "https://www.ensembl.org/id/ENSSSCT00000064464.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044888.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044888.1" } ] } }, { "isoform_ac": "A0A4X1SYQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4/entry#A0A4X1SYQ6-1", "sequence": { "sequence": "MSQGDSNPAAIPHAAEDIQGDDRWMSQIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA", "length": 199, "header": "tr|A0A4X1SYQ6-1|A0A4X1SYQ6_PIG Computationally mapped isoform of Platelet-activating factor acetylhydrolase IB subunit alpha2 OS=Sus scrofa OX=9823 GN=PAFAH1B2 PE=1 SV=1 CANONICAL=A0A4X1SWN4-1" }, "locus": { "chromosome": "9", "start_pos": 44531277, "end_pos": 44521103, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027329.4", "url": "https://www.ensembl.org/id/ENSSSCT00000027329.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022294.2", "url": "https://www.ensembl.org/id/ENSSSCP00000022294.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523683", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523683", "resource": "KEGG Pathway" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-6811436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811436", "resource": "Reactome", "description": "COPI-independent Golgi-to-ER retrograde traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZR27-1", "protein_name": "Platelet-activating factor acetylhydrolase IB subunit alpha2", "gene_name": "PAFAH1B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALGMPCCAAPSSFCSSLWNKMSHGDSNPAAVPHAADDIQGDDRWMSQHNRFVSDCKDKEPDVLFVGDSMVQLLQQYEIWRELFSPLHALNFGIGGDTTGHVLWRLKNGELENIKPKVIVVWVGTNNYGNTAEEVAGGIEAIVRLINTQQPQAKVIVLGLLPRGEKPNPLRQKNAKVNHLLKASLPKLPNVQLLDVDAGFVHSDGTISYHDMFDFLHLTGGAYAKICKPLHELIMQLLEETPEEKRAALA", "length": 250 }, "evidence": [ { "id": "A0A4X1SWN4", "url": "https://omabrowser.org/oma/group/A0A4X1SWN4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O35264-1", "protein_name": "Platelet-activating factor acetylhydrolase IB subunit alpha2", "gene_name": "Pafah1b2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDIDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA", "length": 229 }, "evidence": [ { "id": "A0A4X1SWN4", "url": "https://omabrowser.org/oma/group/A0A4X1SWN4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P68401-1", "protein_name": "Platelet-activating factor acetylhydrolase IB subunit alpha2", "gene_name": "PAFAH1B2P68402", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA", "length": 229 }, "evidence": [ { "id": "A0A4X1SWN4", "url": "https://omabrowser.org/oma/group/A0A4X1SWN4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P68402-1", "protein_name": "Platelet-activating factor acetylhydrolase IB subunit alpha2", "gene_name": "PAFAH1B2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA", "length": 229 }, "evidence": [ { "id": "A0A4X1SWN4", "url": "https://omabrowser.org/oma/group/A0A4X1SWN4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61206-1", "protein_name": "Platelet-activating factor acetylhydrolase IB subunit alpha2", "gene_name": "Pafah1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDIDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA", "length": 229 }, "evidence": [ { "id": "A0A4X1SWN4", "url": "https://omabrowser.org/oma/group/A0A4X1SWN4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VXP4-1", "protein_name": "Platelet-activating factor acetylhydrolase IB subunit beta homolog", "gene_name": "Paf-AHalpha", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNPCVLPTPLPDLDGDKRWHSIHRRFISDCREKDPDVIFLGDCIFETVQDTEAWNKYFAPLHCLNFSIRDDCTEHVLWRIENGALDNVNPKIVVLHVGTNNVRNSAEEVAEGVLANVTKIRQKLPNAYIVLPSLLPRGQQPNKLREKNAKINEVVNGLTKGLYRVQTVAIDKGLVQTDGSISHHDMFDYKNLTNAGAKKILEPLYDLLSQILNENEPENDLTPSE", "length": 225 }, "evidence": [ { "id": "A0A4X1SWN4", "url": "https://omabrowser.org/oma/group/A0A4X1SWN4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "platelet-activating factor acetyltransferase activity", "id": "GO:0047179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047179", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4" } ], "pmid": "" }, { "name": "1-alkyl-2-acetylglycerophosphocholine esterase activity", "id": "GO:0003847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003847", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4" } ], "pmid": "" }, { "name": "1-alkyl-2-acetylglycerophosphocholine esterase complex", "id": "GO:0008247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008247", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4" } ], "pmid": "" }, { "name": "positive regulation of macroautophagy", "id": "GO:0016239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016239", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SWN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17777", "name": "", "equation": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17777", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17777" } ] }, { "id": "40479", "name": "", "equation": "1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "40479", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40479" } ] }, { "id": "41704", "name": "", "equation": "1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + H2O = 1-O-hexadecyl-sn-glycero-3-phosphate + acetate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "41704", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41704" } ] }, { "id": "41708", "name": "", "equation": "1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphoethanolamine + acetate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "41708", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41708" } ] }, { "id": "R-SSC-6798748", "name": "Exocytosis of secretory granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, secretory granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6798748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798748" } ] }, { "id": "R-SSC-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6800434" } ] }, { "id": "R-SSC-8848484", "name": "PLA2s hydrolyze phospholipids at the Golgi membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-6814303", "R-ALL-8848483" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8848484", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8848484" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6814303", "participant_name": "fatty acid [cytosol]", "crossref": [ { "id": "35366", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-8848483", "participant_name": "2-lysophosphatidylcholine [Golgi membrane]", "crossref": [ { "id": "C04230", "database": "COMPOUND", "url": "" }, { "id": "17504", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SWN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SWN4" }, { "id": "PF13472", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13472" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SGNH hydrolase-type esterase", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 203, "start_aa": "Phe", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SX03-1", "uniprot_ac": "A0A4X1SX03", "uniprot_id": "A0A4X1SX03_PIG", "mass": { "chemical_mass": 10989.0, "monoisotopic_mass": 10989.0 }, "refseq": { "ac": "XP_005666831", "name": "C-X-C motif chemokine 11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666831" }, "gene_names": [ { "name": "CXCL11", "type": "recommended", "evidence": [ { "id": "A0A4X1SX03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ] }, { "name": "CXCL11", "type": "synonym", "evidence": [ { "id": "XP_005666831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666831" } ] } ], "protein_names": [ { "name": "C-X-C motif chemokine", "type": "recommended", "evidence": [ { "id": "A0A4X1SX03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03/entry#names_and_taxonomy" } ] }, { "name": "C-X-C motif chemokine 11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005666831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666831" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CXCL11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03", "locus": { "chromosome": "8", "start_pos": 71713803, "end_pos": 71725674, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008978", "url": "https://www.ensembl.org/id/ENSSSCG00000008978" } ] } } ], "crossref": [ { "id": "A0A4X1SX03", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SX03", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100169744", "url": "https://www.ncbi.nlm.nih.gov/gene/100169744", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ANKGQRC", "url": "https://omabrowser.org/oma/group/ANKGQRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SX03", "url": "https://www.orthodb.org/?gene=A0A4X1SX03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12015:SF191", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12015:SF191", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00048", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00048", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005666831", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666831", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SX03-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVKGMAIVLAVIFCATTIQGFPMFKAGRCLCIGPGVKAVKVADIEKVSIIHPSNNCDKTEVIVTLKAHKGRRCLNPKSKQANVIMKKVERMNFLKYQNV", "length": 100, "header": "tr|A0A4X1SX03-1|A0A4X1SX03_PIG Isoform 1 of C-X-C motif chemokine OS=Sus scrofa OX=9823 GN=CXCL11 PE=3 SV=1 CANONICAL=A0A4X1SX03-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SX03-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03/entry#A0A4X1SX03-1", "sequence": { "sequence": "MGVKGMAIVLAVIFCATTIQGFPMFKAGRCLCIGPGVKAVKVADIEKVSIIHPSNNCDKTEVIVTLKAHKGRRCLNPKSKQANVIMKKVERMNFLKYQNV", "length": 100, "header": "tr|A0A4X1SX03-1|A0A4X1SX03_PIG Isoform 1 of C-X-C motif chemokine OS=Sus scrofa OX=9823 GN=CXCL11 PE=3 SV=1 CANONICAL=A0A4X1SX03-1" }, "locus": { "chromosome": "8", "start_pos": 71715696, "end_pos": 71714478, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009833.6", "url": "https://www.ensembl.org/id/ENSSSCT00000009833.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009580.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009580.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QDM0-1", "protein_name": "C-X-C motif chemokine", "gene_name": "Cxcl11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNMKGMAIALAVIICATTIQGFSVFKRGRCLCIGPLAKAVKMADIETVSILHRSYSCDKVEVIVTLKAQKRQRCLDPNSKQGRLIQAIAEKKSLRQGNM", "length": 99 }, "evidence": [ { "id": "A0A4X1SX03", "url": "https://omabrowser.org/oma/group/A0A4X1SX03/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A9QWQ1-1", "protein_name": "C-X-C motif chemokine 11", "gene_name": "CXCL11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSVKGMAIVLTVILCAAIVQGFPMFKGGRCLCIGPGVKAVKVADIEKVSIIYPTNNCDKTEVIITLKTHKGQRCLNPKAKQAKAIIKKVQRKNSEKYKNI", "length": 100 }, "evidence": [ { "id": "A0A4X1SX03", "url": "https://omabrowser.org/oma/group/A0A4X1SX03/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O14625-1", "protein_name": "C-X-C motif chemokine 11", "gene_name": "CXCL11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVKGMAIALAVILCATVVQGFPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKGQRCLNPKSKQARLIIKKVERKNF", "length": 94 }, "evidence": [ { "id": "A0A4X1SX03", "url": "https://omabrowser.org/oma/group/A0A4X1SX03/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "defense response", "id": "GO:0006952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006952", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" }, { "name": "chemokine-mediated signaling pathway", "id": "GO:0070098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070098", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" }, { "name": "positive regulation of release of sequestered calcium ion into cytosol", "id": "GO:0051281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051281", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" }, { "name": "T cell chemotaxis", "id": "GO:0010818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010818", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" }, { "name": "neutrophil activation", "id": "GO:0042119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042119", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" }, { "name": "neutrophil chemotaxis", "id": "GO:0030593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030593", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" }, { "name": "chemokine activity", "id": "GO:0008009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008009", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" }, { "name": "CXCR3 chemokine receptor binding", "id": "GO:0048248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048248", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX03", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SX03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX03" }, { "id": "SM00199", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00199" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chemokine interleukin-8-like", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 89, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SX72-1", "uniprot_ac": "A0A4X1SX72", "uniprot_id": "A0A4X1SX72_PIG", "mass": { "chemical_mass": 48626.0, "monoisotopic_mass": 48626.0 }, "refseq": { "ac": "XP_003132721", "name": "palmitoyltransferase ZDHHC23 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132721" }, "gene_names": [ { "name": "ZDHHC23", "type": "recommended", "evidence": [ { "id": "A0A4X1SX72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72" } ] }, { "name": "ZDHHC23", "type": "synonym", "evidence": [ { "id": "XP_003132721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132721" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "A0A4X1SX72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "A0A4X1SX72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72/entry#names_and_taxonomy" } ] }, { "name": "palmitoyltransferase ZDHHC23 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003132721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132721" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZDHHC23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72", "locus": { "chromosome": "13", "start_pos": 145970851, "end_pos": 145997044, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011914", "url": "https://www.ensembl.org/id/ENSSSCG00000011914" } ] } } ], "crossref": [ { "id": "A0A4X1SX72", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SX72", "database": "AlphaFoldDB", "categories": [] }, { "id": "100515099", "url": "https://www.ncbi.nlm.nih.gov/gene/100515099", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515099", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515099", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GNWSEFM", "url": "https://omabrowser.org/oma/group/GNWSEFM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SX72", "url": "https://www.orthodb.org/?gene=A0A4X1SX72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22883", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22883", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22883:SF475", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22883:SF475", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003132721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132721", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SX72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SX72-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHKGTMKPVKKNKAEEPELEPLCCCEYIDRNGEKNHVAACLCDCQDLDEGCDRWITCKSVQPETCERIMDTISDRLRIPWLRGAKKVNISILPPLFLLPVFLRVASWHFLLGVVVLTSLPVLALWYYYLTHRRKEQTLFFLSLGLFSLGYMYYVFLQEVVPKGRVRPTQLALLTCGLFLILLALYRAKKNPGYLRKSVSNDRSLNGSQIESLNRKGFPGADPSGSLNNRTSKDEPKGSWAPSGSPAKAREDWCAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQAFILALSIFLLTSVYGITLTLDTICRDRSVFTALFYCPGVYADNSSALCFTCVWYSVIITAGLAYIFLIQLINISYNVTEREVQQALRQKTGRRLLCGLIVDTGQYNRGFLRNWHQFSTLGSHPFHHPAEDIV", "length": 428, "header": "tr|A0A4X1SX72-1|A0A4X1SX72_PIG Isoform 1 of Palmitoyltransferase OS=Sus scrofa OX=9823 GN=ZDHHC23 PE=3 SV=1 CANONICAL=A0A4X1SX72-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SX72-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72/entry#A0A4X1SX72-1", "sequence": { "sequence": "MTHKGTMKPVKKNKAEEPELEPLCCCEYIDRNGEKNHVAACLCDCQDLDEGCDRWITCKSVQPETCERIMDTISDRLRIPWLRGAKKVNISILPPLFLLPVFLRVASWHFLLGVVVLTSLPVLALWYYYLTHRRKEQTLFFLSLGLFSLGYMYYVFLQEVVPKGRVRPTQLALLTCGLFLILLALYRAKKNPGYLRKSVSNDRSLNGSQIESLNRKGFPGADPSGSLNNRTSKDEPKGSWAPSGSPAKAREDWCAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQAFILALSIFLLTSVYGITLTLDTICRDRSVFTALFYCPGVYADNSSALCFTCVWYSVIITAGLAYIFLIQLINISYNVTEREVQQALRQKTGRRLLCGLIVDTGQYNRGFLRNWHQFSTLGSHPFHHPAEDIV", "length": 428, "header": "tr|A0A4X1SX72-1|A0A4X1SX72_PIG Isoform 1 of Palmitoyltransferase OS=Sus scrofa OX=9823 GN=ZDHHC23 PE=3 SV=1 CANONICAL=A0A4X1SX72-1" }, "locus": { "chromosome": "13", "start_pos": 145996149, "end_pos": 145986719, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013037.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013037.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012694.3", "url": "https://www.ensembl.org/id/ENSSSCP00000012694.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515099", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515099", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HQY8-1", "protein_name": "Palmitoyltransferase", "gene_name": "Zdhhc23", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKPVKKKKTEEPELEPLCCCEYIDRNGEKNHVAACLCDCQDLDEGCDRWLSCKSVRPETCERITDTISDRLRIPWLRGAKKVNISIVPPLVLLPVFLHVASWHFLLGVVVLISLPMLALWYYYLTHRRKEQTLFFLSLGLFSLGYMYYVFLREVVPKGRVGPTQLALLTFGLFLILLALYRAKKDPGYLSNPACNDKAPSNSQIECPIKKGQEKTKGFPGTDTSGSLNNRTLKDDIKGSSRVGLDSPAKVKEDWCAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQAFILALLIFLLTSVYGISLTLNTICRDRSLFIALFYCPGVYENYSSALSFTCVWYSVIITAGMAYIFLIQLINISYNVTEREVQQALRQKTGRRLLCGLIVDTGQYNRGFLRNWYQFSTLGAHTAHIPAEDIV", "length": 429 }, "evidence": [ { "id": "A0A4X1SX72", "url": "https://omabrowser.org/oma/group/A0A4X1SX72/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9TVJ9-1", "protein_name": "Palmitoyltransferase", "gene_name": "ZDHHC23", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKPVKKTKAEEPELEPLCCCEYIDRNGEKNHVAACLCDCQDLDEGCDRWITCKSVQPETCEKIMDTISDRLRIPWLRGAKKVNISILPPLFLLPVFLRVASWHFLLGVVVLTSLPVLALWYYYLTHRRKEQTLFFLSLGLFSLGYMYYVFLQEVVPKGRVGPTRLALLTCGLLLILFALYRAKKNPGYLRNPAHNDRALSGSQVECLNRKGPEKPKGFPSADLSGGLNNRAPKDETKDSPRTSAGSPAKGKDDWCAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQAFILALLVFLLTSVYGITLTLDTICTDRSVFTALFYCPGVYANYSSALCFTCVWYSVIITGSMAYIFLIQLINISYNVTEREVQQALRQKTGRRLLCGLIVDTGQYNRGFLRNWHQFSTLGAHPFHHPAEDIV", "length": 429 }, "evidence": [ { "id": "A0A4X1SX72", "url": "https://omabrowser.org/oma/group/A0A4X1SX72/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QX91-1", "protein_name": "Palmitoyltransferase ZDHHC23-B", "gene_name": "zdhhc23b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSIMKKRSSRAADPDELLCCCEYIDRHGSRSHMVACCCDCEDLDEACDRWMNKEPQNPDSVSRALATINDRLRVPWISGARQIDVSLIPPLILLPVFLHIAALHYLLGIIMLTAMPITVLWYYFFTHRKKGRTLFFLGLALFSLFYMFYLFLTQVVPRGEVTELQLAVVTAGVALTVIFLMLTKRGPGLVRPRPSETHSTVTYHSTPPDVDGVYLNGARHQVVIGSRVASSEHTGEPGTEEEEEGVQKRNWCAVCKVVRPQRAGHCRICGVCVLRLDHHCVWINSCVGLANHRTFLLTLLFFLLTSIYGISLVLASVCPDQRVLTALFYCPDVYSQYSSALCFTCAWYSSIVTGGLLHLLLLQILNISLNVTEREARLALREKSAQRRLWGLIVHTGHYSRGFWSNWTEFLTMTEDTQPAGHKTEDLV", "length": 428 }, "evidence": [ { "id": "A0A4X1SX72", "url": "https://omabrowser.org/oma/group/A0A4X1SX72/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5Y5T3-1", "protein_name": "Palmitoyltransferase ZDHHC23", "gene_name": "Zdhhc23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPVKKKKTEEPELEPLCCCEYIDRNGEKNHVAACLCDCQDLDEGCDRWLTCQSLRPETCERITDTISDRLRIPWLRGAKKVNISIVPPLVLLPVFLHVASWHFLLGVVVLTSLPMLALWYYYLTHRRKEQTLFFLSLGLFSLGYMYYVFLREVVPQGRVGPTQLALLTCGLLLILLALYRAKKNPGYLSNDKSPSNSQIECPVKKGQEKTKGFPGTDASGSLNNRTLKDDVRGSSRVGLDSPAKVKEDWCAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQAFILALSIFLLTSVYGISLTLNTICRDRSLFTALFYCPGVYANYSSALSFTCVWYSVIITAGMAYIFLIQLINISYNVTEREVQQALRQKTGRRLLCGLIVDTGQYNRGFLRNWLQFSTLGTHTVHTPAEDIV", "length": 425 }, "evidence": [ { "id": "A0A4X1SX72", "url": "https://omabrowser.org/oma/group/A0A4X1SX72/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYP9-1", "protein_name": "Palmitoyltransferase ZDHHC23", "gene_name": "ZDHHC23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQKGSMKPVKKKKTEEPELEPLCCCEYIDRNGEKNHVATCLCDCQDLDEGCDRWITCKSLQPETCERIMDTISDRLRIPWLRGAKKVNISIIPPLVLLPVFLHVASWHFLLGVVVLTSLPVLALWYYYLTHRRKEQTLFFLSLGLFSLGYMYYVFLQEVVPKGRVGPVQLAVLTCGLFLILLALHRAKKNPGYLSNPASGDRSLSSSQLECLSRKGQEKTKGFPGADMSGSLNNRTTKDDPKGSSKMPAGSPTKAKEDWCAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQAFILALLIFLLTSVYGITLTLDTICRDRSVFTALFYCPGVYANYSSALSFTCVWYSVIITAGMAYIFLIQLINISYNVTEREVQQALRQKTGRRLLCGLIVDTGLLG", "length": 409 }, "evidence": [ { "id": "A0A4X1SX72", "url": "https://omabrowser.org/oma/group/A0A4X1SX72/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VQK9-1", "protein_name": "Protein beta4GalNAcTB pilot", "gene_name": "GABPI", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFLMTAGTSNFLSAAWRSEAEESKSKENGSLCCCEYVAEDSRERSHILGCCCNCVDFDLVCTRLVTCRAIDRRNIDGMLIAFQDRLRLPWRGGAKRISPAAVAPAFIVPLMLGLATLNSKTAIVLMLTLVGFTIWGMELAKRTATRTNFFLSWLVFSVFYMIIIFEFQVPLLELAPEENYALMFFSCAALYCLYSAKALSPLNLVSAQYGTTPKDELPGIAEASSGEEQAEAQTTLQMESVLSLDDDEVGDMDTAERSGLMHGQPNICEICRKVTPRRAYHCPVCGTCVKRRDHHSYWLNCCIGERNYVWYIVGLALSEIALLLGANLTLTSICHPFMVVRPLGYPVLLPDDCSEVFEGFDLGISFVVACYALLISSYIAFILARQAYLWWKGSTLHEYKRTSNAAGRNRIWSNWRAILK", "length": 420 }, "evidence": [ { "id": "A0A4X1SX72", "url": "https://omabrowser.org/oma/group/A0A4X1SX72/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72" } ], "pmid": "" }, { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SX72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX72" }, { "id": "PF01529", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Palmitoyltransferase DHHC", "eco_id": "ECO_0000259", "start_pos": 249, "end_pos": 379, "start_aa": "Ala", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SX84-1", "uniprot_ac": "A0A4X1SX84", "uniprot_id": "A0A4X1SX84_PIG", "mass": { "chemical_mass": 85836.0, "monoisotopic_mass": 85836.0 }, "refseq": { "ac": "XP_020918539", "name": "proprotein convertase subtilisin/kexin type 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918539" }, "gene_names": [ { "name": "PCSK7", "type": "recommended", "evidence": [ { "id": "A0A4X1SX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84" } ] }, { "name": "PCSK7", "type": "synonym", "evidence": [ { "id": "XP_020918539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918539" } ] } ], "protein_names": [ { "name": "Proprotein convertase subtilisin/kexin type 7", "type": "recommended", "evidence": [ { "id": "A0A4X1SX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84/entry#names_and_taxonomy" } ] }, { "name": "Prohormone convertase 7", "type": "synonym", "evidence": [ { "id": "A0A4X1SX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84/entry#names_and_taxonomy" } ] }, { "name": "Proprotein convertase 7", "type": "synonym", "evidence": [ { "id": "A0A4X1SX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84/entry#names_and_taxonomy" } ] }, { "name": "Subtilisin/kexin-like protease PC7", "type": "synonym", "evidence": [ { "id": "A0A4X1SX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84/entry#names_and_taxonomy" } ] }, { "name": "proprotein convertase subtilisin/kexin type 7", "type": "synonym", "evidence": [ { "id": "XP_020918539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918539" } ] } ], "function": [ { "annotation": "Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive secretory pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84#function" }, { "database": "UniProtKB", "id": "ARBA00054142", "url": "https://www.uniprot.org/uniprotkb/ARBA00054142#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PCSK7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84", "locus": { "chromosome": "9", "start_pos": 44567577, "end_pos": 44596484, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015072", "url": "https://www.ensembl.org/id/ENSSSCG00000015072" } ] } } ], "crossref": [ { "id": "A0A4X1SX84", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SX84", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523009", "url": "https://www.ncbi.nlm.nih.gov/gene/100523009", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523009", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523009", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGRMPFY", "url": "https://omabrowser.org/oma/group/NGRMPFY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SX84", "url": "https://www.orthodb.org/?gene=A0A4X1SX84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42884:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42884:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00082", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00082", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01483", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01483", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9768727", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9768727", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020918539", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918539", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SX84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SX84-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKGRQKVPHSDAPLGLPARLWLELAGLFLLLPWVMGLVGAGGPGAQGPGGLSWAVHLDHPEGEGEADLLEQQADALAQAAGLVNAGRIGELQGHYLLVQPAGHPQPQQAEAVRQQVEAVLARHEAVRWHSEQRLLKRAKRSIHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATQYEDRHADWITNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKEDKAIPLSARPLEVLWNVSRTDLEMSGLKTLEHVAVTVSITHPRRGSLEVKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDEKSQAGILRQWQLTLYGSVWSPVDIRDRQRLLESAMSGKYLHDGFTLPCPPGLKIPEEDGYTITPNTLKTLVLIGCFTVFWTIYYMLEVYLSQRNVASHPVCRSGPCHWPQQSRKAKEEGTELEAVPLCSSQDPGGVGTESEGPSAPSRLRAPDLLDQGDWSLSQNRGALDCPQRLPPDLLQGKGEQIC", "length": 786, "header": "tr|A0A4X1SX84-1|A0A4X1SX84_PIG Isoform 1 of Proprotein convertase subtilisin/kexin type 7 OS=Sus scrofa OX=9823 GN=PCSK7 PE=3 SV=1 CANONICAL=A0A4X1SX84-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SX84-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84/entry#A0A4X1SX84-1", "sequence": { "sequence": "MPKGRQKVPHSDAPLGLPARLWLELAGLFLLLPWVMGLVGAGGPGAQGPGGLSWAVHLDHPEGEGEADLLEQQADALAQAAGLVNAGRIGELQGHYLLVQPAGHPQPQQAEAVRQQVEAVLARHEAVRWHSEQRLLKRAKRSIHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATQYEDRHADWITNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKEDKAIPLSARPLEVLWNVSRTDLEMSGLKTLEHVAVTVSITHPRRGSLEVKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDEKSQAGILRQWQLTLYGSVWSPVDIRDRQRLLESAMSGKYLHDGFTLPCPPGLKIPEEDGYTITPNTLKTLVLIGCFTVFWTIYYMLEVYLSQRNVASHPVCRSGPCHWPQQSRKAKEEGTELEAVPLCSSQDPGGVGTESEGPSAPSRLRAPDLLDQGDWSLSQNRGALDCPQRLPPDLLQGKGEQIC", "length": 786, "header": "tr|A0A4X1SX84-1|A0A4X1SX84_PIG Isoform 1 of Proprotein convertase subtilisin/kexin type 7 OS=Sus scrofa OX=9823 GN=PCSK7 PE=3 SV=1 CANONICAL=A0A4X1SX84-1" }, "locus": { "chromosome": "9", "start_pos": 44594025, "end_pos": 44568611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016438.4", "url": "https://www.ensembl.org/id/ENSSSCT00000016438.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015996.4", "url": "https://www.ensembl.org/id/ENSSSCP00000015996.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 531, "start_aa": "Thr", "end_pos": 531, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr531", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523009", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523009", "resource": "KEGG Pathway" }, { "id": "R-SSC-9768727", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9768727", "resource": "Reactome", "description": "Regulation of CDH1 posttranslational processing and trafficking to plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1P8P5-1", "protein_name": "3.4.21.-", "gene_name": "pcsk7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASCSSRVCLGLYPLLLLFSSSSSSCAPGRSWAVQLQPDSLSSAGSPDLLAQAVAQDVGLRSHGQIGQLEGHYLLCQDPAQGEDWRWMEAALDRHPHVAWHSQENVLRRSKRSVHFNDPKFPSQWHLHNDMKRGMDINVTGVWERNITGAGVTVVVVDDGIQHNLADIQPNYSPEGSYDLNSNDPDPMPHPDGPSDNHHGTRCAGEIAAVSNNSFCAVGVAYGSRVAGIRVLDGPLTDSMEAIAFNKHYQVNDIYSCSWGPDDDGRTVDGPHPLGKAALQHGVIAGRKGFGSIFIVASGNGGQNQDNCNYDGYANSIYTVTIGAVDESGRKPTYAEECASMLAVTFSSGNTPLRSIVTSDWSLQSGTGCTSGHTGTSAAAPLAAGMVALMLQVRPCLSWRDVQHIITYTATQHDLQADWVTNGAGFHHSHKYGFGLLNAWRLVNAAKVWESVPFLVSYQSPVLRVNEVITTSTNLTQTWNVSESDLQRSGMQTLEHVSVTLSIQHPRRGNLQILLLCPSGISSLIGARRALDVDSAGLTDWTFSTVRCWGEQAEGQYSLLIMDDAPLSSGILKSWKLTLYGSSLSHQQVTDRQRVVEEAMSGHYLSSSFSLPCPPGIDVPAEIVNPFTSSSLKSLLLLGCFTLFWSLYYTLEVVLTHWDWRGGCVRGRDGDAGYSRLSRDEAQTDPQQVEVLLETHSQDKVLLIADTHT", "length": 709 }, "evidence": [ { "id": "A0A4X1SX84", "url": "https://omabrowser.org/oma/group/A0A4X1SX84/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0ZRB7-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "PCSK7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPHRERRLRRWSAGAQAVRCVHTCLWLGAAWIPSVLSHGLTRGTELDDGRAVAHGPGELAWAVSLDVPEEQVEQRAEQLARTAGLVNMGRIGELKGHYLFSYRPDSHAAPEPEAIRRSVDTLFAQHDSVRWHSEQKLLKRSKRSLHFNDPKYPQQWHLNNRKSPGKDINVTGVWERNVTGRGVTVVVVDDGVEHTIKDIQPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAAVPNNSFCTVGVAYGSRIAGIRVLDGPLTDSMEAIAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRRGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEMGSMPFYAEECASMLAVTFSGGDKMMRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATKYEDRHAKWDVNRAGFSHSHQHGFGLLNAWRLVNAAKIWESVPYLASYVSPVLKEGRSIPLLPQELEATWNVTTTDLQLSGMRTLEHVAVTVTITHPRRGNLEIRLFCPSGMMSLIGTTRSMDSDPNGFADWTFSTVRCWGEEAQGTYRLVIRDTGDQSLRPGTLKQWQLTLYGSSWSPAEMKERQRLLEEAMSGQYLNNDFSLPCPPGLEIPEQQHYTITANTLKTLLLLGCFAVFWTFYYMLEVCLSRNNVGLDLTCHGSTACRWYQQGGKHRALENGLEMESVPLYREKEVEDIEVECELLEPVQEDTGEEGSWTPTLPKLPASSRAAAPTTAGYLGREAAAELLADDRELQTC", "length": 799 }, "evidence": [ { "id": "A0A4X1SX84", "url": "https://omabrowser.org/oma/group/A0A4X1SX84/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BEJ2-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "PCSK7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKGRQKVPHSDAPLGLPTGLWLELAGLFLLLPWVMGLVGAGGPRAQGPRGLSWAVRLDGPEGEGAEESLERRADALAQATGLMNAGRIGELQGHYLLVQPAGHRQARQVKAIRQQVEAVLARHEAVRWHSEQRLLKRTKRGVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDLENGNHHGTRCAGEIAAVPNNSFCAVGVAFGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATRYEDRHADWITNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKENKAIPLSARPLEVLWNVSRMDLDMSGLKTLEHVAVTISITHPRRGSLEVKLFCPSGMMSLIGAPRSLDSDPNGFNDWTFSTVRCWGERAKGTYRLVIRDVGDETSQAGVLRQWQLTLYGSVWSPVDIRDRQRLLESAMSGKYLHDGFTLPCPPGLNIPEEDGYTITPNTLKTLVLIGCFTVFWTIYYTLEVYLSQRNVAFGPICRSGPCHWPQRSQKAKEEGTELESMPLCSSQDPGGVGLESEGSPTTSRLHAPDLLDQGDWSLSQSRGALDVPQLLPPDLLQGKEAQMC", "length": 786 }, "evidence": [ { "id": "A0A4X1SX84", "url": "https://omabrowser.org/oma/group/A0A4X1SX84/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3IAK2-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "Pcsk7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPKGRQKVPHLDAPLGLPICLWLELAGLLFMVPWVMGLSEASGLDSLGAGGLSWAVHLDSLEGERKEESLMQQADALAQAAGLVNAGRIGELQGHYLLVQPAGHKQAMEVEAMRQQAEAVLAQHEAVRWHSEQKLLKRAKRSIHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDAENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDIQHIIVFTATQYEDHHADWLTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKENKAVPRSPNSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLAIRDVGDEPLQVGILRQWQLTLYGSMWSPVDIKDRQSLLESAMSGKYLHDGFTLPCPPGLKIPEEDGYTITPNTLKTLVLVGCFTVFWTIYYMLEIYLSQRNMASTQGCRSGHCPWPQRSQNSREVGTELESVPLCNSKDQDGVDSENGSCTATSTFLTPELLRERDWNLSQSSKSILDCPQHQPPDLLQGKDGQIC", "length": 787 }, "evidence": [ { "id": "A0A4X1SX84", "url": "https://omabrowser.org/oma/group/A0A4X1SX84/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q16549-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "PCSK7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKGRQKVPHLDAPLGLPTCLWLELAGLFLLVPWVMGLAGTGGPDGQGTGGPSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEAIRQQVEAVLAGHEAVRWHSEQRLLRRAKRSVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATRYEDRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKENKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDESFQVGILRQWQLTLYGSVWSAVDIRDRQRLLESAMSGKYLHDDFALPCPPGLKIPEEDGYTITPNTLKTLVLVGCFTVFWTVYYMLEVYLSQRNVASNQVCRSGPCHWPHRSRKAKEEGTELESVPLCSSKDPDEVETESRGPPTTSDLLAPDLLEQGDWSLSQNKSALDCPHQHLDVPHGKEEQIC", "length": 785 }, "evidence": [ { "id": "A0A4X1SX84", "url": "https://omabrowser.org/oma/group/A0A4X1SX84/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61139-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "Pcsk7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKGRQKVPHLDAHLGLPICLWLELAIFFLVPQVMGLSEAGGLDILGTGGLSWAVHLDSLEGERKEESLTQQADAVAQAAGLVNAGRIGELQGHYLFVQPTGHRQAMEVEAMRQQAEAVLARHEAVRWHSEQTLLKRAKRSIHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTVQDIAPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVMAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTAIQYEDHHADWLTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPMLKENKAVPRSPHSLEVLWNVSRTDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNAWTFSTVRCWGERARGVYRLVIRDVGDEPLQMGILQQWQLTLYGSMWSPVDIKDRQSLLESAMSGKYLHDGFTLPCPPGLKIPEEDGYTITPNTLKTLVLVGCFSVFWTIYYMLEVCLSQRNKASTHGCRKGCCPWAPRRQNSKDAGTALESMPLCSSKDLDGVDSEHGDCTTASSFLAPELDCPPHQPPDLLQGKSGQIC", "length": 770 }, "evidence": [ { "id": "A0A4X1SX84", "url": "https://omabrowser.org/oma/group/A0A4X1SX84/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62849-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "Pcsk7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGRQKVPRLDARLGLPICLCLELAIFFLVPQVMGLTEAGGLDTLGAGGLSWAVHLDSLEGERKEESLIQQANAVAQAAGLVNAGRIGELQGHYLFVQPAGHGQAMEAEAMRQQAEAVLAKHEAVRWHSEQRLLKRAKRSIHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTVQDIAPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVMAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATQYEDHRADWLTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPMLKENKAVPRSPHSLEVLWNVSRTDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGVYRLVIRDVGDEPLQVGILQQWQLTLYGSTWSPVDIKDRQSLLESAMSGKYLHDDFTLPCPPGLKIPEEDGYSITPNTLKTLVLVGCFSVFWTIYYMLEVCLSQRSKASTHGCRRGCCPWPPQSQNSKEVGTALESMPLCSSKDLDGVDSEHGDCTTASSLLAPELLGEADWSLSQNSKSDLDCPPHQPPDLKDGQIC", "length": 783 }, "evidence": [ { "id": "A0A4X1SX84", "url": "https://omabrowser.org/oma/group/A0A4X1SX84/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SX84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SX84" }, { "id": "PS51829", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51829" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "P/Homo B", "eco_id": "ECO_0000259", "start_pos": 481, "end_pos": 618, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 531 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 175, "end_pos": 177 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 511, "end_pos": 513 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SXF6-1", "uniprot_ac": "A0A4X1SXF6", "uniprot_id": "A0A4X1SXF6_PIG", "mass": { "chemical_mass": 50369.0, "monoisotopic_mass": 50369.0 }, "refseq": { "ac": "XP_003355948", "name": "acid phosphatase type 7 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355948" }, "gene_names": [ { "name": "ACP7", "type": "recommended", "evidence": [ { "id": "A0A4X1SXF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6" } ] }, { "name": "ACP7", "type": "synonym", "evidence": [ { "id": "XP_003355948", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355948" } ] } ], "protein_names": [ { "name": "Purple acid phosphatase", "type": "recommended", "evidence": [ { "id": "A0A4X1SXF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.2", "type": "synonym", "evidence": [ { "id": "A0A4X1SXF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6/entry#names_and_taxonomy" } ] }, { "name": "acid phosphatase type 7 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003355948", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355948" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SXF6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ACP7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6", "locus": { "chromosome": "6", "start_pos": 47859834, "end_pos": 47840213, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002971", "url": "https://www.ensembl.org/id/ENSSSCG00000002971" } ] } } ], "crossref": [ { "id": "A0A4X1SXF6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SXF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002971", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002971", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00839", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00839", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100621910", "url": "https://www.ncbi.nlm.nih.gov/gene/100621910", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041792", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041792", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621910", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621910", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SXF6", "url": "https://www.orthodb.org/?gene=A0A4X1SXF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45867", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45867", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45867:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45867:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16656", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16656", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003355948", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355948", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15017", "url": "https://www.rhea-db.org/rhea/15017", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SXF6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SXF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RI33", "url": "https://www.uniprot.org/uniprotkb/F1RI33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RI33-1", "url": "https://www.uniprot.org/uniprotkb/F1RI33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCCLRPCWSCCCLLLFFSLGVQGSLNPSAAPEQVHLSYPGEPGSMTVTWTTWVPTPSEVQFGLQLSGPLPFRAQGTVSPFVDGGILRRKLYIHRVTLQKLLPGVQYVYRCGSAQGWSRRFRFRALKNGPHWSPRLAVFGDLGADNPKALPRLRRDTQQGMYDAVLHVGDFAYNMDEDNARVGDRFMRLIEPVAASLPYMTCPGNHEERYNFSNYKARFSMPGDNQGLWYSWDLGPAHIISFSTEVYFFLHYGHHLVERQFHWLERDLQKANKNRAARPWIITMGHRPMYCSNADLDDCTWHESKVRKGLLGKLYGLEDLFYKYGVDLQLWAHEHSYERLWPIYNYQVFNGSQETPYTNPRGPVHIITGSAGCEERLTAFTLFPRPWSAVRVKEYGYTRLHILNGTHVHIQQVSDDQDGKIVDDVWVVRPLLGRMMYH", "length": 437, "header": "tr|A0A4X1SXF6-1|A0A4X1SXF6_PIG Isoform 1 of Purple acid phosphatase OS=Sus scrofa OX=9823 GN=ACP7 PE=3 SV=1 CANONICAL=A0A4X1SXF6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SXF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6/entry#A0A4X1SXF6-1", "sequence": { "sequence": "MCCLRPCWSCCCLLLFFSLGVQGSLNPSAAPEQVHLSYPGEPGSMTVTWTTWVPTPSEVQFGLQLSGPLPFRAQGTVSPFVDGGILRRKLYIHRVTLQKLLPGVQYVYRCGSAQGWSRRFRFRALKNGPHWSPRLAVFGDLGADNPKALPRLRRDTQQGMYDAVLHVGDFAYNMDEDNARVGDRFMRLIEPVAASLPYMTCPGNHEERYNFSNYKARFSMPGDNQGLWYSWDLGPAHIISFSTEVYFFLHYGHHLVERQFHWLERDLQKANKNRAARPWIITMGHRPMYCSNADLDDCTWHESKVRKGLLGKLYGLEDLFYKYGVDLQLWAHEHSYERLWPIYNYQVFNGSQETPYTNPRGPVHIITGSAGCEERLTAFTLFPRPWSAVRVKEYGYTRLHILNGTHVHIQQVSDDQDGKIVDDVWVVRPLLGRMMYH", "length": 437, "header": "tr|A0A4X1SXF6-1|A0A4X1SXF6_PIG Isoform 1 of Purple acid phosphatase OS=Sus scrofa OX=9823 GN=ACP7 PE=3 SV=1 CANONICAL=A0A4X1SXF6-1" }, "locus": { "chromosome": "6", "start_pos": 47858830, "end_pos": 47841114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077807.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077807.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069970.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069970.1" } ] } }, { "isoform_ac": "F1RI33-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6/entry#F1RI33-1", "sequence": { "sequence": "MCCLRPCWSCCCLLLFFSLGVQGSLNPSAAPEQVHLSYPGEPGSMTVTWTTWVPTPSEVQFGLQLSGPLPFRAQGTVSPFVDGGILRRKLYIHRVTLQKLLPGVQYVYRCGSAQGWSRRFRFRALKNGPHWSPRLAVFGDLGADNPKALPRLRRDTQQGMYDAVLHVATSPTTRLASACQGTTKACGTAGTWARHTSSPSPPRCISSSITATTWWRDSFIGWRGTSRKPIRTGQPGPGSLPWVTGPCTVPMPIWMTVPGMKARFAKASWANYMDWRIFSTNTGSTCSCGLTSTRMNVCGRFTTTRYLTAAKRRPTPTLGAPSTSSPDLPTGRLS", "length": 334, "header": "tr|F1RI33-1|A0A4X1SXF6_PIG Computationally mapped isoform of Purple acid phosphatase OS=Sus scrofa OX=9823 GN=ACP7 PE=3 SV=4 CANONICAL=A0A4X1SXF6-1" }, "locus": { "chromosome": "6", "start_pos": 47858783, "end_pos": 47841114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003296.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003296.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003214.4", "url": "https://www.ensembl.org/id/ENSSSCP00000003214.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RI33", "url": "https://www.uniprot.org/uniprotkb/F1RI33" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621910", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621910", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SXF6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6" } ], "pmid": "" }, { "name": "acid phosphatase activity", "id": "GO:0003993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003993", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SXF6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15017", "name": "", "equation": "a phosphate monoester + H2O = an alcohol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "15017", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15017" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SXF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6" }, { "id": "PF00149", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calcineurin-like phosphoesterase", "eco_id": "ECO_0000259", "start_pos": 134, "end_pos": 336, "start_aa": "Arg", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SXF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6" }, { "id": "PF14008", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14008" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Purple acid phosphatase C-terminal", "eco_id": "ECO_0000259", "start_pos": 361, "end_pos": 422, "start_aa": "Gly", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SXF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXF6" }, { "id": "PF16656", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16656" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Purple acid phosphatase N-terminal", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 123, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 55 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 403, "end_pos": 405 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SXK8-1", "uniprot_ac": "A0A4X1SXK8", "uniprot_id": "A0A4X1SXK8_PIG", "mass": { "chemical_mass": 20943.0, "monoisotopic_mass": 20943.0 }, "refseq": { "ac": "XP_020936213", "name": "protein SSX1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936213" }, "gene_names": [ { "name": "LOC100627608", "type": "synonym", "evidence": [ { "id": "XP_020936213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936213" } ] } ], "protein_names": [ { "name": "KRAB-related domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A4X1SXK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXK8/entry#names_and_taxonomy" } ] }, { "name": "protein SSX1-like", "type": "synonym", "evidence": [ { "id": "XP_020936213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936213" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SXK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXK8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXK8", "locus": {} } ], "crossref": [ { "id": "A0A4X1SXK8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SXK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100627608", "url": "https://www.ncbi.nlm.nih.gov/gene/100627608", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100627608", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627608", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SXK8", "url": "https://www.orthodb.org/?gene=A0A4X1SXK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14112:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14112:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020936213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936213", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SXK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SXK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SZD4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SZD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRGSYFAQRAREDAQKSEKKSKAFNDISKYFSKEEWAKLGYSEKITYVYMKRNYDTMTGLGLKATPPTFMCPRKQTIESSGHDSEDQDEPPKEASNLRGRKYLEVMPKTPEKEKNLLELGPTTSGSEKAPSEPCLLGKASASAQQSKETSGSGRSKINVWTHRLRERKYPVIYEEISDPEEDD", "length": 184, "header": "tr|A0A4X1SXK8-1|A0A4X1SXK8_PIG Isoform 1 of KRAB-related domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A4X1SXK8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SXK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXK8/entry#A0A4X1SXK8-1", "sequence": { "sequence": "MNRGSYFAQRAREDAQKSEKKSKAFNDISKYFSKEEWAKLGYSEKITYVYMKRNYDTMTGLGLKATPPTFMCPRKQTIESSGHDSEDQDEPPKEASNLRGRKYLEVMPKTPEKEKNLLELGPTTSGSEKAPSEPCLLGKASASAQQSKETSGSGRSKINVWTHRLRERKYPVIYEEISDPEEDD", "length": 184, "header": "tr|A0A4X1SXK8-1|A0A4X1SXK8_PIG Isoform 1 of KRAB-related domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A4X1SXK8-1" }, "locus": { "chromosome": "X", "start_pos": 42566866, "end_pos": 42559777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081676.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081676.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063895.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063895.1" } ] } }, { "isoform_ac": "A0A4X1SZD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXK8/entry#A0A4X1SZD4-1", "sequence": { "sequence": "MNRGSYFAQRAREDAQKSEKKSKAFNDISKYFSKEEWAKLGYSEKITYVYMKRNYDTMTGLGLKATPPTFMCPRKQTIESSGHDSEDQDEPPKEASNLRGRKYLEDPGEARLMSGPTDCGKESTQSMKRSAIPRKMTNSPQRCDKCP", "length": 147, "header": "tr|A0A4X1SZD4-1|A0A4X1SZD4_PIG Computationally mapped isoform of KRAB-related domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A4X1SXK8-1" }, "locus": { "chromosome": "X", "start_pos": 42567482, "end_pos": 42559777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091221.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091221.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066150.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066150.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SXK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXK8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100627608", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627608", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SXK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SXK8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SXK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXK8" }, { "id": "PS50806", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50806" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB-related", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 84, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SY72-1", "uniprot_ac": "A0A4X1SY72", "uniprot_id": "A0A4X1SY72_PIG", "mass": { "chemical_mass": 42153.0, "monoisotopic_mass": 42153.0 }, "refseq": { "ac": "XP_005662060", "name": "protein-tyrosine sulfotransferase 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005662060" }, "gene_names": [ { "name": "TPST1", "type": "recommended", "evidence": [ { "id": "A0A4X1SY72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72" } ] }, { "name": "TPST1", "type": "synonym", "evidence": [ { "id": "XP_005662060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005662060" } ] } ], "protein_names": [ { "name": "Protein-tyrosine sulfotransferase", "type": "recommended", "evidence": [ { "id": "A0A4X1SY72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.20", "type": "synonym", "evidence": [ { "id": "A0A4X1SY72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72/entry#names_and_taxonomy" } ] }, { "name": "protein-tyrosine sulfotransferase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005662060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005662060" } ] } ], "function": [ { "annotation": "Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SY72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72#function" }, { "database": "UniProtKB", "id": "ARBA00003886", "url": "https://www.uniprot.org/uniprotkb/ARBA00003886#function" }, { "database": "UniProtKB", "id": "RU365018", "url": "https://www.uniprot.org/uniprotkb/RU365018#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SY72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TPST1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72", "locus": { "chromosome": "3", "start_pos": 16407609, "end_pos": 16585485, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007737", "url": "https://www.ensembl.org/id/ENSSSCG00000007737" } ] } } ], "crossref": [ { "id": "A0A4X1SY72", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SY72", "database": "AlphaFoldDB", "categories": [] }, { "id": "100517581", "url": "https://www.ncbi.nlm.nih.gov/gene/100517581", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SQWKKSE", "url": "https://omabrowser.org/oma/group/SQWKKSE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SY72", "url": "https://www.orthodb.org/?gene=A0A4X1SY72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12788", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12788", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12788:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12788:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156584", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156584", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005662060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005662060", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16801", "url": "https://www.rhea-db.org/rhea/16801", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SY72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SY72-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPLRLESAKTTVPTVLDIKANKTFAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRRVYKGEFQLPEFLKEKPQTEQVE", "length": 370, "header": "tr|A0A4X1SY72-1|A0A4X1SY72_PIG Isoform 1 of Protein-tyrosine sulfotransferase OS=Sus scrofa OX=9823 GN=TPST1 PE=3 SV=1 CANONICAL=A0A4X1SY72-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SY72-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72/entry#A0A4X1SY72-1", "sequence": { "sequence": "MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPLRLESAKTTVPTVLDIKANKTFAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRRVYKGEFQLPEFLKEKPQTEQVE", "length": 370, "header": "tr|A0A4X1SY72-1|A0A4X1SY72_PIG Isoform 1 of Protein-tyrosine sulfotransferase OS=Sus scrofa OX=9823 GN=TPST1 PE=3 SV=1 CANONICAL=A0A4X1SY72-1" }, "locus": { "chromosome": "3", "start_pos": 16487812, "end_pos": 16410350, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063892.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063892.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058859.1", "url": "https://www.ensembl.org/id/ENSSSCP00000058859.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SY72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156584", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156584", "resource": "Reactome", "description": "Cytosolic sulfonation of small molecules" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1ANA1-1", "protein_name": "Protein-tyrosine sulfotransferase", "gene_name": "TPST1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARVESVRSTVRTGSDGNANKTFAYNKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILAVKQMWARSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLARIFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGFERCMLVHYEQLVLHPERWMRTLLKFLRIPWNQAVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVEALSKWVGKIPADVLQDMPVIAPMLAKLGYDPYANPPNYGKPDQKVVENTRRDDQQSRVPQYHRIVEWPALKRTTMTIQFQPSAVCRVTNHWTRAAQSHIQPGLECLQGWGILSLCLIAHLVGIASSLEIPNCTAFLWSYGFCFALFFTSSTAVCLLRHKAVGKQGVR", "length": 464 }, "evidence": [ { "id": "A0A4X1SY72", "url": "https://omabrowser.org/oma/group/A0A4X1SY72/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O60507-1", "protein_name": "Protein-tyrosine sulfotransferase 1", "gene_name": "TPST1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLDLKANKTFAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRVYKGEFQLPDFLKEKPQTEQVE", "length": 370 }, "evidence": [ { "id": "A0A4X1SY72", "url": "https://omabrowser.org/oma/group/A0A4X1SY72/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70281-1", "protein_name": "Protein-tyrosine sulfotransferase 1", "gene_name": "Tpst1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRAGLDIKANKTFTYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRRVYKGEFQLPDFLKEKPQTEQVE", "length": 370 }, "evidence": [ { "id": "A0A4X1SY72", "url": "https://omabrowser.org/oma/group/A0A4X1SY72/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9PTE6-1", "protein_name": "Protein-tyrosine sulfotransferase 1", "gene_name": "tpst1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIGKLKQNLLVACLVISSVTVFYLCRHAMDCHHRIEERSQPLLSSLHATLRTGQNLSTPFIYNKDMPLIFIGGVPRSGTTLMRAMLDAHPDVRCGEETRVIPRILAMKQMWSRSGREKMRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPANYLCNKDPFALKSLTYLAKIFPHAKFILMVRDGRASVHSMISRKVTIAGFDLSSYRDCLTKWNRAIETMYTQCLEAADKCLPVHYEQLVLHPEKWMRTLLRFLNIPWNDAVLHHEELIGKAGGVSLSKVERSTDQVIKPVNVEALSKWVGKIPLDVQRDMAVIAPMLARLGYDPHANPPNYGRPDPLVLDNTRRLQKSPEKPNPS", "length": 355 }, "evidence": [ { "id": "A0A4X1SY72", "url": "https://omabrowser.org/oma/group/A0A4X1SY72/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SY72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SY72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72" } ], "pmid": "" }, { "name": "Golgi lumen", "id": "GO:0005796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005796", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SY72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SY72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SY72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72" } ], "pmid": "" }, { "name": "protein-tyrosine sulfotransferase activity", "id": "GO:0008476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008476", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SY72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "post-translational protein modification", "id": "GO:0043687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043687", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SY72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16801", "name": "", "equation": "L-tyrosyl-[protein] + 3'-phosphoadenylyl sulfate = O-sulfo-L-tyrosine-[protein] + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16801" } ] }, { "id": "R-SSC-8954262", "name": "TPST1,2 transfer SO4(2-) from PAPS to PODXL2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-SSC-8954248" ], "output_participant_list": [ "R-SSC-8954273" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8954262", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8954262" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-8954248", "participant_name": "PODXL2 [Golgi lumen]", "crossref": [ { "id": "I3L7V6", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000021397", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000020114", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000024591", "database": "ENSEMBL", "url": "" }, { "id": "91619", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-8954273", "participant_name": "PODXL2 [Golgi lumen]", "crossref": [ { "id": "ENSSSCG00000021397", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000024591", "database": "ENSEMBL", "url": "" }, { "id": "I3L7V6", "database": "UniProt", "url": "" }, { "id": "91619", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000020114", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 262, "end_pos": 264 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SYF7-1", "uniprot_ac": "A0A4X1SYF7", "uniprot_id": "A0A4X1SYF7_PIG", "mass": { "chemical_mass": 88684.0, "monoisotopic_mass": 88684.0 }, "refseq": { "ac": "XP_020955243", "name": "protein sel-1 homolog 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955243" }, "gene_names": [ { "name": "SEL1L", "type": "recommended", "evidence": [ { "id": "A0A4X1SYF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7" } ] }, { "name": "SEL1L", "type": "synonym", "evidence": [ { "id": "XP_020955243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955243" } ] } ], "protein_names": [ { "name": "Protein sel-1 homolog 1", "type": "recommended", "evidence": [ { "id": "A0A4X1SYF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7/entry#names_and_taxonomy" } ] }, { "name": "Suppressor of lin-12-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A4X1SYF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7/entry#names_and_taxonomy" } ] }, { "name": "protein sel-1 homolog 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020955243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955243" } ] } ], "function": [ { "annotation": "Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLF0#function" }, { "database": "UniProtKB", "id": "ARBA00054921", "url": "https://www.uniprot.org/uniprotkb/ARBA00054921#function" }, { "database": "UniProtKB", "id": "A0A4X1SYF7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7#function" }, { "database": "UniProtKB", "id": "A0A8W4FJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJM9#function" }, { "database": "UniProtKB", "id": "F1SDZ8", "url": "https://www.uniprot.org/uniprotkb/F1SDZ8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYF7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SEL1L", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7", "locus": { "chromosome": "7", "start_pos": 104219411, "end_pos": 104283195, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002414", "url": "https://www.ensembl.org/id/ENSSSCG00000002414" } ] } } ], "crossref": [ { "id": "A0A4X1SYF7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SYF7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002414", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002414", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00062", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00062", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100520751", "url": "https://www.ncbi.nlm.nih.gov/gene/100520751", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520751", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520751", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LLGHWMD", "url": "https://omabrowser.org/oma/group/LLGHWMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SYF7", "url": "https://www.orthodb.org/?gene=A0A4X1SYF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11102", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11102", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11102:SF70", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11102:SF70", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00040", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00040", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-382556", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-382556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5358346", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358346", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9931269", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9931269", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020955243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955243", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SYF7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SYF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QE71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QE71-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SDZ8", "url": "https://www.uniprot.org/uniprotkb/F1SDZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SDZ8-1", "url": "https://www.uniprot.org/uniprotkb/F1SDZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVGVRLTLLLCVVLLGSASVSSDEEGDQDESLDSKTSLPSDESVKDHSPTGRVVAGQLFLESEESEVESPIQEEEDSLRSQEGESVAEEINFLESPNPENRDYEEPTKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLSQNIQAAKGMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTHLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPVPRPPGPRPAPPQQEGPPEQQAPQ", "length": 794, "header": "tr|A0A4X1SYF7-1|A0A4X1SYF7_PIG Isoform 1 of Protein sel-1 homolog 1 OS=Sus scrofa OX=9823 GN=SEL1L PE=1 SV=1 CANONICAL=A0A4X1SYF7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SYF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7/entry#A0A4X1SYF7-1", "sequence": { "sequence": "MRVGVRLTLLLCVVLLGSASVSSDEEGDQDESLDSKTSLPSDESVKDHSPTGRVVAGQLFLESEESEVESPIQEEEDSLRSQEGESVAEEINFLESPNPENRDYEEPTKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLSQNIQAAKGMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTHLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPVPRPPGPRPAPPQQEGPPEQQAPQ", "length": 794, "header": "tr|A0A4X1SYF7-1|A0A4X1SYF7_PIG Isoform 1 of Protein sel-1 homolog 1 OS=Sus scrofa OX=9823 GN=SEL1L PE=1 SV=1 CANONICAL=A0A4X1SYF7-1" }, "locus": { "chromosome": "7", "start_pos": 104283077, "end_pos": 104223632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049435.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049435.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038539.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038539.1" } ] } }, { "isoform_ac": "A0A5G2QE71-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7/entry#A0A5G2QE71-1", "sequence": { "sequence": "MRVGVRLTLLLCVVLLGSASVSSDEEGDQDESLDSKTSLPSDESVKDHSPTGRVVAGQLFLESEESEVESPIQEEEDSLRSQEGESVAEEINFLESPNPENRDYEEPTKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLSQNIQAAKGMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLVSRLK", "length": 302, "header": "tr|A0A5G2QE71-1|A0A4X1SYF7_PIG Computationally mapped isoform of Protein sel-1 homolog 1 OS=Sus scrofa OX=9823 GN=SEL1L PE=1 SV=1 CANONICAL=A0A4X1SYF7-1" }, "locus": { "chromosome": "7", "start_pos": 104283077, "end_pos": 104250972, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085937.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085937.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061952.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061952.1" } ] } }, { "isoform_ac": "A0A5G2RLF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7/entry#A0A5G2RLF0-1", "sequence": { "sequence": "MKSLETSLPSDESVKDHSPTGRVVAGQLFLESEESEVESPIQEEEDSLRSQEGESVAEEINFLESPNPENRDYEEPTKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCESNLLFSTLVQEAFAYRYLQKAAGMNHTKALERVSYALLFGDYLSQNIQAAKGMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTHLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPVPRPPGPRPAPPQQEGPPEQQAPQ", "length": 740, "header": "tr|A0A5G2RLF0-1|A0A4X1SYF7_PIG Computationally mapped isoform of Protein sel-1 homolog 1 OS=Sus scrofa OX=9823 GN=SEL1L PE=1 SV=2 CANONICAL=A0A4X1SYF7-1" }, "locus": { "chromosome": "7", "start_pos": 104277097, "end_pos": 104223632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089522.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089522.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073128.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073128.1" } ] } }, { "isoform_ac": "A0A8W4FJM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7/entry#A0A8W4FJM9-1", "sequence": { "sequence": "MKSLETSLPSDESVKDHSPTGRVVAGQLFLESEESEVESPIQEEEDSLRSQEGESVAEEINFLESPNPENRDYEEPTKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCESKCSSVQEACLAYRYLQKAAGMNHTKALERVSYALLFGDYLSQNIQAAKGMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTHLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPVPRPPGPRPAPPQQEGPPEQQAPQ", "length": 738, "header": "tr|A0A8W4FJM9-1|A0A4X1SYF7_PIG Computationally mapped isoform of Protein sel-1 homolog 1 OS=Sus scrofa OX=9823 GN=SEL1L PE=1 SV=2 CANONICAL=A0A4X1SYF7-1" }, "locus": { "chromosome": "7", "start_pos": 104277097, "end_pos": 104223632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092548.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092548.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079426.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079426.1" } ] } }, { "isoform_ac": "F1SDZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7/entry#F1SDZ8-1", "sequence": { "sequence": "MRVGVRLTLLLCVVLLGSASVSSDSQTSLPSDESVKDHSPTGRVVAGQLFLESEESEVESPIQEEEDSLRSQEGESVAEEINFLESPNPENRDYEEPTKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLSQNIQAAKGMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTHLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPVPRPPGPRPAPPQQEGPPEQQAPQ", "length": 784, "header": "tr|F1SDZ8-1|F1SDZ8_PIG Computationally mapped isoform of Protein sel-1 homolog 1 OS=Sus scrofa OX=9823 GN=SEL1L PE=1 SV=3 CANONICAL=A0A4X1SYF7-1" }, "locus": { "chromosome": "7", "start_pos": 104283077, "end_pos": 104223632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002683.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002683.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002616.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002616.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QE71", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE71" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520751", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520751", "resource": "KEGG Pathway" }, { "id": "R-SSC-382556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-382556", "resource": "Reactome", "description": "ABC-family protein mediated transport" }, { "id": "R-SSC-5358346", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358346", "resource": "Reactome", "description": "Hedgehog ligand biogenesis" }, { "id": "R-SSC-9931269", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9931269", "resource": "Reactome", "description": "AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MGJ5-1", "protein_name": "Protein sel-1 homolog 1", "gene_name": "SEL1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRVWVGLTLLLWAVLLGSALASSDEEGNQDESVDSKTSVPSDESVENHSPASRVIAGQIFLDSEESELESPPQEEEGNLRSQEGESIAEEISFLESPNPENKDYEELTKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAARRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVSYALLFGDYLTQNIQAAKEMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYSSYKDGDSNAAVIQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDIFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPVPRPPGPRPAPPQQEGPPEQPPLQ", "length": 794 }, "evidence": [ { "id": "A0A4X1SYF7", "url": "https://omabrowser.org/oma/group/A0A4X1SYF7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q05787-1", "protein_name": "ERAD-associated E3 ubiquitin-protein ligase component HRD3", "gene_name": "HRD3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MITLLLYLCVICNAIVLIRADSIADPWPEARHLLNTIAKSRDPMKEAAMEPNADEFVGFYVPMDYSPRNEEKNYQSIWQNEITDSQRHIYELLVQSSEQFNNSEATYTLSQIHLWSQYNFPHNMTLAHKYLEKFNDLTHFTNHSAIFDLAVMYATGGCASGNDQTVIPQDSAKALLYYQRAAQLGNLKAKQVLAYKYYSGFNVPRNFHKSLVLYRDIAEQLRKSYSRDEWDIVFPYWESYNVRISDFESGLLGKGLNSVPSSTVRKRTTRPDIGSPFIAQVNGVQMTLQIEPMGRFAFNGNDGNINGDEDDEDASERRIIRIYYAALNDYKGTYSQSRNCERAKNLLELTYKEFQPHVDNLDPLQVFYYVRCLQLLGHMYFTGEGSSKPNIHMAEEILTTSLEISRRAQGPIGRACIDLGLINQYITNNISQAISYYMKAMKTQANNGIVEFQLSKLATSFPEEKIGDPFNLMETAYLNGFIPAIYEFAVMIESGMNSKSSVENTAYLFKTFVDKNEAIMAPKLRTAFAALINDRSEVALWAYSQLAEQGYETAQVSAAYLMYQLPYEFEDPPRTTDQRKTLAISYYTRAFKQGNIDAGVVAGDIYFQMQNYSKAMALYQGAALKYSIQAIWNLGYMHEHGLGVNRDFHLAKRYYDQVSEHDHRFYLASKLSVLKLHLKSWLTWITREKVNYWKPSSPLNPNEDTQHSKTSWYKQLTKILQRMRHKEDSDKAAEDSHKHRTVVQNGANHRGDDQEEASEILGFQMEDLVTMGCILGIFLLSILMSTLAARRGWNVRFNGAQLNANGNRQQEQQQQQQAQGPPGWDFNVQIFAI", "length": 833 }, "evidence": [ { "id": "A0A4X1SYF7", "url": "https://omabrowser.org/oma/group/A0A4X1SYF7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5RIK6-1", "protein_name": "Protein sel-1 homolog 1", "gene_name": "sel1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSAKKSCLVLIVALAVTLEVTAGEVPSDDGVGEGGDSQSTAENEGANIVTGRAYVPKDAQTDSSTTDTDMEIKVDEIEKEDLPSQPPPPQERSKEVPVVNGGTASGEPCIFPFLFQGKEYSDCTTEGRGDGRLWCATTYDYNNDKRWGFCETEEQAEQRRMAEEAEEQYQATVRMINGTNRRSQKKELFDKLLQVAEMGHTKAMEKVAYAMLFGDYLPQSIPQAKEMFEKLALEGSPKAQTALGFLYAAGLGVNSSQAKALVYYTFGALGGNLVAHMILGYRYWGGVGVPQSCESALTHYRLVANHVASDVSLTGGSAVQRIRLLDEVENPGSSSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAYEYFNQAANAGNTHAMAFLGKMYSEGSEYVPQNNETALHYFKKAADLGNPVGQSGLGMAYLYGRGVPVNYDLALKYFQKAAEQGWVDGQLQLGTMYYNGIGVKRDYKQALKFFNLASQAGHILAFYNLAQMHATGTGVMRSCHTAVELFKNVCERGRWSERLMAAYRSFKEGDMDSALIQYLLLAEQGYEVAQSNVAFVLDQKGSQIFNENETYPRALLHWTRAAAQGYTVARIKLGDYHFYGYGTDVDYETAVIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGLVYALQYLQDLNLKEVLSQVDLDQLLGPEWDLYLMTVIALLLGTVIAYRQRQHQAVPRAPAAPNRPPAQPEQPAEEPEEQ", "length": 776 }, "evidence": [ { "id": "A0A4X1SYF7", "url": "https://omabrowser.org/oma/group/A0A4X1SYF7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80Z70-1", "protein_name": "Protein sel-1 homolog 1", "gene_name": "Sel1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQVRVRLLLLLCAVLLGSAAASSDEETNQDESLDSKGALPTDGSVKDHTTGKVVLLARDLLILKDSEVESLLQDEEESSKSQEEVSVTEDISFLDSPNPSSKTYEELKRVRKPVLTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKTDEKWGFCETEEDAAKRRQMQEAEAIYQSGMKILNGSTRKNQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNIQAAKEMFEKLTEEGSPKGQTGLGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDDDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIREANIRDLFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDIPVPRPPGPRPAPPQQEGPPEQQPPQ", "length": 794 }, "evidence": [ { "id": "A0A4X1SYF7", "url": "https://omabrowser.org/oma/group/A0A4X1SYF7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9LM25-1", "protein_name": "ERAD-associated E3 ubiquitin-protein ligase component HRD3A", "gene_name": "HRD3A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRILSYGIVILSLLVFSFIEFGVHARPVVLVLSNDDLNSGGDDNGVGESSDFDEFGESEPKSEEELDPGSWRSIFEPDDSTVQAASPQYYSGLKKILSAASEGNFRLMEEAVDEIEAASSAGDPHAQSIMGFVYGIGMMREKSKSKSFLHHNFAAAGGNMQSKMALAFTYLRQDMHDKAVQLYAELAETAVNSFLISKDSPVVEPTRIHSGTEENKGALRKSRGEEDEDFQILEYQAQKGNANAMYKIGLFYYFGLRGLRRDHTKALHWFLKAVDKGEPRSMELLGEIYARGAGVERNYTKALEWLTLAAKEGLYSAFNGIGYLYVKGYGVDKKNYTKAREYFEKAVDNEDPSGHYNLGVLYLKGIGVNRDVRQATKYFFVAANAGQPKAFYQLAKMFHTGVGLKKNLEMATSFYKLVAERGPWSSLSRWALEAYLKGDVGKALILYSRMAEMGYEVAQSNAAWILDKYGERSMCMGVSGFCTDKERHERAHSLWWRASEQGNEHAALLIGDAYYYGRGTERDFVRAAEAYMHAKSQSNAQAMFNLGYMHEHGQGLPFDLHLAKRYYDESLQSDAAARLPVTLALASLWLRRNYADTVLVRVVDSLPEVYPKVETWIENVVFEEGNATILTLFVCLITILYLRERQRRQVVVVADPVAADVAQPLDADVAQHLAAFPR", "length": 678 }, "evidence": [ { "id": "A0A4X1SYF7", "url": "https://omabrowser.org/oma/group/A0A4X1SYF7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UBV2-1", "protein_name": "Protein sel-1 homolog 1", "gene_name": "SEL1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVRIGLTLLLCAVLLSLASASSDEEGSQDESLDSKTTLTSDESVKDHTTAGRVVAGQIFLDSEESELESSIQEEEDSLKSQEGESVTEDISFLESPNPENKDYEEPKKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVSYALLFGDYLPQNIQAAREMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVIQYLLLAEQGYEVAQSNAAFILDQREASIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPAPRPPGPRPAPPQQEGPPEQQPPQ", "length": 794 }, "evidence": [ { "id": "A0A4X1SYF7", "url": "https://omabrowser.org/oma/group/A0A4X1SYF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V415-1", "protein_name": "HMG-coA reductase degradation 3, isoform B", "gene_name": "Hrd3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKANSWMCLLALLLAWQLRAEELQGPNIDGTGSSLGSATGTGTGTGLGTGTATPTLPNEPSTQAEAEEVTTAESESRVPSESNERKADKPKESTKFASRTKVMPASLFERLWNESLIRRQKLKAEIERIEAKRKSTEVLELTPDQIEAQTVYDNAMDMLAKPSTDKRVAMILLKKAAAFNHLKARAELAWAALLGQWMDFDFNHAVDEFESLANEGVPEAHMGLGFLYSVGVGGKNVSQPLALIHYSLAALGDNTPAQMAMGYRYLYGINVPISCEKALIHYKRVAKKVASKITFANGPVVHRVRLLDDLENPGSSETEIVDYYKLLADKGDIQSQVGLGQVYYQGGKVTEQDHQKALEYFKMAADAGSAVGIAFLGKLYLEGSDQIRADNDAAFGYFSKAAEMGDPVGQSGLGLMYLKGLGVPKDSIKALSYFTQAADQGWVDGQLQLGNMYFTGNGVKTDYKLAFKYFNLATQSGHVLAYYNLGVMNAYGMGMLRSCPAAVEFFKTVSERGRWSSRLMMAYSDYKNNRIDEAYMQYSLMAEMGYEVAQSNAAFLLDRKEVHVFNDRHEDLIRAFYYWKRAAGQGYSAAQVKLGDYYYYGWGTSTDFETAAALYRKASEQQYNAQAMFNLGYMHEQGLGMKKDWHLAKRLYDLAAETNSDAKVPVAIALFKLQMLATIESIKESPYRFIFYMDENIAANWDLYMITVLTLLLGIIMYMRRPFQQPDQPAQQPAADDIAAAPVNLAPVGAEAAPVAAVVEGVGVTPPAAAVSSHDAVAASSSTETSSTTATSLVDAASQGGSGTTSAAPDGANTLDPTG", "length": 819 }, "evidence": [ { "id": "A0A4X1SYF7", "url": "https://omabrowser.org/oma/group/A0A4X1SYF7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z2G6-1", "protein_name": "Protein sel-1 homolog 1", "gene_name": "Sel1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQVRVRLSLLLLCAVLLGSAAATSDDKTNQDDSLDSKSSLPTDESVKDHTTTGKVVAGQIFVDSEEAEVESLLQDEEDSSKTQEEEISFLESPNPSSKTYEELKRVRKPVLTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKTDEKWGFCETEEDAAKRRQMQEAEMIYQAGMKILNGSNRKSQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNIQAAKEMFEKLTEEGSPKGQTGLGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMILGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDEDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIREANIRDLFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDIPVPRPPGPRPAPPQQEGPPEQQPPQ", "length": 790 }, "evidence": [ { "id": "A0A4X1SYF7", "url": "https://omabrowser.org/oma/group/A0A4X1SYF7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "triglyceride metabolic process", "id": "GO:0006641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006641", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYF7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYF7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7" } ], "pmid": "" }, { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYF7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYF7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7" } ], "pmid": "" }, { "name": "retrograde protein transport, ER to cytosol", "id": "GO:0030970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030970", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYF7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYF7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYF7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7" } ], "pmid": "" }, { "name": "Derlin-1 retrotranslocation complex", "id": "GO:0036513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036513", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYF7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7" } ], "pmid": "" }, { "name": "Hrd1p ubiquitin ligase ERAD-L complex", "id": "GO:0000839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000839", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYF7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 608, "end_pos": 610, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SYF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYF7" }, { "id": "PS51092", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51092" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-II", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 170, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { "start_pos": 217, "end_pos": 219 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 431, "end_pos": 433 }, { "start_pos": 608, "end_pos": 610 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SYL5-1", "uniprot_ac": "A0A4X1SYL5", "uniprot_id": "A0A4X1SYL5_PIG", "mass": { "chemical_mass": 76022.0, "monoisotopic_mass": 76022.0 }, "refseq": { "ac": "XP_020935774", "name": "cyclic nucleotide-gated olfactory channel", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935774" }, "gene_names": [ { "name": "CNGA2", "type": "recommended", "evidence": [ { "id": "A0A4X1SYL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ] }, { "name": "CNGA2", "type": "synonym", "evidence": [ { "id": "XP_020935774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935774" } ] } ], "protein_names": [ { "name": "Cyclic nucleotide-gated channel alpha-2", "type": "recommended", "evidence": [ { "id": "A0A4X1SYL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5/entry#names_and_taxonomy" } ] }, { "name": "Olfactory cyclic nucleotide-gated channel subunit 1", "type": "synonym", "evidence": [ { "id": "A0A4X1SYL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5/entry#names_and_taxonomy" } ] }, { "name": "cyclic nucleotide-gated olfactory channel", "type": "synonym", "evidence": [ { "id": "XP_020935774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935774" } ] } ], "function": [ { "annotation": "Pore-forming subunit of the olfactory cyclic nucleotide-gated channel. Operates in the cilia of olfactory sensory neurons where chemical stimulation of the odorant is converted to an electrical signal. Mediates odorant-induced cAMP-dependent Ca(2+) influx triggering neuron depolarization. The rise of intracellular Ca(2+) levels potentiates the olfactory response by activating Ca(2+)-dependent Cl(-) channels, but it also serves as a negative feedback signal to desensitize the channel for rapid adaptation to odorants. Conducts cAMP- and cGMP-gated ion currents, with permeability for monovalent and divalent cations.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5#function" }, { "database": "UniProtKB", "id": "ARBA00044728", "url": "https://www.uniprot.org/uniprotkb/ARBA00044728#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CNGA2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5", "locus": { "chromosome": "X", "start_pos": 123129840, "end_pos": 123115975, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012753", "url": "https://www.ensembl.org/id/ENSSSCG00000012753" } ] } } ], "crossref": [ { "id": "A0A4X1SYL5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SYL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00038", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00038", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156266", "url": "https://www.ncbi.nlm.nih.gov/gene/100156266", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156266", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156266", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DWYYHWL", "url": "https://omabrowser.org/oma/group/DWYYHWL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SYL5", "url": "https://www.orthodb.org/?gene=A0A4X1SYL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45638", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45638", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45638:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45638:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16526", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16526", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5620916", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020935774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935774", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "28747", "url": "https://www.rhea-db.org/rhea/28747", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78547", "url": "https://www.rhea-db.org/rhea/78547", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78551", "url": "https://www.rhea-db.org/rhea/78551", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78555", "url": "https://www.rhea-db.org/rhea/78555", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SYL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEKANGVKSSPANHNHHAPPTIKANGKDDHRTSSRPQSAADDDTSSELQRLAELDAPQRGRGGFRRIVRLVGVIRDWANKNFREEEPRPDSFLERFRGPELQTVTTQQGDGKGDKDGEGKATKKKFELFVLDPAGDWYYRWLFVIALPVLYNWCLLVARACFSDLQKGYYIAWLVLDYFSDVVYIIDLLIRLRTGFLEQGLLVRDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHRPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKEMEAKVIRWFDYLWTNKKSVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVAASMEVNVQEKLEQLETNMETLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNNEDDYLSDGMNSPEPAAAENP", "length": 663, "header": "tr|A0A4X1SYL5-1|A0A4X1SYL5_PIG Isoform 1 of Cyclic nucleotide-gated channel alpha-2 OS=Sus scrofa OX=9823 GN=CNGA2 PE=3 SV=1 CANONICAL=A0A4X1SYL5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SYL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5/entry#A0A4X1SYL5-1", "sequence": { "sequence": "MTEKANGVKSSPANHNHHAPPTIKANGKDDHRTSSRPQSAADDDTSSELQRLAELDAPQRGRGGFRRIVRLVGVIRDWANKNFREEEPRPDSFLERFRGPELQTVTTQQGDGKGDKDGEGKATKKKFELFVLDPAGDWYYRWLFVIALPVLYNWCLLVARACFSDLQKGYYIAWLVLDYFSDVVYIIDLLIRLRTGFLEQGLLVRDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHRPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKEMEAKVIRWFDYLWTNKKSVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVAASMEVNVQEKLEQLETNMETLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNNEDDYLSDGMNSPEPAAAENP", "length": 663, "header": "tr|A0A4X1SYL5-1|A0A4X1SYL5_PIG Isoform 1 of Cyclic nucleotide-gated channel alpha-2 OS=Sus scrofa OX=9823 GN=CNGA2 PE=3 SV=1 CANONICAL=A0A4X1SYL5-1" }, "locus": { "chromosome": "X", "start_pos": 123129029, "end_pos": 123124134, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013943.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013943.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013560.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013560.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156266", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156266", "resource": "KEGG Pathway" }, { "id": "R-SSC-5620916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620916", "resource": "Reactome", "description": "VxPx cargo-targeting to cilium" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YJP3-1", "protein_name": "Cyclic nucleotide gated channel subunit alpha 2", "gene_name": "CNGA2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMARSNGLQLPGPCPPLPTRARTDAQSTELSTSRTHSTQDETLELHRGTPAYGGEQLAAPPFQGRQALARIVRLVMVLRDWASKSLQEEQQRPDPFLERFQGPELQTVPADAISGPEDEEAEEKTKKKKWQSFVVDPARDWYYRWLAVIAVPVLYNWCLLVARACFSDLQKTYVVLWLVLDYISDCIYIGDIVISLRTGFLEQGLLVKDLKKLRDNYIYTLQFKLDVLSILPTDLAYFAVGLHHPELRFNRLLHFSRMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYAISKAIGFGEDSWVYPNVTDPEYGYLTREYVYCLYWSTLTLTTIGETPPPVRDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAIKHYMQFRKVSKDMETKVIKWFDYLWTNKKAVDEREVLKSLPDKLRAEIAINVHLETLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGTTQYALLTAGGCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKEDLMEVVTEYPDAKKVLEERGREILIKEGLLDESAEEESMEGKSVEEKLDRLTLNLDTLHTRLGRLLTEYSDAQMKLKQRITVLESQMRQQDLEDFFSDSSDSLSEVGGEATPAGL", "length": 671 }, "evidence": [ { "id": "A0A4X1SYL5", "url": "https://omabrowser.org/oma/group/A0A4X1SYL5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MBN0-1", "protein_name": "Cyclic nucleotide-gated channel alpha-2", "gene_name": "CNGA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTEKANGVKSSPANNHNHHAPPAIKASGKDDHRASSRPQSAADDDTSSELQRLAEMDAPQQRRGGFRRIARLVGVLREWAYRNFREEEPRPDSFLERFRGPELHTVTTQQGDGKGDKDGEGKGTKKKFELFVLDPAGDWYYRWLFLIALPVLYNWCLLVARACFSDLQKGYYIVWLVLDYVSDVVYIADLFIRLRTGFLEQGLLVKDTKKLRDNYIHTMQFKLDVASIIPTDLIYFAVGIHNPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLILYILIIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLSREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKEMEAKVIRWFDYLWTNKKSVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKRVLEERGREILMKEGLLDENEVAASMEVDVQEKLEQLETNMDTLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNNEDDSLSDGMNSPEPPAEKP", "length": 663 }, "evidence": [ { "id": "A0A4X1SYL5", "url": "https://omabrowser.org/oma/group/A0A4X1SYL5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P92960-1", "protein_name": "Potassium channel KAT3", "gene_name": "KAT3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTTTTEARSPLPLLLRRGRSSTALSASTAEARSPLSILQFRRRSSKDVRNITSVSSSLLPAFGTFIEDDNPSSKPFIVLHFDRRYRLWELFLVILVGYSAWASLFELAFEKAAEGALLTIDLVVDFFFAVDIILTFFVSYLDNTTYLNVTDHKLIAKRYLKSVAFVMDVASTLPIQFIYKTITGDVGRGQAFGFLNLLRLWRLRRVAELFKRLEKDAHFNYFVIRVIKLLCVTIFWIHLAGCILYWIAYHYPRPTDTWIGSQVEDFKERSVWLGYTYSMYWSIVTLTTVGYGDLHAVNSREKTFNMFYMLFNIGLTSYIIGIMTNLVVHGALRTFAMRSAINDILRYTSKNRLPDTMREQMLAHMQLKFKTAELRQEEVLQDLPKAIRSSINQHLFRSIIEEAYLFKGFPEGLLVQLVSQIQAEYFPPKMEIILQNEIPTDFYVIVSGGVDIIASKGVSEQVLAKLGPGSMAGEIGVVFNIPQPFTVRTRRLSQVIRIGHHKFKEMVQSDNDVDAKMIIANFMTYLKGLNDELKKEIPFLRDLLDDADAQVQETVQSEETPQSNDEEIVTVSRHENGQIEERRREGVPKRVIIHGQAPPNQDNKNNGDSNGRLIILPDSIQLLFDLAEKKLGKRGSTIAMADGAHVEQIDALRENDHLYIF", "length": 662 }, "evidence": [ { "id": "A0A4X1SYL5", "url": "https://omabrowser.org/oma/group/A0A4X1SYL5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q00195-1", "protein_name": "Cyclic nucleotide-gated channel alpha-2", "gene_name": "Cnga2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMTEKSNGVKSSPANNHNHHPPPSIKANGKDDHRAGSRPQSVAADDDTSPELQRLAEMDTPRRGRGGFQRIVRLVGVIRDWANKNFREEEPRPDSFLERFRGPELQTVTTHQGDDKGGKDGEGKGTKKKFELFVLDPAGDWYYRWLFVIAMPVLYNWCLLVARACFSDLQRNYFVVWLVLDYFSDTVYIADLIIRLRTGFLEQGLLVKDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHSPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYVISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKDMEAKVIKWFDYLWTNKKTVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVAASMEVDVQEKLEQLETNMDTLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNHEDDYLSDGINTPEPTAAE", "length": 664 }, "evidence": [ { "id": "A0A4X1SYL5", "url": "https://omabrowser.org/oma/group/A0A4X1SYL5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q16280-1", "protein_name": "Cyclic nucleotide-gated channel alpha-2", "gene_name": "CNGA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEKTNGVKSSPANNHNHHAPPAIKANGKDDHRTSSRPHSAADDDTSSELQRLADVDAPQQGRSGFRRIVRLVGIIREWANKNFREEEPRPDSFLERFRGPELQTVTTQEGDGKGDKDGEDKGTKKKFELFVLDPAGDWYYCWLFVIAMPVLYNWCLLVARACFSDLQKGYYLVWLVLDYVSDVVYIADLFIRLRTGFLEQGLLVKDTKKLRDNYIHTLQFKLDVASIIPTDLIYFAVDIHSPEVRFNRLLHFARMFEFFDRTETRTNYPNIFRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKGMEAKVIRWFDYLWTNKKTVDEREILKNLPAKLRAEIAINVHLSTLKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVATSMEVDVQEKLGQLETNMETLYTRFGRLLAEYTGAQQKLKQRITVLETKMKQNNEDDYLSDGMNSPELAAADEP", "length": 664 }, "evidence": [ { "id": "A0A4X1SYL5", "url": "https://omabrowser.org/oma/group/A0A4X1SYL5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62398-1", "protein_name": "Cyclic nucleotide-gated channel alpha-2", "gene_name": "Cnga2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMTEKSNGVKSSPANNHNHHPPPSIKANGKDDHRAGSRPQSVAADDDTSSELQRLAEMDTPRRGRGGFRRIVRLVGIIRDWANKNFREEEPRPDSFLERFRGPELQTVTTHQGDGKGDKDGEGKGTKKKFELFVLDPAGDWYYRWLFVIAMPVLYNWCLLVARACFSDLQRNYFVVWLVLDYFSDTVYIADLIIRLRTGFLEQGLLVKDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHSPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKDMEAKVIKWFDYLWTNKKTVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVAASMEVDVQEKLEQLETNMETLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNHEDDYLSDGINTPEPAVAE", "length": 664 }, "evidence": [ { "id": "A0A4X1SYL5", "url": "https://omabrowser.org/oma/group/A0A4X1SYL5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "pmid": "" }, { "name": "intracellularly cGMP-activated cation channel activity", "id": "GO:0005223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005223", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "pmid": "" }, { "name": "intracellularly cAMP-activated cation channel activity", "id": "GO:0005222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005222", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "pmid": "" }, { "name": "cAMP binding", "id": "GO:0030552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030552", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "pmid": "" }, { "name": "cGMP binding", "id": "GO:0030553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030553", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "pmid": "" }, { "name": "intracellular cyclic nucleotide activated cation channel complex", "id": "GO:0017071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017071", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "pmid": "" }, { "name": "non-motile cilium membrane", "id": "GO:0098804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098804", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "monoatomic cation transmembrane transport", "id": "GO:0098655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098655", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "pmid": "" }, { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SYL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "28747", "name": "", "equation": "NH4(+)(in) = NH4(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "28747", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/28747" } ] }, { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] }, { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] }, { "id": "78547", "name": "", "equation": "Rb(+)(in) = Rb(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78547", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78547" } ] }, { "id": "78551", "name": "", "equation": "Li(+)(in) = Li(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78551", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78551" } ] }, { "id": "78555", "name": "", "equation": "Cs(+)(in) = Cs(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78555", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78555" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SYL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYL5" }, { "id": "PS50042", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50042" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclic nucleotide-binding", "eco_id": "ECO_0000259", "start_pos": 453, "end_pos": 567, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 310, "end_pos": 312 }, { "start_pos": 378, "end_pos": 380 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SZM8-1", "uniprot_ac": "A0A4X1SZM8", "uniprot_id": "A0A4X1SZM8_PIG", "mass": { "chemical_mass": 10784.0, "monoisotopic_mass": 10784.0 }, "refseq": { "ac": "XP_020952736", "name": "dynein light chain roadblock-type 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020952736" }, "gene_names": [ { "name": "DYNLRB2", "type": "recommended", "evidence": [ { "id": "A0A4X1SZM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8" } ] }, { "name": "DYNLRB2", "type": "synonym", "evidence": [ { "id": "XP_020952736", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020952736" } ] } ], "protein_names": [ { "name": "Dynein light chain roadblock", "type": "recommended", "evidence": [ { "id": "A0A4X1SZM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8/entry#names_and_taxonomy" } ] }, { "name": "dynein light chain roadblock-type 2", "type": "synonym", "evidence": [ { "id": "XP_020952736", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020952736" } ] } ], "function": [ { "annotation": "Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZM8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8#function" }, { "database": "UniProtKB", "id": "PIRNR009998", "url": "https://www.uniprot.org/uniprotkb/PIRNR009998#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZM8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DYNLRB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8", "locus": { "chromosome": "6", "start_pos": 7649699, "end_pos": 7661308, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031421", "url": "https://www.ensembl.org/id/ENSSSCG00000031421" } ] } } ], "crossref": [ { "id": "A0A4X1SZM8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SZM8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000031421", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031421", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "102165562", "url": "https://www.ncbi.nlm.nih.gov/gene/102165562", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:102165562", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102165562", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NEIMCAP", "url": "https://omabrowser.org/oma/group/NEIMCAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1SZM8", "url": "https://www.orthodb.org/?gene=A0A4X1SZM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10779", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10779", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03259", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03259", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020952736", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020952736", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SZM8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SZM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHV9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHQLTVKAKGTVRDIDPQNDLTFLRIRSKKHEIMVAPDKEYLLIVIQNPCE", "length": 96, "header": "tr|A0A4X1SZM8-1|A0A4X1SZM8_PIG Isoform 1 of Dynein light chain roadblock OS=Sus scrofa OX=9823 GN=DYNLRB2 PE=3 SV=1 CANONICAL=A0A4X1SZM8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SZM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8/entry#A0A4X1SZM8-1", "sequence": { "sequence": "MAEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHQLTVKAKGTVRDIDPQNDLTFLRIRSKKHEIMVAPDKEYLLIVIQNPCE", "length": 96, "header": "tr|A0A4X1SZM8-1|A0A4X1SZM8_PIG Isoform 1 of Dynein light chain roadblock OS=Sus scrofa OX=9823 GN=DYNLRB2 PE=3 SV=1 CANONICAL=A0A4X1SZM8-1" }, "locus": { "chromosome": "6", "start_pos": 7661246, "end_pos": 7650703, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055825.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055825.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041321.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041321.1" } ] } }, { "isoform_ac": "A0A5G2QHV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8/entry#A0A5G2QHV9-1", "sequence": { "sequence": "MAEVEETLKRIQSHKGVIGTMVVNAEDKEYLLIVIQNPCE", "length": 40, "header": "tr|A0A5G2QHV9-1|A0A4X1SZM8_PIG Computationally mapped isoform of Dynein light chain roadblock OS=Sus scrofa OX=9823 GN=DYNLRB2 PE=3 SV=1 CANONICAL=A0A4X1SZM8-1" }, "locus": { "chromosome": "6", "start_pos": 7661246, "end_pos": 7650703, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097283.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097283.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077401.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077401.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QHV9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHV9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102165562", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102165562", "resource": "KEGG Pathway" }, { "id": "R-SSC-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620924", "resource": "Reactome", "description": "Intraflagellar transport" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A0A0-1", "protein_name": "Dynein light chain roadblock", "gene_name": "Dynlrb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHQLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPEPM", "length": 85 }, "evidence": [ { "id": "A0A4X1SZM8", "url": "https://omabrowser.org/oma/group/A0A4X1SZM8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32P85-1", "protein_name": "Dynein light chain roadblock-type 2", "gene_name": "DYNLRB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHQLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPDKEYLLIVIQNPCE", "length": 96 }, "evidence": [ { "id": "A0A4X1SZM8", "url": "https://omabrowser.org/oma/group/A0A4X1SZM8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8TF09-1", "protein_name": "Dynein light chain roadblock-type 2", "gene_name": "DYNLRB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHHLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPDKEYLLIVIQNPCE", "length": 96 }, "evidence": [ { "id": "A0A4X1SZM8", "url": "https://omabrowser.org/oma/group/A0A4X1SZM8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAJ5-1", "protein_name": "Dynein light chain roadblock-type 2", "gene_name": "Dynlrb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHQLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPDKEYLLIVIQNPCE", "length": 96 }, "evidence": [ { "id": "A0A4X1SZM8", "url": "https://omabrowser.org/oma/group/A0A4X1SZM8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZM8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZM8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZM8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZM8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZM8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZM8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SZM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZM8" }, { "id": "SM00960", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00960" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Roadblock/LAMTOR2", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 92, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1SZW6-1", "uniprot_ac": "A0A4X1SZW6", "uniprot_id": "A0A4X1SZW6_PIG", "mass": { "chemical_mass": 114957.0, "monoisotopic_mass": 114957.0 }, "refseq": { "ac": "XP_003122958", "name": "anoctamin-3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122958" }, "gene_names": [ { "name": "ANO3", "type": "recommended", "evidence": [ { "id": "A0A4X1SZW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6" } ] }, { "name": "ANO3", "type": "synonym", "evidence": [ { "id": "XP_003122958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122958" } ] } ], "protein_names": [ { "name": "Anoctamin", "type": "recommended", "evidence": [ { "id": "A0A4X1SZW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6/entry#names_and_taxonomy" } ] }, { "name": "anoctamin-3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_003122958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122958" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZW6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ANO3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6", "locus": { "chromosome": "2", "start_pos": 33618005, "end_pos": 33905069, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013339", "url": "https://www.ensembl.org/id/ENSSSCG00000013339" } ] } } ], "crossref": [ { "id": "A0A4X1SZW6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1SZW6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100519534", "url": "https://www.ncbi.nlm.nih.gov/gene/100519534", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519534", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519534", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SZW6", "url": "https://www.orthodb.org/?gene=A0A4X1SZW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12308:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12308:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04547", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04547", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003122958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122958", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SZW6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SZW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNMVHHSGSIQSFKQQKGMNISKSEIAKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQSIESESQAPTSVTSISADKAEQVNPEERKESVLKCSFADLSDFCLALGKDKDYMDESEHANYDRSRLIKDFVPKNNSESKTRLPKNDMNYIASSGLLFKDGKKRIDYILVYRKSNIQYDKRNTFEKNLRAEGLMLEKEPAVANPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDRRSKSMGRVQKYFRRIKKWMSQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLQHTKYENGISKVGICKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGIFTMNASQVSQEICKATEVFMCPLCDKNCSLQRLNESCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSTLTYTWDLIEWEEEEETLRPQFEAKYYKMERVNPISGKPEPHQPSSDKVTRLLVSISGIFFMISLVITAVFAVVVYRLVVMEQFASFKWNFIKQHWQFATSAAAVCINFVIIMALNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFNRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIQDASIPQWENDWNLQPMNIHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWYGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHFEYRESCLTGYVNNSLSFFDLSELGVGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKNLYDRIRREKYLVQEMMYEAELEHLQQQRRKSGHPVHHEWP", "length": 982, "header": "tr|A0A4X1SZW6-1|A0A4X1SZW6_PIG Isoform 1 of Anoctamin OS=Sus scrofa OX=9823 GN=ANO3 PE=3 SV=1 CANONICAL=A0A4X1SZW6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SZW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6/entry#A0A4X1SZW6-1", "sequence": { "sequence": "MNMVHHSGSIQSFKQQKGMNISKSEIAKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQSIESESQAPTSVTSISADKAEQVNPEERKESVLKCSFADLSDFCLALGKDKDYMDESEHANYDRSRLIKDFVPKNNSESKTRLPKNDMNYIASSGLLFKDGKKRIDYILVYRKSNIQYDKRNTFEKNLRAEGLMLEKEPAVANPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDRRSKSMGRVQKYFRRIKKWMSQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLQHTKYENGISKVGICKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGIFTMNASQVSQEICKATEVFMCPLCDKNCSLQRLNESCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSTLTYTWDLIEWEEEEETLRPQFEAKYYKMERVNPISGKPEPHQPSSDKVTRLLVSISGIFFMISLVITAVFAVVVYRLVVMEQFASFKWNFIKQHWQFATSAAAVCINFVIIMALNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFNRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIQDASIPQWENDWNLQPMNIHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWYGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHFEYRESCLTGYVNNSLSFFDLSELGVGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKNLYDRIRREKYLVQEMMYEAELEHLQQQRRKSGHPVHHEWP", "length": 982, "header": "tr|A0A4X1SZW6-1|A0A4X1SZW6_PIG Isoform 1 of Anoctamin OS=Sus scrofa OX=9823 GN=ANO3 PE=3 SV=1 CANONICAL=A0A4X1SZW6-1" }, "locus": { "chromosome": "2", "start_pos": 33904915, "end_pos": 33621621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049311.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049311.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038425.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038425.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZW6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519534", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519534", "resource": "KEGG Pathway" }, { "id": "R-SSC-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZW6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZW6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZW6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6" } ], "pmid": "" }, { "name": "phospholipid scramblase activity", "id": "GO:0017128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017128", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZW6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1SZW6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 867, "end_pos": 869, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1SZW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6" }, { "id": "PF16178", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anoctamin dimerisation", "eco_id": "ECO_0000259", "start_pos": 158, "end_pos": 382, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1SZW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SZW6" }, { "id": "PF04547", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04547" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anoctamin transmembrane", "eco_id": "ECO_0000259", "start_pos": 385, "end_pos": 950, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 20, "end_pos": 22 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 651, "end_pos": 653 }, { "start_pos": 867, "end_pos": 869 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T012-1", "uniprot_ac": "A0A4X1T012", "uniprot_id": "A0A4X1T012_PIG", "mass": { "chemical_mass": 40032.0, "monoisotopic_mass": 40032.0 }, "refseq": { "ac": "XP_003482347", "name": "psychosine receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482347" }, "gene_names": [ { "name": "GPR65", "type": "recommended", "evidence": [ { "id": "A0A4X1T012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012" } ] }, { "name": "GPR65", "type": "synonym", "evidence": [ { "id": "XP_003482347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482347" } ] } ], "protein_names": [ { "name": "G-protein coupled receptor 65", "type": "recommended", "evidence": [ { "id": "A0A4X1T012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012/entry#names_and_taxonomy" } ] }, { "name": "T-cell death-associated gene 8 protein", "type": "synonym", "evidence": [ { "id": "A0A4X1T012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012/entry#names_and_taxonomy" } ] }, { "name": "psychosine receptor", "type": "synonym", "evidence": [ { "id": "XP_003482347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482347" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T012", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GPR65", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012", "locus": { "chromosome": "7", "start_pos": 109989280, "end_pos": 109985307, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021146", "url": "https://www.ensembl.org/id/ENSSSCG00000021146" } ] } } ], "crossref": [ { "id": "A0A4X1T012", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T012", "database": "AlphaFoldDB", "categories": [] }, { "id": "100155711", "url": "https://www.ncbi.nlm.nih.gov/gene/100155711", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155711", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155711", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICNQKVY", "url": "https://omabrowser.org/oma/group/ICNQKVY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T012", "url": "https://www.orthodb.org/?gene=A0A4X1T012", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24234:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24234:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003482347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482347", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T012", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T012-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSTCIEEQHDLDHYLFPVVYIFVVIVSVPANIGSLCVSFLQAKKENELGIYLFSLSLSDLLYALTLPLWIDYTWNQDNWTFSPALCKGSAFFMYMNFYSSTAFLTCIAIDRYLAVVYPLRFSFLRSRRFAFMVSLFIWVLESFFNAIILWEDETAVEYCDTKKSNFTLCYDKYPLEKWQIKFNFFRTCVGYLIPLVVIMVCNRKVYQAVKQNQATENSEKKRIIKLLVSITLTFILCFTPFHVMLLIRSILERDVNLDEHIFDHNKSGKQTYKIYRITVALTSLNCVADPMLYCFVTETGRSDMWNILNFFTGKFNKSERQRKSMLSMSTRDTLELDILD", "length": 341, "header": "tr|A0A4X1T012-1|A0A4X1T012_PIG Isoform 1 of G-protein coupled receptor 65 OS=Sus scrofa OX=9823 GN=GPR65 PE=3 SV=1 CANONICAL=A0A4X1T012-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T012-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012/entry#A0A4X1T012-1", "sequence": { "sequence": "MNSTCIEEQHDLDHYLFPVVYIFVVIVSVPANIGSLCVSFLQAKKENELGIYLFSLSLSDLLYALTLPLWIDYTWNQDNWTFSPALCKGSAFFMYMNFYSSTAFLTCIAIDRYLAVVYPLRFSFLRSRRFAFMVSLFIWVLESFFNAIILWEDETAVEYCDTKKSNFTLCYDKYPLEKWQIKFNFFRTCVGYLIPLVVIMVCNRKVYQAVKQNQATENSEKKRIIKLLVSITLTFILCFTPFHVMLLIRSILERDVNLDEHIFDHNKSGKQTYKIYRITVALTSLNCVADPMLYCFVTETGRSDMWNILNFFTGKFNKSERQRKSMLSMSTRDTLELDILD", "length": 341, "header": "tr|A0A4X1T012-1|A0A4X1T012_PIG Isoform 1 of G-protein coupled receptor 65 OS=Sus scrofa OX=9823 GN=GPR65 PE=3 SV=1 CANONICAL=A0A4X1T012-1" }, "locus": { "chromosome": "7", "start_pos": 109989083, "end_pos": 109988061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022745.4", "url": "https://www.ensembl.org/id/ENSSSCT00000022745.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079953.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079953.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T012", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155711", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155711", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0YIR8-1", "protein_name": "G-protein coupled receptor 65", "gene_name": "Gpr65", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTMNSTCVEEQHDLDHYLFPVVYIFVFIVSVPANIGSLCVSFLQAKKENELGVYLFSLSLSDLLYALTLPLWINYTWNKDNWTLSPTLCKGSVFFTYLNFYSSTAFLTCIALDRYLAVVYPLRFSFLRTRRFAFITSLSIWILESVFNSILLWEDETSVEYCDAEKSNFTLCYDKYPLEKWQINLNLFRTFLGYAIPLVTIMICNHKVYRAVKHNQATENNERRRIIKLLASITLTFILCFTPFHVMVLIRCILERNVNFNNKTGKQTFTVYRITVALTSLNCVADPILYCFVTETGRSDMWNILKVCARKRNRSRGQKRDILSVSTRDTIELEIIE", "length": 337 }, "evidence": [ { "id": "A0A4X1T012", "url": "https://omabrowser.org/oma/group/A0A4X1T012/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NJ83-1", "protein_name": "G-protein coupled receptor 65", "gene_name": "GPR65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNNTAKCHDDHALDKYLFPFVYSTVMVISIPINCISLYVSCIQVRKKNELAVYLFSLSMADLLYSVILPLWIDYAWNGDNWTLSARLCQFSAFLMYMNFYTSTALLACISLDRYLALVHPLKFQHLRTRRISLIVSIIVWLLEGTVNSVILMNKDVFHDPCNSTDHTLCYDKYPLELWQARLNLFRICSGYLLPLIIILFCYHKIYQAVRCNQATVDEEKKKIRKLILNITITFIVCFTPYHVVLLIRSIKEPQTSDLQLLQSMYKIYRITQAFTSLNCIADPILYCFVSESAQTDILNLLRCCLCLQKPEGNQPEEYALCNSATKSNALVTYRSSCETQTQ", "length": 342 }, "evidence": [ { "id": "A0A4X1T012", "url": "https://omabrowser.org/oma/group/A0A4X1T012/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q61038-1", "protein_name": "G protein-coupled receptor 65", "gene_name": "Gpr65", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMNSMCIEEQHHLEHYLFPVVYIIVFIVSVPANIGSLCVSFLQAKKENELGIYLFSLSLSDLLYALTLPLWINYTWNKDNWTFSPTLCKGSVFFTYMNFYSSTAFLTCIALDRYLAVVYPLKFSFLRTRRFAFITSLSIWILESFFNSMLLWKDETSVEYCDSDKSNFTLCYDKYPLEKWQINLNLFRTCMGYAIPLITIMICNHKVYRAVRHNQATENSEKRRIIKLLASITLTFVLCFTPFHVMVLIRCVLERDMNVNDKSGWQTFTVYRVTVALTSLNCVADPILYCFVTETGRADMWNILKLCTRKHNRHQGQKRDILSVSTRDAVELEIID", "length": 337 }, "evidence": [ { "id": "A0A4X1T012", "url": "https://omabrowser.org/oma/group/A0A4X1T012/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYL9-1", "protein_name": "G protein-coupled receptor 65", "gene_name": "GPR65", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSTCIEEQHDLDHYLFPIVYIFVIIVSIPANIGSLCVSFLQAKKESELGIYLFSLSLSDLLYALTLPLWIDYTWNKDNWTFSPALCKGSAFLMYMNFYSSTAFLTCIAVDRYLAVVYPLKFFFLRTRRFALMVSLSIWILETIFNAVMLWEDETVVEYCDAEKSNFTLCYDKYPLEKWQINLNLFRTCTGYAIPLVTILICNRKVYQAVRHNKATENKEKKRIIKLLVSITVTFVLCFTPFHVMLLIRCILEHAVNFEDHSNSGKRTYTMYRITVALTSLNCVADPILYCFVTETGRYDMWNILKFCTGRCNTSQRQRKRILSVSTKDTMELEVLE", "length": 337 }, "evidence": [ { "id": "A0A4X1T012", "url": "https://omabrowser.org/oma/group/A0A4X1T012/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T012", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T012", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T012", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T012", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T012", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T012", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012" } ], "pmid": "" }, { "name": "cellular response to acidic pH", "id": "GO:0071468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071468", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T012", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T012" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 294, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 }, { "start_pos": 266, "end_pos": 268 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T0K4-1", "uniprot_ac": "A0A4X1T0K4", "uniprot_id": "A0A4X1T0K4_PIG", "mass": { "chemical_mass": 131845.0, "monoisotopic_mass": 131845.0 }, "refseq": { "ac": "XP_020931617", "name": "unconventional myosin-Ib isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931617" }, "gene_names": [ { "name": "MYO1B", "type": "recommended", "evidence": [ { "id": "A0A4X1T0K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ] }, { "name": "MYO1B", "type": "synonym", "evidence": [ { "id": "XP_020931617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931617" } ] } ], "protein_names": [ { "name": "Unconventional myosin-Ib", "type": "recommended", "evidence": [ { "id": "A0A4X1T0K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4/entry#names_and_taxonomy" } ] }, { "name": "Myosin I alpha", "type": "synonym", "evidence": [ { "id": "A0A4X1T0K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4/entry#names_and_taxonomy" } ] }, { "name": "unconventional myosin-Ib isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020931617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931617" } ] } ], "function": [ { "annotation": "Motor protein that may participate in process critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1P2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1P2#function" }, { "database": "UniProtKB", "id": "ARBA00058091", "url": "https://www.uniprot.org/uniprotkb/ARBA00058091#function" }, { "database": "UniProtKB", "id": "A0A4X1T0M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0M0#function" }, { "database": "UniProtKB", "id": "A0A4X1T1M6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1M6#function" }, { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4#function" }, { "database": "UniProtKB", "id": "A0A5G2QDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDQ8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MYO1B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4", "locus": { "chromosome": "15", "start_pos": 96066990, "end_pos": 95874412, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016061", "url": "https://www.ensembl.org/id/ENSSSCG00000016061" } ] } } ], "crossref": [ { "id": "A0A4X1T0K4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T0K4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016061", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016061", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01378", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01378", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100517198", "url": "https://www.ncbi.nlm.nih.gov/gene/100517198", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NARKMYS", "url": "https://omabrowser.org/oma/group/NARKMYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13140:SF277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140:SF277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020931617", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931617", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T0K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T0M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T0M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1M6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1M6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1P2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QDQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0QBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8D0QBM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0QBM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0QBM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKMEVKTSLLDNMIGVGDMVLLEPLNEETVINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGGSEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREGIEWTHIEYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEGLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARAGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMRKSQIVIAAWYRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCQEAATTIAAYWHGTQARRELSRLKAEARNKHAIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIMQKYFLEMKNKVPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGPYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTNRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAIHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1136, "header": "tr|A0A4X1T0K4-1|A0A4X1T0K4_PIG Isoform 1 of Unconventional myosin-Ib OS=Sus scrofa OX=9823 GN=MYO1B PE=1 SV=1 CANONICAL=A0A4X1T0K4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T0K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4/entry#A0A4X1T0K4-1", "sequence": { "sequence": "MAKMEVKTSLLDNMIGVGDMVLLEPLNEETVINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGGSEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREGIEWTHIEYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEGLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARAGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMRKSQIVIAAWYRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCQEAATTIAAYWHGTQARRELSRLKAEARNKHAIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIMQKYFLEMKNKVPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGPYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTNRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAIHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1136, "header": "tr|A0A4X1T0K4-1|A0A4X1T0K4_PIG Isoform 1 of Unconventional myosin-Ib OS=Sus scrofa OX=9823 GN=MYO1B PE=1 SV=1 CANONICAL=A0A4X1T0K4-1" }, "locus": { "chromosome": "15", "start_pos": 96064978, "end_pos": 95908216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054157.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054157.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055278.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055278.1" } ] } }, { "isoform_ac": "A0A4X1T0M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4/entry#A0A4X1T0M0-1", "sequence": { "sequence": "MAKMEVKTSLLDNMIGVGDMVLLEPLNEETVINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGGSEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREGIEWTHIEYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEGLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARAGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMRKSQIVIAAWYRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCQEAATTIAAYWHGTQARRELSRLKAEARNKHAIAVIWAYWLGSKVRREYRKFFRANAGKKIYEFTLQRIMQKYFLEMKNKVPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGPYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTNRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAIHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1107, "header": "tr|A0A4X1T0M0-1|A0A4X1T0M0_PIG Computationally mapped isoform of Unconventional myosin-Ib OS=Sus scrofa OX=9823 GN=MYO1B PE=1 SV=1 CANONICAL=A0A4X1T0K4-1" }, "locus": { "chromosome": "15", "start_pos": 96064978, "end_pos": 95908216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055105.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055105.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043777.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043777.1" } ] } }, { "isoform_ac": "A0A4X1T1M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4/entry#A0A4X1T1M6-1", "sequence": { "sequence": "MAKMEVKTSLLDNMIGVGDMVLLEPLNEETVINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGGSEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREGIEWTHIEYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEGLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARAGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMRKSQIVIAAWYRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCQEAATTIAAYWHGTQARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIMQKYFLEMKNKVPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGPYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTNRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAIHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1107, "header": "tr|A0A4X1T1M6-1|A0A4X1T1M6_PIG Computationally mapped isoform of Unconventional myosin-Ib OS=Sus scrofa OX=9823 GN=MYO1B PE=1 SV=1 CANONICAL=A0A4X1T0K4-1" }, "locus": { "chromosome": "15", "start_pos": 96064978, "end_pos": 95908216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053923.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053923.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046305.1", "url": "https://www.ensembl.org/id/ENSSSCP00000046305.1" } ] } }, { "isoform_ac": "A0A4X1T1P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4/entry#A0A4X1T1P2-1", "sequence": { "sequence": "MAKMEVKTSLLDNMIGVGDMVLLEPLNEETVINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGGSEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREGIEWTHIEYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEGLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARAGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMRKSQIVIAAWYRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCQEAATTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRIMQKYFLEMKNKVPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGPYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTNRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAIHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1078, "header": "tr|A0A4X1T1P2-1|A0A4X1T1P2_PIG Computationally mapped isoform of Unconventional myosin-Ib OS=Sus scrofa OX=9823 GN=MYO1B PE=1 SV=1 CANONICAL=A0A4X1T0K4-1" }, "locus": { "chromosome": "15", "start_pos": 96064978, "end_pos": 95908216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064666.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064666.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059511.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059511.1" } ] } }, { "isoform_ac": "A0A5G2QDQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4/entry#A0A5G2QDQ8-1", "sequence": { "sequence": "MAKMEVKTSLLDNMIGVGDMVLLEPLNEETVINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGGSEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKRGIVMGALMDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREGIEWTHIEYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEGLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARAGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMRKSQIVIAAWYRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCQEAATTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRIMQKYFLEMKNKVPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGPYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTNRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAIHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1065, "header": "tr|A0A5G2QDQ8-1|A0A4X1T0K4_PIG Computationally mapped isoform of Unconventional myosin-Ib OS=Sus scrofa OX=9823 GN=MYO1B PE=1 SV=1 CANONICAL=A0A4X1T0K4-1" }, "locus": { "chromosome": "15", "start_pos": 96064978, "end_pos": 95908216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087528.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087528.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062278.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062278.1" } ] } }, { "isoform_ac": "A0A8D0QBM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4/entry#A0A8D0QBM6-1", "sequence": { "sequence": "MIGVGDMVLLEPLNEETVINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGGSEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREGIEWTHIEYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEGLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARAGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMRKSQIVIAAWYRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCQEAATTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRIMQKYFLEMKNKVPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGPYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTNRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAIHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1036, "header": "tr|A0A8D0QBM6-1|A0A4X1T0K4_PIG Computationally mapped isoform of Unconventional myosin-Ib OS=Sus scrofa OX=9823 GN=MYO1B PE=1 SV=1 CANONICAL=A0A4X1T0K4-1" }, "locus": { "chromosome": "15", "start_pos": 96064978, "end_pos": 95908255, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017486.3", "url": "https://www.ensembl.org/id/ENSSSCT00000017486.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017014.3", "url": "https://www.ensembl.org/id/ENSSSCP00000017014.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDQ8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1RIU5-1", "protein_name": "Unconventional myosin-Ib", "gene_name": "myo1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEVKTSLLDNMIGVGDMVLLEPLSEESFIENLKKRFDHNEIYTYIGSVVISMNPYKSLSIYSAEKVEEYRNRNFYELSPHIYALADEAYRSLRHQDKDQCILITGESGAGKTEASKFVMSYVAAVCGKGQEVNKVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHIFYQLLSGASDDMLKKLKLDRDFSKYNYLSLDSATVNGLDDAASFRTVRNAMQIVGFMEDEVQSILELIAAVLKLGNIEFKPESRVNGFDESRVKDKNDLKEMCELLGIEQSVLERAFSFRTVEAKMEKVSTTLNVAQAYYARDALAKNLYSRLFTWLVNRINESIKAQTKTRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLREEQEEYIREGIEWTNIEYFNNAIICDLIENNKNGILAMLDEECLRPGTVTDETFLDKLNTVCAEHQHFESRLSKNSKFLTDHSLPHNCFRIQHYAGKVLYRVEGFVDKNNDLLYRDLSQAMYKANHNLIKLLFPEGNPAKVNLKRPPTAGFQFRASVGTLMKNLLTKNPNYIRCIKPNDKKAAHIFTDSLVCHQVRYLGLMENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPAREGVEVLLSDLQVPAEEFAYGRSKIFIRNPRTLFFLEEKRRQCLEDLAALIQKIYRGWKCRTHFLLLKKSQVVVAAWYRRFAQQKKYQKIRCSALVVQSFIRGWKARKLLRELKHKKRCEEAVTTISAYWHGTQARWELRRLKKEAWNKHAVSVIWAAWLGTKARRELQKLKHEACSKQAVSVIWACWQGTKARRELKRLKEEARRKHAIAVIWAYWLGLKVRREYRKFFRANAGKKIYDFTIQRIIQKYYLGLKKTMPSMSPIDKSWSTCPYGFLDGTHQELRRIFHLWRCKKYRSQFTEEKKATYEEKLAASELFKDKKALYPSSVSQPFKGDYVEITKNPKYQKLNSLVEDKVLLADVVSKINRANGKGTPRIFLLTKKCLVLADQKTGQVKASVPLPDLSSVFVSTQNDGFFALKLREGATSAAKGDYLLSSDRLIEIITKLYCTGAASAERNQIKIDISDEFLVQFKQDKVCVKFIQGTPKNSNSVSCKRKNNRLLEVSVPSP", "length": 1165 }, "evidence": [ { "id": "A0A4X1T0K4", "url": "https://omabrowser.org/oma/group/A0A4X1T0K4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O43795-1", "protein_name": "Unconventional myosin-Ib", "gene_name": "MYO1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKMEVKTSLLDNMIGVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1136 }, "evidence": [ { "id": "A0A4X1T0K4", "url": "https://omabrowser.org/oma/group/A0A4X1T0K4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P46735-1", "protein_name": "Unconventional myosin-Ib", "gene_name": "Myo1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKMEVKSSLLDNMIGVGDMVLLEPLNEETFIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLYKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFLDHEAEAVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTSIDQVVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTTLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHSLIKSLFPEGNPAKVNLKRPPTAGSQFKASVATLMRNLQTKNPNYIRCIKPNDKKAAHIFNESLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEHSFGRSKIFIRNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKRSQVVIAAWYRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCKEAATTIAAYWHGTQARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYLLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1107 }, "evidence": [ { "id": "A0A4X1T0K4", "url": "https://omabrowser.org/oma/group/A0A4X1T0K4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q05096-1", "protein_name": "Unconventional myosin-Ib", "gene_name": "Myo1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKKEVKSSLLDNMIGVGDTVLLEPLNEETFIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSTPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLHKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFSDPEAESVLEVVAAVLKLGNIEFKPESRMNGLDESKIKDKNELKEICELTSIDQVVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTTLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHALIKSLFPEGNPAKVNLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFSESLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKRSQVVIAAWYRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCKEAATTIAAYWHGTQARKERRRLKDEARNKHAIAVIWAFWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYLLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1136 }, "evidence": [ { "id": "A0A4X1T0K4", "url": "https://omabrowser.org/oma/group/A0A4X1T0K4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" }, { "name": "post-Golgi vesicle-mediated transport", "id": "GO:0006892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006892", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0K4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1117, "end_pos": 1119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T0K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" }, { "id": "PS51456", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51456" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin motor", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 701, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T0K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0K4" }, { "id": "PS51757", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51757" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TH1", "eco_id": "ECO_0000259", "start_pos": 952, "end_pos": 1136, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1117, "end_pos": 1119 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 501, "end_pos": 503 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T0R0-1", "uniprot_ac": "A0A4X1T0R0", "uniprot_id": "A0A4X1T0R0_PIG", "mass": { "chemical_mass": 25702.0, "monoisotopic_mass": 25702.0 }, "refseq": {}, "gene_names": [ { "name": "CD79B", "type": "recommended", "evidence": [ { "id": "A0A4X1T0R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" } ] } ], "protein_names": [ { "name": "B-cell antigen receptor complex-associated protein beta chain", "type": "recommended", "evidence": [ { "id": "A0A4X1T0R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0/entry#names_and_taxonomy" } ] }, { "name": "B-cell-specific glycoprotein B29", "type": "synonym", "evidence": [ { "id": "A0A4X1T0R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0/entry#names_and_taxonomy" } ] }, { "name": "Ig-beta", "type": "synonym", "evidence": [ { "id": "A0A4X1T0R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0/entry#names_and_taxonomy" } ] }, { "name": "Immunoglobulin-associated B29 protein", "type": "synonym", "evidence": [ { "id": "A0A4X1T0R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "K7GK92", "url": "https://www.uniprot.org/uniprotkb/K7GK92#function" }, { "database": "UniProtKB", "id": "ARBA00056166", "url": "https://www.uniprot.org/uniprotkb/ARBA00056166#function" }, { "database": "UniProtKB", "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CD79B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0", "locus": { "chromosome": "12", "start_pos": 15056438, "end_pos": 15053007, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017283", "url": "https://www.ensembl.org/id/ENSSSCG00000017283" } ] } } ], "crossref": [ { "id": "A0A4X1T0R0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T0R0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017283", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017283", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PVHFICY", "url": "https://omabrowser.org/oma/group/PVHFICY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR14334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14334:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14334:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5690714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T0R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GK92", "url": "https://www.uniprot.org/uniprotkb/K7GK92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GK92-1", "url": "https://www.uniprot.org/uniprotkb/K7GK92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPALSPGLSNWLVLLLLLLSGETVLEAETKELRDPKGGACSRIWQHPRFVARKRGSMVEIRCYVEDPGIVSWLRKQEADLEPKIFPPEEGRIIQNQTTSEATLIIQGVQFQDNGVYYCKQECSKEPLRTEQGCGTELRVMGFSTLAQLKRRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKPGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQE", "length": 228, "header": "tr|A0A4X1T0R0-1|A0A4X1T0R0_PIG Isoform 1 of B-cell antigen receptor complex-associated protein beta chain OS=Sus scrofa OX=9823 GN=CD79B PE=4 SV=1 CANONICAL=A0A4X1T0R0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T0R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0/entry#A0A4X1T0R0-1", "sequence": { "sequence": "MAGPALSPGLSNWLVLLLLLLSGETVLEAETKELRDPKGGACSRIWQHPRFVARKRGSMVEIRCYVEDPGIVSWLRKQEADLEPKIFPPEEGRIIQNQTTSEATLIIQGVQFQDNGVYYCKQECSKEPLRTEQGCGTELRVMGFSTLAQLKRRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKPGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQE", "length": 228, "header": "tr|A0A4X1T0R0-1|A0A4X1T0R0_PIG Isoform 1 of B-cell antigen receptor complex-associated protein beta chain OS=Sus scrofa OX=9823 GN=CD79B PE=4 SV=1 CANONICAL=A0A4X1T0R0-1" }, "locus": { "chromosome": "12", "start_pos": 15055943, "end_pos": 15053072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018815.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018815.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018313.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018313.2" } ] } }, { "isoform_ac": "A0A5G2QXE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0/entry#A0A5G2QXE5-1", "sequence": { "sequence": "MAGPALSPGLSNWLVLLLLLLSGETVLEAETKELRDPKGFSTLAQLKRRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKPGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQE", "length": 124, "header": "tr|A0A5G2QXE5-1|A0A4X1T0R0_PIG Computationally mapped isoform of B-cell antigen receptor complex-associated protein beta chain OS=Sus scrofa OX=9823 GN=CD79B PE=4 SV=1 CANONICAL=A0A4X1T0R0-1" }, "locus": { "chromosome": "12", "start_pos": 15055943, "end_pos": 15053072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077685.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077685.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069546.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069546.1" } ] } }, { "isoform_ac": "K7GK92-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0/entry#K7GK92-1", "sequence": { "sequence": "MAGPALSPGLSNWLVLLLLLLSGETVLEAETKELRDPKGGACSRIWQHPRFVARKRGSMVEIRCYVEDPGIVSWLRKQEADLEPKIFPPEEGRIIQNQTTSEATLIIQGVQFQDNGVYYCKQECSKAPEDEQGCGTELRVMGFSTLAQLKRRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKPGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQE", "length": 227, "header": "tr|K7GK92-1|A0A4X1T0R0_PIG Computationally mapped isoform of B-cell antigen receptor complex-associated protein beta chain OS=Sus scrofa OX=9823 GN=CD79B PE=4 SV=3 CANONICAL=A0A4X1T0R0-1" }, "locus": { "chromosome": "12", "start_pos": 15055943, "end_pos": 15053072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035489.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035489.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028265.3", "url": "https://www.ensembl.org/id/ENSSSCP00000028265.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXE5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5690714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690714", "resource": "Reactome", "description": "CD22 mediated BCR regulation" }, { "id": "R-SSC-983695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983695", "resource": "Reactome", "description": "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4ID76-1", "protein_name": "Uncharacterized protein cd79b isoform X1", "gene_name": "cd79b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVLICMFLRSIFTALDLHLLAEAGLCSGELYSFCSLSVTDVYITFRGGFEDFNIMHHFLLGFSVMALIYLSAEGSIIVFQKPRFIGVKTGRTVIIYCVPSNPTRGPARVQWFKNKNYQSSLTNDQRITINDRNNDKNASITLKKVETEDSGTYVCKLNDTFGPGTALQVSRYSEPHAVLMRSRVKDVIIFLQAFLLVLCIVVPLVRLYKLEKKEEAEYEEPEDDHIYEGLEIEQVGGDVYEDISTFAQSSDAAWQVESPCQE", "length": 263 }, "evidence": [ { "id": "A0A4X1T0R0", "url": "https://omabrowser.org/oma/group/A0A4X1T0R0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8J8XPU7-1", "protein_name": "B-cell antigen receptor complex-associated protein beta chain", "gene_name": "Cd79b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLPSRVPGEMVPPLGLNLHGRKGPNGEEVERRKVAARADTQLHVLPQTLLGLRDRAVTMATLVLSPVPCHWLMFLLLLLSGEPVPAMTKSDQPPIFQGSPCSKIWQHPRFAAKKRSSMVKFHCHTDYSGVMTWFRQKGNQRPQELFPEDGHISQTRNGSVYTLTLQNIQYEDNGIYFCQQKCNSTEPDVTDGCGTELLVLGFSTLDQLKRRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLNIDQTATYEDIVTLRTGEVKWSVGEHPGQE", "length": 287 }, "evidence": [ { "id": "A0A4X1T0R0", "url": "https://omabrowser.org/oma/group/A0A4X1T0R0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9SAP4-1", "protein_name": "B-cell antigen receptor complex-associated protein beta chain", "gene_name": "CD79B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGSALIPGLNNWLVLGLLLLSGEKVLADKTDDLLRDPKGNTCSRIWQHPRFVAKKRGSTVEIRCHVEDDGLVSWFRKPKPDSEPKTLHAEQGRILQSHNKSEAVLTILSVQFQDNGIYFCKQECAKGTQRTEHGCGTELRVMGFSTLAQLKRRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQE", "length": 229 }, "evidence": [ { "id": "A0A4X1T0R0", "url": "https://omabrowser.org/oma/group/A0A4X1T0R0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P15530-1", "protein_name": "B-cell antigen receptor complex-associated protein beta chain", "gene_name": "Cd79b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATLVLSSMPCHWLLFLLLLFSGEPVPAMTSSDLPLNFQGSPCSQIWQHPRFAAKKRSSMVKFHCYTNHSGALTWFRKRGSQQPQELVSEEGRIVQTQNGSVYTLTIQNIQYEDNGIYFCKQKCDSANHNVTDSCGTELLVLGFSTLDQLKRRNTLKDGIILIQTLLIILFIIVPIFLLLDKDDGKAGMEEDHTYEGLNIDQTATYEDIVTLRTGEVKWSVGEHPGQE", "length": 228 }, "evidence": [ { "id": "A0A4X1T0R0", "url": "https://omabrowser.org/oma/group/A0A4X1T0R0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P40259-1", "protein_name": "B-cell antigen receptor complex-associated protein beta chain", "gene_name": "CD79B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARLALSPVPSHWMVALLLLLSAEPVPAARSEDRYRNPKGSACSRIWQSPRFIARKRGFTVKMHCYMNSASGNVSWLWKQEMDENPQQLKLEKGRMEESQNESLATLTIQGIRFEDNGIYFCQQKCNNTSEVYQGCGTELRVMGFSTLAQLKQRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQE", "length": 229 }, "evidence": [ { "id": "A0A4X1T0R0", "url": "https://omabrowser.org/oma/group/A0A4X1T0R0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8AV16-1", "protein_name": "B-cell antigen receptor complex-associated protein beta chain", "gene_name": "CD79B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGDFCRRLWVLQVNLWLMAVAAGGIPTDGNSTSNRTGSECVGMWQHPRYIAAKKNTSVHFICYTSQPHAMQWYKALGNGKEFHVLDQSSDRFSINNTNDRISFTISRISYEDNGIYVCDSKNLTEEKRQPNSCGTEIRVMSRSNIQQIQNRNTLKDTIIIIQTILLVIFISVPMLLFLEKGDRKERPEEDHTYEGLEVEQIATYEDITPFRDMKAKWTVGEHPGEE", "length": 226 }, "evidence": [ { "id": "A0A4X1T0R0", "url": "https://omabrowser.org/oma/group/A0A4X1T0R0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" } ], "pmid": "" }, { "name": "B cell receptor complex", "id": "GO:0019815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019815", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" } ], "pmid": "" }, { "name": "IgM B cell receptor complex", "id": "GO:0071755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071755", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T0R0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T0R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T0R0" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 120, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T166-1", "uniprot_ac": "A0A4X1T166", "uniprot_id": "A0A4X1T166_PIG", "mass": { "chemical_mass": 47544.0, "monoisotopic_mass": 47544.0 }, "refseq": { "ac": "NP_999334", "name": "carboxypeptidase B precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999334" }, "gene_names": [ { "name": "CPB1", "type": "recommended", "evidence": [ { "id": "A0A4X1T166", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166" } ] }, { "name": "CPB1", "type": "synonym", "evidence": [ { "id": "NP_999334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999334" } ] } ], "protein_names": [ { "name": "Carboxypeptidase B", "type": "recommended", "evidence": [ { "id": "A0A4X1T166", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166/entry#names_and_taxonomy" } ] }, { "name": "3.4.17.2", "type": "synonym", "evidence": [ { "id": "A0A4X1T166", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166/entry#names_and_taxonomy" } ] }, { "name": "carboxypeptidase B precursor", "type": "synonym", "evidence": [ { "id": "NP_999334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999334" } ] }, { "name": "carboxypeptidase B1 (tissue)", "type": "synonym", "evidence": [ { "id": "NP_999334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999334" } ] }, { "name": "carboxypeptidase B", "type": "synonym", "evidence": [ { "id": "NP_999334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999334" } ] }, { "name": "procarboxypeptidase B", "type": "synonym", "evidence": [ { "id": "NP_999334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999334" } ] } ], "function": [ { "annotation": "Its catalytically important Tyr248 residue is oriented and hydrogen-bonded to solvent water molecules, and locates the furthest away from the catalytic zinc ion as compared to previous structures.", "evidence": [ { "database": "RefSeq", "id": "NP_999334", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999334" }, { "database": "PubMed", "id": "19802820", "url": "https://glygen.org/publication/PubMed/19802820" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T166", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CPB1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166", "locus": { "chromosome": "13", "start_pos": 89088392, "end_pos": 89044310, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011694", "url": "https://www.ensembl.org/id/ENSSSCG00000011694" } ] } } ], "crossref": [ { "id": "A0A4X1T166", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T166", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03871", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03871", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "397341", "url": "https://www.ncbi.nlm.nih.gov/gene/397341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:397341", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:397341", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WPYKWEG", "url": "https://omabrowser.org/oma/group/WPYKWEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T166", "url": "https://www.orthodb.org/?gene=A0A4X1T166", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_999334", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999334", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T166", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T166-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAFLILVTVTLASAHHSGEHFEGEKVFRVNVEDENDISLLHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVEDFLEQNELQYEVLINNLRSVLEAQFDSRVRTTGHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHLY", "length": 417, "header": "tr|A0A4X1T166-1|A0A4X1T166_PIG Isoform 1 of Carboxypeptidase B OS=Sus scrofa OX=9823 GN=CPB1 PE=3 SV=1 CANONICAL=A0A4X1T166-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T166-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166/entry#A0A4X1T166-1", "sequence": { "sequence": "MLAFLILVTVTLASAHHSGEHFEGEKVFRVNVEDENDISLLHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVEDFLEQNELQYEVLINNLRSVLEAQFDSRVRTTGHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHLY", "length": 417, "header": "tr|A0A4X1T166-1|A0A4X1T166_PIG Isoform 1 of Carboxypeptidase B OS=Sus scrofa OX=9823 GN=CPB1 PE=3 SV=1 CANONICAL=A0A4X1T166-1" }, "locus": { "chromosome": "13", "start_pos": 89088205, "end_pos": 89044314, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012802.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012802.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012464.3", "url": "https://www.ensembl.org/id/ENSSSCP00000012464.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Analysis of a new crystal form of procarboxypeptidase B: further insights into the catalytic mechanism.", "journal": "Biopolymers", "date": "2010-02", "authors": "Fern\u00e1ndez Daniel, Boix Ester, Pallar\u00e8s Irantzu, Avil\u00e9s Francesc X, Vendrell Josep", "evidence": [ { "database": "RefSeq", "id": "NP_999334", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999334" } ], "reference": [ { "type": "PubMed", "id": "19802820", "url": "https://glygen.org/publication/PubMed/19802820" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T166", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:397341", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:397341", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BW20-1", "protein_name": "Carboxypeptidase B", "gene_name": "CPB1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MWAFLVLVGAAVASAHLQDQTFDGHKVFRVIPQDNEQVEIIRSLASKMKLDFWQPDSVKMVKPKRQVDFRVEADKTLEVEHLLKENKMDFNVLIDNLQTALHAQFDSKVRGTGHSYEKYNTWDTIAAWTADIAAENPTLVSRSVIGETYEGQPLYLLKLGKSGTNKKAIFMDCGFHAREWISPAFCQWFVKEAVETYGTDSTMTKLLNSLDFYVLPVVNIDGYVYSWTKDRMWRKTRSKNTGSSCIGTDLNRNFNAGWCELGASDRPCASTYCGSAPESEKESKALADFIRENLSTIKAYLTVHSYSQLLVFPYSYTYKLAKDYNELNTVASAAIQRLTSLYNTNYEYGPGAATVYPAAGGSDDWAYDQGIKYSFTFELRDTGKYGFLLPESQIKPTCEETMLAVKYIASYVLDHLY", "length": 417 }, "evidence": [ { "id": "A0A4X1T166", "url": "https://omabrowser.org/oma/group/A0A4X1T166/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1QJN9-1", "protein_name": "Carboxypeptidase B", "gene_name": "cpb1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKLFLLLGLVAVALCEPITFVGDKVLQLKPINDEHVTIIRELGEKIKLDFWKPRSADLVSIDMTVDIHVPAAQLAMVSTILQQSDMEVKVMIDNLQEAVKGQMDNRSPTKGHDYTKYNSWATINDWAISISSANPDLISRQSIGNTYEGRTMHLLKIGKNTGSNKPAVFMDCGFHAREWITHAFCQWFVNEAVSTYGSDPDMTNLLDRMDFFVLPVFNIDGYEYTWNRDRMWRKTRSKNSGSSCIGTDPNRNFNAGWCTVGASSNPCSDTYCGSSPESEIESKNLANFIRTNKSVIKAYLTVHSYSQLLLFPYSYKYDLAAHHSELMSVSQGAIAALRSLYGTKYTSGPGAATIYPAAGGSDDWAYDLGVKYSYTFELRDEGRYGFLLPESQIKPTCEETMLAVKYIANHVLNNLY", "length": 416 }, "evidence": [ { "id": "A0A4X1T166", "url": "https://omabrowser.org/oma/group/A0A4X1T166/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P09955-1", "protein_name": "Carboxypeptidase B", "gene_name": "CPB1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLAFLILVTVTLASAHHSGEHFEGEKVFRVNVEDENDISLLHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVEDFLEQNELQYEVLINNLRSVLEAQFDSRVRTTGHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL", "length": 416 }, "evidence": [ { "id": "A0A4X1T166", "url": "https://omabrowser.org/oma/group/A0A4X1T166/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P15086-1", "protein_name": "Carboxypeptidase B", "gene_name": "CPB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY", "length": 417 }, "evidence": [ { "id": "A0A4X1T166", "url": "https://omabrowser.org/oma/group/A0A4X1T166/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P19223-1", "protein_name": "Carboxypeptidase B", "gene_name": "Cpb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLLALVSVALAHASEEHFDGNRVYRVSVHGEDHVNLIQELANTKEIDFWKPDSATQVKPLTTVDFHVKAEDVADVENFLEENEVHYEVLISNVRNALESQFDSHTRASGHSYTKYNKWETIEAWIQQVATDNPDLVTQSVIGTTFEGRNMYVLKIGKTRPNKPAIFIDCGFHAREWISPAFCQWFVREAVRTYNQEIHMKQLLDELDFYVLPVVNIDGYVYTWTKDRMWRKTRSTMAGSSCLGVRPNRNFNAGWCEVGASRSPCSETYCGPAPESEKETKALADFIRNNLSTIKAYLTIHSYSQMMLYPYSYDYKLPENYEELNALVKGAAKELATLHGTKYTYGPGATTIYPAAGGSDDWSYDQGIKYSFTFELRDTGFFGFLLPESQIRQTCEETMLAVKYIANYVREHLY", "length": 415 }, "evidence": [ { "id": "A0A4X1T166", "url": "https://omabrowser.org/oma/group/A0A4X1T166/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T166", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T166", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T166", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T166", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T166", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T166", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T166" }, { "id": "PS52035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M14", "eco_id": "ECO_0000259", "start_pos": 118, "end_pos": 412, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 293, "end_pos": 295 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T1J4-1", "uniprot_ac": "A0A4X1T1J4", "uniprot_id": "A0A4X1T1J4_PIG", "mass": { "chemical_mass": 35366.0, "monoisotopic_mass": 35366.0 }, "refseq": { "ac": "XP_020924540", "name": "olfactory receptor 5H8-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924540" }, "gene_names": [ { "name": "LOC110256238", "type": "recommended", "evidence": [ { "id": "A0A4X1T1J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4" } ] }, { "name": "LOC110256238", "type": "synonym", "evidence": [ { "id": "XP_020924540", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924540" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1T1J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5H8-like", "type": "synonym", "evidence": [ { "id": "XP_020924540", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924540" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110256238", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4", "locus": {} } ], "crossref": [ { "id": "A0A4X1T1J4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T1J4", "database": "AlphaFoldDB", "categories": [] }, { "id": "110256238", "url": "https://www.ncbi.nlm.nih.gov/gene/110256238", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110256238", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110256238", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MTCSEDM", "url": "https://omabrowser.org/oma/group/MTCSEDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T1J4", "url": "https://www.orthodb.org/?gene=A0A4X1T1J4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020924540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924540", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T1J4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAQNATELTEFVLTGLKYQSEWQIPLFLLFLIIYLITLIGNLGLIALICNDPHLHIPMYLFLGNLAFVDTWLSSTVTPNMLVNFFAKSKMISFSECVVQFFSFALCVTTECFLLATMAYDRYVAICKPLLYPVIMTNRLCIWLLVLSFLGGLFHAILHNTFLFRLTFCDSIIIHHFYCDIIPLFKISCTDPSINYLMLFIFAGIIQALTISTVLVSYTLILFTILKKRSLQGIRKAFSTCGAHLLSVSLYYGPLLFMYVLPGSAQENDQDMMDSLFYTVIIPFLNPIIYSLRNKKVIDSLTKMFKRNI", "length": 309, "header": "tr|A0A4X1T1J4-1|A0A4X1T1J4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110256238 PE=3 SV=1 CANONICAL=A0A4X1T1J4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T1J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4/entry#A0A4X1T1J4-1", "sequence": { "sequence": "MEAQNATELTEFVLTGLKYQSEWQIPLFLLFLIIYLITLIGNLGLIALICNDPHLHIPMYLFLGNLAFVDTWLSSTVTPNMLVNFFAKSKMISFSECVVQFFSFALCVTTECFLLATMAYDRYVAICKPLLYPVIMTNRLCIWLLVLSFLGGLFHAILHNTFLFRLTFCDSIIIHHFYCDIIPLFKISCTDPSINYLMLFIFAGIIQALTISTVLVSYTLILFTILKKRSLQGIRKAFSTCGAHLLSVSLYYGPLLFMYVLPGSAQENDQDMMDSLFYTVIIPFLNPIIYSLRNKKVIDSLTKMFKRNI", "length": 309, "header": "tr|A0A4X1T1J4-1|A0A4X1T1J4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110256238 PE=3 SV=1 CANONICAL=A0A4X1T1J4-1" }, "locus": { "chromosome": "13", "start_pos": 161348938, "end_pos": 161348012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105721.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105721.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075809.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075809.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110256238", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110256238", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LCW8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100766954", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "METKNVTLLTQFVLTGLTHPPQWRIPLFLLFLVIYLITMLGNIGLITLICNDPGLHIPMYLFLGSLAFVDTWLSSTVTPKMLLDFFDRSKMISLSECMLQFFSFVVSATTECFLLAAMAYDRYIAICKPLLYPVIMTNKLCTCLLTLSFVGGFIHALIHESFLLRLTFCNSNVIYHFYCDVMPLLKISCTDPSLNYLMLFIFSGSIQVFTITTILVSYTLVLLSILKQKSIKGIKKAFSTCGAHLLSVSLYYGPLLFMYVRPASPQVDDDDMMDSVFYTVIIPVLNPIIYSLRNKQVKKSLQKFLKRNA", "length": 309 }, "evidence": [ { "id": "A0A4X1T1J4", "url": "https://omabrowser.org/oma/group/A0A4X1T1J4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "L7N1Z8-1", "protein_name": "Olfactory receptor", "gene_name": "Or5h23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METDNTTLLIQFVLSGLVHLPQWKIPLFLLFLVIYLITIVGNLGLIILIWNDPHLHIPMYLFLGCLAFVDTWLSSTVTPKMLQDIFSKSKLISFSECMIQFFSFVVSATTECFLLAAMAYDRYVAICKPLLYPVIMTNRLCVSLLTLSFLGGFIHALIHEGFLFRLIFCRSHIINHFYCDVMPLLKISCNDPSINYLMLFIFSGSIQVFTITTILVSYTLVLFSILKKKSLKSIKKAFSTCGAHLLSVSLYYGPLLFMYVRPASPQVNDEDMMDSVFYTIIIPVLNPIIYSLRNEQVKKSLAKCLRRNT", "length": 309 }, "evidence": [ { "id": "A0A4X1T1J4", "url": "https://omabrowser.org/oma/group/A0A4X1T1J4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T1J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T1J7-1", "uniprot_ac": "A0A4X1T1J7", "uniprot_id": "A0A4X1T1J7_PIG", "mass": { "chemical_mass": 64519.0, "monoisotopic_mass": 64519.0 }, "refseq": { "ac": "XP_003122959", "name": "vesicular glutamate transporter 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122959" }, "gene_names": [ { "name": "SLC17A6", "type": "recommended", "evidence": [ { "id": "A0A4X1T1J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ] }, { "name": "SLC17A6", "type": "synonym", "evidence": [ { "id": "XP_003122959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122959" } ] } ], "protein_names": [ { "name": "Solute carrier family 17 member 6", "type": "synonym", "evidence": [ { "id": "A0A4X1T1J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7/entry#names_and_taxonomy" } ] }, { "name": "vesicular glutamate transporter 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003122959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122959" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC17A6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7", "locus": { "chromosome": "2", "start_pos": 37098992, "end_pos": 37138475, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013343", "url": "https://www.ensembl.org/id/ENSSSCG00000013343" } ] } } ], "crossref": [ { "id": "A0A4X1T1J7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T1J7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17382", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17382", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519886", "url": "https://www.ncbi.nlm.nih.gov/gene/100519886", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519886", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519886", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YNEQSQM", "url": "https://omabrowser.org/oma/group/YNEQSQM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T1J7", "url": "https://www.orthodb.org/?gene=A0A4X1T1J7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11662", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11662", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11662:SF201", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11662:SF201", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-442660", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-442660", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003122959", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122959", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29467", "url": "https://www.rhea-db.org/rhea/29467", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "32823", "url": "https://www.rhea-db.org/rhea/32823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "66336", "url": "https://www.rhea-db.org/rhea/66336", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71255", "url": "https://www.rhea-db.org/rhea/71255", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESVKQRILAPGKEGLKNFAGKSLGQIYRVLEKKQETGETIELTEDGKPLEVPEKKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMIWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYAIFASGEKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATTQANGGWPNGWEKKEEFVQEEAQDSYTYKDRNDYS", "length": 582, "header": "tr|A0A4X1T1J7-1|A0A4X1T1J7_PIG Isoform 1 of Solute carrier family 17 member 6 OS=Sus scrofa OX=9823 GN=SLC17A6 PE=3 SV=1 CANONICAL=A0A4X1T1J7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T1J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7/entry#A0A4X1T1J7-1", "sequence": { "sequence": "MESVKQRILAPGKEGLKNFAGKSLGQIYRVLEKKQETGETIELTEDGKPLEVPEKKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMIWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYAIFASGEKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATTQANGGWPNGWEKKEEFVQEEAQDSYTYKDRNDYS", "length": 582, "header": "tr|A0A4X1T1J7-1|A0A4X1T1J7_PIG Isoform 1 of Solute carrier family 17 member 6 OS=Sus scrofa OX=9823 GN=SLC17A6 PE=3 SV=1 CANONICAL=A0A4X1T1J7-1" }, "locus": { "chromosome": "2", "start_pos": 37137777, "end_pos": 37100785, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014571.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014571.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014176.2", "url": "https://www.ensembl.org/id/ENSSSCP00000014176.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519886", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519886", "resource": "KEGG Pathway" }, { "id": "R-SSC-442660", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-442660", "resource": "Reactome", "description": "SLC-mediated transport of neurotransmitters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7K5H0-1", "protein_name": "Vesicular glutamate transporter 2 isoform X2", "gene_name": "Slc17a6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESVKQRILAPGKEGIKNFAGKSLGQIYRRVLEKKQDTRETIELTEDGKPLEVPEKKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYAIFASGEKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATTQENGGWPNGWEKKEEFVQEGAQDAYTYKDQDDYS", "length": 583 }, "evidence": [ { "id": "A0A4X1T1J7", "url": "https://omabrowser.org/oma/group/A0A4X1T1J7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A6QLI1-1", "protein_name": "Vesicular glutamate transporter 2", "gene_name": "SLC17A6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESVKQRILTPGKEGLKNFAGKSLGQIYRVLEKKQDAGETIELTEDGKPLEVPEKKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMIWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYAIFASGEKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATTQANGGWPNGWEKKEEFVQEEVQNSYNYKDRDDYS", "length": 582 }, "evidence": [ { "id": "A0A4X1T1J7", "url": "https://omabrowser.org/oma/group/A0A4X1T1J7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3E9A0-1", "protein_name": "Probable anion transporter 6, chloroplastic", "gene_name": "ANTR6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MARLTLRPHNHFFSSPIYAHKQPFLSVYTIFPHHHQNPLIKSRVKCSASGTERVRESKKLPPKDPIEDPKPQLPIPEVLSTETGFEQNWPPWKNIPQRYKLIGATSLAFVICNMDKVNLSIAIIPMSHQFGWSSSVAGLVQSSFFWGYALSQLPGGWLSKIFGGRKVLEIGVFTWSFATALVPLLAGFMPGLIFSRILVGIGEGVSPSAATDLIARTIPVKERSRAVGFVFGGLSLGSVMGLLLAPPIIETFNWESVFYLFGLLGVGWFVGFQFLNEEEVSYKGNEISTSHKSENATKEELGSSLKEIPWKSFFQSPAVWAMIYTHFCGSWGHYTCLSWLPTYFSEALSLNLTEAAWVSILPPLASIVVTSLASQFADYLITNGVDTTTVRKICQTIAFVAPAICMTLSSVDIGLPPWEIVGILTAGLALSSFALSGLYCTHQDISPEYASILLGITNTVGAVPGIVGVALTGFLLDSTHSWTMSLFVPSIFFYLTGTVVWLAFASSEPQTFRKEDS", "length": 517 }, "evidence": [ { "id": "A0A4X1T1J7", "url": "https://omabrowser.org/oma/group/A0A4X1T1J7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q5W8I8-1", "protein_name": "Vesicular glutamate transporter 2.1", "gene_name": "slc17a6b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METPREPAGFSKEGLKQLAGKTLGHVYRVIEKRQKPGENIELTEDGRPAQINERKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTIHLNGKIIIKEKAKFNWDPETVGLIHGSFFWGYIVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIPSAARGHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGCFGIFWYMFWILVSYESPAEHPTITAEERCYIEESIGESAKLLGPADKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSALPHLVMTIIVPIGGQLADHLRSKNILSTTTVRKIMNCGGFGMEATLLLIVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQYVFLIASLVHYGGVIFYGIFASGEKQPWADPELTSDEKCGFIDEDELAEETGDITQSYGALGAPAKSYGATTQLNGGWAEGWDKREEYVQDGVEEGGYGYRQGGNYS", "length": 584 }, "evidence": [ { "id": "A0A4X1T1J7", "url": "https://omabrowser.org/oma/group/A0A4X1T1J7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BLE7-1", "protein_name": "Vesicular glutamate transporter 2", "gene_name": "Slc17a6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESVKQRILAPGKEGIKNFAGKSLGQIYRVLEKKQDNRETIELTEDGKPLEVPEKKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISDGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYALFASGEKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATSQENGGWPNGWEKKEEFVQEGAQDAYTYKDRDDYS", "length": 582 }, "evidence": [ { "id": "A0A4X1T1J7", "url": "https://omabrowser.org/oma/group/A0A4X1T1J7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JI12-1", "protein_name": "Vesicular glutamate transporter 2", "gene_name": "Slc17a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESVKQRILAPGKEGIKNFAGKSLGQIYRVLEKKQDNRETIELTEDGKPLEVPEKKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYALFASGEKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATSQENGGWPNGWEKKEEFVQESAQDAYSYKDRDDYS", "length": 582 }, "evidence": [ { "id": "A0A4X1T1J7", "url": "https://omabrowser.org/oma/group/A0A4X1T1J7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9P2U8-1", "protein_name": "Vesicular glutamate transporter 2", "gene_name": "SLC17A6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESVKQRILAPGKEGLKNFAGKSLGQIYRVLEKKQDTGETIELTEDGKPLEVPERKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYAIFASGEKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATTQANGGWPSGWEKKEEFVQGEVQDSHSYKDRVDYS", "length": 582 }, "evidence": [ { "id": "A0A4X1T1J7", "url": "https://omabrowser.org/oma/group/A0A4X1T1J7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VQC0-1", "protein_name": "Vesicular glutamate transporter, isoform A", "gene_name": "VGlut1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKGLTAFKEKATGVFGGLKPNMEKFEISQSYHGGHGGYEEMEGGDREGRGPGGGHAYDDDDDRPDSPASFEEIERPPLRKIDKYCKAECPCMPARYTIATMACVGFMIAFGMRCNMSAAKLKGEHNGTVFMNWTVAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIFGLSIVSSATLHLFVPFAMTLMHGHVVICVRVLQGLFEGVTYPACHGIWRFWAPPMERSRLATLAFSGSYAGVVVGLPLSGLLADAVGYQAPFYAYGVFGIIWYMFWIWLCFENPRKHPAISIPELKYIEKSLGESAHPTMPSLKTTPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADHLRKNGILSTTNVRKLFNCGGFGMEGLFFLFVAHSSTATGAMFALTCGVAFSGFAISGYNVNHLDIAPRYASILMGLSNGIGTLAGIIVPYALDGLIQANPTGCWTTVFTLAACVHLVGCTFYGIFASGELQPWAEPPAEEQKVWAPPPGAITNTDPSQAGMLGDYMKETSFGAPEYTEQSQMQQSTAISYGATGHVANNPFAMASGAPPIAEEDAPPTYGDVTNPGQYGYTQGQMPSYDPQGYQQQ", "length": 632 }, "evidence": [ { "id": "A0A4X1T1J7", "url": "https://omabrowser.org/oma/group/A0A4X1T1J7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "neurotransmitter transmembrane transporter activity", "id": "GO:0005326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005326", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transporter activity", "id": "GO:0005313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005313", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "L-glutamate uniporter activity", "id": "GO:0140788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140788", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "excitatory synapse", "id": "GO:0060076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060076", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of synapse structure or activity", "id": "GO:0050803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050803", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "phosphate ion homeostasis", "id": "GO:0055062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055062", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "phosphate ion transport", "id": "GO:0006817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006817", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" }, { "name": "neurotransmitter loading into synaptic vesicle", "id": "GO:0098700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098700", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1J7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29467", "name": "", "equation": "K(+)(in) + H(+)(out) = K(+)(out) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29467", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29467" } ] }, { "id": "29823", "name": "", "equation": "chloride(in) = chloride(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29823", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29823" } ] }, { "id": "32823", "name": "", "equation": "phosphate(in) = phosphate(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "32823", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32823" } ] }, { "id": "66336", "name": "", "equation": "L-glutamate(out) = L-glutamate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "66336", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/66336" } ] }, { "id": "71255", "name": "", "equation": "3 Na(+)(out) + phosphate(out) = 3 Na(+)(in) + phosphate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71255", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71255" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T1J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1J7" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 502, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 101, "end_pos": 103 }, { "start_pos": 470, "end_pos": 472 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T1T4-1", "uniprot_ac": "A0A4X1T1T4", "uniprot_id": "A0A4X1T1T4_PIG", "mass": { "chemical_mass": 26535.0, "monoisotopic_mass": 26535.0 }, "refseq": {}, "gene_names": [ { "name": "IDI1", "type": "recommended", "evidence": [ { "id": "A0A4X1T1T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ] } ], "protein_names": [ { "name": "isopentenyl-diphosphate Delta-isomerase", "type": "recommended", "evidence": [ { "id": "A0A4X1T1T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4/entry#names_and_taxonomy" } ] }, { "name": "5.3.3.2", "type": "synonym", "evidence": [ { "id": "A0A4X1T1T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQB3#function" }, { "database": "UniProtKB", "id": "ARBA00003951", "url": "https://www.uniprot.org/uniprotkb/ARBA00003951#function" }, { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IDI1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4", "locus": { "chromosome": "10", "start_pos": 68539280, "end_pos": 68534796, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000029066", "url": "https://www.ensembl.org/id/ENSSSCG00000029066" } ] } } ], "crossref": [ { "id": "A0A4X1T1T4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T1T4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02885", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02885", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000086", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000086", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10885", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10885", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10885:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10885:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00293", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00293", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9969896", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9969896", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "23284", "url": "https://www.rhea-db.org/rhea/23284", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEINTDHLDAQQVQLLAEMCILIDENDRRIGAETKKNCHLNENIKKGLLHRAFSVFLFNTENKLLLQQRSDAKITFPGCFSNACCSHPLSTPGELEENDAIGVRRAAQRRLKAELGIPLEEVPPEEINYLTRIYYKAQSDGIWGEHEIDYILLMKKDVTLNPDPNEIKSHCYVSQEELKELLRKAARGEVKVTPWFQMIADRFLFHWWDNLNHWNQFVDHEKIHRM", "length": 227, "header": "tr|A0A4X1T1T4-1|A0A4X1T1T4_PIG Isoform 1 of isopentenyl-diphosphate Delta-isomerase OS=Sus scrofa OX=9823 GN=IDI1 PE=1 SV=1 CANONICAL=A0A4X1T1T4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T1T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4/entry#A0A4X1T1T4-1", "sequence": { "sequence": "MPEINTDHLDAQQVQLLAEMCILIDENDRRIGAETKKNCHLNENIKKGLLHRAFSVFLFNTENKLLLQQRSDAKITFPGCFSNACCSHPLSTPGELEENDAIGVRRAAQRRLKAELGIPLEEVPPEEINYLTRIYYKAQSDGIWGEHEIDYILLMKKDVTLNPDPNEIKSHCYVSQEELKELLRKAARGEVKVTPWFQMIADRFLFHWWDNLNHWNQFVDHEKIHRM", "length": 227, "header": "tr|A0A4X1T1T4-1|A0A4X1T1T4_PIG Isoform 1 of isopentenyl-diphosphate Delta-isomerase OS=Sus scrofa OX=9823 GN=IDI1 PE=1 SV=1 CANONICAL=A0A4X1T1T4-1" }, "locus": { "chromosome": "10", "start_pos": 68537448, "end_pos": 68535120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024912.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024912.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025683.2", "url": "https://www.ensembl.org/id/ENSSSCP00000025683.2" } ] } }, { "isoform_ac": "A0A8W4FQB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4/entry#A0A8W4FQB3-1", "sequence": { "sequence": "MPEINTDHLDAQQVQLLAEMCILIDENDRRIGAETKKNCHLNENIKKGACAAGAVLLTSRRLPSDGRPGGAQGCFSNACCSHPLSTPGELEENDAIGVRRAAQRRLKAELGIPLEEVPPEEINYLTRIYYKAQSDGIWGEHEIDYILLMKKDVTLNPDPNEIKSHCYVSQEELKELLRKAARGEVKVTPWFQMIADRFLFHWWDNLNHWNQFVDHEKIHRM", "length": 221, "header": "tr|A0A8W4FQB3-1|A0A4X1T1T4_PIG Computationally mapped isoform of isopentenyl-diphosphate Delta-isomerase OS=Sus scrofa OX=9823 GN=IDI1 PE=1 SV=1 CANONICAL=A0A4X1T1T4-1" }, "locus": { "chromosome": "10", "start_pos": 68537448, "end_pos": 68535120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093132.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093132.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080552.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080552.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQB3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9969896", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9969896", "resource": "Reactome", "description": "Lanosterol biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "isopentenyl-diphosphate delta-isomerase activity", "id": "GO:0004452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004452", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "isopentenyl diphosphate biosynthetic process", "id": "GO:0009240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009240", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" }, { "name": "dimethylallyl diphosphate biosynthetic process", "id": "GO:0050992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050992", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" }, { "name": "response to stilbenoid", "id": "GO:0035634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" }, { "name": "geranylgeranyl diphosphate biosynthetic process", "id": "GO:0033386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033386", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process via desmosterol", "id": "GO:0033489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033489", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process via lathosterol", "id": "GO:0033490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033490", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" }, { "name": "farnesyl diphosphate biosynthetic process, mevalonate pathway", "id": "GO:0010142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010142", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" }, { "name": "zymosterol biosynthetic process", "id": "GO:0036197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036197", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process", "id": "GO:0006695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006695", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" }, { "name": "isoprenoid biosynthetic process", "id": "GO:0008299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008299", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23284", "name": "", "equation": "isopentenyl diphosphate = dimethylallyl diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "23284", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23284" } ] }, { "id": "R-SSC-191382", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-191382", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-191382" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T1T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T4" }, { "id": "PS51462", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51462" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nudix hydrolase", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 199, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T1T6-1", "uniprot_ac": "A0A4X1T1T6", "uniprot_id": "A0A4X1T1T6_PIG", "mass": { "chemical_mass": 37981.0, "monoisotopic_mass": 37981.0 }, "refseq": { "ac": "XP_020958183", "name": "solute carrier family 25 member 40", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958183" }, "gene_names": [ { "name": "SLC25A40", "type": "recommended", "evidence": [ { "id": "A0A4X1T1T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6" } ] }, { "name": "SLC25A40", "type": "synonym", "evidence": [ { "id": "XP_020958183", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958183" } ] } ], "protein_names": [ { "name": "Mitochondrial glutathione transporter SLC25A40", "type": "recommended", "evidence": [ { "id": "A0A4X1T1T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 25 member 40", "type": "synonym", "evidence": [ { "id": "A0A4X1T1T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 25 member 40", "type": "synonym", "evidence": [ { "id": "XP_020958183", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958183" } ] } ], "function": [ { "annotation": "Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0U8W9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0U8W9#function" }, { "database": "UniProtKB", "id": "RU369018", "url": "https://www.uniprot.org/uniprotkb/RU369018#function" }, { "database": "UniProtKB", "id": "A0A5G2QVF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF7#function" }, { "database": "UniProtKB", "id": "A0A4X1T1T6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6#function" }, { "database": "UniProtKB", "id": "A0A5G2REX5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REX5#function" } ] }, { "annotation": "Probable mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6#function" }, { "database": "UniProtKB", "id": "ARBA00056326", "url": "https://www.uniprot.org/uniprotkb/ARBA00056326#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC25A40", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6", "locus": { "chromosome": "9", "start_pos": 92528186, "end_pos": 92481564, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026177", "url": "https://www.ensembl.org/id/ENSSSCG00000026177" } ] } } ], "crossref": [ { "id": "ENSSSCG00000026177", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026177", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100621546", "url": "https://www.ncbi.nlm.nih.gov/gene/100621546", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621546", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621546", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YWWGYES", "url": "https://omabrowser.org/oma/group/YWWGYES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T1T6", "url": "https://www.orthodb.org/?gene=A0A4X1T1T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45760:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45760:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020958183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958183", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "74819", "url": "https://www.rhea-db.org/rhea/74819", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T1T6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T1T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVF7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REX5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0U8W9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0U8W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0U8W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0U8W9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPEAEGPAIITVTPLQQMLASCTGAILTSLMVTPFDVVKIRLQAQNNPFSKGKCFVYSNGLMDHLCICEEEGNKAWYKKPGRFQGTLDAFLKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLTALLRSKLGENESSIPVVAGIVARLGAVTVISPLELIRTKMQSKTFSYKELHQFVSRKVSEDGWISLWRGWAPTVLRDVPFSALYWYNYEVLKKWLCAKSGLYEPTFMITFTSGALSGSFAAVVTLPFDVVKTQKQTQLWTYESHKISMPWQMSTWAIMKNIVAKDGFSGLFTGLIPRLIKIAPACAIMISTYEFGKSFFQKQNARRQQY", "length": 338, "header": "tr|A0A4X1T1T6-1|A0A4X1T1T6_PIG Isoform 1 of Mitochondrial glutathione transporter SLC25A40 OS=Sus scrofa OX=9823 GN=SLC25A40 PE=1 SV=1 CANONICAL=A0A4X1T1T6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T1T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6/entry#A0A4X1T1T6-1", "sequence": { "sequence": "MDPEAEGPAIITVTPLQQMLASCTGAILTSLMVTPFDVVKIRLQAQNNPFSKGKCFVYSNGLMDHLCICEEEGNKAWYKKPGRFQGTLDAFLKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLTALLRSKLGENESSIPVVAGIVARLGAVTVISPLELIRTKMQSKTFSYKELHQFVSRKVSEDGWISLWRGWAPTVLRDVPFSALYWYNYEVLKKWLCAKSGLYEPTFMITFTSGALSGSFAAVVTLPFDVVKTQKQTQLWTYESHKISMPWQMSTWAIMKNIVAKDGFSGLFTGLIPRLIKIAPACAIMISTYEFGKSFFQKQNARRQQY", "length": 338, "header": "tr|A0A4X1T1T6-1|A0A4X1T1T6_PIG Isoform 1 of Mitochondrial glutathione transporter SLC25A40 OS=Sus scrofa OX=9823 GN=SLC25A40 PE=1 SV=1 CANONICAL=A0A4X1T1T6-1" }, "locus": { "chromosome": "9", "start_pos": 92524980, "end_pos": 92497971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060095.2", "url": "https://www.ensembl.org/id/ENSSSCT00000060095.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032685.1", "url": "https://www.ensembl.org/id/ENSSSCP00000032685.1" } ] } }, { "isoform_ac": "A0A5G2QVF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6/entry#A0A5G2QVF7-1", "sequence": { "sequence": "MDPEAEGPAIITVTPLQQMLASCTGAILTSLMVTPFDVVKIRLQAQNNPFSKGKCFVYSNGLMDHLCICEEEGNKAWYKKPGRFQGTLDAFLKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLTALLRSKLGENESSIPVVAGIVARLGAVTVISPLELIRTKMQSKTFSYKELHQFVSRKVSEDGWISLWRGWAPTVLRDVPFSALYWYNYEVLKKWLCAKSGLYEPTFMITFTSGALSGSFAAVVTLPFDVVKTQKQTQLWTYESHKISMPWQMSTWAIMKNIVAKDGFSGLFTGKIISFTKSSTT", "length": 313, "header": "tr|A0A5G2QVF7-1|A0A4X1T1T6_PIG Computationally mapped isoform of Mitochondrial glutathione transporter SLC25A40 OS=Sus scrofa OX=9823 GN=SLC25A40 PE=1 SV=1 CANONICAL=A0A4X1T1T6-1" }, "locus": { "chromosome": "9", "start_pos": 92524535, "end_pos": 92497971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085669.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085669.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068833.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068833.1" } ] } }, { "isoform_ac": "A0A5G2REX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6/entry#A0A5G2REX5-1", "sequence": { "sequence": "MDPEAEGPAIITVTPLQQMLASCTGAILTSLMVTPFDVVKIRLQAQNNPFSKGKCFVYSNGLMDHLCICEEEGNKAWYKKPGRFQGTLDAFLKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLTALLRSKLGENESSIPVVAGIVARLGAVTVISPLELIRTKMQSKTFSYKELHQFVSRKVSEDGWISLWRGWAPTVLRDVPFSALYWYNYEVLKKWLCAKSGLYEPTFMITFTSGALSGSFAAVVTLPFDVVKTQKQTQLWTYESHKTYQSSQARGLIGATAASHSHSHARSEMCLRPAPQLTATLDP", "length": 315, "header": "tr|A0A5G2REX5-1|A0A4X1T1T6_PIG Computationally mapped isoform of Mitochondrial glutathione transporter SLC25A40 OS=Sus scrofa OX=9823 GN=SLC25A40 PE=1 SV=1 CANONICAL=A0A4X1T1T6-1" }, "locus": { "chromosome": "9", "start_pos": 92521751, "end_pos": 92497971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077856.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077856.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073251.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073251.1" } ] } }, { "isoform_ac": "A0A8D0U8W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6/entry#A0A8D0U8W9-1", "sequence": { "sequence": "MDPEAEGPAIITVTPLQQMLASCTGAILTSLMGKCFVYSNGLMDHLCICEEEGNKAWYKKPGRFQGTLDAFLKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLTALLRSKLGENESSIPVVAGIVARLGAVTVISPLELIRTKMQSKTFSYKELHQFVSRKVSEDGWISLWRGWAPTVLRDVPFSALYWYNYEVLKKWLCAKSGLYEPTFMITFTSGALSGSFAAVVTLPFDVVKTQKQTQLWTYESHKISMPWQMSTWAIMKNIVAKDGFSGLFTGLIPRLIKIAPACAIMISTYEFGKSFFQKQNARRQQY", "length": 318, "header": "tr|A0A8D0U8W9-1|A0A4X1T1T6_PIG Computationally mapped isoform of Mitochondrial glutathione transporter SLC25A40 OS=Sus scrofa OX=9823 GN=SLC25A40 PE=1 SV=1 CANONICAL=A0A4X1T1T6-1" }, "locus": { "chromosome": "9", "start_pos": 92524980, "end_pos": 92497971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028088.3", "url": "https://www.ensembl.org/id/ENSSSCT00000028088.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020586.2", "url": "https://www.ensembl.org/id/ENSSSCP00000020586.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0U8W9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0U8W9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621546", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621546", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P53320-1", "protein_name": "Mitochondrial carrier protein MTM1", "gene_name": "MTM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDRNTSNSLTLKERMLSAGAGSVLTSLILTPMDVVRIRLQQQQMIPDCSCDGAAEVPNAVSSGSKMKTFTNVGGQNLNNAKIFWESACFQELHCKNSSLKFNGTLEAFTKIASVEGITSLWRGISLTLLMAIPANMVYFSGYEYIRDVSPIASTYPTLNPLFCGAIARVFAATSIAPLELVKTKLQSIPRSSKSTKTWMMVKDLLNETRQEMKMVGPSRALFKGLEITLWRDVPFSAIYWSSYELCKERLWLDSTRFASKDANWVHFINSFASGCISGMIAAICTHPFDVGKTRWQISMMNNSDPKGGNRSRNMFKFLETIWRTEGLAALYTGLAARVIKIRPSCAIMISSYEISKKVFGNKLHQ", "length": 366 }, "evidence": [ { "id": "A0A4X1T1T6", "url": "https://omabrowser.org/oma/group/A0A4X1T1T6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0VCH6-1", "protein_name": "Mitochondrial glutathione transporter SLC25A40", "gene_name": "SLC25A40", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPESEGPAVITVTPLQQMFASCTGAILTSLMVTPFDVVKIRLQAQNNPFPKGKCFLYSNGLMDHLCVCEEEGNKAWYKKPGHFQGTLDAFLKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLTALLRSKLGENESRIPIVAGIVARLGAVTVISPLELIRTKMQSKKFSYEELHRFVSKKVSEDGWISLWRGWAPTILRDVPFSAMYWYNYEVLKKWLCAKSGLYEPTFMINFTSGALSGSFAAVVTLPFDVVKTQKQTQLWIYESQKISMPLQMSTWTIMKNIVAKNGFSGLFTGLIPRLIKIAPACAVMISTYEFGKSFFQKQNAQRQRY", "length": 338 }, "evidence": [ { "id": "A0A4X1T1T6", "url": "https://omabrowser.org/oma/group/A0A4X1T1T6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q552L9-1", "protein_name": "Mitochondrial substrate carrier family protein H", "gene_name": "mcfH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSNSVNNNNNNNNINNSNSNNNDSNIHKNVKKLMVASIFGGIMSSLIVTPLDVVKTRLQTQNTGSHINQKHVFKGTLDAFKKIYKNEGPLTFWRGVTPSLLMTIPSATIYFTSYEYLKEYLYQFNDTEAYNIYTVPLVAGTLARIFSASVTSPFELLRTNSQGIVLQNAYKNTVAMAASSSTATIGTIPLSSEQRFNSFKLYRDIVNNVGIKGLWRGLGPTLVRDVPFSAIYWAGYEVLKNKLMKSQIDPNFSRNSKSPFFINFIAGATSGTLAAVLTTPIDVIKTRIQMSAQQTLSPSLTPQQQLDFIKKNNSSIYHLKQILSQEGWKGLTKGLVPRVAKVSPACAIMISTFEYIKQSHIADDN", "length": 366 }, "evidence": [ { "id": "A0A4X1T1T6", "url": "https://omabrowser.org/oma/group/A0A4X1T1T6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6DHC3-1", "protein_name": "Mitochondrial glutathione transporter SLC25A40", "gene_name": "slc25a40", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSCQESSPGPPGDITPFQQMMASCSGAIITSLLVTPLDVVKIRLQAQKNPFPKGKCFVYCNGLMDHICVCENGNTKVWYKAPGHFSGTLDAFLKIIRMEGIRSLWSGLPPTLIMAVPATVIYFTCYDQLFALLKLKMGDRSDLAPLFAGAIARVGSATVISPLELIRTKMQSEKQSYREMSAVIRSALKNEGLRSLWRGWGPTLLRDVPFSAMYWFNYEKGKWWLCKRYSCSEPTVAITFTAGALSGSIASIITLPFDVVKTKRQVEMGELQTMKLSTQVSSSTCSVMKRIVAENGVSGLFAGFMPRLIKVAPACAIMISTYEFGKAFFRKYNHQKEGQATASQHIISHTEKH", "length": 353 }, "evidence": [ { "id": "A0A4X1T1T6", "url": "https://omabrowser.org/oma/group/A0A4X1T1T6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8TBP6-1", "protein_name": "Mitochondrial glutathione transporter SLC25A40", "gene_name": "SLC25A40", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPETRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRRQQY", "length": 338 }, "evidence": [ { "id": "A0A4X1T1T6", "url": "https://omabrowser.org/oma/group/A0A4X1T1T6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glutathione transmembrane transporter activity", "id": "GO:0034634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial transmembrane transport", "id": "GO:1990542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990542", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T1T6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T1T6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "74819", "name": "", "equation": "glutathione(in) = glutathione(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "74819", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/74819" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T2P1-1", "uniprot_ac": "A0A4X1T2P1", "uniprot_id": "A0A4X1T2P1_PIG", "mass": { "chemical_mass": 11078.0, "monoisotopic_mass": 11078.0 }, "refseq": {}, "gene_names": [ { "name": "RPL37", "type": "recommended", "evidence": [ { "id": "A0A4X1T2P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1" } ] } ], "protein_names": [ { "name": "Ribosomal protein L37", "type": "recommended", "evidence": [ { "id": "A0A4X1T2P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9N9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9N9#function" }, { "database": "UniProtKB", "id": "RU000576", "url": "https://www.uniprot.org/uniprotkb/RU000576#function" }, { "database": "UniProtKB", "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1#function" }, { "database": "UniProtKB", "id": "ARBA00034092", "url": "https://www.uniprot.org/uniprotkb/ARBA00034092#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPL37", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1", "locus": { "chromosome": "16", "start_pos": 25797120, "end_pos": 25803526, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000033326", "url": "https://www.ensembl.org/id/ENSSSCG00000033326" } ] } } ], "crossref": [ { "id": "A0A4X1T2P1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T2P1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000033326", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033326", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RMAYLKH", "url": "https://omabrowser.org/oma/group/RMAYLKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10768", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10768", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10768:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10768:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10768:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10768:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T2P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9N9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9N9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "length": 97, "header": "tr|A0A4X1T2P1-1|A0A4X1T2P1_PIG Isoform 1 of Ribosomal protein L37 OS=Sus scrofa OX=9823 GN=RPL37 PE=3 SV=1 CANONICAL=A0A4X1T2P1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T2P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1/entry#A0A4X1T2P1-1", "sequence": { "sequence": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "length": 97, "header": "tr|A0A4X1T2P1-1|A0A4X1T2P1_PIG Isoform 1 of Ribosomal protein L37 OS=Sus scrofa OX=9823 GN=RPL37 PE=3 SV=1 CANONICAL=A0A4X1T2P1-1" }, "locus": { "chromosome": "16", "start_pos": 25803488, "end_pos": 25800933, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047002.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047002.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048476.1", "url": "https://www.ensembl.org/id/ENSSSCP00000048476.1" } ] } }, { "isoform_ac": "A0A5G2R9N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1/entry#A0A5G2R9N9-1", "sequence": { "sequence": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKCMDSVKEQHLNPRGQLLRHPVHLKDFS", "length": 73, "header": "tr|A0A5G2R9N9-1|A0A4X1T2P1_PIG Computationally mapped isoform of Ribosomal protein L37 OS=Sus scrofa OX=9823 GN=RPL37 PE=3 SV=1 CANONICAL=A0A4X1T2P1-1" }, "locus": { "chromosome": "16", "start_pos": 25803488, "end_pos": 25800920, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076495.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076495.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073034.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073034.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9N9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9N9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M0S7-1", "protein_name": "Ribosomal protein L37", "gene_name": "Rpl37", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "length": 97 }, "evidence": [ { "id": "A0A4X1T2P1", "url": "https://omabrowser.org/oma/group/A0A4X1T2P1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1C810-1", "protein_name": "Ribosomal protein L37", "gene_name": "RPL37", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKKVYRRFRNGFREGTTPKPKRAAVAASSSS", "length": 97 }, "evidence": [ { "id": "A0A4X1T2P1", "url": "https://omabrowser.org/oma/group/A0A4X1T2P1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P49166-1", "protein_name": "Large ribosomal subunit protein eL37A", "gene_name": "RPL37A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPAAKTRSYNWGAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSASKASA", "length": 88 }, "evidence": [ { "id": "A0A4X1T2P1", "url": "https://omabrowser.org/oma/group/A0A4X1T2P1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P61927-1", "protein_name": "Large ribosomal subunit protein eL37", "gene_name": "RPL37", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "length": 97 }, "evidence": [ { "id": "A0A4X1T2P1", "url": "https://omabrowser.org/oma/group/A0A4X1T2P1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61928-1", "protein_name": "Large ribosomal subunit protein eL37", "gene_name": "Rpl37", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "length": 97 }, "evidence": [ { "id": "A0A4X1T2P1", "url": "https://omabrowser.org/oma/group/A0A4X1T2P1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P79244-1", "protein_name": "Large ribosomal subunit protein eL37", "gene_name": "RPL37", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "length": 97 }, "evidence": [ { "id": "A0A4X1T2P1", "url": "https://omabrowser.org/oma/group/A0A4X1T2P1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54MG6-1", "protein_name": "Large ribosomal subunit protein eL37", "gene_name": "rpl37", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKGTFSFGRRHTKSHTLCRRCGKSSFHIQKKTCASCGYPSAKTRSYNWSIKAQRRKTTGTGRTRYLKTVHKRFNSGFKEASLAVKKTAAK", "length": 91 }, "evidence": [ { "id": "A0A4X1T2P1", "url": "https://omabrowser.org/oma/group/A0A4X1T2P1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8LEM8-1", "protein_name": "Large ribosomal subunit protein eL37x", "gene_name": "RPL37C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGKGTGSFGKRRNKSHTLCVRCGRRSFHIQKSRCSACAYPAARKRTYNWSVKAIRRKTTGTGRMRYLRNVPRRFKTGFREGTEAKPRSKASASSA", "length": 95 }, "evidence": [ { "id": "A0A4X1T2P1", "url": "https://omabrowser.org/oma/group/A0A4X1T2P1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9D823-1", "protein_name": "Large ribosomal subunit protein eL37", "gene_name": "Rpl37", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "length": 97 }, "evidence": [ { "id": "A0A4X1T2P1", "url": "https://omabrowser.org/oma/group/A0A4X1T2P1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VXX8-1", "protein_name": "Large ribosomal subunit protein eL37A", "gene_name": "RpL37-1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTKGTSSFGKRHNKTHTLCRRCGRSSYHIQKSTCAQCGYPAAKLRSYNWSVKAKRRKTTGTGRMQHLKVVRRRFRNGFREGTQAKPKKAVASK", "length": 93 }, "evidence": [ { "id": "A0A4X1T2P1", "url": "https://omabrowser.org/oma/group/A0A4X1T2P1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1" } ], "pmid": "" }, { "name": "MDM2/MDM4 family protein binding", "id": "GO:0097371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097371", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1" } ], "pmid": "" }, { "name": "ubiquitin ligase inhibitor activity", "id": "GO:1990948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990948", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of signal transduction by p53 class mediator", "id": "GO:1901798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901798", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T2P3-1", "uniprot_ac": "A0A4X1T2P3", "uniprot_id": "A0A4X1T2P3_PIG", "mass": { "chemical_mass": 8818.0, "monoisotopic_mass": 8818.0 }, "refseq": {}, "gene_names": [ { "name": "RPLP1", "type": "recommended", "evidence": [ { "id": "A0A4X1T2P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein P1", "type": "recommended", "evidence": [ { "id": "A0A4X1T2P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3/entry#names_and_taxonomy" } ] }, { "name": "60S acidic ribosomal protein P1", "type": "synonym", "evidence": [ { "id": "A0A4X1T2P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays an important role in the elongation step of protein synthesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3#function" }, { "database": "UniProtKB", "id": "ARBA00003362", "url": "https://www.uniprot.org/uniprotkb/ARBA00003362#function" }, { "database": "UniProtKB", "id": "A0A4X1T568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T568#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPLP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3", "locus": { "chromosome": "1", "start_pos": 167298263, "end_pos": 167296094, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004970", "url": "https://www.ensembl.org/id/ENSSSCG00000004970" } ] } } ], "crossref": [ { "id": "A0A4X1T2P3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T2P3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05831", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05831", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100170119", "url": "https://www.ncbi.nlm.nih.gov/gene/100170119", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YSAHDHE", "url": "https://omabrowser.org/oma/group/YSAHDHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T568", "url": "https://www.orthodb.org/?gene=A0A4X1T568", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45696", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45696", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45696:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45696:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T2P3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T2P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T568", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T568-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T568-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASVSELACIYSALILHDDEVTVTALANVNIGSLICNVGAGGPAPAAGAAPAGGPAPATTAAPAEEKKVEAKKEESEESDDDMGFGLFD", "length": 89, "header": "tr|A0A4X1T2P3-1|A0A4X1T2P3_PIG Isoform 1 of Large ribosomal subunit protein P1 OS=Sus scrofa OX=9823 GN=RPLP1 PE=1 SV=1 CANONICAL=A0A4X1T2P3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T2P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3/entry#A0A4X1T2P3-1", "sequence": { "sequence": "MASVSELACIYSALILHDDEVTVTALANVNIGSLICNVGAGGPAPAAGAAPAGGPAPATTAAPAEEKKVEAKKEESEESDDDMGFGLFD", "length": 89, "header": "tr|A0A4X1T2P3-1|A0A4X1T2P3_PIG Isoform 1 of Large ribosomal subunit protein P1 OS=Sus scrofa OX=9823 GN=RPLP1 PE=1 SV=1 CANONICAL=A0A4X1T2P3-1" }, "locus": { "chromosome": "1", "start_pos": 167298218, "end_pos": 167296226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045915.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045915.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050199.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050199.2" } ] } }, { "isoform_ac": "A0A4X1T568-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3/entry#A0A4X1T568-1", "sequence": { "sequence": "MASVSELACIYSALILHDDEVTVTEDKINALIKAAGVNVEPFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGPAPATTAAPAEEKKVEAKKEESEESDDDMGFGLFD", "length": 114, "header": "tr|A0A4X1T568-1|A0A4X1T568_PIG Computationally mapped isoform of Large ribosomal subunit protein P1 OS=Sus scrofa OX=9823 GN=RPLP1 PE=1 SV=1 CANONICAL=A0A4X1T2P3-1" }, "locus": { "chromosome": "1", "start_pos": 167298218, "end_pos": 167296226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005482.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005482.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005345.2", "url": "https://www.ensembl.org/id/ENSSSCP00000005345.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "P05318-1", "protein_name": "Large ribosomal subunit protein P1A", "gene_name": "RPP1A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTESALSYAALILADSEIEISSEKLLTLTNAANVPVENIWADIFAKALDGQNLKDLLVNFSAGAAAPAGVAGGVAGGEAGEAEAEKEEEEAKEESDDDMGFGLFD", "length": 106 }, "evidence": [ { "id": "A0A4X1T2P3", "url": "https://omabrowser.org/oma/group/A0A4X1T2P3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P19944-1", "protein_name": "Large ribosomal subunit protein P1", "gene_name": "Rplp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASVSELACIYSALILHDDEVTVTEDKINALIKAAGVNVEPFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGPAPSAAAAPAEEKKVEAKKEESEESEDDMGFGLFD", "length": 114 }, "evidence": [ { "id": "A0A4X1T2P3", "url": "https://omabrowser.org/oma/group/A0A4X1T2P3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "translational elongation", "id": "GO:0006414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006414", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3" } ], "pmid": "" }, { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2P3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2P3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T2V1-1", "uniprot_ac": "A0A4X1T2V1", "uniprot_id": "A0A4X1T2V1_PIG", "mass": { "chemical_mass": 11954.0, "monoisotopic_mass": 11954.0 }, "refseq": {}, "gene_names": [ { "name": "UCN2", "type": "recommended", "evidence": [ { "id": "A0A4X1T2V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" } ] } ], "protein_names": [ { "name": "Urocortin 2", "type": "synonym", "evidence": [ { "id": "A0A4X1T2V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1#function" }, { "database": "UniProtKB", "id": "ARBA00025160", "url": "https://www.uniprot.org/uniprotkb/ARBA00025160#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UCN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1", "locus": { "chromosome": "13", "start_pos": 31261196, "end_pos": 31261534, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036910", "url": "https://www.ensembl.org/id/ENSSSCG00000036910" } ] } } ], "crossref": [ { "id": "A0A4X1T2V1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T2V1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TWPWAAQ", "url": "https://omabrowser.org/oma/group/TWPWAAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR17575", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17575", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17575:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17575:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-373080", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-373080", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T2V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRWALLVLMILTLARTLLVPANPLPGFQLLPQNFPQVTPCPVTSESPSASTTGPSATWGHPSPGPHPGSRITLSLDVPLGLLQILLEQARARAVREQAAANARILAHVGRR", "length": 112, "header": "tr|A0A4X1T2V1-1|A0A4X1T2V1_PIG Isoform 1 of Urocortin 2 OS=Sus scrofa OX=9823 GN=UCN2 PE=3 SV=1 CANONICAL=A0A4X1T2V1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T2V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1/entry#A0A4X1T2V1-1", "sequence": { "sequence": "MTRWALLVLMILTLARTLLVPANPLPGFQLLPQNFPQVTPCPVTSESPSASTTGPSATWGHPSPGPHPGSRITLSLDVPLGLLQILLEQARARAVREQAAANARILAHVGRR", "length": 112, "header": "tr|A0A4X1T2V1-1|A0A4X1T2V1_PIG Isoform 1 of Urocortin 2 OS=Sus scrofa OX=9823 GN=UCN2 PE=3 SV=1 CANONICAL=A0A4X1T2V1-1" }, "locus": { "chromosome": "13", "start_pos": 31261534, "end_pos": 31261199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036946.2", "url": "https://www.ensembl.org/id/ENSSSCT00000036946.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045074.2", "url": "https://www.ensembl.org/id/ENSSSCP00000045074.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-373080", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-373080", "resource": "Reactome", "description": "Class B/2 (Secretin family receptors)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LSC5-1", "protein_name": "Urocortin-2", "gene_name": "Ucn2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMARWALAVLMVLILGRVLFVPGTPIPTFQLPPQNYSETLPYSMALENHSAATTGTSASWSYSKPKPHLDTQVTLSLDVPIGLLRILLEQARTKAARDQATTNAQILARVGRR", "length": 113 }, "evidence": [ { "id": "A0A4X1T2V1", "url": "https://omabrowser.org/oma/group/A0A4X1T2V1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MKP4-1", "protein_name": "Urocortin 2", "gene_name": "UCN2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTRWALLTLMVLTLGRTLLVPATPTPGFQLLPQNFPQATACPVTSESPSGSTTAPSAAWGRPSPDPHPGPRITLSLDVPLGLLQILLEQARARAVREQAAANARILAQVGRR", "length": 112 }, "evidence": [ { "id": "A0A4X1T2V1", "url": "https://omabrowser.org/oma/group/A0A4X1T2V1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q91WW1-1", "protein_name": "Urocortin-2", "gene_name": "Ucn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRWALVVFMVLMLDRVPGTPIPTFQLLPQNYPETTPSSVSSESPSDTTTGPSASWSNSKASPYLDTRVILSLDVPIGLLRILLEQARNKAARNQAATNAQILARVGRR", "length": 109 }, "evidence": [ { "id": "A0A4X1T2V1", "url": "https://omabrowser.org/oma/group/A0A4X1T2V1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96RP3-1", "protein_name": "Urocortin-2", "gene_name": "UCN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTRCALLLLMVLMLGRVLVVPVTPIPTFQLRPQNSPQTTPRPAASESPSAAPTWPWAAQSHCSPTRHPGSRIVLSLDVPIGLLQILLEQARARAAREQATTNARILARVGHC", "length": 112 }, "evidence": [ { "id": "A0A4X1T2V1", "url": "https://omabrowser.org/oma/group/A0A4X1T2V1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99ML8-1", "protein_name": "Urocortin-2", "gene_name": "Ucn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMTRWALVVFVVLMLDRILFVPGTPIPTFQLLPQNSLETTPSSVTSESSSGTTTGPSASWSNSKASPYLDTRVILSLDVPIGLLRILLEQARYKAARNQAATNAQILAHVGRR", "length": 113 }, "evidence": [ { "id": "A0A4X1T2V1", "url": "https://omabrowser.org/oma/group/A0A4X1T2V1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "corticotropin-releasing hormone receptor binding", "id": "GO:0051429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051429", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" } ], "pmid": "" }, { "name": "hormone binding", "id": "GO:0042562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042562", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" } ], "pmid": "" }, { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" } ], "pmid": "" }, { "name": "corticotropin-releasing hormone receptor 2 binding", "id": "GO:0051431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051431", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" } ], "pmid": "" }, { "name": "hormone-mediated signaling pathway", "id": "GO:0009755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009755", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" } ], "pmid": "" }, { "name": "digestion", "id": "GO:0007586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007586", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" } ], "pmid": "" }, { "name": "cellular response to nutrient levels", "id": "GO:0031669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031669", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T2V1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T2V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T2V1" }, { "id": "PF00473", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00473" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Corticotropin-releasing factor", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 109, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T3G5-1", "uniprot_ac": "A0A4X1T3G5", "uniprot_id": "A0A4X1T3G5_PIG", "mass": { "chemical_mass": 103173.0, "monoisotopic_mass": 103173.0 }, "refseq": {}, "gene_names": [ { "name": "NRXN3", "type": "recommended", "evidence": [ { "id": "A0A4X1T3G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ] } ], "protein_names": [ { "name": "Neurexin 3", "type": "synonym", "evidence": [ { "id": "A0A4X1T3G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NRXN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5", "locus": { "chromosome": "7", "start_pos": 101938298, "end_pos": 101604569, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000028942", "url": "https://www.ensembl.org/id/ENSSSCG00000028942" } ] } } ], "crossref": [ { "id": "A0A4X1T3G5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T3G5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6794361", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6794361", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T3G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0YIL4", "url": "https://www.uniprot.org/uniprotkb/A0A8D0YIL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0YIL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0YIL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSFFSYDLPHKTSPFILNTPRFKGGKENISFAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIGDTKMKIYGEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKVIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSADGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDRKYNLFILGTFPEFSFFKVQSFRESLKVIMYKDGSAERFISSVLIQKLGK", "length": 925, "header": "tr|A0A4X1T3G5-1|A0A4X1T3G5_PIG Isoform 1 of Neurexin 3 OS=Sus scrofa OX=9823 GN=NRXN3 PE=1 SV=1 CANONICAL=A0A4X1T3G5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T3G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5/entry#A0A4X1T3G5-1", "sequence": { "sequence": "MMSFFSYDLPHKTSPFILNTPRFKGGKENISFAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIGDTKMKIYGEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKVIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSADGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDRKYNLFILGTFPEFSFFKVQSFRESLKVIMYKDGSAERFISSVLIQKLGK", "length": 925, "header": "tr|A0A4X1T3G5-1|A0A4X1T3G5_PIG Isoform 1 of Neurexin 3 OS=Sus scrofa OX=9823 GN=NRXN3 PE=1 SV=1 CANONICAL=A0A4X1T3G5-1" }, "locus": { "chromosome": "7", "start_pos": 101938295, "end_pos": 101604569, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037603.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037603.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036795.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036795.1" } ] } }, { "isoform_ac": "A0A8D0YIL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5/entry#A0A8D0YIL4-1", "sequence": { "sequence": "MQANVDCFPLPFPAAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIGDTKMKIYGEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKVIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSADGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEVALTKADLQGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDRKYNLFILGTFPEFSFFKVQSFRESLKVIMYKDGSAERFISSVLIQKLGK", "length": 916, "header": "tr|A0A8D0YIL4-1|A0A4X1T3G5_PIG Computationally mapped isoform of Neurexin 3 OS=Sus scrofa OX=9823 GN=NRXN3 PE=1 SV=1 CANONICAL=A0A4X1T3G5-1" }, "locus": { "chromosome": "7", "start_pos": 101938295, "end_pos": 101607329, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025256.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025256.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026569.3", "url": "https://www.ensembl.org/id/ENSSSCP00000026569.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0YIL4", "url": "https://www.uniprot.org/uniprotkb/A0A8D0YIL4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6794361", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6794361", "resource": "Reactome", "description": "Neurexins and neuroligins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "presynaptic active zone membrane", "id": "GO:0048787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048787", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "trans-synaptic protein complex", "id": "GO:0098820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098820", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "gephyrin clustering involved in postsynaptic density assembly", "id": "GO:0097116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097116", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "learning", "id": "GO:0007612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007612", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "adult behavior", "id": "GO:0030534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030534", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission", "id": "GO:0099557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099557", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "presynaptic modulation of chemical synaptic transmission", "id": "GO:0099171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099171", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0099645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099645", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "neuroligin family protein binding", "id": "GO:0097109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097109", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" }, { "name": "signaling receptor regulator activity", "id": "GO:0030545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030545", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T3G5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T3G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 431, "end_pos": 468, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T3G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T3G5" }, { "id": "PS50025", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50025" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin G", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 228, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 29, "end_pos": 31 }, { "start_pos": 545, "end_pos": 547 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T414-1", "uniprot_ac": "A0A4X1T414", "uniprot_id": "A0A4X1T414_PIG", "mass": { "chemical_mass": 98568.0, "monoisotopic_mass": 98568.0 }, "refseq": { "ac": "XP_020956470", "name": "rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020956470" }, "gene_names": [ { "name": "PDE6B", "type": "recommended", "evidence": [ { "id": "A0A4X1T414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ] }, { "name": "PDE6B", "type": "synonym", "evidence": [ { "id": "XP_020956470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020956470" } ] } ], "protein_names": [ { "name": "Phosphodiesterase", "type": "recommended", "evidence": [ { "id": "A0A4X1T414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414/entry#names_and_taxonomy" } ] }, { "name": "3.1.4.-", "type": "synonym", "evidence": [ { "id": "A0A4X1T414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414/entry#names_and_taxonomy" } ] }, { "name": "rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta", "type": "synonym", "evidence": [ { "id": "XP_020956470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020956470" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PDE6B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414", "locus": { "chromosome": "8", "start_pos": 110672, "end_pos": 80378, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036645", "url": "https://www.ensembl.org/id/ENSSSCG00000036645" } ] } } ], "crossref": [ { "id": "A0A4X1T414", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T414", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00077", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00077", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100625223", "url": "https://www.ncbi.nlm.nih.gov/gene/100625223", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100625223", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625223", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "REVYDCE", "url": "https://omabrowser.org/oma/group/REVYDCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T414", "url": "https://www.orthodb.org/?gene=A0A4X1T414", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00233", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00233", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01590", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01590", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2485179", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2485179", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2514859", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2514859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4086398", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4086398", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020956470", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020956470", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T414-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLNEEQVQEFLDQNPSFTDQYFGKKLSPENVASACEDRCPEGGASFRELCQVEESAALFELVQDMQESVNMERVVFKLLRRLCSILQADRCSLFMYRQRNGTAELATRLFSVQPDSVLEDCLVPADSEIVFPLDIGVVGHVAQTKKTVNVEDVRECPHFSSFADELTDYVTRNLLATPVMNGKDVVAVIMAVNKLNGPCFTSEDEDVFLKYLNFGTLNLKIYHLNYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMTKEKEFFDVWPVLMGEAQPYSGPRTPDGREILFYKVIDYILHGKEDIKVIPSPPADHWALASGLPTYVAESGFICNIMNAPADEMFKFQDGPLDDSGWTIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVLNTDTYDRMNKLENRKDIAQDMVLYHVKCDKDEIQSILPTRERFGKEPADCEEDELGKLLKEVLPGPTKFDIYEFHFSDLECTELELVKCGIQMYYELGVVRKFQIPQEVLVRFLFSVSKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRTMFQKIVDESKNYEDRKSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEDEQQKEEAQTAAKKAGTEVCNGGPAPKSSTCCIL", "length": 856, "header": "tr|A0A4X1T414-1|A0A4X1T414_PIG Isoform 1 of Phosphodiesterase OS=Sus scrofa OX=9823 GN=PDE6B PE=1 SV=1 CANONICAL=A0A4X1T414-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T414-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414/entry#A0A4X1T414-1", "sequence": { "sequence": "MSLNEEQVQEFLDQNPSFTDQYFGKKLSPENVASACEDRCPEGGASFRELCQVEESAALFELVQDMQESVNMERVVFKLLRRLCSILQADRCSLFMYRQRNGTAELATRLFSVQPDSVLEDCLVPADSEIVFPLDIGVVGHVAQTKKTVNVEDVRECPHFSSFADELTDYVTRNLLATPVMNGKDVVAVIMAVNKLNGPCFTSEDEDVFLKYLNFGTLNLKIYHLNYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMTKEKEFFDVWPVLMGEAQPYSGPRTPDGREILFYKVIDYILHGKEDIKVIPSPPADHWALASGLPTYVAESGFICNIMNAPADEMFKFQDGPLDDSGWTIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVLNTDTYDRMNKLENRKDIAQDMVLYHVKCDKDEIQSILPTRERFGKEPADCEEDELGKLLKEVLPGPTKFDIYEFHFSDLECTELELVKCGIQMYYELGVVRKFQIPQEVLVRFLFSVSKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRTMFQKIVDESKNYEDRKSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEDEQQKEEAQTAAKKAGTEVCNGGPAPKSSTCCIL", "length": 856, "header": "tr|A0A4X1T414-1|A0A4X1T414_PIG Isoform 1 of Phosphodiesterase OS=Sus scrofa OX=9823 GN=PDE6B PE=1 SV=1 CANONICAL=A0A4X1T414-1" }, "locus": { "chromosome": "8", "start_pos": 110366, "end_pos": 80378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053842.2", "url": "https://www.ensembl.org/id/ENSSSCT00000053842.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047634.1", "url": "https://www.ensembl.org/id/ENSSSCP00000047634.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100625223", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625223", "resource": "KEGG Pathway" }, { "id": "R-SSC-2485179", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2485179", "resource": "Reactome", "description": "Activation of the phototransduction cascade" }, { "id": "R-SSC-2514859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2514859", "resource": "Reactome", "description": "Inactivation, recovery and regulation of the phototransduction cascade" }, { "id": "R-SSC-4086398", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4086398", "resource": "Reactome", "description": "Ca2+ pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AC58IAR7-1", "protein_name": "Phosphodiesterase", "gene_name": "pde6b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVKKEDVEKFLDGNPDFTKTYFDKKLKPGAVASIMRVPESKVDMDSFKEIVSVEEGAIFYDLITDMQENVNMEKVIFKILKRISALIHADRCSLFMYRQRNGIAELATRLFNVNKDSELDDCVVAPDSEIVFPLDIGIVGHVAQTKKQVNVKDVTQDSHFSTFVDELTEYTTHNLLAAPIMNGKDVVAVIMAVNKTTGPHFTDEDMDLFLKYLKVGSLNLKIFHLSYLHNCETRKGQLLLWSANKVFEELTDIERQFHKALYTVRAYLNCDRYSVGLLDMTKEKEFFDIWPVLMGEQPPYSGPVTPDGREIIFYKVIDYILHGKEDIKVIPNPTADHWALASGLPTYVAESGFICNIMNAASEEMFKFQTEALDDSGWTIKNVLSLPIVNKKEEIVGVATFYNRKDGKPFDEHDEQLMEALTQFLGWSALNTDTYDKMNKLENRKDIAQDMVLYHVKCRDDEIQDILKTREYFDREPRDCEEEELLEILKKELPGPKKFEIYAFHFSDFDCTELQLVMCGIQMYYEVGVVKKFQVPQEVLVRFMYSVSKGYRRITYHNWRHGFNVGQTMFTLLTTGKLKQYYTDLEVMAMITAGFLHDIDHRGTNNLYQVKSQNPLAKLHGSSILERHHLEFGKFLLGEESLNIFQNLNRRQTEHVFHLIDIAIIATDLALYFKKRTMFQKIVDLSETYEERKKWIDFMSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALSVAAEFWEQGDLERTVLEQQPIPMMDRNKAAELPKLQCGFIDFVCTFVYKEFSRFHPEIKPMFDGILNNRMHWKERQEEYEAKLKAMEEAVKARQEAAAKNGLNNMSRLLNIHCICTRLDIRHTEKTYNVVILLINHGLCHCDQVWTPLQSAIYMLSIEISFESFLIVYYVIFNNNA", "length": 912 }, "evidence": [ { "id": "A0A4X1T414", "url": "https://omabrowser.org/oma/group/A0A4X1T414/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZDI8-1", "protein_name": "Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta", "gene_name": "Pde6b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSEEQVRSFLDGNPTFAHQYFEKKLSPENVAGACEGGCLVDCGSLRELCQVEESAALFELVQDMQESVNMERVVFKVLRRLCTILHADRCSLFMYRQRNGVAELATRLFSVQPDSLLEDCLVPPDSEIVFPLDIGIVGHVAQTKKMINVQDVAECPHFSPFADELTDYVTKNILSTPIMNGKDVVAVIMAVNKLDGPCFTSEDEDVFTKYLNFATLNLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMTKEKEFFDVWPVLMGEAQPYSGPRTPDGREIVFYKVIDYILHGKEDIKVIPTPPADHWALTSGLPTYVAESGFICNIMNASADEMFNFQEGPLDESGWVIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDDQDEVLMESLTQFLGWSVLNTDTYDKMNKLENRKDIAQDMVLYHVRCDKDEIQEILPTRDRLGKEPADCEEDELGKILKEELPGPTKFDIYEFHFSDLECTELELVKCGIQMYYELGVVRKFQIPQEVLVRFLFSVSKAYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLAEESLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRTMFQKIVDESKNYEDKKSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEEEKKKEEDRVAAKKAGTEICNGGPAPKSSTCCIL", "length": 856 }, "evidence": [ { "id": "A0A4X1T414", "url": "https://omabrowser.org/oma/group/A0A4X1T414/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N0U0-1", "protein_name": "Phosphodiesterase", "gene_name": "PDE6B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLSEGQVHRFLDQNPGFADQYFGRKLSPEDVANACEDGCPEGCTSFRELCQVEESAALFELVQDMQENVNMERVVFKILRRLCSILHADRCSLFMYRQRNGVAELATRLFSVQPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVQDVMECPHFSSFADELTDYVTRNILATPIMNGKDVVAVIMAVNKLDGPCFTSEDEDVFLKYLNFGTLNLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMTKEKEFFDVWPVLMGEAQAYSGPRTPDGREILFYKVIDYILHGKEDIKVIPSPPADHWALASGLPTYVAESGFICNIMNAPADEMFNFQEGPLDDSGWIVKNVLSMPIVNKKEIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVLNTDTYDKMNKLENRKDIAQDMVLYHVRCDREEIQLILPTRERLGKEPADCEEDELGKILKEVLPGPAKFDIYEFHFSDLECTELELVKCGIQMYYELGVVRKFQIPQEVLVRFLFSVSKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRTMFQKIVDESKNYEDRKSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEEDQKKETTAKKVGTEICNGGPAPRSSTCRIL", "length": 852 }, "evidence": [ { "id": "A0A4X1T414", "url": "https://omabrowser.org/oma/group/A0A4X1T414/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P23440-1", "protein_name": "Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta", "gene_name": "Pde6b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLSEEQVRSFLDGNPTFAHQYFGKKLSPENVAGACEDGWLADCGSLRELCQVEESAALFELVQDMQESVNMERVVFKILRRLCTILHADRCSLFMYRQRNGIAELATRLFSVQPDSLLEDCLVPPDSEIVFPLDIGIVGHVAQTKKMINVQDVAECPHFSSFADELTDYVTKNILSTPIMNGKDVVAVIMAVNKLDGPCFTSEDEDVFTKYLNFATLNLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCERYSVGLLDMTKEKEFFDVWPVLMGEAQPYSGPRTPDGREIVFYKVIDYILHGKEDIKVIPTPPADHWALASGLPTYVAESGFICNIMNASADEMFNFQEGPLDDSGWVIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDDQDEVLMESLTQFLGWSVLNTDTYDKMNKLENRKDIAQDMVLYHVRCDKDEIQEILPTRDRLGKEPADCEEDELGKILKEELPGPTKFDIYEFHFSDLECTELELVKCGIQMYYELGVVRKFQIPQEVLVRFLFSVSKAYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLAEESLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRTMFQKIVDESKNYEDKKSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEEEKKKEEDRVAAKKVGTEVCNGGPAPKSSTCCIL", "length": 856 }, "evidence": [ { "id": "A0A4X1T414", "url": "https://omabrowser.org/oma/group/A0A4X1T414/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35913-1", "protein_name": "Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta", "gene_name": "PDE6B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLSEEQARSFLDQNPDFARQYFGKKLSPENVAAACEDGCPPDCDSLRDLCQVEESTALLELVQDMQESINMERVVFKVLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSVQPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVEDVAECPHFSSFADELTDYKTKNMLATPIMNGKDVVAVIMAVNKLNGPFFTSEDEDVFLKYLNFATLYLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCERYSVGLLDMTKEKEFFDVWSVLMGESQPYSGPRTPDGREIVFYKVIDYVLHGKEEIKVIPTPSADHWALASGLPSYVAESGFICNIMNASADEMFKFQEGALDDSGWLIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVMNTDTYDKMNKLENRKDIAQDMVLYHVKCDRDEIQLILPTRARLGKEPADCDEDELGEILKEELPGPTTFDIYEFHFSDLECTELDLVKCGIQMYYELGVVRKFQIPQEVLVRFLFSISKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDKKSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEEKEEEERVAAKKVGTEICNGGPAPKSSTCCIL", "length": 854 }, "evidence": [ { "id": "A0A4X1T414", "url": "https://omabrowser.org/oma/group/A0A4X1T414/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ], "pmid": "" }, { "name": "entrainment of circadian clock by photoperiod", "id": "GO:0043153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043153", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ], "pmid": "" }, { "name": "negative regulation of cAMP/PKA signal transduction", "id": "GO:0141162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141162", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ], "pmid": "" }, { "name": "3',5'-cyclic-GMP phosphodiesterase activity", "id": "GO:0047555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047555", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ], "pmid": "" }, { "name": "3',5'-cyclic-AMP phosphodiesterase activity", "id": "GO:0004115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004115", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "photoreceptor disc membrane", "id": "GO:0097381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097381", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ], "pmid": "" }, { "name": "photoreceptor outer segment membrane", "id": "GO:0042622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042622", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T414", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-2584246", "name": "GNAT1-GTP hydrolyses its bound GTP to GDP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, photoreceptor disc membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2584246", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2584246" } ] }, { "id": "R-SSC-4086392", "name": "PDE6 hydrolyses cGMP to GMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-4086392", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4086392" } ] }, { "id": "R-SSC-74059", "name": "PDE6 hydrolyses cGMP to GMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, photoreceptor disc membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-74059", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-74059" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" }, { "id": "PS51845", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51845" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDEase", "eco_id": "ECO_0000259", "start_pos": 481, "end_pos": 814, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A4X1T414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414#function" }, { "id": "A0A4X1T414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" }, { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 561, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 561, "end_pos": 561, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414#function" }, { "id": "A0A4X1T414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" }, { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 597, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 597, "end_pos": 597, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414#function" }, { "id": "A0A4X1T414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" }, { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 598, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 598, "end_pos": 598, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414#function" }, { "id": "A0A4X1T414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T414" }, { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 718, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 718, "end_pos": 718, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T454-1", "uniprot_ac": "A0A4X1T454", "uniprot_id": "A0A4X1T454_PIG", "mass": { "chemical_mass": 16561.0, "monoisotopic_mass": 16561.0 }, "refseq": {}, "gene_names": [ { "name": "SLIRP", "type": "recommended", "evidence": [ { "id": "A0A4X1T454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ] } ], "protein_names": [ { "name": "SRA stem-loop-interacting RNA-binding protein, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A4X1T454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454#function" }, { "database": "UniProtKB", "id": "ARBA00057077", "url": "https://www.uniprot.org/uniprotkb/ARBA00057077#function" }, { "database": "UniProtKB", "id": "A0A4X1T4M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4M0#function" }, { "database": "UniProtKB", "id": "A0A8W4FL11", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FL11#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLIRP", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454", "locus": { "chromosome": "7", "start_pos": 100720374, "end_pos": 100710234, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000028167", "url": "https://www.ensembl.org/id/ENSSSCG00000028167" } ] } } ], "crossref": [ { "id": "A0A4X1T454", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T454", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12242", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12242", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11176:SF61", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11176:SF61", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T454-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T4M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T4M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FL11", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FL11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FL11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FL11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRPVSSDPEADFRAPGSDRFFRGRDLKALGSLNLNMAASAARGVLSMRANVGRPVAFVRKIPWTAASNELREHFAQFGHIRKCIVPFDKETGFHRGMGWIQFSSEEELHNVLQQENHVIDGVKLHVQAQKRKALQGDQTSDEEKDF", "length": 147, "header": "tr|A0A4X1T454-1|A0A4X1T454_PIG Isoform 1 of SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Sus scrofa OX=9823 GN=SLIRP PE=1 SV=1 CANONICAL=A0A4X1T454-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T454-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454/entry#A0A4X1T454-1", "sequence": { "sequence": "MSRPVSSDPEADFRAPGSDRFFRGRDLKALGSLNLNMAASAARGVLSMRANVGRPVAFVRKIPWTAASNELREHFAQFGHIRKCIVPFDKETGFHRGMGWIQFSSEEELHNVLQQENHVIDGVKLHVQAQKRKALQGDQTSDEEKDF", "length": 147, "header": "tr|A0A4X1T454-1|A0A4X1T454_PIG Isoform 1 of SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Sus scrofa OX=9823 GN=SLIRP PE=1 SV=1 CANONICAL=A0A4X1T454-1" }, "locus": { "chromosome": "7", "start_pos": 100718261, "end_pos": 100710381, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074219.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074219.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066201.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066201.1" } ] } }, { "isoform_ac": "A0A4X1T4M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454/entry#A0A4X1T4M0-1", "sequence": { "sequence": "MAASAARGVLSMRANVGRPVAFVRKIPWTAASNELREHFAQFGHIRKCIVPFDKETGFHRGMGWIQFSSEEELHNVLQQENHVIDGVKCLKSWLILRGQ", "length": 99, "header": "tr|A0A4X1T4M0-1|A0A4X1T4M0_PIG Computationally mapped isoform of SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Sus scrofa OX=9823 GN=SLIRP PE=1 SV=1 CANONICAL=A0A4X1T454-1" }, "locus": { "chromosome": "7", "start_pos": 100720374, "end_pos": 100710489, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031620.4", "url": "https://www.ensembl.org/id/ENSSSCT00000031620.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024715.3", "url": "https://www.ensembl.org/id/ENSSSCP00000024715.3" } ] } }, { "isoform_ac": "A0A8W4FL11-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454/entry#A0A8W4FL11-1", "sequence": { "sequence": "MAASAARGVLSMRANVGRPVAFVRKIPWTAASNELREHFAQFGHIRKCIVPFDKETGFHRGMGWIQFSSEEELHNVLQQENHVIDGVKVMELKSWLFYLLCDLGPK", "length": 106, "header": "tr|A0A8W4FL11-1|A0A4X1T454_PIG Computationally mapped isoform of SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Sus scrofa OX=9823 GN=SLIRP PE=1 SV=1 CANONICAL=A0A4X1T454-1" }, "locus": { "chromosome": "7", "start_pos": 100718030, "end_pos": 100710489, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104739.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104739.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079598.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079598.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FL11", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FL11" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "pmid": "" }, { "name": "mitochondrial mRNA polyadenylation", "id": "GO:0097222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097222", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial mRNA catabolic process", "id": "GO:1905638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905638", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T454", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T454" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 132, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T475-1", "uniprot_ac": "A0A4X1T475", "uniprot_id": "A0A4X1T475_PIG", "mass": { "chemical_mass": 29507.0, "monoisotopic_mass": 29507.0 }, "refseq": {}, "gene_names": [ { "name": "NNMT", "type": "recommended", "evidence": [ { "id": "A0A4X1T475", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475" } ] } ], "protein_names": [ { "name": "Nicotinamide N-methyltransferase", "type": "synonym", "evidence": [ { "id": "A0A4X1T475", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T475", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NNMT", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475", "locus": { "chromosome": "9", "start_pos": 41882756, "end_pos": 41870980, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015054", "url": "https://www.ensembl.org/id/ENSSSCG00000015054" } ] } } ], "crossref": [ { "id": "A0A4X1T475", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T475", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CMYTAMA", "url": "https://omabrowser.org/oma/group/CMYTAMA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10867", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10867", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10867:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10867:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156581", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156581", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-196807", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-196807", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T475", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T475-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESGFTSKDAYLSHFNPQDYLEKYYNFGAKHSAEDQILRHLLKILFKIFCLDGVKGDLLIDIGSGPTIYQLLSACESFKEIIATDYTDQNLQELEKWLKKEPGAFDWSPVVTYVCELEGNRVKGTEKEEKLRRAVKRVLKCDVTQSWPLGAVPLPPADCLLSTLCLHAACPDLPTYRTALGNLRSLLKPGGFLVLVDALKSSYYMIGEQRFSSLCLGREAVEAAVREAGYTIEHFEVISQSYSSTMANNEGLFSLVGRKLSPCV", "length": 264, "header": "tr|A0A4X1T475-1|A0A4X1T475_PIG Isoform 1 of Nicotinamide N-methyltransferase OS=Sus scrofa OX=9823 GN=NNMT PE=3 SV=1 CANONICAL=A0A4X1T475-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T475-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475/entry#A0A4X1T475-1", "sequence": { "sequence": "MESGFTSKDAYLSHFNPQDYLEKYYNFGAKHSAEDQILRHLLKILFKIFCLDGVKGDLLIDIGSGPTIYQLLSACESFKEIIATDYTDQNLQELEKWLKKEPGAFDWSPVVTYVCELEGNRVKGTEKEEKLRRAVKRVLKCDVTQSWPLGAVPLPPADCLLSTLCLHAACPDLPTYRTALGNLRSLLKPGGFLVLVDALKSSYYMIGEQRFSSLCLGREAVEAAVREAGYTIEHFEVISQSYSSTMANNEGLFSLVGRKLSPCV", "length": 264, "header": "tr|A0A4X1T475-1|A0A4X1T475_PIG Isoform 1 of Nicotinamide N-methyltransferase OS=Sus scrofa OX=9823 GN=NNMT PE=3 SV=1 CANONICAL=A0A4X1T475-1" }, "locus": { "chromosome": "9", "start_pos": 41882412, "end_pos": 41871072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016420.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016420.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015979.3", "url": "https://www.ensembl.org/id/ENSSSCP00000015979.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T475", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156581", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156581", "resource": "Reactome", "description": "Methylation" }, { "id": "R-SSC-196807", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-196807", "resource": "Reactome", "description": "Nicotinate metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QUL7-1", "protein_name": "2.1.1.1", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSECTNFTEGEFYQAHFDPRAYVRNFYSSPRGHSDEKDFLTFVLGVFSRLFSTGKHRGQRLIDVGSGPSIHCVISACAHYDEILLSDFSDNNRREIEKWLKNQEGCLDWSPILQHVSKTEGKRPSDLEATLKQRIKKVLKCDVRLENPFDPLTLEPADCVITSLCLEAACKDMQIYRQALHGLTKLLCPGGLFVMVGVLSETFYKVDEQLFSCLSLKQNDIEEALKGFGFSIQEFNVLPAEDQNNSVSDFEAVFVLVATKNI", "length": 262 }, "evidence": [ { "id": "A0A4X1T475", "url": "https://omabrowser.org/oma/group/A0A4X1T475/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P40261-1", "protein_name": "Nicotinamide N-methyltransferase", "gene_name": "NNMT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLIDIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGNRVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRALRNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQSYSSTMANNEGLFSLVARKLSRPL", "length": 264 }, "evidence": [ { "id": "A0A4X1T475", "url": "https://omabrowser.org/oma/group/A0A4X1T475/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nicotinamide N-methyltransferase activity", "id": "GO:0008112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008112", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T475", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "NAD+ catabolic process", "id": "GO:0019677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T475", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T475", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475" } ], "pmid": "" }, { "name": "positive regulation of gluconeogenesis", "id": "GO:0045722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045722", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T475", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475" } ], "pmid": "" }, { "name": "nicotinamide metabolic process", "id": "GO:0006769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006769", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T475", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T475", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T475" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T4C3-1", "uniprot_ac": "A0A4X1T4C3", "uniprot_id": "A0A4X1T4C3_PIG", "mass": { "chemical_mass": 19550.0, "monoisotopic_mass": 19550.0 }, "refseq": { "ac": "XP_005668017", "name": "desumoylating isopeptidase 2 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668017" }, "gene_names": [ { "name": "DESI2", "type": "recommended", "evidence": [ { "id": "A0A4X1T4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3" } ] }, { "name": "CGI-146", "type": "synonym", "evidence": [ { "id": "XP_005668017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668017" } ] }, { "name": "DESI2", "type": "synonym", "evidence": [ { "id": "XP_005668017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668017" } ] }, { "name": "DeSI-2", "type": "synonym", "evidence": [ { "id": "XP_005668017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668017" } ] }, { "name": "FAM152A", "type": "synonym", "evidence": [ { "id": "XP_005668017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668017" } ] }, { "name": "PNAS-4", "type": "synonym", "evidence": [ { "id": "XP_005668017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668017" } ] }, { "name": "PPPDE1", "type": "synonym", "evidence": [ { "id": "XP_005668017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668017" } ] } ], "protein_names": [ { "name": "Deubiquitinase DESI2", "type": "recommended", "evidence": [ { "id": "A0A4X1T4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3/entry#names_and_taxonomy" } ] }, { "name": "3.1.2.22", "type": "synonym", "evidence": [ { "id": "A0A4X1T4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "A0A4X1T4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3/entry#names_and_taxonomy" } ] }, { "name": "Desumoylating isopeptidase 2", "type": "synonym", "evidence": [ { "id": "A0A4X1T4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3/entry#names_and_taxonomy" } ] }, { "name": "PPPDE peptidase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A4X1T4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3/entry#names_and_taxonomy" } ] }, { "name": "Palmitoyl protein thioesterase DESI2", "type": "synonym", "evidence": [ { "id": "A0A4X1T4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3/entry#names_and_taxonomy" } ] }, { "name": "Protein FAM152A", "type": "synonym", "evidence": [ { "id": "A0A4X1T4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3/entry#names_and_taxonomy" } ] }, { "name": "S-depalmitoylase DESI2", "type": "synonym", "evidence": [ { "id": "A0A4X1T4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3/entry#names_and_taxonomy" } ] }, { "name": "desumoylating isopeptidase 2 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_005668017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668017" } ] } ], "function": [ { "annotation": "Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity towards synthetic substrates 4-methylumbelliferyl-6-S-palmitoyl-beta-D-glucopyranoside and S-depalmitoylation probe 5 (DPP-5).", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4C3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3#function" }, { "database": "UniProtKB", "id": "ARBA00045915", "url": "https://www.uniprot.org/uniprotkb/ARBA00045915#function" }, { "database": "UniProtKB", "id": "A0A5G2QUA3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4C3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DESI2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3", "locus": { "chromosome": "10", "start_pos": 17416635, "end_pos": 17365689, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010876", "url": "https://www.ensembl.org/id/ENSSSCG00000010876" } ] } } ], "crossref": [ { "id": "A0A4X1T4C3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T4C3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010876", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010876", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100037270", "url": "https://www.ncbi.nlm.nih.gov/gene/100037270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008580", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008580", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T4C3", "url": "https://www.orthodb.org/?gene=A0A4X1T4C3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12378", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12378", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12378:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12378:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005668017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668017", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19233", "url": "https://www.rhea-db.org/rhea/19233", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T4C3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T4C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUA3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEYTSSIGIGVFHSGIEVYGREFAYGGHPYPFSGIFEISPGNASELGETFKFKEAVVLGSTDFLEDDIEKIVEELGKEYKGNAYHLMHKNCNHFSSALSEILCGKEIPRWINRLAYFSSCIPFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAASASMGSASAGSRPGRHTKL", "length": 178, "header": "tr|A0A4X1T4C3-1|A0A4X1T4C3_PIG Isoform 1 of Deubiquitinase DESI2 OS=Sus scrofa OX=9823 GN=DESI2 PE=3 SV=1 CANONICAL=A0A4X1T4C3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T4C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3/entry#A0A4X1T4C3-1", "sequence": { "sequence": "MNEYTSSIGIGVFHSGIEVYGREFAYGGHPYPFSGIFEISPGNASELGETFKFKEAVVLGSTDFLEDDIEKIVEELGKEYKGNAYHLMHKNCNHFSSALSEILCGKEIPRWINRLAYFSSCIPFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAASASMGSASAGSRPGRHTKL", "length": 178, "header": "tr|A0A4X1T4C3-1|A0A4X1T4C3_PIG Isoform 1 of Deubiquitinase DESI2 OS=Sus scrofa OX=9823 GN=DESI2 PE=3 SV=1 CANONICAL=A0A4X1T4C3-1" }, "locus": { "chromosome": "10", "start_pos": 17413361, "end_pos": 17396903, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011898.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011898.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011594.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011594.4" } ] } }, { "isoform_ac": "A0A5G2QUA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3/entry#A0A5G2QUA3-1", "sequence": { "sequence": "MGANQLVVLNVYDMYWMNEYTSSIGIGVFHSGIEVYGREFAYGGHPYPFSGIFEISPGNASELGETFKFKEAVVLGSTDFLEDDIEKIVEELGKEYKGNAYHLMHKNCNHFSSALSEMIHRTTKVGDVVTNQSFGCMSTMEGTELIEGRGKAVLSFLGLDVTFVGNVFRAQPVEG", "length": 175, "header": "tr|A0A5G2QUA3-1|A0A4X1T4C3_PIG Computationally mapped isoform of Deubiquitinase DESI2 OS=Sus scrofa OX=9823 GN=DESI2 PE=3 SV=1 CANONICAL=A0A4X1T4C3-1" }, "locus": { "chromosome": "10", "start_pos": 17403400, "end_pos": 17365904, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068944.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068944.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068516.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068516.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUA3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4C3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4C3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "palmitoyl-(protein) hydrolase activity", "id": "GO:0008474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008474", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4C3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4C3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3" } ], "pmid": "" }, { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4C3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3" } ], "pmid": "" }, { "name": "K48-linked deubiquitinase activity", "id": "GO:1990380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990380", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4C3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3" } ], "pmid": "" }, { "name": "long-chain fatty acyl-CoA hydrolase activity", "id": "GO:0052816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052816", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4C3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3" } ], "pmid": "" }, { "name": "deubiquitinase activity", "id": "GO:0101005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0101005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4C3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19233", "name": "", "equation": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19233", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19233" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4C3" }, { "id": "PS51858", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51858" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPPDE", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 133, "start_aa": "Met", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T4J2-1", "uniprot_ac": "A0A4X1T4J2", "uniprot_id": "A0A4X1T4J2_PIG", "mass": { "chemical_mass": 78306.0, "monoisotopic_mass": 78306.0 }, "refseq": { "ac": "XP_003354913", "name": "ras guanyl-releasing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354913" }, "gene_names": [ { "name": "RASGRP3", "type": "recommended", "evidence": [ { "id": "A0A4X1T4J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ] }, { "name": "RASGRP3", "type": "synonym", "evidence": [ { "id": "XP_003354913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354913" } ] } ], "protein_names": [ { "name": "RAS guanyl releasing protein 3", "type": "synonym", "evidence": [ { "id": "A0A4X1T4J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2/entry#names_and_taxonomy" } ] }, { "name": "ras guanyl-releasing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003354913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354913" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RASGRP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2", "locus": { "chromosome": "3", "start_pos": 106099821, "end_pos": 106213728, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008509", "url": "https://www.ensembl.org/id/ENSSSCG00000008509" } ] } } ], "crossref": [ { "id": "A0A4X1T4J2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T4J2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008509", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008509", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20862", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20862", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100511446", "url": "https://www.ncbi.nlm.nih.gov/gene/100511446", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511446", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511446", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QNRVTHR", "url": "https://omabrowser.org/oma/group/QNRVTHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T4J2", "url": "https://www.orthodb.org/?gene=A0A4X1T4J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113:SF178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113:SF178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1169092", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1169092", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003354913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354913", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T4J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S407", "url": "https://www.uniprot.org/uniprotkb/F1S407", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S407-1", "url": "https://www.uniprot.org/uniprotkb/F1S407-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSGLGKAATLDELLSTCIEMFDDNGELNNSYLPRIVLLMHRWYLSSTELAGKLLCMYRNASGESCDEFRLKICYFMRYWILKFPAEFNLDLGLIHMTEEFREVASQLGYEKHVSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNLDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPTKPMVPLEWASGVLPKPDPTVINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFVHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARATSVGSSHGSLPGSPSLPPVQDEVFEFPGVAAGHRDLDSRAITLVTGSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKATKDKGFAKWENEKPRVQAGVDVVDRGTAFELDQEEADMGETRQDGEDG", "length": 692, "header": "tr|A0A4X1T4J2-1|A0A4X1T4J2_PIG Isoform 1 of RAS guanyl releasing protein 3 OS=Sus scrofa OX=9823 GN=RASGRP3 PE=3 SV=1 CANONICAL=A0A4X1T4J2-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T4J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2/entry#A0A4X1T4J2-1", "sequence": { "sequence": "MGSSGLGKAATLDELLSTCIEMFDDNGELNNSYLPRIVLLMHRWYLSSTELAGKLLCMYRNASGESCDEFRLKICYFMRYWILKFPAEFNLDLGLIHMTEEFREVASQLGYEKHVSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNLDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPTKPMVPLEWASGVLPKPDPTVINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFVHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARATSVGSSHGSLPGSPSLPPVQDEVFEFPGVAAGHRDLDSRAITLVTGSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKATKDKGFAKWENEKPRVQAGVDVVDRGTAFELDQEEADMGETRQDGEDG", "length": 692, "header": "tr|A0A4X1T4J2-1|A0A4X1T4J2_PIG Isoform 1 of RAS guanyl releasing protein 3 OS=Sus scrofa OX=9823 GN=RASGRP3 PE=3 SV=1 CANONICAL=A0A4X1T4J2-1" }, "locus": { "chromosome": "3", "start_pos": 106139917, "end_pos": 106101606, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051583.2", "url": "https://www.ensembl.org/id/ENSSSCT00000051583.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052091.1", "url": "https://www.ensembl.org/id/ENSSSCP00000052091.1" } ] } }, { "isoform_ac": "F1S407-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2/entry#F1S407-1", "sequence": { "sequence": "MRPIDDNGELNNSYLPRIVLLMHRWYLSSTELAGKLLCMYRNASGESCDEFRLKICYFMRYWILKFPAEFNLDLGLIHMTEEFREVASQLGYEKHVSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNLDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPTKPMVPLEWASGVLPKPDPTVINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFVHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARATSVGSSHGSLPGSPSLPPVQDEVFEFPGVAAGHRDLDSRAITLVTGSSRKISVRLQRDSGSHTFPKMKSKFHDKATKDKGFAKWENEKPRVQAGVDVVDRGTAFELDQEEADMGETRQDGEDG", "length": 654, "header": "tr|F1S407-1|A0A4X1T4J2_PIG Computationally mapped isoform of RAS guanyl releasing protein 3 OS=Sus scrofa OX=9823 GN=RASGRP3 PE=3 SV=4 CANONICAL=A0A4X1T4J2-1" }, "locus": { "chromosome": "3", "start_pos": 106144059, "end_pos": 106101606, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009311.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009311.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009073.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009073.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S407", "url": "https://www.uniprot.org/uniprotkb/F1S407" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511446", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511446", "resource": "KEGG Pathway" }, { "id": "R-SSC-1169092", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1169092", "resource": "Reactome", "description": "Activation of RAS in B cells" }, { "id": "R-SSC-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B4V9-1", "protein_name": "Ras guanyl-releasing protein 3 isoform X1", "gene_name": "rasgrp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSFTLGKAASLELLLDACIHAFDDKGELHENQLPRTFLLMHRWYVSSTELAGKLLIMYRDCRGDDCQRTRLKICYLMRYWIAEFPAEFDLDLGLIRLTEEFRDAAAELGGDKHIKLLDISTIPSYDWMRKLTQRKKQVKKGKASLLFDHLEPIELAEHLTFLEYKSIRRISFTDYQSYVIHGCLVDNPTLERSIALFNGISQWVQLMVLSKLTPQHRAEVITKYIHVAQKLLHLQNFNTLMAVVGGLSHSSISRLKETHSHLSPEVTKIWNEMTELVSSNGNYCAYRKAFGESKGFKIPILGVHLKDLIAVHVVFADWVEDGKVNITKMQQLFLTFNELVSLQSAVAQVEPNMDLIYLLNLSLDLYYTEDEIYELSLLREPRNPKSQPTSPTTPNKPLAPLDWASGVTTKPDPSVVNKHIRKVVDSVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRANPLLQCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGVNCHKQCRELLVLACRRLPRSTSLGSVSPGVLTHSSLPSSPNLPTCKDDDEVFTFPTVSPSSGSDLEGKSITLMTGSAQRISVRLQRATTSQATQTEEHLWPENGWAAVADSGSHTFPKMRYRPHRKASKSKGFARWENDTQGSMGTRNSRNSQEHSEESQQNGLTEQHTNKTRTSEIS", "length": 708 }, "evidence": [ { "id": "A0A4X1T4J2", "url": "https://omabrowser.org/oma/group/A0A4X1T4J2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F6QW76-1", "protein_name": "RAS guanyl releasing protein 3", "gene_name": "RASGRP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSGLGKAATLDELLSTCIEMFDDNGELNNSYLPRIVLLMHRWYLSSTELAEKLLCIYRNASGESCDEFRLKICYFMRYWIVKFPAEFNLDLGLIRMTEEFREVASQLGYEKHTSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMMELVSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNLDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPTKPVVPLEWASGVMPKPDPTVINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFVHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLGSSHGSLPGSPSLPPVQDEVFEFPGVTAGHRDLDSRAITLVTGSSGKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMRSKFHDKAAKDKGFAKWENEKPRVQAGVDVVDRGTTFEPDQDEADMDETKQDGEDG", "length": 692 }, "evidence": [ { "id": "A0A4X1T4J2", "url": "https://omabrowser.org/oma/group/A0A4X1T4J2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8IV61-1", "protein_name": "Ras guanyl-releasing protein 3", "gene_name": "RASGRP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYRNATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPTVINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQDGEDG", "length": 690 }, "evidence": [ { "id": "A0A4X1T4J2", "url": "https://omabrowser.org/oma/group/A0A4X1T4J2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor complex", "id": "GO:0032045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032045", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4J2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T4J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 420, "end_pos": 455, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T4J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" }, { "id": "PS50212", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50212" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-terminal Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 125, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T4J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" }, { "id": "PS50081", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phorbol-ester/DAG-type", "eco_id": "ECO_0000259", "start_pos": 494, "end_pos": 544, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T4J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4J2" }, { "id": "PS50009", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50009" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 152, "end_pos": 383, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T4S6-1", "uniprot_ac": "A0A4X1T4S6", "uniprot_id": "A0A4X1T4S6_PIG", "mass": { "chemical_mass": 38273.0, "monoisotopic_mass": 38273.0 }, "refseq": { "ac": "XP_001929185", "name": "eukaryotic translation initiation factor 2 subunit 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929185" }, "gene_names": [ { "name": "EIF2S2", "type": "recommended", "evidence": [ { "id": "A0A4X1T4S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6" } ] }, { "name": "EIF2S2", "type": "synonym", "evidence": [ { "id": "XP_001929185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929185" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 2 subunit 2", "type": "recommended", "evidence": [ { "id": "A0A4X1T4S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6/entry#names_and_taxonomy" } ] }, { "name": "Eukaryotic translation initiation factor 2 subunit beta", "type": "synonym", "evidence": [ { "id": "A0A4X1T4S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6/entry#names_and_taxonomy" } ] }, { "name": "eukaryotic translation initiation factor 2 subunit 2", "type": "synonym", "evidence": [ { "id": "XP_001929185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929185" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4S6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EIF2S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6", "locus": { "chromosome": "17", "start_pos": 37538321, "end_pos": 37570224, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026617", "url": "https://www.ensembl.org/id/ENSSSCG00000026617" } ] } } ], "crossref": [ { "id": "A0A4X1T4S6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T4S6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100621044", "url": "https://www.ncbi.nlm.nih.gov/gene/100621044", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016189", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016189", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045196", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045196", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621044", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621044", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CMREGNK", "url": "https://omabrowser.org/oma/group/CMREGNK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T4S6", "url": "https://www.orthodb.org/?gene=A0A4X1T4S6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23001:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23001:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-381042", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-381042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72731", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72731", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9840373", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840373", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001929185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929185", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T4S6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T4S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGDEMIFDPTMSKKKKKKKKPFMLDEEGDAQTEETQPSETKEVEPEPTEDKDVEADEEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIESDVQEPAEPEDDLDIMLGNKKKKKKNVKFPDEDEILEKDEALEDEDSKKDDGISFSNQTGPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN", "length": 333, "header": "tr|A0A4X1T4S6-1|A0A4X1T4S6_PIG Isoform 1 of Eukaryotic translation initiation factor 2 subunit 2 OS=Sus scrofa OX=9823 GN=EIF2S2 PE=1 SV=1 CANONICAL=A0A4X1T4S6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T4S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6/entry#A0A4X1T4S6-1", "sequence": { "sequence": "MSGDEMIFDPTMSKKKKKKKKPFMLDEEGDAQTEETQPSETKEVEPEPTEDKDVEADEEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIESDVQEPAEPEDDLDIMLGNKKKKKKNVKFPDEDEILEKDEALEDEDSKKDDGISFSNQTGPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN", "length": 333, "header": "tr|A0A4X1T4S6-1|A0A4X1T4S6_PIG Isoform 1 of Eukaryotic translation initiation factor 2 subunit 2 OS=Sus scrofa OX=9823 GN=EIF2S2 PE=1 SV=1 CANONICAL=A0A4X1T4S6-1" }, "locus": { "chromosome": "17", "start_pos": 37570108, "end_pos": 37551490, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029372.4", "url": "https://www.ensembl.org/id/ENSSSCT00000029372.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019782.2", "url": "https://www.ensembl.org/id/ENSSSCP00000019782.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4S6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621044", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621044", "resource": "KEGG Pathway" }, { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-381042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-381042", "resource": "Reactome", "description": "PERK regulates gene expression" }, { "id": "R-SSC-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-SSC-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-SSC-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-SSC-72731", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72731", "resource": "Reactome", "description": "Recycling of eIF2:GDP" }, { "id": "R-SSC-9840373", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840373", "resource": "Reactome", "description": "Cellular response to mitochondrial stress" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HAN5-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 2", "gene_name": "Eif2s2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGDEMIFDPTMSKKKKKKKKPFMLDEEGDAQTEETQPSETKEVEPEPTEDKDVEADEEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIESDAPEPAEPEDDLDIMLGNKKKKKKNVKFPDEDEILEKDEALEDEDSKKDDGISFSNQTGPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN", "length": 333 }, "evidence": [ { "id": "A0A4X1T4S6", "url": "https://omabrowser.org/oma/group/A0A4X1T4S6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P09064-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit beta", "gene_name": "SUI3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSDLAAELGFDPALKKKKKTKKVIPDDFDAAVNGKENGSGDDLFAGLKKKKKKSKSVSADAEAEKEPTDDIAEALGELSLKKKKKKTKDSSVDAFEKELAKAGLDNVDAESKEGTPSANSSIQQEVGLPYSELLSRFFNILRTNNPELAGDRSGPKFRIPPPVCLRDGKKTIFSNIQDIAEKLHRSPEHLIQYLFAELGTSGSVDGQKRLVIKGKFQSKQMENVLRRYILEYVTCKTCKSINTELKREQSNRLFFMVCKSCGSTRSVSSIKTGFQATVGKRRRM", "length": 285 }, "evidence": [ { "id": "A0A4X1T4S6", "url": "https://omabrowser.org/oma/group/A0A4X1T4S6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P20042-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 2", "gene_name": "EIF2S2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGDEMIFDPTMSKKKKKKKKPFMLDEEGDTQTEETQPSETKEVEPEPTEDKDLEADEEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIESDVQEPTEPEDDLDIMLGNKKKKKKNVKFPDEDEILEKDEALEDEDNKKDDGISFSNQTGPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN", "length": 333 }, "evidence": [ { "id": "A0A4X1T4S6", "url": "https://omabrowser.org/oma/group/A0A4X1T4S6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54T27-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 2", "gene_name": "eif2s2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSATEEENVLVFDTTMKKKKKSKDSAAQTEEEKKKLKSKTLAMMSQQEDEQEQEDEKKEKRKKKKAALLASTEGENSEAIEKLENEGAHDEDIEAEFMGEKKKKKKSSKSSTTTTTSTTTTTTEPTETEPTEDGESKEKTITTSDGDTFVQGTIPWAGTDRDYKYSELTYRIYHLLQANNPDLISDQKRTMKPPQVMREGTKKTIWANFAEICGTLNRKVEHVYNYVFAELGTNGSIDGNQRLVIRGRFKTSQIEIVIRHYISEYVACRNCKSPNTVLERNNRLYFLCCNACNSKRSVAVIKKGLEGAGKKAPKEQS", "length": 317 }, "evidence": [ { "id": "A0A4X1T4S6", "url": "https://omabrowser.org/oma/group/A0A4X1T4S6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q99L45-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 2", "gene_name": "Eif2s2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGDEMIFDPTMSKKKKKKKKPFMLDEEGDAQTEETQPSETKEVEPEPTEEKDVDADEEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEAIKDVKIESDAQEPAEPEDDLDIMLGNKKKKKKNVKFPEEDEILEKDEALEDEDSKKDDGISFSSQTAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN", "length": 331 }, "evidence": [ { "id": "A0A4X1T4S6", "url": "https://omabrowser.org/oma/group/A0A4X1T4S6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4S6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4S6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6" } ], "pmid": "" }, { "name": "translation initiation factor binding", "id": "GO:0031369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031369", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4S6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4S6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 2 complex", "id": "GO:0005850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005850", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4S6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4S6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T4S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4S6" }, { "id": "SM00653", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00653" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Translation initiation factor IF2/IF5", "eco_id": "ECO_0000259", "start_pos": 199, "end_pos": 308, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 }, { "start_pos": 221, "end_pos": 223 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T4T1-1", "uniprot_ac": "A0A4X1T4T1", "uniprot_id": "A0A4X1T4T1_PIG", "mass": { "chemical_mass": 50071.0, "monoisotopic_mass": 50071.0 }, "refseq": {}, "gene_names": [ { "name": "HTR3B", "type": "recommended", "evidence": [ { "id": "A0A4X1T4T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ] } ], "protein_names": [ { "name": "5-hydroxytryptamine receptor 3B", "type": "recommended", "evidence": [ { "id": "A0A4X1T4T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1/entry#names_and_taxonomy" } ] }, { "name": "Serotonin receptor 3B", "type": "synonym", "evidence": [ { "id": "A0A4X1T4T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1#function" }, { "database": "UniProtKB", "id": "ARBA00037540", "url": "https://www.uniprot.org/uniprotkb/ARBA00037540#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HTR3B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1", "locus": { "chromosome": "9", "start_pos": 41556738, "end_pos": 41512374, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015053", "url": "https://www.ensembl.org/id/ENSSSCG00000015053" } ] } } ], "crossref": [ { "id": "A0A4X1T4T1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T4T1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR18945", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18945", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02932", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02932", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-112314", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112314", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T4T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "TLASAMSPLWPFVLAAASGILAIDYPRPRSSTLHQLTKQLLQKYHKEVRPVHNWTQATTVYLDVFVHAVLDVDAQNQKVKTSVWYCEVWNDEFLSWNSSMFDEIREISLPLSAVWAPDIIINEFVDIERSPDLPYVYVNSSGTIKHSKPIQMVSACSLETYAFPFDIQNCSLTFSSILHTVEDVDLAFLRSREDIMHNQKAFLNDSEWELLSVSSTYNILQSSAGDFAQIQFNVVIRRRPLAYVVSLLIPSIFLMLVDLGSFYLPPTCRARIVFKSSVLVGYTVFRVNMSDEVPRSTVSTPLIEVFFTVCMAFLVLSLSKSILSVKFLHDERCSQQEQTLLCFRGDADADGPGMDPRAQRAGVTEPPVCQEHQAQSGALKEVWSQLQSISSYLQTQDQEHQQEAGWLALLGRFDRLLFQSYLVVLGLYTVTLCSLWASWSHL", "length": 442, "header": "tr|A0A4X1T4T1-1|A0A4X1T4T1_PIG Isoform 1 of 5-hydroxytryptamine receptor 3B OS=Sus scrofa OX=9823 GN=HTR3B PE=3 SV=1 CANONICAL=A0A4X1T4T1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T4T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1/entry#A0A4X1T4T1-1", "sequence": { "sequence": "TLASAMSPLWPFVLAAASGILAIDYPRPRSSTLHQLTKQLLQKYHKEVRPVHNWTQATTVYLDVFVHAVLDVDAQNQKVKTSVWYCEVWNDEFLSWNSSMFDEIREISLPLSAVWAPDIIINEFVDIERSPDLPYVYVNSSGTIKHSKPIQMVSACSLETYAFPFDIQNCSLTFSSILHTVEDVDLAFLRSREDIMHNQKAFLNDSEWELLSVSSTYNILQSSAGDFAQIQFNVVIRRRPLAYVVSLLIPSIFLMLVDLGSFYLPPTCRARIVFKSSVLVGYTVFRVNMSDEVPRSTVSTPLIEVFFTVCMAFLVLSLSKSILSVKFLHDERCSQQEQTLLCFRGDADADGPGMDPRAQRAGVTEPPVCQEHQAQSGALKEVWSQLQSISSYLQTQDQEHQQEAGWLALLGRFDRLLFQSYLVVLGLYTVTLCSLWASWSHL", "length": 442, "header": "tr|A0A4X1T4T1-1|A0A4X1T4T1_PIG Isoform 1 of 5-hydroxytryptamine receptor 3B OS=Sus scrofa OX=9823 GN=HTR3B PE=3 SV=1 CANONICAL=A0A4X1T4T1-1" }, "locus": { "chromosome": "9", "start_pos": 41553516, "end_pos": 41512614, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016419.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016419.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015978.4", "url": "https://www.ensembl.org/id/ENSSSCP00000015978.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-112314", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112314", "resource": "Reactome", "description": "Neurotransmitter receptors and postsynaptic signal transmission" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" }, { "name": "serotonin-activated cation-selective channel complex", "id": "GO:1904602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904602", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" }, { "name": "transmembrane transporter complex", "id": "GO:1902495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902495", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serotonin-gated monoatomic cation channel activity", "id": "GO:0022850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022850", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" }, { "name": "transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1904315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" }, { "name": "excitatory extracellular ligand-gated monoatomic ion channel activity", "id": "GO:0005231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005231", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" }, { "name": "serotonin-gated cation-selective signaling pathway", "id": "GO:0140227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140227", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] }, { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] }, { "id": "34963", "name": "", "equation": "Na(+)(in) = Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34963" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T4T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" }, { "id": "PF02931", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02931" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Neurotransmitter-gated ion-channel ligand-binding", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 240, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T4T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4T1" }, { "id": "PF02932", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02932" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Neurotransmitter-gated ion-channel transmembrane", "eco_id": "ECO_0000259", "start_pos": 247, "end_pos": 332, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 288, "end_pos": 290 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T4U0-1", "uniprot_ac": "A0A4X1T4U0", "uniprot_id": "A0A4X1T4U0_PIG", "mass": { "chemical_mass": 15258.0, "monoisotopic_mass": 15258.0 }, "refseq": { "ac": "XP_001928539", "name": "glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928539" }, "gene_names": [ { "name": "GATC", "type": "recommended", "evidence": [ { "id": "A0A4X1T4U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0" } ] }, { "name": "GATC", "type": "synonym", "evidence": [ { "id": "XP_001928539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928539" } ] } ], "protein_names": [ { "name": "Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A4X1T4U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0/entry#names_and_taxonomy" } ] }, { "name": "6.3.5.-", "type": "synonym", "evidence": [ { "id": "A0A4X1T4U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0/entry#names_and_taxonomy" } ] }, { "name": "Glu-AdT subunit C", "type": "synonym", "evidence": [ { "id": "A0A4X1T4U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0/entry#names_and_taxonomy" } ] }, { "name": "glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_001928539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928539" } ] } ], "function": [ { "annotation": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4U0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0#function" }, { "database": "HAMAP", "id": "MF_03149", "url": "https://hamap.expasy.org/signature/MF_03149" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4U0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GATC", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0", "locus": { "chromosome": "14", "start_pos": 40423628, "end_pos": 40414017, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000032747", "url": "https://www.ensembl.org/id/ENSSSCG00000032747" } ] } } ], "crossref": [ { "id": "A0A4X1T4U0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T4U0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100153423", "url": "https://www.ncbi.nlm.nih.gov/gene/100153423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153423", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T4U0", "url": "https://www.orthodb.org/?gene=A0A4X1T4U0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15004", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15004", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15004:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15004:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001928539", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928539", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17521", "url": "https://www.rhea-db.org/rhea/17521", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T4U0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T4U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWARAVWLGLRASAGAFRGFTSKADLQGSGRITAELVEHLERLALVDFGNQEAVARLEKAIAFADRLRDVDTDGVEPMDSVLEDRCLYLRSDNVVEGNCAEELLQNSHRVVEEYFVAPPGNISWSKLDEKEPFSFR", "length": 136, "header": "tr|A0A4X1T4U0-1|A0A4X1T4U0_PIG Isoform 1 of Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial OS=Sus scrofa OX=9823 GN=GATC PE=1 SV=1 CANONICAL=A0A4X1T4U0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T4U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0/entry#A0A4X1T4U0-1", "sequence": { "sequence": "MWARAVWLGLRASAGAFRGFTSKADLQGSGRITAELVEHLERLALVDFGNQEAVARLEKAIAFADRLRDVDTDGVEPMDSVLEDRCLYLRSDNVVEGNCAEELLQNSHRVVEEYFVAPPGNISWSKLDEKEPFSFR", "length": 136, "header": "tr|A0A4X1T4U0-1|A0A4X1T4U0_PIG Isoform 1 of Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial OS=Sus scrofa OX=9823 GN=GATC PE=1 SV=1 CANONICAL=A0A4X1T4U0-1" }, "locus": { "chromosome": "14", "start_pos": 40423006, "end_pos": 40414028, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071018.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071018.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068397.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068397.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4U0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153423", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4U0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0" } ], "pmid": "" }, { "name": "glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity", "id": "GO:0050567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050567", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4U0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4U0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0" } ], "pmid": "" }, { "name": "glutamyl-tRNA(Gln) amidotransferase complex", "id": "GO:0030956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030956", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4U0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4U0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0" } ], "pmid": "" }, { "name": "glutaminyl-tRNAGln biosynthesis via transamidation", "id": "GO:0070681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070681", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4U0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0" } ], "pmid": "" }, { "name": "regulation of translational fidelity", "id": "GO:0006450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006450", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T4U0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T4U0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17521", "name": "", "equation": "L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17521", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17521" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T574-1", "uniprot_ac": "A0A4X1T574", "uniprot_id": "A0A4X1T574_PIG", "mass": { "chemical_mass": 13682.0, "monoisotopic_mass": 13682.0 }, "refseq": {}, "gene_names": [ { "name": "CCL16", "type": "recommended", "evidence": [ { "id": "A0A4X1T574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" } ] } ], "protein_names": [ { "name": "C-C motif chemokine", "type": "recommended", "evidence": [ { "id": "A0A4X1T574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T574", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CCL16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574", "locus": { "chromosome": "12", "start_pos": 39621409, "end_pos": 39618414, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040940", "url": "https://www.ensembl.org/id/ENSSSCG00000040940" } ] } } ], "crossref": [ { "id": "A0A4X1T574", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T574", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00272", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00272", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12015:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12015:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00048", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00048", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-380108", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380108", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T574", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T574-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVSVASLFLLILILATTSALRGQERIPDWVNPPPTCCLTYHEKVLPRKLVVGYKKAFNCHLPAIIFITKRNREICTNPDDKWVQKYIKDPKLSLQPSRVSAVDILRSEKGPPQLFNSPR", "length": 120, "header": "tr|A0A4X1T574-1|A0A4X1T574_PIG Isoform 1 of C-C motif chemokine OS=Sus scrofa OX=9823 GN=CCL16 PE=3 SV=1 CANONICAL=A0A4X1T574-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T574-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574/entry#A0A4X1T574-1", "sequence": { "sequence": "MKVSVASLFLLILILATTSALRGQERIPDWVNPPPTCCLTYHEKVLPRKLVVGYKKAFNCHLPAIIFITKRNREICTNPDDKWVQKYIKDPKLSLQPSRVSAVDILRSEKGPPQLFNSPR", "length": 120, "header": "tr|A0A4X1T574-1|A0A4X1T574_PIG Isoform 1 of C-C motif chemokine OS=Sus scrofa OX=9823 GN=CCL16 PE=3 SV=1 CANONICAL=A0A4X1T574-1" }, "locus": { "chromosome": "12", "start_pos": 39621409, "end_pos": 39618414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057598.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057598.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059006.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059006.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T574", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-380108", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380108", "resource": "Reactome", "description": "Chemokine receptors bind chemokines" }, { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T574", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T574", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T574", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" } ], "pmid": "" }, { "name": "antimicrobial humoral immune response mediated by antimicrobial peptide", "id": "GO:0061844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061844", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T574", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" } ], "pmid": "" }, { "name": "chemokine-mediated signaling pathway", "id": "GO:0070098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070098", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T574", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" } ], "pmid": "" }, { "name": "eosinophil chemotaxis", "id": "GO:0048245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048245", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T574", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chemoattractant activity", "id": "GO:0042056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042056", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T574", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" } ], "pmid": "" }, { "name": "chemokine activity", "id": "GO:0008009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008009", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T574", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" } ], "pmid": "" }, { "name": "CCR chemokine receptor binding", "id": "GO:0048020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T574", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T574" }, { "id": "SM00199", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00199" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chemokine interleukin-8-like", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 91, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T5A1-1", "uniprot_ac": "A0A4X1T5A1", "uniprot_id": "A0A4X1T5A1_PIG", "mass": { "chemical_mass": 21444.0, "monoisotopic_mass": 21444.0 }, "refseq": { "ac": "XP_020948336", "name": "WASH complex subunit 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948336" }, "gene_names": [ { "name": "WASHC3", "type": "recommended", "evidence": [ { "id": "A0A4X1T5A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1" } ] }, { "name": "WASHC3", "type": "synonym", "evidence": [ { "id": "XP_020948336", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948336" } ] } ], "protein_names": [ { "name": "WASH complex subunit 3", "type": "recommended", "evidence": [ { "id": "A0A4X1T5A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 53", "type": "synonym", "evidence": [ { "id": "A0A4X1T5A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1/entry#names_and_taxonomy" } ] }, { "name": "WASH complex subunit 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020948336", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948336" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5A1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "WASHC3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1", "locus": { "chromosome": "5", "start_pos": 82217300, "end_pos": 82155256, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036075", "url": "https://www.ensembl.org/id/ENSSSCG00000036075" } ] } } ], "crossref": [ { "id": "A0A4X1T5A1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T5A1", "database": "AlphaFoldDB", "categories": [] }, { "id": "102165500", "url": "https://www.ncbi.nlm.nih.gov/gene/102165500", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:102165500", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102165500", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GCETKFV", "url": "https://omabrowser.org/oma/group/GCETKFV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T5A1", "url": "https://www.orthodb.org/?gene=A0A4X1T5A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13015:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13015:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10152", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10152", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020948336", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948336", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T5A1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T5A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0VYH9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0VYH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0VYH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0VYH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1A1Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8D1A1Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1A1Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1A1Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLDDVTFEVSPISVTRITNESHSETTSEQLQQNSFQDSGPQESEVTPENTLTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLDPDLLERPDAPVPDGEGEKNTEESSDSESSFSD", "length": 194, "header": "tr|A0A4X1T5A1-1|A0A4X1T5A1_PIG Isoform 1 of WASH complex subunit 3 OS=Sus scrofa OX=9823 GN=WASHC3 PE=1 SV=1 CANONICAL=A0A4X1T5A1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T5A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1/entry#A0A4X1T5A1-1", "sequence": { "sequence": "MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLDDVTFEVSPISVTRITNESHSETTSEQLQQNSFQDSGPQESEVTPENTLTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLDPDLLERPDAPVPDGEGEKNTEESSDSESSFSD", "length": 194, "header": "tr|A0A4X1T5A1-1|A0A4X1T5A1_PIG Isoform 1 of WASH complex subunit 3 OS=Sus scrofa OX=9823 GN=WASHC3 PE=1 SV=1 CANONICAL=A0A4X1T5A1-1" }, "locus": { "chromosome": "5", "start_pos": 82216296, "end_pos": 82155379, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096084.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096084.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078083.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078083.1" } ] } }, { "isoform_ac": "A0A8D0VYH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1/entry#A0A8D0VYH9-1", "sequence": { "sequence": "MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEVGPVQMTKTRFTVCVFIYRDLFSPNYYVNIP", "length": 81, "header": "tr|A0A8D0VYH9-1|A0A4X1T5A1_PIG Computationally mapped isoform of WASH complex subunit 3 OS=Sus scrofa OX=9823 GN=WASHC3 PE=1 SV=1 CANONICAL=A0A4X1T5A1-1" }, "locus": { "chromosome": "5", "start_pos": 82156235, "end_pos": 82155379, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091482.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091482.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066999.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066999.1" } ] } }, { "isoform_ac": "A0A8D1A1Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1/entry#A0A8D1A1Z2-1", "sequence": { "sequence": "MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLDDVTFEVSPISVTRITNESHSETTSEQLQQNSFQDSGPQESEVTPENTLTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLDPDLLEPWCMGNLLYHDLS", "length": 180, "header": "tr|A0A8D1A1Z2-1|A0A4X1T5A1_PIG Computationally mapped isoform of WASH complex subunit 3 OS=Sus scrofa OX=9823 GN=WASHC3 PE=1 SV=1 CANONICAL=A0A4X1T5A1-1" }, "locus": { "chromosome": "5", "start_pos": 82201926, "end_pos": 82155379, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081402.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081402.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069640.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069640.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0VYH9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0VYH9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102165500", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102165500", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SU74-1", "protein_name": "WASH complex subunit 3", "gene_name": "WASHC3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLDDVTFEVSPVNVTRITNGTHSEATSEQSQQNSLQDSGPQESEVTPENILTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLDPDLLERPDAPVPDGEGEKNTEESSDSESSFSD", "length": 194 }, "evidence": [ { "id": "A0A4X1T5A1", "url": "https://omabrowser.org/oma/group/A0A4X1T5A1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZKX1-1", "protein_name": "WASH complex subunit 3", "gene_name": "Washc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSAVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLEDVTVDMSPLSVTAVTNGSHSETTAEQLQQNSTQDSGVQQGEAPSENVLTVAKDPRYARYLKMVQVGVPVMAIRDKMISEGLDPELLEKPDAPVPSGESEKAIEESSESTQVPQVSHSILTCWRDDKSHRRCKYFLWLRALENPISRSHKLRL", "length": 232 }, "evidence": [ { "id": "A0A4X1T5A1", "url": "https://omabrowser.org/oma/group/A0A4X1T5A1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5RGJ6-1", "protein_name": "WASH complex subunit 3", "gene_name": "washc3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDADGLPIVGSGVDLTKVPAIQQRRIVAFLNQFIVHTVRFLNRFSTVCEEKLSTVSLRIQQIETTLSILEAKLASIPGLEEVTVDGVRAPAETNGPAADTSRATAPPAEASQQTQAAPQEPKTEAPAENIMTVAKDPRYARYLKMVQVGVPVMAIKNKMMMEGLDPNLLDTPDAAVPDASKKRLEEQDDDSSGSESSFSD", "length": 200 }, "evidence": [ { "id": "A0A4X1T5A1", "url": "https://omabrowser.org/oma/group/A0A4X1T5A1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CR27-1", "protein_name": "WASH complex subunit 3", "gene_name": "Washc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSAVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLEDVTVEVSPLNVTAVTNGSHSETTSEQTQQNSTQDSGAQESEAPSENVLTVAKDPRYARYLKMVQVGVPVMAIRDKMISEGLDPELLEKPDAPVPNGESERAVEESSDSDSSFSD", "length": 194 }, "evidence": [ { "id": "A0A4X1T5A1", "url": "https://omabrowser.org/oma/group/A0A4X1T5A1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VLT8-1", "protein_name": "WASH complex subunit 3", "gene_name": "CCDC53", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDATAAITGNVDKTQIPPLNQKRILAFVNHFLVSTCTFLNEFALGCETKFVEMERQLQKTEAALIILEAKLASIPTEHHVATEATEAPAISNQQRNEEASMVDTTEPPTTENPTEPELPPESVGVRACEDQRYRKFFKMVQVGVPAPAVKQKMQSEGLEPRILDTPDLILADGQRE", "length": 176 }, "evidence": [ { "id": "A0A4X1T5A1", "url": "https://omabrowser.org/oma/group/A0A4X1T5A1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y3C0-1", "protein_name": "WASH complex subunit 3", "gene_name": "WASHC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLDDVTVEVSPLNVTSVTNGAHPEATSEQPQQNSTQDSGLQESEVSAENILTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLDPDLLERPDAPVPDGESEKTVEESSDSESSFSD", "length": 194 }, "evidence": [ { "id": "A0A4X1T5A1", "url": "https://omabrowser.org/oma/group/A0A4X1T5A1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5A1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5A1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "WASH complex", "id": "GO:0071203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071203", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5A1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5A1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T5L6-1", "uniprot_ac": "A0A4X1T5L6", "uniprot_id": "A0A4X1T5L6_PIG", "mass": { "chemical_mass": 39862.0, "monoisotopic_mass": 39862.0 }, "refseq": {}, "gene_names": [ { "name": "SPESP1", "type": "recommended", "evidence": [ { "id": "A0A4X1T5L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5L6" } ] } ], "protein_names": [ { "name": "Sperm equatorial segment protein 1", "type": "recommended", "evidence": [ { "id": "A0A4X1T5L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5L6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in fertilization ability of sperm.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5L6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5L6#function" }, { "database": "UniProtKB", "id": "ARBA00003615", "url": "https://www.uniprot.org/uniprotkb/ARBA00003615#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5L6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5L6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SPESP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5L6", "locus": { "chromosome": "1", "start_pos": 166841693, "end_pos": 166818037, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000032244", "url": "https://www.ensembl.org/id/ENSSSCG00000032244" } ] } } ], "crossref": [ { "id": "A0A4X1T5L6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T5L6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TESTAFW", "url": "https://omabrowser.org/oma/group/TESTAFW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR31667", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31667", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31667:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31667:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1T5L6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T5L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5L6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFLVLLVALLLWPSSLQAYPRITVTPEEEQNLNHYVQVLQNLILSVPTKEPGRQKKSKSPNNVNSVGPRVSKFREIITHEEGSAENDVLINPVTEETTTFPTRGFTLEIEKQRSTKSTAFWSIKPNNISVVLHAKEPYIEKEELEPEPEPTVSQTEPGKSSPDVHESFTSQVVTPSTKDIDLNTIPEDVPQLSGDYEWENPEPENPYNEDILKKISDIDSQVQQVPLPESFKPEYRADIQASKEHLKRSLALAAAAEHKLEKMYKSQMLPLGRSSGGIDDIETVINMLYNSRSKLSEYLDIQYVPPEMRKKAIAVFSILKNILCVNKGETQNLIRKLLNNNIKIINLLNIP", "length": 352, "header": "tr|A0A4X1T5L6-1|A0A4X1T5L6_PIG Isoform 1 of Sperm equatorial segment protein 1 OS=Sus scrofa OX=9823 GN=SPESP1 PE=3 SV=1 CANONICAL=A0A4X1T5L6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T5L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5L6/entry#A0A4X1T5L6-1", "sequence": { "sequence": "MKFLVLLVALLLWPSSLQAYPRITVTPEEEQNLNHYVQVLQNLILSVPTKEPGRQKKSKSPNNVNSVGPRVSKFREIITHEEGSAENDVLINPVTEETTTFPTRGFTLEIEKQRSTKSTAFWSIKPNNISVVLHAKEPYIEKEELEPEPEPTVSQTEPGKSSPDVHESFTSQVVTPSTKDIDLNTIPEDVPQLSGDYEWENPEPENPYNEDILKKISDIDSQVQQVPLPESFKPEYRADIQASKEHLKRSLALAAAAEHKLEKMYKSQMLPLGRSSGGIDDIETVINMLYNSRSKLSEYLDIQYVPPEMRKKAIAVFSILKNILCVNKGETQNLIRKLLNNNIKIINLLNIP", "length": 352, "header": "tr|A0A4X1T5L6-1|A0A4X1T5L6_PIG Isoform 1 of Sperm equatorial segment protein 1 OS=Sus scrofa OX=9823 GN=SPESP1 PE=3 SV=1 CANONICAL=A0A4X1T5L6-1" }, "locus": { "chromosome": "1", "start_pos": 166839531, "end_pos": 166818222, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057533.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057533.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050846.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050846.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5L6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5L6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0JPP4-1", "protein_name": "Sperm equatorial segment protein 1", "gene_name": "Spesp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPVVLVALLWLWPSSFLAYPTATVLPDEEQNLNHYVQILQNLIMSVPTKEQGFGRKFRSSRTVDGAEARSLSSEMLLTPGLVSAQEVTTPETEVMLTSMVEKTTFPSSGFTMESEKRRTHSKAFWSIQPNNVSIVLHTEEPYIEKEPEPEPELETEEESRRLATEPEPEPESESAPETETRQTAESEEEVETSTAQNKVRTGTSRMSTVITQTTNTQGTPNTVTVKTINNLDVSTESEDVPQLSGQSEILNVEDLPGHHSLSTRHENILRKISNINSQIHQGLLSDHSSPAYKEFIKASREHLKRSLALAAAAEHKLQQMYGSNVFLDGHTSDPDDDMEVIINMLYNSRSKLSDYFTINHVPSELREKATVVIAVLKKILCVDQVEMQSLIRKLLSNNMKILNILNVP", "length": 409 }, "evidence": [ { "id": "A0A4X1T5L6", "url": "https://omabrowser.org/oma/group/A0A4X1T5L6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32KL7-1", "protein_name": "Sperm equatorial segment protein 1", "gene_name": "SPESP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKFLVLLVALLLWPSSLPAYRRVTVTPDEEQNLNHYVQVLQNLILSVPTKEPGRQKKSKSPNNANFIGPRVSRVKELKYTHDVGPGDNDVLINPVSEETTTFPTRGFTLEIDKKKRTKSTAFWSIKPSNVSVVLHAKEPFIEKDEPEPEPEPEPEPEPVEHRTGAPTQVPSVTEPSQDVTSLSGSTDLGTATEEEDVPQLSGDNEMDYLESHDMYNEDVLKRIADINSQLHHVPLPESYKPEYRADIRASKEHLKRSLALAIAAEHKLEKMYKSQMLPQGRSSGGVYDIITVINMLYNSRYKLSEYLDIKYVPLEMRGKATVVVHTLKRILCVGHGEETHNLLKQLLNNNIRILHILDTHDKDDSS", "length": 366 }, "evidence": [ { "id": "A0A4X1T5L6", "url": "https://omabrowser.org/oma/group/A0A4X1T5L6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6UW49-1", "protein_name": "Sperm equatorial segment protein 1", "gene_name": "SPESP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPLVLLVALLLWPSSVPAYPSITVTPDEEQNLNHYIQVLENLVRSVPSGEPGREKKSNSPKHVYSIASKGSKFKELVTHGDASTENDVLTNPISEETTTFPTGGFTPEIGKKKHTESTPFWSIKPNNVSIVLHAEEPYIENEEPEPEPEPAAKQTEAPRMLPVVTESSTSPYVTSYKSPVTTLDKSTGIGISTESEDVPQLSGETAIEKPEEFGKHPESWNNDDILKKILDINSQVQQALLSDTSNPAYREDIEASKDHLKRSLALAAAAEHKLKTMYKSQLLPVGRTSNKIDDIETVINMLCNSRSKLYEYLDIKCVPPEMREKAATVFNTLKNMCRSRRVTALLKVY", "length": 350 }, "evidence": [ { "id": "A0A4X1T5L6", "url": "https://omabrowser.org/oma/group/A0A4X1T5L6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D5A0-1", "protein_name": "Sperm equatorial segment protein 1", "gene_name": "Spesp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVVLVALWLWPSSLLAYPTITVLPDEEQNLNHYVHILQNLIMSVPTKEQDLGKKLSSSRTVDSAEPRSLASKVLLTPGLVSAQDVTPESDVLIRPVDETTNSRTRGFTLRRRRTQSTAFWSIRPNNISVVLRTEEPFIEKEPEPELESSRLPTEPEPELEPEPEPVAESRQMSEPEEELVTSTTPNKELTGTSRISSMATQPANTQATRITVTVKTTSTMDVSTDSEDVPQLSGQSEIPSAEDLPGRHSLNTRHEDILKKISNINAEIQQGLLGGNNSPEFKEFIKASREHLKRSLALAAAAEHKLEQMYGSNVFPEGRTSDPDNDMEMIINMLYNSRSKLSDYFNIKRVPSELREKASVVNAELRKILCVDQVEMQSLIKKLLSNNMKILNILNVP", "length": 399 }, "evidence": [ { "id": "A0A4X1T5L6", "url": "https://omabrowser.org/oma/group/A0A4X1T5L6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fusion of sperm to egg plasma membrane involved in single fertilization", "id": "GO:0007342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007342", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5L6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5L6" } ], "pmid": "" }, { "name": "acrosome reaction", "id": "GO:0007340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007340", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5L6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5L6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T5L6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T626-1", "uniprot_ac": "A0A4X1T626", "uniprot_id": "A0A4X1T626_PIG", "mass": { "chemical_mass": 11343.0, "monoisotopic_mass": 11343.0 }, "refseq": {}, "gene_names": [ { "name": "CCL14", "type": "recommended", "evidence": [ { "id": "A0A4X1T626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626" } ] } ], "protein_names": [ { "name": "C-C motif chemokine", "type": "recommended", "evidence": [ { "id": "A0A4X1T626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T626", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CCL14", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626", "locus": { "chromosome": "12", "start_pos": 39616159, "end_pos": 39611868, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034722", "url": "https://www.ensembl.org/id/ENSSSCG00000034722" } ] } } ], "crossref": [ { "id": "A0A4X1T626", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T626", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00272", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00272", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HIVAYYR", "url": "https://omabrowser.org/oma/group/HIVAYYR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12015:SF110", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12015:SF110", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00048", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00048", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1T626", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T626-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVAVAAVSHLFLLLLLLIAIPLGFQTETSLRPRTYQPTDCCFTHLTRAIPRERISSYYETSSQCPKPGIIFITIIGRFVCANPRDDWVQDYIKELKEI", "length": 99, "header": "tr|A0A4X1T626-1|A0A4X1T626_PIG Isoform 1 of C-C motif chemokine OS=Sus scrofa OX=9823 GN=CCL14 PE=3 SV=1 CANONICAL=A0A4X1T626-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T626-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626/entry#A0A4X1T626-1", "sequence": { "sequence": "MKVAVAAVSHLFLLLLLLIAIPLGFQTETSLRPRTYQPTDCCFTHLTRAIPRERISSYYETSSQCPKPGIIFITIIGRFVCANPRDDWVQDYIKELKEI", "length": 99, "header": "tr|A0A4X1T626-1|A0A4X1T626_PIG Isoform 1 of C-C motif chemokine OS=Sus scrofa OX=9823 GN=CCL14 PE=3 SV=1 CANONICAL=A0A4X1T626-1" }, "locus": { "chromosome": "12", "start_pos": 39615757, "end_pos": 39611940, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041540.1", "url": "https://www.ensembl.org/id/ENSSSCT00000041540.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054819.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054819.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T626", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T626", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T626", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T626", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626" } ], "pmid": "" }, { "name": "antimicrobial humoral immune response mediated by antimicrobial peptide", "id": "GO:0061844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061844", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T626", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626" } ], "pmid": "" }, { "name": "chemokine-mediated signaling pathway", "id": "GO:0070098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070098", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T626", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626" } ], "pmid": "" }, { "name": "cell chemotaxis", "id": "GO:0060326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060326", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T626", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chemokine activity", "id": "GO:0008009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008009", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T626", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626" } ], "pmid": "" }, { "name": "CCR chemokine receptor binding", "id": "GO:0048020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T626", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T626" }, { "id": "SM00199", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00199" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chemokine interleukin-8-like", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 96, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T661-1", "uniprot_ac": "A0A4X1T661", "uniprot_id": "A0A4X1T661_PIG", "mass": { "chemical_mass": 51320.0, "monoisotopic_mass": 51320.0 }, "refseq": { "ac": "XP_013850400", "name": "serine incorporator 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850400" }, "gene_names": [ { "name": "SERINC5", "type": "recommended", "evidence": [ { "id": "A0A4X1T661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ] }, { "name": "SERINC5", "type": "synonym", "evidence": [ { "id": "XP_013850400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850400" } ] } ], "protein_names": [ { "name": "Serine incorporator 5", "type": "recommended", "evidence": [ { "id": "A0A4X1T661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661/entry#names_and_taxonomy" } ] }, { "name": "serine incorporator 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013850400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850400" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SERINC5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661", "locus": { "chromosome": "2", "start_pos": 88843011, "end_pos": 89046026, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014119", "url": "https://www.ensembl.org/id/ENSSSCG00000014119" } ] } } ], "crossref": [ { "id": "A0A4X1T661", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T661", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014119", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014119", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100624743", "url": "https://www.ncbi.nlm.nih.gov/gene/100624743", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624743", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624743", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GCTFNKI", "url": "https://omabrowser.org/oma/group/GCTFNKI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T661", "url": "https://www.orthodb.org/?gene=A0A4X1T661", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10383", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10383", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10383:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10383:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03348", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03348", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-977347", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-977347", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013850400", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850400", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "38571", "url": "https://www.rhea-db.org/rhea/38571", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38663", "url": "https://www.rhea-db.org/rhea/38663", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38895", "url": "https://www.rhea-db.org/rhea/38895", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T661-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPJ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAQCCAGQLACCCGNAGCSFCCGCCPKIRQSRSTRFMYALYFILVVILCCIMMSNTVANEMRERIPFFEDICKGIKAGDTCEKLVGYSAVYRVCFGMACFFFIFCLLTLKVNNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNAWRYVGAIGGFLFIGIQLLLIVEFAHKWNKNWTAGTATNKLWYACLSLVTLIMYSIATGGLILMAVFYTQKDGCMENKILLGVNGGLCLLISVVAISPCVQDRQPHSGLLQSGLISCYVTYLTFSALSSKPVEVVLDEHGKNVTICVPDFGQDLYRDKNLVAGLGTSLLCACILYSCLTSTTRSSSDALQGRYGAPELEVARCCFCFSSGGEDTEEQQNVKEGPRVIYDEKKSTVYTYSYFHFVFFLASLYVMMTITNWFNYESANIESFFSGSWSIFWVKMASCWICVLLYLGTLIAPLCRPSPQFSV", "length": 461, "header": "tr|A0A4X1T661-1|A0A4X1T661_PIG Isoform 1 of Serine incorporator 5 OS=Sus scrofa OX=9823 GN=SERINC5 PE=3 SV=1 CANONICAL=A0A4X1T661-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T661-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661/entry#A0A4X1T661-1", "sequence": { "sequence": "MSAQCCAGQLACCCGNAGCSFCCGCCPKIRQSRSTRFMYALYFILVVILCCIMMSNTVANEMRERIPFFEDICKGIKAGDTCEKLVGYSAVYRVCFGMACFFFIFCLLTLKVNNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNAWRYVGAIGGFLFIGIQLLLIVEFAHKWNKNWTAGTATNKLWYACLSLVTLIMYSIATGGLILMAVFYTQKDGCMENKILLGVNGGLCLLISVVAISPCVQDRQPHSGLLQSGLISCYVTYLTFSALSSKPVEVVLDEHGKNVTICVPDFGQDLYRDKNLVAGLGTSLLCACILYSCLTSTTRSSSDALQGRYGAPELEVARCCFCFSSGGEDTEEQQNVKEGPRVIYDEKKSTVYTYSYFHFVFFLASLYVMMTITNWFNYESANIESFFSGSWSIFWVKMASCWICVLLYLGTLIAPLCRPSPQFSV", "length": 461, "header": "tr|A0A4X1T661-1|A0A4X1T661_PIG Isoform 1 of Serine incorporator 5 OS=Sus scrofa OX=9823 GN=SERINC5 PE=3 SV=1 CANONICAL=A0A4X1T661-1" }, "locus": { "chromosome": "2", "start_pos": 88960959, "end_pos": 88847821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015423.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015423.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015014.5", "url": "https://www.ensembl.org/id/ENSSSCP00000015014.5" } ] } }, { "isoform_ac": "A0A5G2QPJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661/entry#A0A5G2QPJ6-1", "sequence": { "sequence": "MYALYFILVVILCCIMMSNTVANEMRERIPFFEDICKGIKAGDTCEKLVGYSAVYRVCFGMACFFFIFCLLTLKVNNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNAWRYVGAIGGFLFIGIQLLLIVEFAHKWNKNWTAGTATNKLWYACLSLVTLIMYSIATGGLILMAVFYTQKDGCMENKILLGVNGGLCLLISVVAISPCVQDRQPHSGLLQSGLISCYVTYLTFSALSSKPVEVVLDEHGKNVTICVPDFGQDLYRDKNLVAGLGTSLLCACILYSCLTSTTRSSSDALQGRYGAPELEVARCCFCFSSGGEDTEEQQNVKEGPRVIYDEKKSTVYTYSYFHFVFFLASLYVMMTITNWFNYESANIESFFSGSWSIFWVKMASCWICVLLYLGTLIAPLCRPSPQFSV", "length": 424, "header": "tr|A0A5G2QPJ6-1|A0A5G2QPJ6_PIG Computationally mapped isoform of Serine incorporator 5 OS=Sus scrofa OX=9823 GN=SERINC5 PE=3 SV=1 CANONICAL=A0A4X1T661-1" }, "locus": { "chromosome": "2", "start_pos": 88900704, "end_pos": 88847821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072280.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072280.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065986.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065986.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624743", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624743", "resource": "KEGG Pathway" }, { "id": "R-SSC-977347", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-977347", "resource": "Reactome", "description": "Serine metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1P8B1A7-1", "protein_name": "Serinc-domain containing serine and sphingolipid biosynthesis protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNGSAEATRTRPLQISPGDLEAAHLDELIMEIEQRSLYYYQEKNKSLRARYTYGTIFLIINLCAWFIRDYAQKALALLPYVSSCGPEGSRCFHTLGVLRVSLGCFIFYFVMFLSTWNTMKLHEAQNSWHSDNWIFKFFLLVIVMVASFFIPQLYIQIYGEIARVGAGIFLGLQLVSVIEFITWWNNYWMPQNQSKQSCSFGLVMSIVFYIGSVCGIAVMYYFYGASTACGLNIFFISWTVILLIVMMVISLHSKVKNRGLLSSGIMASYIVFLCWSAIRSEPSHTKCNAHTQNSHTDWTTILSFLIAIGAIVMATFSTGIDSESFRFEFRKDEAKEEDDIPYSYGFFHLVFSLGAMYFAMLFISWNLSHSTEKWSIDVGWTSTWVKIVNEWFAAAIYLWKLIAPIVRQHRVHEQPQPTAAEVHR", "length": 424 }, "evidence": [ { "id": "A0A4X1T661", "url": "https://omabrowser.org/oma/group/A0A4X1T661/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A3Q1LF32-1", "protein_name": "Serine incorporator 5", "gene_name": "SERINC5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSARCCAGQLACCCGNAGCSYCCGPKVRQSRSTRFMYALYFILVVIICCIMMSNTVANEMREHIPYFEDICKGIKAGDTCEKLVGYSAVYRVCFGMACFFFIFCLLTLNINNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNAWRYVGAVGGFLFIVIQLLLLVEFAHKWNKNWTAGTATNKLWYASLSLVTLITYSITTGGLIWMAVFYTQKDGCMENKILLGVNGGLCLLMSVVSISPSVRDRQPHSGILQSGLISCYVTYLTFSALSSKPAEVVLDEHGKNVTICVPNFGQDLYRDKTLVAGLGTAILCVCILYSCLTSTTRSSSDALQGRYTAPELEVARCCFCFGSGGEDAEEKRNMKEGPRVIYDEKKSTVYSYAYFHFMFFLASLYVMMTVTNWFNYESANIETFFSGSWSIFWVKMASCWICVLLYLGTLIAPLCRPSPQYSV", "length": 459 }, "evidence": [ { "id": "A0A4X1T661", "url": "https://omabrowser.org/oma/group/A0A4X1T661/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q63175-1", "protein_name": "Serine incorporator 5", "gene_name": "Serinc5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSARCCAGQLACCCGSAGCALCCGCCPKFRQSRSTRFMYLFYFTLVIIPCCVMMSPSVMKQMTEHIPFFEDFCKGIKAGDTCENLVGYSAVYRVCFGMACFFFVFCVLTFKVNNSKSCRASIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNVWRYVGAVGSFFFICIQLLLIVEFAHKWNKNWTAGTVRNKLWYASLSLALIMYSIAVGGLALMAVFYTQWDDCMDNKILLGVHGGLCVLISLAAISPCVQNRQPHSGLLQPGLISCYVTYLTFSALTSKPEKVVKDEHGKNVTICVPDFGQDFRRDESMVTWLGTLLLVVCISYSCLTSTTRSSSDALQRRYGAPELEVARCCFCFGPDGEDTEEQQNVKEGPRVIYDEKKGTVYSYSYFHFVLLLASLYVMMTLTSWFHYENATIETFFVGSWSIFWVKMASCWMCVLLYLWTLVAPLCCPSRQFSV", "length": 460 }, "evidence": [ { "id": "A0A4X1T661", "url": "https://omabrowser.org/oma/group/A0A4X1T661/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q803X0-1", "protein_name": "Serine incorporator 5", "gene_name": "serinc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCTPCCVSQLACCCGSAACSLCCGCCPKIKQSTSTRFMYALFFMLVTVTCVIMMSPTVEMAMREHIPFYSQMCQQLNAGENCSTLVGYSAVYKVCFGMACFFFFFAVFTIRVQNSTGCRAAVHNGFWFFKFVALLACCAGGFFLPNQDQFLEVWRYVGAAGGFLFIIIQLMLLVQFAHRWNQNWSSGATYNKLWYAALALVTLVLFSVAVGGMVFMFMYYTHPEACFLNKIFLGVNGGLCFIVSLLAISPCIQTFQPTSGLLQPAVITLYVMYLTFSALASKPIEMVEDEIKGNITVCVFPFKSGLKSDTNIVTGVGTAILFCCILYSCLISTTKRSSAALQVYRNDMPENERARCCFCWVDDTEDYDDEKTSGGQNVKYDERDGTVYSYCFFHFVFFLGSLYVMMTVTNWFHYDNAKIERLLEGSWSVFWIKMASSWVCLFFYMWTLVVPMLFPQRFQA", "length": 460 }, "evidence": [ { "id": "A0A4X1T661", "url": "https://omabrowser.org/oma/group/A0A4X1T661/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86VE9-1", "protein_name": "Serine incorporator 5", "gene_name": "SERINC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAQCCAGQLACCCGSAGCSLCCDCCPRIRQSLSTRFMYALYFILVVVLCCIMMSTTVAHKMKEHIPFFEDMCKGIKAGDTCEKLVGYSAVYRVCFGMACFFFIFCLLTLKINNSKSCRAHIHNGFWFFKLLLLGAMCSGAFFIPDQDTFLNAWRYVGAVGGFLFIGIQLLLLVEFAHKWNKNWTAGTASNKLWYASLALVTLIMYSIATGGLVLMAVFYTQKDSCMENKILLGVNGGLCLLISLVAISPWVQNRQPHSGLLQSGVISCYVTYLTFSALSSKPAEVVLDEHGKNVTICVPDFGQDLYRDENLVTILGTSLLIGCILYSCLTSTTRSSSDALQGRYAAPELEIARCCFCFSPGGEDTEEQQPGKEGPRVIYDEKKGTVYIYSYFHFVFFLASLYVMMTVTNWFNHVRSAFHLLP", "length": 423 }, "evidence": [ { "id": "A0A4X1T661", "url": "https://omabrowser.org/oma/group/A0A4X1T661/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BHJ6-1", "protein_name": "Serine incorporator 5", "gene_name": "Serinc5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSARCCAGQLACCCGSAGCSLCCGCCPKFRQSRTTRFMYLFYFILVIALCCVMMTPSVMKQVKDHIPFFEEFCKKTQAGGDACENLVGYSAVYRVCFGMACFFALFCLLTLKVNNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLKVWRYVGAGGSFLFICIQLLLIVQFAHKWNKNWTAGTVRNKLWYASLSLVTLIMYSVAVGGLALMAVFYTQWDDCMDNKILLGVHGGLCVLISLVAISPCVQNRQPHSGLLQSGLISCYVTYLTFSALTSKPEKKVLDEHGKNVTICAPDFGQDLHRDENMVTWLGTLLLIVCISYSCLTSTTRSSSDALQSRYGAPELEVARCCFCFGPDGEDTEEQQNVKKGPRVIYDEKKGTVYSYSYFHFVFFLASLYVMMTLTSWFHYENATIKTFFSGWSVFWVKMASCWMCVLLYLQTLVAPLCCPSRQFSV", "length": 461 }, "evidence": [ { "id": "A0A4X1T661", "url": "https://omabrowser.org/oma/group/A0A4X1T661/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ], "pmid": "" }, { "name": "myelin sheath", "id": "GO:0043209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043209", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phospholipid scramblase activity", "id": "GO:0017128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017128", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T661", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T661" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "38571", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "38571", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38571" } ] }, { "id": "38663", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "38663", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38663" } ] }, { "id": "38895", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "38895", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38895" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 294, "end_pos": 296 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T674-1", "uniprot_ac": "A0A4X1T674", "uniprot_id": "A0A4X1T674_PIG", "mass": { "chemical_mass": 70097.0, "monoisotopic_mass": 70097.0 }, "refseq": { "ac": "XP_001927994", "name": "D-glucuronyl C5-epimerase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927994" }, "gene_names": [ { "name": "GLCE", "type": "recommended", "evidence": [ { "id": "A0A4X1T674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674" } ] }, { "name": "GLCE", "type": "synonym", "evidence": [ { "id": "XP_001927994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927994" } ] } ], "protein_names": [ { "name": "heparosan-N-sulfate-glucuronate 5-epimerase", "type": "recommended", "evidence": [ { "id": "A0A4X1T674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674/entry#names_and_taxonomy" } ] }, { "name": "5.1.3.17", "type": "synonym", "evidence": [ { "id": "A0A4X1T674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674/entry#names_and_taxonomy" } ] }, { "name": "D-glucuronyl C5-epimerase", "type": "synonym", "evidence": [ { "id": "XP_001927994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927994" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T674", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GLCE", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674", "locus": { "chromosome": "1", "start_pos": 167122186, "end_pos": 167007939, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026078", "url": "https://www.ensembl.org/id/ENSSSCG00000026078" } ] } } ], "crossref": [ { "id": "A0A4X1T674", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T674", "database": "AlphaFoldDB", "categories": [] }, { "id": "100154444", "url": "https://www.ncbi.nlm.nih.gov/gene/100154444", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154444", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154444", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RGVFMYF", "url": "https://omabrowser.org/oma/group/RGVFMYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T674", "url": "https://www.orthodb.org/?gene=A0A4X1T674", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13174:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13174:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001927994", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927994", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20197", "url": "https://www.rhea-db.org/rhea/20197", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T674", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T674-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRCLAARVNYKTLIIICALFTLVTVLLWNKCSSDKAIQFPRHLSSGFRVDALEKRAAASESNNHVNHMAKQSEETFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCLINDEHTIKGRREGNEVFLPFSWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYTQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKSNKLSDWTVPKGCFMASVTDKSRFTNVKQFIAPETSDGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTVHYVSNTQLIAFKERDIYYGIGPRTSWSTITRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHTFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARYLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN", "length": 617, "header": "tr|A0A4X1T674-1|A0A4X1T674_PIG Isoform 1 of heparosan-N-sulfate-glucuronate 5-epimerase OS=Sus scrofa OX=9823 GN=GLCE PE=3 SV=1 CANONICAL=A0A4X1T674-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T674-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674/entry#A0A4X1T674-1", "sequence": { "sequence": "MRCLAARVNYKTLIIICALFTLVTVLLWNKCSSDKAIQFPRHLSSGFRVDALEKRAAASESNNHVNHMAKQSEETFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCLINDEHTIKGRREGNEVFLPFSWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYTQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKSNKLSDWTVPKGCFMASVTDKSRFTNVKQFIAPETSDGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTVHYVSNTQLIAFKERDIYYGIGPRTSWSTITRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHTFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARYLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN", "length": 617, "header": "tr|A0A4X1T674-1|A0A4X1T674_PIG Isoform 1 of heparosan-N-sulfate-glucuronate 5-epimerase OS=Sus scrofa OX=9823 GN=GLCE PE=3 SV=1 CANONICAL=A0A4X1T674-1" }, "locus": { "chromosome": "1", "start_pos": 167118966, "end_pos": 167106454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022924.4", "url": "https://www.ensembl.org/id/ENSSSCT00000022924.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019174.1", "url": "https://www.ensembl.org/id/ENSSSCP00000019174.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T674", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154444", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154444", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1Z6M8-1", "protein_name": "heparosan-N-sulfate-glucuronate 5-epimerase", "gene_name": "Hsepi", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKYLSSQRDALSAPALPVSRENREPPKFQGVKQREPLVFFIMRLNLKAVLLVLTVAVVVITLGVYMRCAAFSFSPDFVRPLDRSARQSSSGGEATALHDIECSINQEYTVHCKRDENANEVYVPFSFLRNYFDVSGAVSTNSNEVAKFNWVHSTAKVNLPRGKYDARGVYMYFENYNVEVRDRVKCISAAEGVPVSTQWEKRGYFYPTQIAQFALSHYSKNLTEPAPRVRVLEDGDGNQMEWSTPKTSNMTRIWHHKFNTSVVQFETAPGYEGVISIALNQTLDLLLSVDLLLVTNSSSLMITVQNRDTRHNYSLHYIPADLLLSVQDTNIYYGLGGSALNKWRHITRDLHIDLQKGIMGDKRSPLKIRRSDLEVISIGFLGLGFFDNITLSTSDHLAHFYDAAEWFVHNQDPKTGGWTNPVRRSLNGFAELRPGWISAMGQGHAISVLARAYWHSGGDERYLRAAAAGLQPYRVYSRDGGVLAQFMDKFYWYEEYPTTPPSYVLNGFIYSLLGLYDLNSTAPGKIAREAGKLFAQGMHSLKKMLLLFDTGSGTSYDLRHLSLGVAPNLARWDYHATHVNQLLLLATIDSDPLIAQTAERWKGYMFGRRAKHN", "length": 614 }, "evidence": [ { "id": "A0A4X1T674", "url": "https://omabrowser.org/oma/group/A0A4X1T674/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZIK0-1", "protein_name": "heparosan-N-sulfate-glucuronate 5-epimerase", "gene_name": "Glce", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRCLAARVNYKTLIIICALFTLVTVLLWNKCSSDKAIQFPRHLSSGFRVDGLEKRSAASESNHYANHIAKQQSEEAFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCLINDEHTIRGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRSPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDRNIRPNEWTVPKGCFMASVADKSRSTNVKQFIAPEAGEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTDKNQLFTVHYVSNTQLIAFKDRDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDYVFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPIFKEFVKRWKSYLKGSRAKHN", "length": 618 }, "evidence": [ { "id": "A0A4X1T674", "url": "https://omabrowser.org/oma/group/A0A4X1T674/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QR43-1", "protein_name": "D-glucuronyl C5-epimerase B", "gene_name": "glceb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMRCLAARVHYKTLIVICALLSLLTVLLWNKCTSEKALRFLPRHPQPPPSPKIDSHPQQPQPPEPPPVVGGVRYEEIDCLINDDATIKGRREGSEVYMPFSWMEKYFEVYGKVVQYDGYDRFEFSHSYSKVYAQREQYHPNGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYAIQIAQYGLSHYSKNLTERPPHVEVYDTAEERDSRSSAWTVPKGCSLTRVYDKTRATSVRQFSAPENSEGVSLPLGNTKDFIISFDLKFTSNGSVSVILETTEKGPPFVIHYVTTTQLILLKDRDITYGIGPRTTWTTVTRDLLTDLRKGIGLSNTKAVKATKTMPRRVVKLVVHGTGTIDNITISTTSHMAAFYAASDWLVRNQDERGGWPIMVTRKLGEGFRALEPGWYSAMAQGQAMSTLVRAYLMTKDDTYLKAALRATGPFKLPSEQHGVKAVFMNKYDWYEEYPTIPSSFVLNGFIYSLIGLFDLAQTAGEKLGRDAGQLYSKGMESLKVMLPLYDTGSGTIYDLRHFILGTAPNLARWDYHTTHINQLQLLGTIDNSPIFRDSVKRWKSYLKGGRAKHN", "length": 586 }, "evidence": [ { "id": "A0A4X1T674", "url": "https://omabrowser.org/oma/group/A0A4X1T674/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O18756-1", "protein_name": "D-glucuronyl C5-epimerase", "gene_name": "GLCE", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRCLAARVNYKTLIIICALFTLVTVLLWNKCSSDKAIQVPRHLSSGFRVDALEKKAAASESNNYVNHMAKQSEEAFPQEQQKAPPVVGGFNNNGGGRVLGLKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKNSKPNDWTVPKGCFMASVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTVHYVSNTQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTRIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPIFKEFVKRWKSYLKGSRAKHN", "length": 617 }, "evidence": [ { "id": "A0A4X1T674", "url": "https://omabrowser.org/oma/group/A0A4X1T674/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O94923-1", "protein_name": "D-glucuronyl C5-epimerase", "gene_name": "GLCE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRCLAARVNYKTLIIICALFTLVTVLLWNKCSSDKAIQFPRRSSSGFRVDGFEKRAAASESNNYMNHVAKQQSEEAFPQEQQKAPPVVGGFNSNVGSKVLGLKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKNKPNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN", "length": 617 }, "evidence": [ { "id": "A0A4X1T674", "url": "https://omabrowser.org/oma/group/A0A4X1T674/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EPS3-1", "protein_name": "D-glucuronyl C5-epimerase", "gene_name": "Glce", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRCLAARVNYKTLIIICALFTLVTVLLWNKCSSDKAIQFPRHLSSGFRVDGLEKRSAASESNHYANHIAKQQSEEAFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRSPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDRNIRPNEWTVPKGCFMASVADKSRSTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKLLTNGSVSVVLETTEKNQLFTVHYVSNTQLIAFRDRDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDYVFLSSALRATAPYKFPSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGETLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPIFKEFVKRWKSYLKGSRAKHN", "length": 618 }, "evidence": [ { "id": "A0A4X1T674", "url": "https://omabrowser.org/oma/group/A0A4X1T674/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T674", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T674", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T674", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T674", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674" } ], "pmid": "" }, { "name": "heparosan-N-sulfate-glucuronate 5-epimerase activity", "id": "GO:0047464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047464", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T674", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "heparin proteoglycan biosynthetic process", "id": "GO:0030210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030210", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T674", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T674", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20197", "name": "", "equation": "[heparosan-N-sulfate](n) = [heparan-N-sulfate](n)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20197", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20197" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674" }, { "id": "PF06662", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06662" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "D-glucuronyl C5-epimerase C-terminal", "eco_id": "ECO_0000259", "start_pos": 416, "end_pos": 607, "start_aa": "Gln", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T674" }, { "id": "PF21174", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "D-glucuronyl C5-epimerase beta-sandwich", "eco_id": "ECO_0000259", "start_pos": 268, "end_pos": 388, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 393, "end_pos": 395 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T6M0-1", "uniprot_ac": "A0A4X1T6M0", "uniprot_id": "A0A4X1T6M0_PIG", "mass": { "chemical_mass": 15096.0, "monoisotopic_mass": 15096.0 }, "refseq": { "ac": "XP_003361930", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003361930" }, "gene_names": [ { "name": "NDUFB4", "type": "recommended", "evidence": [ { "id": "A0A4X1T6M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0" } ] }, { "name": "NDUFB4", "type": "synonym", "evidence": [ { "id": "XP_003361930", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003361930" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "type": "recommended", "evidence": [ { "id": "A0A4X1T6M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0/entry#names_and_taxonomy" } ] }, { "name": "Complex I-B15", "type": "synonym", "evidence": [ { "id": "A0A4X1T6M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0/entry#names_and_taxonomy" } ] }, { "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "type": "synonym", "evidence": [ { "id": "XP_003361930", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003361930" } ] }, { "name": "NADH-ubiquinone oxidoreductase B15 subunit", "type": "synonym", "evidence": [ { "id": "A0A4X1T6M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR1#function" }, { "database": "UniProtKB", "id": "ARBA00003195", "url": "https://www.uniprot.org/uniprotkb/ARBA00003195#function" }, { "database": "UniProtKB", "id": "A0A4X1T6M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NDUFB4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0", "locus": { "chromosome": "13", "start_pos": 139724148, "end_pos": 139730493, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031913", "url": "https://www.ensembl.org/id/ENSSSCG00000031913" } ] } } ], "crossref": [ { "id": "A0A4X1T6M0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T6M0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000031913", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031913", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100624335", "url": "https://www.ncbi.nlm.nih.gov/gene/100624335", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "7V2C", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2C&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2D&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2E", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2E&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2F", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2F&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2H", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2H&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2K", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2K&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V30", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V30&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V31", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V31&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V32", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V32&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V33", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V33&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V3M", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V3M&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VBL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VBL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VBP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VBP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VC0", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VC0&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VWL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VWL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VXS", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VXS&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VY1", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VY1&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VY9", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VY9&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYE", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYE&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYG", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYG&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYI", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYI&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYS", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYS&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZ8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZ8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZV", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZV&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W00", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W00&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W0H", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W0H&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W0R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W0R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W0Y", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W0Y&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1O", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1O&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1P", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1P&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1T", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1T&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1U", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1U&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1V", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1V&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W20", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W20&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2K", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2K&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2L", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2L&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2U", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2U&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2Y", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2Y&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W31", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W31&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W32", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W32&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W35", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W35&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4C", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4C&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4D&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4E", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4E&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4F", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4F&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4G", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4G&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4J", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4J&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4K", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4K&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4L", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4L&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4M", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4M&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4N", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4N&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4Q", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4Q&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UD1", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UD1&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEO", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEO&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UER", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UER&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UES", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UES&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UET", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UET&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEU", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEU&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEV", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEV&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEX", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEX&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEY", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEY&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGI", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGI&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGJ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGJ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZO8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZO8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZOU", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZOU&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZP8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZP8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSK", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSK&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSM", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSM&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSO", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSO&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZXZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZXZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9BUH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9BUH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9BWD", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9BWD&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9BXV", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9BXV&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CD6", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CD6&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CDN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CDN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CE2", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CE2&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9J6H", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9J6H&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9J6W", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9J6W&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR009866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624335", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624335", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "REYLLHY", "url": "https://omabrowser.org/oma/group/REYLLHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T6M0", "url": "https://www.orthodb.org/?gene=A0A4X1T6M0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15469", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15469", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15469:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15469:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00007v2c", "url": "https://www.rcsb.org/structure/pdb_00007v2c", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2d", "url": "https://www.rcsb.org/structure/pdb_00007v2d", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2e", "url": "https://www.rcsb.org/structure/pdb_00007v2e", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2f", "url": "https://www.rcsb.org/structure/pdb_00007v2f", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2h", "url": "https://www.rcsb.org/structure/pdb_00007v2h", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2k", "url": "https://www.rcsb.org/structure/pdb_00007v2k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2r", "url": "https://www.rcsb.org/structure/pdb_00007v2r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v30", "url": "https://www.rcsb.org/structure/pdb_00007v30", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v31", "url": "https://www.rcsb.org/structure/pdb_00007v31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v32", "url": "https://www.rcsb.org/structure/pdb_00007v32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v33", "url": "https://www.rcsb.org/structure/pdb_00007v33", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v3m", "url": "https://www.rcsb.org/structure/pdb_00007v3m", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vbl", "url": "https://www.rcsb.org/structure/pdb_00007vbl", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vbp", "url": "https://www.rcsb.org/structure/pdb_00007vbp", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vc0", "url": "https://www.rcsb.org/structure/pdb_00007vc0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vwl", "url": "https://www.rcsb.org/structure/pdb_00007vwl", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vxs", "url": "https://www.rcsb.org/structure/pdb_00007vxs", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vy1", "url": "https://www.rcsb.org/structure/pdb_00007vy1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vy9", "url": "https://www.rcsb.org/structure/pdb_00007vy9", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vye", "url": "https://www.rcsb.org/structure/pdb_00007vye", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vyg", "url": "https://www.rcsb.org/structure/pdb_00007vyg", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vyi", "url": "https://www.rcsb.org/structure/pdb_00007vyi", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vys", "url": "https://www.rcsb.org/structure/pdb_00007vys", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vz8", "url": "https://www.rcsb.org/structure/pdb_00007vz8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vzv", "url": "https://www.rcsb.org/structure/pdb_00007vzv", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vzw", "url": "https://www.rcsb.org/structure/pdb_00007vzw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w00", "url": "https://www.rcsb.org/structure/pdb_00007w00", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w0h", "url": "https://www.rcsb.org/structure/pdb_00007w0h", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w0r", "url": "https://www.rcsb.org/structure/pdb_00007w0r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w0y", "url": "https://www.rcsb.org/structure/pdb_00007w0y", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1o", "url": "https://www.rcsb.org/structure/pdb_00007w1o", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1p", "url": "https://www.rcsb.org/structure/pdb_00007w1p", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1t", "url": "https://www.rcsb.org/structure/pdb_00007w1t", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1u", "url": "https://www.rcsb.org/structure/pdb_00007w1u", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1v", "url": "https://www.rcsb.org/structure/pdb_00007w1v", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1z", "url": "https://www.rcsb.org/structure/pdb_00007w1z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w20", "url": "https://www.rcsb.org/structure/pdb_00007w20", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2k", "url": "https://www.rcsb.org/structure/pdb_00007w2k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2l", "url": "https://www.rcsb.org/structure/pdb_00007w2l", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2r", "url": "https://www.rcsb.org/structure/pdb_00007w2r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2u", "url": "https://www.rcsb.org/structure/pdb_00007w2u", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2y", "url": "https://www.rcsb.org/structure/pdb_00007w2y", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w31", "url": "https://www.rcsb.org/structure/pdb_00007w31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w32", "url": "https://www.rcsb.org/structure/pdb_00007w32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w35", "url": "https://www.rcsb.org/structure/pdb_00007w35", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4c", "url": "https://www.rcsb.org/structure/pdb_00007w4c", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4d", "url": "https://www.rcsb.org/structure/pdb_00007w4d", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4e", "url": "https://www.rcsb.org/structure/pdb_00007w4e", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4f", "url": "https://www.rcsb.org/structure/pdb_00007w4f", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4g", "url": "https://www.rcsb.org/structure/pdb_00007w4g", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4j", "url": "https://www.rcsb.org/structure/pdb_00007w4j", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4k", "url": "https://www.rcsb.org/structure/pdb_00007w4k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4l", "url": "https://www.rcsb.org/structure/pdb_00007w4l", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4m", "url": "https://www.rcsb.org/structure/pdb_00007w4m", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4n", "url": "https://www.rcsb.org/structure/pdb_00007w4n", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4q", "url": "https://www.rcsb.org/structure/pdb_00007w4q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ud1", "url": "https://www.rcsb.org/structure/pdb_00008ud1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ueo", "url": "https://www.rcsb.org/structure/pdb_00008ueo", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uep", "url": "https://www.rcsb.org/structure/pdb_00008uep", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ueq", "url": "https://www.rcsb.org/structure/pdb_00008ueq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uer", "url": "https://www.rcsb.org/structure/pdb_00008uer", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ues", "url": "https://www.rcsb.org/structure/pdb_00008ues", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uet", "url": "https://www.rcsb.org/structure/pdb_00008uet", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ueu", "url": "https://www.rcsb.org/structure/pdb_00008ueu", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uev", "url": "https://www.rcsb.org/structure/pdb_00008uev", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uew", "url": "https://www.rcsb.org/structure/pdb_00008uew", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uex", "url": "https://www.rcsb.org/structure/pdb_00008uex", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uey", "url": "https://www.rcsb.org/structure/pdb_00008uey", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uez", "url": "https://www.rcsb.org/structure/pdb_00008uez", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugh", "url": "https://www.rcsb.org/structure/pdb_00008ugh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugi", "url": "https://www.rcsb.org/structure/pdb_00008ugi", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugj", "url": "https://www.rcsb.org/structure/pdb_00008ugj", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugn", "url": "https://www.rcsb.org/structure/pdb_00008ugn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugr", "url": "https://www.rcsb.org/structure/pdb_00008ugr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zo8", "url": "https://www.rcsb.org/structure/pdb_00008zo8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zou", "url": "https://www.rcsb.org/structure/pdb_00008zou", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zp8", "url": "https://www.rcsb.org/structure/pdb_00008zp8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsk", "url": "https://www.rcsb.org/structure/pdb_00008zsk", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsl", "url": "https://www.rcsb.org/structure/pdb_00008zsl", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsm", "url": "https://www.rcsb.org/structure/pdb_00008zsm", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsn", "url": "https://www.rcsb.org/structure/pdb_00008zsn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zso", "url": "https://www.rcsb.org/structure/pdb_00008zso", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsq", "url": "https://www.rcsb.org/structure/pdb_00008zsq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsr", "url": "https://www.rcsb.org/structure/pdb_00008zsr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zxz", "url": "https://www.rcsb.org/structure/pdb_00008zxz", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009buh", "url": "https://www.rcsb.org/structure/pdb_00009buh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009bwd", "url": "https://www.rcsb.org/structure/pdb_00009bwd", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009bxv", "url": "https://www.rcsb.org/structure/pdb_00009bxv", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009cd6", "url": "https://www.rcsb.org/structure/pdb_00009cd6", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009cdn", "url": "https://www.rcsb.org/structure/pdb_00009cdn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009ce2", "url": "https://www.rcsb.org/structure/pdb_00009ce2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009j6h", "url": "https://www.rcsb.org/structure/pdb_00009j6h", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009j6w", "url": "https://www.rcsb.org/structure/pdb_00009j6w", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2C", "url": "https://www.rcsb.org/structure/7V2C", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2D", "url": "https://www.rcsb.org/structure/7V2D", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2E", "url": "https://www.rcsb.org/structure/7V2E", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2F", "url": "https://www.rcsb.org/structure/7V2F", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2H", "url": "https://www.rcsb.org/structure/7V2H", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2K", "url": "https://www.rcsb.org/structure/7V2K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2R", "url": "https://www.rcsb.org/structure/7V2R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V30", "url": "https://www.rcsb.org/structure/7V30", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V31", "url": "https://www.rcsb.org/structure/7V31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V32", "url": "https://www.rcsb.org/structure/7V32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V33", "url": "https://www.rcsb.org/structure/7V33", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V3M", "url": "https://www.rcsb.org/structure/7V3M", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VBL", "url": "https://www.rcsb.org/structure/7VBL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VBP", "url": "https://www.rcsb.org/structure/7VBP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VC0", "url": "https://www.rcsb.org/structure/7VC0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VWL", "url": "https://www.rcsb.org/structure/7VWL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VXS", "url": "https://www.rcsb.org/structure/7VXS", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VY1", "url": "https://www.rcsb.org/structure/7VY1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VY9", "url": "https://www.rcsb.org/structure/7VY9", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYE", "url": "https://www.rcsb.org/structure/7VYE", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYG", "url": "https://www.rcsb.org/structure/7VYG", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYI", "url": "https://www.rcsb.org/structure/7VYI", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYS", "url": "https://www.rcsb.org/structure/7VYS", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZ8", "url": "https://www.rcsb.org/structure/7VZ8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZV", "url": "https://www.rcsb.org/structure/7VZV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZW", "url": "https://www.rcsb.org/structure/7VZW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W00", "url": "https://www.rcsb.org/structure/7W00", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W0H", "url": "https://www.rcsb.org/structure/7W0H", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W0R", "url": "https://www.rcsb.org/structure/7W0R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W0Y", "url": "https://www.rcsb.org/structure/7W0Y", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1O", "url": "https://www.rcsb.org/structure/7W1O", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1P", "url": "https://www.rcsb.org/structure/7W1P", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1T", "url": "https://www.rcsb.org/structure/7W1T", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1U", "url": "https://www.rcsb.org/structure/7W1U", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1V", "url": "https://www.rcsb.org/structure/7W1V", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1Z", "url": "https://www.rcsb.org/structure/7W1Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W20", "url": "https://www.rcsb.org/structure/7W20", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2K", "url": "https://www.rcsb.org/structure/7W2K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2L", "url": "https://www.rcsb.org/structure/7W2L", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2R", "url": "https://www.rcsb.org/structure/7W2R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2U", "url": "https://www.rcsb.org/structure/7W2U", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2Y", "url": "https://www.rcsb.org/structure/7W2Y", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W31", "url": "https://www.rcsb.org/structure/7W31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W32", "url": "https://www.rcsb.org/structure/7W32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W35", "url": "https://www.rcsb.org/structure/7W35", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4C", "url": "https://www.rcsb.org/structure/7W4C", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4D", "url": "https://www.rcsb.org/structure/7W4D", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4E", "url": "https://www.rcsb.org/structure/7W4E", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4F", "url": "https://www.rcsb.org/structure/7W4F", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4G", "url": "https://www.rcsb.org/structure/7W4G", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4J", "url": "https://www.rcsb.org/structure/7W4J", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4K", "url": "https://www.rcsb.org/structure/7W4K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4L", "url": "https://www.rcsb.org/structure/7W4L", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4M", "url": "https://www.rcsb.org/structure/7W4M", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4N", "url": "https://www.rcsb.org/structure/7W4N", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4Q", "url": "https://www.rcsb.org/structure/7W4Q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UD1", "url": "https://www.rcsb.org/structure/8UD1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEO", "url": "https://www.rcsb.org/structure/8UEO", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEP", "url": "https://www.rcsb.org/structure/8UEP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEQ", "url": "https://www.rcsb.org/structure/8UEQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UER", "url": "https://www.rcsb.org/structure/8UER", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UES", "url": "https://www.rcsb.org/structure/8UES", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UET", "url": "https://www.rcsb.org/structure/8UET", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEU", "url": "https://www.rcsb.org/structure/8UEU", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEV", "url": "https://www.rcsb.org/structure/8UEV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEW", "url": "https://www.rcsb.org/structure/8UEW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEX", "url": "https://www.rcsb.org/structure/8UEX", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEY", "url": "https://www.rcsb.org/structure/8UEY", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEZ", "url": "https://www.rcsb.org/structure/8UEZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGH", "url": "https://www.rcsb.org/structure/8UGH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGI", "url": "https://www.rcsb.org/structure/8UGI", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGJ", "url": "https://www.rcsb.org/structure/8UGJ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGN", "url": "https://www.rcsb.org/structure/8UGN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGR", "url": "https://www.rcsb.org/structure/8UGR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZO8", "url": "https://www.rcsb.org/structure/8ZO8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZOU", "url": "https://www.rcsb.org/structure/8ZOU", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZP8", "url": "https://www.rcsb.org/structure/8ZP8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSK", "url": "https://www.rcsb.org/structure/8ZSK", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSL", "url": "https://www.rcsb.org/structure/8ZSL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSM", "url": "https://www.rcsb.org/structure/8ZSM", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSN", "url": "https://www.rcsb.org/structure/8ZSN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSO", "url": "https://www.rcsb.org/structure/8ZSO", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSQ", "url": "https://www.rcsb.org/structure/8ZSQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSR", "url": "https://www.rcsb.org/structure/8ZSR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZXZ", "url": "https://www.rcsb.org/structure/8ZXZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9BUH", "url": "https://www.rcsb.org/structure/9BUH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9BWD", "url": "https://www.rcsb.org/structure/9BWD", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9BXV", "url": "https://www.rcsb.org/structure/9BXV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CD6", "url": "https://www.rcsb.org/structure/9CD6", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CDN", "url": "https://www.rcsb.org/structure/9CDN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CE2", "url": "https://www.rcsb.org/structure/9CE2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9J6H", "url": "https://www.rcsb.org/structure/9J6H", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9J6W", "url": "https://www.rcsb.org/structure/9J6W", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF07225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003361930", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003361930", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T6M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T6M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFPKYKPSRLATLPATLDPAEYDISPETRKAQAERLAIRSRLKREYLLQYNDPNRLGVIEDPALIRWTYARSANIYPNFRPTPKTSLLGALFGIGPLFFWYYVFKTDRDKKEKLIQEGKLDQTFNISY", "length": 129, "header": "tr|A0A4X1T6M0-1|A0A4X1T6M0_PIG Isoform 1 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Sus scrofa OX=9823 GN=NDUFB4 PE=1 SV=1 CANONICAL=A0A4X1T6M0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T6M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0/entry#A0A4X1T6M0-1", "sequence": { "sequence": "MSFPKYKPSRLATLPATLDPAEYDISPETRKAQAERLAIRSRLKREYLLQYNDPNRLGVIEDPALIRWTYARSANIYPNFRPTPKTSLLGALFGIGPLFFWYYVFKTDRDKKEKLIQEGKLDQTFNISY", "length": 129, "header": "tr|A0A4X1T6M0-1|A0A4X1T6M0_PIG Isoform 1 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Sus scrofa OX=9823 GN=NDUFB4 PE=1 SV=1 CANONICAL=A0A4X1T6M0-1" }, "locus": { "chromosome": "13", "start_pos": 139730429, "end_pos": 139724204, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049423.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049423.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058556.1", "url": "https://www.ensembl.org/id/ENSSSCP00000058556.1" } ] } }, { "isoform_ac": "A0A5G2QVR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0/entry#A0A5G2QVR1-1", "sequence": { "sequence": "MSFPKYKPSRLATLPATLDPAEYDISPETRKAQAERLAIRSRLKREYLLQYNDPNRLGVIEDPALIRWTYARSANIYPNFRPTPKTSLLGALFGIGPLFFWYYVFKTDRVSIRTSFWFISL", "length": 121, "header": "tr|A0A5G2QVR1-1|A0A4X1T6M0_PIG Computationally mapped isoform of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Sus scrofa OX=9823 GN=NDUFB4 PE=1 SV=2 CANONICAL=A0A4X1T6M0-1" }, "locus": { "chromosome": "13", "start_pos": 139730429, "end_pos": 139725261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068054.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068054.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069044.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069044.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "The coupling mechanism of mammalian mitochondrial complex I.", "journal": "Nat. Struct. Mol. Biol.", "date": "2022", "authors": "Gu Jinke, Liu Tianya, Guo Runyu, Zhang Laixing, Yang Maojun", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0" } ], "reference": [ { "type": "PubMed", "id": "35145322", "url": "https://glygen.org/publication/PubMed/35145322" } ] }, { "title": "High-resolution in situ structures of mammalian respiratory supercomplexes.", "journal": "Nature", "date": "2024", "authors": "Zheng Wan, Chai Pengxin, Zhu Jiapeng, Zhang Kai", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0" } ], "reference": [ { "type": "PubMed", "id": "38811722", "url": "https://glygen.org/publication/PubMed/38811722" } ] } ], "pathway": [ { "id": "ssc:100624335", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624335", "resource": "KEGG Pathway" }, { "id": "R-SSC-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-SSC-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M7T1-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "gene_name": "Ndufb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFSKYKPAPLAALPSTLDSVEYDVSPETRKAQVECMSIRAWLKREYLLQYNDPKRQTHIEDPALIRWTYARSANVYPNFRPTPKNSLLGAVAGLGPLIFWYYVIKTDRDKKERLIQEGKLDRKFSISY", "length": 129 }, "evidence": [ { "id": "A0A4X1T6M0", "url": "https://omabrowser.org/oma/group/A0A4X1T6M0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HAI5-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "gene_name": "Ndufb4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADSKYKPAPLATLPSTLDPAEYDLSPETRKAQIERLSIRARLKREYLLQYNDPKRQTHIEDPALIRWTYAKSTSVYPNFRPTPKNSLIGALAAFGPLIFWYYVFKTDRDRQEKLIQEGKLDRTFKLSY", "length": 129 }, "evidence": [ { "id": "A0A4X1T6M0", "url": "https://omabrowser.org/oma/group/A0A4X1T6M0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95168-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "gene_name": "NDUFB4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFPKYKPSSLRTLPETLDPAEYNISPETRRAQAERLAIRAQLKREYLLQYNDPNRRGLIENPALLRWAYARTINVYPNFRPTPKNSLMGALCGFGPLIFIYYIIKTERDRKEKLIQEGKLDRTFHLSY", "length": 129 }, "evidence": [ { "id": "A0A4X1T6M0", "url": "https://omabrowser.org/oma/group/A0A4X1T6M0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P48305-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "gene_name": "NDUFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSFPKYEASRLSSLPTTLDPAEYDISSETRKAQAERLAIRSRLKREYQLQYYDPSRRGVIEDPALVRWTYARSANIYPNFRPNTKTSLLGALFGIGPLVFWYYVFKTDRDRKEKLIQEGKLDRTFNISY", "length": 129 }, "evidence": [ { "id": "A0A4X1T6M0", "url": "https://omabrowser.org/oma/group/A0A4X1T6M0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CQC7-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "gene_name": "Ndufb4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGSKYKPAPLATLPSTLDPAEYDVSPETRRAQVERLSIRARLKREYLLQYNDPKRVSHIEDPALIRWTYARSANIYPNFRPTPKNSLLGAVAGFGPLIFWYYVFKTDRDRKERLIQEGKLDRKFNISY", "length": 129 }, "evidence": [ { "id": "A0A4X1T6M0", "url": "https://omabrowser.org/oma/group/A0A4X1T6M0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "respiratory electron transport chain", "id": "GO:0022904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022904", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6M0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T6W7-1", "uniprot_ac": "A0A4X1T6W7", "uniprot_id": "A0A4X1T6W7_PIG", "mass": { "chemical_mass": 26370.0, "monoisotopic_mass": 26370.0 }, "refseq": { "ac": "XP_020925964", "name": "rab-like protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925964" }, "gene_names": [ { "name": "RABL3", "type": "recommended", "evidence": [ { "id": "A0A4X1T6W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7" } ] }, { "name": "RABL3", "type": "synonym", "evidence": [ { "id": "XP_020925964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925964" } ] } ], "protein_names": [ { "name": "Rab-like protein 3", "type": "recommended", "evidence": [ { "id": "A0A4X1T6W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A4X1T6W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7/entry#names_and_taxonomy" } ] }, { "name": "rab-like protein 3", "type": "synonym", "evidence": [ { "id": "XP_020925964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925964" } ] } ], "function": [ { "annotation": "Small GTPase required for KRAS signaling regulation and modulation of cell proliferation. Regulator of KRAS prenylation, and probably prenylation of other small GTPases. Required for lymphocyte development and function. Not required for myeloid cell development. Interacts with Rab11 to promote ciliary vesicle formation at the mother centriole, thereby regulating early ciliogenesis. The GTP-binding capacity of RABL3 is essential for ciliogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6W7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7#function" }, { "database": "UniProtKB", "id": "ARBA00094278", "url": "https://www.uniprot.org/uniprotkb/ARBA00094278#function" }, { "database": "UniProtKB", "id": "A0A8D1HV24", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HV24#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6W7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RABL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7", "locus": { "chromosome": "13", "start_pos": 139652431, "end_pos": 139603454, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000035258", "url": "https://www.ensembl.org/id/ENSSSCG00000035258" } ] } } ], "crossref": [ { "id": "A0A4X1T6W7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T6W7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04102", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04102", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100624155", "url": "https://www.ncbi.nlm.nih.gov/gene/100624155", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624155", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624155", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THLICQQ", "url": "https://omabrowser.org/oma/group/THLICQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T6W7", "url": "https://www.orthodb.org/?gene=A0A4X1T6W7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24073", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24073", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08477", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08477", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020925964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925964", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T6W7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T6W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0ND00", "url": "https://www.uniprot.org/uniprotkb/A0A8D0ND00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0ND00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0ND00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1HV24", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HV24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1HV24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HV24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLDRVKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRVHDYKEGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEALNRDLVPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIHETKRHEVLTRTAFLAEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIEKRYFLRDGNQIPGFPDRKRFGGGTLKSLHYD", "length": 236, "header": "tr|A0A4X1T6W7-1|A0A4X1T6W7_PIG Isoform 1 of Rab-like protein 3 OS=Sus scrofa OX=9823 GN=RABL3 PE=3 SV=1 CANONICAL=A0A4X1T6W7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T6W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7/entry#A0A4X1T6W7-1", "sequence": { "sequence": "MASLDRVKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRVHDYKEGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEALNRDLVPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIHETKRHEVLTRTAFLAEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIEKRYFLRDGNQIPGFPDRKRFGGGTLKSLHYD", "length": 236, "header": "tr|A0A4X1T6W7-1|A0A4X1T6W7_PIG Isoform 1 of Rab-like protein 3 OS=Sus scrofa OX=9823 GN=RABL3 PE=3 SV=1 CANONICAL=A0A4X1T6W7-1" }, "locus": { "chromosome": "13", "start_pos": 139651205, "end_pos": 139609632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043074.2", "url": "https://www.ensembl.org/id/ENSSSCT00000043074.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059546.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059546.1" } ] } }, { "isoform_ac": "A0A8D0ND00-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7/entry#A0A8D0ND00-1", "sequence": { "sequence": "MASLDRVKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRVHDYKEGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEALNRDLVPTGVLVTNGIAQIHGT", "length": 135, "header": "tr|A0A8D0ND00-1|A0A4X1T6W7_PIG Computationally mapped isoform of Rab-like protein 3 OS=Sus scrofa OX=9823 GN=RABL3 PE=3 SV=1 CANONICAL=A0A4X1T6W7-1" }, "locus": { "chromosome": "13", "start_pos": 139647572, "end_pos": 139609632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090478.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090478.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074140.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074140.1" } ] } }, { "isoform_ac": "A0A8D1HV24-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7/entry#A0A8D1HV24-1", "sequence": { "sequence": "MASLDRVKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRVHDYKEGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEALNRDLVPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIHETKRHEVLTRTAFLAEDFNAEEINLVIEKRYFLRDGNQIPGFPDRKRFGGGTLKSLHYD", "length": 212, "header": "tr|A0A8D1HV24-1|A0A4X1T6W7_PIG Computationally mapped isoform of Rab-like protein 3 OS=Sus scrofa OX=9823 GN=RABL3 PE=3 SV=1 CANONICAL=A0A4X1T6W7-1" }, "locus": { "chromosome": "13", "start_pos": 139651205, "end_pos": 139609632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056524.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056524.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037094.1", "url": "https://www.ensembl.org/id/ENSSSCP00000037094.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0ND00", "url": "https://www.uniprot.org/uniprotkb/A0A8D0ND00" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624155", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624155", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I233-1", "protein_name": "Rab-like protein 3", "gene_name": "Rabl3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASLDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIRVHDYKEGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNRDLVPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIHETKRHEVSIRTAFLAEDFNAEEINLDCTNPRSSAAGSSNAVKLSRFFDKVIEKRYFCREGNQIPGFPDRKRFGGGTLKNFHYD", "length": 236 }, "evidence": [ { "id": "A0A4X1T6W7", "url": "https://omabrowser.org/oma/group/A0A4X1T6W7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6A072-1", "protein_name": "Rab-like protein 3", "gene_name": "Rabl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "NPGQKLVSPNLKISIKGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIRVHDYKEGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNRDAVPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIHETKRHEVLIRTAFLAEDFNAEEINLDCTNPRSSAAGSSNAVKLSRFFDKVIEKRYLFREGNQIPGFSDRKRFGGGTLKNFHCD", "length": 237 }, "evidence": [ { "id": "A0A4X1T6W7", "url": "https://omabrowser.org/oma/group/A0A4X1T6W7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32LJ6-1", "protein_name": "Rab-like protein 3", "gene_name": "RABL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASLDRVKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRVHDYKEGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEALNRDLVPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIHENKRHEVLTRTAFLAEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIEKRYFLRDGNQIPGFPDRKRFGGGTLKSLHYD", "length": 236 }, "evidence": [ { "id": "A0A4X1T6W7", "url": "https://omabrowser.org/oma/group/A0A4X1T6W7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6TNS7-1", "protein_name": "Rab-like protein 3", "gene_name": "rabl3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASLDRVKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRVHDYREGTPEEKAFYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEALSKDSSPTGIIVSNGDYDREQFAENAVPLLLIGTKFDQIPENKRNDVLTRTAFLSEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIEKRYFTRDPSQMQSFTDRRRFNFKSLHSD", "length": 233 }, "evidence": [ { "id": "A0A4X1T6W7", "url": "https://omabrowser.org/oma/group/A0A4X1T6W7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D4V7-1", "protein_name": "Rab-like protein 3", "gene_name": "Rabl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIRVHDYKEGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNRDAVPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIHETKRHEVLIRTAFLAEDFNAEEINLDCTNPRSSAAGSSNAVKLSRFFDKVIEKRYFFREGNQIPGFSDRKRFGGGALKNFHCD", "length": 236 }, "evidence": [ { "id": "A0A4X1T6W7", "url": "https://omabrowser.org/oma/group/A0A4X1T6W7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "natural killer cell differentiation", "id": "GO:0001779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001779", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6W7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6W7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6W7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7" } ], "pmid": "" }, { "name": "T cell differentiation in thymus", "id": "GO:0033077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033077", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6W7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7" } ], "pmid": "" }, { "name": "regulation of Ras protein signal transduction", "id": "GO:0046578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046578", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6W7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7" } ], "pmid": "" }, { "name": "positive regulation of cilium assembly", "id": "GO:0045724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045724", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6W7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6W7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6W7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T6W7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T6W7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T7C5-1", "uniprot_ac": "A0A4X1T7C5", "uniprot_id": "A0A4X1T7C5_PIG", "mass": { "chemical_mass": 11697.0, "monoisotopic_mass": 11697.0 }, "refseq": { "ac": "NP_001177154", "name": "anaphase-promoting complex subunit 16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177154" }, "gene_names": [ { "name": "ANAPC16", "type": "recommended", "evidence": [ { "id": "A0A4X1T7C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5" } ] }, { "name": "ANAPC16", "type": "synonym", "evidence": [ { "id": "NP_001177154", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177154" } ] } ], "protein_names": [ { "name": "Anaphase-promoting complex subunit 16", "type": "recommended", "evidence": [ { "id": "A0A4X1T7C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5/entry#names_and_taxonomy" } ] }, { "name": "Cyclosome subunit 16", "type": "synonym", "evidence": [ { "id": "A0A4X1T7C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5/entry#names_and_taxonomy" } ] }, { "name": "anaphase-promoting complex subunit 16", "type": "synonym", "evidence": [ { "id": "NP_001177154", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177154" } ] } ], "function": [ { "annotation": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5#function" }, { "database": "UniProtKB", "id": "ARBA00045696", "url": "https://www.uniprot.org/uniprotkb/ARBA00045696#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ANAPC16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5", "locus": { "chromosome": "14", "start_pos": 75093074, "end_pos": 75082740, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000061761", "url": "https://www.ensembl.org/id/ENSSSCG00000061761" } ] } } ], "crossref": [ { "id": "100155019", "url": "https://www.ncbi.nlm.nih.gov/gene/100155019", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155019", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155019", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GASRRCH", "url": "https://omabrowser.org/oma/group/GASRRCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T7C5", "url": "https://www.orthodb.org/?gene=A0A4X1T7C5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31564", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31564", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31564:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31564:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174048", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174048", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174084", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174084", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174154", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174154", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174178", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174184", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174184", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-176407", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-176408", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-176409", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-176412", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176412", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-179409", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-179409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2559582", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559582", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68867", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68867", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-69017", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69017", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001177154", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177154", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T7C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASSSSSSAGGVSGSSVTGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLASLVEELEADEWRFKPIEQLLGFTPSSG", "length": 110, "header": "tr|A0A4X1T7C5-1|A0A4X1T7C5_PIG Isoform 1 of Anaphase-promoting complex subunit 16 OS=Sus scrofa OX=9823 GN=ANAPC16 PE=3 SV=1 CANONICAL=A0A4X1T7C5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T7C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5/entry#A0A4X1T7C5-1", "sequence": { "sequence": "MAASSSSSSAGGVSGSSVTGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLASLVEELEADEWRFKPIEQLLGFTPSSG", "length": 110, "header": "tr|A0A4X1T7C5-1|A0A4X1T7C5_PIG Isoform 1 of Anaphase-promoting complex subunit 16 OS=Sus scrofa OX=9823 GN=ANAPC16 PE=3 SV=1 CANONICAL=A0A4X1T7C5-1" }, "locus": { "chromosome": "14", "start_pos": 75092327, "end_pos": 75085804, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104041.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104041.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079289.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079289.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155019", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155019", "resource": "KEGG Pathway" }, { "id": "R-SSC-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-SSC-174048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174048", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Cyclin B" }, { "id": "R-SSC-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-SSC-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-SSC-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-SSC-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-SSC-176407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176407", "resource": "Reactome", "description": "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" }, { "id": "R-SSC-176408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176408", "resource": "Reactome", "description": "Regulation of APC/C activators between G1/S and early anaphase" }, { "id": "R-SSC-176409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176409", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of mitotic proteins" }, { "id": "R-SSC-176412", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176412", "resource": "Reactome", "description": "Phosphorylation of the APC/C" }, { "id": "R-SSC-179409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-179409", "resource": "Reactome", "description": "APC-Cdc20 mediated degradation of Nek2A" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2559582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559582", "resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-SSC-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-SSC-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" } ], "orthologs": [ { "uniprot_canonical_ac": "Q58DR0-1", "protein_name": "Anaphase-promoting complex subunit 16", "gene_name": "ANAPC16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAASSSSSSAGGVSGSSVAGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG", "length": 110 }, "evidence": [ { "id": "A0A4X1T7C5", "url": "https://omabrowser.org/oma/group/A0A4X1T7C5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96DE5-1", "protein_name": "Anaphase-promoting complex subunit 16", "gene_name": "ANAPC16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASSSSSSAGGVSGSSVTGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG", "length": 110 }, "evidence": [ { "id": "A0A4X1T7C5", "url": "https://omabrowser.org/oma/group/A0A4X1T7C5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CPV2-1", "protein_name": "Anaphase-promoting complex subunit 16", "gene_name": "Anapc16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASSSSSSAGGVSGSSVTGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG", "length": 110 }, "evidence": [ { "id": "A0A4X1T7C5", "url": "https://omabrowser.org/oma/group/A0A4X1T7C5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5" } ], "pmid": "" }, { "name": "protein branched polyubiquitination", "id": "GO:0141198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141198", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T7K7-1", "uniprot_ac": "A0A4X1T7K7", "uniprot_id": "A0A4X1T7K7_PIG", "mass": { "chemical_mass": 71385.0, "monoisotopic_mass": 71385.0 }, "refseq": {}, "gene_names": [ { "name": "PLS1", "type": "recommended", "evidence": [ { "id": "A0A4X1T7K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ] } ], "protein_names": [ { "name": "Plastin 1", "type": "synonym", "evidence": [ { "id": "A0A4X1T7K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PLS1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7", "locus": { "chromosome": "13", "start_pos": 83434128, "end_pos": 83308007, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011680", "url": "https://www.ensembl.org/id/ENSSSCG00000011680" } ] } } ], "crossref": [ { "id": "A0A4X1T7K7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T7K7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21323", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21323", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21326", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21326", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21329", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21329", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21332", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21332", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19961", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19961", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19961:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19961:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T7K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1XLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XLJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1XLJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XLJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILTVADNNKDGKISFEEFVSLMQELKSKDISKTFRKIINKKEGITAIGGTSSISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLLPMNPNDESLFKSLADGILLCKMINLSEPDTIDERAINKKKLTPFTISENLNLALNSASAIGCTVVNIGAQDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLKEGEDLEELLKLSPEELLLRWVNYHLTNAGWRTISNFSQDIKDSRAYFHLLNQIAPKGDRDDGPAIDIDLSGFNEQNDLKRAEFMLREADKLGCRQFVTPADVVSGNPKLNLAFVANLFNTYPSLHKPDNNNIDINLLEDLTPPNVGESKEERTFRNWMNSLGVSPYINHLYSDLADALVIFQLYEMIRVPVDWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLNEGNSTLTLALVWQLMRRYTLNVLSDLGEGEKVNDAIIIEWVNQTLKSANKNTFISSFKDKAISTSLPVLDLIDAIAPNAIRQEMIKREDLSDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKGLNKIK", "length": 637, "header": "tr|A0A4X1T7K7-1|A0A4X1T7K7_PIG Isoform 1 of Plastin 1 OS=Sus scrofa OX=9823 GN=PLS1 PE=1 SV=1 CANONICAL=A0A4X1T7K7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T7K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7/entry#A0A4X1T7K7-1", "sequence": { "sequence": "MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILTVADNNKDGKISFEEFVSLMQELKSKDISKTFRKIINKKEGITAIGGTSSISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLLPMNPNDESLFKSLADGILLCKMINLSEPDTIDERAINKKKLTPFTISENLNLALNSASAIGCTVVNIGAQDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLKEGEDLEELLKLSPEELLLRWVNYHLTNAGWRTISNFSQDIKDSRAYFHLLNQIAPKGDRDDGPAIDIDLSGFNEQNDLKRAEFMLREADKLGCRQFVTPADVVSGNPKLNLAFVANLFNTYPSLHKPDNNNIDINLLEDLTPPNVGESKEERTFRNWMNSLGVSPYINHLYSDLADALVIFQLYEMIRVPVDWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLNEGNSTLTLALVWQLMRRYTLNVLSDLGEGEKVNDAIIIEWVNQTLKSANKNTFISSFKDKAISTSLPVLDLIDAIAPNAIRQEMIKREDLSDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKGLNKIK", "length": 637, "header": "tr|A0A4X1T7K7-1|A0A4X1T7K7_PIG Isoform 1 of Plastin 1 OS=Sus scrofa OX=9823 GN=PLS1 PE=1 SV=1 CANONICAL=A0A4X1T7K7-1" }, "locus": { "chromosome": "13", "start_pos": 83432170, "end_pos": 83377607, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052898.2", "url": "https://www.ensembl.org/id/ENSSSCT00000052898.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055778.2", "url": "https://www.ensembl.org/id/ENSSSCP00000055778.2" } ] } }, { "isoform_ac": "A0A8D1XLJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7/entry#A0A8D1XLJ1-1", "sequence": { "sequence": "MENSTTTISREELEELQEAFNKIVADNNKDGKISFEEFVSLMQELKSKDISKTFRKIINKKEGITAIGGTSSISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLLPMNPNDESLFKSLADGILLCKMINLSEPDTIDERAINKKKLTPFTISENLNLALNSASAIGCTVVNIGAQDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLKEGEDLEELLKLSPEELLLRWVNYHLTNAGWRTISNFSQDIKDSRAYFHLLNQIAPKGDRDDGPAIDIDLSGFNEQNDLKRAEFMLREADKLGCRQFVTPADVVSGNPKLNLAFVANLFNTYPSLHKPDNNNIDINLLEGESKEERTFRNWMNSLGVSPYINHLYSDLADALVIFQLYEMIRVPVDWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLNEGNSTLTLALVWQLMRRYTLNVLSDLGEGEKVNDAIIIEWVNQTLKSANKNTFISSFKDKAISTSLPVLDLIDAIAPNAIRQEMIKREDLSDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKGLNKIK", "length": 592, "header": "tr|A0A8D1XLJ1-1|A0A4X1T7K7_PIG Computationally mapped isoform of Plastin 1 OS=Sus scrofa OX=9823 GN=PLS1 PE=1 SV=1 CANONICAL=A0A4X1T7K7-1" }, "locus": { "chromosome": "13", "start_pos": 83432170, "end_pos": 83377607, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057689.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057689.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045916.2", "url": "https://www.ensembl.org/id/ENSSSCP00000045916.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 108, "start_aa": "Thr", "end_pos": 108, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr108", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 353, "start_aa": "Thr", "end_pos": 353, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr353", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1XLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XLJ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "intestinal D-glucose absorption", "id": "GO:0001951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001951", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "positive regulation of protein localization to plasma membrane", "id": "GO:1903078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903078", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "actin filament network formation", "id": "GO:0051639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051639", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "positive regulation of multicellular organism growth", "id": "GO:0040018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040018", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "regulation of microvillus length", "id": "GO:0032532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032532", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "auditory receptor cell stereocilium organization", "id": "GO:0060088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060088", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "vestibular receptor cell stereocilium organization", "id": "GO:0060121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060121", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "actin filament bundle", "id": "GO:0032432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032432", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "terminal web", "id": "GO:1990357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7K7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T7K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 238, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T7K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7K7" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 46, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 108, 353 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 535, "end_pos": 537 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T7U4-1", "uniprot_ac": "A0A4X1T7U4", "uniprot_id": "A0A4X1T7U4_PIG", "mass": { "chemical_mass": 25026.0, "monoisotopic_mass": 25026.0 }, "refseq": { "ac": "NP_001230381", "name": "DNA damage-inducible transcript 4 protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230381" }, "gene_names": [ { "name": "DDIT4", "type": "recommended", "evidence": [ { "id": "A0A4X1T7U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4" } ] }, { "name": "DDIT4", "type": "synonym", "evidence": [ { "id": "NP_001230381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230381" } ] } ], "protein_names": [ { "name": "DNA damage-inducible transcript 4 protein", "type": "recommended", "evidence": [ { "id": "A0A4X1T7U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4/entry#names_and_taxonomy" } ] }, { "name": "DNA damage-inducible transcript 4 protein", "type": "synonym", "evidence": [ { "id": "NP_001230381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230381" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7U4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DDIT4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4", "locus": { "chromosome": "14", "start_pos": 75119902, "end_pos": 75117710, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031888", "url": "https://www.ensembl.org/id/ENSSSCG00000031888" } ] } } ], "crossref": [ { "id": "A0A4X1T7U4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T7U4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100153821", "url": "https://www.ncbi.nlm.nih.gov/gene/100153821", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012918", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012918", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153821", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153821", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPGLWER", "url": "https://omabrowser.org/oma/group/MPGLWER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T7U4", "url": "https://www.orthodb.org/?gene=A0A4X1T7U4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12478", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12478", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12478:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12478:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07809", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07809", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230381", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230381", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T7U4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T7U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNLWDRFSSSSSSSSSSLSRTPTPNQPPRSAWGSAAREEGLGRCASLESSDCESLDSSNSGFGPEEDSAYLDGVSLPDFELLSDPEDEHLCASLMQLLQESLAQARLGSRRPARLLMPGQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVGQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLFSSANSPFVPGFSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231, "header": "tr|A0A4X1T7U4-1|A0A4X1T7U4_PIG Isoform 1 of DNA damage-inducible transcript 4 protein OS=Sus scrofa OX=9823 GN=DDIT4 PE=3 SV=1 CANONICAL=A0A4X1T7U4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T7U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4/entry#A0A4X1T7U4-1", "sequence": { "sequence": "MPNLWDRFSSSSSSSSSSLSRTPTPNQPPRSAWGSAAREEGLGRCASLESSDCESLDSSNSGFGPEEDSAYLDGVSLPDFELLSDPEDEHLCASLMQLLQESLAQARLGSRRPARLLMPGQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVGQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLFSSANSPFVPGFSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231, "header": "tr|A0A4X1T7U4-1|A0A4X1T7U4_PIG Isoform 1 of DNA damage-inducible transcript 4 protein OS=Sus scrofa OX=9823 GN=DDIT4 PE=3 SV=1 CANONICAL=A0A4X1T7U4-1" }, "locus": { "chromosome": "14", "start_pos": 75119020, "end_pos": 75118045, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041250.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041250.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041159.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041159.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7U4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153821", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153821", "resource": "KEGG Pathway" }, { "id": "R-SSC-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZK41-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "DDIT4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPGLWERLGDGERGSLESSDCESLGSASGSEGDPERTSLPDLELLHDPEDELLSARLLELVQAALGSAPLGSRRRSRLLMPAQLAAQLRSELLRLACSEPCGLRGALLDLCVEHGKACHDVGRIAADPAVVPTFQLTLVLRLDSRLWPKIQGLLASAPALSPAFGQSLKLSTGFRVMKKKLYSSEQLLVEEC", "length": 192 }, "evidence": [ { "id": "A0A4X1T7U4", "url": "https://omabrowser.org/oma/group/A0A4X1T7U4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q08E62-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "DDIT4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSLSRTPTPNQPPRSAWGSAAREEGLGRCGSLESSDCESLDSSNSGFGPEEDSAYLDGVSLPDFELLSDPEDEHLCASLMQLLQESLAQARLGSRRPARLLMPGQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVGQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLFSSANSPFVPGFSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 229 }, "evidence": [ { "id": "A0A4X1T7U4", "url": "https://omabrowser.org/oma/group/A0A4X1T7U4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VHZ9-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSRTPAADRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLLSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 229 }, "evidence": [ { "id": "A0A4X1T7U4", "url": "https://omabrowser.org/oma/group/A0A4X1T7U4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D3F7-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSRTPAADRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 229 }, "evidence": [ { "id": "A0A4X1T7U4", "url": "https://omabrowser.org/oma/group/A0A4X1T7U4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NX09-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "DDIT4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSLWDRFSSSSTSSSPSSLPRTPTPDRPPRSAWGSATREEGFDRSTSLESSDCESLDSSNSGFGPEEDTAYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLAQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVGQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLFSSANSPFLPGFSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 232 }, "evidence": [ { "id": "A0A4X1T7U4", "url": "https://omabrowser.org/oma/group/A0A4X1T7U4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VTH4-1", "protein_name": "Protein scylla", "gene_name": "scyl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKMDVIAREQIIYGSLQGSNKNKDWTSRLPPPSAYTLDLMSKKAKTTTGGSSNGSNATATSTTTSTSSSIKHKQPAGSSNNNVGQSQSKKTKPSGSYNSNSNYYYYAADEEEGGSADYALSNYDKKAVEELSLRLLDELRAAKSRHLTCTEVSLPCDLTPSVAREIIRVSEKEPRGIRGCTIYIEFEDEPKNSRRIASIKVDSDTVSTFEVYLTLRQDHRGWTSLLPQFMKSLARTITISPEYTITKNKLYSADGLGARRSYSFGSHAHRPSAAIATPTN", "length": 280 }, "evidence": [ { "id": "A0A4X1T7U4", "url": "https://omabrowser.org/oma/group/A0A4X1T7U4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7U4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7U4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7U4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7U4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7U4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "id": "GO:0042771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042771", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7U4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7U4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "14-3-3 protein binding", "id": "GO:0071889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071889", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T7U4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7U4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T869-1", "uniprot_ac": "A0A4X1T869", "uniprot_id": "A0A4X1T869_PIG", "mass": { "chemical_mass": 34362.0, "monoisotopic_mass": 34362.0 }, "refseq": { "ac": "XP_003131903", "name": "olfactory receptor 139", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131903" }, "gene_names": [ { "name": "LOC100517239", "type": "recommended", "evidence": [ { "id": "A0A4X1T869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869" } ] }, { "name": "LOC100517239", "type": "synonym", "evidence": [ { "id": "XP_003131903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131903" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1T869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 139", "type": "synonym", "evidence": [ { "id": "XP_003131903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131903" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T869", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T869", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100517239", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869", "locus": {} } ], "crossref": [ { "id": "A0A4X1T869", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T869", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15233", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15233", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100517239", "url": "https://www.ncbi.nlm.nih.gov/gene/100517239", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517239", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517239", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGVFPMI", "url": "https://omabrowser.org/oma/group/MGVFPMI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003131903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131903", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T869", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T869-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELGARGNRTAVTEFILLGLTENIRLQAILFTVFLFAYVITVGGNFSILAAIFVEPKLHTPMYYFLGNLSLLDIGCITVTVPPMLACLLTHQCRVPYAACISQLFFFHLLAGVDCHLLTAMAYDRYLAICQPLTYSTRMSREVQAALVGICCTISLINALTHTVAVSVLDFCGPNVVNHFYCDLPPLFQLSCSSIHLNGQLLFAGATFMGVVPMILISVSYTHVAAAVLRIRSAEGRKKAFSTCGSHLTVVCIFYGTGFFSYMRLGSVSASDKDKGIGILNTILSPMLNPVIYSLRNPDVQGALKRVLTGKRPPE", "length": 315, "header": "tr|A0A4X1T869-1|A0A4X1T869_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100517239 PE=3 SV=1 CANONICAL=A0A4X1T869-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T869-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869/entry#A0A4X1T869-1", "sequence": { "sequence": "MELGARGNRTAVTEFILLGLTENIRLQAILFTVFLFAYVITVGGNFSILAAIFVEPKLHTPMYYFLGNLSLLDIGCITVTVPPMLACLLTHQCRVPYAACISQLFFFHLLAGVDCHLLTAMAYDRYLAICQPLTYSTRMSREVQAALVGICCTISLINALTHTVAVSVLDFCGPNVVNHFYCDLPPLFQLSCSSIHLNGQLLFAGATFMGVVPMILISVSYTHVAAAVLRIRSAEGRKKAFSTCGSHLTVVCIFYGTGFFSYMRLGSVSASDKDKGIGILNTILSPMLNPVIYSLRNPDVQGALKRVLTGKRPPE", "length": 315, "header": "tr|A0A4X1T869-1|A0A4X1T869_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100517239 PE=3 SV=1 CANONICAL=A0A4X1T869-1" }, "locus": { "chromosome": "12", "start_pos": 49429798, "end_pos": 49428854, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097246.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097246.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081082.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081082.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T869", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517239", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517239", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LRC1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100766158", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPGVWGNRTTVTEFVLLGLTGNVRLQLILFVVFFFAYILTVGGNFSILAAIFVEPKLHTPMYYFLGTLSLLDIGCINVTVPPMLVCLLAHQCRVPYTACISQLFFFHLLAGVDCHLLTAMAYDRYLAICQPLTYSIRMSREVQVILVGICCTVSFINALTHTVAVSVLDFCGPNVVNHFYCDLPPLFQLSCSSIHLNGQLLFVGATFMGVVPMILISVSYANVAAAVLRIRSAEGRKKAFSTCGSHLTVVCIFYGTGFFSYMRLGSVSASDKDKGIGIFNTILNPMLNPVIYSLRNPDVQGALKRVLTGKRHLV", "length": 315 }, "evidence": [ { "id": "A0A4X1T869", "url": "https://omabrowser.org/oma/group/A0A4X1T869/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MI00-1", "protein_name": "Olfactory receptor", "gene_name": "OR3A10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPGAWGNKTVVTEFILLGLTKNIELQSILFAIFLFAYVITVGGNLSILAAIFVEPKLHTPMYYFLGNLSLLDIGCITVTIPPMLACLLTHQCRVPYAACISQLFFFHLLAGVDCHLLTAMAYDRYLAICQPLTYSIRMSRDVQGALVAVCCSISFINALTHTVAVSVLDFCGPNVVNHFYCDLPPLFQLSCSSIHLNGQLLFVGATFMGVVPMVFISVSYAHVAAAVLRICSAEGRKKAFSTCGSHLTVVCIFYGTGFFSYMRLGSVSASDKDKGIGILNTVISPMLNPLIYSLRNPDVQGALKRLLTGKRPPE", "length": 315 }, "evidence": [ { "id": "A0A4X1T869", "url": "https://omabrowser.org/oma/group/A0A4X1T869/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q60891-1", "protein_name": "Olfactory receptor 3A10", "gene_name": "Or3a10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGAWGNRTAVTDFILLGLTGNVRLQPILFVVFFFAYIVTVGGNLSILAAIFVEPKLHTPMYYFLGNLSLLDIGCISVTVPPMLVCLLAHECRVPYAACISQLFFFHLLAGVDCHLLTAMAYDRYLAICQPLTYSTRMSREVQGTLVGICCTVSFINALTHTVAVSVLDFCGPNVVNHFYCDLPPLFQLSCSSIYLNGQLLFVGATFMGVVPMILISVSYAHVAAAVLRIRSTEGRKKAFSTCGSHLTVVCIFYGTGFFSYMRLGSVSASDKDKGIGILNTILSPMLNPLIYSLRNPDVQGALKRVLTGKRYPV", "length": 315 }, "evidence": [ { "id": "A0A4X1T869", "url": "https://omabrowser.org/oma/group/A0A4X1T869/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T869", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T869", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T869", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T869", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T869" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 293, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 }, { "start_pos": 68, "end_pos": 70 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T9A9-1", "uniprot_ac": "A0A4X1T9A9", "uniprot_id": "A0A4X1T9A9_PIG", "mass": { "chemical_mass": 22123.0, "monoisotopic_mass": 22123.0 }, "refseq": {}, "gene_names": [ { "name": "VBP1", "type": "recommended", "evidence": [ { "id": "A0A4X1T9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9" } ] } ], "protein_names": [ { "name": "Prefoldin subunit 3", "type": "recommended", "evidence": [ { "id": "A0A4X1T9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8E4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8E4#function" }, { "database": "UniProtKB", "id": "PIRNR016396", "url": "https://www.uniprot.org/uniprotkb/PIRNR016396#function" }, { "database": "UniProtKB", "id": "ARBA00024667", "url": "https://www.uniprot.org/uniprotkb/ARBA00024667#function" }, { "database": "UniProtKB", "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9#function" }, { "database": "UniProtKB", "id": "A0A4X1T8S9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "VBP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9", "locus": { "chromosome": "X", "start_pos": 125506771, "end_pos": 125480808, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012811", "url": "https://www.ensembl.org/id/ENSSSCG00000012811" } ] } } ], "crossref": [ { "id": "A0A4X1T9A9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T9A9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012811", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012811", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23156", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23156", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100514622", "url": "https://www.ncbi.nlm.nih.gov/gene/100514622", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YNWDVAQ", "url": "https://omabrowser.org/oma/group/YNWDVAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T8E4", "url": "https://www.orthodb.org/?gene=A0A4X1T8E4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12409:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12409:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02996", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02996", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1T8E4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8E4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8S9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8T4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T9A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMU1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPQPMFSTPLGFSTGPPSAPSTRHKEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTSSLETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA", "length": 192, "header": "tr|A0A4X1T9A9-1|A0A4X1T9A9_PIG Isoform 1 of Prefoldin subunit 3 OS=Sus scrofa OX=9823 GN=VBP1 PE=1 SV=1 CANONICAL=A0A4X1T9A9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T8E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9/entry#A0A4X1T8E4-1", "sequence": { "sequence": "MKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTSSLETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA", "length": 160, "header": "tr|A0A4X1T8E4-1|A0A4X1T9A9_PIG Computationally mapped isoform of Prefoldin subunit 3 OS=Sus scrofa OX=9823 GN=VBP1 PE=1 SV=1 CANONICAL=A0A4X1T9A9-1" }, "locus": { "chromosome": "X", "start_pos": 125505783, "end_pos": 125489225, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081953.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081953.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059957.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059957.1" } ] } }, { "isoform_ac": "A0A4X1T8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9/entry#A0A4X1T8S9-1", "sequence": { "sequence": "MRRLTREGRACGCERANHSPPAAGSPRGSLSRARFPKMADAKDGCGLGEVAAGNGRRLHLGIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTSSLETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA", "length": 234, "header": "tr|A0A4X1T8S9-1|A0A4X1T8S9_PIG Computationally mapped isoform of Prefoldin subunit 3 OS=Sus scrofa OX=9823 GN=VBP1 PE=1 SV=1 CANONICAL=A0A4X1T9A9-1" }, "locus": { "chromosome": "X", "start_pos": 125505783, "end_pos": 125485256, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035199.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035199.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029596.2", "url": "https://www.ensembl.org/id/ENSSSCP00000029596.2" } ] } }, { "isoform_ac": "A0A4X1T8T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9/entry#A0A4X1T8T4-1", "sequence": { "sequence": "MRRLTREGRACGCERANHSPPAAGSPRGSLSRARFPKMADAKDGCGLGEVAAGNGRRLHLGIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA", "length": 201, "header": "tr|A0A4X1T8T4-1|A0A4X1T8T4_PIG Computationally mapped isoform of VHL binding protein 1 OS=Sus scrofa OX=9823 GN=VBP1 PE=1 SV=1 CANONICAL=A0A4X1T9A9-1" }, "locus": { "chromosome": "X", "start_pos": 125505783, "end_pos": 125485256, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014004.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014004.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013620.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013620.3" } ] } }, { "isoform_ac": "A0A4X1T9A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9/entry#A0A4X1T9A9-1", "sequence": { "sequence": "MTPQPMFSTPLGFSTGPPSAPSTRHKEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTSSLETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA", "length": 192, "header": "tr|A0A4X1T9A9-1|A0A4X1T9A9_PIG Isoform 1 of Prefoldin subunit 3 OS=Sus scrofa OX=9823 GN=VBP1 PE=1 SV=1 CANONICAL=A0A4X1T9A9-1" }, "locus": { "chromosome": "X", "start_pos": 125505783, "end_pos": 125480838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033410.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033410.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028404.3", "url": "https://www.ensembl.org/id/ENSSSCP00000028404.3" } ] } }, { "isoform_ac": "A0A5G2QMU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9/entry#A0A5G2QMU1-1", "sequence": { "sequence": "MRRLTREGRACGCERANHSPPAAGSPRGSLSRARFPKMADAKDGCGLGEVAAGNGRRLHLGIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLQMQLGSYIAVNFHILQVWPLKKKKTSRFASPCFNANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA", "length": 214, "header": "tr|A0A5G2QMU1-1|A0A4X1T9A9_PIG Computationally mapped isoform of Prefoldin subunit 3 OS=Sus scrofa OX=9823 GN=VBP1 PE=1 SV=1 CANONICAL=A0A4X1T9A9-1" }, "locus": { "chromosome": "X", "start_pos": 125505783, "end_pos": 125485256, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085959.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085959.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059631.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059631.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QMU1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMU1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A061HZ44-1", "protein_name": "Prefoldin subunit 3", "gene_name": "Vbp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAAQDGCGLDSAAGNGRRIHLGIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA", "length": 196 }, "evidence": [ { "id": "A0A4X1T9A9", "url": "https://omabrowser.org/oma/group/A0A4X1T9A9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P48363-1", "protein_name": "Prefoldin subunit 3", "gene_name": "PAC10", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDTLFNSTEKNARGIPQAPFIENVNEIIKDPSDFELCFNKFQERLSKYKFMQESKLATIKQLKTRIPDLENTLKICQSLRNHSDEGDESDEPILLHYQLNDTLYTKAQVDIPEDRADLKVGLWLGADVMLEYPIDEAIELLKKKLADSEQSLTVSTEDVEFLRENITTMEVNCARLYNWDVQRRQDLKQAQEGTKNLKI", "length": 199 }, "evidence": [ { "id": "A0A4X1T9A9", "url": "https://omabrowser.org/oma/group/A0A4X1T9A9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P61758-1", "protein_name": "Prefoldin subunit 3", "gene_name": "VBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVKDSCGKGEMATGNGRRLHLGIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA", "length": 197 }, "evidence": [ { "id": "A0A4X1T9A9", "url": "https://omabrowser.org/oma/group/A0A4X1T9A9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61759-1", "protein_name": "Prefoldin subunit 3", "gene_name": "Vbp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAKDGCGLETAAGNGRRLHLGIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA", "length": 196 }, "evidence": [ { "id": "A0A4X1T9A9", "url": "https://omabrowser.org/oma/group/A0A4X1T9A9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VGP6-1", "protein_name": "Prefoldin subunit 3", "gene_name": "mgr", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTGIMDSVEMPKLPENQKTFAGIPEAVFLEEIDTFMSQPENENCEKVLQRLDEQHGKYRFMACNLEARRRKLKSQIPDLERSLEMVNVLRKEDEERETQFLLSDQVFIKTLVPPTKTVYLWLGASVMLEYPLDEAEALLNQNITSAVGNLKSVEHDQDFLRDQITTTEVNMARVYNWGVKKRQAATKTTATTPS", "length": 194 }, "evidence": [ { "id": "A0A4X1T9A9", "url": "https://omabrowser.org/oma/group/A0A4X1T9A9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9" } ], "pmid": "" }, { "name": "prefoldin complex", "id": "GO:0016272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016272", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9" } ], "pmid": "" }, { "name": "tubulin complex assembly", "id": "GO:0007021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007021", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9" } ], "pmid": "" }, { "name": "negative regulation of amyloid fibril formation", "id": "GO:1905907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905907", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9" } ], "pmid": "" }, { "name": "microtubule-based process", "id": "GO:0007017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007017", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9" } ], "pmid": "" }, { "name": "amyloid-beta binding", "id": "GO:0001540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001540", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9A9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 38, "end_pos": 40 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T8G7-1", "uniprot_ac": "A0A4X1T8G7", "uniprot_id": "A0A4X1T8G7_PIG", "mass": { "chemical_mass": 51158.0, "monoisotopic_mass": 51158.0 }, "refseq": { "ac": "XP_005658004", "name": "eukaryotic translation initiation factor 2 subunit 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005658004" }, "gene_names": [ { "name": "LOC100624149", "type": "synonym", "evidence": [ { "id": "XP_005658004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005658004" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 2 subunit 3", "type": "recommended", "evidence": [ { "id": "A0A4X1T8G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.3", "type": "synonym", "evidence": [ { "id": "A0A4X1T8G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7/entry#names_and_taxonomy" } ] }, { "name": "Eukaryotic translation initiation factor 2 subunit gamma", "type": "synonym", "evidence": [ { "id": "A0A4X1T8G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7/entry#names_and_taxonomy" } ] }, { "name": "eukaryotic translation initiation factor 2 subunit 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005658004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005658004" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8G7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7", "locus": {} } ], "crossref": [ { "id": "A0A4X1T8G7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T8G7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01888", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01888", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03688", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03688", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15490", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15490", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100624149", "url": "https://www.ncbi.nlm.nih.gov/gene/100624149", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624149", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624149", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ILCEYIT", "url": "https://omabrowser.org/oma/group/ILCEYIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T8G7", "url": "https://www.orthodb.org/?gene=A0A4X1T8G7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42854:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42854:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09173", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09173", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005658004", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005658004", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T8G7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGEAGVTLGQPHLSRQDLTTLDVTRLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDASCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPLRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDCEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "length": 472, "header": "tr|A0A4X1T8G7-1|A0A4X1T8G7_PIG Isoform 1 of Eukaryotic translation initiation factor 2 subunit 3 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1T8G7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T8G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7/entry#A0A4X1T8G7-1", "sequence": { "sequence": "MAAGEAGVTLGQPHLSRQDLTTLDVTRLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDASCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPLRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDCEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "length": 472, "header": "tr|A0A4X1T8G7-1|A0A4X1T8G7_PIG Isoform 1 of Eukaryotic translation initiation factor 2 subunit 3 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1T8G7-1" }, "locus": { "chromosome": "Y", "start_pos": 9847423, "end_pos": 9827728, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013322.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013322.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012965.2", "url": "https://www.ensembl.org/id/ENSSSCP00000012965.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "ssc:100624149", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624149", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "C9WPN6-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3, Y-linked", "gene_name": "Eif2s3y", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGEAGVTLGQPHLSRQDLATLDVTKLTPLSHEIISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDSSCPRPECYRSCGSSTPDEFPSDIPGIKGNFRLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPLRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTIDDE", "length": 472 }, "evidence": [ { "id": "A0A4X1T8G7", "url": "https://omabrowser.org/oma/group/A0A4X1T8G7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Z0N2-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3, Y-linked", "gene_name": "Eif2s3y", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGGEAGVTLGQPHLSRQDLATLDVTKLTPLSREIISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDSSCPRPECYRSCGSSTPDEFPSDIPGTKGNFRLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPLRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDGEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTIDDE", "length": 472 }, "evidence": [ { "id": "A0A4X1T8G7", "url": "https://omabrowser.org/oma/group/A0A4X1T8G7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8G7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8G7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8G7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8G7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8G7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "eukaryotic translation initiation factor 2 complex", "id": "GO:0005850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005850", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8G7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8G7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A4X1T8U5-1", "uniprot_ac": "A0A4X1T8U5", "uniprot_id": "A0A4X1T8U5_PIG", "mass": { "chemical_mass": 71320.0, "monoisotopic_mass": 71320.0 }, "refseq": { "ac": "XP_020945683", "name": "potassium voltage-gated channel subfamily D member 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945683" }, "gene_names": [ { "name": "KCND3", "type": "recommended", "evidence": [ { "id": "A0A4X1T8U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ] }, { "name": "KCND3", "type": "synonym", "evidence": [ { "id": "XP_020945683", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945683" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel subfamily D member 3", "type": "synonym", "evidence": [ { "id": "A0A4X1T8U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5/entry#names_and_taxonomy" } ] }, { "name": "potassium voltage-gated channel subfamily D member 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020945683", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945683" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KCND3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5", "locus": { "chromosome": "4", "start_pos": 108621510, "end_pos": 108246237, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026680", "url": "https://www.ensembl.org/id/ENSSSCG00000026680" } ] } } ], "crossref": [ { "id": "A0A4X1T8U5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T8U5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18419", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18419", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100037946", "url": "https://www.ncbi.nlm.nih.gov/gene/100037946", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003975", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003975", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100037946", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100037946", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T8H8", "url": "https://www.orthodb.org/?gene=A0A4X1T8H8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF182", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF182", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11601", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11601", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11879", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11879", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5576894", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576894", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020945683", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945683", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T8H8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8H8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELMGTPEEEHVGKATSLIESQHHHLLHCLEKTTNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHPGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDGLRPNCKSSQITTAIISIPTPPALTPEGESRPPAASPGPNTNIPSIASNVVKVSAL", "length": 636, "header": "tr|A0A4X1T8U5-1|A0A4X1T8U5_PIG Isoform 1 of Potassium voltage-gated channel subfamily D member 3 OS=Sus scrofa OX=9823 GN=KCND3 PE=4 SV=1 CANONICAL=A0A4X1T8U5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T8H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5/entry#A0A4X1T8H8-1", "sequence": { "sequence": "MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELMGTPEEEHVGKATSLIESQHHHLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHPGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDGLRPNCKSSQITTAIISIPTPPALTPEGESRPPAASPGPNTNIPSIASNVVKVSAL", "length": 655, "header": "tr|A0A4X1T8H8-1|A0A4X1T8U5_PIG Computationally mapped isoform of Potassium voltage-gated channel subfamily D member 3 OS=Sus scrofa OX=9823 GN=KCND3 PE=4 SV=1 CANONICAL=A0A4X1T8U5-1" }, "locus": { "chromosome": "4", "start_pos": 108616193, "end_pos": 108401895, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007428.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007428.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007233.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007233.4" } ] } }, { "isoform_ac": "A0A4X1T8U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5/entry#A0A4X1T8U5-1", "sequence": { "sequence": "MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELMGTPEEEHVGKATSLIESQHHHLLHCLEKTTNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHPGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDGLRPNCKSSQITTAIISIPTPPALTPEGESRPPAASPGPNTNIPSIASNVVKVSAL", "length": 636, "header": "tr|A0A4X1T8U5-1|A0A4X1T8U5_PIG Isoform 1 of Potassium voltage-gated channel subfamily D member 3 OS=Sus scrofa OX=9823 GN=KCND3 PE=4 SV=1 CANONICAL=A0A4X1T8U5-1" }, "locus": { "chromosome": "4", "start_pos": 108616193, "end_pos": 108401895, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103955.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103955.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076041.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076041.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8H8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8H8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100037946", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100037946", "resource": "KEGG Pathway" }, { "id": "R-SSC-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" }, { "id": "R-SSC-5576894", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576894", "resource": "Reactome", "description": "Phase 1 - inactivation of fast Na+ channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "postsynaptic specialization membrane", "id": "GO:0099634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization", "id": "GO:1902282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902282", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "A-type (transient outward) potassium channel activity", "id": "GO:0005250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005250", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "protein tetramerization", "id": "GO:0051262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051262", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "regulation of heart rate by cardiac conduction", "id": "GO:0086091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086091", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" }, { "name": "potassium ion export across plasma membrane", "id": "GO:0097623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097623", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8U5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T8U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8U5" }, { "id": "SM00225", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 139, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T8P8-1", "uniprot_ac": "A0A4X1T8P8", "uniprot_id": "A0A4X1T8P8_PIG", "mass": { "chemical_mass": 46773.0, "monoisotopic_mass": 46773.0 }, "refseq": { "ac": "XP_020928869", "name": "testican-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928869" }, "gene_names": [ { "name": "SPOCK2", "type": "recommended", "evidence": [ { "id": "A0A4X1T8P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8" } ] }, { "name": "SPOCK2", "type": "synonym", "evidence": [ { "id": "XP_020928869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928869" } ] } ], "protein_names": [ { "name": "Testican-2", "type": "recommended", "evidence": [ { "id": "A0A4X1T8P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8/entry#names_and_taxonomy" } ] }, { "name": "SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2", "type": "synonym", "evidence": [ { "id": "A0A4X1T8P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8/entry#names_and_taxonomy" } ] }, { "name": "testican-2", "type": "synonym", "evidence": [ { "id": "XP_020928869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928869" } ] } ], "function": [ { "annotation": "May participate in diverse steps of neurogenesis. Binds calcium.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0IG64", "url": "https://www.uniprot.org/uniprotkb/A0A8D0IG64#function" }, { "database": "UniProtKB", "id": "ARBA00054013", "url": "https://www.uniprot.org/uniprotkb/ARBA00054013#function" }, { "database": "UniProtKB", "id": "A0A8W4FC70", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FC70#function" }, { "database": "UniProtKB", "id": "A0A4X1T8P8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8P8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SPOCK2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8", "locus": { "chromosome": "14", "start_pos": 74938166, "end_pos": 74968018, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010283", "url": "https://www.ensembl.org/id/ENSSSCG00000010283" } ] } } ], "crossref": [ { "id": "A0A4X1T8P8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T8P8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00191", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00191", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100158017", "url": "https://www.ncbi.nlm.nih.gov/gene/100158017", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100158017", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158017", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1T8P8", "url": "https://www.orthodb.org/?gene=A0A4X1T8P8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13866", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13866", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13866:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13866:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00086", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00086", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10591", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10591", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020928869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928869", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T8P8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0IG64", "url": "https://www.uniprot.org/uniprotkb/A0A8D0IG64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0IG64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0IG64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FC70", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FC70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FC70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FC70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAPGCGRLALPLLLLTAAALAEGDTKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQPALKLHGNKDTACKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLTVRCEGPCPCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSVSSGANLASGLDKSLGASCKDSIGWMFSKLDTSADLFLDQMELAAINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERIQIQEAAKKKPGVFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDGGYIW", "length": 424, "header": "tr|A0A4X1T8P8-1|A0A4X1T8P8_PIG Isoform 1 of Testican-2 OS=Sus scrofa OX=9823 GN=SPOCK2 PE=4 SV=1 CANONICAL=A0A4X1T8P8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T8P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8/entry#A0A4X1T8P8-1", "sequence": { "sequence": "MGAPGCGRLALPLLLLTAAALAEGDTKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQPALKLHGNKDTACKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLTVRCEGPCPCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSVSSGANLASGLDKSLGASCKDSIGWMFSKLDTSADLFLDQMELAAINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERIQIQEAAKKKPGVFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDGGYIW", "length": 424, "header": "tr|A0A4X1T8P8-1|A0A4X1T8P8_PIG Isoform 1 of Testican-2 OS=Sus scrofa OX=9823 GN=SPOCK2 PE=4 SV=1 CANONICAL=A0A4X1T8P8-1" }, "locus": { "chromosome": "14", "start_pos": 74967435, "end_pos": 74941908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091923.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091923.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079564.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079564.1" } ] } }, { "isoform_ac": "A0A8D0IG64-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8/entry#A0A8D0IG64-1", "sequence": { "sequence": "MGAPGCGRLALPLLLLTAAALAEGDTKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRDDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQPALKLHGNKDTACKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLTVRCEGPCPCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSVSSGANLASGLDKSLGASCKDSIGWMFSKLDTSADLFLDQMELAAINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERIQIQEAAKKKPGVFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDGGYIW", "length": 421, "header": "tr|A0A8D0IG64-1|A0A4X1T8P8_PIG Computationally mapped isoform of Testican-2 OS=Sus scrofa OX=9823 GN=SPOCK2 PE=4 SV=1 CANONICAL=A0A4X1T8P8-1" }, "locus": { "chromosome": "14", "start_pos": 74967435, "end_pos": 74941908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047219.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047219.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047795.3", "url": "https://www.ensembl.org/id/ENSSSCP00000047795.3" } ] } }, { "isoform_ac": "A0A8W4FC70-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8/entry#A0A8W4FC70-1", "sequence": { "sequence": "MGAPGCGRLALPLLLLTAAALAEGDTKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRDDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQPALKLHGNKDTACKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLTVRCEGPCPCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSVSSGANLASGLDKSLGASCKDSIGWMFSKLDTSADLFLDQMELAAINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERIQIQEAAKKKPGVFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADQRPGQKQAACECIWKIQLARTPWGALP", "length": 442, "header": "tr|A0A8W4FC70-1|A0A4X1T8P8_PIG Computationally mapped isoform of Testican-2 OS=Sus scrofa OX=9823 GN=SPOCK2 PE=4 SV=1 CANONICAL=A0A4X1T8P8-1" }, "locus": { "chromosome": "14", "start_pos": 74967435, "end_pos": 74941460, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101065.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101065.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075892.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075892.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0IG64", "url": "https://www.uniprot.org/uniprotkb/A0A8D0IG64" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100158017", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158017", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8P8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8" } ], "pmid": "" }, { "name": "extracellular matrix binding", "id": "GO:0050840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050840", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8P8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8" } ], "pmid": "" }, { "name": "glycosaminoglycan binding", "id": "GO:0005539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005539", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8P8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8" } ], "pmid": "" }, { "name": "metalloendopeptidase inhibitor activity", "id": "GO:0008191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008191", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8P8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8P8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8P8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of cell-substrate adhesion", "id": "GO:0010810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010810", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8P8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T8P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 181, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1T8P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8P8" }, { "id": "PS51162", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51162" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thyroglobulin type-1", "eco_id": "ECO_0000259", "start_pos": 310, "end_pos": 376, "start_aa": "Lys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T8S2-1", "uniprot_ac": "A0A4X1T8S2", "uniprot_id": "A0A4X1T8S2_PIG", "mass": { "chemical_mass": 34546.0, "monoisotopic_mass": 34546.0 }, "refseq": { "ac": "XP_001926855", "name": "leucine zipper transcription factor-like protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926855" }, "gene_names": [ { "name": "LZTFL1", "type": "recommended", "evidence": [ { "id": "A0A4X1T8S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2" } ] }, { "name": "LZTFL1", "type": "synonym", "evidence": [ { "id": "XP_001926855", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926855" } ] } ], "protein_names": [ { "name": "Leucine zipper transcription factor-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A4X1T8S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2/entry#names_and_taxonomy" } ] }, { "name": "leucine zipper transcription factor-like protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_001926855", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926855" } ] } ], "function": [ { "annotation": "Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8R7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8R7#function" }, { "database": "UniProtKB", "id": "ARBA00024898", "url": "https://www.uniprot.org/uniprotkb/ARBA00024898#function" }, { "database": "UniProtKB", "id": "A0A4X1T8S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2#function" }, { "database": "UniProtKB", "id": "F1SNZ1", "url": "https://www.uniprot.org/uniprotkb/F1SNZ1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LZTFL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2", "locus": { "chromosome": "13", "start_pos": 28977503, "end_pos": 29005445, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011314", "url": "https://www.ensembl.org/id/ENSSSCG00000011314" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011314", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011314", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152547", "url": "https://www.ncbi.nlm.nih.gov/gene/100152547", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152547", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152547", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QMEGTTA", "url": "https://omabrowser.org/oma/group/QMEGTTA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T8S2", "url": "https://www.orthodb.org/?gene=A0A4X1T8S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21635", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21635", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21635:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21635:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5620922", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001926855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926855", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T8R7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T8S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SNZ1", "url": "https://www.uniprot.org/uniprotkb/F1SNZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SNZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1SNZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEETFTIDEVSEVLNGLQAVVHGEVESELINTAYTNVLLLRQLFSQAEKWYLKLQTDISELENRELLEQVAEFEKAEFISSNKKPIIDNIRPKLAPLNEGGAAELLNKEILRLQEENEKLKSRLKATETQATNALDEKSKLEKALQDLQLDQGNQKDFVKAQDLSDLENTVAALKSEFQKTLNDQTENQKSLEENLATAKHDLLRVQEQLSMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAKYEPED", "length": 299, "header": "tr|A0A4X1T8S2-1|A0A4X1T8S2_PIG Isoform 1 of Leucine zipper transcription factor-like protein 1 OS=Sus scrofa OX=9823 GN=LZTFL1 PE=1 SV=1 CANONICAL=A0A4X1T8S2-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T8R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2/entry#A0A4X1T8R7-1", "sequence": { "sequence": "PLAWGAVLGFSRSSRPLNPARLPPWLVEETFTIDEVSEVLNGLQAVVHGEVESELINTAYTNVLLLRQLFSQAEKWYLKLQTDISELENRELLEQVAEFEKAEFISSNKKPIIDNIRPKLAPLNEGGAAELLNKEILRLQEENEKLKSRLKATETQATNALDEKSKLEKALQDLQLDQGNQKDFVKAQDLSDLENTVAALKSEFQKTLNDQTENQKSLEENLATAKHDLLRVQEQLSMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAKYEPED", "length": 281, "header": "tr|A0A4X1T8R7-1|A0A4X1T8S2_PIG Computationally mapped isoform of Leucine zipper transcription factor-like protein 1 OS=Sus scrofa OX=9823 GN=LZTFL1 PE=1 SV=1 CANONICAL=A0A4X1T8S2-1" }, "locus": { "chromosome": "13", "start_pos": 28996519, "end_pos": 28977948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000034720.4", "url": "https://www.ensembl.org/id/ENSSSCT00000034720.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029823.2", "url": "https://www.ensembl.org/id/ENSSSCP00000029823.2" } ] } }, { "isoform_ac": "A0A4X1T8S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2/entry#A0A4X1T8S2-1", "sequence": { "sequence": "MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEETFTIDEVSEVLNGLQAVVHGEVESELINTAYTNVLLLRQLFSQAEKWYLKLQTDISELENRELLEQVAEFEKAEFISSNKKPIIDNIRPKLAPLNEGGAAELLNKEILRLQEENEKLKSRLKATETQATNALDEKSKLEKALQDLQLDQGNQKDFVKAQDLSDLENTVAALKSEFQKTLNDQTENQKSLEENLATAKHDLLRVQEQLSMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAKYEPED", "length": 299, "header": "tr|A0A4X1T8S2-1|A0A4X1T8S2_PIG Isoform 1 of Leucine zipper transcription factor-like protein 1 OS=Sus scrofa OX=9823 GN=LZTFL1 PE=1 SV=1 CANONICAL=A0A4X1T8S2-1" }, "locus": { "chromosome": "13", "start_pos": 28996448, "end_pos": 28977948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073548.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073548.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065283.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065283.2" } ] } }, { "isoform_ac": "F1SNZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2/entry#F1SNZ1-1", "sequence": { "sequence": "MARELGADVTGLEVLECMKDPEAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEETFTIDEVSEVLNGLQAVVHGEVESELINTAYTNVLLLRQLFSQAEKWYLKLQTDISELENRELLEQVAEFEKAEFISSNKKPIIDNIRPKLAPLNEGGAAELLNKEILRLQEENEKLKSRLKATETQATNALDEKSKLEKALQDLQLDQGNQKDFVKAQDLSDLENTVAALKSEFQKTLNDQTENQKSLEENLATAKHDLLRVQEQLSMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAK", "length": 315, "header": "tr|F1SNZ1-1|F1SNZ1_PIG Computationally mapped isoform of Leucine zipper transcription factor-like protein 1 OS=Sus scrofa OX=9823 GN=LZTFL1 PE=1 SV=3 CANONICAL=A0A4X1T8S2-1" }, "locus": { "chromosome": "13", "start_pos": 29005290, "end_pos": 28978987, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012386.6", "url": "https://www.ensembl.org/id/ENSSSCT00000012386.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012062.4", "url": "https://www.ensembl.org/id/ENSSSCP00000012062.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8R7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8R7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152547", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152547", "resource": "KEGG Pathway" }, { "id": "R-SSC-5620922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620922", "resource": "Reactome", "description": "BBSome-mediated cargo-targeting to cilium" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GYY4-1", "protein_name": "Leucine zipper transcription factor-like protein 1", "gene_name": "Lztfl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNYPCLYARLCCLTTVCRQPQAELGLNEHHQNEVINYMRFARSKRGLRLKTVDACFQDLKESRLVEETFTMDEVMEVLNGLQSVVHSEVESELINTAYTNVLLLRQLFSQAEKWYLKLQTDISELENRELLEQIAEFEKAEFTSSSKKPIIDITKPKLVPINEGGTTELLNKEILRLQQENEKLKSRLKTIEIQTTNALDEKSKLERTLQDLQIDQENQQDFIKAHDLDDLENTVAALRDEFQKTLNDQTENQKSLEQNLAAAKHDLLRVQEQLSLAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAKYESED", "length": 319 }, "evidence": [ { "id": "A0A4X1T8S2", "url": "https://omabrowser.org/oma/group/A0A4X1T8S2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3ZBL4-1", "protein_name": "Leucine zipper transcription factor-like protein 1", "gene_name": "LZTFL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEETFTVDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFSQAEKWYLKLQTDISELENRELLEQVAEFEKAEFTSSNKKSIIDSMKPKLAPLHEGGAAELLNKEIIRLQEENEKLKSRLKTIESQATDALDEKSKLERALQDLQLEHGSQKDFIKAQDLSDLENTVAALKSEFQKTLNDQTENQKSLEENLATAKHDLLRVQEQLSMAEKELEKKFQQTAAFRNMKEILTKKNDQIKDLRKRLAKYEPED", "length": 299 }, "evidence": [ { "id": "A0A4X1T8S2", "url": "https://omabrowser.org/oma/group/A0A4X1T8S2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q562C6-1", "protein_name": "Leucine zipper transcription factor-like protein 1", "gene_name": "Lztfl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEETFTIDEVSEVLNGLQAVVHSEVESELINTAHTNVLLLRQLFSQAEKWYLKLQTDVSELENRELLEQVAEFEKAEFASSNKKPIIDITKPKLVPINEGGTTELLNKEILRLQQENEKLKSRLKTIETQAVNALDEKSKLERVLQDLQLDQGNQQDFIKAQDLDDLENTVAALKSEFQKTLNDKTENQKSLEENLAAAKHDLLRVQEQLSMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAKYESED", "length": 299 }, "evidence": [ { "id": "A0A4X1T8S2", "url": "https://omabrowser.org/oma/group/A0A4X1T8S2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JHQ5-1", "protein_name": "Leucine zipper transcription factor-like protein 1", "gene_name": "Lztfl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKDSRLVEETFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFSQAEKWYLKLQTDISELENRELLEQVAEFEKAEFVSSSKKPIIDITKPKLVPINEGGTTELLNKEILRLQQENEKLKSRLKTIEIQAVNALDEKSKLERVLQDLQLDQENQQDLLKAQDLDDLENTVATLRSEFQKTLNDKTENQKSLEENLAAAKHDLLRVQEQLSMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAKYESED", "length": 299 }, "evidence": [ { "id": "A0A4X1T8S2", "url": "https://omabrowser.org/oma/group/A0A4X1T8S2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQ48-1", "protein_name": "Leucine zipper transcription factor-like protein 1", "gene_name": "LZTFL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED", "length": 299 }, "evidence": [ { "id": "A0A4X1T8S2", "url": "https://omabrowser.org/oma/group/A0A4X1T8S2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2" } ], "pmid": "" }, { "name": "manchette", "id": "GO:0002177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002177", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2" } ], "pmid": "" }, { "name": "negative regulation of protein localization to cilium", "id": "GO:1903565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903565", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2" } ], "pmid": "" }, { "name": "negative regulation of protein localization to ciliary membrane", "id": "GO:1903568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903568", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T8S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T8S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T964-1", "uniprot_ac": "A0A4X1T964", "uniprot_id": "A0A4X1T964_PIG", "mass": { "chemical_mass": 35633.0, "monoisotopic_mass": 35633.0 }, "refseq": { "ac": "XP_001929262", "name": "olfactory receptor 11A1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929262" }, "gene_names": [ { "name": "LOC100155213", "type": "recommended", "evidence": [ { "id": "A0A4X1T964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964" } ] }, { "name": "LOC100155213", "type": "synonym", "evidence": [ { "id": "XP_001929262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929262" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1T964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 11A1-like", "type": "synonym", "evidence": [ { "id": "XP_001929262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929262" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T964", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T964", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100155213", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964", "locus": {} } ], "crossref": [ { "id": "A0A4X1T964", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T964", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15911", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15911", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155213", "url": "https://www.ncbi.nlm.nih.gov/gene/100155213", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155213", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155213", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MCLSKKP", "url": "https://omabrowser.org/oma/group/MCLSKKP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T964", "url": "https://www.orthodb.org/?gene=A0A4X1T964", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242:SF365", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242:SF365", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001929262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929262", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T964", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T964-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVILPWENQTVESFVLRGFSSIQELNIFLFMMFLVFYILIVSGNILIVLLVLFSHRLHTPMYFFLVNLSFLEIWYTSNIVPKMLIIILAKQKTISVSGCLAQFYFFGSLAATECLLLAVMSYDRYLAICQPLHYPILMTGPFCVRLAASSWLCCFLLTAVTMVLLSRLTFCGPNEIDHFFCDFTPLVHLSCMDTSLTEMVAYSTSSAVTLFPFLLITASYSCILAVILRIPSGTGRQKAFSTCSSHLTVVIVFYGTLIATYLVPSANSSQLLRKGFSLLYTILTPMFNPLIYSLRNRDILEALKKCWSKKPDFLV", "length": 315, "header": "tr|A0A4X1T964-1|A0A4X1T964_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100155213 PE=3 SV=1 CANONICAL=A0A4X1T964-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T964-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964/entry#A0A4X1T964-1", "sequence": { "sequence": "MVILPWENQTVESFVLRGFSSIQELNIFLFMMFLVFYILIVSGNILIVLLVLFSHRLHTPMYFFLVNLSFLEIWYTSNIVPKMLIIILAKQKTISVSGCLAQFYFFGSLAATECLLLAVMSYDRYLAICQPLHYPILMTGPFCVRLAASSWLCCFLLTAVTMVLLSRLTFCGPNEIDHFFCDFTPLVHLSCMDTSLTEMVAYSTSSAVTLFPFLLITASYSCILAVILRIPSGTGRQKAFSTCSSHLTVVIVFYGTLIATYLVPSANSSQLLRKGFSLLYTILTPMFNPLIYSLRNRDILEALKKCWSKKPDFLV", "length": 315, "header": "tr|A0A4X1T964-1|A0A4X1T964_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100155213 PE=3 SV=1 CANONICAL=A0A4X1T964-1" }, "locus": { "chromosome": "4", "start_pos": 109348033, "end_pos": 109347089, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007449.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007449.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007254.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007254.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T964", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155213", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155213", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8VFC3-1", "protein_name": "Olfactory receptor", "gene_name": "Or11i1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMTLSWENQTVIVEFVLRGFSSILQLNISLFIMFCIFYILTISGNILIVFLVLCNHALHTPMYFFLVNLSFLEVCYTSNIVPKMLLIIIADQKTISVVGCLAQFYFFGSLAATECLLLAVMSYDRYLAICQPLRYPILMTGSLCFRLAIGSWFCCFFLTAITMVLLCRQNFCGPNEIDHFFCDFAPLIHLSCMDTSLIETVAFATSSAVTLVPFFLITISYSCILIAILRIPSGTGRKKAFSTCSSHLTVVTVFYGTLIATYLVPSANSSQYLRKGFSLLYTILTPMFNPIIYSLRNRDIHEALKKCLSKKSDFLI", "length": 316 }, "evidence": [ { "id": "A0A4X1T964", "url": "https://omabrowser.org/oma/group/A0A4X1T964/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T964", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T964", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T964", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T964" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 292, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 267, "end_pos": 269 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1T9C9-1", "uniprot_ac": "A0A4X1T9C9", "uniprot_id": "A0A4X1T9C9_PIG", "mass": { "chemical_mass": 35423.0, "monoisotopic_mass": 35423.0 }, "refseq": { "ac": "XP_020937555", "name": "olfactory receptor 6B1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937555" }, "gene_names": [ { "name": "LOC110258605", "type": "recommended", "evidence": [ { "id": "A0A4X1T9C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9" } ] }, { "name": "LOC110258605", "type": "synonym", "evidence": [ { "id": "XP_020937555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937555" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1T9C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6B1", "type": "synonym", "evidence": [ { "id": "XP_020937555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937555" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9C9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9C9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110258605", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9", "locus": {} } ], "crossref": [ { "id": "A0A4X1T9C9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1T9C9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110258605", "url": "https://www.ncbi.nlm.nih.gov/gene/110258605", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110258605", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258605", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISLMCTE", "url": "https://omabrowser.org/oma/group/ISLMCTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1T9C9", "url": "https://www.orthodb.org/?gene=A0A4X1T9C9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242:SF253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242:SF253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020937555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937555", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1T9C9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1T9C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVENQTRVTMFILVGFPGPWGMRVAVFLLFFGAYILTVAENMIIILSVQWSRPLHKPMYFFLANLSFLETWYISVTVPKLLFSFWSMRNSISFTHCMIQLYFFIALMCTECVLLAAMAYDRYVAICLPLHYTTSMSHGICFRLVLGSWIIGFGISLAKIYFISQLSFCGPNVINHFFCDISPVLNLSCKDMSIAELVDFVLALIIFLFPLSITVLSYGCILATILRMPTGKKKAFSTCASHLVVVTIFYSATIFMYARPRAIHTFNMNKVISIFYAIVTPALNPFIYCLRNREVKEALKKLACCQSIHSD", "length": 311, "header": "tr|A0A4X1T9C9-1|A0A4X1T9C9_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258605 PE=3 SV=1 CANONICAL=A0A4X1T9C9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T9C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9/entry#A0A4X1T9C9-1", "sequence": { "sequence": "MEVENQTRVTMFILVGFPGPWGMRVAVFLLFFGAYILTVAENMIIILSVQWSRPLHKPMYFFLANLSFLETWYISVTVPKLLFSFWSMRNSISFTHCMIQLYFFIALMCTECVLLAAMAYDRYVAICLPLHYTTSMSHGICFRLVLGSWIIGFGISLAKIYFISQLSFCGPNVINHFFCDISPVLNLSCKDMSIAELVDFVLALIIFLFPLSITVLSYGCILATILRMPTGKKKAFSTCASHLVVVTIFYSATIFMYARPRAIHTFNMNKVISIFYAIVTPALNPFIYCLRNREVKEALKKLACCQSIHSD", "length": 311, "header": "tr|A0A4X1T9C9-1|A0A4X1T9C9_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258605 PE=3 SV=1 CANONICAL=A0A4X1T9C9-1" }, "locus": { "chromosome": "AEMK02000390.1", "start_pos": 284042, "end_pos": 283110, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044414.2", "url": "https://www.ensembl.org/id/ENSSSCT00000044414.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057793.1", "url": "https://www.ensembl.org/id/ENSSSCP00000057793.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 280, "start_aa": "Thr", "end_pos": 280, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr280", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9C9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110258605", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258605", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O95007-1", "protein_name": "Olfactory receptor 6B1", "gene_name": "OR6B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELENQTRVTKFILVGFPGSLSMRAAMFLIFLVAYILTVAENVIIILLVLQNRPLHKPMYFFLANLSFLETWYISVTVPKLLFSFWSVNNSISFTLCMIQLYFFIALMCTECVLLAAMAYDRYVAICRPLHYPTIMSHGLCFRLALGSWAIGFGISLAKIYFISCLSFCGPNVINHFFCDISPVLNLSCTDMSITELVDFILALVIFLFPLFITVLSYGCILATILCMPTGKQKAFSTCASHLVVVTIFYSAIIFMYARPRVIHAFNMNKIISIFYAIVTPSLNPFIYCLRNREVKEALKKLAYCQASRSD", "length": 311 }, "evidence": [ { "id": "A0A4X1T9C9", "url": "https://omabrowser.org/oma/group/A0A4X1T9C9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VGW8-1", "protein_name": "Olfactory receptor", "gene_name": "Or6b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDVDNQTRVTKFILVGFPGSLSMRAAVFLMFLVAYILTVAENVIIILLVQQNRPLHKPMYFFLANLSFLETWYISVTVPKLLFSFWSMSNSISFTHCMIQLYFFIALMCTECVLLAAMAYDRYVAICRPLHYPTIMSHGLCFRLALGSWVIGFGISLAKIYFISRLSFCGPNVINHFFCDISPVLNLSCTDMSIAELVDFVLALVIFLFPLSITVLSYGCILATVLRMPTGKQKAFSTCASHLVVVTIFYSATIFMYARPRAIHAFNMNKVISIFYAIVTPALNPFIYCLRNREVKEALKKLIYCQVIRSD", "length": 311 }, "evidence": [ { "id": "A0A4X1T9C9", "url": "https://omabrowser.org/oma/group/A0A4X1T9C9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9C9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9C9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9C9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1T9C9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1T9C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T9C9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 288, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 280 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TA74-1", "uniprot_ac": "A0A4X1TA74", "uniprot_id": "A0A4X1TA74_PIG", "mass": { "chemical_mass": 81858.0, "monoisotopic_mass": 81858.0 }, "refseq": { "ac": "XP_001926597", "name": "disintegrin and metalloproteinase domain-containing protein 30", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926597" }, "gene_names": [ { "name": "ADAM30", "type": "recommended", "evidence": [ { "id": "A0A4X1TA74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" } ] }, { "name": "ADAM30", "type": "synonym", "evidence": [ { "id": "XP_001926597", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926597" } ] } ], "protein_names": [ { "name": "ADAM metallopeptidase domain 30", "type": "synonym", "evidence": [ { "id": "A0A4X1TA74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74/entry#names_and_taxonomy" } ] }, { "name": "disintegrin and metalloproteinase domain-containing protein 30", "type": "synonym", "evidence": [ { "id": "XP_001926597", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926597" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ADAM30", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74", "locus": { "chromosome": "4", "start_pos": 101316893, "end_pos": 101314710, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006713", "url": "https://www.ensembl.org/id/ENSSSCG00000006713" } ] } } ], "crossref": [ { "id": "A0A4X1TA74", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TA74", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156604", "url": "https://www.ncbi.nlm.nih.gov/gene/100156604", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156604", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156604", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICGRLQC", "url": "https://omabrowser.org/oma/group/ICGRLQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TA74", "url": "https://www.orthodb.org/?gene=A0A4X1TA74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF148", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF148", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2534343", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2534343", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001926597", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926597", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TA74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TA74-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSVRTFLSQGPLLPTLVLVVLLVDSLGKDLNLPPGWDFDSYEITIPKKLSFRGGVQGVAKHVSYLLQVKGKSHVLHLWPKRFLLPRNLQVFSFTELGRLWEDHPYIPSNCNYMGLVEGNQDSEATLSTCMGVLRGILKIDASHYQIEPLKASSSFEHVIYLLKKEEEFPHQICGLTDDETLKQMAQHKNVARISDFSQSYMHQKYLELALVFDHSRYIFLNSNLSRVINDAILLSSIMDTYFQDVRMRIHLTGVEVWTDEDKIRLTYPKLEQVLGQFMVYRTSVLNARFPVDWIHLYLKRNYSDSLALYLGNVCTKFHAGSTSVFPDVNVLGPATWSTHALGHGVGMRHDEEYCQCKGRHSCIMGSGQYGFSNCSYAHFFAHVYSGAKCLTNIPELSYVVKRCGNKIVEEDEECDCGSIEDCKNDHCCQPDCKFKHGAKCSIGLCCHKCQFRPSGYKCRLEENECDLAEYCNGTSALCPSDTYKQDGTPCKDEAHCFNKACQSRFMQCQKIFGPDATEAPLQCYVAINVIGDQYGNCGISGVREYRKCNRRNALCGRIQCINVNTIPDMPDHTILISTHLHDENLKCWGIGYHPAMVPMGLPDLGVVSDGTSCGRNNVCFNRNCVNSSVLKFDCFPEKCNHRGVCNNNKNCHCMYGWSPPLCEELGYGGSIDSGPPGPLKEGVPTSVQVVSLMFVRLIFLIISVIVVFFKKIIGNFKTQRESNPTT", "length": 727, "header": "tr|A0A4X1TA74-1|A0A4X1TA74_PIG Isoform 1 of ADAM metallopeptidase domain 30 OS=Sus scrofa OX=9823 GN=ADAM30 PE=4 SV=1 CANONICAL=A0A4X1TA74-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TA74-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74/entry#A0A4X1TA74-1", "sequence": { "sequence": "MRSVRTFLSQGPLLPTLVLVVLLVDSLGKDLNLPPGWDFDSYEITIPKKLSFRGGVQGVAKHVSYLLQVKGKSHVLHLWPKRFLLPRNLQVFSFTELGRLWEDHPYIPSNCNYMGLVEGNQDSEATLSTCMGVLRGILKIDASHYQIEPLKASSSFEHVIYLLKKEEEFPHQICGLTDDETLKQMAQHKNVARISDFSQSYMHQKYLELALVFDHSRYIFLNSNLSRVINDAILLSSIMDTYFQDVRMRIHLTGVEVWTDEDKIRLTYPKLEQVLGQFMVYRTSVLNARFPVDWIHLYLKRNYSDSLALYLGNVCTKFHAGSTSVFPDVNVLGPATWSTHALGHGVGMRHDEEYCQCKGRHSCIMGSGQYGFSNCSYAHFFAHVYSGAKCLTNIPELSYVVKRCGNKIVEEDEECDCGSIEDCKNDHCCQPDCKFKHGAKCSIGLCCHKCQFRPSGYKCRLEENECDLAEYCNGTSALCPSDTYKQDGTPCKDEAHCFNKACQSRFMQCQKIFGPDATEAPLQCYVAINVIGDQYGNCGISGVREYRKCNRRNALCGRIQCINVNTIPDMPDHTILISTHLHDENLKCWGIGYHPAMVPMGLPDLGVVSDGTSCGRNNVCFNRNCVNSSVLKFDCFPEKCNHRGVCNNNKNCHCMYGWSPPLCEELGYGGSIDSGPPGPLKEGVPTSVQVVSLMFVRLIFLIISVIVVFFKKIIGNFKTQRESNPTT", "length": 727, "header": "tr|A0A4X1TA74-1|A0A4X1TA74_PIG Isoform 1 of ADAM metallopeptidase domain 30 OS=Sus scrofa OX=9823 GN=ADAM30 PE=4 SV=1 CANONICAL=A0A4X1TA74-1" }, "locus": { "chromosome": "4", "start_pos": 101316890, "end_pos": 101314710, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007354.2", "url": "https://www.ensembl.org/id/ENSSSCT00000007354.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007159.2", "url": "https://www.ensembl.org/id/ENSSSCP00000007159.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156604", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156604", "resource": "KEGG Pathway" }, { "id": "R-SSC-2534343", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2534343", "resource": "Reactome", "description": "Interaction With Cumulus Cells And The Zona Pellucida" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZIP6-1", "protein_name": "ADAM metallopeptidase domain 30", "gene_name": "Adam30", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSVWASLPQHRWLLLAMLFLEAMAEDLLFDPDWGFDSYEITIPKVLSLRKEAQGVDSSLSYLLQIEGKERVVHLRPKKLLLPRHLPVFSFTQEDSLIEDYPHIPDQCNYVGFVEGSQEAESTLSTCMGGLRGVLNIDSRYYQIEPLRASSRFEHVVYLLTEDNFGNETCGVVDEETDGQTAEEEEVARIKNFHQSYKHQRYLELVMVFDLSRYVFTRGNMTRMVEDAILLASIADTYFQDVSLKIQLKALEVWTQFDKIHLYYSSLSQVLGQFVLYKRASLHHRLPADWAHLYIARRYSDATAWSWGRACEEFHAGSASSFLNVNLLGPATWTAHEMGHCVGMYHDEEFCQCRGRKSCVMGTGRTGFSNCSYHQYFLHASYKMSYCLSDFPKLHIVERCGNKIVENKEECDCGSEEECKSDLCCGPDCKWKEGVNCSSGLCCHKCNFLPSGYVCREEENECDLAEYCDGLSGFCPKDYYKQDGTPCRYGGFCFHKGCRSRYLQCQAIFGRRAKEAPRQCYDAVNMIGDQSGNCGIVNATRYTKCHRDNTICGRLQCVNIKALSRFPDHTLLLSTHLKKDNLKCWGTSYHGTMIPHGVPDIGDVNDGTSCGPNRVCLNRTCVDYATLKFDCLPKKCNSRGVCNNKKNCHCTYGWEPPFCVEVGYGGSIDSGPPGPRARLAKVHVLYMLRTILFIFSVIVVCFTQRMKNLFRKRQQKNPAETQGKKR", "length": 726 }, "evidence": [ { "id": "A0A4X1TA74", "url": "https://omabrowser.org/oma/group/A0A4X1TA74/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UKF2-1", "protein_name": "Disintegrin and metalloproteinase domain-containing protein 30", "gene_name": "ADAM30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSVQIFLSQCRLLLLLVPTMLLKSLGEDVIFHPEGEFDSYEVTIPEKLSFRGEVQGVVSPVSYLLQLKGKKHVLHLWPKRLLLPRHLRVFSFTEHGELLEDHPYIPKDCNYMGSVKESLDSKATISTCMGGLRGVFNIDAKHYQIEPLKASPSFEHVVYLLKKEQFGNQVCGLSDDEIEWQMAPYENKARLRDFPGSYKHPKYLELILLFDQSRYRFVNNNLSQVIHDAILLTGIMDTYFQDVRMRIHLKALEVWTDFNKIRVGYPELAEVLGRFVIYKKSVLNARLSSDWAHLYLQRKYNDALAWSFGKVCSLEYAGSVSTLLDTNILAPATWSAHELGHAVGMSHDEQYCQCRGRLNCIMGSGRTGFSNCSYISFFKHISSGATCLNNIPGLGYVLKRCGNKIVEDNEECDCGSTEECQKDRCCQSNCKLQPGANCSIGLCCHDCRFRPSGYVCRQEGNECDLAEYCDGNSSSCPNDVYKQDGTPCKYEGRCFRKGCRSRYMQCQSIFGPDAMEAPSECYDAVNLIGDQFGNCEITGIRNFKKCESANSICGRLQCINVETIPDLPEHTTIISTHLQAENLMCWGTGYHLSMKPMGIPDLGMINDGTSCGEGRVCFKKNCVNSSVLQFDCLPEKCNTRGVCNNRKNCHCMYGWAPPFCEEVGYGGSIDSGPPGLLRGAIPSSIWVVSIIMFRLILLILSVVFVFFRQVIGNHLKPKQEKMPLSKAKTEQEESKTKTVQEESKTKTGQEESEAKTGQEESKAKTGQEESKANIESKRPKAKSVKKQKK", "length": 790 }, "evidence": [ { "id": "A0A4X1TA74", "url": "https://omabrowser.org/oma/group/A0A4X1TA74/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" } ], "pmid": "" }, { "name": "sperm head plasma membrane", "id": "GO:1990913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990913", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TA74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" }, { "id": "PS50214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Disintegrin", "eco_id": "ECO_0000259", "start_pos": 401, "end_pos": 487, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TA74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 631, "end_pos": 664, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TA74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" }, { "id": "PS50215", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50215" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M12B", "eco_id": "ECO_0000259", "start_pos": 205, "end_pos": 395, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A4X1TA74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74#function" }, { "id": "A0A4X1TA74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" }, { "id": "PRU00276", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00276" } ], "binding_site_uniprot": 340, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 340, "end_pos": 340, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TA74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74#function" }, { "id": "A0A4X1TA74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" }, { "id": "PRU00276", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00276" } ], "binding_site_uniprot": 344, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 344, "end_pos": 344, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TA74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74#function" }, { "id": "A0A4X1TA74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA74" }, { "id": "PRU00276", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00276" } ], "binding_site_uniprot": 350, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 350, "end_pos": 350, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 627, "end_pos": 629 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TA98-1", "uniprot_ac": "A0A4X1TA98", "uniprot_id": "A0A4X1TA98_PIG", "mass": { "chemical_mass": 35233.0, "monoisotopic_mass": 35233.0 }, "refseq": { "ac": "XP_020937349", "name": "olfactory receptor 4A47-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937349" }, "gene_names": [ { "name": "LOC102164683", "type": "recommended", "evidence": [ { "id": "A0A4X1TA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98" } ] }, { "name": "LOC102164683", "type": "synonym", "evidence": [ { "id": "XP_020937349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937349" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4A47-like", "type": "synonym", "evidence": [ { "id": "XP_020937349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937349" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA98", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA98", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC102164683", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98", "locus": {} } ], "crossref": [ { "id": "A0A4X1TA98", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TA98", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "102164683", "url": "https://www.ncbi.nlm.nih.gov/gene/102164683", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:102164683", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102164683", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TA98", "url": "https://www.orthodb.org/?gene=A0A4X1TA98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020937349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937349", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TA98", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TA98-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRNNVTYFVLLGLTQNPKEQKVFFIMFLLFYIFTVVGNLLIVVTIAVSKTLNSPMYFFLASLSFMDLTFSSSITPRLISDLFFGENTISFQSCMIQLFTEHFFGGSEIVLLLVMAYDRYVAICKPLHYLVIMRQRVCVVLLVVSWVGGFLHSVIQLSTIYGLPFCGPNVIDHFICDMYPLLKLVCTDTYVTGFLVASNGGLICSITFLLLLISYAVILQSLQNLNQDGRRKALQTCGSHITVVVCFFVPCIFMYVRPTMTFPIDKSLSVFYTIVTPMLNPLIYSLRNSELTNAMKKIWRKSFIYYSK", "length": 309, "header": "tr|A0A4X1TA98-1|A0A4X1TA98_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC102164683 PE=3 SV=1 CANONICAL=A0A4X1TA98-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TA98-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98/entry#A0A4X1TA98-1", "sequence": { "sequence": "MEPRNNVTYFVLLGLTQNPKEQKVFFIMFLLFYIFTVVGNLLIVVTIAVSKTLNSPMYFFLASLSFMDLTFSSSITPRLISDLFFGENTISFQSCMIQLFTEHFFGGSEIVLLLVMAYDRYVAICKPLHYLVIMRQRVCVVLLVVSWVGGFLHSVIQLSTIYGLPFCGPNVIDHFICDMYPLLKLVCTDTYVTGFLVASNGGLICSITFLLLLISYAVILQSLQNLNQDGRRKALQTCGSHITVVVCFFVPCIFMYVRPTMTFPIDKSLSVFYTIVTPMLNPLIYSLRNSELTNAMKKIWRKSFIYYSK", "length": 309, "header": "tr|A0A4X1TA98-1|A0A4X1TA98_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC102164683 PE=3 SV=1 CANONICAL=A0A4X1TA98-1" }, "locus": { "chromosome": "AEMK02000677.1", "start_pos": 311217, "end_pos": 310291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042445.2", "url": "https://www.ensembl.org/id/ENSSSCT00000042445.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048584.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048584.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA98", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102164683", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102164683", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA98", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA98", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TA98", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TA98" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TB16-1", "uniprot_ac": "A0A4X1TB16", "uniprot_id": "A0A4X1TB16_PIG", "mass": { "chemical_mass": 54897.0, "monoisotopic_mass": 54897.0 }, "refseq": { "ac": "NP_001231809", "name": "KAT8 regulatory NSL complex subunit 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231809" }, "gene_names": [ { "name": "KANSL2", "type": "recommended", "evidence": [ { "id": "A0A4X1TB16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16" } ] }, { "name": "C12orf41", "type": "synonym", "evidence": [ { "id": "NP_001231809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231809" } ] }, { "name": "C5H12orf41", "type": "synonym", "evidence": [ { "id": "NP_001231809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231809" } ] }, { "name": "KANSL2", "type": "synonym", "evidence": [ { "id": "NP_001231809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231809" } ] } ], "protein_names": [ { "name": "KAT8 regulatory NSL complex subunit 2", "type": "recommended", "evidence": [ { "id": "A0A4X1TB16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16/entry#names_and_taxonomy" } ] }, { "name": "KAT8 regulatory NSL complex subunit 2", "type": "synonym", "evidence": [ { "id": "NP_001231809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231809" } ] }, { "name": "NSL complex protein NSL2", "type": "synonym", "evidence": [ { "id": "A0A4X1TB16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16/entry#names_and_taxonomy" } ] }, { "name": "Non-specific lethal 2 homolog", "type": "synonym", "evidence": [ { "id": "A0A4X1TB16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites and promotes transcription initiation. Required for NSL complex stability and for transcription of intraciliary transport genes in both ciliated and non-ciliated cells by regulating histone H4 acetylation at 'Lys-5'- and 'Lys-12' (H4K5ac and H4K12ac). This is necessary for cilium assembly in ciliated cells and for organization of the microtubule cytoskeleton in non-ciliated cells. Required within the NSL complex to maintain nuclear architecture stability by promoting KAT8-mediated acetylation of lamin LMNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16#function" }, { "database": "UniProtKB", "id": "ARBA00093359", "url": "https://www.uniprot.org/uniprotkb/ARBA00093359#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KANSL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16", "locus": { "chromosome": "5", "start_pos": 79281588, "end_pos": 79314995, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000842", "url": "https://www.ensembl.org/id/ENSSSCG00000000842" } ] } } ], "crossref": [ { "id": "100513860", "url": "https://www.ncbi.nlm.nih.gov/gene/100513860", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513860", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513860", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EGHEFCI", "url": "https://omabrowser.org/oma/group/EGHEFCI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TB16", "url": "https://www.orthodb.org/?gene=A0A4X1TB16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13453:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13453:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13891", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13891", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3214847", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214847", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001231809", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231809", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TB16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TB16-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRIRIHVLPTNRGRITPVPRSQEPLSCSFTHRPCSQPRLEGQEFCIKHILEDKNAPFKQCSYISTKNGKRCPCAAPKPEKKDGVSFCAEHARRNALALHAQMKKTNPGPVGETLLCQLSSYAKTELGSQTPESSRSEASRILDEDSWSDGEQEPITVDQTWRGDPDSEADSIDSDQEDPLKHAGVYTAEEVALIMREKLIRLQSLYIDQFKRLQHLLKEKKRRYLHNRKVEHEALGSSLLTGPEGLLAKERENLKRLKCLRRYRQRYGVEALLHRQLKERRMLATDGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEVPCNKPVPISLSEDPCCPLHFQLPPQMYKPEQVLSVPDDLEAGPMDLYLSAAELQPTESLPLEFSDDLDVVGDSMQCPPSPLLFDPSLTLEDHSVKEIAEGSVDVLGQMQMAGDGCRSQGFRNSEKAASLPQSGVATANGKLESTSVS", "length": 491, "header": "tr|A0A4X1TB16-1|A0A4X1TB16_PIG Isoform 1 of KAT8 regulatory NSL complex subunit 2 OS=Sus scrofa OX=9823 GN=KANSL2 PE=4 SV=1 CANONICAL=A0A4X1TB16-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TB16-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16/entry#A0A4X1TB16-1", "sequence": { "sequence": "MNRIRIHVLPTNRGRITPVPRSQEPLSCSFTHRPCSQPRLEGQEFCIKHILEDKNAPFKQCSYISTKNGKRCPCAAPKPEKKDGVSFCAEHARRNALALHAQMKKTNPGPVGETLLCQLSSYAKTELGSQTPESSRSEASRILDEDSWSDGEQEPITVDQTWRGDPDSEADSIDSDQEDPLKHAGVYTAEEVALIMREKLIRLQSLYIDQFKRLQHLLKEKKRRYLHNRKVEHEALGSSLLTGPEGLLAKERENLKRLKCLRRYRQRYGVEALLHRQLKERRMLATDGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEVPCNKPVPISLSEDPCCPLHFQLPPQMYKPEQVLSVPDDLEAGPMDLYLSAAELQPTESLPLEFSDDLDVVGDSMQCPPSPLLFDPSLTLEDHSVKEIAEGSVDVLGQMQMAGDGCRSQGFRNSEKAASLPQSGVATANGKLESTSVS", "length": 491, "header": "tr|A0A4X1TB16-1|A0A4X1TB16_PIG Isoform 1 of KAT8 regulatory NSL complex subunit 2 OS=Sus scrofa OX=9823 GN=KANSL2 PE=4 SV=1 CANONICAL=A0A4X1TB16-1" }, "locus": { "chromosome": "5", "start_pos": 79304942, "end_pos": 79282163, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061249.2", "url": "https://www.ensembl.org/id/ENSSSCT00000061249.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057195.1", "url": "https://www.ensembl.org/id/ENSSSCP00000057195.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513860", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513860", "resource": "KEGG Pathway" }, { "id": "R-SSC-3214847", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214847", "resource": "Reactome", "description": "HATs acetylate histones" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4LHU7-1", "protein_name": "KAT8 regulatory NSL complex subunit 2", "gene_name": "dgt1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSFSPNQLRQCARFTGTPCTPDKEHQLREQIHSELVKIKYCANPTYECSLMRIEGYEYCIRHILRDPRSNFRQCSHVYSNGRKCINAVAKYDNKKELILTTLCFEHNRQTQLQKTHMNVGRIRSRVETNETLLHSLSSHINVEDIKPEVKKIERDDDEIDVVSPHVTPFVTQDHRNSIGHVVESSRKRRRILDYASDSSSNDADPPCLRNTAQDIEFYESDHESIDSEDDDPLKHAGVFTRAEAVKIAETKLIKLQGLYREQISYLQNVLRQRRRKYLHDIRRERELYCSIHDQLKDTPHERKLYEQLKALNSYHRRQGVEAVLYKKLKEKRARDALYAAKSSSNPKCVFTEGGVKCGERTLPCCKHCRKHILEDKRQVLFRACGVERSGVVCQEPVASILEDSSCVLHLTVAPAKRQYIQKFYEVPSTPPVESIFAAGRGLDNFVGEDPRNEPQPEGDDLLDFANGIFDFDLDGVDDLANSLDDDYSMFLDMDSDLGLAIEDDGVESDPVDLGLEEEGDGGSNDSVGPAESQAQDNLIADNFELEEPSVQDNNELNFDIDESESNVNEVLRLLEGIEHMPWFDALMN", "length": 589 }, "evidence": [ { "id": "A0A4X1TB16", "url": "https://omabrowser.org/oma/group/A0A4X1TB16/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "G3ILA7-1", "protein_name": "KAT8 regulatory NSL complex subunit 2", "gene_name": "Kansl2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNRIRIHVLPTNRGRITPVPRSQEPLSCSFTHRPCSQPRLEGQEFCIKHILEDKNAPFKQCSYISTKNGKRCPSAAPKPEKKDGVSFCAEHARRNALALHAQMKKNNPGPMGETLLCQLSSYAKTELGSQTPESSRSEASRILDEDSWSDGDQEPITVDQTWRGDPDSEADSIDSDQEDPLKHAGVYTAEEVALIMREKLIRLQSLYIDQFKRLQHLLKEKKRRYLHNRKVEHEALGSSLLTGPEGLLAKERENLKRLKCLRRYRQRYGVEALLHRQLKERRMLATDGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEVPCNKPVPVSLSEDPCCPLHFQLPPQMYKPEQVLSVPDDLEAGPMDLYLSAAELQPTESLPLEFSDDLDVVGDGMPCPPSPLLFDPSLTLEDHSDKEIAGGLGQMQVTGDGCRSQVPRNLEKACASFPQRGLTTANGKPEPTSIS", "length": 488 }, "evidence": [ { "id": "A0A4X1TB16", "url": "https://omabrowser.org/oma/group/A0A4X1TB16/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2NL14-1", "protein_name": "KAT8 regulatory NSL complex subunit 2", "gene_name": "KANSL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNRIRIHVLPTNRGRITPVPRSQEPLSCSFTHRPCSQPRLEGQEFCIKHILEDKNAPFKQCSYVSTKNGKRCPSAAPKPEKKDGASFCAEHARRNALALHAQMKKTSPGPVGETLLCQLSSYAKTELGSQTPESSRSEASRILDEDSWSDGDQEPITVDQTWRGDPDSEADSIDSDQEDPLKHAGVYTAEEVALIMREKLIRLQSLYIDQFKRLQHLLKEKKRRYLHNRKVEHEALGSSLLTGPEGLLAKERENLKRLKCLRRYRQRYGVEALLHRQLKERRMLATDGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEVPCNKPVPVSLSEDPCCPLHFQLPPQMYKPEQDLDVVGDGMQCPPSPLLFDPSLTLEDHPVKEIAEGPVDILGQMQMAGDGCRSQGPRNSEKAPAPLPQSGIATANGKPEPTSVS", "length": 458 }, "evidence": [ { "id": "A0A4X1TB16", "url": "https://omabrowser.org/oma/group/A0A4X1TB16/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AY70-1", "protein_name": "KAT8 regulatory NSL complex subunit 2", "gene_name": "Kansl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNRIRIHVLPTNRGRITPVPRSQEPLSCSFTHRPCSQPRLEGQEFCLKHILEDKNAPFKQCSYISTKNGKRCPSAAPKPEKKDGVSFCAEHARRNALALHAQMKKSNPGPMGETLLCQLSSYAKTELGSQTPESSRSEASRILDEDSWSDGDQEPITVDQTWRGDPDSEADSIDSDQEDPLKHAGVYTAEEVALIMREKLIRLQSLYIDQFKRLQHLLKEKKRRYLHNRKVEHEALGSSLLTGPEGLLAKERENLKRLKCLRRYRQRYGVEALLHRQLKERRMLATEGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEVPCNKPVPVSLSEDPCCPLHFQLPPQMYKPEQVLSVPDGLEAGPMDLYLSAAELQPTESLPLELSDDLDVVGDGMPCPPSPLLFDPSLTLEDHSVTEIAGGPGQIQVAGDGCRSQGPHNVEKTCAPFPQRGLATANGKPEPTSIS", "length": 488 }, "evidence": [ { "id": "A0A4X1TB16", "url": "https://omabrowser.org/oma/group/A0A4X1TB16/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BQR4-1", "protein_name": "KAT8 regulatory NSL complex subunit 2", "gene_name": "Kansl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNRIRIHVLPTNRGRITPVPRSQEPLSCSFTHRPCSQPRLEGQEFCIKHILEDKNAPFKQCSYVSTKNGKRCPSAAPKPEKKDGVSFCAEHARRNALALHAQMKKSNPGPMGETLLCQLSSYAKTELGSQTPESSRSEASRILDEDSWSDGDQEPITVDQTWRGDPDSEADSIDSDQEDPLKHAGVYTAEEVALIMREKLIRLQSLYIDQFKRLQHLLKEKKRRYLHNRKVEHEALGSSLLTGPEGLLAKERENLKRLKCLRRYRQRYGVEALLHRQLKERRMLATDGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEVPCNKPVPVSLSEDPCCPLHFQLPPQMYKPEQVLSVPDDLEAGPMDLYLSAAELQPTESLPLEFSDDLDVVGDGMPCPPSPLLFDPSLTLEDHSVTESAGDAGQMQAAGDGCRSQGARSVEKAAFPQRGLATANGKPEPTSIS", "length": 486 }, "evidence": [ { "id": "A0A4X1TB16", "url": "https://omabrowser.org/oma/group/A0A4X1TB16/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H9L4-1", "protein_name": "KAT8 regulatory NSL complex subunit 2", "gene_name": "KANSL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRIRIHVLPTNRGRITPVPRSQEPLSCAFTHRPCSHPRLEGQEFCIKHILEDKNAPFKQCSYISTKNGKRCPNAAPKPEKKDGVSFCAEHVRRNALALHAQMKKTNPGPVGETLLCQLSSYAKTELGSQTPESSRSEASRILDEDSWSDGEQEPITVDQTWRGDPDSEADSIDSDQEDPLKHAGVYTAEEVALIMREKLIRLQSLYIDQFKRLQHLLKEKKRRYLHNRKVEHEALGSSLLTGPEGLLAKERENLKRLKCLRRYRQRYGVEALLHRQLKERRMLATDGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEVPCNKPVPVSLSEDPCCPLHFQLPPQMYKPEQVLSVPDDLEAGPMDLYLSAAELQPTESLPLEFSDDLDVVGDGMQCPPSPLLFDPSLTLEDHLVKEIAEDPVDILGQMQMAGDGCRSQGSRNSEKASAPLSQSGLATANGKPEPTSIS", "length": 492 }, "evidence": [ { "id": "A0A4X1TB16", "url": "https://omabrowser.org/oma/group/A0A4X1TB16/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16" } ], "pmid": "" }, { "name": "NSL complex", "id": "GO:0044545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044545", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TB16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TB16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TB16" }, { "id": "PF13891", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13891" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KANL2-like probable zinc-finger", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 92, "start_aa": "Cys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 313, "end_pos": 315 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TE28-1", "uniprot_ac": "A0A4X1TE28", "uniprot_id": "A0A4X1TE28_PIG", "mass": { "chemical_mass": 66333.0, "monoisotopic_mass": 66333.0 }, "refseq": { "ac": "NP_001229962", "name": "zinc finger-containing ubiquitin peptidase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229962" }, "gene_names": [ { "name": "ZUP1", "type": "recommended", "evidence": [ { "id": "A0A4X1TE28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28" } ] }, { "name": "ZUFSP", "type": "synonym", "evidence": [ { "id": "NP_001229962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229962" } ] }, { "name": "ZUP1", "type": "synonym", "evidence": [ { "id": "NP_001229962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229962" } ] } ], "protein_names": [ { "name": "Zinc finger-containing ubiquitin peptidase 1", "type": "recommended", "evidence": [ { "id": "A0A4X1TE28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "A0A4X1TE28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28/entry#names_and_taxonomy" } ] }, { "name": "Lys-63-specific deubiquitinase ZUFSP", "type": "synonym", "evidence": [ { "id": "A0A4X1TE28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger with UFM1-specific peptidase domain protein", "type": "synonym", "evidence": [ { "id": "A0A4X1TE28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28/entry#names_and_taxonomy" } ] }, { "name": "zinc finger with UFM1 specific peptidase domain", "type": "synonym", "evidence": [ { "id": "NP_001229962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229962" } ] }, { "name": "zinc finger-containing ubiquitin peptidase 1", "type": "synonym", "evidence": [ { "id": "NP_001229962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229962" } ] } ], "function": [ { "annotation": "Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains. Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage. Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE28", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28#function" }, { "database": "UniProtKB", "id": "ARBA00045669", "url": "https://www.uniprot.org/uniprotkb/ARBA00045669#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE28", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZUP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28", "locus": { "chromosome": "1", "start_pos": 44961145, "end_pos": 44939951, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004263", "url": "https://www.ensembl.org/id/ENSSSCG00000004263" } ] } } ], "crossref": [ { "id": "A0A4X1TE28", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TE28", "database": "AlphaFoldDB", "categories": [] }, { "id": "100156556", "url": "https://www.ncbi.nlm.nih.gov/gene/100156556", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156556", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156556", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGSKAWI", "url": "https://omabrowser.org/oma/group/CGSKAWI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TE28", "url": "https://www.orthodb.org/?gene=A0A4X1TE28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403:SF82", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403:SF82", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07910", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07910", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001229962", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229962", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TC13", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TC13-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TE28", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TE28-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSCDICGETVTSEPDMKAHLIVHMEDDVICPFCKLSGVSYDEMCFHIETAHFEQNELERNIERINSVQYGTSDNRTDSTLQCRMEVNSSIHSACASNHPKILAQSLPKEGSLKHKGFHSENVTESRKFLKSKEKQSDLTKIKGSIYETMYSPPECPFCGKIEDCSQDMETHVKTKHTNLLDTPLEDCDEPLYDCPMCGLICTNYHILQEHVDLHLEESGFGQGMDRVQCSRDLELAQQLQQEEDRKRRSEESRQEMEEFRKLQRQYGLDNSGGYKQQQLRNMEIEVNRGKMHPSEFHRRKADMMESLAIGIDDGKTKTSGIMEALYRYYQNAATDVRRVWLSTVVDHFHSSFGDKGWGCGYRNFQMLLSSLLQNDAYGDCLKDMSVPCIPKIQSMIEDAWKEGFDPQGASQLNNRLQGTKAWIGACEVYTLLTSLRIKCRIIDFHKSTGPLGTHPRLFEWILNYYSSEREGSPKVVCTSKPPIYLQHQGHSRTIVGIEERKNRTLCLLIFDPGWPSRDMQKFLKQDMEASSLKQLRKFVGNLKHKQYQIVAVEGVLSSEEKIARRQASQVFTAEKIP", "length": 578, "header": "tr|A0A4X1TE28-1|A0A4X1TE28_PIG Isoform 1 of Zinc finger-containing ubiquitin peptidase 1 OS=Sus scrofa OX=9823 GN=ZUP1 PE=3 SV=1 CANONICAL=A0A4X1TE28-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TC13-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28/entry#A0A4X1TC13-1", "sequence": { "sequence": "MLSCDICGETVTSEPDMKAHLIVHMEDDVICPFCKLSGVSYDEMCFHIETAHFEQNELERNIERINSVQYGTSDNRTDSTLQCRMEVNSSIHSACASNHPKILAQSLPKEGSLKHKGFHSENVTESRKFLKSKEKQSDLTKIKGSIYETMYSPPECPFCGKIEDCSQDMETHVKTKHTNLLDTPLEDCDEPLYDCPMCGLICTNYHILQEHVDLHLEESGFGQGMDRVQCSRDLELAQQLQQEEDRKRRSEESRQEMEEFRKLQELWKHFTGITRMLPQM", "length": 280, "header": "tr|A0A4X1TC13-1|A0A4X1TC13_PIG Computationally mapped isoform of Zinc finger containing ubiquitin peptidase 1 OS=Sus scrofa OX=9823 GN=ZUP1 PE=4 SV=1 CANONICAL=A0A4X1TE28-1" }, "locus": { "chromosome": "1", "start_pos": 44953330, "end_pos": 44941510, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004712.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004712.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004604.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004604.4" } ] } }, { "isoform_ac": "A0A4X1TE28-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28/entry#A0A4X1TE28-1", "sequence": { "sequence": "MLSCDICGETVTSEPDMKAHLIVHMEDDVICPFCKLSGVSYDEMCFHIETAHFEQNELERNIERINSVQYGTSDNRTDSTLQCRMEVNSSIHSACASNHPKILAQSLPKEGSLKHKGFHSENVTESRKFLKSKEKQSDLTKIKGSIYETMYSPPECPFCGKIEDCSQDMETHVKTKHTNLLDTPLEDCDEPLYDCPMCGLICTNYHILQEHVDLHLEESGFGQGMDRVQCSRDLELAQQLQQEEDRKRRSEESRQEMEEFRKLQRQYGLDNSGGYKQQQLRNMEIEVNRGKMHPSEFHRRKADMMESLAIGIDDGKTKTSGIMEALYRYYQNAATDVRRVWLSTVVDHFHSSFGDKGWGCGYRNFQMLLSSLLQNDAYGDCLKDMSVPCIPKIQSMIEDAWKEGFDPQGASQLNNRLQGTKAWIGACEVYTLLTSLRIKCRIIDFHKSTGPLGTHPRLFEWILNYYSSEREGSPKVVCTSKPPIYLQHQGHSRTIVGIEERKNRTLCLLIFDPGWPSRDMQKFLKQDMEASSLKQLRKFVGNLKHKQYQIVAVEGVLSSEEKIARRQASQVFTAEKIP", "length": 578, "header": "tr|A0A4X1TE28-1|A0A4X1TE28_PIG Isoform 1 of Zinc finger-containing ubiquitin peptidase 1 OS=Sus scrofa OX=9823 GN=ZUP1 PE=3 SV=1 CANONICAL=A0A4X1TE28-1" }, "locus": { "chromosome": "1", "start_pos": 44961126, "end_pos": 44941510, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061721.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061721.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035451.3", "url": "https://www.ensembl.org/id/ENSSSCP00000035451.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE28", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156556", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156556", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YPM5-1", "protein_name": "Zinc finger-containing ubiquitin peptidase 1", "gene_name": "ZUFSP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSVCGICGQVLPSEAAARRHVNRAHPDRQPRCPLCSAAASGYEELRQHVEAAHPEPQPLPRARSPELECPFCGEVAGRQLEAHVRARHERLLGADTENVEQLYECPICGLTCTDIRILEEHVDLHLEEHSFPEGGSSGDLELAQQLQSEEDKQQRLEEEKREKEEFKKLQRQYGLDSSGGYKKQFLNNMEREVNRGRMQPFEYHKRKADMMECLAFGIDDGKTKTSGITEALCKYYQNENKDVRRVWLSAGVDHFHSSLGDKGWGCGYRNFQMLLSSLLQNSLYNDCLRDIALIPSIPKIQSMIEDAWKEGFDPHGASHFNNRLCGSKAWIGACEIYSLLTSLRIKCQIIDFHKPTGPTGTHPRLFEWILRYYSTDNEGAAKVVCTSRPPVYLQHQGHSRTVVGIEEKKNKALCLLLFDPGCPSQEMQKLLKLSSDGTSLKLLRKFMGSLKEKQYQIVTVDGVLTLEEKTARCLASRVLTSEKIP", "length": 485 }, "evidence": [ { "id": "A0A4X1TE28", "url": "https://omabrowser.org/oma/group/A0A4X1TE28/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3I567-1", "protein_name": "Zinc finger-containing ubiquitin peptidase 1", "gene_name": "Zup1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLSCDICGETVTSEPDMKAHLVVHMESEVTCPFCKLSGINYDEMCFHIETAHFEQNTPERNFERLNAIQYENPDSKNTTLQSTTEVNSSIHSACASNFPKNSSHHLPKDGTLKHEAFHTESITESRKCLKSPEKQSGLSVVQGSIYETTYSPPECPFCGKIEERSQDMEMHVKTEHASLLETPPEDCHQPLYDCPMCGLICTNYHILQEHVDLHLDESSFQQGMDRVQCSGDRELAEQLQQEEDRKRKSEESRQEREEFQKLQRQYGLDNSGGYKQQQLRHMEIEVNRGRMHPSEFHSRKADMMESIAIGIDDGKTKTSGIIEALHRYYQNIATDVRCVWLSTMVDHFHSSFGDKGWGCGYRNFQMLLSSLLQNDVYGDCLKGMSIPCIPKIQSMIEDAWKEGFDPQGACQLNNKLQGTKAWIGACEIYTLLTSLRVKCRIIDFHKSTGPSGTHPRLFEWILNYYSSEREGNSKVVCTSKPPVYLQHQGHSRTIVGIEERKNRTLCLLVFDPGCPSREMQKLLKQDIEAGSLRQLRKSVGNLKHKQYQIVAVEGVLSPEEKVARKQASQVFTAEKIP", "length": 577 }, "evidence": [ { "id": "A0A4X1TE28", "url": "https://omabrowser.org/oma/group/A0A4X1TE28/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3T9Z9-1", "protein_name": "Zinc finger-containing ubiquitin peptidase 1", "gene_name": "Zup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSCNICGETVNSEPDMKAHLIVHMENEIICPFCKLSGINYNEICFHIETVHFEQNAPEKNSEKLAAVQYGHSDRKNTNLQSTAEVTSGIHSACASSFPKESSESLPKDRTVKHEAFYTENITESRKYQKSREKKPGLSEAQGSIYETTYSPPECPFCGKIEGCSQDMEIHVKTKHASLLESPLKDCHQPLYDCPMCGLVCTNYHILQEHVDLHLEESSFQQGMDRVQCSSDRELAHRLQQEEDRKRKSEESRQEREEFQKLQRQYGLDNSGGYKQQQLRHMELEVNRGRMHPSEFHSRKADMLESIAIGIDDGKTKTSGIIEALHRYYQNTATDVRCVWLSTVVDHFHSSFGDKGWGCGYRNFQMLLSSLLQSDVYGDCLKGMAVPCIPKIQSMIEDAWNEGFDPQGASQLNNKLQGTKAWIGACEIYTLLTSLRVKCRIIDFHKSTGPLGTHPRLFEWILNYYSSETEGTPKIVCTSKPPIYLQHQGHSRTVVGIEEKKNRTLCLLVFDPGCPSREMQKLLKQDMEASSLRQLRKSVGNLKHKQYQIVAVEGVLSPEEKVARKQASQVFTAEKIP", "length": 577 }, "evidence": [ { "id": "A0A4X1TE28", "url": "https://omabrowser.org/oma/group/A0A4X1TE28/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5U2S3-1", "protein_name": "Zinc finger-containing ubiquitin peptidase 1", "gene_name": "Zup1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCDICGETVTSEPDRKAHLIVHMENEIICPFCKLSGINYNEMCFHIETAHFEQTTPEKSFETLAAVQYENSDLGNTKLHSTVEVTSGIHSACASNFPKESSESLSKDRTLKQEAFYTESVAESRKYQKSREKQSGLSEAQGSIYETTYSPPECPFCGRIERYSQDMEIHVKTKHASLLESPLEDCHQPLYDCPMCGLVCTNYHILQEHVDLHLEESSFQQGMDRVQCSSDRELAHQLQQEEERKRKSEESRQEREEFQKLQRQYGLDNSGGYKQQQLRHMELEVTRGRMHPSEFHSRKADMLESIAVGIDDGKTKTSGIIEALHRYYQNIATDVRCVWLSTVVDHFHSSFGDKGWGCGYRNFQMLLSSLLQNEVYSDCLKGMSVPCIPKIQSMIEDAWNEGFDPQGASQLNNKLQGTKAWIGACEIYTLLTSLKVKCRIIDFHKSTGPSGTHPRLFEWILNYYSSETEGAPKVVCTSKPPVYLQHQGHSRTVVGIEERKNRTLCLLIFDPGCPSREMQKLLKQDMEAGSLRQLRKCVGNLKHKQYQIVAVEGILSPEERAARKQASQVFTAEKIP", "length": 577 }, "evidence": [ { "id": "A0A4X1TE28", "url": "https://omabrowser.org/oma/group/A0A4X1TE28/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96AP4-1", "protein_name": "Zinc finger-containing ubiquitin peptidase 1", "gene_name": "ZUP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSCNICGETVTSEPDMKAHLIVHMESEIICPFCKLSGVNYDEMCFHIETAHFEQNTLERNFERINTVQYGTSDNKKDNTLQCGMEVNSSILSGCASNHPKNSAQNLTKDSTLKHEGFYSENLTESRKFLKSREKQSSLTEIKGSVYETTYSPPECPFCGKIEEHSEDMETHVKTKHANLLDIPLEDCDQPLYDCPMCGLICTNYHILQEHVDLHLEENSFQQGMDRVQCSGDLQLAHQLQQEEDRKRRSEESRQEIEEFQKLQRQYGLDNSGGYKQQQLRNMEIEVNRGRMPPSEFHRRKADMMESLALGFDDGKTKTSGIIEALHRYYQNAATDVRRVWLSSVVDHFHSSLGDKGWGCGYRNFQMLLSSLLQNDAYNDCLKGMLIPCIPKIQSMIEDAWKEGFDPQGASQLNNRLQGTKAWIGACEVYILLTSLRVKCHIVDFHKSTGPLGTHPRLFEWILNYYSSEGEGSPKVVCTSKPPIYLQHQGHSRTVIGIEEKKNRTLCLLILDPGCPSREMQKLLKQDIEASSLKQLRKSMGNLKHKQYQILAVEGALSLEEKLARRQASQVFTAEKIP", "length": 578 }, "evidence": [ { "id": "A0A4X1TE28", "url": "https://omabrowser.org/oma/group/A0A4X1TE28/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE28", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE28", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE28", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE28", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE28", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE28", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE28", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE28", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TE28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE28" }, { "id": "PS00028", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 24, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 503, "end_pos": 505 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TC89-1", "uniprot_ac": "A0A4X1TC89", "uniprot_id": "A0A4X1TC89_PIG", "mass": { "chemical_mass": 45185.0, "monoisotopic_mass": 45185.0 }, "refseq": { "ac": "XP_020920659", "name": "DNA/RNA-binding protein KIN17 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920659" }, "gene_names": [ { "name": "KIN", "type": "recommended", "evidence": [ { "id": "A0A4X1TC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ] }, { "name": "KIN", "type": "synonym", "evidence": [ { "id": "XP_020920659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920659" } ] } ], "protein_names": [ { "name": "DNA/RNA-binding protein KIN17", "type": "recommended", "evidence": [ { "id": "A0A4X1TC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89/entry#names_and_taxonomy" } ] }, { "name": "Binding to curved DNA", "type": "synonym", "evidence": [ { "id": "A0A4X1TC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89/entry#names_and_taxonomy" } ] }, { "name": "DNA/RNA-binding protein KIN17 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020920659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920659" } ] } ], "function": [ { "annotation": "Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo. Binds via its C-terminal domain to RNA in vitro.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89#function" }, { "database": "UniProtKB", "id": "ARBA00054469", "url": "https://www.uniprot.org/uniprotkb/ARBA00054469#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KIN", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89", "locus": { "chromosome": "10", "start_pos": 63631001, "end_pos": 63599632, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000033095", "url": "https://www.ensembl.org/id/ENSSSCG00000033095" } ] } } ], "crossref": [ { "id": "A0A4X1TC89", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TC89", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110255716", "url": "https://www.ncbi.nlm.nih.gov/gene/110255716", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019447", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019447", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110255716", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255716", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMTDFIE", "url": "https://omabrowser.org/oma/group/RMTDFIE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TC89", "url": "https://www.orthodb.org/?gene=A0A4X1TC89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12805", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12805", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12805:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12805:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18131", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18131", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25095", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25095", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8876725", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8876725", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020920659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920659", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TC89-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIQEQVRRGLEGKEQEAPIFTELSRENEEEKVTFNLNKGACSSAAASSKSSSLGPSALKTMGSTASVKRKESSQSSAQSKEKKKKKSALDEIMEIEEEKKRTARTDHWLQPEIIVKIITKKLGEKYHKKKGVVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNVGTLESINEKTFSATVVIETGPLKGRRVEGIQYEDISKLA", "length": 392, "header": "tr|A0A4X1TC89-1|A0A4X1TC89_PIG Isoform 1 of DNA/RNA-binding protein KIN17 OS=Sus scrofa OX=9823 GN=KIN PE=3 SV=1 CANONICAL=A0A4X1TC89-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TC89-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89/entry#A0A4X1TC89-1", "sequence": { "sequence": "MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIQEQVRRGLEGKEQEAPIFTELSRENEEEKVTFNLNKGACSSAAASSKSSSLGPSALKTMGSTASVKRKESSQSSAQSKEKKKKKSALDEIMEIEEEKKRTARTDHWLQPEIIVKIITKKLGEKYHKKKGVVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNVGTLESINEKTFSATVVIETGPLKGRRVEGIQYEDISKLA", "length": 392, "header": "tr|A0A4X1TC89-1|A0A4X1TC89_PIG Isoform 1 of DNA/RNA-binding protein KIN17 OS=Sus scrofa OX=9823 GN=KIN PE=3 SV=1 CANONICAL=A0A4X1TC89-1" }, "locus": { "chromosome": "10", "start_pos": 63628998, "end_pos": 63599691, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057280.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057280.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045257.1", "url": "https://www.ensembl.org/id/ENSSSCP00000045257.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110255716", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255716", "resource": "KEGG Pathway" }, { "id": "R-SSC-8876725", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8876725", "resource": "Reactome", "description": "Protein methylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XK22-1", "protein_name": "DNA/RNA-binding protein KIN17", "gene_name": "KIN", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFLNYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQQEQERKKKQDLDDEEKTAKFIEQQVRRGLEGKELEEPVYTELNRENEEEKVAFNLNKGASTSVAASSKTSSILGPSALKMAEGAVKRKESAHSSGQSKEKKKKSALDEIMELEEEKKRTSRTDYWLQPEIIVKIVTKKLGEKYHKKKAVVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKKVMVLNGGYRGNEGILESINEKKFSATIIIDSGPLKGRRVEGIQYEDISKLA", "length": 390 }, "evidence": [ { "id": "A0A4X1TC89", "url": "https://omabrowser.org/oma/group/A0A4X1TC89/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0L225-1", "protein_name": "DNA/RNA-binding protein KIN17", "gene_name": "Kin", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVRRGLEGKEQETPVFTELSRENDEEKVTFNLNKGAGSSAGATTSKSSSLGPSALKMLGSTASVRRKESSQSSAQPAKKKKKSALDEIMEIEEEKKRTARTDSWLQPGIIVKIITKKLGEKYHKKKGVVKEVIDRYTAVVKMTDSGDRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRLEEPRTEPRTLHLLGKRTTAELNPQPKTSIF", "length": 410 }, "evidence": [ { "id": "A0A4X1TC89", "url": "https://omabrowser.org/oma/group/A0A4X1TC89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GR62-1", "protein_name": "DNA/RNA-binding protein KIN17", "gene_name": "Kin", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVRRGLEGKEQETPVFTELSRENDEEKVTFNLNKGAGSSAVATSSKSGSLGPSALKTLGSASSMRRKESSQSSAQPAKKKKKSALDEIMELEEEKKRTARTDSWLQPGIIVKIITKKLGEKYHKKKGVVKEVIDRYTAVVKMIDSGDRLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRVEGIQYEDISKLA", "length": 392 }, "evidence": [ { "id": "A0A4X1TC89", "url": "https://omabrowser.org/oma/group/A0A4X1TC89/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60870-1", "protein_name": "DNA/RNA-binding protein KIN17", "gene_name": "KIN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVRRGLEGKEQEVPTFTELSRENDEEKVTFNLSKGACSSSGATSSKSSTLGPSALKTIGSSASVKRKESSQSSTQSKEKKKKKSALDEIMEIEEEKKRTARTDYWLQPEIIVKIITKKLGEKYHKKKAIVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRVEGIQYEDISKLA", "length": 393 }, "evidence": [ { "id": "A0A4X1TC89", "url": "https://omabrowser.org/oma/group/A0A4X1TC89/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55D16-1", "protein_name": "KIN17-like protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKGDALTPKQIANKIKAKGLQRLRWYCQLCEKQCRDENGFKCHISSESHMRQMEVFSNKSSFIVSQYSKEFEEDFLRIMSRQFINSRVPANQVYAEYIKDRHHIHMNATEWTSLTEFVKYLGKTSKCEVEETPKGWFIRYINRDPEYVMRKVSEEKKEKAELNEEERQRLQIEKQIKELNKNKIEQDEIKPTELSKEDLEKMSLLELNIKSTTNTTTTTTNTTTTTTNKNIFDKLKTNDNNSSNNNYNDQTNPKPYAKKMSAIEEIMFKEKEKERQQKEKLEFEKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLNSNNNNNEEKPWIIKDIVIKIIDKELANGKYFKQKGYIVSVENEFLAKVKLLDSGDILKIDQTFLETVIPQIGSTVIIVNGKYRGKEATIKNVNFDDFNAKLYIKDNDITITLPYESFSKQY", "length": 445 }, "evidence": [ { "id": "A0A4X1TC89", "url": "https://omabrowser.org/oma/group/A0A4X1TC89/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8K339-1", "protein_name": "DNA/RNA-binding protein KIN17", "gene_name": "Kin", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVRRGLEGKEQETPVFTELSRENEEEKVTFNLNKGAGGSAGATTSKSSSLGPSALKLLGSAASGKRKESSQSSAQPAKKKKSALDEIMELEEEKKRTARTDAWLQPGIVVKIITKKLGEKYHKKKGVVKEVIDRYTAVVKMTDSGDRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKAFSATIVIETGPLKGRRVEGIQYEDISKLA", "length": 391 }, "evidence": [ { "id": "A0A4X1TC89", "url": "https://omabrowser.org/oma/group/A0A4X1TC89/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VPH4-1", "protein_name": "Kin17", "gene_name": "kin17", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGRAEVGTPKYLANKMKSKGLQKLRWYCQMCEKQCRDENGFKCHTMSESHQRQLLLFADNPGKFLHSFSKEFSDGYMELLRRRFGTKRTSANKIYQEYIAHKEHIHMNATRWLTLSDYVKWLGRTGQVIADETEKGWFVTYIDRSPEAMERQAKADRKEKMEKDDEERMADFIEQQIKNAKAKDGEEDEGQEKFTELKREENEPLKLDIRLEKKFQPDTVLGKSALAKRPAPEAEEKVFKKPKSVAGDSQTRSVLDEIIKQEESKKERANRKDYWLHKGIVVKFISKSMGEKFFKQKAVVLDVIDRYQGKIKFLETGEKLKVDQAHLETVIPALDKPVMVVNGAYRGSEALLRKLDERRYSVSVEILHGPLKGRIVDNVQYEDISKLHGA", "length": 390 }, "evidence": [ { "id": "A0A4X1TC89", "url": "https://omabrowser.org/oma/group/A0A4X1TC89/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9ZVU5-1", "protein_name": "KIN17-like protein", "gene_name": "KIN17", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGKNDFLTPKAIANRIKAKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQMQVFGQNPTRVVDGYSEEFEQTFLDLMRRSHRFSRIAATVVYNEYINDRHHVHMNSTEWATLTEFIKHLGKTGKCKVEETPKGWFITYIDRDSETLFKERLKNKRVKSDLAEEEKQEREIQRQIERAAEKLNGGGGEGETSGNDEVVDDGDDERKKDEDLRLKSGVKVGFALGGGVKQVATGKERGESSKLLFGDEENDKVERGEKRKRSGDSGRSEKERRSALDELMKEEEKKKERMNRKDYWLFEGIIVKVMSKALAEKGYYKQKGVVKKVIDNYVGEIKMLDSKHVLRVDQKELETVLPQIGGMVKIVNGAYRGSNARLLGVDTEKFCAKVQIEKGVYDGRVIKSIEYEDICKLA", "length": 411 }, "evidence": [ { "id": "A0A4X1TC89", "url": "https://omabrowser.org/oma/group/A0A4X1TC89/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TC89", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TC89" }, { "id": "SM01253", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01253" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DNA/RNA-binding protein Kin17 WH-like", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 178, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TCW8-1", "uniprot_ac": "A0A4X1TCW8", "uniprot_id": "A0A4X1TCW8_PIG", "mass": { "chemical_mass": 38342.0, "monoisotopic_mass": 38342.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Vomeronasal type-1 receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TCW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative pheromone receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCW8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8#function" }, { "database": "UniProtKB", "id": "ARBA00003878", "url": "https://www.uniprot.org/uniprotkb/ARBA00003878#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCW8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8", "locus": {} } ], "crossref": [ { "id": "A0A4X1TCW8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TCW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RRNCCAL", "url": "https://omabrowser.org/oma/group/RRNCCAL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24062", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24062", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1TCW8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TCW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQEVIQSTRPMKTTLTNGTILGIVFLSQFVVGFIGNTYLLLLNINTLLFQSHKKKPGDFIFTHLTLVNFMTITFIGVPEILNSFGIRSFLDDVGCRAVLYIYRVNRSLSLCTTTFLSMFQACIITPNNSWWAWLKPKISTYIFPPFFFFWIMNMLIYTCVIVNAMAPNNTTTVGRTFSLTYCVGRESNTLPNAVFLGAMMARDFLCVFLMIWTTAYMVRLLLTHRKSVQYIHRTSLCPGPSPEIKATHTILALVICFVFFYSTNSCLTIYTSYQHNVKMLENITVFLSFCYPVICPFLLIKNHNRQIFLKCTFVKMRKRSPQFSSHNSLTQRS", "length": 333, "header": "tr|A0A4X1TCW8-1|A0A4X1TCW8_PIG Isoform 1 of Vomeronasal type-1 receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1TCW8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TCW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8/entry#A0A4X1TCW8-1", "sequence": { "sequence": "MQEVIQSTRPMKTTLTNGTILGIVFLSQFVVGFIGNTYLLLLNINTLLFQSHKKKPGDFIFTHLTLVNFMTITFIGVPEILNSFGIRSFLDDVGCRAVLYIYRVNRSLSLCTTTFLSMFQACIITPNNSWWAWLKPKISTYIFPPFFFFWIMNMLIYTCVIVNAMAPNNTTTVGRTFSLTYCVGRESNTLPNAVFLGAMMARDFLCVFLMIWTTAYMVRLLLTHRKSVQYIHRTSLCPGPSPEIKATHTILALVICFVFFYSTNSCLTIYTSYQHNVKMLENITVFLSFCYPVICPFLLIKNHNRQIFLKCTFVKMRKRSPQFSSHNSLTQRS", "length": 333, "header": "tr|A0A4X1TCW8-1|A0A4X1TCW8_PIG Isoform 1 of Vomeronasal type-1 receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1TCW8-1" }, "locus": { "chromosome": "2", "start_pos": 58073551, "end_pos": 58072553, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061755.1", "url": "https://www.ensembl.org/id/ENSSSCT00000061755.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036453.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036453.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCW8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E9Q235-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPSDTIFQIFLIFQFCLGVIGNSSLLMLYVYTFFFKPHLKKLIDSVFMHLTIVNMSTIMFTLLKDIMFSFRVPNFLDDVGCKAVFFSLRVSRGLSICTTSVLSTSQVITITPNNPTFVSWLKPRLSTWIFSSLLCSWIINLLIYGFMIDLVVAKTNMTLVGRGFSHGYCQRKKFGKQNSEWLFSFLIIHDFFYMSVMMWASLYMVIFLYRHRKLAQHLHSPNLSSQSSPERKATHSILFLVSCFVLTYWLNNFITFYGFNTKERNPRLEAINTILITSYPTICPFLLMKNNKVILQFTSSFSVLRMTCFQSSLPG", "length": 316 }, "evidence": [ { "id": "A0A4X1TCW8", "url": "https://omabrowser.org/oma/group/A0A4X1TCW8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5J3M8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r59", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPSDTIIQIFLIFQFCLGILGNSALLLLYIYTFVFRPHYKKLIDSVCIHLTIVNILMIVFLLTKDIMLSFGAHNFLDDIGCKAVLFSFRVSRGLSICSTCVLSTFQVITITSSNSKWACFKARLSTWTFSSLLCSWLINLLIYGFMLDMVIAKTNNTLVGHGYTDGLCQNKLMGNHNSGSFLSIVTIYDLFFCTIMMCASLYMVAFLYRHWEGAQHLRSPNLSFQSSPECKATHSILSLVSCFVLTYWLNNSVTLYGFYSNDKFPKLGSINSLLMTSYPTICPFLLMKNNKVILQFISSFSVLRMTCFQSLLHG", "length": 315 }, "evidence": [ { "id": "A0A4X1TCW8", "url": "https://omabrowser.org/oma/group/A0A4X1TCW8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCW8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to pheromone", "id": "GO:0019236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019236", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCW8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8" } ], "pmid": "" }, { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCW8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pheromone binding", "id": "GO:0005550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005550", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCW8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8" } ], "pmid": "" }, { "name": "pheromone receptor activity", "id": "GO:0016503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016503", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCW8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TCW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCW8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 299, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 127, "end_pos": 129 }, { "start_pos": 168, "end_pos": 170 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 17, "end_pos": 19 }, { "start_pos": 282, "end_pos": 284 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TCX1-1", "uniprot_ac": "A0A4X1TCX1", "uniprot_id": "A0A4X1TCX1_PIG", "mass": { "chemical_mass": 24142.0, "monoisotopic_mass": 24142.0 }, "refseq": { "ac": "NP_001231456", "name": "peptidyl-prolyl cis-trans isomerase FKBP14 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231456" }, "gene_names": [ { "name": "FKBP14", "type": "recommended", "evidence": [ { "id": "A0A4X1TCX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1" } ] }, { "name": "FKBP14", "type": "synonym", "evidence": [ { "id": "NP_001231456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231456" } ] } ], "protein_names": [ { "name": "peptidylprolyl isomerase", "type": "recommended", "evidence": [ { "id": "A0A4X1TCX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1/entry#names_and_taxonomy" } ] }, { "name": "5.2.1.8", "type": "synonym", "evidence": [ { "id": "A0A4X1TCX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1/entry#names_and_taxonomy" } ] }, { "name": "FK506 binding protein 14", "type": "synonym", "evidence": [ { "id": "NP_001231456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231456" } ] }, { "name": "peptidyl-prolyl cis-trans isomerase FKBP14 precursor", "type": "synonym", "evidence": [ { "id": "NP_001231456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231456" } ] }, { "name": "peptidyl-prolyl cis-trans isomerase FKBP14", "type": "synonym", "evidence": [ { "id": "NP_001231456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231456" } ] } ], "function": [ { "annotation": "PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4-hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1#function" }, { "database": "UniProtKB", "id": "ARBA00059888", "url": "https://www.uniprot.org/uniprotkb/ARBA00059888#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FKBP14", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1", "locus": { "chromosome": "18", "start_pos": 42913609, "end_pos": 42903100, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037575", "url": "https://www.ensembl.org/id/ENSSSCG00000037575" } ] } } ], "crossref": [ { "id": "A0A4X1TCX1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TCX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100514551", "url": "https://www.ncbi.nlm.nih.gov/gene/100514551", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514551", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514551", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TCX1", "url": "https://www.orthodb.org/?gene=A0A4X1TCX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46222", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46222", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46222:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46222:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00254", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00254", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231456", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231456", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TCX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TCX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0V882", "url": "https://www.uniprot.org/uniprotkb/A0A8D0V882", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0V882-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0V882-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLFLWNAVLTLLVTSSSGALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKVYLKKEFEKHGAVVNESHHDVLVEDIFDKEDEDKDGFISAREFTYKHDEL", "length": 211, "header": "tr|A0A4X1TCX1-1|A0A4X1TCX1_PIG Isoform 1 of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=FKBP14 PE=4 SV=1 CANONICAL=A0A4X1TCX1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TCX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1/entry#A0A4X1TCX1-1", "sequence": { "sequence": "MRLFLWNAVLTLLVTSSSGALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKVYLKKEFEKHGAVVNESHHDVLVEDIFDKEDEDKDGFISAREFTYKHDEL", "length": 211, "header": "tr|A0A4X1TCX1-1|A0A4X1TCX1_PIG Isoform 1 of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=FKBP14 PE=4 SV=1 CANONICAL=A0A4X1TCX1-1" }, "locus": { "chromosome": "18", "start_pos": 42911804, "end_pos": 42903273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057687.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057687.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036519.3", "url": "https://www.ensembl.org/id/ENSSSCP00000036519.3" } ] } }, { "isoform_ac": "A0A8D0V882-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1/entry#A0A8D0V882-1", "sequence": { "sequence": "MRLFLWNAVLTLLVTSSSGALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHST", "length": 66, "header": "tr|A0A8D0V882-1|A0A4X1TCX1_PIG Computationally mapped isoform of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=FKBP14 PE=4 SV=1 CANONICAL=A0A4X1TCX1-1" }, "locus": { "chromosome": "18", "start_pos": 42903870, "end_pos": 42903673, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099238.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099238.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074990.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074990.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0V882", "url": "https://www.uniprot.org/uniprotkb/A0A8D0V882" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514551", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514551", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TCX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TCX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 135, "end_pos": 170, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TCX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TCX1" }, { "id": "PS50059", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50059" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPIase FKBP-type", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 135, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 176, "end_pos": 178 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TD48-1", "uniprot_ac": "A0A4X1TD48", "uniprot_id": "A0A4X1TD48_PIG", "mass": { "chemical_mass": 23382.0, "monoisotopic_mass": 23382.0 }, "refseq": { "ac": "XP_003128703", "name": "rRNA-processing protein FCF1 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128703" }, "gene_names": [ { "name": "FCF1", "type": "recommended", "evidence": [ { "id": "A0A4X1TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48" } ] }, { "name": "FCF1", "type": "synonym", "evidence": [ { "id": "XP_003128703", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128703" } ] } ], "protein_names": [ { "name": "rRNA-processing protein FCF1 homolog", "type": "recommended", "evidence": [ { "id": "A0A4X1TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48/entry#names_and_taxonomy" } ] }, { "name": "rRNA-processing protein FCF1 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003128703", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128703" } ] } ], "function": [ { "annotation": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD48", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48#function" }, { "database": "UniProtKB", "id": "ARBA00035000", "url": "https://www.uniprot.org/uniprotkb/ARBA00035000#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD48", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FCF1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48", "locus": { "chromosome": "7", "start_pos": 97958624, "end_pos": 97940954, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000039202", "url": "https://www.ensembl.org/id/ENSSSCG00000039202" } ] } } ], "crossref": [ { "id": "A0A4X1TD48", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TD48", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09864", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09864", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524688", "url": "https://www.ncbi.nlm.nih.gov/gene/100524688", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037503", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037503", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524688", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524688", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GMMDCLL", "url": "https://omabrowser.org/oma/group/GMMDCLL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TD48", "url": "https://www.orthodb.org/?gene=A0A4X1TD48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003128703", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128703", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TD48", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TD48-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKQKKTRKYAIMKRMLSLRDQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFERLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF", "length": 198, "header": "tr|A0A4X1TD48-1|A0A4X1TD48_PIG Isoform 1 of rRNA-processing protein FCF1 homolog OS=Sus scrofa OX=9823 GN=FCF1 PE=3 SV=1 CANONICAL=A0A4X1TD48-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TD48-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48/entry#A0A4X1TD48-1", "sequence": { "sequence": "MGKQKKTRKYAIMKRMLSLRDQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFERLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF", "length": 198, "header": "tr|A0A4X1TD48-1|A0A4X1TD48_PIG Isoform 1 of rRNA-processing protein FCF1 homolog OS=Sus scrofa OX=9823 GN=FCF1 PE=3 SV=1 CANONICAL=A0A4X1TD48-1" }, "locus": { "chromosome": "7", "start_pos": 97958011, "end_pos": 97941000, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038693.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038693.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045943.1", "url": "https://www.ensembl.org/id/ENSSSCP00000045943.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD48", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524688", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524688", "resource": "KEGG Pathway" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1RUD3-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "FCF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGKQKKARKYAVMKRMISLRDHRINEKDRAKAPAKKKEDPSAIKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQRYRVALRIAKDPRFERLPCMHKGTYADDCLVQRVTQHKCYIVATVDKELKRRIRKIPGVPIMYISRHRYNIERMPDDYGAPRF", "length": 198 }, "evidence": [ { "id": "A0A4X1TD48", "url": "https://omabrowser.org/oma/group/A0A4X1TD48/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8C2MDU6-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "Fcf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGKQKKTRKYATMKRMLSLRDERLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFDRLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF", "length": 198 }, "evidence": [ { "id": "A0A4X1TD48", "url": "https://omabrowser.org/oma/group/A0A4X1TD48/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O82346-1", "protein_name": "PIN domain-like family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGKAKKPQKFAVVKKMISHKALKHYKEEVLNPNKKDLTELPRNVPSVPAGLFFSYNSTLVPPYRVLVDTNFINFSIQNKIDLEKGMRDCLYANCTPCITDCVMAELEKLGQKYRVALRIAKDPHFERLPCIHKGTYADDCLVDRVTQHKCFIVATCDRDLKRRIRKIPGVPIMYVTNRKYSIEKLPEATLGGAPRY", "length": 196 }, "evidence": [ { "id": "A0A4X1TD48", "url": "https://omabrowser.org/oma/group/A0A4X1TD48/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q05498-1", "protein_name": "rRNA-processing protein FCF1", "gene_name": "FCF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGKAKKTRKFGLVKRTLNTKKDQRLKKNQENIKTKEDPELTRNIPQVSSALFFQYNQAIKPPYQVLIDTNFINFSIQKKVDIVRGMMDCLLAKCNPLITDCVMAELEKLGPKYRIALKLARDPRIKRLSCSHKGTYADDCLVHRVLQHKCYIVATNDAGLKQRIRKIPGIPLMSVGGHAYVIEKLPDVF", "length": 189 }, "evidence": [ { "id": "A0A4X1TD48", "url": "https://omabrowser.org/oma/group/A0A4X1TD48/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q1RP75-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "Fcf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "GKQKKTRKYATMKRMLSLRDERLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFDRLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYLSNHRYNIERMPDDYGAPRF", "length": 197 }, "evidence": [ { "id": "A0A4X1TD48", "url": "https://omabrowser.org/oma/group/A0A4X1TD48/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32PD0-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "FCF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGKQKKTRKYATMKRMLSLRDQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFERLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF", "length": 198 }, "evidence": [ { "id": "A0A4X1TD48", "url": "https://omabrowser.org/oma/group/A0A4X1TD48/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55GM5-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "fcf1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARKPGLAPKKVPLQKLNKTNPNFSNRQKQIQRSKQEDEHRKKLEEIPEDNTSHMFFSYNEALVPPYHVIIDTNFINFSISHKLDIIHSLMDCLYAKCIPYISDCVAAEIERLGSKFKVALKISKDPRFQRLTCSHKGTYADDCIINRITMHRMFIVATCDADLRRRIRKIPGVPIVYLKGKKYTVERMPDLLQ", "length": 194 }, "evidence": [ { "id": "A0A4X1TD48", "url": "https://omabrowser.org/oma/group/A0A4X1TD48/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9CTH6-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "Fcf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKQKKTRKYATMKRMLSLRDERLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKFRVALRIAKDPRFDRLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYLSNHRYNIERMPDDYGAPRF", "length": 198 }, "evidence": [ { "id": "A0A4X1TD48", "url": "https://omabrowser.org/oma/group/A0A4X1TD48/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VL75-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "Bka", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKHKKTQKVKKQRNAQLKRIIKPTDARLKDQIRVKRKKAEDPHQIKVHEATQQSSALFFQYNTQLGPPYHIVLDTNFINFSIKNKLDIVQGMMDCLYAKCIPYISDCVRAELEKLGNKYKLALRIISDPRFERLPCLHKGTYADDCLVERVRQHKCYIVATNDKDLKNRIRKIPGVPIMYVAAHKYAIERMPEAYGVKA", "length": 200 }, "evidence": [ { "id": "A0A4X1TD48", "url": "https://omabrowser.org/oma/group/A0A4X1TD48/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y324-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "FCF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKQKKTRKYATMKRMLSLRDQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFERLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF", "length": 198 }, "evidence": [ { "id": "A0A4X1TD48", "url": "https://omabrowser.org/oma/group/A0A4X1TD48/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD48", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD48", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD48", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD48", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD48" }, { "id": "SM00670", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00670" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIN", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 166, "start_aa": "Tyr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TD81-1", "uniprot_ac": "A0A4X1TD81", "uniprot_id": "A0A4X1TD81_PIG", "mass": { "chemical_mass": 25802.0, "monoisotopic_mass": 25802.0 }, "refseq": { "ac": "NP_001230308", "name": "glutathione S-transferase A4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230308" }, "gene_names": [ { "name": "GSTA4", "type": "recommended", "evidence": [ { "id": "A0A4X1TD81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81" } ] }, { "name": "GSTA4", "type": "synonym", "evidence": [ { "id": "NP_001230308", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230308" } ] } ], "protein_names": [ { "name": "glutathione transferase", "type": "recommended", "evidence": [ { "id": "A0A4X1TD81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.18", "type": "synonym", "evidence": [ { "id": "A0A4X1TD81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81/entry#names_and_taxonomy" } ] }, { "name": "glutathione S-transferase A4", "type": "synonym", "evidence": [ { "id": "NP_001230308", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230308" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GSTA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81", "locus": { "chromosome": "7", "start_pos": 46635902, "end_pos": 46656450, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002627", "url": "https://www.ensembl.org/id/ENSSSCG00000002627" } ] } } ], "crossref": [ { "id": "A0A4X1TD81", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TD81", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002627", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002627", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03208", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03208", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152951", "url": "https://www.ncbi.nlm.nih.gov/gene/100152951", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152951", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152951", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TVYNVFM", "url": "https://omabrowser.org/oma/group/TVYNVFM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TD81", "url": "https://www.orthodb.org/?gene=A0A4X1TD81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571:SF123", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571:SF123", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14497", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14497", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156590", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230308", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230308", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TD81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TD81-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S7C8", "url": "https://www.uniprot.org/uniprotkb/F1S7C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S7C8-1", "url": "https://www.uniprot.org/uniprotkb/F1S7C8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMATKPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLQKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADKHHLFGKDLKERTLIDMYVEGTLDLLELIIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEKVLRGHGQRFLVGNQLSLADIILLQTILALEEKIPNILSAFPHLQEFTVKISNIPTIKKFLEPGSKKKPPPDDIYVRTVYNIFMP", "length": 223, "header": "tr|A0A4X1TD81-1|A0A4X1TD81_PIG Isoform 1 of glutathione transferase OS=Sus scrofa OX=9823 GN=GSTA4 PE=1 SV=1 CANONICAL=A0A4X1TD81-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TD81-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81/entry#A0A4X1TD81-1", "sequence": { "sequence": "MMATKPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLQKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADKHHLFGKDLKERTLIDMYVEGTLDLLELIIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEKVLRGHGQRFLVGNQLSLADIILLQTILALEEKIPNILSAFPHLQEFTVKISNIPTIKKFLEPGSKKKPPPDDIYVRTVYNIFMP", "length": 223, "header": "tr|A0A4X1TD81-1|A0A4X1TD81_PIG Isoform 1 of glutathione transferase OS=Sus scrofa OX=9823 GN=GSTA4 PE=1 SV=1 CANONICAL=A0A4X1TD81-1" }, "locus": { "chromosome": "7", "start_pos": 46655415, "end_pos": 46636387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100869.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100869.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080881.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080881.1" } ] } }, { "isoform_ac": "A0A8W4FFQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81/entry#A0A8W4FFQ8-1", "sequence": { "sequence": "MVEIDGMKLVQTRSILHYIADKHHLFGKDLKERTLIDMYVEGTLDLLELIIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEKVLRGHGQRFLVGNQLSLADIILLQTILALEEKIPNILSAFPHLQEFTVKISNIPTIKKFLEPGSKKKPPPDDIYVRTVYNIFMP", "length": 166, "header": "tr|A0A8W4FFQ8-1|A0A4X1TD81_PIG Computationally mapped isoform of glutathione transferase OS=Sus scrofa OX=9823 GN=GSTA4 PE=1 SV=1 CANONICAL=A0A4X1TD81-1" }, "locus": { "chromosome": "7", "start_pos": 46644150, "end_pos": 46636387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100051.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100051.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078259.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078259.1" } ] } }, { "isoform_ac": "F1S7C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81/entry#F1S7C8-1", "sequence": { "sequence": "MMATKPKLHYPNGRGRMESVRWVLAAAGVEVPSLPIAVSAQISSIPGNHLLFQQVPMVEIDGMKLVQTRSILHYIADKHHLFGKDLKERTLIDMYVEGTLDLLELIIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEKVLRGHGQRFLVGNQLSLADIILLQTILALEEKIPNILSAFPHLQEFTVKISNIPTIKKFLEPGSKKKPPPDDIYVRTVYNIFMP", "length": 222, "header": "tr|F1S7C8-1|A0A4X1TD81_PIG Computationally mapped isoform of glutathione transferase OS=Sus scrofa OX=9823 GN=GSTA4 PE=1 SV=3 CANONICAL=A0A4X1TD81-1" }, "locus": { "chromosome": "7", "start_pos": 46655415, "end_pos": 46636387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002915.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002915.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002836.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002836.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S7C8", "url": "https://www.uniprot.org/uniprotkb/F1S7C8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152951", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152951", "resource": "KEGG Pathway" }, { "id": "R-SSC-156590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156590", "resource": "Reactome", "description": "Glutathione conjugation" } ], "orthologs": [ { "uniprot_canonical_ac": "O15217-1", "protein_name": "Glutathione S-transferase A4", "gene_name": "GSTA4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP", "length": 222 }, "evidence": [ { "id": "A0A4X1TD81", "url": "https://omabrowser.org/oma/group/A0A4X1TD81/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5E9G0-1", "protein_name": "Glutathione S-transferase A4", "gene_name": "GSTA4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATKPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLQKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADKHHLFGKDLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVANMAQKAIIRYFPVFEKVLRGHGQRFLVGNQLSLADIILLQTILALEEKIPNILSAFPHLQEYTVKISNIPTIKKFLEPGSKKKPPPDDIYVRTVYNIFMP", "length": 222 }, "evidence": [ { "id": "A0A4X1TD81", "url": "https://omabrowser.org/oma/group/A0A4X1TD81/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TD81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-176054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176054" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TD81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81" }, { "id": "PS50405", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50405" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST C-terminal", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 209, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TD81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TD81" }, { "id": "PS50404", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50404" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST N-terminal", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 84, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TF81-1", "uniprot_ac": "A0A4X1TF81", "uniprot_id": "A0A4X1TF81_PIG", "mass": { "chemical_mass": 15755.0, "monoisotopic_mass": 15755.0 }, "refseq": {}, "gene_names": [ { "name": "CNIH4", "type": "recommended", "evidence": [ { "id": "A0A4X1TF81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81" } ] } ], "protein_names": [ { "name": "Cornichon family AMPA receptor auxiliary protein 4", "type": "synonym", "evidence": [ { "id": "A0A4X1TF81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CNIH4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81", "locus": { "chromosome": "10", "start_pos": 12713203, "end_pos": 12688817, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000035034", "url": "https://www.ensembl.org/id/ENSSSCG00000035034" } ] } } ], "crossref": [ { "id": "A0A4X1TF81", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TF81", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000035034", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035034", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03311", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03311", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1TDE0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TDE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TF81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TF81-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TFA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TFA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUA1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8Z2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D2AAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8D2AAX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D2AAX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D2AAX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAVVFVFSLLDCCALIFLSVYFIITLSDLECDYINARSCCSKLNKWVLPELVGHTIVTVLMLISLHWFIFLLNLPVATWNIYRFIMVPSGNMGVFDPTEIHNRGQLKSHMKEAMIKLGFHLLCFFMYLYSGSKCPC", "length": 137, "header": "tr|A0A4X1TF81-1|A0A4X1TF81_PIG Isoform 1 of Cornichon family AMPA receptor auxiliary protein 4 OS=Sus scrofa OX=9823 GN=CNIH4 PE=1 SV=1 CANONICAL=A0A4X1TF81-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TDE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81/entry#A0A4X1TDE0-1", "sequence": { "sequence": "MEAVVFVFSLLDCCALIFLSVYFIITLSDLECDYINARSCCSKLNKWVLPELVGHTIVTVLMLISLHWFIFLLNLPVATWNIYRGSKCPC", "length": 90, "header": "tr|A0A4X1TDE0-1|A0A4X1TF81_PIG Computationally mapped isoform of Cornichon family AMPA receptor auxiliary protein 4 OS=Sus scrofa OX=9823 GN=CNIH4 PE=1 SV=1 CANONICAL=A0A4X1TF81-1" }, "locus": { "chromosome": "10", "start_pos": 12708887, "end_pos": 12688953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085333.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085333.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065612.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065612.1" } ] } }, { "isoform_ac": "A0A4X1TF81-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81/entry#A0A4X1TF81-1", "sequence": { "sequence": "MEAVVFVFSLLDCCALIFLSVYFIITLSDLECDYINARSCCSKLNKWVLPELVGHTIVTVLMLISLHWFIFLLNLPVATWNIYRFIMVPSGNMGVFDPTEIHNRGQLKSHMKEAMIKLGFHLLCFFMYLYSGSKCPC", "length": 137, "header": "tr|A0A4X1TF81-1|A0A4X1TF81_PIG Isoform 1 of Cornichon family AMPA receptor auxiliary protein 4 OS=Sus scrofa OX=9823 GN=CNIH4 PE=1 SV=1 CANONICAL=A0A4X1TF81-1" }, "locus": { "chromosome": "10", "start_pos": 12708887, "end_pos": 12688953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066024.3", "url": "https://www.ensembl.org/id/ENSSSCT00000066024.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040995.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040995.2" } ] } }, { "isoform_ac": "A0A4X1TFA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81/entry#A0A4X1TFA4-1", "sequence": { "sequence": "MEAVVFVFSLLDCCALIFLSVYFIITLSDLECDYINARSCCSKLNKWVLPELVGHTIVTVLMLISLHWFIFLLNLPVATWNIYRMILALIND", "length": 92, "header": "tr|A0A4X1TFA4-1|A0A4X1TFA4_PIG Computationally mapped isoform of Cornichon family AMPA receptor auxiliary protein 4 OS=Sus scrofa OX=9823 GN=CNIH4 PE=3 SV=1 CANONICAL=A0A4X1TF81-1" }, "locus": { "chromosome": "10", "start_pos": 12705253, "end_pos": 12688953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086611.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086611.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069752.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069752.1" } ] } }, { "isoform_ac": "A0A5G2QUA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81/entry#A0A5G2QUA1-1", "sequence": { "sequence": "MEAVVFVFSLLDCCALIFLSVYFIITLSDLECDYINARSCCSKLNKWVLPELVGHTIVTVLMLISLHWFIFLLNLPVATWNIYRFIMVPSGNMGVFDPTEIHNRGQLKSHMKEAMIKLGFHLLCFFMYLYRATPVAFRNCRLGVESELQLLAYTTATATATATWDLSHVCNLHCILWQHRILNPLSEARDRTHILMDTSQLGSFKLIISEGEEDITWNQVPEPDLIT", "length": 227, "header": "tr|A0A5G2QUA1-1|A0A4X1TF81_PIG Computationally mapped isoform of Cornichon family AMPA receptor auxiliary protein 4 OS=Sus scrofa OX=9823 GN=CNIH4 PE=1 SV=1 CANONICAL=A0A4X1TF81-1" }, "locus": { "chromosome": "10", "start_pos": 12710609, "end_pos": 12688953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070234.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070234.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061715.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061715.1" } ] } }, { "isoform_ac": "A0A5G2R8Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81/entry#A0A5G2R8Z2-1", "sequence": { "sequence": "TTRPDRPEQGPIRGGAGRGPAASGPQSGFDGRRGAATAAAEKEEEDGGGGVRFLAPRLLRAHLPLGWVLPELVGHTIVTVLMLISLHWFIFLLNLPVATWNIYRFIMVPSGNMGVFDPTEIHNRGQLKSHMKEAMIKLGFHLLCFFMYLYSMILALIND", "length": 159, "header": "tr|A0A5G2R8Z2-1|A0A4X1TF81_PIG Computationally mapped isoform of Cornichon family AMPA receptor auxiliary protein 4 OS=Sus scrofa OX=9823 GN=CNIH4 PE=1 SV=1 CANONICAL=A0A4X1TF81-1" }, "locus": { "chromosome": "10", "start_pos": 12705253, "end_pos": 12688817, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082382.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082382.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067074.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067074.1" } ] } }, { "isoform_ac": "A0A8D2AAX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81/entry#A0A8D2AAX6-1", "sequence": { "sequence": "MEAVVFVFSLLDCCALIFLSVYFIITLSDLECDYINARSCCSKLNKWVLPELVGHTIVTVLMLISLHWFIFLLNLPVATWNIYRFIMVPSGNMGVFDPTEIHNRGQLKSHMKEAMIKLGFHLLCFFMYLYSSVHSN", "length": 136, "header": "tr|A0A8D2AAX6-1|A0A4X1TF81_PIG Computationally mapped isoform of Cornichon family AMPA receptor auxiliary protein 4 OS=Sus scrofa OX=9823 GN=CNIH4 PE=1 SV=1 CANONICAL=A0A4X1TF81-1" }, "locus": { "chromosome": "10", "start_pos": 12710544, "end_pos": 12688953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102508.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102508.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080648.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080648.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D2AAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8D2AAX6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF81", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TDU7-1", "uniprot_ac": "A0A4X1TDU7", "uniprot_id": "A0A4X1TDU7_PIG", "mass": { "chemical_mass": 47109.0, "monoisotopic_mass": 47109.0 }, "refseq": {}, "gene_names": [ { "name": "NMUR1", "type": "recommended", "evidence": [ { "id": "A0A4X1TDU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ] } ], "protein_names": [ { "name": "Neuromedin U receptor 1", "type": "synonym", "evidence": [ { "id": "A0A4X1TDU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Receptor for the neuromedin-U and neuromedin-S neuropeptides.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H1#function" }, { "database": "UniProtKB", "id": "ARBA00003593", "url": "https://www.uniprot.org/uniprotkb/ARBA00003593#function" }, { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7#function" }, { "database": "UniProtKB", "id": "F1SMV4", "url": "https://www.uniprot.org/uniprotkb/F1SMV4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NMUR1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7", "locus": { "chromosome": "15", "start_pos": 132217223, "end_pos": 132228645, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016277", "url": "https://www.ensembl.org/id/ENSSSCG00000016277" } ] } } ], "crossref": [ { "id": "A0A4X1TDU7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TDU7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016277", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016277", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005391", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005391", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CAQGHAH", "url": "https://omabrowser.org/oma/group/CAQGHAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24243:SF109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24243:SF109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TDU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3H1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SMV4", "url": "https://www.uniprot.org/uniprotkb/F1SMV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SMV4-1", "url": "https://www.uniprot.org/uniprotkb/F1SMV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPLCLNCSILPGNGPLGARSSETCNDSRVLGPFDLEDLNLTHEELRLKYLGPQQTELFMPICVTYLLIFAVGTVGNGLTCTVILRHRAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMRRNYPFLLGTGGCYFRTLLFETVCLASVLNVTALSVERYVAVVHPLRARSVVTHAHVRRVLGVIWGLAVLCSLPNTSLHGLQQLEVPCRGTVPGSAVCTLVRPRALYNLVVQTTTLVFFCLPMATISVLYLLIGLRLRRERLLLLRQEAKGRARTSDSRRLQGLQNRNRTQVTKMLFVLVVVFGICWAPFHIDRLMWSLVSRWTGGLHVAFQYVHVLSGVFFYLGSAANPVLYSLMSSRFRDTFQEALCLGTRCRHRRPRYSSHSLSRVTVGSTLCDVGSPGSRVHPLAENGGSEGQQVTDPS", "length": 423, "header": "tr|A0A4X1TDU7-1|A0A4X1TDU7_PIG Isoform 1 of Neuromedin U receptor 1 OS=Sus scrofa OX=9823 GN=NMUR1 PE=3 SV=1 CANONICAL=A0A4X1TDU7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TDU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7/entry#A0A4X1TDU7-1", "sequence": { "sequence": "MDPLCLNCSILPGNGPLGARSSETCNDSRVLGPFDLEDLNLTHEELRLKYLGPQQTELFMPICVTYLLIFAVGTVGNGLTCTVILRHRAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMRRNYPFLLGTGGCYFRTLLFETVCLASVLNVTALSVERYVAVVHPLRARSVVTHAHVRRVLGVIWGLAVLCSLPNTSLHGLQQLEVPCRGTVPGSAVCTLVRPRALYNLVVQTTTLVFFCLPMATISVLYLLIGLRLRRERLLLLRQEAKGRARTSDSRRLQGLQNRNRTQVTKMLFVLVVVFGICWAPFHIDRLMWSLVSRWTGGLHVAFQYVHVLSGVFFYLGSAANPVLYSLMSSRFRDTFQEALCLGTRCRHRRPRYSSHSLSRVTVGSTLCDVGSPGSRVHPLAENGGSEGQQVTDPS", "length": 423, "header": "tr|A0A4X1TDU7-1|A0A4X1TDU7_PIG Isoform 1 of Neuromedin U receptor 1 OS=Sus scrofa OX=9823 GN=NMUR1 PE=3 SV=1 CANONICAL=A0A4X1TDU7-1" }, "locus": { "chromosome": "15", "start_pos": 132225313, "end_pos": 132218776, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082722.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082722.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069158.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069158.1" } ] } }, { "isoform_ac": "A0A5G2R3H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7/entry#A0A5G2R3H1-1", "sequence": { "sequence": "MTYPVPPTLGGIDLSSSLLAVTWIKPRAPPAPDRRGNTRAAPGSAGVSLPVGSLLAPRLSIDQSVLGRPPHARWVGSRLLDLAGRVGATPPRLGGSHAATFPGAVGSLSPTRIDDACVFPAHLRCPHSHHAAVRDPLCLNCSILPGNGPLGARSSETCNDSRVLGPFDLEDLNLTHEELRLKYLGPQQTELFMPICVTYLLIFAVGTVGNGLTCTVILRHRAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMRRNYPFLLGTGGCYFRTLLFETVCLASVLNVTALSVERYVAVVHPLRARSVVTHAHVRRVLGVIWGLAVLCSLPNTSLHGLQQLEVPCRGTVPGSAVCTLVRPRALYNLVVQTTTLVFFCLPMATISVLYLLIGLRLRRERLLLLRQEAKGRARTSDSRRLQGLQNRNRTQVTKMLFVLVVVFGICWAPFHIDRLMWSLVSRWTGGLHVAFQYVHVLSGVFFYLGSAANPVLYSLMSSRFRDTFQEALCLGTRCRHRRPRYSSHSLSRVTVGSTLCDVGSPGSRVHPLAENGGSEGQQVTDPS", "length": 556, "header": "tr|A0A5G2R3H1-1|A0A4X1TDU7_PIG Computationally mapped isoform of Neuromedin U receptor 1 OS=Sus scrofa OX=9823 GN=NMUR1 PE=3 SV=1 CANONICAL=A0A4X1TDU7-1" }, "locus": { "chromosome": "15", "start_pos": 132228645, "end_pos": 132218776, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074753.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074753.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071631.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071631.1" } ] } }, { "isoform_ac": "F1SMV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7/entry#F1SMV4-1", "sequence": { "sequence": "MTYPVPPTLGGIDLSSSLLAVTWIKPRAPPAPDRRGNTRAAPGSAGVSLPVGSLLAPRLSIDQSVLGRPPHARWVGSRLLDLAGRRRHGLGGSHAATFPGAVGSLSPTRIDDACVFPAHLRCPHSHHAAVRDPLCLNCSILPGNGPLGARSSETCNDSRVLGPFDLEDLNLTHEELRLKYLGPQQTELFMPICVTYLLIFAVGTVGNGLTCTVILRHRAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMRRNYPFLLGTGGCYFRTLLFETVCLASVLNVTALSVERYVAVVHPLRARSVVTHAHVRRVLGVIWGLAVLCSLPNTSLHGLQQLEVPCRGTVPGSAVCTLVRPRALYNLVVQTTTLVFFCLPMATISVLYLLIGLRLRRERLLLLRQEAKGRARTSDSRRLQGLQNRNRTQVTKMLFVLVVVFGICWAPFHIDRLMWSLVSRWTGGLHVAFQYVHVLSGVFFYLGSAANPVLYSLMSSRFRDTFQEALCLGTRCRHRRPRYSSHSLSRVTVGSTLCDVGSPGSRVHPLAENGGSEGQQVTDPS", "length": 553, "header": "tr|F1SMV4-1|F1SMV4_PIG Computationally mapped isoform of Neuromedin U receptor 1 OS=Sus scrofa OX=9823 GN=NMUR1 PE=3 SV=3 CANONICAL=A0A4X1TDU7-1" }, "locus": { "chromosome": "15", "start_pos": 132228645, "end_pos": 132218776, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017725.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017725.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017244.3", "url": "https://www.ensembl.org/id/ENSSSCP00000017244.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3H1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3H1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-SSC-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ], "pmid": "" }, { "name": "9+0 non-motile cilium", "id": "GO:0097731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097731", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "neuromedin U receptor activity", "id": "GO:0001607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ], "pmid": "" }, { "name": "neuropeptide receptor activity", "id": "GO:0008188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008188", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ], "pmid": "" }, { "name": "neuromedin U binding", "id": "GO:0042924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042924", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "smooth muscle contraction", "id": "GO:0006939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006939", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ], "pmid": "" }, { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ], "pmid": "" }, { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ], "pmid": "" }, { "name": "positive regulation of calcium-mediated signaling", "id": "GO:0050850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050850", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ], "pmid": "" }, { "name": "chloride transport", "id": "GO:0006821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006821", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TDU7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TDU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TDU7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 353, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 26, "end_pos": 28 }, { "start_pos": 288, "end_pos": 290 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TE25-1", "uniprot_ac": "A0A4X1TE25", "uniprot_id": "A0A4X1TE25_PIG", "mass": { "chemical_mass": 34317.0, "monoisotopic_mass": 34317.0 }, "refseq": { "ac": "XP_003123827", "name": "lysM and putative peptidoglycan-binding domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123827" }, "gene_names": [ { "name": "LYSMD3", "type": "recommended", "evidence": [ { "id": "A0A4X1TE25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25" } ] }, { "name": "LYSMD3", "type": "synonym", "evidence": [ { "id": "XP_003123827", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123827" } ] } ], "protein_names": [ { "name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A4X1TE25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25/entry#names_and_taxonomy" } ] }, { "name": "lysM and putative peptidoglycan-binding domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "XP_003123827", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123827" } ] } ], "function": [ { "annotation": "Essential for Golgi structural integrity.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25#function" }, { "database": "UniProtKB", "id": "ARBA00037465", "url": "https://www.uniprot.org/uniprotkb/ARBA00037465#function" }, { "database": "UniProtKB", "id": "A0A5G2R4Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Z5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LYSMD3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25", "locus": { "chromosome": "2", "start_pos": 97689376, "end_pos": 97703745, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000024193", "url": "https://www.ensembl.org/id/ENSSSCG00000024193" } ] } } ], "crossref": [ { "id": "A0A4X1TE25", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TE25", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000024193", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000024193", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519537", "url": "https://www.ncbi.nlm.nih.gov/gene/100519537", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519537", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519537", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IALQFCC", "url": "https://omabrowser.org/oma/group/IALQFCC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TE25", "url": "https://www.orthodb.org/?gene=A0A4X1TE25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20932:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20932:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003123827", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123827", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TE25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TE25-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4Z5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FNU0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FNU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FNU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FNU0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGRHQNRSYPLPGVHSSGQVHAFGNCTDSDILEEDAEVYELRSRGKEKIRRSTSRDRLDDIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLYPPKGRQASRPSSVHYLPEQQELQSANDSLSSSESAGSFLKEVDRDIEQIVKCTDTKRENLNEVVSALTTQQVRFEPDNKNIQRKDPYYGADWGIGWWTAVAIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHSGVTPPSQQREMENGIAPTKGIPFGPQDDPKLYSQDAQLPAAQHKT", "length": 306, "header": "tr|A0A4X1TE25-1|A0A4X1TE25_PIG Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 3 OS=Sus scrofa OX=9823 GN=LYSMD3 PE=4 SV=1 CANONICAL=A0A4X1TE25-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TE25-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25/entry#A0A4X1TE25-1", "sequence": { "sequence": "MAGRHQNRSYPLPGVHSSGQVHAFGNCTDSDILEEDAEVYELRSRGKEKIRRSTSRDRLDDIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLYPPKGRQASRPSSVHYLPEQQELQSANDSLSSSESAGSFLKEVDRDIEQIVKCTDTKRENLNEVVSALTTQQVRFEPDNKNIQRKDPYYGADWGIGWWTAVAIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHSGVTPPSQQREMENGIAPTKGIPFGPQDDPKLYSQDAQLPAAQHKT", "length": 306, "header": "tr|A0A4X1TE25-1|A0A4X1TE25_PIG Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 3 OS=Sus scrofa OX=9823 GN=LYSMD3 PE=4 SV=1 CANONICAL=A0A4X1TE25-1" }, "locus": { "chromosome": "2", "start_pos": 97698627, "end_pos": 97692774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047391.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047391.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044321.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044321.1" } ] } }, { "isoform_ac": "A0A5G2R4Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25/entry#A0A5G2R4Z5-1", "sequence": { "sequence": "VPRPNGTGVHSSGQVHAFGNCTDSDILEEDAEVYELRSRGKEKIRRSTSRDRLDDIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLYPPKGRQASRPSSVHYLPEQQELQSANDSLSSSESAGSFLKEVDRDIEQIVKCTDTKRENLNEVVSALTTQQVRFEPDNKNIQRKDPYYGADWGIGWWTAVAIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHSGVTPPSQQREMENGIAPTKGIPFGPQDDPKLYSQDAQLPAAQHKT", "length": 300, "header": "tr|A0A5G2R4Z5-1|A0A4X1TE25_PIG Computationally mapped isoform of LysM and putative peptidoglycan-binding domain-containing protein 3 OS=Sus scrofa OX=9823 GN=LYSMD3 PE=4 SV=1 CANONICAL=A0A4X1TE25-1" }, "locus": { "chromosome": "2", "start_pos": 97703618, "end_pos": 97692774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078223.1", "url": "https://www.ensembl.org/id/ENSSSCT00000078223.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072289.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072289.1" } ] } }, { "isoform_ac": "A0A8W4FNU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25/entry#A0A8W4FNU0-1", "sequence": { "sequence": "MIHVNQSNESAAFQGFLCLLSPPDFDIMAGRHQNRSYPLPGVHSSGQVHAFGNCTDSDILEEDAEVYELRSRGKEKIRRSTSRDRLDDIIVLTKDIQEGDTLNAIALQYCCTVSFNLILHNIAPNELFVHNTN", "length": 133, "header": "tr|A0A8W4FNU0-1|A0A4X1TE25_PIG Computationally mapped isoform of LysM and putative peptidoglycan-binding domain-containing protein 3 OS=Sus scrofa OX=9823 GN=LYSMD3 PE=4 SV=1 CANONICAL=A0A4X1TE25-1" }, "locus": { "chromosome": "2", "start_pos": 97698708, "end_pos": 97698310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091849.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091849.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081162.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081162.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 279, "start_aa": "Thr", "end_pos": 279, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr279", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FNU0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FNU0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519537", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519537", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BGG0-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "gene_name": "LYSMD3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGRHQNRSFPLPGIHSSAQVHAFGNCADSDMLEEDAEVYELRSRGKEKIRRSTSKDRLDDIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLYPPKGRQASRPSTVQYLPEQQEVLSANDSLSSTESAGSFLKEVDRDIEQIVKCTDTKRENLNEVVSALTAQQVRFEPDNKNIQRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHSGVTPPSQQREMENGIAPTKGIPFGPQDDRKLYNQDSQLPAAQHKT", "length": 306 }, "evidence": [ { "id": "A0A4X1TE25", "url": "https://omabrowser.org/oma/group/A0A4X1TE25/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HL69-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "gene_name": "Lysmd3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGRNQNRTISLPGIQASGQVHTFGNCTDNDVLEEDAEVYELRSRGKEKVRRSTSRDRLDDIIILTKDIQEGDTLNAVALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLHPLKGRQGFHPPLVPCAQGQETVAAEDSLCSSESAGSFLKEVDRDIEQIVKCTDTKKENLNEVVSALTAQQIRFEPDSRSTPRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVGSSHLHPGLTPPSQNREMENGIAPTKGIHVGQQDDHRLYRQDSQSPAAQHKT", "length": 305 }, "evidence": [ { "id": "A0A4X1TE25", "url": "https://omabrowser.org/oma/group/A0A4X1TE25/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5M836-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "gene_name": "Lysmd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRNQNRTASLAGIQASGHVHTFGNCTDNDMLEEDAEVYELRSRGKEKVRRSTSRDRLDDIVILTKDIQEGDTLNAVALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKRFSSLTETLHPLKGRQVLHPPPVPYFQEQDTVPANDSPSSSESAGSFLKEVDRDIEQIVKCTDTKKENLNEVVSALTAQQVRFEPDNKSVHRKDPYYGADWGMGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHPGLTPPSHHREMGNAIGPTKGIPVGQQDDHRLYRQDPQARD", "length": 300 }, "evidence": [ { "id": "A0A4X1TE25", "url": "https://omabrowser.org/oma/group/A0A4X1TE25/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z3D4-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "gene_name": "LYSMD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGRHQNRSFPLPGVQSSGQVHAFGNCSDSDILEEDAEVYELRSRGKEKVRRSTSRDRLDDIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLCPPKGRQTSRHSSVQYSSEQQEILPANDSLAYSDSAGSFLKEVDRDIEQIVKCTDNKRENLNEVVSALTAQQMRFEPDNKNTQRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHSKITPPSQQREMENGIVPTKGIHFSQQDDHKLYSQDSQSPAAQQET", "length": 306 }, "evidence": [ { "id": "A0A4X1TE25", "url": "https://omabrowser.org/oma/group/A0A4X1TE25/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99LE3-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 3", "gene_name": "Lysmd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGRNQNRTVSLPGIQASGHVLAFGNCTDNDMLEEDAEVYELRSRGKEKVRRSASRDRLDDIVILTKDIQEGDTLNAVALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKRFSSLTETLHPLKGRHILHPPPVPYFQEQDIVPADGSLSSSESAGSFLKEVDRDIEQIVKCTDTKKENLNEVVSALTAQQVRFEPDNKSIHRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVGSSHLHPGLTPPTQHREMENEIGPTKGIPVGQQDDHKLYRQDPQAHDAQHKT", "length": 305 }, "evidence": [ { "id": "A0A4X1TE25", "url": "https://omabrowser.org/oma/group/A0A4X1TE25/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptidoglycan binding", "id": "GO:0042834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042834", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TE25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TE25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TE25" }, { "id": "PS51782", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LysM", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 109, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 279 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 }, { "start_pos": 26, "end_pos": 28 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TEC5-1", "uniprot_ac": "A0A4X1TEC5", "uniprot_id": "A0A4X1TEC5_PIG", "mass": { "chemical_mass": 18067.0, "monoisotopic_mass": 18067.0 }, "refseq": {}, "gene_names": [ { "name": "SPACA3", "type": "recommended", "evidence": [ { "id": "A0A4X1TEC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5" } ] } ], "protein_names": [ { "name": "Sperm acrosome membrane-associated protein 3", "type": "recommended", "evidence": [ { "id": "A0A4X1TEC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TEB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEB2#function" }, { "database": "UniProtKB", "id": "ARBA00024656", "url": "https://www.uniprot.org/uniprotkb/ARBA00024656#function" }, { "database": "UniProtKB", "id": "A0A4X1TEC5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TEC5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SPACA3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5", "locus": { "chromosome": "12", "start_pos": 42046729, "end_pos": 42054946, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017726", "url": "https://www.ensembl.org/id/ENSSSCG00000017726" } ] } } ], "crossref": [ { "id": "A0A4X1TEC5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TEC5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MYCTDLL", "url": "https://omabrowser.org/oma/group/MYCTDLL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11407", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11407", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11407:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11407:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00062", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00062", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1TEB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TEB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TEC5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TEC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEARSRAPRRRLCPPGIVLLTLASLLSCLLTSGQAKVYSRCELARLLQDVGLDGFRGYSLANWVCLAYFASGFNTAAVDHEADGSTNSGIFQINSRKWCRNLNPSVPNLCQMYCSDLLNPNLKDTIICAMKIAQDPKGLGTWEAWRHHCQGKDLTDWVDGCDL", "length": 163, "header": "tr|A0A4X1TEC5-1|A0A4X1TEC5_PIG Isoform 1 of Sperm acrosome membrane-associated protein 3 OS=Sus scrofa OX=9823 GN=SPACA3 PE=3 SV=1 CANONICAL=A0A4X1TEC5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TEB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5/entry#A0A4X1TEB2-1", "sequence": { "sequence": "AESALWGRHLIRVCLAYFASGFNTAAVDHEADGSTNSGIFQINSRKWCRNLNPSVPNLCQMYCSDLLNPNLKDTIICAMKIAQDPKGLGTWEAWRHHCQGKDLTDWVDGCDL", "length": 112, "header": "tr|A0A4X1TEB2-1|A0A4X1TEC5_PIG Computationally mapped isoform of Sperm acrosome membrane-associated protein 3 OS=Sus scrofa OX=9823 GN=SPACA3 PE=3 SV=1 CANONICAL=A0A4X1TEC5-1" }, "locus": { "chromosome": "12", "start_pos": 42054946, "end_pos": 42046807, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091802.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091802.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076504.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076504.1" } ] } }, { "isoform_ac": "A0A4X1TEC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5/entry#A0A4X1TEC5-1", "sequence": { "sequence": "MEARSRAPRRRLCPPGIVLLTLASLLSCLLTSGQAKVYSRCELARLLQDVGLDGFRGYSLANWVCLAYFASGFNTAAVDHEADGSTNSGIFQINSRKWCRNLNPSVPNLCQMYCSDLLNPNLKDTIICAMKIAQDPKGLGTWEAWRHHCQGKDLTDWVDGCDL", "length": 163, "header": "tr|A0A4X1TEC5-1|A0A4X1TEC5_PIG Isoform 1 of Sperm acrosome membrane-associated protein 3 OS=Sus scrofa OX=9823 GN=SPACA3 PE=3 SV=1 CANONICAL=A0A4X1TEC5-1" }, "locus": { "chromosome": "12", "start_pos": 42050684, "end_pos": 42046807, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019293.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019293.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018781.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018781.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TEB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEB2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MUH0-1", "protein_name": "Sperm acrosome membrane-associated protein 3", "gene_name": "Spaca3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEARIRAPRRQLCPPGITWLALAYLLSCLLASSKARVFSRCELAKELNDFGLDGYRGYNLADWICLAYYTSGFNTAAVDHEADGSTNNGIFQISSRKWCKNLSPNGPNICRMYCTDLLNYDLKNSVICAMKIVQEPQGLGYWEAWRQHCQGRDLRDWVDGCEF", "length": 163 }, "evidence": [ { "id": "A0A4X1TEC5", "url": "https://omabrowser.org/oma/group/A0A4X1TEC5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A6QQ77-1", "protein_name": "Sperm acrosome membrane-associated protein 3", "gene_name": "SPACA3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAGSWAPRRWPRPPGIVLLALASVLSSLLSSGQARVYSRCELARVLQDFGLEGYRGYSLADWICLAYFASGFNTGAVDHEADGSTNSGIFQINSRKWCKNLNPNVPNLCQMYCSDLLNPNLKDTVICAMKITQEPQGLGSWEAWRHHCQGKDLSDWVDGCEL", "length": 163 }, "evidence": [ { "id": "A0A4X1TEC5", "url": "https://omabrowser.org/oma/group/A0A4X1TEC5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1M6E7-1", "protein_name": "Sperm acrosome membrane-associated protein 3", "gene_name": "Spaca3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEARSRAPRRQPCPPGITWLALAYLLSCLLASSKAKVFSRCELAKVLHDFGLEGYRGYNLADWICLAYYTSGFNTDAVDHEADGSTNNGIFQISSRKWCKNLAPNGPNLCRIYCTDLLSNDLKDSVACVMKIAQEPQGLGYWESWKHHCQGRDLSDWVDGCDF", "length": 163 }, "evidence": [ { "id": "A0A4X1TEC5", "url": "https://omabrowser.org/oma/group/A0A4X1TEC5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IXA5-1", "protein_name": "Sperm acrosome membrane-associated protein 3", "gene_name": "SPACA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSALRGAPLIRVHSSPVSSPSVSGPRRLVSCLSSQSSALSQSGGGSTSAAGIEARSRALRRRWCPAGIMLLALVCLLSCLLPSSEAKLYGRCELARVLHDFGLDGYRGYSLADWVCLAYFTSGFNAAALDYEADGSTNNGIFQINSRRWCSNLTPNVPNVCRMYCSDLLNPNLKDTVICAMKITQEPQGLGYWEAWRHHCQGKDLTEWVDGCDF", "length": 215 }, "evidence": [ { "id": "A0A4X1TEC5", "url": "https://omabrowser.org/oma/group/A0A4X1TEC5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D9X8-1", "protein_name": "Sperm acrosome membrane-associated protein 3", "gene_name": "Spaca3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGICMSMYTQVLVPVDADGDHHILWSRFYERWGSCFNPCAGLVNCLPPHSSALYLCHRMEARSRAPRRQLCPPGITWLALAYLLSCLLASSKAKVFSRCELAKEMHDFGLDGYRGYNLADWVCLAYYTSGFNTNAVDHEADGSTNNGIFQISSRRWCRTLASNGPNLCRIYCTDLLNNDLKDSIVCAMKIVQEPLGLGYWEAWRHHCQGRDLSDWVDGCDF", "length": 221 }, "evidence": [ { "id": "A0A4X1TEC5", "url": "https://omabrowser.org/oma/group/A0A4X1TEC5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lysozyme activity", "id": "GO:0003796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003796", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TEC5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fusion of sperm to egg plasma membrane involved in single fertilization", "id": "GO:0007342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007342", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TEC5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TEC5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TEC5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5" } ], "pmid": "" }, { "name": "acrosomal membrane", "id": "GO:0002080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002080", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TEC5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5" } ], "pmid": "" }, { "name": "acrosomal matrix", "id": "GO:0043159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043159", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TEC5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TEC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TEC5" }, { "id": "PS00128", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00128" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl hydrolases family 22 (GH22)", "eco_id": "ECO_0000259", "start_pos": 110, "end_pos": 128, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TF34-1", "uniprot_ac": "A0A4X1TF34", "uniprot_id": "A0A4X1TF34_PIG", "mass": { "chemical_mass": 16711.0, "monoisotopic_mass": 16711.0 }, "refseq": { "ac": "XP_020921979", "name": "lysozyme-like protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921979" }, "gene_names": [ { "name": "LYZL6", "type": "recommended", "evidence": [ { "id": "A0A4X1TF34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34" } ] }, { "name": "LYZL6", "type": "synonym", "evidence": [ { "id": "XP_020921979", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921979" } ] } ], "protein_names": [ { "name": "Lysozyme like 6", "type": "synonym", "evidence": [ { "id": "A0A4X1TF34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34/entry#names_and_taxonomy" } ] }, { "name": "lysozyme-like protein 6", "type": "synonym", "evidence": [ { "id": "XP_020921979", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921979" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF34", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LYZL6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34", "locus": { "chromosome": "12", "start_pos": 17847014, "end_pos": 17839555, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017321", "url": "https://www.ensembl.org/id/ENSSSCG00000017321" } ] } } ], "crossref": [ { "id": "A0A4X1TF34", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TF34", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100738578", "url": "https://www.ncbi.nlm.nih.gov/gene/100738578", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100738578", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738578", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EWRLHCA", "url": "https://omabrowser.org/oma/group/EWRLHCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TF34", "url": "https://www.orthodb.org/?gene=A0A4X1TF34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11407", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11407", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11407:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11407:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00062", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00062", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020921979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921979", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TF34", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TF34-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRPLLISLVSCLVAVSQASLINRCDLAKVLHQEDLDGFEGYSLSDWLCLAFVESEFNITKVNENTDGSFDYGIFQINSHYWCNDYRSHTENICQVECEELLSPNLLSIINCAKKIVSGAGGMKNWVKWRLHCAGRPLSYWMTGCHLG", "length": 148, "header": "tr|A0A4X1TF34-1|A0A4X1TF34_PIG Isoform 1 of Lysozyme like 6 OS=Sus scrofa OX=9823 GN=LYZL6 PE=3 SV=1 CANONICAL=A0A4X1TF34-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TF34-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34/entry#A0A4X1TF34-1", "sequence": { "sequence": "MTRPLLISLVSCLVAVSQASLINRCDLAKVLHQEDLDGFEGYSLSDWLCLAFVESEFNITKVNENTDGSFDYGIFQINSHYWCNDYRSHTENICQVECEELLSPNLLSIINCAKKIVSGAGGMKNWVKWRLHCAGRPLSYWMTGCHLG", "length": 148, "header": "tr|A0A4X1TF34-1|A0A4X1TF34_PIG Isoform 1 of Lysozyme like 6 OS=Sus scrofa OX=9823 GN=LYZL6 PE=3 SV=1 CANONICAL=A0A4X1TF34-1" }, "locus": { "chromosome": "12", "start_pos": 17846731, "end_pos": 17842861, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018857.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018857.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018354.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018354.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF34", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100738578", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738578", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A077S6M4-1", "protein_name": "Lysozyme-like 6", "gene_name": "Lyzl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMMRVLFICVVSCLLVVNDGSIINRCTLARILYQEDLDGFEGYSLPHWLCLAFVESKFNISKVTENADGTFDYGIFQINSRYWCNDYQSHSENFCRLDCEELLNPNLIPSIHCAKMIVSGSGGMKNWVDWRLHCLGRPLSYWLTGCRLV", "length": 149 }, "evidence": [ { "id": "A0A4X1TF34", "url": "https://omabrowser.org/oma/group/A0A4X1TF34/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75951-1", "protein_name": "Lysozyme-like protein 6", "gene_name": "LYZL6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKALLIYLVSSFLALNQASLISRCDLAQVLQLEDLDGFEGYSLSDWLCLAFVESKFNISKINENADGSFDYGLFQINSHYWCNDYKSYSENLCHVDCQDLLNPNLLAGIHCAKRIVSGARGMNNWVEWRLHCSGRPLFYWLTGCRLR", "length": 148 }, "evidence": [ { "id": "A0A4X1TF34", "url": "https://omabrowser.org/oma/group/A0A4X1TF34/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DA11-1", "protein_name": "Lysozyme-like protein 6", "gene_name": "Lyzl6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKALFICVASCLLVVNDGNIIHRCSLAKILYEEDLDGFEGYSLPDWLCLAFVESNFNISKVNENVDGSFDYGIFQINSRYWCNDYQSHSENFCHVDCQELLSPNLISTIHCAKKIVSGPGGMKNWVEWKLHCLGRPLSYWMTGCHLG", "length": 148 }, "evidence": [ { "id": "A0A4X1TF34", "url": "https://omabrowser.org/oma/group/A0A4X1TF34/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fusion of sperm to egg plasma membrane involved in single fertilization", "id": "GO:0007342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007342", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF34", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF34", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF34", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF34", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34" } ], "pmid": "" }, { "name": "sperm plasma membrane", "id": "GO:0097524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF34", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF34", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lysozyme activity", "id": "GO:0003796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003796", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF34", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TF34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF34" }, { "id": "PS00128", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00128" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl hydrolases family 22 (GH22)", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 112, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 58, "end_pos": 60 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TF52-1", "uniprot_ac": "A0A4X1TF52", "uniprot_id": "A0A4X1TF52_PIG", "mass": { "chemical_mass": 36815.0, "monoisotopic_mass": 36815.0 }, "refseq": { "ac": "XP_020940775", "name": "olfactory receptor 7A17-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940775" }, "gene_names": [ { "name": "LOC100626190", "type": "recommended", "evidence": [ { "id": "A0A4X1TF52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52" } ] }, { "name": "LOC100626190", "type": "synonym", "evidence": [ { "id": "XP_020940775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940775" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TF52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7A17-like", "type": "synonym", "evidence": [ { "id": "XP_020940775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940775" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF52", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF52", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100626190", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52", "locus": {} } ], "crossref": [ { "id": "A0A4X1TF52", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TF52", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626190", "url": "https://www.ncbi.nlm.nih.gov/gene/100626190", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626190", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626190", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMCFVST", "url": "https://omabrowser.org/oma/group/DMCFVST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TF52", "url": "https://www.orthodb.org/?gene=A0A4X1TF52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020940775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940775", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TF52", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TF52-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPGNDTGFSQFFLLGFSEEPELQLLIFGLFLSMYLITVLGNLLIILAITSDSHLHTPMYFFLSHLSFVDICFTSTTIPKMLVNIMTHTKVIIYEDCLTQMYFFLLFVQLDNFLLTVMSYDRFVAICHPLHYTVIMNPLLCGHLVLISWVIGALNSLLQSLLALRLSFCTVLEIPHFFCEFKEVIQLACSNTFLNNTVMYFAVGLFGGGPFAGICYSYSKIVSSIHGISSAQGKYKAFSTCASHLSVVSLFYCTGLGVYLSSAATHSSHSSATASVMYTVVTPMLNPFIYSLRNKDIKRSLRRFLGMAAIKGPIFLQLKKCQLFQSSKH", "length": 329, "header": "tr|A0A4X1TF52-1|A0A4X1TF52_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100626190 PE=3 SV=1 CANONICAL=A0A4X1TF52-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TF52-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52/entry#A0A4X1TF52-1", "sequence": { "sequence": "MVPGNDTGFSQFFLLGFSEEPELQLLIFGLFLSMYLITVLGNLLIILAITSDSHLHTPMYFFLSHLSFVDICFTSTTIPKMLVNIMTHTKVIIYEDCLTQMYFFLLFVQLDNFLLTVMSYDRFVAICHPLHYTVIMNPLLCGHLVLISWVIGALNSLLQSLLALRLSFCTVLEIPHFFCEFKEVIQLACSNTFLNNTVMYFAVGLFGGGPFAGICYSYSKIVSSIHGISSAQGKYKAFSTCASHLSVVSLFYCTGLGVYLSSAATHSSHSSATASVMYTVVTPMLNPFIYSLRNKDIKRSLRRFLGMAAIKGPIFLQLKKCQLFQSSKH", "length": 329, "header": "tr|A0A4X1TF52-1|A0A4X1TF52_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100626190 PE=3 SV=1 CANONICAL=A0A4X1TF52-1" }, "locus": { "chromosome": "2", "start_pos": 64213028, "end_pos": 64212042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043022.2", "url": "https://www.ensembl.org/id/ENSSSCT00000043022.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054677.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054677.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF52", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626190", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626190", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF52", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF52", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF52", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TF52", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TF52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TF52" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TFD6-1", "uniprot_ac": "A0A4X1TFD6", "uniprot_id": "A0A4X1TFD6_PIG", "mass": { "chemical_mass": 45423.0, "monoisotopic_mass": 45423.0 }, "refseq": { "ac": "XP_020957047", "name": "transmembrane protease serine 11C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957047" }, "gene_names": [ { "name": "LOC100512727", "type": "synonym", "evidence": [ { "id": "XP_020957047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957047" } ] } ], "protein_names": [ { "name": "Transmembrane protease serine", "type": "recommended", "evidence": [ { "id": "A0A4X1TFD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.-", "type": "synonym", "evidence": [ { "id": "A0A4X1TFD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protease serine 11C", "type": "synonym", "evidence": [ { "id": "XP_020957047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957047" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFD6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6", "locus": {} } ], "crossref": [ { "id": "A0A4X1TFD6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TFD6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512727", "url": "https://www.ncbi.nlm.nih.gov/gene/100512727", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512727", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512727", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EPNTKMK", "url": "https://omabrowser.org/oma/group/EPNTKMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TFD6", "url": "https://www.orthodb.org/?gene=A0A4X1TFD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020957047", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957047", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TFD6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TFD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLTGWKQIALGILMMVIAAVVIGLIVYFVTYGKTPFYYHISFKVNNIDYDSKFEKPYSQEYMDLNEKIESLINETFHGSRLRRQYIRSHVVQVSRAKGKVIIHAVLKFKSCYINNTAKFRDKIKTILQQKLKGKTGSLSIESSSFRFSDITMPIAENLLHTCCGQRTITPSGNKIAGGMDAQEGEWPWQASLQQNNVHRCGATLISNSWLVTAAHCFIKVRNPKEWNVSFGLLLSDPQIQRSVKDIIIHENYHYPAHDNDIAVVHLSSPVLYTSSIRRACLPEATYAFPPNSNVVVTGWGTLKSDGTSPNILQKGLVKIIDNKTCSSKMVYDGAITPGMLCAGFLKGRVDACQGDSGGPLVGADYKGTWFLAGIVSWGDECALPNKPGVYTRVTYYRDWIMSKTGL", "length": 407, "header": "tr|A0A4X1TFD6-1|A0A4X1TFD6_PIG Isoform 1 of Transmembrane protease serine OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1TFD6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TFD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6/entry#A0A4X1TFD6-1", "sequence": { "sequence": "MKLTGWKQIALGILMMVIAAVVIGLIVYFVTYGKTPFYYHISFKVNNIDYDSKFEKPYSQEYMDLNEKIESLINETFHGSRLRRQYIRSHVVQVSRAKGKVIIHAVLKFKSCYINNTAKFRDKIKTILQQKLKGKTGSLSIESSSFRFSDITMPIAENLLHTCCGQRTITPSGNKIAGGMDAQEGEWPWQASLQQNNVHRCGATLISNSWLVTAAHCFIKVRNPKEWNVSFGLLLSDPQIQRSVKDIIIHENYHYPAHDNDIAVVHLSSPVLYTSSIRRACLPEATYAFPPNSNVVVTGWGTLKSDGTSPNILQKGLVKIIDNKTCSSKMVYDGAITPGMLCAGFLKGRVDACQGDSGGPLVGADYKGTWFLAGIVSWGDECALPNKPGVYTRVTYYRDWIMSKTGL", "length": 407, "header": "tr|A0A4X1TFD6-1|A0A4X1TFD6_PIG Isoform 1 of Transmembrane protease serine OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1TFD6-1" }, "locus": { "chromosome": "8", "start_pos": 65551541, "end_pos": 65495311, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022585.4", "url": "https://www.ensembl.org/id/ENSSSCT00000022585.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023282.2", "url": "https://www.ensembl.org/id/ENSSSCP00000023282.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFD6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512727", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512727", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZM18-1", "protein_name": "Transmembrane protease serine", "gene_name": "Tmprss11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARGQPRRSEEPWTALRNRTECKTKIKLTKCGKITLGILTAVIAAVVIGLIAYFAACGKTPFYYHVSFKVNNIDYDSKFAKPYSQEYMDLNKRIVSLMNETFHESKLRKQYVKAHTVQVSKAKGKVVIHGVLKFKSCYKNNVEKFWDSVETILYQKLKSQTRLLIDSSSFKFSDIAMPIAEDLLNTCCGRRTITPGGHKVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCFVRSANPKDWKVSFGFLLSKPQAQRAVKSIVIHENYSYPAHNNDIAVVRLSSPVLYENNIRRACLPEATQKFPPNSDVVVTGWGTLKSDGDSPNILQKGRVKIIDNKTCNSGKAYGGVITPGMLCAGFLEGRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWISSKTGL", "length": 431 }, "evidence": [ { "id": "A0A4X1TFD6", "url": "https://omabrowser.org/oma/group/A0A4X1TFD6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BJ94-1", "protein_name": "Transmembrane protease serine", "gene_name": "LOC100140490", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSNTKMKITRCGKISLCILTMVIAILVIGLIVCFVTYGKTYFYHHISFKVNNIDYDSKFAKPYSQEYTDLNNKIISLINETFHGSRLRRQYVTSQVVQVSQAKGKVIIHIVLKFKSYYTNTSAKFRDKIETILRQKLNGKTGSLCIDSSSFRFSDIAKPMAENFLHTCCGHRKITRSGNKIAGGMDAEEGEWPWQASLQQKNVHRCGATLISNSWLVTAAHCFLKARDPKQWNVSFGLLLSDPQIQRSVKDIIIHENYHYPSHKNDIAVVRLSSPVLYTSNIRRACLPETSYAFPSNSDVVVTGWGTLKTDGTSPNILQKGLVKIIDSKICNRKVVYDGAITPGMLCAGFLEGSVDACQGDSGGPLVGEDYKGTWFLAGIVSWGDECALPNKPGVYTRVTHYRDWIMSKTGL", "length": 413 }, "evidence": [ { "id": "A0A4X1TFD6", "url": "https://omabrowser.org/oma/group/A0A4X1TFD6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q1JRP2-1", "protein_name": "Transmembrane protease serine 11C", "gene_name": "Tmprss11c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARGQPRRSEEQWTALQNRTECKTKIKLTRCGKITLGILTAVLAAVLIGLIAYFAACGKDSFYYHVSFKVNNIDYDSKFAKPYSQEYMDLNKRIVSLMNETFHESKLRKQYVKAHTVQVSKAKGKVVIHAVLKFKACYRNNVEKYWESVETTLYQKLKGQTGLLIDSSSFKFSDIAMPIAEDLLNTCCGRRTIIHRGHKVAGGQDAEEGEWPWQASLQQNSVHRCGATLISNYWLITAAHCFIRAANPKDWKVSFGFLLSKPQAPRAVKNIIIHENYSYPAHDNDIAVVRLSSPVLYESNIRRACLPEATQKFPPNSDVVVTGWGTLKSDGDSPNILQKGKVKIIDNKTCNSGKAYGGMITPGMMCAGFLKGRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTYYRDWITSKTGL", "length": 431 }, "evidence": [ { "id": "A0A4X1TFD6", "url": "https://omabrowser.org/oma/group/A0A4X1TFD6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFD6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFD6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFD6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFD6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFD6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFD6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFD6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6" } ], "pmid": "" }, { "name": "self proteolysis", "id": "GO:0097264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097264", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFD6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TFD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 176, "end_pos": 406, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TFD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFD6" }, { "id": "PS50024", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50024" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEA", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 153, "start_aa": "Thr", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1THU5-1", "uniprot_ac": "A0A4X1THU5", "uniprot_id": "A0A4X1THU5_PIG", "mass": { "chemical_mass": 57405.0, "monoisotopic_mass": 57405.0 }, "refseq": { "ac": "XP_005659910", "name": "von Willebrand factor A domain-containing protein 9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659910" }, "gene_names": [ { "name": "INTS14", "type": "recommended", "evidence": [ { "id": "A0A4X1THU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5" } ] }, { "name": "INTS14", "type": "synonym", "evidence": [ { "id": "XP_005659910", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659910" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 14", "type": "recommended", "evidence": [ { "id": "A0A4X1THU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5/entry#names_and_taxonomy" } ] }, { "name": "von Willebrand factor A domain-containing protein 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005659910", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659910" } ] }, { "name": "von Willebrand factor A domain-containing protein 9", "type": "synonym", "evidence": [ { "id": "A0A4X1THU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THU5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "INTS14", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5", "locus": { "chromosome": "1", "start_pos": 163567777, "end_pos": 163603184, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004936", "url": "https://www.ensembl.org/id/ENSSSCG00000004936" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004936", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004936", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100153401", "url": "https://www.ncbi.nlm.nih.gov/gene/100153401", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153401", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153401", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QSSVVWI", "url": "https://omabrowser.org/oma/group/QSSVVWI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1THU5", "url": "https://www.orthodb.org/?gene=A0A4X1THU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13532", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13532", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13532:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13532:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13519", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13519", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19435", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19435", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20504", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20504", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005659910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659910", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TFH7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TFH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TFI8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TFI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1THU5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1THU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1THX0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1THX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1U644", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U644", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1U644-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U644-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATHSQRSESNRFPLPFPFPSKLYIMCMANLEELQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPESFVVDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTGTSEYAGYDHNITPLQTDFSGSSTERM", "length": 518, "header": "tr|A0A4X1THU5-1|A0A4X1THU5_PIG Isoform 1 of Integrator complex subunit 14 OS=Sus scrofa OX=9823 GN=INTS14 PE=1 SV=1 CANONICAL=A0A4X1THU5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TFH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5/entry#A0A4X1TFH7-1", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATHSQRSESNRFPLPFPFPSKLYIMCMANLEELQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPESFVVDEEIDPIPKVINTEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTGTSEYAGYDHNITPLQTDFSGSSTERM", "length": 487, "header": "tr|A0A4X1TFH7-1|A0A4X1TFH7_PIG Computationally mapped isoform of Integrator complex subunit 14 OS=Sus scrofa OX=9823 GN=INTS14 PE=1 SV=1 CANONICAL=A0A4X1THU5-1" }, "locus": { "chromosome": "1", "start_pos": 163598060, "end_pos": 163569012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053541.2", "url": "https://www.ensembl.org/id/ENSSSCT00000053541.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053261.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053261.1" } ] } }, { "isoform_ac": "A0A4X1TFI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5/entry#A0A4X1TFI8-1", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQVVLVTDGCLGIGRGSLRHSLATHSQRSESNRFPLPFPFPSKLYIMCMANLEELQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPESFVVDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTGTSEYAGYDHNITPLQTDFSGSSTERM", "length": 482, "header": "tr|A0A4X1TFI8-1|A0A4X1TFI8_PIG Computationally mapped isoform of von Willebrand factor A domain-containing protein 9 OS=Sus scrofa OX=9823 GN=INTS14 PE=1 SV=1 CANONICAL=A0A4X1THU5-1" }, "locus": { "chromosome": "1", "start_pos": 163598060, "end_pos": 163569012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005447.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005447.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005312.3", "url": "https://www.ensembl.org/id/ENSSSCP00000005312.3" } ] } }, { "isoform_ac": "A0A4X1THU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5/entry#A0A4X1THU5-1", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATHSQRSESNRFPLPFPFPSKLYIMCMANLEELQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPESFVVDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTGTSEYAGYDHNITPLQTDFSGSSTERM", "length": 518, "header": "tr|A0A4X1THU5-1|A0A4X1THU5_PIG Isoform 1 of Integrator complex subunit 14 OS=Sus scrofa OX=9823 GN=INTS14 PE=1 SV=1 CANONICAL=A0A4X1THU5-1" }, "locus": { "chromosome": "1", "start_pos": 163598060, "end_pos": 163569012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057006.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057006.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056640.1", "url": "https://www.ensembl.org/id/ENSSSCP00000056640.1" } ] } }, { "isoform_ac": "A0A4X1THX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5/entry#A0A4X1THX0-1", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQLQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPESFVVDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTGTSEYAGYDHNITPLQTDFSGSSTERM", "length": 466, "header": "tr|A0A4X1THX0-1|A0A4X1THX0_PIG Computationally mapped isoform of Integrator complex subunit 14 OS=Sus scrofa OX=9823 GN=INTS14 PE=1 SV=1 CANONICAL=A0A4X1THU5-1" }, "locus": { "chromosome": "1", "start_pos": 163598060, "end_pos": 163569012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042425.2", "url": "https://www.ensembl.org/id/ENSSSCT00000042425.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055287.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055287.1" } ] } }, { "isoform_ac": "A0A5K1U644-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5/entry#A0A5K1U644-1", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQVVLVTDGCLGIGRGSLRHSLATHSQRSESNRFPLPFPFPSKLYIMCMANLEELQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPESFVVDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGKRFLPLKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTGTSEYAGYDHNITPLQTDFSGSSTERM", "length": 460, "header": "tr|A0A5K1U644-1|A0A4X1THU5_PIG Computationally mapped isoform of Integrator complex subunit 14 OS=Sus scrofa OX=9823 GN=INTS14 PE=1 SV=2 CANONICAL=A0A4X1THU5-1" }, "locus": { "chromosome": "1", "start_pos": 163598060, "end_pos": 163569012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030635.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030635.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024824.4", "url": "https://www.ensembl.org/id/ENSSSCP00000024824.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U644", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U644" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153401", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153401", "resource": "KEGG Pathway" }, { "id": "R-SSC-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HUX8-1", "protein_name": "Integrator complex subunit 14", "gene_name": "Ints14", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATQNQRSESNRFPLPFPFPSKLYVMCMANLEELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVVKCGHLTADVQVFPRPEPFVTDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTGTSEYAAYDHNITPLHTDFSGSSTERM", "length": 518 }, "evidence": [ { "id": "A0A4X1THU5", "url": "https://omabrowser.org/oma/group/A0A4X1THU5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1LWK5-1", "protein_name": "Integrator complex subunit 14", "gene_name": "ints14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVVLMDSSLSMTRPVSVEGSEEFQRKNLAVHGLTMLFEHMATNYKLEFTSLVAFSSLWELMVPFTRDYNTLQEALNNLEDYDKTCLEGALQGVSNVVQQEWGSACPCQVVLVTDGALGIGRGSLRHSLQTVKQRGEDKKFPLPFPFPSKLYIMCIANAEELQATDGMDNLEQLINLNGGDGQIYTMEGPLCLKSVQSMFGKLIDQAYSPFHAVLRCGNLTSDVQVFPRPEPVIIDEEVDPMPKNVQTDLEIVGFIEIGDISSPPVLSRHLVLPIAVNKEGDEIGTGTTDDTEEDTSTNQMAGKSPNFCVLLHGSLKVEGMVALVQLGPDWYGMLYSQADSKKKSNLMMSLFDPGSEPLPWLGRMSQLGPASDAAENPYGEDDSKSPFPIQPKHKRSYAQNVTVWIKASGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFWELLKSMAELLERECTLLPDSAHPDAAFQLSHAAQQLKLASSIDSKYAAFEHNITPMLTDFSGGGGDRI", "length": 518 }, "evidence": [ { "id": "A0A4X1THU5", "url": "https://omabrowser.org/oma/group/A0A4X1THU5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5EA76-1", "protein_name": "Integrator complex subunit 14", "gene_name": "INTS14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATHNQRGESNRFPLPFPFPSKLYIMCMANLEELQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPEPFVIDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMVQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTGTSEYAGYDHNITPLQTDFSGSSAERI", "length": 518 }, "evidence": [ { "id": "A0A4X1THU5", "url": "https://omabrowser.org/oma/group/A0A4X1THU5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5ZK21-1", "protein_name": "Integrator complex subunit 14", "gene_name": "INTS14", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAVHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALLGVCNIVQQEWGAAIPCQVVLVTDGCLGIGRGSLRHSLATHNQRSESNRFPLPFPFPSKLYVMCMANLEELQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTSDVQVFPRPEPFIIDEEIDPIPKAINTDLEIVGFVDIADISSPPVLSRHLVLPIALNREGDEVGPGITDDTEDENSANQIAGKIPNFCVLLHGSLKVEGMVAVVQLGPEWYGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGDDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKVASTGASEYTAYDHNIAPLQTDFPTTSTERM", "length": 518 }, "evidence": [ { "id": "A0A4X1THU5", "url": "https://omabrowser.org/oma/group/A0A4X1THU5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q66H58-1", "protein_name": "Integrator complex subunit 14", "gene_name": "Ints14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATQNQRSESSRFPLPFPFPSKLYVMCMANLEELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAALKCGHLTADVQVFPRPEPFVIDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGAGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVALVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTEYAVYDLNITPLHTDFSGSSTERM", "length": 515 }, "evidence": [ { "id": "A0A4X1THU5", "url": "https://omabrowser.org/oma/group/A0A4X1THU5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R3P6-1", "protein_name": "Integrator complex subunit 14", "gene_name": "Ints14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATQNQRSESNRFPLPFPFPSKLYVMCMANLEELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPEPFVIDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGAGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVALVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTEYAIYDHNITPLHTDFSGSSTERM", "length": 515 }, "evidence": [ { "id": "A0A4X1THU5", "url": "https://omabrowser.org/oma/group/A0A4X1THU5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96SY0-1", "protein_name": "Integrator complex subunit 14", "gene_name": "INTS14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSIEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATQNQRSESNRFPLPFPFPSKLYIMCMANLEELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPEPFVVDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPETAHPDAAFQLTHAAQQLKLASTGTSEYAAYDQNITPLHTDFSGSSTERI", "length": 518 }, "evidence": [ { "id": "A0A4X1THU5", "url": "https://omabrowser.org/oma/group/A0A4X1THU5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VPY0-1", "protein_name": "Integrator complex subunit 14", "gene_name": "IntS14", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPTLIALDASLSMLRPVPGRNEHTYQSLATKGIQHLLDNLTAAGKLEHVALLSYSTTAELKVDFTRDYDQVRQAVKKVEPVDKACLMSMLKAVVSIMSPWGNQNILQVVVFTDCGLGFGNTSITGFLEAYAEKESEPEFGFLKTLANYNLNFICLGLHGDYYFTRGLAVYQQLLDKVSLKGQLFMTKPAKSSDAVEGNPNPNPNPSHKSELGRTTVFELIERLCEASYKSSEVTLKCGSYFRMEASVLLWPPTAPYEQKSHIFGREPTIRHTDQKIEVCGFLSLSDIGSPATLSRHWVLPKVEREKSGSSRRSGNLSAAAKPPKLNLDTSNPNYELEKLEADIKEFYAKDSKDTEESGDDDVTIVLKPGPQTEQQKENLCVLLHGALKMENMAALVRVGDKWYGFIYAFTDSKKKSNLMLNILPPGTNVIPWLGDLESLGFPEDLAPGETASFPVRADRRSYSQSSVVWIRQASLQSDVQKVLRHAKKMPDKTQHFYKELNRIRRAALALGFVELLEALAMLLEKECAHLSLNGASNDCTLQLQHAATELRKTSNRDMKSMIVPLQKVGASDAGSTAATAPAPAYMY", "length": 587 }, "evidence": [ { "id": "A0A4X1THU5", "url": "https://omabrowser.org/oma/group/A0A4X1THU5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THU5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THU5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THU5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THU5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THU5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THU5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1THU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5" }, { "id": "PF20504", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20504" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 14 C-terminal", "eco_id": "ECO_0000259", "start_pos": 404, "end_pos": 511, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1THU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5" }, { "id": "PF19435", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19435" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 14 beta-barrel", "eco_id": "ECO_0000259", "start_pos": 209, "end_pos": 356, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1THU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THU5" }, { "id": "PF13519", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13519" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 117, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 385, "end_pos": 387 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 502, "end_pos": 504 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TFR5-1", "uniprot_ac": "A0A4X1TFR5", "uniprot_id": "A0A4X1TFR5_PIG", "mass": { "chemical_mass": 24217.0, "monoisotopic_mass": 24217.0 }, "refseq": {}, "gene_names": [ { "name": "RPS13", "type": "recommended", "evidence": [ { "id": "A0A4X1TFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein uS15", "type": "recommended", "evidence": [ { "id": "A0A4X1TFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S13", "type": "synonym", "evidence": [ { "id": "A0A4X1TFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FAD3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAD3#function" }, { "database": "UniProtKB", "id": "ARBA00045441", "url": "https://www.uniprot.org/uniprotkb/ARBA00045441#function" }, { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPS13", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5", "locus": { "chromosome": "2", "start_pos": 42033378, "end_pos": 42030248, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013381", "url": "https://www.ensembl.org/id/ENSSSCG00000013381" } ] } } ], "crossref": [ { "id": "A0A4X1TFR5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TFR5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00353", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00353", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "3J7R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=3J7R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR000589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11885", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11885", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11885:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11885:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00003j7r", "url": "https://www.rcsb.org/structure/pdb_00003j7r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "3J7R", "url": "https://www.rcsb.org/structure/3J7R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00312", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00312", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TFR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAD3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTERVVHVEMHFGLCSHADARNHIEQLLLPQARTCEVTSCVHGGFLRRSHLLSLFRCLTAAIMGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA", "length": 213, "header": "tr|A0A4X1TFR5-1|A0A4X1TFR5_PIG Isoform 1 of Small ribosomal subunit protein uS15 OS=Sus scrofa OX=9823 GN=RPS13 PE=1 SV=1 CANONICAL=A0A4X1TFR5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TFR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5/entry#A0A4X1TFR5-1", "sequence": { "sequence": "MTERVVHVEMHFGLCSHADARNHIEQLLLPQARTCEVTSCVHGGFLRRSHLLSLFRCLTAAIMGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA", "length": 213, "header": "tr|A0A4X1TFR5-1|A0A4X1TFR5_PIG Isoform 1 of Small ribosomal subunit protein uS15 OS=Sus scrofa OX=9823 GN=RPS13 PE=1 SV=1 CANONICAL=A0A4X1TFR5-1" }, "locus": { "chromosome": "2", "start_pos": 42033333, "end_pos": 42030447, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014615.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014615.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014220.4", "url": "https://www.ensembl.org/id/ENSSSCP00000014220.4" } ] } }, { "isoform_ac": "A0A8W4FAD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5/entry#A0A8W4FAD3-1", "sequence": { "sequence": "MTERVVHVEMHFGLCSHADARNHIEQLLLPQARTCEVTSCVHGGFLRRSHLLSLFRCLTAAIMGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWK", "length": 202, "header": "tr|A0A8W4FAD3-1|A0A4X1TFR5_PIG Computationally mapped isoform of Small ribosomal subunit protein uS15 OS=Sus scrofa OX=9823 GN=RPS13 PE=1 SV=1 CANONICAL=A0A4X1TFR5-1" }, "locus": { "chromosome": "2", "start_pos": 42032697, "end_pos": 42030447, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097798.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097798.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076237.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076237.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Structure of the mammalian ribosome-Sec61 complex to 3.4 A resolution.", "journal": "Cell", "date": "2014", "authors": "Voorhees Rebecca M, Fern\u00e1ndez Israel S, Scheres Sjors H W, Hegde Ramanujan S", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "reference": [ { "type": "PubMed", "id": "24930395", "url": "https://glygen.org/publication/PubMed/24930395" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-SSC-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "pmid": "" }, { "name": "negative regulation of RNA splicing", "id": "GO:0033119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033119", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA 5'-UTR binding", "id": "GO:0048027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048027", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "pmid": "" }, { "name": "small ribosomal subunit rRNA binding", "id": "GO:0070181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070181", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TFR5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFR5" }, { "id": "SM01386", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01386" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small ribosomal subunit protein uS15 N-terminal", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 122, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TG88-1", "uniprot_ac": "A0A4X1TG88", "uniprot_id": "A0A4X1TG88_PIG", "mass": { "chemical_mass": 8294.0, "monoisotopic_mass": 8294.0 }, "refseq": { "ac": "XP_001926173", "name": "protein kish-B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926173" }, "gene_names": [ { "name": "TMEM167B", "type": "recommended", "evidence": [ { "id": "A0A4X1TG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG88" } ] }, { "name": "TMEM167B", "type": "synonym", "evidence": [ { "id": "XP_001926173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926173" } ] } ], "protein_names": [ { "name": "Protein kish", "type": "recommended", "evidence": [ { "id": "A0A4X1TG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG88/entry#names_and_taxonomy" } ] }, { "name": "protein kish-B", "type": "synonym", "evidence": [ { "id": "XP_001926173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926173" } ] } ], "function": [ { "annotation": "Involved in the early part of the secretory pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TG88", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG88#function" }, { "database": "UniProtKB", "id": "ARBA00002154", "url": "https://www.uniprot.org/uniprotkb/ARBA00002154#function" }, { "database": "UniProtKB", "id": "RU910717", "url": "https://www.uniprot.org/uniprotkb/RU910717#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TG88", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG88" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMEM167B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG88", "locus": { "chromosome": "4", "start_pos": 110965939, "end_pos": 110971481, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037816", "url": "https://www.ensembl.org/id/ENSSSCG00000037816" } ] } } ], "crossref": [ { "id": "A0A4X1TG88", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TG88", "database": "AlphaFoldDB", "categories": [] }, { "id": "100151851", "url": "https://www.ncbi.nlm.nih.gov/gene/100151851", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100151851", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151851", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVMAFYI", "url": "https://omabrowser.org/oma/group/IVMAFYI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TG88", "url": "https://www.orthodb.org/?gene=A0A4X1TG88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46815", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46815", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46815:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46815:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06842", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06842", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001926173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926173", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TG88", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TG88-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG88-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNVYSLDGILVFGLLFVCTCAYFKKVPRLKTWLLSEKKGVWGVFYKAAVIGTRLHAAVAIACVVMAFYVLFIK", "length": 74, "header": "tr|A0A4X1TG88-1|A0A4X1TG88_PIG Isoform 1 of Protein kish OS=Sus scrofa OX=9823 GN=TMEM167B PE=3 SV=1 CANONICAL=A0A4X1TG88-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TG88-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG88/entry#A0A4X1TG88-1", "sequence": { "sequence": "MTNVYSLDGILVFGLLFVCTCAYFKKVPRLKTWLLSEKKGVWGVFYKAAVIGTRLHAAVAIACVVMAFYVLFIK", "length": 74, "header": "tr|A0A4X1TG88-1|A0A4X1TG88_PIG Isoform 1 of Protein kish OS=Sus scrofa OX=9823 GN=TMEM167B PE=3 SV=1 CANONICAL=A0A4X1TG88-1" }, "locus": { "chromosome": "4", "start_pos": 110971385, "end_pos": 110968341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050321.2", "url": "https://www.ensembl.org/id/ENSSSCT00000050321.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052035.1", "url": "https://www.ensembl.org/id/ENSSSCP00000052035.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TG88", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG88" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100151851", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151851", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7F5X2-1", "protein_name": "Protein kish-B", "gene_name": "Tmem167b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNVYSLDGILVFGLLFVCTCAYFKKVPRLKTWLLSEKKGVWGVFYKGKVLSGHREEMEISGQCGATNCCDWDPTACCCCNCLHCNGLLRPVYQMNSKVSHSSTANQGDKDEELVGSLDPV", "length": 121 }, "evidence": [ { "id": "A0A4X1TG88", "url": "https://omabrowser.org/oma/group/A0A4X1TG88/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZSX4-1", "protein_name": "Protein kish", "gene_name": "Tmem167b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNVYSLDGILVFGLLFVCTCAYFKKVPRLKTWLLSEKKGVWGVFYKAAVIGTRLHAAVAIACIVMAFYVLFIK", "length": 74 }, "evidence": [ { "id": "A0A4X1TG88", "url": "https://omabrowser.org/oma/group/A0A4X1TG88/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0IIL4-1", "protein_name": "Protein kish-B", "gene_name": "TMEM167B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTNVYSLDGILVFGLLFVCTCAYFKKVPRLKTWLLSEKKGVWGVFYKAAVIGTRLHAAVAIACIVMAFYVLFIK", "length": 74 }, "evidence": [ { "id": "A0A4X1TG88", "url": "https://omabrowser.org/oma/group/A0A4X1TG88/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AZW1-1", "protein_name": "Protein kish-B", "gene_name": "tmem167b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTNVYSFDGILVFGLLFICTCAYLKKVPRLNSWLLSEKKGVWGVFYKAAVIGTRLHVVVAASCLCMAFYLIFLK", "length": 74 }, "evidence": [ { "id": "A0A4X1TG88", "url": "https://omabrowser.org/oma/group/A0A4X1TG88/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80X45-1", "protein_name": "Protein kish-B", "gene_name": "Tmem167b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTNVYSLDGILVFGLLFVCTCAYFKKVPRLKTWLLSEKKGVWGVFYKAAVIGTRLHAAVAIACIVMAFYVLFIK", "length": 74 }, "evidence": [ { "id": "A0A4X1TG88", "url": "https://omabrowser.org/oma/group/A0A4X1TG88/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRX6-1", "protein_name": "Protein kish-B", "gene_name": "TMEM167B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTNVYSLDGILVFGLLFVCTCAYFKKVPRLKTWLLSEKKGVWGVFYKAAVIGTRLHAAVAIACVVMAFYVLFIK", "length": 74 }, "evidence": [ { "id": "A0A4X1TG88", "url": "https://omabrowser.org/oma/group/A0A4X1TG88/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "constitutive secretory pathway", "id": "GO:0045054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045054", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TG88", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG88" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TG88", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TG97-1", "uniprot_ac": "A0A4X1TG97", "uniprot_id": "A0A4X1TG97_PIG", "mass": { "chemical_mass": 10156.0, "monoisotopic_mass": 10156.0 }, "refseq": { "ac": "XP_005664554", "name": "cytochrome c oxidase subunit 6B1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664554" }, "gene_names": [ { "name": "COX6B", "type": "recommended", "evidence": [ { "id": "A0A4X1TG97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG97" } ] }, { "name": "COX6B", "type": "synonym", "evidence": [ { "id": "XP_005664554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664554" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase subunit", "type": "recommended", "evidence": [ { "id": "A0A4X1TG97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG97/entry#names_and_taxonomy" } ] }, { "name": "cytochrome c oxidase subunit 6B1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005664554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664554" } ] } ], "function": [ { "annotation": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TG97", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG97#function" }, { "database": "UniProtKB", "id": "PIRNR000278", "url": "https://www.uniprot.org/uniprotkb/PIRNR000278#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TG97", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG97" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "COX6B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG97", "locus": {} } ], "crossref": [ { "id": "A0A4X1TG97", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TG97", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002907", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002907", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00926", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00926", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100038022", "url": "https://www.ncbi.nlm.nih.gov/gene/100038022", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8ZO8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZO8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZOU", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZOU&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZP8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZP8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSO", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSO&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CE2", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CE2&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR003213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NEWIAKW", "url": "https://omabrowser.org/oma/group/NEWIAKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TG97", "url": "https://www.orthodb.org/?gene=A0A4X1TG97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11387", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11387", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008zo8", "url": "https://www.rcsb.org/structure/pdb_00008zo8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zou", "url": "https://www.rcsb.org/structure/pdb_00008zou", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zp8", "url": "https://www.rcsb.org/structure/pdb_00008zp8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsn", "url": "https://www.rcsb.org/structure/pdb_00008zsn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zso", "url": "https://www.rcsb.org/structure/pdb_00008zso", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsq", "url": "https://www.rcsb.org/structure/pdb_00008zsq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009ce2", "url": "https://www.rcsb.org/structure/pdb_00009ce2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZO8", "url": "https://www.rcsb.org/structure/8ZO8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZOU", "url": "https://www.rcsb.org/structure/8ZOU", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZP8", "url": "https://www.rcsb.org/structure/8ZP8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSN", "url": "https://www.rcsb.org/structure/8ZSN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSO", "url": "https://www.rcsb.org/structure/8ZSO", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSQ", "url": "https://www.rcsb.org/structure/8ZSQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CE2", "url": "https://www.rcsb.org/structure/9CE2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF02297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9707564", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9707564", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9864848", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9864848", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005664554", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664554", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TG97", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TG97-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RLH7", "url": "https://www.uniprot.org/uniprotkb/F1RLH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RLH7-1", "url": "https://www.uniprot.org/uniprotkb/F1RLH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEDIQTKIKNYQTAPFDSRFPNQNQTRNCWQNYLDFHRCEKAMTAKGGDVSVCEWYRRVYKSLCPISWVSAWDDRRAEGTFPGKI", "length": 86, "header": "tr|A0A4X1TG97-1|A0A4X1TG97_PIG Isoform 1 of Cytochrome c oxidase subunit OS=Sus scrofa OX=9823 GN=COX6B PE=1 SV=1 CANONICAL=A0A4X1TG97-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TG97-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG97/entry#A0A4X1TG97-1", "sequence": { "sequence": "MAEDIQTKIKNYQTAPFDSRFPNQNQTRNCWQNYLDFHRCEKAMTAKGGDVSVCEWYRRVYKSLCPISWVSAWDDRRAEGTFPGKI", "length": 86, "header": "tr|A0A4X1TG97-1|A0A4X1TG97_PIG Isoform 1 of Cytochrome c oxidase subunit OS=Sus scrofa OX=9823 GN=COX6B PE=1 SV=1 CANONICAL=A0A4X1TG97-1" }, "locus": { "chromosome": "6", "start_pos": 45102533, "end_pos": 45093724, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060808.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060808.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039905.1", "url": "https://www.ensembl.org/id/ENSSSCP00000039905.1" } ] } }, { "isoform_ac": "F1RLH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG97/entry#F1RLH7-1", "sequence": { "sequence": "MAEDIQTKIKNYQTAPFDSRFPNQNQTRNCWQNYLDFHRCEKAMTAKGGDVSVCEWYRRVYKSLCPISWLSGIPSFFSSDKHH", "length": 83, "header": "tr|F1RLH7-1|A0A4X1TG97_PIG Computationally mapped isoform of Cytochrome c oxidase subunit OS=Sus scrofa OX=9823 GN=COX6B PE=1 SV=3 CANONICAL=A0A4X1TG97-1" }, "locus": { "chromosome": "6", "start_pos": 45102166, "end_pos": 45093724, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003212.3", "url": "https://www.ensembl.org/id/ENSSSCT00000003212.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003131.3", "url": "https://www.ensembl.org/id/ENSSSCP00000003131.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RLH7", "url": "https://www.uniprot.org/uniprotkb/F1RLH7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-SSC-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-SSC-9707564", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9707564", "resource": "Reactome", "description": "Cytoprotection by HMOX1" }, { "id": "R-SSC-9864848", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9864848", "resource": "Reactome", "description": "Complex IV assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "P14854-1", "protein_name": "Cytochrome c oxidase subunit 6B1", "gene_name": "COX6B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEDMETKIKNYKTAPFDSRFPNQNQTRNCWQNYLDFHRCQKAMTAKGGDISVCEWYQRVYQSLCPTSWVTDWDEQRAEGTFPGKI", "length": 86 }, "evidence": [ { "id": "A0A4X1TG97", "url": "https://omabrowser.org/oma/group/A0A4X1TG97/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P56391-1", "protein_name": "Cytochrome c oxidase subunit 6B1", "gene_name": "Cox6b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEDIKTKIKNYKTAPFDSRFPNQNQTKNCWQNYLDFHRCEKAMTAKGGDVSVCEWYRRVYKSLCPVSWVSAWDDRIAEGTFPGKI", "length": 86 }, "evidence": [ { "id": "A0A4X1TG97", "url": "https://omabrowser.org/oma/group/A0A4X1TG97/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q01519-1", "protein_name": "Cytochrome c oxidase subunit 12, mitochondrial", "gene_name": "COX12", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MADQENSPLHTVGFDARFPQQNQTKHCWQSYVDYHKCVNMKGEDFAPCKVFWKTYNALCPLDWIEKWDDQREKGIFAGDINSD", "length": 83 }, "evidence": [ { "id": "A0A4X1TG97", "url": "https://omabrowser.org/oma/group/A0A4X1TG97/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54P95-1", "protein_name": "Probable cytochrome c oxidase subunit 6B", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEGEQLQTAPYNPRFPQQNQTKHCWANYVDYYGCVKHYNGDNSKCQTFFNSMNSLCPAAWISEWDEQKAADLFPSDRV", "length": 78 }, "evidence": [ { "id": "A0A4X1TG97", "url": "https://omabrowser.org/oma/group/A0A4X1TG97/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TG97", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG97" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TG97", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG97" } ], "pmid": "" }, { "name": "respiratory chain complex IV", "id": "GO:0045277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045277", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TG97", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TG97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 25, "end_pos": 27 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TGN8-1", "uniprot_ac": "A0A4X1TGN8", "uniprot_id": "A0A4X1TGN8_PIG", "mass": { "chemical_mass": 25516.0, "monoisotopic_mass": 25516.0 }, "refseq": { "ac": "XP_003128841", "name": "glutathione S-transferase A4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128841" }, "gene_names": [ { "name": "LOC100510917", "type": "recommended", "evidence": [ { "id": "A0A4X1TGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8" } ] }, { "name": "LOC100510917", "type": "synonym", "evidence": [ { "id": "XP_003128841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128841" } ] } ], "protein_names": [ { "name": "Glutathione S-transferase", "type": "recommended", "evidence": [ { "id": "A0A4X1TGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.18", "type": "synonym", "evidence": [ { "id": "A0A4X1TGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8/entry#names_and_taxonomy" } ] }, { "name": "glutathione S-transferase A4", "type": "synonym", "evidence": [ { "id": "XP_003128841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128841" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGN8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100510917", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8", "locus": {} } ], "crossref": [ { "id": "A0A4X1TGN8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TGN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03208", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03208", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100510917", "url": "https://www.ncbi.nlm.nih.gov/gene/100510917", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100510917", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100510917", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LDLMMMI", "url": "https://omabrowser.org/oma/group/LDLMMMI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TGN8", "url": "https://www.orthodb.org/?gene=A0A4X1TGN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571:SF101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571:SF101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00043", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00043", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003128841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128841", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16437", "url": "https://www.rhea-db.org/rhea/16437", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TGN8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TGN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAKPKLYYFRGRGRMESIRWLLAAAGVEFEEEFFETREQYEKLKKDGLLLFGQVPLVEIDGMALTQTRAILSYLAAKYNLHGKDLKERVRIDMYADGTLDLMMMVALAAFKPPGEKEENLALVVEKAKTRYFPVFEKILKDQGEDFLVGNKFSWADIQLLEAILMMEELDASVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDSHYVKVVRNVLQF", "length": 222, "header": "tr|A0A4X1TGN8-1|A0A4X1TGN8_PIG Isoform 1 of Glutathione S-transferase OS=Sus scrofa OX=9823 GN=LOC100510917 PE=1 SV=1 CANONICAL=A0A4X1TGN8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TGN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8/entry#A0A4X1TGN8-1", "sequence": { "sequence": "MAAKPKLYYFRGRGRMESIRWLLAAAGVEFEEEFFETREQYEKLKKDGLLLFGQVPLVEIDGMALTQTRAILSYLAAKYNLHGKDLKERVRIDMYADGTLDLMMMVALAAFKPPGEKEENLALVVEKAKTRYFPVFEKILKDQGEDFLVGNKFSWADIQLLEAILMMEELDASVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDSHYVKVVRNVLQF", "length": 222, "header": "tr|A0A4X1TGN8-1|A0A4X1TGN8_PIG Isoform 1 of Glutathione S-transferase OS=Sus scrofa OX=9823 GN=LOC100510917 PE=1 SV=1 CANONICAL=A0A4X1TGN8-1" }, "locus": { "chromosome": "7", "start_pos": 46621389, "end_pos": 46610645, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024099.2", "url": "https://www.ensembl.org/id/ENSSSCT00000024099.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021438.2", "url": "https://www.ensembl.org/id/ENSSSCP00000021438.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGN8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100510917", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100510917", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NQS2-1", "protein_name": "glutathione transferase", "gene_name": "LOC396380", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAKPVLYYFNGRGKMESIRWLLAAAGVEFEEVFLETREQYEKLLQSGILMFQQVPMVEIDGMKLVQTRAILNYIAGKYNLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDKVKQCAFVVEKATSRYFPAYEKVLKDHGQDFLVGNRLSWADIHLLEAILMLEEKKSDALSGFPLLQAFKKRISSIPTIKKFLAPGSKRKPISDDKYVETVRRVLRMYYDVKPH", "length": 229 }, "evidence": [ { "id": "A0A4X1TGN8", "url": "https://omabrowser.org/oma/group/A0A4X1TGN8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3I5H1-1", "protein_name": "Glutathione S-transferase", "gene_name": "LOC100753254", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "METKPKLYYFHGRGRMESIRWLLAAAGVEFEEEFLETREQYEKLQKDGRLLFDQVPLVEIDGMPLTQSRAILSYLAAKYNLYGKDLKERLRIDMYADGTLDLMLMIAQAPFKPPKEKEESYALVVKRAKTRYFPVFEKILKDHGEDFLVGNQLSWADIQLLEAILMVEELSAPVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDAHYVEVVRNVLNF", "length": 222 }, "evidence": [ { "id": "A0A4X1TGN8", "url": "https://omabrowser.org/oma/group/A0A4X1TGN8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P24472-1", "protein_name": "Glutathione S-transferase A4", "gene_name": "Gsta4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAKPKLYYFNGRGRMESIRWLLAAAGVEFEEEFLETREQYEKMQKDGHLLFGQVPLVEIDGMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKEESYDLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELSAPVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDGPYVEVVRTVLKF", "length": 222 }, "evidence": [ { "id": "A0A4X1TGN8", "url": "https://omabrowser.org/oma/group/A0A4X1TGN8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGN8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGN8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGN8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGN8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16437", "name": "", "equation": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16437", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16437" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8" }, { "id": "PS50405", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50405" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST C-terminal", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 208, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGN8" }, { "id": "PS50404", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50404" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST N-terminal", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 83, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TGP3-1", "uniprot_ac": "A0A4X1TGP3", "uniprot_id": "A0A4X1TGP3_PIG", "mass": { "chemical_mass": 48624.0, "monoisotopic_mass": 48624.0 }, "refseq": { "ac": "XP_020954488", "name": "chorion-specific transcription factor GCMa isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954488" }, "gene_names": [ { "name": "GCM1", "type": "recommended", "evidence": [ { "id": "A0A4X1TGP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ] }, { "name": "GCM1", "type": "synonym", "evidence": [ { "id": "XP_020954488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954488" } ] } ], "protein_names": [ { "name": "Glial cells missing transcription factor 1", "type": "synonym", "evidence": [ { "id": "A0A4X1TGP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3/entry#names_and_taxonomy" } ] }, { "name": "chorion-specific transcription factor GCMa isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020954488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954488" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GCM1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3", "locus": { "chromosome": "7", "start_pos": 46767498, "end_pos": 46791037, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000032538", "url": "https://www.ensembl.org/id/ENSSSCG00000032538" } ] } } ], "crossref": [ { "id": "A0A4X1TGP3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TGP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "414910", "url": "https://www.ncbi.nlm.nih.gov/gene/414910", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12414", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12414", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12414:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12414:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020954488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954488", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TGP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPENAGSEDKEVLSWDINDMKLPQNVKKTDWFQEWPDAYEKHIYSSEDRSAQRHLSSWAMRNTNNHNSRILKKSCLGVVVCGRDCLAPEGRKVYLRPAICDKARQKQQRKRCPNCDGPLKLIPCRGHGGFPVTNFWRHDGRFIFFQSKGEHDHPKPETKLEAEARRAVKKTHLAASSSKLKQGPEIKPLPGETPSWESLTRSFQEGIQLPSSYSGHLIGNTPQQKALNDCSSFSESYGLGGTTDPADPTPPLGAPQLYEKCSLSDGQISSNRDLLQLPVSGVFGYSDPQTWNDNMALERNPLNDNSCPNYPFALTSWPYDFSPPQNASEPFPQQIPMEPPAAKTSCPPLWPNQGGDLYEEKVPVDFNGYYPSTTCRSPQEEPFLLTYTSQPCHQYSLPGKSSKWNLDEEMRYLGLDHCNNEMLLNLCSLR", "length": 431, "header": "tr|A0A4X1TGP3-1|A0A4X1TGP3_PIG Isoform 1 of Glial cells missing transcription factor 1 OS=Sus scrofa OX=9823 GN=GCM1 PE=4 SV=1 CANONICAL=A0A4X1TGP3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TGP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3/entry#A0A4X1TGP3-1", "sequence": { "sequence": "MEPENAGSEDKEVLSWDINDMKLPQNVKKTDWFQEWPDAYEKHIYSSEDRSAQRHLSSWAMRNTNNHNSRILKKSCLGVVVCGRDCLAPEGRKVYLRPAICDKARQKQQRKRCPNCDGPLKLIPCRGHGGFPVTNFWRHDGRFIFFQSKGEHDHPKPETKLEAEARRAVKKTHLAASSSKLKQGPEIKPLPGETPSWESLTRSFQEGIQLPSSYSGHLIGNTPQQKALNDCSSFSESYGLGGTTDPADPTPPLGAPQLYEKCSLSDGQISSNRDLLQLPVSGVFGYSDPQTWNDNMALERNPLNDNSCPNYPFALTSWPYDFSPPQNASEPFPQQIPMEPPAAKTSCPPLWPNQGGDLYEEKVPVDFNGYYPSTTCRSPQEEPFLLTYTSQPCHQYSLPGKSSKWNLDEEMRYLGLDHCNNEMLLNLCSLR", "length": 431, "header": "tr|A0A4X1TGP3-1|A0A4X1TGP3_PIG Isoform 1 of Glial cells missing transcription factor 1 OS=Sus scrofa OX=9823 GN=GCM1 PE=4 SV=1 CANONICAL=A0A4X1TGP3-1" }, "locus": { "chromosome": "7", "start_pos": 46787793, "end_pos": 46767795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042648.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042648.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035468.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035468.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell differentiation involved in embryonic placenta development", "id": "GO:0060706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060706", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "pmid": "" }, { "name": "gliogenesis", "id": "GO:0042063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042063", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "pmid": "" }, { "name": "regulation of cell differentiation involved in embryonic placenta development", "id": "GO:0060800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060800", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TGP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP3" }, { "id": "PS50807", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50807" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GCM", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 169, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 250 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 327, "end_pos": 329 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TGP4-1", "uniprot_ac": "A0A4X1TGP4", "uniprot_id": "A0A4X1TGP4_PIG", "mass": { "chemical_mass": 27042.0, "monoisotopic_mass": 27042.0 }, "refseq": { "ac": "NP_001230989", "name": "POU domain class 2-associating factor 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230989" }, "gene_names": [ { "name": "POU2AF1", "type": "recommended", "evidence": [ { "id": "A0A4X1TGP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" } ] }, { "name": "POU2AF1", "type": "synonym", "evidence": [ { "id": "NP_001230989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230989" } ] } ], "protein_names": [ { "name": "POU class 2 associating factor 1", "type": "synonym", "evidence": [ { "id": "NP_001230989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230989" } ] }, { "name": "POU class 2 homeobox associating factor 1", "type": "synonym", "evidence": [ { "id": "A0A4X1TGP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4/entry#names_and_taxonomy" } ] }, { "name": "POU domain class 2-associating factor 1", "type": "synonym", "evidence": [ { "id": "NP_001230989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230989" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "POU2AF1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4", "locus": { "chromosome": "9", "start_pos": 39119052, "end_pos": 39144606, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015016", "url": "https://www.ensembl.org/id/ENSSSCG00000015016" } ] } } ], "crossref": [ { "id": "A0A4X1TGP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TGP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100512063", "url": "https://www.ncbi.nlm.nih.gov/gene/100512063", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015389", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015389", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512063", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512063", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SPIGQPC", "url": "https://omabrowser.org/oma/group/SPIGQPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TGP4", "url": "https://www.orthodb.org/?gene=A0A4X1TGP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15363:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15363:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09310", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09310", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001230989", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230989", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TGP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TGP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLWQKPAAPEQAPAPPRPYQGVRVKEPVKELLRRKRGHASSGAPVAPTAVVLPHQPLATYTTVGPSCLDMEVSASTVTEEGALCTGWLSQPAPAALQPLAPWTPYTEYVSHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASQPLITNVTTRSAATPTVGPQLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDVEDPRRTISSLLLEEEDSDTYSLNHTLSVEGF", "length": 251, "header": "tr|A0A4X1TGP4-1|A0A4X1TGP4_PIG Isoform 1 of POU class 2 homeobox associating factor 1 OS=Sus scrofa OX=9823 GN=POU2AF1 PE=4 SV=1 CANONICAL=A0A4X1TGP4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TGP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4/entry#A0A4X1TGP4-1", "sequence": { "sequence": "MLWQKPAAPEQAPAPPRPYQGVRVKEPVKELLRRKRGHASSGAPVAPTAVVLPHQPLATYTTVGPSCLDMEVSASTVTEEGALCTGWLSQPAPAALQPLAPWTPYTEYVSHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASQPLITNVTTRSAATPTVGPQLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDVEDPRRTISSLLLEEEDSDTYSLNHTLSVEGF", "length": 251, "header": "tr|A0A4X1TGP4-1|A0A4X1TGP4_PIG Isoform 1 of POU class 2 homeobox associating factor 1 OS=Sus scrofa OX=9823 GN=POU2AF1 PE=4 SV=1 CANONICAL=A0A4X1TGP4-1" }, "locus": { "chromosome": "9", "start_pos": 39144508, "end_pos": 39121616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016380.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016380.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015940.3", "url": "https://www.ensembl.org/id/ENSSSCP00000015940.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 48, "start_aa": "Thr", "end_pos": 48, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr48", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512063", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512063", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9PC97-1", "protein_name": "POU domain class 2-associating factor 1 isoform X1", "gene_name": "pou2af1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKLVSEAPTSKPYQGVRVKDPVKELLRRKRGNAARSTATVMVPSNTLQSCTLAGTSTFAEVPQSGLNDSVVDVSGLCTGWIAQTTSTTALQPLSHWTPPDCQHHDPAIPSHADMYVQPICPGYTVVGSSPMLTFAHAPLFTNLATVSTSSSVLPQVEVPDSSLTYIPWAQPLSTIPGPVMQASSALSAPQLFPVPLTLPVLSPEPEPPQVEPQQAPEGTLALEKLLEDNEVHKESYICNSSLFAEDI", "length": 248 }, "evidence": [ { "id": "A0A4X1TGP4", "url": "https://omabrowser.org/oma/group/A0A4X1TGP4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q16633-1", "protein_name": "POU domain class 2-associating factor 1", "gene_name": "POU2AF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLWQKPTAPEQAPAPARPYQGVRVKEPVKELLRRKRGHASSGAAPAPTAVVLPHQPLATYTTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPATLQPLAPWTPYTEYVPHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTRSSATPAVGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDMEDPRRAASSLTIDKLLLEEEDSDAYALNHTLSVEGF", "length": 256 }, "evidence": [ { "id": "A0A4X1TGP4", "url": "https://omabrowser.org/oma/group/A0A4X1TGP4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2KJA4-1", "protein_name": "POU domain class 2-associating factor 1", "gene_name": "POU2AF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLWQKPTAPEQAPAPPRPYQGVRVKEPVKELLRRKRGHASSGASVTPTAVVLPHQPLATYTTVGPSCLDMEVSASTVTEEGALCAGWLSQPAPAALQPLAPWTPYTEYVSHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASQPLITNVTTRSAAAPTVGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLPDAEDPRRAIGSLTIDKLLLEEEDSDTYALNHTLSVEGF", "length": 256 }, "evidence": [ { "id": "A0A4X1TGP4", "url": "https://omabrowser.org/oma/group/A0A4X1TGP4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q64693-1", "protein_name": "POU domain class 2-associating factor 1", "gene_name": "Pou2af1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWQKSTAPEQAPAPPRPYQGVRVKEPVKELLRRKRGHTSVGAAGPPTAVVLPHQPLATYSTVGPSCLDMEVSASTVTEEGTLCAGWLSQPAPATLQPLAPWTPYTEYVSHEAVSCPYSTDMYVQPVCPSYTVVGPSSVLTYASPPLITNVTPRSTATPAVGPQLEGPEHQAPLTYFPWPQPLSTLPTSSLQYQPPAPTLSGPQFVQLPISIPEPVLQDMDDPRRAISSLTIDKLLLEEEESNTYELNHTLSVEGF", "length": 256 }, "evidence": [ { "id": "A0A4X1TGP4", "url": "https://omabrowser.org/oma/group/A0A4X1TGP4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" } ], "pmid": "" }, { "name": "POU domain binding", "id": "GO:0070974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070974", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" } ], "pmid": "" }, { "name": "germinal center B cell differentiation", "id": "GO:0002314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002314", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TGP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TGP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TGP4" }, { "id": "PS52003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OCA", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 38, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 48 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 243, "end_pos": 245 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TH87-1", "uniprot_ac": "A0A4X1TH87", "uniprot_id": "A0A4X1TH87_PIG", "mass": { "chemical_mass": 121048.0, "monoisotopic_mass": 121048.0 }, "refseq": { "ac": "XP_020941046", "name": "SMC5-SMC6 complex localization factor protein 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941046" }, "gene_names": [ { "name": "SLF1", "type": "recommended", "evidence": [ { "id": "A0A4X1TH87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ] }, { "name": "SLF1", "type": "synonym", "evidence": [ { "id": "XP_020941046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941046" } ] } ], "protein_names": [ { "name": "SMC5-SMC6 complex localization factor protein 1", "type": "recommended", "evidence": [ { "id": "A0A4X1TH87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87/entry#names_and_taxonomy" } ] }, { "name": "Ankyrin repeat domain-containing protein 32", "type": "synonym", "evidence": [ { "id": "A0A4X1TH87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87/entry#names_and_taxonomy" } ] }, { "name": "BRCT domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A4X1TH87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87/entry#names_and_taxonomy" } ] }, { "name": "SMC5-SMC6 complex localization factor protein 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_020941046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941046" } ] } ], "function": [ { "annotation": "Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance. The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks. Promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87#function" }, { "database": "UniProtKB", "id": "ARBA00059100", "url": "https://www.uniprot.org/uniprotkb/ARBA00059100#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLF1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87", "locus": { "chromosome": "2", "start_pos": 101375607, "end_pos": 101313091, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014163", "url": "https://www.ensembl.org/id/ENSSSCG00000014163" } ] } } ], "crossref": [ { "id": "A0A4X1TH87", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TH87", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17750", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17750", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522125", "url": "https://www.ncbi.nlm.nih.gov/gene/100522125", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YIGHYLF", "url": "https://omabrowser.org/oma/group/YIGHYLF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46677:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46677:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020941046", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941046", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TH87-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDGAPKHIIQMTGFKMEEKEALGKLLLKLDCTFIKSEKYKNCTHLIAERLCKSEKFLAACAAGKWVLTKDYIIHSAKSGRWLDETTYEWGYKIEKDSHYSPQMQSAPKRWREELKRTGAPGAFHRWKVVLLVRTDKRSDSLVRVLEAGKANVILPKNSPSGITHVIASNARIKAEQGKDNFKAPFYPIQYLGDFLLEKEIQNDEDSQTSSVWNNHNNQEKKKDFRKDMGFLEMKGALKETMCRAQKETKNHDEDVNISSLLTEHHRREKFKNSSKSLKFVKMRNALGRHTYGNQKETKKKDEDIQRYTLRKKRKKEKERDPRKDIEHNRSTSRKHIYRDQKEMKNSVFADQTKESKTKDIRTDVNIVEVKNALRKHIYRAQAIRYSCIRIDKQPVYNVEVKNAEFPRGVLNLIESLIEGQFFKEAIEELSSLQAHYIPPVCLLHALLENILQDNIDTFSGRYFDILSALLHLHPPWKSPAMSRYYLELFQCPACMKGAWSLIEVLIRSCLFNERFCHQISENIIGSKVLHLTLLKFFFNLVESEVRHLSQKLYDWSDSQSLKITGKAILLEIFWSGSETSGLLTKPVNMLLEWTIYSHKEKCKSNDVFKHELAYLLTGILGAAIDYWIFLGLKMGRNVMRHMSDDLGSYVSLSCDDFSSQELEVFICSFSSSWLQMFVAEAVFKKLCFQSSISISSEPLSLQKMVYSYLPALGKTGVRGTGKMQIPKKIGQRPCFESQRALIMLNGAKQKQVEGPPELPELNLAKCSSSLKRLKKKSEGELSCSKENCPSLVTKINFHKTNLKGETALHRACINNQVEKLILLLSMPGIDINVKDNAGWTPLHEACNYGNTVCVQEILQRCPEVDLLTQVDGVTPLHDALSNGHVEIGKLLLQHGGPVLLQQRNSKGELPLDYVSSQIKEELFAITKIEDTVENFHAQAEKHFYHQQLEFGSFLLSRMLLNFCSIFDLSSEFFLAFKGLTHLNELLMACQNYKETPSAHTDWLLDLYARNTKTLQKLPNILKELPENLKTCPGVHTEALLVTLEMMCRSVTEFS", "length": 1055, "header": "tr|A0A4X1TH87-1|A0A4X1TH87_PIG Isoform 1 of SMC5-SMC6 complex localization factor protein 1 OS=Sus scrofa OX=9823 GN=SLF1 PE=4 SV=1 CANONICAL=A0A4X1TH87-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TH87-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87/entry#A0A4X1TH87-1", "sequence": { "sequence": "MEDGAPKHIIQMTGFKMEEKEALGKLLLKLDCTFIKSEKYKNCTHLIAERLCKSEKFLAACAAGKWVLTKDYIIHSAKSGRWLDETTYEWGYKIEKDSHYSPQMQSAPKRWREELKRTGAPGAFHRWKVVLLVRTDKRSDSLVRVLEAGKANVILPKNSPSGITHVIASNARIKAEQGKDNFKAPFYPIQYLGDFLLEKEIQNDEDSQTSSVWNNHNNQEKKKDFRKDMGFLEMKGALKETMCRAQKETKNHDEDVNISSLLTEHHRREKFKNSSKSLKFVKMRNALGRHTYGNQKETKKKDEDIQRYTLRKKRKKEKERDPRKDIEHNRSTSRKHIYRDQKEMKNSVFADQTKESKTKDIRTDVNIVEVKNALRKHIYRAQAIRYSCIRIDKQPVYNVEVKNAEFPRGVLNLIESLIEGQFFKEAIEELSSLQAHYIPPVCLLHALLENILQDNIDTFSGRYFDILSALLHLHPPWKSPAMSRYYLELFQCPACMKGAWSLIEVLIRSCLFNERFCHQISENIIGSKVLHLTLLKFFFNLVESEVRHLSQKLYDWSDSQSLKITGKAILLEIFWSGSETSGLLTKPVNMLLEWTIYSHKEKCKSNDVFKHELAYLLTGILGAAIDYWIFLGLKMGRNVMRHMSDDLGSYVSLSCDDFSSQELEVFICSFSSSWLQMFVAEAVFKKLCFQSSISISSEPLSLQKMVYSYLPALGKTGVRGTGKMQIPKKIGQRPCFESQRALIMLNGAKQKQVEGPPELPELNLAKCSSSLKRLKKKSEGELSCSKENCPSLVTKINFHKTNLKGETALHRACINNQVEKLILLLSMPGIDINVKDNAGWTPLHEACNYGNTVCVQEILQRCPEVDLLTQVDGVTPLHDALSNGHVEIGKLLLQHGGPVLLQQRNSKGELPLDYVSSQIKEELFAITKIEDTVENFHAQAEKHFYHQQLEFGSFLLSRMLLNFCSIFDLSSEFFLAFKGLTHLNELLMACQNYKETPSAHTDWLLDLYARNTKTLQKLPNILKELPENLKTCPGVHTEALLVTLEMMCRSVTEFS", "length": 1055, "header": "tr|A0A4X1TH87-1|A0A4X1TH87_PIG Isoform 1 of SMC5-SMC6 complex localization factor protein 1 OS=Sus scrofa OX=9823 GN=SLF1 PE=4 SV=1 CANONICAL=A0A4X1TH87-1" }, "locus": { "chromosome": "2", "start_pos": 101375120, "end_pos": 101314180, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015472.4", "url": "https://www.ensembl.org/id/ENSSSCT00000015472.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015062.3", "url": "https://www.ensembl.org/id/ENSSSCP00000015062.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A6QR20-1", "protein_name": "SMC5-SMC6 complex localization factor protein 1", "gene_name": "SLF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEDDAPKHIIQMTGFKVEEKEALGKLLLKLDCTFIKSEKYKNCTHLIAERLCKSEKFLAACAAGKWVLTKDYIIHSAQSGRWLDETTYEWGYKIEKDSHYSPQMQSAPKRWREELKRTGAPGAFHKWKVVLLVRADKRSDSLVRVLEAGKANVILPKNSPTGITHVIASNARIKAEQEKDDFKAPFYPIQYLEDFLLEKEIHNDEDSQTNSTWKNHSSQEKSNDFRENMGFLEMKGTLKETMCRTQKEMKNHDEDVTISSILTEHQSKERFRDSRKNLKFVKMRNALGRHTYRNQEMKKKDEDIQSIYTLRKKRKKEKERDSRKDIEHDRSTLRKHIYRDQKERKNSVFAGHAKESKTKDIRTNVDIVDLKNALRKHIYRAQAVRYRGIRIDKQPAYNVEVKNAEFPRGILNLIESLIEGQFFKEAIEELSSLQAHYIPPVYLLHALLENILQDNIDTFSGRYFHILSALLHLHPPWKSPAMSTYYLELFQCPTCMKGTWSLIEVLIRSCLFNESFCHQISENIIGSKVLHLTLLKFFFNLIESEVRHLSQKLYDWSDSQSLKITGKAVLLEIFWSGNETSGLLTKPVNMLLEWTIYSHKEKCKSNDVFRHELAYLLTGILGAAIDYWIVLGLNMGRNVMRHMSDDVGSYVSLSCDDFSSQDLEIFISSFSSSWLQMFVAEAVFKKLCLQNSISISSEPLSLQKMVYSYLPALGKTGVRGTRKMQKPKKIGLRPCFESQRALIMLNGAKQKQGEGLPEIPELNLAKCSSSLKRLKKKSEGELSCSKENCPSLVTKINFHKTNLKGETALHRACINNQVDRLILLLSMPGIDINVKDNAGWTPLHEACNYGNTVCVQEILQRCPEVDLLTQVDGVTPLHDALSNGHVEIGKLLLQHGGPVLLQQRNSKGELPLDYVVSSQIKEELFAITKIEDTVENFHAQAEKHFYHQQLEFGSFLLSRMLLNFCSIFGLSSESLAFKGLTHLSELLIACQNYKETTSVHTDWLLDLYARNIMTLQKLPNALKELPENVKVCPGVHTEALLVTLEVMCRSVTEIS", "length": 1055 }, "evidence": [ { "id": "A0A4X1TH87", "url": "https://omabrowser.org/oma/group/A0A4X1TH87/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R3P9-1", "protein_name": "SMC5-SMC6 complex localization factor protein 1", "gene_name": "Slf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSATKHIIQMTGFKMEEKEALVKLLLKLDCTFIKSEKYKNCTHLIAERLCKSEKFLAACAAGKWVLTKDYIIHSAKSGRWLDETTYEWGYKIEKDSHYSPQMQSAPKRWREELKRTGAPGAFHRWKVVLLVRADKRSDSLVRVLEAGKANVILPKNSPSGITHVIASNARISAEREQENFKAPFYPIQYLGDFLLEKEIQNDEHSQISPAWTKYNNQEKGNDVGFPEMKGAGENMYRTQNKMENHNKNVSDRFVLSEHHKKKFKDFRKDIRSVKKRNTLRRHGLENQKETKKKDKNIQRSYILRKKNKKEGYCKTDDAHDTIRSMLKKRGHYREQKEMKNPLLTDGTKESKTKDVKTNMNLIEIKNALKKQIYKDIYRAQAVRYNCIRVDKQPVYNVEVKNSEFPRGILNLIENLIEGQFFKEAIEELSSLQAHYIPPVCLLHAILENVLQDKIDTFSGRYFHILSALLHLHPPWKSPAMLKYYLELFQCPTCMKGAWDFTEVLIRSCLFNEDFCHQISENISTKVVNLTLLKFFFNLLEGEVRHLSQKLCDWSDSQSLKVTEKAILHEIFWSGSETSGLLTKPVNMLLEWTIYSHKEKCKSNDVFKHELSYLLTGILGAAVDYWIFLGIQMGRNVIRHMSDDLGSYISLSCDDFSSKELEIFICSFSSSWLQMFVAEAIFKKLCLQGPTSTCTEPLSLQKIIDSYLPILGKMDIHGAGKMQSPKKLCQRPCLESQRALLMLNGAKRKQAEGRPELLELNRAKCSSSLKKLKKKSEELSCSKENCPSLVTKMNFHKTNLKGETALHRVCIKNQVEKLIILLSLPGIDINVKDNAGWTPLHEACNYGNTECVQEILQRCPEVDLLTQVDGVTPLHDALSNGHVEIGKLLLQRGGPELLQQRNSKGELPLDYVLSPKDKEELFAITNIDDTVDNFHAKTQKHFYHQQLEFGSFLLSRMLINFCSIFDLSSEFILAFKGLGHLNELLMACNSDTEASNAHTDWLLDVYARNIKTLKKLPSVLKELPENLNVCPGVHTEALLVTLKMMCQSITELS", "length": 1054 }, "evidence": [ { "id": "A0A4X1TH87", "url": "https://omabrowser.org/oma/group/A0A4X1TH87/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BQI6-1", "protein_name": "SMC5-SMC6 complex localization factor protein 1", "gene_name": "SLF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDGTPKHIIQMTGFKMEEKEALVKLLLKLDCTFIKSEKYKNCTHLIAERLCKSEKFLAACAAGKWILTKDYIIHSAKSGRWLDETTYEWGYKIEKDSRYSPQMQSAPKRWREELKRTGAPGAFHRWKVVLLVRTDKRSDSLIRVLEAGKANVILPKSSPSGITHVIASNARIKAEKEKDNFKAPFYPIQYLGDFLLEKEIQNDEDSQTNSVWTEHSNEETNKDFRKDAGFLEMKGALRETMYRTQKEMQNHEDVNVGSILIQHHKKEKFSGSSKDLKFVKMRNTFGSHTYENQKEIKKKDEDIQRSYTLRRKRKKGKESNCKKGVEHEKIKSTLRRHIYNRDQKEMKNSIFAEYAKESKAMAIKTDVDVVEIKNTLRKHIYRAQAVRYNCIRIDKQPVYNVEVKNAEFPRGVLNLIESLIEGHFFKEAIEELSTLQAHYIPPVCVLHALLENVLQDNIDTFSGRYFHILSALLHLHPPWKSPAMSRYYLELFQCPTCMKGAWSLVEVLIRSCLFNESFCHQISENIGSKVLHLTLLKFFFNLIESEVQHLSQKLYDWSDSQNLKITGKAMLLEIFWSGSETSGLLTKPVNMLLEWTIYSHKEKFKSNDVFKHELAYLLAGILGAAIDYWIFLGLKMGRNVMRHMSDDLGSYVSLSCDDFSSQELEIFICSFSSSWLQMFVAEAVFKKLCLQSSGSVSSEPLSLQKMVYSYLPALGKTGVLGSGKIQVSKKIGQRPCFDSQRTLLMLNGTKQKQVEGLPELLDLNLAKCSSSLKKLKKKSEGELSCSKENCPSVVKKMNFHKTNLKGETALHRACINNQVEKLILLLSLPGIDINVKDNAGWTPLHEACNYGNTVCVQEILQRCPEVDLLTQVDGVTPLHDALSNGHVEIGKLLLQHGGPVLLQQRNAKGELPLDYVVSPQIKEELFAITKIEDTVENFHAQAEKHFHYQQLEFGSFLLSRMLLNFCSIFDLSSEFILASKGLTHLNELLMACKSHKETTSVHTDWLLDLYAGNIKTLQKLPHILKELPENLKVCPGVHTEALMITLEMMCRSVMEFS", "length": 1058 }, "evidence": [ { "id": "A0A4X1TH87", "url": "https://omabrowser.org/oma/group/A0A4X1TH87/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein localization to site of double-strand break", "id": "GO:1990166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990166", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" }, { "name": "positive regulation of protein-containing complex assembly", "id": "GO:0031334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031334", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair", "id": "GO:2000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000781", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" }, { "name": "positive regulation of maintenance of mitotic sister chromatid cohesion", "id": "GO:0034184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034184", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" }, { "name": "nuclear inclusion body", "id": "GO:0042405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042405", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TH87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TH87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TH87" }, { "id": "SM00292", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00292" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BRCT", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 80, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 42, "end_pos": 44 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1THK7-1", "uniprot_ac": "A0A4X1THK7", "uniprot_id": "A0A4X1THK7_PIG", "mass": { "chemical_mass": 16120.0, "monoisotopic_mass": 16120.0 }, "refseq": { "ac": "XP_020926779", "name": "lysozyme-like protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926779" }, "gene_names": [ { "name": "LYZL4", "type": "recommended", "evidence": [ { "id": "A0A4X1THK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7" } ] }, { "name": "LYZL4", "type": "synonym", "evidence": [ { "id": "XP_020926779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926779" } ] } ], "protein_names": [ { "name": "Lysozyme like 4", "type": "synonym", "evidence": [ { "id": "A0A4X1THK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7/entry#names_and_taxonomy" } ] }, { "name": "lysozyme-like protein 4", "type": "synonym", "evidence": [ { "id": "XP_020926779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926779" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THK7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LYZL4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7", "locus": { "chromosome": "13", "start_pos": 25987314, "end_pos": 25995089, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011279", "url": "https://www.ensembl.org/id/ENSSSCG00000011279" } ] } } ], "crossref": [ { "id": "A0A4X1THK7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1THK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522642", "url": "https://www.ncbi.nlm.nih.gov/gene/100522642", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522642", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522642", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AWPSWSL", "url": "https://omabrowser.org/oma/group/AWPSWSL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1THK7", "url": "https://www.orthodb.org/?gene=A0A4X1THK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11407", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11407", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11407:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11407:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00062", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00062", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020926779", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926779", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1THK7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1THK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKASVVLSLIGYLVVPSGAAVLGRCVVAKKLHEGGLSDYEGYSLENWVCLAYFESKFNPTAVYDNLRGDYTGYGLFQIRNHDWCDHGKNRCHVSCSALLNPNLKETIKCAKKIVQGKRGMGAWPSWTLNCQNSDTLARWLDGCKL", "length": 145, "header": "tr|A0A4X1THK7-1|A0A4X1THK7_PIG Isoform 1 of Lysozyme like 4 OS=Sus scrofa OX=9823 GN=LYZL4 PE=3 SV=1 CANONICAL=A0A4X1THK7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1THK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7/entry#A0A4X1THK7-1", "sequence": { "sequence": "MKASVVLSLIGYLVVPSGAAVLGRCVVAKKLHEGGLSDYEGYSLENWVCLAYFESKFNPTAVYDNLRGDYTGYGLFQIRNHDWCDHGKNRCHVSCSALLNPNLKETIKCAKKIVQGKRGMGAWPSWTLNCQNSDTLARWLDGCKL", "length": 145, "header": "tr|A0A4X1THK7-1|A0A4X1THK7_PIG Isoform 1 of Lysozyme like 4 OS=Sus scrofa OX=9823 GN=LYZL4 PE=3 SV=1 CANONICAL=A0A4X1THK7-1" }, "locus": { "chromosome": "13", "start_pos": 25992518, "end_pos": 25988138, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012348.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012348.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012025.3", "url": "https://www.ensembl.org/id/ENSSSCP00000012025.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THK7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522642", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522642", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G0I7-1", "protein_name": "Lysozyme-like protein 4", "gene_name": "Lyzl4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQVHLVLPLISCLLTPIGASILGRCVVAKRLQEGGLDYFEGYSLENWVCLAYFESKFNPSAMYENSQGGYTGFGLFQIRDSEWCDHGRNLCSASCSALLNPNLKDTIKCAKKIVKGKKGMGAWPVWSRYCQLSDTLERWLDGCGLTRRGRPDALASHVL", "length": 159 }, "evidence": [ { "id": "A0A4X1THK7", "url": "https://omabrowser.org/oma/group/A0A4X1THK7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2T9N7-1", "protein_name": "Lysozyme-like protein 4", "gene_name": "LYZL4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKASVVLSLIGYLVVPSDTAVLGRCVVAKKLHEGGLSDFEGYSLENWVCLAYFESKFNPMAVYENSRSDFIGYGLFQIRNHDWCDHGRNRCHMSCSALLNPDLKKTIECAKTIVKGKRGMGAWPSWTLNCQHSDTLARWLDGCKL", "length": 145 }, "evidence": [ { "id": "A0A4X1THK7", "url": "https://omabrowser.org/oma/group/A0A4X1THK7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96KX0-1", "protein_name": "Lysozyme-like protein 4", "gene_name": "LYZL4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKASVVLSLLGYLVVPSGAYILGRCTVAKKLHDGGLDYFEGYSLENWVCLAYFESKFNPMAIYENTREGYTGFGLFQMRGSDWCGDHGRNRCHMSCSALLNPNLEKTIKCAKTIVKGKEGMGAWPTWSRYCQYSDTLARWLDGCKL", "length": 146 }, "evidence": [ { "id": "A0A4X1THK7", "url": "https://omabrowser.org/oma/group/A0A4X1THK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D925-1", "protein_name": "Lysozyme-like protein 4", "gene_name": "Lyzl4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQLYLVLLLISYLLTPIGASILGRCTVAKMLYDGGLNYFEGYSLENWVCLAYFESKFNPSAVYEDPQDGSTGFGLFQIRDNEWCGHGKNLCSVSCTALLNPNLKDTIQCAKKIVKGKHGMGAWPIWSKNCQLSDVLDRWLDGCDL", "length": 145 }, "evidence": [ { "id": "A0A4X1THK7", "url": "https://omabrowser.org/oma/group/A0A4X1THK7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THK7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THK7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THK7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fusion of sperm to egg plasma membrane involved in single fertilization", "id": "GO:0007342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007342", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THK7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lysozyme activity", "id": "GO:0003796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003796", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THK7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1THK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THK7" }, { "id": "PS00128", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00128" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl hydrolases family 22 (GH22)", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 109, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1THN6-1", "uniprot_ac": "A0A4X1THN6", "uniprot_id": "A0A4X1THN6_PIG", "mass": { "chemical_mass": 84749.0, "monoisotopic_mass": 84749.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A4X1THN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6", "locus": {} } ], "crossref": [ { "id": "A0A4X1THN6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1THN6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1THN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1THN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYLGMDTSLAEGQVTLRVALWLLGFWAVLAPVQCSQGHPSWRYISSEVVIPRKELHHGKGFQMPGWLSYSLHFGGQRHIIHMRHKKLFWSRHLLTMTQDDQGALQMDYPFIPSDCYYFGYLEEIPLSMVTVDTCSGGLEGIMKLDDLAYEIKPLKYSERFEHVVSQIVADANATGPAYRLGHKEDKYPLFPEADISIAPRGGGRLFAGPRGYMRGFGQFSNSMYRVFNNVTSCVEILVRISSLSDSMYEGIYLRFFLIAVLIYNVRDPTAMNNYNVRNGAYANYHKRHLRPVIRPTTSFMIIKDGPRQGVFSPELYSICGEKDLLFIGQLGRHYFLLSIVVTYTSARSLGLYYDNENCICMRRATCLMSQYPALTDAFSECSFVHLRNILVANHCVFIGVERYFNASMTNMRCGNYIVEDWETCDCGSYKQCYSNLCCQHDCVFEPGAICNEELCCTNCTYSVPGTLCRPIQNICDLPEYCKGNNYSCPDNFYLQDGTPCTEEAYCYKGNCTDRTLHCKEIFGINSVNANDACYTINTRGDRFGHCIQLRNTLTHRACNSEDIKCGRLQCSNITHVPSLQDRVSFHQSKISEYWCWGVDRIYSPETTDVGHVRNGTPCAPGRFCENNFCNGTISALIYDCLPEKCHFRGICNNQRNCHCHVGWEPPLCLQRGSGGSINSGPSSGRIRSVQKSTREIFYLRVVFGRLYAFIAALLFGVATNVKNIKTSWSFRPPLGNLSFSKPKMGSGQ", "length": 748, "header": "tr|A0A4X1THN6-1|A0A4X1THN6_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A4X1THN6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1THN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6/entry#A0A4X1THN6-1", "sequence": { "sequence": "MYLGMDTSLAEGQVTLRVALWLLGFWAVLAPVQCSQGHPSWRYISSEVVIPRKELHHGKGFQMPGWLSYSLHFGGQRHIIHMRHKKLFWSRHLLTMTQDDQGALQMDYPFIPSDCYYFGYLEEIPLSMVTVDTCSGGLEGIMKLDDLAYEIKPLKYSERFEHVVSQIVADANATGPAYRLGHKEDKYPLFPEADISIAPRGGGRLFAGPRGYMRGFGQFSNSMYRVFNNVTSCVEILVRISSLSDSMYEGIYLRFFLIAVLIYNVRDPTAMNNYNVRNGAYANYHKRHLRPVIRPTTSFMIIKDGPRQGVFSPELYSICGEKDLLFIGQLGRHYFLLSIVVTYTSARSLGLYYDNENCICMRRATCLMSQYPALTDAFSECSFVHLRNILVANHCVFIGVERYFNASMTNMRCGNYIVEDWETCDCGSYKQCYSNLCCQHDCVFEPGAICNEELCCTNCTYSVPGTLCRPIQNICDLPEYCKGNNYSCPDNFYLQDGTPCTEEAYCYKGNCTDRTLHCKEIFGINSVNANDACYTINTRGDRFGHCIQLRNTLTHRACNSEDIKCGRLQCSNITHVPSLQDRVSFHQSKISEYWCWGVDRIYSPETTDVGHVRNGTPCAPGRFCENNFCNGTISALIYDCLPEKCHFRGICNNQRNCHCHVGWEPPLCLQRGSGGSINSGPSSGRIRSVQKSTREIFYLRVVFGRLYAFIAALLFGVATNVKNIKTSWSFRPPLGNLSFSKPKMGSGQ", "length": 748, "header": "tr|A0A4X1THN6-1|A0A4X1THN6_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A4X1THN6-1" }, "locus": { "chromosome": "AEMK02000566.1", "start_pos": 289305, "end_pos": 286621, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041236.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041236.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056752.3", "url": "https://www.ensembl.org/id/ENSSSCP00000056752.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6" } ], "pmid": "" }, { "name": "sperm head plasma membrane", "id": "GO:1990913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990913", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1THN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 614, "end_pos": 616, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1THN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6" }, { "id": "PS50214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Disintegrin", "eco_id": "ECO_0000259", "start_pos": 410, "end_pos": 496, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1THN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 636, "end_pos": 669, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1THN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1THN6" }, { "id": "PS50215", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50215" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M12B", "eco_id": "ECO_0000259", "start_pos": 211, "end_pos": 390, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 458, "end_pos": 460 }, { "start_pos": 485, "end_pos": 487 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 614, "end_pos": 616 }, { "start_pos": 630, "end_pos": 632 }, { "start_pos": 736, "end_pos": 738 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TI56-1", "uniprot_ac": "A0A4X1TI56", "uniprot_id": "A0A4X1TI56_PIG", "mass": { "chemical_mass": 62445.0, "monoisotopic_mass": 62445.0 }, "refseq": {}, "gene_names": [ { "name": "BBOF1", "type": "recommended", "evidence": [ { "id": "A0A4X1TI56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TI56" } ] } ], "protein_names": [ { "name": "Basal body-orientation factor 1", "type": "recommended", "evidence": [ { "id": "A0A4X1TI56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TI56/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 176", "type": "synonym", "evidence": [ { "id": "A0A4X1TI56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TI56/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TI56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TI56" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BBOF1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TI56", "locus": { "chromosome": "7", "start_pos": 97368049, "end_pos": 97316711, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002356", "url": "https://www.ensembl.org/id/ENSSSCG00000002356" } ] } } ], "crossref": [ { "id": "A0A4X1TI56", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TI56", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002356", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002356", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR032777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14845:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14845:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14988", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14988", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1TI56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TI56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TI56-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TI56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSKGKDKKKGQGKDKKKKKIIKVEESSVERAKANASLWEARLEVTELSRIEYRDTSRRLAKSNEDLKKQQYKMEKDTMSVLSYLKKQDQEKDNLIEKLKQQLNETKEKAQEEKEKLEQKYTVQINELEGQFHQKAKEIGMIQMELKTIKQFQKRKIQVEKELDDLKENLRNTERKHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAVMQLNNAGRTVFKENVYLQKALAYHLKETDTLQKNSQKLQETQTLLLQQKEINDLLVKEKIMQLTQQRSQIQTLQKKVVSLETALSCMTKEFETEVLKLQQQAMVENQAGQIEIFKLQQLLQMKDREMNRMKKLAKNILDERTEVESFFLDALHQVKQQILTSRKRYKQIAQAAFNFKMREACARRTEYPKIRTFDGREHSTNSVNQDLMEADKWTDVHGNVDIGDLTWEQKEKVLRLLFAKMNGFVPRKYSQSSRPPVPDYVVLDEGKAKEFGDEIKLPDQTFITQQVPILDSSGELVISNIQNESQESDMRTY", "length": 529, "header": "tr|A0A4X1TI56-1|A0A4X1TI56_PIG Isoform 1 of Basal body-orientation factor 1 OS=Sus scrofa OX=9823 GN=BBOF1 PE=3 SV=1 CANONICAL=A0A4X1TI56-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TI56-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TI56/entry#A0A4X1TI56-1", "sequence": { "sequence": "MPSKGKDKKKGQGKDKKKKKIIKVEESSVERAKANASLWEARLEVTELSRIEYRDTSRRLAKSNEDLKKQQYKMEKDTMSVLSYLKKQDQEKDNLIEKLKQQLNETKEKAQEEKEKLEQKYTVQINELEGQFHQKAKEIGMIQMELKTIKQFQKRKIQVEKELDDLKENLRNTERKHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAVMQLNNAGRTVFKENVYLQKALAYHLKETDTLQKNSQKLQETQTLLLQQKEINDLLVKEKIMQLTQQRSQIQTLQKKVVSLETALSCMTKEFETEVLKLQQQAMVENQAGQIEIFKLQQLLQMKDREMNRMKKLAKNILDERTEVESFFLDALHQVKQQILTSRKRYKQIAQAAFNFKMREACARRTEYPKIRTFDGREHSTNSVNQDLMEADKWTDVHGNVDIGDLTWEQKEKVLRLLFAKMNGFVPRKYSQSSRPPVPDYVVLDEGKAKEFGDEIKLPDQTFITQQVPILDSSGELVISNIQNESQESDMRTY", "length": 529, "header": "tr|A0A4X1TI56-1|A0A4X1TI56_PIG Isoform 1 of Basal body-orientation factor 1 OS=Sus scrofa OX=9823 GN=BBOF1 PE=3 SV=1 CANONICAL=A0A4X1TI56-1" }, "locus": { "chromosome": "7", "start_pos": 97367390, "end_pos": 97316768, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082203.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082203.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064677.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064677.2" } ] } }, { "isoform_ac": "A0A5G2QZL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TI56/entry#A0A5G2QZL6-1", "sequence": { "sequence": "MPSKGKDKKKGQGKDKKKKKIIKVEESSVERAKANASLWEARLEVTELSRIEYRDTSRRLAKSNEDLKKQQYKMEKDTMSVLSYLKKQDQEKDNLIEKLKQQLNETKEKAQEEKEKLEQKYTVQINELEGQFHQKAKEIGMIQMELKTIKQFQKRKIQVEKELDDLKENLRNTERKHQETLRRLESRFFEEKVHICLNEKYFVY", "length": 204, "header": "tr|A0A5G2QZL6-1|A0A4X1TI56_PIG Computationally mapped isoform of Basal body-orientation factor 1 OS=Sus scrofa OX=9823 GN=BBOF1 PE=3 SV=2 CANONICAL=A0A4X1TI56-1" }, "locus": { "chromosome": "7", "start_pos": 97344386, "end_pos": 97316768, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074758.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074758.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063685.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063685.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZL6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TI56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TI56" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TI56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TI56" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TI56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TI56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 35, "end_pos": 37 }, { "start_pos": 519, "end_pos": 521 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TII7-1", "uniprot_ac": "A0A4X1TII7", "uniprot_id": "A0A4X1TII7_PIG", "mass": { "chemical_mass": 33483.0, "monoisotopic_mass": 33483.0 }, "refseq": {}, "gene_names": [ { "name": "MEOX2", "type": "recommended", "evidence": [ { "id": "A0A4X1TII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" } ] } ], "protein_names": [ { "name": "Mesenchyme homeobox 2", "type": "synonym", "evidence": [ { "id": "A0A4X1TII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TII7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MEOX2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7", "locus": { "chromosome": "9", "start_pos": 84943199, "end_pos": 85010157, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015357", "url": "https://www.ensembl.org/id/ENSSSCG00000015357" } ] } } ], "crossref": [ { "id": "A0A4X1TII7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TII7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QHHASWH", "url": "https://omabrowser.org/oma/group/QHHASWH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24328:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24328:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1TII7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TII7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHPLFGCLRSPHATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEEGMFASQHHRGHHHHHHHHHHHHQQQQHQALQTNWHLPQMSSPPSAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGSSTPTGAACPPGDYGRQALSPAEAEKRSGGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAATLQQTGDSLANEDSHDSDHSSEHAHL", "length": 303, "header": "tr|A0A4X1TII7-1|A0A4X1TII7_PIG Isoform 1 of Mesenchyme homeobox 2 OS=Sus scrofa OX=9823 GN=MEOX2 PE=4 SV=1 CANONICAL=A0A4X1TII7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TII7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7/entry#A0A4X1TII7-1", "sequence": { "sequence": "MEHPLFGCLRSPHATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEEGMFASQHHRGHHHHHHHHHHHHQQQQHQALQTNWHLPQMSSPPSAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGSSTPTGAACPPGDYGRQALSPAEAEKRSGGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAATLQQTGDSLANEDSHDSDHSSEHAHL", "length": 303, "header": "tr|A0A4X1TII7-1|A0A4X1TII7_PIG Isoform 1 of Mesenchyme homeobox 2 OS=Sus scrofa OX=9823 GN=MEOX2 PE=4 SV=1 CANONICAL=A0A4X1TII7-1" }, "locus": { "chromosome": "9", "start_pos": 85009936, "end_pos": 84945181, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016732.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016732.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016286.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016286.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TII7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E7FEH1-1", "protein_name": "Homeobox protein MOX-2", "gene_name": "meox2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDHTLFGCLRSPHAPPQAVHPAFALHGRPEHLSSYPDLSSSSPPSTCIVSGYPGEDGGLFGGHQRGLSVSQQQHHHHHHHHHLAQQGGWHLPQSSSASPSAAGVRLGLGISGPDSGSSDVGPGGPSLCASTPSLGAGVPSGASCVPGGDFGRHTMSPAEAEKRNSKRRSDSSESQDGNYKSDVSSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAVAREKELVNVKKGTLLPSEFSGIAGLHTPDSLLNNEDSQDSDQSSEHAHL", "length": 302 }, "evidence": [ { "id": "A0A4X1TII7", "url": "https://omabrowser.org/oma/group/A0A4X1TII7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HN92-1", "protein_name": "Homeobox protein MOX-2", "gene_name": "Meox2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEHPLFGCLRSPHATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEESMFASQHHRGHHHHHHHHHHHHQQQQHQALQSNWHLPQMSSPPSAARHSLCLQPDSGGPPELGNSPPVLCSNSSSLGSSTPTGAACAPGDYGRQALSPADVEKRSGSKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAATLQQAGDSLANDDSRDSDHSSEHAHL", "length": 303 }, "evidence": [ { "id": "A0A4X1TII7", "url": "https://omabrowser.org/oma/group/A0A4X1TII7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P32443-1", "protein_name": "Homeobox protein MOX-2", "gene_name": "Meox2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEHPLFGCLRSPHATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEEGMFASQHHRGHHHHHHHHHHHHQQQQHQALQSNWHLPQMSSPPSAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGSSTPTGAACAPGDYGRQALSPADVEKRSGSKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAATLQQTGDSLANEDSRDSDHSSEHAHL", "length": 303 }, "evidence": [ { "id": "A0A4X1TII7", "url": "https://omabrowser.org/oma/group/A0A4X1TII7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P39020-1", "protein_name": "Homeobox protein MOX-2", "gene_name": "Meox2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHPLFGCLRSPHATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEEGMFASQHHRGHHHHHHHHHHHHQQQQHQALQSNWHLPQMSSPPSAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGSSTPTGAACAPRDYGRQALSPAEVEKRSGSKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAATLQQTGDSLANDDSRDSDHSSEHAHL", "length": 303 }, "evidence": [ { "id": "A0A4X1TII7", "url": "https://omabrowser.org/oma/group/A0A4X1TII7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P50222-1", "protein_name": "Homeobox protein MOX-2", "gene_name": "MEOX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEHPLFGCLRSPHATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEEGMFASQHHRGHHHHHHHHHHHHHQQQQHQALQTNWHLPQMSSPPSAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGSSTPTGAACAPGDYGRQALSPAEAEKRSGGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAATLQQTGDSIANEDSHDSDHSSEHAHL", "length": 304 }, "evidence": [ { "id": "A0A4X1TII7", "url": "https://omabrowser.org/oma/group/A0A4X1TII7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of cell migration involved in sprouting angiogenesis", "id": "GO:0090051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090051", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TII7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TII7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TII7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" } ], "pmid": "" }, { "name": "somite development", "id": "GO:0061053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061053", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TII7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TII7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TII7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TII7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TII7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TII7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TII7" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 184, "end_pos": 244, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TIL9-1", "uniprot_ac": "A0A4X1TIL9", "uniprot_id": "A0A4X1TIL9_PIG", "mass": { "chemical_mass": 35197.0, "monoisotopic_mass": 35197.0 }, "refseq": { "ac": "XP_020955668", "name": "olfactory receptor 4K14-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955668" }, "gene_names": [ { "name": "LOC100156174", "type": "synonym", "evidence": [ { "id": "XP_020955668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955668" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TIL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIL9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4K14-like", "type": "synonym", "evidence": [ { "id": "XP_020955668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955668" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIL9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIL9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIL9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIL9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIL9", "locus": {} } ], "crossref": [ { "id": "A0A4X1TIL9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TIL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156174", "url": "https://www.ncbi.nlm.nih.gov/gene/100156174", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156174", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156174", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGNIVIM", "url": "https://omabrowser.org/oma/group/CGNIVIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TIL9", "url": "https://www.orthodb.org/?gene=A0A4X1TIL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020955668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955668", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TIL9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TIL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTGNLSVVSEFVLLGLCQSWAMQVLLLLIFFMLYLIIVSGNIAIMILIIIDTHLHSPMYFLLANLSFVDMWLSSVTTPKMITDLVRENKTISFGGCMCQILFVHFVGGGEMVLLVVMAYDRYVAICKPLHYSTIMNLQKCLGLVVISWTIGFVHAMSQMAVIMQLPFCGPREMDSFFCDIPLVIKLACMDSHSLGMLMNADSGVLAMTCFILLLISYTYILFTVRQGSKTSASRALSTCTAHITVVVLFFGPCIFIYVWPLSITWVDKFLAVFYSVITPLLNPAIYTLRNKEIKNAMKRFRSYYLHAKENI", "length": 312, "header": "tr|A0A4X1TIL9-1|A0A4X1TIL9_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1TIL9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TIL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIL9/entry#A0A4X1TIL9-1", "sequence": { "sequence": "MDTGNLSVVSEFVLLGLCQSWAMQVLLLLIFFMLYLIIVSGNIAIMILIIIDTHLHSPMYFLLANLSFVDMWLSSVTTPKMITDLVRENKTISFGGCMCQILFVHFVGGGEMVLLVVMAYDRYVAICKPLHYSTIMNLQKCLGLVVISWTIGFVHAMSQMAVIMQLPFCGPREMDSFFCDIPLVIKLACMDSHSLGMLMNADSGVLAMTCFILLLISYTYILFTVRQGSKTSASRALSTCTAHITVVVLFFGPCIFIYVWPLSITWVDKFLAVFYSVITPLLNPAIYTLRNKEIKNAMKRFRSYYLHAKENI", "length": 312, "header": "tr|A0A4X1TIL9-1|A0A4X1TIL9_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1TIL9-1" }, "locus": { "chromosome": "7", "start_pos": 78864405, "end_pos": 78863470, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023615.3", "url": "https://www.ensembl.org/id/ENSSSCT00000023615.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025464.2", "url": "https://www.ensembl.org/id/ENSSSCP00000025464.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIL9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIL9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156174", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156174", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LDF2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100757926", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSKMDGGNQSVVSEFVILGLAHSQNLQVLLFVMFLLFYLLIVSGNIVIMVLITTDPHLHSPMYFLLANLSFVDMWLSSVTTPKMITDFLRKNKSISFSGCMSQIFFAHCIAAGEMVLLVVMAYDRYVAICKPLHYFTIMNLKRCTGLVLTSWTIGFVHAMSHLVVIVELPFCGPKKIDSFFCDMPLVIKLACMDSHDLDILMNADCGIVGVTCFILLLISYTYILITVRQSSKAGASKALSTCSAHITVVMIFFVPCIFIYVCPLNITWLDKFLAVFYSVFTPLLNPAIYTLRNKEMKNAMTRFINNYIDSKGNY", "length": 315 }, "evidence": [ { "id": "A0A4X1TIL9", "url": "https://omabrowser.org/oma/group/A0A4X1TIL9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6AIF3-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIMDGGNQSLVSEFVLLGLAHSQNIQALLFMMFLMLYLLIVSGNIVIMVLITFDPHLHSPMYFLLANLSFVDMWLSSVTTPKMITDFFRENKTISFAGCMCQVFFAHCIAAGEMVLLVVMAYDRYVAICKPLHYFTIMNLKRCTGLVLTSWTIGIVHALSHLVVIVELPFCSPKEIDSFFCDMPLVIKLACMDSHNLDILMYADCGVVGVTCFILLLISYTYILITVHQSSKAGASKALSTCTAHITVVMIFFVPCIFIYVWPLNITWLDKFLAVFYSVFTPLLNPAIYTLRNKEMKNAMKRFINTYRDFQGKS", "length": 315 }, "evidence": [ { "id": "A0A4X1TIL9", "url": "https://omabrowser.org/oma/group/A0A4X1TIL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3MY66-1", "protein_name": "Olfactory receptor", "gene_name": "OR4K55B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDAGNLSVVSEFVLLGLCHSWTMQVLLLLMFFMLYLIIVFGNIAIIILIITDPHLHSPMYFLLANLSFVDMWLCSVTTPKMITDFVRENKTISFGGCMCQILFVHFFGGGEMVLLVVMAYDRYVAICKPLHYSTIMNLQKCIGLVLTSWTTGFVHAMSQMAVIVQLPFCGPREIDSFFCDIPLVIKLACIDSYNLGILMNADSGVPAMTCFIVLLISYSYILLTIRQSSKAGTSRALSTCTAHITVVVLFFGPCIFIYVWPLSITWVDKFLAVFYSVITPLLNPAIYTLRNKEIKTAIKRFRSYYIHHKGNI", "length": 312 }, "evidence": [ { "id": "A0A4X1TIL9", "url": "https://omabrowser.org/oma/group/A0A4X1TIL9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIL9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIL9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIL9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIL9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIL9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TIY5-1", "uniprot_ac": "A0A4X1TIY5", "uniprot_id": "A0A4X1TIY5_PIG", "mass": { "chemical_mass": 88945.0, "monoisotopic_mass": 88945.0 }, "refseq": { "ac": "XP_003132667", "name": "zinc finger protein 148 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132667" }, "gene_names": [ { "name": "ZNF148", "type": "recommended", "evidence": [ { "id": "A0A4X1TIY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ] }, { "name": "ZNF148", "type": "synonym", "evidence": [ { "id": "XP_003132667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132667" } ] } ], "protein_names": [ { "name": "Zinc finger protein 148", "type": "recommended", "evidence": [ { "id": "A0A4X1TIY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 148 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003132667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132667" } ] } ], "function": [ { "annotation": "Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5#function" }, { "database": "UniProtKB", "id": "ARBA00060069", "url": "https://www.uniprot.org/uniprotkb/ARBA00060069#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF148", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5", "locus": { "chromosome": "13", "start_pos": 135089151, "end_pos": 134969729, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011858", "url": "https://www.ensembl.org/id/ENSSSCG00000011858" } ] } } ], "crossref": [ { "id": "100515279", "url": "https://www.ncbi.nlm.nih.gov/gene/100515279", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515279", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515279", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TIY5", "url": "https://www.orthodb.org/?gene=A0A4X1TIY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003132667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132667", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TIY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TKT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TKT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIDDKLEGLFLKCGGIDEMQSSRAMVVMGGVSGQSTVSGELQESVLQDRSMPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQMETHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQIREPADLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKSSGMDKESSLDKSDLKKDKNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVLKKINSKRSLKQPLEQNQTISPLSTYEESKVSKYAFELVDKQALLDSEGNADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAVASVIDESTTASILDSQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVPEVTQSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNQPAFSSIDKQVYAAMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHSFPFSGDETNHASATSTQDFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFPEFPLVNVNDNRAGMTSSPDATTGQTFG", "length": 794, "header": "tr|A0A4X1TIY5-1|A0A4X1TIY5_PIG Isoform 1 of Zinc finger protein 148 OS=Sus scrofa OX=9823 GN=ZNF148 PE=3 SV=1 CANONICAL=A0A4X1TIY5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TIY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5/entry#A0A4X1TIY5-1", "sequence": { "sequence": "MNIDDKLEGLFLKCGGIDEMQSSRAMVVMGGVSGQSTVSGELQESVLQDRSMPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQMETHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQIREPADLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKSSGMDKESSLDKSDLKKDKNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVLKKINSKRSLKQPLEQNQTISPLSTYEESKVSKYAFELVDKQALLDSEGNADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAVASVIDESTTASILDSQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVPEVTQSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNQPAFSSIDKQVYAAMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHSFPFSGDETNHASATSTQDFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFPEFPLVNVNDNRAGMTSSPDATTGQTFG", "length": 794, "header": "tr|A0A4X1TIY5-1|A0A4X1TIY5_PIG Isoform 1 of Zinc finger protein 148 OS=Sus scrofa OX=9823 GN=ZNF148 PE=3 SV=1 CANONICAL=A0A4X1TIY5-1" }, "locus": { "chromosome": "13", "start_pos": 135088887, "end_pos": 135019981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060773.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060773.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041156.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041156.1" } ] } }, { "isoform_ac": "A0A4X1TKT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5/entry#A0A4X1TKT3-1", "sequence": { "sequence": "TKGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGDETNHASATSTQDFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFPEFPLVNVNDNRAGMTSSPDATTGQTFG", "length": 144, "header": "tr|A0A4X1TKT3-1|A0A4X1TKT3_PIG Computationally mapped isoform of Zinc finger protein 148 OS=Sus scrofa OX=9823 GN=ZNF148 PE=3 SV=1 CANONICAL=A0A4X1TIY5-1" }, "locus": { "chromosome": "13", "start_pos": 135088887, "end_pos": 135007641, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012971.4", "url": "https://www.ensembl.org/id/ENSSSCT00000012971.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012630.3", "url": "https://www.ensembl.org/id/ENSSSCP00000012630.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515279", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515279", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIY5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 574, "end_pos": 576, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TIY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIY5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 171, "end_pos": 198, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 408, "end_pos": 410 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 574, "end_pos": 576 }, { "start_pos": 634, "end_pos": 636 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TIZ3-1", "uniprot_ac": "A0A4X1TIZ3", "uniprot_id": "A0A4X1TIZ3_PIG", "mass": { "chemical_mass": 37403.0, "monoisotopic_mass": 37403.0 }, "refseq": {}, "gene_names": [ { "name": "SDSL", "type": "recommended", "evidence": [ { "id": "A0A4X1TIZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3" } ] } ], "protein_names": [ { "name": "L-serine deaminase", "type": "recommended", "evidence": [ { "id": "A0A4X1TIZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3/entry#names_and_taxonomy" } ] }, { "name": "4.3.1.17", "type": "synonym", "evidence": [ { "id": "A0A4X1TIZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3/entry#names_and_taxonomy" } ] }, { "name": "4.3.1.19", "type": "synonym", "evidence": [ { "id": "A0A4X1TIZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3/entry#names_and_taxonomy" } ] }, { "name": "L-threonine dehydratase", "type": "synonym", "evidence": [ { "id": "A0A4X1TIZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SDSL", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3", "locus": { "chromosome": "14", "start_pos": 38471165, "end_pos": 38484155, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009870", "url": "https://www.ensembl.org/id/ENSSSCG00000009870" } ] } } ], "crossref": [ { "id": "A0A4X1TIZ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TIZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06448", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06448", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100154365", "url": "https://www.ncbi.nlm.nih.gov/gene/100154365", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154365", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154365", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DGWVNIH", "url": "https://omabrowser.org/oma/group/DGWVNIH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TLD0", "url": "https://www.orthodb.org/?gene=A0A4X1TLD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48078", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48078", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48078:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48078:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8849175", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8849175", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-977347", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-977347", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "19169", "url": "https://www.rhea-db.org/rhea/19169", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "22108", "url": "https://www.rhea-db.org/rhea/22108", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TIZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TIZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLD0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQVDAGMEASLTKCARGKPFHIVTPLLESWPLSQMAGTPVLLKYENVQPTGSFKIRGIGHFCQEVSIASAWVRPHPNSLSSQMVKRGYRHFVCPSGSNAGIATAYAARNLGIPATIVLPESTSLQVVRRLQGEGAEVQLTGKVWDEANLRAQELAKNDGWVNVPPFDHPLIWEGHSSLVHELKAELRTPPGALVLAVGGGGLLAGVSAGLAEVGWQHVPIIAMETQGAHCFNAAVKAGRLVTLPDITSVAKCLGAKTVAARALACTKEFEIFSEVVEDVEAVSAVQRFLDDQRMLVEPACGAALAAIYSGLLGRLQAEGRLRPSLDSVVVIVCGGNNIDSGELQALRAQLGQG", "length": 353, "header": "tr|A0A4X1TIZ3-1|A0A4X1TIZ3_PIG Isoform 1 of L-serine deaminase OS=Sus scrofa OX=9823 GN=SDSL PE=1 SV=1 CANONICAL=A0A4X1TIZ3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TIZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3/entry#A0A4X1TIZ3-1", "sequence": { "sequence": "MQVDAGMEASLTKCARGKPFHIVTPLLESWPLSQMAGTPVLLKYENVQPTGSFKIRGIGHFCQEVSIASAWVRPHPNSLSSQMVKRGYRHFVCPSGSNAGIATAYAARNLGIPATIVLPESTSLQVVRRLQGEGAEVQLTGKVWDEANLRAQELAKNDGWVNVPPFDHPLIWEGHSSLVHELKAELRTPPGALVLAVGGGGLLAGVSAGLAEVGWQHVPIIAMETQGAHCFNAAVKAGRLVTLPDITSVAKCLGAKTVAARALACTKEFEIFSEVVEDVEAVSAVQRFLDDQRMLVEPACGAALAAIYSGLLGRLQAEGRLRPSLDSVVVIVCGGNNIDSGELQALRAQLGQG", "length": 353, "header": "tr|A0A4X1TIZ3-1|A0A4X1TIZ3_PIG Isoform 1 of L-serine deaminase OS=Sus scrofa OX=9823 GN=SDSL PE=1 SV=1 CANONICAL=A0A4X1TIZ3-1" }, "locus": { "chromosome": "14", "start_pos": 38479432, "end_pos": 38471371, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010818.3", "url": "https://www.ensembl.org/id/ENSSSCT00000010818.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010535.3", "url": "https://www.ensembl.org/id/ENSSSCP00000010535.3" } ] } }, { "isoform_ac": "A0A4X1TLD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3/entry#A0A4X1TLD0-1", "sequence": { "sequence": "MQVDAGMEASLTKCARGKPFHIVTPLLESWPLSQMAGTPVLLKYENVQPTGSFKIRGIGHFCQEMVKRGYRHFVCPSGSNAGIATAYAARNLGIPATIVLPESTSLQVVRRLQGEGAEVQLTGKVWDEANLRAQELAKNDGWVNVPPFDHPLIWEGHSSLVHELKAELRTPPGALVLAVGGGGLLAGVSAGLAEVGWQHVPIIAMETQGAHCFNAAVKAGRLVTLPDITSVAKCLGAKTVAARALACTKEFEIFSEVVEDVEAVSAVQRFLDDQRMLVEPACGAALAAIYSGLLGRLQAEGRLRPSLDSVVVIVCGGNNIDSGELQALRAQLGQG", "length": 335, "header": "tr|A0A4X1TLD0-1|A0A4X1TLD0_PIG Computationally mapped isoform of L-serine deaminase OS=Sus scrofa OX=9823 GN=SDSL PE=1 SV=1 CANONICAL=A0A4X1TIZ3-1" }, "locus": { "chromosome": "14", "start_pos": 38479432, "end_pos": 38471371, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062110.2", "url": "https://www.ensembl.org/id/ENSSSCT00000062110.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031329.1", "url": "https://www.ensembl.org/id/ENSSSCP00000031329.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154365", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154365", "resource": "KEGG Pathway" }, { "id": "R-SSC-8849175", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8849175", "resource": "Reactome", "description": "Threonine catabolism" }, { "id": "R-SSC-977347", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-977347", "resource": "Reactome", "description": "Serine metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2L795-1", "protein_name": "L-serine deaminase", "gene_name": "Sdsl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGALVERVRAEPFHRVTPLLESWALSRVAGMPVFLKYENVQPAGSFKIRGIGHFCQQMAMRGCRHLVCSSGGNAGIAAAYSARKLGIPVTIVLPENTSMQVVRRLEGEGAEVQLTGKVWDEANIRAQDLATRDGWVNVSPFDHPLIWEGHASLVRELKESLGTPPGAVVLAVGGGGLLAGVTAGLLEVGWQHVPIIAMETRGAHSFNAALQAGRLVALPDITSVARSLGAKTVAARTLECAKECEVLSEVVEDQEAVRAVQRFLDDERMLVEPACGAALAAVYSGILGRLQAEGRLGPALASIVVIVCGGNNISSQQLQELKTQLGCS", "length": 329 }, "evidence": [ { "id": "A0A4X1TIZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TIZ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8M9PEB6-1", "protein_name": "L-serine ammonia-lyase", "gene_name": "sdsl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSKQNGFHVVTPLLESTGMSKLVGSTVYLKMESSQPAGSFKIRGIGYMCQNVASSNKSRGVICSSGGNAGMATAYAARKLNLPATIVLPLSTPELVAQKLKDQGATVKAVGKVWDDANAEALRLAESEGLTVIHPFNQPLVWKGHSSIVHELKASLPSRPGLIVLSVGGGGLFCGVIEGLDEVGWGDVPVLCMETKGADCFNVALKAKNLVTLPDITSQAVCLGAKTACQQAFEYGKRPTVISEVVTDLQALEAVELFLDEERVLVELACGASLAAVYSGVVNRLQDEGRLPKPLGPLVMIVCGGGSMNMAQLQHLQAVIRK", "length": 322 }, "evidence": [ { "id": "A0A4X1TIZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TIZ3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0X2Z5-1", "protein_name": "L-serine deaminase", "gene_name": "SDSL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAQCGGGEKPFHIVSPLLESLPLSRAAGTQVYMKLENVQPTGSFKIRGVGHLCQEAARKGCQRFVCSSGGNAGMAAAYAARKLGLPATVVVPSSTSPSTVHRLEELGATVEIYGKVWDEANQRALVLAQNKGWASIHPFDHPLLWQGHASLVLELKDALDTKPDAIVLAVGGGGLLAGVVAGLQQVGWLDVPIIAAETWGAHSFHAALKAGHLITLPDITSVAKCLGAKTVSARALQCAQEIQVISEVVEDAEAVRAVESFLDDERMLVQPACGAALALLYSGRLQQLQRDGHLRTPLGRVVVVVCGGSSMTAALLRDLKNQLGLE", "length": 327 }, "evidence": [ { "id": "A0A4X1TIZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TIZ3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q86B06-1", "protein_name": "L-serine dehydratase", "gene_name": "sds", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGLKTTISPDSSFDKIINTKTSPPLHINSPMLESLALSKLFKEENAKVWMKVDALQPSGSFKIRGVGLLCNQLLKEKKSKNEEAHFICSSGGNAGKSVAYAGRKLNVKTTIVLPNTIPEATIEKIKDEGANVIVHGTIWDEANTFALELAEKEGCTDCYIHPFDHPLLWEGHSTMIDEIYQDVQNGVCEKPDVILFSVGGGGMMIGILQGLDRYGWNDIPIVTVETVGSHSFWKSFQEKQLTKLDVSEVTSVIKTLSTRSVCSEAWEISKRFNIKPILVTDRDAVDACLKFVDDERILVEPSCGATLSVLYSKKLSTLLDINSKNILTIVCGGNGTSILQLNDLLQTLPK", "length": 350 }, "evidence": [ { "id": "A0A4X1TIZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TIZ3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8R238-1", "protein_name": "Serine dehydratase-like", "gene_name": "Sdsl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGALAERVGAEPFHRVTPLLESWALSQVAGMPVFLKYENVQIAGSFKIRGIGHFCQQMAKRGCRHLVCSSGGNAGIAAAYSARKLGIPVTIVLPEGTSVQVVRRLEGEGAEVQLTGKVWDEANVKAQELATRDGWVNVSPFDHPLIWEGHASLVRELKESLGTPPGAVVLAVGGGGLLAGVTAGLLEVGWQHVPIVAMETRGAHSFNSALQAGRPVTLPDITSVAKSLGAKTVAARTLECAKECEVLSEVVEDREAVSAVQRFLDDERMLVEPACGAALAAIYSGILWRLQAEGRLSSALASVVVIVCGGNNISSQQLQELKIQLGCS", "length": 329 }, "evidence": [ { "id": "A0A4X1TIZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TIZ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96GA7-1", "protein_name": "Serine dehydratase-like", "gene_name": "SDSL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGPVAEHAKQEPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEMAKKGCRHLVCSSGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLRAQELAKRDGWENVPPFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLAGVVAGLLEVGWQHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQVCKIHSEVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPSLTSVVVIVCGGNNINSRELQALKTHLGQV", "length": 329 }, "evidence": [ { "id": "A0A4X1TIZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TIZ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3" } ], "pmid": "" }, { "name": "L-threonine catabolic process", "id": "GO:0006567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006567", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3" } ], "pmid": "" }, { "name": "L-serine catabolic process", "id": "GO:0006565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006565", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3" } ], "pmid": "" }, { "name": "amino acid metabolic process", "id": "GO:0006520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006520", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3" } ], "pmid": "" }, { "name": "L-serine ammonia-lyase activity", "id": "GO:0003941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003941", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3" } ], "pmid": "" }, { "name": "threonine deaminase activity", "id": "GO:0004794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TIZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19169", "name": "", "equation": "L-serine = pyruvate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19169", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19169" } ] }, { "id": "22108", "name": "", "equation": "L-threonine = 2-oxobutanoate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "22108", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22108" } ] }, { "id": "R-SSC-9014627", "name": "SDS dimers:PXLP convert L-Thr to 2OBUTA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-351990" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9014627", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9014627" } ] }, { "id": "R-SSC-9929460", "name": "SDS dimers:PXLP convert L-Ser to PYR and NH4+", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9929460", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9929460" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-351990", "participant_name": "L-Thr [cytosol]", "crossref": [ { "id": "57926", "database": "ChEBI", "url": "" }, { "id": "ZINC000000895103", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TIZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TIZ3" }, { "id": "PF00291", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00291" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tryptophan synthase beta chain-like PALP", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 334, "start_aa": "His", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TJD4-1", "uniprot_ac": "A0A4X1TJD4", "uniprot_id": "A0A4X1TJD4_PIG", "mass": { "chemical_mass": 35421.0, "monoisotopic_mass": 35421.0 }, "refseq": { "ac": "XP_001928675", "name": "olfactory receptor 4S2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928675" }, "gene_names": [ { "name": "LOC100155381", "type": "synonym", "evidence": [ { "id": "XP_001928675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928675" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TJD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJD4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4S2-like", "type": "synonym", "evidence": [ { "id": "XP_001928675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928675" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJD4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJD4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJD4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJD4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJD4", "locus": {} } ], "crossref": [ { "id": "A0A4X1TJD4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TJD4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155381", "url": "https://www.ncbi.nlm.nih.gov/gene/100155381", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155381", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155381", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CITQMFT", "url": "https://omabrowser.org/oma/group/CITQMFT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TJD4", "url": "https://www.orthodb.org/?gene=A0A4X1TJD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001928675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928675", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TJD4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TJD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVVNNVTEFIFLGLSQDPGMQLMFFPLFLFFYMVIMVGNLLILLMVFSDPQLQTPMYFFLSNLSFVDLAYSSATAPKMIADFVSEKKIISYWGCVTQMFTFHFFGCAEIFVLTVMAFDRYAAICQPLRYTTIMSANACTMLASLSWLGALAHSFVQTLLTFQLPFCNAQVIDHYFCDVHPVLKLACADTTLVNMLVIANSGLISLGCFLILLASYTVILFSLQKRSAESRRKALSTCGSHFTVVTFFFVPCIFIYLRPSTTFPLDKAVSVFYTTITPMLNPLIYTLRNEDVKNAMRRLWCRQVSLKEKQKG", "length": 312, "header": "tr|A0A4X1TJD4-1|A0A4X1TJD4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1TJD4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TJD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJD4/entry#A0A4X1TJD4-1", "sequence": { "sequence": "MEVVNNVTEFIFLGLSQDPGMQLMFFPLFLFFYMVIMVGNLLILLMVFSDPQLQTPMYFFLSNLSFVDLAYSSATAPKMIADFVSEKKIISYWGCVTQMFTFHFFGCAEIFVLTVMAFDRYAAICQPLRYTTIMSANACTMLASLSWLGALAHSFVQTLLTFQLPFCNAQVIDHYFCDVHPVLKLACADTTLVNMLVIANSGLISLGCFLILLASYTVILFSLQKRSAESRRKALSTCGSHFTVVTFFFVPCIFIYLRPSTTFPLDKAVSVFYTTITPMLNPLIYTLRNEDVKNAMRRLWCRQVSLKEKQKG", "length": 312, "header": "tr|A0A4X1TJD4-1|A0A4X1TJD4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1TJD4-1" }, "locus": { "chromosome": "7", "start_pos": 78967683, "end_pos": 78966748, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002888.4", "url": "https://www.ensembl.org/id/ENSSSCT00000002888.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002810.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002810.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJD4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJD4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155381", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155381", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJD4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJD4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJD4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJD4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJD4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TJD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJD4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 63, "end_pos": 65 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TP25-1", "uniprot_ac": "A0A4X1TP25", "uniprot_id": "A0A4X1TP25_PIG", "mass": { "chemical_mass": 84681.0, "monoisotopic_mass": 84681.0 }, "refseq": { "ac": "XP_020925860", "name": "oxysterol-binding protein-related protein 11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925860" }, "gene_names": [ { "name": "OSBPL11", "type": "recommended", "evidence": [ { "id": "A0A4X1TP25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ] }, { "name": "OSBPL11", "type": "synonym", "evidence": [ { "id": "XP_020925860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925860" } ] } ], "protein_names": [ { "name": "Oxysterol-binding protein", "type": "recommended", "evidence": [ { "id": "A0A4X1TP25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25/entry#names_and_taxonomy" } ] }, { "name": "oxysterol-binding protein-related protein 11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020925860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925860" } ] } ], "function": [ { "annotation": "Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage. Weakly binds 25-hydroxycholesterol. Interacts with OSBPL9 to function as lipid transfer proteins. Together they form a heterodimer that localizes at the ER-trans-Golgi membrane contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) between the two organelles, a step that is critical for sphingomyelin synthesis in the Golgi complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJH3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJH3#function" }, { "database": "UniProtKB", "id": "ARBA00058048", "url": "https://www.uniprot.org/uniprotkb/ARBA00058048#function" }, { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OSBPL11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25", "locus": { "chromosome": "13", "start_pos": 134807146, "end_pos": 134718450, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026753", "url": "https://www.ensembl.org/id/ENSSSCG00000026753" } ] } } ], "crossref": [ { "id": "cd13291", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13291", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100623596", "url": "https://www.ncbi.nlm.nih.gov/gene/100623596", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623596", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623596", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CDHKEDD", "url": "https://omabrowser.org/oma/group/CDHKEDD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TP25", "url": "https://www.orthodb.org/?gene=A0A4X1TP25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9013407", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020925860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925860", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "81667", "url": "https://www.rhea-db.org/rhea/81667", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TJH3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TJH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TP25-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFEVKMQGGEPLSTMKVSESEGRLEGLATAVTPNKNSSNSSCGGGISSSSSGSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSGNSPISQRRPSQNAISFFNVGHSKLQSVSKRANLPPDHLVEVREMMSHAEGQQRDLIRRIECLPASGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKIPLSNHYKNEADQPFAAEQSKPVAVPEEQCVAESGLLTREPEEINADDEVEDTCDNKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIGITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVASSVISSSTQAGTNHAPPSEETLSQVGSDCYTVRFVAEQVSHHPPVSGFYAECAERKMCVNAHVWTKSKFLGMSIGVTMVGEGVLSLLEHGEEYTFSLPCAYARSILTVPWVELGGKISVNCAKTGYSASITFHTKPFYGGKLHRVTGEVKHNITNTVVCKVQGEWNSVLEFTYSNGETKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKRTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWKIIPTTQPAE", "length": 757, "header": "tr|A0A4X1TP25-1|A0A4X1TP25_PIG Isoform 1 of Oxysterol-binding protein OS=Sus scrofa OX=9823 GN=OSBPL11 PE=3 SV=1 CANONICAL=A0A4X1TP25-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TJH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25/entry#A0A4X1TJH3-1", "sequence": { "sequence": "MDFEVKMQGGEPLSTMKVSESEGRLEGLATAVTPNKNSSNSSCGGGISSSSSGSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKMMSHAEGQQRDLIRRIECLPASGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKIPLSNHYKNEADQPFAAEQSKPVAVPEEQCVAESGLLTREPEEINADDEVEDTCDNKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIGITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVASSVISSSTQAGTNHAPPSEETLSQVGSDCYTVRFVAEQVSHHPPVSGFYAECAERKMCVNAHVWTKSKFLGMSIGVTMVGEGVLSLLEHGEEYTFSLPCAYARSILTVPWVELGGKISVNCAKTGYSASITFHTKPFYGGKLHRVTGEVKHNITNTVVCKVQGEWNSVLEFTYSNGETKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKRTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWKIIPTTQPAE", "length": 698, "header": "tr|A0A4X1TJH3-1|A0A4X1TP25_PIG Computationally mapped isoform of Oxysterol-binding protein OS=Sus scrofa OX=9823 GN=OSBPL11 PE=3 SV=1 CANONICAL=A0A4X1TP25-1" }, "locus": { "chromosome": "13", "start_pos": 134805499, "end_pos": 134719194, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048458.2", "url": "https://www.ensembl.org/id/ENSSSCT00000048458.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053029.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053029.1" } ] } }, { "isoform_ac": "A0A4X1TP25-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25/entry#A0A4X1TP25-1", "sequence": { "sequence": "MDFEVKMQGGEPLSTMKVSESEGRLEGLATAVTPNKNSSNSSCGGGISSSSSGSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSGNSPISQRRPSQNAISFFNVGHSKLQSVSKRANLPPDHLVEVREMMSHAEGQQRDLIRRIECLPASGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKIPLSNHYKNEADQPFAAEQSKPVAVPEEQCVAESGLLTREPEEINADDEVEDTCDNKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIGITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVASSVISSSTQAGTNHAPPSEETLSQVGSDCYTVRFVAEQVSHHPPVSGFYAECAERKMCVNAHVWTKSKFLGMSIGVTMVGEGVLSLLEHGEEYTFSLPCAYARSILTVPWVELGGKISVNCAKTGYSASITFHTKPFYGGKLHRVTGEVKHNITNTVVCKVQGEWNSVLEFTYSNGETKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKRTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWKIIPTTQPAE", "length": 757, "header": "tr|A0A4X1TP25-1|A0A4X1TP25_PIG Isoform 1 of Oxysterol-binding protein OS=Sus scrofa OX=9823 GN=OSBPL11 PE=3 SV=1 CANONICAL=A0A4X1TP25-1" }, "locus": { "chromosome": "13", "start_pos": 134805499, "end_pos": 134719194, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081516.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081516.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062186.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062186.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJH3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJH3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623596", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623596", "resource": "KEGG Pathway" }, { "id": "R-SSC-9013407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013407", "resource": "Reactome", "description": "RHOH GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZEV4-1", "protein_name": "Oxysterol-binding protein", "gene_name": "OSBPL11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQCADPAAAVKGPEGEGKAEPAAAGKSGGRGAKGWQYSDHMENICGYLMKYTNLVTGWQYRFFVLNNDAGLLEYFVNEQSRHLKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASQGSINSPGLQRRPSQNAVSFFNVGHHRLPAGKRGPILQPDHLVDVREMMSQAEGQQRDLIRSIECLPVSGHLTSLDQDLLMLKATSMATMNCLNDCFHILQLQHASQQKGSLPAGTTISWLEPKISLSNHFKNGAAQNFPAEINKPASVREEQSNAEPCQLTREPEEINPDEELEDLCDDKEDDLGGVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATPEERMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVATDGGSNISAHSEQIALSKDLEGQAESDYYTVKFVAEQVSHHPPVSGFYAECVERKMCVNAHVWTKSKFLGMSIGVTMVGEGLLSLLEHEEEYTFSLPCAYARSILTVPWVELGGKVNINCAKTGYSASINFHTKPFYGGKLHRVTGEVKQNATNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLSVTRKRVRPIEKQGPFESRRLWQHVTESLRDGDIDKATEHKRALEERQRNEERLRAETETPWCTKYFIKEGDGWVYHKPLWRAVSAVQTQQMDAN", "length": 734 }, "evidence": [ { "id": "A0A4X1TP25", "url": "https://omabrowser.org/oma/group/A0A4X1TP25/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8CI95-1", "protein_name": "Oxysterol-binding protein-related protein 11", "gene_name": "Osbpl11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGGEPASVMKVSESEGKLEGLATAVTPNKNSGNSSCGGAISSSSSNSSRGGSAKGWQYSDHMESVNGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSGNSPISQRRPSQNAMSFFNVGHSKLQSVNKRAHLHPDHLVEVREMMSHAEGQQRDLIRRIECLPASGLLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGALPSGTTIEWLEPKIPLSNHYKNGAEQPFATEPNKPMGAPEAQCVAESGVLAREPEDISADDEVEDTCDNKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIGITNGATPEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVASGVSSSSSTPAITDHAPLPEEAPTQSVSDCYTVRFVAEQVSHHPPVSGFYAECAERKMCVNAHVWTKSKFLGMSIGVTMVGEGVLCLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKYNLTNTVVCRVQGEWNSVLEFTYSNGETKFVDLAKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKRSLEERQRTEERLRTETGTPWKTKYFIKEGDGWVYHKPLWKGIPSQPAE", "length": 751 }, "evidence": [ { "id": "A0A4X1TP25", "url": "https://omabrowser.org/oma/group/A0A4X1TP25/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXB4-1", "protein_name": "Oxysterol-binding protein-related protein 11", "gene_name": "OSBPL11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGGEPVSTMKVSESEGKLEGQATAVTPNKNSSCGGGISSSSSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSNSPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMSHAEGQQRDLIRRIECLPTSGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKISLSNHYKNGADQPFATDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWKIIPTTQPAE", "length": 747 }, "evidence": [ { "id": "A0A4X1TP25", "url": "https://omabrowser.org/oma/group/A0A4X1TP25/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "endoplasmic reticulum-trans-Golgi network membrane contact site", "id": "GO:0160258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160258", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "phospholipid transfer to membrane", "id": "GO:0006649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006649", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "lysosomal membrane organization", "id": "GO:0097212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097212", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "sterol binding", "id": "GO:0032934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032934", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" }, { "name": "phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity", "id": "GO:0160270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "81667", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "81667", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81667" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TP25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP25" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 166, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 37, "end_pos": 39 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 632, "end_pos": 634 }, { "start_pos": 690, "end_pos": 692 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TJQ9-1", "uniprot_ac": "A0A4X1TJQ9", "uniprot_id": "A0A4X1TJQ9_PIG", "mass": { "chemical_mass": 12057.0, "monoisotopic_mass": 12057.0 }, "refseq": { "ac": "XP_003127104", "name": "gamma-secretase subunit PEN-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003127104" }, "gene_names": [ { "name": "PSENEN", "type": "recommended", "evidence": [ { "id": "A0A4X1TJQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ] }, { "name": "PSENEN", "type": "synonym", "evidence": [ { "id": "XP_003127104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003127104" } ] } ], "protein_names": [ { "name": "Gamma-secretase subunit PEN-2", "type": "recommended", "evidence": [ { "id": "A0A4X1TJQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9/entry#names_and_taxonomy" } ] }, { "name": "gamma-secretase subunit PEN-2", "type": "synonym", "evidence": [ { "id": "XP_003127104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003127104" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PSENEN", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9", "locus": { "chromosome": "6", "start_pos": 45174102, "end_pos": 45171825, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000032059", "url": "https://www.ensembl.org/id/ENSSSCG00000032059" } ] } } ], "crossref": [ { "id": "A0A4X1TJQ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TJQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100518735", "url": "https://www.ncbi.nlm.nih.gov/gene/100518735", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518735", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518735", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KLYLCKW", "url": "https://omabrowser.org/oma/group/KLYLCKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TJQ9", "url": "https://www.orthodb.org/?gene=A0A4X1TJQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16318:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16318:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10251", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10251", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1251985", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1251985", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-193692", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3928665", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3928665", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9839383", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9839383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003127104", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003127104", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TJQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFLVPAYTEQSQIKGYVWRSAVGFLFWVIILTTWITIFQIYRPRWGALGDYLSFTIPLGTP", "length": 101, "header": "tr|A0A4X1TJQ9-1|A0A4X1TJQ9_PIG Isoform 1 of Gamma-secretase subunit PEN-2 OS=Sus scrofa OX=9823 GN=PSENEN PE=3 SV=1 CANONICAL=A0A4X1TJQ9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TJQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9/entry#A0A4X1TJQ9-1", "sequence": { "sequence": "MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFLVPAYTEQSQIKGYVWRSAVGFLFWVIILTTWITIFQIYRPRWGALGDYLSFTIPLGTP", "length": 101, "header": "tr|A0A4X1TJQ9-1|A0A4X1TJQ9_PIG Isoform 1 of Gamma-secretase subunit PEN-2 OS=Sus scrofa OX=9823 GN=PSENEN PE=3 SV=1 CANONICAL=A0A4X1TJQ9-1" }, "locus": { "chromosome": "6", "start_pos": 45173972, "end_pos": 45172806, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062978.2", "url": "https://www.ensembl.org/id/ENSSSCT00000062978.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047698.1", "url": "https://www.ensembl.org/id/ENSSSCP00000047698.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518735", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518735", "resource": "KEGG Pathway" }, { "id": "R-SSC-1251985", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1251985", "resource": "Reactome", "description": "Nuclear signaling by ERBB4" }, { "id": "R-SSC-193692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193692", "resource": "Reactome", "description": "Regulated proteolysis of p75NTR" }, { "id": "R-SSC-3928665", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3928665", "resource": "Reactome", "description": "EPH-ephrin mediated repulsion of cells" }, { "id": "R-SSC-9839383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9839383", "resource": "Reactome", "description": "TGFBR3 PTM regulation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5G235-1", "protein_name": "Gamma-secretase subunit PEN-2", "gene_name": "PSENEN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFIVPAYTEQSQIKGYVWRSAVGFFLWVIVLSTWITIFQIYRPRWGALGDYLSFTIPLGTP", "length": 101 }, "evidence": [ { "id": "A0A4X1TJQ9", "url": "https://omabrowser.org/oma/group/A0A4X1TJQ9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6QI68-1", "protein_name": "Gamma-secretase subunit PEN-2", "gene_name": "Psenen", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFKEAFFAPAYTEQSQIKGYVWRSAVGFLFWVIVLTTWITIFQIYRPRWGALGDYLSFTIPLGTP", "length": 101 }, "evidence": [ { "id": "A0A4X1TJQ9", "url": "https://omabrowser.org/oma/group/A0A4X1TJQ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86BE9-1", "protein_name": "Gamma-secretase subunit pen-2", "gene_name": "pen-2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDISKAPNPRKLELCRKYFFAGFAFLPFVWAINVCWFFTEAFHKPPFSEQSQIKRYVIYSAVGTLFWLIVLTAWIIIFQTNRTAWGATADYMSFIIPLGSA", "length": 101 }, "evidence": [ { "id": "A0A4X1TJQ9", "url": "https://omabrowser.org/oma/group/A0A4X1TJQ9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8JHF0-1", "protein_name": "Gamma-secretase subunit PEN-2", "gene_name": "psenen", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNLERIPNEEKLSLCRRYYLGGFAFLPFLWLVNILWFFKEAFLKPAYTEQPQIKSYVKKSALGLLLWVAVLTTWITVFQHFRAQWGEVGDYLSFTIPLGTA", "length": 101 }, "evidence": [ { "id": "A0A4X1TJQ9", "url": "https://omabrowser.org/oma/group/A0A4X1TJQ9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CQR7-1", "protein_name": "Gamma-secretase subunit PEN-2", "gene_name": "Psenen", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFLAPAYTEQSQIKGYVWRSAVGFLFWVIILATWITIFQIYRPRWGALGDYLSFTIPLGTP", "length": 101 }, "evidence": [ { "id": "A0A4X1TJQ9", "url": "https://omabrowser.org/oma/group/A0A4X1TJQ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZ42-1", "protein_name": "Gamma-secretase subunit PEN-2", "gene_name": "PSENEN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFLVPAYTEQSQIKGYVWRSAVGFLFWVIVLTSWITIFQIYRPRWGALGDYLSFTIPLGTP", "length": 101 }, "evidence": [ { "id": "A0A4X1TJQ9", "url": "https://omabrowser.org/oma/group/A0A4X1TJQ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "pmid": "" }, { "name": "gamma-secretase complex", "id": "GO:0070765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070765", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "membrane protein ectodomain proteolysis", "id": "GO:0006509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006509", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "pmid": "" }, { "name": "Notch receptor processing", "id": "GO:0007220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007220", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "pmid": "" }, { "name": "membrane protein intracellular domain proteolysis", "id": "GO:0031293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031293", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "pmid": "" }, { "name": "amyloid-beta formation", "id": "GO:0034205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034205", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "pmid": "" }, { "name": "endopeptidase activator activity", "id": "GO:0061133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061133", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TKA7-1", "uniprot_ac": "A0A4X1TKA7", "uniprot_id": "A0A4X1TKA7_PIG", "mass": { "chemical_mass": 60909.0, "monoisotopic_mass": 60909.0 }, "refseq": { "ac": "XP_020925161", "name": "lariat debranching enzyme", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925161" }, "gene_names": [ { "name": "DBR1", "type": "recommended", "evidence": [ { "id": "A0A4X1TKA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7" } ] }, { "name": "DBR1", "type": "synonym", "evidence": [ { "id": "XP_020925161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925161" } ] } ], "protein_names": [ { "name": "Lariat debranching enzyme", "type": "recommended", "evidence": [ { "id": "A0A4X1TKA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7/entry#names_and_taxonomy" } ] }, { "name": "lariat debranching enzyme", "type": "synonym", "evidence": [ { "id": "XP_020925161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925161" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKA7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DBR1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7", "locus": { "chromosome": "13", "start_pos": 78958218, "end_pos": 78970137, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031098", "url": "https://www.ensembl.org/id/ENSSSCG00000031098" } ] } } ], "crossref": [ { "id": "A0A4X1TKA7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TKA7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00844", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00844", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "106505697", "url": "https://www.ncbi.nlm.nih.gov/gene/106505697", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007708", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007708", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:106505697", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106505697", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GIDDPLC", "url": "https://omabrowser.org/oma/group/GIDDPLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TKA7", "url": "https://www.orthodb.org/?gene=A0A4X1TKA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12849:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12849:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05011", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05011", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020925161", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925161", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TKA7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TKA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVAVAGCCHGELDKIYETLALAERRGPGPIDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTVFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYNASTIRSIYHVRNIEVYKLKQLKQPMDIFLSHDWPRSIYHYGNKKQLLKTKSFFRQEVENNTLGSPAASELLEHLKPTYWFSAHLHVKFAALMQHQVKDKEQSAKATKFLALDKCLPHRDFLQVIEIQHDPSAPEYLEYDTEWLAILRATNDLINVTERPWNMPENNGLHTRWDYSATKEAMNEVMEKLNHDLKVPCNFSVTAACYDPSKPQTQMQLVHRISPQTTEFCAQLGITDINVRLQKAKEEQHLCGDYEGQDAVESNDSGEDPSEYNTDTSALSSINPDEIMLDEEEDYEDSIVSAHSDTNTPSAEPSDQASDFSTSFSDVRILPSSMIVSSDDTSGSPVGKEGNSGEPLELGDGKVPLKRLSNEHEPEQRKKIKRRNQAIYAAVDDDDTA", "length": 539, "header": "tr|A0A4X1TKA7-1|A0A4X1TKA7_PIG Isoform 1 of Lariat debranching enzyme OS=Sus scrofa OX=9823 GN=DBR1 PE=3 SV=1 CANONICAL=A0A4X1TKA7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TKA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7/entry#A0A4X1TKA7-1", "sequence": { "sequence": "MRVAVAGCCHGELDKIYETLALAERRGPGPIDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTVFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYNASTIRSIYHVRNIEVYKLKQLKQPMDIFLSHDWPRSIYHYGNKKQLLKTKSFFRQEVENNTLGSPAASELLEHLKPTYWFSAHLHVKFAALMQHQVKDKEQSAKATKFLALDKCLPHRDFLQVIEIQHDPSAPEYLEYDTEWLAILRATNDLINVTERPWNMPENNGLHTRWDYSATKEAMNEVMEKLNHDLKVPCNFSVTAACYDPSKPQTQMQLVHRISPQTTEFCAQLGITDINVRLQKAKEEQHLCGDYEGQDAVESNDSGEDPSEYNTDTSALSSINPDEIMLDEEEDYEDSIVSAHSDTNTPSAEPSDQASDFSTSFSDVRILPSSMIVSSDDTSGSPVGKEGNSGEPLELGDGKVPLKRLSNEHEPEQRKKIKRRNQAIYAAVDDDDTA", "length": 539, "header": "tr|A0A4X1TKA7-1|A0A4X1TKA7_PIG Isoform 1 of Lariat debranching enzyme OS=Sus scrofa OX=9823 GN=DBR1 PE=3 SV=1 CANONICAL=A0A4X1TKA7-1" }, "locus": { "chromosome": "13", "start_pos": 78970000, "end_pos": 78959354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059701.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059701.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056429.1", "url": "https://www.ensembl.org/id/ENSSSCP00000056429.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKA7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:106505697", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106505697", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5ZLM2-1", "protein_name": "Lariat debranching enzyme", "gene_name": "DBR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKVAVAGCCHGALDKMYETLELLQRRHNVRPDLLLCCGDFQAVRNEADLRCMAVPAKYRHMQTFYRYYSGEKKAPVLTVFIGGNHEASNHLQELPYGGWVAPNIYYLGYAGVVRFRGVRIGGISGIFKSHDYRKGHFECPPYNQQTIRSAYHVRNIEVFKLKQLKHPMDIFMSHDWPQSIYHYGNKKQLLKMKSFFRQEVESNTLGSPAASELLQHLKPNYWFSAHLHVKFAAFMQHETKSKEELPKATKFLALDKCLPHRDFLQIIDIEHDPTAGDSLEYDAEWIAVLKATNSLINVTQSSWSVPENNGLHAKWDYSATEEAIKEVLEELNHNLKIPCNFTLTTTCYDPSKPQKNMEPVHTINPQTTEFCAQFGLTDINDRIQQVKEEGSVRGEYEEEEEEMDSSGSAEEPSEYNTDNSGLSSINPDEIMLDDEGGDEDLSTCSVDPSPDHPPEFSASFSDIRIMPDSMAVSSDDAMDSTNEELEKSGVNKQVEEKSLNERPLKRVGGSENGNSGIKIKRRNQAIYAAEDEDEAK", "length": 536 }, "evidence": [ { "id": "A0A4X1TKA7", "url": "https://omabrowser.org/oma/group/A0A4X1TKA7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q923B1-1", "protein_name": "Lariat debranching enzyme", "gene_name": "Dbr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRVAVAGCCHGELDKIYETLALAERRGSGPVDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTIFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYNSSTIRSIYHVRNIEVYKLKQLKQPVHIFLSHDWPRNIYHYGNKKQLLKTKSFFRQEVENSTLGSPAASELLEHLQPAYWFSAHLHVKFAALMQHQATDKDQAGKETKFLALDKCLPHRDFLQVLEIEHDPSAPEYLEYDVEWLTVLRATDDLINVTGGLWNMPEDNGLHTRWDYSATEETMKEVMEKLNHDPKVPCNFTMTAACYDPSKPQTQVKLVHRINPQTTEFCAQLGITDINVMIQKAREEEHHQCGEYEQQGDPGTEESEEDRSEYNTDTSALSSINPDEIMLDEEEEEEEEEEEAVSAHSDMNTPSVEPASDQASDLSTSFSDIRNLPSSMFVSSDDASRSPASGEGKCGETVESGDEKDLAKFPLKRLSDEHEPEQRKKIKRRNQAIYAAVDDGDASAE", "length": 550 }, "evidence": [ { "id": "A0A4X1TKA7", "url": "https://omabrowser.org/oma/group/A0A4X1TKA7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UK59-1", "protein_name": "Lariat debranching enzyme", "gene_name": "DBR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVAVAGCCHGELDKIYETLALAERRGPGPVDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTLFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYNSSTIRSIYHVRNIEVYKLKQLKQPIDIFLSHDWPRSIYHYGNKKQLLKTKSFFRQEVENNTLGSPAASELLEHLKPTYWFSAHLHVKFAALMQHQAKDKGQTARATKFLALDKCLPHRDFLQILEIEHDPSAPDYLEYDIEWLTILRATDDLINVTGRLWNMPENNGLHARWDYSATEEGMKEVLEKLNHDLKVPCNFSVTAACYDPSKPQTQMQLIHRINPQTTEFCAQLGIIDINVRLQKSKEEHHVCGEYEEQDDVESNDSGEDQSEYNTDTSALSSINPDEIMLDEEEDEDSIVSAHSGMNTPSVEPSDQASEFSASFSDVRILPGSMIVSSDDTVDSTIDREGKPGGTVESGNGEDLTKVPLKRLSDEHEPEQRKKIKRRNQAIYAAVDDDDDDAA", "length": 544 }, "evidence": [ { "id": "A0A4X1TKA7", "url": "https://omabrowser.org/oma/group/A0A4X1TKA7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VSD7-1", "protein_name": "Lariat debranching enzyme", "gene_name": "ldbr", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKIAVEGCAHGELERIYDTIEGIEKVGGTKIDLLLCCGDFQSTRNLEDLQTMAVPKKYLDMCSFYKYYSGELVAPVLTIFIGGNHEASNYLQELPYGGWVAPNIYYLGYAGVVNVNGVRIAGISGIFKGHDFLRGHHEFPPYTDSTCRSVYHVRQLEVFRLKQISGRVDIFLSHDWPTGIYEYGNKAQLLRKKPFFAADMESGKLGSQPLEELLKAVQPAYWFAAHLHCKFAALVPHNHSQKLGDAESSSSSSSSEDEDEEREKVKKAAPVPPPSKSVPVTKFLALDKCLPRRAFLQVVEVPSDPIEGTPRLEYDAEWLAILHSTNHLISVKENYYYLPGKKAGEFTERSNFTPTEEELEAVTAKFQKLQVPENFERTVPAFDPAEQSDYKHMFVDQPKVQLNPQSNTFCATLGIDDPLCLVLLANGLDLPAVGATECKDRETKSSKLQAVEEDVAEPLVTPTKRKLNLSLPAPTTAAADTTDENVIDLPEEEAEEAIIATETPHVEEPASVPASPNVKKLKRRNQNIYQAQED", "length": 534 }, "evidence": [ { "id": "A0A4X1TKA7", "url": "https://omabrowser.org/oma/group/A0A4X1TKA7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA lariat debranching enzyme activity", "id": "GO:0008419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008419", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKA7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKA7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKA7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKA7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7" } ], "pmid": "" }, { "name": "RNA fragment catabolic process", "id": "GO:0000292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000292", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKA7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TKA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKA7" }, { "id": "SM01124", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01124" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lariat debranching enzyme C-terminal", "eco_id": "ECO_0000259", "start_pos": 235, "end_pos": 380, "start_aa": "Met", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 }, { "start_pos": 202, "end_pos": 204 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 405, "end_pos": 407 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TPW0-1", "uniprot_ac": "A0A4X1TPW0", "uniprot_id": "A0A4X1TPW0_PIG", "mass": { "chemical_mass": 18337.0, "monoisotopic_mass": 18337.0 }, "refseq": { "ac": "XP_003121759", "name": "complexin-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121759" }, "gene_names": [ { "name": "CPLX4", "type": "recommended", "evidence": [ { "id": "A0A4X1TPW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ] }, { "name": "CPLX4", "type": "synonym", "evidence": [ { "id": "XP_003121759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121759" } ] } ], "protein_names": [ { "name": "Complexin 4", "type": "synonym", "evidence": [ { "id": "A0A4X1TPW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0/entry#names_and_taxonomy" } ] }, { "name": "complexin-4", "type": "synonym", "evidence": [ { "id": "XP_003121759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121759" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CPLX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0", "locus": { "chromosome": "1", "start_pos": 161675730, "end_pos": 161634735, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004909", "url": "https://www.ensembl.org/id/ENSSSCG00000004909" } ] } } ], "crossref": [ { "id": "A0A4X1TPW0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TPW0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22809", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22809", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523764", "url": "https://www.ncbi.nlm.nih.gov/gene/100523764", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523764", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523764", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SLMGQFQ", "url": "https://omabrowser.org/oma/group/SLMGQFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TPW0", "url": "https://www.orthodb.org/?gene=A0A4X1TPW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16705:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16705:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003121759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121759", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TKE0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TKE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TPW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFLMKTMISNQVKNLGLGGGSEEKKEEGGTSDPAAAHGMTREEYEEYQKQVIEEKMERDAAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGDDVDLPEDLRKMVNEDQEEEEDKDSILGQLQNLQNMDLDTIKEKAQATFTEIKQTAEQKCSVM", "length": 160, "header": "tr|A0A4X1TPW0-1|A0A4X1TPW0_PIG Isoform 1 of Complexin 4 OS=Sus scrofa OX=9823 GN=CPLX4 PE=1 SV=1 CANONICAL=A0A4X1TPW0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TKE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0/entry#A0A4X1TKE0-1", "sequence": { "sequence": "MAFLMKTMISNQVKNLGLGGGSEEKKEEGGTSDPAAAHGMTREEYEEYQKQVIEEKMERDAAFTQKKAERACLRVHLREKYRLPKGTENSLHRCLSSQEGCR", "length": 102, "header": "tr|A0A4X1TKE0-1|A0A4X1TKE0_PIG Computationally mapped isoform of Complexin 4 OS=Sus scrofa OX=9823 GN=CPLX4 PE=1 SV=1 CANONICAL=A0A4X1TPW0-1" }, "locus": { "chromosome": "1", "start_pos": 161675727, "end_pos": 161634934, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087743.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087743.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060165.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060165.1" } ] } }, { "isoform_ac": "A0A4X1TPW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0/entry#A0A4X1TPW0-1", "sequence": { "sequence": "MAFLMKTMISNQVKNLGLGGGSEEKKEEGGTSDPAAAHGMTREEYEEYQKQVIEEKMERDAAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGDDVDLPEDLRKMVNEDQEEEEDKDSILGQLQNLQNMDLDTIKEKAQATFTEIKQTAEQKCSVM", "length": 160, "header": "tr|A0A4X1TPW0-1|A0A4X1TPW0_PIG Isoform 1 of Complexin 4 OS=Sus scrofa OX=9823 GN=CPLX4 PE=1 SV=1 CANONICAL=A0A4X1TPW0-1" }, "locus": { "chromosome": "1", "start_pos": 161661730, "end_pos": 161634934, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005416.3", "url": "https://www.ensembl.org/id/ENSSSCT00000005416.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005281.1", "url": "https://www.ensembl.org/id/ENSSSCP00000005281.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523764", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523764", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y5C1-1", "protein_name": "Complexin 4", "gene_name": "CPLX4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAFLMKSMLSNQVKNLGLGGGGEESKEESTPSDPAAAAGMTREEYEEYQKQMVEEKMERDAAFAQKKAERACLRVHLREKYRLPKSELDENQIQMAGDDVGLPEDLQKMVAEDQIEEEDKDSILGQLQNIQNMDMDAIKEKAQATFTEIKQAAEQKCSVM", "length": 160 }, "evidence": [ { "id": "A0A4X1TPW0", "url": "https://omabrowser.org/oma/group/A0A4X1TPW0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZM85-1", "protein_name": "Complexin 4", "gene_name": "Cplx4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFFVKNMISNQVKNLGFGGGSEEKKEEGGTSDPAAAKGMTREEYEEYQKQMIEEKMERDAAFTQKKAERACLRVHLRDKYRLPKSEMDETQIQLAGDDVDLPEDLRKMVDEDQDEEEEKDSILGQLQNLQNMDLDTIKEKAQATFTEIKQSAEQKCSVM", "length": 160 }, "evidence": [ { "id": "A0A4X1TPW0", "url": "https://omabrowser.org/oma/group/A0A4X1TPW0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BEG6-1", "protein_name": "Complexin 4", "gene_name": "CPLX4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFLMKTMISNQVKNLGLGGGSEEKKEEGGASDPAAAQGMSREEYEEYQKQIIEEKMERDAAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGDDVDLPEDLRKMVDEDQEEEEDKDSILGQLQNLQNMDLDAIKEKAQATFSEIKQTAEQKCAVM", "length": 160 }, "evidence": [ { "id": "A0A4X1TPW0", "url": "https://omabrowser.org/oma/group/A0A4X1TPW0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7Z7G2-1", "protein_name": "Complexin-4", "gene_name": "CPLX4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFLMKSMISNQVKNLGFGGGSEENKEEGGASDPAAAQGMTREEYEEYQKQMIEEKMERDAAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGDDVDLPEDLRKMVDEDQEEEEDKDSILGQIQNLQNMDLDTIKEKAQATFTEIKQTAEQKCSVM", "length": 160 }, "evidence": [ { "id": "A0A4X1TPW0", "url": "https://omabrowser.org/oma/group/A0A4X1TPW0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80WM3-1", "protein_name": "Complexin-4", "gene_name": "Cplx4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFFVKNMISNQVKNLGFGGGSEEKKEEGGTSDPAAAKGMTREEYEEYQKQMIEEKMERDAAFTQKKAERACLRVHLRDKYRLPKSEMDETQIQLAGDDVDLPEDLRKMVDEDQDEEEEKDSILGQLQNLQNMDLDTIKEKAQATFTEIKQSAEQKCSVM", "length": 160 }, "evidence": [ { "id": "A0A4X1TPW0", "url": "https://omabrowser.org/oma/group/A0A4X1TPW0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ], "pmid": "" }, { "name": "neurotransmitter transport", "id": "GO:0006836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006836", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031630", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ], "pmid": "" }, { "name": "synaptic vesicle exocytosis", "id": "GO:0016079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016079", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPW0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPW0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TKG2-1", "uniprot_ac": "A0A4X1TKG2", "uniprot_id": "A0A4X1TKG2_PIG", "mass": { "chemical_mass": 16460.0, "monoisotopic_mass": 16460.0 }, "refseq": { "ac": "NP_001231278", "name": "eukaryotic translation initiation factor 1A, Y-linked", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231278" }, "gene_names": [ { "name": "EIF1AY", "type": "recommended", "evidence": [ { "id": "A0A4X1TKG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKG2" } ] }, { "name": "EIF1AY", "type": "synonym", "evidence": [ { "id": "NP_001231278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231278" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 4C", "type": "recommended", "evidence": [ { "id": "A0A4X1TKG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKG2/entry#names_and_taxonomy" } ] }, { "name": "eukaryotic translation initiation factor 1A, Y-chromosomal", "type": "synonym", "evidence": [ { "id": "NP_001231278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231278" } ] }, { "name": "eukaryotic translation initiation factor 1A, Y-linked", "type": "synonym", "evidence": [ { "id": "NP_001231278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231278" } ] } ], "function": [ { "annotation": "Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKG2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKG2#function" }, { "database": "UniProtKB", "id": "RU004365", "url": "https://www.uniprot.org/uniprotkb/RU004365#function" }, { "database": "UniProtKB", "id": "ARBA00045454", "url": "https://www.uniprot.org/uniprotkb/ARBA00045454#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKG2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKG2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EIF1AY", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKG2", "locus": { "chromosome": "Y", "start_pos": 9687353, "end_pos": 9704479, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037509", "url": "https://www.ensembl.org/id/ENSSSCG00000037509" } ] } } ], "crossref": [ { "id": "A0A4X1TKG2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TKG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100625415", "url": "https://www.ncbi.nlm.nih.gov/gene/100625415", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006196", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006196", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100625415", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625415", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TKG2", "url": "https://www.orthodb.org/?gene=A0A4X1TKG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21668", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21668", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001231278", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231278", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TKG2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TKG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGPGDDDEIQFDDIGDDDEDIDDI", "length": 144, "header": "tr|A0A4X1TKG2-1|A0A4X1TKG2_PIG Isoform 1 of Eukaryotic translation initiation factor 4C OS=Sus scrofa OX=9823 GN=EIF1AY PE=3 SV=1 CANONICAL=A0A4X1TKG2-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TKG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKG2/entry#A0A4X1TKG2-1", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGPGDDDEIQFDDIGDDDEDIDDI", "length": 144, "header": "tr|A0A4X1TKG2-1|A0A4X1TKG2_PIG Isoform 1 of Eukaryotic translation initiation factor 4C OS=Sus scrofa OX=9823 GN=EIF1AY PE=3 SV=1 CANONICAL=A0A4X1TKG2-1" }, "locus": { "chromosome": "Y", "start_pos": 9704291, "end_pos": 9688355, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061389.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061389.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059165.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059165.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "ssc:100625415", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625415", "resource": "KEGG Pathway" }, { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-SSC-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKG2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKG2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKG2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKG2" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKG2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TKG2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TKG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A4X1TLK4-1", "uniprot_ac": "A0A4X1TLK4", "uniprot_id": "A0A4X1TLK4_PIG", "mass": { "chemical_mass": 90839.0, "monoisotopic_mass": 90839.0 }, "refseq": { "ac": "XP_003123014", "name": "spondin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123014" }, "gene_names": [ { "name": "SPON1", "type": "recommended", "evidence": [ { "id": "A0A4X1TLK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4" } ] }, { "name": "SPON1", "type": "synonym", "evidence": [ { "id": "XP_003123014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123014" } ] } ], "protein_names": [ { "name": "Spondin-1", "type": "recommended", "evidence": [ { "id": "A0A4X1TLK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4/entry#names_and_taxonomy" } ] }, { "name": "F-spondin", "type": "synonym", "evidence": [ { "id": "A0A4X1TLK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4/entry#names_and_taxonomy" } ] }, { "name": "spondin-1", "type": "synonym", "evidence": [ { "id": "XP_003123014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123014" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLK4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SPON1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4", "locus": { "chromosome": "2", "start_pos": 44967986, "end_pos": 45299677, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013393", "url": "https://www.ensembl.org/id/ENSSSCG00000013393" } ] } } ], "crossref": [ { "id": "A0A4X1TLK4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TLK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08544", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08544", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100516954", "url": "https://www.ncbi.nlm.nih.gov/gene/100516954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516954", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516954", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IPRIEGC", "url": "https://omabrowser.org/oma/group/IPRIEGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TLK4", "url": "https://www.orthodb.org/?gene=A0A4X1TLK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11311", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11311", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11311:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11311:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06468", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06468", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5173214", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5173214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003123014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123014", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TLB3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLK4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLSPASVKLSGSPALLALALPLAAALAFSDETLDKVPKSEGYCSRILRVQGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKVCEQDSTFDGVTDRPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC", "length": 807, "header": "tr|A0A4X1TLK4-1|A0A4X1TLK4_PIG Isoform 1 of Spondin-1 OS=Sus scrofa OX=9823 GN=SPON1 PE=1 SV=1 CANONICAL=A0A4X1TLK4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TLB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4/entry#A0A4X1TLB3-1", "sequence": { "sequence": "MRLSPASVKLSGSPALLALALPLAAALAFSDETLDKVPKSEGYCSRILRVQGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKVCEQDSTFDGVTDRPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECYTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC", "length": 751, "header": "tr|A0A4X1TLB3-1|A0A4X1TLK4_PIG Computationally mapped isoform of Spondin-1 OS=Sus scrofa OX=9823 GN=SPON1 PE=1 SV=1 CANONICAL=A0A4X1TLK4-1" }, "locus": { "chromosome": "2", "start_pos": 45299249, "end_pos": 44970560, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052672.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052672.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043017.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043017.1" } ] } }, { "isoform_ac": "A0A4X1TLK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4/entry#A0A4X1TLK4-1", "sequence": { "sequence": "MRLSPASVKLSGSPALLALALPLAAALAFSDETLDKVPKSEGYCSRILRVQGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKVCEQDSTFDGVTDRPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC", "length": 807, "header": "tr|A0A4X1TLK4-1|A0A4X1TLK4_PIG Isoform 1 of Spondin-1 OS=Sus scrofa OX=9823 GN=SPON1 PE=1 SV=1 CANONICAL=A0A4X1TLK4-1" }, "locus": { "chromosome": "2", "start_pos": 45299249, "end_pos": 44970560, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014630.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014630.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014235.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014235.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLB3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLB3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516954", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516954", "resource": "KEGG Pathway" }, { "id": "R-SSC-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZXW0-1", "protein_name": "Spondin-1", "gene_name": "SPON1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAARLRPLALRLLALTFPLVARGFSDETLEKAAKSEGYCSRILRAQGTRREGYNEFSLRVEGDPEFYKPGNSYRVTLSAATPAYFRGFTLIALKEGKEGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWTAPPTGTGCVILKASIVQKRIIYFQDEGSLTKRICEQDSASEGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDFPRRTNHWSAIIGSSHSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQKVVQDLIPWDAGTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGSIKLVARVVIERIARKGEQCNIVPDNIDDIVADLAPEEKEEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCMMSDWITWSPCSVSCGMGTRSRERYVKQFPEDGSMCKVPTEETEKCIVNEECSPSSCLVTEWGEWDECSASCGTGMKRRHRMIKMTPADGSMCKAETTEAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSAAELGDCNEELEQAEKCMLPECPIDCELTEWSQWSECNTSCGKGHMIRTRMIKIEPQFGGTACPETVQRTKCRVRKCLRGPGMEKRRWKEAREKRRSEQAKKNIDNEQYPVCRLKPWTAWTECSTLCGGGIQERYMMVKKRSKSTQFTSCKDKKELRACNVHPC", "length": 802 }, "evidence": [ { "id": "A0A4X1TLK4", "url": "https://omabrowser.org/oma/group/A0A4X1TLK4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P35446-1", "protein_name": "Spondin-1", "gene_name": "Spon1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLSPAPLRLSRGPALLALALPLAAALAFSDETLDKVAKSEGYCSRILRAQGTRREGYTEFSLRVEGDPDFYKPGSSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPTGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDPTLDGVTDRPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPSWQPVNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSVSCGMGMRSRERYVKQFPEDGSVCMLPTEETEKCTVNEECSPSSCLVTEWGEWDDCSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQAEKCMLPECPIDCELSEWSQWSECNKSCGKGHMIRTRTIQMEPQFGGAPCPETVQRKKCRARKCLRSPSIQKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC", "length": 807 }, "evidence": [ { "id": "A0A4X1TLK4", "url": "https://omabrowser.org/oma/group/A0A4X1TLK4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VCC9-1", "protein_name": "Spondin-1", "gene_name": "Spon1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLSPVSLRLSRGPALLALALPLAAALAFSDETLDKVTKSEGYCSRILRAQGTRREGYTEFSLRVEGDPDFYKPGSSYRVTLSAAPPSYFRGFTLIALKENQEGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPTGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDPTLDGVTDRPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPVNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSVSCGMGMRSRERYVKQFPEDGSVCMLPTEETEKCTVNEECSPSSCLVTEWGEWDDCSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQAEKCMLPECPIDCELSEWSQWSECNKSCGKGHMIRTRTIQMEPQFGGVPCPETVQRKKCRTRKCLRSPSVQKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC", "length": 807 }, "evidence": [ { "id": "A0A4X1TLK4", "url": "https://omabrowser.org/oma/group/A0A4X1TLK4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GLX9-1", "protein_name": "Spondin-1", "gene_name": "SPON1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLSPVLLRLSRGPALLALALPLAVALAFSDETLDKVPKSEGYCSRILRVQGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGTGTRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC", "length": 807 }, "evidence": [ { "id": "A0A4X1TLK4", "url": "https://omabrowser.org/oma/group/A0A4X1TLK4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9HCB6-1", "protein_name": "Spondin-1", "gene_name": "SPON1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLSPAPLKLSRTPALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALRENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMIKMNPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC", "length": 807 }, "evidence": [ { "id": "A0A4X1TLK4", "url": "https://omabrowser.org/oma/group/A0A4X1TLK4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLK4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLK4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4" } ], "pmid": "" }, { "name": "LBD domain binding", "id": "GO:0050693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050693", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLK4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLK4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TLK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4" }, { "id": "PS51019", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51019" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reelin", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 194, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TLK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLK4" }, { "id": "PS51020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Spondin", "eco_id": "ECO_0000259", "start_pos": 195, "end_pos": 388, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 681, "end_pos": 683 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TLJ5-1", "uniprot_ac": "A0A4X1TLJ5", "uniprot_id": "A0A4X1TLJ5_PIG", "mass": { "chemical_mass": 72009.0, "monoisotopic_mass": 72009.0 }, "refseq": {}, "gene_names": [ { "name": "KIFBP", "type": "recommended", "evidence": [ { "id": "A0A4X1TLJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5" } ] } ], "protein_names": [ { "name": "KIF-binding protein", "type": "recommended", "evidence": [ { "id": "A0A4X1TLJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5/entry#names_and_taxonomy" } ] }, { "name": "KIF1-binding protein", "type": "synonym", "evidence": [ { "id": "A0A4X1TLJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Activator of KIF1B plus-end-directed microtubule motor activity. Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5#function" }, { "database": "UniProtKB", "id": "ARBA00045179", "url": "https://www.uniprot.org/uniprotkb/ARBA00045179#function" }, { "database": "UniProtKB", "id": "A0A8W4FDM9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDM9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KIFBP", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5", "locus": { "chromosome": "14", "start_pos": 72099211, "end_pos": 72069395, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010248", "url": "https://www.ensembl.org/id/ENSSSCG00000010248" } ] } } ], "crossref": [ { "id": "A0A4X1TLJ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TLJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010248", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010248", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100151916", "url": "https://www.ncbi.nlm.nih.gov/gene/100151916", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100151916", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151916", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICRECWY", "url": "https://omabrowser.org/oma/group/ICRECWY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TLJ5", "url": "https://www.orthodb.org/?gene=A0A4X1TLJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46321", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46321", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46321:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46321:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12309", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12309", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1TLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q8X9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q8X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q8X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q8X9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1I7W9", "url": "https://www.uniprot.org/uniprotkb/A0A8D1I7W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1I7W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1I7W9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDM9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADAPWVELREKFQAALALSRVELHKNPEKEPYKSKYHARALLEEVKALLGPAPEDEDDRPQAEDSLGTGDHTLGLPAELVEAEGPIALGAVRRAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRKYRMSQDCVSLYIQAQNNLGILWSEREEIESAQAYLESSEALYNQYMKEIGSPPLDPTEHFLSEEEKLAEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKQCFMEARHCLSAANVIFGQTGKISTMEDTTEAEGDVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESVRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLTGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLIVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADKLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCERHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT", "length": 621, "header": "tr|A0A4X1TLJ5-1|A0A4X1TLJ5_PIG Isoform 1 of KIF-binding protein OS=Sus scrofa OX=9823 GN=KIFBP PE=1 SV=1 CANONICAL=A0A4X1TLJ5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TLJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5/entry#A0A4X1TLJ5-1", "sequence": { "sequence": "MADAPWVELREKFQAALALSRVELHKNPEKEPYKSKYHARALLEEVKALLGPAPEDEDDRPQAEDSLGTGDHTLGLPAELVEAEGPIALGAVRRAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRKYRMSQDCVSLYIQAQNNLGILWSEREEIESAQAYLESSEALYNQYMKEIGSPPLDPTEHFLSEEEKLAEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKQCFMEARHCLSAANVIFGQTGKISTMEDTTEAEGDVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESVRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLTGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLIVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADKLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCERHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT", "length": 621, "header": "tr|A0A4X1TLJ5-1|A0A4X1TLJ5_PIG Isoform 1 of KIF-binding protein OS=Sus scrofa OX=9823 GN=KIFBP PE=1 SV=1 CANONICAL=A0A4X1TLJ5-1" }, "locus": { "chromosome": "14", "start_pos": 72098669, "end_pos": 72071988, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011218.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011218.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010926.2", "url": "https://www.ensembl.org/id/ENSSSCP00000010926.2" } ] } }, { "isoform_ac": "A0A5G2Q8X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5/entry#A0A5G2Q8X9-1", "sequence": { "sequence": "MADAPWVELREKFQAALALSRVELHKNPEKEPYKSKYHARALLEEVKALLGPAPEDEDDRPQAEDSLGTGDHTLGLPAELVEAEGPIALGAVRRAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRKYRMSQDCVSLYIQAQNNLGILWSEREEIESAQAYLESSEALYNQYMKEIGSPPLDPTEHFLSEEEKLAEQERSKRTT", "length": 204, "header": "tr|A0A5G2Q8X9-1|A0A4X1TLJ5_PIG Computationally mapped isoform of KIF-binding protein OS=Sus scrofa OX=9823 GN=KIFBP PE=1 SV=2 CANONICAL=A0A4X1TLJ5-1" }, "locus": { "chromosome": "14", "start_pos": 72097803, "end_pos": 72071988, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091317.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091317.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060371.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060371.2" } ] } }, { "isoform_ac": "A0A8D1I7W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5/entry#A0A8D1I7W9-1", "sequence": { "sequence": "MADAPWVELREKFQAALALSRVELHKNPEKEPYKSKYHARALLEEVKALLGPAPEDEDDRPQAEDSLGTGDHTLGLPAELVEAEGPIALGAVRRAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRKYRMSQDCVSLYIQAQIGSPPLDPTEHFLSEEEKLAEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKQCFMEARHCLSAANVIFGQTGKISTMEDTTEAEGDVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESVRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLTGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLIVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADKLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCERHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT", "length": 588, "header": "tr|A0A8D1I7W9-1|A0A4X1TLJ5_PIG Computationally mapped isoform of KIF-binding protein OS=Sus scrofa OX=9823 GN=KIFBP PE=1 SV=1 CANONICAL=A0A4X1TLJ5-1" }, "locus": { "chromosome": "14", "start_pos": 72098669, "end_pos": 72071988, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095040.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095040.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076418.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076418.1" } ] } }, { "isoform_ac": "A0A8W4FDM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5/entry#A0A8W4FDM9-1", "sequence": { "sequence": "MADAPWVELREKFQAALALSRVELHKNPEKEPYKSKYHARALLEEVKALLGPAPEDEDDRPQAEDSLGTGDHTLGLPAELVEAEGPIALGAVRRAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRKYRMSQDCVSLYIQAQNNLGILWSEREEIESAQAYLESSEALYNQYMKEIGSPPLDPTEHFLSEEEKLAEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKQCFMEARHCLSAANVIFGQTGKISTMEDRQHRRA", "length": 297, "header": "tr|A0A8W4FDM9-1|A0A4X1TLJ5_PIG Computationally mapped isoform of KIF-binding protein OS=Sus scrofa OX=9823 GN=KIFBP PE=1 SV=1 CANONICAL=A0A4X1TLJ5-1" }, "locus": { "chromosome": "14", "start_pos": 72097813, "end_pos": 72071988, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102002.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102002.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077521.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077521.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2Q8X9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q8X9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100151916", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151916", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3SYS9-1", "protein_name": "KIF-binding protein", "gene_name": "KIFBP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADSPWDEIREKFQTALALSRVELHKNPEKEPYKSKYSARALLEEVKALLGPAPEDEDERPQADDSLGAGEHALGLPAELVEAEGPVAQGAVRRAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRKYRLSHDCVSLYIQAQNNLGILWSEREEIETAQAYLESSEALYNQYMKEIGSPPLDPTEHFLPEEEKLPEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKQCFMEARHCLSAANVIFGQIGKIRTTEDTTEAEGDVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESVRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLTGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLIVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADKLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCEKHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT", "length": 621 }, "evidence": [ { "id": "A0A4X1TLJ5", "url": "https://omabrowser.org/oma/group/A0A4X1TLJ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4G074-1", "protein_name": "KIF-binding protein", "gene_name": "Kifbp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGAPGPEIREKFQAALALSRVELHKNPEKEPYKSKYGARALLEEVRALLGPAPEDDDERAADDGPVDQALGAGEPRDAEGPGAQRALRLAVVEFHLGVNHIDTEELSAGEEHLVRCLSLLRPYRLSLGCVSLFIQAQNNLGILWSEREEIETARTYLESSEALYNQYMKEIGSPPLDPTEHFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKITATEDTPEVEGDMPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRRKELDEEESVRKRAVQFGTGELRDAISAVEEKVRYLRPLDFEEARELFLLGQHYVYEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFEADMERRCKMHKRRIAMLEPLIVDLNPQYYQLVNRQIQFEIAHAYYDMMDLKVAIADKLREPDSHTVKKINSLNQSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCETHPEAAQEIEVELELSKEMVSLLPTKMERFRAKMALT", "length": 617 }, "evidence": [ { "id": "A0A4X1TLJ5", "url": "https://omabrowser.org/oma/group/A0A4X1TLJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5ZIL9-1", "protein_name": "KIF-binding protein", "gene_name": "Kifbp", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAGGGWAAACEKFRSARTLSAVESRKDPETEPYRSKYSARALLQEVKQQLSAAEDCGEARLLAVRRAVLEYELGVNHTDTEELSAGEEHLQRCTQLLEPHRLSRDCVSLYIQAQNNLGILWSERDEIKTAQTYLESAEALYNQYMKEDGNPPLDPSEHFMAEEEKLTDQERSKRFEKAYTHTLYYLAQVYQHLEMIEKAAQYCHTTLKRQLEYCGYYPVEWALNAATLSQYYLSKQCFMESRHCLAAASVIFSQAGQVPSTEDNETEQDQQDLRQRKAEIARCWIKYCLNLLQSARKLLEDNIGELDPDRQLELKAQRKKEEDEKENGRKKAVLFGTSDICDSVLAMEEKVSSVYPLDFQEAREIFLVGQNYVQEAKEFFQVDGYVTDHIEIVQDHSALFKVLAFFEEDYERRCKMHKRRIDMLEPIYADLNPQYYLLISRQLQFELADTYYEMMDLKVAIGNRLEELDSHTIKKINSLAQLAIKYYELFLDSLRNPDKVFPEELEEDVLRPAMVAKFHIARLYGKLITSDSKKQLENMQTSLEYYTFLVDYCEKHPDAVRAVETELELSKEMVGLLPTRMERLRAKLCPFI", "length": 594 }, "evidence": [ { "id": "A0A4X1TLJ5", "url": "https://omabrowser.org/oma/group/A0A4X1TLJ5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6ZPU9-1", "protein_name": "KIF-binding protein", "gene_name": "Kifbp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANAPGPEIREKFQAALALSRVELHKNPEKEPYKSKYGARALLEEVRALLGPAPEDEDEPAADDGPGDQALGAGEPREAEGPGAQRALRLAVVEFHLGVNHIDTEELSAGEEHLVRCLSLLRPYRLSLGCVSLYIQAQNNLGILWSEREEIETARTYLESSEALYSQYMKEIGSPPLDPTEHFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKIPATEDTPEVEGDVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESVRKRAVQFGTGELCDAISAVEEKVRYLRPLDFEEARELFLLGQHYVCEAKEFFQIDGYVTDHIEVVQDHSALFKVLSFFEADMERRCKMHKRRIAMLEPLTVDLNPQYYLLVSRQIQFEIAHAYYDMMDLKVAIADKLRDPDSHIVKKINSLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCETHPEAAQEIEVELELSKEMVSLLPTKMERFRAKMALT", "length": 617 }, "evidence": [ { "id": "A0A4X1TLJ5", "url": "https://omabrowser.org/oma/group/A0A4X1TLJ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96EK5-1", "protein_name": "KIF-binding protein", "gene_name": "KIFBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANVPWAEVCEKFQAALALSRVELHKNPEKEPYKSKYSARALLEEVKALLGPAPEDEDERPEAEDGPGAGDHALGLPAEVVEPEGPVAQRAVRLAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRRYRLSHDCISLCIQAQNNLGILWSEREEIETAQAYLESSEALYNQYMKEVGSPPLDPTERFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHLEMFEKAAHYCHSTLKRQLEHNAYHPIEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKISATEDTPEAEGEVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESIRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLLGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLTVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADRLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCEKHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT", "length": 621 }, "evidence": [ { "id": "A0A4X1TLJ5", "url": "https://omabrowser.org/oma/group/A0A4X1TLJ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VMX1-1", "protein_name": "KIF-binding protein", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVIPKEILSDFKELYEKANRLVEEESRNDPPTDPFRSHYKARDVLIVLKKQLDDQLVSVQASEEDGGQDDRCYHSLLAFVCRDLGRIYIYTEEQAEGEKMLNRCLELVTPFKECPEGIIPFIGAINELSIVLASKEEYNKGLEILLEAEKIYEDFKASGLKPLAIQDVFNPPEEGQQSHEAGPKELESLYTLVSFYMAQMYGHLGEPEKSAKCCHRTLHRQLESKTYDPIDFALNTATLSQFYIGEKRFEEARHHLAAATLIMAEYEVHMLEPEMSEKQRQDVSETFKHRYADVARCWAKYGLYLMNTSKLRLMRDEDDEDAKNLEIVLRNMRLVEAEQSRFPGLDLTACENRISCEYCLTFDDAKLVFHFVNEWLDIAKDYYKAENEATEYSKIMQDYAEAYEHIAFFEENPENQAKMQKRRAKYLEDLLDLLDPIFYMKICRECWYGAGTAHAAVMDVRLDIIRATSTPAPEDIKKVNQSCMKAIKHFESYVKSYLVKPPSEEWRPNMDVEEQRHMLYAHFHIGRIYYKLISGHPLQQLEHLTSCHTYYQRFDAGCQLHKEAAETLQGEIGVVREMLQLLPLKINTIKARLNKAGLTA", "length": 600 }, "evidence": [ { "id": "A0A4X1TLJ5", "url": "https://omabrowser.org/oma/group/A0A4X1TLJ5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mitochondrion transport along microtubule", "id": "GO:0047497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047497", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5" } ], "pmid": "" }, { "name": "neuron projection maintenance", "id": "GO:1990535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990535", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5" } ], "pmid": "" }, { "name": "central nervous system projection neuron axonogenesis", "id": "GO:0021952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021952", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 510, "end_pos": 512 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TLL5-1", "uniprot_ac": "A0A4X1TLL5", "uniprot_id": "A0A4X1TLL5_PIG", "mass": { "chemical_mass": 107645.0, "monoisotopic_mass": 107645.0 }, "refseq": { "ac": "XP_005667701", "name": "PHD finger protein 14 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667701" }, "gene_names": [ { "name": "PHF14", "type": "recommended", "evidence": [ { "id": "A0A4X1TLL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5" } ] }, { "name": "PHF14", "type": "synonym", "evidence": [ { "id": "XP_005667701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667701" } ] } ], "protein_names": [ { "name": "PHD finger protein 14", "type": "recommended", "evidence": [ { "id": "A0A4X1TLL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5/entry#names_and_taxonomy" } ] }, { "name": "PHD finger protein 14 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005667701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667701" } ] } ], "function": [ { "annotation": "Histone-binding protein. Binds preferentially to unmodified histone H3 but can also bind to a lesser extent to histone H3 trimethylated at 'Lys-9' (H3K9me3) as well as to histone H3 monomethylated at 'Lys-27' (H3K27ac) and trimethylated at 'Lys-27' (H3K27me3). Represses PDGFRA expression, thus playing a role in regulation of mesenchymal cell proliferation. Suppresses the expression of CDKN1A/p21 by reducing the level of trimethylation of histone H3 'Lys-4', leading to enhanced proliferation of germinal center B cells.", "evidence": [ { "database": "UniProtKB", "id": "I3L5I3", "url": "https://www.uniprot.org/uniprotkb/I3L5I3#function" }, { "database": "UniProtKB", "id": "ARBA00058058", "url": "https://www.uniprot.org/uniprotkb/ARBA00058058#function" }, { "database": "UniProtKB", "id": "A0A4X1TLL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PHF14", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5", "locus": { "chromosome": "9", "start_pos": 80866146, "end_pos": 80678207, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026722", "url": "https://www.ensembl.org/id/ENSSSCG00000026722" } ] } } ], "crossref": [ { "id": "A0A4X1TLL5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TLL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026722", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026722", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15561", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15561", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15562", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15562", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15563", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15563", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512066", "url": "https://www.ncbi.nlm.nih.gov/gene/100512066", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KCGVAVH", "url": "https://omabrowser.org/oma/group/KCGVAVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TLL5", "url": "https://www.orthodb.org/?gene=A0A4X1TLL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13793:SF150", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13793:SF150", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13831", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005667701", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667701", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TLL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLM4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L5I3", "url": "https://www.uniprot.org/uniprotkb/I3L5I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L5I3-1", "url": "https://www.uniprot.org/uniprotkb/I3L5I3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDPSKDSGEGSCSDSEENILEEELNEDIKVKEEQLKNSAEEEILSSEKQLIKVEKKEEEENGERPRKKKEKEKEKEKEKEKEKEKDKEKEREKDKEKATVSDNVAASAASTTPATSPPGVNTSPSVPTTATTEEQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDEDEGSGSDEDENDEGNDEDHSSPASEGGCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQLSPEAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITGQKLNIPAILRAPKERKPSKKEGGTQKTSTLPAVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSDMEADMAMETLPDGTKRSRRQIKEPVKFVPQDMPPEPKKIPIRNTRTRGRKRSFIPEEEKHEERVPRERRQRQSVLQKKPKAEDLRTECATCKGTGDNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDSSSSKEDENEAERKNISQELCMELKNPKK", "length": 953, "header": "tr|A0A4X1TLL5-1|A0A4X1TLL5_PIG Isoform 1 of PHD finger protein 14 OS=Sus scrofa OX=9823 GN=PHF14 PE=4 SV=1 CANONICAL=A0A4X1TLL5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TLL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5/entry#A0A4X1TLL5-1", "sequence": { "sequence": "MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDPSKDSGEGSCSDSEENILEEELNEDIKVKEEQLKNSAEEEILSSEKQLIKVEKKEEEENGERPRKKKEKEKEKEKEKEKEKEKDKEKEREKDKEKATVSDNVAASAASTTPATSPPGVNTSPSVPTTATTEEQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDEDEGSGSDEDENDEGNDEDHSSPASEGGCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQLSPEAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITGQKLNIPAILRAPKERKPSKKEGGTQKTSTLPAVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSDMEADMAMETLPDGTKRSRRQIKEPVKFVPQDMPPEPKKIPIRNTRTRGRKRSFIPEEEKHEERVPRERRQRQSVLQKKPKAEDLRTECATCKGTGDNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDSSSSKEDENEAERKNISQELCMELKNPKK", "length": 953, "header": "tr|A0A4X1TLL5-1|A0A4X1TLL5_PIG Isoform 1 of PHD finger protein 14 OS=Sus scrofa OX=9823 GN=PHF14 PE=4 SV=1 CANONICAL=A0A4X1TLL5-1" }, "locus": { "chromosome": "9", "start_pos": 80866023, "end_pos": 80678360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031171.3", "url": "https://www.ensembl.org/id/ENSSSCT00000031171.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021971.2", "url": "https://www.ensembl.org/id/ENSSSCP00000021971.2" } ] } }, { "isoform_ac": "A0A4X1TLM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5/entry#A0A4X1TLM4-1", "sequence": { "sequence": "MIVQMTVILKLEMLQDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQLSPEAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITGQKLNIPAILRAPKERKPSKKEGGTQKTSTLPAVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSDMEADMAMETLPDGTKRSRRQIKEPVKFVPQDMPPEPKKIPIRNTRTRGRKRSFIPEEEKHEERVPRERRQRQSVLQKKPKAEDLRTECATCKGTGDNENLVRYPS", "length": 603, "header": "tr|A0A4X1TLM4-1|A0A4X1TLM4_PIG Computationally mapped isoform of PHD finger protein 14 OS=Sus scrofa OX=9823 GN=PHF14 PE=4 SV=1 CANONICAL=A0A4X1TLL5-1" }, "locus": { "chromosome": "9", "start_pos": 80801376, "end_pos": 80678928, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047756.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047756.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045073.1", "url": "https://www.ensembl.org/id/ENSSSCP00000045073.1" } ] } }, { "isoform_ac": "I3L5I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5/entry#I3L5I3-1", "sequence": { "sequence": "MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDPSKDSGEGSCSDSEENILEEELNEDIKVKEEQLKNSAEEEILSSEKQLIKVEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKDKEKATVSDNVAASAASTTPATSPPGVNTSPSVPTTATTEEQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDEDEGSGSDEDENDEGNDEDHSSPASEGGCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQLSPEAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITGQKLNIPAILRAPKERKPSKKEGGTQKTSTLPAVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSDMEADMAMETLPDGTKRSRRQIKEPVKFVPQDMPPEPKKIPIRNTRTRGRKRSFIPEEEKHEERVPRERRQRQSVLQKKPKAEDLRTECATCKGTGDNENLVRYPS", "length": 887, "header": "tr|I3L5I3-1|A0A4X1TLL5_PIG Computationally mapped isoform of PHD finger protein 14 OS=Sus scrofa OX=9823 GN=PHF14 PE=4 SV=4 CANONICAL=A0A4X1TLL5-1" }, "locus": { "chromosome": "9", "start_pos": 80801376, "end_pos": 80678360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032105.4", "url": "https://www.ensembl.org/id/ENSSSCT00000032105.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019282.4", "url": "https://www.ensembl.org/id/ENSSSCP00000019282.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3L5I3", "url": "https://www.uniprot.org/uniprotkb/I3L5I3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K7P2-1", "protein_name": "PHD finger protein 14", "gene_name": "Phf14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDPSKDSGEGSCSDSEENILEEELNEDIKVKEEQLRNSTEEIMSSDKQLIKMEKKEEEENGERPRKRKEKEKEKEKEREKDKEKATVSDSAAASAAGTTPATSPPAVTSPAVPTTTTSSEEQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDDDEGSGSEEDENDEGNDEDHSSPASEAGGKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQLSPEAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITGQKLNVPAILRAPKERKPSKKEGGTQKTSSLPTVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSDMEAEMAMETLPDGTKRSRRQIKEPVKFVPQDVPPEPKKIPIRNTRTRGRKRSFVPEEEKHEERVPRERRQRQSVLQKKPKAEDLRTECSTCKGTGENENLVSRMRLSEAKNRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDSSSSKEDENEAGKKNASQELSMEQKNPKK", "length": 950 }, "evidence": [ { "id": "A0A4X1TLL5", "url": "https://omabrowser.org/oma/group/A0A4X1TLL5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A286Y9D1-1", "protein_name": "PHD finger protein 14", "gene_name": "phf14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDRGSKRRQVKPLADSLLDALDYDSSDDSDFKVGESSGSEGTGNGSDEEGSKESAAGSESDSDAAAASADEEGIDDLETKDLNQEDDEEEKVKESFSEETSSKETGGSSRSRKKGEKSSDMEPNGSATTEENSAEPKKWNLRRNRPMLDFTTMEELNEMDDYDSEDDNDWRPTQGKKKGKASSGKEKEGSGEEDDDDDDGGSDEEDNEDDNDDDDDDDDEGNDDESSSSDSEEEGKKPKKKAGKNTGAFDEEETNDSHSTSHGKGNEDSLLERPQTWSSQRMEHILICCVCLGDNSEDADEIIQCDNCGVTVHEGCYGVDGESDSIMSSASENSTEPWFCDACKNGVSPSCELCPSQDGIFKETDAGRWVHVVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSLCEDTRFARTGVCISCDAGMCRSFFHVTCAQREGLLSEAAAEEDIADPFFAYCKQHADRFDRKWKRKNYLALQSYCKVSLQEREKQLTPEAQARITTRLQQYRAKAELSRNTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDTSDISASVDGRRKHKQPALTADFVNYYLERNMRMIQIQDNIVEQKNLKDKLESEQEKLHMEYDKLCESLEDLQNVNGQLRTEGQSIWSMMGGIVGQKLNVPAVLKAPKERKPSKKEGGSPGKSSSLPAMLYSCGICKKNQDQHLLLLCDTCKLHYHLGCLDPPLTRMPKKTKNSYWQCSECDQASSDEADIAMETLPDGTKRSRRQIKGPIKFIPQEMSPEPKKPQVRGTRTRGQKRKRMSICEEEKMEEPLPRERRQRQSTLQKKPKADDTRTECTTCKGPGDNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDTSSSKEEEAQEVEEESVNEETAEQEIPD", "length": 914 }, "evidence": [ { "id": "A0A4X1TLL5", "url": "https://omabrowser.org/oma/group/A0A4X1TLL5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O94880-3", "protein_name": "PHD finger protein 14", "gene_name": "PHF14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDASKDSGEGSCSDSEENILEEELNEDIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEEQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDEDEGSGSDEDENDEGNDEDHSSPASEGGCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQLSPEAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITGQKLNIPAILRAPKERKPSKKEGGTQKTSTLPAVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSDMEADMAMETLPDGTKRSRRQIKEPVKFVPQDVPPEPKKIPIRNTRTRGRKRSFVPEEEKHEERVPRERRQRQSVLQKKPKAEDLRTECATCKGTGDNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDSSSSKEDENEAERKNISQELNMEQKNPKK", "length": 948 }, "evidence": [ { "id": "A0A4X1TLL5", "url": "https://omabrowser.org/oma/group/A0A4X1TLL5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D4H9-2", "protein_name": "PHD finger protein 14", "gene_name": "Phf14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDPSKDSGEGSCSDSEENILEEELNEDIQVKEEQLKNSTEEIMPSDKQLIKMEKKEEEENGERPRKKKEKEKEKEKEREKDKEKATVSDSAAASAAGTTPATSPPAVTSPSVPTTTTTTTEEQVSEPKKWNLRRNRPLLDFVSMEELNAMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDDDEGSGSEEDENDEGNDEDHSSPASEAGGKKKRSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQLSPEAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITGQKLNVPAILRAPKERKPSKKEGGTQKTSALPTVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSDMEAEMAMETLPDGTKRSRRQIKEPVKFVPQDVPPEPKKIPIRNTRTRGRKRSFVPEEEKHEERVPRERRQRQSVLQKKPKAEDLRTECSTCKGTGDNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDSSSSKEDENEAEKKNASQELSMEQKTPKK", "length": 941 }, "evidence": [ { "id": "A0A4X1TLL5", "url": "https://omabrowser.org/oma/group/A0A4X1TLL5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5" } ], "pmid": "" }, { "name": "germinal center B cell differentiation", "id": "GO:0002314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002314", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5" } ], "pmid": "" }, { "name": "histone reader activity", "id": "GO:0140566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140566", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 939, "end_pos": 941, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TLL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLL5" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" }, { "id": "PS51805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 324, "end_pos": 385, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 315, "end_pos": 317 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 437, "end_pos": 439 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 939, "end_pos": 941 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TLP9-1", "uniprot_ac": "A0A4X1TLP9", "uniprot_id": "A0A4X1TLP9_PIG", "mass": { "chemical_mass": 7492.0, "monoisotopic_mass": 7492.0 }, "refseq": { "ac": "XP_003125332", "name": "39S ribosomal protein L33, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125332" }, "gene_names": [ { "name": "MRPL33", "type": "recommended", "evidence": [ { "id": "A0A4X1TLP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9" } ] }, { "name": "MRPL33", "type": "synonym", "evidence": [ { "id": "XP_003125332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125332" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein bL33m", "type": "recommended", "evidence": [ { "id": "A0A4X1TLP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L33, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003125332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125332" }, { "id": "A0A4X1TLP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLP9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MRPL33", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9", "locus": { "chromosome": "3", "start_pos": 111428856, "end_pos": 111438707, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034129", "url": "https://www.ensembl.org/id/ENSSSCG00000034129" } ] } } ], "crossref": [ { "id": "A0A4X1TLP9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TLP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100520487", "url": "https://www.ncbi.nlm.nih.gov/gene/100520487", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "6GAW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6GAW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6GB2", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6GB2&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6YDP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6YDP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6YDW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6YDW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NQH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NQH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NQL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NQL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NSH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NSH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NSI", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NSI&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NSJ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NSJ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8OIN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OIN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8OIQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OIQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520487", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520487", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TCFNVKR", "url": "https://omabrowser.org/oma/group/TCFNVKR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TLP9", "url": "https://www.orthodb.org/?gene=A0A4X1TLP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47037:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47037:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00006gaw", "url": "https://www.rcsb.org/structure/pdb_00006gaw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006gb2", "url": "https://www.rcsb.org/structure/pdb_00006gb2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006ydp", "url": "https://www.rcsb.org/structure/pdb_00006ydp", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006ydw", "url": "https://www.rcsb.org/structure/pdb_00006ydw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nqh", "url": "https://www.rcsb.org/structure/pdb_00007nqh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nql", "url": "https://www.rcsb.org/structure/pdb_00007nql", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nsh", "url": "https://www.rcsb.org/structure/pdb_00007nsh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nsi", "url": "https://www.rcsb.org/structure/pdb_00007nsi", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nsj", "url": "https://www.rcsb.org/structure/pdb_00007nsj", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008oin", "url": "https://www.rcsb.org/structure/pdb_00008oin", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008oiq", "url": "https://www.rcsb.org/structure/pdb_00008oiq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6GAW", "url": "https://www.rcsb.org/structure/6GAW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6GB2", "url": "https://www.rcsb.org/structure/6GB2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6YDP", "url": "https://www.rcsb.org/structure/6YDP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6YDW", "url": "https://www.rcsb.org/structure/6YDW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NQH", "url": "https://www.rcsb.org/structure/7NQH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NQL", "url": "https://www.rcsb.org/structure/7NQL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NSH", "url": "https://www.rcsb.org/structure/7NSH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NSI", "url": "https://www.rcsb.org/structure/7NSI", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NSJ", "url": "https://www.rcsb.org/structure/7NSJ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OIN", "url": "https://www.rcsb.org/structure/8OIN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OIQ", "url": "https://www.rcsb.org/structure/8OIQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00471", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00471", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003125332", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125332", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TLP9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLSAVTFAKSKSKTILVKMMSQAGTGFSFNTKRSRLREKLTLLHYDPVVKKKVLFVEQKKIRSL", "length": 65, "header": "tr|A0A4X1TLP9-1|A0A4X1TLP9_PIG Isoform 1 of Large ribosomal subunit protein bL33m OS=Sus scrofa OX=9823 GN=MRPL33 PE=1 SV=1 CANONICAL=A0A4X1TLP9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TLP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9/entry#A0A4X1TLP9-1", "sequence": { "sequence": "MFLSAVTFAKSKSKTILVKMMSQAGTGFSFNTKRSRLREKLTLLHYDPVVKKKVLFVEQKKIRSL", "length": 65, "header": "tr|A0A4X1TLP9-1|A0A4X1TLP9_PIG Isoform 1 of Large ribosomal subunit protein bL33m OS=Sus scrofa OX=9823 GN=MRPL33 PE=1 SV=1 CANONICAL=A0A4X1TLP9-1" }, "locus": { "chromosome": "3", "start_pos": 111438628, "end_pos": 111429108, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042508.1", "url": "https://www.ensembl.org/id/ENSSSCT00000042508.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034999.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034999.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.", "journal": "Nature", "date": "2018", "authors": "Kummer Eva, Leibundgut Marc, Rackham Oliver, Lee Richard G, Boehringer Daniel, Filipovska Aleksandra, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLP9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9" } ], "reference": [ { "type": "PubMed", "id": "30089917", "url": "https://glygen.org/publication/PubMed/30089917" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLP9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Structural insights into mammalian mitochondrial translation elongation catalyzed by mtEFG1.", "journal": "EMBO J.", "date": "2020", "authors": "Kummer E, Ban N", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLP9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9" } ], "reference": [ { "type": "PubMed", "id": "32602580", "url": "https://glygen.org/publication/PubMed/32602580" } ] }, { "title": "Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.", "journal": "Mol. Cell", "date": "2021", "authors": "Kummer Eva, Schubert Katharina Noel, Schoenhut Tanja, Scaiola Alain, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLP9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9" } ], "reference": [ { "type": "PubMed", "id": "33878294", "url": "https://glygen.org/publication/PubMed/33878294" } ] }, { "title": "Molecular basis of translation termination at noncanonical stop codons in human mitochondria.", "journal": "Science", "date": "2023", "authors": "Saurer Martin, Leibundgut Marc, Nadimpalli Hima Priyanka, Scaiola Alain, Sch\u00f6nhut Tanja, Lee Richard G, Siira Stefan J, Rackham Oliver, Dreos Ren\u00e9, Lenar\u010di\u010d Tea, Kummer Eva, Gatfield David, Filipovska Aleksandra, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLP9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9" } ], "reference": [ { "type": "PubMed", "id": "37141370", "url": "https://glygen.org/publication/PubMed/37141370" } ] } ], "pathway": [ { "id": "ssc:100520487", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520487", "resource": "KEGG Pathway" }, { "id": "R-SSC-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-SSC-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-SSC-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2L677-1", "protein_name": "Large ribosomal subunit protein bL33m", "gene_name": "mrpl33", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFLTTVNLAKSKSKTLLVQMVSAAGTGYSFNTKRGRLREKLVLRKNDPIVNKHVLFFEKKKVRSL", "length": 65 }, "evidence": [ { "id": "A0A4X1TLP9", "url": "https://omabrowser.org/oma/group/A0A4X1TLP9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8C2N140-1", "protein_name": "Large ribosomal subunit protein bL33m", "gene_name": "Mrpl33", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLLSAVSFAKSKSKTILVRLVSQAGTGFSFNHKRSRLREKLTLLHYDPIVNKKVLFVEQKKIRSL", "length": 65 }, "evidence": [ { "id": "A0A4X1TLP9", "url": "https://omabrowser.org/oma/group/A0A4X1TLP9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4ABL7-1", "protein_name": "Large ribosomal subunit protein bL33m", "gene_name": "Mrpl33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLSAVSFAKSKSKTILVKLVSQAGTGFSFNYKRSRLREKLTLLHYDPIVNKKVLFVEQKKIRSL", "length": 65 }, "evidence": [ { "id": "A0A4X1TLP9", "url": "https://omabrowser.org/oma/group/A0A4X1TLP9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75394-1", "protein_name": "Large ribosomal subunit protein bL33m", "gene_name": "MRPL33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLSAVFFAKSKSKNILVRMVSEAGTGFCFNTKRNRLREKLTLLHYDPVVKQRVLFVEKKKIRSL", "length": 65 }, "evidence": [ { "id": "A0A4X1TLP9", "url": "https://omabrowser.org/oma/group/A0A4X1TLP9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3SZ47-1", "protein_name": "Large ribosomal subunit protein bL33m", "gene_name": "MRPL33", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFLSAVTFAKSKSKTILVKMVSQAGTGFSFNTKRSRLWEKLTLLHYDPVVKKKVLFVEQKKIRSL", "length": 65 }, "evidence": [ { "id": "A0A4X1TLP9", "url": "https://omabrowser.org/oma/group/A0A4X1TLP9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CQP0-1", "protein_name": "Large ribosomal subunit protein bL33m", "gene_name": "Mrpl33", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLSAVSFAKSKSKTILVKLVSQAGTGFSFNHKRSRLREKLSLLHYDPIVNKKVLFVEQKKIRSL", "length": 65 }, "evidence": [ { "id": "A0A4X1TLP9", "url": "https://omabrowser.org/oma/group/A0A4X1TLP9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLP9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLP9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLP9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLP9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TLU6-1", "uniprot_ac": "A0A4X1TLU6", "uniprot_id": "A0A4X1TLU6_PIG", "mass": { "chemical_mass": 31048.0, "monoisotopic_mass": 31048.0 }, "refseq": { "ac": "XP_020919057", "name": "neurexophilin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919057" }, "gene_names": [ { "name": "NXPH1", "type": "recommended", "evidence": [ { "id": "A0A4X1TLU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6" } ] }, { "name": "NXPH1", "type": "synonym", "evidence": [ { "id": "XP_020919057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919057" } ] } ], "protein_names": [ { "name": "Neurexophilin", "type": "recommended", "evidence": [ { "id": "A0A4X1TLU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6/entry#names_and_taxonomy" } ] }, { "name": "neurexophilin-1", "type": "synonym", "evidence": [ { "id": "XP_020919057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919057" } ] } ], "function": [ { "annotation": "May be signaling molecules that resemble neuropeptides.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLU6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6#function" }, { "database": "UniProtKB", "id": "PIRNR038019", "url": "https://www.uniprot.org/uniprotkb/PIRNR038019#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLU6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NXPH1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6", "locus": { "chromosome": "9", "start_pos": 78961848, "end_pos": 78653987, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037207", "url": "https://www.ensembl.org/id/ENSSSCG00000037207" } ] } } ], "crossref": [ { "id": "A0A4X1TLU6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TLU6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100511893", "url": "https://www.ncbi.nlm.nih.gov/gene/100511893", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511893", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511893", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FCFQVTC", "url": "https://omabrowser.org/oma/group/FCFQVTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TLU6", "url": "https://www.orthodb.org/?gene=A0A4X1TLU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17103:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17103:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06312", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06312", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020919057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919057", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TLU6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQAACWYVLLLLQPTVYLVTCANLTNGGKSELLKSGSSKSTLKHIWTESSKDLSISRLLSQTFRGKENDTDLDLRYDTPEPYSEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQQTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICIYISFYSTDYKLVQKVCPDYNYHSDTPYFPSG", "length": 271, "header": "tr|A0A4X1TLU6-1|A0A4X1TLU6_PIG Isoform 1 of Neurexophilin OS=Sus scrofa OX=9823 GN=NXPH1 PE=3 SV=1 CANONICAL=A0A4X1TLU6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TLU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6/entry#A0A4X1TLU6-1", "sequence": { "sequence": "MQAACWYVLLLLQPTVYLVTCANLTNGGKSELLKSGSSKSTLKHIWTESSKDLSISRLLSQTFRGKENDTDLDLRYDTPEPYSEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQQTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICIYISFYSTDYKLVQKVCPDYNYHSDTPYFPSG", "length": 271, "header": "tr|A0A4X1TLU6-1|A0A4X1TLU6_PIG Isoform 1 of Neurexophilin OS=Sus scrofa OX=9823 GN=NXPH1 PE=3 SV=1 CANONICAL=A0A4X1TLU6-1" }, "locus": { "chromosome": "9", "start_pos": 78960844, "end_pos": 78654778, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016722.4", "url": "https://www.ensembl.org/id/ENSSSCT00000016722.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016276.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016276.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLU6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511893", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511893", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1N0Y9-1", "protein_name": "Neurexophilin", "gene_name": "nxph1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATCWCAVFLITPAVYLVSSAHASVPGKSELLKSGSPKSTLKHIWTESSKDLSISRLLSQTLHGKENATALDLHYDTPEPYSEQDLWDWLRNTTDPQDSRPRAKRRPMVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLTAQQSVIDAKDSKSFNCRIEYEKVERGSKNTLCNFDPSKTCFQEQTQSHVSWLCSKPFKVICIYISFYSTDYKLVQKVCPDYNYHSDTPYFPSG", "length": 272 }, "evidence": [ { "id": "A0A4X1TLU6", "url": "https://omabrowser.org/oma/group/A0A4X1TLU6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1NQI7-1", "protein_name": "Neurexophilin", "gene_name": "NXPH1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQAVYWCAVLLLQPTLYLVTCANLTNGGKSELLKSGSSKSTLKHIWTESSKDLSISRLLSQTFRGKENDTDLDLRYDAPETYTEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQQTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICIYISFYSTDYKLVQKVCPDYNYHSDTPYFPSG", "length": 271 }, "evidence": [ { "id": "A0A4X1TLU6", "url": "https://omabrowser.org/oma/group/A0A4X1TLU6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P58417-1", "protein_name": "Neurexophilin-1", "gene_name": "NXPH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQAACWYVLFLLQPTVYLVTCANLTNGGKSELLKSGSSKSTLKHIWTESSKDLSISRLLSQTFRGKENDTDLDLRYDTPEPYSEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQQTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICIYISFYSTDYKLVQKVCPDYNYHSDTPYFPSG", "length": 271 }, "evidence": [ { "id": "A0A4X1TLU6", "url": "https://omabrowser.org/oma/group/A0A4X1TLU6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61200-1", "protein_name": "Neurexophilin-1", "gene_name": "Nxph1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQAACWYVLLLLQPTVYLVTCANLTNGGKSELLKSGSSKSTLKHIWTESSKDLSISRLLSQTFRGKENDTDLDLRYDTPEPYSEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQQTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICIYISFYSTDYKLVQKVCPDYNYHSDTPYFPSG", "length": 271 }, "evidence": [ { "id": "A0A4X1TLU6", "url": "https://omabrowser.org/oma/group/A0A4X1TLU6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63366-1", "protein_name": "Neurexophilin-1", "gene_name": "Nxph1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQAACWYVLLLLQPTVYLVTCANLTNGGKSELLKSGNSKSTLKHIWTESSKDLSISRLLSQTFRGKENGTDLDLRYDTPEPYSEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQQTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICIYISFYSTDYKLVQKVCPDYNYHSDTPYFPSG", "length": 271 }, "evidence": [ { "id": "A0A4X1TLU6", "url": "https://omabrowser.org/oma/group/A0A4X1TLU6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLU6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLU6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6" } ], "pmid": "" }, { "name": "synaptic cleft", "id": "GO:0043083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043083", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLU6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLU6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLU6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLU6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 23, "end_pos": 25 }, { "start_pos": 68, "end_pos": 70 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TLW1-1", "uniprot_ac": "A0A4X1TLW1", "uniprot_id": "A0A4X1TLW1_PIG", "mass": { "chemical_mass": 17091.0, "monoisotopic_mass": 17091.0 }, "refseq": { "ac": "XP_005671096", "name": "protein atonal homolog 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671096" }, "gene_names": [ { "name": "ATOH7", "type": "recommended", "evidence": [ { "id": "A0A4X1TLW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ] }, { "name": "ATOH7", "type": "synonym", "evidence": [ { "id": "XP_005671096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671096" } ] } ], "protein_names": [ { "name": "Atonal bHLH transcription factor 7", "type": "synonym", "evidence": [ { "id": "A0A4X1TLW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1/entry#names_and_taxonomy" } ] }, { "name": "protein atonal homolog 7", "type": "synonym", "evidence": [ { "id": "XP_005671096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671096" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ATOH7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1", "locus": { "chromosome": "14", "start_pos": 71400980, "end_pos": 71401447, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021995", "url": "https://www.ensembl.org/id/ENSSSCG00000021995" } ] } } ], "crossref": [ { "id": "A0A4X1TLW1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TLW1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100624800", "url": "https://www.ncbi.nlm.nih.gov/gene/100624800", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624800", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624800", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WINLHCE", "url": "https://omabrowser.org/oma/group/WINLHCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TLW1", "url": "https://www.orthodb.org/?gene=A0A4X1TLW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19290:SF99", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19290:SF99", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005671096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671096", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSCKPCNPPAAAGARAAPPCTGGAAECAGTCAGAGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFGSERDWVNLHCEHFGRDHYLPFAGAKLPGESEPYGQRLFGFQPESFQMAS", "length": 155, "header": "tr|A0A4X1TLW1-1|A0A4X1TLW1_PIG Isoform 1 of Atonal bHLH transcription factor 7 OS=Sus scrofa OX=9823 GN=ATOH7 PE=4 SV=1 CANONICAL=A0A4X1TLW1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TLW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1/entry#A0A4X1TLW1-1", "sequence": { "sequence": "MKSCKPCNPPAAAGARAAPPCTGGAAECAGTCAGAGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFGSERDWVNLHCEHFGRDHYLPFAGAKLPGESEPYGQRLFGFQPESFQMAS", "length": 155, "header": "tr|A0A4X1TLW1-1|A0A4X1TLW1_PIG Isoform 1 of Atonal bHLH transcription factor 7 OS=Sus scrofa OX=9823 GN=ATOH7 PE=4 SV=1 CANONICAL=A0A4X1TLW1-1" }, "locus": { "chromosome": "14", "start_pos": 71401447, "end_pos": 71400983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023617.2", "url": "https://www.ensembl.org/id/ENSSSCT00000023617.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023438.1", "url": "https://www.ensembl.org/id/ENSSSCP00000023438.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624800", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624800", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BI88-1", "protein_name": "Atonal bHLH transcription factor 7", "gene_name": "ATOH7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKSCKPCNTAAGARAAPPCAGGAECAGTCAGAGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFGSERDWVNLHCEHFGRDHYLPFAGAKLPAETEPYGQRLFGFQPEPFQMAS", "length": 152 }, "evidence": [ { "id": "A0A4X1TLW1", "url": "https://omabrowser.org/oma/group/A0A4X1TLW1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O57598-1", "protein_name": "Transcription factor ATOH7", "gene_name": "ATOH7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKTCQSSHLDSGVESDIQCRSGSGCVVKCSTERMESAAKRRLAANARERRRMQGLNTAFDRLRKVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERYSTEREWINLHCEHFHPESYHHYTGQKVATDSDPYAQRIFSYHPEHFQIAN", "length": 151 }, "evidence": [ { "id": "A0A4X1TLW1", "url": "https://omabrowser.org/oma/group/A0A4X1TLW1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8N100-1", "protein_name": "Transcription factor ATOH7", "gene_name": "ATOH7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSCKPSGPPAGARVAPPCAGGTECAGTCAGAGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFGSERDWVGLHCEHFGRDHYLPFPGAKLPGESELYSQRLFGFQPEPFQMAT", "length": 152 }, "evidence": [ { "id": "A0A4X1TLW1", "url": "https://omabrowser.org/oma/group/A0A4X1TLW1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2E5-1", "protein_name": "Transcription factor Atoh7", "gene_name": "Atoh7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSACKPHGPPAGARGAPPCAGAAERAVSCAGPGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIIALTRILAEAERDWVGLRCEQRGRDHPYLPFPGARLQVDPEPYGQRLFGFQPEPFPMAS", "length": 149 }, "evidence": [ { "id": "A0A4X1TLW1", "url": "https://omabrowser.org/oma/group/A0A4X1TLW1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "neural retina development", "id": "GO:0003407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003407", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "response to auditory stimulus", "id": "GO:0010996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010996", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "neuron fate commitment", "id": "GO:0048663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048663", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "entrainment of circadian clock by photoperiod", "id": "GO:0043153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043153", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "positive regulation of retinal ganglion cell axon guidance", "id": "GO:1902336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902336", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "sensory organ development", "id": "GO:0007423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007423", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TLW1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TLW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLW1" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 95, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TM78-1", "uniprot_ac": "A0A4X1TM78", "uniprot_id": "A0A4X1TM78_PIG", "mass": { "chemical_mass": 6791.0, "monoisotopic_mass": 6791.0 }, "refseq": { "ac": "XP_020926659", "name": "Purkinje cell protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926659" }, "gene_names": [ { "name": "PCP4", "type": "recommended", "evidence": [ { "id": "A0A4X1TM78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78" } ] }, { "name": "PCP4", "type": "synonym", "evidence": [ { "id": "XP_020926659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926659" } ] } ], "protein_names": [ { "name": "Purkinje cell protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020926659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926659" } ] }, { "name": "Purkinje cell protein 4", "type": "synonym", "evidence": [ { "id": "A0A4X1TM78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TM78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PCP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78", "locus": { "chromosome": "13", "start_pos": 203479209, "end_pos": 203412479, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037110", "url": "https://www.ensembl.org/id/ENSSSCG00000037110" } ] } } ], "crossref": [ { "id": "A0A4X1TM78", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TM78", "database": "AlphaFoldDB", "categories": [] }, { "id": "110256491", "url": "https://www.ncbi.nlm.nih.gov/gene/110256491", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110256491", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110256491", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHCEGQM", "url": "https://omabrowser.org/oma/group/PHCEGQM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TM78", "url": "https://www.orthodb.org/?gene=A0A4X1TM78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15359:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15359:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_020926659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926659", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TM78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TM78-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSERQGAGATNGKDKTSGENDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS", "length": 62, "header": "tr|A0A4X1TM78-1|A0A4X1TM78_PIG Isoform 1 of Purkinje cell protein 4 OS=Sus scrofa OX=9823 GN=PCP4 PE=3 SV=1 CANONICAL=A0A4X1TM78-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TM78-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78/entry#A0A4X1TM78-1", "sequence": { "sequence": "MSERQGAGATNGKDKTSGENDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS", "length": 62, "header": "tr|A0A4X1TM78-1|A0A4X1TM78_PIG Isoform 1 of Purkinje cell protein 4 OS=Sus scrofa OX=9823 GN=PCP4 PE=3 SV=1 CANONICAL=A0A4X1TM78-1" }, "locus": { "chromosome": "13", "start_pos": 203478931, "end_pos": 203412646, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064115.2", "url": "https://www.ensembl.org/id/ENSSSCT00000064115.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031224.1", "url": "https://www.ensembl.org/id/ENSSSCP00000031224.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TM78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110256491", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110256491", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P48539-1", "protein_name": "Calmodulin regulator protein PCP4", "gene_name": "PCP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSERQGAGATNGKDKTSGENDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS", "length": 62 }, "evidence": [ { "id": "A0A4X1TM78", "url": "https://omabrowser.org/oma/group/A0A4X1TM78/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P63054-1", "protein_name": "Calmodulin regulator protein PCP4", "gene_name": "Pcp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSERQSAGATNGKDKTSGDNDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS", "length": 62 }, "evidence": [ { "id": "A0A4X1TM78", "url": "https://omabrowser.org/oma/group/A0A4X1TM78/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P63055-1", "protein_name": "Calmodulin regulator protein PCP4", "gene_name": "Pcp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSERQSAGATNGKDKTSGDNDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS", "length": 62 }, "evidence": [ { "id": "A0A4X1TM78", "url": "https://omabrowser.org/oma/group/A0A4X1TM78/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q148C4-1", "protein_name": "Calmodulin regulator protein PCP4", "gene_name": "PCP4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSERQGAGTTNGKDKPSGENDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS", "length": 62 }, "evidence": [ { "id": "A0A4X1TM78", "url": "https://omabrowser.org/oma/group/A0A4X1TM78/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TM78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TM78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TM78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TM78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TM78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78" } ], "pmid": "" }, { "name": "positive regulation of CAMKK-AMPK signaling cascade", "id": "GO:1905291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905291", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TM78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TM78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TMS6-1", "uniprot_ac": "A0A4X1TMS6", "uniprot_id": "A0A4X1TMS6_PIG", "mass": { "chemical_mass": 55993.0, "monoisotopic_mass": 55993.0 }, "refseq": { "ac": "XP_001927907", "name": "enhancer of mRNA-decapping protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927907" }, "gene_names": [ { "name": "EDC3", "type": "recommended", "evidence": [ { "id": "A0A4X1TMS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6" } ] }, { "name": "EDC3", "type": "synonym", "evidence": [ { "id": "XP_001927907", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927907" } ] } ], "protein_names": [ { "name": "Enhancer of mRNA-decapping protein 3", "type": "recommended", "evidence": [ { "id": "A0A4X1TMS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6/entry#names_and_taxonomy" } ] }, { "name": "YjeF domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A4X1TMS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6/entry#names_and_taxonomy" } ] }, { "name": "enhancer of mRNA-decapping protein 3", "type": "synonym", "evidence": [ { "id": "XP_001927907", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927907" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TMS6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EDC3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6", "locus": { "chromosome": "7", "start_pos": 58897919, "end_pos": 58828727, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001903", "url": "https://www.ensembl.org/id/ENSSSCG00000001903" } ] } } ], "crossref": [ { "id": "A0A4X1TMS6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TMS6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01737", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01737", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156966", "url": "https://www.ncbi.nlm.nih.gov/gene/100156966", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156966", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156966", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NHQWPKI", "url": "https://omabrowser.org/oma/group/NHQWPKI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TMS6", "url": "https://www.orthodb.org/?gene=A0A4X1TMS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13612", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13612", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13612:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13612:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-430039", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-430039", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001927907", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927907", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TMS6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TMS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TMT6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TMT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGENQHFGDLHQAELGPSGVGCQVGIGQNGMGKLVKKPASSSSAPQNIPKRTDVKSQDVAVSPQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGSRSRGIPNERPTRYRHDENILESEPIVYRRITVPHNVSKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNIHQRPTVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFMKMLESITNELSLFSKTQGQQVSSLKDLPTSPVDLVINCLDCPENAFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRVYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA", "length": 508, "header": "tr|A0A4X1TMS6-1|A0A4X1TMS6_PIG Isoform 1 of Enhancer of mRNA-decapping protein 3 OS=Sus scrofa OX=9823 GN=EDC3 PE=3 SV=1 CANONICAL=A0A4X1TMS6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TMS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6/entry#A0A4X1TMS6-1", "sequence": { "sequence": "MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGENQHFGDLHQAELGPSGVGCQVGIGQNGMGKLVKKPASSSSAPQNIPKRTDVKSQDVAVSPQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGSRSRGIPNERPTRYRHDENILESEPIVYRRITVPHNVSKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNIHQRPTVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFMKMLESITNELSLFSKTQGQQVSSLKDLPTSPVDLVINCLDCPENAFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRVYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA", "length": 508, "header": "tr|A0A4X1TMS6-1|A0A4X1TMS6_PIG Isoform 1 of Enhancer of mRNA-decapping protein 3 OS=Sus scrofa OX=9823 GN=EDC3 PE=3 SV=1 CANONICAL=A0A4X1TMS6-1" }, "locus": { "chromosome": "7", "start_pos": 58892799, "end_pos": 58850410, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002132.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002132.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002082.2", "url": "https://www.ensembl.org/id/ENSSSCP00000002082.2" } ] } }, { "isoform_ac": "A0A4X1TMT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6/entry#A0A4X1TMT6-1", "sequence": { "sequence": "MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGENQHFGDLHQAELGPSGVGCQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGSRSRGIPNERPTRYRHDENILESEPIVYRRITVPHNVSKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNIHQRPTVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFMKMLESITNELSLFSKTQGQQVSSLKDLPTSPVDLVINCLDCPENAFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRVYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA", "length": 467, "header": "tr|A0A4X1TMT6-1|A0A4X1TMT6_PIG Computationally mapped isoform of Enhancer of mRNA-decapping protein 3 OS=Sus scrofa OX=9823 GN=EDC3 PE=3 SV=1 CANONICAL=A0A4X1TMS6-1" }, "locus": { "chromosome": "7", "start_pos": 58892799, "end_pos": 58850410, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041525.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041525.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052693.1", "url": "https://www.ensembl.org/id/ENSSSCP00000052693.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TMS6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156966", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156966", "resource": "KEGG Pathway" }, { "id": "R-SSC-430039", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-430039", "resource": "Reactome", "description": "mRNA decay by 5' to 3' exoribonuclease" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BEA2-1", "protein_name": "Enhancer of mRNA-decapping protein 3", "gene_name": "EDC3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGETQHFGDLHQTELGSSGVGCQVGINQNGTGKLVKKPASSSSVPQNIPKRTDVKSQDVAISPQQQQCSKSYVDRHTESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGTRSRGIPNERPTRYRHDENILESEPIVYRRITVPHNVSKEFCTDSGLVVPSISYELHKKLLAVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPAVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLKDLPTSPVDLVINCLDCPENAFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEGEQGIDAKWSLALGLPLPLGEHAGRVYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA", "length": 508 }, "evidence": [ { "id": "A0A4X1TMS6", "url": "https://omabrowser.org/oma/group/A0A4X1TMS6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1M7Z1-1", "protein_name": "Enhancer of mRNA-decapping protein 3", "gene_name": "Edc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EAMDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGDNQQFGDLHQTELGPSGVGYQMSINQNGTGKVVKKPASSSSAPQSIPKRTDMKSQDVAISPQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGSRSRGVPNERPARYRHDENILESEPIVYRRITVPHSVSKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLRDLPTSPVDLVINCLDCPENAFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRVYLCDIGIPQQVFQEVGIDYHSPFGCKFVIPLHSA", "length": 508 }, "evidence": [ { "id": "A0A4X1TMS6", "url": "https://omabrowser.org/oma/group/A0A4X1TMS6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q502M5-1", "protein_name": "Enhancer of mRNA-decapping protein 3", "gene_name": "edc3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALDWVGNLVSIHCGPTLGVYQGEISSVDQTSQTISLRNPFHNGVKCTVPEVTFSAMDIKDLKILEISKNSIEVSKQNGPESSSTTLMPHVGRKDKGGGGGGGGAPANSAPVMVPNKAEPRLQEGGVSPVPHYSKSYGERHIDMAVQGKGFRRRHNSWSSSCRGPNQATPKKNGLKNGGHMKNKDDECFGDGMDDVLDEDFDFEGNLALFDKAAVLSQIESSERRGNGARSRGTPGEQTPSRYRHDENILEAKPVVYRQITVPQNGSKEYSTDSGLVVPSISFELHKRLLAAAESHGLSLERRLEMTGVCASQMALTLLGGPNRLTPKNVHQRPTVALLCGPHVQGAQGISCGRHLANHEVEVVLFLPNFVKMLEAITSELALFGKTGGRLVSNVKDLPETPVDLVINCLDSHENGFLRDQPWYKAAADWANQNRAPVLSIDPPVSGQAHAVEAKWSLSLGLPLPLSEGAGRVYPCDIGIPRQVFQEVGIKYHSPFGCKFVIPLHSE", "length": 507 }, "evidence": [ { "id": "A0A4X1TMS6", "url": "https://omabrowser.org/oma/group/A0A4X1TMS6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K2D3-1", "protein_name": "Enhancer of mRNA-decapping protein 3", "gene_name": "Edc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGDNQQVGDLHQTELGPSGVGYQMSISQNGTGKVVKKPASSSSAPQSIPKRTDVKSQDVAISPQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEELPDTDFDFEGNLALFDKAAVFEEIDTYERRSGSRSRGVPNERPARYRHDENILESEPIVYRRITVPHSVSKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLRDLPASPVDLVINCLDCPENAFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRVYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA", "length": 508 }, "evidence": [ { "id": "A0A4X1TMS6", "url": "https://omabrowser.org/oma/group/A0A4X1TMS6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96F86-1", "protein_name": "Enhancer of mRNA-decapping protein 3", "gene_name": "EDC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGDNQHFGDLHQTELGPSGAGCQVGINQNGTGKFVKKPASSSSAPQNIPKRTDVKSQDVAVSPQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGTRSRGIPNERPTRYRHDENILESEPIVYRRIIVPHNVSKEFCTDSGLVVPSISYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLKDLPTSPVDLVINCLDCPENVFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRIYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA", "length": 508 }, "evidence": [ { "id": "A0A4X1TMS6", "url": "https://omabrowser.org/oma/group/A0A4X1TMS6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TMS6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TMS6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TMS6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "P-body assembly", "id": "GO:0033962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033962", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TMS6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6" } ], "pmid": "" }, { "name": "deadenylation-independent decapping of nuclear-transcribed mRNA", "id": "GO:0031087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031087", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TMS6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TMS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6" }, { "id": "PS51512", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51512" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DFDF", "eco_id": "ECO_0000259", "start_pos": 192, "end_pos": 228, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TMS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6" }, { "id": "PS52002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sm", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 68, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TMS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TMS6" }, { "id": "PS51385", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "YjeF N-terminal", "eco_id": "ECO_0000259", "start_pos": 283, "end_pos": 487, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TN77-1", "uniprot_ac": "A0A4X1TN77", "uniprot_id": "A0A4X1TN77_PIG", "mass": { "chemical_mass": 38018.0, "monoisotopic_mass": 38018.0 }, "refseq": { "ac": "XP_013848054", "name": "clavesin-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013848054" }, "gene_names": [ { "name": "CLVS2", "type": "recommended", "evidence": [ { "id": "A0A4X1TN77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77" } ] }, { "name": "CLVS2", "type": "synonym", "evidence": [ { "id": "XP_013848054", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013848054" } ] } ], "protein_names": [ { "name": "Clavesin-2", "type": "recommended", "evidence": [ { "id": "A0A4X1TN77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77/entry#names_and_taxonomy" } ] }, { "name": "Retinaldehyde-binding protein 1-like 2", "type": "synonym", "evidence": [ { "id": "A0A4X1TN77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77/entry#names_and_taxonomy" } ] }, { "name": "clavesin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013848054", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013848054" } ] } ], "function": [ { "annotation": "Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77#function" }, { "database": "UniProtKB", "id": "ARBA00046144", "url": "https://www.uniprot.org/uniprotkb/ARBA00046144#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CLVS2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77", "locus": { "chromosome": "1", "start_pos": 39682689, "end_pos": 39752486, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004232", "url": "https://www.ensembl.org/id/ENSSSCG00000004232" } ] } } ], "crossref": [ { "id": "A0A4X1TN77", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TN77", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155458", "url": "https://www.ncbi.nlm.nih.gov/gene/100155458", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155458", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155458", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DEEPDYC", "url": "https://omabrowser.org/oma/group/DEEPDYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TN77", "url": "https://www.orthodb.org/?gene=A0A4X1TN77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10174:SF73", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10174:SF73", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-432720", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432720", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013848054", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013848054", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TN77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TN77-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYSMPVKDMEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD", "length": 327, "header": "tr|A0A4X1TN77-1|A0A4X1TN77_PIG Isoform 1 of Clavesin-2 OS=Sus scrofa OX=9823 GN=CLVS2 PE=1 SV=1 CANONICAL=A0A4X1TN77-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TN77-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77/entry#A0A4X1TN77-1", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYSMPVKDMEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD", "length": 327, "header": "tr|A0A4X1TN77-1|A0A4X1TN77_PIG Isoform 1 of Clavesin-2 OS=Sus scrofa OX=9823 GN=CLVS2 PE=1 SV=1 CANONICAL=A0A4X1TN77-1" }, "locus": { "chromosome": "1", "start_pos": 39751168, "end_pos": 39685815, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051787.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051787.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031602.1", "url": "https://www.ensembl.org/id/ENSSSCP00000031602.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155458", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155458", "resource": "KEGG Pathway" }, { "id": "R-SSC-432720", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432720", "resource": "Reactome", "description": "Lysosome Vesicle Biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A6JUQ6-1", "protein_name": "Clavesin-2", "gene_name": "Clvs2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYSMPVNEVDKELSPKSMKRSQSVVDPTALKRMDKSEEENMQPLLSLD", "length": 327 }, "evidence": [ { "id": "A0A4X1TN77", "url": "https://omabrowser.org/oma/group/A0A4X1TN77/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BHP4-1", "protein_name": "Clavesin-2", "gene_name": "CLVS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYSVDSYSMPVKEVEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD", "length": 327 }, "evidence": [ { "id": "A0A4X1TN77", "url": "https://omabrowser.org/oma/group/A0A4X1TN77/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1C6S0-1", "protein_name": "Clavesin-2", "gene_name": "CLVS2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFQHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSECNVDSYNAPAKDIEKDLSPKSMKRSQSVVDPGVLKRMDKNEEENMQPLLSLD", "length": 327 }, "evidence": [ { "id": "A0A4X1TN77", "url": "https://omabrowser.org/oma/group/A0A4X1TN77/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HKL3-1", "protein_name": "Clavesin-2", "gene_name": "Clvs2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYSMPVKEVEKELSPKSMKRSQSVVDPTALKRMDKSEEENMQPLLSLD", "length": 327 }, "evidence": [ { "id": "A0A4X1TN77", "url": "https://omabrowser.org/oma/group/A0A4X1TN77/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5SPP0-1", "protein_name": "Clavesin-2", "gene_name": "clvs2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTHLQAGLSPETLEKAKVELKENPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFKNLKATDPGIKQALKDGFPGVLSNLDRYGRKILVLFAANWDQSRYTFVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNNLNSLHQLILPEILPSELGGMLPPYDMGTWARTLLDHAYDEETDYCPESYTLSVKDLEKDLSPKTMKRSQSVVEPGVLKRPEKVKSEEENMQPLLSLD", "length": 329 }, "evidence": [ { "id": "A0A4X1TN77", "url": "https://omabrowser.org/oma/group/A0A4X1TN77/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5SYC1-1", "protein_name": "Clavesin-2", "gene_name": "CLVS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYSMPVKEVEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD", "length": 327 }, "evidence": [ { "id": "A0A4X1TN77", "url": "https://omabrowser.org/oma/group/A0A4X1TN77/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BG92-1", "protein_name": "Clavesin-2", "gene_name": "Clvs2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPNMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYNMPVKDVDKELSPKSMKRSQSVVDPTALKRMDKSEEENMQPLLALD", "length": 327 }, "evidence": [ { "id": "A0A4X1TN77", "url": "https://omabrowser.org/oma/group/A0A4X1TN77/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol bisphosphate binding", "id": "GO:1902936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902936", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080025", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lysosome organization", "id": "GO:0007040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007040", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TN77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN77" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 257, "start_aa": "Ile", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TN99-1", "uniprot_ac": "A0A4X1TN99", "uniprot_id": "A0A4X1TN99_PIG", "mass": { "chemical_mass": 31331.0, "monoisotopic_mass": 31331.0 }, "refseq": { "ac": "XP_003130224", "name": "transmembrane protein 106B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130224" }, "gene_names": [ { "name": "TMEM106B", "type": "recommended", "evidence": [ { "id": "A0A4X1TN99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" } ] }, { "name": "TMEM106B", "type": "synonym", "evidence": [ { "id": "XP_003130224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130224" } ] } ], "protein_names": [ { "name": "Transmembrane protein 106B", "type": "recommended", "evidence": [ { "id": "A0A4X1TN99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 106B", "type": "synonym", "evidence": [ { "id": "XP_003130224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130224" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMEM106B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99", "locus": { "chromosome": "9", "start_pos": 81864210, "end_pos": 81837667, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000032740", "url": "https://www.ensembl.org/id/ENSSSCG00000032740" } ] } } ], "crossref": [ { "id": "A0A4X1TN99", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TN99", "database": "AlphaFoldDB", "categories": [] }, { "id": "100512621", "url": "https://www.ncbi.nlm.nih.gov/gene/100512621", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512621", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512621", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FGHSEQT", "url": "https://omabrowser.org/oma/group/FGHSEQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TN99", "url": "https://www.orthodb.org/?gene=A0A4X1TN99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28556", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28556", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28556:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28556:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003130224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130224", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TN99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TN99-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKSFSHLPLHSNKEDAYDAVTSTENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIYLNITNTLNITNNNYYSVEVENIIAQVQFSKTVIGKARLNNITKIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTTYQLGQSEYLNVLQPQQ", "length": 275, "header": "tr|A0A4X1TN99-1|A0A4X1TN99_PIG Isoform 1 of Transmembrane protein 106B OS=Sus scrofa OX=9823 GN=TMEM106B PE=1 SV=1 CANONICAL=A0A4X1TN99-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TN99-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99/entry#A0A4X1TN99-1", "sequence": { "sequence": "MGKSFSHLPLHSNKEDAYDAVTSTENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIYLNITNTLNITNNNYYSVEVENIIAQVQFSKTVIGKARLNNITKIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTTYQLGQSEYLNVLQPQQ", "length": 275, "header": "tr|A0A4X1TN99-1|A0A4X1TN99_PIG Isoform 1 of Transmembrane protein 106B OS=Sus scrofa OX=9823 GN=TMEM106B PE=1 SV=1 CANONICAL=A0A4X1TN99-1" }, "locus": { "chromosome": "9", "start_pos": 81858051, "end_pos": 81840462, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046979.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046979.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051024.3", "url": "https://www.ensembl.org/id/ENSSSCP00000051024.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512621", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512621", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PUI5-1", "protein_name": "Transmembrane protein 106B", "gene_name": "TMEM106B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKKMGKSLSHLPIHTCKEDGYDGGTVSDNMRNGLVHSESHGEDGRCGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVTASVIVCLLLSGLAVFFLFPRSVDVEYIGVKSVYVNYEQSRRIIYLNITNTLNITNNNYYSVEVANITAQVQFSKTVIGKARLNNITNIGPLDMKQIDYMVPTVIQDEMSYMFDFCTLASIKVHNIVVMMQVTVTTSYFGHSEQISREKYQYVDCGGNTTYQLGQSEYLNVLQPPQ", "length": 278 }, "evidence": [ { "id": "A0A4X1TN99", "url": "https://omabrowser.org/oma/group/A0A4X1TN99/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GW36-1", "protein_name": "Transmembrane protein 106B", "gene_name": "Tmem106b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGKSLSHLPLHSNKEDGYDGVTSTDSMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVSVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDFQKRTIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLNNITNIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTTYQLAQSEYLNVLQPQQ", "length": 275 }, "evidence": [ { "id": "A0A4X1TN99", "url": "https://omabrowser.org/oma/group/A0A4X1TN99/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1LWC2-1", "protein_name": "Transmembrane protein 106B", "gene_name": "tmem106b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKALSHVAKHTCHDECQDSLTSSPGYSAMQTDDSKSGGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVILCLLLCTLAVFFLFPRSIDVNYVGVKSVYVSYDQSKRIVYLNVTNSLNITNNNYYSVDVANITARVQFSQTVIGKTRISNITTIGPLDMKQIDYMVPTTIADEMSYMYDYCTLQSIKVHNIVVMMQITVTTVYFGHAEQVSQEMYQYVDCGGNTTALHEYSLNTPLTG", "length": 267 }, "evidence": [ { "id": "A0A4X1TN99", "url": "https://omabrowser.org/oma/group/A0A4X1TN99/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3ZC25-1", "protein_name": "Transmembrane protein 106B", "gene_name": "TMEM106B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGKSFSHLPLHSNKEDGYDGMTSTENIRNGLVNGEVHNEDGRSGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLNNITSIGPLDMKQIDYTVPTVIAEEMSYMFDFCTLLTIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTTYHLGQSEYLNVLQPQQ", "length": 275 }, "evidence": [ { "id": "A0A4X1TN99", "url": "https://omabrowser.org/oma/group/A0A4X1TN99/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AYA5-1", "protein_name": "Transmembrane protein 106B", "gene_name": "Tmem106b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKSLSHLPLHSNKEDGYDGVTSTDNMRNGLVSSEVRNEDGRSGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDSQKRMIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLSNITNIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLPSIKVHNIVLMMQVTVTTAYFGHSEQISQERYQYVDCGRNTTYQLAQSEYLNVLQPQQ", "length": 275 }, "evidence": [ { "id": "A0A4X1TN99", "url": "https://omabrowser.org/oma/group/A0A4X1TN99/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80X71-1", "protein_name": "Transmembrane protein 106B", "gene_name": "Tmem106b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKSLSHLPLHSNKEDGYDGVTSTDNMRNGLVSSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIEVKYIGVKSAYVSYDAEKRTIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLNNITNIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLLSIKVHNIVLMMQVTVTTAYFGHSEQISQERYQYVDCGRNTTYQLAQSEYLNVLQPQQ", "length": 275 }, "evidence": [ { "id": "A0A4X1TN99", "url": "https://omabrowser.org/oma/group/A0A4X1TN99/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUM4-1", "protein_name": "Transmembrane protein 106B", "gene_name": "TMEM106B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKSLSHLPLHSSKEDAYDGVTSENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLNNITIIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTTYQLGQSEYLNVLQPQQ", "length": 274 }, "evidence": [ { "id": "A0A4X1TN99", "url": "https://omabrowser.org/oma/group/A0A4X1TN99/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "lysosome organization", "id": "GO:0007040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007040", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" } ], "pmid": "" }, { "name": "lysosomal transport", "id": "GO:0007041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007041", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TN99", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TN99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" }, { "id": "PF07092", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07092" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein 106 C-terminal", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 259, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TN99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TN99" }, { "id": "PF21002", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein 106 N-terminal", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 96, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 257, "end_pos": 259 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TNB9-1", "uniprot_ac": "A0A4X1TNB9", "uniprot_id": "A0A4X1TNB9_PIG", "mass": { "chemical_mass": 59685.0, "monoisotopic_mass": 59685.0 }, "refseq": {}, "gene_names": [ { "name": "TENT4A", "type": "recommended", "evidence": [ { "id": "A0A4X1TNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ] } ], "protein_names": [ { "name": "Terminal nucleotidyltransferase 4A", "type": "recommended", "evidence": [ { "id": "A0A4X1TNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.19", "type": "synonym", "evidence": [ { "id": "A0A4X1TNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9/entry#names_and_taxonomy" } ] }, { "name": "DNA polymerase sigma", "type": "synonym", "evidence": [ { "id": "A0A4X1TNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9/entry#names_and_taxonomy" } ] }, { "name": "Non-canonical poly(A) RNA polymerase PAPD7", "type": "synonym", "evidence": [ { "id": "A0A4X1TNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9/entry#names_and_taxonomy" } ] }, { "name": "PAP-associated domain-containing protein 7", "type": "synonym", "evidence": [ { "id": "A0A4X1TNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9/entry#names_and_taxonomy" } ] }, { "name": "TRAMP-like complex polyadenylate polymerase", "type": "synonym", "evidence": [ { "id": "A0A4X1TNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9/entry#names_and_taxonomy" } ] }, { "name": "Terminal guanylyltransferase", "type": "synonym", "evidence": [ { "id": "A0A4X1TNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Terminal nucleotidyltransferase that catalyzes preferentially the transfer of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation. Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9#function" }, { "database": "UniProtKB", "id": "ARBA00054414", "url": "https://www.uniprot.org/uniprotkb/ARBA00054414#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TENT4A", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9", "locus": { "chromosome": "16", "start_pos": 75217219, "end_pos": 75258556, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017102", "url": "https://www.ensembl.org/id/ENSSSCG00000017102" } ] } } ], "crossref": [ { "id": "A0A4X1TNB9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TNB9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05402", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05402", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054708", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054708", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23092:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23092:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03828", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03828", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "11332", "url": "https://www.rhea-db.org/rhea/11332", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TNB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPCPEEAAMRREVVKRIETVVKDLWPTAEVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQALRKHKVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHPRIDARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDSESTLGRIVKVTQEVIDYRRWIKEKWGSRARPAPDLDNRIKIKEHVGVCEGEQPPRRDAESPYGQRLTLSLPSPQLLSSGSSASSVSSLSGSDIDSDTPPCTTPSVYQFSLQAPTPLLASLPAALPVPSGKPQPSTSRTLVMTTTTQTRFTIPPPALGVGPVPCRQAGLEGAPALKAVHHVSPPALPAGSPNPLSSPHLYHKHSGMKLSMKGSHNHGQGGSYSSVGTGGVRPPVGNRGHHQYNRTGWRRKKHTHTRDSLPVSLSR", "length": 541, "header": "tr|A0A4X1TNB9-1|A0A4X1TNB9_PIG Isoform 1 of Terminal nucleotidyltransferase 4A OS=Sus scrofa OX=9823 GN=TENT4A PE=3 SV=1 CANONICAL=A0A4X1TNB9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TNB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9/entry#A0A4X1TNB9-1", "sequence": { "sequence": "MSPCPEEAAMRREVVKRIETVVKDLWPTAEVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQALRKHKVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHPRIDARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDSESTLGRIVKVTQEVIDYRRWIKEKWGSRARPAPDLDNRIKIKEHVGVCEGEQPPRRDAESPYGQRLTLSLPSPQLLSSGSSASSVSSLSGSDIDSDTPPCTTPSVYQFSLQAPTPLLASLPAALPVPSGKPQPSTSRTLVMTTTTQTRFTIPPPALGVGPVPCRQAGLEGAPALKAVHHVSPPALPAGSPNPLSSPHLYHKHSGMKLSMKGSHNHGQGGSYSSVGTGGVRPPVGNRGHHQYNRTGWRRKKHTHTRDSLPVSLSR", "length": 541, "header": "tr|A0A4X1TNB9-1|A0A4X1TNB9_PIG Isoform 1 of Terminal nucleotidyltransferase 4A OS=Sus scrofa OX=9823 GN=TENT4A PE=3 SV=1 CANONICAL=A0A4X1TNB9-1" }, "locus": { "chromosome": "16", "start_pos": 75232824, "end_pos": 75219199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086621.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086621.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069809.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069809.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 379, "start_aa": "Thr", "end_pos": 379, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr379", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "pmid": "" }, { "name": "TRAMP complex", "id": "GO:0031499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031499", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "pmid": "" }, { "name": "poly(A) RNA polymerase activity", "id": "GO:1990817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990817", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "pmid": "" }, { "name": "guanylyltransferase activity", "id": "GO:0070568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070568", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "pmid": "" }, { "name": "RNA 3'-end processing", "id": "GO:0031123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031123", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "pmid": "" }, { "name": "positive regulation of 3'-UTR-mediated mRNA stabilization", "id": "GO:1905870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905870", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "pmid": "" }, { "name": "negative regulation of nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0060212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060212", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "pmid": "" }, { "name": "polyadenylation-dependent ncRNA catabolic process", "id": "GO:0043634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNB9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11332", "name": "", "equation": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "11332", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11332" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" }, { "id": "PF03828", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03828" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PAP-associated", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 237, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNB9" }, { "id": "PF22600", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22600" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Poly(A) RNA polymerase mitochondrial-like central palm", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 121, "start_aa": "Pro", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 379 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 519, "end_pos": 521 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TNF0-1", "uniprot_ac": "A0A4X1TNF0", "uniprot_id": "A0A4X1TNF0_PIG", "mass": { "chemical_mass": 13596.0, "monoisotopic_mass": 13596.0 }, "refseq": { "ac": "XP_020958082", "name": "replication protein A 14 kDa subunit", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958082" }, "gene_names": [ { "name": "RPA3", "type": "recommended", "evidence": [ { "id": "A0A4X1TNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ] }, { "name": "RPA3", "type": "synonym", "evidence": [ { "id": "XP_020958082", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958082" } ] } ], "protein_names": [ { "name": "Replication protein A 14 kDa subunit", "type": "recommended", "evidence": [ { "id": "A0A4X1TNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0/entry#names_and_taxonomy" } ] }, { "name": "Replication factor A protein 3", "type": "synonym", "evidence": [ { "id": "A0A4X1TNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0/entry#names_and_taxonomy" } ] }, { "name": "replication protein A 14 kDa subunit", "type": "synonym", "evidence": [ { "id": "XP_020958082", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958082" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPA3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0", "locus": { "chromosome": "9", "start_pos": 77910881, "end_pos": 77937060, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000023886", "url": "https://www.ensembl.org/id/ENSSSCG00000023886" } ] } } ], "crossref": [ { "id": "A0A4X1TNF0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TNF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04479", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04479", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100624116", "url": "https://www.ncbi.nlm.nih.gov/gene/100624116", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624116", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624116", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HEFPEYY", "url": "https://omabrowser.org/oma/group/HEFPEYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TNF0", "url": "https://www.orthodb.org/?gene=A0A4X1TNF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15114", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15114", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15114:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15114:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-110312", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110312", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-110314", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110314", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-110320", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174437", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174437", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-176187", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176187", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3371453", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5358565", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358565", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5358606", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358606", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5651801", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5651801", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5655862", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5655862", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5656121", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656121", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5656169", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656169", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5685938", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5685938", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5685942", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5685942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5693537", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693537", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5693607", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693607", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5696395", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696395", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5696397", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696397", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5696400", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696400", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6782135", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782135", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6782210", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6804756", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804756", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68962", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68962", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-69166", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-69473", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69473", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020958082", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958082", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TNF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDVMELPKSRINASMVTQFIDQPVCFVGRLEKIHPTGKMFILSDGEGKNVTIELMEPLDEEISGIVEVVGRVTGKATIMCVSYIQFKEDNHPFDLGLYNEAVKIIHEFPQYFPLGVVQHG", "length": 121, "header": "tr|A0A4X1TNF0-1|A0A4X1TNF0_PIG Isoform 1 of Replication protein A 14 kDa subunit OS=Sus scrofa OX=9823 GN=RPA3 PE=1 SV=1 CANONICAL=A0A4X1TNF0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TNF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0/entry#A0A4X1TNF0-1", "sequence": { "sequence": "MVDVMELPKSRINASMVTQFIDQPVCFVGRLEKIHPTGKMFILSDGEGKNVTIELMEPLDEEISGIVEVVGRVTGKATIMCVSYIQFKEDNHPFDLGLYNEAVKIIHEFPQYFPLGVVQHG", "length": 121, "header": "tr|A0A4X1TNF0-1|A0A4X1TNF0_PIG Isoform 1 of Replication protein A 14 kDa subunit OS=Sus scrofa OX=9823 GN=RPA3 PE=1 SV=1 CANONICAL=A0A4X1TNF0-1" }, "locus": { "chromosome": "9", "start_pos": 77914683, "end_pos": 77911193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027813.3", "url": "https://www.ensembl.org/id/ENSSSCT00000027813.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022985.1", "url": "https://www.ensembl.org/id/ENSSSCP00000022985.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624116", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624116", "resource": "KEGG Pathway" }, { "id": "R-SSC-110312", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110312", "resource": "Reactome", "description": "Translesion synthesis by REV1" }, { "id": "R-SSC-110314", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110314", "resource": "Reactome", "description": "Recognition of DNA damage by PCNA-containing replication complex" }, { "id": "R-SSC-110320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110320", "resource": "Reactome", "description": "Translesion Synthesis by POLH" }, { "id": "R-SSC-174437", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174437", "resource": "Reactome", "description": "Removal of the Flap Intermediate from the C-strand" }, { "id": "R-SSC-176187", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176187", "resource": "Reactome", "description": "Activation of ATR in response to replication stress" }, { "id": "R-SSC-3371453", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "resource": "Reactome", "description": "Regulation of HSF1-mediated heat shock response" }, { "id": "R-SSC-5358565", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358565", "resource": "Reactome", "description": "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" }, { "id": "R-SSC-5358606", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358606", "resource": "Reactome", "description": "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" }, { "id": "R-SSC-5651801", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5651801", "resource": "Reactome", "description": "PCNA-Dependent Long Patch Base Excision Repair" }, { "id": "R-SSC-5655862", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5655862", "resource": "Reactome", "description": "Translesion synthesis by POLK" }, { "id": "R-SSC-5656121", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656121", "resource": "Reactome", "description": "Translesion synthesis by POLI" }, { "id": "R-SSC-5656169", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656169", "resource": "Reactome", "description": "Termination of translesion DNA synthesis" }, { "id": "R-SSC-5685938", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5685938", "resource": "Reactome", "description": "HDR through Single Strand Annealing (SSA)" }, { "id": "R-SSC-5685942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5685942", "resource": "Reactome", "description": "HDR through Homologous Recombination (HRR)" }, { "id": "R-SSC-5693537", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693537", "resource": "Reactome", "description": "Resolution of D-Loop Structures" }, { "id": "R-SSC-5693607", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693607", "resource": "Reactome", "description": "Processing of DNA double-strand break ends" }, { "id": "R-SSC-5696395", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696395", "resource": "Reactome", "description": "Formation of Incision Complex in GG-NER" }, { "id": "R-SSC-5696397", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696397", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in GG-NER" }, { "id": "R-SSC-5696400", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696400", "resource": "Reactome", "description": "Dual Incision in GG-NER" }, { "id": "R-SSC-6782135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782135", "resource": "Reactome", "description": "Dual incision in TC-NER" }, { "id": "R-SSC-6782210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782210", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in TC-NER" }, { "id": "R-SSC-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" }, { "id": "R-SSC-6804756", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804756", "resource": "Reactome", "description": "Regulation of TP53 Activity through Phosphorylation" }, { "id": "R-SSC-68962", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68962", "resource": "Reactome", "description": "Activation of the pre-replicative complex" }, { "id": "R-SSC-69166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69166", "resource": "Reactome", "description": "Removal of the Flap Intermediate" }, { "id": "R-SSC-69473", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69473", "resource": "Reactome", "description": "G2/M DNA damage checkpoint" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A845-1", "protein_name": "Replication protein A3", "gene_name": "Rpa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFPLIGVREICRVGEACWVSIIVRFPAGCEFWRQNHGGHNGTPQSARQRQHVITVYRTTRVLRGEAGKDGEGKNGTIELMEPLDEEISGIVEVVGKVTAKATILCASYILFKEDCNRFDLELYNEAVKIINEFPQFFPLGLTQHE", "length": 145 }, "evidence": [ { "id": "A0A4X1TNF0", "url": "https://omabrowser.org/oma/group/A0A4X1TNF0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C4C7-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGDVHEAPRPRIAAAQLVQHIGRPVCFVGRVEKIHPTGKLIVLSDGEGCNATVELSEPLDEEISGILEVVGRVTNQATIMCTSYVQFREDKSPFDLELYNEALKIIHEFPEYFPFGTGRNN", "length": 121 }, "evidence": [ { "id": "A0A4X1TNF0", "url": "https://omabrowser.org/oma/group/A0A4X1TNF0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HJH9-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "Rpa3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVDIMELPKARINASMLAQYIDRPVCFVGKLEKIHPTGKMFILSDGEGKNGTIELMEPLDEEISGVVEVVGKVTAKATIMCASYVQFKEDCVRFDLELYNEAVKIINELPQFFPLGLIQHE", "length": 121 }, "evidence": [ { "id": "A0A4X1TNF0", "url": "https://omabrowser.org/oma/group/A0A4X1TNF0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDMMDLPRSRINAGMLAQFIDKPVCFVGRLEKIHPTGKMFILSDGEGKNGTIELMEPLDEEISGIVEVVGRVTAKATILCTSYVQFKEDSHPFDLGLYNEAVKIIHDFPQFYPLGIVQHD", "length": 121 }, "evidence": [ { "id": "A0A4X1TNF0", "url": "https://omabrowser.org/oma/group/A0A4X1TNF0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQ71-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "Rpa3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDIMQLPKARVNASMLPQYIDRPVCFVGKLEKIHPTGKMFILSDGEGKNGTIELMEPLDEEISGIVEVVGKVTAKATVLCASYTLFKEDTNRFDLELYNEAVKIINELPQFFPVGLPQHE", "length": 121 }, "evidence": [ { "id": "A0A4X1TNF0", "url": "https://omabrowser.org/oma/group/A0A4X1TNF0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ], "pmid": "" }, { "name": "DNA replication factor A complex", "id": "GO:0005662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005662", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ], "pmid": "" }, { "name": "mismatch repair", "id": "GO:0006298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006298", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNF0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TNL3-1", "uniprot_ac": "A0A4X1TNL3", "uniprot_id": "A0A4X1TNL3_PIG", "mass": { "chemical_mass": 27962.0, "monoisotopic_mass": 27962.0 }, "refseq": { "ac": "XP_001927262", "name": "swi5-dependent recombination DNA repair protein 1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927262" }, "gene_names": [ { "name": "SFR1", "type": "recommended", "evidence": [ { "id": "A0A4X1TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3" } ] }, { "name": "SFR1", "type": "synonym", "evidence": [ { "id": "XP_001927262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927262" } ] } ], "protein_names": [ { "name": "Swi5-dependent recombination DNA repair protein 1 homolog", "type": "recommended", "evidence": [ { "id": "A0A4X1TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3/entry#names_and_taxonomy" } ] }, { "name": "Meiosis protein 5 homolog", "type": "synonym", "evidence": [ { "id": "A0A4X1TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3/entry#names_and_taxonomy" } ] }, { "name": "swi5-dependent recombination DNA repair protein 1 homolog", "type": "synonym", "evidence": [ { "id": "XP_001927262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927262" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SFR1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3", "locus": { "chromosome": "14", "start_pos": 115073855, "end_pos": 115065057, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010608", "url": "https://www.ensembl.org/id/ENSSSCG00000010608" } ] } } ], "crossref": [ { "id": "A0A4X1TNL3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TNL3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100157025", "url": "https://www.ncbi.nlm.nih.gov/gene/100157025", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157025", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157025", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TNL3", "url": "https://www.orthodb.org/?gene=A0A4X1TNL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28643", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28643", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28643:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28643:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10376", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10376", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001927262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927262", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TNL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TNL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGEVNQDFKMGSPDSAVILPSTPQAGANPPSPPTSSTRKQPMSATLRERLRKTRSSFNSCYSVVKRLKVESEENDQTFSEKPASSAEEKNCLEFQENFKHIDSEFEESPYSKNTFKNISACESNSFDTESCRDLQDDFMNENLPKQGLNKEKAKLVKQIQEKEDLLRRLKLVKMYRSKNDLSQLQLLIKKWRSCSQLLLYELQSAMSEENKKLSLTQLIDHYGLDDKLLHYSRNEEEFIDV", "length": 243, "header": "tr|A0A4X1TNL3-1|A0A4X1TNL3_PIG Isoform 1 of Swi5-dependent recombination DNA repair protein 1 homolog OS=Sus scrofa OX=9823 GN=SFR1 PE=3 SV=1 CANONICAL=A0A4X1TNL3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TNL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3/entry#A0A4X1TNL3-1", "sequence": { "sequence": "MAAGEVNQDFKMGSPDSAVILPSTPQAGANPPSPPTSSTRKQPMSATLRERLRKTRSSFNSCYSVVKRLKVESEENDQTFSEKPASSAEEKNCLEFQENFKHIDSEFEESPYSKNTFKNISACESNSFDTESCRDLQDDFMNENLPKQGLNKEKAKLVKQIQEKEDLLRRLKLVKMYRSKNDLSQLQLLIKKWRSCSQLLLYELQSAMSEENKKLSLTQLIDHYGLDDKLLHYSRNEEEFIDV", "length": 243, "header": "tr|A0A4X1TNL3-1|A0A4X1TNL3_PIG Isoform 1 of Swi5-dependent recombination DNA repair protein 1 homolog OS=Sus scrofa OX=9823 GN=SFR1 PE=3 SV=1 CANONICAL=A0A4X1TNL3-1" }, "locus": { "chromosome": "14", "start_pos": 115068378, "end_pos": 115065095, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011604.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011604.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011302.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011302.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157025", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157025", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3" } ], "pmid": "" }, { "name": "Swi5-Sfr1 complex", "id": "GO:0032798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032798", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNL3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TNP1-1", "uniprot_ac": "A0A4X1TNP1", "uniprot_id": "A0A4X1TNP1_PIG", "mass": { "chemical_mass": 63102.0, "monoisotopic_mass": 63102.0 }, "refseq": { "ac": "XP_003483749", "name": "solute carrier family 40 member 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483749" }, "gene_names": [ { "name": "SLC40A1", "type": "recommended", "evidence": [ { "id": "A0A4X1TNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1" } ] }, { "name": "SLC40A1", "type": "synonym", "evidence": [ { "id": "XP_003483749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483749" } ] } ], "protein_names": [ { "name": "Solute carrier family 40 member", "type": "recommended", "evidence": [ { "id": "A0A4X1TNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 40 member 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003483749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483749" } ] } ], "function": [ { "annotation": "May be involved in iron transport and iron homeostasis.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1#function" }, { "database": "UniProtKB", "id": "RU365065", "url": "https://www.uniprot.org/uniprotkb/RU365065#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC40A1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1", "locus": { "chromosome": "15", "start_pos": 94141988, "end_pos": 94167408, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027157", "url": "https://www.ensembl.org/id/ENSSSCG00000027157" } ] } } ], "crossref": [ { "id": "A0A4X1TNP1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TNP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17480", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17480", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737517", "url": "https://www.ncbi.nlm.nih.gov/gene/100737517", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737517", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737517", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TNP1", "url": "https://www.orthodb.org/?gene=A0A4X1TNP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11660", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11660", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11660:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11660:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06963", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06963", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-425410", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-425410", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-917937", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917937", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003483749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483749", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TNP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TNP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRAREQNRQGGCCGSLANYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVIQNVSVILCGIILMMVFLHKDELLTMYHGWVLTSCYILIITIANIANLASTATTITIQRDWIVVVAGEDRSKLADMNATIRRIDQLTNILAPMAVGQIMTFGSAVIGCGFISGWNLVSMCVEYFLLWKVYQKTPALAVKAVPKVEETELKQLNLYKETEPKPLEGTHLMGEKDPDIHELENEQEPSCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAVTGIMGTVAFTWLRRKCGLVRTGLISGFAQFSCLILCVISVFMPGSPLDLSVSPFENIHSRFIQTEPLSITPTKIPGLISTTDMYMSNGSDSASIVPEMSPKPVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQKTLGSRLLVCGPNDKEVTDEHQTNTSVV", "length": 575, "header": "tr|A0A4X1TNP1-1|A0A4X1TNP1_PIG Isoform 1 of Solute carrier family 40 member OS=Sus scrofa OX=9823 GN=SLC40A1 PE=3 SV=1 CANONICAL=A0A4X1TNP1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TNP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1/entry#A0A4X1TNP1-1", "sequence": { "sequence": "MTRAREQNRQGGCCGSLANYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVIQNVSVILCGIILMMVFLHKDELLTMYHGWVLTSCYILIITIANIANLASTATTITIQRDWIVVVAGEDRSKLADMNATIRRIDQLTNILAPMAVGQIMTFGSAVIGCGFISGWNLVSMCVEYFLLWKVYQKTPALAVKAVPKVEETELKQLNLYKETEPKPLEGTHLMGEKDPDIHELENEQEPSCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAVTGIMGTVAFTWLRRKCGLVRTGLISGFAQFSCLILCVISVFMPGSPLDLSVSPFENIHSRFIQTEPLSITPTKIPGLISTTDMYMSNGSDSASIVPEMSPKPVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQKTLGSRLLVCGPNDKEVTDEHQTNTSVV", "length": 575, "header": "tr|A0A4X1TNP1-1|A0A4X1TNP1_PIG Isoform 1 of Solute carrier family 40 member OS=Sus scrofa OX=9823 GN=SLC40A1 PE=3 SV=1 CANONICAL=A0A4X1TNP1-1" }, "locus": { "chromosome": "15", "start_pos": 94161459, "end_pos": 94142079, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017465.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017465.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016995.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016995.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737517", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737517", "resource": "KEGG Pathway" }, { "id": "R-SSC-425410", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-425410", "resource": "Reactome", "description": "Metal ion SLC transporters" }, { "id": "R-SSC-917937", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917937", "resource": "Reactome", "description": "Iron uptake and transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "iron ion transmembrane transport", "id": "GO:0034755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034755", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1" } ], "pmid": "" }, { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1" } ], "pmid": "" }, { "name": "ferrous iron transmembrane transporter activity", "id": "GO:0015093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015093", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1" } ], "pmid": "" }, { "name": "iron ion transmembrane transporter activity", "id": "GO:0005381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005381", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 438, "end_pos": 440 }, { "start_pos": 571, "end_pos": 573 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TNZ1-1", "uniprot_ac": "A0A4X1TNZ1", "uniprot_id": "A0A4X1TNZ1_PIG", "mass": { "chemical_mass": 98500.0, "monoisotopic_mass": 98500.0 }, "refseq": { "ac": "XP_020918358", "name": "rho GTPase-activating protein 42", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918358" }, "gene_names": [ { "name": "ARHGAP42", "type": "recommended", "evidence": [ { "id": "A0A4X1TNZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1" } ] }, { "name": "ARHGAP42", "type": "synonym", "evidence": [ { "id": "XP_020918358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918358" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 42", "type": "recommended", "evidence": [ { "id": "A0A4X1TNZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1/entry#names_and_taxonomy" } ] }, { "name": "Rho GTPase-activating protein 10-like", "type": "synonym", "evidence": [ { "id": "A0A4X1TNZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 42", "type": "synonym", "evidence": [ { "id": "A0A4X1TNZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 42", "type": "synonym", "evidence": [ { "id": "XP_020918358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918358" } ] } ], "function": [ { "annotation": "May influence blood pressure by functioning as a GTPase-activating protein for RHOA in vascular smooth muscle.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1#function" }, { "database": "UniProtKB", "id": "ARBA00056973", "url": "https://www.uniprot.org/uniprotkb/ARBA00056973#function" }, { "database": "UniProtKB", "id": "A0A4X1TTS2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTS2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARHGAP42", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1", "locus": { "chromosome": "9", "start_pos": 31994581, "end_pos": 31720849, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014976", "url": "https://www.ensembl.org/id/ENSSSCG00000014976" } ] } } ], "crossref": [ { "id": "cd01249", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01249", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04374", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07634", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07634", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519555", "url": "https://www.ncbi.nlm.nih.gov/gene/100519555", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519555", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519555", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ECIGETQ", "url": "https://omabrowser.org/oma/group/ECIGETQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TNZ1", "url": "https://www.orthodb.org/?gene=A0A4X1TNZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12552", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12552", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12552:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12552:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16746", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16746", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020918358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918358", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TNZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TTS2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TTS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTS2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELIKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKDGKKKFDKESEKYYSILDKHLNLSAKKKESHLQEADTQIDREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWIKHYCTYDKGSKTFTMSVSEMKSSGKMNGLVTSSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDMDIDIELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFIVAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPSIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSASCQPREKSGGIPWIASPSPSNGQKSLGLWTTSPESSSREDATKTDVESDCQSVASVTSPGDVSPPIDLAKKGPYGLSGLKRASASSLRSISATEGNKSYSGSTQSLTSIGSKETPKVPPNPDLPPKMCSRLRLDTASSNGYQRPGSVVAAKAQLFENVGSLKPVSSGRQAKAMYSCKAEHSHELSFPQGAIFSNVYPSVEPGWLKATYEGKTGLVPENYVVFL", "length": 874, "header": "tr|A0A4X1TNZ1-1|A0A4X1TNZ1_PIG Isoform 1 of Rho GTPase-activating protein 42 OS=Sus scrofa OX=9823 GN=ARHGAP42 PE=4 SV=1 CANONICAL=A0A4X1TNZ1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TNZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1/entry#A0A4X1TNZ1-1", "sequence": { "sequence": "MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELIKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKDGKKKFDKESEKYYSILDKHLNLSAKKKESHLQEADTQIDREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWIKHYCTYDKGSKTFTMSVSEMKSSGKMNGLVTSSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDMDIDIELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFIVAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPSIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSASCQPREKSGGIPWIASPSPSNGQKSLGLWTTSPESSSREDATKTDVESDCQSVASVTSPGDVSPPIDLAKKGPYGLSGLKRASASSLRSISATEGNKSYSGSTQSLTSIGSKETPKVPPNPDLPPKMCSRLRLDTASSNGYQRPGSVVAAKAQLFENVGSLKPVSSGRQAKAMYSCKAEHSHELSFPQGAIFSNVYPSVEPGWLKATYEGKTGLVPENYVVFL", "length": 874, "header": "tr|A0A4X1TNZ1-1|A0A4X1TNZ1_PIG Isoform 1 of Rho GTPase-activating protein 42 OS=Sus scrofa OX=9823 GN=ARHGAP42 PE=4 SV=1 CANONICAL=A0A4X1TNZ1-1" }, "locus": { "chromosome": "9", "start_pos": 31994083, "end_pos": 31721350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016338.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016338.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015899.5", "url": "https://www.ensembl.org/id/ENSSSCP00000015899.5" } ] } }, { "isoform_ac": "A0A4X1TTS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1/entry#A0A4X1TTS2-1", "sequence": { "sequence": "MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELIKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKADTQIDREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWIKHYCTYDKGSKTFTMSVSEMKSSGKMNGLVTSSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDMDIDIELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFIVAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPSIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSASCQPREKSGGIPWIASPSPSNGQKSLGLWTTSPESSSREDATKTDVESDCQSVASVTSPGDVSPPIDLAKKGPYGLSGLKRASASSLRSISATEGNKSYSGSTQSLTSIGSKETPKVPPNPDLPPKMCSRLRLDTASSNGYQRPGSVVAAKAQLFENVGSLKPVSSGRQAKAMYSCKAEHSHELSFPQGAIFSNVYPSVEPGWLKATYEGKTGLVPENYVVFL", "length": 840, "header": "tr|A0A4X1TTS2-1|A0A4X1TTS2_PIG Computationally mapped isoform of Rho GTPase-activating protein 42 OS=Sus scrofa OX=9823 GN=ARHGAP42 PE=4 SV=1 CANONICAL=A0A4X1TNZ1-1" }, "locus": { "chromosome": "9", "start_pos": 31994083, "end_pos": 31721350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069713.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069713.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065493.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065493.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519555", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519555", "resource": "KEGG Pathway" }, { "id": "R-SSC-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-SSC-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-SSC-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MT43-1", "protein_name": "Rho GTPase-activating protein 42", "gene_name": "ARHGAP42", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELIKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKDGKKKFDKESEKYYSILDKHLNLSAKKKESHLQEADTQVDREHQNFYESSLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWIKHYCTYDKGSKTFTMSVSEMKSSGKMNGLVTSSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDMDIDIELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFIVAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPSIPLPQPQSRSGSRRTRAICLSSGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKPASCQPREKSTGIPWIASPSPSNGQKSLGLWTTSPESSSREDATKTDAESDCQSVTSVTSPGDASPPIDLAKKGPYGLSGLKRASASSLRSVSAAEGNKSYSGSIQSLTSIGSKETPKAAPNPDLPPKMCRRLRLDTASSNGYQRPGSVVAAKAQLFENVGSVKPVSSGRQAKAMYSCKAEHSHELSFPQGALFSNVYPSVEPGWLKATYEGKTGLVPENYVVFL", "length": 874 }, "evidence": [ { "id": "A0A4X1TNZ1", "url": "https://omabrowser.org/oma/group/A0A4X1TNZ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I6APV4-1", "protein_name": "Rho GTPase-activating protein 42", "gene_name": "Arhgap42", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELLKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKDGKKKFDKESEKYYSILDKHLNLSAKKKESHLQEADSQIGREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKAANQDYRPPSQWTMEGYLYVQEKMFLPPALGPLGFTWTKHYCTYDKGSKMFTMSVSDVKASGKMNGLVTGSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVETRGINILGLYRIGGVNSKVQKLMNTTFSPKSPPDMDIDIELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLLKVSLHSQQNLMTISNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPNIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSTSCQPREKSGGIPWIAAPSSSNGQKSLGLWTTSPESSSREDATKTDVESDCQSVASVTSPGDVSPPIDLVKKGPYGLSGLKRSSASSSLRSISAAEGNKSYSGSIQSLTSIGSKESPKATPNPELPPKMCRRLRLDTASSNGYQRPGSVVAAKAQLFENAGSLKPVSSGRQAKAMYSCKAEHSHELSFPQGAIFSNVHPSVEPGWLKATYEGRTGLVPENYVVFL", "length": 882 }, "evidence": [ { "id": "A0A4X1TNZ1", "url": "https://omabrowser.org/oma/group/A0A4X1TNZ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XYX0-1", "protein_name": "Rho GTPase-activating protein 42", "gene_name": "ARHGAP42", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGLPTLEFSDSYLDSPDFRERLKCHEIELERTNKFIKELIKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEINIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKDGKKKFDKESEKYYSILEKHLNLSAKKKESHLQDADTQIDREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLAFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWIKHYCTYDKGTKTFTMSIAETKSGGKVNGLVTSSPEIFKLKSCIRRKTDSIDKRFCFDIEVFERPGIITLQAFSESNRKLWLEAMDGKEPIYTLPAIISKKEEMFLNEAGFNFVRKCIHAVETRGITILGLYRIGGVNSKVQKLMNTIFSPKSPPDMDIDMEIWDNKTITSGLKNYLRCLSEPLMTFKLHKDFIVAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPNIPLPQPQSRSSSRRTRAICLSTGPRKPKGRYTPCLADPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKCVPSQPREKSGGIPWIASPPSSNGQKSSGLWTTSPESSSKEDATKTDMESDCQSIASVTGPENASPPIDLTKKSSYGLSGLKRSSGSSLRSIPSAEGNKSCSGSIQSLSSADTKDTPKAPLNPDLPPKMCRRLRLDTASSNGYQRPGSVVAARAQLFESAGSLKQVSSGRQAKAMYSCKAEHSHELSFPQGAIFSNVYPSVEPGWLKATYEGKTGLVPENYVVFL", "length": 874 }, "evidence": [ { "id": "A0A4X1TNZ1", "url": "https://omabrowser.org/oma/group/A0A4X1TNZ1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6NI28-1", "protein_name": "Rho GTPase-activating protein 42", "gene_name": "ARHGAP42", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELIKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKDGKKKFDKESEKYYSILEKHLNLSAKKKESHLQEADTQIDREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWIKHYCTYDKGSKTFTMSVSEMKSSGKMNGLVTSSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDIDIDIELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPSIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSASCQPREKSGGIPWIATPSSSNGQKSLGLWTTSPESSSREDATKTDAESDCQSVASVTSPGDVSPPIDLVKKEPYGLSGLKRASASSLRSISAAEGNKSYSGSIQSLTSVGSKETPKASPNPDLPPKMCRRLRLDTASSNGYQRPGSVVAAKAQLFENVGSPKPVSSGRQAKAMYSCKAEHSHELSFPQGAIFSNVYPSVEPGWLKATYEGKTGLVPENYVVFL", "length": 874 }, "evidence": [ { "id": "A0A4X1TNZ1", "url": "https://omabrowser.org/oma/group/A0A4X1TNZ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B2RQE8-1", "protein_name": "Rho GTPase-activating protein 42", "gene_name": "Arhgap42", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELLKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKADSQIGREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWTKHYCTYDKGSKMFTMSVSDVKASGKMNGLVTGSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVEMRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDMDIDIELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLLKVSLHSQQNLMTISNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPNIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSTACQPREKSGGIPWITTPSSSNGQKSQGLWTTSPESSSREDATKTDVESDCQSVASITIPGNVSPPIDLVKKGPYGLSGLKRSSASSSLRSISAAEGNKSYSGSIQSLTSIGSKESPKAIPNPELPPKMCRRLRLDTASSNGYQRPGSVVAAKAQLFENAGSPKPVSSGRQAQAMYSCKAEHSHELSFPQGAIFSNVHPSVEPGWLKATYEGRTGLVPENYVVFL", "length": 841 }, "evidence": [ { "id": "A0A4X1TNZ1", "url": "https://omabrowser.org/oma/group/A0A4X1TNZ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZM89-1", "protein_name": "Rho GTPase-activating protein 42", "gene_name": "arhgap42a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGLPALEFSDSFLDSPDFRERLKCHEIELDRTNKFIKELIKDGNMLISALKSLSAAVQKFSQSLQDFQFECIGDAETDDEINIAQSFKEFSQLLNTVEEERRRLIQNADDVLITPLEKFRKEQIGAAKEGKKKFDKETEKYYTVLEKHLSLSSRKKESLLQEADTQISKERQVFYDASLEYVFKIQEVQERKKFEFVEPLLAFLQGLFTFYHEGYELAHEFEPYKQQLQFNLQNTRNNFESTRQEVENLMRRIRSAEQDFKAPGQWTMEGFLYVQEKRPLGCTWTRHYCTYEKGTKMFTMSNSELKTGGKQNGLIMSPPEMFKLKSCIRRRTDSIDKRFCFDIEVVERHGIITLQSLSESNRRLWMEAMDGKEPIYTLPALLSKKEETFLNEAGFNFVRKCIESVEARGINTLGLYRIGGVNSKVQRLMTSVFAAKAPADLDLDPDTWDNKTITSGLKNYLRCLAEPLMTYRLHKDFIMAVKSDDQNYRVCAVHALVYKLPDKNKEMLNLLIKHLHVVSTHSQKNLMTVSNLGVIFGPTLMRSQEETVAAMMNIKFQNIVVEILIENYDKIFHQAPDPNVPLPHPQSHSQSRGGARRSKAICLSSGSRKSRGLYPPALCLADADSDTFSSSPSSTPMGSMESLSSHSSEQNSCSKTGSPSRNKHKASGSLCWTTPSPSTNGPKSPACTTSPDSSSKEDANKTDGEWEEALSTSPGDRSSPASELLHRTLGETAEDQRSLSSCSSLTSLHISEGFRSCHGSIQSLVSRSQRDSLKSLHMPDLPPKDGMRFRDDSSASNGYQRPGSV", "length": 805 }, "evidence": [ { "id": "A0A4X1TNZ1", "url": "https://omabrowser.org/oma/group/A0A4X1TNZ1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TNZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 265, "end_pos": 374, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TNZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 376, "end_pos": 572, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TNZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TNZ1" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 816, "end_pos": 874, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 430, "end_pos": 432 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 52, "end_pos": 54 }, { "start_pos": 645, "end_pos": 647 }, { "start_pos": 747, "end_pos": 749 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TP87-1", "uniprot_ac": "A0A4X1TP87", "uniprot_id": "A0A4X1TP87_PIG", "mass": { "chemical_mass": 59194.0, "monoisotopic_mass": 59194.0 }, "refseq": { "ac": "XP_001928954", "name": "dolichol kinase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928954" }, "gene_names": [ { "name": "DOLK", "type": "recommended", "evidence": [ { "id": "A0A4X1TP87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87" } ] }, { "name": "DOLK", "type": "synonym", "evidence": [ { "id": "XP_001928954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928954" } ] } ], "protein_names": [ { "name": "dolichol kinase", "type": "recommended", "evidence": [ { "id": "A0A4X1TP87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.108", "type": "synonym", "evidence": [ { "id": "A0A4X1TP87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87/entry#names_and_taxonomy" } ] }, { "name": "dolichol kinase", "type": "synonym", "evidence": [ { "id": "XP_001928954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928954" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DOLK", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87", "locus": { "chromosome": "1", "start_pos": 269257540, "end_pos": 269259156, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005666", "url": "https://www.ensembl.org/id/ENSSSCG00000005666" } ] } } ], "crossref": [ { "id": "A0A4X1TP87", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TP87", "database": "AlphaFoldDB", "categories": [] }, { "id": "100152320", "url": "https://www.ncbi.nlm.nih.gov/gene/100152320", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152320", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152320", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EIHWPGT", "url": "https://omabrowser.org/oma/group/EIHWPGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TP87", "url": "https://www.orthodb.org/?gene=A0A4X1TP87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13205:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13205:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-446199", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446199", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001928954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928954", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TP87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TP87-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRECAPPASGSGAPLSGSVLAEAAVVFIVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGSAVFQFRMSANSGLLPASVVMPLLGLVMKERCQAAGNPYFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCVISGLAGGVIIYIMKHSLSVGEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEALLVLGGISFMLNQLIKRSLTVVESQGDPLDFFLLVVVVGMVLMGIFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHRLIRRNPLLWLFQFLFQTETRVYLLAYWSLLATLACLVVLYQNAKRSSSESKKHQAPTIARKYFHFIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLVPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 538, "header": "tr|A0A4X1TP87-1|A0A4X1TP87_PIG Isoform 1 of dolichol kinase OS=Sus scrofa OX=9823 GN=DOLK PE=3 SV=1 CANONICAL=A0A4X1TP87-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TP87-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87/entry#A0A4X1TP87-1", "sequence": { "sequence": "MTRECAPPASGSGAPLSGSVLAEAAVVFIVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGSAVFQFRMSANSGLLPASVVMPLLGLVMKERCQAAGNPYFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCVISGLAGGVIIYIMKHSLSVGEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEALLVLGGISFMLNQLIKRSLTVVESQGDPLDFFLLVVVVGMVLMGIFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHRLIRRNPLLWLFQFLFQTETRVYLLAYWSLLATLACLVVLYQNAKRSSSESKKHQAPTIARKYFHFIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLVPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 538, "header": "tr|A0A4X1TP87-1|A0A4X1TP87_PIG Isoform 1 of dolichol kinase OS=Sus scrofa OX=9823 GN=DOLK PE=3 SV=1 CANONICAL=A0A4X1TP87-1" }, "locus": { "chromosome": "1", "start_pos": 269259156, "end_pos": 269257543, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006229.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006229.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006070.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006070.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152320", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152320", "resource": "KEGG Pathway" }, { "id": "R-SSC-446199", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446199", "resource": "Reactome", "description": "Synthesis of dolichyl-phosphate" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZLM6-1", "protein_name": "dolichol kinase", "gene_name": "Dolk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRQCPPQAPESGFALSGSVLAEAAVVFAVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGNAVFQFRMSANSGLLPASMVMPLLGLVMKERCLTAGNPYFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCAISGLAGGIIIYIMKHSLSVGEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTESQGDPVDFFLLVVVVGMVLMGVFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHWLIRRNPLLWLLQFLFYTETRIYLLAYWSLLATMACLVVLYQNAKRSSSESKKHKAPTITRKYFHFIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLIPRPCAQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 536 }, "evidence": [ { "id": "A0A4X1TP87", "url": "https://omabrowser.org/oma/group/A0A4X1TP87/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3IGZ1-1", "protein_name": "dolichol kinase", "gene_name": "Dolk", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTRQCPPPVAESGFPLSGSVLAEAAVVFAVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGNAVFQFRMSANSGLLPASMVMPLLGLVMKERCQTAGNPYFERFGVVVAATGMAVALFSSVLALGITRPVPTNTCAISGLAGGIIIYIMKHSLSVGEVIEVLEVLLVFVYLNMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTESQGDPVDFFLLVVVVGMVLMGVFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHWLIRRNPLLWLLQFLFYTETRIYLLAYWSLLATMACLVVLYQNAKRSSSESKKHKAPAITRKYFHFIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLIPRPCTQKDSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 536 }, "evidence": [ { "id": "A0A4X1TP87", "url": "https://omabrowser.org/oma/group/A0A4X1TP87/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q58CR4-1", "protein_name": "Dolichol kinase", "gene_name": "DOLK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTRECAPPTPGSGAPLSGSVLAEAAVVFVVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGSAVFQFRMSANSGLLPASVVMPLLGLVMKERCQAAGNPYFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCVISGLAGGVIIYIMKHSLSVGEVIEVLEALLIFVYLNMILLYLLPRCFTPGEALLVLGGISFMLNQLIKRSLTVVESQGDPLDFFLLVVVVGMVLMGIFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHRLIRRNPLLWLFQFLFQTETRVYLLAYWCLLATVACLVVLYQNAKRSSSESKKHQAPTITRKYFHFIVVATYIPGIILDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLVPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 538 }, "evidence": [ { "id": "A0A4X1TP87", "url": "https://omabrowser.org/oma/group/A0A4X1TP87/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R2Y3-1", "protein_name": "Dolichol kinase", "gene_name": "Dolk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRQCPPQESGAALSGSVLAEAAVVFAVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGNAVFQFRMSANSGLLPASMVMPLLGLVMKERCQTAGNPYFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCAISGLAGGVIIYIMRHSLSVGEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTESQGDPVDFFLLVVVVGMVLMGVFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHWLIRRNPLLWLLQFLFYTETRIYLLAYWSLLASVACLVVLYQNAKRSSSESKKHRAPTITRKYFHFIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLIPRPCTQKDSLEGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 534 }, "evidence": [ { "id": "A0A4X1TP87", "url": "https://omabrowser.org/oma/group/A0A4X1TP87/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UPQ8-1", "protein_name": "Dolichol kinase", "gene_name": "DOLK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTRECPSPAPGPGAPLSGSVLAEAAVVFAVVLSIHATVWDRYSWCAVALAVQAFYVQYKWDRLLQQGSAVFQFRMSANSGLLPASMVMPLLGLVMKERCQTAGNPFFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCVILGLAGGVIIYIMKHSLSVGEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTLVESQGDPVDFFLLVVVVGMVLMGIFFSTLFVFMDSGTWASSIFFHLMTCVLSLGVVLPWLHRLIRRNPLLWLLQFLFQTDTRIYLLAYWSLLATLACLVVLYQNAKRSSSESKKHQAPTIARKYFHLIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSFLSLFLDERDSGPLILTHIYLLLGMSLPIWLIPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 538 }, "evidence": [ { "id": "A0A4X1TP87", "url": "https://omabrowser.org/oma/group/A0A4X1TP87/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GI61-1", "protein_name": "dolichol kinase", "gene_name": "DOLK", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLNKPVLVESLIVFSIVLCVHAVVWDRYSWCAVALAIQAFYVQFKWDRLLQQGGAVFQFRTTANSGLLPASMVIPLLGIAMKERCKAAGIVYFERFGIVVASTGMLVALFLSVIAVGITKPVPTNTCILSGVAGSIIIYTMKHSLTVSEVIEVLEVLLIFVYLSMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLNVIEGRGEPIDFFLLVAVIGVVILGLFFTVLFIFMDSGTWISSMFFHMMTAVLGLGVIMPWLYRLIRRNPLFWLLQFLFQTQTRVYLLIYWTLLAASACGIVFYQNAKRSSESKKHQASTITRKYFHFIVVATYVPGLIYDRQLLHVAAVLCLAVFIFLEYIRYFRIKPFGQTLRYLLSLFLDERDSGPLILTHIYLLLGMSLPVWLFPRSCAPKGALSGAGALVPYAGVLAVGVGDTMASVFGSTMGEIKWPGTKKTFEGTMTAIFAQIIAVALILIFDSSVNLNSSYAWILVSVSLVSLLEAYTTQIDNLLLPLYLQIMFMV", "length": 523 }, "evidence": [ { "id": "A0A4X1TP87", "url": "https://omabrowser.org/oma/group/A0A4X1TP87/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dolichol kinase activity", "id": "GO:0004168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004168", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "dolichyl monophosphate biosynthetic process", "id": "GO:0043048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043048", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TP87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TP87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-449221" ], "output_participant_list": [ "R-ALL-110094" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-446195", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446195" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-110094", "participant_name": "CDP [cytosol]", "crossref": [ { "id": "ZINC000008215624", "database": "ZINC", "url": "" }, { "id": "C00112", "database": "COMPOUND", "url": "" }, { "id": "58069", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-449221", "participant_name": "DCHOL [cytoplasmic side of endoplasmic reticulum membrane]", "crossref": [ { "id": "16091", "database": "ChEBI", "url": "" }, { "id": "C00381", "database": "COMPOUND", "url": "" }, { "id": "ZINC000030320742", "database": "ZINC", "url": "" }, { "id": "ZINC000030320745", "database": "ZINC", "url": "" }, { "id": "HMDB0005176", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 500, "end_pos": 502 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TPT1-1", "uniprot_ac": "A0A4X1TPT1", "uniprot_id": "A0A4X1TPT1_PIG", "mass": { "chemical_mass": 12538.0, "monoisotopic_mass": 12538.0 }, "refseq": { "ac": "XP_003357274", "name": "60S ribosomal protein L35a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357274" }, "gene_names": [ { "name": "RPL35A", "type": "recommended", "evidence": [ { "id": "A0A4X1TPT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1" } ] }, { "name": "LOC100519675", "type": "synonym", "evidence": [ { "id": "XP_003357274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357274" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein eL33", "type": "recommended", "evidence": [ { "id": "A0A4X1TPT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L35a", "type": "synonym", "evidence": [ { "id": "XP_003357274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357274" }, { "id": "A0A4X1TPT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for the proliferation and viability of hematopoietic cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1#function" }, { "database": "UniProtKB", "id": "ARBA00045649", "url": "https://www.uniprot.org/uniprotkb/ARBA00045649#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPL35A", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1", "locus": { "chromosome": "13", "start_pos": 134591868, "end_pos": 134588392, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040273", "url": "https://www.ensembl.org/id/ENSSSCG00000040273" } ] } } ], "crossref": [ { "id": "A0A4X1TPT1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TPT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100514796", "url": "https://www.ncbi.nlm.nih.gov/gene/100514796", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "100519675", "url": "https://www.ncbi.nlm.nih.gov/gene/100519675", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514796", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514796", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ssc:100519675", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519675", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YRTNKHH", "url": "https://omabrowser.org/oma/group/YRTNKHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TPT1", "url": "https://www.orthodb.org/?gene=A0A4X1TPT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01247", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01247", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003357274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TPT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TPT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGRLWSKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRVIWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "length": 110, "header": "tr|A0A4X1TPT1-1|A0A4X1TPT1_PIG Isoform 1 of Large ribosomal subunit protein eL33 OS=Sus scrofa OX=9823 GN=RPL35A PE=1 SV=1 CANONICAL=A0A4X1TPT1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TPT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1/entry#A0A4X1TPT1-1", "sequence": { "sequence": "MSGRLWSKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRVIWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "length": 110, "header": "tr|A0A4X1TPT1-1|A0A4X1TPT1_PIG Isoform 1 of Large ribosomal subunit protein eL33 OS=Sus scrofa OX=9823 GN=RPL35A PE=1 SV=1 CANONICAL=A0A4X1TPT1-1" }, "locus": { "chromosome": "13", "start_pos": 134591818, "end_pos": 134589014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044369.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044369.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032320.1", "url": "https://www.ensembl.org/id/ENSSSCP00000032320.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 59, "start_aa": "Thr", "end_pos": 59, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr59", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514796", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514796", "resource": "KEGG Pathway" }, { "id": "ssc:100519675", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519675", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8L2QJQ6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "Rpl35al11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGRLWCKAIFAGYKPGLLNQREYTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRVIWGKVTRAHGNSGVVRAKFQSNLPAKAIGHRIRVMLYPSQI", "length": 110 }, "evidence": [ { "id": "A0A4X1TPT1", "url": "https://omabrowser.org/oma/group/A0A4X1TPT1/", "database": "OMA" }, { "id": "A0A4X1TPT1", "url": "https://omabrowser.org/oma/group/A0A4X1TPT1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O55142-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "Rpl35a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRVIWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A4X1TPT1", "url": "https://omabrowser.org/oma/group/A0A4X1TPT1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04646-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "Rpl35a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRVIWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A4X1TPT1", "url": "https://omabrowser.org/oma/group/A0A4X1TPT1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05744-1", "protein_name": "Large ribosomal subunit protein eL33A", "gene_name": "RPL33A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAESHRLYVKGKHLSYQRSKRVNNPNVSLIKIEGVATPQDAQFYLGKRIAYVYRASKEVRGSKIRVMWGKVTRTHGNSGVVRATFRNNLPAKTFGASVRIFLYPSNI", "length": 107 }, "evidence": [ { "id": "A0A4X1TPT1", "url": "https://omabrowser.org/oma/group/A0A4X1TPT1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P18077-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "RPL35A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGRLWSKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRVIWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A4X1TPT1", "url": "https://omabrowser.org/oma/group/A0A4X1TPT1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55BN7-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "rpl35a", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKIYSKGVVLGYRRSQATQYPNISLIKIEGVVSREDSTFYLGKKVCLVSKVSKSAKNPTGHKISWGKICKTHGSSGVVQARFARNLPPKAMGAPVRVMLYPSNI", "length": 105 }, "evidence": [ { "id": "A0A4X1TPT1", "url": "https://omabrowser.org/oma/group/A0A4X1TPT1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q56JY1-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "RPL35A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGRLWSKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRVIWGKITRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A4X1TPT1", "url": "https://omabrowser.org/oma/group/A0A4X1TPT1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9C912-1", "protein_name": "Large ribosomal subunit protein eL33y", "gene_name": "RPL35AC", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVKGRQGERVRLYVRGTILGYKRSKSNQYPNTSLVQIEGVNTQEEVNWYKGKRMAYIYKAKTKKNGSHYRCIWGKVTRPHGNSGVVRAKFTSNLPPKSMGSRVRVFMYPSNI", "length": 112 }, "evidence": [ { "id": "A0A4X1TPT1", "url": "https://omabrowser.org/oma/group/A0A4X1TPT1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FZH0-1", "protein_name": "Large ribosomal subunit protein eL33z", "gene_name": "RPL35AB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKGRQGERVRLYVRGTVLGYKRSKSNQYPNTSLIQIEGVNTQEEVNWYKGKRLAYIYKAKTKKNGSHYRCIWGKVTRPHGNSGVVRSKFTSNLPPKSMGARVRVFMYPSNI", "length": 111 }, "evidence": [ { "id": "A0A4X1TPT1", "url": "https://omabrowser.org/oma/group/A0A4X1TPT1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VNB9-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "RpL35A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MADTQAKSTTAPKAAKAQKAPKAVKAPKAEKPAASEAKVSAKKYKRHGRLFAKAVFTGYKRGLRNQHENQAILKIEGARRKEHGSFYVGKRCVYVYKAETKKCVPQHPERKTRVRAVWGKVTRIHGNTGAVRARFNRNLPGHAMGHRIRIMLYPSRI", "length": 157 }, "evidence": [ { "id": "A0A4X1TPT1", "url": "https://omabrowser.org/oma/group/A0A4X1TPT1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 59 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 55, "end_pos": 57 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TPU0-1", "uniprot_ac": "A0A4X1TPU0", "uniprot_id": "A0A4X1TPU0_PIG", "mass": { "chemical_mass": 14972.0, "monoisotopic_mass": 14972.0 }, "refseq": { "ac": "NP_001230449", "name": "phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230449" }, "gene_names": [ { "name": "PIGP", "type": "recommended", "evidence": [ { "id": "A0A4X1TPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0" } ] }, { "name": "PIGP", "type": "synonym", "evidence": [ { "id": "NP_001230449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230449" } ] } ], "protein_names": [ { "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "type": "recommended", "evidence": [ { "id": "A0A4X1TPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0/entry#names_and_taxonomy" } ] }, { "name": "phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "type": "synonym", "evidence": [ { "id": "NP_001230449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230449" } ] } ], "function": [ { "annotation": "Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0#function" }, { "database": "UniProtKB", "id": "PIRNR008765", "url": "https://www.uniprot.org/uniprotkb/PIRNR008765#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PIGP", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0", "locus": { "chromosome": "13", "start_pos": 200686666, "end_pos": 200695320, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012061", "url": "https://www.ensembl.org/id/ENSSSCG00000012061" } ] } } ], "crossref": [ { "id": "A0A4X1TPU0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TPU0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012061", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012061", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100154885", "url": "https://www.ncbi.nlm.nih.gov/gene/100154885", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154885", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154885", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KGICNRN", "url": "https://omabrowser.org/oma/group/KGICNRN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TPU0", "url": "https://www.orthodb.org/?gene=A0A4X1TPU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46346:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46346:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08510", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08510", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-162710", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-162710", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230449", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230449", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TPU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TPU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0K9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVENSPSPLPERAIYGFVLFLSSQFGFMLYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLITIVIGYVLLFGINMMSTSPLNSIHTITDNYAKNQQQKKYQEEAIPALRDIPISEVNQMFFLTAKKP", "length": 130, "header": "tr|A0A4X1TPU0-1|A0A4X1TPU0_PIG Isoform 1 of Phosphatidylinositol N-acetylglucosaminyltransferase subunit P OS=Sus scrofa OX=9823 GN=PIGP PE=3 SV=1 CANONICAL=A0A4X1TPU0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TPU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0/entry#A0A4X1TPU0-1", "sequence": { "sequence": "MVENSPSPLPERAIYGFVLFLSSQFGFMLYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLITIVIGYVLLFGINMMSTSPLNSIHTITDNYAKNQQQKKYQEEAIPALRDIPISEVNQMFFLTAKKP", "length": 130, "header": "tr|A0A4X1TPU0-1|A0A4X1TPU0_PIG Isoform 1 of Phosphatidylinositol N-acetylglucosaminyltransferase subunit P OS=Sus scrofa OX=9823 GN=PIGP PE=3 SV=1 CANONICAL=A0A4X1TPU0-1" }, "locus": { "chromosome": "13", "start_pos": 200694832, "end_pos": 200686816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044360.1", "url": "https://www.ensembl.org/id/ENSSSCT00000044360.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049910.1", "url": "https://www.ensembl.org/id/ENSSSCP00000049910.1" } ] } }, { "isoform_ac": "A0A5G2R0K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0/entry#A0A5G2R0K9-1", "sequence": { "sequence": "MMLYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLITIVIGYVLLFGINMMSTSPLNSIHTITDNYAKNQQQKKYQEEAIPALRDIPISEVNQMFFLTAKKP", "length": 104, "header": "tr|A0A5G2R0K9-1|A0A4X1TPU0_PIG Computationally mapped isoform of Phosphatidylinositol N-acetylglucosaminyltransferase subunit P OS=Sus scrofa OX=9823 GN=PIGP PE=3 SV=1 CANONICAL=A0A4X1TPU0-1" }, "locus": { "chromosome": "13", "start_pos": 200694465, "end_pos": 200686816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085110.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085110.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070690.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070690.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0K9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0K9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154885", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154885", "resource": "KEGG Pathway" }, { "id": "R-SSC-162710", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-162710", "resource": "Reactome", "description": "Synthesis of glycosylphosphatidylinositol (GPI)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LBB8-1", "protein_name": "Phosphatidylinositol glycan anchor biosynthesis, class P", "gene_name": "Pigp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAIKHPAITSVSHRLVTGISTYCGNNLQTEGCLETTSFWKRHRAGVPAHPRLHFGPLRPPRLSPPHYGMAAQALMTSPALLSSSPCAGVGQGCRLSKATGKMVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFVPESWLNSLGLTYWPQKYWAVALPVYLLITVVIGYVLLFGINMMSTSPLDSIHTITDNYAKNQQRKSYQEDAIPALRDIPISEVNRMFFLDAKELNT", "length": 234 }, "evidence": [ { "id": "A0A4X1TPU0", "url": "https://omabrowser.org/oma/group/A0A4X1TPU0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B3H5S3-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase, GPI19/PIG-P subunit", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSPAKVSSFDQNIEEAHSVSSPRRVLSFSKRNKQKPGFQDTDSRRSSSFRASEVHGPKPSEVYGFVGSISTVVATVIFLVWAYVPDKLLESIGIHYYPSRYWVLAMPTYLMVTLMLALAFYIGLNFIATPPPTSLNTLFDEYSREPGEFAAGMEEGEDRPIDPISDIDITRINDLMFNSSD", "length": 181 }, "evidence": [ { "id": "A0A4X1TPU0", "url": "https://omabrowser.org/oma/group/A0A4X1TPU0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P57054-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "gene_name": "PIGP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVPRSTSLTLIVFLFHRLSKAPGKMVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAIVIGYVLLFGINMMSTSPLDSIHTITDNYAKNQQQKKYQEEAIPALRDISISEVNQMFFLAAKELYTKN", "length": 158 }, "evidence": [ { "id": "A0A4X1TPU0", "url": "https://omabrowser.org/oma/group/A0A4X1TPU0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JHG1-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "gene_name": "Pigp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFVPESWLNSLGLTYWPQKYWAVALPVYLLITVVIGYVLLFGINMMSTSPLDSIHTITDNYAKNQQRKNYQEDAIPALRDVPISEVNKMFFLGAKELNT", "length": 132 }, "evidence": [ { "id": "A0A4X1TPU0", "url": "https://omabrowser.org/oma/group/A0A4X1TPU0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex", "id": "GO:0000506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000506", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol N-acetylglucosaminyltransferase activity", "id": "GO:0017176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017176", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TPU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TPU0" }, { "id": "PF08510", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08510" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIG-P", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 124, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TQB7-1", "uniprot_ac": "A0A4X1TQB7", "uniprot_id": "A0A4X1TQB7_PIG", "mass": { "chemical_mass": 23865.0, "monoisotopic_mass": 23865.0 }, "refseq": { "ac": "XP_020928460", "name": "sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928460" }, "gene_names": [ { "name": "NKAIN2", "type": "recommended", "evidence": [ { "id": "A0A4X1TQB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQB7" } ] }, { "name": "NKAIN2", "type": "synonym", "evidence": [ { "id": "XP_020928460", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928460" } ] } ], "protein_names": [ { "name": "Sodium/potassium-transporting ATPase subunit beta-1-interacting protein", "type": "recommended", "evidence": [ { "id": "A0A4X1TQB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQB7/entry#names_and_taxonomy" } ] }, { "name": "Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A4X1TQB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQB7/entry#names_and_taxonomy" } ] }, { "name": "sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_020928460", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928460" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TQB7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQB7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NKAIN2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQB7", "locus": { "chromosome": "1", "start_pos": 38014255, "end_pos": 39040605, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036607", "url": "https://www.ensembl.org/id/ENSSSCG00000036607" } ] } } ], "crossref": [ { "id": "A0A4X1TQB7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TQB7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000036607", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036607", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100624679", "url": "https://www.ncbi.nlm.nih.gov/gene/100624679", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13084", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13084", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13084:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13084:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020928460", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928460", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TQB7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TQB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1V0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGYCSGRCTLIFICGMQLVCVLERQIFDFLGYQWAPILANFVHIIIVILGLFGTIQYRPRYITGYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCFLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYMSK", "length": 208, "header": "tr|A0A4X1TQB7-1|A0A4X1TQB7_PIG Isoform 1 of Sodium/potassium-transporting ATPase subunit beta-1-interacting protein OS=Sus scrofa OX=9823 GN=NKAIN2 PE=3 SV=1 CANONICAL=A0A4X1TQB7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TQB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQB7/entry#A0A4X1TQB7-1", "sequence": { "sequence": "MGYCSGRCTLIFICGMQLVCVLERQIFDFLGYQWAPILANFVHIIIVILGLFGTIQYRPRYITGYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCFLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYMSK", "length": 208, "header": "tr|A0A4X1TQB7-1|A0A4X1TQB7_PIG Isoform 1 of Sodium/potassium-transporting ATPase subunit beta-1-interacting protein OS=Sus scrofa OX=9823 GN=NKAIN2 PE=3 SV=1 CANONICAL=A0A4X1TQB7-1" }, "locus": { "chromosome": "1", "start_pos": 39039841, "end_pos": 38016556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086190.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086190.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069048.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069048.1" } ] } }, { "isoform_ac": "A0A5G2R1V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQB7/entry#A0A5G2R1V0-1", "sequence": { "sequence": "MGYCSGRCTLIFICGMQLVCVLERQIFDFLGYQWAPILANFVHIIIVILGLFGTIQYRPRYITGYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCFLEYQYIEVAHSSLQIVLAVSFDSQPLHLVLLLFCLYANAVHTVGTYGQ", "length": 188, "header": "tr|A0A5G2R1V0-1|A0A4X1TQB7_PIG Computationally mapped isoform of Sodium/potassium-transporting ATPase subunit beta-1-interacting protein OS=Sus scrofa OX=9823 GN=NKAIN2 PE=3 SV=1 CANONICAL=A0A4X1TQB7-1" }, "locus": { "chromosome": "1", "start_pos": 39039841, "end_pos": 38158690, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086076.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086076.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070325.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070325.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 121, "start_aa": "Thr", "end_pos": 121, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr121", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R1V0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1V0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TQB7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of sodium ion transport", "id": "GO:0002028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002028", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TQB7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 121 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TQP6-1", "uniprot_ac": "A0A4X1TQP6", "uniprot_id": "A0A4X1TQP6_PIG", "mass": { "chemical_mass": 48435.0, "monoisotopic_mass": 48435.0 }, "refseq": { "ac": "XP_020926634", "name": "G protein-activated inward rectifier potassium channel 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926634" }, "gene_names": [ { "name": "KCNJ6", "type": "recommended", "evidence": [ { "id": "A0A4X1TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6" } ] }, { "name": "KCNJ6", "type": "synonym", "evidence": [ { "id": "XP_020926634", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926634" } ] } ], "protein_names": [ { "name": "G protein-activated inward rectifier potassium channel 2", "type": "recommended", "evidence": [ { "id": "A0A4X1TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6/entry#names_and_taxonomy" } ] }, { "name": "Cardiac inward rectifier", "type": "synonym", "evidence": [ { "id": "A0A4X1TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6/entry#names_and_taxonomy" } ] }, { "name": "G protein-activated inward rectifier potassium channel 2", "type": "synonym", "evidence": [ { "id": "XP_020926634", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926634" } ] }, { "name": "G protein-activated inward rectifier potassium channel 4", "type": "synonym", "evidence": [ { "id": "A0A4X1TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6/entry#names_and_taxonomy" } ] }, { "name": "Heart KATP channel", "type": "synonym", "evidence": [ { "id": "A0A4X1TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6/entry#names_and_taxonomy" } ] }, { "name": "Inward rectifier K(+) channel Kir3.4", "type": "synonym", "evidence": [ { "id": "A0A4X1TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6/entry#names_and_taxonomy" } ] }, { "name": "KATP-1", "type": "synonym", "evidence": [ { "id": "A0A4X1TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6/entry#names_and_taxonomy" } ] }, { "name": "Potassium channel, inwardly rectifying subfamily J member 5", "type": "synonym", "evidence": [ { "id": "A0A4X1TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6/entry#names_and_taxonomy" } ] }, { "name": "Potassium channel, inwardly rectifying subfamily J member 6", "type": "synonym", "evidence": [ { "id": "A0A4X1TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TQP6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KCNJ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6", "locus": { "chromosome": "13", "start_pos": 201243609, "end_pos": 201525820, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012065", "url": "https://www.ensembl.org/id/ENSSSCG00000012065" } ] } } ], "crossref": [ { "id": "A0A4X1TQP6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TQP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100515928", "url": "https://www.ncbi.nlm.nih.gov/gene/100515928", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515928", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515928", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TQP6", "url": "https://www.orthodb.org/?gene=A0A4X1TQP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01007", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01007", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17655", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17655", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1296041", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296041", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-997272", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020926634", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926634", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TQP6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TQP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNPEEQTERNGDVANLENESKV", "length": 423, "header": "tr|A0A4X1TQP6-1|A0A4X1TQP6_PIG Isoform 1 of G protein-activated inward rectifier potassium channel 2 OS=Sus scrofa OX=9823 GN=KCNJ6 PE=3 SV=1 CANONICAL=A0A4X1TQP6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TQP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6/entry#A0A4X1TQP6-1", "sequence": { "sequence": "MAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNPEEQTERNGDVANLENESKV", "length": 423, "header": "tr|A0A4X1TQP6-1|A0A4X1TQP6_PIG Isoform 1 of G protein-activated inward rectifier potassium channel 2 OS=Sus scrofa OX=9823 GN=KCNJ6 PE=3 SV=1 CANONICAL=A0A4X1TQP6-1" }, "locus": { "chromosome": "13", "start_pos": 201447346, "end_pos": 201248376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064153.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064153.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057704.3", "url": "https://www.ensembl.org/id/ENSSSCP00000057704.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TQP6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515928", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515928", "resource": "KEGG Pathway" }, { "id": "R-SSC-1296041", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296041", "resource": "Reactome", "description": "Activation of G protein gated Potassium channels" }, { "id": "R-SSC-997272", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "resource": "Reactome", "description": "Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G-protein activated inward rectifier potassium channel activity", "id": "GO:0015467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015467", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TQP6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TQP6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6" } ], "pmid": "" }, { "name": "I(KACh) inward rectifier potassium channel complex", "id": "GO:1990566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990566", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TQP6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion import across plasma membrane", "id": "GO:1990573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990573", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TQP6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6" }, { "id": "PF17655", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17655" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Inward rectifier potassium channel C-terminal", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 372, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TQP6" }, { "id": "PF01007", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01007" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel inwardly rectifying transmembrane", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 196, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 419, "end_pos": 421 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A5G2RKL2-1", "uniprot_ac": "A0A5G2RKL2", "uniprot_id": "A0A5G2RKL2_PIG", "mass": { "chemical_mass": 10750.0, "monoisotopic_mass": 10750.0 }, "refseq": {}, "gene_names": [ { "name": "ACYP2", "type": "recommended", "evidence": [ { "id": "A0A5G2RKL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2" } ] } ], "protein_names": [ { "name": "Acylphosphatase-2", "type": "recommended", "evidence": [ { "id": "A0A5G2RKL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2/entry#names_and_taxonomy" } ] }, { "name": "3.6.1.7", "type": "synonym", "evidence": [ { "id": "A0A5G2RKL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2/entry#names_and_taxonomy" } ] }, { "name": "Acylphosphatase, muscle type isozyme", "type": "synonym", "evidence": [ { "id": "A0A5G2RKL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2/entry#names_and_taxonomy" } ] }, { "name": "Acylphosphate phosphohydrolase 2", "type": "synonym", "evidence": [ { "id": "A0A5G2RKL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ACYP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2", "locus": { "chromosome": "3", "start_pos": 86945647, "end_pos": 87109139, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000025224", "url": "https://www.ensembl.org/id/ENSSSCG00000025224" } ] } } ], "crossref": [ { "id": "A0A5G2RKL2", "url": "https://alphafold.ebi.ac.uk/entry/A0A5G2RKL2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000025224", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000025224", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100516794", "url": "https://www.ncbi.nlm.nih.gov/gene/100516794", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001792", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001792", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516794", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516794", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HAIMAEN", "url": "https://omabrowser.org/oma/group/HAIMAEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1W6M0", "url": "https://www.orthodb.org/?gene=A0A4X1W6M0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10029", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10029", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10029:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10029:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00708", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00708", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "14965", "url": "https://www.rhea-db.org/rhea/14965", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1W6M0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W6M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1W6M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W6M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1WCB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1WCB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1WCB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1WCB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTARPLKSVDYEVFGRVQGRGFTNNEARKIGVVGWVKNTSKGTVTGQVQGPEEKVNSMKSWLSKIGSPSSRIDRTNFSNEKTISKLEYSNFSIRY", "length": 96, "header": "tr|A0A5G2RKL2-1|A0A5G2RKL2_PIG Isoform 1 of Acylphosphatase-2 OS=Sus scrofa OX=9823 GN=ACYP2 PE=3 SV=2 CANONICAL=A0A5G2RKL2-1" }, "isoforms": [ { "isoform_ac": "A0A4X1W6M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2/entry#A0A4X1W6M0-1", "sequence": { "sequence": "MCPFPLAAAAVAAPRTPLRLLGRRLAAAMSTARPLKSVDYEVFGRVQGVCFRMYTEDEARKIGVVGWVKNTSKGTVTGQVQGPEEKVNSMKSWLSKIGSPSSRIDRTNFSNEKTISKLEYSNFSIRY", "length": 127, "header": "tr|A0A4X1W6M0-1|A0A4X1W6M0_PIG Computationally mapped isoform of Acylphosphatase OS=Sus scrofa OX=9823 GN=ACYP2 PE=3 SV=1 CANONICAL=A0A5G2RKL2-1" }, "locus": { "chromosome": "3", "start_pos": 87108966, "end_pos": 86946000, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030730.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030730.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021583.2", "url": "https://www.ensembl.org/id/ENSSSCP00000021583.2" } ] } }, { "isoform_ac": "A0A4X1WCB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2/entry#A0A4X1WCB2-1", "sequence": { "sequence": "MCPFPLAAAAVAAPRTPLRLLGRRLAAAMSTARPLKSVDYEVFGRVQGVCFRMYTEDEARKIGVVGWVKNTSKGTVTGQVQGPEEKVNSMDLLSPEAWV", "length": 99, "header": "tr|A0A4X1WCB2-1|A0A4X1WCB2_PIG Computationally mapped isoform of Acylphosphatase OS=Sus scrofa OX=9823 GN=ACYP2 PE=3 SV=1 CANONICAL=A0A5G2RKL2-1" }, "locus": { "chromosome": "3", "start_pos": 87108966, "end_pos": 86984966, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076001.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076001.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067933.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067933.1" } ] } }, { "isoform_ac": "A0A5G2RKL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2/entry#A0A5G2RKL2-1", "sequence": { "sequence": "MSTARPLKSVDYEVFGRVQGRGFTNNEARKIGVVGWVKNTSKGTVTGQVQGPEEKVNSMKSWLSKIGSPSSRIDRTNFSNEKTISKLEYSNFSIRY", "length": 96, "header": "tr|A0A5G2RKL2-1|A0A5G2RKL2_PIG Isoform 1 of Acylphosphatase-2 OS=Sus scrofa OX=9823 GN=ACYP2 PE=3 SV=2 CANONICAL=A0A5G2RKL2-1" }, "locus": { "chromosome": "3", "start_pos": 87108882, "end_pos": 86946000, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084997.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084997.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072677.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072677.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516794", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516794", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P07031-1", "protein_name": "Acylphosphatase-2", "gene_name": "ACYP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSALTKASGSLKSVDYEVFGRVQGVCFRMYTEEEARKLGVVGWVKNTSQGTVTGQVQGPEDKVNAMKSWLSKVGSPSSRIDRTKFSNEKEISKLDFSGFSTRY", "length": 103 }, "evidence": [ { "id": "A0A5G2RKL2", "url": "https://omabrowser.org/oma/group/A0A5G2RKL2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P07033-1", "protein_name": "Acylphosphatase-2", "gene_name": "ACYP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSTGRPLKSVDYEVFGRVQGVCFRMYTEDEARKIGVVGWVKNTSKGTVTGQVQGPEEKVNSMKSWLSKVGSPSSRIDRTNFSNEKTISKLEYSSFNIRY", "length": 99 }, "evidence": [ { "id": "A0A5G2RKL2", "url": "https://omabrowser.org/oma/group/A0A5G2RKL2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P14621-1", "protein_name": "Acylphosphatase-2", "gene_name": "ACYP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTAQSLKSVDYEVFGRVQGVCFRMYTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKVGSPSSRIDRTNFSNEKTISKLEYSNFSIRY", "length": 99 }, "evidence": [ { "id": "A0A5G2RKL2", "url": "https://omabrowser.org/oma/group/A0A5G2RKL2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35745-1", "protein_name": "Acylphosphatase-2", "gene_name": "Acyp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEPLKSVDYEVFGTVQGVCFRMYTEGEAKKRGLVGWVKNTSKGTVTGQVQGPEEKVNSMKSWLSKVGSPSSRIDRADFSNEKTISKLEYSNFSIRY", "length": 97 }, "evidence": [ { "id": "A0A5G2RKL2", "url": "https://omabrowser.org/oma/group/A0A5G2RKL2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56375-1", "protein_name": "Acylphosphatase-2", "gene_name": "Acyp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLGRRLAAMTELLKSVDYEVFGTVQGVCFRMYTEGEAKKRGLVGWVKNTSKGTVTGQVQGPEEKVDAMKSWLSKVGSPSSRIDRADFSNEKTISKLEYSDFSIRY", "length": 106 }, "evidence": [ { "id": "A0A5G2RKL2", "url": "https://omabrowser.org/oma/group/A0A5G2RKL2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56544-1", "protein_name": "Acylphosphatase-1", "gene_name": "Acyp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATHNVHSCEFEVFGRVQGVNFRRHALRKAKTLGLRGWCMNSSRGTVKGYIEGRPAEMDVMKEWLRTTGSPLSSIEKVEFSSQRERDRYGYANFHIKPDPHENRPVHEGLGSSSSHHDSN", "length": 120 }, "evidence": [ { "id": "A0A5G2RKL2", "url": "https://omabrowser.org/oma/group/A0A5G2RKL2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2" } ], "pmid": "" }, { "name": "acylphosphatase activity", "id": "GO:0003998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003998", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RKL2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14965", "name": "", "equation": "an acyl phosphate + H2O = a carboxylate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "14965", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14965" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A5G2RKL2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 96, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A5G2RKL2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A5G2RKL2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A5G2RKL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKL2" }, { "id": "PS51160", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51160" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Acylphosphatase-like", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 96, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 39, "end_pos": 41 }, { "start_pos": 77, "end_pos": 79 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VSD8-1", "uniprot_ac": "A0A4X1VSD8", "uniprot_id": "A0A4X1VSD8_PIG", "mass": { "chemical_mass": 45129.0, "monoisotopic_mass": 45129.0 }, "refseq": {}, "gene_names": [ { "name": "OPRM1", "type": "recommended", "evidence": [ { "id": "A0A4X1VSD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ] } ], "protein_names": [ { "name": "Mu-type opioid receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1VSD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OPRM1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8", "locus": { "chromosome": "1", "start_pos": 12528672, "end_pos": 12702443, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004074", "url": "https://www.ensembl.org/id/ENSSSCG00000004074" } ] } } ], "crossref": [ { "id": "A0A4X1VSD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1VSD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004074", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004074", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15090", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15090", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24229:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24229:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-111885", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-202040", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202040", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A116", "url": "https://www.uniprot.org/uniprotkb/A0A287A116", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A116-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A116-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VSD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S7X7", "url": "https://www.uniprot.org/uniprotkb/F1S7X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S7X7-1", "url": "https://www.uniprot.org/uniprotkb/F1S7X7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSSADPRNASNCTDPFSPSSMCSPVPSPSSWVNFSHLEGNLSDPCIRNRTELGGSDSLCPPTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRNGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP", "length": 401, "header": "tr|A0A4X1VSD8-1|A0A4X1VSD8_PIG Isoform 1 of Mu-type opioid receptor OS=Sus scrofa OX=9823 GN=OPRM1 PE=3 SV=1 CANONICAL=A0A4X1VSD8-1" }, "isoforms": [ { "isoform_ac": "A0A287A116-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8/entry#A0A287A116-1", "sequence": { "sequence": "MDSSADPRNASNCTDPFSPSSMCSPVPSPSSWVNFSHLEGNLSDPCIRNRTELGGSDSLCPPTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRNGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTRDHPSTANTVDRTNHQVHRRKEAESKL", "length": 400, "header": "tr|A0A287A116-1|A0A4X1VSD8_PIG Computationally mapped isoform of Mu-type opioid receptor OS=Sus scrofa OX=9823 GN=OPRM1 PE=3 SV=2 CANONICAL=A0A4X1VSD8-1" }, "locus": { "chromosome": "1", "start_pos": 12702069, "end_pos": 12652947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065374.2", "url": "https://www.ensembl.org/id/ENSSSCT00000065374.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037614.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037614.2" } ] } }, { "isoform_ac": "A0A4X1VSD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8/entry#A0A4X1VSD8-1", "sequence": { "sequence": "MDSSADPRNASNCTDPFSPSSMCSPVPSPSSWVNFSHLEGNLSDPCIRNRTELGGSDSLCPPTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRNGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP", "length": 401, "header": "tr|A0A4X1VSD8-1|A0A4X1VSD8_PIG Isoform 1 of Mu-type opioid receptor OS=Sus scrofa OX=9823 GN=OPRM1 PE=3 SV=1 CANONICAL=A0A4X1VSD8-1" }, "locus": { "chromosome": "1", "start_pos": 12702069, "end_pos": 12634567, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086175.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086175.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060700.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060700.1" } ] } }, { "isoform_ac": "F1S7X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8/entry#F1S7X7-1", "sequence": { "sequence": "MDSSADPRNASNCTDPFSPSSMCSPVPSPSSWVNFSHLEGNLSDPCIRNRTELGGSDSLCPPTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRNGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTRDHPSTANTVDRTNHQPPLAVGMPEVFTYSPPTHAEKTCNSYMQR", "length": 418, "header": "tr|F1S7X7-1|A0A4X1VSD8_PIG Computationally mapped isoform of Mu-type opioid receptor OS=Sus scrofa OX=9823 GN=OPRM1 PE=3 SV=4 CANONICAL=A0A4X1VSD8-1" }, "locus": { "chromosome": "1", "start_pos": 12702069, "end_pos": 12528675, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004503.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004503.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004401.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004401.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S7X7", "url": "https://www.uniprot.org/uniprotkb/F1S7X7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-111885", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111885", "resource": "Reactome", "description": "Opioid Signalling" }, { "id": "R-SSC-202040", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202040", "resource": "Reactome", "description": "G-protein activation" }, { "id": "R-SSC-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "beta-endorphin receptor activity", "id": "GO:0004979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004979", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "G-protein beta-subunit binding", "id": "GO:0031681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031681", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "morphine receptor activity", "id": "GO:0038047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038047", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "neuropeptide binding", "id": "GO:0042923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042923", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "sensory perception of pain", "id": "GO:0019233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019233", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "behavioral response to ethanol", "id": "GO:0048149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048149", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "G protein-coupled opioid receptor signaling pathway", "id": "GO:0038003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038003", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "negative regulation of Wnt protein secretion", "id": "GO:0061358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061358", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" }, { "name": "regulation of cellular response to stress", "id": "GO:0080135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080135", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VSD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1VSD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VSD8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 339, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 49, "end_pos": 51 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VJN4-1", "uniprot_ac": "A0A4X1VJN4", "uniprot_id": "A0A4X1VJN4_PIG", "mass": { "chemical_mass": 18453.0, "monoisotopic_mass": 18453.0 }, "refseq": { "ac": "XP_005666908", "name": "interleukin-15 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666908" }, "gene_names": [ { "name": "IL15", "type": "recommended", "evidence": [ { "id": "A0A4X1VJN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ] }, { "name": "IL-15", "type": "synonym", "evidence": [ { "id": "XP_005666908", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666908" } ] }, { "name": "IL15", "type": "synonym", "evidence": [ { "id": "XP_005666908", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666908" } ] } ], "protein_names": [ { "name": "Interleukin", "type": "recommended", "evidence": [ { "id": "A0A4X1VJN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4/entry#names_and_taxonomy" } ] }, { "name": "interleukin-15 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005666908", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666908" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IL15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4", "locus": { "chromosome": "8", "start_pos": 85667321, "end_pos": 85678461, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009051", "url": "https://www.ensembl.org/id/ENSSSCG00000009051" } ] } } ], "crossref": [ { "id": "ENSSSCG00000009051", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009051", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "397683", "url": "https://www.ncbi.nlm.nih.gov/gene/397683", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FVWGCIS", "url": "https://omabrowser.org/oma/group/FVWGCIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1VJN4", "url": "https://www.orthodb.org/?gene=A0A4X1VJN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14356", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14356", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14356:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14356:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8983432", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8983432", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005666908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666908", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1VGY3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VGY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VJN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GNZ5", "url": "https://www.uniprot.org/uniprotkb/K7GNZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GNZ5-1", "url": "https://www.uniprot.org/uniprotkb/K7GNZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRILKPYLRSTCIQCYLCLLLNSHFLTEAGIHVFILGCISAGLPKTEATWQHVISDLKKIEDLIRSIHMDATLYTESDAHPNCKVTAMKCFLLELRVILQESRNSDISDTVENLIILANSSLSSIEYKTESGCKECEELEEKNINEFLKSFIHIVQMFINPS", "length": 162, "header": "tr|A0A4X1VJN4-1|A0A4X1VJN4_PIG Isoform 1 of Interleukin OS=Sus scrofa OX=9823 GN=IL15 PE=3 SV=1 CANONICAL=A0A4X1VJN4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1VGY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4/entry#A0A4X1VGY3-1", "sequence": { "sequence": "ISTCIQCYLCLLLNSHFLTEAGIHVFILGCISAGLPKTEATWQHVISDLKKIEDLIRSIHMDATLYTESDAHPNCKVTAMKCFLLELRVILQESRNSDISDTVENLIILANSSLSSIEYKTESGCKECEELEEKNINEFLKSFIHIVQMFINPS", "length": 154, "header": "tr|A0A4X1VGY3-1|A0A4X1VJN4_PIG Computationally mapped isoform of Interleukin OS=Sus scrofa OX=9823 GN=IL15 PE=3 SV=1 CANONICAL=A0A4X1VJN4-1" }, "locus": { "chromosome": "8", "start_pos": 85677837, "end_pos": 85668369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032937.4", "url": "https://www.ensembl.org/id/ENSSSCT00000032937.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028557.3", "url": "https://www.ensembl.org/id/ENSSSCP00000028557.3" } ] } }, { "isoform_ac": "A0A4X1VJN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4/entry#A0A4X1VJN4-1", "sequence": { "sequence": "MRILKPYLRSTCIQCYLCLLLNSHFLTEAGIHVFILGCISAGLPKTEATWQHVISDLKKIEDLIRSIHMDATLYTESDAHPNCKVTAMKCFLLELRVILQESRNSDISDTVENLIILANSSLSSIEYKTESGCKECEELEEKNINEFLKSFIHIVQMFINPS", "length": 162, "header": "tr|A0A4X1VJN4-1|A0A4X1VJN4_PIG Isoform 1 of Interleukin OS=Sus scrofa OX=9823 GN=IL15 PE=3 SV=1 CANONICAL=A0A4X1VJN4-1" }, "locus": { "chromosome": "8", "start_pos": 85678374, "end_pos": 85668369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076031.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076031.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065389.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065389.1" } ] } }, { "isoform_ac": "K7GNZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4/entry#K7GNZ5-1", "sequence": { "sequence": "MANVYLYIYIVSEVPLVKYILKNFKPYLRSTCIQCYLCLLLNSHFLTEAGIHVFILGCISAGLPKTEATWQHVISDLKKIEDLIRSIHMDATLYTESDAHPNCKVTAMKCFLLELRVILQESRNSDISDTVENLIILANSSLSSIEYKTESGCKECEELEEKNINEFLKSFIHIVQMFINPS", "length": 182, "header": "tr|K7GNZ5-1|A0A4X1VJN4_PIG Computationally mapped isoform of Interleukin OS=Sus scrofa OX=9823 GN=IL15 PE=3 SV=3 CANONICAL=A0A4X1VJN4-1" }, "locus": { "chromosome": "8", "start_pos": 85677502, "end_pos": 85668369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036525.4", "url": "https://www.ensembl.org/id/ENSSSCT00000036525.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029602.3", "url": "https://www.ensembl.org/id/ENSSSCP00000029602.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "K7GNZ5", "url": "https://www.uniprot.org/uniprotkb/K7GNZ5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8983432", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8983432", "resource": "Reactome", "description": "Interleukin-15 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "P40933-1", "protein_name": "Interleukin-15", "gene_name": "IL15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRISKPHLRSISIQCYLCLLLNSHFLTEAGIHVFILGCFSAGLPKTEANWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS", "length": 162 }, "evidence": [ { "id": "A0A4X1VJN4", "url": "https://omabrowser.org/oma/group/A0A4X1VJN4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P48346-1", "protein_name": "Interleukin-15", "gene_name": "Il15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKILKPYMRNTSISCYLCFLLNSHFLTEAGIHVFILGCVSVGLPKTEANWIDVRYDLEKIESLIQSIHIDTTLYTDSDFHPSCKVTAMNCFLLELQVILHEYSNMTLNETVRNVLYLANSTLSSNKNVAESGCKECEELEEKTFTEFLQSFIRIVQMFINTS", "length": 162 }, "evidence": [ { "id": "A0A4X1VJN4", "url": "https://omabrowser.org/oma/group/A0A4X1VJN4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P97604-1", "protein_name": "Interleukin-15", "gene_name": "Il15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKILKPYMRNTSILYYLCFLLNSHFLTEAGIHVFILGCVSVGLPKTEANWIDVRYDLEKIESLIQFIHIDTTLYTDSDFHPSCKVTAMNCFLLELQVILHEYSNMTLNETVRNVLYLANSTLSSNKNVIESGCKECEELEERNFTEFLQSFIHIVQMFINTS", "length": 162 }, "evidence": [ { "id": "A0A4X1VJN4", "url": "https://omabrowser.org/oma/group/A0A4X1VJN4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q28028-1", "protein_name": "Interleukin-15", "gene_name": "IL15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRILKPYLRSTSIQCYLCLLLNSHFLTEAGIHVFILGCISASLPKTEANWQYVINDLKTIEHLIQSIHMDATLYTESDAHPNCKVTAMQCFLLELRVILHESKNATIYEIIENLTMLANSNLSSIENKTELGCKECEELEEKSIKEFLKSFVHIVQMFINTS", "length": 162 }, "evidence": [ { "id": "A0A4X1VJN4", "url": "https://omabrowser.org/oma/group/A0A4X1VJN4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "positive regulation of interleukin-17 production", "id": "GO:0032740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032740", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "positive regulation of cytokine production", "id": "GO:0001819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001819", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "positive regulation of phagocytosis", "id": "GO:0050766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "positive regulation of T cell proliferation", "id": "GO:0042102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042102", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "positive regulation of immune response", "id": "GO:0050778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050778", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "neutrophil activation", "id": "GO:0042119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042119", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "macrophage differentiation", "id": "GO:0030225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030225", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "interleukin-15-mediated signaling pathway", "id": "GO:0035723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "negative regulation of cold-induced thermogenesis", "id": "GO:0120163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120163", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" }, { "name": "cytokine receptor binding", "id": "GO:0005126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005126", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U0L4-1", "uniprot_ac": "A0A4X1U0L4", "uniprot_id": "A0A4X1U0L4_PIG", "mass": { "chemical_mass": 29231.0, "monoisotopic_mass": 29231.0 }, "refseq": { "ac": "NP_001231871", "name": "replication protein A 32 kDa subunit", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231871" }, "gene_names": [ { "name": "RPA2", "type": "recommended", "evidence": [ { "id": "A0A4X1U0L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ] }, { "name": "RPA2", "type": "synonym", "evidence": [ { "id": "NP_001231871", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231871" } ] } ], "protein_names": [ { "name": "Replication protein A 32 kDa subunit", "type": "recommended", "evidence": [ { "id": "A0A4X1U0L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4/entry#names_and_taxonomy" } ] }, { "name": "Replication factor A protein 2", "type": "synonym", "evidence": [ { "id": "A0A4X1U0L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4/entry#names_and_taxonomy" } ] }, { "name": "replication protein A 32 kDa subunit", "type": "synonym", "evidence": [ { "id": "NP_001231871", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231871" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPA2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4", "locus": { "chromosome": "6", "start_pos": 85031582, "end_pos": 85045915, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003583", "url": "https://www.ensembl.org/id/ENSSSCG00000003583" } ] } } ], "crossref": [ { "id": "ENSSSCG00000003583", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003583", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04478", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04478", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100514295", "url": "https://www.ncbi.nlm.nih.gov/gene/100514295", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514295", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514295", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SFGNKRY", "url": "https://omabrowser.org/oma/group/SFGNKRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U0L4", "url": "https://www.orthodb.org/?gene=A0A4X1U0L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13989", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13989", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13989:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13989:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08784", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08784", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-110312", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110312", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-110314", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110314", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-110320", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-174437", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174437", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-176187", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176187", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3371453", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5358565", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358565", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5358606", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358606", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5651801", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5651801", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5655862", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5655862", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5656121", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656121", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5656169", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656169", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5685938", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5685938", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5685942", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5685942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5693537", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693537", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5693607", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693607", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5696395", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696395", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5696397", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696397", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5696400", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696400", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6782135", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782135", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6782210", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6804756", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804756", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68962", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68962", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-69166", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-69473", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69473", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001231871", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231871", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U0L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RE33", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RE33-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STM9", "url": "https://www.uniprot.org/uniprotkb/F1STM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STM9-1", "url": "https://www.uniprot.org/uniprotkb/F1STM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWNSGFESYSSSSFGGAGGYTQSPGGFGSPTPSQAEKKSRARAQHIVPCTISQLLSATLVDEVFKIGNVEISQVTIVGIIRHAEKAATNIVYKIDDMTAAPMDVRQWVDTDDASGENTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVVNAHMLLNKSNSQLLAGRVPVSNPGMGEVGSFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLQHMSVASIKQAVDFLSNEGHIYSTVDDDHFKSTDAE", "length": 270, "header": "tr|A0A4X1U0L4-1|A0A4X1U0L4_PIG Isoform 1 of Replication protein A 32 kDa subunit OS=Sus scrofa OX=9823 GN=RPA2 PE=1 SV=1 CANONICAL=A0A4X1U0L4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U0L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4/entry#A0A4X1U0L4-1", "sequence": { "sequence": "MWNSGFESYSSSSFGGAGGYTQSPGGFGSPTPSQAEKKSRARAQHIVPCTISQLLSATLVDEVFKIGNVEISQVTIVGIIRHAEKAATNIVYKIDDMTAAPMDVRQWVDTDDASGENTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVVNAHMLLNKSNSQLLAGRVPVSNPGMGEVGSFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLQHMSVASIKQAVDFLSNEGHIYSTVDDDHFKSTDAE", "length": 270, "header": "tr|A0A4X1U0L4-1|A0A4X1U0L4_PIG Isoform 1 of Replication protein A 32 kDa subunit OS=Sus scrofa OX=9823 GN=RPA2 PE=1 SV=1 CANONICAL=A0A4X1U0L4-1" }, "locus": { "chromosome": "6", "start_pos": 85045792, "end_pos": 85033209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091050.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091050.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073812.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073812.1" } ] } }, { "isoform_ac": "A0A5G2RE33-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4/entry#A0A5G2RE33-1", "sequence": { "sequence": "LKPGGFESYSSSSFGGAGGYTQSPGGFGSPTPSQAEKKSRARAQHIVPCTISQLLSATLVDEVFKIGNVEISQVTIVGIIRHAEKAATNIVYKIDDMTAAPMDVRQWVDTDDASGENTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVVNAHMLLNKSNSQLLAGRVPVSNPGMGEVGSFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLQHMSVASIKQAVDFLSNEGHIYSTVDDDHFKSTDAE", "length": 270, "header": "tr|A0A5G2RE33-1|A0A4X1U0L4_PIG Computationally mapped isoform of Replication protein A 32 kDa subunit OS=Sus scrofa OX=9823 GN=RPA2 PE=1 SV=1 CANONICAL=A0A4X1U0L4-1" }, "locus": { "chromosome": "6", "start_pos": 85045548, "end_pos": 85033209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077144.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077144.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072826.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072826.1" } ] } }, { "isoform_ac": "F1STM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4/entry#F1STM9-1", "sequence": { "sequence": "LKPGGFESYSSSSFGGAGGYTQSPGGFGSPTPSQAEKKSRARAQHIVPCTISQLLSATLVDEVFKIGNVEISQVTIVGIIRHAEKAATNIVYKIDDMTAAPMDVRQWVDTDDASGENTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVVNAHMLLNKSNSQLLAGRVPVSNPGMANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLQHMSVASIKQAVDFLSNEGHIYSTVDDDHFKSTDAE", "length": 257, "header": "tr|F1STM9-1|F1STM9_PIG Computationally mapped isoform of Replication protein A 32 kDa subunit OS=Sus scrofa OX=9823 GN=RPA2 PE=1 SV=3 CANONICAL=A0A4X1U0L4-1" }, "locus": { "chromosome": "6", "start_pos": 85045548, "end_pos": 85033209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003978.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003978.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003887.4", "url": "https://www.ensembl.org/id/ENSSSCP00000003887.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 31, "start_aa": "Thr", "end_pos": 31, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr31", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RE33", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RE33" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514295", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514295", "resource": "KEGG Pathway" }, { "id": "R-SSC-110312", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110312", "resource": "Reactome", "description": "Translesion synthesis by REV1" }, { "id": "R-SSC-110314", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110314", "resource": "Reactome", "description": "Recognition of DNA damage by PCNA-containing replication complex" }, { "id": "R-SSC-110320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110320", "resource": "Reactome", "description": "Translesion Synthesis by POLH" }, { "id": "R-SSC-174437", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174437", "resource": "Reactome", "description": "Removal of the Flap Intermediate from the C-strand" }, { "id": "R-SSC-176187", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176187", "resource": "Reactome", "description": "Activation of ATR in response to replication stress" }, { "id": "R-SSC-3371453", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "resource": "Reactome", "description": "Regulation of HSF1-mediated heat shock response" }, { "id": "R-SSC-5358565", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358565", "resource": "Reactome", "description": "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" }, { "id": "R-SSC-5358606", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358606", "resource": "Reactome", "description": "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" }, { "id": "R-SSC-5651801", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5651801", "resource": "Reactome", "description": "PCNA-Dependent Long Patch Base Excision Repair" }, { "id": "R-SSC-5655862", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5655862", "resource": "Reactome", "description": "Translesion synthesis by POLK" }, { "id": "R-SSC-5656121", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656121", "resource": "Reactome", "description": "Translesion synthesis by POLI" }, { "id": "R-SSC-5656169", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656169", "resource": "Reactome", "description": "Termination of translesion DNA synthesis" }, { "id": "R-SSC-5685938", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5685938", "resource": "Reactome", "description": "HDR through Single Strand Annealing (SSA)" }, { "id": "R-SSC-5685942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5685942", "resource": "Reactome", "description": "HDR through Homologous Recombination (HRR)" }, { "id": "R-SSC-5693537", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693537", "resource": "Reactome", "description": "Resolution of D-Loop Structures" }, { "id": "R-SSC-5693607", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693607", "resource": "Reactome", "description": "Processing of DNA double-strand break ends" }, { "id": "R-SSC-5696395", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696395", "resource": "Reactome", "description": "Formation of Incision Complex in GG-NER" }, { "id": "R-SSC-5696397", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696397", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in GG-NER" }, { "id": "R-SSC-5696400", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696400", "resource": "Reactome", "description": "Dual Incision in GG-NER" }, { "id": "R-SSC-6782135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782135", "resource": "Reactome", "description": "Dual incision in TC-NER" }, { "id": "R-SSC-6782210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782210", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in TC-NER" }, { "id": "R-SSC-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" }, { "id": "R-SSC-6804756", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804756", "resource": "Reactome", "description": "Regulation of TP53 Activity through Phosphorylation" }, { "id": "R-SSC-68962", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68962", "resource": "Reactome", "description": "Activation of the pre-replicative complex" }, { "id": "R-SSC-69166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69166", "resource": "Reactome", "description": "Removal of the Flap Intermediate" }, { "id": "R-SSC-69473", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69473", "resource": "Reactome", "description": "G2/M DNA damage checkpoint" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YNM4-1", "protein_name": "Replication factor A protein 2", "gene_name": "RPA2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MWGGQGNFDGGYGPAGGYTQSPGGFSSPTGAQAEKKQRSRSQSIVPCTVSQLLAAEQVDEAFRIHDVEISQVTVVGIVRHAEKAPTNILYKVDDMTAAPMDVRQWVDTDEAGSENIVVPPGTYVKVAGHLRSFQNKKSLVAFKIMPLENMNEFTTHILETVNAHMILRKNLTLASRAPQSFTSAGMSDVGGYGGGSLPVNGLTAHQSQVLNLIKNCHSPEGMSLQELKLQLHNVSIPTIKQAVEFLSSEGHIYSTVDDDHYKSTDAD", "length": 267 }, "evidence": [ { "id": "A0A4X1U0L4", "url": "https://omabrowser.org/oma/group/A0A4X1U0L4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWNSGFESYGSSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSATLVDEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSSENTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGRAPISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSIKQAVDFLSNEGHIYSTVDDDHFKSTDAE", "length": 270 }, "evidence": [ { "id": "A0A4X1U0L4", "url": "https://omabrowser.org/oma/group/A0A4X1U0L4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P26754-1", "protein_name": "Replication factor A protein 2", "gene_name": "RFA2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MATYQPYNEYSSVTGGGFENSESRPGSGESETNTRVNTLTPVTIKQILESKQDIQDGPFVSHNQELHHVCFVGVVRNITDHTANIFLTIEDGTGQIEVRKWSEDANDLAAGNDDSSGKGYGSQVAQQFEIGGYVKVFGALKEFGGKKNIQYAVIKPIDSFNEVLTHHLEVIKCHSIASGMMKQPLESASNNNGQSLFVKDDNDTSSGSSPLQRILEFCKKQCEGKDANSFAVPIPLISQSLNLDETTVRNCCTTLTDQGFIYPTFDDNNFFAL", "length": 273 }, "evidence": [ { "id": "A0A4X1U0L4", "url": "https://omabrowser.org/oma/group/A0A4X1U0L4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q62193-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "Rpa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWNSGFESFSSSTYGGAGGYTQSPGGFGSPTPSQAEKKSRVRAQHIVPCTISQLLSATLTDEVFRIGDVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAPPMDVRQWVDTDDASGENAVVPPETYVKVAGHLRSFQNKKSLVAFKIIPLEDMNEFTAHILEVVNSHMMLSKPNSQASAGRPSMSNPGMSEPGNFSGNNFMPANGLTVVQNQVLNLIKACPRPEGLNFQDLRSQLQHMPVPSIKQAVDFLCNEGHIYSTVDDDHFKSTDAE", "length": 270 }, "evidence": [ { "id": "A0A4X1U0L4", "url": "https://omabrowser.org/oma/group/A0A4X1U0L4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63528-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "Rpa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWNSGFESFSSSSYGAAGGYTQSPGGFGSPTPSQAEKKSRARAQHIVPCTISQLLSATLTDEVFKIGDVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDTSGENTVVPPETYVKVAGHLRSFQNKKSLVAFKIIPLEDMNEFTAHILEVVNSHLMLSKANSQASVGRPSMSNPGMGEPGNFSGNNFMPANGLTVVQNQVLNLIKACPRPEGLNFQDLRSQLQHMPVASIKQAVDFLCNEGHIYSTVDDDHFKSTDAE", "length": 270 }, "evidence": [ { "id": "A0A4X1U0L4", "url": "https://omabrowser.org/oma/group/A0A4X1U0L4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VIH1-1", "protein_name": "Replication protein A2, isoform A", "gene_name": "RPA2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNDSFGDFNATQTAPTGAASNQKGEGIVPLVVKQIVDAPEGNIELFGMQYAMACVVAIVRNVETSSTKITYTLEDHSGRIDAHYWLEEGDALKAPEVMVNNYVKVYGTTRSQGGSKTLMIFKLLPVLDPNEVCTHLLEVLNARYRAEDYQSKGGAGAGAGASSGSGSIADFTASQSSAIVSGLEPKQQAVFQAIKSNVSEEGISRKELKAKFSHISDSELTNILDFMISEGHIYSSIDADHFICTM", "length": 246 }, "evidence": [ { "id": "A0A4X1U0L4", "url": "https://omabrowser.org/oma/group/A0A4X1U0L4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "G-rich strand telomeric DNA binding", "id": "GO:0098505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098505", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "regulation of DNA damage checkpoint", "id": "GO:2000001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000001", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "mismatch repair", "id": "GO:0006298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006298", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "protein localization to chromosome", "id": "GO:0034502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034502", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "regulation of double-strand break repair via homologous recombination", "id": "GO:0010569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010569", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "mitotic G1 DNA damage checkpoint signaling", "id": "GO:0031571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031571", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "DNA replication factor A complex", "id": "GO:0005662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005662", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0L4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U0L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0L4" }, { "id": "PF08784", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08784" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Replication protein A C-terminal", "eco_id": "ECO_0000259", "start_pos": 166, "end_pos": 262, "start_aa": "His", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 31 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UC72-1", "uniprot_ac": "A0A4X1UC72", "uniprot_id": "A0A4X1UC72_PIG", "mass": { "chemical_mass": 25079.0, "monoisotopic_mass": 25079.0 }, "refseq": { "ac": "XP_003129362", "name": "eukaryotic translation initiation factor 4E isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129362" }, "gene_names": [ { "name": "EIF4E", "type": "recommended", "evidence": [ { "id": "A0A4X1UC72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ] }, { "name": "EIF4E", "type": "synonym", "evidence": [ { "id": "XP_003129362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129362" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 4E", "type": "recommended", "evidence": [ { "id": "A0A4X1UC72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72/entry#names_and_taxonomy" } ] }, { "name": "eukaryotic translation initiation factor 4E isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003129362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129362" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EIF4E", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72", "locus": { "chromosome": "8", "start_pos": 121464471, "end_pos": 121409731, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000028420", "url": "https://www.ensembl.org/id/ENSSSCG00000028420" } ] } } ], "crossref": [ { "id": "A0A4X1UC72", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UC72", "database": "AlphaFoldDB", "categories": [] }, { "id": "100038030", "url": "https://www.ncbi.nlm.nih.gov/gene/100038030", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100038030", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100038030", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EEFWAIV", "url": "https://omabrowser.org/oma/group/EEFWAIV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UC72", "url": "https://www.orthodb.org/?gene=A0A4X1UC72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11960", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11960", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11960:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11960:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1169408", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1169408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-159227", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159227", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-159230", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-159231", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-166208", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-166208", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-429947", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72662", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72662", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003129362", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129362", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UC72-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FB27", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FB27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FB27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FB27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATVEPETTPTPNPPPTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV", "length": 217, "header": "tr|A0A4X1UC72-1|A0A4X1UC72_PIG Isoform 1 of Eukaryotic translation initiation factor 4E OS=Sus scrofa OX=9823 GN=EIF4E PE=1 SV=1 CANONICAL=A0A4X1UC72-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UC72-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72/entry#A0A4X1UC72-1", "sequence": { "sequence": "MATVEPETTPTPNPPPTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV", "length": 217, "header": "tr|A0A4X1UC72-1|A0A4X1UC72_PIG Isoform 1 of Eukaryotic translation initiation factor 4E OS=Sus scrofa OX=9823 GN=EIF4E PE=1 SV=1 CANONICAL=A0A4X1UC72-1" }, "locus": { "chromosome": "8", "start_pos": 121461319, "end_pos": 121409740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069845.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069845.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073925.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073925.1" } ] } }, { "isoform_ac": "A0A8W4FB27-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72/entry#A0A8W4FB27-1", "sequence": { "sequence": "FFAHVLETTPTPNPPPTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV", "length": 217, "header": "tr|A0A8W4FB27-1|A0A4X1UC72_PIG Computationally mapped isoform of Eukaryotic translation initiation factor 4E OS=Sus scrofa OX=9823 GN=EIF4E PE=1 SV=1 CANONICAL=A0A4X1UC72-1" }, "locus": { "chromosome": "8", "start_pos": 121461319, "end_pos": 121409880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104035.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104035.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075493.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075493.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FB27", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FB27" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100038030", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100038030", "resource": "KEGG Pathway" }, { "id": "R-SSC-1169408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1169408", "resource": "Reactome", "description": "ISG15 antiviral mechanism" }, { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-159227", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159227", "resource": "Reactome", "description": "Transport of the SLBP independent Mature mRNA" }, { "id": "R-SSC-159230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159230", "resource": "Reactome", "description": "Transport of the SLBP Dependant Mature mRNA" }, { "id": "R-SSC-159231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159231", "resource": "Reactome", "description": "Transport of Mature mRNA Derived from an Intronless Transcript" }, { "id": "R-SSC-166208", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-166208", "resource": "Reactome", "description": "mTORC1-mediated signalling" }, { "id": "R-SSC-429947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429947", "resource": "Reactome", "description": "Deadenylation of mRNA" }, { "id": "R-SSC-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-SSC-72662", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72662", "resource": "Reactome", "description": "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S" }, { "id": "R-SSC-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" } ], "orthologs": [ { "uniprot_canonical_ac": "O04663-1", "protein_name": "Eukaryotic translation initiation factor isoform 4E", "gene_name": "EIF(ISO)4E", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATDDVNEPLPAAAELPATEAEKQPHKLERKWSFWFDNQSKKGAAWGASLRKAYTFDTVEDFWGLHETIFQTSKLTANAEIHLFKAGVEPKWEDPECANGGKWTWVVTANRKEALDKGWLETLMALIGEQFDEADEICGVVASVRPQSKQDKLSLWTRTKSNEAVLMGIGKKWKEILDVTDKITFNNHDDSRRSRFTV", "length": 198 }, "evidence": [ { "id": "A0A4X1UC72", "url": "https://omabrowser.org/oma/group/A0A4X1UC72/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P07260-1", "protein_name": "Eukaryotic translation initiation factor 4E", "gene_name": "CDC33", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSVEEVSKKFEENVSVDDTTATPKTVLSDSAHFDVKHPLNTKWTLWYTKPAVDKSESWSDLLRPVTSFQTVEEFWAIIQNIPEPHELPLKSDYHVFRNDVRPEWEDEANAKGGKWSFQLRGKGADIDELWLRTLLAVIGETIDEDDSQINGVVLSIRKGGNKFALWTKSEDKEPLLRIGGKFKQVLKLTDDGHLEFFPHSSANGRHPQPSITL", "length": 213 }, "evidence": [ { "id": "A0A4X1UC72", "url": "https://omabrowser.org/oma/group/A0A4X1UC72/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P48598-1", "protein_name": "Eukaryotic translation initiation factor 4E1", "gene_name": "eIF4E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQSDFHRMKNFANPKSMFKTSAPSTEQGRPEPPTSAAAPAEAKDVKPKEDPQETGEPAGNTATTTAPAGDDAVRTEHLYKHPLMNVWTLWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKSSKTDLDNLWLDVLLCLIGEAFDHSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL", "length": 259 }, "evidence": [ { "id": "A0A4X1UC72", "url": "https://omabrowser.org/oma/group/A0A4X1UC72/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P63073-1", "protein_name": "Eukaryotic translation initiation factor 4E", "gene_name": "Eif4e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV", "length": 217 }, "evidence": [ { "id": "A0A4X1UC72", "url": "https://omabrowser.org/oma/group/A0A4X1UC72/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q55FE0-1", "protein_name": "Eukaryotic translation initiation factor 4E", "gene_name": "eif4e", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTNKDVECLVEPTSNISITEENKNVTSETTTTTNNTQNKETETTDNINKEETADKENKEEQQQEENPENLIKHPLQNRWSLWYDYQSGKINPEHWVDSLKKVISFDSVEDFWCVFNNLPNVSNLKQGSSYHLFKDDIEPKWEHESNKRGGKWFVMVKDKSRCDNQWLQSVMACVGETFDSSDEICGIVYNSRKNGDKISVWTKTAQDEKATRDVGNCLKKILEIDQTIQYTPHEDFIRSSKGSKNLYEC", "length": 250 }, "evidence": [ { "id": "A0A4X1UC72", "url": "https://omabrowser.org/oma/group/A0A4X1UC72/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9N0T5-1", "protein_name": "Eukaryotic translation initiation factor 4E", "gene_name": "EIF4E", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATVEPETTPTPNPPPTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETVLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV", "length": 217 }, "evidence": [ { "id": "A0A4X1UC72", "url": "https://omabrowser.org/oma/group/A0A4X1UC72/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 4F complex", "id": "GO:0016281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016281", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "RISC complex", "id": "GO:0016442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016442", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "excitatory synapse", "id": "GO:0060076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060076", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "chromatoid body", "id": "GO:0033391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033391", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "positive regulation of mitotic cell cycle", "id": "GO:0045931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045931", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "regulation of translation at postsynapse, modulating synaptic transmission", "id": "GO:0099578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099578", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "RNA 7-methylguanosine cap binding", "id": "GO:0000340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000340", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "mRNA cap binding", "id": "GO:0098808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098808", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "eukaryotic initiation factor 4G binding", "id": "GO:0031370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031370", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC72", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1US56-1", "uniprot_ac": "A0A4X1US56", "uniprot_id": "A0A4X1US56_PIG", "mass": { "chemical_mass": 23315.0, "monoisotopic_mass": 23315.0 }, "refseq": { "ac": "XP_020934018", "name": "synaptosomal-associated protein 25 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934018" }, "gene_names": [ { "name": "SNAP25", "type": "recommended", "evidence": [ { "id": "A0A4X1US56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ] }, { "name": "SNAP25", "type": "synonym", "evidence": [ { "id": "XP_020934018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934018" } ] } ], "protein_names": [ { "name": "Multifunctional fusion protein", "type": "recommended", "evidence": [ { "id": "A0A4X1US56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56/entry#names_and_taxonomy" } ] }, { "name": "synaptosomal-associated protein 25 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020934018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934018" } ] } ], "function": [ { "annotation": "t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.", "evidence": [ { "database": "UniProtKB", "id": "I3LAV3", "url": "https://www.uniprot.org/uniprotkb/I3LAV3#function" }, { "database": "UniProtKB", "id": "ARBA00045211", "url": "https://www.uniprot.org/uniprotkb/ARBA00045211#function" }, { "database": "UniProtKB", "id": "A0A287A467", "url": "https://www.uniprot.org/uniprotkb/A0A287A467#function" }, { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56#function" } ] }, { "annotation": "t-SNARE involved in the molecular regulation of neurotransmitter release. Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.", "evidence": [ { "database": "UniProtKB", "id": "I3LAV3", "url": "https://www.uniprot.org/uniprotkb/I3LAV3#function" }, { "database": "UniProtKB", "id": "RU369075", "url": "https://www.uniprot.org/uniprotkb/RU369075#function" }, { "database": "UniProtKB", "id": "A0A287A467", "url": "https://www.uniprot.org/uniprotkb/A0A287A467#function" }, { "database": "UniProtKB", "id": "A0A8W4FEB3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEB3#function" }, { "database": "UniProtKB", "id": "A0A287BN13", "url": "https://www.uniprot.org/uniprotkb/A0A287BN13#function" }, { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SNAP25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56", "locus": { "chromosome": "17", "start_pos": 19227576, "end_pos": 19141464, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026985", "url": "https://www.ensembl.org/id/ENSSSCG00000026985" } ] } } ], "crossref": [ { "id": "A0A4X1US56", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1US56", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026985", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026985", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15885", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15885", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15894", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15894", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100620588", "url": "https://www.ncbi.nlm.nih.gov/gene/100620588", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100620588", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620588", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GMIQINE", "url": "https://omabrowser.org/oma/group/GMIQINE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "I3LAV3", "url": "https://www.orthodb.org/?gene=I3LAV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19305", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19305", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19305:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19305:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-181429", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-181429", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-181430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-181430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-210500", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-210500", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-212676", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-264642", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264642", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-449836", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-449836", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-888590", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-888590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020934018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934018", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A467", "url": "https://www.uniprot.org/uniprotkb/A0A287A467", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A467-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A467-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BN13", "url": "https://www.uniprot.org/uniprotkb/A0A287BN13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BN13-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BN13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1US56-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEB3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LAV3", "url": "https://www.uniprot.org/uniprotkb/I3LAV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LAV3-1", "url": "https://www.uniprot.org/uniprotkb/I3LAV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 206, "header": "tr|A0A4X1US56-1|A0A4X1US56_PIG Isoform 1 of Multifunctional fusion protein OS=Sus scrofa OX=9823 GN=SNAP25 PE=1 SV=1 CANONICAL=A0A4X1US56-1" }, "isoforms": [ { "isoform_ac": "A0A287A467-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56/entry#A0A287A467-1", "sequence": { "sequence": "MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVMLDEQGEQLDRVEEGMNHINQDMKEAEKNLKDLGKCCGLFICPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 194, "header": "tr|A0A287A467-1|A0A4X1US56_PIG Computationally mapped isoform of Multifunctional fusion protein OS=Sus scrofa OX=9823 GN=SNAP25 PE=1 SV=2 CANONICAL=A0A4X1US56-1" }, "locus": { "chromosome": "17", "start_pos": 19226366, "end_pos": 19193163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045585.2", "url": "https://www.ensembl.org/id/ENSSSCT00000045585.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038757.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038757.2" } ] } }, { "isoform_ac": "A0A287BN13-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56/entry#A0A287BN13-1", "sequence": { "sequence": "MAEDADMRNELEEMQRRADQLADESKDAGIRTLVMLDEQGEQLDRVEEGMNHINQDMKEAEKNLKDLGKCCGLFICPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 192, "header": "tr|A0A287BN13-1|A0A4X1US56_PIG Computationally mapped isoform of Multifunctional fusion protein OS=Sus scrofa OX=9823 GN=SNAP25 PE=1 SV=1 CANONICAL=A0A4X1US56-1" }, "locus": { "chromosome": "17", "start_pos": 19226366, "end_pos": 19193163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053460.2", "url": "https://www.ensembl.org/id/ENSSSCT00000053460.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057896.2", "url": "https://www.ensembl.org/id/ENSSSCP00000057896.2" } ] } }, { "isoform_ac": "A0A4X1US56-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56/entry#A0A4X1US56-1", "sequence": { "sequence": "MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 206, "header": "tr|A0A4X1US56-1|A0A4X1US56_PIG Isoform 1 of Multifunctional fusion protein OS=Sus scrofa OX=9823 GN=SNAP25 PE=1 SV=1 CANONICAL=A0A4X1US56-1" }, "locus": { "chromosome": "17", "start_pos": 19226366, "end_pos": 19193163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061808.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061808.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053403.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053403.1" } ] } }, { "isoform_ac": "A0A8W4FEB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56/entry#A0A8W4FEB3-1", "sequence": { "sequence": "MAEDADMRNELEEMQRRADQLADESLESTRQQLDRVEEGMNHINQDMKEAEKNLKDLGKCCGLFICPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 182, "header": "tr|A0A8W4FEB3-1|A0A4X1US56_PIG Computationally mapped isoform of Multifunctional fusion protein OS=Sus scrofa OX=9823 GN=SNAP25 PE=1 SV=1 CANONICAL=A0A4X1US56-1" }, "locus": { "chromosome": "17", "start_pos": 19226366, "end_pos": 19193163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100584.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100584.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077649.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077649.1" } ] } }, { "isoform_ac": "I3LAV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56/entry#I3LAV3-1", "sequence": { "sequence": "MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLDRVEEGMNHINQDMKEAEKNLKDLGKCCGLFICPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 206, "header": "tr|I3LAV3-1|A0A4X1US56_PIG Computationally mapped isoform of Multifunctional fusion protein OS=Sus scrofa OX=9823 GN=SNAP25 PE=1 SV=2 CANONICAL=A0A4X1US56-1" }, "locus": { "chromosome": "17", "start_pos": 19226366, "end_pos": 19193163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030392.3", "url": "https://www.ensembl.org/id/ENSSSCT00000030392.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021171.2", "url": "https://www.ensembl.org/id/ENSSSCP00000021171.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LAV3", "url": "https://www.uniprot.org/uniprotkb/I3LAV3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100620588", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620588", "resource": "KEGG Pathway" }, { "id": "R-SSC-181429", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-181429", "resource": "Reactome", "description": "Serotonin Neurotransmitter Release Cycle" }, { "id": "R-SSC-181430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-181430", "resource": "Reactome", "description": "Norepinephrine Neurotransmitter Release Cycle" }, { "id": "R-SSC-210500", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-210500", "resource": "Reactome", "description": "Glutamate Neurotransmitter Release Cycle" }, { "id": "R-SSC-212676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212676", "resource": "Reactome", "description": "Dopamine Neurotransmitter Release Cycle" }, { "id": "R-SSC-264642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264642", "resource": "Reactome", "description": "Acetylcholine Neurotransmitter Release Cycle" }, { "id": "R-SSC-449836", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-449836", "resource": "Reactome", "description": "Other interleukin signaling" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-888590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-888590", "resource": "Reactome", "description": "GABA synthesis, release, reuptake and degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LU73-1", "protein_name": "Multifunctional fusion protein", "gene_name": "Snap25", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLDRVEEGMNHINQDMKEAEKNLKDLGKCCGLFICPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 206 }, "evidence": [ { "id": "A0A4X1US56", "url": "https://omabrowser.org/oma/group/A0A4X1US56/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P36975-1", "protein_name": "Synaptosomal-associated protein 25", "gene_name": "Snap25", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPADPSEEVAPQVPKTELEELQINAQGVADESLESTRRMLALCEESKEAGIRTLVALDDQGEQLDRIEEGMDQINADMREAEKNLSGMEKCCGICVLPCNKSQSFKEDDGTWKGNDDGKVVNNQPQRVMDDRNGMMAQAGYIGRITNDAREDEMEENMGQVNTMIGNLRNMALDMGSELENQNRQIDRINRKGESNEARIAVANQRAHQLLK", "length": 212 }, "evidence": [ { "id": "A0A4X1US56", "url": "https://omabrowser.org/oma/group/A0A4X1US56/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P60878-1", "protein_name": "Synaptosomal-associated protein 25", "gene_name": "SNAP25", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 206 }, "evidence": [ { "id": "A0A4X1US56", "url": "https://omabrowser.org/oma/group/A0A4X1US56/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P60879-1", "protein_name": "Synaptosomal-associated protein 25", "gene_name": "Snap25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 206 }, "evidence": [ { "id": "A0A4X1US56", "url": "https://omabrowser.org/oma/group/A0A4X1US56/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P60880-1", "protein_name": "Synaptosomal-associated protein 25", "gene_name": "SNAP25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 206 }, "evidence": [ { "id": "A0A4X1US56", "url": "https://omabrowser.org/oma/group/A0A4X1US56/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P60881-1", "protein_name": "Synaptosomal-associated protein 25", "gene_name": "Snap25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 206 }, "evidence": [ { "id": "A0A4X1US56", "url": "https://omabrowser.org/oma/group/A0A4X1US56/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q17QQ3-1", "protein_name": "Synaptosomal-associated protein 25", "gene_name": "SNAP25", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 206 }, "evidence": [ { "id": "A0A4X1US56", "url": "https://omabrowser.org/oma/group/A0A4X1US56/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5TZ66-1", "protein_name": "Synaptosomal-associated protein 25-A", "gene_name": "snap25a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEDSDMRNELADMQQRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKDAEKNLNDLGKFCGLCSCPCNKMKSGASKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTDDARENEMDENLEQVGGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "length": 204 }, "evidence": [ { "id": "A0A4X1US56", "url": "https://omabrowser.org/oma/group/A0A4X1US56/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 17, "go_terms": [ { "name": "synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex", "id": "GO:0070032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070032", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "somatodendritic compartment", "id": "GO:0036477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036477", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "ribbon synapse", "id": "GO:0097470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097470", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "BLOC-1 complex", "id": "GO:0031083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031083", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of neuron projection development", "id": "GO:0010975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010975", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "presynaptic dense core vesicle exocytosis", "id": "GO:0099525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099525", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031629", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "synaptic vesicle priming", "id": "GO:0016082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016082", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "syntaxin-1 binding", "id": "GO:0017075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017075", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1US56", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1US56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1US56" }, { "id": "PS50192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-SNARE coiled-coil homology", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 81, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UUZ3-1", "uniprot_ac": "A0A4X1UUZ3", "uniprot_id": "A0A4X1UUZ3_PIG", "mass": { "chemical_mass": 23001.0, "monoisotopic_mass": 23001.0 }, "refseq": { "ac": "XP_003357447", "name": "ras-related protein Rab-7L1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357447" }, "gene_names": [ { "name": "RAB29", "type": "recommended", "evidence": [ { "id": "A0A4X1UUZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ] }, { "name": "RAB29", "type": "synonym", "evidence": [ { "id": "XP_003357447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357447" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab", "type": "recommended", "evidence": [ { "id": "A0A4X1UUZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-7L1", "type": "synonym", "evidence": [ { "id": "XP_003357447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357447" } ] } ], "function": [ { "annotation": "The small GTPases Rab are key regulators in vesicle trafficking.", "evidence": [ { "database": "UniProtKB", "id": "I3LHE8", "url": "https://www.uniprot.org/uniprotkb/I3LHE8#function" }, { "database": "UniProtKB", "id": "RU367128", "url": "https://www.uniprot.org/uniprotkb/RU367128#function" }, { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RAB29", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3", "locus": { "chromosome": "9", "start_pos": 66448953, "end_pos": 66458724, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026269", "url": "https://www.ensembl.org/id/ENSSSCG00000026269" } ] } } ], "crossref": [ { "id": "ENSSSCG00000026269", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026269", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04107", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04107", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626414", "url": "https://www.ncbi.nlm.nih.gov/gene/100626414", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626414", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626414", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NNFIGWT", "url": "https://omabrowser.org/oma/group/NNFIGWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UUZ3", "url": "https://www.orthodb.org/?gene=A0A4X1UUZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47981:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47981:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003357447", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357447", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UUZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LHE8", "url": "https://www.uniprot.org/uniprotkb/I3LHE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LHE8-1", "url": "https://www.uniprot.org/uniprotkb/I3LHE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDSEVVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGGPVPCLLLANKCDLSPWAVSRDQVDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMMSNSKEEMSLSTQGNYINLHTKPTSSWTCC", "length": 203, "header": "tr|A0A4X1UUZ3-1|A0A4X1UUZ3_PIG Isoform 1 of Ras-related protein Rab OS=Sus scrofa OX=9823 GN=RAB29 PE=3 SV=1 CANONICAL=A0A4X1UUZ3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UUZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3/entry#A0A4X1UUZ3-1", "sequence": { "sequence": "MSSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDSEVVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGGPVPCLLLANKCDLSPWAVSRDQVDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMMSNSKEEMSLSTQGNYINLHTKPTSSWTCC", "length": 203, "header": "tr|A0A4X1UUZ3-1|A0A4X1UUZ3_PIG Isoform 1 of Ras-related protein Rab OS=Sus scrofa OX=9823 GN=RAB29 PE=3 SV=1 CANONICAL=A0A4X1UUZ3-1" }, "locus": { "chromosome": "9", "start_pos": 66458249, "end_pos": 66451144, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039938.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039938.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053040.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053040.1" } ] } }, { "isoform_ac": "I3LHE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3/entry#I3LHE8-1", "sequence": { "sequence": "MRRKARDYATWGGTTSRAMSSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDSEVVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGGPVPCLLLANKCDLSPWAVSRDQVDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMMSNSKEEMSLSTQGNYINLHTKPTSSWTCC", "length": 221, "header": "tr|I3LHE8-1|A0A4X1UUZ3_PIG Computationally mapped isoform of Ras-related protein Rab OS=Sus scrofa OX=9823 GN=RAB29 PE=3 SV=2 CANONICAL=A0A4X1UUZ3-1" }, "locus": { "chromosome": "9", "start_pos": 66458719, "end_pos": 66451144, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028022.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028022.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023494.2", "url": "https://www.ensembl.org/id/ENSSSCP00000023494.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LHE8", "url": "https://www.uniprot.org/uniprotkb/I3LHE8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626414", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626414", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HKW6-1", "protein_name": "Ras-related protein Rab", "gene_name": "Rab29", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDSEMVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPSGDPVPCLLLANKSDLSPWAVSRDQIDRFSKENGFIGWTETSVKENRNINEAMRVLVEKMMNNSREDIISLSTQGNYINLQAKSSSGWTCC", "length": 204 }, "evidence": [ { "id": "A0A4X1UUZ3", "url": "https://omabrowser.org/oma/group/A0A4X1UUZ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1N9R7-1", "protein_name": "Ras-related protein Rab", "gene_name": "RAB7L1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGQRDRMFKVLVVGDATVGKTSLVQRYANDSFNRHYKSTVGVDFALKVVQWSESETVRLQLWDIAGQERFTSMTRLYYREASACVIMFDVTNVSTFSNSQKWKQDLDSKLTLPDGSPVPCLLLANKCDLSPWAVTREEVDRFSKENGFSGWVETSVKENKNINESMRVLIEKMMSSSTGDGSAAASWRGDYINIKETSPPGWACC", "length": 205 }, "evidence": [ { "id": "A0A4X1UUZ3", "url": "https://omabrowser.org/oma/group/A0A4X1UUZ3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O14966-1", "protein_name": "Ras-related protein Rab-29", "gene_name": "RAB29", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDYEIVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGEPVPCLLLANKCDLSPWAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMMRNSTEDIMSLSTQGDYINLQTKSSSWSCC", "length": 203 }, "evidence": [ { "id": "A0A4X1UUZ3", "url": "https://omabrowser.org/oma/group/A0A4X1UUZ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63481-1", "protein_name": "Ras-related protein Rab-29", "gene_name": "Rab29", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDSEMVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPSGEPVPCLLLANKSDLSPWAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLVEKMMNNSREDIMSSSTQGNYINLQTKPSPGWTCC", "length": 204 }, "evidence": [ { "id": "A0A4X1UUZ3", "url": "https://omabrowser.org/oma/group/A0A4X1UUZ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91YQ1-1", "protein_name": "Ras-related protein Rab-29", "gene_name": "Rab29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDSEMVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPSGEPVPCLLLANKSDLSPWAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLVEKMMNNSREDVMSLSTQGNYINLQAKPSSGWTCC", "length": 204 }, "evidence": [ { "id": "A0A4X1UUZ3", "url": "https://omabrowser.org/oma/group/A0A4X1UUZ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "kinase activator activity", "id": "GO:0019209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019209", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "dynein complex binding", "id": "GO:0070840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070840", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 17, "go_terms": [ { "name": "positive regulation of intracellular protein transport", "id": "GO:0090316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090316", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "positive regulation of T cell receptor signaling pathway", "id": "GO:0050862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050862", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "positive regulation of receptor recycling", "id": "GO:0001921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001921", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "host-mediated perturbation of viral process", "id": "GO:0044788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044788", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "cellular detoxification", "id": "GO:1990748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990748", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "regulation of motile cilium assembly", "id": "GO:1905503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905503", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" }, { "name": "melanosome organization", "id": "GO:0032438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032438", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UUZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TXU2-1", "uniprot_ac": "A0A4X1TXU2", "uniprot_id": "A0A4X1TXU2_PIG", "mass": { "chemical_mass": 30891.0, "monoisotopic_mass": 30891.0 }, "refseq": { "ac": "XP_005668846", "name": "proteasome activator complex subunit 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668846" }, "gene_names": [ { "name": "PSME3", "type": "recommended", "evidence": [ { "id": "A0A4X1TXU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2" } ] }, { "name": "PSME3", "type": "synonym", "evidence": [ { "id": "XP_005668846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668846" } ] } ], "protein_names": [ { "name": "Proteasome activator complex subunit 3", "type": "recommended", "evidence": [ { "id": "A0A4X1TXU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2/entry#names_and_taxonomy" } ] }, { "name": "Activator of multicatalytic protease subunit 3", "type": "synonym", "evidence": [ { "id": "A0A4X1TXU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2/entry#names_and_taxonomy" } ] }, { "name": "Proteasome activator 28 subunit gamma", "type": "synonym", "evidence": [ { "id": "A0A4X1TXU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2/entry#names_and_taxonomy" } ] }, { "name": "proteasome activator complex subunit 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005668846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668846" } ] } ], "function": [ { "annotation": "Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXS8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXS8#function" }, { "database": "UniProtKB", "id": "ARBA00037467", "url": "https://www.uniprot.org/uniprotkb/ARBA00037467#function" } ] }, { "annotation": "Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXS8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXS8#function" }, { "database": "UniProtKB", "id": "ARBA00045499", "url": "https://www.uniprot.org/uniprotkb/ARBA00045499#function" }, { "database": "UniProtKB", "id": "A0A900QFT4", "url": "https://www.uniprot.org/uniprotkb/A0A900QFT4#function" }, { "database": "UniProtKB", "id": "A0A8D1X9E3", "url": "https://www.uniprot.org/uniprotkb/A0A8D1X9E3#function" }, { "database": "UniProtKB", "id": "A0A4X1TXU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PSME3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2", "locus": { "chromosome": "12", "start_pos": 20028112, "end_pos": 20035557, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017385", "url": "https://www.ensembl.org/id/ENSSSCG00000017385" } ] } } ], "crossref": [ { "id": "A0A4X1TXU2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TXU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "397625", "url": "https://www.ncbi.nlm.nih.gov/gene/397625", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TXU2", "url": "https://www.orthodb.org/?gene=A0A4X1TXU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10660", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10660", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10660:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10660:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02251", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02251", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02252", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02252", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005668846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668846", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TST4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TST4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TST4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TST4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TXS8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TXS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TXU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TXU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1X9E3", "url": "https://www.uniprot.org/uniprotkb/A0A8D1X9E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1X9E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1X9E3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A900QFT4", "url": "https://www.uniprot.org/uniprotkb/A0A900QFT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A900QFT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A900QFT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKWILKKIKYLQSGGLSASHYNYKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY", "length": 265, "header": "tr|A0A4X1TXU2-1|A0A4X1TXU2_PIG Isoform 1 of Proteasome activator complex subunit 3 OS=Sus scrofa OX=9823 GN=PSME3 PE=3 SV=1 CANONICAL=A0A4X1TXU2-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TST4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2/entry#A0A4X1TST4-1", "sequence": { "sequence": "MASLLKVDQEVKLKVDSFRERITSEPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY", "length": 198, "header": "tr|A0A4X1TST4-1|A0A4X1TST4_PIG Computationally mapped isoform of Proteasome activator subunit 3 OS=Sus scrofa OX=9823 GN=PSME3 PE=3 SV=1 CANONICAL=A0A4X1TXU2-1" }, "locus": { "chromosome": "12", "start_pos": 20035345, "end_pos": 20030252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068269.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068269.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073175.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073175.1" } ] } }, { "isoform_ac": "A0A4X1TXS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2/entry#A0A4X1TXS8-1", "sequence": { "sequence": "MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY", "length": 231, "header": "tr|A0A4X1TXS8-1|A0A4X1TXS8_PIG Computationally mapped isoform of Proteasome activator complex subunit 1 OS=Sus scrofa OX=9823 GN=PSME3 PE=3 SV=1 CANONICAL=A0A4X1TXU2-1" }, "locus": { "chromosome": "12", "start_pos": 20035345, "end_pos": 20030252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083280.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083280.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074498.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074498.1" } ] } }, { "isoform_ac": "A0A4X1TXU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2/entry#A0A4X1TXU2-1", "sequence": { "sequence": "MEKWILKKIKYLQSGGLSASHYNYKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY", "length": 265, "header": "tr|A0A4X1TXU2-1|A0A4X1TXU2_PIG Isoform 1 of Proteasome activator complex subunit 3 OS=Sus scrofa OX=9823 GN=PSME3 PE=3 SV=1 CANONICAL=A0A4X1TXU2-1" }, "locus": { "chromosome": "12", "start_pos": 20034795, "end_pos": 20030252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078981.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078981.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071458.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071458.1" } ] } }, { "isoform_ac": "A0A8D1X9E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2/entry#A0A8D1X9E3-1", "sequence": { "sequence": "MASLLKVDQEVKLKVDSFRERITSEEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY", "length": 233, "header": "tr|A0A8D1X9E3-1|A0A4X1TXU2_PIG Computationally mapped isoform of Proteasome activator complex subunit 3 OS=Sus scrofa OX=9823 GN=PSME3 PE=3 SV=1 CANONICAL=A0A4X1TXU2-1" }, "locus": { "chromosome": "12", "start_pos": 20035345, "end_pos": 20030252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018924.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018924.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018419.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018419.3" } ] } }, { "isoform_ac": "A0A900QFT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2/entry#A0A900QFT4-1", "sequence": { "sequence": "MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY", "length": 243, "header": "tr|A0A900QFT4-1|A0A4X1TXU2_PIG Computationally mapped isoform of Proteasome activator complex subunit 3 OS=Sus scrofa OX=9823 GN=PSME3 PE=3 SV=1 CANONICAL=A0A4X1TXU2-1" }, "locus": { "chromosome": "12", "start_pos": 20035345, "end_pos": 20030252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041498.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041498.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047936.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047936.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 196, "start_aa": "Thr", "end_pos": 196, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr196", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1X9E3", "url": "https://www.uniprot.org/uniprotkb/A0A8D1X9E3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "proteasome activator complex", "id": "GO:0008537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008537", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2" } ], "pmid": "" }, { "name": "endopeptidase activator activity", "id": "GO:0061133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061133", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2" } ], "pmid": "" }, { "name": "MDM2/MDM4 family protein binding", "id": "GO:0097371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097371", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001237", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2" } ], "pmid": "" }, { "name": "regulation of proteasomal protein catabolic process", "id": "GO:0061136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061136", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TXU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2" }, { "id": "PF02252", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02252" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Proteasome activator PA28 C-terminal", "eco_id": "ECO_0000259", "start_pos": 120, "end_pos": 262, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TXU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXU2" }, { "id": "PF02251", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02251" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Proteasome activator PA28 N-terminal", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 80, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 196 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VEZ1-1", "uniprot_ac": "A0A4X1VEZ1", "uniprot_id": "A0A4X1VEZ1_PIG", "mass": { "chemical_mass": 174521.0, "monoisotopic_mass": 174521.0 }, "refseq": { "ac": "XP_020947899", "name": "ATP-binding cassette sub-family C member 9 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947899" }, "gene_names": [ { "name": "ABCC9", "type": "recommended", "evidence": [ { "id": "A0A4X1VEZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ] }, { "name": "ABCC9", "type": "synonym", "evidence": [ { "id": "XP_020947899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947899" } ] } ], "protein_names": [ { "name": "ATP binding cassette subfamily C member 9", "type": "synonym", "evidence": [ { "id": "A0A4X1VEZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1/entry#names_and_taxonomy" } ] }, { "name": "ATP-binding cassette sub-family C member 9 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_020947899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947899" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ABCC9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1", "locus": { "chromosome": "5", "start_pos": 51691595, "end_pos": 51536526, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000571", "url": "https://www.ensembl.org/id/ENSSSCG00000000571" } ] } } ], "crossref": [ { "id": "ENSSSCG00000000571", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000571", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03288", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03288", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03290", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03290", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18591", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18591", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18602", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18602", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100127449", "url": "https://www.ncbi.nlm.nih.gov/gene/100127449", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LLYALTX", "url": "https://omabrowser.org/oma/group/LLYALTX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1296025", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-382556", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-382556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5578775", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5578775", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020947899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947899", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AC87", "url": "https://www.uniprot.org/uniprotkb/A0A287AC87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AC87-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AC87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VEZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VG23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VG23-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VHS1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VHS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VHS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VHS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SR11", "url": "https://www.uniprot.org/uniprotkb/F1SR11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SR11-1", "url": "https://www.uniprot.org/uniprotkb/F1SR11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLSFCGNNISSYNIYDGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQSGWGVSDLRFCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTPSIWLAMYTAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETQNGTNNATGISEKLSSKEFLENSYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRSGESSLPFESCKKHTGVPPKTINRKQPGRYHLDSYEQSTRRLHPAETEDIAIKVTNGYFSWGSGLATLSNINIQIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQLEDEDEEEEEEEEEDDNMSTVMRLRTKMPWKTCWRYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYNIKNTGKTDQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALVPLGVAFYFIQKYFRVASKDLQELDDTTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPVLFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADLVIVMKRGNILEYDTPESLLAREDGVFASFVRADM", "length": 1549, "header": "tr|A0A4X1VEZ1-1|A0A4X1VEZ1_PIG Isoform 1 of ATP binding cassette subfamily C member 9 OS=Sus scrofa OX=9823 GN=ABCC9 PE=3 SV=1 CANONICAL=A0A4X1VEZ1-1" }, "isoforms": [ { "isoform_ac": "A0A287AC87-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1/entry#A0A287AC87-1", "sequence": { "sequence": "MSLSFCGNNISSYNIYDGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQSGWGVSDLRFCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTPSIWLAMYTAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETQNGTNNATGISEKLSSKEFLENSYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRSGESSLPFESCKKHTGVPPKTINRKQPGRYHLDSYEQSTRRLHPAETEDIAIKVTNGYFSWGSGLATLSNINIQIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQLEDEDEEEEEEEEEDDNMSTVMRLRTKMPWKTCWRYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYNIKNTGKTDQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALVPLGVAFYFIQKYFRVASKDLQELDDTTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPVLFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAIHTCELVDV", "length": 1513, "header": "tr|A0A287AC87-1|A0A4X1VEZ1_PIG Computationally mapped isoform of ATP binding cassette subfamily C member 9 OS=Sus scrofa OX=9823 GN=ABCC9 PE=3 SV=2 CANONICAL=A0A4X1VEZ1-1" }, "locus": { "chromosome": "5", "start_pos": 51691504, "end_pos": 51542135, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059132.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059132.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041578.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041578.2" } ] } }, { "isoform_ac": "A0A4X1VEZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1/entry#A0A4X1VEZ1-1", "sequence": { "sequence": "MSLSFCGNNISSYNIYDGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQSGWGVSDLRFCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTPSIWLAMYTAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETQNGTNNATGISEKLSSKEFLENSYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRSGESSLPFESCKKHTGVPPKTINRKQPGRYHLDSYEQSTRRLHPAETEDIAIKVTNGYFSWGSGLATLSNINIQIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQLEDEDEEEEEEEEEDDNMSTVMRLRTKMPWKTCWRYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYNIKNTGKTDQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALVPLGVAFYFIQKYFRVASKDLQELDDTTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPVLFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADLVIVMKRGNILEYDTPESLLAREDGVFASFVRADM", "length": 1549, "header": "tr|A0A4X1VEZ1-1|A0A4X1VEZ1_PIG Isoform 1 of ATP binding cassette subfamily C member 9 OS=Sus scrofa OX=9823 GN=ABCC9 PE=3 SV=1 CANONICAL=A0A4X1VEZ1-1" }, "locus": { "chromosome": "5", "start_pos": 51673246, "end_pos": 51542135, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056800.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056800.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055442.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055442.1" } ] } }, { "isoform_ac": "A0A4X1VG23-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1/entry#A0A4X1VG23-1", "sequence": { "sequence": "MSLSFCGNNISSYNIYDGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLGFGHHERKSCYKHS", "length": 149, "header": "tr|A0A4X1VG23-1|A0A4X1VEZ1_PIG Computationally mapped isoform of ATP binding cassette subfamily C member 9 OS=Sus scrofa OX=9823 GN=ABCC9 PE=3 SV=1 CANONICAL=A0A4X1VEZ1-1" }, "locus": { "chromosome": "5", "start_pos": 51553472, "end_pos": 51542135, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055869.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055869.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031623.2", "url": "https://www.ensembl.org/id/ENSSSCP00000031623.2" } ] } }, { "isoform_ac": "A0A4X1VHS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1/entry#A0A4X1VHS1-1", "sequence": { "sequence": "MSLSFCGNNISSYNIYDGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLGLCVSASGLESRGIFCRSKSVVDAVGMSHSSGASLQ", "length": 171, "header": "tr|A0A4X1VHS1-1|A0A4X1VEZ1_PIG Computationally mapped isoform of ATP binding cassette subfamily C member 9 OS=Sus scrofa OX=9823 GN=ABCC9 PE=3 SV=1 CANONICAL=A0A4X1VEZ1-1" }, "locus": { "chromosome": "5", "start_pos": 51551339, "end_pos": 51542135, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087424.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087424.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073189.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073189.1" } ] } }, { "isoform_ac": "F1SR11-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1/entry#F1SR11-1", "sequence": { "sequence": "MSLSFCGNNISSYNIYDGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQSGWGVSDLRFCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTPSIWLAMYTAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETQNGTNNATGISEKLSSKEFLENSYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRSGESSLPFESCKKHTGVPPKTINRKQPGRYHLDSYEQSTRRLHPAETEDIAIKVTNGYFSWGSGLATLSNINIQIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQLEDEDEEEEEEEEEDDNMSTVMRLRTKMPWKTCWRYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYNIKNTGKTDQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALVPLGVAFYFIQKYFRVASKDLQELDDTTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPVLFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSILDAGLVLVLSEGILVECDTVPNLLALKNGLFSTLVMTNK", "length": 1549, "header": "tr|F1SR11-1|A0A4X1VEZ1_PIG Computationally mapped isoform of ATP binding cassette subfamily C member 9 OS=Sus scrofa OX=9823 GN=ABCC9 PE=3 SV=3 CANONICAL=A0A4X1VEZ1-1" }, "locus": { "chromosome": "5", "start_pos": 51669557, "end_pos": 51542135, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000614.4", "url": "https://www.ensembl.org/id/ENSSSCT00000000614.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000600.3", "url": "https://www.ensembl.org/id/ENSSSCP00000000600.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SR11", "url": "https://www.uniprot.org/uniprotkb/F1SR11" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1296025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296025", "resource": "Reactome", "description": "ATP sensitive Potassium channels" }, { "id": "R-SSC-382556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-382556", "resource": "Reactome", "description": "ABC-family protein mediated transport" }, { "id": "R-SSC-5578775", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5578775", "resource": "Reactome", "description": "Ion homeostasis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BBT3-1", "protein_name": "ATP-binding cassette sub-family C member 9 isoform X1", "gene_name": "abcc9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALSFCGNDRDSNAYSVDNGVLDNGCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNMRWILTFTLLFVHVCEIAEGIVSNTQMESNHLHLFMPAFMGFIAATTSVVYYHNIETANFPKLLLALFIYWILAFITKMIKLWKFAEASLGVQHLRFCITALLVVLYGLLMAVEINVIRVRKYVFFANPQRVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNPLIIGAHKRPIELKKIGKLPIAMRALTNYLRLKDSYEEQRQNTEDPEKSPSIWKSMYRAFGGSILLSSTFRYMADLLGFAGPLCISGIVEHLHNSTEIDRTNKTGNMTFGVYFMSSTELLQNTSVLAVLLFLALVLQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNMSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYYLLGNSALIGAGVILLLAPVQYLIATKLADIQKSTLDYSTDRLKKTTEILKGIKLLKLYAWENIFCDRVEETRGKELTSLKTFALHTSMSIFMNAAIPIAAVLATFVTHAYIEEDRLSPAKAFASLALFHILVTPLFLLSTVVRFAVKALVSVQKLSEFLQSDEIGDDSWRNGDMCMSLEVGKKYKYQGDTKAINRKGRYRMDNYEQPVRRQLRPSETEDVAVQVNDGFFTWGSNLSTLSDINIRIPTGQLTMIVGQVGCGKSSLLLAMLGEMQTISGKVYWSKLPDCEILFDGNISGHDMELSHEERSKNRYSVAYATQKSWLLNATVEENITFGSPFNKQRYKAVIDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLIHADWIIAMKDGSVLREGTLKDIQTHDVELYEHWKTLMNRQDQELEKDTDLESQTTLERKTLRRAFYSREAKNHVDDEDEEEEVEEEDDDNMSTTTSRRSKIPWKMCCCYLSSGGFLMVFLMVSSKLAKHSVMVAIDYWLAAWTSSNPHNQSFVNSSFNHTLNDDATQIAEHRSYVPVFIILCAAAIALCLITSLTVEFLGVAAATNLHHNLLNKIIHAPIRFFDVTPLGQILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGVIAFVTPAFLIALVPLAVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHEARFKQRMLELTDTNNTAYLFLSAANRWLEVRTDYLGAVIVLTAAVAAIWSTSPSGLVGLGLTYALTLTNYLNWVVRNLADLEVQMAAVKKVNSFLSTESENYEGSMDVSQVPEDWPQHGEITIHDLCVRYDSMLKPVLKHVNAHINPGQKVGICGRTGSGKSSLSLAFFNMVDVFEGKIVIDGIDICKLPLQTLRSRLSIILQDPVLFSGSIRLNLDPERTCTDDRLWEALEIAQLKNMVKALPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHLVSSILEAEQVLVFSSGILVENDSAINLLAQEDSLFGILVRTHK", "length": 1583 }, "evidence": [ { "id": "A0A4X1VEZ1", "url": "https://omabrowser.org/oma/group/A0A4X1VEZ1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0YHU1-1", "protein_name": "ATP binding cassette subfamily C member 9", "gene_name": "ABCC9", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLAFCGNDNASAYNITAGVLRNVCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFTLLFVHVCEIAEGIVSDTQMKSRHLHLFLPAIIGFVAATVSIVYYHNIETSNFPKLLLALFLYWIMAFVTKTIKFVRYCQDGVSFSQLRFCITGIMVILYGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPVDLKAIGKLPIAMRALTNYVCLKEAYEEQKKKVADQPNRSPSIWLAMYSAFGRPILLSSTFRYLADLLGFAGPLCISGIVQGFQNTTNGTNTTEKDPSNSYLSSEEFFRNVYVLAVLLFLALILQRTFLQASYYVTTETGINLRGALLAMIYDKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGIILLHHLLGVSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKNVEETRMKELTSLKTFALHTSLSIFMNAAIPIAAVLATFVTYAYSNDEPLQPAQAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGDDSWRGGDNSVAYESCKKHTGLHTKAINRRQPLRYQLENYEQSSRRQTRPVETDDIAIKVTNGYFSWGSGLATLSNINIRIPTGQMTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSLEASRSKNRYSVAYAAQKPWLLNATVEENIIFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNVVFLDDPFSALDIHLSDHLMQEGILKFLQEDKRTLVLVTHKLQYLPHADWIIAMKDGMVLREGTLKDIQNNDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYPRESKAQLEDEDEEEEEEEDEDDNMSTVLRLRTKMPWKTCWRYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSTDNRKEFGNADVQNTGKTYHVAVFGILSGAGIVLCLITSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDMTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPWFLVALMPLGIAFYFIQKYFRVASKDLQELDDSTLLPLLCHFSETAEGLTTIRAFRHESRFKQRMLELTDTNNIAYLFLSAANIWLEVRMDYLGACIVLTAAITSITEGPDSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVHSFLNMESENYDGYLDASQVPKDWPQEGEIKIENLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGRIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDTLWEALEIAQLKNMVKSLPGGLDAMVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADLVIVMKRGNILEYDTPENLLSQEDGIFASFVRADM", "length": 1558 }, "evidence": [ { "id": "A0A4X1VEZ1", "url": "https://omabrowser.org/oma/group/A0A4X1VEZ1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O60706-1", "protein_name": "ATP-binding cassette sub-family C member 9", "gene_name": "ABCC9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLSFCGNNISSYNINDGVLQNSCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYCQSGLDISNLRFCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETQNGTNNTTGISETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGDDSWRTGESSLPFESCKKHTGVQPKTINRKQPGRYHLDSYEQSTRRLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSRNRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWRYLTSGGFFLLILMIFSKLLKHSVIVAIDYWLATWTSEYSINNTGKADQTYYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALLPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIMDAGLVLVFSEGILVECDTVPNLLAHKNGLFSTLVMTNK", "length": 1549 }, "evidence": [ { "id": "A0A4X1VEZ1", "url": "https://omabrowser.org/oma/group/A0A4X1VEZ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70170-1", "protein_name": "ATP-binding cassette sub-family C member 9", "gene_name": "Abcc9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLSFCGNNISSYNIYYGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSHRASRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQLGWGVSDLRFCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKAIGKLPIAMRAVTNYVCLKEAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNEKTNTTREMFPETLSSKEFLENAHVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRAGEGTLPFESCKKHTGVQSKPINRKQPGRYHLDSYEQARRLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWNNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSPFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEEDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINHPGKADQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALAPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIVDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK", "length": 1546 }, "evidence": [ { "id": "A0A4X1VEZ1", "url": "https://omabrowser.org/oma/group/A0A4X1VEZ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63563-1", "protein_name": "ATP-binding cassette sub-family C member 9", "gene_name": "Abcc9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSFCGNNISSYNIYHGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSQRASRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQLGWGMSDLRFCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKAIGKLPIAMRAVTNYVCLKEAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNEPKNNTTRFSETLSSKEFLENAHVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRTGEGTLPFESCKKHTGVQSKPINRKQPGRYHLDNYEQARRLRPAETEDVAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWNNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSSFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINDPGKADQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLIALAPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIMDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK", "length": 1545 }, "evidence": [ { "id": "A0A4X1VEZ1", "url": "https://omabrowser.org/oma/group/A0A4X1VEZ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8LGU1-1", "protein_name": "ABC transporter C family member 8", "gene_name": "ABCC8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAFIGSLPWCDVELNLASSCFQRTAIAFVNLLFLCIFYLFLIASCVSTHFIVRGRKKGWIFVAVAICCAITSFIFLGVGLNSLIHGGNDVTEISWVACFVEGIIWVSLAVSLLVNGSKWVNILVSVWWVSFALLDLVAKSGILLQGNGIRILDILTLPMSLLLLLCSWMNLRSSSAAAQDCSVTGLSDPLLTKNPRKESARLATAGFFSILSFSWMNPLLSLGFKKPLSPEDIPSVVPEDEAQLAYKKFSQAWDTLLGDESSTKERNLVFRAVVKVYFKENIFIAVFAFLRTFAVVSLPLMLYVFVDYANSDHRDLRNGFFNLACLVMLKLVESLTMRHWYFASRRSGMRIRSALMVAAYKKQLKLSSLGRKRHSSGEIVNYIAVDAYRMGEFLWWFHSGWSLSLQLLLSTAVLFGVVGAGAFPGLILLLLCGLLNLPFAKMLQNCQTQFMIAQDKRLRSTSEILNSMKVIKLQSWEDEFKKKIESCRDDEFTWLAKAQLTKAFGSFLYWMSPTIVSSVVFLGCALLKSAPLNASTIFTVLATLRVMSEPVKIIPDAISAIIQGNVSFQRLNNFLLDDELKMDEIERSGLDASGTAVDIQVGNFGWEPETKIPTLRNIHLEIKHGQKVAVCGPVGAGKSSLLHAVLGEIPKVSGTVKVFGSIAYVSQTSWIQSGTIRDNILYGKPMESRRYNAAIKACALDKDMNGFGHGDLTEIGQRGINLSGGQKQRIQLARAVYADADVYLLDDPFSAVDAHTAGVLFHKCVEDSLKEKTVILVTHQVEFLSEVDQILVMEEGTITQSGKYEELLMMGTAFQQLVNAHNDAVTVLPLASNESLGDLRKEGKDREIRNMTVVEKIEEEIEKTDIPGVQLTQEEEKESGYVGMKPFLDYIGVSRGWCLLWSSVLGQVGFVVFQAASTYWLAFAIGIPKITNTMLIGVYSIISTLSAGFVYARAITTAHLGLKASKAFFSGFTNAVFKAPMLFFDSTPVGRILTRASSDLNVLDYDVPFAFIFVVAPAVELTAALLIMTYVTWQVIIIALLALAATKVVQDYYLASARELIRINGTTKAPVMNYAAETSLGVVTIRAFGTAERFFKNYLNLVDADAVLFFLSNAAMEWVILRIETLQNVTLFTCALLLILIPKGYIAPGLVGLSLSYALTLTQTQVFLTRWYCTLSNSIISVERIKQYMNIPEEPPAIIDDKRPPSSWPSNGTIHLQELKIRYRPNAPLVLKGISCTFREGTRVGVVGRTGSGKSTLISALFRLVEPASGCILIDGIDISKIGLKDLRMKLSIIPQEPTLFRGCIRTNLDPLGVYSDDEIWKALEKCQLKTTISNLPNKLDSSVSDEGENWSVGQRQLFCLGRVLLKRNKILVLDEATASIDSATDAIIQRIIREEFADCTVITVAHRVPTVIDSDMVMVLSFGDLVEYNEPSKLMETDSYFSKLVAEYWASCRGNSSQNLQL", "length": 1464 }, "evidence": [ { "id": "A0A4X1VEZ1", "url": "https://omabrowser.org/oma/group/A0A4X1VEZ1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "sulfonylurea receptor activity", "id": "GO:0008281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008281", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "inward rectifying potassium channel", "id": "GO:0008282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008282", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cardiac conduction", "id": "GO:0061337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061337", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "response to ATP", "id": "GO:0033198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033198", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" }, { "name": "potassium ion transport", "id": "GO:0006813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006813", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1448, "end_pos": 1450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 735, "end_pos": 737, "annotation": "n_glycosylation_sequon" }, { "start_pos": 763, "end_pos": 765, "annotation": "n_glycosylation_sequon" }, { "start_pos": 769, "end_pos": 771, "annotation": "n_glycosylation_sequon" }, { "start_pos": 811, "end_pos": 813, "annotation": "n_glycosylation_sequon" }, { "start_pos": 966, "end_pos": 968, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1VEZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" }, { "id": "PS50929", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50929" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transmembrane type-1", "eco_id": "ECO_0000259", "start_pos": 306, "end_pos": 597, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1VEZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEZ1" }, { "id": "PS50893", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 672, "end_pos": 912, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1448, "end_pos": 1450 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 735, "end_pos": 737 }, { "start_pos": 763, "end_pos": 765 }, { "start_pos": 769, "end_pos": 771 }, { "start_pos": 811, "end_pos": 813 }, { "start_pos": 966, "end_pos": 968 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1USC1-1", "uniprot_ac": "A0A4X1USC1", "uniprot_id": "A0A4X1USC1_PIG", "mass": { "chemical_mass": 24648.0, "monoisotopic_mass": 24648.0 }, "refseq": { "ac": "NP_001230628", "name": "small nuclear ribonucleoprotein-associated protein N", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230628" }, "gene_names": [ { "name": "SNRPN", "type": "recommended", "evidence": [ { "id": "A0A4X1USC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ] }, { "name": "SNRPN", "type": "synonym", "evidence": [ { "id": "NP_001230628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230628" } ] } ], "protein_names": [ { "name": "Small nuclear ribonucleoprotein-associated protein", "type": "recommended", "evidence": [ { "id": "A0A4X1USC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1/entry#names_and_taxonomy" } ] }, { "name": "small nuclear ribonucleoprotein-associated protein N", "type": "synonym", "evidence": [ { "id": "NP_001230628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230628" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SNRPN", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1", "locus": {} } ], "crossref": [ { "id": "A0A4X1USC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1USC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000028124", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000028124", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01717", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01717", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626432", "url": "https://www.ncbi.nlm.nih.gov/gene/100626432", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626432", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626432", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGTTKMV", "url": "https://omabrowser.org/oma/group/MGTTKMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1USC1", "url": "https://www.orthodb.org/?gene=A0A4X1USC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14508", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14508", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14508:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14508:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230628", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1USC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LBT8", "url": "https://www.uniprot.org/uniprotkb/I3LBT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LBT8-1", "url": "https://www.uniprot.org/uniprotkb/I3LBT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPTPVGRATPPPGIMAPPPGMRPPMGPPIGLPPTRGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP", "length": 240, "header": "tr|A0A4X1USC1-1|A0A4X1USC1_PIG Isoform 1 of Small nuclear ribonucleoprotein-associated protein OS=Sus scrofa OX=9823 GN=SNRPN PE=3 SV=1 CANONICAL=A0A4X1USC1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1USC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1/entry#A0A4X1USC1-1", "sequence": { "sequence": "MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPTPVGRATPPPGIMAPPPGMRPPMGPPIGLPPTRGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP", "length": 240, "header": "tr|A0A4X1USC1-1|A0A4X1USC1_PIG Isoform 1 of Small nuclear ribonucleoprotein-associated protein OS=Sus scrofa OX=9823 GN=SNRPN PE=3 SV=1 CANONICAL=A0A4X1USC1-1" }, "locus": { "chromosome": "AEMK02000602.1", "start_pos": 115364, "end_pos": 108551, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047557.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047557.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034400.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034400.2" } ] } }, { "isoform_ac": "I3LBT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1/entry#I3LBT8-1", "sequence": { "sequence": "MLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPTPVGRATPPPGIMAPPPGMRPPMGPPIGLPPTRGTPIGMPPPGMRPPPPGIRGKWVHMFSVVLAMSLNISMFFFCVFFFLFS", "length": 250, "header": "tr|I3LBT8-1|A0A4X1USC1_PIG Computationally mapped isoform of Small nuclear ribonucleoprotein-associated protein OS=Sus scrofa OX=9823 GN=SNRPN PE=3 SV=3 CANONICAL=A0A4X1USC1-1" }, "locus": { "chromosome": "AEMK02000602.1", "start_pos": 113918, "end_pos": 108615, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029603.4", "url": "https://www.ensembl.org/id/ENSSSCT00000029603.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021510.3", "url": "https://www.ensembl.org/id/ENSSSCP00000021510.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 177, "start_aa": "Thr", "end_pos": 177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr177", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LBT8", "url": "https://www.uniprot.org/uniprotkb/I3LBT8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626432", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626432", "resource": "KEGG Pathway" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-SSC-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" }, { "id": "R-SSC-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "P63162-1", "protein_name": "Small nuclear ribonucleoprotein-associated protein N", "gene_name": "SNRPN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP", "length": 240 }, "evidence": [ { "id": "A0A4X1USC1", "url": "https://omabrowser.org/oma/group/A0A4X1USC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P63163-1", "protein_name": "Small nuclear ribonucleoprotein-associated protein N", "gene_name": "Snrpn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP", "length": 240 }, "evidence": [ { "id": "A0A4X1USC1", "url": "https://omabrowser.org/oma/group/A0A4X1USC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P63164-1", "protein_name": "Small nuclear ribonucleoprotein-associated protein N", "gene_name": "Snrpn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP", "length": 240 }, "evidence": [ { "id": "A0A4X1USC1", "url": "https://omabrowser.org/oma/group/A0A4X1USC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q17QN3-1", "protein_name": "Small nuclear ribonucleoprotein-associated protein N", "gene_name": "SNRPN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTAPTPVGRATPPPGIMAPPPGMRPPMGPPIGLPPTRGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP", "length": 240 }, "evidence": [ { "id": "A0A4X1USC1", "url": "https://omabrowser.org/oma/group/A0A4X1USC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" }, { "name": "snRNP binding", "id": "GO:0070990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070990", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" }, { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" }, { "name": "U4 snRNP", "id": "GO:0005687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005687", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1USC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USC1" }, { "id": "PS52002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sm", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 86, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 177 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VV61-1", "uniprot_ac": "A0A4X1VV61", "uniprot_id": "A0A4X1VV61_PIG", "mass": { "chemical_mass": 67596.0, "monoisotopic_mass": 67596.0 }, "refseq": { "ac": "XP_020934812", "name": "calnexin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934812" }, "gene_names": [ { "name": "CANX", "type": "recommended", "evidence": [ { "id": "A0A4X1VV61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ] }, { "name": "CANX", "type": "synonym", "evidence": [ { "id": "XP_020934812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934812" } ] } ], "protein_names": [ { "name": "Calnexin", "type": "recommended", "evidence": [ { "id": "A0A4X1VV61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61/entry#names_and_taxonomy" } ] }, { "name": "calnexin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020934812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934812" } ] } ], "function": [ { "annotation": "Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZLE4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLE4#function" }, { "database": "UniProtKB", "id": "ARBA00037453", "url": "https://www.uniprot.org/uniprotkb/ARBA00037453#function" }, { "database": "UniProtKB", "id": "A0A287AXF5", "url": "https://www.uniprot.org/uniprotkb/A0A287AXF5#function" }, { "database": "UniProtKB", "id": "ARBA00053392", "url": "https://www.uniprot.org/uniprotkb/ARBA00053392#function" }, { "database": "UniProtKB", "id": "A0A8D1EGJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8D1EGJ2#function" }, { "database": "UniProtKB", "id": "A0A8W4FIB6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIB6#function" }, { "database": "UniProtKB", "id": "A0A287ASN5", "url": "https://www.uniprot.org/uniprotkb/A0A287ASN5#function" }, { "database": "UniProtKB", "id": "F1S441", "url": "https://www.uniprot.org/uniprotkb/F1S441#function" }, { "database": "UniProtKB", "id": "A0A4X1VV67", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV67#function" }, { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CANX", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61", "locus": { "chromosome": "2", "start_pos": 78879033, "end_pos": 78915827, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014020", "url": "https://www.ensembl.org/id/ENSSSCG00000014020" } ] } } ], "crossref": [ { "id": "A0A4X1VV61", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1VV61", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014020", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014020", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100519184", "url": "https://www.ncbi.nlm.nih.gov/gene/100519184", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001580", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001580", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1VV61", "url": "https://www.orthodb.org/?gene=A0A4X1VV61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11073", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11073", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11073:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11073:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00262", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00262", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2132295", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8984722", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8984722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-901042", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-901042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9020956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9020956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9768727", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9768727", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983170", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020934812", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934812", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZLE4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZLE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASN5", "url": "https://www.uniprot.org/uniprotkb/A0A287ASN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ASN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXF5", "url": "https://www.uniprot.org/uniprotkb/A0A287AXF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VV61-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VV67", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VV67-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1EGJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8D1EGJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1EGJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1EGJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIB6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S441", "url": "https://www.uniprot.org/uniprotkb/F1S441", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S441-1", "url": "https://www.uniprot.org/uniprotkb/F1S441-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGKWLLCMLLVLGTAVVQAHDGHDDDVIDIEDDLDDVIEEVEDSKPKPDTSAPPSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLLSRAKHHAISTKLNKPFIFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQAVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPDAVKPDDWDEDAPAKIPDEEATKPIGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELWSMTSDIFFDNFIICGDRRVVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQASPVEYKKTDAPQPDVKEEEEEKEEEKEKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE", "length": 593, "header": "tr|A0A4X1VV61-1|A0A4X1VV61_PIG Isoform 1 of Calnexin OS=Sus scrofa OX=9823 GN=CANX PE=1 SV=1 CANONICAL=A0A4X1VV61-1" }, "isoforms": [ { "isoform_ac": "A0A286ZLE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61/entry#A0A286ZLE4-1", "sequence": { "sequence": "MEGKWLLCMLLVLGTAVVQAHDGHDDDVIDIEDDLDDVIEEVEDSKPKPDTSAPPSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLLSRAKHHAISTKLNKPFIFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQAVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPDAVKPDDWDEDAPAKIPDEEATKPIGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELWSMTSDIFFDNFIICGDRRVVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQASPVEYKKTDAPQPDVKEEEEEKEEEKEKGDEEEEGEEKLGG", "length": 551, "header": "tr|A0A286ZLE4-1|A0A4X1VV61_PIG Computationally mapped isoform of Calnexin OS=Sus scrofa OX=9823 GN=CANX PE=1 SV=2 CANONICAL=A0A4X1VV61-1" }, "locus": { "chromosome": "2", "start_pos": 78896778, "end_pos": 78881401, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058492.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058492.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032261.3", "url": "https://www.ensembl.org/id/ENSSSCP00000032261.3" } ] } }, { "isoform_ac": "A0A287ASN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61/entry#A0A287ASN5-1", "sequence": { "sequence": "MEGKWLLCMLLVLGTAVVQAHDGHDDDVIDIEDDLDDVIEEVEDSKPKPDTSAPPSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLLSRAKHHAISTKLNKPFIFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQAVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPDAVKPDDWDEDAPAKIPDEEATKPIGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELWSMTSDIFFDNFIICGDRRVVDDWANDGWGLKKAADGAAEVCTFLQKDKKRKKRKEILCSLIPEVKGTFAGD", "length": 499, "header": "tr|A0A287ASN5-1|A0A4X1VV61_PIG Computationally mapped isoform of Calnexin OS=Sus scrofa OX=9823 GN=CANX PE=1 SV=2 CANONICAL=A0A4X1VV61-1" }, "locus": { "chromosome": "2", "start_pos": 78896778, "end_pos": 78886761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041740.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041740.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047106.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047106.2" } ] } }, { "isoform_ac": "A0A287AXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61/entry#A0A287AXF5-1", "sequence": { "sequence": "MEGKWLLCMLLVLGTAVVQAHDGHDDDVIDIEDDLDDVIEEVEDSKPKPDTSAPPSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGSSEVELGSGTFFCCLAGKWEVDEMKETKLPGDKGLVLLSRAKHHAISTKLNKPFIFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQAVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPDAVKPDDWDEDAPAKIPDEEATKPIGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELWSMTSDIFFDNFIICGDRRVVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQASPVEYKKTDAPQPDVKEEEEEKEEEKEKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE", "length": 610, "header": "tr|A0A287AXF5-1|A0A4X1VV61_PIG Computationally mapped isoform of Calnexin OS=Sus scrofa OX=9823 GN=CANX PE=1 SV=3 CANONICAL=A0A4X1VV61-1" }, "locus": { "chromosome": "2", "start_pos": 78896778, "end_pos": 78881355, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063958.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063958.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048577.3", "url": "https://www.ensembl.org/id/ENSSSCP00000048577.3" } ] } }, { "isoform_ac": "A0A4X1VV61-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61/entry#A0A4X1VV61-1", "sequence": { "sequence": "MEGKWLLCMLLVLGTAVVQAHDGHDDDVIDIEDDLDDVIEEVEDSKPKPDTSAPPSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLLSRAKHHAISTKLNKPFIFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQAVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPDAVKPDDWDEDAPAKIPDEEATKPIGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELWSMTSDIFFDNFIICGDRRVVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQASPVEYKKTDAPQPDVKEEEEEKEEEKEKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE", "length": 593, "header": "tr|A0A4X1VV61-1|A0A4X1VV61_PIG Isoform 1 of Calnexin OS=Sus scrofa OX=9823 GN=CANX PE=1 SV=1 CANONICAL=A0A4X1VV61-1" }, "locus": { "chromosome": "2", "start_pos": 78896778, "end_pos": 78881355, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040961.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040961.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034670.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034670.2" } ] } }, { "isoform_ac": "A0A4X1VV67-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61/entry#A0A4X1VV67-1", "sequence": { "sequence": "MEGKWLLCMLLVLGTAVVQAHDGHDDDVIDIEDDLDDVIEEVEDSKPKPDTSAPPSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQAVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPDAVKPDDWDEDAPAKIPDEEATKPIGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELWSMTSDIFFDNFIICGDRRVVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQASPVEYKKTDAPQPDVKEEEEEKEEEKEKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE", "length": 517, "header": "tr|A0A4X1VV67-1|A0A4X1VV67_PIG Computationally mapped isoform of Calnexin OS=Sus scrofa OX=9823 GN=CANX PE=1 SV=1 CANONICAL=A0A4X1VV61-1" }, "locus": { "chromosome": "2", "start_pos": 78896778, "end_pos": 78881355, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043326.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043326.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045209.1", "url": "https://www.ensembl.org/id/ENSSSCP00000045209.1" } ] } }, { "isoform_ac": "A0A8D1EGJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61/entry#A0A8D1EGJ2-1", "sequence": { "sequence": "MEGKWLLCMLLVLGTAVVQAHDGHDDDVIDIEDDLDDVIEEVEDSKPKPDTSAPPSPKVTYKAPVPTGEVYFADSFDRGTLSGYHVNKMDSFLDIILHNKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQAVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPDAVKPDDWDEDAPAKIPDEEATKPIGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELWSMTSDIFFDNFIICGDRRVVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQASPVEYKKTDAPQPDVKEEEEEKEEEKEKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEVIRGESIFCISSNSSEATFK", "length": 502, "header": "tr|A0A8D1EGJ2-1|A0A4X1VV61_PIG Computationally mapped isoform of Calnexin OS=Sus scrofa OX=9823 GN=CANX PE=1 SV=1 CANONICAL=A0A4X1VV61-1" }, "locus": { "chromosome": "2", "start_pos": 78896778, "end_pos": 78884624, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075096.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075096.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060563.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060563.1" } ] } }, { "isoform_ac": "A0A8W4FIB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61/entry#A0A8W4FIB6-1", "sequence": { "sequence": "MEGKWLLCMLLVLGTAVVQAHDGHDDDVIDIEDDLDDVIEEVEDSKPKPDTSAPPSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLLSRAKHHAISTKLNKPFIFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQAVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPDAVKPDDWDEDAPAKIPDEEATKPIGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQASPVEYKKTDAPQPDVKEEEEEKEEEKEKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE", "length": 521, "header": "tr|A0A8W4FIB6-1|A0A4X1VV61_PIG Computationally mapped isoform of Calnexin OS=Sus scrofa OX=9823 GN=CANX PE=1 SV=1 CANONICAL=A0A4X1VV61-1" }, "locus": { "chromosome": "2", "start_pos": 78896778, "end_pos": 78881355, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094883.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094883.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079188.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079188.1" } ] } }, { "isoform_ac": "F1S441-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61/entry#F1S441-1", "sequence": { "sequence": "MEGKWLLCMLLVLGTAVVQAHDGHDDDVIDIEDDLDDVIEEVEDSKPKPDTSAPPSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLLSRAKHHAISTKLNKPFIFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQAVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPDAVKPDDWDEDAPAKIPDEEATKPIGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELWSMTSDIFFDNFIICGDRRVVDDWANDGWGLKKAADGAAEKQASPVEYKKTDAPQPDVKEEEEEKEEEKEKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE", "length": 553, "header": "tr|F1S441-1|A0A4X1VV61_PIG Computationally mapped isoform of Calnexin OS=Sus scrofa OX=9823 GN=CANX PE=1 SV=2 CANONICAL=A0A4X1VV61-1" }, "locus": { "chromosome": "2", "start_pos": 78896778, "end_pos": 78881355, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015315.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015315.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014907.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014907.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZLE4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLE4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2132295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "resource": "Reactome", "description": "MHC class II antigen presentation" }, { "id": "R-SSC-8984722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8984722", "resource": "Reactome", "description": "Interleukin-35 Signalling" }, { "id": "R-SSC-901042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-901042", "resource": "Reactome", "description": "Calnexin/calreticulin cycle" }, { "id": "R-SSC-9020956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9020956", "resource": "Reactome", "description": "Interleukin-27 signaling" }, { "id": "R-SSC-9768727", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9768727", "resource": "Reactome", "description": "Regulation of CDH1 posttranslational processing and trafficking to plasma membrane" }, { "id": "R-SSC-983170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983170", "resource": "Reactome", "description": "Antigen Presentation: Folding, assembly and peptide loading of class I MHC" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" }, { "name": "melanosome membrane", "id": "GO:0033162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033162", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" }, { "name": "endoplasmic reticulum quality control compartment", "id": "GO:0044322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044322", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" }, { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VV61", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VV61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 582, "end_pos": 584 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1ULB2-1", "uniprot_ac": "A0A4X1ULB2", "uniprot_id": "A0A4X1ULB2_PIG", "mass": { "chemical_mass": 21921.0, "monoisotopic_mass": 21921.0 }, "refseq": { "ac": "XP_020939001", "name": "guanylate kinase isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939001" }, "gene_names": [ { "name": "GUK1", "type": "recommended", "evidence": [ { "id": "A0A4X1ULB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2" } ] }, { "name": "GUK1", "type": "synonym", "evidence": [ { "id": "XP_020939001", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939001" } ] } ], "protein_names": [ { "name": "Guanylate kinase", "type": "recommended", "evidence": [ { "id": "A0A4X1ULB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2/entry#names_and_taxonomy" } ] }, { "name": "2.7.4.8", "type": "synonym", "evidence": [ { "id": "A0A4X1ULB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2/entry#names_and_taxonomy" } ] }, { "name": "GMP kinase", "type": "synonym", "evidence": [ { "id": "A0A4X1ULB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2/entry#names_and_taxonomy" } ] }, { "name": "guanylate kinase isoform X3", "type": "synonym", "evidence": [ { "id": "XP_020939001", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939001" } ] } ], "function": [ { "annotation": "Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP and indirectly, cyclic GMP (cGMP). Involved in the cGMP metabolism in photoreceptors.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV71", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV71#function" }, { "database": "UniProtKB", "id": "ARBA00053219", "url": "https://www.uniprot.org/uniprotkb/ARBA00053219#function" }, { "database": "UniProtKB", "id": "A0A4X1ULB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2#function" }, { "database": "UniProtKB", "id": "F1S5R9", "url": "https://www.uniprot.org/uniprotkb/F1S5R9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ULB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GUK1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2", "locus": {} } ], "crossref": [ { "id": "A0A4X1ULB2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1ULB2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013990", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013990", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513720", "url": "https://www.ncbi.nlm.nih.gov/gene/100513720", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017665", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017665", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513720", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513720", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S5R9", "url": "https://www.orthodb.org/?gene=F1S5R9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23117:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23117:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-499943", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-499943", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9748787", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9748787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020939001", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939001", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20780", "url": "https://www.rhea-db.org/rhea/20780", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZV71", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZV71-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1ULB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1ULB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5R9", "url": "https://www.uniprot.org/uniprotkb/F1S5R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5R9-1", "url": "https://www.uniprot.org/uniprotkb/F1S5R9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGPRPVVLSGPSGAGKSTLLKKLLQEHSSIFGFSVSHTTRDPRPGEENGKDYYFVTREVMQRDIAAGDFIEHAEFSGNLYGTSKAAVRAVQAMNRICVLDVDLQGVRNIKKTDLQPIYIFVQPPSLDVLEQRLRQRNTETEESLAKRLAAAKADMESSKEPGLFDLIIINDSLDKAYWALKEALSEEIKKAQATGHS", "length": 198, "header": "tr|A0A4X1ULB2-1|A0A4X1ULB2_PIG Isoform 1 of Guanylate kinase OS=Sus scrofa OX=9823 GN=GUK1 PE=3 SV=1 CANONICAL=A0A4X1ULB2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZV71-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2/entry#A0A286ZV71-1", "sequence": { "sequence": "MSGPRPVVLSGPSGAGKSTLLKKLLQEHSSIFGFSVSHTTRDPRPGEENGKDYYFVTREVMQRDIAAGDFIEHAEFSGNLYGTSKAAVRAVQAMNRICVLDVDLQGVRNIKKTDLQPIYIFVQPPSLDVLEQRLRQRNTETEESLAKRLAAAKADMESSKEPGLFDLIIINDSLDKAYWALKEAGSAHLSQNPGIGLLPIFPCSPTMVGGPCLSPLPPCPFLGSFPHPTPFPQIKNYWFRVS", "length": 242, "header": "tr|A0A286ZV71-1|A0A4X1ULB2_PIG Computationally mapped isoform of Guanylate kinase OS=Sus scrofa OX=9823 GN=GUK1 PE=3 SV=2 CANONICAL=A0A4X1ULB2-1" }, "locus": { "chromosome": "2", "start_pos": 51257484, "end_pos": 51254147, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050790.2", "url": "https://www.ensembl.org/id/ENSSSCT00000050790.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035398.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035398.2" } ] } }, { "isoform_ac": "A0A4X1ULB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2/entry#A0A4X1ULB2-1", "sequence": { "sequence": "MSGPRPVVLSGPSGAGKSTLLKKLLQEHSSIFGFSVSHTTRDPRPGEENGKDYYFVTREVMQRDIAAGDFIEHAEFSGNLYGTSKAAVRAVQAMNRICVLDVDLQGVRNIKKTDLQPIYIFVQPPSLDVLEQRLRQRNTETEESLAKRLAAAKADMESSKEPGLFDLIIINDSLDKAYWALKEALSEEIKKAQATGHS", "length": 198, "header": "tr|A0A4X1ULB2-1|A0A4X1ULB2_PIG Isoform 1 of Guanylate kinase OS=Sus scrofa OX=9823 GN=GUK1 PE=3 SV=1 CANONICAL=A0A4X1ULB2-1" }, "locus": { "chromosome": "2", "start_pos": 51257227, "end_pos": 51254147, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060143.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060143.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050663.3", "url": "https://www.ensembl.org/id/ENSSSCP00000050663.3" } ] } }, { "isoform_ac": "F1S5R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2/entry#F1S5R9-1", "sequence": { "sequence": "MLRRPLAGLAAAALGRATSDGMSGPRPVVLSGPSGAGKSTLLKKLLQEHSSIFGFSVSHTTRDPRPGEENGKDYYFVTREVMQRDIAAGDFIEHAEFSGNLYGTSKAAVRAVQAMNRICVLDVDLQGVRNIKKTDLQPIYIFVQPPSLDVLEQRLRQRNTETEESLAKRLAAAKADMESSKEPGLFDLIIINDSLDKAYWALKEALSEEIKKAQATGHS", "length": 219, "header": "tr|F1S5R9-1|A0A4X1ULB2_PIG Computationally mapped isoform of Guanylate kinase OS=Sus scrofa OX=9823 GN=GUK1 PE=3 SV=5 CANONICAL=A0A4X1ULB2-1" }, "locus": { "chromosome": "2", "start_pos": 51257227, "end_pos": 51247736, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015281.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015281.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014875.5", "url": "https://www.ensembl.org/id/ENSSSCP00000014875.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV71", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV71" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513720", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513720", "resource": "KEGG Pathway" }, { "id": "R-SSC-499943", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-499943", "resource": "Reactome", "description": "Interconversion of nucleotide di- and triphosphates" }, { "id": "R-SSC-9748787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9748787", "resource": "Reactome", "description": "Azathioprine ADME" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GMP kinase activity", "id": "GO:0004385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004385", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ULB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ULB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "dGDP biosynthetic process", "id": "GO:0006185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006185", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ULB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2" } ], "pmid": "" }, { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ULB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ULB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ULB2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20780", "name": "", "equation": "GMP + ATP = GDP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20780", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20780" } ] }, { "id": "R-SSC-110133", "name": "(d)GDP + ADP <=> (d)GMP + ATP (GUK1)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-110133", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110133" } ] }, { "id": "R-SSC-73788", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-73788", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73788" } ] }, { "id": "R-SSC-9748949", "name": "GUK1 phosphorylates 6TGMP to 6TGDP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-9748970" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9748949", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9748949" } ] }, { "id": "R-SSC-9748963", "name": "GUK1 phosphorylates 6TdGMP to 6TdGDP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-9749031" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9748963", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9748963" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9748970", "participant_name": "6TGMP [cytosol]", "crossref": [ { "id": "180686", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9749031", "participant_name": "6TdGMP [cytosol]", "crossref": [ { "id": "180689", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1ULB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULB2" }, { "id": "PS50052", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50052" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate kinase-like", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 186, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TSJ1-1", "uniprot_ac": "A0A4X1TSJ1", "uniprot_id": "A0A4X1TSJ1_PIG", "mass": { "chemical_mass": 36216.0, "monoisotopic_mass": 36216.0 }, "refseq": {}, "gene_names": [ { "name": "ALDOC", "type": "recommended", "evidence": [ { "id": "A0A4X1TSJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1" } ] } ], "protein_names": [ { "name": "Fructose-bisphosphate aldolase", "type": "recommended", "evidence": [ { "id": "A0A4X1TSJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1/entry#names_and_taxonomy" } ] }, { "name": "4.1.2.13", "type": "synonym", "evidence": [ { "id": "A0A4X1TSJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B8Z2", "url": "https://www.uniprot.org/uniprotkb/A0A287B8Z2#function" }, { "database": "UniProtKB", "id": "ARBA00094270", "url": "https://www.uniprot.org/uniprotkb/ARBA00094270#function" }, { "database": "UniProtKB", "id": "A0A4X1TSJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1#function" }, { "database": "UniProtKB", "id": "A0A286ZWI1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWI1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ALDOC", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1", "locus": { "chromosome": "12", "start_pos": 44822780, "end_pos": 44827597, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017759", "url": "https://www.ensembl.org/id/ENSSSCG00000017759" } ] } } ], "crossref": [ { "id": "A0A4X1TSJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TSJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017759", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017759", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00948", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00948", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11627", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11627", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00274", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00274", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-70171", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70171", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-70263", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70263", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "14729", "url": "https://www.rhea-db.org/rhea/14729", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZWI1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZWI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B8Z2", "url": "https://www.uniprot.org/uniprotkb/A0A287B8Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B8Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B8Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TSJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TSJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPHSYPALSAEQKKELSDIALRIVAPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLFSADDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQDKGIVVGIKVDKGVVPLAGTDGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKISERTPSALAILENANVLARYASICQQVLAAVYKALNDHHVYLEGTLLKPNMVTPGHACPIKYSPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASLNLNAINRCPLPRPWALTFSYGRALQASALNAWRGQQDNAGAATEEFIKRAEVNGLAAQGKYEGGGEDGGAAAQSLYIANHAY", "length": 336, "header": "tr|A0A4X1TSJ1-1|A0A4X1TSJ1_PIG Isoform 1 of Fructose-bisphosphate aldolase OS=Sus scrofa OX=9823 GN=ALDOC PE=1 SV=1 CANONICAL=A0A4X1TSJ1-1" }, "isoforms": [ { "isoform_ac": "A0A286ZWI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1/entry#A0A286ZWI1-1", "sequence": { "sequence": "MPHSYPALSAEQKKELSDIALRIVAPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLFSADDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQDKGIVVGIKVDKGVVPLAGTDGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKISERTPSALAILENANVLARYASICQQVCVHNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTPGHACPIKYSPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASLNLNAINRCPLPRPWALTFSYGRALQASALNAWRGQQDNAGAATEEFIKRAEVNGLAAQGKYEGGGEDGGAAAQSLYIANHAY", "length": 368, "header": "tr|A0A286ZWI1-1|A0A4X1TSJ1_PIG Computationally mapped isoform of Fructose-bisphosphate aldolase OS=Sus scrofa OX=9823 GN=ALDOC PE=1 SV=2 CANONICAL=A0A4X1TSJ1-1" }, "locus": { "chromosome": "12", "start_pos": 44825774, "end_pos": 44823784, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065042.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065042.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036049.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036049.2" } ] } }, { "isoform_ac": "A0A287B8Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1/entry#A0A287B8Z2-1", "sequence": { "sequence": "MPELQQRQIQAASATYTTAHSNAGSLTHCARPGIEPATSWFLVGFINHCAMMGTPGSSFYVLSPSCRTVTMPHSYPALSAEQKKELSDIALRIVAPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLFSADDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQDKGIVVGIKVDKGVVPLAGTDGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKISERTPSALAILENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTPGHACPIKYSPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASLNLNAINRCPLPRPWALTFSYGRALQASALNAWRGQQDNAGAATEEFIKRAEVNGLAAQGKYEGGGEDGGAAAQSLYIANHAY", "length": 434, "header": "tr|A0A287B8Z2-1|A0A4X1TSJ1_PIG Computationally mapped isoform of Fructose-bisphosphate aldolase OS=Sus scrofa OX=9823 GN=ALDOC PE=1 SV=1 CANONICAL=A0A4X1TSJ1-1" }, "locus": { "chromosome": "12", "start_pos": 44825984, "end_pos": 44823784, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092113.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092113.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074656.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074656.1" } ] } }, { "isoform_ac": "A0A4X1TSJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1/entry#A0A4X1TSJ1-1", "sequence": { "sequence": "MPHSYPALSAEQKKELSDIALRIVAPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLFSADDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQDKGIVVGIKVDKGVVPLAGTDGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKISERTPSALAILENANVLARYASICQQVLAAVYKALNDHHVYLEGTLLKPNMVTPGHACPIKYSPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASLNLNAINRCPLPRPWALTFSYGRALQASALNAWRGQQDNAGAATEEFIKRAEVNGLAAQGKYEGGGEDGGAAAQSLYIANHAY", "length": 336, "header": "tr|A0A4X1TSJ1-1|A0A4X1TSJ1_PIG Isoform 1 of Fructose-bisphosphate aldolase OS=Sus scrofa OX=9823 GN=ALDOC PE=1 SV=1 CANONICAL=A0A4X1TSJ1-1" }, "locus": { "chromosome": "12", "start_pos": 44825774, "end_pos": 44823784, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019331.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019331.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018818.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018818.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 207, "start_aa": "Thr", "end_pos": 207, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr207", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWI1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWI1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-70171", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70171", "resource": "Reactome", "description": "Glycolysis" }, { "id": "R-SSC-70263", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70263", "resource": "Reactome", "description": "Gluconeogenesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "fructose-bisphosphate aldolase activity", "id": "GO:0004332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004332", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1" } ], "pmid": "" }, { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1" } ], "pmid": "" }, { "name": "fructose 1,6-bisphosphate metabolic process", "id": "GO:0030388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030388", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1" } ], "pmid": "" }, { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1" } ], "pmid": "" }, { "name": "gluconeogenesis", "id": "GO:0006094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14729", "name": "", "equation": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "14729", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14729" } ] }, { "id": "R-SSC-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, tertiary granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6798745", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798745" } ] }, { "id": "R-SSC-6798748", "name": "Exocytosis of secretory granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, secretory granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6798748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798748" } ] }, { "id": "R-SSC-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6800434" } ] }, { "id": "R-SSC-71495", "name": "Aldolase tetramers convert GA3P and DHAP to F1,6PP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-71495", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71495" } ] }, { "id": "R-SSC-71496", "name": "Aldolase tetramer cleaves F1,6PP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-71496", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71496" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 207 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1V930-1", "uniprot_ac": "A0A4X1V930", "uniprot_id": "A0A4X1V930_PIG", "mass": { "chemical_mass": 46523.0, "monoisotopic_mass": 46523.0 }, "refseq": {}, "gene_names": [ { "name": "LUC7L2", "type": "recommended", "evidence": [ { "id": "A0A4X1V930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930" } ] } ], "protein_names": [ { "name": "RNA-binding protein Luc7-like", "type": "recommended", "evidence": [ { "id": "A0A4X1V930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binds to RNA via its Arg/Ser-rich domain.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V930", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930#function" }, { "database": "UniProtKB", "id": "RU369106", "url": "https://www.uniprot.org/uniprotkb/RU369106#function" }, { "database": "UniProtKB", "id": "A0A287A3H0", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V930", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LUC7L2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930", "locus": { "chromosome": "18", "start_pos": 10268960, "end_pos": 10333156, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016509", "url": "https://www.ensembl.org/id/ENSSSCG00000016509" } ] } } ], "crossref": [ { "id": "A0A4X1V930", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1V930", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016509", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016509", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "102162486", "url": "https://www.ncbi.nlm.nih.gov/gene/102162486", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004882", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004882", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CPHELFP", "url": "https://omabrowser.org/oma/group/CPHELFP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1V930", "url": "https://www.orthodb.org/?gene=A0A4X1V930", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12375", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12375", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287A3H0", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V930", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V930-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V940", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V940", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V940-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V940-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QP16", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QP16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QP16-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QP16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1A6M4", "url": "https://www.uniprot.org/uniprotkb/A0A8D1A6M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1A6M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1A6M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1ETA0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1ETA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1ETA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1ETA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1YNJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8D1YNJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1YNJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1YNJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SR21", "url": "https://www.uniprot.org/uniprotkb/F1SR21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SR21-1", "url": "https://www.uniprot.org/uniprotkb/F1SR21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSGHSSRDRSRERSRRRSSKERFRDQDLASRDRDRNSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI", "length": 392, "header": "tr|A0A4X1V930-1|A0A4X1V930_PIG Isoform 1 of RNA-binding protein Luc7-like OS=Sus scrofa OX=9823 GN=LUC7L2 PE=1 SV=1 CANONICAL=A0A4X1V930-1" }, "isoforms": [ { "isoform_ac": "A0A287A3H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930/entry#A0A287A3H0-1", "sequence": { "sequence": "MPGILHKWKQGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSGHSSRDRSRERSRRRSSKERFRDQDLASRDRDRNSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI", "length": 382, "header": "tr|A0A287A3H0-1|A0A4X1V930_PIG Computationally mapped isoform of RNA-binding protein Luc7-like OS=Sus scrofa OX=9823 GN=LUC7L2 PE=1 SV=3 CANONICAL=A0A4X1V930-1" }, "locus": { "chromosome": "18", "start_pos": 10329715, "end_pos": 10272162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061653.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061653.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038514.3", "url": "https://www.ensembl.org/id/ENSSSCP00000038514.3" } ] } }, { "isoform_ac": "A0A4X1V930-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930/entry#A0A4X1V930-1", "sequence": { "sequence": "MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSGHSSRDRSRERSRRRSSKERFRDQDLASRDRDRNSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI", "length": 392, "header": "tr|A0A4X1V930-1|A0A4X1V930_PIG Isoform 1 of RNA-binding protein Luc7-like OS=Sus scrofa OX=9823 GN=LUC7L2 PE=1 SV=1 CANONICAL=A0A4X1V930-1" }, "locus": { "chromosome": "18", "start_pos": 10332784, "end_pos": 10272162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072085.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072085.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060258.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060258.1" } ] } }, { "isoform_ac": "A0A4X1V940-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930/entry#A0A4X1V940-1", "sequence": { "sequence": "MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSSKERFRDQDLASRDRDRNSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI", "length": 328, "header": "tr|A0A4X1V940-1|A0A4X1V930_PIG Computationally mapped isoform of RNA-binding protein Luc7-like OS=Sus scrofa OX=9823 GN=LUC7L2 PE=1 SV=1 CANONICAL=A0A4X1V930-1" }, "locus": { "chromosome": "18", "start_pos": 10332784, "end_pos": 10272162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056034.2", "url": "https://www.ensembl.org/id/ENSSSCT00000056034.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046577.1", "url": "https://www.ensembl.org/id/ENSSSCP00000046577.1" } ] } }, { "isoform_ac": "A0A5G2QP16-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930/entry#A0A5G2QP16-1", "sequence": { "sequence": "ITGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSGHSSRDRSRERSRRRSSKERFRDQDLASRDRDRNSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI", "length": 374, "header": "tr|A0A5G2QP16-1|A0A4X1V930_PIG Computationally mapped isoform of RNA-binding protein Luc7-like OS=Sus scrofa OX=9823 GN=LUC7L2 PE=1 SV=1 CANONICAL=A0A4X1V930-1" }, "locus": { "chromosome": "18", "start_pos": 10316784, "end_pos": 10272162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080082.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080082.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065810.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065810.2" } ] } }, { "isoform_ac": "A0A8D1A6M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930/entry#A0A8D1A6M4-1", "sequence": { "sequence": "RILHKKLTLLKLIYKCVYTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSGHSSRDRSRERSRRRSSKERFRDQDLASRDRDRNSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI", "length": 378, "header": "tr|A0A8D1A6M4-1|A0A4X1V930_PIG Computationally mapped isoform of RNA-binding protein Luc7-like OS=Sus scrofa OX=9823 GN=LUC7L2 PE=1 SV=1 CANONICAL=A0A4X1V930-1" }, "locus": { "chromosome": "18", "start_pos": 10316932, "end_pos": 10272162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052365.2", "url": "https://www.ensembl.org/id/ENSSSCT00000052365.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055451.2", "url": "https://www.ensembl.org/id/ENSSSCP00000055451.2" } ] } }, { "isoform_ac": "A0A8D1ETA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930/entry#A0A8D1ETA0-1", "sequence": { "sequence": "ITGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSGHSSRDRSRERSRRRSSKERFRDQDLASRDRDRNSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI", "length": 364, "header": "tr|A0A8D1ETA0-1|A0A4X1V930_PIG Computationally mapped isoform of RNA-binding protein Luc7-like OS=Sus scrofa OX=9823 GN=LUC7L2 PE=1 SV=1 CANONICAL=A0A4X1V930-1" }, "locus": { "chromosome": "18", "start_pos": 10316784, "end_pos": 10272162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067503.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067503.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073327.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073327.1" } ] } }, { "isoform_ac": "A0A8D1YNJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930/entry#A0A8D1YNJ3-1", "sequence": { "sequence": "ISAKYTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSGHSSRDRSRERSRRRSSKERFRDQDLASRDRDRNSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI", "length": 365, "header": "tr|A0A8D1YNJ3-1|A0A4X1V930_PIG Computationally mapped isoform of RNA-binding protein Luc7-like OS=Sus scrofa OX=9823 GN=LUC7L2 PE=1 SV=1 CANONICAL=A0A4X1V930-1" }, "locus": { "chromosome": "18", "start_pos": 10317209, "end_pos": 10272162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052423.2", "url": "https://www.ensembl.org/id/ENSSSCT00000052423.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043648.2", "url": "https://www.ensembl.org/id/ENSSSCP00000043648.2" } ] } }, { "isoform_ac": "F1SR21-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930/entry#F1SR21-1", "sequence": { "sequence": "MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSGHSSRDRSRERSRRRSSKERFRDQDLASRDRDRNSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI", "length": 359, "header": "tr|F1SR21-1|F1SR21_PIG Computationally mapped isoform of LUC7 like 2, pre-mRNA splicing factor OS=Sus scrofa OX=9823 GN=LUC7L2 PE=1 SV=4 CANONICAL=A0A4X1V930-1" }, "locus": { "chromosome": "18", "start_pos": 10332784, "end_pos": 10272162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017974.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017974.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017490.4", "url": "https://www.ensembl.org/id/ENSSSCP00000017490.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V940", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V940" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8J8XLZ3-1", "protein_name": "RNA-binding protein Luc7-like", "gene_name": "Luc7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPAYFNLQGSFRKAPHSPSRDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVSKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASRDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI", "length": 381 }, "evidence": [ { "id": "A0A4X1V930", "url": "https://omabrowser.org/oma/group/A0A4X1V930/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TNC4-1", "protein_name": "Putative RNA-binding protein Luc7-like 2", "gene_name": "Luc7l2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVSKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASRDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI", "length": 392 }, "evidence": [ { "id": "A0A4X1V930", "url": "https://omabrowser.org/oma/group/A0A4X1V930/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VVI1-1", "protein_name": "Putative RNA-binding protein Alsin2", "gene_name": "Alsin2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSAPSNKMSATDQMRAMLDQLMGTTRNGDERQLKFSDPRVCKSFLLDCCPHDILASTRMDLGECPKVHDLAFRADYESAAKTRDYYYDIEAMEHLQAFIADCDRRTDSAKQRLKETQEELTAEVAEKANAVHGLAEEIGKKLAKAEALGEAGEVEDSMELMKEIEELRAKKIKAEHEYRTSMPASTYQQQKLRVCEVCSAYLGIHDNDIRLADHFGGKLHLGFLTIREKLIELEKTAAPRKAELKRTGKMTDREDEGRGRNRYFVGGRELDRRSRVHRSRSRERQRNRDGDRERPNNGRGPEEKGSERPKEAADGPERAERAPDRGGRRDDRDNHGRDHRERERDGRRDRDRHGRNDRGRFGDRGGGGGGGGHHRDDRRRSRSRERSPRERRNFNHFRDGGGGGNGQRKRSYSRERNYRR", "length": 420 }, "evidence": [ { "id": "A0A4X1V930", "url": "https://omabrowser.org/oma/group/A0A4X1V930/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y383-1", "protein_name": "Putative RNA-binding protein Luc7-like 2", "gene_name": "LUC7L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI", "length": 392 }, "evidence": [ { "id": "A0A4X1V930", "url": "https://omabrowser.org/oma/group/A0A4X1V930/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V930", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V930", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V930", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V930", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V930", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splice site recognition", "id": "GO:0006376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006376", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V930", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V930" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UTE2-1", "uniprot_ac": "A0A4X1UTE2", "uniprot_id": "A0A4X1UTE2_PIG", "mass": { "chemical_mass": 51019.0, "monoisotopic_mass": 51019.0 }, "refseq": { "ac": "XP_020919669", "name": "heterogeneous nuclear ribonucleoprotein K isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919669" }, "gene_names": [ { "name": "HNRNPK", "type": "recommended", "evidence": [ { "id": "A0A4X1UTE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ] }, { "name": "HNRNPK", "type": "synonym", "evidence": [ { "id": "XP_020919669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919669" } ] } ], "protein_names": [ { "name": "Heterogeneous nuclear ribonucleoprotein K", "type": "recommended", "evidence": [ { "id": "A0A4X1UTE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2/entry#names_and_taxonomy" } ] }, { "name": "heterogeneous nuclear ribonucleoprotein K isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020919669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919669" } ] } ], "function": [ { "annotation": "One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest. As part of a ribonucleoprotein complex composed at least of ZNF827, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2#function" }, { "database": "UniProtKB", "id": "ARBA00045294", "url": "https://www.uniprot.org/uniprotkb/ARBA00045294#function" }, { "database": "UniProtKB", "id": "A0A287A699", "url": "https://www.uniprot.org/uniprotkb/A0A287A699#function" }, { "database": "UniProtKB", "id": "A0A287B646", "url": "https://www.uniprot.org/uniprotkb/A0A287B646#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HNRNPK", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2", "locus": {} } ], "crossref": [ { "id": "A0A4X1UTE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UTE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000022760", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022760", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22432", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22432", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22433", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22433", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22434", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22434", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100622191", "url": "https://www.ncbi.nlm.nih.gov/gene/100622191", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "A0A4X1UTE2", "url": "https://www.ebi.ac.uk/intact/interactors/id:A0A4X1UTE2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UTE2", "url": "https://www.orthodb.org/?gene=A0A4X1UTE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-4570464", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4570464", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72203", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72203", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020919669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919669", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A699", "url": "https://www.uniprot.org/uniprotkb/A0A287A699", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A699-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A699-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B646", "url": "https://www.uniprot.org/uniprotkb/A0A287B646", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B646-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B646-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UTE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPQSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF", "length": 464, "header": "tr|A0A4X1UTE2-1|A0A4X1UTE2_PIG Isoform 1 of Heterogeneous nuclear ribonucleoprotein K OS=Sus scrofa OX=9823 GN=HNRNPK PE=1 SV=1 CANONICAL=A0A4X1UTE2-1" }, "isoforms": [ { "isoform_ac": "A0A287A699-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2/entry#A0A287A699-1", "sequence": { "sequence": "METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPQSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQVEYQSDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSGKFF", "length": 463, "header": "tr|A0A287A699-1|A0A4X1UTE2_PIG Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein K OS=Sus scrofa OX=9823 GN=HNRNPK PE=1 SV=3 CANONICAL=A0A4X1UTE2-1" }, "locus": { "chromosome": "10", "start_pos": 30986683, "end_pos": 30978002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048080.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048080.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039325.3", "url": "https://www.ensembl.org/id/ENSSSCP00000039325.3" } ] } }, { "isoform_ac": "A0A287B646-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2/entry#A0A287B646-1", "sequence": { "sequence": "METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPQSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDVSIFNTKGMFNAFYVS", "length": 389, "header": "tr|A0A287B646-1|A0A4X1UTE2_PIG Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein K OS=Sus scrofa OX=9823 GN=HNRNPK PE=1 SV=3 CANONICAL=A0A4X1UTE2-1" }, "locus": { "chromosome": "10", "start_pos": 30985360, "end_pos": 30978002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064724.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064724.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051984.3", "url": "https://www.ensembl.org/id/ENSSSCP00000051984.3" } ] } }, { "isoform_ac": "A0A4X1UTE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2/entry#A0A4X1UTE2-1", "sequence": { "sequence": "METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPQSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF", "length": 464, "header": "tr|A0A4X1UTE2-1|A0A4X1UTE2_PIG Isoform 1 of Heterogeneous nuclear ribonucleoprotein K OS=Sus scrofa OX=9823 GN=HNRNPK PE=1 SV=1 CANONICAL=A0A4X1UTE2-1" }, "locus": { "chromosome": "10", "start_pos": 30986626, "end_pos": 30978002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025854.3", "url": "https://www.ensembl.org/id/ENSSSCT00000025854.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026450.3", "url": "https://www.ensembl.org/id/ENSSSCP00000026450.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A699", "url": "https://www.uniprot.org/uniprotkb/A0A287A699" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-4570464", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4570464", "resource": "Reactome", "description": "SUMOylation of RNA binding proteins" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-SSC-72203", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72203", "resource": "Reactome", "description": "Processing of Capped Intron-Containing Pre-mRNA" }, { "id": "R-SSC-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "lncRNA binding", "id": "GO:0106222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106222", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "podosome", "id": "GO:0002102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002102", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "random inactivation of X chromosome", "id": "GO:0060816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060816", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated heterochromatin formation", "id": "GO:0031048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031048", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UTE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UTE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UTE2" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 109, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VJX6-1", "uniprot_ac": "A0A4X1VJX6", "uniprot_id": "A0A4X1VJX6_PIG", "mass": { "chemical_mass": 88555.0, "monoisotopic_mass": 88555.0 }, "refseq": { "ac": "XP_001926896", "name": "peptidyl-prolyl cis-trans isomerase G", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926896" }, "gene_names": [ { "name": "PPIG", "type": "recommended", "evidence": [ { "id": "A0A4X1VJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6" } ] }, { "name": "PPIG", "type": "synonym", "evidence": [ { "id": "XP_001926896", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926896" } ] } ], "protein_names": [ { "name": "peptidylprolyl isomerase", "type": "recommended", "evidence": [ { "id": "A0A4X1VJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6/entry#names_and_taxonomy" } ] }, { "name": "5.2.1.8", "type": "synonym", "evidence": [ { "id": "A0A4X1VJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6/entry#names_and_taxonomy" } ] }, { "name": "peptidyl-prolyl cis-trans isomerase G", "type": "synonym", "evidence": [ { "id": "XP_001926896", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926896" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJX6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PPIG", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6", "locus": { "chromosome": "15", "start_pos": 75979164, "end_pos": 75940865, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000031123", "url": "https://www.ensembl.org/id/ENSSSCG00000031123" } ] } } ], "crossref": [ { "id": "ENSSSCG00000031123", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000031123", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100155786", "url": "https://www.ncbi.nlm.nih.gov/gene/100155786", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155786", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155786", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NQNQFNR", "url": "https://omabrowser.org/oma/group/NQNQFNR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1VJX6", "url": "https://www.orthodb.org/?gene=A0A4X1VJX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11071:SF292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11071:SF292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001926896", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926896", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A6U3", "url": "https://www.uniprot.org/uniprotkb/A0A287A6U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A6U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A6U3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ALL4", "url": "https://www.uniprot.org/uniprotkb/A0A287ALL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ALL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ALL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VJX6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VJX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VMD8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VMD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VMD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VMD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F7W7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F7W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7W7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKAKKEEKKRHKSSSSSSSSSSESDSSSDSQSSSDSSDSESASEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERESNLPNSQPVSYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEVKENQRSPVRVKEKKITDHRHVSESPNRKTEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDTKHIRHEEKRMRSRSKERDHENVKEKEKADSKAKDQERSRSKEKSKQLESKSNEHDHNKSKDKDRRAQSRSRERDVTKGKHSYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKEYHRYREQEYRRRGRSRSRERRATPGRSRSKDRRRRRRDSRSSEREESQSRNKEKYRNQEGKSSHRKENSEGEKRMYSKNRDHSSSNSNREKKADRDPSPFSKMKQSSQDNELKFSTLKNKEDEKTRSSMEEENQKSKGQENDHTHDKNKKFDHESSPGTDEDKSG", "length": 753, "header": "tr|A0A4X1VJX6-1|A0A4X1VJX6_PIG Isoform 1 of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=PPIG PE=1 SV=1 CANONICAL=A0A4X1VJX6-1" }, "isoforms": [ { "isoform_ac": "A0A287A6U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6/entry#A0A287A6U3-1", "sequence": { "sequence": "MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKAKKEEKKRHKSSSSSSSSSSESDSSSDSQSSSDSSDSESASEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERESNLPNSQPVSYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEVKENQRSPVRVKEKKITDHRHVSESPNRKTEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDTKHIRHEEKRMRSRSKERDHENVKEKEKADSKAKDQERSRSKEKSKQLESKSNEHDHNKSKDKDRRAQSRSRERDVTKGKHSYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKEYHRYREQEYRRRGRSRSRERRATPGRSRSKDRRRRRRDSRSSEREESQSRNKEKYRNQEGKSSHRKENSEGEKRMYSKNRDHSSSNSNREKKADRDPSPFSKMKQSSQDNELKFSTLKNKEDEKTRSSMEEENQKSKGQENDHTHDKNKKFDHESSPGTDEDKSG", "length": 738, "header": "tr|A0A287A6U3-1|A0A4X1VJX6_PIG Computationally mapped isoform of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=PPIG PE=1 SV=1 CANONICAL=A0A4X1VJX6-1" }, "locus": { "chromosome": "15", "start_pos": 75974369, "end_pos": 75945298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063636.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063636.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039665.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039665.2" } ] } }, { "isoform_ac": "A0A287ALL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6/entry#A0A287ALL4-1", "sequence": { "sequence": "MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKAKKEEKKRHKSSSSSSSSSSESDSSSDSQSSSDSSDSESASEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERESNLPNSQPVSYQRRLLVTRSGRKIKGRGPRVVFCFLGLHPQHMEVPRLEVQSEL", "length": 363, "header": "tr|A0A287ALL4-1|A0A4X1VJX6_PIG Computationally mapped isoform of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=PPIG PE=1 SV=2 CANONICAL=A0A4X1VJX6-1" }, "locus": { "chromosome": "15", "start_pos": 75970411, "end_pos": 75945298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041210.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041210.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044915.3", "url": "https://www.ensembl.org/id/ENSSSCP00000044915.3" } ] } }, { "isoform_ac": "A0A4X1VJX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6/entry#A0A4X1VJX6-1", "sequence": { "sequence": "MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKAKKEEKKRHKSSSSSSSSSSESDSSSDSQSSSDSSDSESASEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERESNLPNSQPVSYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEVKENQRSPVRVKEKKITDHRHVSESPNRKTEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDTKHIRHEEKRMRSRSKERDHENVKEKEKADSKAKDQERSRSKEKSKQLESKSNEHDHNKSKDKDRRAQSRSRERDVTKGKHSYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKEYHRYREQEYRRRGRSRSRERRATPGRSRSKDRRRRRRDSRSSEREESQSRNKEKYRNQEGKSSHRKENSEGEKRMYSKNRDHSSSNSNREKKADRDPSPFSKMKQSSQDNELKFSTLKNKEDEKTRSSMEEENQKSKGQENDHTHDKNKKFDHESSPGTDEDKSG", "length": 753, "header": "tr|A0A4X1VJX6-1|A0A4X1VJX6_PIG Isoform 1 of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=PPIG PE=1 SV=1 CANONICAL=A0A4X1VJX6-1" }, "locus": { "chromosome": "15", "start_pos": 75974369, "end_pos": 75945298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066047.3", "url": "https://www.ensembl.org/id/ENSSSCT00000066047.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047092.1", "url": "https://www.ensembl.org/id/ENSSSCP00000047092.1" } ] } }, { "isoform_ac": "A0A4X1VMD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6/entry#A0A4X1VMD8-1", "sequence": { "sequence": "MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFMHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKAKKEEKKRHKSSSSSSSSSSESDSSSDSQSSSDSSDSESASEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERESNLPNSQPVSYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEVKENQRSPVRVKEKKITDHRHVSESPNRKTEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDTKHIRHEEKRMRSRSKERDHENVKEKEKADSKAKDQERSRSKEKSKQLESKSNEHDHNKSKDKDRRAQSRSRERDVTKGKHSYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKEYHRYREQEYRRRGRSRSRERRATPGRSRSKDRRRRRRDSRSSEREESQSRNKEKYRNQEGKSSHRKENSEGEKRMYSKNRDHSSSNSNREKKADRDPSPFSKMKQSSQDNELKFSTLKNKEDEKTRSSMEEENQKSKGQENDHTHDKNKKFDHESSPGTDEDKSG", "length": 743, "header": "tr|A0A4X1VMD8-1|A0A4X1VMD8_PIG Computationally mapped isoform of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=PPIG PE=1 SV=1 CANONICAL=A0A4X1VJX6-1" }, "locus": { "chromosome": "15", "start_pos": 75974369, "end_pos": 75945298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040557.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040557.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059285.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059285.2" } ] } }, { "isoform_ac": "A0A8W4F7W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6/entry#A0A8W4F7W7-1", "sequence": { "sequence": "MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKAKKEEKKRHKSSSSSSSSSSESDSSSDSQSSSDSSDSESASEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERESNLPNSQPVSYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRSELNEVKENQRSPVRVKEKKITDHRHVSESPNRKTEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDTKHIRHEEKRMRSRSKERDHENVKEKEKADSKAKDQERSRSKEKSKQLESKSNEHDHNKSKDKDRRAQSRSRERDVTKGKHSYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKEYHRYREQEYRRRGRSRSRERRATPGRSRSKDRRRRRRDSRSSEREESQSRNKEKYRNQEGKSSHRKENSEGEKRMYSKNRDHSSSNSNREKKADRDPSPFSKMKQSSQDNELKFSTLKNKEDEKTRSSMEEENQKSKGQENDHTHDKNKKFDHESSPGTDEDKSG", "length": 731, "header": "tr|A0A8W4F7W7-1|A0A4X1VJX6_PIG Computationally mapped isoform of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=PPIG PE=1 SV=1 CANONICAL=A0A4X1VJX6-1" }, "locus": { "chromosome": "15", "start_pos": 75974369, "end_pos": 75945298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098687.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098687.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075386.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075386.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A6U3", "url": "https://www.uniprot.org/uniprotkb/A0A287A6U3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155786", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155786", "resource": "KEGG Pathway" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AR02-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "Ppig", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSDSDSSSDSQSSSESSDSESASEEKSRKRKKKHRKNSRKHKKEKKKRKKSKKSPSSESEAENVDAQPQSTVRPEEIPPIPENRFLMRKSPPKADDKERKNRERERERECNPPNSQPASYQRRFLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKEKKITDHRHMSESPNRKVEKEKKAKDHKSESKERDIRRNSEKDDKYNKNKVKKRGKSKSRSKSKERSKSKERDSKHSRHEDKRVRSRSKERDHETTKEKEKPLDPKGKDQERSRSKENSKQVESKSNEHDHSKSKEKDRRAQSRSRERDLTKSKHSYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKEYHRYREQEYRRRGRSRSRDRRTPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRSQESKSSHRKENSEGEKRTYSKSRDHNSSSNNREKKADREQSPVSKTKQSSQDNEVKSSTLKNQEDEKTRSPVEKENQKSKGQENDHVHDKNKKCDHESSPGTDEDKSG", "length": 752 }, "evidence": [ { "id": "A0A4X1VJX6", "url": "https://omabrowser.org/oma/group/A0A4X1VJX6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GU87-1", "protein_name": "peptidylprolyl isomerase", "gene_name": "Ppig", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSDSDSSSDSQSSSDSSDSESASEEKSRKRKKKHRKNSRKHKKEKKKRKKSKKSPSSESEAENLDAQPQSTVRPEEIPPIPENRFLMRKSPPKADDKERKNRERERERECNPPNSQPASYQRRFLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKEKKITDHRHMSESPNRKIEKEKKVKDHKSESKERDIRRNSEKDDKYNKNKVKKRGKSKSRSKSKERSKSKERESKHNKHEDKRMRSRSKDRDHETIKEKEKQVDSKGKDQERSRSKENSKQVESKSDEHDHSKSKEKDRRAQSRSRERDLTKSKHSYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKEYHRYREQEYRRRGRSRSRDRRTPGRSRSKDRRRRRRDSRSSEREESQSRNKEKYRSQESKSSHRKENSEGEKRMYSKNRDHNSSSNNREKKADRDQSPVVLKPKQSSQDNELKSQEDEKTRSPVEKENQKSKGQENDHVHDKNKKCDHESSPGTDEDKSG", "length": 748 }, "evidence": [ { "id": "A0A4X1VJX6", "url": "https://omabrowser.org/oma/group/A0A4X1VJX6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O55035-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "Ppig", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELVPKSKVKKEEKKRHKSSSSSSSSDSDSSSDSQSSSDSSDSESASEEKSRKRKKKHRKNSRKHKKEKKKRKKSKKSPSSESEADNVDAQPQSTVRPEEIPPIPENRFLMRKSPPKADDKERKNRERERERECNPPNSQPASYQRRFLVTRFGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKEKKITDHRHMSESPNRKIEKEKKVKDHKSESKERDIRRNSEKDDKYNKNKVKKRGKSKSRSKSKERSKSKERDSKHSRHEDKRVRSRSKERDHETTKEKEKQLDSKGKDQERSRSKENSKQVESKSNEHDHSKSKEKDRRAQSRSRERDLTKSKHSYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKEYHRYREQEYRRRGRSRSRDRRTPGRSRSKDRRRRRRDSRSSEREESQSRNKEKYRSQDSKSSHRKENSEGEKRMYSKSRDHSSSNNNREKKADIDQSPVSKTKQSSQDNEVKSSTLKNQEDEKTRSPVEKENQKSKGQENDHVHDKNKKCDHESSPGTDEDKSG", "length": 752 }, "evidence": [ { "id": "A0A4X1VJX6", "url": "https://omabrowser.org/oma/group/A0A4X1VJX6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13427-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "PPIG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDKSG", "length": 754 }, "evidence": [ { "id": "A0A4X1VJX6", "url": "https://omabrowser.org/oma/group/A0A4X1VJX6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8RWY7-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase CYP95", "gene_name": "CYP95", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAKKKNPQVFMDVSIDGDPAETMVFELFPEVAPKTSENFRALCTGEKGIGPRSGKPLHYKGSFFHRIMKGSSAQAGDFVNRNGTAGESIYAGKFPDESPKLRHEETGLLSMSIADRDKFGSHFHITFRPNQQLDRNNVVFGKLIQGKEILKKIERVGDEEGKPTVSVKIIRCGEYSGDKKKSDGKKNGKHKKSLRVRRKKRRRHSSSESESSSDSETDSSESDSESDSDLSSPSFLSSSSHERQKKRKRSSKKDKHRRSKQRDKRHEKKRSMRDKRPKRKSRRSPDSLEDSNSGSEASLSDVNVEIGAKKRKHRVSRRTGNSAPAVEKEAESLHQGKRKGPDLLENRGLRSNGISDAASEQISDRQPDIVDDHPSKSRSRSLSPKRTVSKSTSVSPRRSQSKSPSSSPRWNGGRSPAKGSRQVKNLTNSRRESPGSEEKGRHVRRSPTKSVSRSPVRVKKERDISRSPSKSLSRSPLRSPKRVISRSPVRGRIARSPSRSPVRSASRGSLGRGPLRRSSRRSPSRSPVRSSRRSLSRSPIQLSRRSLSRSPTRLSRRSLSRSPIRSPRKSVSRSPVRSSRKSVSRSPVRSSRRRISRSPVRSSRKSVSRSPIRLSRRSISRSPIRLSRRSISRSPVRGRRRISRSPVPARRRSVRPRSPPPDRRRSLSRSASPNGRIRRGRGFSQRFSYARRYRTSPSPDRSPYRFSDRSDRDRFRSRRRFSPSRFRSPLRGRTPPRYRRRSRSVSPGLCYRNRRYSRSPIRSRSPPYRKRRSPSASHSLSPSRSRSRSKSYSKSPIGTGKARSVSRSPSKARSPSKSDSTSSDNSPGGKKGLVAYD", "length": 837 }, "evidence": [ { "id": "A0A4X1VJX6", "url": "https://omabrowser.org/oma/group/A0A4X1VJX6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VAW1-1", "protein_name": "peptidylprolyl isomerase", "gene_name": "Moca-cyp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTVNKRDAGATRPRCFFDISLGGLGMGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKDFMVQAGDFSAGNGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDNIHVVFGQVISGQELVRQLEGLPVDRNSRPLQDAAIANCGELVRQTKAKKEKKHKRRSTATEDSNSEESEAEAKVVRKAKKKKRSRKDTKSQSDSEDNETSRGNGKHDQTPQDDDEDREEGELHPLVTITKIDPNEIPEVSNKFLMRAERSKSLDREERGARGQDRDRGKDQDRDRSRNNFGWSKKQAPPTSRSGRIVKGRGVFRFRTPSRSRSRSTTPPHWKHAQKRTIKLSDLERIEEESKMREEEMKRREHERKRRHEEATKNPKQSFFELSHASTYGGKITPDRFSPEHKAKSKDTADRGKAKEREKAGEKDKARDVTPVKRRKSMDMNALDYEQQTESEVESEDEEQLKVKPPSKQDIRVEPSTSKDRNAKRDERKPTEEKAKPKRSRSRSPRRQSPARRQQRSPARRPGQNYNQNQNQNQNQNQNQNQLNRGNRRNPFADRDRRRRSRSQDNEYRNRYPLSPIRGRGSPSGDRRRQQRSRSQNRRQDSPSQRRQLSPGRKRQDSPSKKRPNSTERKWRDSPERKRDDSHDRKREASPNWKRDDSPARKRKDSANRKREDSQDKKIQDSKRQEDSAGKKREDSPSKKRKDSDKKRQDSPVKRQESPGRKRQDSPERKRRDSPDRRRKDSPARRRQESSGRRRQDSDGRRRRESSGNRRSRSRGRWHSSSRSRSPSTSRSRRRRSRSPLPKLTSALPMSEEREKAAREKMQKRAEAAMLMKEHMRNEIAKEEERRMEKQRQDDLDKERTTRELNELERLKAETLRKLHEEDSVDPDAAASAGSASKTDATSTGAKSKRDSSSENRHREKKRKHKKSKKSSGRSDND", "length": 970 }, "evidence": [ { "id": "A0A4X1VJX6", "url": "https://omabrowser.org/oma/group/A0A4X1VJX6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJX6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJX6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6" } ], "pmid": "" }, { "name": "cyclosporin A binding", "id": "GO:0016018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016018", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJX6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJX6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJX6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJX6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] }, { "id": "R-SSC-9770141", "name": "Formation of the Spliceosomal C* complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-5688092", "R-SSC-5688093", "R-SSC-72073", "R-SSC-9769591", "R-SSC-9769593", "R-SSC-9769594", "R-SSC-9769596", "R-SSC-9769598", "R-SSC-9769599", "R-SSC-9769601" ], "output_participant_list": [ "R-SSC-72060", "R-SSC-8867898", "R-SSC-9770419", "R-SSC-9770425", "R-SSC-9770427", "R-SSC-9770428", "R-SSC-9770430" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9770141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770141" } ] }, { "id": "R-SSC-9770236", "name": "Formation of the Spliceosomal P complex and exon ligation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-9769588", "R-SSC-9769590", "R-SSC-9769602" ], "output_participant_list": [ "R-SSC-6791189", "R-SSC-8849139", "R-SSC-8952113", "R-SSC-9769562" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9770236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770236" } ] }, { "id": "R-SSC-9770847", "name": "Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-5688097", "R-SSC-8869310", "R-SSC-8869311", "R-SSC-9770846" ], "output_participant_list": [ "R-SSC-3900136", "R-SSC-6814858", "R-SSC-8865888", "R-SSC-8865956", "R-SSC-8952110", "R-SSC-9769561", "R-SSC-8867893", "R-SSC-9769592" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9770847", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770847" } ] }, { "id": "R-SSC-9794542", "name": "Formation of the Spliceosomal C complex containing intron lariat", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9794542", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9794542" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-3900136", "participant_name": "DDX5 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000043632", "database": "ENSEMBL", "url": "" }, { "id": "87226", "database": "VGNC", "url": "" }, { "id": "A0A287AHW6", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000032092", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000038465", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-5688092", "participant_name": "DHX8 [nucleoplasm]", "crossref": [ { "id": "F1S1H3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000017378", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000018412", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000018917", "database": "ENSEMBL", "url": "" }, { "id": "87298", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-5688093", "participant_name": "PRPF18 [nucleoplasm]", "crossref": [ { "id": "A0A4X1VY37", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000026354", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000027625", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000024330", "database": "ENSEMBL", "url": "" }, { "id": "NP_001231788.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-5688097", "participant_name": "DHX15 [nucleoplasm]", "crossref": [ { "id": "F1S5A8", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000008756", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000009333", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000009580", "database": "ENSEMBL", "url": "" }, { "id": "87286", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-6791189", "participant_name": "MTREX [nucleoplasm]", "crossref": [ { "id": "F1SLL6", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000017920", "database": "ENSEMBL", "url": "" }, { "id": "90470", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000018417", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000016911", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-6814858", "participant_name": "SRRT [nucleoplasm]", "crossref": [ { "id": "I3LI05", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000023704", "database": "ENSEMBL", "url": "" }, { "id": "93471", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000024767", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000024789", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-72060", "participant_name": "DHX38 [nucleoplasm]", "crossref": [ { "id": "F1S3A8", "database": "UniProt", "url": "" }, { "id": "XP_020949516.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000002966", "database": "ENSEMBL", "url": "" }, { "id": "87294", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000003045", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000002748", "database": "ENSEMBL", "url": "" }, { "id": "XP_020949515.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-72073", "participant_name": "SLU7 [nucleoplasm]", "crossref": [ { "id": "F1RR54", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000017033", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000018045", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000018545", "database": "ENSEMBL", "url": "" }, { "id": "XP_003134141.1", "database": "RefSeq", "url": "" }, { "id": "93214", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-8849139", "participant_name": "DDX39B [nucleoplasm]", "crossref": [ { "id": "XP_005665850.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000001487", "database": "ENSEMBL", "url": "" }, { "id": "NP_001005157.1", "database": "RefSeq", "url": "" }, { "id": "Q29024", "database": "UniProt", "url": "" }, { "id": "ENSSSCT00000001529", "database": "ENSEMBL", "url": "" }, { "id": "XP_005665851.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCG00000001400", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-8865888", "participant_name": "SRRM2 [nucleoplasm]", "crossref": [ { "id": "ENSSSCG00000023304", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000051053", "database": "ENSEMBL", "url": "" }, { "id": "93468", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000041895", "database": "ENSEMBL", "url": "" }, { "id": "A0A287ADD0", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-8865956", "participant_name": "CWC22 [nucleoplasm]", "crossref": [ { "id": "XP_003133562.2", "database": "RefSeq", "url": "" }, { "id": "XP_013839769.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000016961", "database": "ENSEMBL", "url": "" }, { "id": "A0A4X1TWU8", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000016008", "database": "ENSEMBL", "url": "" }, { "id": "XP_005672046.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCT00000017430", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-8867893", "participant_name": "PPWD1 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000017953", "database": "ENSEMBL", "url": "" }, { "id": "NP_001231350.1", "database": "RefSeq", "url": "" }, { "id": "F1SKT8", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000016945", "database": "ENSEMBL", "url": "" }, { "id": "91766", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000018453", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-8867898", "participant_name": "CWC25 [nucleoplasm]", "crossref": [ { "id": "ENSSSCT00000053706", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000021478", "database": "ENSEMBL", "url": "" }, { "id": "87096", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000032040", "database": "ENSEMBL", "url": "" }, { "id": "A0A286ZKR9", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-8869310", "participant_name": "TFIP11 [nucleoplasm]", "crossref": [ { "id": "Q06AK6", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000009962", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000010632", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000010917", "database": "ENSEMBL", "url": "" }, { "id": "XP_020927865.1", "database": "RefSeq", "url": "" }, { "id": "XP_020927864.1", "database": "RefSeq", "url": "" }, { "id": "NP_001070682.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-8869311", "participant_name": "GCFC2 [nucleoplasm]", "crossref": [ { "id": "I3LDF5", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000021287", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000022086", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000031635", "database": "ENSEMBL", "url": "" }, { "id": "XP_020942970.1", "database": "RefSeq", "url": "" }, { "id": "88382", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-8952110", "participant_name": "PPIL3 [nucleoplasm]", "crossref": [ { "id": "XP_013839835.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCT00000017525", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000016096", "database": "ENSEMBL", "url": "" }, { "id": "XP_001926016.1", "database": "RefSeq", "url": "" }, { "id": "XP_005672124.1", "database": "RefSeq", "url": "" }, { "id": "103073", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000017053", "database": "ENSEMBL", "url": "" }, { "id": "XP_001925960.1", "database": "RefSeq", "url": "" }, { "id": "F2Z5T7", "database": "UniProt", "url": "" }, { "id": "XP_005672126.1", "database": "RefSeq", "url": "" }, { "id": "XP_005672125.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-8952113", "participant_name": "PPIL4 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000023314", "database": "ENSEMBL", "url": "" }, { "id": "91699", "database": "VGNC", "url": "" }, { "id": "I3LGX0", "database": "UniProt", "url": "" }, { "id": "ENSSSCT00000024741", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000028867", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769561", "participant_name": "CCDC12 [nucleoplasm]", "crossref": [ { "id": "A0A8W4FDT6", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000077421", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000093297", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000011329", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769562", "participant_name": "PPIL2 [nucleoplasm]", "crossref": [ { "id": "ENSSSCG00000010083", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000056926", "database": "ENSEMBL", "url": "" }, { "id": "91698", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000040807", "database": "ENSEMBL", "url": "" }, { "id": "A0A287AAH2", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-9769588", "participant_name": "C1H9orf78 [nucleoplasm]", "crossref": [ { "id": "F1RQE0", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000030426", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000022510", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000024953", "database": "ENSEMBL", "url": "" }, { "id": "85975", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769590", "participant_name": "LENG1 [nucleoplasm]", "crossref": [ { "id": "F1RNH2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000003265", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000003541", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000003626", "database": "ENSEMBL", "url": "" }, { "id": "XP_003127463.2", "database": "RefSeq", "url": "" }, { "id": "89680", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769591", "participant_name": "CACTIN [nucleoplasm]", "crossref": [ { "id": "A0A287BJU2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000032085", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000056347", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000037250", "database": "ENSEMBL", "url": "" }, { "id": "86131", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769592", "participant_name": "PPIG [nucleoplasm]", "crossref": [ { "id": "XP_005671972.1", "database": "RefSeq", "url": "" }, { "id": "XP_020931930.1", "database": "RefSeq", "url": "" }, { "id": "XP_005671971.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000047092", "database": "ENSEMBL", "url": "" }, { "id": "XP_020931929.1", "database": "RefSeq", "url": "" }, { "id": "A0A4X1VJX6", "database": "UniProt", "url": "" }, { "id": "XP_020931927.1", "database": "RefSeq", "url": "" }, { "id": "XP_005671973.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCG00000031123", "database": "ENSEMBL", "url": "" }, { "id": "XP_001926896.1", "database": "RefSeq", "url": "" }, { "id": "XP_020931928.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCT00000066047", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769593", "participant_name": "SDE2 [nucleoplasm]", "crossref": [ { "id": "A0A8W4FFC9", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000010858", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000078134", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000092221", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769594", "participant_name": "PRKRIP1 [nucleoplasm]", "crossref": [ { "id": "A0A5G2QNT3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000042324", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000065720", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000069793", "database": "ENSEMBL", "url": "" }, { "id": "XP_005661993.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9769596", "participant_name": "STEEP1 [nucleoplasm]", "crossref": [ { "id": "F2Z566", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000012622", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000013420", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000013801", "database": "ENSEMBL", "url": "" }, { "id": "87113", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769598", "participant_name": "FAM32A [nucleoplasm]", "crossref": [ { "id": "A0A4X1UYF2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000013855", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000014729", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000015134", "database": "ENSEMBL", "url": "" }, { "id": "NP_001230816.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9769599", "participant_name": "FAM50A [nucleoplasm]", "crossref": [ { "id": "A0A5G2QKU3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000025303", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000064609", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000089389", "database": "ENSEMBL", "url": "" }, { "id": "87972", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769601", "participant_name": "DDX41 [nucleoplasm]", "crossref": [ { "id": "A0A287AWY6", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000032642", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000048662", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000059325", "database": "ENSEMBL", "url": "" }, { "id": "87221", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769602", "participant_name": "NKAP [nucleoplasm]", "crossref": [ { "id": "A0A5G2RJX5", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000012613", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000072270", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000085170", "database": "ENSEMBL", "url": "" }, { "id": "90756", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9770419", "participant_name": "GPATCH1 [nucleoplasm]", "crossref": [ { "id": "ENSSSCP00000003085", "database": "ENSEMBL", "url": "" }, { "id": "XP_020949947.1", "database": "RefSeq", "url": "" }, { "id": "F1RNW7", "database": "UniProt", "url": "" }, { "id": "88573", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000003166", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000002865", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9770425", "participant_name": "WDR70 [nucleoplasm]", "crossref": [ { "id": "ENSSSCT00000018344", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000016846", "database": "ENSEMBL", "url": "" }, { "id": "94937", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000017848", "database": "ENSEMBL", "url": "" }, { "id": "F1SN94", "database": "UniProt", "url": "" }, { "id": "XP_020932620.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9770427", "participant_name": "DHX35 [nucleoplasm]", "crossref": [ { "id": "95678", "database": "VGNC", "url": "" }, { "id": "ENSSSCG00000007352", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000063112", "database": "ENSEMBL", "url": "" }, { "id": "A0A287B5Q0", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000051779", "database": "ENSEMBL", "url": "" }, { "id": "XP_001929057.3", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9770428", "participant_name": "NSRP1 [nucleoplasm]", "crossref": [ { "id": "A0A8D1TUT0", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000018853", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000019367", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000017795", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9770430", "participant_name": "YJU2 [nucleoplasm]", "crossref": [ { "id": "ENSSSCG00000013499", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000072636", "database": "ENSEMBL", "url": "" }, { "id": "95033", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000068755", "database": "ENSEMBL", "url": "" }, { "id": "A0A5G2QX80", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-9770846", "participant_name": "CWF19L2 [nucleoplasm]", "crossref": [ { "id": "A0A5K1V0N0", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000028201", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000028057", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000026318", "database": "ENSEMBL", "url": "" }, { "id": "96726", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1VJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJX6" }, { "id": "PS50072", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50072" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPIase cyclophilin-type", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 176, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 532, "end_pos": 534 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1V637-1", "uniprot_ac": "A0A4X1V637", "uniprot_id": "A0A4X1V637_PIG", "mass": { "chemical_mass": 37073.0, "monoisotopic_mass": 37073.0 }, "refseq": { "ac": "XP_005657108", "name": "nuclear distribution protein nudE-like 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657108" }, "gene_names": [ { "name": "NDEL1", "type": "recommended", "evidence": [ { "id": "A0A4X1V637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ] }, { "name": "NDEL1", "type": "synonym", "evidence": [ { "id": "XP_005657108", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657108" } ] } ], "protein_names": [ { "name": "Nuclear distribution protein nudE-like 1", "type": "recommended", "evidence": [ { "id": "A0A4X1V637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637/entry#names_and_taxonomy" } ] }, { "name": "nuclear distribution protein nudE-like 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005657108", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657108" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NDEL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637", "locus": { "chromosome": "12", "start_pos": 53640457, "end_pos": 53557175, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017986", "url": "https://www.ensembl.org/id/ENSSSCG00000017986" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017986", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017986", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100511592", "url": "https://www.ncbi.nlm.nih.gov/gene/100511592", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1V637", "url": "https://www.orthodb.org/?gene=A0A4X1V637", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8D1JIE2", "url": "https://www.orthodb.org/?gene=A0A8D1JIE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10921", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10921", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10921:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10921:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68877", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005657108", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657108", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V637-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VAJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VAJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VAJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VAJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VS15", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VS15-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VS15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1JIE2", "url": "https://www.uniprot.org/uniprotkb/A0A8D1JIE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1JIE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1JIE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENSFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVMNSNGTKFSRSGHTSFFDKGQEKVIFPTLFMGQ", "length": 328, "header": "tr|A0A4X1V637-1|A0A4X1V637_PIG Isoform 1 of Nuclear distribution protein nudE-like 1 OS=Sus scrofa OX=9823 GN=NDEL1 PE=3 SV=1 CANONICAL=A0A4X1V637-1" }, "isoforms": [ { "isoform_ac": "A0A4X1V637-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637/entry#A0A4X1V637-1", "sequence": { "sequence": "MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENSFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVMNSNGTKFSRSGHTSFFDKGQEKVIFPTLFMGQ", "length": 328, "header": "tr|A0A4X1V637-1|A0A4X1V637_PIG Isoform 1 of Nuclear distribution protein nudE-like 1 OS=Sus scrofa OX=9823 GN=NDEL1 PE=3 SV=1 CANONICAL=A0A4X1V637-1" }, "locus": { "chromosome": "12", "start_pos": 53639233, "end_pos": 53612437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027254.4", "url": "https://www.ensembl.org/id/ENSSSCT00000027254.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022882.2", "url": "https://www.ensembl.org/id/ENSSSCP00000022882.2" } ] } }, { "isoform_ac": "A0A4X1VAJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637/entry#A0A4X1VAJ7-1", "sequence": { "sequence": "MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENSFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGGSKRL", "length": 269, "header": "tr|A0A4X1VAJ7-1|A0A4X1VAJ7_PIG Computationally mapped isoform of Nuclear distribution protein nudE-like 1 OS=Sus scrofa OX=9823 GN=NDEL1 PE=3 SV=1 CANONICAL=A0A4X1V637-1" }, "locus": { "chromosome": "12", "start_pos": 53639243, "end_pos": 53612437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019572.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019572.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019054.4", "url": "https://www.ensembl.org/id/ENSSSCP00000019054.4" } ] } }, { "isoform_ac": "A0A5G2QHR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637/entry#A0A5G2QHR9-1", "sequence": { "sequence": "MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAACRGGCWAPSPRTLRDLNTGSFLFSP", "length": 84, "header": "tr|A0A5G2QHR9-1|A0A4X1V637_PIG Computationally mapped isoform of Nuclear distribution protein nudE-like 1 OS=Sus scrofa OX=9823 GN=NDEL1 PE=3 SV=1 CANONICAL=A0A4X1V637-1" }, "locus": { "chromosome": "12", "start_pos": 53639531, "end_pos": 53612437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105936.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105936.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078055.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078055.1" } ] } }, { "isoform_ac": "A0A5K1VS15-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637/entry#A0A5K1VS15-1", "sequence": { "sequence": "MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENSFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVMNSNGTKFSRSGHTSFFDKGAVNGFDPAPPPPGLGYGRRFRGLGARRAVPPPSPPPPRASDSG", "length": 358, "header": "tr|A0A5K1VS15-1|A0A4X1V637_PIG Computationally mapped isoform of Nuclear distribution protein nudE-like 1 OS=Sus scrofa OX=9823 GN=NDEL1 PE=3 SV=2 CANONICAL=A0A4X1V637-1" }, "locus": { "chromosome": "12", "start_pos": 53640019, "end_pos": 53612437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028487.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028487.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020110.4", "url": "https://www.ensembl.org/id/ENSSSCP00000020110.4" } ] } }, { "isoform_ac": "A0A8D1JIE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637/entry#A0A8D1JIE2-1", "sequence": { "sequence": "MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENSFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVMNSNGTKFSRSGHTSFFDKGAVNGFDPAPPPPGLGSSRPSSAPGMLPLSV", "length": 345, "header": "tr|A0A8D1JIE2-1|A0A4X1V637_PIG Computationally mapped isoform of Nuclear distribution protein nudE-like 1 OS=Sus scrofa OX=9823 GN=NDEL1 PE=3 SV=1 CANONICAL=A0A4X1V637-1" }, "locus": { "chromosome": "12", "start_pos": 53639319, "end_pos": 53612437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049254.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049254.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039451.3", "url": "https://www.ensembl.org/id/ENSSSCP00000039451.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QHR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHR9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-SSC-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-SSC-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-SSC-68877", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "resource": "Reactome", "description": "Mitotic Prometaphase" }, { "id": "R-SSC-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 15, "go_terms": [ { "name": "cerebral cortex radially oriented cell migration", "id": "GO:0021799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021799", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "regulation of neuron projection development", "id": "GO:0010975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010975", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "regulation of intracellular protein transport", "id": "GO:0033157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033157", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "vesicle transport along microtubule", "id": "GO:0047496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047496", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "mitotic centrosome separation", "id": "GO:0007100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007100", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "positive regulation of ruffle assembly", "id": "GO:1900029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900029", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "chromosome localization", "id": "GO:0050000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050000", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "axon hillock", "id": "GO:0043203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043203", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "neurofilament cytoskeleton", "id": "GO:0060053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060053", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V637", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1V637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V637" }, { "id": "PF04880", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04880" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NUDE", "eco_id": "ECO_0000259", "start_pos": 135, "end_pos": 307, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 299, "end_pos": 301 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U3H6-1", "uniprot_ac": "A0A4X1U3H6", "uniprot_id": "A0A4X1U3H6_PIG", "mass": { "chemical_mass": 33543.0, "monoisotopic_mass": 33543.0 }, "refseq": { "ac": "XP_020934447", "name": "uridine phosphorylase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934447" }, "gene_names": [ { "name": "UPP1", "type": "recommended", "evidence": [ { "id": "A0A4X1U3H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6" } ] }, { "name": "UPP1", "type": "synonym", "evidence": [ { "id": "XP_020934447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934447" } ] } ], "protein_names": [ { "name": "Uridine phosphorylase", "type": "recommended", "evidence": [ { "id": "A0A4X1U3H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6/entry#names_and_taxonomy" } ] }, { "name": "2.4.2.3", "type": "synonym", "evidence": [ { "id": "A0A4X1U3H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6/entry#names_and_taxonomy" } ] }, { "name": "uridine phosphorylase 1", "type": "synonym", "evidence": [ { "id": "XP_020934447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934447" } ] } ], "function": [ { "annotation": "Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate which can then be utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows broad substrate specificity and can also accept deoxyuridine and other analogous compounds.", "evidence": [ { "database": "UniProtKB", "id": "I3LSZ5", "url": "https://www.uniprot.org/uniprotkb/I3LSZ5#function" }, { "database": "UniProtKB", "id": "RU361131", "url": "https://www.uniprot.org/uniprotkb/RU361131#function" }, { "database": "UniProtKB", "id": "A0A287A0H1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0H1#function" }, { "database": "UniProtKB", "id": "A0A4X1U3H6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3H6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UPP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6", "locus": { "chromosome": "18", "start_pos": 48418385, "end_pos": 48440736, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000030388", "url": "https://www.ensembl.org/id/ENSSSCG00000030388" } ] } } ], "crossref": [ { "id": "ENSSSCG00000030388", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000030388", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17763", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17763", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100625277", "url": "https://www.ncbi.nlm.nih.gov/gene/100625277", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100625277", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625277", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HPNICAG", "url": "https://omabrowser.org/oma/group/HPNICAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U3H6", "url": "https://www.orthodb.org/?gene=A0A4X1U3H6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43691", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43691", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43691:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43691:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01048", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01048", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-73614", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73614", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73621", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73621", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020934447", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934447", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24388", "url": "https://www.rhea-db.org/rhea/24388", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A0H1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A0H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0H1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U3H6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U3H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LSZ5", "url": "https://www.uniprot.org/uniprotkb/I3LSZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LSZ5-1", "url": "https://www.uniprot.org/uniprotkb/I3LSZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASAGAETKKLGNDNDFVRLSNPHLATMKEDVLYHFSLSTGTHDFPAMFGDVKFVCVGGSPSRMKAFIQYVAVELGLDVPGADYPNICVGTDRYAMFKVGPVLSVSHGMGIPSIAIMLHELIKLLYHARCSGVTIIRIGTSGGIGLEPGSVVITRQAVDPCFKPEFEQVVLGKRVVRSTHLDEPLMEELAQCSADLGEFPTVVGNTMCTLDFYEGQGRLDGALCSYAEKDKREYLNAAHAAGVRNIEMESSVFAAMCNACGLRAAVVCVTLLNRLEGDQISSPHEVLVEYQQRPQRLVGHFIKKRLSAA", "length": 309, "header": "tr|A0A4X1U3H6-1|A0A4X1U3H6_PIG Isoform 1 of Uridine phosphorylase OS=Sus scrofa OX=9823 GN=UPP1 PE=1 SV=1 CANONICAL=A0A4X1U3H6-1" }, "isoforms": [ { "isoform_ac": "A0A287A0H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6/entry#A0A287A0H1-1", "sequence": { "sequence": "MSNRVVSPVVRRRPLGRRKRREEVRAGRGRGRGRGRWEGGAGGEGRGRAAGDPPAGLARVYPPGLRSLAGTSGTCGGTALARPQVASLWPEAHTCGGPCAVKGLRPALCFREASCRDFVRLSNPHLATMKEDVLYHFSLSTGTHDFPAMFGDVKFVCVGGSPSRMKAFIQYVAVELGLDVPGADYPNICVGTDRYAMFKVGPVLSVSHGMGIPSIAIMLHELIKLLYHARCSGVTIIRIGTSGGIGLEPGSVVITRQAVDPCFKPEFEQVVLGKRVVRSTHLDEPLMEELAQCSADLGEFPTVVGNTMCTLDFYEGQGRLDGALCSYAEKDKREYLNAAHAAGVRNIEMESSVFAAMCNACGLRAAVVCVTLLNRLEGDQISSPHEVLVEYQQRPQRLVGHFIKKRLSAA", "length": 410, "header": "tr|A0A287A0H1-1|A0A4X1U3H6_PIG Computationally mapped isoform of Uridine phosphorylase OS=Sus scrofa OX=9823 GN=UPP1 PE=1 SV=1 CANONICAL=A0A4X1U3H6-1" }, "locus": { "chromosome": "18", "start_pos": 48440460, "end_pos": 48418450, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052968.2", "url": "https://www.ensembl.org/id/ENSSSCT00000052968.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037244.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037244.2" } ] } }, { "isoform_ac": "A0A4X1U3H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6/entry#A0A4X1U3H6-1", "sequence": { "sequence": "MASAGAETKKLGNDNDFVRLSNPHLATMKEDVLYHFSLSTGTHDFPAMFGDVKFVCVGGSPSRMKAFIQYVAVELGLDVPGADYPNICVGTDRYAMFKVGPVLSVSHGMGIPSIAIMLHELIKLLYHARCSGVTIIRIGTSGGIGLEPGSVVITRQAVDPCFKPEFEQVVLGKRVVRSTHLDEPLMEELAQCSADLGEFPTVVGNTMCTLDFYEGQGRLDGALCSYAEKDKREYLNAAHAAGVRNIEMESSVFAAMCNACGLRAAVVCVTLLNRLEGDQISSPHEVLVEYQQRPQRLVGHFIKKRLSAA", "length": 309, "header": "tr|A0A4X1U3H6-1|A0A4X1U3H6_PIG Isoform 1 of Uridine phosphorylase OS=Sus scrofa OX=9823 GN=UPP1 PE=1 SV=1 CANONICAL=A0A4X1U3H6-1" }, "locus": { "chromosome": "18", "start_pos": 48430236, "end_pos": 48418450, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065553.2", "url": "https://www.ensembl.org/id/ENSSSCT00000065553.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048025.1", "url": "https://www.ensembl.org/id/ENSSSCP00000048025.1" } ] } }, { "isoform_ac": "I3LSZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6/entry#I3LSZ5-1", "sequence": { "sequence": "TLSTFLFWDSDFVRLSNPHLATMKEDVLYHFSLSTGTHDFPAMFGDVKFVCVGGSPSRMKAFIQYVAVELGLDVPGADYPNICVGTDRYAMFKVGPVLSVSHGMGIPSIAIMLHELIKLLYHARCSGVTIIRIGTSGGIGLEPGSVVITRQAVDPCFKPEFEQVVLGKRVVRSTHLDEPLMEELAQCSADLGEFPTVVGNTMCTLDFYEGQGRLDGALCSYAEKDKREYLNAAHAAGVRNIEMESSVFAAMCNACGLRAAVVCVTLLNRLEGDQISSPHEVLVEYQQRPQRLVGHFIKKRLSAA", "length": 304, "header": "tr|I3LSZ5-1|A0A4X1U3H6_PIG Computationally mapped isoform of Uridine phosphorylase OS=Sus scrofa OX=9823 GN=UPP1 PE=1 SV=3 CANONICAL=A0A4X1U3H6-1" }, "locus": { "chromosome": "18", "start_pos": 48426629, "end_pos": 48418450, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024494.3", "url": "https://www.ensembl.org/id/ENSSSCT00000024494.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027238.3", "url": "https://www.ensembl.org/id/ENSSSCP00000027238.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0H1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0H1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100625277", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625277", "resource": "KEGG Pathway" }, { "id": "R-SSC-73614", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73614", "resource": "Reactome", "description": "Pyrimidine salvage" }, { "id": "R-SSC-73621", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73621", "resource": "Reactome", "description": "Pyrimidine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LQS1-1", "protein_name": "Uridine phosphorylase", "gene_name": "Upp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAATGTEAKDLENHHNDCFVQVSNPNIATMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSPSRMSTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKVGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVDECFKPEFEQIVLGKRVVRSTNLDVKLVQELMQCSSDLNEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLQAAHAAGVRNIEMESSLFATMCSACGLRAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGKA", "length": 311 }, "evidence": [ { "id": "A0A4X1U3H6", "url": "https://omabrowser.org/oma/group/A0A4X1U3H6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0X899-1", "protein_name": "Uridine phosphorylase", "gene_name": "UPP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVMGQTGFSNIVDIEKRFKIHQKIVSSPKVQAYMAPGVSNEKKREDEQSSRENSIHLCNPHLEKMKEDILYHFALGTGTHDFPALFGDVKFVCVGGSPSRMKAFIAYIAEELGLGSSGGDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYHAKCSNITIIRIGTSGGIGLEPGSVVITRQSVDATFKPQFEQVVLGKTIIRSTNLDEELAKELLQCSKEINQFNTVIGNTMCTLDFYEGQGRLDGAICLYNEEEKLQYLKEAYDSGVRNIEMESSVFAAMCNLSGVRAAVVCVTLLNRLEGDQISSSHDILVEYQQRPQKLVGYFIKKSLGKV", "length": 346 }, "evidence": [ { "id": "A0A4X1U3H6", "url": "https://omabrowser.org/oma/group/A0A4X1U3H6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N0Y0-1", "protein_name": "Uridine phosphorylase", "gene_name": "UPP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSHFLPPSRALLGPGESQSEPGPERPRGPPLACGAHSHPQPNASSTPVTLALAPDNPPAPRLHSGWVPADTLAPAGAVTSGGHLCPLSLCCQEGKKPQGGVVGGTSGLMSKRLVSGHSPSPAAQQETRRGWGGGAGMGGAAGRRAGTPGRPDSTSSPVPPGTGRAVSARGASVAGVQFSGITLPGPASAEGMASTAAETEKPEDHNDLVQLCNPHIAAMKEDILYHFSLSTSTHDFPAMFGDVKFVCVGGSPSRMKAFIKYVAMELGFAHPGADYPNICEGTDRYAMFKVGPVLSVSHGMGVPSIAIMLHELIKLLYHARCSGVTLIRIGTSGGIGLEPGSVVITRQAVDPCFKPEFEQIVLGKREVRNTDLDEQLVQELARCSAELGEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQEYLRAAYAAGIRNIEMEASVFAAMCNACGLRAAVVCVTLLNRLEGDQISSPHEVLAEYQQRPQRLVGQFIKKRLMQA", "length": 500 }, "evidence": [ { "id": "A0A4X1U3H6", "url": "https://omabrowser.org/oma/group/A0A4X1U3H6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7F0D5-1", "protein_name": "Uridine phosphorylase", "gene_name": "Upp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAATGTEAKDLENHHNSDCLVQLSNPNIATMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMSAFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVDECFKPEFEQIVLGKRVTRNTSLDAQLVQELMQCSSDLNEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHNVLVEYQQRPQRLVGHFIKKRLGRA", "length": 312 }, "evidence": [ { "id": "A0A4X1U3H6", "url": "https://omabrowser.org/oma/group/A0A4X1U3H6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P52624-1", "protein_name": "Uridine phosphorylase 1", "gene_name": "Upp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA", "length": 311 }, "evidence": [ { "id": "A0A4X1U3H6", "url": "https://omabrowser.org/oma/group/A0A4X1U3H6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q16831-1", "protein_name": "Uridine phosphorylase 1", "gene_name": "UPP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKLSKA", "length": 310 }, "evidence": [ { "id": "A0A4X1U3H6", "url": "https://omabrowser.org/oma/group/A0A4X1U3H6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "uridine phosphorylase activity", "id": "GO:0004850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004850", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3H6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3H6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "uridine catabolic process", "id": "GO:0006218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006218", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3H6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6" } ], "pmid": "" }, { "name": "UMP salvage", "id": "GO:0044206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044206", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3H6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6" } ], "pmid": "" }, { "name": "nucleotide catabolic process", "id": "GO:0009166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009166", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3H6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6" } ], "pmid": "" }, { "name": "nucleoside catabolic process", "id": "GO:0009164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009164", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3H6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3H6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3H6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3H6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24388", "name": "", "equation": "uridine + phosphate = alpha-D-ribose 1-phosphate + uracil", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "24388", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24388" } ] }, { "id": "R-SSC-74372", "name": "uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-74372", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-74372" } ] }, { "id": "R-SSC-74376", "name": "(deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-74376", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-74376" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U3H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3H6" }, { "id": "PF01048", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01048" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleoside phosphorylase", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 303, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1V9D1-1", "uniprot_ac": "A0A4X1V9D1", "uniprot_id": "A0A4X1V9D1_PIG", "mass": { "chemical_mass": 77623.0, "monoisotopic_mass": 77623.0 }, "refseq": { "ac": "XP_020958248", "name": "SRSF protein kinase 2 isoform X13", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958248" }, "gene_names": [ { "name": "SRPK2", "type": "recommended", "evidence": [ { "id": "A0A4X1V9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ] }, { "name": "SRPK2", "type": "synonym", "evidence": [ { "id": "XP_020958248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958248" } ] } ], "protein_names": [ { "name": "SRSF protein kinase 2", "type": "recommended", "evidence": [ { "id": "A0A4X1V9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A4X1V9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1/entry#names_and_taxonomy" } ] }, { "name": "SFRS protein kinase 2", "type": "synonym", "evidence": [ { "id": "A0A4X1V9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1/entry#names_and_taxonomy" } ] }, { "name": "SRSF protein kinase 2 isoform X13", "type": "synonym", "evidence": [ { "id": "XP_020958248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958248" } ] }, { "name": "Serine/arginine-rich protein-specific kinase 2", "type": "synonym", "evidence": [ { "id": "A0A4X1V9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SRPK2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1", "locus": { "chromosome": "9", "start_pos": 105006987, "end_pos": 105264731, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026110", "url": "https://www.ensembl.org/id/ENSSSCG00000026110" } ] } } ], "crossref": [ { "id": "A0A4X1V9D1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1V9D1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026110", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026110", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100627848", "url": "https://www.ncbi.nlm.nih.gov/gene/100627848", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47634", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47634", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47634:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47634:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020958248", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958248", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A5X3", "url": "https://www.uniprot.org/uniprotkb/A0A287A5X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A5X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A5X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AP93", "url": "https://www.uniprot.org/uniprotkb/A0A287AP93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AP93-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AP93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V8L2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V8L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8L2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V9D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1C3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8D1C3Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1C3Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1C3Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L729", "url": "https://www.uniprot.org/uniprotkb/I3L729", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L729-1", "url": "https://www.uniprot.org/uniprotkb/I3L729-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPNDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENVTSSVPSNEQDDEYHPEVKLKTAEIEEAAEGETSNNNGEAEDQEEKEDTEKENTEKDEDDVEQELANIDPTWIESPKTNGHIENGPFLLEQQLDDEDEEEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGPLEPVACGSALSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKTKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS", "length": 686, "header": "tr|A0A4X1V9D1-1|A0A4X1V9D1_PIG Isoform 1 of SRSF protein kinase 2 OS=Sus scrofa OX=9823 GN=SRPK2 PE=1 SV=1 CANONICAL=A0A4X1V9D1-1" }, "isoforms": [ { "isoform_ac": "A0A287A5X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1/entry#A0A287A5X3-1", "sequence": { "sequence": "MGMQGCRGAKGEKRPREERWCETHGGAGPGKAHGEAGSASGRVLAIQARKRRPKREKHPKKPEPQQKAPLVPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPNDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENVTSSVPSNEQDDEYHPEVKLKTAEIEEAAEGETSNNNGEAEDQEEKEDTEKENTEKDEDDVEQELANIDPTWIESPKTNGHIENGPFLLEQQLDDEDEEEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGPLEPVACGSALSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKTKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIALIIELLGKVPRKYAMLGKYSKEFFTRKGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS", "length": 734, "header": "tr|A0A287A5X3-1|A0A4X1V9D1_PIG Computationally mapped isoform of SRSF protein kinase 2 OS=Sus scrofa OX=9823 GN=SRPK2 PE=1 SV=2 CANONICAL=A0A4X1V9D1-1" }, "locus": { "chromosome": "9", "start_pos": 105264674, "end_pos": 105011091, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045963.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045963.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039267.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039267.2" } ] } }, { "isoform_ac": "A0A287AP93-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1/entry#A0A287AP93-1", "sequence": { "sequence": "MQHTPPPLLVICVVLTLKDLRLIYCGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPNDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENVTSSVPSNEQDDEYHPEVKLKTAEIEEAAEGETSNNNGEAEDQEEKEDTEKENTEKDEDDVEQELANIDPTWIESPKTNGHIENGPFLLEQQLDDEDEEEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGPLEPVACGSALSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKTKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRDHIALIIELLGKVPRKYAMLGKYSKEFFTRKGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS", "length": 678, "header": "tr|A0A287AP93-1|A0A4X1V9D1_PIG Computationally mapped isoform of SRSF protein kinase 2 OS=Sus scrofa OX=9823 GN=SRPK2 PE=1 SV=3 CANONICAL=A0A4X1V9D1-1" }, "locus": { "chromosome": "9", "start_pos": 105062317, "end_pos": 105011091, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044705.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044705.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045719.3", "url": "https://www.ensembl.org/id/ENSSSCP00000045719.3" } ] } }, { "isoform_ac": "A0A4X1V8L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1/entry#A0A4X1V8L2-1", "sequence": { "sequence": "MEQSLHAVMVHACRPEPQQKAPLVPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPNDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENVTSSVPSNEQDDEYHPEVKLKTAEIEEAAEGETSNNNGEAEDQEEKEDTEKENTEKDEDDVEQELANIDPTWIESPKTNGHIENGPFLLEQQLDDEDEEEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGPLEPVACGSALSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKTKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS", "length": 687, "header": "tr|A0A4X1V8L2-1|A0A4X1V8L2_PIG Computationally mapped isoform of SRSF protein kinase 2 OS=Sus scrofa OX=9823 GN=SRPK2 PE=1 SV=1 CANONICAL=A0A4X1V9D1-1" }, "locus": { "chromosome": "9", "start_pos": 105157922, "end_pos": 105011091, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061105.1", "url": "https://www.ensembl.org/id/ENSSSCT00000061105.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051829.1", "url": "https://www.ensembl.org/id/ENSSSCP00000051829.1" } ] } }, { "isoform_ac": "A0A4X1V9D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1/entry#A0A4X1V9D1-1", "sequence": { "sequence": "MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPNDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENVTSSVPSNEQDDEYHPEVKLKTAEIEEAAEGETSNNNGEAEDQEEKEDTEKENTEKDEDDVEQELANIDPTWIESPKTNGHIENGPFLLEQQLDDEDEEEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGPLEPVACGSALSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKTKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS", "length": 686, "header": "tr|A0A4X1V9D1-1|A0A4X1V9D1_PIG Isoform 1 of SRSF protein kinase 2 OS=Sus scrofa OX=9823 GN=SRPK2 PE=1 SV=1 CANONICAL=A0A4X1V9D1-1" }, "locus": { "chromosome": "9", "start_pos": 105158514, "end_pos": 105011091, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038637.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038637.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052504.3", "url": "https://www.ensembl.org/id/ENSSSCP00000052504.3" } ] } }, { "isoform_ac": "A0A8D1C3Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1/entry#A0A8D1C3Z8-1", "sequence": { "sequence": "WEPPYAAGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPNDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENVTSSVPSNEQDDEYHPEVKLKTAEIEEAAEGETSNNNGEAEDQEEKEDTEKENTEKDEDDVEQELANIDPTWIESPKTNGHIENGPFLLEQQLDDEDEEEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGPLEPVACGSALSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKTKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRDHIALIIELLGKVPRKYAMLGKYSKEFFTRKGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS", "length": 661, "header": "tr|A0A8D1C3Z8-1|A0A4X1V9D1_PIG Computationally mapped isoform of SRSF protein kinase 2 OS=Sus scrofa OX=9823 GN=SRPK2 PE=1 SV=1 CANONICAL=A0A4X1V9D1-1" }, "locus": { "chromosome": "9", "start_pos": 105062574, "end_pos": 105011091, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047918.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047918.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044573.2", "url": "https://www.ensembl.org/id/ENSSSCP00000044573.2" } ] } }, { "isoform_ac": "I3L729-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1/entry#I3L729-1", "sequence": { "sequence": "MGASFSTSLCFELLFHLRPEPQQKAPLVPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPNDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIIEENVTSSVPSNEQDDEYHPEVKLKTAEIEEAAEGETSNNNGEAEDQEEKEDTEKENTEKDEDDVEQELANIDPTWIESPKTNGHIENGPFLLEQQLDDEDEEEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGRHKIPESQFPEFSTSLFSGPLEPVACGSALSEGSPLTEQEESSPSHDRSRTVSASSTGDLPKTKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRDHIALIIELLGKVPRKYAMLGKYSKEFFTRKGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS", "length": 722, "header": "tr|I3L729-1|I3L729_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SRPK2 PE=1 SV=3 CANONICAL=A0A4X1V9D1-1" }, "locus": { "chromosome": "9", "start_pos": 105113336, "end_pos": 105011091, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032237.4", "url": "https://www.ensembl.org/id/ENSSSCT00000032237.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019833.3", "url": "https://www.ensembl.org/id/ENSSSCP00000019833.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A5X3", "url": "https://www.uniprot.org/uniprotkb/A0A287A5X3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "negative regulation of viral genome replication", "id": "GO:0045071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045071", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "positive regulation of viral genome replication", "id": "GO:0045070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045070", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "regulation of mRNA processing", "id": "GO:0050684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050684", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" }, { "name": "R-loop processing", "id": "GO:0062176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062176", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V9D1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1V9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V9D1" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 684, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 39 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 303, "end_pos": 305 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UE49-1", "uniprot_ac": "A0A4X1UE49", "uniprot_id": "A0A4X1UE49_PIG", "mass": { "chemical_mass": 47715.0, "monoisotopic_mass": 47715.0 }, "refseq": { "ac": "XP_020958022", "name": "cyclin-dependent kinase 14 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958022" }, "gene_names": [ { "name": "CDK14", "type": "recommended", "evidence": [ { "id": "A0A4X1UE49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ] }, { "name": "CDK14", "type": "synonym", "evidence": [ { "id": "XP_020958022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958022" } ] } ], "protein_names": [ { "name": "Cyclin-dependent kinase 14", "type": "recommended", "evidence": [ { "id": "A0A4X1UE49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.22", "type": "synonym", "evidence": [ { "id": "A0A4X1UE49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49/entry#names_and_taxonomy" } ] }, { "name": "Cell division protein kinase 14", "type": "synonym", "evidence": [ { "id": "A0A4X1UE49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49/entry#names_and_taxonomy" } ] }, { "name": "cyclin-dependent kinase 14 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020958022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958022" } ] } ], "function": [ { "annotation": "Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A6V7", "url": "https://www.uniprot.org/uniprotkb/A0A287A6V7#function" }, { "database": "UniProtKB", "id": "ARBA00037568", "url": "https://www.uniprot.org/uniprotkb/ARBA00037568#function" }, { "database": "UniProtKB", "id": "A0A480V341", "url": "https://www.uniprot.org/uniprotkb/A0A480V341#function" }, { "database": "UniProtKB", "id": "A0A287ASJ9", "url": "https://www.uniprot.org/uniprotkb/A0A287ASJ9#function" }, { "database": "UniProtKB", "id": "F1S320", "url": "https://www.uniprot.org/uniprotkb/F1S320#function" }, { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CDK14", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49", "locus": { "chromosome": "9", "start_pos": 71310250, "end_pos": 70499873, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015307", "url": "https://www.ensembl.org/id/ENSSSCG00000015307" } ] } } ], "crossref": [ { "id": "A0A4X1UE49", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UE49", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015307", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015307", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07869", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07869", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515962", "url": "https://www.ncbi.nlm.nih.gov/gene/100515962", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515962", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515962", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MCDLLDS", "url": "https://omabrowser.org/oma/group/MCDLLDS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A480V341", "url": "https://www.orthodb.org/?gene=A0A480V341", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056:SF154", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF154", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020958022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A6V7", "url": "https://www.uniprot.org/uniprotkb/A0A287A6V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A6V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A6V7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASJ9", "url": "https://www.uniprot.org/uniprotkb/A0A287ASJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ASJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480V341", "url": "https://www.uniprot.org/uniprotkb/A0A480V341", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480V341-1", "url": "https://www.uniprot.org/uniprotkb/A0A480V341-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UE49-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S320", "url": "https://www.uniprot.org/uniprotkb/F1S320", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S320-1", "url": "https://www.uniprot.org/uniprotkb/F1S320-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTRNCPGMDSMIKPLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSAGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPENVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESTRAFGKNNSYGKSLSNSKH", "length": 423, "header": "tr|A0A4X1UE49-1|A0A4X1UE49_PIG Isoform 1 of Cyclin-dependent kinase 14 OS=Sus scrofa OX=9823 GN=CDK14 PE=3 SV=1 CANONICAL=A0A4X1UE49-1" }, "isoforms": [ { "isoform_ac": "A0A287A6V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49/entry#A0A287A6V7-1", "sequence": { "sequence": "MLALTLRPPLLAKSLLKFGGTPAPARVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPENVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESTRAFGKNNSYGKSLSNSKH", "length": 340, "header": "tr|A0A287A6V7-1|A0A4X1UE49_PIG Computationally mapped isoform of Cyclin-dependent kinase 14 OS=Sus scrofa OX=9823 GN=CDK14 PE=3 SV=1 CANONICAL=A0A4X1UE49-1" }, "locus": { "chromosome": "9", "start_pos": 71213432, "end_pos": 70821366, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040937.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040937.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039680.1", "url": "https://www.ensembl.org/id/ENSSSCP00000039680.1" } ] } }, { "isoform_ac": "A0A287ASJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49/entry#A0A287ASJ9-1", "sequence": { "sequence": "MHGYFGCNAAAEPGYSAFLGTPQICVTKMSTRNCPGMDSMIKPLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSAGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPENVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESTRAFGKNNSYGKSLSNSKH", "length": 451, "header": "tr|A0A287ASJ9-1|A0A4X1UE49_PIG Computationally mapped isoform of Cyclin-dependent kinase 14 OS=Sus scrofa OX=9823 GN=CDK14 PE=3 SV=1 CANONICAL=A0A4X1UE49-1" }, "locus": { "chromosome": "9", "start_pos": 71213432, "end_pos": 70798421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040722.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040722.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047055.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047055.2" } ] } }, { "isoform_ac": "A0A480V341-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49/entry#A0A480V341-1", "sequence": { "sequence": "MCDLIEPQPAEKIGKMKKLRRTLSDSFSRIALKKDDTTFDEICVTKMSTRNCPGMDSMIKPLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSAGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPENVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESTRAFGKNNSYGKSLSNSKH", "length": 469, "header": "tr|A0A480V341-1|A0A4X1UE49_PIG Computationally mapped isoform of Cyclin-dependent kinase 14 OS=Sus scrofa OX=9823 GN=CDK14 PE=3 SV=1 CANONICAL=A0A4X1UE49-1" }, "locus": { "chromosome": "9", "start_pos": 71213432, "end_pos": 70678621, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100617.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100617.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076926.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076926.1" } ] } }, { "isoform_ac": "A0A4X1UE49-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49/entry#A0A4X1UE49-1", "sequence": { "sequence": "MSTRNCPGMDSMIKPLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSAGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPENVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESTRAFGKNNSYGKSLSNSKH", "length": 423, "header": "tr|A0A4X1UE49-1|A0A4X1UE49_PIG Isoform 1 of Cyclin-dependent kinase 14 OS=Sus scrofa OX=9823 GN=CDK14 PE=3 SV=1 CANONICAL=A0A4X1UE49-1" }, "locus": { "chromosome": "9", "start_pos": 71213432, "end_pos": 70821212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040409.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040409.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041168.3", "url": "https://www.ensembl.org/id/ENSSSCP00000041168.3" } ] } }, { "isoform_ac": "F1S320-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49/entry#F1S320-1", "sequence": { "sequence": "MYCTEKLSDSFSRIALKKDDTTFDEICVTKMSTRNCPGMDSMIKPLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSAGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPENVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESTRAFGKNNSYGKSLSNSKH", "length": 453, "header": "tr|F1S320-1|A0A4X1UE49_PIG Computationally mapped isoform of Cyclin-dependent kinase 14 OS=Sus scrofa OX=9823 GN=CDK14 PE=3 SV=3 CANONICAL=A0A4X1UE49-1" }, "locus": { "chromosome": "9", "start_pos": 71213432, "end_pos": 70555683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016680.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016680.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016234.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016234.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A6V7", "url": "https://www.uniprot.org/uniprotkb/A0A287A6V7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515962", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515962", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A7V5-1", "protein_name": "Cyclin-dependent kinase 14", "gene_name": "Cdk14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLEQPCIANQYLSGETVCSGLPGQHMRGSFGCNAAAEPVHSAFLGTPQICVTKMSTRNCQGMDSVIKHLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKSSAAGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTVYSSKSLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH", "length": 477 }, "evidence": [ { "id": "A0A4X1UE49", "url": "https://omabrowser.org/oma/group/A0A4X1UE49/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XQ97-1", "protein_name": "Cyclin-dependent kinase 14", "gene_name": "CDK14", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRAVQSKFLEPYLECAWLEQDWQGRAACVAGLCASHAWSPQRQEPEICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQSSFDPFEKPTNQVKRVHSENNACINFKTSSAGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPENVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTQYSPKNLRQAWNKLSYVNHAEDLASKLLQCFPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQAETGESMRVFGKNNSYGKGVSNSKH", "length": 474 }, "evidence": [ { "id": "A0A4X1UE49", "url": "https://omabrowser.org/oma/group/A0A4X1UE49/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9SX77-1", "protein_name": "Cyclin-dependent kinase 14", "gene_name": "CDK14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MCDLIEPQPAEKIGKMKKLRRTLSDSFSRIALKKEDTTFEEICVTKMSTRNCPGMDSVIKPLDTIPEDKKVRVQRTQSTFDPFEKPTNQVKRVHSENNACINFNKSSSAGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRTFGKNNSYGKSLSNSKH", "length": 470 }, "evidence": [ { "id": "A0A4X1UE49", "url": "https://omabrowser.org/oma/group/A0A4X1UE49/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M9PE01-1", "protein_name": "cyclin-dependent kinase", "gene_name": "Eip63E", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATTTTTTTTTGATNAKDGVTMREKKGGALQKLKKRLSHSFGRLTISREDGDESTHHHHHHHHHRGGHGGHHNHGNKVPYNGYNSEEYLDRLEPNGNIPADKTNCRYGAQESAKNDNNKPQDWRSTDSTDHHDRVQRQLSVSSDSKLLDEDIREEMKYHSHVVMRPKKPPRPKSEVFLNKQETHPRRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYFAQLPKKLYELPDETSIFTVEGVQLYTEPNRQNKXKLKQVLSVDGVRFYC", "length": 538 }, "evidence": [ { "id": "A0A4X1UE49", "url": "https://omabrowser.org/oma/group/A0A4X1UE49/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O35495-1", "protein_name": "Cyclin-dependent kinase 14", "gene_name": "Cdk14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCDLIEPQPAEKIGKMKKLRRTLSESFSRIALKKEDTTFDEICVTKMSTRNCQGTDSVIKHLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKSSSAGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTVYSSKSLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH", "length": 469 }, "evidence": [ { "id": "A0A4X1UE49", "url": "https://omabrowser.org/oma/group/A0A4X1UE49/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O94921-1", "protein_name": "Cyclin-dependent kinase 14", "gene_name": "CDK14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCDLIEPQPAEKIGKMKKLRRTLSESFSRIALKKDDTTFDEICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH", "length": 469 }, "evidence": [ { "id": "A0A4X1UE49", "url": "https://omabrowser.org/oma/group/A0A4X1UE49/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030332", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" }, { "name": "cytoplasmic cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000308", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" }, { "name": "regulation of cell cycle phase transition", "id": "GO:1901987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901987", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE49", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UE49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE49" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 373, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 411, "end_pos": 413 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UGB0-1", "uniprot_ac": "A0A4X1UGB0", "uniprot_id": "A0A4X1UGB0_PIG", "mass": { "chemical_mass": 29581.0, "monoisotopic_mass": 29581.0 }, "refseq": {}, "gene_names": [ { "name": "CA13", "type": "recommended", "evidence": [ { "id": "A0A4X1UGB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0" } ] } ], "protein_names": [ { "name": "Carbonic anhydrase", "type": "recommended", "evidence": [ { "id": "A0A4X1UGB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0/entry#names_and_taxonomy" } ] }, { "name": "4.2.1.1", "type": "synonym", "evidence": [ { "id": "A0A4X1UGB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Reversible hydration of carbon dioxide.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A767", "url": "https://www.uniprot.org/uniprotkb/A0A287A767#function" }, { "database": "UniProtKB", "id": "RU367011", "url": "https://www.uniprot.org/uniprotkb/RU367011#function" }, { "database": "UniProtKB", "id": "A0A8D0N3G7", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N3G7#function" }, { "database": "UniProtKB", "id": "A0A4X1UGB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CA13", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0", "locus": { "chromosome": "4", "start_pos": 51408184, "end_pos": 51468973, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006143", "url": "https://www.ensembl.org/id/ENSSSCG00000006143" } ] } } ], "crossref": [ { "id": "A0A4X1UGB0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UGB0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006143", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006143", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152714", "url": "https://www.ncbi.nlm.nih.gov/gene/100152714", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152714", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152714", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VPREAQY", "url": "https://omabrowser.org/oma/group/VPREAQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UGB0", "url": "https://www.orthodb.org/?gene=A0A4X1UGB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952:SF81", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952:SF81", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1475029", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475029", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "10748", "url": "https://www.rhea-db.org/rhea/10748", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A767", "url": "https://www.uniprot.org/uniprotkb/A0A287A767", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A767-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A767-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UGB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UGB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0N3G7", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N3G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0N3G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0N3G7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRFSWGYGEHNGPVHWNEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFSVDFDDTEDKSVLRGGPLTGSYRLRQFHLHWGSADDHGSEHVVDGVKYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEHNSQLQKITDILDSIKEKGKQTRFTNFDPLSLLPPSWDYWTYPGSLTVPPLLESVTWIILKQPINISSQQLATFRTLLCTKEGEEAAFLLSNHRPLQPLKGRKVRASFH", "length": 262, "header": "tr|A0A4X1UGB0-1|A0A4X1UGB0_PIG Isoform 1 of Carbonic anhydrase OS=Sus scrofa OX=9823 GN=CA13 PE=1 SV=1 CANONICAL=A0A4X1UGB0-1" }, "isoforms": [ { "isoform_ac": "A0A287A767-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0/entry#A0A287A767-1", "sequence": { "sequence": "DHPYAEISPTHRPSPTHRPEYNSPSSAHTRSEAPPPGPVHWNEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFSVDFDDTEDKSVLRGGPLTGSYRLRQFHLHWGSADDHGSEHVVDGVKYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEHNSQLQKITDILDSIKEKGKQTRFTNFDPLSLLPPSWDYWTYPGSLTVPPLLESVTWIILKQPINISSQQLATFRTLLCTKEGEEAAFLLSNHRPLQPLKGRKVRASFH", "length": 286, "header": "tr|A0A287A767-1|A0A4X1UGB0_PIG Computationally mapped isoform of Carbonic anhydrase OS=Sus scrofa OX=9823 GN=CA13 PE=1 SV=1 CANONICAL=A0A4X1UGB0-1" }, "locus": { "chromosome": "4", "start_pos": 51468961, "end_pos": 51409612, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060972.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060972.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039659.1", "url": "https://www.ensembl.org/id/ENSSSCP00000039659.1" } ] } }, { "isoform_ac": "A0A4X1UGB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0/entry#A0A4X1UGB0-1", "sequence": { "sequence": "MSRFSWGYGEHNGPVHWNEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFSVDFDDTEDKSVLRGGPLTGSYRLRQFHLHWGSADDHGSEHVVDGVKYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEHNSQLQKITDILDSIKEKGKQTRFTNFDPLSLLPPSWDYWTYPGSLTVPPLLESVTWIILKQPINISSQQLATFRTLLCTKEGEEAAFLLSNHRPLQPLKGRKVRASFH", "length": 262, "header": "tr|A0A4X1UGB0-1|A0A4X1UGB0_PIG Isoform 1 of Carbonic anhydrase OS=Sus scrofa OX=9823 GN=CA13 PE=1 SV=1 CANONICAL=A0A4X1UGB0-1" }, "locus": { "chromosome": "4", "start_pos": 51449051, "end_pos": 51409612, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006736.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006736.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006553.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006553.4" } ] } }, { "isoform_ac": "A0A8D0N3G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0/entry#A0A8D0N3G7-1", "sequence": { "sequence": "MSRFSWGYGEHNGPVHWNEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFSVDFDDTEDKSVLRGGPLTGSYRLRQFHLHWGSADDHGSEHVVDGVKYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEHNSQLQKITDILDSIKEKGKQTRFTNFDPLSLLPPSWDYWTYPGSLTVPPLLESVTWIILKQPINISSQQLLFRAGPSACLYLSPSPSLELLPLYEGPISNFSPWGVEHIQHLLIFSLG", "length": 272, "header": "tr|A0A8D0N3G7-1|A0A4X1UGB0_PIG Computationally mapped isoform of Carbonic anhydrase OS=Sus scrofa OX=9823 GN=CA13 PE=1 SV=1 CANONICAL=A0A4X1UGB0-1" }, "locus": { "chromosome": "4", "start_pos": 51449051, "end_pos": 51419946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057817.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057817.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048222.3", "url": "https://www.ensembl.org/id/ENSSSCP00000048222.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A767", "url": "https://www.uniprot.org/uniprotkb/A0A287A767" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152714", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152714", "resource": "KEGG Pathway" }, { "id": "R-SSC-1475029", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475029", "resource": "Reactome", "description": "Reversible hydration of carbon dioxide" } ], "orthologs": [ { "uniprot_canonical_ac": "B5DFG6-1", "protein_name": "Carbonic anhydrase", "gene_name": "Ca13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARLSWGYDEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKIISNSGHSFNVDFDDTEDKSVLRGGPLTGSYRLRQFHLHWGSADDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNFDPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAAFLLSNHRPPQPLKGRRVRASFY", "length": 262 }, "evidence": [ { "id": "A0A4X1UGB0", "url": "https://omabrowser.org/oma/group/A0A4X1UGB0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3MX64-1", "protein_name": "Carbonic anhydrase", "gene_name": "CA13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGFSWGYGERDGPVHWNEFFPIADGDQQSPIEIKTKEVRYDSSLRPLGIKYDASSAKIISNSGHSFNVDFDDTDDKSVLRGGPLTGSYRLRQFHLHWGSTDDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGIFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNFDPVCLLPPCRDYWTYPGSLTVPPLLESVTWIILKQPINISSQQLAAFRTLLCSREGETAAFLLSNHRPPQPLKGRKVRASFR", "length": 262 }, "evidence": [ { "id": "A0A4X1UGB0", "url": "https://omabrowser.org/oma/group/A0A4X1UGB0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q92051-1", "protein_name": "Carbonic anhydrase", "gene_name": "cahz", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAHAWGYGPADGPESWAESFPIANGPRQSPIDIVPTQAQHDPSLKHLKLKYDPATTKSILNNGHSFQVDFVDDDNSSTLAGGPITGIYRLRQFHFHWGSSDDKGSEHTIAGTKFPCELHLVHWNTKYPNFGEAASKPDGLAVVGVFLKIGAANPRLQKVLDALDDIKSKGRQTTFANFDPKTLLPASLDYWTYEGSLTTPPLLESVTWIVLKEPISVSPAQMAKFRSLLFSSEGETPCCMVDNYRPPQPLKGRKVRASFK", "length": 260 }, "evidence": [ { "id": "A0A4X1UGB0", "url": "https://omabrowser.org/oma/group/A0A4X1UGB0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D6N1-1", "protein_name": "Carbonic anhydrase 13", "gene_name": "Ca13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARLSWGYGEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKIISNSGHSFNVDFDDTEDKSVLRGGPLTGNYRLRQFHLHWGSADDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNFDPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAAFLLSNHRPPQPLKGRRVRASFY", "length": 262 }, "evidence": [ { "id": "A0A4X1UGB0", "url": "https://omabrowser.org/oma/group/A0A4X1UGB0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10748", "name": "", "equation": "hydrogencarbonate + H(+) = CO2 + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10748", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10748" } ] }, { "id": "R-SSC-1475022", "name": "Carbonic anhydrase dehydrates bicarbonate (cytosol)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1475022", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475022" } ] }, { "id": "R-SSC-1475026", "name": "Carbonic anhydrase hydrates carbon dioxide (cytosol)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1475026", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475026" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UGB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGB0" }, { "id": "PS51144", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51144" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-carbonic anhydrase", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 261, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1V3K1-1", "uniprot_ac": "A0A4X1V3K1", "uniprot_id": "A0A4X1V3K1_PIG", "mass": { "chemical_mass": 23258.0, "monoisotopic_mass": 23258.0 }, "refseq": { "ac": "NP_001231648", "name": "synaptosomal-associated protein 23", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231648" }, "gene_names": [ { "name": "SNAP23", "type": "recommended", "evidence": [ { "id": "A0A4X1V3K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ] }, { "name": "SNAP23", "type": "synonym", "evidence": [ { "id": "NP_001231648", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231648" } ] } ], "protein_names": [ { "name": "Synaptosomal-associated protein", "type": "recommended", "evidence": [ { "id": "A0A4X1V3K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1/entry#names_and_taxonomy" } ] }, { "name": "synaptosomal-associated protein 23", "type": "synonym", "evidence": [ { "id": "NP_001231648", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231648" } ] }, { "name": "synaptosomal-associated protein, 23kDa", "type": "synonym", "evidence": [ { "id": "NP_001231648", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231648" } ] } ], "function": [ { "annotation": "Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AHK8", "url": "https://www.uniprot.org/uniprotkb/A0A287AHK8#function" }, { "database": "UniProtKB", "id": "ARBA00053876", "url": "https://www.uniprot.org/uniprotkb/ARBA00053876#function" }, { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1#function" } ] }, { "annotation": "MRNA levels of BSCL2 and SNAP23, but not COPA, increased during adipocyte differentiation. Redistribution of SNAP23 protein to different cellular compartments was observed when comparing undifferentiated mesenchymal stem cells and differentiated adipocytes.", "evidence": [ { "database": "RefSeq", "id": "NP_001231648", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231648" }, { "database": "PubMed", "id": "27108337", "url": "https://glygen.org/publication/PubMed/27108337" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SNAP23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1", "locus": { "chromosome": "1", "start_pos": 128847931, "end_pos": 128888947, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000038735", "url": "https://www.ensembl.org/id/ENSSSCG00000038735" } ] } } ], "crossref": [ { "id": "A0A4X1V3K1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1V3K1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000038735", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000038735", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15884", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15884", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15895", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15895", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512755", "url": "https://www.ncbi.nlm.nih.gov/gene/100512755", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ADMTNPF", "url": "https://omabrowser.org/oma/group/ADMTNPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287AHK8", "url": "https://www.orthodb.org/?gene=A0A287AHK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1V3K1", "url": "https://www.orthodb.org/?gene=A0A4X1V3K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19305", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19305", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19305:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19305:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1236974", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1236974", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-199992", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-199992", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013026", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013026", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001231648", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231648", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AHK8", "url": "https://www.uniprot.org/uniprotkb/A0A287AHK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AHK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AHK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B5Z0", "url": "https://www.uniprot.org/uniprotkb/A0A287B5Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B5Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B5Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BI18", "url": "https://www.uniprot.org/uniprotkb/A0A287BI18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BI18-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BI18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V3K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QID9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QID9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QID9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QID9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRA2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0UQ60", "url": "https://www.uniprot.org/uniprotkb/A0A8D0UQ60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0UQ60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0UQ60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNLSAEELQLRANQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCYRTKNFESGKAYKATWGDGGDNSPSNVVSKQPGRVTNGQPQQAATGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIEAQNRQIERITEKADTNKDRIDNANARAKKLIDS", "length": 211, "header": "tr|A0A4X1V3K1-1|A0A4X1V3K1_PIG Isoform 1 of Synaptosomal-associated protein OS=Sus scrofa OX=9823 GN=SNAP23 PE=1 SV=1 CANONICAL=A0A4X1V3K1-1" }, "isoforms": [ { "isoform_ac": "A0A287AHK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1/entry#A0A287AHK8-1", "sequence": { "sequence": "MDNLSAEELQLRANQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCYRFSDVGCFCETRTKNFESGKAYKATWGDGGDNSPSNVVSKQPGRVTNGQPQQAATGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIEAQNRQIERITEKADTNKDRIDNANARAKKLIDS", "length": 222, "header": "tr|A0A287AHK8-1|A0A4X1V3K1_PIG Computationally mapped isoform of Synaptosomal-associated protein OS=Sus scrofa OX=9823 GN=SNAP23 PE=1 SV=1 CANONICAL=A0A4X1V3K1-1" }, "locus": { "chromosome": "1", "start_pos": 128866387, "end_pos": 128850918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037285.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037285.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043345.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043345.1" } ] } }, { "isoform_ac": "A0A287B5Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1/entry#A0A287B5Z0-1", "sequence": { "sequence": "MDNLSAEELQLRANQVTDEVSSQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCYRTKNFESGKAYKATWGDGGDNSPSNVVSKQPGRVTNGQPQQAATGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIEAQNRQIERITEKADTNKDRIDNANARAKKLIDS", "length": 199, "header": "tr|A0A287B5Z0-1|A0A4X1V3K1_PIG Computationally mapped isoform of Synaptosomal-associated protein OS=Sus scrofa OX=9823 GN=SNAP23 PE=1 SV=1 CANONICAL=A0A4X1V3K1-1" }, "locus": { "chromosome": "1", "start_pos": 128866387, "end_pos": 128850918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048710.2", "url": "https://www.ensembl.org/id/ENSSSCT00000048710.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051497.2", "url": "https://www.ensembl.org/id/ENSSSCP00000051497.2" } ] } }, { "isoform_ac": "A0A287BI18-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1/entry#A0A287BI18-1", "sequence": { "sequence": "MDNLSAEELQLRANQVTDEVSSQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCYSITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIEAQNRQIERITEKADTNKDRIDNANARAKKLIDS", "length": 146, "header": "tr|A0A287BI18-1|A0A287BI18_PIG Computationally mapped isoform of Synaptosome associated protein 23 OS=Sus scrofa OX=9823 GN=SNAP23 PE=1 SV=2 CANONICAL=A0A4X1V3K1-1" }, "locus": { "chromosome": "1", "start_pos": 128866387, "end_pos": 128850918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046474.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046474.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055712.3", "url": "https://www.ensembl.org/id/ENSSSCP00000055712.3" } ] } }, { "isoform_ac": "A0A4X1V3K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1/entry#A0A4X1V3K1-1", "sequence": { "sequence": "MDNLSAEELQLRANQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCYRTKNFESGKAYKATWGDGGDNSPSNVVSKQPGRVTNGQPQQAATGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIEAQNRQIERITEKADTNKDRIDNANARAKKLIDS", "length": 211, "header": "tr|A0A4X1V3K1-1|A0A4X1V3K1_PIG Isoform 1 of Synaptosomal-associated protein OS=Sus scrofa OX=9823 GN=SNAP23 PE=1 SV=1 CANONICAL=A0A4X1V3K1-1" }, "locus": { "chromosome": "1", "start_pos": 128866387, "end_pos": 128850918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045675.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045675.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050427.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050427.1" } ] } }, { "isoform_ac": "A0A5G2QID9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1/entry#A0A5G2QID9-1", "sequence": { "sequence": "MDNLSAEELQLRANQVTDESLESTRRILGLAIEYWNMAGKVSSP", "length": 44, "header": "tr|A0A5G2QID9-1|A0A4X1V3K1_PIG Computationally mapped isoform of Synaptosomal-associated protein OS=Sus scrofa OX=9823 GN=SNAP23 PE=1 SV=1 CANONICAL=A0A4X1V3K1-1" }, "locus": { "chromosome": "1", "start_pos": 128866387, "end_pos": 128865524, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073081.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073081.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063661.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063661.1" } ] } }, { "isoform_ac": "A0A5G2QRA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1/entry#A0A5G2QRA2-1", "sequence": { "sequence": "MDNLSAEELQLRANQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCYRLTPTKTVLTMPMPEQRNSLTAKVTAVLLYHMFTSLAPPS", "length": 128, "header": "tr|A0A5G2QRA2-1|A0A4X1V3K1_PIG Computationally mapped isoform of Synaptosomal-associated protein OS=Sus scrofa OX=9823 GN=SNAP23 PE=1 SV=1 CANONICAL=A0A4X1V3K1-1" }, "locus": { "chromosome": "1", "start_pos": 128866387, "end_pos": 128850863, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081485.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081485.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067447.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067447.1" } ] } }, { "isoform_ac": "A0A5G2RDV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1/entry#A0A5G2RDV3-1", "sequence": { "sequence": "MDNLSAEELQLRANQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCYRFNIRSRAQ", "length": 97, "header": "tr|A0A5G2RDV3-1|A0A4X1V3K1_PIG Computationally mapped isoform of Synaptosomal-associated protein OS=Sus scrofa OX=9823 GN=SNAP23 PE=1 SV=1 CANONICAL=A0A4X1V3K1-1" }, "locus": { "chromosome": "1", "start_pos": 128866387, "end_pos": 128859443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075271.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075271.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072665.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072665.1" } ] } }, { "isoform_ac": "A0A8D0UQ60-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1/entry#A0A8D0UQ60-1", "sequence": { "sequence": "MDNLSAEELQLRANQVTDEVSSQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCVDKSRPFSNKSKNFESGKAYKATWGDGGDNSPSNVVSKQPGRVTNGQPQQAATGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIEAQNRQIERITEKADTNKDRIDNANARAKKLIDS", "length": 200, "header": "tr|A0A8D0UQ60-1|A0A4X1V3K1_PIG Computationally mapped isoform of Synaptosomal-associated protein OS=Sus scrofa OX=9823 GN=SNAP23 PE=1 SV=1 CANONICAL=A0A4X1V3K1-1" }, "locus": { "chromosome": "1", "start_pos": 128866387, "end_pos": 128850918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037345.2", "url": "https://www.ensembl.org/id/ENSSSCT00000037345.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031818.2", "url": "https://www.ensembl.org/id/ENSSSCP00000031818.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Expression of genes involved in lipid droplet formation (BSCL2, SNAP23 and COPA) during porcine in vitro adipogenesis.", "journal": "Journal of applied genetics", "date": "2016-11", "authors": "Kociucka Beata, Flisikowska Tatiana, Mr\u00f3z Dariusz, Szczerbal Izabela", "evidence": [ { "database": "RefSeq", "id": "NP_001231648", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231648" } ], "reference": [ { "type": "PubMed", "id": "27108337", "url": "https://glygen.org/publication/PubMed/27108337" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QID9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QID9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1236974", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1236974", "resource": "Reactome", "description": "ER-Phagosome pathway" }, { "id": "R-SSC-199992", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-199992", "resource": "Reactome", "description": "trans-Golgi Network Vesicle Budding" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-SSC-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-SSC-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-SSC-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-SSC-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JU21-1", "protein_name": "Synaptosomal-associated protein", "gene_name": "Snap23", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDNLSSEEIQLRAHQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCNRAKKFESGKNYKATWGDGGDNSPSNVVCKQPGRVTNGQPQQTTGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIDAQNQQIQRITEKADTNKDRIDIANTRAKKLIDS", "length": 210 }, "evidence": [ { "id": "A0A4X1V3K1", "url": "https://omabrowser.org/oma/group/A0A4X1V3K1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BRL4-1", "protein_name": "Synaptosomal-associated protein", "gene_name": "SNAP23", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAELSPEEIQLRANQVTDESLESTRRILGLAIESHDVGVRTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCNRTKNFETTKAYRTTWGDGTENSADHVISMQPRSINQQQPHNSRGPSGGYITRITNDAREDEMDENLTQVGNILGNLKNMALDMGNEIDAQNKQIDRINVKADTNRDRIEQANIRAKKLIDN", "length": 209 }, "evidence": [ { "id": "A0A4X1V3K1", "url": "https://omabrowser.org/oma/group/A0A4X1V3K1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O09044-1", "protein_name": "Synaptosomal-associated protein 23", "gene_name": "Snap23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNLSPEEVQLRAHQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCICPCNRTKNFESGKNYKATWGDGGDNSPSNVVSKQPSRITNGQPQQTTGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIDAQNQQIQKITEKADTNKNRIDIANTRAKKLIDS", "length": 210 }, "evidence": [ { "id": "A0A4X1V3K1", "url": "https://omabrowser.org/oma/group/A0A4X1V3K1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O70377-1", "protein_name": "Synaptosomal-associated protein 23", "gene_name": "Snap23", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDLSPEEIQLRAHQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCNRTKNFESGKNYKATWGDGGDSSPSNVVSKQPSRITNGQPQQTTGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIDAQNQQIQKITEKADTNKNRIDIANTRAKKLIDS", "length": 210 }, "evidence": [ { "id": "A0A4X1V3K1", "url": "https://omabrowser.org/oma/group/A0A4X1V3K1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9S7P9-1", "protein_name": "SNAP25 homologous protein SNAP33", "gene_name": "SNAP33", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFGLRKSPANLPKHNSVDLKSSKPNPFDSDDESDNKHTLNPSKRTTSEPSLADMTNPFGGERVQKGDSSSSKQSLFSNSKYQYKNNFRDSGGIENQSVQELEGYAVYKAEETTKSVQGCLKVAEDIRSDATRTLVMLHDQGEQITRTHHKAVEIDHDLSRGEKLLGSLGGMFSKTWKPKKTRPINGPVVTRDDSPTRRVNHLEKREKLGLNSAPRGQSRTREPLPESADAYQRVEMEKAKQDDGLSDLSDILGELKNMAVDMGSEIEKQNKGLDHLHDDVDELNFRVQQSNQRGRRLLGK", "length": 300 }, "evidence": [ { "id": "A0A4X1V3K1", "url": "https://omabrowser.org/oma/group/A0A4X1V3K1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" }, { "name": "specific granule", "id": "GO:0042581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042581", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" }, { "name": "azurophil granule", "id": "GO:0042582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042582", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" }, { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "histamine secretion by mast cell", "id": "GO:0002553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002553", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" }, { "name": "synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031629", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" }, { "name": "synaptic vesicle priming", "id": "GO:0016082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016082", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V3K1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1V3K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V3K1" }, { "id": "PS50192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-SNARE coiled-coil homology", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 76, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U069-1", "uniprot_ac": "A0A4X1U069", "uniprot_id": "A0A4X1U069_PIG", "mass": { "chemical_mass": 70755.0, "monoisotopic_mass": 70755.0 }, "refseq": { "ac": "XP_020954639", "name": "vacuolar protein sorting-associated protein 33B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954639" }, "gene_names": [ { "name": "VPS33B", "type": "recommended", "evidence": [ { "id": "A0A4X1U069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ] }, { "name": "VPS33B", "type": "synonym", "evidence": [ { "id": "XP_020954639", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954639" } ] } ], "protein_names": [ { "name": "Vacuolar protein sorting-associated protein 33B", "type": "recommended", "evidence": [ { "id": "A0A4X1U069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069/entry#names_and_taxonomy" } ] }, { "name": "vacuolar protein sorting-associated protein 33B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020954639", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954639" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "VPS33B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069", "locus": { "chromosome": "7", "start_pos": 55865716, "end_pos": 55840607, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000033954", "url": "https://www.ensembl.org/id/ENSSSCG00000033954" } ] } } ], "crossref": [ { "id": "A0A4X1U069", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U069", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000033954", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033954", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110261556", "url": "https://www.ncbi.nlm.nih.gov/gene/110261556", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110261556", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261556", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NWIGITR", "url": "https://omabrowser.org/oma/group/NWIGITR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U069", "url": "https://www.orthodb.org/?gene=A0A4X1U069", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11679", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11679", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00995", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00995", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020954639", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954639", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BEJ4", "url": "https://www.uniprot.org/uniprotkb/A0A287BEJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BEJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BEJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U069-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0ZEK8", "url": "https://www.uniprot.org/uniprotkb/A0A8D0ZEK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0ZEK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0ZEK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1C8W3", "url": "https://www.uniprot.org/uniprotkb/A0A8D1C8W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1C8W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1C8W3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFPHRPDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPAFSSSEQLCFLVRPRIKNMRYIANLVNADKLAGRTRKYKVIFSPQKFYACEMVLEEEGIYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRYAKMSHELWRKLEEEEDGETKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFHEIRNEHFSNVFSFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVESKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLERRGWQGLDEVVRLLNCSELVFTDRSKEDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAVTNSARLMEAMSEVKA", "length": 617, "header": "tr|A0A4X1U069-1|A0A4X1U069_PIG Isoform 1 of Vacuolar protein sorting-associated protein 33B OS=Sus scrofa OX=9823 GN=VPS33B PE=3 SV=1 CANONICAL=A0A4X1U069-1" }, "isoforms": [ { "isoform_ac": "A0A287BEJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069/entry#A0A287BEJ4-1", "sequence": { "sequence": "MAFPHRPDAPELPDFSMLKRLARDQLIYLLEQADERAASGMMTWKLDDMGLGLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPAFSSSEQLCFLVRPRIKNMRYIANLVNADKLAGRTRKYKVIFSPQKFYACEMVLEEEGIYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRYAKMSHELWRKLEEEEDGETKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFHEIRNEHFSNVFSFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVESKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLERRGWQGLDEVVRLLNCSELVFTDRSKEDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAVTNSARLMEAMSEVKA", "length": 637, "header": "tr|A0A287BEJ4-1|A0A4X1U069_PIG Computationally mapped isoform of Vacuolar protein sorting-associated protein 33B OS=Sus scrofa OX=9823 GN=VPS33B PE=3 SV=2 CANONICAL=A0A4X1U069-1" }, "locus": { "chromosome": "7", "start_pos": 55864755, "end_pos": 55840957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064224.2", "url": "https://www.ensembl.org/id/ENSSSCT00000064224.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054969.2", "url": "https://www.ensembl.org/id/ENSSSCP00000054969.2" } ] } }, { "isoform_ac": "A0A4X1U069-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069/entry#A0A4X1U069-1", "sequence": { "sequence": "MAFPHRPDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPAFSSSEQLCFLVRPRIKNMRYIANLVNADKLAGRTRKYKVIFSPQKFYACEMVLEEEGIYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRYAKMSHELWRKLEEEEDGETKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFHEIRNEHFSNVFSFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVESKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLERRGWQGLDEVVRLLNCSELVFTDRSKEDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAVTNSARLMEAMSEVKA", "length": 617, "header": "tr|A0A4X1U069-1|A0A4X1U069_PIG Isoform 1 of Vacuolar protein sorting-associated protein 33B OS=Sus scrofa OX=9823 GN=VPS33B PE=3 SV=1 CANONICAL=A0A4X1U069-1" }, "locus": { "chromosome": "7", "start_pos": 55864755, "end_pos": 55840957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068938.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068938.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072482.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072482.2" } ] } }, { "isoform_ac": "A0A8D0ZEK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069/entry#A0A8D0ZEK8-1", "sequence": { "sequence": "MMTWKLDDMGLGLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPAFSSSEQLCFLVRPRIKNMRYIANLVNADKLAGRTRKYKVIFSPQKFYACEMVLEEEGIYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRYAKMSHELWRKLEEEEDGETKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFHEIRNEHFSNVFSFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVESKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLERRGWQGLDEVVRLLNCSELVFTDRSKEDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAVTNSARLMEAMSEVKA", "length": 597, "header": "tr|A0A8D0ZEK8-1|A0A4X1U069_PIG Computationally mapped isoform of Vacuolar protein sorting-associated protein 33B OS=Sus scrofa OX=9823 GN=VPS33B PE=3 SV=1 CANONICAL=A0A4X1U069-1" }, "locus": { "chromosome": "7", "start_pos": 55864755, "end_pos": 55845460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087557.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087557.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072218.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072218.1" } ] } }, { "isoform_ac": "A0A8D1C8W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069/entry#A0A8D1C8W3-1", "sequence": { "sequence": "MAFPHRPDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPAFSSSEQLCFLVRPRIKNMRYIANLVNADKLAGRTRKYKVIFSPQKFYACEMVLEEEGIYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRYAKMSHELWRKLEEEEDGETKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFHEIRNEHFSNVFSFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVESKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLERRGWQGLDEVVRLLNCSELVFTGYRFIFLTTAVTNSARLMEAMSEVKA", "length": 578, "header": "tr|A0A8D1C8W3-1|A0A4X1U069_PIG Computationally mapped isoform of Vacuolar protein sorting-associated protein 33B OS=Sus scrofa OX=9823 GN=VPS33B PE=3 SV=1 CANONICAL=A0A4X1U069-1" }, "locus": { "chromosome": "7", "start_pos": 55864755, "end_pos": 55840957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065027.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065027.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054639.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054639.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BEJ4", "url": "https://www.uniprot.org/uniprotkb/A0A287BEJ4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110261556", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261556", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q2HJ18-1", "protein_name": "Vacuolar protein sorting-associated protein 33B", "gene_name": "VPS33B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFPHRPDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPALSSSEQLCFLVRPRIKNMRYIASLVNADKMAGRTRKYKVIFSPQKFYACEMVLEEEGVYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTLAQALHLLSTLYGPFPNCYGIGRCAKMSYELWKRLEEEEDGETKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFNEIRNEHFSNVFGFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTNYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFFNLRRAGLLTEQAPGDTLTAVESKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLERRGWQGLDEVVRLLNCSELAFTDMTKDDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAVTNSARLMEAMSEVKA", "length": 617 }, "evidence": [ { "id": "A0A4X1U069", "url": "https://omabrowser.org/oma/group/A0A4X1U069/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9H267-1", "protein_name": "Vacuolar protein sorting-associated protein 33B", "gene_name": "VPS33B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFPHRPDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPALSSNEQLCFLVRPRIKNMRYIASLVNADKLAGRTRKYKVIFSPQKFYACEMVLEEEGIYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRCAKMAYELWRNLEEEEDGETKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFNEIRNEHFSNVFGFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVESKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFGGAYVPLSCRIIEQVLERRSWQGLDEVVRLLNCSDFAFTDMTKEDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAVTNSARLMEAMSEVKA", "length": 617 }, "evidence": [ { "id": "A0A4X1U069", "url": "https://omabrowser.org/oma/group/A0A4X1U069/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "HOPS complex", "id": "GO:0030897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030897", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "platelet alpha granule", "id": "GO:0031091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031091", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "CORVET complex", "id": "GO:0033263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033263", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "platelet alpha granule organization", "id": "GO:0070889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070889", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "megakaryocyte development", "id": "GO:0035855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035855", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "membrane fusion", "id": "GO:0061025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061025", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "skin morphogenesis", "id": "GO:0043589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043589", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "melanosome localization", "id": "GO:0032400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032400", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "regulation of platelet aggregation", "id": "GO:0090330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090330", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U069", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U069" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 545, "end_pos": 547 }, { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UY00-1", "uniprot_ac": "A0A4X1UY00", "uniprot_id": "A0A4X1UY00_PIG", "mass": { "chemical_mass": 66227.0, "monoisotopic_mass": 66227.0 }, "refseq": {}, "gene_names": [ { "name": "PCSK2", "type": "recommended", "evidence": [ { "id": "A0A4X1UY00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00" } ] } ], "protein_names": [ { "name": "Neuroendocrine convertase 2", "type": "recommended", "evidence": [ { "id": "A0A4X1UY00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.94", "type": "synonym", "evidence": [ { "id": "A0A4X1UY00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00/entry#names_and_taxonomy" } ] }, { "name": "Prohormone convertase 2", "type": "synonym", "evidence": [ { "id": "A0A4X1UY00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00/entry#names_and_taxonomy" } ] }, { "name": "Proprotein convertase 2", "type": "synonym", "evidence": [ { "id": "A0A4X1UY00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A480EG12", "url": "https://www.uniprot.org/uniprotkb/A0A480EG12#function" }, { "database": "UniProtKB", "id": "ARBA00037494", "url": "https://www.uniprot.org/uniprotkb/ARBA00037494#function" }, { "database": "UniProtKB", "id": "A0A4X1UY00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UY00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PCSK2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00", "locus": { "chromosome": "17", "start_pos": 25923004, "end_pos": 25681197, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007083", "url": "https://www.ensembl.org/id/ENSSSCG00000007083" } ] } } ], "crossref": [ { "id": "A0A4X1UY00", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UY00", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000007083", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007083", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR42884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42884:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42884:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00082", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00082", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01483", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01483", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A480EG12", "url": "https://www.uniprot.org/uniprotkb/A0A480EG12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480EG12-1", "url": "https://www.uniprot.org/uniprotkb/A0A480EG12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UY00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UY00-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGGCVSQWKAAAGLLFCVTVFASAERPVFTNHFLVELHKGGEEEARQVAAEHGFGVRKVKRALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYSSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEWTLMLHGTQSAPYIDQVVRDYQSKLAMSKKEELEEELDEAVERSLKSILGKH", "length": 603, "header": "tr|A0A4X1UY00-1|A0A4X1UY00_PIG Isoform 1 of Neuroendocrine convertase 2 OS=Sus scrofa OX=9823 GN=PCSK2 PE=3 SV=1 CANONICAL=A0A4X1UY00-1" }, "isoforms": [ { "isoform_ac": "A0A480EG12-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00/entry#A0A480EG12-1", "sequence": { "sequence": "MKGGCVSQWKAAAGLLFCVTVFASAERPVFTNHFLVELHKGGEEEARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQRLERDPRVKRALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYSSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEWTLMLHGTQSAPYIDQVVRDYQSKLAMSKKEELEEELDEAVERSLKSILGKH", "length": 638, "header": "tr|A0A480EG12-1|A0A4X1UY00_PIG Computationally mapped isoform of Neuroendocrine convertase 2 OS=Sus scrofa OX=9823 GN=PCSK2 PE=3 SV=1 CANONICAL=A0A4X1UY00-1" }, "locus": { "chromosome": "17", "start_pos": 25920488, "end_pos": 25681451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007755.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007755.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007546.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007546.4" } ] } }, { "isoform_ac": "A0A4X1UY00-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00/entry#A0A4X1UY00-1", "sequence": { "sequence": "MKGGCVSQWKAAAGLLFCVTVFASAERPVFTNHFLVELHKGGEEEARQVAAEHGFGVRKVKRALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYSSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEWTLMLHGTQSAPYIDQVVRDYQSKLAMSKKEELEEELDEAVERSLKSILGKH", "length": 603, "header": "tr|A0A4X1UY00-1|A0A4X1UY00_PIG Isoform 1 of Neuroendocrine convertase 2 OS=Sus scrofa OX=9823 GN=PCSK2 PE=3 SV=1 CANONICAL=A0A4X1UY00-1" }, "locus": { "chromosome": "17", "start_pos": 25920488, "end_pos": 25681451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071806.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071806.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065655.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065655.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A480EG12", "url": "https://www.uniprot.org/uniprotkb/A0A480EG12" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UY00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UY00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UY00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UY00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UY00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00" } ], "pmid": "" }, { "name": "intracellular organelle lumen", "id": "GO:0070013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070013", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UY00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UY00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "peptide hormone processing", "id": "GO:0016486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016486", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UY00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00" } ], "pmid": "" }, { "name": "insulin processing", "id": "GO:0030070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030070", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UY00", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UY00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UY00" }, { "id": "PS51829", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51829" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "P/Homo B", "eco_id": "ECO_0000259", "start_pos": 426, "end_pos": 562, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 340, "end_pos": 342 }, { "start_pos": 479, "end_pos": 481 }, { "start_pos": 489, "end_pos": 491 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UU82-1", "uniprot_ac": "A0A4X1UU82", "uniprot_id": "A0A4X1UU82_PIG", "mass": { "chemical_mass": 65551.0, "monoisotopic_mass": 65551.0 }, "refseq": { "ac": "XP_013841392", "name": "CTP synthase 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841392" }, "gene_names": [ { "name": "CTPS2", "type": "recommended", "evidence": [ { "id": "A0A4X1UU82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" } ] }, { "name": "CTPS2", "type": "synonym", "evidence": [ { "id": "XP_013841392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841392" } ] } ], "protein_names": [ { "name": "CTP synthase", "type": "recommended", "evidence": [ { "id": "A0A4X1UU82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82/entry#names_and_taxonomy" } ] }, { "name": "6.3.4.2", "type": "synonym", "evidence": [ { "id": "A0A4X1UU82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82/entry#names_and_taxonomy" } ] }, { "name": "CTP synthase 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_013841392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841392" } ] }, { "name": "UTP--ammonia ligase", "type": "synonym", "evidence": [ { "id": "A0A4X1UU82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "CTP synthase involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.", "evidence": [ { "database": "UniProtKB", "id": "A0A480TY64", "url": "https://www.uniprot.org/uniprotkb/A0A480TY64#function" }, { "database": "UniProtKB", "id": "ARBA00094294", "url": "https://www.uniprot.org/uniprotkb/ARBA00094294#function" }, { "database": "UniProtKB", "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82#function" }, { "database": "UniProtKB", "id": "F1SQS3", "url": "https://www.uniprot.org/uniprotkb/F1SQS3#function" } ] }, { "annotation": "Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.", "evidence": [ { "database": "UniProtKB", "id": "A0A480TY64", "url": "https://www.uniprot.org/uniprotkb/A0A480TY64#function" }, { "database": "UniProtKB", "id": "RU810713", "url": "https://www.uniprot.org/uniprotkb/RU810713#function" }, { "database": "UniProtKB", "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82#function" }, { "database": "UniProtKB", "id": "F1SQS3", "url": "https://www.uniprot.org/uniprotkb/F1SQS3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CTPS2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82", "locus": { "chromosome": "X", "start_pos": 13049941, "end_pos": 13174568, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012146", "url": "https://www.ensembl.org/id/ENSSSCG00000012146" } ] } } ], "crossref": [ { "id": "A0A4X1UU82", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UU82", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012146", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012146", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01746", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01746", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03113", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03113", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100520595", "url": "https://www.ncbi.nlm.nih.gov/gene/100520595", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520595", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520595", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HAAMYCH", "url": "https://omabrowser.org/oma/group/HAAMYCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A480TY64", "url": "https://www.orthodb.org/?gene=A0A480TY64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UU82", "url": "https://www.orthodb.org/?gene=A0A4X1UU82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11550", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11550", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11550:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11550:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00117", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00117", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06418", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06418", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-499943", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-499943", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013841392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841392", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "26426", "url": "https://www.rhea-db.org/rhea/26426", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A480TY64", "url": "https://www.uniprot.org/uniprotkb/A0A480TY64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480TY64-1", "url": "https://www.uniprot.org/uniprotkb/A0A480TY64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UU82-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SQS3", "url": "https://www.uniprot.org/uniprotkb/F1SQS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SQS3-1", "url": "https://www.uniprot.org/uniprotkb/F1SQS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQATVPVDGHKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVKPEQVICIHDVSSTYRVPVLLEEQGIVKYFKERLDLPIGDSASNLLFKWRNMADRYERLQKTCSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEQTTETEDPVKFHEAWQKLCKADGVLVPGGFGIRGTLGKLQAISWARARKIPFLGVCLGMQLAVIEFARNCLNLKDADSTEFEPNARVPVVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRYEVNPSLINQLEQNDLSFVGQDVDGERMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLLRGCKLSSSDRYSDASDDSFSEPRIAELDIS", "length": 586, "header": "tr|A0A4X1UU82-1|A0A4X1UU82_PIG Isoform 1 of CTP synthase OS=Sus scrofa OX=9823 GN=CTPS2 PE=1 SV=1 CANONICAL=A0A4X1UU82-1" }, "isoforms": [ { "isoform_ac": "A0A480TY64-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82/entry#A0A480TY64-1", "sequence": { "sequence": "MRVRSLALLSGLRIWSCRKLHIISGCWHPATPLPMKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQATVPVDGHKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVKPEQVICIHDVSSTYRVPVLLEEQGIVKYFKERLDLPIGDSASNLLFKWRNMADRYERLQKTCSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEQTTETEDPVKFHEAWQKLCKADGVLVPGGFGIRGTLGKLQAISWARARKIPFLGVCLGMQLAVIEFARNCLNLKDADSTEFEPNARVPVVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRYEVNPSLINQLEQNDLSFVGQDVDGERMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLLRGCKLSSSDRYSDASDDSFSEPRIAELDIS", "length": 620, "header": "tr|A0A480TY64-1|A0A4X1UU82_PIG Computationally mapped isoform of CTP synthase OS=Sus scrofa OX=9823 GN=CTPS2 PE=1 SV=1 CANONICAL=A0A4X1UU82-1" }, "locus": { "chromosome": "X", "start_pos": 13172223, "end_pos": 13051968, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072435.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072435.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061342.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061342.1" } ] } }, { "isoform_ac": "A0A4X1UU82-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82/entry#A0A4X1UU82-1", "sequence": { "sequence": "MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQATVPVDGHKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVKPEQVICIHDVSSTYRVPVLLEEQGIVKYFKERLDLPIGDSASNLLFKWRNMADRYERLQKTCSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEQTTETEDPVKFHEAWQKLCKADGVLVPGGFGIRGTLGKLQAISWARARKIPFLGVCLGMQLAVIEFARNCLNLKDADSTEFEPNARVPVVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRYEVNPSLINQLEQNDLSFVGQDVDGERMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLLRGCKLSSSDRYSDASDDSFSEPRIAELDIS", "length": 586, "header": "tr|A0A4X1UU82-1|A0A4X1UU82_PIG Isoform 1 of CTP synthase OS=Sus scrofa OX=9823 GN=CTPS2 PE=1 SV=1 CANONICAL=A0A4X1UU82-1" }, "locus": { "chromosome": "X", "start_pos": 13167425, "end_pos": 13051968, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070559.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070559.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060857.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060857.1" } ] } }, { "isoform_ac": "F1SQS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82/entry#F1SQS3-1", "sequence": { "sequence": "MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHVVPHITDAVQEWVMNQATVPVDGHKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVKPEQVICIHDVSSTYRVPVLLEEQGIVKYFKERLDLPIGDSASNLLFKWRNMADRYERLQKTCSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEQTTETEDPVKFHEAWQKLCKADGVLVPGGFGIRGTLGKLQAISWARARKIPFLGVCLGMQLAVIEFARNCLNLKDADSTEFEPNARVPVVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRYEVNPSLINQLEQNDLSFVGQDVDGERMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLLRGCKLSSSDRYSDASDDSFSEPRIAELDIS", "length": 529, "header": "tr|F1SQS3-1|F1SQS3_PIG Computationally mapped isoform of CTP synthase OS=Sus scrofa OX=9823 GN=CTPS2 PE=1 SV=5 CANONICAL=A0A4X1UU82-1" }, "locus": { "chromosome": "X", "start_pos": 13167425, "end_pos": 13051968, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013285.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013285.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012929.5", "url": "https://www.ensembl.org/id/ENSSSCP00000012929.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A480TY64", "url": "https://www.uniprot.org/uniprotkb/A0A480TY64" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520595", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520595", "resource": "KEGG Pathway" }, { "id": "R-SSC-499943", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-499943", "resource": "Reactome", "description": "Interconversion of nucleotide di- and triphosphates" } ], "orthologs": [ { "uniprot_canonical_ac": "F4I6G9-1", "protein_name": "CTP synthase", "gene_name": "CTPS1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKYVLVTGGVVSGLGKGVTASSIGVLLKACGLRVTSIKIDPYLNTDAGTMSPFEHGEVFVLDDGGEVDLDLGNYERFLDIKLTRDNNITTGKIYQHVIAKERKGDYLGKTVQVVPHVTDAIQDWIERVAVIPVDGEEDPADVCVIELGGTIGDIESAPFIEALGQFSYRVGPGNFCLVHVSLVPVLNVVGEQKTKPTQHSVKGLRGLGLTPDILACRSTKPLEDNVKEKLAQFCHVPLEYIFTLYDVPNIWRIPLLLKDQKAHLAISKVLNLASILNEPSLGEWTSRAELCDNLHVPVRIAVVGKYTGLSDAYLSVLKALLHASVACRKKLVVDWVPACDLEKETEKENPDAYKAAWKLLKGVDGILVPGGFGDRGVEGKILAAKYARENKIPFLGICLGMQIAVIEFARSVLSLQDANSTEFNPETKHPCIIFMPEGSKTHMGGTMRLGSRKSIFNVKDSKSAKLYENKSFVDERHRHRYEVNPDMVERLEKAGLSFAAKDETGKRMEIIELPNHPFFIGAQFHPEFKSRPGKASPLFLGLIAASCGELDTVLNPASAHQHSISNGPTNIFINGTSKKSPNGLADVRYNNGYCNGLYTR", "length": 600 }, "evidence": [ { "id": "A0A4X1UU82", "url": "https://omabrowser.org/oma/group/A0A4X1UU82/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38627-1", "protein_name": "CTP synthase 2", "gene_name": "URA8", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKYVVVSGGVISGIGKGVLASSTGMLLKTLGLKVTSIKIDPYMNIDAGTMSPLEHGECFVLDDGGETDLDLGNYERYLGITLSRDHNITTGKIYSHVISRERRGDYLGKTVQIVPHLTNAIQDWIQRVSKIPVDDTGLEPDVCIIELGGTVGDIESAPFVEALRQFQFEVGRENFALIHVSLVPVIHGEQKTKPTQAAIKDLRSLGLIPDMIACRCSEELNRSTIDKIAMFCHVGPEQVVNVHDVNSTYHVPLLLLKQHMIDYLHSRLKLGEVPLTLEDKERGSQLLTNWENMTKNLDDSDDVVKIALVGKYTNLKDSYLSVTKSLEHASMKCRRQLEILWVEASNLEPETQEVDKNKFHDSWNKLSSADGILVPGGFGTRGIEGMILAAKWARESGVPFLGVCLGLQVAAIEFARNVIGRPNSSSTEFLDETLLAPEDQVVIYMPEIDKEHMGGTMRLGLRPTIFQPNSEWSNIRKLYGEVNEVHERHRHRYEINPKIVNDMESRGFIFVGKDETGQRCEIFELKGHPYYVGTQYHPEYTSKVLEPSRPFWGLVAAASGTLGEVIKDINLSEGNENE", "length": 578 }, "evidence": [ { "id": "A0A4X1UU82", "url": "https://omabrowser.org/oma/group/A0A4X1UU82/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P70303-1", "protein_name": "CTP synthase 2", "gene_name": "Ctps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAIQEWVMNQAKVSVDGNKEDPQICVIELGGTIGDIEGMAFVEAFRQFQFKAKKENFYNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSIYRVPLLLEEQGVVKYFQERLGLPINDCSSNLLFKWKAMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEPVTKAEDPVKFHEAWQKLCLADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGICLGMQLAVIEFARNCLNLKDANSTEFEPNTPVPLVIDMPEHNPGDLGGTMRLGLRRTVFTTENSILKKLYGDVPYIEERHRHRYEVNPNLINQFENKDLCFVGEDVDGKRMEIVELTSHPYFIGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAHLQQMNKLPYSDGYSDASDDSFPEAKLAELDLN", "length": 586 }, "evidence": [ { "id": "A0A4X1UU82", "url": "https://omabrowser.org/oma/group/A0A4X1UU82/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1RMS2-1", "protein_name": "CTP synthase 2", "gene_name": "CTPS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAMVPVDGHKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSTYRVPVLLEEQGIIKYFKERLDLPIGDSASSLLSKWRNMADRYERLQKTCSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEQTTEVEDPVKFHEAWQKLCKADGVLVPGGFGIRGTLGKLQAISWARSRKIPFLGVCLGMQLAVIEFARNCLNLKDADSTEFEPNARVPVVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRYEVNPSLISQLEQKDLSFVGQDVDGERMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLLQGCKLSSSDRYSDASDDSFSEPRLAELEIS", "length": 586 }, "evidence": [ { "id": "A0A4X1UU82", "url": "https://omabrowser.org/oma/group/A0A4X1UU82/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5F3Z1-1", "protein_name": "CTP synthase 2", "gene_name": "CTPS2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERHGDYLGKTVQVVPHITDAVQEWVMNQAKVPVDDDRKEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQPNATGEQKTKPTQNSVRALRGLGLSPDLIVCRSAKPIEMAVKEKISMFCHVEPEQVIFIHDVSSTYRVPILLEEQGIIKYFKQRLNLPIDDQPSDLLMKWKKMADRYERLLKVCSIALVGKYTKLSDCYASVFKALEHSALAINHKLDLMYIDSTELERSTEVENSVKYHQAWHKLCKADGILVPGGFGIRGTEGKLQAISWARTKKKPFLGVCLGMQLAVVEFARNCLNWKDANSTEFDPDTKSPVVIDMPEHNPGDMGGTMRLGKRRTVFKTQNSILRKLYGDEMFVEERHRHRYEVNPELTHCFEEKGLKFVGHDTEGNRMEMIELENHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGTLNAYLQRGCKLSPSESYSDLSDDSSPEKEFPKSETS", "length": 586 }, "evidence": [ { "id": "A0A4X1UU82", "url": "https://omabrowser.org/oma/group/A0A4X1UU82/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5U2N0-1", "protein_name": "CTP synthase 2", "gene_name": "Ctps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAIQDWVMNQAKVSVDGNKEDPQICVIELGGTIGDIEGMAFVEAFRQFQFKAKRENFYNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSIYRVPLLLEEQGVVKYFQERLDLPINDCSNNLLFKWKTMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEPVTKAEDPVKFHEAWQKLCLADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGICLGMQLAVIEFARNCLNLKDANSTEFDPNTPVPLVIDMPEHNPGDLGGTMRLGLRRTVFTTENSILKKLYGDVPYIEERHRHRYEVNPNLINQFENKDLCFVGEDVDGKRMEIIELTGHPYFIGVQFHPEFSSRPMKPSPPYLGLLLAATGTLNTHLQQMSKLSYSDIYSDASDDSFSEAKFAELDIN", "length": 586 }, "evidence": [ { "id": "A0A4X1UU82", "url": "https://omabrowser.org/oma/group/A0A4X1UU82/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NRF8-1", "protein_name": "CTP synthase 2", "gene_name": "CTPS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAKVPVDGNKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQLSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSTYRVPVLLEEQSIVKYFKERLHLPIGDSASNLLFKWRNMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEKITETEDPVKFHEAWQKLCKADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGVCLGMQLAVIEFARNCLNLKDADSTEFRPNAPVPLVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRFEVNPNLIKQFEQNDLSFVGQDVDGDRMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLQQGCKLSSSDRYSDASDDSFSEPRIAELEIS", "length": 586 }, "evidence": [ { "id": "A0A4X1UU82", "url": "https://omabrowser.org/oma/group/A0A4X1UU82/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" } ], "pmid": "" }, { "name": "CTP synthase activity", "id": "GO:0003883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003883", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" } ], "pmid": "" }, { "name": "cytoophidium", "id": "GO:0097268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097268", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "'de novo' CTP biosynthetic process", "id": "GO:0044210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044210", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" } ], "pmid": "" }, { "name": "CTP biosynthetic process", "id": "GO:0006241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006241", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" } ], "pmid": "" }, { "name": "pyrimidine nucleobase biosynthetic process", "id": "GO:0019856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019856", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UU82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "26426", "name": "", "equation": "UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "26426", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/26426" } ] }, { "id": "R-SSC-504054", "name": "Amination of uridine 5'-triphosphate (UTP) to form cytidine 5'-triphosphate (CTPS2)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29494" ], "output_participant_list": [ "R-ALL-110614" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-504054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-504054" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-110614", "participant_name": "CTP [cytosol]", "crossref": [ { "id": "ZINC000003861746", "database": "ZINC", "url": "" }, { "id": "37563", "database": "ChEBI", "url": "" }, { "id": "C00063", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-29494", "participant_name": "UTP [cytosol]", "crossref": [ { "id": "46398", "database": "ChEBI", "url": "" }, { "id": "ZINC000003861755", "database": "ZINC", "url": "" }, { "id": "C00075", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UU82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" }, { "id": "PF06418", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06418" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CTP synthase N-terminal", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 272, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1UU82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UU82" }, { "id": "PF00117", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00117" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glutamine amidotransferase", "eco_id": "ECO_0000259", "start_pos": 310, "end_pos": 539, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UWE5-1", "uniprot_ac": "A0A4X1UWE5", "uniprot_id": "A0A4X1UWE5_PIG", "mass": { "chemical_mass": 68253.0, "monoisotopic_mass": 68253.0 }, "refseq": {}, "gene_names": [ { "name": "PPEF1", "type": "recommended", "evidence": [ { "id": "A0A4X1UWE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein phosphatase", "type": "recommended", "evidence": [ { "id": "A0A4X1UWE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "A0A4X1UWE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PPEF1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5", "locus": { "chromosome": "X", "start_pos": 15251228, "end_pos": 15138350, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000030274", "url": "https://www.ensembl.org/id/ENSSSCG00000030274" } ] } } ], "crossref": [ { "id": "A0A4X1UWE5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UWE5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000030274", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000030274", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07420", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07420", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100623891", "url": "https://www.ncbi.nlm.nih.gov/gene/100623891", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SHDNEIN", "url": "https://omabrowser.org/oma/group/SHDNEIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "I3LR47", "url": "https://www.orthodb.org/?gene=I3LR47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45668", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45668", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45668:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45668:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2514859", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2514859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UWE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UWE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0X7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8D0X7Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0X7Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0X7Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LR47", "url": "https://www.uniprot.org/uniprotkb/I3LR47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LR47-1", "url": "https://www.uniprot.org/uniprotkb/I3LR47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GM53", "url": "https://www.uniprot.org/uniprotkb/K7GM53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GM53-1", "url": "https://www.uniprot.org/uniprotkb/K7GM53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCGTSSSAKDRKSENALKAALVIQNWYRGYSARLKARQRYALTIFQSIEYADEQGQLQLSNFFSFMLENYTHVHEKDRELVTRLFSGSIQDKKDRQDYLGLIDVPDSYSGPRLQFPLTFTDIDLLIEAFKQQQILHAYYVLEVLFETKKVLQQMPNFTHTKTSPSKEITICGDLHGKLDDLFLIFYKNGLPSVSNPYVFNGDFVDRGKNSMEILMILFVSFLVYPNDLHLNRGNHEDFMMNMRYGFTKEILHKYKLHGKKILQILEDVYTWLPIGTIIDNEVLVIHGGISESTDLNLLHRIERNKMKSVLMPPIPLDGDRVSEKKNKVGPTITAQGIRADGSASEQLTKHEWEQVITVFSASNYYEEGSNRGAYIRMSSGTTPRFFQYQVTRATCLRPLYQRVNAIESSAIRMLKERMISRKTDLIRAFQLQDRNKSGKLSMGQWAFSMENVLGLNLPWRSLSSHLVTTDKDGNIDYMSTFQDLHIQKPVKEVQSSLIETVYRYRSDLQIIFNIIDSDHSGLISMEEFRSMWKLFKSHYSVHIDDSQFDELAERMDLNKDGSIDFNEFLKAFYVVHKFDKLSKSDTKLA", "length": 590, "header": "tr|A0A4X1UWE5-1|A0A4X1UWE5_PIG Isoform 1 of Serine/threonine-protein phosphatase OS=Sus scrofa OX=9823 GN=PPEF1 PE=3 SV=1 CANONICAL=A0A4X1UWE5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UWE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5/entry#A0A4X1UWE5-1", "sequence": { "sequence": "MGCGTSSSAKDRKSENALKAALVIQNWYRGYSARLKARQRYALTIFQSIEYADEQGQLQLSNFFSFMLENYTHVHEKDRELVTRLFSGSIQDKKDRQDYLGLIDVPDSYSGPRLQFPLTFTDIDLLIEAFKQQQILHAYYVLEVLFETKKVLQQMPNFTHTKTSPSKEITICGDLHGKLDDLFLIFYKNGLPSVSNPYVFNGDFVDRGKNSMEILMILFVSFLVYPNDLHLNRGNHEDFMMNMRYGFTKEILHKYKLHGKKILQILEDVYTWLPIGTIIDNEVLVIHGGISESTDLNLLHRIERNKMKSVLMPPIPLDGDRVSEKKNKVGPTITAQGIRADGSASEQLTKHEWEQVITVFSASNYYEEGSNRGAYIRMSSGTTPRFFQYQVTRATCLRPLYQRVNAIESSAIRMLKERMISRKTDLIRAFQLQDRNKSGKLSMGQWAFSMENVLGLNLPWRSLSSHLVTTDKDGNIDYMSTFQDLHIQKPVKEVQSSLIETVYRYRSDLQIIFNIIDSDHSGLISMEEFRSMWKLFKSHYSVHIDDSQFDELAERMDLNKDGSIDFNEFLKAFYVVHKFDKLSKSDTKLA", "length": 590, "header": "tr|A0A4X1UWE5-1|A0A4X1UWE5_PIG Isoform 1 of Serine/threonine-protein phosphatase OS=Sus scrofa OX=9823 GN=PPEF1 PE=3 SV=1 CANONICAL=A0A4X1UWE5-1" }, "locus": { "chromosome": "X", "start_pos": 15250814, "end_pos": 15146530, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083214.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083214.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070545.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070545.1" } ] } }, { "isoform_ac": "A0A8D0X7Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5/entry#A0A8D0X7Z0-1", "sequence": { "sequence": "MLSNFFSFMLENYTHVHEKDRELVTRLFSGSIQDKKDRQDYLGLIDVPDSYSGPRLQFPLTFTDIDLLIEAFKQQQILHAYYVLEVLFETKKVLQQMPNFTHTKTSPSKEITICGDLHGKLDDLFLIFYKNGLPSVSNPYVFNGDFVDRGKNSMEILMILFVSFLVYPNDLHLNRGNHEDFMMNMRYGFTKEILHKYKLHGKKILQILEDVYTWLPIGTIIDNEVLVIHGGISESTDLNLLHRIERNKMKSVLMPPIPLDGDRVSEKKNKVGPTITAQGIRADGSASEQLTKHEWEQVVDILWSDPRGKRGCYPNTSRGGGCYFGPDITSKILNKYQLKMLVRSHECKPEGYEICHDGKVITVFSASNYYEEGSNRGAYIRMSSGTTPRFFQYQVTRATCLRPLYQRVNAIESSAIRMLKERMISRKTDLIRAFQLQDRNKSGKLSMGQWAFSMENVLGLNLPWRSLSSHLVTTDKDGNIDYMSTFQDLHIQKPVKEVQSSLIETVYRYRSDLQIIFNIIDSDHSGLISMEEFRSMWKLFKSHYSVHIDDSQFDELAERMDLNKDGSIDFNEFLKAFYVVHKFDKLSKSDTKLA", "length": 594, "header": "tr|A0A8D0X7Z0-1|A0A4X1UWE5_PIG Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Sus scrofa OX=9823 GN=PPEF1 PE=3 SV=1 CANONICAL=A0A4X1UWE5-1" }, "locus": { "chromosome": "X", "start_pos": 15250814, "end_pos": 15146576, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000034554.4", "url": "https://www.ensembl.org/id/ENSSSCT00000034554.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056036.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056036.2" } ] } }, { "isoform_ac": "I3LR47-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5/entry#I3LR47-1", "sequence": { "sequence": "MGCGTSSSAKDRKSENALKAALVIQNWYRGYSARLKARQRYALTIFQSIEYADEQGQLQLSNFFSFMLENYTHVHEKDRELVTRLFSGSIQDKKDRQDYLGLIDVPDSYSGPRLQFPLTFTDIDLLIEAFKQQQILHAYYVLEVLFETKKVLQQMPNFTHTKTSPSKEITICGDLHGKLDDLFLIFYKNGLPSVSNPYVFNGDFVDRGKNSMEILMILFVSFLVYPNDLHLNRGNHEDFMMNMRYGFTKEILHKYKLHGKKILQILEDVYTWLPIGTIIDNEVLVIHGGISESTDLNLLHRIERNKMKSVLMPPIPLDGDRVSEKKNKVGPTITAQGIRADGSASEQLTKHEWEQVVDILWSDPRGKRGCYPNTSRGGGCYFGPDITSKILNKYQLKMLVRSHECKPEGYEICHDGKVITVFSASNYYEEGSNRGAYIRMSSGTTPRFFQYQVTRATCLRPLYQRVNAIESSAIRMLKERMISRKTDLIRAFQLQDRNKSGKLSMGQWAFSMENVLGLNLPWRSLSSHLVTTDKDGNIDYMSTFQDLHIQKPVKEVQSSLIETVYRYRSDLQIIFNIIDSDHSGLISMEEFRSMWKLFKSHYSVHIDDSQFDELAERMDLNKDGSIDFNEFLKAFYVVHKFDKLSKSDTKLA", "length": 652, "header": "tr|I3LR47-1|A0A4X1UWE5_PIG Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Sus scrofa OX=9823 GN=PPEF1 PE=3 SV=2 CANONICAL=A0A4X1UWE5-1" }, "locus": { "chromosome": "X", "start_pos": 15250814, "end_pos": 15146530, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031758.4", "url": "https://www.ensembl.org/id/ENSSSCT00000031758.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026579.2", "url": "https://www.ensembl.org/id/ENSSSCP00000026579.2" } ] } }, { "isoform_ac": "K7GM53-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5/entry#K7GM53-1", "sequence": { "sequence": "MGCGTSSSAKDRKSENALKAALVIQNWYRGYSARLKARQRYALTIFQSIEYADEQGQLQLSNFFSFMLENYTHVHEKDRELVTRLFSGSIQDKKDRQDYLGLIDVPDSYSGPRLQFPLTFTDIDLLIEAFKQQQILHAYYVLEVLFETKKVLQQMPNFTHTKTSPSKEITICGDLHGKLDDLFLIFYKNGLPSVSNPYVFNGDFVDRGKNSMEILMILFVSFLVYPNDLHLNRGNHEDFMMNMRYGFTKEILHKYKMKSVLMPPIPLDGDRVSEKKNKVGPTITAQGIRADGSASEQLTKHEWEQVVDILWSDPRGKRGCYPNTSRGGGCYFGPDITSKILNKYQLKMLVRSHECKPEGYEICHDGKVITVFSASNYYEEGSNRGAYIRMSSGTTPRFFQYQVTRATCLRPLYQRVNAIESSAIRMLKERMISRKTDLIRAFQLQDRNKSGKLSMGQWAFSMENVLGLNLPWRSLSSHLVTTDKDGNIDYMSTFQDLHIQKPVKEVQSSLIETVYRYRSDLQIIFNIIDSDHSGLISMEEFRSMWKLFKSHYSVHIDDSQFDELAERMDLNKDGSIDFNEFLKAFYVVHKFDKLSKSDTKLA", "length": 602, "header": "tr|K7GM53-1|A0A4X1UWE5_PIG Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Sus scrofa OX=9823 GN=PPEF1 PE=3 SV=2 CANONICAL=A0A4X1UWE5-1" }, "locus": { "chromosome": "X", "start_pos": 15250814, "end_pos": 15146530, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035020.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035020.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028941.2", "url": "https://www.ensembl.org/id/ENSSSCP00000028941.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 332, "start_aa": "Thr", "end_pos": 332, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr332", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0X7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8D0X7Z0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2514859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2514859", "resource": "Reactome", "description": "Inactivation, recovery and regulation of the phototransduction cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9QHP8-1", "protein_name": "Serine/threonine-protein phosphatase with EF-hands", "gene_name": "ppef1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCGTSIAIENQTRPSETDGSIKQSNPALTIKAAILIQRWYRRYVAHLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFTFMLDNFTQINGNGPDLISHLLDSVVDPLTEEVRQLKYEQIMVPESYSGPRLSFPLSVTDTNALLSAFKEEQTLHGKYVLQLLYETKKFLKQMPNVIYLSTSYAKEITICGDLHGRLDDLLLIFYKNGLPSAENPYIFNGDFVDRGKKSTEIIIILFAFVLLYPDHMHLNRGNHEDHIMNLRYGFTREVMQKYKTHGREILQLLQDVFSLLPVATVIDNKVLIVHGGISDKTDLDFLSTVERHKVKSALRLPKRSTDHLTVRSCSRSSSRNRGRNSRSSSRHSSRSRRKKLSKQGSRSSSSSSSSSSSSSMCSPRVSAKNTPRRPPPSPTDMLQVPFLDSFVSLEPPELPREELEWQQVVDILWSDPKHQNGCSPNSFRGGGCYFGPDVTQTLLQKHGLCLLIRSHECKQEGYELCHNGQVITIFSASNYYEEGSNRGAYVKLGPELVPRFFQYQVSRSTRKLTLHQRVRVAEGSALRALKEKLYAHRSELMAAFQQYDINNTGRISTSEWAQVVESVLRLDLPWRTLRPRLARLGTDGNVEYESCFEDISPGEPIPPVTPNLAETLYRYRTDLEIIFNIIDKDHSGQISIEEFRQTWKLFSSHLGVAVNDQTIDDMARSIDFNKDGSIDFTEFLEAFRVVHKLDVKEQQQG", "length": 729 }, "evidence": [ { "id": "A0A4X1UWE5", "url": "https://omabrowser.org/oma/group/A0A4X1UWE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BTX9-1", "protein_name": "Serine/threonine-protein phosphatase", "gene_name": "PPEF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MECTISTMGCNASAHYSKHKYNETAIKATVLIQRWYRCKRAQLEVRRRYSLTIFQSIEYADEQEQTQLSNFFTFMLEHCVHRGEVARTSTGSDVSPGTDSYVIKYEKIDVPDSYRGPRLSFPLDISHAKTLLNALKDRQLLHARYVLQLLCETRRVLKEKPNITHVSVSYFKEITICGDLHGNLDDLLLVFHKNGLPSENNPYVFNGDFVDRGKNSMEILIILFVFLLIYPNDFHLNRGNHEDYILNMKYGFAKEVLKKYKDHGKTILHHLQDIFSWLPLATIVNNKVLIVHGGISDTTDLDSLNLLERNKLKTLMKTRKLETDKKNQEEHSELTEKERKQVLDILWSDPNKQHGCTPNQRRGGGCYFGPDTTDQLLKRYNLKMLIRSHEFKPDGYDLTHNGKVITIFSASNYYEAGSNRGAYIRMNPDLVPHFIQYQVCACTDKKKNWERVKTIEQSALQNLQERIFVHKRKLMDTFAKCDCKNTGRISISDWAAVMESVLQLKLPWRMLRSRLVKTDPDGKVDYMSCFCYMDTARPMHQVQPTLVETLCKYRRDLQMIFNVLDEDRSGLISPNEFRKMWKIFSSYLGIHSHDEAVDKLAQSIDFNKDGNIDFSEFLEAFHVVHQLENKAA", "length": 632 }, "evidence": [ { "id": "A0A4X1UWE5", "url": "https://omabrowser.org/oma/group/A0A4X1UWE5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MBQ1-1", "protein_name": "Serine/threonine-protein phosphatase with EF-hands", "gene_name": "PPEF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNTPNLEDMGCGTSSATKDKKSEKALKAALVIQNWYRGYSARLKTRQRYALTIFQSIEYADEQGQLQLSNFFSFMLENYTNVPEKEPGLVTRLFGSSIQDKDRQDYLGLIEIPDSYCGPRLQFPLTFTDIDLLIEAFKQQQILHAYYVLEVLFETKKVLQQMPNFTHTNTSPSKEITICGDLHGKLDDLFLIFYKNGLPSVTNPYVFNGDFVDRGKNSMEILMILFVSFLVYPNDLHLNRGNHEDFMMNMRYGFTKEILHKYKLHGKKILQILEEVYTWLPIGTIIDNEVLVIHGGISESTDLNLLHRIERNKMRSVLMPPIPMDGDRAEKKNKLGTATVALGIRTSGSFSEQLTKQEWEQVIDILWSDPRGKRGCYPNTNRGGGCYFGPDITSKILNKYQLKMLVRSHECKPEGYEICHDGKVITVFSASNYYEEGSNRGAYIRMSSGTTPRFFQYQITKATCFRPLYQRVNAIESSAIRMLKERMISRKTDLIRAFQLQDRNKSGKLSMGQWAFSMENVLGLNLPWRSLSSHLVTTDKDGNIDYMSGFQDVHIQKPVKEVQSSLIETVYRYRSDLQIIFNIIDSDHSGLISMEEFRSMWRLFKSHYSVHIDDSQFDELAERMDLNKDGSIDFNEFLKAFYVVHKFDQLNKSDTKLA", "length": 658 }, "evidence": [ { "id": "A0A4X1UWE5", "url": "https://omabrowser.org/oma/group/A0A4X1UWE5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O14829-1", "protein_name": "Serine/threonine-protein phosphatase with EF-hands 1", "gene_name": "PPEF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLSTFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG", "length": 653 }, "evidence": [ { "id": "A0A4X1UWE5", "url": "https://omabrowser.org/oma/group/A0A4X1UWE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35655-1", "protein_name": "Serine/threonine-protein phosphatase with EF-hands 1", "gene_name": "Ppef1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCGTSSKKGNKSKKVIKAALVIQNWYRRYRARLRVRQHYALAIFQSIEYSDEQGQMQLSSFFSFMLENYTKTNNEDSALVTRIFDNTRRESQIKDRDDFLGLIEVPDSYDGPRLQFPLTFTDIHILLQAFKQQQILHAHYVLEVLFEARKVLKQMPNFSHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPSENNPYVFNGDFVDRGNNSMEILMILLVCFLVYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGRKILQVLEEVYTWLPIGTIIDNEILVIHGGISESTDLNTLHQLQRNKMKSVLMPPVLGNQETGEKRNKSASNYVEPRKVEPDKTPSEDLTKQEWEQIVDILWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLSKNQLKMLIRSHECKPDGYEVSHDGKVITVFSASNYYEEGSNRGAYIRLSYGTMPQFFQYQVTSTSCLNPLHQRMNAMESSAFKILKEKMISRKTDLINAFELRDHSRSGRISLAEWAFSMENILGLNLPWRSLSSHLVTIDSSGSVDYMSSFDDIRIEKPTKDMKSNLTETMYRYRSDLKIIFNIIDSDQSGLISMDEFRTMWKLFNAHYKAHIDDSQIDELASIVDFNKDGNIDFNEFLKAFYVVHKYDKPGTSLA", "length": 650 }, "evidence": [ { "id": "A0A4X1UWE5", "url": "https://omabrowser.org/oma/group/A0A4X1UWE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3SWT6-1", "protein_name": "Serine/threonine-protein phosphatase with EF-hands 1", "gene_name": "Ppef1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCGSSSKKGKKSEKVVRAALIIQNWYRRYRARLSARQHYALAIFQSIEYADEQGQMQLSSFFSFMLENYTNTHKEDSALVSRLFENTRLESKDREEYVGLIDVPDSYDGPRLQFPLTFTDINLLLQAFKQQQTLHAHYVLEVLFEARKILKQMPNFTRIQTFPAKEITICGDLHGKLDDLMLIFYKNGLPSEKNPYVFNGDFVDRGNNSMEILMILLVSFLVYPTDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGKKILQVLEELYTWLPIGTIIDNEILVIHGGISESTDLNILQQLQRNKMKSVLMPPMSTNQECNIKKNKAGPSEQSASEQLTKLEWEQIIDLLWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLNKNQLKMVIRSHECKPDGYEICHDGKVITVFSASNYYEEGSNRGAYIRLSYGTSPQFFQYQVTSTSCLNPLYQRVNAMEFSAFRILKERMIARKTDLINAFELRDHSRTGKISLAQWAFSMESILGLNLPWRSLSSHLVSTDSSGSVDYMSSFDDIHIEKPMKDMKSDLIETMYRYRSDLKIIFNIIDTDQSGLISMDEFRTMWKLFNAHYKVHIDDSQIDELASTMDSNKDGNIDFNEFLRAFYVVHKYETPESPLNK", "length": 640 }, "evidence": [ { "id": "A0A4X1UWE5", "url": "https://omabrowser.org/oma/group/A0A4X1UWE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of stimulus involved in sensory perception", "id": "GO:0050906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050906", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] }, { "id": "R-SSC-74948", "name": "PP2A dephosphorylates p-RHO to RHO", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, photoreceptor disc membrane", "input_participant_list": [ "R-SSC-2581504" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-74948", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-74948" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-2581504", "participant_name": "phospho-p-S334,338,343-RHO [photoreceptor disc membrane]", "crossref": [ { "id": "O18766", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000011590", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000012353", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000012686", "database": "ENSEMBL", "url": "" }, { "id": "NP_999386.1", "database": "RefSeq", "url": "" }, { "id": "92283", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UWE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWE5" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 421, "end_pos": 456, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 332 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VF75-1", "uniprot_ac": "A0A4X1VF75", "uniprot_id": "A0A4X1VF75_PIG", "mass": { "chemical_mass": 23870.0, "monoisotopic_mass": 23870.0 }, "refseq": { "ac": "XP_020924844", "name": "THO complex subunit 7 homolog isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924844" }, "gene_names": [ { "name": "THOC7", "type": "recommended", "evidence": [ { "id": "A0A4X1VF75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75" } ] }, { "name": "THOC7", "type": "synonym", "evidence": [ { "id": "XP_020924844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924844" } ] } ], "protein_names": [ { "name": "THO complex subunit 7 homolog isoform X3", "type": "synonym", "evidence": [ { "id": "XP_020924844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924844" } ] }, { "name": "THO complex subunit 7", "type": "synonym", "evidence": [ { "id": "A0A4X1VF75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. Required for efficient export of polyadenylated RNA. Plays a key structural role in the oligomerization of the THO-DDX39B complex. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NXF1 pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BD32", "url": "https://www.uniprot.org/uniprotkb/A0A287BD32#function" }, { "database": "UniProtKB", "id": "ARBA00046174", "url": "https://www.uniprot.org/uniprotkb/ARBA00046174#function" }, { "database": "UniProtKB", "id": "A0A5G2QLS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLS4#function" }, { "database": "UniProtKB", "id": "A0A8D1QZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1QZJ1#function" }, { "database": "UniProtKB", "id": "A0A4X1VF75", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75#function" }, { "database": "UniProtKB", "id": "A0A5G2RDF2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDF2#function" }, { "database": "UniProtKB", "id": "A0A8W4FFQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFQ7#function" }, { "database": "UniProtKB", "id": "F1SGF4", "url": "https://www.uniprot.org/uniprotkb/F1SGF4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VF75", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "THOC7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75", "locus": { "chromosome": "13", "start_pos": 45334029, "end_pos": 45356060, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011491", "url": "https://www.ensembl.org/id/ENSSSCG00000011491" } ] } } ], "crossref": [ { "id": "A0A4X1VF75", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1VF75", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011491", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011491", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100519334", "url": "https://www.ncbi.nlm.nih.gov/gene/100519334", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519334", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519334", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WANSKND", "url": "https://omabrowser.org/oma/group/WANSKND/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287BD32", "url": "https://www.orthodb.org/?gene=A0A287BD32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1SGF4", "url": "https://www.orthodb.org/?gene=F1SGF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23405", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23405", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23405:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23405:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72187", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72187", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020924844", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924844", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BD32", "url": "https://www.uniprot.org/uniprotkb/A0A287BD32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BD32-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BD32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VF75", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VF75-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLS4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDF2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1QZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1QZJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1QZJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1QZJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SGF4", "url": "https://www.uniprot.org/uniprotkb/F1SGF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SGF4-1", "url": "https://www.uniprot.org/uniprotkb/F1SGF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLYEYEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEVEEAQETSMETDPKP", "length": 203, "header": "tr|A0A4X1VF75-1|A0A4X1VF75_PIG Isoform 1 of THO complex subunit 7 OS=Sus scrofa OX=9823 GN=THOC7 PE=1 SV=1 CANONICAL=A0A4X1VF75-1" }, "isoforms": [ { "isoform_ac": "A0A287BD32-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75/entry#A0A287BD32-1", "sequence": { "sequence": "MVKKNNTLQEIEEEMHHVASENLPFHPPLLTPLLRDEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEVEEAQETSMETDPKP", "length": 233, "header": "tr|A0A287BD32-1|A0A4X1VF75_PIG Computationally mapped isoform of THO complex subunit 7 OS=Sus scrofa OX=9823 GN=THOC7 PE=1 SV=1 CANONICAL=A0A4X1VF75-1" }, "locus": { "chromosome": "13", "start_pos": 45351334, "end_pos": 45336052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043715.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043715.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054002.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054002.1" } ] } }, { "isoform_ac": "A0A4X1VF75-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75/entry#A0A4X1VF75-1", "sequence": { "sequence": "MSLYEYEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEVEEAQETSMETDPKP", "length": 203, "header": "tr|A0A4X1VF75-1|A0A4X1VF75_PIG Isoform 1 of THO complex subunit 7 OS=Sus scrofa OX=9823 GN=THOC7 PE=1 SV=1 CANONICAL=A0A4X1VF75-1" }, "locus": { "chromosome": "13", "start_pos": 45353052, "end_pos": 45336052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077589.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077589.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069097.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069097.1" } ] } }, { "isoform_ac": "A0A5G2QLS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75/entry#A0A5G2QLS4-1", "sequence": { "sequence": "FTFQKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEVEEAQETSMETDPKP", "length": 197, "header": "tr|A0A5G2QLS4-1|A0A5G2QLS4_PIG Computationally mapped isoform of THO complex subunit 7 OS=Sus scrofa OX=9823 GN=THOC7 PE=1 SV=2 CANONICAL=A0A4X1VF75-1" }, "locus": { "chromosome": "13", "start_pos": 45343574, "end_pos": 45336052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081778.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081778.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064995.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064995.2" } ] } }, { "isoform_ac": "A0A5G2RDF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75/entry#A0A5G2RDF2-1", "sequence": { "sequence": "FFPPDEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEVEEAQETSMETDPKP", "length": 202, "header": "tr|A0A5G2RDF2-1|A0A4X1VF75_PIG Computationally mapped isoform of THO complex subunit 7 OS=Sus scrofa OX=9823 GN=THOC7 PE=1 SV=2 CANONICAL=A0A4X1VF75-1" }, "locus": { "chromosome": "13", "start_pos": 45343470, "end_pos": 45336052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068835.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068835.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072403.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072403.2" } ] } }, { "isoform_ac": "A0A8D1QZJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75/entry#A0A8D1QZJ1-1", "sequence": { "sequence": "FTAVTPRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEVEEAQETSMETDPKP", "length": 198, "header": "tr|A0A8D1QZJ1-1|A0A4X1VF75_PIG Computationally mapped isoform of THO complex subunit 7 OS=Sus scrofa OX=9823 GN=THOC7 PE=1 SV=1 CANONICAL=A0A4X1VF75-1" }, "locus": { "chromosome": "13", "start_pos": 45343771, "end_pos": 45336052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097452.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097452.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079960.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079960.1" } ] } }, { "isoform_ac": "A0A8W4FFQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75/entry#A0A8W4FFQ7-1", "sequence": { "sequence": "CSFYQYLTLVRYEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEVEEAQETSMETDPKP", "length": 209, "header": "tr|A0A8W4FFQ7-1|A0A4X1VF75_PIG Computationally mapped isoform of THO complex subunit 7 OS=Sus scrofa OX=9823 GN=THOC7 PE=1 SV=1 CANONICAL=A0A4X1VF75-1" }, "locus": { "chromosome": "13", "start_pos": 45344166, "end_pos": 45336052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095534.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095534.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078152.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078152.1" } ] } }, { "isoform_ac": "F1SGF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75/entry#F1SGF4-1", "sequence": { "sequence": "MGAVTDDEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEVEEAQETSMETDPKP", "length": 204, "header": "tr|F1SGF4-1|F1SGF4_PIG Computationally mapped isoform of THO complex subunit 7 OS=Sus scrofa OX=9823 GN=THOC7 PE=1 SV=2 CANONICAL=A0A4X1VF75-1" }, "locus": { "chromosome": "13", "start_pos": 45356037, "end_pos": 45336052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012574.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012574.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012245.2", "url": "https://www.ensembl.org/id/ENSSSCP00000012245.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1QZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1QZJ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519334", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519334", "resource": "KEGG Pathway" }, { "id": "R-SSC-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-SSC-72187", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72187", "resource": "Reactome", "description": "mRNA 3'-end processing" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ABD9-1", "protein_name": "THO complex subunit 7", "gene_name": "Thoc7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQCAEGAAWGASPALLSRAHRQRGGPLGALELGGRWSEDTEVGTASKRNRGVWRAGREVYLGGLQDEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDDKLSEVEEAQESAMEADPKP", "length": 263 }, "evidence": [ { "id": "A0A4X1VF75", "url": "https://omabrowser.org/oma/group/A0A4X1VF75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N915-1", "protein_name": "THO complex 7", "gene_name": "THOC7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGAVTDDEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKDIENSIAAAHEKISECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKQLEALGKELQHLSHIKENVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEAEESQETQMEAETKQ", "length": 204 }, "evidence": [ { "id": "A0A4X1VF75", "url": "https://omabrowser.org/oma/group/A0A4X1VF75/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HIR7-1", "protein_name": "THO complex subunit 7 homolog isoform X2", "gene_name": "Thoc7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDDKLSEVDEAQESAMEADPKP", "length": 152 }, "evidence": [ { "id": "A0A4X1VF75", "url": "https://omabrowser.org/oma/group/A0A4X1VF75/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3SZ60-1", "protein_name": "THO complex subunit 7 homolog", "gene_name": "THOC7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGAVTDDEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEVEEAQEASMETDPKP", "length": 204 }, "evidence": [ { "id": "A0A4X1VF75", "url": "https://omabrowser.org/oma/group/A0A4X1VF75/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q552L5-1", "protein_name": "THO complex subunit 7 homolog", "gene_name": "thoc7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIKKLLEDEEDSFFKNKIVFKNFVIKKVFKKYLQFINVTTGNNENSSVDLQSLCTQLINEFGHLELSVQKAQTISETCTDETLYYQQLSKQREIEIENEKKEIAILKETLDYEKKQRQYKEQYLALYKAINEKPSTEQTEKEIEKAQKELNEITDQTNKTTSKLELRTKQFQLLLHTLNELEKNLDESIPFIENSNNNNNNSNSDQSNTPMES", "length": 215 }, "evidence": [ { "id": "A0A4X1VF75", "url": "https://omabrowser.org/oma/group/A0A4X1VF75/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6DGZ3-1", "protein_name": "THO complex subunit 7 homolog", "gene_name": "thoc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSITDDEVIRKRLLIDGDGAGDDRRINVLMKSFTKWCHSSFSPEEGMSQYQRMMMSLAQCEFSMGKTLLVYNMNLKEMENYEGIYTDIEKSIASAHEKIAECKKEIQRAKRIRKNRQEYDALARVIKQHPDRHETLKQLEALDKDLQQLSHIKENVEDKLELRKKQFHVLLTTIQELQQTLENDEKMESDDTQDSPMENGD", "length": 202 }, "evidence": [ { "id": "A0A4X1VF75", "url": "https://omabrowser.org/oma/group/A0A4X1VF75/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6I9Y2-1", "protein_name": "THO complex subunit 7", "gene_name": "THOC7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAVTDDEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEVEEAQEASMETDPKP", "length": 204 }, "evidence": [ { "id": "A0A4X1VF75", "url": "https://omabrowser.org/oma/group/A0A4X1VF75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMY4-1", "protein_name": "THO complex subunit 7 homolog", "gene_name": "Thoc7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAVTDDEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDDKLSEVDEAQESTMEADPKP", "length": 204 }, "evidence": [ { "id": "A0A4X1VF75", "url": "https://omabrowser.org/oma/group/A0A4X1VF75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IRJ8-2", "protein_name": "THO complex protein 7", "gene_name": "thoc7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSEQCQLRPHSDTLVRKLVEMNDEEIIKQRLLIDGDGTGEDRRIVVLLKQFLKWASDSLDSNPIMYDRLMAQFAQCKLTALKNVQTLQMIAGERDNYTQLVEHHEESIVLAKAEIESSKKELITAKQIRKNKMEYDLLASLIQDQPDRSETQRHIETIRREIDDLVQKKLKMERKFQKRRNDFTLLMYTIHELEQQLDQDSSSSASSSSSDCDARSEPDLDDNGIMEVSDEDDDLNNSTPTKFDGARGEPKYHSVSTEDSKAMSVEEDTVLELSIDKDEHDVDVAVAN", "length": 288 }, "evidence": [ { "id": "A0A4X1VF75", "url": "https://omabrowser.org/oma/group/A0A4X1VF75/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8LDS5-1", "protein_name": "THO complex subunit 7A", "gene_name": "THO7A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSVRARRIVSGRSETVAANYAFDPLHDDKIIRNRLLTRTTTTRGEPPLKKLQKKFTSFVIELDKEEDNYSECGRLAKAFLQELSAFEIPLLKSQVVVAANLREKENFNELKDETNRQIMQAQADIEDLKKQLEESKIERQQKEECEAIRKLISAQPPRSETQKVIHELKKEIAELEAENTASWRLLELRKKQFALLLHVVDELQETMEDEQKSMVEEMQRNITADGAEAMSID", "length": 233 }, "evidence": [ { "id": "A0A4X1VF75", "url": "https://omabrowser.org/oma/group/A0A4X1VF75/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VF75", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VF75", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "THO complex part of transcription export complex", "id": "GO:0000445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000445", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VF75", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VF75", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VF75", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VF75", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VF75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U9K3-1", "uniprot_ac": "A0A4X1U9K3", "uniprot_id": "A0A4X1U9K3_PIG", "mass": { "chemical_mass": 64381.0, "monoisotopic_mass": 64381.0 }, "refseq": {}, "gene_names": [ { "name": "RUNX1T1", "type": "recommended", "evidence": [ { "id": "A0A4X1U9K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3" } ] } ], "protein_names": [ { "name": "RUNX1 partner transcriptional co-repressor 1", "type": "synonym", "evidence": [ { "id": "A0A4X1U9K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9K3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RUNX1T1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3", "locus": { "chromosome": "4", "start_pos": 44743418, "end_pos": 44599760, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006115", "url": "https://www.ensembl.org/id/ENSSSCG00000006115" } ] } } ], "crossref": [ { "id": "A0A4X1U9K3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U9K3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006115", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006115", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013289", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013289", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HDMIATE", "url": "https://omabrowser.org/oma/group/HDMIATE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10379:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10379:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287A9Z0", "url": "https://www.uniprot.org/uniprotkb/A0A287A9Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A9Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A9Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BF47", "url": "https://www.uniprot.org/uniprotkb/A0A287BF47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BF47-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BF47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U9K3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U9K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8X1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RY37", "url": "https://www.uniprot.org/uniprotkb/F1RY37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RY37-1", "url": "https://www.uniprot.org/uniprotkb/F1RY37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPDRTEKHSTMPDSPVDVKTPSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 577, "header": "tr|A0A4X1U9K3-1|A0A4X1U9K3_PIG Isoform 1 of RUNX1 partner transcriptional co-repressor 1 OS=Sus scrofa OX=9823 GN=RUNX1T1 PE=3 SV=1 CANONICAL=A0A4X1U9K3-1" }, "isoforms": [ { "isoform_ac": "A0A287A9Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3/entry#A0A287A9Z0-1", "sequence": { "sequence": "MVGLSGPVQYRTEKHSTMPDSPVDVKTPSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALEEAVNEVKRQAMTELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 561, "header": "tr|A0A287A9Z0-1|A0A4X1U9K3_PIG Computationally mapped isoform of RUNX1 partner transcriptional co-repressor 1 OS=Sus scrofa OX=9823 GN=RUNX1T1 PE=3 SV=2 CANONICAL=A0A4X1U9K3-1" }, "locus": { "chromosome": "4", "start_pos": 44742163, "end_pos": 44600242, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054962.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054962.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040759.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040759.2" } ] } }, { "isoform_ac": "A0A287BF47-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3/entry#A0A287BF47-1", "sequence": { "sequence": "MVGLSGPVQYRTEKHSTMPDSPVDVKTPSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 584, "header": "tr|A0A287BF47-1|A0A4X1U9K3_PIG Computationally mapped isoform of RUNX1 partner transcriptional co-repressor 1 OS=Sus scrofa OX=9823 GN=RUNX1T1 PE=3 SV=1 CANONICAL=A0A4X1U9K3-1" }, "locus": { "chromosome": "4", "start_pos": 44742163, "end_pos": 44600242, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037553.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037553.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055188.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055188.1" } ] } }, { "isoform_ac": "A0A4X1U9K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3/entry#A0A4X1U9K3-1", "sequence": { "sequence": "MPDRTEKHSTMPDSPVDVKTPSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 577, "header": "tr|A0A4X1U9K3-1|A0A4X1U9K3_PIG Isoform 1 of RUNX1 partner transcriptional co-repressor 1 OS=Sus scrofa OX=9823 GN=RUNX1T1 PE=3 SV=1 CANONICAL=A0A4X1U9K3-1" }, "locus": { "chromosome": "4", "start_pos": 44742163, "end_pos": 44639399, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059899.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059899.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056352.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056352.2" } ] } }, { "isoform_ac": "A0A8W4F8X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3/entry#A0A8W4F8X1-1", "sequence": { "sequence": "MCHPDKPFTSDKLRCVFNEYKATVWVPPRLRPLSCAPLPEAGGENLHLKISRGRKRNLPFVVWGEEEASPGLAVISHHLCYPDRTHGDRTEKHSTMPDSPVDVKTPSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 662, "header": "tr|A0A8W4F8X1-1|A0A4X1U9K3_PIG Computationally mapped isoform of RUNX1 partner transcriptional co-repressor 1 OS=Sus scrofa OX=9823 GN=RUNX1T1 PE=3 SV=1 CANONICAL=A0A4X1U9K3-1" }, "locus": { "chromosome": "4", "start_pos": 44742163, "end_pos": 44607689, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095606.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095606.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075828.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075828.1" } ] } }, { "isoform_ac": "F1RY37-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3/entry#F1RY37-1", "sequence": { "sequence": "MNTKPRSGCRLGCGRLSCAPLPEAGGENLHLKISRGRKRNLPFVVWGEEEASVLAWPLSPITSAIQTGLTEKRLISGLVNIISVPVRKGKRKLAERLVENDICQKKHLESTEFSNRYRTEKHSTMPDSPVDVKTPSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 691, "header": "tr|F1RY37-1|A0A4X1U9K3_PIG Computationally mapped isoform of RUNX1 partner transcriptional co-repressor 1 OS=Sus scrofa OX=9823 GN=RUNX1T1 PE=3 SV=5 CANONICAL=A0A4X1U9K3-1" }, "locus": { "chromosome": "4", "start_pos": 44742163, "end_pos": 44607741, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006707.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006707.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006525.5", "url": "https://www.ensembl.org/id/ENSSSCP00000006525.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 266, "start_aa": "Thr", "end_pos": 266, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr266", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 568, "start_aa": "Thr", "end_pos": 568, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr568", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F8X1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8X1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0G0-1", "protein_name": "RUNX1 partner transcriptional co-repressor 1", "gene_name": "Runx1t1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTKRRCGGRAAGRLARSPPEGNLRGRAGGGGAGRGVGAAPQRSRADKSQGSEDVTCYRELLLAARGNLHLKITEGEGEDLPFVVLGEEEAAALASLLSPNTSAIQTGTRGDRTEKHSTMPDSPVDVKTQSRLTPPAMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSGSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAPQQGETPAVSSSVTPSSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 686 }, "evidence": [ { "id": "A0A4X1U9K3", "url": "https://omabrowser.org/oma/group/A0A4X1U9K3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A1D5P838-1", "protein_name": "RUNX1 translocation partner 1", "gene_name": "RUNX1T1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 577 }, "evidence": [ { "id": "A0A4X1U9K3", "url": "https://omabrowser.org/oma/group/A0A4X1U9K3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AB32T784-1", "protein_name": "Protein CBFA2T1 isoform X1", "gene_name": "runx1t1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVGISTSFQSPPPPGTIWEMLLQSNERGFMRQKWLGDVCRLGMVYAGLTVSSDDRTEKRSTMPDSPADVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTALTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELVHCARLAKQNPAQYLAQHEQLLLDTSTTSPVDSSELLMDVNENGKRRTPDRTKENGFEREPLHPEHPNKRPCTISPGQRFSPSNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRELRDRPRPLGMHGSSTRQEEVIDHRLTDREWAEEWKHLDHVRKLLNCIMDMVEKTRRSLTVLRRCQETDREELNYWIRRYSDAEDLKKTSSTSTSQSRQQSPASQEGNALEVHRELLHRPVSGYVPEEIWKKAEEAVNEVKRQAMSELQKAVSEAERKAHEMISTERAKMERTVAEARRQAAEDALSVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHVCGQTLQAQQQGETPATVSSSATPSSGAGSPADTPSAAATPRSATPGTPSTVENTPR", "length": 635 }, "evidence": [ { "id": "A0A4X1U9K3", "url": "https://omabrowser.org/oma/group/A0A4X1U9K3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1N0Y4-1", "protein_name": "RUNX1 partner transcriptional co-repressor 1", "gene_name": "RUNX1T1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPDRTEKHSTMPDSPVDVKTPSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGSSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 576 }, "evidence": [ { "id": "A0A4X1U9K3", "url": "https://omabrowser.org/oma/group/A0A4X1U9K3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q06455-1", "protein_name": "Protein CBFA2T1", "gene_name": "RUNX1T1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISVKRNTWRALSLVIGDCRKKGNFEYCQDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGGSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 604 }, "evidence": [ { "id": "A0A4X1U9K3", "url": "https://omabrowser.org/oma/group/A0A4X1U9K3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61909-1", "protein_name": "Protein CBFA2T1", "gene_name": "Runx1t1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPDRTEKHSTMPDSPVDVKTQSRLTPPAMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAPQQGDTPAVSSSVTPSSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 577 }, "evidence": [ { "id": "A0A4X1U9K3", "url": "https://omabrowser.org/oma/group/A0A4X1U9K3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9K3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9K3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9K3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9K3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9K3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9K3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9K3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9K3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U9K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3" }, { "id": "PS50865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYND-type", "eco_id": "ECO_0000259", "start_pos": 488, "end_pos": 524, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1U9K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9K3" }, { "id": "PS51119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TAFH", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 188, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 266, 568 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VGN9-1", "uniprot_ac": "A0A4X1VGN9", "uniprot_id": "A0A4X1VGN9_PIG", "mass": { "chemical_mass": 58106.0, "monoisotopic_mass": 58106.0 }, "refseq": { "ac": "XP_013837243", "name": "actin-related protein 8 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013837243" }, "gene_names": [ { "name": "ACTR8", "type": "recommended", "evidence": [ { "id": "A0A4X1VGN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ] }, { "name": "ACTR8", "type": "synonym", "evidence": [ { "id": "XP_013837243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013837243" } ] } ], "protein_names": [ { "name": "Actin-related protein 8", "type": "recommended", "evidence": [ { "id": "A0A4X1VGN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9/entry#names_and_taxonomy" } ] }, { "name": "actin-related protein 8 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_013837243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013837243" } ] } ], "function": [ { "annotation": "Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ARK3", "url": "https://www.uniprot.org/uniprotkb/A0A287ARK3#function" }, { "database": "UniProtKB", "id": "ARBA00025560", "url": "https://www.uniprot.org/uniprotkb/ARBA00025560#function" }, { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9#function" } ] }, { "annotation": "Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ARK3", "url": "https://www.uniprot.org/uniprotkb/A0A287ARK3#function" }, { "database": "UniProtKB", "id": "ARBA00053143", "url": "https://www.uniprot.org/uniprotkb/ARBA00053143#function" }, { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ACTR8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9", "locus": { "chromosome": "13", "start_pos": 35963945, "end_pos": 35987140, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011458", "url": "https://www.ensembl.org/id/ENSSSCG00000011458" } ] } } ], "crossref": [ { "id": "A0A4X1VGN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1VGN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000048844", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000048844", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10206", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10206", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100154005", "url": "https://www.ncbi.nlm.nih.gov/gene/100154005", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154005", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154005", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYKCMWA", "url": "https://omabrowser.org/oma/group/AYKCMWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287ARK3", "url": "https://www.orthodb.org/?gene=A0A287ARK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1VGN9", "url": "https://www.orthodb.org/?gene=A0A4X1VGN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5689603", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013837243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013837243", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287ARK3", "url": "https://www.uniprot.org/uniprotkb/A0A287ARK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ARK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ARK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VGN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNKWTNTSHHPEFLVGEEALYVNPLDCYNIHWPIRRGQLNIHQGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATFGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLGSSQGDCLMAGNDSEEALTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW", "length": 513, "header": "tr|A0A4X1VGN9-1|A0A4X1VGN9_PIG Isoform 1 of Actin-related protein 8 OS=Sus scrofa OX=9823 GN=ACTR8 PE=3 SV=1 CANONICAL=A0A4X1VGN9-1" }, "isoforms": [ { "isoform_ac": "A0A287ARK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9/entry#A0A287ARK3-1", "sequence": { "sequence": "MTQAEKGDAENGKEKGGEKEKEQRGVKRPIVPALVPESLQEQIQSNFIVVIHPGSTTLRIGRATDTLPASIPHVIARRHKQQGQPLYKDNWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNKWTNTSHHPEFLVGEEALYVNPLDCYNIHWPIRRGQLNIHQGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATFGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLGSSQGDCLMAGNDSEEALTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW", "length": 624, "header": "tr|A0A287ARK3-1|A0A4X1VGN9_PIG Computationally mapped isoform of Actin-related protein 8 OS=Sus scrofa OX=9823 GN=ACTR8 PE=3 SV=3 CANONICAL=A0A4X1VGN9-1" }, "locus": { "chromosome": "13", "start_pos": 35987053, "end_pos": 35964014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041214.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041214.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046534.3", "url": "https://www.ensembl.org/id/ENSSSCP00000046534.3" } ] } }, { "isoform_ac": "A0A4X1VGN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9/entry#A0A4X1VGN9-1", "sequence": { "sequence": "MVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNKWTNTSHHPEFLVGEEALYVNPLDCYNIHWPIRRGQLNIHQGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATFGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLGSSQGDCLMAGNDSEEALTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW", "length": 513, "header": "tr|A0A4X1VGN9-1|A0A4X1VGN9_PIG Isoform 1 of Actin-related protein 8 OS=Sus scrofa OX=9823 GN=ACTR8 PE=3 SV=1 CANONICAL=A0A4X1VGN9-1" }, "locus": { "chromosome": "13", "start_pos": 35973414, "end_pos": 35964014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053516.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053516.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034633.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034633.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ARK3", "url": "https://www.uniprot.org/uniprotkb/A0A287ARK3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154005", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154005", "resource": "KEGG Pathway" }, { "id": "R-SSC-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "resource": "Reactome", "description": "UCH proteinases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LPE7-1", "protein_name": "Actin-related protein 8", "gene_name": "Actr8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPSCSSSPRAFSPFLRFEVPGLHHHQKQKKEKSNFNRVVPSVPESSTGDAGGGHLDCGQPGDAAPARWFSTAYCGVGVPEPRGCWWSVVAEMTQAEKGDAENGKEKGGEKEKEQRGVKRPIVPALVPESLQEQIQSNFIVVVHPGSTTLRIGRATDTLPASIPHVIARRHKQQGQPLYKDNWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQTRSYNKQMRPAILDHCSGNKWTNTSHQPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVHMILMKMGFAGIVVHQESVCATFGSGLSSTCVVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLANKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLASSQGDCLMAGNESEEALTALMSRKTAISLFEGKALGLDKAILHSVDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKVSCFAI", "length": 675 }, "evidence": [ { "id": "A0A4X1VGN9", "url": "https://omabrowser.org/oma/group/A0A4X1VGN9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GUU0-1", "protein_name": "Actin-related protein 8", "gene_name": "Actr8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTQAEKGDAENGKEKGGEKEKEQRGVKRPIVPALVPESLQEQIQSNFIVVIHPGSTTLRIGRATDTLPASIPHVIARRHKQQGQPLYKDNWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNKWTNTSHQPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVHMILMKMGFSGIVVHQESVCATFGSGLSSTCVVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHPQEVDLASSQGDCLMAGNDSEEALTALMSRKTAISLFEGKALGLDKAILHSVDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW", "length": 624 }, "evidence": [ { "id": "A0A4X1VGN9", "url": "https://omabrowser.org/oma/group/A0A4X1VGN9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q12386-1", "protein_name": "Actin-like protein ARP8", "gene_name": "ARP8", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSQEEAESSIIYEEPIDIPLEDDDDEDELEEENSVPLSSQADQENAENESDDSVDNVVGSETPRSVTGLSVDPRDVADEEDEDEEGEDEDEDEDDNDVDNEDENDNDNANENENELGSSRDKRAPPAVQTSKRYKKYPKLDPAKAPPGKKVPLHLLEKRRLGRIKAAEEFAKTLKKIGIEKVETTTLPATGLFQPLMLINQKNYSSDYLKKDDQIFALRDRKFLRNNNTSQISSTNTPDVIDLKSLPHSEASAAPLNDEIDLNDPTATIVIHPGSNSIKIGFPKDDHPVVVPNCVAVPKKWLDLENSEHVENVCLQREQSEEFNNIKSEMEKNFRERMRYYKRKVPGNAHEQVVSFNENSKPEIISEKNDPSPIEWIFDDSKLYYGSDALRCVDEKFVIRKPFRGGSFNVKSPYYKSLAELISDVTKLLEHALNSETLNVKPTKFNQYKVVLVIPDIFKKSHVETFIRVLLTELQFQAVAIIQESLATCYGAGISTSTCVVNIGAAETRIACVDEGTVLEHSAITLDYGGDDITRLFALFLLQSDFPLQDWKIDSKHGWLLAERLKKNFTTFQDADVAVQLYNFMNRSPNQPTEKYEFKLFDEVMLAPLALFFPQIFKLIRTSSHKNSSLEFQLPESRDLFTNELNDWNSLSQFESKEGNLYCDLNDDLKILNRILDAHNIIDQLQDKPENYGNTLKENFAPLEKAIVQSIANASITADVTRMNSFYSNILIVGGSSKIPALDFILTDRINIWRPSLLSSASFPQFYKKLTKEIKDLEGHYVNAPDKTEDENKQILQAQIKEKIVEELEEQHQNIEHQNGNEHIFPVSIIPPPRDMNPALIIWKGASVLAQIKLVEELFITNSDWDVHGSRILQYKCIFTY", "length": 881 }, "evidence": [ { "id": "A0A4X1VGN9", "url": "https://omabrowser.org/oma/group/A0A4X1VGN9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q1LZF2-1", "protein_name": "Actin-related protein 8", "gene_name": "ACTR8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTQAEKGEAENGKEKGGEKEKEQRGVKRPIVPALVPESLQEQIQSNFIVVIHPGSTTLRIGRATDTLPASVPHVIARRHKQQGQPLYKDSWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNKWTNTSHHPEFLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATFGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEQYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLGPSQGDCLMAGNDSEEALTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDETKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW", "length": 624 }, "evidence": [ { "id": "A0A4X1VGN9", "url": "https://omabrowser.org/oma/group/A0A4X1VGN9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R2S9-1", "protein_name": "Actin-related protein 8", "gene_name": "Actr8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTQAEKGDAENGKEKGGEKEKEQRGVKRPIVPALVPESLQEQIQSNFIVVIHPGSTTLRLGRATDTLPVSVPHVIARRHKQQGQPLYKDNWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQTRSYNKQMRPAILDHCSGNKWTNTSQQPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVHMILMKMGFAGIVVHQESVCATFGSGLSSTCVVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLASSQGDCLMAGNESEEALTALMSRKTAISLFEGKALGLDKAILHSVDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW", "length": 624 }, "evidence": [ { "id": "A0A4X1VGN9", "url": "https://omabrowser.org/oma/group/A0A4X1VGN9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H981-1", "protein_name": "Actin-related protein 8", "gene_name": "ACTR8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQAEKGDTENGKEKGGEKEKEQRGVKRPIVPALVPESLQEQIQSNFIIVIHPGSTTLRIGRATDTLPASIPHVIARRHKQQGQPLYKDSWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNKWTNTSHHPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATYGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLGSAQGDGLMAGNDSEEALTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW", "length": 624 }, "evidence": [ { "id": "A0A4X1VGN9", "url": "https://omabrowser.org/oma/group/A0A4X1VGN9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VX09-1", "protein_name": "Actin-related protein 8", "gene_name": "Arp8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQRSRASSTSSGRHPAPPPIGLPQPQAQPLEAPKIIVIHPGSQHLRIGRAADLNPLTLLHAVAYRRRPGASDRPHHDPLLPPLDNVNSNSGLMVEFEEQRLVVSRILQHCVVDNKNRLRVATPPQQLAHFNRSSQAEKVPAPSGQMADEPWLDREAPVLFDDRILRLGAVDARNYDIHFPIQRGELNVHNEKGGSLQASMQHLERIWSYALEERLKIPLRKLGTHCAVLVVNDVYVRRHLREFVTLLLRRLGFRRCFLVQDSVASTFGAGIGYGCVVDIGAQKTSIACIEDGISQLDARVRLSYGGGDLDQVLLLLLRKCGFPYRECNVQESYVDAHLLDELKEKFCHLNASVCGAQEKHFNLRKHNGQWLRYTIQVGDEALMAPLALFHTELLNITGRTKAVFTQQAVQDQYDCEDCFDAEYLKETGRKNGVRGGDILQLSTSAGYQPRPQLPVTADDEELIVVDQDETISNCQSQLGAQTAGGQMNSNGCYHNGQGLVLPLDQAIIQSINRLSSYETKRKMFGSILLVGSSAKLPGLAAWLEQRISQQVQSEVNVLIKGMDAGMVAWKGAAIMSVLESARELWISQNDWQRHGLRVLRERSPFLW", "length": 607 }, "evidence": [ { "id": "A0A4X1VGN9", "url": "https://omabrowser.org/oma/group/A0A4X1VGN9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 18, "go_terms": [ { "name": "regulation of DNA strand elongation", "id": "GO:0060382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060382", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "regulation of embryonic development", "id": "GO:0045995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045995", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "positive regulation of telomere maintenance in response to DNA damage", "id": "GO:1904507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904507", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "regulation of chromosome organization", "id": "GO:0033044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033044", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "positive regulation of macromolecule metabolic process", "id": "GO:0010604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010604", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "regulation of DNA metabolic process", "id": "GO:0051052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051052", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "Ino80 complex", "id": "GO:0031011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031011", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1V8Q3-1", "uniprot_ac": "A0A4X1V8Q3", "uniprot_id": "A0A4X1V8Q3_PIG", "mass": { "chemical_mass": 45498.0, "monoisotopic_mass": 45498.0 }, "refseq": {}, "gene_names": [ { "name": "MAEL", "type": "recommended", "evidence": [ { "id": "A0A4X1V8Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ] } ], "protein_names": [ { "name": "Protein maelstrom homolog", "type": "recommended", "evidence": [ { "id": "A0A4X1V8Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VC66", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VC66#function" }, { "database": "UniProtKB", "id": "ARBA00025698", "url": "https://www.uniprot.org/uniprotkb/ARBA00025698#function" }, { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3#function" }, { "database": "UniProtKB", "id": "A0A4X1VEW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEW7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MAEL", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3", "locus": { "chromosome": "4", "start_pos": 83990273, "end_pos": 84040465, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006316", "url": "https://www.ensembl.org/id/ENSSSCG00000006316" } ] } } ], "crossref": [ { "id": "A0A4X1V8Q3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1V8Q3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006316", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006316", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21992", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21992", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KHEIFDH", "url": "https://omabrowser.org/oma/group/KHEIFDH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21358", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21358", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21358:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21358:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09011", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09011", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V8Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VC66", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VC66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VC66-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VC66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VEW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VEW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNRRGSRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWAKPVSTPLRRPAMLVPKQNVSPPDMSCLSLKSDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISHFESGHDQATVLQNLYRFIRPNSGKWPPIYCKSDDRARVNWCLKYMAKSSEIRQDLELVTVEDLVVGIYQQKFLKEPSKTWVRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCRKIAYCISNSLATLLGIQLTEAHVPLQDYETSNSVTPKMVVLDAGRYQKLRVESSGFSHFSSSNQEQRSNTPTGDYPSGVKISGQSSSVRGRGITRLLESISNSSSNIHKFSTCESSLSPYMSQKDGYKSFSSLS", "length": 403, "header": "tr|A0A4X1V8Q3-1|A0A4X1V8Q3_PIG Isoform 1 of Protein maelstrom homolog OS=Sus scrofa OX=9823 GN=MAEL PE=3 SV=1 CANONICAL=A0A4X1V8Q3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1V8Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3/entry#A0A4X1V8Q3-1", "sequence": { "sequence": "MPNRRGSRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWAKPVSTPLRRPAMLVPKQNVSPPDMSCLSLKSDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISHFESGHDQATVLQNLYRFIRPNSGKWPPIYCKSDDRARVNWCLKYMAKSSEIRQDLELVTVEDLVVGIYQQKFLKEPSKTWVRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCRKIAYCISNSLATLLGIQLTEAHVPLQDYETSNSVTPKMVVLDAGRYQKLRVESSGFSHFSSSNQEQRSNTPTGDYPSGVKISGQSSSVRGRGITRLLESISNSSSNIHKFSTCESSLSPYMSQKDGYKSFSSLS", "length": 403, "header": "tr|A0A4X1V8Q3-1|A0A4X1V8Q3_PIG Isoform 1 of Protein maelstrom homolog OS=Sus scrofa OX=9823 GN=MAEL PE=3 SV=1 CANONICAL=A0A4X1V8Q3-1" }, "locus": { "chromosome": "4", "start_pos": 84040398, "end_pos": 83990525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072449.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072449.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073249.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073249.1" } ] } }, { "isoform_ac": "A0A4X1VC66-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3/entry#A0A4X1VC66-1", "sequence": { "sequence": "MPNRRGSRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWALLREEEKEKYSEMAREWKAAQGKDAGPWEKQKPVSTPLRRPAMLVPKQNVSPPDMSCLSLKSDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISHFESGHDQATVLQNLYRFIRPNSGKWPPIYCKSDDRARVNWCLKYMAKSSEIRQDLELVTVEDLVVGIYQQKFLKEPSKTWVRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCRKIAYCISNSLATLLGIQLTEAHVPLQDYETSNSVTPKMVVLDAGRYQKLRVESSGFSHFSSSNQEQRSNTPTGDYPSGVKISGQSSSVRGRGITRLLESISNSSSNIHKFSTCESSLSPYMSQKDGYKSFSSLS", "length": 434, "header": "tr|A0A4X1VC66-1|A0A4X1V8Q3_PIG Computationally mapped isoform of Protein maelstrom homolog OS=Sus scrofa OX=9823 GN=MAEL PE=3 SV=1 CANONICAL=A0A4X1V8Q3-1" }, "locus": { "chromosome": "4", "start_pos": 84040398, "end_pos": 83990525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083778.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083778.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060486.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060486.2" } ] } }, { "isoform_ac": "A0A4X1VEW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3/entry#A0A4X1VEW7-1", "sequence": { "sequence": "MPNRRGSRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWALLREEEKEKYSEMAREWKAAQGKDAGPWEKQKPVSTPLRRPAMLVPKQNVSPPDMSCLSLKSDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMPARVDIPISHFESGHDQATVLQNLYRFIRPNSGKWPPIYCKSDDRARVNWCLKYMAKSSEIRQDLELVTVEDLVVGIYQQKFLKEPSKTWVRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCRKIAYCISNSLATLLGIQLTEAHVPLQDYETSNSVTPKMVVLDAGRYQKLRVESSGFSHFSSSNQEQRSNTPTGDYPSGVKISGQSSSVRGRGITRLLESISNSSSNIHKFSTCESSLSPYMSQKDGYKSFSSLS", "length": 410, "header": "tr|A0A4X1VEW7-1|A0A4X1VEW7_PIG Computationally mapped isoform of Protein maelstrom homolog OS=Sus scrofa OX=9823 GN=MAEL PE=3 SV=1 CANONICAL=A0A4X1V8Q3-1" }, "locus": { "chromosome": "4", "start_pos": 84040398, "end_pos": 83990525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006923.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006923.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006734.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006734.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VC66", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VC66" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HLS8-1", "protein_name": "Protein maelstrom homolog", "gene_name": "Mael", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPNRRASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWALLREDEKEKYSEMAREWRAAQGKDSGPSEKQKFISTPLRRPGMLVPRPSVSPPDMSNLSIKSDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFIHPGEIPRGFRFHCQAASDSSHKIPISNFEFGHDQATVLKNLYKFIHPNPGNWPPIYCKSDDRARVNWCLKRMERASEIRQDLELLTVEDLVVGIYQQKFLKEPSKTWVRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCKKIAYCISNSLATLFGIQLTGAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVESPGFCHFNSYNQEQRSNTSTGYYPSGVKISGPNSSVRGRGITRLLESISSSSNNIHRFSNCETSLSPYMSQKDGYKSFSSFS", "length": 434 }, "evidence": [ { "id": "A0A4X1V8Q3", "url": "https://omabrowser.org/oma/group/A0A4X1V8Q3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9TLU3-1", "protein_name": "Protein maelstrom homolog", "gene_name": "MAEL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPNRRASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWAKPVCTPLRKPGMLVPKQNVSPPDLSGLSLKSDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISHFESGHDQATVLENLYRFIHPNPGNWPPIYCKSDDRARVNWCLKHMAKSSEIRQDLELLTVEDLVVGIYQQKFLKEPSKTWVRSLLEVAMWDYSSNTRCKWHEENDILFCALAVCKKIAYCISNSLATLFGIQLTEAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVESPGFSHFSSSNQEQRSNTPTGDYPSGVKISGQNSSVRGRGITRLLESISSSSSNIHKFSNCETPVSPYTSPKHGYKSFSSLS", "length": 403 }, "evidence": [ { "id": "A0A4X1V8Q3", "url": "https://omabrowser.org/oma/group/A0A4X1V8Q3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0L854-1", "protein_name": "Protein maelstrom homolog", "gene_name": "Mael", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPNRRASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWALLREDEKEKYSEMAREWRAAQGKDSGPSEKQGLVMAHWLKARATLPEDPVSSQCTYMKLVSTPLRRPGMLVPKPSVSPPDMSNLSIKSDQALLGGVFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISNFEFGHDQATVLQNLYKFIHPNPGNWPPIYCKSDDRARVNWCLKRMERASEIRQDLELLTVEDLVVGIYQQKFLKEPSKTWVRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCKKIAYCISNSLATLFGIQLTGAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVESPGFCHFNSYNQEQRSNSSTGYYPSGVKISGSNSSVRGRGITRLLESISNSSNNIHRFSNCEASLSPYMPQKDGYKPFSSFS", "length": 460 }, "evidence": [ { "id": "A0A4X1V8Q3", "url": "https://omabrowser.org/oma/group/A0A4X1V8Q3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BVN9-1", "protein_name": "Protein maelstrom homolog", "gene_name": "Mael", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPNRRASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWALLREDEKEKYSEMAREWRAAQGKDSGPSEKQKLVSTPLRRPGMLVPKPSISPPDMSNLSIKSDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFIHPGEIPRGFRFHCQAASDSSHKIPISNFEFGHDQATVLQNLYKFIHPNPGNWPPIYCKSDDRARVNWCLKRMERASEIRQDLELLTVEDLVVGIYQQKFLKEPSKTWVRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCKKIAYCISNSLATLFGIQLTGAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVESPGFCHFNSYNQEQRSNTSTGYYPSGVKISGPHSSVRGRGITRLLESISNSSNNIHRFSSCETSLSPYTPQKDGYKPFSSFS", "length": 434 }, "evidence": [ { "id": "A0A4X1V8Q3", "url": "https://omabrowser.org/oma/group/A0A4X1V8Q3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JY0-1", "protein_name": "Protein maelstrom homolog", "gene_name": "MAEL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPNRKASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSSDWALLREEEKEKYAEMAREWRAAQGKDPGPSEKQKPVFTPLRRPGMLVPKQNVSPPDMSALSLKGDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISNFERGHNQATVLQNLYRFIHPNPGNWPPIYCKSDDRTRVNWCLKHMAKASEIRQDLQLLTVEDLVVGIYQQKFLKEPSKTWIRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCKKIAYCISNSLATLFGIQLTEAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVGSSGFSHFNSSNEEQRSNTPIGDYPSRAKISGQNSSVRGRGITRLLESISNSSSNIHKFSNCDTSLSPYMSQKDGYKSFSSLS", "length": 434 }, "evidence": [ { "id": "A0A4X1V8Q3", "url": "https://omabrowser.org/oma/group/A0A4X1V8Q3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "XY body", "id": "GO:0001741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001741", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "chromatoid body", "id": "GO:0033391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033391", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "piP-body", "id": "GO:0071547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071547", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "autosome", "id": "GO:0030849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030849", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "P granule", "id": "GO:0043186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043186", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "regulation of miRNA-mediated gene silencing", "id": "GO:0060964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060964", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "male meiotic nuclear division", "id": "GO:0007140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007140", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "piRNA processing", "id": "GO:0034587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034587", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" }, { "name": "transposable element silencing by piRNA-mediated DNA methylation", "id": "GO:0141196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141196", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1V8Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" }, { "id": "PF09011", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 44, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1V8Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8Q3" }, { "id": "PF13017", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Maelstrom", "eco_id": "ECO_0000259", "start_pos": 99, "end_pos": 295, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 371, "end_pos": 373 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UW95-1", "uniprot_ac": "A0A4X1UW95", "uniprot_id": "A0A4X1UW95_PIG", "mass": { "chemical_mass": 18005.0, "monoisotopic_mass": 18005.0 }, "refseq": {}, "gene_names": [ { "name": "CHP1", "type": "recommended", "evidence": [ { "id": "A0A4X1UW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ] } ], "protein_names": [ { "name": "Calcineurin like EF-hand protein 1", "type": "synonym", "evidence": [ { "id": "A0A4X1UW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CHP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95", "locus": { "chromosome": "1", "start_pos": 130073928, "end_pos": 130112751, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004751", "url": "https://www.ensembl.org/id/ENSSSCG00000004751" } ] } } ], "crossref": [ { "id": "A0A4X1UW95", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UW95", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100621371", "url": "https://www.ncbi.nlm.nih.gov/gene/100621371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621371", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LKFAFRM", "url": "https://omabrowser.org/oma/group/LKFAFRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UW85", "url": "https://www.orthodb.org/?gene=A0A4X1UW85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13405", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13405", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2160916", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2160916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UW85", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UW85-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UW95-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1HEQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HEQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1HEQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HEQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDMNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLEKVDVEQKMSIRFLH", "length": 154, "header": "tr|A0A4X1UW95-1|A0A4X1UW95_PIG Isoform 1 of Calcineurin like EF-hand protein 1 OS=Sus scrofa OX=9823 GN=CHP1 PE=1 SV=1 CANONICAL=A0A4X1UW95-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UW85-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95/entry#A0A4X1UW85-1", "sequence": { "sequence": "MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDMNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFLH", "length": 195, "header": "tr|A0A4X1UW85-1|A0A4X1UW95_PIG Computationally mapped isoform of Calcineurin like EF-hand protein 1 OS=Sus scrofa OX=9823 GN=CHP1 PE=1 SV=1 CANONICAL=A0A4X1UW95-1" }, "locus": { "chromosome": "1", "start_pos": 130112218, "end_pos": 130075844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005250.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005250.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005123.3", "url": "https://www.ensembl.org/id/ENSSSCP00000005123.3" } ] } }, { "isoform_ac": "A0A4X1UW95-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95/entry#A0A4X1UW95-1", "sequence": { "sequence": "MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDMNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLEKVDVEQKMSIRFLH", "length": 154, "header": "tr|A0A4X1UW95-1|A0A4X1UW95_PIG Isoform 1 of Calcineurin like EF-hand protein 1 OS=Sus scrofa OX=9823 GN=CHP1 PE=1 SV=1 CANONICAL=A0A4X1UW95-1" }, "locus": { "chromosome": "1", "start_pos": 130112218, "end_pos": 130075844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074266.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074266.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074046.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074046.1" } ] } }, { "isoform_ac": "A0A8D1HEQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95/entry#A0A8D1HEQ6-1", "sequence": { "sequence": "MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLRAKKWVTLTLVYVDREHGHRLATPFPKQKDYVPEDPSCTWLKPFPVYRNSLRGSAETDLTSTHEDTGLIPGLAHREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDMNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFLH", "length": 268, "header": "tr|A0A8D1HEQ6-1|A0A4X1UW95_PIG Computationally mapped isoform of Calcineurin like EF-hand protein 1 OS=Sus scrofa OX=9823 GN=CHP1 PE=1 SV=1 CANONICAL=A0A4X1UW95-1" }, "locus": { "chromosome": "1", "start_pos": 130112218, "end_pos": 130075844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044283.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044283.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054689.2", "url": "https://www.ensembl.org/id/ENSSSCP00000054689.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1HEQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HEQ6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621371", "resource": "KEGG Pathway" }, { "id": "R-SSC-2160916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2160916", "resource": "Reactome", "description": "Hyaluronan degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "P61022-1", "protein_name": "Calcineurin B homologous protein 1", "gene_name": "Chp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFSEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFLH", "length": 195 }, "evidence": [ { "id": "A0A4X1UW95", "url": "https://omabrowser.org/oma/group/A0A4X1UW95/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61023-1", "protein_name": "Calcineurin B homologous protein 1", "gene_name": "Chp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFSEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFLH", "length": 195 }, "evidence": [ { "id": "A0A4X1UW95", "url": "https://omabrowser.org/oma/group/A0A4X1UW95/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3SYS6-1", "protein_name": "Calcineurin B homologous protein 1", "gene_name": "CHP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFLH", "length": 195 }, "evidence": [ { "id": "A0A4X1UW95", "url": "https://omabrowser.org/oma/group/A0A4X1UW95/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54MF3-1", "protein_name": "Calcineurin subunit B type 2", "gene_name": "cnbB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGVSRSTLRTEEIEEIREVSIFSQREIKRLYKRFKRLDKEEKGSINVEDFNQIPELSMNPMLPRIISIFDVNRDGQVNFKQFVKSLSTFHPKADKADKIKILFKVYDINNDGFITRDEIETILTMMVGSNLTKEQISSIVEETLNEADVNGKGKLDYPDFYNSIGSSGCNAENMLSISFNPFE", "length": 183 }, "evidence": [ { "id": "A0A4X1UW95", "url": "https://omabrowser.org/oma/group/A0A4X1UW95/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5ZM44-1", "protein_name": "Calcineurin B homologous protein 1", "gene_name": "CHP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGSRASTLLRDEEIEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFSEGEDQVNFRGFMRTLAHFRPIEDNEKSKDQNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDCAISFAEFVKVLEKVDVEQKMSIRFLH", "length": 195 }, "evidence": [ { "id": "A0A4X1UW95", "url": "https://omabrowser.org/oma/group/A0A4X1UW95/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q99653-1", "protein_name": "Calcineurin B homologous protein 1", "gene_name": "CHP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFLH", "length": 195 }, "evidence": [ { "id": "A0A4X1UW95", "url": "https://omabrowser.org/oma/group/A0A4X1UW95/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LS47-1", "protein_name": "Calcium-binding EF-hand family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGNTSSMLTQYDIEEVQSHCHDLFEQQEILSLYQRFCQLDRNAKGFISADEFLSVPEFAMNPLSQRLLKMVDGLNFKDFVAFLSAFSAKASLRQKVQLIFKVYDSDCNGKVSFKDIMEVLRDLSGSFMSDEQREQVLSQVLKESGYTSDSFLTLEDFIKIFGSSRPEMDVEIPVD", "length": 175 }, "evidence": [ { "id": "A0A4X1UW95", "url": "https://omabrowser.org/oma/group/A0A4X1UW95/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VNF9-1", "protein_name": "Ethanol sensitive with low memory, isoform B", "gene_name": "elm", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGNKSSLFLRNEEIAQIQEETGFTPNQIERLYSRFTSLDRNDCGTLSREDLMRIPELAINPLCERIVHSFFAESNDDRVNFRQFMNVLAHFRPLRDNKQSKLNSREEKLKFAFKMYDLDDDGVISRDELLSILHMMVGANISQDQLVSIAERTILEADLCCQGKISFEDFCKALDRTDVDQKMSIRFLN", "length": 189 }, "evidence": [ { "id": "A0A4X1UW95", "url": "https://omabrowser.org/oma/group/A0A4X1UW95/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" }, { "name": "transporter complex", "id": "GO:1990351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" }, { "name": "intracellular sodium ion homeostasis", "id": "GO:0006883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006883", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" }, { "name": "positive regulation of phospholipid biosynthetic process", "id": "GO:0071073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071073", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" }, { "name": "negative regulation of calcineurin-NFAT signaling cascade", "id": "GO:0070885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070885", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" }, { "name": "negative regulation of protein import into nucleus", "id": "GO:0042308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042308", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" }, { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" }, { "name": "membrane docking", "id": "GO:0022406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022406", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" }, { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" }, { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UW95", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UW95" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 61, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VH17-1", "uniprot_ac": "A0A4X1VH17", "uniprot_id": "A0A4X1VH17_PIG", "mass": { "chemical_mass": 27054.0, "monoisotopic_mass": 27054.0 }, "refseq": { "ac": "XP_020935097", "name": "protein lin-28 homolog B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935097" }, "gene_names": [ { "name": "LIN28B", "type": "recommended", "evidence": [ { "id": "A0A4X1VH17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ] }, { "name": "LIN28B", "type": "synonym", "evidence": [ { "id": "XP_020935097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935097" } ] } ], "protein_names": [ { "name": "Lin-28 homolog B", "type": "synonym", "evidence": [ { "id": "A0A4X1VH17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17/entry#names_and_taxonomy" } ] }, { "name": "protein lin-28 homolog B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020935097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935097" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LIN28B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17", "locus": { "chromosome": "1", "start_pos": 71296217, "end_pos": 71159251, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037612", "url": "https://www.ensembl.org/id/ENSSSCG00000037612" } ] } } ], "crossref": [ { "id": "A0A4X1VH17", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1VH17", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04458", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04458", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100738513", "url": "https://www.ncbi.nlm.nih.gov/gene/100738513", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46109:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46109:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21890", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21890", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020935097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935097", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1VED0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VED0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VED0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VED0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VH17-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGGASKGGGEEPGKLPEQAEEESQVLHGTGHCKWFNVRMGFGFISMISREGSPLDIPVDVFVHQSKLFMEGFRSLKEGEPVEFTFKKSSKGLESIRVTGPGGSPCLGSERRPKGKTLQKRKPKGDRCYNCGGLDHHAKECSLPPQPKKCHCCQSITHMVANCPHKTVVQAPTSSQGRQEAEPQPCTSTFPREVGGGHGCTSPPFPQEARSEISEWPGRSPQEASSVKSSAAPEEQSKKGPSVQKRKKT", "length": 250, "header": "tr|A0A4X1VH17-1|A0A4X1VH17_PIG Isoform 1 of Lin-28 homolog B OS=Sus scrofa OX=9823 GN=LIN28B PE=3 SV=1 CANONICAL=A0A4X1VH17-1" }, "isoforms": [ { "isoform_ac": "A0A4X1VED0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17/entry#A0A4X1VED0-1", "sequence": { "sequence": "MRSFNQVSSAPGGASKGGGEEPGKLPEQAEEESQVLHGTGHCKWFNVRMGFGFISMISREGSPLDIPVDVFVHQSKLFMEGFRSLKEGEPVEFTFKKSSKGLESIRVTGPGGSPCLGSERRPKGKTLQKRKPKGDRCYNCGGLDHHAKECSLPPQPKKCHCCQSITHMVANCPHKTVVQAPTSSQGRQEAEPQPCTSTFPREVGGGHGCTSPPFPQEARSEISEWPGRSPQEASSVKSSAAPEEQSKKGPSVQKRKKT", "length": 258, "header": "tr|A0A4X1VED0-1|A0A4X1VH17_PIG Computationally mapped isoform of Lin-28 homolog B OS=Sus scrofa OX=9823 GN=LIN28B PE=3 SV=1 CANONICAL=A0A4X1VH17-1" }, "locus": { "chromosome": "1", "start_pos": 71295213, "end_pos": 71166786, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043008.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043008.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054285.2", "url": "https://www.ensembl.org/id/ENSSSCP00000054285.2" } ] } }, { "isoform_ac": "A0A4X1VH17-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17/entry#A0A4X1VH17-1", "sequence": { "sequence": "MAEGGASKGGGEEPGKLPEQAEEESQVLHGTGHCKWFNVRMGFGFISMISREGSPLDIPVDVFVHQSKLFMEGFRSLKEGEPVEFTFKKSSKGLESIRVTGPGGSPCLGSERRPKGKTLQKRKPKGDRCYNCGGLDHHAKECSLPPQPKKCHCCQSITHMVANCPHKTVVQAPTSSQGRQEAEPQPCTSTFPREVGGGHGCTSPPFPQEARSEISEWPGRSPQEASSVKSSAAPEEQSKKGPSVQKRKKT", "length": 250, "header": "tr|A0A4X1VH17-1|A0A4X1VH17_PIG Isoform 1 of Lin-28 homolog B OS=Sus scrofa OX=9823 GN=LIN28B PE=3 SV=1 CANONICAL=A0A4X1VH17-1" }, "locus": { "chromosome": "1", "start_pos": 71295213, "end_pos": 71173718, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088401.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088401.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061562.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061562.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VED0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VED0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "RNA destabilization", "id": "GO:0050779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050779", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "negative regulation of primary miRNA processing", "id": "GO:2000635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000635", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "pre-miRNA processing", "id": "GO:0031054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031054", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "positive regulation of miRNA catabolic process", "id": "GO:2000627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000627", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "negative regulation of pre-miRNA processing", "id": "GO:2000632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000632", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "RNA 3'-end processing", "id": "GO:0031123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031123", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "miRNA catabolic process", "id": "GO:0010587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010587", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "regulation of miRNA-mediated gene silencing", "id": "GO:0060964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060964", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "post-transcriptional regulation of gene expression", "id": "GO:0010608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010608", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VH17", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1VH17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" }, { "id": "PS50158", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC-type", "eco_id": "ECO_0000259", "start_pos": 128, "end_pos": 142, "start_aa": "Arg", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1VH17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VH17" }, { "id": "PS51857", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51857" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CSD", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 101, "start_aa": "His", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TSZ3-1", "uniprot_ac": "A0A4X1TSZ3", "uniprot_id": "A0A4X1TSZ3_PIG", "mass": { "chemical_mass": 22541.0, "monoisotopic_mass": 22541.0 }, "refseq": { "ac": "NP_001229989", "name": "ras-related protein Rab-10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229989" }, "gene_names": [ { "name": "RAB10", "type": "recommended", "evidence": [ { "id": "A0A4X1TSZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ] }, { "name": "RAB10", "type": "synonym", "evidence": [ { "id": "NP_001229989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229989" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A4X1TSZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A4X1TSZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-10", "type": "synonym", "evidence": [ { "id": "NP_001229989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229989" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RAB10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3", "locus": { "chromosome": "3", "start_pos": 112829137, "end_pos": 112924269, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008573", "url": "https://www.ensembl.org/id/ENSSSCG00000008573" } ] } } ], "crossref": [ { "id": "A0A4X1TSZ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TSZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008573", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008573", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01867", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01867", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100526104", "url": "https://www.ncbi.nlm.nih.gov/gene/100526104", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100526104", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100526104", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ENIRTWF", "url": "https://omabrowser.org/oma/group/ENIRTWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TSZ3", "url": "https://www.orthodb.org/?gene=A0A4X1TSZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47980", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47980", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001229989", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229989", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TSZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QAT3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QAT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJU1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENVDISSGGGVTGWKSKCC", "length": 200, "header": "tr|A0A4X1TSZ3-1|A0A4X1TSZ3_PIG Isoform 1 of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB10 PE=1 SV=1 CANONICAL=A0A4X1TSZ3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TSZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3/entry#A0A4X1TSZ3-1", "sequence": { "sequence": "MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENVDISSGGGVTGWKSKCC", "length": 200, "header": "tr|A0A4X1TSZ3-1|A0A4X1TSZ3_PIG Isoform 1 of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB10 PE=1 SV=1 CANONICAL=A0A4X1TSZ3-1" }, "locus": { "chromosome": "3", "start_pos": 112923657, "end_pos": 112844628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009379.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009379.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009139.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009139.2" } ] } }, { "isoform_ac": "A0A5G2QAT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3/entry#A0A5G2QAT3-1", "sequence": { "sequence": "MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKPLKLHIVSHPKYLGPKDFEGRCCSETSL", "length": 201, "header": "tr|A0A5G2QAT3-1|A0A4X1TSZ3_PIG Computationally mapped isoform of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB10 PE=1 SV=1 CANONICAL=A0A4X1TSZ3-1" }, "locus": { "chromosome": "3", "start_pos": 112923657, "end_pos": 112837645, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066649.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066649.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060514.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060514.1" } ] } }, { "isoform_ac": "A0A5G2RJU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3/entry#A0A5G2RJU1-1", "sequence": { "sequence": "MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKWNFRTICLSRQRRSCQSLS", "length": 192, "header": "tr|A0A5G2RJU1-1|A0A4X1TSZ3_PIG Computationally mapped isoform of small monomeric GTPase OS=Sus scrofa OX=9823 GN=RAB10 PE=1 SV=1 CANONICAL=A0A4X1TSZ3-1" }, "locus": { "chromosome": "3", "start_pos": 112923657, "end_pos": 112830663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086403.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086403.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072214.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072214.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QAT3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAT3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100526104", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100526104", "resource": "KEGG Pathway" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MKJ3-1", "protein_name": "small monomeric GTPase", "gene_name": "Rab10", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKSKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENVDISSGGGVTGWKSKCC", "length": 200 }, "evidence": [ { "id": "A0A4X1TSZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TSZ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O15971-1", "protein_name": "Rab10", "gene_name": "Rab10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAKKTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVNKERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERVIIDRRNQEKAPGYSKCCA", "length": 204 }, "evidence": [ { "id": "A0A4X1TSZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TSZ3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O24466-1", "protein_name": "Ras-related protein RABE1a", "gene_name": "RABE1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAPPARARADYDYLIKLLLIGDSGVGKSCLLLRFSDGSFTTSFITTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDESSFNNIRNWIRNIEQHASDSVNKILVGNKADMDESKRAVPKSKGQALADEYGMKFFETSAKTNLNVEEVFFSIAKDIKQRLADTDARAEPQTIKINQSDQGAGTSQATQKSACCGT", "length": 216 }, "evidence": [ { "id": "A0A4X1TSZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TSZ3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P07560-1", "protein_name": "Ras-related protein SEC4", "gene_name": "SEC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSGLRTVSASSGNGKSYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDMETRVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSNKLVGVGNGKEGNISINSGSGNSSKSNCC", "length": 215 }, "evidence": [ { "id": "A0A4X1TSZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TSZ3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P35281-1", "protein_name": "Ras-related protein Rab-10", "gene_name": "Rab10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIEIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDQHANEDVERMLLRNKCDMDHKRVVPKGKGEQIAREHRIRFFETSAKANINIEKAFLTLPEDILRKTPVKEPNSENVDISSGGGVTGWKSKCC", "length": 200 }, "evidence": [ { "id": "A0A4X1TSZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TSZ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P61026-1", "protein_name": "Ras-related protein Rab-10", "gene_name": "RAB10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENVDISSGGGVTGWKSKCC", "length": 200 }, "evidence": [ { "id": "A0A4X1TSZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TSZ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61027-1", "protein_name": "Ras-related protein Rab-10", "gene_name": "Rab10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENVDISSGGGVTGWKSKCC", "length": 200 }, "evidence": [ { "id": "A0A4X1TSZ3", "url": "https://omabrowser.org/oma/group/A0A4X1TSZ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "endoplasmic reticulum tubular network organization", "id": "GO:0071786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071786", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "establishment of protein localization to endoplasmic reticulum membrane", "id": "GO:0097051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097051", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "regulated exocytosis", "id": "GO:0045055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045055", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "antigen processing and presentation", "id": "GO:0019882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019882", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "vesicle-mediated transport to the plasma membrane", "id": "GO:0098876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098876", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "negative regulation of motile cilium assembly", "id": "GO:1905504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905504", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "myosin V binding", "id": "GO:0031489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031489", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network", "id": "GO:0071782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071782", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "insulin-responsive compartment", "id": "GO:0032593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032593", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "secretory vesicle", "id": "GO:0099503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099503", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-SSC-6798743", "name": "Exocytosis of secretory granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, secretory granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6798743", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798743" } ] }, { "id": "R-SSC-8876188", "name": "DENND4s exchange GTP for GDP on RAB10", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytoplasmic vesicle membrane, cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8876188", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8876188" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 35, "end_pos": 37 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UE23-1", "uniprot_ac": "A0A4X1UE23", "uniprot_id": "A0A4X1UE23_PIG", "mass": { "chemical_mass": 47674.0, "monoisotopic_mass": 47674.0 }, "refseq": {}, "gene_names": [ { "name": "PDIA6", "type": "recommended", "evidence": [ { "id": "A0A4X1UE23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23" } ] } ], "protein_names": [ { "name": "Protein disulfide-isomerase A6", "type": "recommended", "evidence": [ { "id": "A0A4X1UE23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23/entry#names_and_taxonomy" } ] }, { "name": "5.3.4.1", "type": "synonym", "evidence": [ { "id": "A0A4X1UE23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May function as a chaperone that inhibits aggregation of misfolded proteins. Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling. May also regulate the UPR via the EIF2AK3 UPR sensor. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FC46", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FC46#function" }, { "database": "UniProtKB", "id": "ARBA00045396", "url": "https://www.uniprot.org/uniprotkb/ARBA00045396#function" }, { "database": "UniProtKB", "id": "A0A5G2R6R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6R2#function" }, { "database": "UniProtKB", "id": "A0A4X1UE23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23#function" }, { "database": "UniProtKB", "id": "A0A5G2Q895", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q895#function" }, { "database": "UniProtKB", "id": "A0A5G2RA90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA90#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PDIA6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23", "locus": { "chromosome": "3", "start_pos": 125776077, "end_pos": 125751978, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008633", "url": "https://www.ensembl.org/id/ENSSSCG00000008633" } ] } } ], "crossref": [ { "id": "A0A4X1UE23", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UE23", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008633", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008633", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02983", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02983", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03001", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03001", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45815", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45815", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45815:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45815:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24541", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24541", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UE23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UE23-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q895", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q895", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q895-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q895-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6R2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R6R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R6R2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RA90", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RA90-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FC46", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FC46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FC46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FC46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VALGLMSCTLFVAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKVATALKDVVKVGAVDADKHQSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRGGGYSSGKQGRSEGSGKKDVIELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVTRALDLFSDNAPPPELLEIISEDVAKKSCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQTELEHALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPAISTREPWDGKDGELPVEDDIDLSDVELDDLEKDEL", "length": 437, "header": "tr|A0A4X1UE23-1|A0A4X1UE23_PIG Isoform 1 of Protein disulfide-isomerase A6 OS=Sus scrofa OX=9823 GN=PDIA6 PE=1 SV=1 CANONICAL=A0A4X1UE23-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UE23-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23/entry#A0A4X1UE23-1", "sequence": { "sequence": "VALGLMSCTLFVAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKVATALKDVVKVGAVDADKHQSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRGGGYSSGKQGRSEGSGKKDVIELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVTRALDLFSDNAPPPELLEIISEDVAKKSCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQTELEHALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPAISTREPWDGKDGELPVEDDIDLSDVELDDLEKDEL", "length": 437, "header": "tr|A0A4X1UE23-1|A0A4X1UE23_PIG Isoform 1 of Protein disulfide-isomerase A6 OS=Sus scrofa OX=9823 GN=PDIA6 PE=1 SV=1 CANONICAL=A0A4X1UE23-1" }, "locus": { "chromosome": "3", "start_pos": 125774222, "end_pos": 125754294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009445.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009445.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009202.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009202.4" } ] } }, { "isoform_ac": "A0A5G2Q895-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23/entry#A0A5G2Q895-1", "sequence": { "sequence": "MDLGIFFLSLWVNSLSQLNGMVMLRSAALERHLPPPSLALWTGRVDPQARGSVILLVNGPHRPCAPLAHGRVLTQPVLAESVPVEGERVISLPFPQDVVKVGAVDADKHQSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRGGGYSSGKQGRSEGSGKKDVIELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVTRALDLFSDNAPPPELLEIISEDVAKKSCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQTELEHALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPAISTREPWDGKDGELPVEDDIDLSDVELDDLEKDEL", "length": 463, "header": "tr|A0A5G2Q895-1|A0A5G2Q895_PIG Computationally mapped isoform of Protein disulfide-isomerase A6 OS=Sus scrofa OX=9823 GN=PDIA6 PE=1 SV=1 CANONICAL=A0A4X1UE23-1" }, "locus": { "chromosome": "3", "start_pos": 125774222, "end_pos": 125760800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080810.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080810.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060405.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060405.1" } ] } }, { "isoform_ac": "A0A5G2R6R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23/entry#A0A5G2R6R2-1", "sequence": { "sequence": "MARLVLGLMSCTLFVAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKVATALKDVVKVGAVDADKHQSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRGGGYSSGKQGRSEGSGKKDVIELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVTRALDLFSDNAPPPELLEIISEDVAKKSCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQTELEHALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPAISTREPWDGKDGEVSPATREPGDGKDGQASPATREPWDGKDGQASPATREPGDGKDGEASPAEPRGQDASRLWLSFLASLGPEAGCEPGLCIRAAPRAGPAVAPPGPRGLLLSSSSAPLPPATPQAKAPGSCSPGHSPQAERFSTWREAQRGHFEVSLDSRTLPSGLERPTSVAPGVCPRDDGRS", "length": 590, "header": "tr|A0A5G2R6R2-1|A0A4X1UE23_PIG Computationally mapped isoform of Protein disulfide-isomerase A6 OS=Sus scrofa OX=9823 GN=PDIA6 PE=1 SV=2 CANONICAL=A0A4X1UE23-1" }, "locus": { "chromosome": "3", "start_pos": 125773993, "end_pos": 125752079, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076918.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076918.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072769.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072769.2" } ] } }, { "isoform_ac": "A0A5G2RA90-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23/entry#A0A5G2RA90-1", "sequence": { "sequence": "MATLVLCTLFVAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKVATALKDVVKVGAVDADKHQSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRGGGYSSGKQGRSEGSGKKDVIELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVTRALDLFSDNAPPPELLEIISEDVAKKSCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQTELEHALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPAISTREPWDGKDGEVSPATREPGDGKDGQASPATREPWDGKDGQASPATREPGDGKDGEASPAEPRGQDASRLWLSFLASLGPEAGCEPGLCIRAAPRAGPAVAPPGPRGLLLSSSSAPLPPATPQAKAPGSCSPGHSPQAERFSTWREAQRGHFEVSLDSRTLPSGLERPTSVAPGVCPRDDGRS", "length": 586, "header": "tr|A0A5G2RA90-1|A0A4X1UE23_PIG Computationally mapped isoform of Protein disulfide-isomerase A6 OS=Sus scrofa OX=9823 GN=PDIA6 PE=1 SV=2 CANONICAL=A0A4X1UE23-1" }, "locus": { "chromosome": "3", "start_pos": 125773993, "end_pos": 125756443, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074814.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074814.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074234.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074234.2" } ] } }, { "isoform_ac": "A0A8W4FC46-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23/entry#A0A8W4FC46-1", "sequence": { "sequence": "VRRDCTLFVAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKVATALKDVVKVGAVDADKHQSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRGGGYSSGKQGRSEGSGKKDVIELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVTRALDLFSDNAPPPELLEIISEDVAKKSCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQTELEHALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPAISTREPWDGKDGELPVEDDIDLSDVELDDLEKDEL", "length": 434, "header": "tr|A0A8W4FC46-1|A0A4X1UE23_PIG Computationally mapped isoform of Protein disulfide-isomerase A6 OS=Sus scrofa OX=9823 GN=PDIA6 PE=1 SV=1 CANONICAL=A0A4X1UE23-1" }, "locus": { "chromosome": "3", "start_pos": 125774222, "end_pos": 125756649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099202.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099202.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076428.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076428.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FC46", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FC46" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-SSC-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23" } ], "pmid": "" }, { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UE23", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-8952289", "name": "FAM20C phosphorylates FAM20C substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8952289", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8952289" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UE23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UE23" }, { "id": "PS51352", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 130, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UQD7-1", "uniprot_ac": "A0A4X1UQD7", "uniprot_id": "A0A4X1UQD7_PIG", "mass": { "chemical_mass": 35704.0, "monoisotopic_mass": 35704.0 }, "refseq": {}, "gene_names": [ { "name": "SEC13", "type": "recommended", "evidence": [ { "id": "A0A4X1UQD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ] } ], "protein_names": [ { "name": "Protein SEC13 homolog", "type": "recommended", "evidence": [ { "id": "A0A4X1UQD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7/entry#names_and_taxonomy" } ] }, { "name": "GATOR2 complex protein SEC13", "type": "synonym", "evidence": [ { "id": "A0A4X1UQD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7/entry#names_and_taxonomy" } ] }, { "name": "SEC13-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A4X1UQD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIU8#function" }, { "database": "UniProtKB", "id": "ARBA00045501", "url": "https://www.uniprot.org/uniprotkb/ARBA00045501#function" }, { "database": "UniProtKB", "id": "A0A8W4FF27", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF27#function" }, { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7#function" }, { "database": "UniProtKB", "id": "A0A4X1USJ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USJ2#function" }, { "database": "UniProtKB", "id": "A0A5G2R7E5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E5#function" }, { "database": "UniProtKB", "id": "A0A5G2RF34", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF34#function" }, { "database": "UniProtKB", "id": "A0A5G2RJI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJI2#function" }, { "database": "UniProtKB", "id": "F1SQA9", "url": "https://www.uniprot.org/uniprotkb/F1SQA9#function" } ] }, { "annotation": "Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIU8#function" }, { "database": "UniProtKB", "id": "ARBA00055194", "url": "https://www.uniprot.org/uniprotkb/ARBA00055194#function" }, { "database": "UniProtKB", "id": "A0A8W4FF27", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF27#function" }, { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7#function" }, { "database": "UniProtKB", "id": "A0A4X1USJ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USJ2#function" }, { "database": "UniProtKB", "id": "A0A5G2R7E5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E5#function" }, { "database": "UniProtKB", "id": "A0A5G2RF34", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF34#function" }, { "database": "UniProtKB", "id": "A0A5G2RJI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJI2#function" }, { "database": "UniProtKB", "id": "F1SQA9", "url": "https://www.uniprot.org/uniprotkb/F1SQA9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SEC13", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7", "locus": { "chromosome": "13", "start_pos": 66480169, "end_pos": 66524384, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011572", "url": "https://www.ensembl.org/id/ENSSSCG00000011572" } ] } } ], "crossref": [ { "id": "A0A4X1UQD7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UQD7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011572", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011572", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11024:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11024:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-159227", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159227", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-159230", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-159231", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1855170", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1855196", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855196", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1855229", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855229", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-191859", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-191859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2132295", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3232142", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3232142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3301854", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3301854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3371453", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4085377", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4085377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4570464", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4570464", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68877", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9615933", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9615933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983170", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UQD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1USJ2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1USJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7E5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7E5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RF34", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RF34-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJI2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FF27", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FF27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SQA9", "url": "https://www.uniprot.org/uniprotkb/F1SQA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SQA9-1", "url": "https://www.uniprot.org/uniprotkb/F1SQA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GEMVSVINTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHTGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGLGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSTSITEGQQNEQ", "length": 324, "header": "tr|A0A4X1UQD7-1|A0A4X1UQD7_PIG Isoform 1 of Protein SEC13 homolog OS=Sus scrofa OX=9823 GN=SEC13 PE=1 SV=1 CANONICAL=A0A4X1UQD7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UQD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7/entry#A0A4X1UQD7-1", "sequence": { "sequence": "GEMVSVINTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHTGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGLGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSTSITEGQQNEQ", "length": 324, "header": "tr|A0A4X1UQD7-1|A0A4X1UQD7_PIG Isoform 1 of Protein SEC13 homolog OS=Sus scrofa OX=9823 GN=SEC13 PE=1 SV=1 CANONICAL=A0A4X1UQD7-1" }, "locus": { "chromosome": "13", "start_pos": 66522607, "end_pos": 66483981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088448.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088448.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074573.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074573.1" } ] } }, { "isoform_ac": "A0A4X1USJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7/entry#A0A4X1USJ2-1", "sequence": { "sequence": "MHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHTGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGLGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSTSITEGQQNEQ", "length": 307, "header": "tr|A0A4X1USJ2-1|A0A4X1USJ2_PIG Computationally mapped isoform of Protein SEC13 homolog OS=Sus scrofa OX=9823 GN=SEC13 PE=1 SV=1 CANONICAL=A0A4X1UQD7-1" }, "locus": { "chromosome": "13", "start_pos": 66524281, "end_pos": 66483981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088278.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088278.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064632.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064632.1" } ] } }, { "isoform_ac": "A0A5G2R7E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7/entry#A0A5G2R7E5-1", "sequence": { "sequence": "GRVVGVVLNHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHTGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGLGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSTSITEGQQNEQ", "length": 315, "header": "tr|A0A5G2R7E5-1|A0A4X1UQD7_PIG Computationally mapped isoform of Protein SEC13 homolog OS=Sus scrofa OX=9823 GN=SEC13 PE=1 SV=2 CANONICAL=A0A4X1UQD7-1" }, "locus": { "chromosome": "13", "start_pos": 66519454, "end_pos": 66483981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087567.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087567.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073167.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073167.2" } ] } }, { "isoform_ac": "A0A5G2RF34-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7/entry#A0A5G2RF34-1", "sequence": { "sequence": "MSGRLVQTRLSVLVTTPPHTHPRSLQAAPALLPLQHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHTGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGLGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVHTPCIFESSV", "length": 315, "header": "tr|A0A5G2RF34-1|A0A4X1UQD7_PIG Computationally mapped isoform of Protein SEC13 homolog OS=Sus scrofa OX=9823 GN=SEC13 PE=1 SV=2 CANONICAL=A0A4X1UQD7-1" }, "locus": { "chromosome": "13", "start_pos": 66519037, "end_pos": 66493713, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088438.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088438.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073337.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073337.2" } ] } }, { "isoform_ac": "A0A5G2RJI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7/entry#A0A5G2RJI2-1", "sequence": { "sequence": "VSVINTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHTGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGLGQWEVKKINNAHTCPQGPSMLLQMIGCNAVSWAPAVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSTSITEGQQNEQ", "length": 332, "header": "tr|A0A5G2RJI2-1|A0A4X1UQD7_PIG Computationally mapped isoform of Protein SEC13 homolog OS=Sus scrofa OX=9823 GN=SEC13 PE=1 SV=1 CANONICAL=A0A4X1UQD7-1" }, "locus": { "chromosome": "13", "start_pos": 66521143, "end_pos": 66483981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076311.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076311.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072024.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072024.2" } ] } }, { "isoform_ac": "A0A8W4FF27-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7/entry#A0A8W4FF27-1", "sequence": { "sequence": "MSGRLVQTRLSVLVTTPPHTHPRSLQAAPALLPLQHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHTGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGLGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSTSITEGQQNEQ", "length": 341, "header": "tr|A0A8W4FF27-1|A0A4X1UQD7_PIG Computationally mapped isoform of Protein SEC13 homolog OS=Sus scrofa OX=9823 GN=SEC13 PE=1 SV=1 CANONICAL=A0A4X1UQD7-1" }, "locus": { "chromosome": "13", "start_pos": 66519037, "end_pos": 66483981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095584.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095584.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077917.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077917.1" } ] } }, { "isoform_ac": "A0A8W4FIU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7/entry#A0A8W4FIU8-1", "sequence": { "sequence": "MSGRLVQTRLSVLVTTPPHTHPRSLQAAPALLPLQHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHTGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGLGQWEVKKINNAHTVIPSMLLQMIGCNAVSWAPAVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSTSITEGQQNEQ", "length": 350, "header": "tr|A0A8W4FIU8-1|A0A4X1UQD7_PIG Computationally mapped isoform of Protein SEC13 homolog OS=Sus scrofa OX=9823 GN=SEC13 PE=1 SV=1 CANONICAL=A0A4X1UQD7-1" }, "locus": { "chromosome": "13", "start_pos": 66519037, "end_pos": 66483981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106433.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106433.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078809.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078809.1" } ] } }, { "isoform_ac": "F1SQA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7/entry#F1SQA9-1", "sequence": { "sequence": "HDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHTGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGLGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSTSITEGQQNEQ", "length": 306, "header": "tr|F1SQA9-1|F1SQA9_PIG Computationally mapped isoform of Protein SEC13 homolog OS=Sus scrofa OX=9823 GN=SEC13 PE=1 SV=5 CANONICAL=A0A4X1UQD7-1" }, "locus": { "chromosome": "13", "start_pos": 66518932, "end_pos": 66483981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012664.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012664.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012331.5", "url": "https://www.ensembl.org/id/ENSSSCP00000012331.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FF27", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF27" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-SSC-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-SSC-159227", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159227", "resource": "Reactome", "description": "Transport of the SLBP independent Mature mRNA" }, { "id": "R-SSC-159230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159230", "resource": "Reactome", "description": "Transport of the SLBP Dependant Mature mRNA" }, { "id": "R-SSC-159231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159231", "resource": "Reactome", "description": "Transport of Mature mRNA Derived from an Intronless Transcript" }, { "id": "R-SSC-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-SSC-1855170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855170", "resource": "Reactome", "description": "IPs transport between nucleus and cytosol" }, { "id": "R-SSC-1855196", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855196", "resource": "Reactome", "description": "IP3 and IP4 transport between cytosol and nucleus" }, { "id": "R-SSC-1855229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855229", "resource": "Reactome", "description": "IP6 and IP7 transport between cytosol and nucleus" }, { "id": "R-SSC-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-191859", "resource": "Reactome", "description": "snRNP Assembly" }, { "id": "R-SSC-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-SSC-2132295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "resource": "Reactome", "description": "MHC class II antigen presentation" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-SSC-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-SSC-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-SSC-3301854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3301854", "resource": "Reactome", "description": "Nuclear Pore Complex (NPC) Disassembly" }, { "id": "R-SSC-3371453", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "resource": "Reactome", "description": "Regulation of HSF1-mediated heat shock response" }, { "id": "R-SSC-4085377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4085377", "resource": "Reactome", "description": "SUMOylation of SUMOylation proteins" }, { "id": "R-SSC-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-SSC-4570464", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4570464", "resource": "Reactome", "description": "SUMOylation of RNA binding proteins" }, { "id": "R-SSC-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-SSC-68877", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "resource": "Reactome", "description": "Mitotic Prometaphase" }, { "id": "R-SSC-9615933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9615933", "resource": "Reactome", "description": "Postmitotic nuclear pore complex (NPC) reformation" }, { "id": "R-SSC-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" }, { "id": "R-SSC-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" }, { "id": "R-SSC-983170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983170", "resource": "Reactome", "description": "Antigen Presentation: Folding, assembly and peptide loading of class I MHC" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "COPII-coated vesicle cargo loading", "id": "GO:0090110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090110", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "cellular response to nutrient levels", "id": "GO:0031669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031669", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "protein exit from endoplasmic reticulum", "id": "GO:0032527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032527", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "positive regulation of TOR signaling", "id": "GO:0032008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032008", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "COPII-coated vesicle budding", "id": "GO:0090114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090114", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nuclear pore outer ring", "id": "GO:0031080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031080", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "GATOR2 complex", "id": "GO:0061700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061700", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQD7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1V2P7-1", "uniprot_ac": "A0A4X1V2P7", "uniprot_id": "A0A4X1V2P7_PIG", "mass": { "chemical_mass": 23903.0, "monoisotopic_mass": 23903.0 }, "refseq": { "ac": "NP_001038011", "name": "inducible T-cell costimulator precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038011" }, "gene_names": [ { "name": "ICOS", "type": "recommended", "evidence": [ { "id": "A0A4X1V2P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7" } ] }, { "name": "ICOS", "type": "synonym", "evidence": [ { "id": "NP_001038011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038011" } ] } ], "protein_names": [ { "name": "Inducible T-cell costimulator", "type": "recommended", "evidence": [ { "id": "A0A4X1V2P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7/entry#names_and_taxonomy" } ] }, { "name": "inducible T-cell co-stimulator", "type": "synonym", "evidence": [ { "id": "NP_001038011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038011" } ] }, { "name": "inducible T-cell costimulator precursor", "type": "synonym", "evidence": [ { "id": "NP_001038011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038011" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V2P7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ICOS", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7", "locus": { "chromosome": "15", "start_pos": 107370119, "end_pos": 107350203, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000025042", "url": "https://www.ensembl.org/id/ENSSSCG00000025042" } ] } } ], "crossref": [ { "id": "A0A4X1V2P7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1V2P7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000025042", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000025042", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "733597", "url": "https://www.ncbi.nlm.nih.gov/gene/733597", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:733597", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:733597", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDKEDCF", "url": "https://omabrowser.org/oma/group/QDKEDCF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1V2P7", "url": "https://www.orthodb.org/?gene=A0A4X1V2P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20904", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20904", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20904:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20904:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15910", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15910", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1257604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6811558", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9927354", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9927354", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001038011", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038011", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A7M9", "url": "https://www.uniprot.org/uniprotkb/A0A287A7M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A7M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A7M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V2P7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V2P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSDLWYFFLFCFQVEVLMGEVNDSAKSEMFMFHDGGLQIVCKYPDTVRQFKMQLLKGKNILCDLTKTKGSGNTVSITNVNLCQFQLSNNSVSFFLYNLDSSYASYYICELSIFDPPPFQVDILSKEYLNIYESQLCCQLKFWLLLGCAAFVVVYIIGCVLTCWLTKKKYRPSVHDPNSEYMFMAAVNTTKKAGPTDVTRNLVRSGTRA", "length": 209, "header": "tr|A0A4X1V2P7-1|A0A4X1V2P7_PIG Isoform 1 of Inducible T-cell costimulator OS=Sus scrofa OX=9823 GN=ICOS PE=4 SV=1 CANONICAL=A0A4X1V2P7-1" }, "isoforms": [ { "isoform_ac": "A0A287A7M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7/entry#A0A287A7M9-1", "sequence": { "sequence": "MKSDLWYFFLFCFQVEVLMGEVNDSAKSEMFMFHDGGLQIVCKYPDTVRQFKMQLLKGKNILCDLTKTKGSGNTVSITNVNLCQFQLSNNSVSFFLYNLDSSYASYYICELSIFDPPPFQVDILSKEYLNIYESQLCCQLKFWLLLGCAAFVVVYIIGCVLTCWLTKKM", "length": 169, "header": "tr|A0A287A7M9-1|A0A4X1V2P7_PIG Computationally mapped isoform of Inducible T-cell costimulator OS=Sus scrofa OX=9823 GN=ICOS PE=4 SV=2 CANONICAL=A0A4X1V2P7-1" }, "locus": { "chromosome": "15", "start_pos": 107368137, "end_pos": 107350288, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062649.2", "url": "https://www.ensembl.org/id/ENSSSCT00000062649.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039773.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039773.2" } ] } }, { "isoform_ac": "A0A4X1V2P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7/entry#A0A4X1V2P7-1", "sequence": { "sequence": "MKSDLWYFFLFCFQVEVLMGEVNDSAKSEMFMFHDGGLQIVCKYPDTVRQFKMQLLKGKNILCDLTKTKGSGNTVSITNVNLCQFQLSNNSVSFFLYNLDSSYASYYICELSIFDPPPFQVDILSKEYLNIYESQLCCQLKFWLLLGCAAFVVVYIIGCVLTCWLTKKKYRPSVHDPNSEYMFMAAVNTTKKAGPTDVTRNLVRSGTRA", "length": 209, "header": "tr|A0A4X1V2P7-1|A0A4X1V2P7_PIG Isoform 1 of Inducible T-cell costimulator OS=Sus scrofa OX=9823 GN=ICOS PE=4 SV=1 CANONICAL=A0A4X1V2P7-1" }, "locus": { "chromosome": "15", "start_pos": 107368172, "end_pos": 107350288, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024007.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024007.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028023.3", "url": "https://www.ensembl.org/id/ENSSSCP00000028023.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 196, "start_aa": "Thr", "end_pos": 196, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr196", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A7M9", "url": "https://www.uniprot.org/uniprotkb/A0A287A7M9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:733597", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:733597", "resource": "KEGG Pathway" }, { "id": "R-SSC-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-SSC-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" }, { "id": "R-SSC-9927354", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9927354", "resource": "Reactome", "description": "Co-stimulation by ICOS" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZTP5-1", "protein_name": "Inducible T-cell costimulator", "gene_name": "ICOS", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNESFLQPGSVLPPTSRTGTERSLLHYWISAATWSSATSLDVGSLATSSKQAHTYFRRLMPLCQASMKTVAVTFCLLCFQFEALCGVDTCSSRLCKNIDKLQVSDPQGIVEFENGNFKLIFQNPKNVNEFSMTLLKGRERKAICALHMNNKKAVPESNVTYCQAEHSDTSTTFILTNLDRKHIDTYTCCLESLLPPPYIHCHLKETYLYIQDKEDCSSQGIMSWIIIGLIAFALIFCVCFVVACHLRNKNQQCESNSHEYNSEYMPMAAVNAAKKPRI", "length": 278 }, "evidence": [ { "id": "A0A4X1V2P7", "url": "https://omabrowser.org/oma/group/A0A4X1V2P7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q58DF9-1", "protein_name": "Inducible T-cell costimulator", "gene_name": "ICOS", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKSDLRYFFLFCIQVEILAGEFNDSAASEMFIFHNGGVQILCKYPDTVRQFKMQLLKGDNVLCDLTKTKENEDTVSIRNLNVCKFQLSNNSVSFFLYNLDSSYASYYICKLSIFDPPPFQVDILSREYLNIYESELCCQLKFWLPIGCAAFVTVCVFGCVLMYWLTKKKYPTSVHDPNSEYMFMAAVNTAKKPAPTDVTRNLELPGTQA", "length": 209 }, "evidence": [ { "id": "A0A4X1V2P7", "url": "https://omabrowser.org/oma/group/A0A4X1V2P7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9R1T7-1", "protein_name": "Inducible T-cell costimulator", "gene_name": "Icos", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPYFSCVFVFCFLIKLLTGELNDLANHRMFSFHDGGVQISCNYPETVQQLKMQLFKDREVLCDLTKTKGSGNTVSIKNPMSCPYQLSNNSVSFFLDNADSSQGSYFLCSLSIFDPPPFQEKNLSGGYLLIYESQLCCQLKLWLPVGCAAFVAALLFGCIFIVWFAKKKYRSSVHDPNSEYMFMAAVNTNKKSRLAGMTS", "length": 200 }, "evidence": [ { "id": "A0A4X1V2P7", "url": "https://omabrowser.org/oma/group/A0A4X1V2P7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WVS0-1", "protein_name": "Inducible T-cell costimulator", "gene_name": "Icos", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPYFCRVFVFCFLIRLLTGEINGSADHRMFSFHNGGVQISCKYPETVQQLKMRLFREREVLCELTKTKGSGNAVSIKNPMLCLYHLSNNSVSFFLNNPDSSQGSYYFCSLSIFDPPPFQERNLSGGYLHIYESQLCCQLKLWLPVGCAAFVVVLLFGCILIIWFSKKKYGSSVHDPNSEYMFMAAVNTNKKSRLAGVTS", "length": 200 }, "evidence": [ { "id": "A0A4X1V2P7", "url": "https://omabrowser.org/oma/group/A0A4X1V2P7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6W8-1", "protein_name": "Inducible T-cell costimulator", "gene_name": "ICOS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSGLWYFFLFCLRIKVLTGEINGSANYEMFIFHNGGVQILCKYPDIVQQFKMQLLKGGQILCDLTKTKGSGNTVSIKSLKFCHSQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPFKVTLTGGYLHIYESQLCCQLKFWLPIGCAAFVVVCILGCILICWLTKKKYSSSVHDPNGEYMFMRAVNTAKKSRLTDVTL", "length": 199 }, "evidence": [ { "id": "A0A4X1V2P7", "url": "https://omabrowser.org/oma/group/A0A4X1V2P7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V2P7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "T cell costimulation", "id": "GO:0031295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031295", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V2P7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V2P7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7" } ], "pmid": "" }, { "name": "T cell tolerance induction", "id": "GO:0002517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002517", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V2P7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7" } ], "pmid": "" }, { "name": "T follicular helper cell differentiation", "id": "GO:0061470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061470", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V2P7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V2P7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1V2P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V2P7" }, { "id": "PF15910", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15910" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Immunoglobulin V-set", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 135, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 196 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 }, { "start_pos": 23, "end_pos": 25 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VTU2-1", "uniprot_ac": "A0A4X1VTU2", "uniprot_id": "A0A4X1VTU2_PIG", "mass": { "chemical_mass": 38266.0, "monoisotopic_mass": 38266.0 }, "refseq": { "ac": "XP_003356250", "name": "UDP-glucose 4-epimerase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003356250" }, "gene_names": [ { "name": "GALE", "type": "recommended", "evidence": [ { "id": "A0A4X1VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2" } ] }, { "name": "GALE", "type": "synonym", "evidence": [ { "id": "XP_003356250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003356250" } ] } ], "protein_names": [ { "name": "UDP-glucose 4-epimerase", "type": "recommended", "evidence": [ { "id": "A0A4X1VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2/entry#names_and_taxonomy" } ] }, { "name": "5.1.3.2", "type": "synonym", "evidence": [ { "id": "A0A4X1VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2/entry#names_and_taxonomy" } ] }, { "name": "UDP-glucose 4-epimerase", "type": "synonym", "evidence": [ { "id": "XP_003356250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003356250" } ] } ], "function": [ { "annotation": "Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A8P8", "url": "https://www.uniprot.org/uniprotkb/A0A287A8P8#function" }, { "database": "UniProtKB", "id": "ARBA00002760", "url": "https://www.uniprot.org/uniprotkb/ARBA00002760#function" }, { "database": "UniProtKB", "id": "A0A4X1VTU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VTU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GALE", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2", "locus": { "chromosome": "6", "start_pos": 81605968, "end_pos": 81610473, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027827", "url": "https://www.ensembl.org/id/ENSSSCG00000027827" } ] } } ], "crossref": [ { "id": "ENSSSCG00000027827", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027827", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05247", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05247", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100621392", "url": "https://www.ncbi.nlm.nih.gov/gene/100621392", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621392", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621392", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GEHLICN", "url": "https://omabrowser.org/oma/group/GEHLICN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1VTU2", "url": "https://www.orthodb.org/?gene=A0A4X1VTU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43725", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43725", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43725:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43725:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-70370", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70370", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003356250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003356250", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20517", "url": "https://www.rhea-db.org/rhea/20517", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "22168", "url": "https://www.rhea-db.org/rhea/22168", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A8P8", "url": "https://www.uniprot.org/uniprotkb/A0A287A8P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A8P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A8P8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VTU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VTU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VZM2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VZM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VZM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VZM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEKVLVTGGAGYIGSHTVLELLEAGYSPVVIDNFHNAIRGGSSMPESLRRVQELTGRSVEFEEMDILDQAALQRLFKKYHFVAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKAWNAVLLRYFNPIGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVRAMEKASGKKIPYKVVARREGDVAACYANPSLALKELGWTAALGLDRMCEDLWRWQKQNPSGFGAQA", "length": 348, "header": "tr|A0A4X1VTU2-1|A0A4X1VTU2_PIG Isoform 1 of UDP-glucose 4-epimerase OS=Sus scrofa OX=9823 GN=GALE PE=1 SV=1 CANONICAL=A0A4X1VTU2-1" }, "isoforms": [ { "isoform_ac": "A0A287A8P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2/entry#A0A287A8P8-1", "sequence": { "sequence": "MAEKVLVTGGAGYIGSHTVLELLEAGYSPVVIDNFHNAIRGGSSMPESLRRVQELTGRSVEFEEMDILDQAALQRLFKKYHFVAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKVAIGRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVRAMEKASGKKIPYKVVARREGDVAACYANPSLALKELGWTAALGLDRMCEDLWRWQKQNPSGFGAQA", "length": 310, "header": "tr|A0A287A8P8-1|A0A4X1VTU2_PIG Computationally mapped isoform of UDP-glucose 4-epimerase OS=Sus scrofa OX=9823 GN=GALE PE=1 SV=1 CANONICAL=A0A4X1VTU2-1" }, "locus": { "chromosome": "6", "start_pos": 81608756, "end_pos": 81606294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043433.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043433.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040188.1", "url": "https://www.ensembl.org/id/ENSSSCP00000040188.1" } ] } }, { "isoform_ac": "A0A4X1VTU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2/entry#A0A4X1VTU2-1", "sequence": { "sequence": "MAEKVLVTGGAGYIGSHTVLELLEAGYSPVVIDNFHNAIRGGSSMPESLRRVQELTGRSVEFEEMDILDQAALQRLFKKYHFVAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKAWNAVLLRYFNPIGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVRAMEKASGKKIPYKVVARREGDVAACYANPSLALKELGWTAALGLDRMCEDLWRWQKQNPSGFGAQA", "length": 348, "header": "tr|A0A4X1VTU2-1|A0A4X1VTU2_PIG Isoform 1 of UDP-glucose 4-epimerase OS=Sus scrofa OX=9823 GN=GALE PE=1 SV=1 CANONICAL=A0A4X1VTU2-1" }, "locus": { "chromosome": "6", "start_pos": 81608756, "end_pos": 81606294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028713.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028713.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024851.3", "url": "https://www.ensembl.org/id/ENSSSCP00000024851.3" } ] } }, { "isoform_ac": "A0A4X1VZM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2/entry#A0A4X1VZM2-1", "sequence": { "sequence": "MAEKVLVTGGAGYIGSHTVLELLEAGYSPVVIDNFHNAIRGGSSMPESLRRVQELTGRSVEFEEMDILDQAALQRLFKKYHFVAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKAWNAVLLRYFNPIGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVRAMEKASGKKVKIYGAGRSRILQALVHRPEILWGQKRKRNKCLLSSLRHEPWGLRASPTSDPSWAHLAHQARGQGPH", "length": 358, "header": "tr|A0A4X1VZM2-1|A0A4X1VZM2_PIG Computationally mapped isoform of UDP-glucose 4-epimerase OS=Sus scrofa OX=9823 GN=GALE PE=1 SV=1 CANONICAL=A0A4X1VTU2-1" }, "locus": { "chromosome": "6", "start_pos": 81608756, "end_pos": 81606149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058934.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058934.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056308.1", "url": "https://www.ensembl.org/id/ENSSSCP00000056308.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A8P8", "url": "https://www.uniprot.org/uniprotkb/A0A287A8P8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621392", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621392", "resource": "KEGG Pathway" }, { "id": "R-SSC-70370", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70370", "resource": "Reactome", "description": "Galactose catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7K2W2-1", "protein_name": "UDP-glucose 4-epimerase", "gene_name": "Gale", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFSSAQDCPFSRQGGAMAEKVLVTGGAGYIGSHTVLELLEAGYAPVVIDNFHNAIRGGDSMPESLRRVQELTGRSVEFEEMDILDQAALQHLFKKHSFKAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMRAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMVRDLCRADSAWNAVLLRYFNPTGAHASGRIGEDPQGVPNNLMPYVSQVAIGRREALNVFGGDYDTEDGTGVRDYIHVVDLAKGHIAALKKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAHEELGWTAALGLDRMCEDLWRWQKQNPSGFGAQA", "length": 364 }, "evidence": [ { "id": "A0A4X1VTU2", "url": "https://omabrowser.org/oma/group/A0A4X1VTU2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1Q5H4-1", "protein_name": "UDP-glucose 4-epimerase", "gene_name": "gale", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRQKILVTGGGGYIGSHCVVELIEAGFHPVVIDNFSNAVRGEGDVPESLRRIEKFMDTQIEFHELDLLDKPGLEKIFKMHSFYAVMHFAGLKAVGESVEQPLRYYRVNLTGTINLLEVMQSHGVRNLVFSSSATVYGDPQKLPIDEQHPVGGCTNPYGKTKYFIEEMIRDQCTAEKDWNAVLLRYFNPIGAHISGQIGEDPQGIPNNLLPYVAQVAIGRRKHLNVFGNDYSTPDGTGVRDYIHVVDLAKGHIAAVRKLKDSCGCKVYNLGTGTGYSVLQMVSAMEKASGRKIAYQIAPRRSGDVASCYADASLAEKELGWKAEFDLERMCEDLWRWQSQNPTGFSNGTLP", "length": 350 }, "evidence": [ { "id": "A0A4X1VTU2", "url": "https://omabrowser.org/oma/group/A0A4X1VTU2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P18645-1", "protein_name": "UDP-glucose 4-epimerase", "gene_name": "Gale", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEKVLVTGGAGYIGSHTVLELLEAGYSPVVIDNFHNSIRGEDSMPESLRRVQELTGRSVEFEEMDILDQAALQHLFKKHNFKAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMRAMGVKSLVFSSSATVYGKPVPASGRGPPHRGCTKPYGKSKFFIEEMIQDLCRADTAWNAVLLRYFIPIGAHRSARIGEDPQGIPNNLMPYVSQVAIGRREALNVFGDDYATEDGTGVRDYIHVVDLAKGHIAALKKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAHEELGWTAALGLDRMCEDLWRWQKQNPSGLGAHG", "length": 347 }, "evidence": [ { "id": "A0A4X1VTU2", "url": "https://omabrowser.org/oma/group/A0A4X1VTU2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14376-1", "protein_name": "UDP-glucose 4-epimerase", "gene_name": "GALE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA", "length": 348 }, "evidence": [ { "id": "A0A4X1VTU2", "url": "https://omabrowser.org/oma/group/A0A4X1VTU2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3EAY3-1", "protein_name": "UDP-glucose 4-epimerase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MCRDLWNWASNNPYGYNSSSNGSSS", "length": 25 }, "evidence": [ { "id": "A0A4X1VTU2", "url": "https://omabrowser.org/oma/group/A0A4X1VTU2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q553X7-1", "protein_name": "UDP-glucose 4-epimerase", "gene_name": "galE", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPIDDRIMVTGGAGYIGSHTVIELIEAGYTPVIVDNLSNSSLEAIKRVESITGKEIEFHHVDIMNEKALDEIFETGNIRSVIHFAGLKAVGESNKLPLKYYNNNIAGTLTLLNLMDKHRVKKLVFSSSATVYGDPHTVPITEDFPLSATNPYGRTKLYVEGILQDLCASDPEWNCIMLRYFNPVGAHPSGLIGEDPKDIPNNLMPYVTQTAIGKRPILSIFGNDYNTPDGTGVRDFIHVVDLAKGHISALSSLHSKKQGCVAYNLGTGRGYSVLEMVGALKQASHKEIPYQIVSRRKGDVASSFADPSKALKELGWKATHNQDDMCRDAWKWQSLNPNGYSDS", "length": 344 }, "evidence": [ { "id": "A0A4X1VTU2", "url": "https://omabrowser.org/oma/group/A0A4X1VTU2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8R059-1", "protein_name": "UDP-glucose 4-epimerase", "gene_name": "Gale", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVLVTGGAGYIGSHTVLELLEAGYSPVVIDNFHNAIRGEDSMPESLRRVQELTGRSVEFEEMDILDQAALQHLFKKHSFKAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMRAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCRADTAWNAVLLRYFNPIGAHASGRIGEDPQGIPNNLMPYVSQVAIGRREALNVFGDDYATEDGTGVRDYIHVVDLAKGHIAALKKLKEQCGCRTYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAHEELGWTAALGLDRMCEDLWRWQKQNPSGFGAQA", "length": 347 }, "evidence": [ { "id": "A0A4X1VTU2", "url": "https://omabrowser.org/oma/group/A0A4X1VTU2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9T0A7-1", "protein_name": "UDP-glucose 4-epimerase 2", "gene_name": "UGE2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAKSVLVTGGAGYIGSHTVLQLLEGGYSAVVVDNYDNSSAASLQRVKKLAGENGNRLSFHQVDLRDRPALEKIFSETKFDAVIHFAGLKAVGESVEKPLLYYNNNIVGTVTLLEVMAQYGCKNLVFSSSATVYGWPKEVPCTEESPISATNPYGRTKLFIEEICRDVHRSDSEWKIILLRYFNPVGAHPSGYIGEDPLGVPNNLMPYVQQVAVGRRPHLTVFGTDYKTKDGTGVRDYIHVMDLADGHIAALRKLDDLKISCEVYNLGTGNGTSVLEMVAAFEKASGKKIPLVMAGRRPGDAEVVYASTEKAERELNWKAKNGIEEMCRDLWNWASNNPYGYNSSSNGSSS", "length": 350 }, "evidence": [ { "id": "A0A4X1VTU2", "url": "https://omabrowser.org/oma/group/A0A4X1VTU2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W0P5-1", "protein_name": "UDP-glucose 4-epimerase", "gene_name": "Gale", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAPPTVLVTGGAGYIGSHTVLEMLNAGYNVICVDNLCNAYSSGAKLPEALSRVQEITGKKVNFYRVDITDREQVRSVFQEHKIDMVAHFAALKAVGESCRIPLQYYHNNMTGTNVLLEAMADNNVFKFVYSSSATVYGEPKFLPVTEEHPTGNCTSPYGKTKYFTEEILKDLCKSDKRWAVVSLRYFNPVGAHISGRIGEDPNGEPNNLMPYIAQVAVGRRPSLSVYGSDFPTHDGTGVRDYIHIVDLAEGHVKALDKLRNIAETGFFAYNLGTGVGYSVLDMVKAFEKASGKKVNYTLVDRRSGDVATCYADATLADKKLGWKAERGIDKMCEDTWRWQSQNPNGYANK", "length": 350 }, "evidence": [ { "id": "A0A4X1VTU2", "url": "https://omabrowser.org/oma/group/A0A4X1VTU2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "UDP-glucose 4-epimerase activity", "id": "GO:0003978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VTU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine 4-epimerase activity", "id": "GO:0003974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003974", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VTU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VTU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "galactose metabolic process", "id": "GO:0006012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006012", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VTU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2" } ], "pmid": "" }, { "name": "galactose catabolic process via UDP-galactose, Leloir pathway", "id": "GO:0033499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033499", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VTU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VTU2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20517", "name": "", "equation": "UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20517", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20517" } ] }, { "id": "22168", "name": "", "equation": "UDP-alpha-D-glucose = UDP-alpha-D-galactose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "22168", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22168" } ] }, { "id": "R-SSC-70369", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-70369", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70369" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTU2" }, { "id": "PF16363", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16363" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NAD(P)-binding", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 332, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UH68-1", "uniprot_ac": "A0A4X1UH68", "uniprot_id": "A0A4X1UH68_PIG", "mass": { "chemical_mass": 81953.0, "monoisotopic_mass": 81953.0 }, "refseq": {}, "gene_names": [ { "name": "SLC44A5", "type": "recommended", "evidence": [ { "id": "A0A4X1UH68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68" } ] } ], "protein_names": [ { "name": "Choline transporter-like protein", "type": "recommended", "evidence": [ { "id": "A0A4X1UH68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Choline transporter.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ABL1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABL1#function" }, { "database": "UniProtKB", "id": "RU368066", "url": "https://www.uniprot.org/uniprotkb/RU368066#function" }, { "database": "UniProtKB", "id": "A0A4X1UH68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68#function" } ] }, { "annotation": "Choline/H+ antiporter.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ABL1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABL1#function" }, { "database": "UniProtKB", "id": "ARBA00037726", "url": "https://www.uniprot.org/uniprotkb/ARBA00037726#function" }, { "database": "UniProtKB", "id": "A0A4X1UH68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UH68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC44A5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68", "locus": { "chromosome": "6", "start_pos": 138009865, "end_pos": 137682312, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003777", "url": "https://www.ensembl.org/id/ENSSSCG00000003777" } ] } } ], "crossref": [ { "id": "A0A4X1UH68", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UH68", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003777", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003777", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12385", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12385", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12385:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12385:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1483191", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483191", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9958517", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9958517", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "75463", "url": "https://www.rhea-db.org/rhea/75463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287ABL1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ABL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UH68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UH68-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDEGLPPPYLEGKNYGEPRICDSDFKGPVVNRNCTDVLCCMIFILFIIGYILLGLVAWVNGDPRRVAYPTDSQGHFCGQKDTPNENKTILFYFNLLSCTSPSVVLNLQCPTTQICVSKCPEKFLTYMEIQYMYRKDNSYLTYYSQFCKSAFVKPAKTLTQVLLDNDCPTAIFPSKPFLRRCFPDFSTKNGTLTVGNKTEFEDGSGRRRNAVELRAAANGINKALDARAIGMKVFEDYATTWYWILIGLTIAMFLSWMFVVLLRFTAGFLFWIFTFGVIGIIAYGIWNCYQEYNSLQEKPNSHLTIYHIGVQTDISMYFQLRQTWFILMIILCILEVFVILVLIFLRNRIRISIALLKEGSKAIGYIPTTLIYPVLTFIFLSICISYWAVIAVYLATSGVPVYKVITPKGQCIHENKTCDPQTFNTTEIAKACPGAQCNFAFYGGKSLYHQYITTFQIFNLFVFLWLINFVIALGQCALAGAFASYYWALKKPDDIPPYPLFTAFGRAIRYHTGSLAFGSLILAGIQMFRLILEYLDKRLKEAQNNISKFLKCCLRCCFWCLEKAVKFLNRNAYIMIAIYGKNFCRSAKDAFNLLMRNILKVAVMDRVTDFVLVLGKILVAGCIGVLAFLLFTERLPMIIEGPTSLNYYWVPLLTVIIGSYLIAHGFFSIYAMCIETIFICFCEDLERNDGSTEKPYFIAPTLHGILNKKQLVPQKQKE", "length": 719, "header": "tr|A0A4X1UH68-1|A0A4X1UH68_PIG Isoform 1 of Choline transporter-like protein OS=Sus scrofa OX=9823 GN=SLC44A5 PE=3 SV=1 CANONICAL=A0A4X1UH68-1" }, "isoforms": [ { "isoform_ac": "A0A287ABL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68/entry#A0A287ABL1-1", "sequence": { "sequence": "MSDEGLPPPYLEGKNYGEPRICDSDFKGPVVNRNCTDVLCCMIFILFIIGYILLGLVAWVNGDPRRVAYPTDSQGHFCGQKDTPNENKTILFYFNLLSCTSPSVVLNLQCPTTQICVSKCPEKFLTYMEIQYMYRKDNSYLTYYSQFCKSAFVKPAKTLTQVLLDNDCPTAIFPSKPFLRRCFPDFSTKNGTLTVGNKTEFEDGSGRRRNAVELRAAANGINKALDARAIGMKVFEDYATTWYWILIGLTIAMFLSWMFVVLLRFTAGFLFWIFTFGVIGIIAYGIWNCYQEYNSLQEKPNSHLTIYHIGVQTDISMYFQLRQTWFILMIILCILEVFVILVLIFLRNRIRISIALLKEGSKAIGYIPTTLIYPVLTFIFLSICISYWAVIAVYLATSGVPVYKVITPKGQCIHENKTCDPQTFNTTEIAKACPGAQCNFAFYGGKSLYHQYITTFQIFNLFVFLWLINFVIALGQCALAGAFASYYWALKKPDDIPPYPLFTAFGRAIRYHTGSLAFGSLILAGIQMFRLILEYLDKRLKEAQNNISKFLKCCLRCCFWCLEKAVKFLNRNAYIMIAIYGKNFCRSAKDAFNLLMRNILKVAVMDRVTDFVLVLGKILVAGCIGVLAFLLFTERLPMIIEGPTSLNYYWVPLLTVIIGSYLIAHGFFSIYAMCIETIFICFLEDLERNDGSTERPYYMSQSLLKILKEPNVQTKKR", "length": 717, "header": "tr|A0A287ABL1-1|A0A4X1UH68_PIG Computationally mapped isoform of Choline transporter-like protein OS=Sus scrofa OX=9823 GN=SLC44A5 PE=3 SV=2 CANONICAL=A0A4X1UH68-1" }, "locus": { "chromosome": "6", "start_pos": 138008861, "end_pos": 137682312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043528.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043528.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041279.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041279.2" } ] } }, { "isoform_ac": "A0A4X1UH68-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68/entry#A0A4X1UH68-1", "sequence": { "sequence": "MSDEGLPPPYLEGKNYGEPRICDSDFKGPVVNRNCTDVLCCMIFILFIIGYILLGLVAWVNGDPRRVAYPTDSQGHFCGQKDTPNENKTILFYFNLLSCTSPSVVLNLQCPTTQICVSKCPEKFLTYMEIQYMYRKDNSYLTYYSQFCKSAFVKPAKTLTQVLLDNDCPTAIFPSKPFLRRCFPDFSTKNGTLTVGNKTEFEDGSGRRRNAVELRAAANGINKALDARAIGMKVFEDYATTWYWILIGLTIAMFLSWMFVVLLRFTAGFLFWIFTFGVIGIIAYGIWNCYQEYNSLQEKPNSHLTIYHIGVQTDISMYFQLRQTWFILMIILCILEVFVILVLIFLRNRIRISIALLKEGSKAIGYIPTTLIYPVLTFIFLSICISYWAVIAVYLATSGVPVYKVITPKGQCIHENKTCDPQTFNTTEIAKACPGAQCNFAFYGGKSLYHQYITTFQIFNLFVFLWLINFVIALGQCALAGAFASYYWALKKPDDIPPYPLFTAFGRAIRYHTGSLAFGSLILAGIQMFRLILEYLDKRLKEAQNNISKFLKCCLRCCFWCLEKAVKFLNRNAYIMIAIYGKNFCRSAKDAFNLLMRNILKVAVMDRVTDFVLVLGKILVAGCIGVLAFLLFTERLPMIIEGPTSLNYYWVPLLTVIIGSYLIAHGFFSIYAMCIETIFICFCEDLERNDGSTEKPYFIAPTLHGILNKKQLVPQKQKE", "length": 719, "header": "tr|A0A4X1UH68-1|A0A4X1UH68_PIG Isoform 1 of Choline transporter-like protein OS=Sus scrofa OX=9823 GN=SLC44A5 PE=3 SV=1 CANONICAL=A0A4X1UH68-1" }, "locus": { "chromosome": "6", "start_pos": 138005756, "end_pos": 137682312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082903.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082903.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070833.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070833.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ABL1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABL1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1483191", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483191", "resource": "Reactome", "description": "Synthesis of PC" }, { "id": "R-SSC-9958517", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9958517", "resource": "Reactome", "description": "SLC-mediated bile acid transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "organic cation transport", "id": "GO:0015695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015695", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UH68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UH68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UH68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UH68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UH68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UH68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68" } ], "pmid": "" }, { "name": "choline transmembrane transporter activity", "id": "GO:0015220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015220", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UH68", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UH68" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 546, "end_pos": 548, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "75463", "name": "", "equation": "choline(out) + n H(+)(in) = choline(in) + n H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "75463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/75463" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 416, "end_pos": 418 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 546, "end_pos": 548 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VG74-1", "uniprot_ac": "A0A4X1VG74", "uniprot_id": "A0A4X1VG74_PIG", "mass": { "chemical_mass": 15374.0, "monoisotopic_mass": 15374.0 }, "refseq": { "ac": "XP_003353837", "name": "peptidyl-prolyl cis-trans isomerase FKBP2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353837" }, "gene_names": [ { "name": "FKBP2", "type": "recommended", "evidence": [ { "id": "A0A4X1VG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74" } ] }, { "name": "FKBP2", "type": "synonym", "evidence": [ { "id": "XP_003353837", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353837" } ] } ], "protein_names": [ { "name": "peptidylprolyl isomerase", "type": "recommended", "evidence": [ { "id": "A0A4X1VG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74/entry#names_and_taxonomy" } ] }, { "name": "5.2.1.8", "type": "synonym", "evidence": [ { "id": "A0A4X1VG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74/entry#names_and_taxonomy" } ] }, { "name": "peptidyl-prolyl cis-trans isomerase FKBP2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003353837", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353837" } ] } ], "function": [ { "annotation": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ACX4", "url": "https://www.uniprot.org/uniprotkb/A0A287ACX4#function" }, { "database": "UniProtKB", "id": "ARBA00002388", "url": "https://www.uniprot.org/uniprotkb/ARBA00002388#function" }, { "database": "UniProtKB", "id": "A0A4X1VG74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VG74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FKBP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74", "locus": { "chromosome": "2", "start_pos": 7868230, "end_pos": 7871097, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000033757", "url": "https://www.ensembl.org/id/ENSSSCG00000033757" } ] } } ], "crossref": [ { "id": "A0A4X1VG74", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1VG74", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000033757", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033757", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100522180", "url": "https://www.ncbi.nlm.nih.gov/gene/100522180", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522180", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522180", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VHMHYTG", "url": "https://omabrowser.org/oma/group/VHMHYTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287ACX4", "url": "https://www.orthodb.org/?gene=A0A287ACX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1VG74", "url": "https://www.orthodb.org/?gene=A0A4X1VG74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45779", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45779", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45779:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45779:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00254", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00254", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003353837", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353837", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287ACX4", "url": "https://www.uniprot.org/uniprotkb/A0A287ACX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ACX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ACX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VG74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VG74-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLSWVLTVLSICLSALVTATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRSEL", "length": 140, "header": "tr|A0A4X1VG74-1|A0A4X1VG74_PIG Isoform 1 of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=FKBP2 PE=1 SV=1 CANONICAL=A0A4X1VG74-1" }, "isoforms": [ { "isoform_ac": "A0A287ACX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74/entry#A0A287ACX4-1", "sequence": { "sequence": "MTRLRRDGSTTGVDSGGAARRDMRLSWVLTVLSICLSALVTATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRSEL", "length": 162, "header": "tr|A0A287ACX4-1|A0A4X1VG74_PIG Computationally mapped isoform of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=FKBP2 PE=1 SV=2 CANONICAL=A0A4X1VG74-1" }, "locus": { "chromosome": "2", "start_pos": 7871093, "end_pos": 7868309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048189.2", "url": "https://www.ensembl.org/id/ENSSSCT00000048189.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041827.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041827.2" } ] } }, { "isoform_ac": "A0A4X1VG74-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74/entry#A0A4X1VG74-1", "sequence": { "sequence": "MRLSWVLTVLSICLSALVTATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRSEL", "length": 140, "header": "tr|A0A4X1VG74-1|A0A4X1VG74_PIG Isoform 1 of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=FKBP2 PE=1 SV=1 CANONICAL=A0A4X1VG74-1" }, "locus": { "chromosome": "2", "start_pos": 7869782, "end_pos": 7868309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062858.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062858.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040667.1", "url": "https://www.ensembl.org/id/ENSSSCP00000040667.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ACX4", "url": "https://www.uniprot.org/uniprotkb/A0A287ACX4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522180", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522180", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GU62-1", "protein_name": "peptidylprolyl isomerase", "gene_name": "Fkbp2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRGVHVGAVSVVAAPGVAVDRELPLERLCGWSGLGVPLTRAQSGCPGGPRELRAGGAPLVVGARGRDGVCLRRTGAPQSRLAETCGCLGAGHLRQPQRCGCAGQEAAGCGGSGVAQSGLLRCNQIGFGLCVKGLAGTEWKWGPGGREGLVLSKGAGPWLLWPPLSPSPRCWGPRPSPLLTGLVGCAYRDMRLSRVLTILSICLSALATAKGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFTLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRSEL", "length": 330 }, "evidence": [ { "id": "A0A4X1VG74", "url": "https://omabrowser.org/oma/group/A0A4X1VG74/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P26885-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP2", "gene_name": "FKBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRTEL", "length": 142 }, "evidence": [ { "id": "A0A4X1VG74", "url": "https://omabrowser.org/oma/group/A0A4X1VG74/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P45878-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP2", "gene_name": "Fkbp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLSWILTILSICLSALAAATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRSEL", "length": 140 }, "evidence": [ { "id": "A0A4X1VG74", "url": "https://omabrowser.org/oma/group/A0A4X1VG74/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54SR7-1", "protein_name": "FK506-binding protein 2", "gene_name": "fkbp2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYCLLLVILALVGLSSGAKPSDKLQIGVKYRPDECTVKTKSGDKLKIHYTGTLLNGDKFDSSVDRGTPFEFKIGVGQVIKGWDQGVLGMCVGEKRKLIIPPSLGYGQQGAGDKIPGNSHLIFDVELIGIN", "length": 133 }, "evidence": [ { "id": "A0A4X1VG74", "url": "https://omabrowser.org/oma/group/A0A4X1VG74/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VGK3-1", "protein_name": "peptidylprolyl isomerase", "gene_name": "Dmel\\CG14715", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLTYILLICAFVAASAASDPKVKIGIKKRVENCTRKAKGGDLVHVHYRGALQDGTEFDSSYSRGTPFSFTLGARQVIKGWDQGILGMCEGEQRKLTIPPELGYGASGAGGGKIPPNAVLVFDTELVKIEPRSGSEEL", "length": 138 }, "evidence": [ { "id": "A0A4X1VG74", "url": "https://omabrowser.org/oma/group/A0A4X1VG74/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VG74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VG74", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1VG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VG74" }, { "id": "PS50059", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50059" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPIase FKBP-type", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 135, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U700-1", "uniprot_ac": "A0A4X1U700", "uniprot_id": "A0A4X1U700_PIG", "mass": { "chemical_mass": 17819.0, "monoisotopic_mass": 17819.0 }, "refseq": { "ac": "XP_005660499", "name": "60S ribosomal protein L12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660499" }, "gene_names": [ { "name": "RPL12", "type": "recommended", "evidence": [ { "id": "A0A4X1U700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" } ] }, { "name": "RPL12", "type": "synonym", "evidence": [ { "id": "XP_005660499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660499" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL11", "type": "recommended", "evidence": [ { "id": "A0A4X1U700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L12", "type": "synonym", "evidence": [ { "id": "XP_005660499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660499" }, { "id": "A0A4X1U700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds directly to 26S ribosomal RNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U700", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700#function" }, { "database": "UniProtKB", "id": "ARBA00045484", "url": "https://www.uniprot.org/uniprotkb/ARBA00045484#function" }, { "database": "UniProtKB", "id": "A0A287AJH8", "url": "https://www.uniprot.org/uniprotkb/A0A287AJH8#function" }, { "database": "UniProtKB", "id": "A0A287AP66", "url": "https://www.uniprot.org/uniprotkb/A0A287AP66#function" }, { "database": "UniProtKB", "id": "A0A5G2QR46", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR46#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U700", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPL12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700", "locus": {} } ], "crossref": [ { "id": "A0A4X1U700", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U700", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000033019", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000033019", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00349", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00349", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "414416", "url": "https://www.ncbi.nlm.nih.gov/gene/414416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020784", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020784", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:414416", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414416", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QPPHDVI", "url": "https://omabrowser.org/oma/group/QPPHDVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U700", "url": "https://www.orthodb.org/?gene=A0A4X1U700", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11661", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11661", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11661:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11661:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00298", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00298", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03946", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03946", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005660499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660499", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AJH8", "url": "https://www.uniprot.org/uniprotkb/A0A287AJH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AJH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AP66", "url": "https://www.uniprot.org/uniprotkb/A0A287AP66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AP66-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AP66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U700", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U700-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QR46", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QR46-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QR46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS", "length": 165, "header": "tr|A0A4X1U700-1|A0A4X1U700_PIG Isoform 1 of Large ribosomal subunit protein uL11 OS=Sus scrofa OX=9823 GN=RPL12 PE=1 SV=1 CANONICAL=A0A4X1U700-1" }, "isoforms": [ { "isoform_ac": "A0A287AJH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700/entry#A0A287AJH8-1", "sequence": { "sequence": "MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAVSDFCIGFTCLKPGELEGEAKIVWR", "length": 189, "header": "tr|A0A287AJH8-1|A0A4X1U700_PIG Computationally mapped isoform of Large ribosomal subunit protein uL11 OS=Sus scrofa OX=9823 GN=RPL12 PE=1 SV=1 CANONICAL=A0A4X1U700-1" }, "locus": { "chromosome": "1", "start_pos": 267964763, "end_pos": 267961534, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050711.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050711.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044039.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044039.1" } ] } }, { "isoform_ac": "A0A287AP66-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700/entry#A0A287AP66-1", "sequence": { "sequence": "MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAVSDFCIGFTCLKPGELEGEAKIVWR", "length": 156, "header": "tr|A0A287AP66-1|A0A4X1U700_PIG Computationally mapped isoform of Large ribosomal subunit protein uL11 OS=Sus scrofa OX=9823 GN=RPL12 PE=1 SV=3 CANONICAL=A0A4X1U700-1" }, "locus": { "chromosome": "1", "start_pos": 267964763, "end_pos": 267961534, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045592.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045592.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045808.3", "url": "https://www.ensembl.org/id/ENSSSCP00000045808.3" } ] } }, { "isoform_ac": "A0A4X1U700-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700/entry#A0A4X1U700-1", "sequence": { "sequence": "MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS", "length": 165, "header": "tr|A0A4X1U700-1|A0A4X1U700_PIG Isoform 1 of Large ribosomal subunit protein uL11 OS=Sus scrofa OX=9823 GN=RPL12 PE=1 SV=1 CANONICAL=A0A4X1U700-1" }, "locus": { "chromosome": "1", "start_pos": 267964763, "end_pos": 267961438, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081352.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081352.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072351.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072351.1" } ] } }, { "isoform_ac": "A0A5G2QR46-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700/entry#A0A5G2QR46-1", "sequence": { "sequence": "GSWFSSEKRQRVARPGPGRCGEKAVASGAPSAGTNTFFLSVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAVSDFCIGFTCLKPGELEGEAKIVWR", "length": 217, "header": "tr|A0A5G2QR46-1|A0A4X1U700_PIG Computationally mapped isoform of Large ribosomal subunit protein uL11 OS=Sus scrofa OX=9823 GN=RPL12 PE=1 SV=1 CANONICAL=A0A4X1U700-1" }, "locus": { "chromosome": "1", "start_pos": 267964283, "end_pos": 267961534, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080868.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080868.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065144.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065144.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AJH8", "url": "https://www.uniprot.org/uniprotkb/A0A287AJH8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:414416", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414416", "resource": "KEGG Pathway" }, { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BTG1-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "RPL12", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPPKFDPTEVKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGSVSFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCSIDGRHPHDIIDDINSGAIECPAS", "length": 165 }, "evidence": [ { "id": "A0A4X1U700", "url": "https://omabrowser.org/oma/group/A0A4X1U700/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P0CX53-1", "protein_name": "Large ribosomal subunit protein uL11A", "gene_name": "RPL12A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPPKFDPNEVKYLYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKEFKGIKVTVQLKIQNRQAAASVVPSASSLVITALKEPPRDRKKDKNVKHSGNIQLDEIIEIARQMRDKSFGRTLASVTKEILGTAQSVGCRVDFKNPHDIIEGINAGEIEIPEN", "length": 165 }, "evidence": [ { "id": "A0A4X1U700", "url": "https://omabrowser.org/oma/group/A0A4X1U700/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P0CX54-1", "protein_name": "Large ribosomal subunit protein uL11B", "gene_name": "RPL12B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPPKFDPNEVKYLYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKEFKGIKVTVQLKIQNRQAAASVVPSASSLVITALKEPPRDRKKDKNVKHSGNIQLDEIIEIARQMRDKSFGRTLASVTKEILGTAQSVGCRVDFKNPHDIIEGINAGEIEIPEN", "length": 165 }, "evidence": [ { "id": "A0A4X1U700", "url": "https://omabrowser.org/oma/group/A0A4X1U700/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P23358-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "Rpl12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHNGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS", "length": 165 }, "evidence": [ { "id": "A0A4X1U700", "url": "https://omabrowser.org/oma/group/A0A4X1U700/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P30050-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "RPL12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS", "length": 165 }, "evidence": [ { "id": "A0A4X1U700", "url": "https://omabrowser.org/oma/group/A0A4X1U700/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35979-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "Rpl12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPKFDPNEVKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS", "length": 165 }, "evidence": [ { "id": "A0A4X1U700", "url": "https://omabrowser.org/oma/group/A0A4X1U700/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P50883-1", "protein_name": "Large ribosomal subunit protein uL11z", "gene_name": "RPL12A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPPKLDPSQIVDVYVRVTGGEVGAASSLAPKIGPLGLAPKKIGEDIAKETAKEWKGLRVTVKLTVQNRQAKVTVVPSAAALVIKALKEPERDRKKVKNIKHNGNISFDDVTEIARIMRPRSIAKELSGTVREILGTCVSVGCTVDGKDPKDIQQEIQDGEVEIPEN", "length": 166 }, "evidence": [ { "id": "A0A4X1U700", "url": "https://omabrowser.org/oma/group/A0A4X1U700/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P61284-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "RPL12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS", "length": 165 }, "evidence": [ { "id": "A0A4X1U700", "url": "https://omabrowser.org/oma/group/A0A4X1U700/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54J50-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "rpl12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPKVDPSEKVEVFLRVCGGEAGAMSTLAPKLGPLGVSPKKVGDDIAKATQPWKGMKVSVKLTIQNRIAVPEVLPSASALVIKALKEPPRDRKKEKNIKHNGNIPLEEICKIAKTMRFKSLAVDFKGSVLEILGTAHSVGCKVNGKSPRDIQAGIQSGEIEVVEPK", "length": 166 }, "evidence": [ { "id": "A0A4X1U700", "url": "https://omabrowser.org/oma/group/A0A4X1U700/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U700", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U700", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U700", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" } ], "pmid": "" }, { "name": "large ribosomal subunit rRNA binding", "id": "GO:0070180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070180", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U700", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U700", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U700", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U700", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U700", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U700", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" }, { "id": "PF00298", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00298" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL11 C-terminal", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 143, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1U700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U700" }, { "id": "PF03946", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03946" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL11 N-terminal", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 69, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UG70-1", "uniprot_ac": "A0A4X1UG70", "uniprot_id": "A0A4X1UG70_PIG", "mass": { "chemical_mass": 26496.0, "monoisotopic_mass": 26496.0 }, "refseq": { "ac": "NP_001172089", "name": "ADP-ribosylation factor-like protein 6-interacting protein 4 isoform a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001172089" }, "gene_names": [ { "name": "ARL6IP4", "type": "recommended", "evidence": [ { "id": "A0A4X1UG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70" } ] }, { "name": "ARL6IP4", "type": "synonym", "evidence": [ { "id": "NP_001172089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001172089" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "type": "recommended", "evidence": [ { "id": "A0A4X1UG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor-like protein 6-interacting protein 4 isoform a", "type": "synonym", "evidence": [ { "id": "NP_001172089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001172089" } ] }, { "name": "ADP-ribosylation-like factor 6 interacting protein 4", "type": "synonym", "evidence": [ { "id": "NP_001172089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001172089" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UG70", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARL6IP4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70", "locus": { "chromosome": "14", "start_pos": 29886042, "end_pos": 29888470, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009782", "url": "https://www.ensembl.org/id/ENSSSCG00000009782" } ] } } ], "crossref": [ { "id": "A0A4X1UG70", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UG70", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009782", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009782", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100157752", "url": "https://www.ncbi.nlm.nih.gov/gene/100157752", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157752", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157752", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PRVMKPM", "url": "https://omabrowser.org/oma/group/PRVMKPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287AL31", "url": "https://www.orthodb.org/?gene=A0A287AL31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UG70", "url": "https://www.orthodb.org/?gene=A0A4X1UG70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF10500", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10500", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001172089", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001172089", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AL31", "url": "https://www.uniprot.org/uniprotkb/A0A287AL31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AL31-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AL31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UG70", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UG70-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKC1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHVGSRKRSRSRSRSRGRGSEKKRKKSSKDAPRSCSASRSQSRKASTTSSGAEASPSPCITERSKHKARRRPRSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKHKDKKRKKKKKRKKKLKKRSKEKAKVQQAEALPGPSLDQWHRAAEEEEDGPVLTDEQKSRIQAMKPMTKEEWDARQSVIRKVVDPETGRTRLIKGDGEVLEEIVTKERHREINKQATRGDGLAFQMRAGLLP", "length": 238, "header": "tr|A0A4X1UG70-1|A0A4X1UG70_PIG Isoform 1 of ADP-ribosylation factor-like protein 6-interacting protein 4 OS=Sus scrofa OX=9823 GN=ARL6IP4 PE=3 SV=1 CANONICAL=A0A4X1UG70-1" }, "isoforms": [ { "isoform_ac": "A0A287AL31-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70/entry#A0A287AL31-1", "sequence": { "sequence": "MAHVGSRKRSRSRSRSRGRGSEKKRKKSSKDAPRSCSASRSQSRKASTTSSGAEERSKHKARRRPRSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKHKDKKRKKKKKRKKKLKKRSKEKAKVQQAEALPGPSLDQWHRAAEEEEDGPVLTDEQKSRIQAMKPMTKEEWDARQSVIRKVVDPETGRTRLIKGDGEVLEEIVTKERHREINKQATRGDGLAFQMRAGLLP", "length": 230, "header": "tr|A0A287AL31-1|A0A4X1UG70_PIG Computationally mapped isoform of ADP-ribosylation factor-like protein 6-interacting protein 4 OS=Sus scrofa OX=9823 GN=ARL6IP4 PE=3 SV=1 CANONICAL=A0A4X1UG70-1" }, "locus": { "chromosome": "14", "start_pos": 29887980, "end_pos": 29886279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040878.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040878.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044711.2", "url": "https://www.ensembl.org/id/ENSSSCP00000044711.2" } ] } }, { "isoform_ac": "A0A4X1UG70-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70/entry#A0A4X1UG70-1", "sequence": { "sequence": "MAHVGSRKRSRSRSRSRGRGSEKKRKKSSKDAPRSCSASRSQSRKASTTSSGAEASPSPCITERSKHKARRRPRSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKHKDKKRKKKKKRKKKLKKRSKEKAKVQQAEALPGPSLDQWHRAAEEEEDGPVLTDEQKSRIQAMKPMTKEEWDARQSVIRKVVDPETGRTRLIKGDGEVLEEIVTKERHREINKQATRGDGLAFQMRAGLLP", "length": 238, "header": "tr|A0A4X1UG70-1|A0A4X1UG70_PIG Isoform 1 of ADP-ribosylation factor-like protein 6-interacting protein 4 OS=Sus scrofa OX=9823 GN=ARL6IP4 PE=3 SV=1 CANONICAL=A0A4X1UG70-1" }, "locus": { "chromosome": "14", "start_pos": 29887980, "end_pos": 29886279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010724.4", "url": "https://www.ensembl.org/id/ENSSSCT00000010724.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010444.2", "url": "https://www.ensembl.org/id/ENSSSCP00000010444.2" } ] } }, { "isoform_ac": "A0A8W4FKC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70/entry#A0A8W4FKC1-1", "sequence": { "sequence": "MAHVGSRKRSRSRSRSRGRGSEKKRKKSSKDAPRSCSASRSQKRSKHKARRRPRSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKHKDKKRKKKKKRKKKLKKRSKEKAKVQQAEALPGPSLDQWHRAAEEEEDGPVLTDEQKSRIQAMKPMTKEEWDARQSVIRKVVDPETGRTRLIKGDGEVLEEIVTKERHREINKVGVVLLPAHPQLRCS", "length": 215, "header": "tr|A0A8W4FKC1-1|A0A4X1UG70_PIG Computationally mapped isoform of ADP-ribosylation factor-like protein 6-interacting protein 4 OS=Sus scrofa OX=9823 GN=ARL6IP4 PE=3 SV=1 CANONICAL=A0A4X1UG70-1" }, "locus": { "chromosome": "14", "start_pos": 29887980, "end_pos": 29886363, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092264.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092264.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079672.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079672.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FKC1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKC1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157752", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157752", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HQ80-1", "protein_name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "gene_name": "Arl6ip4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAHVGSRKRSRSRSRSRGRRGSEKRSKKSSKDASKNCSASKSPGHKACSTSEERSKHKARRTARSSSSSSSSSSSSSASSSSSSDGRKKRGKNKDKKRKKKKKRKKKLKRKGKEKAVVLHPAEALPGPSLDQWHKSAGEDDGPVLTDEQKSRIQAMKPMTKEEWDARQSVIRKVVDPETGRTRLIKGDGEVLEEIVTKERHREINKQATRGDGLAFQMRAGLLP", "length": 224 }, "evidence": [ { "id": "A0A4X1UG70", "url": "https://omabrowser.org/oma/group/A0A4X1UG70/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9TN08-1", "protein_name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "gene_name": "ARL6IP4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAHVGSRKRSRSRSRSRGRGSEKKRKKSSKDVRRSCSASRSQSRKASSTSSGAEERSKHKARRRPRSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKHKDKKRKKKKKKRKKKLKKRGKEKARMQQTEALPGPSLDQWHRAAKEEEDGPVLTDEQKSRIQAMKPMTKEEWDARQSVIRKVVDPETGRTRLIKGDGEVLEEIVTKERHREINKQATRGDGLAFQMRAGLLP", "length": 231 }, "evidence": [ { "id": "A0A4X1UG70", "url": "https://omabrowser.org/oma/group/A0A4X1UG70/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4V8I5-1", "protein_name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "gene_name": "Arl6ip4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHVSSRKRSRSRSRSRGRRGSEKRSKRSSKDSSRNCSTSKSQGHKASSTSGVEERSKHKAQRTSRSSSSSSSSSSSSSSSSTSSSSSSDGRKKRGKHKDKKKRKKKKKRKKKMKRKGKEKAVVVHQAEALPGPSLDQWHRSAGEDNDGPVLTDEQKSRIQAMKPMTKEEWDARQSVIRKVVDPETGRTRLIKGDGEVLEEIVTKERHREINKQATRGDGLAFQMRAGLLP", "length": 231 }, "evidence": [ { "id": "A0A4X1UG70", "url": "https://omabrowser.org/oma/group/A0A4X1UG70/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q55D05-1", "protein_name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTDINRHRYRDRSDSRSRERYENRHKLYRDRSRSRSRSIDKERYHESDRHRLYRDRSKSRERDRINTKHDKNNLEIDKKRNTERDENKYRDRDKNRGRSRSRSKSRERYKKYKRNRSRSSSSSSSSSSSSSSSSSSSNERKKRKKKKKEEKRKRKKEKKEKKEEKELKKKLKKDSKKSSSTVSTTTTTTTTAAAASATNTSNLVNNNNNKKKMGPISDEDYEKLKNSYREVFDEDSGRTRVVNGNGEIVERIVSREQHKAINYIATHHPTQFK", "length": 273 }, "evidence": [ { "id": "A0A4X1UG70", "url": "https://omabrowser.org/oma/group/A0A4X1UG70/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9JM93-1", "protein_name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "gene_name": "Arl6ip4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAHVGSRKRSRSRSRSRSGRRGSEKRSKRSSKDASRNCSASRSQGHKAGSASGVEERSKHKAQRTSRSSSTSSSSSSSSSASSSSSSDGRKKRAKHKEKKRKKKKKKRKKKLKKRVKEKAVAVHQAEALPGPSLDQWHRSAGEDNDGPVLTDEQKSRIQAMKPMTKEEWDARQSVIRKVVDPETGRTRLIKGDGEVLEEIVTKERHREINKQATRGDGLAFQMRTGLLP", "length": 229 }, "evidence": [ { "id": "A0A4X1UG70", "url": "https://omabrowser.org/oma/group/A0A4X1UG70/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UG70", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UG70", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UG70", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UG70", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UG70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1V7D8-1", "uniprot_ac": "A0A4X1V7D8", "uniprot_id": "A0A4X1V7D8_PIG", "mass": { "chemical_mass": 72338.0, "monoisotopic_mass": 72338.0 }, "refseq": {}, "gene_names": [ { "name": "GLB1L2", "type": "recommended", "evidence": [ { "id": "A0A4X1V7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8" } ] } ], "protein_names": [ { "name": "Beta-galactosidase", "type": "recommended", "evidence": [ { "id": "A0A4X1V7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.23", "type": "synonym", "evidence": [ { "id": "A0A4X1V7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7D8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GLB1L2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8", "locus": { "chromosome": "9", "start_pos": 60993588, "end_pos": 60954524, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015258", "url": "https://www.ensembl.org/id/ENSSSCG00000015258" } ] } } ], "crossref": [ { "id": "A0A4X1V7D8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1V7D8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015258", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015258", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100520582", "url": "https://www.ncbi.nlm.nih.gov/gene/100520582", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520582", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520582", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GSEIVHN", "url": "https://omabrowser.org/oma/group/GSEIVHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1V7D8", "url": "https://www.orthodb.org/?gene=A0A4X1V7D8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23421", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23421", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01301", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01301", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2022857", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022857", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2024101", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2024101", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9840310", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287APF2", "url": "https://www.uniprot.org/uniprotkb/A0A287APF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287APF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287APF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B239", "url": "https://www.uniprot.org/uniprotkb/A0A287B239", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B239-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B239-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V7D8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V7D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V7Y3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V7Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLK8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPE5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKWNVRRPGRLLGLLLLVILSFLVLRRLNWSSLAPSWLRHRQLGLQAKDQNFMLEDSAFWIFGGSVHYFRVPRAYWRDRLLKMKACGLNTLTTYVPWNLHEPERGKFDFSGNLDMEAFILLAAEVGLWVILRPGPYICSEIDLGGLPSWLLQDSSMKLRTTYEGFTKAVDLYFDHLMARVVPLQYKNGGPIIAVQVENEYGSYNKDPAYMPYIKKALEDRGIVELLLTSDNEDGLSKGTVDGVLATINLQSQNELRLLHNFLQSVQGVRPKMVMEYWTGWFDSWGGPHHILDTSEVLRTVSAIIDAGASINLYMFHGGTNFGFINGAMHFQDYMSDVTSYDYDAVLTEAGDYTPKYIRLRELFGSISGASLPLPPDLLPKVRYEPVVPAFYLSLWDALPYIKEPVTSEKPVNMENLPINDGNGQSFGYTLYETTITSSGILSALVRDRGQVFLNTETIGFLDYKTKKIPIPLIQGFTILRILVENCGRVNYGENIDNQRKGLIGDIYLNDTPLKKFKIYSLDMKKSFFQRFTAEKWDPVPGVPTLPAFFLGALSVTSFPYDTFVKLEGWEKGVVFVNGYNLGRYWNIGPQETLYLPGVWLNEGINQVIVFEEMMQGPVIQFMEMPYLGRQQYVE", "length": 635, "header": "tr|A0A4X1V7D8-1|A0A4X1V7D8_PIG Isoform 1 of Beta-galactosidase OS=Sus scrofa OX=9823 GN=GLB1L2 PE=1 SV=1 CANONICAL=A0A4X1V7D8-1" }, "isoforms": [ { "isoform_ac": "A0A287APF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8/entry#A0A287APF2-1", "sequence": { "sequence": "MPKWNVRRPGRLLGLLLLVILSFLVLRRFLTLQPGSCDHEVARRLNWSSLAPSWLRHRQLGLQAKDQNFMLEDSAFWIFGGSVHYFRVPRAYWRDRLLKMKACGLNTLTTYVPWNLHEPERGKFDFSGNLDMEAFILLAAEVGLWVILRPGPYICSEIDLGGLPSWLLQDSSMKLRTTYEGFTKAVDLYFDHLMARVVPLQYKNGGPIIAVQVENEYGSYNKDPAYMPYIKKALEDRGIVELLLTSDNEDGLSKGTVDGVLATINLQSQNELRLLHNFLQSVQGVRPKMVMEYWTGWFDSWGGPHHILDTSEVLRTVSAIIDAGASINLYMFHGGTNFGFINGAMHFQDYMSDVTSYDYDAVLTEAGDYTPKYIRLRELFGSISGVKVPEDVRKPLSACSPASWQGASLPLPPDLLPKVRYEPVVPAFYLSLWDALPYIKEPVTSEKPVNMENLPINDGNGQSFGYTLYETTITSSGILSALVRDRGQVFLNTETIGFLDYKTKKIPIPLIQGFTILRILVENCGRVNYGENIDNQRKGLIGDIYLNDTPLKKFKIYSLDMKKSFFQRFTAEKWDPVPGVPTLPAFFLGALSVTSFPYDTFVKLEGWEKGVVFVNGYNLGRYWNIGPQETLYLPGVWLNEGINQVIVFEEMMQGPVIQFMEMPYLGRQQYVE", "length": 672, "header": "tr|A0A287APF2-1|A0A4X1V7D8_PIG Computationally mapped isoform of Beta-galactosidase OS=Sus scrofa OX=9823 GN=GLB1L2 PE=1 SV=2 CANONICAL=A0A4X1V7D8-1" }, "locus": { "chromosome": "9", "start_pos": 60992727, "end_pos": 60954585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065581.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065581.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045936.2", "url": "https://www.ensembl.org/id/ENSSSCP00000045936.2" } ] } }, { "isoform_ac": "A0A287B239-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8/entry#A0A287B239-1", "sequence": { "sequence": "MITFVTTCSRQIPEWPVIPEFGQWASVLSNRVPLSRFLTLQPGSCDHEVARRLNWSSLAPSWLRHRQLGLQAKDQNFMLEDSAFWIFGGSVHYFRVPRAYWRDRLLKMKACGLNTLTTYVPWNLHEPERGKFDFSGNLDMEAFILLAAEVGLWVILRPGPYICSEIDLGGLPSWLLQDSSMKLRTTYEGFTKAVDLYFDHLMARVVPLQYKNGGPIIAVQVENEYGSYNKDPAYMPYIKKALEDRGIVELLLTSDNEDGLSKGTVDGVLATINLQSQNELRLLHNFLQSVQGVRPKMVMEYWTGWFDSWGGPHHILDTSEVLRTVSAIIDAGASINLYMFHGGTNFGFINGAMHFQDYMSDVTSYDYDAVLTEAGDYTPKYIRLRELFGSISGVKVPEDVRKPLSACSPASWQGASLPLPPDLLPKVRYEPVVPAFYLSLWDALPYIKEPVTSEKPVNMENLPINDGNGQSFGYTLYETTITSSGILSALVRDRGQVFLNTETIGFLDYKTKKIPIPLIQGFTILRILVENCGRVNYGENIDNQRKGLIGDIYLNDTPLKKFKIYSLDMKKSFFQRFTAEKWDPVPGVPTLPAFFLGALSVTSFPYDTFVKLEGWEKGVVFVNGYNLGRYWNIGPQETLYLPGVWLNEGINQVGQEGQKSWPGPVIQFMEMPYLGRQQYVE", "length": 681, "header": "tr|A0A287B239-1|A0A4X1V7D8_PIG Computationally mapped isoform of Beta-galactosidase OS=Sus scrofa OX=9823 GN=GLB1L2 PE=1 SV=3 CANONICAL=A0A4X1V7D8-1" }, "locus": { "chromosome": "9", "start_pos": 60992727, "end_pos": 60963760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059277.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059277.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050314.3", "url": "https://www.ensembl.org/id/ENSSSCP00000050314.3" } ] } }, { "isoform_ac": "A0A4X1V7D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8/entry#A0A4X1V7D8-1", "sequence": { "sequence": "MPKWNVRRPGRLLGLLLLVILSFLVLRRLNWSSLAPSWLRHRQLGLQAKDQNFMLEDSAFWIFGGSVHYFRVPRAYWRDRLLKMKACGLNTLTTYVPWNLHEPERGKFDFSGNLDMEAFILLAAEVGLWVILRPGPYICSEIDLGGLPSWLLQDSSMKLRTTYEGFTKAVDLYFDHLMARVVPLQYKNGGPIIAVQVENEYGSYNKDPAYMPYIKKALEDRGIVELLLTSDNEDGLSKGTVDGVLATINLQSQNELRLLHNFLQSVQGVRPKMVMEYWTGWFDSWGGPHHILDTSEVLRTVSAIIDAGASINLYMFHGGTNFGFINGAMHFQDYMSDVTSYDYDAVLTEAGDYTPKYIRLRELFGSISGASLPLPPDLLPKVRYEPVVPAFYLSLWDALPYIKEPVTSEKPVNMENLPINDGNGQSFGYTLYETTITSSGILSALVRDRGQVFLNTETIGFLDYKTKKIPIPLIQGFTILRILVENCGRVNYGENIDNQRKGLIGDIYLNDTPLKKFKIYSLDMKKSFFQRFTAEKWDPVPGVPTLPAFFLGALSVTSFPYDTFVKLEGWEKGVVFVNGYNLGRYWNIGPQETLYLPGVWLNEGINQVIVFEEMMQGPVIQFMEMPYLGRQQYVE", "length": 635, "header": "tr|A0A4X1V7D8-1|A0A4X1V7D8_PIG Isoform 1 of Beta-galactosidase OS=Sus scrofa OX=9823 GN=GLB1L2 PE=1 SV=1 CANONICAL=A0A4X1V7D8-1" }, "locus": { "chromosome": "9", "start_pos": 60992727, "end_pos": 60954585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038931.2", "url": "https://www.ensembl.org/id/ENSSSCT00000038931.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040190.1", "url": "https://www.ensembl.org/id/ENSSSCP00000040190.1" } ] } }, { "isoform_ac": "A0A4X1V7Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8/entry#A0A4X1V7Y3-1", "sequence": { "sequence": "MPKWNVRRPGRLLGLLLLVILSFLVLRRLNWSSLAPSWLRHRQLGLQAKDQNFMLEDSAFWIFGGSVHYFRVPRAYWRDRLLKMKACGLNTLTTYVPWNLHEPERGKFDFSGNLDMEAFILLAAEVGLWVILRPGPYICSEIDLGGLPSWLLQDSSMKLRTTYEGFTKAVDLYFDHLMARVVPLQYKNGGPIIAVQVENEYGSYNKDPAYMPYIKKALEDRGIVELLLTSDNEDGLSKGTVDGVLATINLQSQNELRLLHNFLQSVQGVRPKMVMEYWTGWFDSWGGPHHILDTSEVLRTVSAIIDAGASINLYMFHGGTNFGFINGAMHFQDYMSDVTSYGASLPLPPDLLPKVRYEPVVPAFYLSLWDALPYIKEPVTSEKPVNMENLPINDGNGQSFGYTLYETTITSSGILSALVRDRGQVFLNTETIGFLDYKTKKIPIPLIQGFTILRILVENCGRVNYGENIDNQRKGLIGDIYLNDTPLKKFKIYSLDMKKSFFQRFTAEKWDPVPGVPTLPAFFLGALSVTSFPYDTFVKLEGWEKGVVFVNGYNLGRYWNIGPQETLYLPGVWLNEGINQVIVFEEMMQGPVIQFMEMPYLGRQQYVE", "length": 608, "header": "tr|A0A4X1V7Y3-1|A0A4X1V7Y3_PIG Computationally mapped isoform of Beta-galactosidase OS=Sus scrofa OX=9823 GN=GLB1L2 PE=1 SV=1 CANONICAL=A0A4X1V7D8-1" }, "locus": { "chromosome": "9", "start_pos": 60992727, "end_pos": 60954585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016627.3", "url": "https://www.ensembl.org/id/ENSSSCT00000016627.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016181.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016181.3" } ] } }, { "isoform_ac": "A0A5G2QLK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8/entry#A0A5G2QLK8-1", "sequence": { "sequence": "PRLLLSPPRYPWLLCSHRLNWSSLAPSWLRHRQLGLQAKDQNFMLEDSAFWIFGGSVHYFRVPRAYWRDRLLKMKACGLNTLTTYVPWNLHEPERGKFDFSGNLDMEAFILLAAEVGLWVILRPGPYICSEIDLGGLPSWLLQDSSMKLRTTYEGFTKAVDLYFDHLMARVVPLQYKNGGPIIAVQVENEYGSYNKDPAYMPYIKKALEDRGIVELLLTSDNEDGLSKGTVDGVLATINLQSQNELRLLHNFLQSVQGVRPKMVMEYWTGWFDSWGGPHHILDTSEVLRTVSAIIDAGASINLYMFHGGTNFGFINGAMHFQDYMSDVTSYDYDAVLTEAGDYTPKYIRLRELFGSISGASLPLPPDLLPKVRYEPVVPAFYLSLWDALPYIKEPVTSEKPVNMENLPINDGNGQSFGYTLYETTITSSGILSALVRDRGQGFTILRILVENCGRVNYGENIDNQRKGLIGDIYLNDTPLKKFKIYSLDMKKSFFQRFTAEKWDPVPGVPTLPAFFLGALSVTSFPYDTFVKLEGWEKGVVFVNGYNLGRYWNIGPQETLYLPGVWLNEGINQVGQEGQKSWPGPVIQFMEMPYLGRQQYVE", "length": 602, "header": "tr|A0A5G2QLK8-1|A0A5G2QLK8_PIG Computationally mapped isoform of Beta-galactosidase OS=Sus scrofa OX=9823 GN=GLB1L2 PE=1 SV=2 CANONICAL=A0A4X1V7D8-1" }, "locus": { "chromosome": "9", "start_pos": 60992727, "end_pos": 60964293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085961.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085961.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065726.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065726.2" } ] } }, { "isoform_ac": "A0A5G2QPE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8/entry#A0A5G2QPE5-1", "sequence": { "sequence": "PRLLLSPPRYPWLLCSHRLNWSSLAPSWLRHRQLGLQAKDQNFMLEDSAFWIFGGSVHYFRVPRAYWRDRLLKMKACGLNTLTTYVPWNLHEPERGKFDFSGNLDMEAFILLAAEVGLWVILRPGPYICSEIDLGGLPSWLLQDSSMKLRTTYEGFTKAVDLYFDHLMARVVPLQYKNGGPIIAVQVENEYGSYNKDPAYMPYIKKALEDRGIVELLLTSDNEDGLSKGTVDGVLATINLQSQNELRLLHNFLQSVQGVRPKMVMEYWTGWFDSWGGPHHILDTSEVLRTVSAIIDAGASINLYMFHGGTNFGFINGAMHFQDYMSDVTSYDYDAVLTEAGDYTPKYIRLRELFGSISGVKVPEDVRKPLSACSPASWQGASLPLPPDLLPKVRYEPVVPAFYLSLWDALPYIKEPVTSEKPVNMENLPINDGNGQSFGYTLYETTITSSGILSALVRDRGQVFLNTETIGFLDYKTKKIPIPLIQGFTILRILVENCGRVNYGENIDNQRKGLIGDIYLNDTPLKKFKIYSLDMKKSFFQRFTAEKWDPVPGVPTLPAFFLGALSVTSFPYDTFVKLEGWEKGVVFVNGYNLGRYWNIGPQETLYLPGVWLNEGINQVGVLFLRPLLVPALPGSQSFPGGAVGEQEGQKSWPAPSLRALMWL", "length": 663, "header": "tr|A0A5G2QPE5-1|A0A5G2QPE5_PIG Computationally mapped isoform of Beta-galactosidase OS=Sus scrofa OX=9823 GN=GLB1L2 PE=1 SV=2 CANONICAL=A0A4X1V7D8-1" }, "locus": { "chromosome": "9", "start_pos": 60992616, "end_pos": 60964293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089646.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089646.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066570.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066570.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287APF2", "url": "https://www.uniprot.org/uniprotkb/A0A287APF2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520582", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520582", "resource": "KEGG Pathway" }, { "id": "R-SSC-2022857", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022857", "resource": "Reactome", "description": "Keratan sulfate degradation" }, { "id": "R-SSC-2024101", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2024101", "resource": "Reactome", "description": "CS/DS degradation" }, { "id": "R-SSC-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABI0P643-1", "protein_name": "Beta-galactosidase", "gene_name": "GLB1L2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKWSVRRRPSLLLGAVLLIVCLPVLRRYLHRQPGGCDLEVTPRLDWSGLGASLWRRRHLGLRADGQNFKLENSAFWIFGGSVHYFRVPRAYWRDRLLKLRACGLNTLTTYVPWNLHEPERGTFDFSGNLDLEAFILLAAEVGLWVILRPGPYICSEVDLGGLPSWLLRDPDMRLRTTYKGFTEAVDLYFDHLMLRVVPLQYKHGGPIIAVQVENEYGSYNKDPAYMPYIKKALQDRGIAELLLTSDNQGGLKSGVLDGVLATINLQSQSELQLFTTILLGAQGSQPKMVMEYWTGWFDSWGGPHYILDSSEVLNTVSAIVKAGSSINLYMFHGGTNFGFIGGAMHFQDYKPDVTSYDYDAVLTEAGDYTAKYTKLREFFGSMAGAPLPVPPDLLPKTAYDPVTPAFYVSLWDALNFLELPVTSEHPVNMENLPINGGSGQSFGYTLYETTITASGVLTALVRDRGQVFLNTFFLGTLDYKKKTIVIPTVQGFTTLRILVENCGRVNYGDNIDQQRKGIIGNVYLNDSPLKKFKIYSLEMDRSFLQRFTADKWKPLTEEPMFPAFFLGALSVLDSPYDTFVKLEGWEKGVVFINNQNLGRYWNIGPQETLYLPGAWLDVGLNKIIVFEEKMAQRIIQFVDTPNLGQHEYVH", "length": 651 }, "evidence": [ { "id": "A0A4X1V7D8", "url": "https://omabrowser.org/oma/group/A0A4X1V7D8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LJW5-1", "protein_name": "Beta-galactosidase", "gene_name": "Glb1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKWSLRRRPGRTLGLLLLLVLSFLVLRRLNWTSVLPLWLQRQRLGLRTKGPNFMLEDSTFQILGGSIHYFRVPREYWRDRLLKLKACGLNTLTTYVPWNLHEPERGKFDFSGNLDLEAFIWLAAKIGLWVILRPGPYICSEIDLGGLPSWLLQDPDMKLRTTYPGFTKAVDLYFDHLMSRVVPLQYKHGGPIIAVQVENEYGSYNGDHAYMPYIKKALEDRGIIEMLLTSDNKDGLEKGVVDGVLATINLQSQQELVALNSILLSIQGIQPKMVMEYWTGWFDSWGGSHNILDSSEVLQTVSAIIKDGSSINLYMFHGGTNFGFINGAMHFGDYKADVTSYDYDAILTEAGDYTAKYTKLRELFGTFSGVPPPPPPELTAKMVYEPVTPSFYLSLWDALLYMDKPITSEIPINMENLPVNNGNGQAFGYVLYETTIFSSGVLSGLVRDRGQVFLNRVSIGFLDYTTTKITIPLTQGYTILRILVENRGRVNYGNNIDSQRKGLIGNLYLNNKPLKNFKIYSLDMTKQFFQRFDMDKWSVVPKEITFPAFFLGTLSVGIYPSDTFLKLEGWVKGVVLVNDHNLGRYWNVGPQETLYLPGVWLDKGLNKVIIFEETMAGSMVQSTDIPHLGRNQYVN", "length": 636 }, "evidence": [ { "id": "A0A4X1V7D8", "url": "https://omabrowser.org/oma/group/A0A4X1V7D8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UPY5-1", "protein_name": "Beta-galactosidase-1-like protein 2", "gene_name": "Glb1l2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKWSLRRRPGRTLGLLLLLVLSFLVLRRLNWSTLVPLWLQHQRLGLRTKGPDFILEDSIFQILGGSIHYFRVPREYWRDRLLKLKACGLNTLTTYVPWNLHEPERGKFDFSGNLDLEAFIQLAAKIGLWVILRPGPYICSEIDLGGLPSWLLQDPDMKLRTTYHGFTKAVELYFDHLMSRVVPLQYKHGGPIIAVQVENEYGSYNKDRAYMPYIKKALEDRGIIEMLLTSDNKDGLEKGVVDGVLATINLQSQQELMALNTVLLSIQGIQPKMVMEYWTGWFDSWGGSHNILDSSEVLQTVSAIIKDGSSINLYMFHGGTNFGFINGAMHFNDYKADVTSYDYDAILTEAGDYTAKYTKLRELFGTVSGIPPPPPPELTAKMVYEPMSPALYLSLWDAIQYMDKPVTSETPINMENLPVNNGNGQAFGYVLYETTIFSSGVLSGLVRDRGQVFLNRVSIGFLDYKTTKITIPLTQGYTILRILVENRGRVNYGNNIDSQRKGLIGNLYLNNKALKNFKIYSLDMTKQFLQRFDMDNWSVIPKELTFPAFFLGALSVGIYPSDTFLKLEGWVKGVVFVNGHNLGRYWNVGPQETLYLPGVWLDKGINKVIIFEETMSGSMVQSTDIPHLGRNQYIN", "length": 636 }, "evidence": [ { "id": "A0A4X1V7D8", "url": "https://omabrowser.org/oma/group/A0A4X1V7D8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IW92-1", "protein_name": "Beta-galactosidase-1-like protein 2", "gene_name": "GLB1L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTWSLRRRPARTLGLLLLVVLGFLVLRRLDWSTLVPLRLRHRQLGLQAKGWNFMLEDSTFWIFGGSIHYFRVPREYWRDRLLKMKACGLNTLTTYVPWNLHEPERGKFDFSGNLDLEAFVLMAAEIGLWVILRPGPYICSEMDLGGLPSWLLQDPGMRLRTTYKGFTEAVDLYFDHLMSRVVPLQYKRGGPIIAVQVENEYGSYNKDPAYMPYVKKALEDRGIVELLLTSDNKDGLSKGIVQGVLATINLQSTHELQLLTTFLFNVQGTQPKMVMEYWTGWFDSWGGPHNILDSSEVLKTVSAIVDAGSSINLYMFHGGTNFGFMNGAMHFHDYKSDVTSYDYDAVLTEAGDYTAKYMKLRDFFGSISGIPLPPPPDLLPKMPYEPLTPVLYLSLWDALKYLGEPIKSEKPINMENLPVNGGNGQSFGYILYETSITSSGILSGHVHDRGQVFVNTVSIGFLDYKTTKIAVPLIQGYTVLRILVENRGRVNYGENIDDQRKGLIGNLYLNDSPLKNFRIYSLDMKKSFFQRFGLDKWSSLPETPTLPAFFLGSLSISSTPCDTFLKLEGWEKGVVFINGQNLGRYWNIGPQKTLYLPGPWLSSGINQVIVFEETMAGPALQFTETPHLGRNQYIK", "length": 636 }, "evidence": [ { "id": "A0A4X1V7D8", "url": "https://omabrowser.org/oma/group/A0A4X1V7D8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7D8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8" } ], "pmid": "" }, { "name": "galactose catabolic process", "id": "GO:0019388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019388", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7D8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "beta-galactosidase activity", "id": "GO:0004565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004565", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7D8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7D8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-1605624", "name": "Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal membrane, lysosomal lumen", "input_participant_list": [ "R-ALL-1605715" ], "output_participant_list": [ "R-ALL-1605637" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1605624", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1605624" } ] }, { "id": "R-SSC-1606312", "name": "GLB1 hydrolyzes SapB/C:LacCer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1606312", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1606312" } ] }, { "id": "R-SSC-1630306", "name": "GLB1 hydrolyses a glycosaminoglycan", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2104997" ], "output_participant_list": [ "R-ALL-2104995" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1630306", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1630306" } ] }, { "id": "R-SSC-2090079", "name": "GLB1 hydrolyses linker chain(2)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2090075" ], "output_participant_list": [ "R-ALL-2090063" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2090079", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2090079" } ] }, { "id": "R-SSC-9840795", "name": "Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9840795", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840795" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1605637", "participant_name": "Gal [lysosomal lumen]", "crossref": [ { "id": "ZINC000000901155", "database": "ZINC", "url": "" }, { "id": "C00984", "database": "COMPOUND", "url": "" }, { "id": "HMDB0000143", "database": "HMDB Metabolite", "url": "" }, { "id": "4646", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "28061", "database": "ChEBI", "url": "" }, { "id": "G09546QO", "database": "GlyTouCan", "url": "" } ] }, { "participant_id": "R-ALL-1605715", "participant_name": "H2O [lysosomal lumen]", "crossref": [ { "id": "15377", "database": "ChEBI", "url": "" }, { "id": "8145132", "database": "PubChem Substance", "url": "" }, { "id": "C00001", "database": "COMPOUND", "url": "" }, { "id": "HMDB0002111", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-2090063", "participant_name": "D-xylose [lysosomal lumen]", "crossref": [ { "id": "C00181", "database": "COMPOUND", "url": "" }, { "id": "ZINC000018168715", "database": "ZINC", "url": "" }, { "id": "4724", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "15936", "database": "ChEBI", "url": "" }, { "id": "G01550VL", "database": "GlyTouCan", "url": "" } ] }, { "participant_id": "R-ALL-2090075", "participant_name": "linker chain(2) [lysosomal lumen]", "crossref": [ { "id": "154964", "database": "ChEBI", "url": "" }, { "id": "G87877ES", "database": "GlyTouCan", "url": "" } ] }, { "participant_id": "R-ALL-2104995", "participant_name": "GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]", "crossref": [ { "id": "ZINC000096085297", "database": "ZINC", "url": "" }, { "id": "63851", "database": "ChEBI", "url": "" }, { "id": "G80016QC", "database": "GlyTouCan", "url": "" }, { "id": "G06780", "database": "KEGG Glycan", "url": "" }, { "id": "ZINC000096085298", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2104997", "participant_name": "Gal-GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]", "crossref": [ { "id": "63850", "database": "ChEBI", "url": "" }, { "id": "G13032", "database": "KEGG Glycan", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1V7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8" }, { "id": "PF21317", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21317" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-galactosidase 1-like first all-beta", "eco_id": "ECO_0000259", "start_pos": 424, "end_pos": 523, "start_aa": "Gly", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1V7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8" }, { "id": "PF21467", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21467" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-galactosidase galactose-binding", "eco_id": "ECO_0000259", "start_pos": 547, "end_pos": 606, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1V7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7D8" }, { "id": "PF01301", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01301" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycoside hydrolase 35 catalytic", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 365, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 }, { "start_pos": 510, "end_pos": 512 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1V1H9-1", "uniprot_ac": "A0A4X1V1H9", "uniprot_id": "A0A4X1V1H9_PIG", "mass": { "chemical_mass": 79540.0, "monoisotopic_mass": 79540.0 }, "refseq": { "ac": "XP_003133651", "name": "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133651" }, "gene_names": [ { "name": "NDUFS1", "type": "recommended", "evidence": [ { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ] }, { "name": "NDUFS1", "type": "synonym", "evidence": [ { "id": "XP_003133651", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133651" } ] } ], "protein_names": [ { "name": "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9/entry#names_and_taxonomy" } ] }, { "name": "7.1.1.2", "type": "synonym", "evidence": [ { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9/entry#names_and_taxonomy" } ] }, { "name": "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003133651", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133651" } ] } ], "function": [ { "annotation": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for catalysing the entry and efficient transfer of electrons within complex I. Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BLV7", "url": "https://www.uniprot.org/uniprotkb/A0A287BLV7#function" }, { "database": "UniProtKB", "id": "ARBA00045300", "url": "https://www.uniprot.org/uniprotkb/ARBA00045300#function" }, { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9#function" }, { "database": "UniProtKB", "id": "A0A5G2RBR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR3#function" }, { "database": "UniProtKB", "id": "A0A287ARY3", "url": "https://www.uniprot.org/uniprotkb/A0A287ARY3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NDUFS1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9", "locus": { "chromosome": "15", "start_pos": 109409771, "end_pos": 109451676, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016127", "url": "https://www.ensembl.org/id/ENSSSCG00000016127" } ] } } ], "crossref": [ { "id": "A0A4X1V1H9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1V1H9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016127", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016127", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00207", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00207", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02773", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02773", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100516402", "url": "https://www.ncbi.nlm.nih.gov/gene/100516402", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "5GPN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5GPN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "5GUP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5GUP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2C", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2C&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2D&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2E", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2E&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2F", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2F&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2H", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2H&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2K", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2K&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V30", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V30&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V31", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V31&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V32", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V32&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V33", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V33&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V3M", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V3M&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VB7", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VB7&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VBN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VBN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VBZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VBZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VWJ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VWJ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VXP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VXP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VY8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VY8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYA", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYA&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYF", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYF&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VYN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VYN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZ1", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZ1&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZV", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZV&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7VZW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7VZW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W00", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W00&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W0H", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W0H&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W0R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W0R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W0Y", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W0Y&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1O", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1O&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1P", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1P&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1T", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1T&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1U", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1U&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1V", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1V&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W1Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W1Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W20", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W20&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2K", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2K&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2L", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2L&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2U", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2U&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W2Y", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W2Y&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W31", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W31&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W32", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W32&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W35", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W35&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4C", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4C&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4D&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4E", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4E&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4F", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4F&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4G", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4G&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4J", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4J&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4K", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4K&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4L", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4L&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4M", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4M&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4N", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4N&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7W4Q", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7W4Q&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UD1", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UD1&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEO", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEO&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UER", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UER&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UES", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UES&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UET", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UET&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEU", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEU&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEV", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEV&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEX", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEX&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEY", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEY&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UEZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UEZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGI", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGI&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGJ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGJ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZO8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZO8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZP8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZP8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSK", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSK&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSM", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSM&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSO", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSO&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZXZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZXZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9BUH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9BUH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9BWD", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9BWD&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9BXV", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9BXV&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CD6", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CD6&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CDN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CDN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CE2", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CE2&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9J6H", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9J6H&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9J6W", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9J6W&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR000283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516402", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516402", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QAMAYGV", "url": "https://omabrowser.org/oma/group/QAMAYGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1V1H9", "url": "https://www.orthodb.org/?gene=A0A4X1V1H9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43105:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43105:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00005gpn", "url": "https://www.rcsb.org/structure/pdb_00005gpn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00005gup", "url": "https://www.rcsb.org/structure/pdb_00005gup", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2c", "url": "https://www.rcsb.org/structure/pdb_00007v2c", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2d", "url": "https://www.rcsb.org/structure/pdb_00007v2d", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2e", "url": "https://www.rcsb.org/structure/pdb_00007v2e", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2f", "url": "https://www.rcsb.org/structure/pdb_00007v2f", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2h", "url": "https://www.rcsb.org/structure/pdb_00007v2h", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2k", "url": "https://www.rcsb.org/structure/pdb_00007v2k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v2r", "url": "https://www.rcsb.org/structure/pdb_00007v2r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v30", "url": "https://www.rcsb.org/structure/pdb_00007v30", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v31", "url": "https://www.rcsb.org/structure/pdb_00007v31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v32", "url": "https://www.rcsb.org/structure/pdb_00007v32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v33", "url": "https://www.rcsb.org/structure/pdb_00007v33", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007v3m", "url": "https://www.rcsb.org/structure/pdb_00007v3m", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vb7", "url": "https://www.rcsb.org/structure/pdb_00007vb7", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vbn", "url": "https://www.rcsb.org/structure/pdb_00007vbn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vbz", "url": "https://www.rcsb.org/structure/pdb_00007vbz", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vwj", "url": "https://www.rcsb.org/structure/pdb_00007vwj", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vxp", "url": "https://www.rcsb.org/structure/pdb_00007vxp", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vy8", "url": "https://www.rcsb.org/structure/pdb_00007vy8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vya", "url": "https://www.rcsb.org/structure/pdb_00007vya", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vyf", "url": "https://www.rcsb.org/structure/pdb_00007vyf", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vyh", "url": "https://www.rcsb.org/structure/pdb_00007vyh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vyn", "url": "https://www.rcsb.org/structure/pdb_00007vyn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vz1", "url": "https://www.rcsb.org/structure/pdb_00007vz1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vzv", "url": "https://www.rcsb.org/structure/pdb_00007vzv", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007vzw", "url": "https://www.rcsb.org/structure/pdb_00007vzw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w00", "url": "https://www.rcsb.org/structure/pdb_00007w00", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w0h", "url": "https://www.rcsb.org/structure/pdb_00007w0h", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w0r", "url": "https://www.rcsb.org/structure/pdb_00007w0r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w0y", "url": "https://www.rcsb.org/structure/pdb_00007w0y", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1o", "url": "https://www.rcsb.org/structure/pdb_00007w1o", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1p", "url": "https://www.rcsb.org/structure/pdb_00007w1p", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1t", "url": "https://www.rcsb.org/structure/pdb_00007w1t", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1u", "url": "https://www.rcsb.org/structure/pdb_00007w1u", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1v", "url": "https://www.rcsb.org/structure/pdb_00007w1v", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w1z", "url": "https://www.rcsb.org/structure/pdb_00007w1z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w20", "url": "https://www.rcsb.org/structure/pdb_00007w20", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2k", "url": "https://www.rcsb.org/structure/pdb_00007w2k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2l", "url": "https://www.rcsb.org/structure/pdb_00007w2l", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2r", "url": "https://www.rcsb.org/structure/pdb_00007w2r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2u", "url": "https://www.rcsb.org/structure/pdb_00007w2u", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w2y", "url": "https://www.rcsb.org/structure/pdb_00007w2y", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w31", "url": "https://www.rcsb.org/structure/pdb_00007w31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w32", "url": "https://www.rcsb.org/structure/pdb_00007w32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w35", "url": "https://www.rcsb.org/structure/pdb_00007w35", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4c", "url": "https://www.rcsb.org/structure/pdb_00007w4c", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4d", "url": "https://www.rcsb.org/structure/pdb_00007w4d", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4e", "url": "https://www.rcsb.org/structure/pdb_00007w4e", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4f", "url": "https://www.rcsb.org/structure/pdb_00007w4f", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4g", "url": "https://www.rcsb.org/structure/pdb_00007w4g", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4j", "url": "https://www.rcsb.org/structure/pdb_00007w4j", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4k", "url": "https://www.rcsb.org/structure/pdb_00007w4k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4l", "url": "https://www.rcsb.org/structure/pdb_00007w4l", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4m", "url": "https://www.rcsb.org/structure/pdb_00007w4m", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4n", "url": "https://www.rcsb.org/structure/pdb_00007w4n", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007w4q", "url": "https://www.rcsb.org/structure/pdb_00007w4q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ud1", "url": "https://www.rcsb.org/structure/pdb_00008ud1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ueo", "url": "https://www.rcsb.org/structure/pdb_00008ueo", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uep", "url": "https://www.rcsb.org/structure/pdb_00008uep", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ueq", "url": "https://www.rcsb.org/structure/pdb_00008ueq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uer", "url": "https://www.rcsb.org/structure/pdb_00008uer", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ues", "url": "https://www.rcsb.org/structure/pdb_00008ues", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uet", "url": "https://www.rcsb.org/structure/pdb_00008uet", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ueu", "url": "https://www.rcsb.org/structure/pdb_00008ueu", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uev", "url": "https://www.rcsb.org/structure/pdb_00008uev", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uew", "url": "https://www.rcsb.org/structure/pdb_00008uew", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uex", "url": "https://www.rcsb.org/structure/pdb_00008uex", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uey", "url": "https://www.rcsb.org/structure/pdb_00008uey", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008uez", "url": "https://www.rcsb.org/structure/pdb_00008uez", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugh", "url": "https://www.rcsb.org/structure/pdb_00008ugh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugi", "url": "https://www.rcsb.org/structure/pdb_00008ugi", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugj", "url": "https://www.rcsb.org/structure/pdb_00008ugj", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugn", "url": "https://www.rcsb.org/structure/pdb_00008ugn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugr", "url": "https://www.rcsb.org/structure/pdb_00008ugr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zo8", "url": "https://www.rcsb.org/structure/pdb_00008zo8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zp8", "url": "https://www.rcsb.org/structure/pdb_00008zp8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsk", "url": "https://www.rcsb.org/structure/pdb_00008zsk", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsl", "url": "https://www.rcsb.org/structure/pdb_00008zsl", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsm", "url": "https://www.rcsb.org/structure/pdb_00008zsm", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsn", "url": "https://www.rcsb.org/structure/pdb_00008zsn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zso", "url": "https://www.rcsb.org/structure/pdb_00008zso", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsq", "url": "https://www.rcsb.org/structure/pdb_00008zsq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsr", "url": "https://www.rcsb.org/structure/pdb_00008zsr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zxz", "url": "https://www.rcsb.org/structure/pdb_00008zxz", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009buh", "url": "https://www.rcsb.org/structure/pdb_00009buh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009bwd", "url": "https://www.rcsb.org/structure/pdb_00009bwd", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009bxv", "url": "https://www.rcsb.org/structure/pdb_00009bxv", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009cd6", "url": "https://www.rcsb.org/structure/pdb_00009cd6", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009cdn", "url": "https://www.rcsb.org/structure/pdb_00009cdn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009ce2", "url": "https://www.rcsb.org/structure/pdb_00009ce2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009j6h", "url": "https://www.rcsb.org/structure/pdb_00009j6h", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009j6w", "url": "https://www.rcsb.org/structure/pdb_00009j6w", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5GPN", "url": "https://www.rcsb.org/structure/5GPN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5GUP", "url": "https://www.rcsb.org/structure/5GUP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2C", "url": "https://www.rcsb.org/structure/7V2C", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2D", "url": "https://www.rcsb.org/structure/7V2D", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2E", "url": "https://www.rcsb.org/structure/7V2E", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2F", "url": "https://www.rcsb.org/structure/7V2F", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2H", "url": "https://www.rcsb.org/structure/7V2H", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2K", "url": "https://www.rcsb.org/structure/7V2K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V2R", "url": "https://www.rcsb.org/structure/7V2R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V30", "url": "https://www.rcsb.org/structure/7V30", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V31", "url": "https://www.rcsb.org/structure/7V31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V32", "url": "https://www.rcsb.org/structure/7V32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V33", "url": "https://www.rcsb.org/structure/7V33", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7V3M", "url": "https://www.rcsb.org/structure/7V3M", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VB7", "url": "https://www.rcsb.org/structure/7VB7", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VBN", "url": "https://www.rcsb.org/structure/7VBN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VBZ", "url": "https://www.rcsb.org/structure/7VBZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VWJ", "url": "https://www.rcsb.org/structure/7VWJ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VXP", "url": "https://www.rcsb.org/structure/7VXP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VY8", "url": "https://www.rcsb.org/structure/7VY8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYA", "url": "https://www.rcsb.org/structure/7VYA", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYF", "url": "https://www.rcsb.org/structure/7VYF", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYH", "url": "https://www.rcsb.org/structure/7VYH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VYN", "url": "https://www.rcsb.org/structure/7VYN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZ1", "url": "https://www.rcsb.org/structure/7VZ1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZV", "url": "https://www.rcsb.org/structure/7VZV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7VZW", "url": "https://www.rcsb.org/structure/7VZW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W00", "url": "https://www.rcsb.org/structure/7W00", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W0H", "url": "https://www.rcsb.org/structure/7W0H", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W0R", "url": "https://www.rcsb.org/structure/7W0R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W0Y", "url": "https://www.rcsb.org/structure/7W0Y", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1O", "url": "https://www.rcsb.org/structure/7W1O", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1P", "url": "https://www.rcsb.org/structure/7W1P", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1T", "url": "https://www.rcsb.org/structure/7W1T", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1U", "url": "https://www.rcsb.org/structure/7W1U", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1V", "url": "https://www.rcsb.org/structure/7W1V", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W1Z", "url": "https://www.rcsb.org/structure/7W1Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W20", "url": "https://www.rcsb.org/structure/7W20", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2K", "url": "https://www.rcsb.org/structure/7W2K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2L", "url": "https://www.rcsb.org/structure/7W2L", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2R", "url": "https://www.rcsb.org/structure/7W2R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2U", "url": "https://www.rcsb.org/structure/7W2U", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W2Y", "url": "https://www.rcsb.org/structure/7W2Y", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W31", "url": "https://www.rcsb.org/structure/7W31", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W32", "url": "https://www.rcsb.org/structure/7W32", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W35", "url": "https://www.rcsb.org/structure/7W35", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4C", "url": "https://www.rcsb.org/structure/7W4C", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4D", "url": "https://www.rcsb.org/structure/7W4D", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4E", "url": "https://www.rcsb.org/structure/7W4E", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4F", "url": "https://www.rcsb.org/structure/7W4F", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4G", "url": "https://www.rcsb.org/structure/7W4G", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4J", "url": "https://www.rcsb.org/structure/7W4J", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4K", "url": "https://www.rcsb.org/structure/7W4K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4L", "url": "https://www.rcsb.org/structure/7W4L", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4M", "url": "https://www.rcsb.org/structure/7W4M", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4N", "url": "https://www.rcsb.org/structure/7W4N", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7W4Q", "url": "https://www.rcsb.org/structure/7W4Q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UD1", "url": "https://www.rcsb.org/structure/8UD1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEO", "url": "https://www.rcsb.org/structure/8UEO", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEP", "url": "https://www.rcsb.org/structure/8UEP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEQ", "url": "https://www.rcsb.org/structure/8UEQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UER", "url": "https://www.rcsb.org/structure/8UER", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UES", "url": "https://www.rcsb.org/structure/8UES", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UET", "url": "https://www.rcsb.org/structure/8UET", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEU", "url": "https://www.rcsb.org/structure/8UEU", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEV", "url": "https://www.rcsb.org/structure/8UEV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEW", "url": "https://www.rcsb.org/structure/8UEW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEX", "url": "https://www.rcsb.org/structure/8UEX", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEY", "url": "https://www.rcsb.org/structure/8UEY", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UEZ", "url": "https://www.rcsb.org/structure/8UEZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGH", "url": "https://www.rcsb.org/structure/8UGH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGI", "url": "https://www.rcsb.org/structure/8UGI", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGJ", "url": "https://www.rcsb.org/structure/8UGJ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGN", "url": "https://www.rcsb.org/structure/8UGN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGR", "url": "https://www.rcsb.org/structure/8UGR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZO8", "url": "https://www.rcsb.org/structure/8ZO8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZP8", "url": "https://www.rcsb.org/structure/8ZP8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSK", "url": "https://www.rcsb.org/structure/8ZSK", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSL", "url": "https://www.rcsb.org/structure/8ZSL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSM", "url": "https://www.rcsb.org/structure/8ZSM", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSN", "url": "https://www.rcsb.org/structure/8ZSN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSO", "url": "https://www.rcsb.org/structure/8ZSO", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSQ", "url": "https://www.rcsb.org/structure/8ZSQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSR", "url": "https://www.rcsb.org/structure/8ZSR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZXZ", "url": "https://www.rcsb.org/structure/8ZXZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9BUH", "url": "https://www.rcsb.org/structure/9BUH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9BWD", "url": "https://www.rcsb.org/structure/9BWD", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9BXV", "url": "https://www.rcsb.org/structure/9BXV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CD6", "url": "https://www.rcsb.org/structure/9CD6", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CDN", "url": "https://www.rcsb.org/structure/9CDN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CE2", "url": "https://www.rcsb.org/structure/9CE2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9J6H", "url": "https://www.rcsb.org/structure/9J6H", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9J6W", "url": "https://www.rcsb.org/structure/9J6W", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00384", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00384", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13510", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13510", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22117", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22117", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003133651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133651", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29091", "url": "https://www.rhea-db.org/rhea/29091", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287ARY3", "url": "https://www.uniprot.org/uniprotkb/A0A287ARY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ARY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ARY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLV7", "url": "https://www.uniprot.org/uniprotkb/A0A287BLV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BLV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V1H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBR3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRIPVTRALIGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTQPMIRNEKGLLTYTTWEDALSRVAGMLQSFQGNDVAAIAGGLVDAEALVALKDLLNRVDSDSLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVILLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGNHPFSQILKEAKKPMVVLGSSALQRSDGTAILAAVSNIAQNIRLSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPMADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRSRLEEVSPNLVRYDDVEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGIQAVEEPSIC", "length": 727, "header": "tr|A0A4X1V1H9-1|A0A4X1V1H9_PIG Isoform 1 of NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Sus scrofa OX=9823 GN=NDUFS1 PE=1 SV=1 CANONICAL=A0A4X1V1H9-1" }, "isoforms": [ { "isoform_ac": "A0A287ARY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9/entry#A0A287ARY3-1", "sequence": { "sequence": "RSGGPGGALTRISMLRIPVTRALIGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTQPMIRNEKGLLTYTTWEDALSRVAGMLQSFQGNDVAAIAGGLVDAEALVALKDLLNRVDSDSLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVILLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGNHPFSQILKEAKKPMVVLGSSALQRSDGTAILAAVSNIAQNIRLSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPMADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRSRLEEVSPNLVRYDDVEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGIQAVEEPSIC", "length": 740, "header": "tr|A0A287ARY3-1|A0A4X1V1H9_PIG Computationally mapped isoform of NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Sus scrofa OX=9823 GN=NDUFS1 PE=1 SV=1 CANONICAL=A0A4X1V1H9-1" }, "locus": { "chromosome": "15", "start_pos": 109451393, "end_pos": 109414023, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050928.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050928.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046672.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046672.2" } ] } }, { "isoform_ac": "A0A287BLV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9/entry#A0A287BLV7-1", "sequence": { "sequence": "MLRIPVTRALIGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTQPMIRNEKGLLTYTTWEDALSRVAGMLQSFQGNDVAAIAGGLVDAEALVALKDLLNRVDSDSLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVILLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGNHPFSQILKEAKKPMVVLGSSALQRSDGTAILAAVSNIAQNIRLSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPMADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRSRLEEVSPNLVRYDDVEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGIQAVEEPSIC", "length": 691, "header": "tr|A0A287BLV7-1|A0A4X1V1H9_PIG Computationally mapped isoform of NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Sus scrofa OX=9823 GN=NDUFS1 PE=1 SV=2 CANONICAL=A0A4X1V1H9-1" }, "locus": { "chromosome": "15", "start_pos": 109448501, "end_pos": 109414023, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042488.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042488.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057049.2", "url": "https://www.ensembl.org/id/ENSSSCP00000057049.2" } ] } }, { "isoform_ac": "A0A4X1V1H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9/entry#A0A4X1V1H9-1", "sequence": { "sequence": "MLRIPVTRALIGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTQPMIRNEKGLLTYTTWEDALSRVAGMLQSFQGNDVAAIAGGLVDAEALVALKDLLNRVDSDSLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVILLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGNHPFSQILKEAKKPMVVLGSSALQRSDGTAILAAVSNIAQNIRLSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPMADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRSRLEEVSPNLVRYDDVEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGIQAVEEPSIC", "length": 727, "header": "tr|A0A4X1V1H9-1|A0A4X1V1H9_PIG Isoform 1 of NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Sus scrofa OX=9823 GN=NDUFS1 PE=1 SV=1 CANONICAL=A0A4X1V1H9-1" }, "locus": { "chromosome": "15", "start_pos": 109448501, "end_pos": 109414023, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017559.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017559.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017086.4", "url": "https://www.ensembl.org/id/ENSSSCP00000017086.4" } ] } }, { "isoform_ac": "A0A5G2RBR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9/entry#A0A5G2RBR3-1", "sequence": { "sequence": "MFVIRRFFSYDNIFLLCFILSSMLRIPVTRALIGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTQPMIRNEKGLLTYTTWEDALSRVAGMLQSFQGNDVAAIAGGLVDAEALVALKDLLNRVDSDSLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVILLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGNHPFSQILKEAKKPMVVLGSSALQRSDGTAILAAVSNIAQNIRLSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPMADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRSRLEEVSPNLVRYDDVEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGIQAVEEPSIC", "length": 749, "header": "tr|A0A5G2RBR3-1|A0A4X1V1H9_PIG Computationally mapped isoform of NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Sus scrofa OX=9823 GN=NDUFS1 PE=1 SV=1 CANONICAL=A0A4X1V1H9-1" }, "locus": { "chromosome": "15", "start_pos": 109448567, "end_pos": 109414023, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073549.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073549.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071617.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071617.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 374, "start_aa": "Thr", "end_pos": 374, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr374", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 611, "start_aa": "Thr", "end_pos": 611, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr611", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The architecture of the mammalian respirasome.", "journal": "Nature", "date": "2016", "authors": "Gu Jinke, Wu Meng, Guo Runyu, Yan Kaige, Lei Jianlin, Gao Ning, Yang Maojun", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "reference": [ { "type": "PubMed", "id": "27654917", "url": "https://glygen.org/publication/PubMed/27654917" } ] }, { "title": "Structure of Mammalian Respiratory Supercomplex I1III2IV1.", "journal": "Cell", "date": "2016", "authors": "Wu Meng, Gu Jinke, Guo Runyu, Huang Yushen, Yang Maojun", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "reference": [ { "type": "PubMed", "id": "27912063", "url": "https://glygen.org/publication/PubMed/27912063" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "The coupling mechanism of mammalian mitochondrial complex I.", "journal": "Nat. Struct. Mol. Biol.", "date": "2022", "authors": "Gu Jinke, Liu Tianya, Guo Runyu, Zhang Laixing, Yang Maojun", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "reference": [ { "type": "PubMed", "id": "35145322", "url": "https://glygen.org/publication/PubMed/35145322" } ] }, { "title": "High-resolution in situ structures of mammalian respiratory supercomplexes.", "journal": "Nature", "date": "2024", "authors": "Zheng Wan, Chai Pengxin, Zhu Jiapeng, Zhang Kai", "evidence": [ { "database": "UniProtKB", "id": "A0A287ARY3", "url": "https://www.uniprot.org/uniprotkb/A0A287ARY3" } ], "reference": [ { "type": "PubMed", "id": "38811722", "url": "https://glygen.org/publication/PubMed/38811722" } ] } ], "pathway": [ { "id": "ssc:100516402", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516402", "resource": "KEGG Pathway" }, { "id": "R-SSC-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-SSC-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799198", "resource": "Reactome", "description": "Complex I biogenesis" }, { "id": "R-SSC-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HDL7-1", "protein_name": "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "gene_name": "Ndufs1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLRIPVKRAIIALSKSAKGYVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGIQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTEPMVRNEKGLLTYTSWEDALSRVAEMLQSFQGKDVAAIVGGLVDAEALVALKDLLNKVDSDNLCTEEIFPTEGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYRYNHLGDSPKILQYIASGNHLFSQVLKEAKKPMVVLGSSALQRNDGAAILAAVSNIAQMIRVTSGVSEDWKVMNILHRIASQVAALDLGYKPGIDAIRKNPPKVLFLLGADGGCVTRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGLTLPYDTLDQVRNRLEEVSPNLVRYDDVEGANYFQQATELAKLVNQKLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQAVEEPSIC", "length": 727 }, "evidence": [ { "id": "A0A4X1V1H9", "url": "https://omabrowser.org/oma/group/A0A4X1V1H9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P15690-1", "protein_name": "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "gene_name": "NDUFS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLRIPVRKALVGLSKSSKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKTKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTEPMVRNEKGLLTHTTWEDALSRVAGMLQSFQGNDVAAIAGGLVDAEALIALKDLLNRVDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGSHPFSQVLQEAKKPMVILGSSALQRNDGAAILAAVSNIAQKIRTSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIQKNPPKMLFLLGADGGCITRQDLPKDCFIVYQGHHGDVGAPIADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRNRLEEVSPNLVRYDDVEGANYFQQASELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAHAVEEPSIC", "length": 727 }, "evidence": [ { "id": "A0A4X1V1H9", "url": "https://omabrowser.org/oma/group/A0A4X1V1H9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P28331-1", "protein_name": "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "gene_name": "NDUFS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRIPVRKALVGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGNDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSFQGKDVAAIAGGLVDAEALVALKDLLNRVDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYTYDHLGDSPKILQDIASGSHPFSQVLKEAKKPMVVLGSSALQRNDGAAILAAVSSIAQKIRMTSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRNRLEEVSPNLVRYDDIEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQAVEEPSIC", "length": 727 }, "evidence": [ { "id": "A0A4X1V1H9", "url": "https://omabrowser.org/oma/group/A0A4X1V1H9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q66HF1-1", "protein_name": "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "gene_name": "Ndufs1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRIPVKRALIGLSKSPKGYVRSTGTAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSFEGKAVAAIAGGLVDAEALVALKDLLNKVDSDTLCTEEIFPNEGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGNHEFSKVLNAAKKPMVVLGSSALQRDDGAAILAAVSSIAQKIRVASGAAAEWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKLLFLLGADGGCITRQDLPKDCFIVYQGHHGDVGAPIADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLGEVSPNLVRYDDVEEANYFQQASELAKLVDQEFLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQAVEEPSIC", "length": 727 }, "evidence": [ { "id": "A0A4X1V1H9", "url": "https://omabrowser.org/oma/group/A0A4X1V1H9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91VD9-1", "protein_name": "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "gene_name": "Ndufs1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRIPIKRALIGLSNSPKGYVRTTGTAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNVIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTEPMVRNEKGLLTYTSWEDALSRVAGMLQNFEGNAVAAIAGGLVDAEALVALKDLLNKVDSDNLCTEEIFPTEGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGRHSFCEVLKDAKKPMVVLGSSALQRDDGAAILVAVSNMVQKIRVTTGVAAEWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKMLFLLGADGGCITRQDLPKDCFIVYQGHHGDVGAPMADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDIEETNYFQQASELAKLVNQEVLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQAVEEPSIC", "length": 727 }, "evidence": [ { "id": "A0A4X1V1H9", "url": "https://omabrowser.org/oma/group/A0A4X1V1H9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94511-1", "protein_name": "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "gene_name": "ND-75", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIRAPLVKALGALGSPTHQMASRAVRTSAMVAQTPAKAPEKIEVFVDDIPVQVVPGTTVLQAAAQIGVEIPRFCYHERLAVAGNCRMCLVEVEKSPKPVAACAMPVMKGWRIKTNSDLTRKAREGVMEFLLMNHPLDCPICDQGGECDLQDQAMAFGSDRSRFTDINYTGKRAVEDKDIGPLVKTIMTRCIHCTRCVRFASEIAGVDDLGTTGRGNDMQIGTYVEKLFLTELSGNVIDLCPVGALTNKPYSFVARPWEIRKVSSIDVLDAVGSNIVVSTRTNEVLRILPRENEDVNEEWLADKSRFACDGLKRQRLVAPMVRMPNGELQAVEWEGALIAVAKAIKAAGGQIAGISGQLADLEAQVALKDLLNRLGSEVVATEQGFIAGGTDNRANYLLNSTIAGLEEADAVLLVGTNPRYEAPLVNTRLRKAYVHNELQIASIGPKIDLSYDHENLGADAALVKDVCSGAHAFSKVLEGAKKPAIIIGADLLERADGAAIHATVAEYCKKLKKPNWNPFNVLQTNAAQVGALDVGYKAGAQTAVKAQPKVLFLLNADAGKVTREQLPKDCFVVYIGSHGDNGASIADAVLPGAAYTEKQGIYVNTEGRPQQTLPGVSPPGMAREDWKILRALSEVVGKPLPYDNLDELRNRLEDVAPHLTRLGQLEPAGDAGAAGTISKSIGGGAIDIKLKELRDYFMTDAISRASPTMAKCISAVNKQQRENEAKQSVAI", "length": 731 }, "evidence": [ { "id": "A0A4X1V1H9", "url": "https://omabrowser.org/oma/group/A0A4X1V1H9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "ATP synthesis coupled electron transport", "id": "GO:0042773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042773", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "pmid": "" }, { "name": "mitochondrial electron transport, NADH to ubiquinone", "id": "GO:0006120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006120", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "pmid": "" }, { "name": "NADH dehydrogenase (ubiquinone) activity", "id": "GO:0008137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008137", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on NAD(P)H", "id": "GO:0016651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016651", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V1H9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29091", "name": "", "equation": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29091", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29091" } ] }, { "id": "R-SSC-163217", "name": "Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [ "R-ALL-73663" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-163217", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163217" } ] }, { "id": "R-SSC-6788523", "name": "NUBPL transfers 4Fe-4S to Complex I subunits", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6788523", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6788523" } ] }, { "id": "R-SSC-6799179", "name": "Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6799179", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799179" } ] }, { "id": "R-SSC-6799196", "name": "The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6799196", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6799196" } ] }, { "id": "R-SSC-9838035", "name": "CLPXP binds mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9838035", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9838035" } ] }, { "id": "R-SSC-9838081", "name": "LONP1 degrades mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9838081", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9838081" } ] }, { "id": "R-SSC-9838093", "name": "LONP1 binds mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9838093", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9838093" } ] }, { "id": "R-SSC-9838289", "name": "CLPXP degrades mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9838289", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9838289" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-73663", "participant_name": "CoQ [mitochondrial inner membrane]", "crossref": [ { "id": "46245", "database": "ChEBI", "url": "" }, { "id": "C11378", "database": "COMPOUND", "url": "" }, { "id": "ZINC000085427689", "database": "ZINC", "url": "" }, { "id": "HMDB0001072", "database": "HMDB Metabolite", "url": "" }, { "id": "C00399", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "7vb7", "pdb_chain": "m", "start_pos": 29, "end_pos": 718, "overlap": "0.95", "method": "Electron_Microscopy", "type": "experimental", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/7vb7.pdb", "url_external": "https://www.rcsb.org/structure/7vb7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" }, { "id": "PS51085", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51085" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "2Fe-2S ferredoxin-type", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 108, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" }, { "id": "PS51839", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51839" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "4Fe-4S His(Cys)3-ligated-type", "eco_id": "ECO_0000259", "start_pos": 108, "end_pos": 147, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" }, { "id": "PS51669", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51669" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "4Fe-4S Mo/W bis-MGD-type", "eco_id": "ECO_0000259", "start_pos": 245, "end_pos": 301, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9#function" }, { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" }, { "id": "7W4Q", "database": "PDB", "url": "https://www.rcsb.org/structure/7W4Q" }, { "id": "7W00", "database": "PDB", "url": "https://www.rcsb.org/structure/7W00" }, { "id": "7W1O", "database": "PDB", "url": "https://www.rcsb.org/structure/7W1O" }, { "id": "7W4N", "database": "PDB", "url": "https://www.rcsb.org/structure/7W4N" }, { "id": "7V2K", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2K" }, { "id": "7V3M", "database": "PDB", "url": "https://www.rcsb.org/structure/7V3M" } ], "binding_site_uniprot": 133, "amino_acid": "Gln", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0007829", "start_pos": 133, "end_pos": 133, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9#function" }, { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" }, { "id": "7W1O", "database": "PDB", "url": "https://www.rcsb.org/structure/7W1O" }, { "id": "7V2D", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2D" }, { "id": "7V30", "database": "PDB", "url": "https://www.rcsb.org/structure/7V30" }, { "id": "7W4M", "database": "PDB", "url": "https://www.rcsb.org/structure/7W4M" }, { "id": "7V2E", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2E" }, { "id": "7VB7", "database": "PDB", "url": "https://www.rcsb.org/structure/7VB7" }, { "id": "7V31", "database": "PDB", "url": "https://www.rcsb.org/structure/7V31" }, { "id": "7VYF", "database": "PDB", "url": "https://www.rcsb.org/structure/7VYF" } ], "binding_site_uniprot": 223, "amino_acid": "Ile", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "2", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0007829", "start_pos": 223, "end_pos": 223, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9#function" }, { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" }, { "id": "7W4F", "database": "PDB", "url": "https://www.rcsb.org/structure/7W4F" }, { "id": "7W2U", "database": "PDB", "url": "https://www.rcsb.org/structure/7W2U" }, { "id": "7W1O", "database": "PDB", "url": "https://www.rcsb.org/structure/7W1O" }, { "id": "7W4M", "database": "PDB", "url": "https://www.rcsb.org/structure/7W4M" }, { "id": "7V2E", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2E" }, { "id": "7VB7", "database": "PDB", "url": "https://www.rcsb.org/structure/7VB7" }, { "id": "8ZSK", "database": "PDB", "url": "https://www.rcsb.org/structure/8ZSK" } ], "binding_site_uniprot": 226, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "10", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0007829", "start_pos": 226, "end_pos": 226, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9#function" }, { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" }, { "id": "7W4F", "database": "PDB", "url": "https://www.rcsb.org/structure/7W4F" }, { "id": "7W2U", "database": "PDB", "url": "https://www.rcsb.org/structure/7W2U" }, { "id": "7V2F", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2F" }, { "id": "7V2H", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2H" }, { "id": "7V2R", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2R" }, { "id": "7V2C", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2C" }, { "id": "7W4N", "database": "PDB", "url": "https://www.rcsb.org/structure/7W4N" }, { "id": "7V2K", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2K" }, { "id": "7V3M", "database": "PDB", "url": "https://www.rcsb.org/structure/7V3M" }, { "id": "7V2E", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2E" }, { "id": "7VB7", "database": "PDB", "url": "https://www.rcsb.org/structure/7VB7" } ], "binding_site_uniprot": 228, "amino_acid": "Val", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "10", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0007829", "start_pos": 228, "end_pos": 228, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9#function" }, { "id": "A0A4X1V1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V1H9" }, { "id": "7V2R", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2R" }, { "id": "7V2C", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2C" }, { "id": "7W4K", "database": "PDB", "url": "https://www.rcsb.org/structure/7W4K" }, { "id": "8ZO8", "database": "PDB", "url": "https://www.rcsb.org/structure/8ZO8" }, { "id": "7V2K", "database": "PDB", "url": "https://www.rcsb.org/structure/7V2K" }, { "id": "7V3M", "database": "PDB", "url": "https://www.rcsb.org/structure/7V3M" }, { "id": "7VY8", "database": "PDB", "url": "https://www.rcsb.org/structure/7VY8" }, { "id": "7V31", "database": "PDB", "url": "https://www.rcsb.org/structure/7V31" }, { "id": "7VYF", "database": "PDB", "url": "https://www.rcsb.org/structure/7VYF" } ], "binding_site_uniprot": 231, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "12", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0007829", "start_pos": 231, "end_pos": 231, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 374, 611 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 388, "end_pos": 390 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U3N9-1", "uniprot_ac": "A0A4X1U3N9", "uniprot_id": "A0A4X1U3N9_PIG", "mass": { "chemical_mass": 34569.0, "monoisotopic_mass": 34569.0 }, "refseq": {}, "gene_names": [ { "name": "RPL5", "type": "recommended", "evidence": [ { "id": "A0A4X1U3N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL18", "type": "recommended", "evidence": [ { "id": "A0A4X1U3N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L5", "type": "synonym", "evidence": [ { "id": "A0A4X1U3N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3N9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9", "locus": { "chromosome": "4", "start_pos": 124358594, "end_pos": 124367645, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006899", "url": "https://www.ensembl.org/id/ENSSSCG00000006899" } ] } } ], "crossref": [ { "id": "A0A4X1U3N9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U3N9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006899", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006899", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00432", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00432", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "3J7O", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=3J7O&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "3J7P", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=3J7P&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "3J7Q", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=3J7Q&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "3J7R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=3J7R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR005485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CQIASAH", "url": "https://omabrowser.org/oma/group/CQIASAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23410", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23410", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23410:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23410:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00003j7o", "url": "https://www.rcsb.org/structure/pdb_00003j7o", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00003j7p", "url": "https://www.rcsb.org/structure/pdb_00003j7p", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00003j7q", "url": "https://www.rcsb.org/structure/pdb_00003j7q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00003j7r", "url": "https://www.rcsb.org/structure/pdb_00003j7r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "3J7O", "url": "https://www.rcsb.org/structure/3J7O", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "3J7P", "url": "https://www.rcsb.org/structure/3J7P", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "3J7Q", "url": "https://www.rcsb.org/structure/3J7Q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "3J7R", "url": "https://www.rcsb.org/structure/3J7R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF14204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14204", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287ASD0", "url": "https://www.uniprot.org/uniprotkb/A0A287ASD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ASD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TYB5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TYB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U3N9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U3N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0MVZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MVZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0MVZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MVZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHILGQNVADYMRYLIEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES", "length": 299, "header": "tr|A0A4X1U3N9-1|A0A4X1U3N9_PIG Isoform 1 of Large ribosomal subunit protein uL18 OS=Sus scrofa OX=9823 GN=RPL5 PE=1 SV=1 CANONICAL=A0A4X1U3N9-1" }, "isoforms": [ { "isoform_ac": "A0A287ASD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9/entry#A0A287ASD0-1", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHILGQNVADYMRYLIEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES", "length": 297, "header": "tr|A0A287ASD0-1|A0A4X1U3N9_PIG Computationally mapped isoform of Large ribosomal subunit protein uL18 OS=Sus scrofa OX=9823 GN=RPL5 PE=1 SV=1 CANONICAL=A0A4X1U3N9-1" }, "locus": { "chromosome": "4", "start_pos": 124367568, "end_pos": 124359856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040918.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040918.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046769.1", "url": "https://www.ensembl.org/id/ENSSSCP00000046769.1" } ] } }, { "isoform_ac": "A0A4X1TYB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9/entry#A0A4X1TYB5-1", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES", "length": 170, "header": "tr|A0A4X1TYB5-1|A0A4X1TYB5_PIG Computationally mapped isoform of Large ribosomal subunit protein uL18 OS=Sus scrofa OX=9823 GN=RPL5 PE=1 SV=1 CANONICAL=A0A4X1U3N9-1" }, "locus": { "chromosome": "4", "start_pos": 124367568, "end_pos": 124359856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085097.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085097.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065449.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065449.1" } ] } }, { "isoform_ac": "A0A4X1U3N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9/entry#A0A4X1U3N9-1", "sequence": { "sequence": "MSKGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHILGQNVADYMRYLIEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES", "length": 299, "header": "tr|A0A4X1U3N9-1|A0A4X1U3N9_PIG Isoform 1 of Large ribosomal subunit protein uL18 OS=Sus scrofa OX=9823 GN=RPL5 PE=1 SV=1 CANONICAL=A0A4X1U3N9-1" }, "locus": { "chromosome": "4", "start_pos": 124366529, "end_pos": 124359856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067358.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067358.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067120.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067120.1" } ] } }, { "isoform_ac": "A0A8D0MVZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9/entry#A0A8D0MVZ5-1", "sequence": { "sequence": "MSKGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHILGQNVADYMRYLIEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES", "length": 254, "header": "tr|A0A8D0MVZ5-1|A0A4X1U3N9_PIG Computationally mapped isoform of Large ribosomal subunit protein uL18 OS=Sus scrofa OX=9823 GN=RPL5 PE=1 SV=1 CANONICAL=A0A4X1U3N9-1" }, "locus": { "chromosome": "4", "start_pos": 124366529, "end_pos": 124359856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007554.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007554.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007354.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007354.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Structure of the mammalian ribosome-Sec61 complex to 3.4 A resolution.", "journal": "Cell", "date": "2014", "authors": "Voorhees Rebecca M, Fern\u00e1ndez Israel S, Scheres Sjors H W, Hegde Ramanujan S", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0MVZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MVZ5" } ], "reference": [ { "type": "PubMed", "id": "24930395", "url": "https://glygen.org/publication/PubMed/24930395" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0MVZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MVZ5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "P22451-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "RPL5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNKFGLDKIYEGQVEVTGDEYNVESVDGKPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNITPDGMEEMYKKAHAAIRDNPVHEKKPKREVKKKRVNSTKMSLAQKKDRVAQKKASFLRAQERAADS", "length": 297 }, "evidence": [ { "id": "A0A4X1U3N9", "url": "https://omabrowser.org/oma/group/A0A4X1U3N9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P46777-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "RPL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNSVTPDMMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES", "length": 297 }, "evidence": [ { "id": "A0A4X1U3N9", "url": "https://omabrowser.org/oma/group/A0A4X1U3N9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47962-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "Rpl5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVRFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVNGGEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES", "length": 297 }, "evidence": [ { "id": "A0A4X1U3N9", "url": "https://omabrowser.org/oma/group/A0A4X1U3N9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49227-1", "protein_name": "Large ribosomal subunit protein uL18y", "gene_name": "RPL5B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVFVKSSKSNAYFKRYQVKFRRRRDGKTDYRARIRLINQDKNKYNTPKYRFVVRFTNKDIVAQIVSASIAGDIVKASAYAHELPQYGLTVGLTNYAAAYCTGLLLARRVLKMLEMDDEYEGNVEATGEDFSVEPTDSRRPFRALLDVGLIRTTTGNRVFGALKGALDGGLDIPHSDKRFAGFHKENKQLDAEIHRNYIYGGHVSNYMKLLGEDEPEKLQTHFSAYIKKGVEAESIEEMYKKVHAAIRAEPNHKKTEKSAPKEHKRYNLKKLTYEERKNKLIERVKALNGAGGDDDDEDDEE", "length": 301 }, "evidence": [ { "id": "A0A4X1U3N9", "url": "https://omabrowser.org/oma/group/A0A4X1U3N9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q54XX3-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "rpl5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGFVKVVKTKAYYSRYQVQFRRRREGKTDYQQRHRLITQDKNKYNSPKYRLVARITNTDVIAQVVYSKIVGDFVLCAAYAHELPRFGVKVGLTNYASCYATGLLLARRLLAKLKLADLYKGAEKVDGKVFLVKPVDDKPRPFKANLDVGLARTSTGAKVFAVLKGAVDGGIYVPHGETRFAGYNAESKKLNAETLRGYIFGKHVASYMTLLQTEDEDAYKKIFSQYIKNGVAPKDIETIYANAHKAIRANPAPAAKSTKSYKDIKSKNLSKRTLKQKKARVASIKASYKARL", "length": 292 }, "evidence": [ { "id": "A0A4X1U3N9", "url": "https://omabrowser.org/oma/group/A0A4X1U3N9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q58DW5-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "RPL5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLIEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES", "length": 297 }, "evidence": [ { "id": "A0A4X1U3N9", "url": "https://omabrowser.org/oma/group/A0A4X1U3N9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3N9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3N9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3N9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3N9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3N9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3N9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3N9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" } ], "pmid": "" }, { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3N9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "5S rRNA binding", "id": "GO:0008097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008097", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3N9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3N9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U3N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3N9" }, { "id": "PF14204", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14204" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL18 C-terminal eukaryotes", "eco_id": "ECO_0000259", "start_pos": 238, "end_pos": 291, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UZS4-1", "uniprot_ac": "A0A4X1UZS4", "uniprot_id": "A0A4X1UZS4_PIG", "mass": { "chemical_mass": 36000.0, "monoisotopic_mass": 36000.0 }, "refseq": {}, "gene_names": [ { "name": "PITX2", "type": "recommended", "evidence": [ { "id": "A0A4X1UZS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ] } ], "protein_names": [ { "name": "Homeobox protein", "type": "recommended", "evidence": [ { "id": "A0A4X1UZS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PITX2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4", "locus": { "chromosome": "8", "start_pos": 111723298, "end_pos": 111698757, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034708", "url": "https://www.ensembl.org/id/ENSSSCG00000034708" } ] } } ], "crossref": [ { "id": "A0A4X1UZS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UZS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034708", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034708", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515395", "url": "https://www.ncbi.nlm.nih.gov/gene/100515395", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016233", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016233", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NSMRNPL", "url": "https://omabrowser.org/oma/group/NSMRNPL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR45882", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45882", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45882:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45882:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AUF8", "url": "https://www.uniprot.org/uniprotkb/A0A287AUF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AUF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AUF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UZS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7H1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNCMKGPLHLEHRAAGTKLLAVSSSSSSCHHPQPLAMASVLAPGQTRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 326, "header": "tr|A0A4X1UZS4-1|A0A4X1UZS4_PIG Isoform 1 of Homeobox protein OS=Sus scrofa OX=9823 GN=PITX2 PE=3 SV=1 CANONICAL=A0A4X1UZS4-1" }, "isoforms": [ { "isoform_ac": "A0A287AUF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4/entry#A0A287AUF8-1", "sequence": { "sequence": "METNCRKLVSACVQLEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 271, "header": "tr|A0A287AUF8-1|A0A4X1UZS4_PIG Computationally mapped isoform of Homeobox protein OS=Sus scrofa OX=9823 GN=PITX2 PE=3 SV=1 CANONICAL=A0A4X1UZS4-1" }, "locus": { "chromosome": "8", "start_pos": 111722602, "end_pos": 111707716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058997.1", "url": "https://www.ensembl.org/id/ENSSSCT00000058997.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047560.1", "url": "https://www.ensembl.org/id/ENSSSCP00000047560.1" } ] } }, { "isoform_ac": "A0A4X1UZS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4/entry#A0A4X1UZS4-1", "sequence": { "sequence": "MNCMKGPLHLEHRAAGTKLLAVSSSSSSCHHPQPLAMASVLAPGQTRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 326, "header": "tr|A0A4X1UZS4-1|A0A4X1UZS4_PIG Isoform 1 of Homeobox protein OS=Sus scrofa OX=9823 GN=PITX2 PE=3 SV=1 CANONICAL=A0A4X1UZS4-1" }, "locus": { "chromosome": "8", "start_pos": 111722602, "end_pos": 111718372, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053647.2", "url": "https://www.ensembl.org/id/ENSSSCT00000053647.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050328.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050328.1" } ] } }, { "isoform_ac": "A0A5G2R7H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4/entry#A0A5G2R7H1-1", "sequence": { "sequence": "METNCRKLVSACVQLGVQPAAVECLFSKDSDIKKVEFTDSPESRKEAASSKLFPRQHPGASEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 317, "header": "tr|A0A5G2R7H1-1|A0A4X1UZS4_PIG Computationally mapped isoform of Homeobox protein OS=Sus scrofa OX=9823 GN=PITX2 PE=3 SV=1 CANONICAL=A0A4X1UZS4-1" }, "locus": { "chromosome": "8", "start_pos": 111722602, "end_pos": 111707716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089235.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089235.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072291.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072291.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 268, "start_aa": "Thr", "end_pos": 268, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr268", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 277, "start_aa": "Thr", "end_pos": 277, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr277", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AUF8", "url": "https://www.uniprot.org/uniprotkb/A0A287AUF8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P1S6-1", "protein_name": "Homeobox protein", "gene_name": "PITX2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSCMKDPLSLERLGAGNNKLCSSSPSSSSSSSSCHHQQPALAMATALAPGQARSSLEAAKHRLEVHTISDTSSPEAAEKEKSQQGKSEDAGPEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSGLNSLNNLNNLSNPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 333 }, "evidence": [ { "id": "A0A4X1UZS4", "url": "https://omabrowser.org/oma/group/A0A4X1UZS4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P97474-1", "protein_name": "Pituitary homeobox 2", "gene_name": "Pitx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METNCRKLVSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPKSRKESASSKLFPRQHPGANEKDKGQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 317 }, "evidence": [ { "id": "A0A4X1UZS4", "url": "https://omabrowser.org/oma/group/A0A4X1UZS4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99697-1", "protein_name": "Pituitary homeobox 2", "gene_name": "PITX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METNCRKLVSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 317 }, "evidence": [ { "id": "A0A4X1UZS4", "url": "https://omabrowser.org/oma/group/A0A4X1UZS4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R0W1-1", "protein_name": "Pituitary homeobox 2", "gene_name": "Pitx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCMKGPLPLEHRAAGTKLSAASSPFCHHTQALAMASVLAPGQPRSLDASKHRLEVHTISDTSSPEVAEKDKGQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 324 }, "evidence": [ { "id": "A0A4X1UZS4", "url": "https://omabrowser.org/oma/group/A0A4X1UZS4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9W5Z2-1", "protein_name": "Pituitary homeobox 2", "gene_name": "pitx2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSMKDPLSLDHHHHNHHVTGSKHAPLSMASSLQPLQRSVDSKHRLDVHTVSDTSSPESVEKEKGQSKNEDSNDDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPSYTYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQTMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSNPSLNSGVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV", "length": 314 }, "evidence": [ { "id": "A0A4X1UZS4", "url": "https://omabrowser.org/oma/group/A0A4X1UZS4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "embryonic heart tube left/right pattern formation", "id": "GO:0060971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060971", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "spleen development", "id": "GO:0048536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048536", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "odontogenesis", "id": "GO:0042476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042476", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "left/right axis specification", "id": "GO:0070986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070986", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "deltoid tuberosity development", "id": "GO:0035993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035993", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "cardiac neural crest cell migration involved in outflow tract morphogenesis", "id": "GO:0003253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003253", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "iris morphogenesis", "id": "GO:0061072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061072", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UZS4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UZS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 152, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1UZS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZS4" }, { "id": "PS50803", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50803" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OAR", "eco_id": "ECO_0000259", "start_pos": 288, "end_pos": 301, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 268, 277 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 314, "end_pos": 316 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UN51-1", "uniprot_ac": "A0A4X1UN51", "uniprot_id": "A0A4X1UN51_PIG", "mass": { "chemical_mass": 12806.0, "monoisotopic_mass": 12806.0 }, "refseq": {}, "gene_names": [ { "name": "SRP14", "type": "recommended", "evidence": [ { "id": "A0A4X1UN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51" } ] } ], "protein_names": [ { "name": "Signal recognition particle 14 kDa protein", "type": "recommended", "evidence": [ { "id": "A0A4X1UN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51/entry#names_and_taxonomy" } ] }, { "name": "SRP14", "type": "synonym", "evidence": [ { "id": "A0A4X1UN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIZ0#function" }, { "database": "UniProtKB", "id": "RU368100", "url": "https://www.uniprot.org/uniprotkb/RU368100#function" }, { "database": "UniProtKB", "id": "ARBA00045462", "url": "https://www.uniprot.org/uniprotkb/ARBA00045462#function" }, { "database": "UniProtKB", "id": "A0A8W4FHT9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHT9#function" }, { "database": "UniProtKB", "id": "A0A4X1UN51", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51#function" }, { "database": "UniProtKB", "id": "A0A287AZ76", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ76#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UN51", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SRP14", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51", "locus": { "chromosome": "1", "start_pos": 131253411, "end_pos": 131241612, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004785", "url": "https://www.ensembl.org/id/ENSSSCG00000004785" } ] } } ], "crossref": [ { "id": "A0A4X1UN51", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UN51", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004785", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004785", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12013", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12013", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02290", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02290", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AZ76", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AZ76-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UN51", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UN51-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FHT9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FHT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLLESEQFLTELTRLFQKCRLSGSVFITLKKYDGRTKPIPRKGSVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMVSFGCSLSPPSQGKSQHNIHWVRLLFRFTALL", "length": 113, "header": "tr|A0A4X1UN51-1|A0A4X1UN51_PIG Isoform 1 of Signal recognition particle 14 kDa protein OS=Sus scrofa OX=9823 GN=SRP14 PE=1 SV=1 CANONICAL=A0A4X1UN51-1" }, "isoforms": [ { "isoform_ac": "A0A287AZ76-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51/entry#A0A287AZ76-1", "sequence": { "sequence": "MVLLESEQFLTELTRLFQKCRLSGSVFITLKKYDGRTKPIPRKGSVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLLHVVHSSGNRLASRCC", "length": 102, "header": "tr|A0A287AZ76-1|A0A4X1UN51_PIG Computationally mapped isoform of Signal recognition particle 14 kDa protein OS=Sus scrofa OX=9823 GN=SRP14 PE=1 SV=1 CANONICAL=A0A4X1UN51-1" }, "locus": { "chromosome": "1", "start_pos": 131248587, "end_pos": 131241678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053992.2", "url": "https://www.ensembl.org/id/ENSSSCT00000053992.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049446.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049446.2" } ] } }, { "isoform_ac": "A0A4X1UN51-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51/entry#A0A4X1UN51-1", "sequence": { "sequence": "MVLLESEQFLTELTRLFQKCRLSGSVFITLKKYDGRTKPIPRKGSVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMVSFGCSLSPPSQGKSQHNIHWVRLLFRFTALL", "length": 113, "header": "tr|A0A4X1UN51-1|A0A4X1UN51_PIG Isoform 1 of Signal recognition particle 14 kDa protein OS=Sus scrofa OX=9823 GN=SRP14 PE=1 SV=1 CANONICAL=A0A4X1UN51-1" }, "locus": { "chromosome": "1", "start_pos": 131244267, "end_pos": 131241678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072740.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072740.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065556.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065556.1" } ] } }, { "isoform_ac": "A0A8W4FHT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51/entry#A0A8W4FHT9-1", "sequence": { "sequence": "MVLLESEQFLTELTRLFQKCRLSGSVFITLKKYDGRTKPIPRKGSVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMVSFGCSLSPPSQGKSQFTALL", "length": 102, "header": "tr|A0A8W4FHT9-1|A0A4X1UN51_PIG Computationally mapped isoform of Signal recognition particle 14 kDa protein OS=Sus scrofa OX=9823 GN=SRP14 PE=1 SV=1 CANONICAL=A0A4X1UN51-1" }, "locus": { "chromosome": "1", "start_pos": 131244267, "end_pos": 131241678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103881.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103881.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078797.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078797.1" } ] } }, { "isoform_ac": "A0A8W4FIZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51/entry#A0A8W4FIZ0-1", "sequence": { "sequence": "MVLLESEQFLTELTRLFQKCRLSGSVFITLKKYDGRTKPIPRKGSVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMLYRFRLHVVHSSGNRLASRCC", "length": 102, "header": "tr|A0A8W4FIZ0-1|A0A4X1UN51_PIG Computationally mapped isoform of Signal recognition particle 14 kDa protein OS=Sus scrofa OX=9823 GN=SRP14 PE=1 SV=1 CANONICAL=A0A4X1UN51-1" }, "locus": { "chromosome": "1", "start_pos": 131248587, "end_pos": 131241678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092110.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092110.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078278.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078278.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FHT9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHT9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "signal recognition particle, endoplasmic reticulum targeting", "id": "GO:0005786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005786", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UN51", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UN51", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum signal peptide binding", "id": "GO:0030942", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030942", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UN51", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51" } ], "pmid": "" }, { "name": "7S RNA binding", "id": "GO:0008312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008312", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UN51", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UN51", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51" } ], "pmid": "" }, { "name": "protein targeting to ER", "id": "GO:0045047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045047", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UN51", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UN51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1V568-1", "uniprot_ac": "A0A4X1V568", "uniprot_id": "A0A4X1V568_PIG", "mass": { "chemical_mass": 61488.0, "monoisotopic_mass": 61488.0 }, "refseq": { "ac": "XP_003124017", "name": "kelch-like protein 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124017" }, "gene_names": [ { "name": "KLHL3", "type": "recommended", "evidence": [ { "id": "A0A4X1V568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ] }, { "name": "KLHL3", "type": "synonym", "evidence": [ { "id": "XP_003124017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124017" } ] } ], "protein_names": [ { "name": "Kelch-like protein 3", "type": "recommended", "evidence": [ { "id": "A0A4X1V568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_003124017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124017" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KLHL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568", "locus": { "chromosome": "2", "start_pos": 139632869, "end_pos": 139920497, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014321", "url": "https://www.ensembl.org/id/ENSSSCG00000014321" } ] } } ], "crossref": [ { "id": "A0A4X1V568", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1V568", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014321", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014321", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18339", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18339", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18513", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18513", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519539", "url": "https://www.ncbi.nlm.nih.gov/gene/100519539", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519539", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519539", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EVPAHKN", "url": "https://omabrowser.org/oma/group/EVPAHKN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1V568", "url": "https://www.orthodb.org/?gene=A0A4X1V568", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003124017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124017", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B601", "url": "https://www.uniprot.org/uniprotkb/A0A287B601", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B601-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B601-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V568-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKAFKVMNELRSKQLLCDVMIVAEDVEIEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEDRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWTYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKPL", "length": 555, "header": "tr|A0A4X1V568-1|A0A4X1V568_PIG Isoform 1 of Kelch-like protein 3 OS=Sus scrofa OX=9823 GN=KLHL3 PE=3 SV=1 CANONICAL=A0A4X1V568-1" }, "isoforms": [ { "isoform_ac": "A0A287B601-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568/entry#A0A287B601-1", "sequence": { "sequence": "MQSSAATTPAGPRTMEGESIKPSSQLPIQPGEDEKNHRTITVNPAHMGKAFKVMNELRSKQLLCDVMIVAEDVEIEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEDRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWTYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKPL", "length": 601, "header": "tr|A0A287B601-1|A0A4X1V568_PIG Computationally mapped isoform of Kelch-like protein 3 OS=Sus scrofa OX=9823 GN=KLHL3 PE=3 SV=2 CANONICAL=A0A4X1V568-1" }, "locus": { "chromosome": "2", "start_pos": 139751231, "end_pos": 139637293, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040784.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040784.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051511.2", "url": "https://www.ensembl.org/id/ENSSSCP00000051511.2" } ] } }, { "isoform_ac": "A0A4X1V568-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568/entry#A0A4X1V568-1", "sequence": { "sequence": "MGKAFKVMNELRSKQLLCDVMIVAEDVEIEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEDRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWTYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKPL", "length": 555, "header": "tr|A0A4X1V568-1|A0A4X1V568_PIG Isoform 1 of Kelch-like protein 3 OS=Sus scrofa OX=9823 GN=KLHL3 PE=3 SV=1 CANONICAL=A0A4X1V568-1" }, "locus": { "chromosome": "2", "start_pos": 139736832, "end_pos": 139637293, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043401.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043401.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042768.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042768.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B601", "url": "https://www.uniprot.org/uniprotkb/A0A287B601" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519539", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519539", "resource": "KEGG Pathway" }, { "id": "R-SSC-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "E0CZ16-1", "protein_name": "Kelch-like protein 3", "gene_name": "Klhl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGESVKPSPQPTAQAEDEEKNRRTVTVNAAHMGKAFKVMNELRSKRLLCDVMIVAEDVEVEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLDHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEGRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL", "length": 587 }, "evidence": [ { "id": "A0A4X1V568", "url": "https://omabrowser.org/oma/group/A0A4X1V568/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MBP6-1", "protein_name": "Kelch-like protein 3", "gene_name": "KLHL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDGESIKPSSQPLIQTGDDEKNQRTITVNPAHMGKAFKVMNELRSKQLLCDVMIVAEDVEIEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEDRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWTYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKPL", "length": 587 }, "evidence": [ { "id": "A0A4X1V568", "url": "https://omabrowser.org/oma/group/A0A4X1V568/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9UH77-1", "protein_name": "Kelch-like protein 3", "gene_name": "KLHL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGESVKLSSQTLIQAGDDEKNQRTITVNPAHMGKAFKVMNELRSKQLLCDVMIVAEDVEIEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEDRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL", "length": 587 }, "evidence": [ { "id": "A0A4X1V568", "url": "https://omabrowser.org/oma/group/A0A4X1V568/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" }, { "name": "cullin family protein binding", "id": "GO:0097602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097602", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" }, { "name": "monoatomic ion homeostasis", "id": "GO:0050801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050801", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" }, { "name": "renal sodium ion absorption", "id": "GO:0070294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070294", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" }, { "name": "distal tubule morphogenesis", "id": "GO:0072156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072156", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V568", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1V568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V568" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 85, "start_aa": "Cys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 538, "end_pos": 540 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UWJ9-1", "uniprot_ac": "A0A4X1UWJ9", "uniprot_id": "A0A4X1UWJ9_PIG", "mass": { "chemical_mass": 95424.0, "monoisotopic_mass": 95424.0 }, "refseq": {}, "gene_names": [ { "name": "HSPA4", "type": "recommended", "evidence": [ { "id": "A0A4X1UWJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ] } ], "protein_names": [ { "name": "Heat shock 70 kDa protein 4", "type": "recommended", "evidence": [ { "id": "A0A4X1UWJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HSPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9", "locus": { "chromosome": "2", "start_pos": 135391108, "end_pos": 135345867, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014292", "url": "https://www.ensembl.org/id/ENSSSCG00000014292" } ] } } ], "crossref": [ { "id": "A0A4X1UWJ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UWJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014292", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014292", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11737", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11737", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR013126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45639:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45639:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27508", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27508", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3371453", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B6J6", "url": "https://www.uniprot.org/uniprotkb/A0A287B6J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B6J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B6J6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UWJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0T1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0T1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RI15", "url": "https://www.uniprot.org/uniprotkb/F1RI15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RI15-1", "url": "https://www.uniprot.org/uniprotkb/F1RI15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNTVQGFKRFHGRAFSDPFVEAEKSKLAYDIVQLPTGLTGIKVKYMEEERNFTTEQVTAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSSYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNRGKFLEMCDDLLARVEPPLRSVLEQARLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVFSKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKFEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAETEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNTFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKVISSFKNKEDQYDHLDAADMVKVEKSMNEAMEWMNNKLNLQNKQSLTVDPVVKAKEIEAKIKELTNICNPIISKPKPKVEPPKEEQKNAEQNGPVDGQGDSPGPQASEQGAPMTNATCCSWEHAPFHLEQVNGGFWA", "length": 848, "header": "tr|A0A4X1UWJ9-1|A0A4X1UWJ9_PIG Isoform 1 of Heat shock 70 kDa protein 4 OS=Sus scrofa OX=9823 GN=HSPA4 PE=1 SV=1 CANONICAL=A0A4X1UWJ9-1" }, "isoforms": [ { "isoform_ac": "A0A287B6J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9/entry#A0A287B6J6-1", "sequence": { "sequence": "MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNTVQGFKRFHGRAFSDPFVEAEKSKLAYDIVQLPTGLTGIKVKYMEEERNFTTEQVTAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSSYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNRGKFLEMCDDLLARVEPPLRSVLEQARLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVFSKNHAAPFSKVLTFYRKEPFTLEAYYSSRSFVFHMSLAQFSVQKVLLSLMAPVQK", "length": 475, "header": "tr|A0A287B6J6-1|A0A4X1UWJ9_PIG Computationally mapped isoform of Heat shock 70 kDa protein 4 OS=Sus scrofa OX=9823 GN=HSPA4 PE=1 SV=2 CANONICAL=A0A4X1UWJ9-1" }, "locus": { "chromosome": "2", "start_pos": 135378091, "end_pos": 135346077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047672.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047672.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052080.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052080.2" } ] } }, { "isoform_ac": "A0A4X1UWJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9/entry#A0A4X1UWJ9-1", "sequence": { "sequence": "MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNTVQGFKRFHGRAFSDPFVEAEKSKLAYDIVQLPTGLTGIKVKYMEEERNFTTEQVTAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSSYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNRGKFLEMCDDLLARVEPPLRSVLEQARLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVFSKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKFEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAETEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNTFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKVISSFKNKEDQYDHLDAADMVKVEKSMNEAMEWMNNKLNLQNKQSLTVDPVVKAKEIEAKIKELTNICNPIISKPKPKVEPPKEEQKNAEQNGPVDGQGDSPGPQASEQGAPMTNATCCSWEHAPFHLEQVNGGFWA", "length": 848, "header": "tr|A0A4X1UWJ9-1|A0A4X1UWJ9_PIG Isoform 1 of Heat shock 70 kDa protein 4 OS=Sus scrofa OX=9823 GN=HSPA4 PE=1 SV=1 CANONICAL=A0A4X1UWJ9-1" }, "locus": { "chromosome": "2", "start_pos": 135389813, "end_pos": 135346077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075742.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075742.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073845.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073845.2" } ] } }, { "isoform_ac": "A0A5G2R0T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9/entry#A0A5G2R0T1-1", "sequence": { "sequence": "VEGQNHRLALACISFGPKNRSIGAAAKSQVISNAKNTVQGFKRFHGRAFSDPFVEAEKSKLAYDIVQLPTGLTGIKVKYMEEERNFTTEQVTAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSSYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNRGKFLEMCDDLLARVEPPLRSVLEQARLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVFSKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKFEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAETEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNTFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKVISSFKNKEDQYDHLDAADMVKVEKSMNEAMEWMNNKLNLQNKQSLTVDPVVKAKEIEAKIKELTNICNPIISKPKPKVEPPKEEQKNAEQNGPVDGQGDSPGPQASEQGTDTAVPSDSDKKLPEMDID", "length": 814, "header": "tr|A0A5G2R0T1-1|A0A4X1UWJ9_PIG Computationally mapped isoform of Heat shock 70 kDa protein 4 OS=Sus scrofa OX=9823 GN=HSPA4 PE=1 SV=2 CANONICAL=A0A4X1UWJ9-1" }, "locus": { "chromosome": "2", "start_pos": 135389156, "end_pos": 135356591, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078822.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078822.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070770.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070770.2" } ] } }, { "isoform_ac": "F1RI15-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9/entry#F1RI15-1", "sequence": { "sequence": "MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNTVQGFKRFHGRAFSDPFVEAEKSKLAYDIVQLPTGLTGIKVKYMEEERNFTTEQVTAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSSYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNRGKFLEMCDDLLARVEPPLRSVLEQARLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVFSKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKFEENEEPMETDQNAKEEETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNTFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKVISSFKNKEDQYDHLDAADMVKVEKSMNEAMEWMNNKLNLQNKQSLTVDPVVKAKEIEAKIKELTNICNPIISKPKPKVEPPKEEQKNAEQNGPVDGQGDSPGPQASEQGTDTAVPSDSDKKLPEMDID", "length": 810, "header": "tr|F1RI15-1|A0A4X1UWJ9_PIG Computationally mapped isoform of Heat shock 70 kDa protein 4 OS=Sus scrofa OX=9823 GN=HSPA4 PE=1 SV=3 CANONICAL=A0A4X1UWJ9-1" }, "locus": { "chromosome": "2", "start_pos": 135389156, "end_pos": 135346077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015615.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015615.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015203.4", "url": "https://www.ensembl.org/id/ENSSSCP00000015203.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0T1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0T1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3371453", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "resource": "Reactome", "description": "Regulation of HSF1-mediated heat shock response" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ], "pmid": "" }, { "name": "adenyl-nucleotide exchange factor activity", "id": "GO:0000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000774", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ], "pmid": "" }, { "name": "organelle", "id": "GO:0043226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043226", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ], "pmid": "" }, { "name": "chaperone-mediated protein complex assembly", "id": "GO:0051131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051131", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UWJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 826, "end_pos": 828 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U9U9-1", "uniprot_ac": "A0A4X1U9U9", "uniprot_id": "A0A4X1U9U9_PIG", "mass": { "chemical_mass": 43580.0, "monoisotopic_mass": 43580.0 }, "refseq": { "ac": "XP_005657493", "name": "probable palmitoyltransferase ZDHHC16 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657493" }, "gene_names": [ { "name": "ZDHHC16", "type": "recommended", "evidence": [ { "id": "A0A4X1U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9" } ] }, { "name": "ZDHHC16", "type": "synonym", "evidence": [ { "id": "XP_005657493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657493" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "A0A4X1U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "A0A4X1U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9/entry#names_and_taxonomy" } ] }, { "name": "probable palmitoyltransferase ZDHHC16 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005657493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657493" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9U9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZDHHC16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9", "locus": { "chromosome": "14", "start_pos": 108852789, "end_pos": 108842966, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010519", "url": "https://www.ensembl.org/id/ENSSSCG00000010519" } ] } } ], "crossref": [ { "id": "A0A4X1U9U9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U9U9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010519", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010519", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152371", "url": "https://www.ncbi.nlm.nih.gov/gene/100152371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152371", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DGIVWDC", "url": "https://omabrowser.org/oma/group/DGIVWDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287B8T5", "url": "https://www.orthodb.org/?gene=A0A287B8T5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U9U9", "url": "https://www.orthodb.org/?gene=A0A4X1U9U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8D1EJ15", "url": "https://www.orthodb.org/?gene=A0A8D1EJ15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005657493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657493", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B8T5", "url": "https://www.uniprot.org/uniprotkb/A0A287B8T5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B8T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B8T5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U9U9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U9U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UCV1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UCV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1EJ15", "url": "https://www.uniprot.org/uniprotkb/A0A8D1EJ15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1EJ15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1EJ15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGQRSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPIYWLVDNVIRWCGVVFVVLVIVLTSSIVAIAYLCVLPLILQTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDITTVSICKKCINPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIEKMKQLDKNKLQAVANQTYHQTPPPTFSFRERVTHKSLVYLWFLCSSVALALGALTVWHAVLISRGETSIERHINKKERRRLQAKGRVFRNHYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWDPPPWVTAHSASVMAV", "length": 377, "header": "tr|A0A4X1U9U9-1|A0A4X1U9U9_PIG Isoform 1 of Palmitoyltransferase OS=Sus scrofa OX=9823 GN=ZDHHC16 PE=3 SV=1 CANONICAL=A0A4X1U9U9-1" }, "isoforms": [ { "isoform_ac": "A0A287B8T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9/entry#A0A287B8T5-1", "sequence": { "sequence": "MRGQRSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPIYWLVDNVIRWCGVVFVVLVIVLTSSIVAIAYLCVLPLILQTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDITTVSICKKCINPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIETYHQTPPPTFSFRERVTHKSLVYLWFLCSSVALALGALTVWHAVLISRGETSIERHINKKERRRLQAKGRVFRNHYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWDPPPWVTAHSASVMAV", "length": 361, "header": "tr|A0A287B8T5-1|A0A4X1U9U9_PIG Computationally mapped isoform of Palmitoyltransferase OS=Sus scrofa OX=9823 GN=ZDHHC16 PE=3 SV=1 CANONICAL=A0A4X1U9U9-1" }, "locus": { "chromosome": "14", "start_pos": 108852318, "end_pos": 108846932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046583.2", "url": "https://www.ensembl.org/id/ENSSSCT00000046583.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052936.1", "url": "https://www.ensembl.org/id/ENSSSCP00000052936.1" } ] } }, { "isoform_ac": "A0A4X1U9U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9/entry#A0A4X1U9U9-1", "sequence": { "sequence": "MRGQRSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPIYWLVDNVIRWCGVVFVVLVIVLTSSIVAIAYLCVLPLILQTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDITTVSICKKCINPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIEKMKQLDKNKLQAVANQTYHQTPPPTFSFRERVTHKSLVYLWFLCSSVALALGALTVWHAVLISRGETSIERHINKKERRRLQAKGRVFRNHYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWDPPPWVTAHSASVMAV", "length": 377, "header": "tr|A0A4X1U9U9-1|A0A4X1U9U9_PIG Isoform 1 of Palmitoyltransferase OS=Sus scrofa OX=9823 GN=ZDHHC16 PE=3 SV=1 CANONICAL=A0A4X1U9U9-1" }, "locus": { "chromosome": "14", "start_pos": 108852318, "end_pos": 108846932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056855.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056855.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041808.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041808.1" } ] } }, { "isoform_ac": "A0A4X1UCV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9/entry#A0A4X1UCV1-1", "sequence": { "sequence": "MRGQRSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPIYWLVDNVIRWCGVVFVVLVIVLTSSIVAIAYLCVLPLILQTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDITTVSICKKCINPKPARTHHCSICNSYGSWDLFREAYAAIEKMKQLDKNKLQAVANQTYHQTPPPTFSFRERVTHKSLVYLWFLCSSVALALGALTVWHAVLISRGETSIERHINKKERRRLQAKGRVFRNHYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWDPPPWVTAHSASVMAV", "length": 338, "header": "tr|A0A4X1UCV1-1|A0A4X1UCV1_PIG Computationally mapped isoform of Zinc finger DHHC-type palmitoyltransferase 16 OS=Sus scrofa OX=9823 GN=ZDHHC16 PE=4 SV=1 CANONICAL=A0A4X1U9U9-1" }, "locus": { "chromosome": "14", "start_pos": 108852318, "end_pos": 108846932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058210.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058210.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052816.1", "url": "https://www.ensembl.org/id/ENSSSCP00000052816.1" } ] } }, { "isoform_ac": "A0A8D1EJ15-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9/entry#A0A8D1EJ15-1", "sequence": { "sequence": "MRGQRSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPIYWLVDNVIRWCGVGRNDITTVSICKKCINPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIETYHQTPPPTFSFRERVTHKSLVYLWFLCSSVALALGALTVWHAVLISRGETSIERHINKKERRRLQAKGRVFRNHYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWDPPPWVTAHSASVMAV", "length": 296, "header": "tr|A0A8D1EJ15-1|A0A4X1U9U9_PIG Computationally mapped isoform of Palmitoyltransferase OS=Sus scrofa OX=9823 GN=ZDHHC16 PE=3 SV=1 CANONICAL=A0A4X1U9U9-1" }, "locus": { "chromosome": "14", "start_pos": 108852318, "end_pos": 108846932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049902.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049902.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042377.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042377.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1EJ15", "url": "https://www.uniprot.org/uniprotkb/A0A8D1EJ15" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152371", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IF99-1", "protein_name": "Palmitoyltransferase ZDHHC16B", "gene_name": "zdhhc16b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRSWRWSVSRIMRLFLRWFRLCPRRGHRKRSRVRDLWNYGMVVLKSLYYNVQTNSDTVLDCMFEPIYWLVDNMTRWFGVVFVCLVMALTSSVVVIVYLCVLPIIFSSYPVYWILWHLCYGHWNLLMVVFHYYKATTTQPGFPPQEKTDIPTVTICKKCIVPKPARTHHCSICNRCILKMDHHCPWLNNCVGHFNHRYFFSFCLFMTMGCVYCSISAKDMFLDAYNAIESGRYKGGASQGEAVPGAGLIYISFQHQSSYQTPPPAFTHQERMVHKSLVYLWVLTSSVAVALGALTLWHAILITRGETSVERHINRKERRRLKLRGKLFRNPYHHGRINNWRIFFGVEKGSDWLWRVLLPSTHPPLGDGLTWDCPAYKSSTTAI", "length": 382 }, "evidence": [ { "id": "A0A4X1U9U9", "url": "https://omabrowser.org/oma/group/A0A4X1U9U9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q58CU4-1", "protein_name": "Palmitoyltransferase ZDHHC16", "gene_name": "ZDHHC16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGQWSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPIYWLVDNVIRWCGVVFVVLVIVLTSSIVAIAYLCVLPLILQTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDMTTVSICKKCINPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIEKMKQLDKNKLQAVANQTYHQTPPPTFSFRERVTHKSLVYLWFLCSSVALALGALTIWHAVLISRGETSIERHINKKERQRLQAKGRVFRNHYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWDPPPWVTAHSASVMAV", "length": 377 }, "evidence": [ { "id": "A0A4X1U9U9", "url": "https://omabrowser.org/oma/group/A0A4X1U9U9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q969W1-1", "protein_name": "Palmitoyltransferase ZDHHC16", "gene_name": "ZDHHC16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGQRSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPVYWLVDNVIRWFGVVFVVLVIVLTGSIVAIAYLCVLPLILRTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDIATVSICKKCIYPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIEKMKQLDKNKLQAVANQTYHQTPPPTFSFRERMTHKSLVYLWFLCSSVALALGALTVWHAVLISRGETSIERHINKKERRRLQAKGRVFRNPYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWEPPPWVTAHSASVMAV", "length": 377 }, "evidence": [ { "id": "A0A4X1U9U9", "url": "https://omabrowser.org/oma/group/A0A4X1U9U9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ESG8-1", "protein_name": "Palmitoyltransferase ZDHHC16", "gene_name": "Zdhhc16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGQRSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPVYWLVDNVIRWFGVVFVVLVIVLTGSIVAIAYLCVLPLILRTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDIATVSICKKCIYPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIETYHQTPPPTFSFRERITHKSLVYLWFLCSSVALALGALTMWHAVLISRGETSIERHINKKERRRLQAKGRVFRNPYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWDPPPWVTAHSASVMAV", "length": 361 }, "evidence": [ { "id": "A0A4X1U9U9", "url": "https://omabrowser.org/oma/group/A0A4X1U9U9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9U9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9U9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9U9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9" } ], "pmid": "" }, { "name": "palmitoyltransferase activity", "id": "GO:0016409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016409", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9U9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9U9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9U9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U9U9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U9" }, { "id": "PF01529", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Palmitoyltransferase DHHC", "eco_id": "ECO_0000259", "start_pos": 155, "end_pos": 302, "start_aa": "Ser", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 245, "end_pos": 247 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TW46-1", "uniprot_ac": "A0A4X1TW46", "uniprot_id": "A0A4X1TW46_PIG", "mass": { "chemical_mass": 44229.0, "monoisotopic_mass": 44229.0 }, "refseq": { "ac": "XP_005672701", "name": "VPS37A subunit of ESCRT-I isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005672701" }, "gene_names": [ { "name": "VPS37A", "type": "recommended", "evidence": [ { "id": "A0A4X1TW46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46" } ] }, { "name": "VPS37A", "type": "synonym", "evidence": [ { "id": "XP_005672701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005672701" } ] } ], "protein_names": [ { "name": "Vacuolar protein sorting-associated protein 37A", "type": "recommended", "evidence": [ { "id": "A0A4X1TW46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46/entry#names_and_taxonomy" } ] }, { "name": "ESCRT-I complex subunit VPS37A", "type": "synonym", "evidence": [ { "id": "A0A4X1TW46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46/entry#names_and_taxonomy" } ] }, { "name": "VPS37A subunit of ESCRT-I isoform 1", "type": "synonym", "evidence": [ { "id": "XP_005672701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005672701" } ] }, { "name": "VPS37A, ESCRT-I subunit", "type": "synonym", "evidence": [ { "id": "XP_005672701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005672701" } ] }, { "name": "Vacuolar protein sorting-associated protein 37A", "type": "synonym", "evidence": [ { "id": "XP_005672701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005672701" } ] }, { "name": "vacuolar protein sorting 37 homolog A", "type": "synonym", "evidence": [ { "id": "XP_005672701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005672701" } ] } ], "function": [ { "annotation": "Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BBD9", "url": "https://www.uniprot.org/uniprotkb/A0A287BBD9#function" }, { "database": "UniProtKB", "id": "ARBA00025010", "url": "https://www.uniprot.org/uniprotkb/ARBA00025010#function" }, { "database": "UniProtKB", "id": "A0A480VRF7", "url": "https://www.uniprot.org/uniprotkb/A0A480VRF7#function" }, { "database": "UniProtKB", "id": "A0A4X1TW46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46#function" }, { "database": "UniProtKB", "id": "A0A4X1TW60", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW60#function" }, { "database": "UniProtKB", "id": "A0A4X1TW77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW77#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "VPS37A", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46", "locus": { "chromosome": "17", "start_pos": 4988074, "end_pos": 4949644, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006984", "url": "https://www.ensembl.org/id/ENSSSCG00000006984" } ] } } ], "crossref": [ { "id": "A0A4X1TW46", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TW46", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006984", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006984", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11685", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11685", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513122", "url": "https://www.ncbi.nlm.nih.gov/gene/100513122", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513122", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513122", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HPWCNEH", "url": "https://omabrowser.org/oma/group/HPWCNEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13678:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13678:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-917729", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917729", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005672701", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005672701", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BBD9", "url": "https://www.uniprot.org/uniprotkb/A0A287BBD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BBD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BBD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480VRF7", "url": "https://www.uniprot.org/uniprotkb/A0A480VRF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480VRF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A480VRF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TW46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TW46-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TW60", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TW60-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TW77", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TW77-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWLFPLTKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTVNNLTININILLPPQFPQEKPVISVYPPVRHHLVDKQGVYVTSPLINNFTMHSDLGKIIQSLLDEFWKNPPVLAPASTAFPYLYGNPSGMPPYASQGFPFLPPYPPQEANRTISSLSVADTVSSSTTSYTTAKPAAPSFGVLSNLPLPVPTTDTSAPISQNGSGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKNIEELARKNLLLEPSLEAKRQSVLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKTDIDDFLSSFMEKRTIYHCRRAKEEKLQQVIAMHSQFHAPL", "length": 397, "header": "tr|A0A4X1TW46-1|A0A4X1TW46_PIG Isoform 1 of Vacuolar protein sorting-associated protein 37A OS=Sus scrofa OX=9823 GN=VPS37A PE=1 SV=1 CANONICAL=A0A4X1TW46-1" }, "isoforms": [ { "isoform_ac": "A0A287BBD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46/entry#A0A287BBD9-1", "sequence": { "sequence": "MSWLFPLTKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTVNNLTININILLPPQFPQEKPVISVYPPVRHHLVDKQGVYVTSPLINNFTMHSDLGKIIQSLLDEFWKNPPVLAPASTAFPYLYGNPSGMPPYASQGFPFLPPYPPQEANRTISSLSVADTVSSSTTSYTTAKPAAPSFGVLSNLPLPVPTTDTSAPISQNGSGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKNIEELAYNEIASPYLYLYPIFFPSNDCSASALQARLKVAAHEAEEESDNIAEDFLEGKTDIDDFLSSFMEKRTIYHCRRAKEEKLQQVIAMHSQFHAPL", "length": 373, "header": "tr|A0A287BBD9-1|A0A4X1TW46_PIG Computationally mapped isoform of Vacuolar protein sorting-associated protein 37A OS=Sus scrofa OX=9823 GN=VPS37A PE=1 SV=2 CANONICAL=A0A4X1TW46-1" }, "locus": { "chromosome": "17", "start_pos": 4985845, "end_pos": 4949949, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050932.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050932.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053838.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053838.2" } ] } }, { "isoform_ac": "A0A480VRF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46/entry#A0A480VRF7-1", "sequence": { "sequence": "MSWLFPLTKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTVNNLTININILLPPQFPQEKPVISVYPPVRHHLVDKQGVYVTSPLINNFTMHSDLGKIIQSLLDEFWKNPPVLAPASTAFPYLYGNPSGMPPYASQGFPFLPPYPPQEANRTISSLSVADTVSSSTTSYTTAKPAAPSFGVLSNLPLPVPTTDTSAPISQNGSGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKNIEELARKNLLLEPSLEAKRQSVLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKTDIDDFLSSFMEKRTVCNTLRLRTSDSIIANYLHIFMSKRTLAHY", "length": 401, "header": "tr|A0A480VRF7-1|A0A4X1TW46_PIG Computationally mapped isoform of Vacuolar protein sorting-associated protein 37A OS=Sus scrofa OX=9823 GN=VPS37A PE=1 SV=1 CANONICAL=A0A4X1TW46-1" }, "locus": { "chromosome": "17", "start_pos": 4984819, "end_pos": 4949949, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057561.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057561.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031736.2", "url": "https://www.ensembl.org/id/ENSSSCP00000031736.2" } ] } }, { "isoform_ac": "A0A4X1TW46-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46/entry#A0A4X1TW46-1", "sequence": { "sequence": "MSWLFPLTKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTVNNLTININILLPPQFPQEKPVISVYPPVRHHLVDKQGVYVTSPLINNFTMHSDLGKIIQSLLDEFWKNPPVLAPASTAFPYLYGNPSGMPPYASQGFPFLPPYPPQEANRTISSLSVADTVSSSTTSYTTAKPAAPSFGVLSNLPLPVPTTDTSAPISQNGSGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKNIEELARKNLLLEPSLEAKRQSVLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKTDIDDFLSSFMEKRTIYHCRRAKEEKLQQVIAMHSQFHAPL", "length": 397, "header": "tr|A0A4X1TW46-1|A0A4X1TW46_PIG Isoform 1 of Vacuolar protein sorting-associated protein 37A OS=Sus scrofa OX=9823 GN=VPS37A PE=1 SV=1 CANONICAL=A0A4X1TW46-1" }, "locus": { "chromosome": "17", "start_pos": 4985845, "end_pos": 4949949, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054191.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054191.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059049.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059049.2" } ] } }, { "isoform_ac": "A0A4X1TW60-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46/entry#A0A4X1TW60-1", "sequence": { "sequence": "MSWLFPLTKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTVNNLTININILLPPQFPQEKPVISVYPPVRHHLVDKQGVYVTSPLINNFTMHSDLGKIIQSLLDEFWKNPPVLAPASTAFPYLYGNPSGMPPYASQGFPFLPPYPPQEANRTISSLSVADTVSSSTTSYTTAKPAAPSFGVLSNLPLPVPTTDTSAPISQNGSGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKNIEELARKNLLLEPSLEAKRQSVLDKSCSASALQARLKVAAHEAEEESDNIAEDFLEGKTDIDDFLSSFMEKRTIYHCRRAKEEKLQQVIAMHSQFHAPL", "length": 374, "header": "tr|A0A4X1TW60-1|A0A4X1TW60_PIG Computationally mapped isoform of VPS37A subunit of ESCRT-I OS=Sus scrofa OX=9823 GN=VPS37A PE=1 SV=1 CANONICAL=A0A4X1TW46-1" }, "locus": { "chromosome": "17", "start_pos": 4985845, "end_pos": 4949949, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051067.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051067.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032702.1", "url": "https://www.ensembl.org/id/ENSSSCP00000032702.1" } ] } }, { "isoform_ac": "A0A4X1TW77-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46/entry#A0A4X1TW77-1", "sequence": { "sequence": "MSWLFPLTKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSRLLPPQFPQEKPVISVYPPVRHHLVDKQGVYVTSPLINNFTMHSDLGKIIQSLLDEFWKNPPVLAPASTAFPYLYGNPSGMPPYASQGFPFLPPYPPQEANRTISSLSVADTVSSSTTSYTTAKPAAPSFGVLSNLPLPVPTTDTSAPISQNGSGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKNIEELARKNLLLEPSLEAKRQSVLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKTDIDDFLSSFMEKRTIYHCRRAKEEKLQQVIAMHSQFHAPL", "length": 372, "header": "tr|A0A4X1TW77-1|A0A4X1TW77_PIG Computationally mapped isoform of VPS37A subunit of ESCRT-I OS=Sus scrofa OX=9823 GN=VPS37A PE=1 SV=1 CANONICAL=A0A4X1TW46-1" }, "locus": { "chromosome": "17", "start_pos": 4985845, "end_pos": 4949949, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007649.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007649.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007442.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007442.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BBD9", "url": "https://www.uniprot.org/uniprotkb/A0A287BBD9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513122", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513122", "resource": "KEGG Pathway" }, { "id": "R-SSC-917729", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917729", "resource": "Reactome", "description": "Endosomal Sorting Complex Required For Transport (ESCRT)" } ], "orthologs": [ { "uniprot_canonical_ac": "Q55DV8-1", "protein_name": "Vacuolar protein sorting-associated protein 37", "gene_name": "vps37", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKPDLNSLSIKMKQINLLKERFSHTIEVVKDSTFKIPFLNVHLLISLPVNFPNSPPAYFLEILQTHQPVSLPPNYQWTQISNLASVTVHIMEPFIKDSRILETLIEQVKRSQAMQQQQQQQQQQQRNQQAQQQYSPPPPYKDQPINKQPAQQQPQPVQQKPQQQQNGTNKIPMIPTEFPELKSKSVEELEELLKNEDSLNAFIYSYDEVSELSNRKSKLLSENERLTKITDPLPNDINDLSANLMTSKQKLEELKRKQEQLQQKKNSIADKYSQQNLLEILNDSISDLESESDNIVHSFLEGNLELKEFKKQFKEKRSSYHSKCANKDLFFK", "length": 333 }, "evidence": [ { "id": "A0A4X1TW46", "url": "https://omabrowser.org/oma/group/A0A4X1TW46/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8CHS8-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "Vps37a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSWLFPLAKSASSSAAGSPAGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTVNNLTININILLPPQFPQEKPVISVYPPIRHHLMDSQGLYVTSPLVSNFTMHSDLGKIIQSLLDEFWKNPPVLAPTSTTFPYLYSNPGGMPPYPSQGFPFLPPYPPPEANRNITSLSVADTVSSSTTSYTAAKPVAPSFGILSSLPLPVPTTESSASVNQNGFGYKMPDIPDAFPELSELSVSQLTDMNEQEEVLLEQFLMLPQLKQIITDKEDLVKNIEELARKNLLLEHSLEGKRQTVLDKYELLLQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKTEIDDFLNSFKEKRTICHCRRAKEEKLHQVIAMHSQFHAPL", "length": 397 }, "evidence": [ { "id": "A0A4X1TW46", "url": "https://omabrowser.org/oma/group/A0A4X1TW46/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSWLFPLTKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTINNLTININILLPPQFPQEKPVISVYPPIRHHLMDKQGVYVTSPLVNNFTMHSDLGKIIQSLLDEFWKNPPVLAPTSTAFPYLYSNPSGMSPYASQGFPFLPPYPPQEANRSITSLSVADTVSSSTTSHTTAKPAAPSFGVLSNLPLPIPTVDASIPTSQNGFGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQTVLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKMEIDDFLSSFMEKRTICHCRRAKEEKLQQAIAMHSQFHAPL", "length": 397 }, "evidence": [ { "id": "A0A4X1TW46", "url": "https://omabrowser.org/oma/group/A0A4X1TW46/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46" } ], "pmid": "" }, { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46" } ], "pmid": "" }, { "name": "ESCRT I complex", "id": "GO:0000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000813", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TW46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW46" }, { "id": "PS51314", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51314" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VPS37 C-terminal", "eco_id": "ECO_0000259", "start_pos": 308, "end_pos": 397, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 218, "end_pos": 220 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UX87-1", "uniprot_ac": "A0A4X1UX87", "uniprot_id": "A0A4X1UX87_PIG", "mass": { "chemical_mass": 18929.0, "monoisotopic_mass": 18929.0 }, "refseq": { "ac": "XP_005673510", "name": "AP-1 complex subunit sigma-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005673510" }, "gene_names": [ { "name": "AP1S2", "type": "recommended", "evidence": [ { "id": "A0A4X1UX87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87" } ] }, { "name": "AP1S2", "type": "synonym", "evidence": [ { "id": "XP_005673510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005673510" } ] } ], "protein_names": [ { "name": "AP complex subunit sigma", "type": "recommended", "evidence": [ { "id": "A0A4X1UX87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87/entry#names_and_taxonomy" } ] }, { "name": "AP-1 complex subunit sigma-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005673510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005673510" } ] } ], "function": [ { "annotation": "Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BBP6", "url": "https://www.uniprot.org/uniprotkb/A0A287BBP6#function" }, { "database": "UniProtKB", "id": "ARBA00059060", "url": "https://www.uniprot.org/uniprotkb/ARBA00059060#function" }, { "database": "UniProtKB", "id": "A0A4X1UX87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87#function" }, { "database": "UniProtKB", "id": "A0A4X1UYB3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UYB3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UX87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AP1S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87", "locus": { "chromosome": "X", "start_pos": 12367795, "end_pos": 12397677, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036074", "url": "https://www.ensembl.org/id/ENSSSCG00000036074" } ] } } ], "crossref": [ { "id": "A0A4X1UX87", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UX87", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000036074", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036074", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14831", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14831", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100517795", "url": "https://www.ncbi.nlm.nih.gov/gene/100517795", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517795", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517795", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UX87", "url": "https://www.orthodb.org/?gene=A0A4X1UX87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UYB3", "url": "https://www.orthodb.org/?gene=A0A4X1UYB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005673510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005673510", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BBP6", "url": "https://www.uniprot.org/uniprotkb/A0A287BBP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BBP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BBP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UX87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UX87-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UYB3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UYB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UYB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UYB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEDAKEAETPRSVLEEIGLT", "length": 160, "header": "tr|A0A4X1UX87-1|A0A4X1UX87_PIG Isoform 1 of AP complex subunit sigma OS=Sus scrofa OX=9823 GN=AP1S2 PE=1 SV=1 CANONICAL=A0A4X1UX87-1" }, "isoforms": [ { "isoform_ac": "A0A287BBP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87/entry#A0A287BBP6-1", "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEVSYSRFS", "length": 149, "header": "tr|A0A287BBP6-1|A0A4X1UX87_PIG Computationally mapped isoform of AP complex subunit sigma OS=Sus scrofa OX=9823 GN=AP1S2 PE=1 SV=3 CANONICAL=A0A4X1UX87-1" }, "locus": { "chromosome": "X", "start_pos": 12395404, "end_pos": 12387315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065448.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065448.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053766.3", "url": "https://www.ensembl.org/id/ENSSSCP00000053766.3" } ] } }, { "isoform_ac": "A0A4X1UX87-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87/entry#A0A4X1UX87-1", "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEDAKEAETPRSVLEEIGLT", "length": 160, "header": "tr|A0A4X1UX87-1|A0A4X1UX87_PIG Isoform 1 of AP complex subunit sigma OS=Sus scrofa OX=9823 GN=AP1S2 PE=1 SV=1 CANONICAL=A0A4X1UX87-1" }, "locus": { "chromosome": "X", "start_pos": 12395404, "end_pos": 12369289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068080.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068080.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070550.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070550.1" } ] } }, { "isoform_ac": "A0A4X1UYB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87/entry#A0A4X1UYB3-1", "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT", "length": 157, "header": "tr|A0A4X1UYB3-1|A0A4X1UYB3_PIG Computationally mapped isoform of AP complex subunit sigma OS=Sus scrofa OX=9823 GN=AP1S2 PE=3 SV=1 CANONICAL=A0A4X1UX87-1" }, "locus": { "chromosome": "X", "start_pos": 12395404, "end_pos": 12369289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081951.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081951.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072693.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072693.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BBP6", "url": "https://www.uniprot.org/uniprotkb/A0A287BBP6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517795", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517795", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UX87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UX87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UX87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UX87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UX87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UX87" }, { "id": "PF01217", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP complex mu/sigma subunit", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 140, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VNN9-1", "uniprot_ac": "A0A4X1VNN9", "uniprot_id": "A0A4X1VNN9_PIG", "mass": { "chemical_mass": 22591.0, "monoisotopic_mass": 22591.0 }, "refseq": { "ac": "XP_020950537", "name": "small ribosomal subunit protein uS4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950537" }, "gene_names": [ { "name": "RPS9", "type": "recommended", "evidence": [ { "id": "A0A4X1VNN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" } ] }, { "name": "RPS9", "type": "synonym", "evidence": [ { "id": "XP_020950537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950537" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein uS4", "type": "recommended", "evidence": [ { "id": "A0A4X1VNN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S9", "type": "synonym", "evidence": [ { "id": "XP_020950537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950537" }, { "id": "A0A4X1VNN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9/entry#names_and_taxonomy" } ] }, { "name": "small ribosomal subunit protein uS4", "type": "synonym", "evidence": [ { "id": "XP_020950537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950537" } ] } ], "function": [ { "annotation": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F8D2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8D2#function" }, { "database": "UniProtKB", "id": "ARBA00045441", "url": "https://www.uniprot.org/uniprotkb/ARBA00045441#function" }, { "database": "UniProtKB", "id": "A0A8W4FD01", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FD01#function" }, { "database": "UniProtKB", "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9#function" }, { "database": "UniProtKB", "id": "A0A480LDU1", "url": "https://www.uniprot.org/uniprotkb/A0A480LDU1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPS9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9", "locus": { "chromosome": "6", "start_pos": 55920934, "end_pos": 55927280, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000029785", "url": "https://www.ensembl.org/id/ENSSSCG00000029785" } ] } } ], "crossref": [ { "id": "A0A4X1VNN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1VNN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000029785", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000029785", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00165", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00165", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100622613", "url": "https://www.ncbi.nlm.nih.gov/gene/100622613", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100622613", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622613", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RQFITHG", "url": "https://omabrowser.org/oma/group/RQFITHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1VNN9", "url": "https://www.orthodb.org/?gene=A0A4X1VNN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11831", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11831", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11831:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11831:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00163", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00163", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01479", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01479", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020950537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950537", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A480LDU1", "url": "https://www.uniprot.org/uniprotkb/A0A480LDU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480LDU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A480LDU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VNN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8D2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8D2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FD01", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FD01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FD01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FD01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194, "header": "tr|A0A4X1VNN9-1|A0A4X1VNN9_PIG Isoform 1 of Small ribosomal subunit protein uS4 OS=Sus scrofa OX=9823 GN=RPS9 PE=1 SV=1 CANONICAL=A0A4X1VNN9-1" }, "isoforms": [ { "isoform_ac": "A0A480LDU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9/entry#A0A480LDU1-1", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHISPRR", "length": 139, "header": "tr|A0A480LDU1-1|A0A4X1VNN9_PIG Computationally mapped isoform of Small ribosomal subunit protein uS4 OS=Sus scrofa OX=9823 GN=RPS9 PE=1 SV=1 CANONICAL=A0A4X1VNN9-1" }, "locus": { "chromosome": "6", "start_pos": 55926905, "end_pos": 55922304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053934.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053934.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058496.3", "url": "https://www.ensembl.org/id/ENSSSCP00000058496.3" } ] } }, { "isoform_ac": "A0A4X1VNN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9/entry#A0A4X1VNN9-1", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194, "header": "tr|A0A4X1VNN9-1|A0A4X1VNN9_PIG Isoform 1 of Small ribosomal subunit protein uS4 OS=Sus scrofa OX=9823 GN=RPS9 PE=1 SV=1 CANONICAL=A0A4X1VNN9-1" }, "locus": { "chromosome": "6", "start_pos": 55926905, "end_pos": 55920999, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027911.3", "url": "https://www.ensembl.org/id/ENSSSCT00000027911.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022609.3", "url": "https://www.ensembl.org/id/ENSSSCP00000022609.3" } ] } }, { "isoform_ac": "A0A8W4F8D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9/entry#A0A8W4F8D2-1", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRYHLWSRPPRPSPSDGCPR", "length": 154, "header": "tr|A0A8W4F8D2-1|A0A4X1VNN9_PIG Computationally mapped isoform of Small ribosomal subunit protein uS4 OS=Sus scrofa OX=9823 GN=RPS9 PE=1 SV=1 CANONICAL=A0A4X1VNN9-1" }, "locus": { "chromosome": "6", "start_pos": 55926905, "end_pos": 55922343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094603.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094603.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075525.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075525.1" } ] } }, { "isoform_ac": "A0A8W4FD01-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9/entry#A0A8W4FD01-1", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGSASRW", "length": 79, "header": "tr|A0A8W4FD01-1|A0A4X1VNN9_PIG Computationally mapped isoform of Small ribosomal subunit protein uS4 OS=Sus scrofa OX=9823 GN=RPS9 PE=1 SV=1 CANONICAL=A0A4X1VNN9-1" }, "locus": { "chromosome": "6", "start_pos": 55926905, "end_pos": 55921157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100331.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100331.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077144.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077144.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 15, "start_aa": "Thr", "end_pos": 15, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr15", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F8D2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8D2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100622613", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622613", "resource": "KEGG Pathway" }, { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-SSC-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-SSC-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "A6QLG5-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "RPS9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A4X1VNN9", "url": "https://omabrowser.org/oma/group/A0A4X1VNN9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O13516-1", "protein_name": "Small ribosomal subunit protein uS4A", "gene_name": "RPS9A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKKEIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGEAADEADEADEE", "length": 197 }, "evidence": [ { "id": "A0A4X1VNN9", "url": "https://omabrowser.org/oma/group/A0A4X1VNN9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P14132-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "rps9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNYSKTSHTPRRPFEKERIDAELKVVGEFGLKNKNEVWRVQYALAKIRKAARELLVLDEKDPKRIFEGSALLRRLHKLGVMEESKNKLDYILNLKVQDFMERRLQTLVFKNGLAKSIHHARVLIKGRHIRVGKQLVNVPSFLVRVESQKHLGLASTSPLAGGRPGRRARKMAKNNSSKGEEEN", "length": 185 }, "evidence": [ { "id": "A0A4X1VNN9", "url": "https://omabrowser.org/oma/group/A0A4X1VNN9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A4X1VNN9", "url": "https://omabrowser.org/oma/group/A0A4X1VNN9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P46781-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "RPS9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A4X1VNN9", "url": "https://omabrowser.org/oma/group/A0A4X1VNN9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P55935-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "RpS9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVNGRIPSVFSKTYVTPRRPYEKARLDQELKIIGEYGLRNKREVWRVKYALAKIRKAARELLTLDEKDEKRLFQGNALLRRLVRIGVLDESRMKLDYVLGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFVVRLDSQKHIDFSLKSPFGGGRPGRVKRKNLKKNQGGGGGAAEEEED", "length": 195 }, "evidence": [ { "id": "A0A4X1VNN9", "url": "https://omabrowser.org/oma/group/A0A4X1VNN9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q6ZWN5-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A4X1VNN9", "url": "https://omabrowser.org/oma/group/A0A4X1VNN9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" } ], "pmid": "" }, { "name": "small ribosomal subunit", "id": "GO:0015935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015935", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VNN9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1VNN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" }, { "id": "SM00363", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00363" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNA-binding S4", "eco_id": "ECO_0000259", "start_pos": 108, "end_pos": 179, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1VNN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VNN9" }, { "id": "SM01390", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01390" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small ribosomal subunit protein uS4 N-terminal", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 107, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 15 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1USF8-1", "uniprot_ac": "A0A4X1USF8", "uniprot_id": "A0A4X1USF8_PIG", "mass": { "chemical_mass": 51781.0, "monoisotopic_mass": 51781.0 }, "refseq": { "ac": "XP_003121641", "name": "regulator of microtubule dynamics protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121641" }, "gene_names": [ { "name": "RMDN3", "type": "recommended", "evidence": [ { "id": "A0A4X1USF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ] }, { "name": "RMDN3", "type": "synonym", "evidence": [ { "id": "XP_003121641", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121641" } ] } ], "protein_names": [ { "name": "Regulator of microtubule dynamics protein 3", "type": "recommended", "evidence": [ { "id": "A0A4X1USF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8/entry#names_and_taxonomy" } ] }, { "name": "Protein FAM82A2", "type": "synonym", "evidence": [ { "id": "A0A4X1USF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8/entry#names_and_taxonomy" } ] }, { "name": "Protein FAM82C", "type": "synonym", "evidence": [ { "id": "A0A4X1USF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8/entry#names_and_taxonomy" } ] }, { "name": "regulator of microtubule dynamics protein 3", "type": "synonym", "evidence": [ { "id": "XP_003121641", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121641" } ] } ], "function": [ { "annotation": "Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A481CB65", "url": "https://www.uniprot.org/uniprotkb/A0A481CB65#function" }, { "database": "UniProtKB", "id": "ARBA00045208", "url": "https://www.uniprot.org/uniprotkb/ARBA00045208#function" }, { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8#function" }, { "database": "UniProtKB", "id": "A0A5G2QYV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYV7#function" }, { "database": "UniProtKB", "id": "F1SSS8", "url": "https://www.uniprot.org/uniprotkb/F1SSS8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RMDN3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8", "locus": { "chromosome": "1", "start_pos": 130615722, "end_pos": 130574237, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004765", "url": "https://www.ensembl.org/id/ENSSSCG00000004765" } ] } } ], "crossref": [ { "id": "A0A4X1USF8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1USF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004765", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004765", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100519696", "url": "https://www.ncbi.nlm.nih.gov/gene/100519696", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519696", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519696", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QHESMHS", "url": "https://omabrowser.org/oma/group/QHESMHS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1USF8", "url": "https://www.orthodb.org/?gene=A0A4X1USF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16056:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16056:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003121641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121641", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A481CB65", "url": "https://www.uniprot.org/uniprotkb/A0A481CB65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A481CB65-1", "url": "https://www.uniprot.org/uniprotkb/A0A481CB65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1USF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SSS8", "url": "https://www.uniprot.org/uniprotkb/F1SSS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SSS8-1", "url": "https://www.uniprot.org/uniprotkb/F1SSS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSLGALGGARAGLGLLLGTAAGLGFLCALYSQRWKRTRRHGQSQSNSLDYTQTSEPGRHVRPLRAVPGEAGDAAVLSTLPRAGQEEVLDRLEFVLTSLVALRREVEELRSSLQGLAGQIVGEVRSHIEENQKVARRRRFLFSRERSDSTGSSSVYFTATSGTTFTDAESEGGYTTANAESDYERDSERESDDDGEDEVSCETVKMGRRDSLDLEVEVALGPAPGALEAGGSPGLEHVLPLLQQADELHQGDEQGKREGFQLLLKNKLVHGSRQDFLWRLARAYSDMCELAEEASEKKSHALSGKEAAEAALEKGDENAESHQWYAVLCGQLAEHESIQKRIQSGFSFKEHVDKAIALQPENPMTHFLLGRWCYQVSHLSWLEKKTATALSESPLSATVQDALQSFLKAEELKPGFSKAGRIYISKCYRELGKNPEAKQWVKLALELPDVTKEDSAFQKDLEELEVILGE", "length": 470, "header": "tr|A0A4X1USF8-1|A0A4X1USF8_PIG Isoform 1 of Regulator of microtubule dynamics protein 3 OS=Sus scrofa OX=9823 GN=RMDN3 PE=1 SV=1 CANONICAL=A0A4X1USF8-1" }, "isoforms": [ { "isoform_ac": "A0A481CB65-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8/entry#A0A481CB65-1", "sequence": { "sequence": "MSSLGALGGARAGLGLLLGTAAGLGFLCALYSQRWKRTRRHGQSQSNSLDYTQTSEPGRHVRPLRAVPGEAGDAAVLSTLPRAGQEEVLDRLEFVLTSLVALRREVEELRSSLQGLAGQIVGEVRSHIEENQKVARRRRFLFSRERSDSTGSSSVYFTATSGTTFTDAESEGGYTTANAESDYERDSERESDDDGEDEVSCETVKMGRRDSLDLEVEVALGPAPGALEAGGSPGLEHVLPLLQQADELHQGDEQGKREGFQLLLKNKLVHGSRQDFLWRLARAYSDMCELAEEASEKKSHALSGKEAAEAALEKGDENAESHQWYAVLCGQLAEHESIQKRIQSGFSFKEHVDKAIALQPENPMTHFLLGRWCYQVSHLSWLEKKTATALSESPLSATVQDALQSFLKAEELKPGFSKAGRIYISKCYRELGKNPEAKQWVKLALELPDVTKEVINTSELF", "length": 461, "header": "tr|A0A481CB65-1|A0A4X1USF8_PIG Computationally mapped isoform of Regulator of microtubule dynamics protein 3 OS=Sus scrofa OX=9823 GN=RMDN3 PE=1 SV=1 CANONICAL=A0A4X1USF8-1" }, "locus": { "chromosome": "1", "start_pos": 130590546, "end_pos": 130574802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092069.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092069.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074592.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074592.1" } ] } }, { "isoform_ac": "A0A4X1USF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8/entry#A0A4X1USF8-1", "sequence": { "sequence": "MSSLGALGGARAGLGLLLGTAAGLGFLCALYSQRWKRTRRHGQSQSNSLDYTQTSEPGRHVRPLRAVPGEAGDAAVLSTLPRAGQEEVLDRLEFVLTSLVALRREVEELRSSLQGLAGQIVGEVRSHIEENQKVARRRRFLFSRERSDSTGSSSVYFTATSGTTFTDAESEGGYTTANAESDYERDSERESDDDGEDEVSCETVKMGRRDSLDLEVEVALGPAPGALEAGGSPGLEHVLPLLQQADELHQGDEQGKREGFQLLLKNKLVHGSRQDFLWRLARAYSDMCELAEEASEKKSHALSGKEAAEAALEKGDENAESHQWYAVLCGQLAEHESIQKRIQSGFSFKEHVDKAIALQPENPMTHFLLGRWCYQVSHLSWLEKKTATALSESPLSATVQDALQSFLKAEELKPGFSKAGRIYISKCYRELGKNPEAKQWVKLALELPDVTKEDSAFQKDLEELEVILGE", "length": 470, "header": "tr|A0A4X1USF8-1|A0A4X1USF8_PIG Isoform 1 of Regulator of microtubule dynamics protein 3 OS=Sus scrofa OX=9823 GN=RMDN3 PE=1 SV=1 CANONICAL=A0A4X1USF8-1" }, "locus": { "chromosome": "1", "start_pos": 130590880, "end_pos": 130574802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065283.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065283.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053649.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053649.1" } ] } }, { "isoform_ac": "A0A5G2QYV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8/entry#A0A5G2QYV7-1", "sequence": { "sequence": "MSSLGALGGARAGLGLLLGTAAGLGFLCALYSQRWKRTRRHGQSQSNSLDYTQTSEPGRHVRPLRAVPGEAGDAAVLSTLPRAGQEEVLDRLEFVLTSLVALRREVEELRSSLQGLAGQIVGEVRSHIEENQKVARRRRFLFSRERSDSTGSSSVYFTATSGTTFTDAESEGGYTTANAESDYERDSERESDDDGEDEVSCETVKMGRRDSLDLEVEVALGPAPGALEAGGSPGLEHVLPLLQQADELHQGDEQGKREGFQLLLKNKLVHGSRQDFLWRLARAYSDMCELAEEASEKKSHALSGKEAAEAALEKGDENAESHQWYAVLCGQLAEHESIQKRIQSGFSFKEHVDKAIALQPENPMTHFLLGRWCYQVSHLSWLEKKTATALSESPLSATVQDALQSFLKAEELKPGFSKAGRIYISKCYRELGKNPEAKQWVKLALELPDVTKEGRTQSTRKFPS", "length": 464, "header": "tr|A0A5G2QYV7-1|A0A4X1USF8_PIG Computationally mapped isoform of Regulator of microtubule dynamics protein 3 OS=Sus scrofa OX=9823 GN=RMDN3 PE=1 SV=1 CANONICAL=A0A4X1USF8-1" }, "locus": { "chromosome": "1", "start_pos": 130614873, "end_pos": 130574802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073182.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073182.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070091.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070091.1" } ] } }, { "isoform_ac": "F1SSS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8/entry#F1SSS8-1", "sequence": { "sequence": "MSSLGALGGARAGLGLLLGTAAGLGFLCALYSQRWKRTRRHGQSQSNSLDYTQTSEPGRHVRPLRAVPGEAGDAAVLSTLPRAGQEEVLDRLEFVLTSLVALRREVEELRSSLQGLAGQIVGEVRSHIEENQKVARRRRFLFSRERSDSTGSSSVYFTATSGTTFTDAESEGGYTTANAESDYERDSERESDDDGEDEVSCETVKMGRRDSLDLEVEVALGPAPGALEAGGSPGLEHVLPLLQQADELHQGDEQGKREGFQLLLKNKLVHGSRQDFLWRLARAYSDMCELAEEASEKKSHALSGEVFLQLLWLAPLPLITLEYDLRLYFPPQEHVDKAIALQPENPMTHFLLGRWCYQVSHLSWLEKKTATALSESPLSATVQDALQSFLKAEELKPGFSKAGRIYISKCYRELGKNPEAKQWVKLALELPDVTKEVINTSELF", "length": 444, "header": "tr|F1SSS8-1|F1SSS8_PIG Computationally mapped isoform of Regulator of microtubule dynamics protein 3 OS=Sus scrofa OX=9823 GN=RMDN3 PE=1 SV=5 CANONICAL=A0A4X1USF8-1" }, "locus": { "chromosome": "1", "start_pos": 130590546, "end_pos": 130574802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005264.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005264.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005137.5", "url": "https://www.ensembl.org/id/ENSSSCP00000005137.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A481CB65", "url": "https://www.uniprot.org/uniprotkb/A0A481CB65" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519696", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519696", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q1JQC5-1", "protein_name": "Regulator of microtubule dynamics protein 3", "gene_name": "RMDN3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSLGTLGGARAGLGLLLGTAAGLGFLCALYSQRWKRTQRRGQSQSQSNSLDYTQTSEPGRQVRPLRAAPGEAGDAAVLSSLPRGQEVVLDRLEFVLTSLVALRREVEELRSSLQGLAGQIVGEVRSHMEENQKVARRRRFPFARERSDSTGSSSVYFTAASGATFTDAESEGGYTTANAESDYERDSERESDGDGEDEVSCETVKMGRKDSLDLEVEVALGLEPEAPEAGGSPGQEDVMPLLQQADELHQGSEQGKREGFQLLLNNKLVHGSRQDFLWRLARAYSDMCELTEEASEKRSYALSGKEEAEVALEKGNENAECHQWYAVLCGQLAEHEGIQRRIQSGFSFKEHVDKAIALKPENPMAHFLLGRWCYQVSHLSWLEKKTATALSESPLGATVQDALSSFLKAEELQPGFSKAGRIYICKCYKELGKNPEAKEWMKLALELPNVTKEDSAFQKDLEELEVILGE", "length": 471 }, "evidence": [ { "id": "A0A4X1USF8", "url": "https://omabrowser.org/oma/group/A0A4X1USF8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UJU9-1", "protein_name": "Regulator of microtubule dynamics protein 3", "gene_name": "Rmdn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRLGALGGSRAGLGLLLGTAAGLGFLCVLYSQRWKRTQRHGRSHSLPNSLDYAQASERGRQVTQFRAIPGEAGDAAILPSLSQEGQEKVLDRLDFVLTSLMALRREVEELQRSLQGLAGEIVGEVRSHIEENQRVARRRRFPFARERSDSTGSSSVYFTASSGAALTDAESEGGYTTANAESDYERDSDKESGDAEDEVSCETVRMGRKDSLDLDVEAASSPAAAALEEDDSSGREDVQLVLLQADELHQGSKQDKREGFQLLLNNKLAYGSRQDFLWRLARAYSDMSDLTEEESGKKSYALNGKEEAEAALKKGDESAACHLWYAVLCGQLAEHEGISKRIQSGFSFKEHVDKAIELQPEDPRGHFLLGRWCYQVSHLNWLEKKTATALFESPLSATVQDALQSFLKAEELQPGFSKAGRVYISKCYRELGKNSEARKWMKLAQELPDVTNEDSAFQKDLEELEVILG", "length": 470 }, "evidence": [ { "id": "A0A4X1USF8", "url": "https://omabrowser.org/oma/group/A0A4X1USF8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5TYQ9-1", "protein_name": "Regulator of microtubule dynamics protein 3", "gene_name": "rmdn3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWLGRNATIGLGVGVTISTGLIALLIIKEAFRRRNRRLLLHNTRSALHNDAVDSSALTAAVQGLSPDQQQELRKTLDEVMKSVSSLRNEIAELREGLKDITTTIAEDVKKTVEESQRSRRRRSHMPRERTESMSSSSIYFTASAGIASAYDDSEVGYSTAYSNAESDYTDRETDRETDKDGEDEDRDSEEDEEQSCATVLTLRQEDSQAEEEEDEDSALMVESLTDIPIPELVLLLAQCDLLHAGDAEKKTEGFQLLMENRPLYADNAEFMWRLARAYSDMCETTENREEKKNYAEQGNYEAEAALTRNGLSADCHKWFAILARQSSQYDSIHGKLKSGHILKEHLDRALALCDDDPICFYLLGRWCLEVSSLSWLEKKAAATFYETSPTSSLNEALENFLKAEELNPGFSKTVRLYIAKCHKELGNLSEARNWVQLALNTPAGANEDSDVAALQTELKALIDSPTDQSTSSISN", "length": 476 }, "evidence": [ { "id": "A0A4X1USF8", "url": "https://omabrowser.org/oma/group/A0A4X1USF8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q66H15-1", "protein_name": "Regulator of microtubule dynamics protein 3", "gene_name": "Rmdn3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRLGALGGSRAGLGLLLGTAAGLGFLCVLYSQRWKRTQRHGRSQSLPNSLDYAQTSERGRQVTQLRAIPGEAGDAAMLSSLPQEGQEKVLDRLDFVLTSLMALRREVEELQRSLQGLAGEIVGEVRSHMEENQRVARRRRFPFARERSDSTGSSSVYFTASSGATLTDAESEGGYTTANAESDYERDSDKESEDAEDEVSCETVKMGRKDSLDLDMEVASSPASAALEDDDSSGLEDVQLLLQQADELHQGSEQNKQEGFQLLLNNKLAYGSRQDFLWRLARAYSDMTELTEEESEKKSYALNGKEEAEAALKKGDESAASHLWYAVLCGQLAEHEGISKRIQSGFSFKEHVDKAIELQPEDPRGHFLLGRWCYQVSHLSWLEKKTATALFESPLSATVQDALQSFLKAEELQPGFSKAGRVYISKCYRELGKNSEARKWLNLAQELPNITNEDSAFQKDLEELEVILGK", "length": 471 }, "evidence": [ { "id": "A0A4X1USF8", "url": "https://omabrowser.org/oma/group/A0A4X1USF8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96TC7-1", "protein_name": "Regulator of microtubule dynamics protein 3", "gene_name": "RMDN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRLGALGGARAGLGLLLGTAAGLGFLCLLYSQRWKRTQRHGRSQSLPNSLDYTQTSDPGRHVMLLRAVPGGAGDASVLPSLPREGQEKVLDRLDFVLTSLVALRREVEELRSSLRGLAGEIVGEVRCHMEENQRVARRRRFPFVRERSDSTGSSSVYFTASSGATFTDAESEGGYTTANAESDNERDSDKESEDGEDEVSCETVKMGRKDSLDLEEEAASGASSALEAGGSSGLEDVLPLLQQADELHRGDEQGKREGFQLLLNNKLVYGSRQDFLWRLARAYSDMCELTEEVSEKKSYALDGKEEAEAALEKGDESADCHLWYAVLCGQLAEHESIQRRIQSGFSFKEHVDKAIALQPENPMAHFLLGRWCYQVSHLSWLEKKTATALLESPLSATVEDALQSFLKAEELQPGFSKAGRVYISKCYRELGKNSEARWWMKLALELPDVTKEDLAIQKDLEELEVILRD", "length": 470 }, "evidence": [ { "id": "A0A4X1USF8", "url": "https://omabrowser.org/oma/group/A0A4X1USF8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" }, { "name": "organelle membrane contact site", "id": "GO:0044232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044232", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1USF8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1USF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UF11-1", "uniprot_ac": "A0A4X1UF11", "uniprot_id": "A0A4X1UF11_PIG", "mass": { "chemical_mass": 32915.0, "monoisotopic_mass": 32915.0 }, "refseq": { "ac": "XP_003121262", "name": "ethylmalonyl-CoA decarboxylase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121262" }, "gene_names": [ { "name": "ECHDC1", "type": "recommended", "evidence": [ { "id": "A0A4X1UF11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11" } ] }, { "name": "ECHDC1", "type": "synonym", "evidence": [ { "id": "XP_003121262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121262" } ] } ], "protein_names": [ { "name": "Ethylmalonyl-CoA decarboxylase", "type": "recommended", "evidence": [ { "id": "A0A4X1UF11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11/entry#names_and_taxonomy" } ] }, { "name": "4.1.1.94", "type": "synonym", "evidence": [ { "id": "A0A4X1UF11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11/entry#names_and_taxonomy" } ] }, { "name": "Enoyl-CoA hydratase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A4X1UF11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11/entry#names_and_taxonomy" } ] }, { "name": "Methylmalonyl-CoA decarboxylase", "type": "synonym", "evidence": [ { "id": "A0A4X1UF11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11/entry#names_and_taxonomy" } ] }, { "name": "ethylmalonyl-CoA decarboxylase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003121262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121262" } ] } ], "function": [ { "annotation": "Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Acts preferentially on (S)-ethylmalonyl-CoA but also has some activity on the (R)-isomer. Also has methylmalonyl-CoA decarboxylase activity at lower level.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UF11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11#function" }, { "database": "UniProtKB", "id": "ARBA00056546", "url": "https://www.uniprot.org/uniprotkb/ARBA00056546#function" }, { "database": "UniProtKB", "id": "F1S2X3", "url": "https://www.uniprot.org/uniprotkb/F1S2X3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UF11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ECHDC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11", "locus": { "chromosome": "1", "start_pos": 35909956, "end_pos": 35853125, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004216", "url": "https://www.ensembl.org/id/ENSSSCG00000004216" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004216", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004216", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06558", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06558", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512509", "url": "https://www.ncbi.nlm.nih.gov/gene/100512509", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512509", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512509", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FTICRPE", "url": "https://omabrowser.org/oma/group/FTICRPE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UF11", "url": "https://www.orthodb.org/?gene=A0A4X1UF11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11941", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11941", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11941:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11941:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00378", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00378", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003121262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121262", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "32131", "url": "https://www.rhea-db.org/rhea/32131", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "59540", "url": "https://www.rhea-db.org/rhea/59540", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "61340", "url": "https://www.rhea-db.org/rhea/61340", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UF11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UF11-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2X3", "url": "https://www.uniprot.org/uniprotkb/F1S2X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2X3-1", "url": "https://www.uniprot.org/uniprotkb/F1S2X3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLLTTSPVPIRTKFLHQIGLSLYNTSHGFHEEEVKKKLQQFPGGSVDLQKEENGLGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGVIVCGAKNTFSSGSDLNAVKALGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGRALGGGAEFTTACDFRLMTTESEIRFVHREMGIIPSWGGAARLVEIIGSRQALKVLSGALRLDSEKALHIGIADEVLQSSDETECLREAREWLQQFIKGPPEVIRALKKSISSGRELCLEEALQMERDLLGTVWGGPANLEAVARRGKFKK", "length": 300, "header": "tr|A0A4X1UF11-1|A0A4X1UF11_PIG Isoform 1 of Ethylmalonyl-CoA decarboxylase OS=Sus scrofa OX=9823 GN=ECHDC1 PE=1 SV=1 CANONICAL=A0A4X1UF11-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UF11-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11/entry#A0A4X1UF11-1", "sequence": { "sequence": "MASLLTTSPVPIRTKFLHQIGLSLYNTSHGFHEEEVKKKLQQFPGGSVDLQKEENGLGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGVIVCGAKNTFSSGSDLNAVKALGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGRALGGGAEFTTACDFRLMTTESEIRFVHREMGIIPSWGGAARLVEIIGSRQALKVLSGALRLDSEKALHIGIADEVLQSSDETECLREAREWLQQFIKGPPEVIRALKKSISSGRELCLEEALQMERDLLGTVWGGPANLEAVARRGKFKK", "length": 300, "header": "tr|A0A4X1UF11-1|A0A4X1UF11_PIG Isoform 1 of Ethylmalonyl-CoA decarboxylase OS=Sus scrofa OX=9823 GN=ECHDC1 PE=1 SV=1 CANONICAL=A0A4X1UF11-1" }, "locus": { "chromosome": "1", "start_pos": 35907919, "end_pos": 35880954, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057506.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057506.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036988.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036988.1" } ] } }, { "isoform_ac": "F1S2X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11/entry#F1S2X3-1", "sequence": { "sequence": "KELRQKMASLLTTSPVPIRTKFLHQIGLSLYNTSHGFHEEEVKKKLQQFPGGSVDLQKEENGLGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGVIVCGAKNTFSSGSDLNAVKALGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGRALGGGAEFTTACDFRLMTTESEIRFVHREMGIIPSWGGAARLVEIIGSRQALKVLSGALRLDSEKALHIGIADEVLQSSDETECLREAREWLQQFIKGPPEVIRALKKSISSGRELCLEEALQMERDLLGTVWGGPANLEAVARRGKFKK", "length": 306, "header": "tr|F1S2X3-1|A0A4X1UF11_PIG Computationally mapped isoform of Ethylmalonyl-CoA decarboxylase OS=Sus scrofa OX=9823 GN=ECHDC1 PE=1 SV=4 CANONICAL=A0A4X1UF11-1" }, "locus": { "chromosome": "1", "start_pos": 35907919, "end_pos": 35863415, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004659.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004659.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004552.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004552.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2X3", "url": "https://www.uniprot.org/uniprotkb/F1S2X3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512509", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512509", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XLG2-1", "protein_name": "Ethylmalonyl-CoA decarboxylase", "gene_name": "ECHDC1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVFLWRNLFQTTKARMLQQRRASLYNGAHDYDEELIKKKLQQFAGGSINLSKEHSGIGILTLNNSRLMNAFTGTMMLELQERVTELENWKDGKGLIICGAGNTFCSGSDLNAVKAISNSQDGMNMCMFMQNTLTRLMRLPLISIALIQGKALGGGAELTTACDFRLMTPGSEIRFVHKHMGLVPGWGGAARLVRIIGSRAALQLLSRAHGVDPERALHLGLSEGTLSSSDETGSLEEARAWLSQYTEGPASVIQAVKKVVTAGRELPLEAALRTEKDVFGTVWGGPANLEALTRRQKHK", "length": 300 }, "evidence": [ { "id": "A0A4X1UF11", "url": "https://omabrowser.org/oma/group/A0A4X1UF11/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7JDF5-1", "protein_name": "Ethylmalonyl-CoA decarboxylase", "gene_name": "Echdc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFSWMSIMSTEMAKSLLTTSLSARTKLLQTGVSLYNTSHGFHEEEVKKILEQFPGGSVDLQKNQNGIGILTLNNPNKMNAFSGVMMLQLLERVIELENWTEGKGLIVRGAKNTFCSGSDLNAVKALSTSENGVALSMFMQNTLTRFMRLPLISVALVQGWAMGGGAEFTTACDFRLMTMESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTLKLDSKKALNMGFVDEVLQSSDEAKALEEAQEWLEQFVSGPPEVIRGLKKSVCSGRELYLEEALQNERDVLGTLWGGPANLEAIAKRGKHTK", "length": 310 }, "evidence": [ { "id": "A0A4X1UF11", "url": "https://omabrowser.org/oma/group/A0A4X1UF11/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2HJD5-1", "protein_name": "Ethylmalonyl-CoA decarboxylase", "gene_name": "ECHDC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELKQEMASLLKTSPNAVKKRLLHQIGLSLYNTSHGFHEEEVKKKLEQFPGGSIDLQKENSGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIIRGAKNTFSSGSDLNAVKALGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGRALGGGAEVTTACDFRLMTTESEIRFVHKEMGIIPSWGGATRLVEIIGGRQALKVLSGALKLDSEKALNIGMVDDILPSSDETECLKEAQEWLQQFIKGPPEVIRALKKSVSSCKELCLEEALQRERDILGTVWGGPANLEAVARKGKFNK", "length": 306 }, "evidence": [ { "id": "A0A4X1UF11", "url": "https://omabrowser.org/oma/group/A0A4X1UF11/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D9V3-1", "protein_name": "Ethylmalonyl-CoA decarboxylase", "gene_name": "Echdc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRCEVNSKPISEYFGIPCENREMAKCLLTSSLSVRTKLLQTGVSLYNTSHGFHEEEVKKILEQFPGGSIDLLKKQNGIGILTLNNPNKMNAFSGVMMLQLLERVIELENWTEGKGLIIHGAKNTFCSGSDLNAVKALSTPESGVALSMFMQNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGTSRLVEIIGSRQALKVLSGTLKLDSKEALNIGLTDEVLQPSDETTALEQAQEWLEKFVSGPPQVIRGLKKSVCSARELYIEEALQNERDVLETLWGGPANLEAIAKKGKHTK", "length": 322 }, "evidence": [ { "id": "A0A4X1UF11", "url": "https://omabrowser.org/oma/group/A0A4X1UF11/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NTX5-1", "protein_name": "Ethylmalonyl-CoA decarboxylase", "gene_name": "ECHDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALKQEMAKSLLKTASLSGRTKLLHQTGLSLYSTSHGFYEEEVKKTLQQFPGGSIDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIAKKGKFNK", "length": 307 }, "evidence": [ { "id": "A0A4X1UF11", "url": "https://omabrowser.org/oma/group/A0A4X1UF11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UF11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UF11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "methyl/ethyl malonyl-CoA decarboxylase activity", "id": "GO:0004492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004492", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UF11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11" } ], "pmid": "" }, { "name": "carboxy-lyase activity", "id": "GO:0016831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016831", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UF11", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UF11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "32131", "name": "", "equation": "(2S)-ethylmalonyl-CoA + H(+) = butanoyl-CoA + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "32131", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32131" } ] }, { "id": "59540", "name": "", "equation": "(2R)-ethylmalonyl-CoA + H(+) = butanoyl-CoA + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "59540", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/59540" } ] }, { "id": "61340", "name": "", "equation": "(S)-methylmalonyl-CoA + H(+) = propanoyl-CoA + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "61340", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61340" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TRT1-1", "uniprot_ac": "A0A4X1TRT1", "uniprot_id": "A0A4X1TRT1_PIG", "mass": { "chemical_mass": 27415.0, "monoisotopic_mass": 27415.0 }, "refseq": {}, "gene_names": [ { "name": "CNOT8", "type": "recommended", "evidence": [ { "id": "A0A4X1TRT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ] } ], "protein_names": [ { "name": "poly(A)-specific ribonuclease", "type": "recommended", "evidence": [ { "id": "A0A4X1TRT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1/entry#names_and_taxonomy" } ] }, { "name": "3.1.13.4", "type": "synonym", "evidence": [ { "id": "A0A4X1TRT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CNOT8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1", "locus": { "chromosome": "16", "start_pos": 68329790, "end_pos": 68350260, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017067", "url": "https://www.ensembl.org/id/ENSSSCG00000017067" } ] } } ], "crossref": [ { "id": "A0A4X1TRT1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TRT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017067", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017067", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100525087", "url": "https://www.ncbi.nlm.nih.gov/gene/100525087", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039637", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039637", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525087", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525087", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIREVWS", "url": "https://omabrowser.org/oma/group/HIREVWS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F2Z590", "url": "https://www.orthodb.org/?gene=F2Z590", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10797", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10797", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-429947", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6804115", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804115", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TRT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX74", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QX74-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z590", "url": "https://www.uniprot.org/uniprotkb/F2Z590", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z590-1", "url": "https://www.uniprot.org/uniprotkb/F2Z590-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDYQYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ", "length": 238, "header": "tr|A0A4X1TRT1-1|A0A4X1TRT1_PIG Isoform 1 of poly(A)-specific ribonuclease OS=Sus scrofa OX=9823 GN=CNOT8 PE=3 SV=1 CANONICAL=A0A4X1TRT1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TRT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1/entry#A0A4X1TRT1-1", "sequence": { "sequence": "MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDYQYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ", "length": 238, "header": "tr|A0A4X1TRT1-1|A0A4X1TRT1_PIG Isoform 1 of poly(A)-specific ribonuclease OS=Sus scrofa OX=9823 GN=CNOT8 PE=3 SV=1 CANONICAL=A0A4X1TRT1-1" }, "locus": { "chromosome": "16", "start_pos": 68342082, "end_pos": 68331149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089970.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089970.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062882.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062882.1" } ] } }, { "isoform_ac": "A0A5G2QX74-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1/entry#A0A5G2QX74-1", "sequence": { "sequence": "MYSQDSIDLLANSGLQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ", "length": 186, "header": "tr|A0A5G2QX74-1|A0A4X1TRT1_PIG Computationally mapped isoform of poly(A)-specific ribonuclease OS=Sus scrofa OX=9823 GN=CNOT8 PE=3 SV=1 CANONICAL=A0A4X1TRT1-1" }, "locus": { "chromosome": "16", "start_pos": 68334749, "end_pos": 68331149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073113.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073113.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069476.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069476.1" } ] } }, { "isoform_ac": "F2Z590-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1/entry#F2Z590-1", "sequence": { "sequence": "MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDYQYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSGLQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ", "length": 292, "header": "tr|F2Z590-1|F2Z590_PIG Computationally mapped isoform of poly(A)-specific ribonuclease OS=Sus scrofa OX=9823 GN=CNOT8 PE=3 SV=1 CANONICAL=A0A4X1TRT1-1" }, "locus": { "chromosome": "16", "start_pos": 68342082, "end_pos": 68331149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018582.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018582.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018082.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018082.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QX74", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QX74" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525087", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525087", "resource": "KEGG Pathway" }, { "id": "R-SSC-429947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429947", "resource": "Reactome", "description": "Deadenylation of mRNA" }, { "id": "R-SSC-6804115", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804115", "resource": "Reactome", "description": "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9RW23-1", "protein_name": "poly(A)-specific ribonuclease", "gene_name": "CNOT8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDYQYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ", "length": 238 }, "evidence": [ { "id": "A0A4X1TRT1", "url": "https://omabrowser.org/oma/group/A0A4X1TRT1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54NG7-1", "protein_name": "poly(A)-specific ribonuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYHNFNYIDDENGHIKMLPSPVKPNGGKLRTPTSKATILTADIGHEIREVWAHNLEYEMSLIRELVDIYPCVAIDTEFPGFVNKPIESMRMYPDYNYQTLRSNVDLLKIIQFGITFSDSTGCLPVPTCTWQFNFKFSLKDDMYSPYAIELLKSCGIDFQRIEDYGIDVNDFSELFISSGIVLNDKIQWICFHGGYDFGYLLKVLSCSELPKSESDFFDLLRIYFPCIYDVKYLMKSCKNLKGGLSGLAEDLNVVRVGPQHQAGSDSLLTNSTFFKLREEFFENEIDDHKYKGILYGYNVSQNFHHNGHL", "length": 309 }, "evidence": [ { "id": "A0A4X1TRT1", "url": "https://omabrowser.org/oma/group/A0A4X1TRT1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9D8X5-1", "protein_name": "CCR4-NOT transcription complex subunit 8", "gene_name": "Cnot8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDYQYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSGLQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDCAQEKMSILAMINNMQQ", "length": 292 }, "evidence": [ { "id": "A0A4X1TRT1", "url": "https://omabrowser.org/oma/group/A0A4X1TRT1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SKZ2-1", "protein_name": "Probable CCR4-associated factor 1 homolog 7", "gene_name": "CAF1-7", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSLFLKDDSIQIREVWNDNLESEMALIREVVDDFPFVAMDTEFPGIVCRPVGTFKTNTEYHYETLKTNVNILKMIQLGLTFSDEKGNLPTCGTDNKYCIWQFNFREFDLESDIYATDSIELLRQSGIDFVKNNEFGIDSKRFAELLMSSGIVLNENVHWVTFHSGYDFGYLLKLLTCQNLPETQTGFFEMISVYFPRVYDIKHLMKFCNSLHGGLNKLAELLDVERVGICHQAGSDSLLTSCTFRKLQENFFIGSMEKYSGVLYGLGVENGQIVH", "length": 275 }, "evidence": [ { "id": "A0A4X1TRT1", "url": "https://omabrowser.org/oma/group/A0A4X1TRT1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UFF9-1", "protein_name": "CCR4-NOT transcription complex subunit 8", "gene_name": "CNOT8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDYQYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSGLQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ", "length": 292 }, "evidence": [ { "id": "A0A4X1TRT1", "url": "https://omabrowser.org/oma/group/A0A4X1TRT1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" }, { "name": "poly(A)-specific ribonuclease activity", "id": "GO:0004535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004535", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" }, { "name": "CCR4-NOT complex", "id": "GO:0030014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030014", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" }, { "name": "CCR4-NOT core complex", "id": "GO:0030015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030015", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" }, { "name": "miRNA-mediated gene silencing by mRNA destabilization", "id": "GO:0035279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035279", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:0000288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000288", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-429955", "name": "CCR4-NOT complex deadenylates mRNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-SSC-156803", "R-SSC-429861", "R-SSC-72573" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-429955", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429955" } ] }, { "id": "R-SSC-6798044", "name": "BTG2 binds CCR4-NOT complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6798044", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798044" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-156803", "participant_name": "PABPC1 [cytosol]", "crossref": [ { "id": "ENSSSCT00000032533", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000006063", "database": "ENSEMBL", "url": "" }, { "id": "98829", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000026891", "database": "ENSEMBL", "url": "" }, { "id": "F2Z557", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-429861", "participant_name": "PAIP1 [cytosol]", "crossref": [ { "id": "A0A287AHU1", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000043450", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000065777", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000016874", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-72573", "participant_name": "EIF4A1 [cytosol]", "crossref": [ { "id": "ENSSSCT00000032168", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000017957", "database": "ENSEMBL", "url": "" }, { "id": "98989", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000024903", "database": "ENSEMBL", "url": "" }, { "id": "A6M928", "database": "UniProt", "url": "" }, { "id": "NP_001093666.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VPA4-1", "uniprot_ac": "A0A4X1VPA4", "uniprot_id": "A0A4X1VPA4_PIG", "mass": { "chemical_mass": 80286.0, "monoisotopic_mass": 80286.0 }, "refseq": {}, "gene_names": [ { "name": "THOC1", "type": "recommended", "evidence": [ { "id": "A0A4X1VPA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ] } ], "protein_names": [ { "name": "THO complex subunit 1", "type": "recommended", "evidence": [ { "id": "A0A4X1VPA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4/entry#names_and_taxonomy" } ] }, { "name": "Nuclear matrix protein p84", "type": "synonym", "evidence": [ { "id": "A0A4X1VPA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "THOC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4", "locus": { "chromosome": "6", "start_pos": 106088021, "end_pos": 106040042, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000025653", "url": "https://www.ensembl.org/id/ENSSSCG00000025653" } ] } } ], "crossref": [ { "id": "A0A4X1VPA4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1VPA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000025653", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000025653", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08318", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08318", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100625217", "url": "https://www.ncbi.nlm.nih.gov/gene/100625217", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100625217", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625217", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LQREEMW", "url": "https://omabrowser.org/oma/group/LQREEMW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "I3LE05", "url": "https://www.orthodb.org/?gene=I3LE05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13265", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13265", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13265:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13265:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11957", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11957", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72187", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72187", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZIV5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZIV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZIV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VPA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEM7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LE05", "url": "https://www.uniprot.org/uniprotkb/I3LE05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LE05-1", "url": "https://www.uniprot.org/uniprotkb/I3LE05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPALNVEAALSSHGASPLVAPYLTSSSGAAARWRARAAEKMSPTPPLFSLPEARTRFTKSTRDALNNKNIKPLLNTFSQLPGSENEKKCTLDQAFRGVLEEEIINHSSCENVLAIISLAIGGVTEGICTASTPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSVSALNYCFREILLTDWLRNLDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQFNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDDEAPTTCSIPIDYNLYRKFWSLQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEELKTGGEHVYFAKFLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQLLSENPPDGERFSKMVEHILNTEENWNSWKNEGCPSFVKERTSDTKPTRVVRKRTAPEDFLGKGPNKKILMGNEELTRLWNLCPDNMEACKSETREYMPTLEEFFEEAIEQADPENMVENEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENESPDVRRDKPVTGDQIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKMRAKQLLVAWQDQEGVHATPENLISALNKSGLSDLAESLTNDNETNS", "length": 702, "header": "tr|A0A4X1VPA4-1|A0A4X1VPA4_PIG Isoform 1 of THO complex subunit 1 OS=Sus scrofa OX=9823 GN=THOC1 PE=1 SV=1 CANONICAL=A0A4X1VPA4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4/entry#A0A286ZIV5-1", "sequence": { "sequence": "MGPALNVEAALSSHGASPLVAPYLTSSSGAAARWRARAAEKMSPTPPLFSLPEARTRFTKSTRDALNNKNIKPLLNTFSQLPGSENEKKCTLDQAFRGVLEEEIINHSSCENVLAIISLAIGGVTEGICTASTPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSVSALNYCFREILLTDWLRNLDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQFNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDDEAPTTCSIPIDYNLYRKFWSLQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEELKTGGEHVYFAKFLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQLLSENPPDGERFSKMVEHILNTEENWNSWKNEGCPSFVKESEELTRLWNLCPDNMEACKSETREYMPTLEEFFEEAIEQADPENMVENEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENESPDVRRDKPVTGDQIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKMRAKQLLVAWQDQEGVHATPENLISALNKSGLSDLAESLTNDNETNS", "length": 670, "header": "tr|A0A286ZIV5-1|A0A4X1VPA4_PIG Computationally mapped isoform of THO complex subunit 1 OS=Sus scrofa OX=9823 GN=THOC1 PE=1 SV=2 CANONICAL=A0A4X1VPA4-1" }, "locus": { "chromosome": "6", "start_pos": 106087921, "end_pos": 106040522, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041337.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041337.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031412.2", "url": "https://www.ensembl.org/id/ENSSSCP00000031412.2" } ] } }, { "isoform_ac": "A0A4X1VPA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4/entry#A0A4X1VPA4-1", "sequence": { "sequence": "MGPALNVEAALSSHGASPLVAPYLTSSSGAAARWRARAAEKMSPTPPLFSLPEARTRFTKSTRDALNNKNIKPLLNTFSQLPGSENEKKCTLDQAFRGVLEEEIINHSSCENVLAIISLAIGGVTEGICTASTPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSVSALNYCFREILLTDWLRNLDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQFNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDDEAPTTCSIPIDYNLYRKFWSLQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEELKTGGEHVYFAKFLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQLLSENPPDGERFSKMVEHILNTEENWNSWKNEGCPSFVKERTSDTKPTRVVRKRTAPEDFLGKGPNKKILMGNEELTRLWNLCPDNMEACKSETREYMPTLEEFFEEAIEQADPENMVENEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENESPDVRRDKPVTGDQIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKMRAKQLLVAWQDQEGVHATPENLISALNKSGLSDLAESLTNDNETNS", "length": 702, "header": "tr|A0A4X1VPA4-1|A0A4X1VPA4_PIG Isoform 1 of THO complex subunit 1 OS=Sus scrofa OX=9823 GN=THOC1 PE=1 SV=1 CANONICAL=A0A4X1VPA4-1" }, "locus": { "chromosome": "6", "start_pos": 106087921, "end_pos": 106040522, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069951.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069951.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068178.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068178.1" } ] } }, { "isoform_ac": "A0A5G2QRI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4/entry#A0A5G2QRI4-1", "sequence": { "sequence": "KSTRDALNNKNIKPLLNTFSQLPGSENEKKCTLDQAFRGVLEEEIINHSSCENVLAIISLAIGGVTEGICTASTPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQFNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDDEAPTTCSIPIDYNLYRKFWSLQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEELKTGGEHVYFAKFLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQVSSSRNKPMIEKMKI", "length": 359, "header": "tr|A0A5G2QRI4-1|A0A4X1VPA4_PIG Computationally mapped isoform of THO complex subunit 1 OS=Sus scrofa OX=9823 GN=THOC1 PE=1 SV=2 CANONICAL=A0A4X1VPA4-1" }, "locus": { "chromosome": "6", "start_pos": 106077798, "end_pos": 106043167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076868.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076868.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066672.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066672.2" } ] } }, { "isoform_ac": "A0A8W4FEM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4/entry#A0A8W4FEM7-1", "sequence": { "sequence": "MSPTPPLFSLPEARTRFTKSTRDALNNKNIKPLLNTFSQLPGSENEKKCTLDQAFRGVLEEEIVFVPHLHLLYCWEMFWIVFLWISVTQYSLLWKKMLLLGNQIHSILLGKIIYYVCVMISYEDYQNPRIQFSVDEFNCFWPGFSLYLRSQVLTCRVSLIWKMSLFSIPTSRKAHWVRSTLRIEKKEWM", "length": 189, "header": "tr|A0A8W4FEM7-1|A0A4X1VPA4_PIG Computationally mapped isoform of THO complex subunit 1 OS=Sus scrofa OX=9823 GN=THOC1 PE=1 SV=1 CANONICAL=A0A4X1VPA4-1" }, "locus": { "chromosome": "6", "start_pos": 106060703, "end_pos": 106040645, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103366.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103366.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077766.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077766.1" } ] } }, { "isoform_ac": "I3LE05-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4/entry#I3LE05-1", "sequence": { "sequence": "MGPALNVEAALSSHGASPLVAPYLTSSSGAAARWRARAAEKMSPTPPLFSLPEARTRFTKSTRDALNNKNIKPLLNTFSQLPGSENEKKCTLDQAFRGVLEEEIINHSSCENVLAIISLAIGGVTEGICTASTPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQFNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDDEAPTTCSIPIDYNLYRKFWSLQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEELKTGGEHVYFAKFLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQLLSENPPDGERFSKMVEHILNTEENWNSWKNEGCPSFVKERTSDTKPTRVVRKRTAPEDFLGKGPNKKILMGNEELTRLWNLCPDNMEACKSETREYMPTLEEFFEEAIEQADPENMVENEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENESPDVRRDKPVTGDQIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKMRAKQLLVAWQDQEGVHATPENLISALNKSGLSDLAESLTNDNETNS", "length": 698, "header": "tr|I3LE05-1|A0A4X1VPA4_PIG Computationally mapped isoform of THO complex subunit 1 OS=Sus scrofa OX=9823 GN=THOC1 PE=1 SV=2 CANONICAL=A0A4X1VPA4-1" }, "locus": { "chromosome": "6", "start_pos": 106087921, "end_pos": 106040522, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029403.4", "url": "https://www.ensembl.org/id/ENSSSCT00000029403.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022290.2", "url": "https://www.ensembl.org/id/ENSSSCP00000022290.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 45, "start_aa": "Thr", "end_pos": 45, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr45", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRI4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRI4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100625217", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625217", "resource": "KEGG Pathway" }, { "id": "R-SSC-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-SSC-72187", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72187", "resource": "Reactome", "description": "mRNA 3'-end processing" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MJV3-1", "protein_name": "THO complex subunit 1", "gene_name": "THOC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSPTPPLFSLPEARTRFTKSTREALNSKNIKPLLNTFSQLPGSENEKKCTLDQAFRGVLEEEIINHSSCENVLAIISLAIGGVTEGICTASTPFVLLGDVLDCLPLDQCDTIFTFVERNVATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQFNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDDEAPTTCSIPIDYNLYRKFWSLQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEELKTGGEHVYFAKFLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQLLSENPPDGERFSKMVEHILNTEENWNSWKNEGCPSFVKERTSDSKPTRAVRKRAAPEDFLGKGPSKKILMGNDELTRLWNLCPDNMEACKSETREYMPTLEEFFEEAIEQADPENMVESEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENESPDVRRDKPVTGDQIEVFANKLGEQWKVLAPYLEMKDSEIRQIECDSEDMKMRAKQLLVAWQDQEGVHATPENLINALNKSGLSDLAESLTNDNETNS", "length": 657 }, "evidence": [ { "id": "A0A4X1VPA4", "url": "https://omabrowser.org/oma/group/A0A4X1VPA4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P59924-1", "protein_name": "THO complex subunit 1", "gene_name": "Thoc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEYYSAIKNNDIMKFLSKWMGVEEIIPKAGKEPDVLQQTMDTENVVYLHNGLLLSYNDFMKFIGKWMELEYIILSEFCEERASYTKLKRGVWKRSAPEDFLDKRPNKKILIGNEELTRLWNLCPDNMEACKLETREYMPILEEFFEEAIEQADAENMVESEYKAINNSNYGWSTLRFLAWRSPHFFQPTNQQFKNMTEYLENMVIKLAKELPPHSEEIKTGEDEDEEDNDALLKENESPDVRQDKPITGERIESLTNKLDEQWKILAPYLEIKDSDIRQIECYSEDMKKRAKQLLVAWKDQEGVHETTDNLIGALNKSGLSDLAESLTNDTETNSYLLSLLFY", "length": 343 }, "evidence": [ { "id": "A0A4X1VPA4", "url": "https://omabrowser.org/oma/group/A0A4X1VPA4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R3N6-1", "protein_name": "THO complex subunit 1", "gene_name": "Thoc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPTPALFSLPEARTRFTKSTREALNNKNIKPLLTAFSQLPGSENEKKCTLDQAFRGVLEEEIINHSACENVLAIISLAIGGVTESVCTASTPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQFNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDDEAPTTCSIPIDYNLYRKFWSLQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEELKTGGEHVYFAKFLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQLLSENPPDGERFSKMVEHILNTEENWNSWKNEGCPSFVKERASDTKPTRVVRKRAAPEDFLGKGPNKKILIGNEELTRLWNLCPDNMEACKSETREYMPTLEEFFEEAIEQADPENMVESEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENESPDVRRDKPITGEQIESFANKLGEQWKILAPYLEIKDSDIRQIECDSEDMKMRAKQLLVAWQDQEGVHATTDNLISALNKSGLSDLAESLTNDTETNS", "length": 657 }, "evidence": [ { "id": "A0A4X1VPA4", "url": "https://omabrowser.org/oma/group/A0A4X1VPA4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VNI8-1", "protein_name": "Hpr1", "gene_name": "Hpr1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTAVEVANTAPEKLANYFALQSAFEKALELAITDGKVELLVKEYNRFPANTEHDKRLPMDHAFRVLLMKRLDEDVSRIGELVRLSVEATRAEIVSNTIPVVLLIDTFDVVTLDKCQKIFQFVEDMVEVWKEEIFFSSCKNNILRMCNDLLRRLSRTQNTVFCGRIQLFLSKFFPFSERSGLNIVSEFNLDNFTEYGLDSKDHDESDNKELEDTAEDIPLKIDYDLYCKFWSLQDFFRNPNQCYNKPQWKMFQMHADNILQSFSSFKLEDVRQSSNENASGTDQAMDVDEEAVDTTAVSSVIKANHFFAKFLTNPKLLALQLSDANFRRAVLVQFLILFQYLQVSVKFKSDTQTLTADQADFIKETESRVYKLLEETPPYGKRFSRTVYHMLAREEMWNNWKNEGCKEFKKPEEPTLSEEDSKPTPNKRPRRPLGDALRDASRSGKFYLGNDNLTRLWNYSPDNLQACKSEQRNFLPLLETYLETPHEKVDPAFEWRALRLLARQTPHFFTSLSQPSSKISDYLEQVRKRLIRDKEPKPAALLSNNSSENNFGLSVNNVHTEGEQDATVALQDGEPEQDLEVEDNEPVVEEVDEVPAHEKPLMVTKEHIEEVAPLIGEPWMKVGKKIGFTNDELLFFQMEHPTANVACVKMLTNWISDDDDATLENWAYMLEGLEMNKAAEAVKAIIEREKSGSTAAFCLR", "length": 701 }, "evidence": [ { "id": "A0A4X1VPA4", "url": "https://omabrowser.org/oma/group/A0A4X1VPA4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "THO complex part of transcription export complex", "id": "GO:0000445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000445", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VPA4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 683, "end_pos": 685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 698, "end_pos": 700, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1VPA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VPA4" }, { "id": "PS50017", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Death", "eco_id": "ECO_0000259", "start_pos": 615, "end_pos": 698, "start_aa": "Thr", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 45 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 533, "end_pos": 535 }, { "start_pos": 603, "end_pos": 605 }, { "start_pos": 683, "end_pos": 685 }, { "start_pos": 698, "end_pos": 700 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UKW3-1", "uniprot_ac": "A0A4X1UKW3", "uniprot_id": "A0A4X1UKW3_PIG", "mass": { "chemical_mass": 67225.0, "monoisotopic_mass": 67225.0 }, "refseq": { "ac": "XP_020948300", "name": "E3 SUMO-protein ligase PIAS2 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948300" }, "gene_names": [ { "name": "PIAS2", "type": "recommended", "evidence": [ { "id": "A0A4X1UKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ] }, { "name": "PIAS2", "type": "synonym", "evidence": [ { "id": "XP_020948300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948300" } ] } ], "protein_names": [ { "name": "E3 SUMO-protein ligase PIAS2 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_020948300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948300" } ] }, { "name": "Protein inhibitor of activated STAT 2", "type": "synonym", "evidence": [ { "id": "A0A4X1UKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PIAS2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3", "locus": { "chromosome": "1", "start_pos": 96441676, "end_pos": 96545780, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034730", "url": "https://www.ensembl.org/id/ENSSSCG00000034730" } ] } } ], "crossref": [ { "id": "A0A4X1UKW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UKW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034730", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034730", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16819", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16819", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100627995", "url": "https://www.ncbi.nlm.nih.gov/gene/100627995", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10782", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10782", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10782:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10782:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02891", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02891", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3232118", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3232118", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3232142", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3232142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4090294", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4090294", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020948300", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948300", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZL24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZL24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZL24-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZL24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AP61", "url": "https://www.uniprot.org/uniprotkb/A0A287AP61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AP61-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AP61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UKW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1M6L2", "url": "https://www.uniprot.org/uniprotkb/A0A8D1M6L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1M6L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1M6L2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFSLDGSSSPVEPDLAVAGIHSLPSTSVTPHSPPSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIETSSVLSKPCSVTVANEASKKKVDVIDLTVESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSPHESTTHVSSSSSRSETGVITSSGSNIPDIISLD", "length": 612, "header": "tr|A0A4X1UKW3-1|A0A4X1UKW3_PIG Isoform 1 of Protein inhibitor of activated STAT 2 OS=Sus scrofa OX=9823 GN=PIAS2 PE=3 SV=1 CANONICAL=A0A4X1UKW3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZL24-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3/entry#A0A286ZL24-1", "sequence": { "sequence": "MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFSLDGSSSPVEPDLAVAGIHSLPSTSVTPHSPPSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIETSSVLSKPCSVTVANEASKKKVDVIDLTVESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSPHESTTHVSSSSSRSETGVITSSGSNIPDIISLD", "length": 576, "header": "tr|A0A286ZL24-1|A0A4X1UKW3_PIG Computationally mapped isoform of Protein inhibitor of activated STAT 2 OS=Sus scrofa OX=9823 GN=PIAS2 PE=3 SV=1 CANONICAL=A0A4X1UKW3-1" }, "locus": { "chromosome": "1", "start_pos": 96545604, "end_pos": 96445201, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046962.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046962.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032269.1", "url": "https://www.ensembl.org/id/ENSSSCP00000032269.1" } ] } }, { "isoform_ac": "A0A287AP61-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3/entry#A0A287AP61-1", "sequence": { "sequence": "MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFSLDGSSSPVEPDLAVAGIHSLPSTSVTPHSPPSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIETSSVLSKPCSVTVANEASKKKVDVIDLTVESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDPQSHLTLNRKQYVCHHHQPP", "length": 580, "header": "tr|A0A287AP61-1|A0A4X1UKW3_PIG Computationally mapped isoform of Protein inhibitor of activated STAT 2 OS=Sus scrofa OX=9823 GN=PIAS2 PE=3 SV=2 CANONICAL=A0A4X1UKW3-1" }, "locus": { "chromosome": "1", "start_pos": 96545604, "end_pos": 96445298, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038005.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038005.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045802.2", "url": "https://www.ensembl.org/id/ENSSSCP00000045802.2" } ] } }, { "isoform_ac": "A0A4X1UKW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3/entry#A0A4X1UKW3-1", "sequence": { "sequence": "MVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFSLDGSSSPVEPDLAVAGIHSLPSTSVTPHSPPSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIETSSVLSKPCSVTVANEASKKKVDVIDLTVESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSPHESTTHVSSSSSRSETGVITSSGSNIPDIISLD", "length": 612, "header": "tr|A0A4X1UKW3-1|A0A4X1UKW3_PIG Isoform 1 of Protein inhibitor of activated STAT 2 OS=Sus scrofa OX=9823 GN=PIAS2 PE=3 SV=1 CANONICAL=A0A4X1UKW3-1" }, "locus": { "chromosome": "1", "start_pos": 96516006, "end_pos": 96445201, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090574.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090574.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070149.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070149.1" } ] } }, { "isoform_ac": "A0A8D1M6L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3/entry#A0A8D1M6L2-1", "sequence": { "sequence": "MVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFSLDGSSSPVEPDLAVAGIHSLPSTSVTPHSPPSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIETSSVLSKPCSVTVANEASKKKVDVIDLTVESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTPISSMSSDLPGGRRRNDINNELQLGSSSDTVQQ", "length": 563, "header": "tr|A0A8D1M6L2-1|A0A4X1UKW3_PIG Computationally mapped isoform of Protein inhibitor of activated STAT 2 OS=Sus scrofa OX=9823 GN=PIAS2 PE=3 SV=1 CANONICAL=A0A4X1UKW3-1" }, "locus": { "chromosome": "1", "start_pos": 96516006, "end_pos": 96451145, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063240.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063240.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035482.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035482.2" } ] } }, { "isoform_ac": "A0A8W4FMQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3/entry#A0A8W4FMQ8-1", "sequence": { "sequence": "MVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFSLDGSSSPVEPDLAVAGIHSLPSTSVTPHSPPSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIETSSVLSKPCSVTVANEASKKKVDVIDLTVESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDPQESFVKAAFLDP", "length": 564, "header": "tr|A0A8W4FMQ8-1|A0A4X1UKW3_PIG Computationally mapped isoform of Protein inhibitor of activated STAT 2 OS=Sus scrofa OX=9823 GN=PIAS2 PE=3 SV=1 CANONICAL=A0A4X1UKW3-1" }, "locus": { "chromosome": "1", "start_pos": 96516006, "end_pos": 96445142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099788.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099788.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080776.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080776.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1M6L2", "url": "https://www.uniprot.org/uniprotkb/A0A8D1M6L2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3232118", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3232118", "resource": "Reactome", "description": "SUMOylation of transcription factors" }, { "id": "R-SSC-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-SSC-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" }, { "id": "R-SSC-4090294", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4090294", "resource": "Reactome", "description": "SUMOylation of intracellular receptors" }, { "id": "R-SSC-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" }, { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" }, { "name": "negative regulation of androgen receptor signaling pathway", "id": "GO:0060766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060766", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" }, { "name": "SUMO ligase activity", "id": "GO:0061665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061665", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UKW3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" }, { "id": "PS51466", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51466" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PINIT", "eco_id": "ECO_0000259", "start_pos": 125, "end_pos": 290, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1UKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 36, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1UKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UKW3" }, { "id": "PS51044", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51044" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SP-RING-type", "eco_id": "ECO_0000259", "start_pos": 322, "end_pos": 403, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 279, "end_pos": 281 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TSB0-1", "uniprot_ac": "A0A4X1TSB0", "uniprot_id": "A0A4X1TSB0_PIG", "mass": { "chemical_mass": 37504.0, "monoisotopic_mass": 37504.0 }, "refseq": { "ac": "NP_001230478", "name": "exostosin-like 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230478" }, "gene_names": [ { "name": "EXTL2", "type": "recommended", "evidence": [ { "id": "A0A4X1TSB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ] }, { "name": "EXTL2", "type": "synonym", "evidence": [ { "id": "NP_001230478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230478" } ] } ], "protein_names": [ { "name": "Exostosin-like 2", "type": "recommended", "evidence": [ { "id": "A0A4X1TSB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.223", "type": "synonym", "evidence": [ { "id": "A0A4X1TSB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0/entry#names_and_taxonomy" } ] }, { "name": "Alpha-1,4-N-acetylhexosaminyltransferase EXTL2", "type": "synonym", "evidence": [ { "id": "A0A4X1TSB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0/entry#names_and_taxonomy" } ] }, { "name": "Alpha-GalNAcT EXTL2", "type": "synonym", "evidence": [ { "id": "A0A4X1TSB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0/entry#names_and_taxonomy" } ] }, { "name": "EXT-related protein 2", "type": "synonym", "evidence": [ { "id": "A0A4X1TSB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0/entry#names_and_taxonomy" } ] }, { "name": "Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase", "type": "synonym", "evidence": [ { "id": "A0A4X1TSB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0/entry#names_and_taxonomy" } ] }, { "name": "exostoses (multiple)-like 2", "type": "synonym", "evidence": [ { "id": "NP_001230478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230478" } ] }, { "name": "exostosin-like 2", "type": "synonym", "evidence": [ { "id": "NP_001230478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230478" } ] } ], "function": [ { "annotation": "Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSD3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSD3#function" }, { "database": "UniProtKB", "id": "ARBA00060061", "url": "https://www.uniprot.org/uniprotkb/ARBA00060061#function" }, { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0#function" }, { "database": "UniProtKB", "id": "F1S568", "url": "https://www.uniprot.org/uniprotkb/F1S568#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EXTL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0", "locus": { "chromosome": "4", "start_pos": 117420704, "end_pos": 117396615, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006861", "url": "https://www.ensembl.org/id/ENSSSCG00000006861" } ] } } ], "crossref": [ { "id": "A0A4X1TSB0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TSB0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006861", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006861", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100155305", "url": "https://www.ncbi.nlm.nih.gov/gene/100155305", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155305", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155305", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TSB0", "url": "https://www.orthodb.org/?gene=A0A4X1TSB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47844", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47844", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47844:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47844:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001230478", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230478", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16221", "url": "https://www.rhea-db.org/rhea/16221", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZNT6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZNT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TSB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TSD3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TSD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S568", "url": "https://www.uniprot.org/uniprotkb/F1S568", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S568-1", "url": "https://www.uniprot.org/uniprotkb/F1S568-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRCYHICKVPGRVMGIRVLRFSLVVILVLLLVAGALTTLLPNIKEDKMLALRREIKSQGKSPLDSFTLIMQTYNRTDLLLRLLNHYQAVPNLHKVIVVWNNVGEKGPDELWNSLGPHPVPVIFKPQTANRMRNRLQVFPELETSAVLMVDDDMLISAQDLVFAFSVWQQFPDQIVGFVPRKHVATASGVYSYGGFELHTPGFGNGDHYSLVLIGASFFNSKYLDLFQRQPAAVHALLDETQNCDDIAMNFLIAKHTGKTSGVFVKPVNMYNLEKETNGGYSGMWHRAEHFLQRSYCINKLVHIYDSMPLRYSNIMISQFGFPYANHKSKM", "length": 330, "header": "tr|A0A4X1TSB0-1|A0A4X1TSB0_PIG Isoform 1 of Exostosin-like 2 OS=Sus scrofa OX=9823 GN=EXTL2 PE=1 SV=1 CANONICAL=A0A4X1TSB0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZNT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0/entry#A0A286ZNT6-1", "sequence": { "sequence": "MRCYHICKVPGRVMGIRVLRFSLVVILVLLLVAGALTTLLPNIKEDKMLALRREIKSQGKSPLDSFTLIMQTYNRTDLLLRLLNHYQAVPNLHKVIVVWNNVGEKGPDELWNSLGPHPVPVIFKPQTANRMRNRLQVFPELETSAIS", "length": 147, "header": "tr|A0A286ZNT6-1|A0A4X1TSB0_PIG Computationally mapped isoform of Exostosin-like 2 OS=Sus scrofa OX=9823 GN=EXTL2 PE=1 SV=2 CANONICAL=A0A4X1TSB0-1" }, "locus": { "chromosome": "4", "start_pos": 117416957, "end_pos": 117400016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056184.2", "url": "https://www.ensembl.org/id/ENSSSCT00000056184.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033246.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033246.2" } ] } }, { "isoform_ac": "A0A4X1TSB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0/entry#A0A4X1TSB0-1", "sequence": { "sequence": "MRCYHICKVPGRVMGIRVLRFSLVVILVLLLVAGALTTLLPNIKEDKMLALRREIKSQGKSPLDSFTLIMQTYNRTDLLLRLLNHYQAVPNLHKVIVVWNNVGEKGPDELWNSLGPHPVPVIFKPQTANRMRNRLQVFPELETSAVLMVDDDMLISAQDLVFAFSVWQQFPDQIVGFVPRKHVATASGVYSYGGFELHTPGFGNGDHYSLVLIGASFFNSKYLDLFQRQPAAVHALLDETQNCDDIAMNFLIAKHTGKTSGVFVKPVNMYNLEKETNGGYSGMWHRAEHFLQRSYCINKLVHIYDSMPLRYSNIMISQFGFPYANHKSKM", "length": 330, "header": "tr|A0A4X1TSB0-1|A0A4X1TSB0_PIG Isoform 1 of Exostosin-like 2 OS=Sus scrofa OX=9823 GN=EXTL2 PE=1 SV=1 CANONICAL=A0A4X1TSB0-1" }, "locus": { "chromosome": "4", "start_pos": 117417435, "end_pos": 117400016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065082.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065082.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054346.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054346.1" } ] } }, { "isoform_ac": "A0A4X1TSD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0/entry#A0A4X1TSD3-1", "sequence": { "sequence": "MCYHICKVPGRVMGIRVLRFSLVVILVLLLVAGALTTLLPNIKEDKMLALRREIKSQGKSPLDSFTLIMQTYNRTDLLLRLLNHYQAVPNLHKVIVVWNNVGEKGPDELWNSLGPHPVPVIFKPQTANRMRNRLQVFPELETSAVLMVDDDMLISAQDLVFAFSVWQQFPDQIVGFVPRKHVATASGVYSYGGFELHTPGFGNGDHYSLVLIGASFFNSKYLDLFQRQPAAVHALLDETQNCDDIAMNFLIAKHTGKTSGVFVKPVNMYNLEKETNGGYSGMWHRAEHFLQRSYCINKLVHIYDSMPLRYSNIMISQFGFPYANHKSKM", "length": 329, "header": "tr|A0A4X1TSD3-1|A0A4X1TSD3_PIG Computationally mapped isoform of Exostosin-like 2 OS=Sus scrofa OX=9823 GN=EXTL2 PE=1 SV=1 CANONICAL=A0A4X1TSB0-1" }, "locus": { "chromosome": "4", "start_pos": 117417435, "end_pos": 117412452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057849.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057849.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056671.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056671.2" } ] } }, { "isoform_ac": "F1S568-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0/entry#F1S568-1", "sequence": { "sequence": "RCYHICKVPGRVMGIRVLRFSLVVILVLLLVAGALTTLLPNIKEDKMLALRREIKSQGKSPLDSFTLIMQTYNRTDLLLRLLNHYQAVPNLHKVIVVWNNVGEKGPDELWNSLGPHPVPVIFKPQTANRMRNRLQVFPELETSAVLMVDDDMLISAQDLVFAFSVWQQFPDQIVGFVPRKHVATASGVYSYGGFELHTPGFGNGDHYSLVLIGASFFNSKYLDLFQRQPAAVHALLDETQNCDDIAMNFLIAKHTGKTSGVFVKPVNMYNLEKETNGGYSGMWHRAEHFLQRSYCINKLVHIYDSMPLRYSNIMISQFGFLIFKFFFF", "length": 328, "header": "tr|F1S568-1|A0A4X1TSB0_PIG Computationally mapped isoform of Exostosin-like 2 OS=Sus scrofa OX=9823 GN=EXTL2 PE=1 SV=3 CANONICAL=A0A4X1TSB0-1" }, "locus": { "chromosome": "4", "start_pos": 117417536, "end_pos": 117412489, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007514.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007514.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007315.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007315.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZNT6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNT6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155305", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155305", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ], "pmid": "" }, { "name": "glycosaminoglycan binding", "id": "GO:0005539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005539", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ], "pmid": "" }, { "name": "glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0047237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047237", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ], "pmid": "" }, { "name": "glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "id": "GO:0001888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001888", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ], "pmid": "" }, { "name": "alpha-1,4-N-acetylgalactosaminyltransferase activity", "id": "GO:0035248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035248", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "carbohydrate derivative metabolic process", "id": "GO:1901135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901135", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ], "pmid": "" }, { "name": "N-acetylglucosamine metabolic process", "id": "GO:0006044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006044", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ], "pmid": "" }, { "name": "UDP-N-acetylgalactosamine metabolic process", "id": "GO:0019276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019276", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSB0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16221", "name": "", "equation": "3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16221", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16221" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TSB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSB0" }, { "id": "PF09258", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09258" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl transferase 64", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 321, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U6K5-1", "uniprot_ac": "A0A4X1U6K5", "uniprot_id": "A0A4X1U6K5_PIG", "mass": { "chemical_mass": 14809.0, "monoisotopic_mass": 14809.0 }, "refseq": {}, "gene_names": [ { "name": "YPEL3", "type": "recommended", "evidence": [ { "id": "A0A4X1U6K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5" } ] }, { "name": "YPEL", "type": "synonym", "evidence": [ { "id": "A0A4X1U6K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5" } ] } ], "protein_names": [ { "name": "Protein yippee-like", "type": "recommended", "evidence": [ { "id": "A0A4X1U6K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6K5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "YPEL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5", "locus": { "chromosome": "3", "start_pos": 18278002, "end_pos": 18281298, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000035430", "url": "https://www.ensembl.org/id/ENSSSCG00000035430" } ] } } ], "crossref": [ { "id": "A0A4X1U6K5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U6K5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000035430", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035430", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100624297", "url": "https://www.ncbi.nlm.nih.gov/gene/100624297", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624297", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624297", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CADCRQV", "url": "https://omabrowser.org/oma/group/CADCRQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QD97", "url": "https://www.orthodb.org/?gene=A0A5G2QD97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13848", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13848", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZRH4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZRH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U6K5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U6K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QD97", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QD97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QD97-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QD97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2C1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2C1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCVAQVLTAPLLPSLQALGSLCSPWAAPRVGPLPPAPAMVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYVSQPLTPGQ", "length": 137, "header": "tr|A0A4X1U6K5-1|A0A4X1U6K5_PIG Isoform 1 of Protein yippee-like OS=Sus scrofa OX=9823 GN=YPEL3 PE=3 SV=2 CANONICAL=A0A4X1U6K5-1" }, "isoforms": [ { "isoform_ac": "A0A286ZRH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5/entry#A0A286ZRH4-1", "sequence": { "sequence": "MVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQKYKEGKYIIELNHMIKDNGWD", "length": 119, "header": "tr|A0A286ZRH4-1|A0A4X1U6K5_PIG Computationally mapped isoform of Protein yippee-like OS=Sus scrofa OX=9823 GN=YPEL3 PE=3 SV=1 CANONICAL=A0A4X1U6K5-1" }, "locus": { "chromosome": "3", "start_pos": 18280435, "end_pos": 18278402, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043045.2", "url": "https://www.ensembl.org/id/ENSSSCT00000043045.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034066.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034066.1" } ] } }, { "isoform_ac": "A0A4X1U6K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5/entry#A0A4X1U6K5-1", "sequence": { "sequence": "MCVAQVLTAPLLPSLQALGSLCSPWAAPRVGPLPPAPAMVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYVSQPLTPGQ", "length": 137, "header": "tr|A0A4X1U6K5-1|A0A4X1U6K5_PIG Isoform 1 of Protein yippee-like OS=Sus scrofa OX=9823 GN=YPEL3 PE=3 SV=2 CANONICAL=A0A4X1U6K5-1" }, "locus": { "chromosome": "3", "start_pos": 18280549, "end_pos": 18279814, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078367.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078367.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064240.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064240.2" } ] } }, { "isoform_ac": "A0A5G2QD97-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5/entry#A0A5G2QD97-1", "sequence": { "sequence": "MVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYLLLPFRGSEKLPKAPQQHGAWNRPSRAARSTKRGSTSLNSTT", "length": 132, "header": "tr|A0A5G2QD97-1|A0A4X1U6K5_PIG Computationally mapped isoform of Protein yippee-like OS=Sus scrofa OX=9823 GN=YPEL3 PE=3 SV=1 CANONICAL=A0A4X1U6K5-1" }, "locus": { "chromosome": "3", "start_pos": 18280435, "end_pos": 18278425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077261.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077261.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061576.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061576.1" } ] } }, { "isoform_ac": "A0A5G2R2C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5/entry#A0A5G2R2C1-1", "sequence": { "sequence": "MVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVNRPSRAARSTKRGSTSLNSTT", "length": 75, "header": "tr|A0A5G2R2C1-1|A0A4X1U6K5_PIG Computationally mapped isoform of Protein yippee-like OS=Sus scrofa OX=9823 GN=YPEL3 PE=3 SV=1 CANONICAL=A0A4X1U6K5-1" }, "locus": { "chromosome": "3", "start_pos": 18280435, "end_pos": 18278425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068280.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068280.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068347.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068347.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QD97", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QD97" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624297", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624297", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I4H3-1", "protein_name": "Protein yippee-like", "gene_name": "Ypel3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQKYKEGKYIIELNHMIKDNGWD", "length": 119 }, "evidence": [ { "id": "A0A4X1U6K5", "url": "https://omabrowser.org/oma/group/A0A4X1U6K5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P61236-1", "protein_name": "Protein yippee-like 3", "gene_name": "YPEL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQKYKEGKYIIELNHMIKDNGWD", "length": 119 }, "evidence": [ { "id": "A0A4X1U6K5", "url": "https://omabrowser.org/oma/group/A0A4X1U6K5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61237-1", "protein_name": "Protein yippee-like 3", "gene_name": "Ypel3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQKYKEGKYIIELNHMIKDNGWD", "length": 119 }, "evidence": [ { "id": "A0A4X1U6K5", "url": "https://omabrowser.org/oma/group/A0A4X1U6K5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6NWI4-1", "protein_name": "Protein yippee-like 3", "gene_name": "ypel3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVKQTKAKTFQAYLDSCHRRYSCVHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERLLLTGLHAVADIYCENCHTTLGWKYEQAFELSQKYKEGKFIIELSHMIKDNGWD", "length": 119 }, "evidence": [ { "id": "A0A4X1U6K5", "url": "https://omabrowser.org/oma/group/A0A4X1U6K5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9T096-1", "protein_name": "Protein yippee-like At4g27745", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQAIGPRLYSCCNCRNHVGLHDDIISKAFQGRTGRAFLFSHAMNIVVGPKEDRNLLTGLHTVADISCVDCNEPLGWKYERAYETSQKYKEGKFIFEKAKIVKEDW", "length": 106 }, "evidence": [ { "id": "A0A4X1U6K5", "url": "https://omabrowser.org/oma/group/A0A4X1U6K5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6K5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of cellular senescence", "id": "GO:2000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000774", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6K5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U6K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6K5" }, { "id": "PS51792", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51792" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Yippee", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 137, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VD43-1", "uniprot_ac": "A0A4X1VD43", "uniprot_id": "A0A4X1VD43_PIG", "mass": { "chemical_mass": 58534.0, "monoisotopic_mass": 58534.0 }, "refseq": { "ac": "NP_001001628", "name": "CASP8 and FADD-like apoptosis regulator isoform a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" }, "gene_names": [ { "name": "CFLAR", "type": "recommended", "evidence": [ { "id": "A0A4X1VD43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ] }, { "name": "C-FLIP", "type": "synonym", "evidence": [ { "id": "NP_001001628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ] }, { "name": "CFLAR", "type": "synonym", "evidence": [ { "id": "NP_001001628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ] }, { "name": "FLIP", "type": "synonym", "evidence": [ { "id": "NP_001001628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ] } ], "protein_names": [ { "name": "CASP8 and FADD-like apoptosis regulator", "type": "recommended", "evidence": [ { "id": "A0A4X1VD43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43/entry#names_and_taxonomy" } ] }, { "name": "CASP8 and FADD-like apoptosis regulator isoform a", "type": "synonym", "evidence": [ { "id": "NP_001001628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ] }, { "name": "cellular FLICE-like inhibitory protein", "type": "synonym", "evidence": [ { "id": "NP_001001628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ] } ], "function": [ { "annotation": "Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0C4", "url": "https://www.uniprot.org/uniprotkb/A0A287A0C4#function" }, { "database": "UniProtKB", "id": "ARBA00057217", "url": "https://www.uniprot.org/uniprotkb/ARBA00057217#function" }, { "database": "UniProtKB", "id": "A0A287BES4", "url": "https://www.uniprot.org/uniprotkb/A0A287BES4#function" }, { "database": "UniProtKB", "id": "A0A4X1VD53", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD53#function" }, { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43#function" }, { "database": "UniProtKB", "id": "A0A8D0R2E0", "url": "https://www.uniprot.org/uniprotkb/A0A8D0R2E0#function" } ] }, { "annotation": "CFLIPs play important roles in the regulation mechanism of apoptosis in ovarian follicular granulosa cells.", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" }, { "database": "PubMed", "id": "15514461", "url": "https://glygen.org/publication/PubMed/15514461" } ] }, { "annotation": "Cellular-Flice like inhibitory protein (cFLIP) long form, plays an anti-apoptotic role in the granulosa cells of healthy follicles of pig ovaries [cFLIP]", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" }, { "database": "PubMed", "id": "16010689", "url": "https://glygen.org/publication/PubMed/16010689" } ] }, { "annotation": "Intracellular remodeling with overexpression of pig c-FLIP in xenograft cells may decrease the innate cellular responses against xenografts, facilitating long-term xenograft survival.", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" }, { "database": "PubMed", "id": "17175259", "url": "https://glygen.org/publication/PubMed/17175259" } ] }, { "annotation": "Intracellular remodeling with the overexpression of c-FLIP(S/L) in xenograft cells may avoid innate cellular attacks against xenografts and facilitate long-term xenograft survival.", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" }, { "database": "PubMed", "id": "18211505", "url": "https://glygen.org/publication/PubMed/18211505" } ] }, { "annotation": "Overexpression of c-FLIP in xenograft cells may prevent innate cellular attacks against xenografts opening the window of opportunity for long-term xenograft survival.", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" }, { "database": "PubMed", "id": "18374129", "url": "https://glygen.org/publication/PubMed/18374129" } ] }, { "annotation": "Overexpression of the antiapoptotic molecules, pig FLIPs, has the potential for use in protecting graft cells from human natural killer cells in xenografts.", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" }, { "database": "PubMed", "id": "18929860", "url": "https://glygen.org/publication/PubMed/18929860" } ] }, { "annotation": "PcFLIP acts as a survival-promoting factor in granulosa cells and determines whether porcine ovarian follicles survive or undergo atresia.", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" }, { "database": "PubMed", "id": "17594695", "url": "https://glygen.org/publication/PubMed/17594695" } ] }, { "annotation": "We propose that cFLIPS/L acts as a survival factor, and performs an anti-apoptotic function in the porcine corpora lutea. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" }, { "database": "PubMed", "id": "26345752", "url": "https://glygen.org/publication/PubMed/26345752" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CFLAR", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43", "locus": { "chromosome": "15", "start_pos": 104835630, "end_pos": 104781616, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016101", "url": "https://www.ensembl.org/id/ENSSSCG00000016101" } ] } } ], "crossref": [ { "id": "ENSSSCG00000016101", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016101", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00032", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00032", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08337", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "414381", "url": "https://www.ncbi.nlm.nih.gov/gene/414381", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:414381", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414381", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPQHRDY", "url": "https://omabrowser.org/oma/group/MPQHRDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1VD43", "url": "https://www.orthodb.org/?gene=A0A4X1VD43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48169", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48169", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48169:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48169:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00656", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00656", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A0C4", "url": "https://www.uniprot.org/uniprotkb/A0A287A0C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A0C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BES4", "url": "https://www.uniprot.org/uniprotkb/A0A287BES4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BES4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BES4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VD43-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VD53", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VD53-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0R2E0", "url": "https://www.uniprot.org/uniprotkb/A0A8D0R2E0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0R2E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0R2E0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSVPSWASVDWTRFLLLPFLGMTLYRMSAEVIHQVEEALDEDEKEILLFLCRDIAADVVPLNVRDLLDILRERGKLSLVSLAELLYRVRRFDLLKRILKMDRRTVEAQLLRHPHLISDYRVLMMEIGEGLDKSDVSSLIFLMRDHISRSKMAKDKSFLDLVIELEKLNLVAPDHLDLLEKCLRNIHRIDLKTKIQKYKQSAQGAETNYVNALQASLPNLSIKDPSYNLRLQNGRSKEQSLILGHPDFQRDPVKTSIQESGAFLLQHVPEERYKMQSKPLGICLIIDCVGNDTDVLRDTFSSLGYEVQYFLYLKVEQISKILRKVARMPQHQDYDSFVCVLVSRGGSQSVFGVDKTLSGFPLDHIRRMFMADVCPTLLGKPKLFFIQIYVTSEGQLEDSSFLEVDGPSVKSMDSKARQPGTCTVHREADFFWSLCKADVSLLERPSSSSSVYLQCLSQKLGKERKVSLLELHVDLNSKVYDWNSRVSAKERYYVRLQHTLRKKVILSCK", "length": 509, "header": "tr|A0A4X1VD43-1|A0A4X1VD43_PIG Isoform 1 of CASP8 and FADD-like apoptosis regulator OS=Sus scrofa OX=9823 GN=CFLAR PE=3 SV=1 CANONICAL=A0A4X1VD43-1" }, "isoforms": [ { "isoform_ac": "A0A287A0C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43/entry#A0A287A0C4-1", "sequence": { "sequence": "MKSVPSWASVDWTRFLLLPFLGMTLYRMSAEVIHQVEEALDEDEKEILLFLCRDIAADVVPLNVRDLLDILRERGKLSLVSLAELLYRVRRFDLLKRILKMDRRTVEAQLLRHPHLISDYRVLMMEIGEGLDKSDVSSLIFLMRDHISRSKMAKDKSFLDLVIELEKLNLVAPDHLDLLEKCLRNIHRIDLKTKIQKYKQSAQGAETNYVNALQASLPNLSIKDPSYNLRHVPEERYKMQSKPLGICLIIDCVGNDTDVLRDTFSSLGYEVQYFLYLKVEQISKILRKVARMPQHQDYDSFVCVLVSRGGSQSVFGVDKTLSGFPLDHIRRMFMADVCPTLLGKPKLFFIQIYVTSEGQLEDSSFLEVDGPSVKSMDSKARQPGTCTVHREADFFWSLCKADVSLLERPSSSSSVYLQCLSQKLGKERKVSLLELHVDLNSKVYDWNSRVSAKERYYVRLQHTLRKKVILSCK", "length": 473, "header": "tr|A0A287A0C4-1|A0A4X1VD43_PIG Computationally mapped isoform of CASP8 and FADD-like apoptosis regulator OS=Sus scrofa OX=9823 GN=CFLAR PE=3 SV=2 CANONICAL=A0A4X1VD43-1" }, "locus": { "chromosome": "15", "start_pos": 104830462, "end_pos": 104799852, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060342.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060342.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037352.3", "url": "https://www.ensembl.org/id/ENSSSCP00000037352.3" } ] } }, { "isoform_ac": "A0A287BES4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43/entry#A0A287BES4-1", "sequence": { "sequence": "MKSVPSWASVDWTRFLLLPFLGMTLYRMSAEVIHQVEEALDEDEKEILLFLCRDIAADVVPLNVRDLLDILRERGKLSLVSLAELLYRVRRFDLLKRILKMDRRTVEAQLLRHPHLISDYRVLMMEIGEGLDKSDVSSLIFLMRDHISRSKMAKDKSFLDLVIELEKLNLVAPDHLDLLEKCLRNIHRIDLKTKIQKYKQSAQGAETNYVNALQASLPNLSIKDPSYNLRVSLETLIKIVFNNRCFPFQHVPEERYKMQSKPLGICLIIDCVGNDTDVLRDTFSSLGYEVQYFLYLKVEQISKILRKVARMPQHQDYDSFVCVLVSRGGSQSVFGVDKTLSGFPLDHIRRMFMADVCPTLLGKPKLFFIQIYVTSEGQLEDSSFLEVDGPSVKSMDSKARQPGTCTVHREADFFWSLCKADVSLLERPSSSSSVYLQCLSQKLGKERKVSLLELHVDLNSKVYDWNSRVSAKERYYVRLQHTLRKKVILSCK", "length": 492, "header": "tr|A0A287BES4-1|A0A287BES4_PIG Computationally mapped isoform of CASP8 and FADD-like apoptosis regulator OS=Sus scrofa OX=9823 GN=CFLAR PE=3 SV=2 CANONICAL=A0A4X1VD43-1" }, "locus": { "chromosome": "15", "start_pos": 104830462, "end_pos": 104799852, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062262.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062262.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055050.3", "url": "https://www.ensembl.org/id/ENSSSCP00000055050.3" } ] } }, { "isoform_ac": "A0A4X1VD43-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43/entry#A0A4X1VD43-1", "sequence": { "sequence": "MKSVPSWASVDWTRFLLLPFLGMTLYRMSAEVIHQVEEALDEDEKEILLFLCRDIAADVVPLNVRDLLDILRERGKLSLVSLAELLYRVRRFDLLKRILKMDRRTVEAQLLRHPHLISDYRVLMMEIGEGLDKSDVSSLIFLMRDHISRSKMAKDKSFLDLVIELEKLNLVAPDHLDLLEKCLRNIHRIDLKTKIQKYKQSAQGAETNYVNALQASLPNLSIKDPSYNLRLQNGRSKEQSLILGHPDFQRDPVKTSIQESGAFLLQHVPEERYKMQSKPLGICLIIDCVGNDTDVLRDTFSSLGYEVQYFLYLKVEQISKILRKVARMPQHQDYDSFVCVLVSRGGSQSVFGVDKTLSGFPLDHIRRMFMADVCPTLLGKPKLFFIQIYVTSEGQLEDSSFLEVDGPSVKSMDSKARQPGTCTVHREADFFWSLCKADVSLLERPSSSSSVYLQCLSQKLGKERKVSLLELHVDLNSKVYDWNSRVSAKERYYVRLQHTLRKKVILSCK", "length": 509, "header": "tr|A0A4X1VD43-1|A0A4X1VD43_PIG Isoform 1 of CASP8 and FADD-like apoptosis regulator OS=Sus scrofa OX=9823 GN=CFLAR PE=3 SV=1 CANONICAL=A0A4X1VD43-1" }, "locus": { "chromosome": "15", "start_pos": 104830462, "end_pos": 104799852, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017531.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017531.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017059.5", "url": "https://www.ensembl.org/id/ENSSSCP00000017059.5" } ] } }, { "isoform_ac": "A0A4X1VD53-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43/entry#A0A4X1VD53-1", "sequence": { "sequence": "MKSVPSWASVDWTRFLLLPFLGMTLYRMSAEVIHQVEEALDEDEKEILLFLCRDIAADVVPLNVRDLLDILRERGKLSLVSLAELLYRVRRFDLLKRILKMDRRTVEAQLLRHPHLISDYRVLMMEIGEGLDKSDVSSLIFLMRDHISRSKMAKDKSFLDLVIELEKLNLVAPDHLDLLEKCLRNIHRIDLKTKIQKYKQSAQGAETNYVNALQASLPNLSIKDPSYNLRKSLTPGTPR", "length": 239, "header": "tr|A0A4X1VD53-1|A0A4X1VD43_PIG Computationally mapped isoform of CASP8 and FADD-like apoptosis regulator OS=Sus scrofa OX=9823 GN=CFLAR PE=3 SV=1 CANONICAL=A0A4X1VD43-1" }, "locus": { "chromosome": "15", "start_pos": 104830353, "end_pos": 104799852, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036156.4", "url": "https://www.ensembl.org/id/ENSSSCT00000036156.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028277.2", "url": "https://www.ensembl.org/id/ENSSSCP00000028277.2" } ] } }, { "isoform_ac": "A0A8D0R2E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43/entry#A0A8D0R2E0-1", "sequence": { "sequence": "MKSVPSWASVDWTRFLLLPFLGMTLYRMSAEVIHQVEEALDEDEKEILLFLCRDIAADVVPLNVRDLLDILRERGKLSLVSLAELLYRVRRFDLLKRILKMDRRTVEAQLLRHPHLISDYRVLMMEIGEGLDKSDVSSLIFLMRDHISRSKMAKDKSFLDLVIELEKLNLVAPDHLDLLEKCLRNIHRIDLKTKIQKYKQSAQGAETNYVNALQASLPNLSIKDPSYNLRVSLEQVAGSLTH", "length": 242, "header": "tr|A0A8D0R2E0-1|A0A4X1VD43_PIG Computationally mapped isoform of CASP8 and FADD-like apoptosis regulator OS=Sus scrofa OX=9823 GN=CFLAR PE=3 SV=1 CANONICAL=A0A4X1VD43-1" }, "locus": { "chromosome": "15", "start_pos": 104807348, "end_pos": 104799852, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053079.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053079.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037053.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037053.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Porcine (Sus scrofa) cellular FLICE-like inhibitory protein (cFLIP): molecular cloning and comparison with the human and murine cFLIP.", "journal": "The Journal of reproduction and development", "date": "2004-10", "authors": "Goto Yasufumi, Matsuda-Minehata Fuko, Inoue Naoko, Matsui Toshikatsu, Maeda Akihisa, Manabe Noboru", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ], "reference": [ { "type": "PubMed", "id": "15514461", "url": "https://glygen.org/publication/PubMed/15514461" } ] }, { "title": "Changes in expression of anti-apoptotic protein, cFLIP, in granulosa cells during follicular atresia in porcine ovaries.", "journal": "Molecular reproduction and development", "date": "2005-10", "authors": "Matsuda-Minehata Fuko, Goto Yasufumi, Inoue Naoko, Manabe Noboru", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ], "reference": [ { "type": "PubMed", "id": "16010689", "url": "https://glygen.org/publication/PubMed/16010689" } ] }, { "title": "A novel strategy for preventing human CD8+ cytotoxic T lymphocyte-mediated cytotoxicity against pig endothelial cells by overexpression of pig cellular FLICE-like inhibitory protein (c-FLIP) gene.", "journal": "Transplantation proceedings", "date": "2006-12", "authors": "Tanemura M, Saga A, Kawamoto K, Matsuda-Minehata F, Manabe N, Deguchi T, Nishida T, Sawa Y, Ito T", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ], "reference": [ { "type": "PubMed", "id": "17175259", "url": "https://glygen.org/publication/PubMed/17175259" } ] }, { "title": "Anti-apoptotic activity of porcine cFLIP in ovarian granulosa cell lines.", "journal": "Molecular reproduction and development", "date": "2007-09", "authors": "Matsuda-Minehata Fuko, Goto Yasufumi, Inoue Naoko, Sakamaki Kazuhiro, Chedrese P Jorge, Manabe Noboru", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ], "reference": [ { "type": "PubMed", "id": "17594695", "url": "https://glygen.org/publication/PubMed/17594695" } ] }, { "title": "In vitro and in vivo prevention of human CD8+ CTL-mediated xenocytotoxicity by pig c-FLIP expression in porcine endothelial cells.", "journal": "American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons", "date": "2008-02", "authors": "Tanemura M, Saga A, Kawamoto K, Deguchi T, Machida T, Nishida T, Sawa Y, Ito T", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ], "reference": [ { "type": "PubMed", "id": "18211505", "url": "https://glygen.org/publication/PubMed/18211505" } ] }, { "title": "Pig cellular FLICE-like inhibitory protein (c-FLIP) overexpression in pig xenograft cells induces resistance to human CD8+ cytotoxic T lymphocyte-mediated xenocytotoxicity.", "journal": "Transplantation proceedings", "date": "2008-03", "authors": "Tanemura M, Saga A, Kawamoto K, Manabe N, Machida T, Deguchi T, Sawa Y, Nishida T, Ito T", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ], "reference": [ { "type": "PubMed", "id": "18374129", "url": "https://glygen.org/publication/PubMed/18374129" } ] }, { "title": "Cloning and in vitro antiapoptotic effects of pig FLIPs.", "journal": "Transplantation proceedings", "date": "2008-10", "authors": "Xu H, Firdawes S, Yamamoto A, Matsunami K, Ishimaru A, Kondo A, Fukuzawa M, Miyagawa S", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ], "reference": [ { "type": "PubMed", "id": "18929860", "url": "https://glygen.org/publication/PubMed/18929860" } ] }, { "title": "Expression and localization of cFLIP anti-apoptotic protein in the porcine corpus luteum and corpora albicans during the estrous cycle and pregnancy.", "journal": "Genetics and molecular research : GMR", "date": "2015-07-27", "authors": "Jin H Z, Shi W S, Tian Y, Liu Y, Jin Y, Manabe N", "evidence": [ { "database": "RefSeq", "id": "NP_001001628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001628" } ], "reference": [ { "type": "PubMed", "id": "26345752", "url": "https://glygen.org/publication/PubMed/26345752" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD53", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD53" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:414381", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414381", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MFY0-1", "protein_name": "CASP8 and FADD-like apoptosis regulator", "gene_name": "CFLAR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKSVASWPSIDWTRLFFLPFLGMTLYRMSAEVIHQVEEALDEEEKDTLLFLCRDVAADVVPLNVRDLLDILRERGKLSSVSLAELLYRVRRFDLLKRVLNMDTPTVEALLRKHPHLISDYRVLMMEIGEDLDKSDVSSLMFLMRDYTGRSKIAKDKSFLDLVVELEKLNLVAPDQLNLLEESLRNINRIDLKTKIQKYKQSAQGAETNYVNARQASLPNLSVKDPSYNLRLQNGRSKEQRLMMGPPDIQREPVKRPIQESGAFLPQHIVEERYKMQSKPLGICLIIDCIGNDTDILRDTFTSLGYEVKHFLYLTVKDITNILRQVAQMPQHQDSDSFACILVSRGGSQSVFGVDQTHSGVPLDHIRRMFMADTCPSLSGKPKLFFIQSYVKSEGQLEDSSFLEVDGPSVKSADSKARQPGPYQDLIHREADFFWSLCKADVSLLEGPSSSPSLYLKCLSQKLWKERKHSLLELHTELNRLVYDWNSKVSAKERYYVWLQHTLRKNLFLSHK", "length": 511 }, "evidence": [ { "id": "A0A4X1VD43", "url": "https://omabrowser.org/oma/group/A0A4X1VD43/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "C0H5Y5-1", "protein_name": "CASP8 and FADD-like apoptosis regulator", "gene_name": "Cflar", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALSTVSAEVIHQVEESLDEDEKEMMLFLCRDVTENLAPPNVRDLLDCLSERGQLSFAALAELLYRVRRFDLLKRILKTDKAAVEDHLCRSPHLVSDYRVLLMEIGENLNQSDVSSLIFLTKDYTGRGKVAKDKSFLDLVIELEKLNLIGSDQLNLLEKCLKSIHRIDLKTKIQKYTQSSQEARSNMNALQASLPKLSIKEHLYNSRLQNGRSKEPRFVEHHGIQRKPVKTSIQESGIFLPPHIHEESYRMQSKPLGICLIIDCIGNDTEYLRETFTSLGYRVQPFLFPSSHEITQIVRRFSNMTQHQDYDSFVCVLVSRGGSQSMMGVDQVYSGFSLENVKDMFKGDMCPSLRGKPKLFFIQNYEALEDNSLEVDGPAIKNVNSRHLHPRHCTTHPDADIFWSLCTADVSRLEQPSSSLSVYLQKLSQLLEQGRKRSLVDLHVELMDKVYAWNSNVPSKEKYYLSLQHTLRKKLILSHT", "length": 480 }, "evidence": [ { "id": "A0A4X1VD43", "url": "https://omabrowser.org/oma/group/A0A4X1VD43/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C4U6-1", "protein_name": "CASP8 and FADD-like apoptosis regulator", "gene_name": "CFLAR", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTKCQVPAVLIHQIEEELDKEEVDMMVFLCRDLAPDLATAGLRELLGALNERDKLSLLGLSELLYRVKRFDLLRRILKTEKTTVEANLTRNPRLVPDYRVLMVEISENLEKDEVSSLVFLLRDFAPRMKMAKDKSFLRLIIELEKLNLVAPNQLDLIENCFRNIHRIDLIKKIEKYKQEAFISSVHSQPVYVNALQASLPNLSLIDPPYNSGNMNKEKSQNGEIFFQEEPVHVSIQESGPASHKFPQVYRMQSQPLGVCLIIDCVGYDTDMLEETFRGLDYEVHCHKHLNVTTMNETLIKVARLQKHRSCDSFICILVSRGNAQSIFCTDTISTGFPLEQIKKYFMADSCPELRGKPKLFFIQSYIVPEDEQEYTSLEIDGNDKKIISRAKTPLKDTIPQVADIFWSHSKVDVSTLEKSPRPSSYYLRCLAELLRNPHKRKLSILDIHTELNRRVYEWNKTTDPSQQYSLLLQHTLRKTLILSPVNCYWKGHV", "length": 493 }, "evidence": [ { "id": "A0A4X1VD43", "url": "https://omabrowser.org/oma/group/A0A4X1VD43/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O15519-1", "protein_name": "CASP8 and FADD-like apoptosis regulator", "gene_name": "CFLAR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLYRVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT", "length": 480 }, "evidence": [ { "id": "A0A4X1VD43", "url": "https://omabrowser.org/oma/group/A0A4X1VD43/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35732-1", "protein_name": "CASP8 and FADD-like apoptosis regulator", "gene_name": "Cflar", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQSPVSAEVIHQVEECLDEDEKEMMLFLCRDVTENLAAPNVRDLLDSLSERGQLSFATLAELLYRVRRFDLLKRILKTDKATVEDHLRRNPHLVSDYRVLLMEIGESLDQNDVSSLVFLTRDYTGRGKIAKDKSFLDLVIELEKLNLIASDQLNLLEKCLKNIHRIDLNTKIQKYTQSSQGARSNMNTLQASLPKLSIKYNSRLQNGRSKEPRFVEYRDSQRTLVKTSIQESGAFLPPHIREETYRMQSKPLGICLIIDCIGNDTKYLQETFTSLGYHIQLFLFPKSHDITQIVRRYASMAQHQDYDSFACVLVSLGGSQSMMGRDQVHSGFSLDHVKNMFTGDTCPSLRGKPKLFFIQNYESLGSQLEDSSLEVDGPSIKNVDSKPLQPRHCTTHPEADIFWSLCTADVSHLEKPSSSSSVYLQKLSQQLKQGRRRPLVDLHVELMDKVYAWNSGVSSKEKYSLSLQHTLRKKLILAPT", "length": 481 }, "evidence": [ { "id": "A0A4X1VD43", "url": "https://omabrowser.org/oma/group/A0A4X1VD43/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "pmid": "" }, { "name": "ripoptosome", "id": "GO:0097342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097342", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "pmid": "" }, { "name": "death-inducing signaling complex", "id": "GO:0031264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031264", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001237", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "pmid": "" }, { "name": "regulation of necroptotic process", "id": "GO:0060544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060544", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "pmid": "" }, { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VD43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1VD43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" }, { "id": "PS50208", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50208" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Caspase family p20", "eco_id": "ECO_0000259", "start_pos": 292, "end_pos": 387, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1VD43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VD43" }, { "id": "PS50168", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50168" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DED", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 100, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 219, "end_pos": 221 }, { "start_pos": 291, "end_pos": 293 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VI83-1", "uniprot_ac": "A0A4X1VI83", "uniprot_id": "A0A4X1VI83_PIG", "mass": { "chemical_mass": 79591.0, "monoisotopic_mass": 79591.0 }, "refseq": { "ac": "XP_020945650", "name": "ankyrin repeat domain-containing protein 6 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945650" }, "gene_names": [ { "name": "ANKRD6", "type": "recommended", "evidence": [ { "id": "A0A4X1VI83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83" } ] }, { "name": "ANKRD6", "type": "synonym", "evidence": [ { "id": "XP_020945650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945650" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 6", "type": "recommended", "evidence": [ { "id": "A0A4X1VI83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83/entry#names_and_taxonomy" } ] }, { "name": "Diversin", "type": "synonym", "evidence": [ { "id": "A0A4X1VI83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 6 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020945650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945650" } ] } ], "function": [ { "annotation": "Recruits CKI-epsilon to the beta-catenin degradation complex that consists of AXN1 or AXN2 and GSK3-beta and allows efficient phosphorylation of beta-catenin, thereby inhibiting beta-catenin/Tcf signals.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VI83", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83#function" }, { "database": "UniProtKB", "id": "ARBA00056242", "url": "https://www.uniprot.org/uniprotkb/ARBA00056242#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VI83", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ANKRD6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83", "locus": { "chromosome": "1", "start_pos": 57645957, "end_pos": 57438000, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004322", "url": "https://www.ensembl.org/id/ENSSSCG00000004322" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004322", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004322", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "102167335", "url": "https://www.ncbi.nlm.nih.gov/gene/102167335", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MKTEIHA", "url": "https://omabrowser.org/oma/group/MKTEIHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173:SF74", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173:SF74", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198:SF185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198:SF185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24203:SF84", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24203:SF84", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020945650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945650", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A1T9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AIS9", "url": "https://www.uniprot.org/uniprotkb/A0A287AIS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AIS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AIS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VE87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VE87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VE87-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VE87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VI83", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VI83-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1IQ94", "url": "https://www.uniprot.org/uniprotkb/A0A8D1IQ94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1IQ94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1IQ94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1UX15", "url": "https://www.uniprot.org/uniprotkb/A0A8D1UX15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1UX15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1UX15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQQDAVAALSERLLIAAYKGQAENVVQLINKGAKVAVTKHGRTALHLAANKGHLSVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEVIAALIQEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHAQSTRVLLLGGSRADLKNNAGDTCLHVAARYNHLSIIKLLLSAFCSVHEKNQAGDTALHIAAALNHKKVVKILLEAGADGTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKGSVSAGDTHSSEQAAPRKEEAKEDCLSASPEPRAKDCRQRKSRPKVSAFSDPTPPADQQPGQQKNTHTHSHPKKRPRRRCSPPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELVSVQDKMNTKLGHMESKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDSEKHEGEKRQMSLVDELKTWCMLKIQNLELKLSGDSRASRTKSTPSTCESSTGVDQSVVTAVAAVASDSSPQVVRPKEKAPSSTATHRPQQELSSSDHTGSRLRNVKVQTASLPLKEAAKCDSQAGPCVDRGTQTKKSGKSGQMRHRGQQPAPSAACGQPPPAAGGEQTAPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQASQKAQQDKATLEEHIKSLEEELAKLRTKVQKEN", "length": 727, "header": "tr|A0A4X1VI83-1|A0A4X1VI83_PIG Isoform 1 of Ankyrin repeat domain-containing protein 6 OS=Sus scrofa OX=9823 GN=ANKRD6 PE=4 SV=1 CANONICAL=A0A4X1VI83-1" }, "isoforms": [ { "isoform_ac": "A0A287A1T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83/entry#A0A287A1T9-1", "sequence": { "sequence": "MSQQDAVAALSERLLIAAYKGQAENVVQLINKGAKVAVTKHGRTALHLAANKGHLSVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEVIAALIQEGCALDRQDKAGNTALHLACQNSHAQSTRVLLLGGSRADLKNNAGDTCLHVAARYNHLSIIKLLLSAFCSVHEKNQAGDTALHIAAALNHKKVVKILLEAGADGTIVNNAGQTPLETARYHNNPEVALLLTKAPQGSVSAGDTHSSEQAAPRKEEAKEDCLSASPEPRAKDCRQRKSRPKVSAFSDPTPPADQQPGQQKNTHTHSHPKKRPRRRCSPPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELVSVQDKMNTKLGHMESKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDSEKHEGEKRQMSLVDELKTWCMLKIQNLELKLSGDSRASRTKSTPSTCESSTGVDQSVVTAVAAVASDSSPQVVRPKEKAPSSTATHRPQQELSSSDHTGSRLRNVKVQTASLPLKEAAKCDSQAGPCVDRGTQTKKSGKSGQMRHRGQQPAPSAACGQPPPAAGGEQTAPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQASQKAQQDKATLEEHIKSLEEELAKLRTKVQKEN", "length": 659, "header": "tr|A0A287A1T9-1|A0A4X1VI83_PIG Computationally mapped isoform of Ankyrin repeat domain-containing protein 6 OS=Sus scrofa OX=9823 GN=ANKRD6 PE=4 SV=1 CANONICAL=A0A4X1VI83-1" }, "locus": { "chromosome": "1", "start_pos": 57644228, "end_pos": 57580603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063190.1", "url": "https://www.ensembl.org/id/ENSSSCT00000063190.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037893.1", "url": "https://www.ensembl.org/id/ENSSSCP00000037893.1" } ] } }, { "isoform_ac": "A0A287AIS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83/entry#A0A287AIS9-1", "sequence": { "sequence": "MSRMMGIRPPCTGPRWWGTPRSLRHSSRRAVLWTGRTRMGTQPCTKHPGMVSASQPSYSLKQEPMCLPRTRLGTRLCTWPARTAMPRAHASSCWAGPVPTSKTTQATPVCTLPHVIITCPSLSSSSAGDTALHIAAALNHKKVVKILLEAGADGTIVNNAGQTPLETARYHNNPEVALLLTKAPQGSVSAGDTHSSEQAAPRKEEAKEDCLSASPEPRAKDCRQRKSRPKVSAFSDPTPPADQQPGQQKNTHTHSHPKKRPRRRCSPPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELVSVQDKMNTKLGHMESKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDSEKHEGEKRQMSLVDELKTWCMLKIQNLELKLSGDSRASRTKSTPSTCESSTGVDQSVVTAVAAVASDSSPQVVRPKEKAPSSTATHRPQQELSSSDHTGSRLRNVKVQTASLPLKEAAKCDSQAGPCVDRGTQTKKSGKSGQMRHRGQQPAPSAACGQPPPAAGGEQTAPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQASQKAQQDKATLEEHIKSLEEELAKLRTKVQKEN", "length": 613, "header": "tr|A0A287AIS9-1|A0A4X1VI83_PIG Computationally mapped isoform of Ankyrin repeat domain-containing protein 6 OS=Sus scrofa OX=9823 GN=ANKRD6 PE=4 SV=2 CANONICAL=A0A4X1VI83-1" }, "locus": { "chromosome": "1", "start_pos": 57644228, "end_pos": 57607508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055894.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055894.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043799.2", "url": "https://www.ensembl.org/id/ENSSSCP00000043799.2" } ] } }, { "isoform_ac": "A0A4X1VE87-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83/entry#A0A4X1VE87-1", "sequence": { "sequence": "MSQQDAVAALSERLLIAAYKGQAENVVQLINKGAKVAVTKHGRTALHLAANKGHLSVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEVIAALIQEGCALDRQDKAGNTALHLACQNSHAQSTRVLLLGGSRADLKNNAGDTCLHVAARYNHLSIIKLLLSAFCSVHEKNQAGDTALHIAAALNHKKVVKILLEAGADGTIVNNVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKGSVSAGDTHSSEQAAPRKEEAKEDCLSASPEPRAKDCRQRKSRPKVSAFSDPTPPADQQPGQQKNTHTHSHPKKRPRRRCSPPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELVSVQDKMNTKLGHMESKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDSEKHEGEKRQMSLVDELKTWCMLKIQNLELKLSGDSRASRTKSTPSTCVDQSVVTAVAAVASDSSPQVVRPKEKAPSSTATHRPQQELSSSDHTGSRLRNVKVQTASLPLKEAAKCDSQAGPCVDRGTQTKKSGKSGQMRHRGQQPAPSAACGQPPPAAGGEQTAPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQASQKAQQDKATLEEHIKSLEEELAKLRTKVQKEN", "length": 663, "header": "tr|A0A4X1VE87-1|A0A4X1VI83_PIG Computationally mapped isoform of Ankyrin repeat domain-containing protein 6 OS=Sus scrofa OX=9823 GN=ANKRD6 PE=4 SV=1 CANONICAL=A0A4X1VI83-1" }, "locus": { "chromosome": "1", "start_pos": 57644228, "end_pos": 57580603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004778.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004778.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004667.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004667.4" } ] } }, { "isoform_ac": "A0A4X1VI83-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83/entry#A0A4X1VI83-1", "sequence": { "sequence": "MSQQDAVAALSERLLIAAYKGQAENVVQLINKGAKVAVTKHGRTALHLAANKGHLSVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEVIAALIQEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHAQSTRVLLLGGSRADLKNNAGDTCLHVAARYNHLSIIKLLLSAFCSVHEKNQAGDTALHIAAALNHKKVVKILLEAGADGTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKGSVSAGDTHSSEQAAPRKEEAKEDCLSASPEPRAKDCRQRKSRPKVSAFSDPTPPADQQPGQQKNTHTHSHPKKRPRRRCSPPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELVSVQDKMNTKLGHMESKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDSEKHEGEKRQMSLVDELKTWCMLKIQNLELKLSGDSRASRTKSTPSTCESSTGVDQSVVTAVAAVASDSSPQVVRPKEKAPSSTATHRPQQELSSSDHTGSRLRNVKVQTASLPLKEAAKCDSQAGPCVDRGTQTKKSGKSGQMRHRGQQPAPSAACGQPPPAAGGEQTAPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQASQKAQQDKATLEEHIKSLEEELAKLRTKVQKEN", "length": 727, "header": "tr|A0A4X1VI83-1|A0A4X1VI83_PIG Isoform 1 of Ankyrin repeat domain-containing protein 6 OS=Sus scrofa OX=9823 GN=ANKRD6 PE=4 SV=1 CANONICAL=A0A4X1VI83-1" }, "locus": { "chromosome": "1", "start_pos": 57644228, "end_pos": 57580603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043370.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043370.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043818.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043818.1" } ] } }, { "isoform_ac": "A0A8D1IQ94-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83/entry#A0A8D1IQ94-1", "sequence": { "sequence": "KPRRKKKIRKTREERLGRTLEDGDQTALHRATVVGNTEVIAALIQEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHAQSTRVLLLGGSRADLKNNAGDTCLHVAARYNHLSIIKLLLSAFCSVHEKNQAGDTALHIAAALNHKKVVKILLEAGADGTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKGSVSAGDTHSSEQAAPRKEEAKEDCLSASPEPRAKDCRQRKSRPKVSAFSDPTPPADQQPGQQKNTHTHSHPKKRPRRRCSPPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELVSVQDKMNTKLGHMESKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDSEKHEGEKRQMSLVDELKTWCMLKIQNLELKLSGDSRASRTKSTPSTCESSTGVDQSVVTAVAAVASDSSPQVVRPKEKAPSSTATHRPQQELSSSDHTGSRLRNVKVQTASLPLKEAAKCDSQAGPCVDRGTQTKKSGKSGQMRHRGQQPAPSAACGQPPPAAGGEQTAPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQASQKAQQDKATLEEHIKSLEEELAKLRTKVQKEN", "length": 676, "header": "tr|A0A8D1IQ94-1|A0A4X1VI83_PIG Computationally mapped isoform of Ankyrin repeat domain-containing protein 6 OS=Sus scrofa OX=9823 GN=ANKRD6 PE=4 SV=1 CANONICAL=A0A4X1VI83-1" }, "locus": { "chromosome": "1", "start_pos": 57644228, "end_pos": 57610095, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056510.2", "url": "https://www.ensembl.org/id/ENSSSCT00000056510.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051099.2", "url": "https://www.ensembl.org/id/ENSSSCP00000051099.2" } ] } }, { "isoform_ac": "A0A8D1UX15-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83/entry#A0A8D1UX15-1", "sequence": { "sequence": "MSQQDAVAALSERLLIAAYKGQAENVVQLINKGAKVAVTKHGRTALHLAANKGHLSVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEVIAALIQEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHAQSTRVLLLGGSRADLKNNAGDTCLHVAARYNHLSIIKLLLSAFCSVHEKNQAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKGSVSAGDTHSSEQAAPRKEEAKEDCLSASPEPRAKDCRQRKSRPKVSAFSDPTPPADQQPGQQKNTHTHSHPKKRPRRRCSPPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELVSVQDKMNTKLGHMESKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDSEKHEGEKRQMSLVDELKTWCMLKIQNLELKLSGDSRASRTKSTPSTCESSTGVDQSVVTAVAAVASDSSPQVVRPKEKAPSSTATHRPQQELSSSDHTGSRLRNVKVQTASLPLKEAAKCDSQAGPCVDRGTQTKKSGKSGQMRHRGQQPAPSAACGQPPPAAGGEQTAPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQASQKAQQDKATLEEHIKSLEEELAKLRTKVQKEN", "length": 694, "header": "tr|A0A8D1UX15-1|A0A4X1VI83_PIG Computationally mapped isoform of Ankyrin repeat domain-containing protein 6 OS=Sus scrofa OX=9823 GN=ANKRD6 PE=4 SV=1 CANONICAL=A0A4X1VI83-1" }, "locus": { "chromosome": "1", "start_pos": 57644228, "end_pos": 57580603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039423.2", "url": "https://www.ensembl.org/id/ENSSSCT00000039423.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033772.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033772.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VE87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VE87" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M8A1-1", "protein_name": "Ankyrin repeat domain-containing protein 6", "gene_name": "ANKRD6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQQDAVAALSERLLIAAYKGQTENVVQLINKGAKVAVTKHGRTPLHLAANKGHLSVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEVIAALIQEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHAQSTRVLLLGGSRADLKNNAGDTCLHVAARYNHLSIIKLLLSAFCSVHEKNQAGDTALHIAAALNHKKVVKILLEAGADGTIVNNAGRTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKGSVSAGDTHSSEQAAPRKEEAREDVLSASPEPRAKDSRQRKSRPKVSAFSDPTPPADQQPGQQKNVHAHSHPKKRPRHRCSPPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELVSVQDKMNVKLGHMENKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDSEKHEGEKRQMSLVDELKTWCMLKIQNLELKLSGDSRASRTKSTPSTCVDQSVVTAGPVAASDSSPQVVRPKEKALSSTATHRLQQQELSSSDCTGSRLRNVKVQTASLPLKETARCDPQAGPCVDRGTQTKKSGKSGQTRHRGQQPAVSTAGGQPLPSAAGGEQTAPHVRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQASQKAQQDKATLEEHIKSLEEELAKLRTKVQKEN", "length": 724 }, "evidence": [ { "id": "A0A4X1VI83", "url": "https://omabrowser.org/oma/group/A0A4X1VI83/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B5DEH9-1", "protein_name": "Ankyrin repeat domain-containing protein 6", "gene_name": "Ankrd6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQQDAVAALSERLLIAAYKGQTENVVQLINKGAKVAVTKHGRTPLHLAANKGHLSVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEILTALIREGCALDRQDKDGNTALHEAAWHGFSQSAKLLVKAGANVLARNKAGNTALHLACQNSHSQSTRVLLLGGSRADLKNNAGDTCLHVAARYNHLSVVRLLLSAFCSVHEKNQAGDTALHVAAALNHKKVVKILLEAGADTTLVNNAGQTPLETARYHDNPEVALLLTKAPQILRFSRGRSLRKRRERLKEERRAQSVPRDEVAQSKGSVSAGDTPSSEQAVPEKEEARRDCPPASQEPRKDERRRKSRPEVSALSDPTPAADQQPGHQKNLHGHHHQKKKSRHRCWSPPPPHGFRAYQLYTLYRGEDGKVMQAPIKGCRCEPLINKLENQLEAAVEELRAELGTVQDKVNTKLGHMESKSQHQMCVLDKLMVERLSAERTECLNRLQQHAAAEKQEGEKRQMSLVDELKSWCMLKIQNLELRLSGESRTFRAKSTPSPSDSSPAVDQPVVAAGPGAASDSSSQVVRPKDKALNATAVPRHQQELLPSDCTGSGLRKVKAPAASRLGDQQTGSCVNRGTQTKKSARGGQTKHRGQQPTASSPSGQQPSAASSDARDASQALELTQYFFEAVSAQMEKWYERKIEEARSQASQKAQQDEATLKEHIRSLEEEVAKLRTKMHK", "length": 713 }, "evidence": [ { "id": "A0A4X1VI83", "url": "https://omabrowser.org/oma/group/A0A4X1VI83/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q69ZU8-1", "protein_name": "Ankyrin repeat domain-containing protein 6", "gene_name": "Ankrd6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQQDAVAALSERLLIAAYKGQTENVVQLINKGAKVAVTKHGRTPLHLAANKGHLSVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEILTALIREGCALDRQDKDGNTALHEAAWHGFSQSAKLLVKAGANVLARNKAGNTALHLACQNSHSQSTRILLLGGSRADLKNNAGDTCLHVAARYNHLSVVRLLLNAFCSVHEKNQAGDTALHVAAALNHKKVVKVLLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQILRFSRGRSLRKRRERLKEERRAQSVPRDEVAQSKGSVSAGDTPSSEQAVPQKEEARRDCPPASQEPRKDERRRKSRPEVSALSDPTPAADQQPGHQKNLHSHHHPKKKSRHRCWSPPPPHGFRAYQLYTLYRGEDGKVMQAPIKGCRCEPLINKLENQLEATVEEIRAELGSVQDKVNAKLGQMESKTQHQMCVLDKLMVERLSAERTECMNRLQQHAAAEKQEGEKRQMSLVDELKAWCMLKIQSLELRLSGESRTFRAKSTPPPSDSTPAVDQPVVAAGPGAASDSSSQVVRPKDKALNASAAHSHQQELPPSDCTGSGLRKIKAPGASRCDQQTGSCVNRGTQTKKSGRSGQTKHRGQQPTASSPSGQQPSAASSDVRDASQALELTQYFFEAVSAQMEKWYERKIEEARSQASQKAQQDEATLKEHIRSLEEELARLRTKVQK", "length": 712 }, "evidence": [ { "id": "A0A4X1VI83", "url": "https://omabrowser.org/oma/group/A0A4X1VI83/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VI83", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VI83", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of Wnt signaling pathway", "id": "GO:0030111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030111", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VI83", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VI83", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VQD7-1", "uniprot_ac": "A0A4X1VQD7", "uniprot_id": "A0A4X1VQD7_PIG", "mass": { "chemical_mass": 69218.0, "monoisotopic_mass": 69218.0 }, "refseq": { "ac": "XP_020930311", "name": "set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020930311" }, "gene_names": [ { "name": "ASH2L", "type": "recommended", "evidence": [ { "id": "A0A4X1VQD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ] }, { "name": "ASH2L", "type": "synonym", "evidence": [ { "id": "XP_020930311", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020930311" } ] } ], "protein_names": [ { "name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "type": "recommended", "evidence": [ { "id": "A0A4X1VQD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7/entry#names_and_taxonomy" } ] }, { "name": "ASH2-like protein", "type": "synonym", "evidence": [ { "id": "A0A4X1VQD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7/entry#names_and_taxonomy" } ] }, { "name": "set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020930311", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020930311" } ] } ], "function": [ { "annotation": "Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A6Q3", "url": "https://www.uniprot.org/uniprotkb/A0A287A6Q3#function" }, { "database": "UniProtKB", "id": "ARBA00056054", "url": "https://www.uniprot.org/uniprotkb/ARBA00056054#function" }, { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ASH2L", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7", "locus": { "chromosome": "15", "start_pos": 48386425, "end_pos": 48417547, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021898", "url": "https://www.ensembl.org/id/ENSSSCG00000021898" } ] } } ], "crossref": [ { "id": "cd12872", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12872", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15583", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15583", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100627423", "url": "https://www.ncbi.nlm.nih.gov/gene/100627423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10598", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10598", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10598:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10598:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-201722", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3214841", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214841", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8936459", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8936459", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9772755", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9772755", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9909649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9909649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020930311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020930311", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A6Q3", "url": "https://www.uniprot.org/uniprotkb/A0A287A6Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A6Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A6Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VQD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGTGPGPGVGAGTGPTAAVNATPAEEGETKPVAAVAAAPAGEGTSVTPAAEPVSGEAESGDANSVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSTVSTSGNLNGGASFGGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLAYRPMSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP", "length": 634, "header": "tr|A0A4X1VQD7-1|A0A4X1VQD7_PIG Isoform 1 of Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Sus scrofa OX=9823 GN=ASH2L PE=1 SV=1 CANONICAL=A0A4X1VQD7-1" }, "isoforms": [ { "isoform_ac": "A0A287A6Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7/entry#A0A287A6Q3-1", "sequence": { "sequence": "MAAAGTGPGPGVGAGTGPTAAVNATPAEEGETKPVAAVAAAPAGEGTSVTPAAEPVSGEAESGDANSVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSTVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEVSINFGPCFKYPPKDLAYRPMSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP", "length": 595, "header": "tr|A0A287A6Q3-1|A0A4X1VQD7_PIG Computationally mapped isoform of Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Sus scrofa OX=9823 GN=ASH2L PE=1 SV=3 CANONICAL=A0A4X1VQD7-1" }, "locus": { "chromosome": "15", "start_pos": 48417509, "end_pos": 48387611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048058.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048058.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039488.3", "url": "https://www.ensembl.org/id/ENSSSCP00000039488.3" } ] } }, { "isoform_ac": "A0A4X1VQD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7/entry#A0A4X1VQD7-1", "sequence": { "sequence": "MAAAGTGPGPGVGAGTGPTAAVNATPAEEGETKPVAAVAAAPAGEGTSVTPAAEPVSGEAESGDANSVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSTVSTSGNLNGGASFGGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLAYRPMSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP", "length": 634, "header": "tr|A0A4X1VQD7-1|A0A4X1VQD7_PIG Isoform 1 of Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Sus scrofa OX=9823 GN=ASH2L PE=1 SV=1 CANONICAL=A0A4X1VQD7-1" }, "locus": { "chromosome": "15", "start_pos": 48417509, "end_pos": 48387611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023044.4", "url": "https://www.ensembl.org/id/ENSSSCT00000023044.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019990.4", "url": "https://www.ensembl.org/id/ENSSSCP00000019990.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 50, "start_aa": "Thr", "end_pos": 50, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr50", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A6Q3", "url": "https://www.uniprot.org/uniprotkb/A0A287A6Q3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-201722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201722", "resource": "Reactome", "description": "Formation of the beta-catenin:TCF transactivating complex" }, { "id": "R-SSC-3214841", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214841", "resource": "Reactome", "description": "PKMTs methylate histone lysines" }, { "id": "R-SSC-8936459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8936459", "resource": "Reactome", "description": "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" }, { "id": "R-SSC-9772755", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9772755", "resource": "Reactome", "description": "Formation of WDR5-containing histone-modifying complexes" }, { "id": "R-SSC-9909649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9909649", "resource": "Reactome", "description": "Regulation of PD-L1(CD274) transcription" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "positive regulation of macromolecule biosynthetic process", "id": "GO:0010557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010557", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "response to estrogen", "id": "GO:0043627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043627", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "MLL1 complex", "id": "GO:0071339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071339", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" }, { "name": "MLL3/4 complex", "id": "GO:0044666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044666", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VQD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1VQD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VQD7" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 366, "end_pos": 589, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 19, 25, 50 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 175, "end_pos": 177 }, { "start_pos": 23, "end_pos": 25 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1V7A7-1", "uniprot_ac": "A0A4X1V7A7", "uniprot_id": "A0A4X1V7A7_PIG", "mass": { "chemical_mass": 48678.0, "monoisotopic_mass": 48678.0 }, "refseq": { "ac": "XP_003357916", "name": "F-box/LRR-repeat protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357916" }, "gene_names": [ { "name": "FBXL3", "type": "recommended", "evidence": [ { "id": "A0A4X1V7A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ] }, { "name": "FBXL3", "type": "synonym", "evidence": [ { "id": "XP_003357916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357916" } ] } ], "protein_names": [ { "name": "F-box/LRR-repeat protein 21", "type": "recommended", "evidence": [ { "id": "A0A4X1V7A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7/entry#names_and_taxonomy" } ] }, { "name": "F-box and leucine-rich repeat protein 21", "type": "synonym", "evidence": [ { "id": "A0A4X1V7A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7/entry#names_and_taxonomy" } ] }, { "name": "F-box/LRR-repeat protein 3", "type": "synonym", "evidence": [ { "id": "XP_003357916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357916" } ] } ], "function": [ { "annotation": "Substrate-recognition component of the SCF(FBXL21) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL21) complex mainly acts in the cytosol and mediates ubiquitination of CRY proteins (CRY1 and CRY2), leading to CRY proteins stabilization. The SCF(FBXL21) complex counteracts the activity of the SCF(FBXL3) complex and protects CRY proteins from degradation. Involved in the hypothalamic suprachiasmatic nucleus (SCN) clock regulating temporal organization of the daily activities.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A8U4", "url": "https://www.uniprot.org/uniprotkb/A0A287A8U4#function" }, { "database": "UniProtKB", "id": "ARBA00058466", "url": "https://www.uniprot.org/uniprotkb/ARBA00058466#function" }, { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FBXL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7", "locus": { "chromosome": "11", "start_pos": 49131665, "end_pos": 49151009, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009472", "url": "https://www.ensembl.org/id/ENSSSCG00000009472" } ] } } ], "crossref": [ { "id": "A0A4X1V7A7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1V7A7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009472", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009472", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22178", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22178", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23957", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23957", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152980", "url": "https://www.ncbi.nlm.nih.gov/gene/100152980", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152980", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152980", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RWNQAFH", "url": "https://omabrowser.org/oma/group/RWNQAFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1V7A7", "url": "https://www.orthodb.org/?gene=A0A4X1V7A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10224:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10224:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003357916", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357916", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A8U4", "url": "https://www.uniprot.org/uniprotkb/A0A287A8U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A8U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A8U4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V7A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRGGGRDSDHNSSEEGTAEKSKKLRTTSEPSQTCDWGNLLQDIILQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIRHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 429, "header": "tr|A0A4X1V7A7-1|A0A4X1V7A7_PIG Isoform 1 of F-box/LRR-repeat protein 21 OS=Sus scrofa OX=9823 GN=FBXL3 PE=4 SV=1 CANONICAL=A0A4X1V7A7-1" }, "isoforms": [ { "isoform_ac": "A0A287A8U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7/entry#A0A287A8U4-1", "sequence": { "sequence": "MKRGGGRDSDHNSSEEGTAEKSKKLRTTSEPSQTCDWGNLLQDIILQVFKYLPLLDRAHASQVCRNWNQVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIRHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 381, "header": "tr|A0A287A8U4-1|A0A4X1V7A7_PIG Computationally mapped isoform of F-box/LRR-repeat protein 21 OS=Sus scrofa OX=9823 GN=FBXL3 PE=4 SV=2 CANONICAL=A0A4X1V7A7-1" }, "locus": { "chromosome": "11", "start_pos": 49145730, "end_pos": 49133552, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039556.2", "url": "https://www.ensembl.org/id/ENSSSCT00000039556.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040298.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040298.2" } ] } }, { "isoform_ac": "A0A4X1V7A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7/entry#A0A4X1V7A7-1", "sequence": { "sequence": "MKRGGGRDSDHNSSEEGTAEKSKKLRTTSEPSQTCDWGNLLQDIILQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIRHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 429, "header": "tr|A0A4X1V7A7-1|A0A4X1V7A7_PIG Isoform 1 of F-box/LRR-repeat protein 21 OS=Sus scrofa OX=9823 GN=FBXL3 PE=4 SV=1 CANONICAL=A0A4X1V7A7-1" }, "locus": { "chromosome": "11", "start_pos": 49145730, "end_pos": 49133552, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059559.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059559.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032594.2", "url": "https://www.ensembl.org/id/ENSSSCP00000032594.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A8U4", "url": "https://www.uniprot.org/uniprotkb/A0A287A8U4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152980", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152980", "resource": "KEGG Pathway" }, { "id": "R-SSC-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q2U3I7-1", "protein_name": "F-box and leucine rich repeat protein 3", "gene_name": "FBXL3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKRGRKTNEANNSSSEETAEKESKRHKSVDERTTVVRSPDWGNLLQDIILQVFQYLPLLDRAHASQVCRSWNQVFHMPDLWRCFEFELNQPATSYLRATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTQFHTIQKSSWDAFIKHSPKVNLVMYFFLYEEEFDPFFRYEIPVTHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKYLSAVGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 433 }, "evidence": [ { "id": "A0A4X1V7A7", "url": "https://omabrowser.org/oma/group/A0A4X1V7A7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7F3X0-1", "protein_name": "F-box/LRR-repeat protein 3", "gene_name": "Fbxl3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKRGGRDSDLDSPEEGTAEKRKKLRTAHECSQPCDWGNLLQDIILQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIKHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 428 }, "evidence": [ { "id": "A0A4X1V7A7", "url": "https://omabrowser.org/oma/group/A0A4X1V7A7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LNB3-1", "protein_name": "F-box and leucine-rich repeat protein 3", "gene_name": "Fbxl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMKRGGRDSDQDSPEEGTAEKPKKPRTTHECSQPCDWGNLLQDIVLHVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIKHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 430 }, "evidence": [ { "id": "A0A4X1V7A7", "url": "https://omabrowser.org/oma/group/A0A4X1V7A7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C4V4-1", "protein_name": "F-box/LRR-repeat protein 3", "gene_name": "Fbxl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRGGRDSDQDSAEEGTAEKPKRPRTTQERSQPCDWGNLLQDIVLHVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIKHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 428 }, "evidence": [ { "id": "A0A4X1V7A7", "url": "https://omabrowser.org/oma/group/A0A4X1V7A7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKT7-1", "protein_name": "F-box/LRR-repeat protein 3", "gene_name": "FBXL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKRGGRDSDRNSSEEGTAEKSKKLRTTNEHSQTCDWGNLLQDIILQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIRHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 428 }, "evidence": [ { "id": "A0A4X1V7A7", "url": "https://omabrowser.org/oma/group/A0A4X1V7A7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "pmid": "" }, { "name": "protein destabilization", "id": "GO:0031648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031648", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "pmid": "" }, { "name": "entrainment of circadian clock by photoperiod", "id": "GO:0043153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043153", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V7A7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1V7A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V7A7" }, { "id": "SM00256", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00256" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 80, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 137, "end_pos": 139 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 361, "end_pos": 363 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TTT3-1", "uniprot_ac": "A0A4X1TTT3", "uniprot_id": "A0A4X1TTT3_PIG", "mass": { "chemical_mass": 81006.0, "monoisotopic_mass": 81006.0 }, "refseq": { "ac": "XP_005669914", "name": "centrosomal protein of 63 kDa isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669914" }, "gene_names": [ { "name": "CEP63", "type": "recommended", "evidence": [ { "id": "A0A4X1TTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ] }, { "name": "CEP63", "type": "synonym", "evidence": [ { "id": "XP_005669914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669914" } ] } ], "protein_names": [ { "name": "Centrosomal protein of 63 kDa", "type": "recommended", "evidence": [ { "id": "A0A4X1TTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 63 kDa isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005669914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669914" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CEP63", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3", "locus": { "chromosome": "13", "start_pos": 75707102, "end_pos": 75605675, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011645", "url": "https://www.ensembl.org/id/ENSSSCG00000011645" } ] } } ], "crossref": [ { "id": "A0A4X1TTT3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TTT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011645", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011645", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100157714", "url": "https://www.ncbi.nlm.nih.gov/gene/100157714", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HYKAGLH", "url": "https://omabrowser.org/oma/group/HYKAGLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A480UUW8", "url": "https://www.orthodb.org/?gene=A0A480UUW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TTT3", "url": "https://www.orthodb.org/?gene=A0A4X1TTT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18875:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18875:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17045", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17045", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005669914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669914", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A9X7", "url": "https://www.uniprot.org/uniprotkb/A0A287A9X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A9X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A9X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480JY41", "url": "https://www.uniprot.org/uniprotkb/A0A480JY41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480JY41-1", "url": "https://www.uniprot.org/uniprotkb/A0A480JY41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480UUW8", "url": "https://www.uniprot.org/uniprotkb/A0A480UUW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480UUW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A480UUW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TTT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1CMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8D1CMQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1CMQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1CMQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1RKV5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1RKV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1RKV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1RKV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALLEGIQNRGHEGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDVRERELKALRSQLDMKHKEVGMLRQQVEEHEKVKQEMAMEYKQELKKLHEELGRLKRSYEKLQKKHVRDFRGNTKNHREDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKTLAEQSEIIQAQLANRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTNMTIMQEQRQKEEKLRESDKLLEVLQEEKRELKAALQTQENFIREARIQKEKLQAKLKAADTQHTLETMRSLEEAQEERGYPSQGQGDLEKVLSRLDFTHTSEELLQAEVTHLEGSLESVSATCKQLSQELMEKYEELKKMEVHNNEYRAEIKKLKEQILQAEQSYSSVLEGMKMEISQLTRELHQRDITIASTKSSSSDMERRLKVEIQKAEEKAVEHKEILNQLESLKLENRHLSEMVMKLELGLHEAKEISLADLQENYIEALNKLVSENQQLQKDLMDTKSQLEISTQMCKKNHDRIFKPTHSRIPVFKPAHGQHRQDGMQTEHYKAGLHSPRGQASDSIEPLSRGLSPARSQISPCCSTMSLPSNFLSKTHSLPSVLDTNETNFSDTISESINDQEDFISSCPLPLSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVKQFTAQK", "length": 698, "header": "tr|A0A4X1TTT3-1|A0A4X1TTT3_PIG Isoform 1 of Centrosomal protein of 63 kDa OS=Sus scrofa OX=9823 GN=CEP63 PE=3 SV=1 CANONICAL=A0A4X1TTT3-1" }, "isoforms": [ { "isoform_ac": "A0A287A9X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3/entry#A0A287A9X7-1", "sequence": { "sequence": "MEALLEGIQNRGHEGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDVRERELKALRSQLDMKHKEEFRQKSLDWEKQRLIYQQQVSSLEAQRKTLAEQSEIIQAQLANRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTNMTIMQEQRQKEEKLRESDKLLEVLQEEKRELKAALQTQENFIREARIQKEKLQAKLKAADTQHTLETMSLESVSATCKQLSQELMEKYEELKKMEVHNNEYRAEIKKLKEQILQAEQSYSSVLEGMKMEISQLTRELHQRDITIASTKSSSSDMERRLKVEIQKAEEKAVEHKEILNQLESLKLENRHLSEMVMKLELGLHECPLPLSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVKQFTAQK", "length": 422, "header": "tr|A0A287A9X7-1|A0A4X1TTT3_PIG Computationally mapped isoform of Centrosomal protein of 63 kDa OS=Sus scrofa OX=9823 GN=CEP63 PE=3 SV=3 CANONICAL=A0A4X1TTT3-1" }, "locus": { "chromosome": "13", "start_pos": 75706750, "end_pos": 75615240, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038688.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038688.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040810.3", "url": "https://www.ensembl.org/id/ENSSSCP00000040810.3" } ] } }, { "isoform_ac": "A0A480JY41-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3/entry#A0A480JY41-1", "sequence": { "sequence": "MEALLEGIQNRGHEGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDVRERELKALRSQLDMKHKEVGMLRQQVEEHEKVKQEMAMEYKQELKKLHEELGRLKRSYEKLQKKHVRDFRGNTKNHREDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKTLAEQSEIIQAQLANRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTNMTIMQEQRQKEEKLRESDKLLEVLQEEKRELKAALQTQENFIREARIQKEKLQAKLKAADTQHTLETMRSLEEAQEERGYPSQGQGDLEKVLSRLDFTHTSEELLQAEVTHLEGSLESVSATCKQLSQELMEKYEELKKMEVHNNEYRAEIKKLKEQILQAEQSYSSVLEGMKMEISQLTRELHQRDITIASTKSSSSDMERRLKVEIQKAEEKAVEHKEILNQLESLKLENRHLSEMVMKLELGLHECPLPLSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVKQFTAQK", "length": 541, "header": "tr|A0A480JY41-1|A0A480JY41_PIG Computationally mapped isoform of Centrosomal protein of 63 kDa OS=Sus scrofa OX=9823 GN=CEP63 PE=3 SV=1 CANONICAL=A0A4X1TTT3-1" }, "locus": { "chromosome": "13", "start_pos": 75706750, "end_pos": 75615240, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044702.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044702.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044298.3", "url": "https://www.ensembl.org/id/ENSSSCP00000044298.3" } ] } }, { "isoform_ac": "A0A480UUW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3/entry#A0A480UUW8-1", "sequence": { "sequence": "MASLGVRSRPASCQNKGDLVMEALLEGIQNRGHEGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDVRERELKALRSQLDMKHKEVGMLRQQVEEHEKVKQEMAMEYKQELKKLHEELGRLKRSYEKLQKKHVRDFRGNTKNHREDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKTLAEQSEIIQAQLANRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTNMTIMQEQRQKEEKLRESDKLLEVLQEEKRELKAALQTQENFIREARIQKEKLQAKLKAADTQHTLETMRSLEEAQEERGYPSQGQGDLEKVLSRLDFTHTSEELLQAEVTHLEGSLESVSATCKQLSQELMEKYEELKKMEVHNNEYRAEIKKLKEQILQAEQSYSSVLEGMKMEISQLTRELHQRDITIASTKSSSSDMERRLKVEIQKAEEKAVEHKEILNQLESLKLENRHLSEMVMKLELGLHECPLPLSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVKQFTAQK", "length": 561, "header": "tr|A0A480UUW8-1|A0A480UUW8_PIG Computationally mapped isoform of Centrosomal protein of 63 kDa OS=Sus scrofa OX=9823 GN=CEP63 PE=3 SV=1 CANONICAL=A0A4X1TTT3-1" }, "locus": { "chromosome": "13", "start_pos": 75706750, "end_pos": 75606113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012746.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012746.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012412.5", "url": "https://www.ensembl.org/id/ENSSSCP00000012412.5" } ] } }, { "isoform_ac": "A0A4X1TTT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3/entry#A0A4X1TTT3-1", "sequence": { "sequence": "MEALLEGIQNRGHEGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDVRERELKALRSQLDMKHKEVGMLRQQVEEHEKVKQEMAMEYKQELKKLHEELGRLKRSYEKLQKKHVRDFRGNTKNHREDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKTLAEQSEIIQAQLANRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTNMTIMQEQRQKEEKLRESDKLLEVLQEEKRELKAALQTQENFIREARIQKEKLQAKLKAADTQHTLETMRSLEEAQEERGYPSQGQGDLEKVLSRLDFTHTSEELLQAEVTHLEGSLESVSATCKQLSQELMEKYEELKKMEVHNNEYRAEIKKLKEQILQAEQSYSSVLEGMKMEISQLTRELHQRDITIASTKSSSSDMERRLKVEIQKAEEKAVEHKEILNQLESLKLENRHLSEMVMKLELGLHEAKEISLADLQENYIEALNKLVSENQQLQKDLMDTKSQLEISTQMCKKNHDRIFKPTHSRIPVFKPAHGQHRQDGMQTEHYKAGLHSPRGQASDSIEPLSRGLSPARSQISPCCSTMSLPSNFLSKTHSLPSVLDTNETNFSDTISESINDQEDFISSCPLPLSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVKQFTAQK", "length": 698, "header": "tr|A0A4X1TTT3-1|A0A4X1TTT3_PIG Isoform 1 of Centrosomal protein of 63 kDa OS=Sus scrofa OX=9823 GN=CEP63 PE=3 SV=1 CANONICAL=A0A4X1TTT3-1" }, "locus": { "chromosome": "13", "start_pos": 75706750, "end_pos": 75615240, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024754.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024754.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023455.2", "url": "https://www.ensembl.org/id/ENSSSCP00000023455.2" } ] } }, { "isoform_ac": "A0A8D1CMQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3/entry#A0A8D1CMQ2-1", "sequence": { "sequence": "MEALLEGIQNRGHEGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDVRERELKALRSQLDMKHKEVGMLRQQVEEHEKVKQEMAMEYKQELKKLHEELGRLKRSYEKLQKKHVRDFRGNTKNHREDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKTLAEQSEIIQAQLANRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTNMTIMQEQRQKEEKLRESDKLLEVLQEEKRELKAALQTQENFIREARIQKEKLQAKLKAADTQHTLETMRSLEEAQEERGYPSQGQGDLEKVLSRLDFTHTSEELLQAEVTHLEGSLESVSATCKQLSQELMEKYEELKKMEVHNNEYRAEIKKLKEQILQAEQSYSSVLEGMKMEISQLTRELHQRDITIASTKSSSSDMERRLKVEIQKAEEKAVEHKEILNQLESLKLENRHLSEMVMKLELGLHEFKSNCEMLLLQKLSQIKRSQDT", "length": 511, "header": "tr|A0A8D1CMQ2-1|A0A4X1TTT3_PIG Computationally mapped isoform of Centrosomal protein of 63 kDa OS=Sus scrofa OX=9823 GN=CEP63 PE=3 SV=1 CANONICAL=A0A4X1TTT3-1" }, "locus": { "chromosome": "13", "start_pos": 75697813, "end_pos": 75615240, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088194.1", "url": "https://www.ensembl.org/id/ENSSSCT00000088194.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068763.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068763.1" } ] } }, { "isoform_ac": "A0A8D1RKV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3/entry#A0A8D1RKV5-1", "sequence": { "sequence": "MEALLEGIQNRGHEGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDVRERELKALRSQLDMKHKEVGMLRQQVEEHEKVKQEMAMEYKQELKKLHEEEFRQKSLDWEKQRLIYQQQVSSLEAQRKTLAEQSEIIQAQLANRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTNMTIMQEQRQKEEKLRESDKLLEVLQEEKRELKAALQTQENFIREARIQKEKLQAKLKAADTQHTLETMRSLEEAQEERGYPSQGQGDLEKVLSRLDFTHTSEELLQAEVTHLEGSLESVSATCKQLSQELMEKYEELKKMEVHNNEYRAEIKKLKEQILQAEQSYSSVLEGMKMEISQLTRELHQRDITIASTKSSSSDMERRLKVEIQKAEEKAVEHKEILNQLESLKLENRHLSEMVMKLELGLHECPLPLSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVKQFTAQK", "length": 500, "header": "tr|A0A8D1RKV5-1|A0A4X1TTT3_PIG Computationally mapped isoform of Centrosomal protein of 63 kDa OS=Sus scrofa OX=9823 GN=CEP63 PE=3 SV=1 CANONICAL=A0A4X1TTT3-1" }, "locus": { "chromosome": "13", "start_pos": 75706750, "end_pos": 75615240, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064932.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064932.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052508.3", "url": "https://www.ensembl.org/id/ENSSSCP00000052508.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1CMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8D1CMQ2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-SSC-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-SSC-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-SSC-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-SSC-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-SSC-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-SSC-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BDP9-1", "protein_name": "Centrosomal protein of 63 kDa", "gene_name": "CEP63", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEALLEGIQNRGHDGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDIRERELKALRSQLDLKHKEIGMLRQQVEKHEKVKQEMAMEYKQELKKLHEELSRLKRSYEKLQKKHVRDFRGNAKNHREDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLANRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTNMTIMQEQRQKEEKLKESEKMLEVLQEEKRGLKAALQTQENFIHDARIQKEKLQAKLKAVDTQHTVETIRSLEEPLAERRYASQGQGDLQNVLCQLDFTHTSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYGELKKMEVHNNEYRAEIKKLKEQILQAEQSYSSVLEGMKMEISQLTRELHQRDITIASTKSSSSDMEKRLKAEIQKAEEKAVEHKEMLGQLESLKLENRHLSEMVMKLELGLHEAKEISLADLQENYIEALNKLVSENQQLQKDLMDTKGQLEISTQICKKNRDRIFKPTYSRVPEFKNTEFKPAHGQHRHDGMKAEPYKAGLHSPQGQASDSIEPVSLSRGFSPPSHQISSCCSTVSLPSNFLCKTNSLPSVLDTNETNFSDTVSESINDPEDFTSSCPLPLSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVKQFTVLK", "length": 705 }, "evidence": [ { "id": "A0A4X1TTT3", "url": "https://omabrowser.org/oma/group/A0A4X1TTT3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UPP8-1", "protein_name": "Centrosomal protein of 63 kDa", "gene_name": "Cep63", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEALLEGIQNRGHSGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDIRDRELKALRSQLDMKHKEVGILHQQIEEHEKTKQEMAMEYKEELLKLQEELSRLKRSYEKLQKKQLREFRGNTKSFREDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLANRKQKLESVELSSQSEIQHLNSKLERAKDTICANELEIERLNIRVNDLMGTNMTILQDHRQKEEKLRESEKLLEALQEEQKELKASLQSQETFILEAKMQEKLQTTLKAVGTQQSVERPLEDCQKERKYSSPGQGVLDNVLSQLDFSHSSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYEELKRMEGHNNEYRTEIKKLKEQILQADQTYSSALEGMKMEISQLTRELHQRDITIASAKCSSSDMEKQLKAEMQKAEEKAVEHKEILSQLESLKLENHRLSETVMKLELGLHEAKEISLADLQENYIEALNKLVSENQQLQKDLMSTKSELEHATNMCKKKDGEIFNPAHSRAAGFKNAELKPIHGQHRHDGIKTEQYKTGHHSPRGQTLDSIDPVARGPSPLSSHISPGSSTVSLPSNFLFEAHSLPSVLDINDVNFSDSLSDCMNDQEEFVSSGSLPTSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVRQFTALV", "length": 700 }, "evidence": [ { "id": "A0A4X1TTT3", "url": "https://omabrowser.org/oma/group/A0A4X1TTT3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4KLY0-1", "protein_name": "Centrosomal protein of 63 kDa", "gene_name": "Cep63", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEALLEGIQTRGHSGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDMRDRELKALRSQLDMKHKEVGILHQQIEEQEKTKQEMALEYKEELMKLQEELSRLKRSYEKLQKKQLREFRGNTKSLREDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLANRKQKLESVELSSQSEIQHLSSKLERAKDTICANELEIERLNIRVKDLMGTNVTILQEQRQKEEKLRESEKLLEALQEEQKELKASLQAQESFILDAKMQEKLQTKLKAVDTKHSVERSLEDCQVERKYSSSGQGVLDNVLSQLDISHSSEELLQAEVTRLEGSLESVSTTCKQLSQELMEKYEELKRMEGHNNEYRTEIKKLKEQILQADQTYSSALEGMKTEISQLTRELHQRDITIASAKCSSSDMERQLKAEMQKAEEKAVEHKEILSQLESLRLENRRLSETVMKLELGLHECSMPVSPLGLIATRFLEEEELRSHHILERLDAHIEELKRESEKTVRQFTALV", "length": 538 }, "evidence": [ { "id": "A0A4X1TTT3", "url": "https://omabrowser.org/oma/group/A0A4X1TTT3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96MT8-1", "protein_name": "Centrosomal protein of 63 kDa", "gene_name": "CEP63", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEALLEGIQNRGHGGGFLTSCEAELQELMKQIDIMVAHKKSEWEGRTHALETCLKIREQELKSLRSQLDVTHKEVGMLHQQVEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQKKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQEKVKATNTQHAVEAIRPREESLAEKKYTSQGQGDLDSVLSQLNFTHTSEDLLQAEVTCLEGSLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQSYSSALEGMKMEISHLTQELHQRDITIASTKGSSSDMEKRLRAEMQKAEDKAVEHKEILDQLESLKLENRHLSEMVMKLELGLHEAKEISLADLQENYIEALNKLVSENQQLQKDLMNTKSQLEISTQMCKKQNDRIFKPTHSRTTEFKNTEFKPTHGQHRHDGIKTEHYKTDLHSPRGQASDSINPMSRVLSPLSPQISPCSSTRSLTSYSLCKTHSLPSALDTNEANFSDTMSESMNDQEEFISSCSLPVSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVRQFTALK", "length": 703 }, "evidence": [ { "id": "A0A4X1TTT3", "url": "https://omabrowser.org/oma/group/A0A4X1TTT3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ], "pmid": "" }, { "name": "negative regulation of innate immune response", "id": "GO:0045824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045824", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ], "pmid": "" }, { "name": "de novo centriole assembly involved in multi-ciliated epithelial cell differentiation", "id": "GO:0098535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098535", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ], "pmid": "" }, { "name": "negative regulation of protein K63-linked ubiquitination", "id": "GO:1900045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900045", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTT3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" }, { "id": "PF25771", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25771" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CEP63/Deup1 CEP152 binding coiled coil", "eco_id": "ECO_0000259", "start_pos": 659, "end_pos": 694, "start_aa": "Thr", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT3" }, { "id": "PF17045", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17045" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CEP63/Deup1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 280, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 625, "end_pos": 627 }, { "start_pos": 628, "end_pos": 630 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VEC8-1", "uniprot_ac": "A0A4X1VEC8", "uniprot_id": "A0A4X1VEC8_PIG", "mass": { "chemical_mass": 281399.0, "monoisotopic_mass": 281399.0 }, "refseq": { "ac": "XP_020924720", "name": "filamin-B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924720" }, "gene_names": [ { "name": "FLNB", "type": "recommended", "evidence": [ { "id": "A0A4X1VEC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" } ] }, { "name": "FLNB", "type": "synonym", "evidence": [ { "id": "XP_020924720", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924720" } ] } ], "protein_names": [ { "name": "Filamin B", "type": "synonym", "evidence": [ { "id": "A0A4X1VEC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8/entry#names_and_taxonomy" } ] }, { "name": "filamin-B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020924720", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924720" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEC8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FLNB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8", "locus": { "chromosome": "13", "start_pos": 39938746, "end_pos": 39789739, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011471", "url": "https://www.ensembl.org/id/ENSSSCG00000011471" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011471", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011471", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21309", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21309", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21313", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21313", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100514491", "url": "https://www.ncbi.nlm.nih.gov/gene/100514491", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514491", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514491", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1VEC8", "url": "https://www.orthodb.org/?gene=A0A4X1VEC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38537:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38537:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00630", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00630", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1169408", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1169408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020924720", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924720", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AHQ3", "url": "https://www.uniprot.org/uniprotkb/A0A287AHQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AHQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AHQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VEC8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VEC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VJL0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VJL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0R017", "url": "https://www.uniprot.org/uniprotkb/A0A8D0R017", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0R017-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0R017-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKHMYRKYHQRPTFRQMQLENVSVALEFLDRENIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAHVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLEASGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVIKVSFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGIRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSIAIMWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPASGDYNPDLVQAYGPGLEKSGCIVDNLAEFTVDPKNAGKAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPVKPIKHTIAVVWGGVNIPNSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVRVDPSHDASKVKAEGPGLSKSGVENGKPTHFTVYTKGAGKAPLNVQFSSPLPGDAVKDLDVIDNYDYSHTVKYTPTQQGTMQVLVTYGGDPIPKSPFTVGVAAPLDLSRIKVNGLENRVEVGKDQEFAIDTRGAGGQGKLDVTILSPSRKVVPCLVAPVAGRESSTAKFIPREEGLYAVDVTYDGHPVPGSPYMVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGTLGLEAVSDSGAKAEVCIENNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRVKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARILQSFTVDSSKAGLAPLEVRVLGPRAVETDSQSRRSPLKAISEFFKRDLKGDFMETGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSTYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVAAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSEFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEIDSSDMSAHVTSPSGRVTEAEIVPVGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLIGVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKEKGDYVLAVKWGEEHIPGSPFHVTVP", "length": 2633, "header": "tr|A0A4X1VEC8-1|A0A4X1VEC8_PIG Isoform 1 of Filamin B OS=Sus scrofa OX=9823 GN=FLNB PE=1 SV=1 CANONICAL=A0A4X1VEC8-1" }, "isoforms": [ { "isoform_ac": "A0A287AHQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8/entry#A0A287AHQ3-1", "sequence": { "sequence": "MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKHMYRKYHQRPTFRQMQLENVSVALEFLDRENIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAHVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLEASGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVIKVSFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGIRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSIAIMWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPASGDYNPDLVQAYGPGLEKSGCIVDNLAEFTVDPKNAGKAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPVKPIKHTIAVVWGGVNIPNSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVRVDPSHDASKVKAEGPGLSKSGVENGKPTHFTVYTKGAGKAPLNVQFSSPLPGDAVKDLDVIDNYDYSHTVKYTPTQQGTMQVLVTYGGDPIPKSPFTVGVAAPLDLSRIKVNGLENRVEVGKDQEFAIDTRGAGGQGKLDVTILSPSRKVVPCLVAPVAGRESSTAKFIPREEGLYAVDVTYDGHPVPGSPYMVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGTLGLEAVSDSGAKAEVCIENNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRVKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARILQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSTYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITESQEGSPIPLCASVSSSCFLPFTAPPALINPSLCSHPGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSEFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPGLKVMSCCPDPVGLEGAVLCCPR", "length": 2105, "header": "tr|A0A287AHQ3-1|A0A4X1VEC8_PIG Computationally mapped isoform of Filamin B OS=Sus scrofa OX=9823 GN=FLNB PE=1 SV=2 CANONICAL=A0A4X1VEC8-1" }, "locus": { "chromosome": "13", "start_pos": 39919020, "end_pos": 39789898, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041927.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041927.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043422.2", "url": "https://www.ensembl.org/id/ENSSSCP00000043422.2" } ] } }, { "isoform_ac": "A0A4X1VEC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8/entry#A0A4X1VEC8-1", "sequence": { "sequence": "MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKHMYRKYHQRPTFRQMQLENVSVALEFLDRENIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAHVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLEASGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVIKVSFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGIRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSIAIMWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPASGDYNPDLVQAYGPGLEKSGCIVDNLAEFTVDPKNAGKAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPVKPIKHTIAVVWGGVNIPNSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVRVDPSHDASKVKAEGPGLSKSGVENGKPTHFTVYTKGAGKAPLNVQFSSPLPGDAVKDLDVIDNYDYSHTVKYTPTQQGTMQVLVTYGGDPIPKSPFTVGVAAPLDLSRIKVNGLENRVEVGKDQEFAIDTRGAGGQGKLDVTILSPSRKVVPCLVAPVAGRESSTAKFIPREEGLYAVDVTYDGHPVPGSPYMVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGTLGLEAVSDSGAKAEVCIENNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRVKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARILQSFTVDSSKAGLAPLEVRVLGPRAVETDSQSRRSPLKAISEFFKRDLKGDFMETGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSTYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVAAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSEFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEIDSSDMSAHVTSPSGRVTEAEIVPVGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLIGVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKEKGDYVLAVKWGEEHIPGSPFHVTVP", "length": 2633, "header": "tr|A0A4X1VEC8-1|A0A4X1VEC8_PIG Isoform 1 of Filamin B OS=Sus scrofa OX=9823 GN=FLNB PE=1 SV=1 CANONICAL=A0A4X1VEC8-1" }, "locus": { "chromosome": "13", "start_pos": 39937296, "end_pos": 39789898, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040435.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040435.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056889.1", "url": "https://www.ensembl.org/id/ENSSSCP00000056889.1" } ] } }, { "isoform_ac": "A0A4X1VJL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8/entry#A0A4X1VJL0-1", "sequence": { "sequence": "MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKHMYRKYHQRPTFRQMQLENVSVALEFLDRENIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAHVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLEASGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVIKVSFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGIRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSIAIMWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPASGDYNPDLVQAYGPGLEKSGCIVDNLAEFTVDPKNAGKAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPVKPIKHTIAVVWGGVNIPNSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVRVDPSHDASKVKAEGPGLSKSGVENGKPTHFTVYTKGAGKAPLNVQFSSPLPGDAVKDLDVIDNYDYSHTVKYTPTQQGTMQVLVTYGGDPIPKSPFTVGVAAPLDLSRIKVNGLENRVEVGKDQEFAIDTRGAGGQGKLDVTILSPSRKVVPCLVAPVAGRESSTAKFIPREEGLYAVDVTYDGHPVPGSPYMVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGTLGLEAVSDSGAKAEVCIENNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRVKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARILQSFTVDSSKAGLAPLEVRVLGPRAVETDSQSRRSPLKAISEFFKRDLKGDFMETGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSTYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSEFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEIDSSDMSAHVTSPSGRVTEAEIVPVGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLIGVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKEKGDYVLAVKWGEEHIPGSPFHVTVP", "length": 2609, "header": "tr|A0A4X1VJL0-1|A0A4X1VEC8_PIG Computationally mapped isoform of Filamin B OS=Sus scrofa OX=9823 GN=FLNB PE=1 SV=1 CANONICAL=A0A4X1VEC8-1" }, "locus": { "chromosome": "13", "start_pos": 39937296, "end_pos": 39789898, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044709.2", "url": "https://www.ensembl.org/id/ENSSSCT00000044709.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033365.1", "url": "https://www.ensembl.org/id/ENSSSCP00000033365.1" } ] } }, { "isoform_ac": "A0A8D0R017-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8/entry#A0A8D0R017-1", "sequence": { "sequence": "MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKHMYRKYHQRPTFRQMQLENVSVALEFLDRENIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAHVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLEASGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVIKVSFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGIRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSIAIMWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPASGDYNPDLVQAYGPGLEKSGCIVDNLAEFTVDPKNAGKAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPVKPIKHTIAVVWGGVNIPNSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVRVDPSHDASKVKAEGPGLSKSGVENGKPTHFTVYTKGAGKAPLNVQFSSPLPGDAVKDLDVIDNYDYSHTVKYTPTQQGTMQVLVTYGGDPIPKSPFTVGVAAPLDLSRIKVNGLENRVEVGKDQEFAIDTRGAGGQGKLDVTILSPSRKVVPCLVAPVAGRESSTAKFIPREEGLYAVDVTYDGHPVPGSPYMVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGTLGLEAVSDSGAKAEVCIENNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRVKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARILQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSTYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVAAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSEFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEIDSSDMSAHVTSPSGRVTEAEIVPVGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLIGVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKEKGDYVLAVKWGEEHIPGSPFHVTVP", "length": 2549, "header": "tr|A0A8D0R017-1|A0A4X1VEC8_PIG Computationally mapped isoform of Filamin B OS=Sus scrofa OX=9823 GN=FLNB PE=1 SV=1 CANONICAL=A0A4X1VEC8-1" }, "locus": { "chromosome": "13", "start_pos": 39937296, "end_pos": 39789898, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012553.3", "url": "https://www.ensembl.org/id/ENSSSCT00000012553.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012224.3", "url": "https://www.ensembl.org/id/ENSSSCP00000012224.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 519, "start_aa": "Thr", "end_pos": 519, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr519", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VJL0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VJL0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514491", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514491", "resource": "KEGG Pathway" }, { "id": "R-SSC-1169408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1169408", "resource": "Reactome", "description": "ISG15 antiviral mechanism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEC8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEC8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEC8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEC8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEC8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEC8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEC8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEC8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEC8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VEC8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1398, "end_pos": 1400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1868, "end_pos": 1870, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2276, "end_pos": 2278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2393, "end_pos": 2395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2439, "end_pos": 2441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2514, "end_pos": 2516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2601, "end_pos": 2603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1VEC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VEC8" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 122, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 519 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1398, "end_pos": 1400 }, { "start_pos": 1868, "end_pos": 1870 }, { "start_pos": 2276, "end_pos": 2278 }, { "start_pos": 2393, "end_pos": 2395 }, { "start_pos": 2439, "end_pos": 2441 }, { "start_pos": 2514, "end_pos": 2516 }, { "start_pos": 2601, "end_pos": 2603 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 79, "end_pos": 81 }, { "start_pos": 804, "end_pos": 806 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UXM0-1", "uniprot_ac": "A0A4X1UXM0", "uniprot_id": "A0A4X1UXM0_PIG", "mass": { "chemical_mass": 66566.0, "monoisotopic_mass": 66566.0 }, "refseq": {}, "gene_names": [ { "name": "AIFM3", "type": "recommended", "evidence": [ { "id": "A0A4X1UXM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0" } ] } ], "protein_names": [ { "name": "Apoptosis-inducing factor 3", "type": "recommended", "evidence": [ { "id": "A0A4X1UXM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0/entry#names_and_taxonomy" } ] }, { "name": "Apoptosis-inducing factor-like protein", "type": "synonym", "evidence": [ { "id": "A0A4X1UXM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AMS9", "url": "https://www.uniprot.org/uniprotkb/A0A287AMS9#function" }, { "database": "UniProtKB", "id": "ARBA00058975", "url": "https://www.uniprot.org/uniprotkb/ARBA00058975#function" }, { "database": "UniProtKB", "id": "A0A287BJF2", "url": "https://www.uniprot.org/uniprotkb/A0A287BJF2#function" }, { "database": "UniProtKB", "id": "A0A4X1UXM0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UXM0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AIFM3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0", "locus": { "chromosome": "14", "start_pos": 50576275, "end_pos": 50562776, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010096", "url": "https://www.ensembl.org/id/ENSSSCG00000010096" } ] } } ], "crossref": [ { "id": "A0A4X1UXM0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UXM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010096", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010096", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03478", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03478", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100525540", "url": "https://www.ncbi.nlm.nih.gov/gene/100525540", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050446", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050446", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525540", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525540", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PRCTHYG", "url": "https://omabrowser.org/oma/group/PRCTHYG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287AMS9", "url": "https://www.orthodb.org/?gene=A0A287AMS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43557", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43557", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43557:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43557:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00355", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00355", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07992", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07992", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AMS9", "url": "https://www.uniprot.org/uniprotkb/A0A287AMS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AMS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BJF2", "url": "https://www.uniprot.org/uniprotkb/A0A287BJF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BJF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BJF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UXM0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UXM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKDRKEELSASGKGSPRAYQGNGTARHFHAEERLPAPHPYPGAQDFMEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKVMATCISPSAGHSGSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRPKEFFRAHGIEVLTEAQVVTVDVRNKKAVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRLLGERVGRALMKMFENNRVKFYMQTEVLELRAQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEISTVPYLWTAMFGKSLRYAGYGEGFDDVVIQGDLHELKFVAFYTKGDEVISVASMNYDPIVSKVAEVLASGRSIRKREVELFLLHSKTGDMSWLTGKGS", "length": 604, "header": "tr|A0A4X1UXM0-1|A0A4X1UXM0_PIG Isoform 1 of Apoptosis-inducing factor 3 OS=Sus scrofa OX=9823 GN=AIFM3 PE=3 SV=1 CANONICAL=A0A4X1UXM0-1" }, "isoforms": [ { "isoform_ac": "A0A287AMS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0/entry#A0A287AMS9-1", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKDRKEELSASGKGSPRAYQGNGTARHFHAEERLPAPHPYPGAQDFMEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKVMATCISPSAGHSGSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRPKEFFRAHGIEVLTEAQVVTVDVRNKKAVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRLLGERVGRALMKMFENNRVKFYMQTEVLELRAQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEISTVPYLWTAMFGKSLRYAGYGEGFDDVVIQGDLHELKFVAFYTKGDEVISVASMNYDPIVSKVAEVLASGRSIRKREVETGDMSWLTGKGS", "length": 597, "header": "tr|A0A287AMS9-1|A0A4X1UXM0_PIG Computationally mapped isoform of Apoptosis-inducing factor 3 OS=Sus scrofa OX=9823 GN=AIFM3 PE=3 SV=3 CANONICAL=A0A4X1UXM0-1" }, "locus": { "chromosome": "14", "start_pos": 50575963, "end_pos": 50565001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060916.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060916.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045195.3", "url": "https://www.ensembl.org/id/ENSSSCP00000045195.3" } ] } }, { "isoform_ac": "A0A287BJF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0/entry#A0A287BJF2-1", "sequence": { "sequence": "MGGCFSKPKPGTPMPAVELKIEVVLPEKDRKEELSASGKGSPRAYQGNGTARHFHAEERLPAPHPYPGAQDFMEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKVMATCISPSAGHSGSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRPKEFFRAHGIEVLTEAQVVTVDVRNKKAVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRLLGERVGRALMKMFENNRVKFYMQTEVLELRAQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEISTVPYLWTAMFGKSLRYAGYGEGFDDVVIQGDLHELKFVAFYTKGDEVISVASMNYDPIVSKVAEVLASGRSIRKREVETGDMSWLTGKGS", "length": 603, "header": "tr|A0A287BJF2-1|A0A287BJF2_PIG Computationally mapped isoform of Apoptosis-inducing factor 3 OS=Sus scrofa OX=9823 GN=AIFM3 PE=3 SV=3 CANONICAL=A0A4X1UXM0-1" }, "locus": { "chromosome": "14", "start_pos": 50575963, "end_pos": 50565001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039795.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039795.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056737.3", "url": "https://www.ensembl.org/id/ENSSSCP00000056737.3" } ] } }, { "isoform_ac": "A0A4X1UXM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0/entry#A0A4X1UXM0-1", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKDRKEELSASGKGSPRAYQGNGTARHFHAEERLPAPHPYPGAQDFMEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKVMATCISPSAGHSGSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRPKEFFRAHGIEVLTEAQVVTVDVRNKKAVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRLLGERVGRALMKMFENNRVKFYMQTEVLELRAQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEISTVPYLWTAMFGKSLRYAGYGEGFDDVVIQGDLHELKFVAFYTKGDEVISVASMNYDPIVSKVAEVLASGRSIRKREVELFLLHSKTGDMSWLTGKGS", "length": 604, "header": "tr|A0A4X1UXM0-1|A0A4X1UXM0_PIG Isoform 1 of Apoptosis-inducing factor 3 OS=Sus scrofa OX=9823 GN=AIFM3 PE=3 SV=1 CANONICAL=A0A4X1UXM0-1" }, "locus": { "chromosome": "14", "start_pos": 50575963, "end_pos": 50565001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011057.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011057.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010769.5", "url": "https://www.ensembl.org/id/ENSSSCP00000010769.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AMS9", "url": "https://www.uniprot.org/uniprotkb/A0A287AMS9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525540", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525540", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LZF1-1", "protein_name": "Apoptosis-inducing factor 3", "gene_name": "AIFM3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKDRGKEELSTGSRGSPRAYQGNGAARHFHADERLPTAHPYPGAQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGELHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNVSTGDLEDFPGLDSLHKFQVKIEKEKVYIRASKQALQLQRRTKVMATCISPSAGYSGSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDAQPEQLALRPKEFFRAHGIEVLTEAQVVTVDVRNKKAVFKDGFKLEYSKLLLAPGSSPKTLSCKGKDVENVFTIRTPEDANRVVRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVEVEETPFRRFLGERVGHTLMKMFENNRVKFYMQTEVSELRAQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGISLDSRGFIPVNKMMQTNIPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEISTVPFLWTAMFGKSLRYAGYGEGFDDVIIQGDLDELKFVAFYTKGDEVISVASMNYDPIVSKVAEVLASGRTIRKREVELFVLHSKTGDMSWLTGKGS", "length": 605 }, "evidence": [ { "id": "A0A4X1UXM0", "url": "https://omabrowser.org/oma/group/A0A4X1UXM0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2N0N1-1", "protein_name": "Apoptosis-inducing factor 3", "gene_name": "Aifm3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHAEERLPTPQPYPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLLKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVTVRASKQALQLQRRTKVMAKCISPSAGHSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSKSLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSSPKTLNCKGKDVENVFTIRTPEDANHVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVLELRAQEGKLQEVVLKSSKVLRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNIPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRTIRKREVETGDMSWLTGRGS", "length": 598 }, "evidence": [ { "id": "A0A4X1UXM0", "url": "https://omabrowser.org/oma/group/A0A4X1UXM0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8M2BC75-1", "protein_name": "Apoptosis-inducing factor 3 isoform X1", "gene_name": "aifm3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGCLSKPKPVEVKVELTLLDKEKEVDLMSPNGKASPFSECRPNGSLGHCSDEDSMTLRPQRKNRDYIEASVCHIKDLENGQMREVDLGAGRALLIKEHGEFFAMGHKCPHYGAPLVKGVLSKGHVRCPWHGACFNIATGDIEDFPGLDSLPTFQVRVEKEKVIIRANKQALQTQRRSKVMSKCSAVINSSTGFSHVLIIGSGPAGLVCAETLRQEGFTDRIVICTTDKHLPYDRPKLSKSLESTAEQLQLRSSDFFQMHDIEVLLEKEVVSVDVKTHTVTFRDGFKMEYRKLFIATGSRPKPLSYKGKDVGNVFHLRTPEDANSIVTLASSKNAVIIGTSFIGMEVAAALTDKAHSVSVIGIEAVPFRKALGEKVGKALMKLFEANRVKFYMLNEVWEMRGHNGQLKEVVLKSGKVLRADVCVIGIGSSPATAFLKQSGVHIDSKGFIPVNKTMQTNIDGVFAGGDVVTFPLALRSNKKVNIPHWQMAHVHGRLAALGIMGKASDIKTVPYFWTAMFGKSIRYAGYGDGFDDVVIQGDLDELKFVAFYTKSEEVVAVASMNYDPIVSRVAEVFGSGKTIRKRDVETGDMSWLIVKGSQ", "length": 599 }, "evidence": [ { "id": "A0A4X1UXM0", "url": "https://omabrowser.org/oma/group/A0A4X1UXM0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZF03-1", "protein_name": "Apoptosis-inducing factor 3", "gene_name": "Aifm3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRGYQGNGTARHFHAEERLPTPQPYPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNIGTGDLEDFPGLDSLHKFQVKIEKEKVTVRASKQALQLQRRTKVMAKCISPSAGHSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSKSLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSSPKTLTCKGKDIENVFTIRTPEDANRVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRAQEGKLQEVVLKSSKVLRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNIPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFMLHSKTGDMSWLTGKGS", "length": 604 }, "evidence": [ { "id": "A0A4X1UXM0", "url": "https://omabrowser.org/oma/group/A0A4X1UXM0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TY86-1", "protein_name": "Apoptosis-inducing factor 3", "gene_name": "Aifm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRGYQGNGTARHFHAEERLPTPQPYPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVTIRASKQALQLQRRTKVMAKCISPSAGHSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSKSLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSSPKTLTCKGKDVENVFTIRTPEDANRVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRAQEGKLQEVVLKSSKVLRADVCVLGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKSDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFMLHSKTGDMSWLTGKGS", "length": 605 }, "evidence": [ { "id": "A0A4X1UXM0", "url": "https://omabrowser.org/oma/group/A0A4X1UXM0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96NN9-1", "protein_name": "Apoptosis-inducing factor 3", "gene_name": "AIFM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHPYPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKVMAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFVLHSKTGDMSWLTGKGS", "length": 605 }, "evidence": [ { "id": "A0A4X1UXM0", "url": "https://omabrowser.org/oma/group/A0A4X1UXM0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LFA3-1", "protein_name": "Monodehydroascorbate reductase 1, peroxisomal", "gene_name": "MDAR1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEKSFKYIILGGGVSAGYAAKEFANQGVQPGELAVISKEAVAPYERPALSKGYLFPEGAARLPGFHCCVGSGGEKLLPESYKQKGIELILSTEIVKADLSAKSLVSATGDVFKYQTLIIATGSTVLRLTDFGVKGADSKNILYLREIDDADKLVEAIKAKKGGKAVVVGGGYIGLELSAVLRINNLDVTMVFPEPWCMPRLFTADIAAFYETYYTNKGVKIIKGTVASGFTAQPNGEVKEVQLKDGRTLEADIVIVGVGAKPLTSLFKGQVEEDKGGIKTDAFFKTSVPDVYAVGDVATFPLKMYGDVRRVEHVDHSRKSAEQAVKAIKAAEGGAAVEEYDYLPFFYSRSFDLSWQFYGDNVGDSVLFGDSNPSNPKPRFGAYWVQGGKVVGAFMEGGSGDENKALAKVAKARPSAESLDELVKQGISFAAKI", "length": 434 }, "evidence": [ { "id": "A0A4X1UXM0", "url": "https://omabrowser.org/oma/group/A0A4X1UXM0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UXM0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UXM0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UXM0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UXM0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UXM0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UXM0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on NAD(P)H", "id": "GO:0016651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016651", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UXM0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UXM0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0" } ], "pmid": "" }, { "name": "execution phase of apoptosis", "id": "GO:0097194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097194", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UXM0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UXM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UXM0" }, { "id": "PS51296", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51296" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rieske", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 164, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 42, "end_pos": 44 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TVP3-1", "uniprot_ac": "A0A4X1TVP3", "uniprot_id": "A0A4X1TVP3_PIG", "mass": { "chemical_mass": 74806.0, "monoisotopic_mass": 74806.0 }, "refseq": {}, "gene_names": [ { "name": "IVNS1ABP", "type": "recommended", "evidence": [ { "id": "A0A4X1TVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3" } ] } ], "protein_names": [ { "name": "Influenza virus NS1A binding protein", "type": "synonym", "evidence": [ { "id": "A0A4X1TVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IVNS1ABP", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3", "locus": { "chromosome": "9", "start_pos": 126453155, "end_pos": 126479587, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015570", "url": "https://www.ensembl.org/id/ENSSSCG00000015570" } ] } } ], "crossref": [ { "id": "A0A4X1TVP3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TVP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015570", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015570", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18306", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18306", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18502", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18502", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AN66", "url": "https://www.uniprot.org/uniprotkb/A0A287AN66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AN66-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AN66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TVP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TVP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHRVSHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISSSSIGCLSSPNATVQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLTKSLSFEMQPDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYDPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDPNIDDWTPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPITKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIASMNVARRGAGVAVLGGKLFVGGGFDGSHAISCVEMYDPARNEWRMMGNMTSPRSNAGITTVGNTIYAVGGFDGNEFLNTVEVYNLEWSCLNPFLRSGHVSGHISIFTVERMLMLCPGPSSKGLKVALASS", "length": 673, "header": "tr|A0A4X1TVP3-1|A0A4X1TVP3_PIG Isoform 1 of Influenza virus NS1A binding protein OS=Sus scrofa OX=9823 GN=IVNS1ABP PE=1 SV=1 CANONICAL=A0A4X1TVP3-1" }, "isoforms": [ { "isoform_ac": "A0A287AN66-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3/entry#A0A287AN66-1", "sequence": { "sequence": "MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHRVSHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLEDNVCLPSNGKLYTKVQTLYYSADHKLLDGNLLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISSSSIGCLSSPNATVQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLTKSLSFEMQPDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYDPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDPNIDDWTPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPITKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIASMNVARRGAGVAVLGGKLFVGGGFDGSHAISCVEMYDPARNEWRMMGNMTSPRSNAGITTVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKTFQF", "length": 620, "header": "tr|A0A287AN66-1|A0A4X1TVP3_PIG Computationally mapped isoform of Influenza virus NS1A binding protein OS=Sus scrofa OX=9823 GN=IVNS1ABP PE=1 SV=2 CANONICAL=A0A4X1TVP3-1" }, "locus": { "chromosome": "9", "start_pos": 126472382, "end_pos": 126460758, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043629.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043629.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045503.3", "url": "https://www.ensembl.org/id/ENSSSCP00000045503.3" } ] } }, { "isoform_ac": "A0A4X1TVP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3/entry#A0A4X1TVP3-1", "sequence": { "sequence": "MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHRVSHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISSSSIGCLSSPNATVQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLTKSLSFEMQPDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYDPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDPNIDDWTPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPITKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIASMNVARRGAGVAVLGGKLFVGGGFDGSHAISCVEMYDPARNEWRMMGNMTSPRSNAGITTVGNTIYAVGGFDGNEFLNTVEVYNLEWSCLNPFLRSGHVSGHISIFTVERMLMLCPGPSSKGLKVALASS", "length": 673, "header": "tr|A0A4X1TVP3-1|A0A4X1TVP3_PIG Isoform 1 of Influenza virus NS1A binding protein OS=Sus scrofa OX=9823 GN=IVNS1ABP PE=1 SV=1 CANONICAL=A0A4X1TVP3-1" }, "locus": { "chromosome": "9", "start_pos": 126472382, "end_pos": 126453158, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016961.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016961.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016507.5", "url": "https://www.ensembl.org/id/ENSSSCP00000016507.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AN66", "url": "https://www.uniprot.org/uniprotkb/A0A287AN66" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVP3" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 99, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 279, "end_pos": 281 }, { "start_pos": 299, "end_pos": 301 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 591, "end_pos": 593 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U5M2-1", "uniprot_ac": "A0A4X1U5M2", "uniprot_id": "A0A4X1U5M2_PIG", "mass": { "chemical_mass": 113528.0, "monoisotopic_mass": 113528.0 }, "refseq": { "ac": "XP_020957963", "name": "disks large homolog 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957963" }, "gene_names": [ { "name": "DLG2", "type": "recommended", "evidence": [ { "id": "A0A4X1U5M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2" } ] }, { "name": "DLG2", "type": "synonym", "evidence": [ { "id": "XP_020957963", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957963" } ] } ], "protein_names": [ { "name": "Discs large MAGUK scaffold protein 2", "type": "synonym", "evidence": [ { "id": "A0A4X1U5M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2/entry#names_and_taxonomy" } ] }, { "name": "disks large homolog 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020957963", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957963" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5M2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DLG2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2", "locus": { "chromosome": "9", "start_pos": 17576135, "end_pos": 19545916, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014904", "url": "https://www.ensembl.org/id/ENSSSCG00000014904" } ] } } ], "crossref": [ { "id": "A0A4X1U5M2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U5M2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014904", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014904", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06723", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06723", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06724", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06724", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06795", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06795", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12032", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12032", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100516384", "url": "https://www.ncbi.nlm.nih.gov/gene/100516384", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09058", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09058", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020957963", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957963", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287ARX9", "url": "https://www.uniprot.org/uniprotkb/A0A287ARX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ARX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ARX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U5M2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U5M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U5Q2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U5Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U9Z9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U9Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UB01", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UB01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UB01-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UB01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QC77", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QC77-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFP5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RF83", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RF83-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RF83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STU6", "url": "https://www.uniprot.org/uniprotkb/F1STU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1STU6-1", "url": "https://www.uniprot.org/uniprotkb/F1STU6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVKKRDTDRALSLLEEYCKKLRKPEEQQLKNAVKKVMGIFKSSLFQALLDIQEFYEVTLLNSQKSCEQKIEEANQVALKWEKTALLAPCHDNLQKSTELTGCSGPKENASCIEQNKDNQCFENESDKKTSQNQGKCPAQNCSVEAPAWMPVHHCTKYRYQDEDAPHDHSLPRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYPHYHLGLLPDSEMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDFILSYEPVARQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "length": 1012, "header": "tr|A0A4X1U5M2-1|A0A4X1U5M2_PIG Isoform 1 of Discs large MAGUK scaffold protein 2 OS=Sus scrofa OX=9823 GN=DLG2 PE=1 SV=1 CANONICAL=A0A4X1U5M2-1" }, "isoforms": [ { "isoform_ac": "A0A287ARX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2/entry#A0A287ARX9-1", "sequence": { "sequence": "MFASIWYAKKLGRRFVHNARKAKSEKASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYPHYHLGLLPDSEMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLKHVSSNASDSESSYRGQEDFILSYEPVARQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "length": 824, "header": "tr|A0A287ARX9-1|A0A4X1U5M2_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 2 OS=Sus scrofa OX=9823 GN=DLG2 PE=1 SV=3 CANONICAL=A0A4X1U5M2-1" }, "locus": { "chromosome": "9", "start_pos": 18495535, "end_pos": 17580797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045223.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045223.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046616.3", "url": "https://www.ensembl.org/id/ENSSSCP00000046616.3" } ] } }, { "isoform_ac": "A0A4X1U5M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2/entry#A0A4X1U5M2-1", "sequence": { "sequence": "MPVKKRDTDRALSLLEEYCKKLRKPEEQQLKNAVKKVMGIFKSSLFQALLDIQEFYEVTLLNSQKSCEQKIEEANQVALKWEKTALLAPCHDNLQKSTELTGCSGPKENASCIEQNKDNQCFENESDKKTSQNQGKCPAQNCSVEAPAWMPVHHCTKYRYQDEDAPHDHSLPRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYPHYHLGLLPDSEMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDFILSYEPVARQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "length": 1012, "header": "tr|A0A4X1U5M2-1|A0A4X1U5M2_PIG Isoform 1 of Discs large MAGUK scaffold protein 2 OS=Sus scrofa OX=9823 GN=DLG2 PE=1 SV=1 CANONICAL=A0A4X1U5M2-1" }, "locus": { "chromosome": "9", "start_pos": 19545717, "end_pos": 17580797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095082.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095082.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080474.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080474.1" } ] } }, { "isoform_ac": "A0A4X1U5Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2/entry#A0A4X1U5Q2-1", "sequence": { "sequence": "MSPVVKDPDCFTPMICHCKVACTNNTLSLMFGCKKYRYQDEDAPHDHSLPRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYPHYHLGLLPDSEMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDFILSYEPVARQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "length": 890, "header": "tr|A0A4X1U5Q2-1|A0A4X1U5Q2_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 2 OS=Sus scrofa OX=9823 GN=DLG2 PE=1 SV=1 CANONICAL=A0A4X1U5M2-1" }, "locus": { "chromosome": "9", "start_pos": 18768310, "end_pos": 17580797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039634.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039634.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045357.3", "url": "https://www.ensembl.org/id/ENSSSCP00000045357.3" } ] } }, { "isoform_ac": "A0A4X1U9Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2/entry#A0A4X1U9Z9-1", "sequence": { "sequence": "MFFACYCALRTNVKKYRYQDEDAPHDHSLPRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYPHYHLGLLPDSEMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLKHVSSNASDSESSYRGQEDFILSYEPVARQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "length": 866, "header": "tr|A0A4X1U9Z9-1|A0A4X1U9Z9_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 2 OS=Sus scrofa OX=9823 GN=DLG2 PE=1 SV=1 CANONICAL=A0A4X1U5M2-1" }, "locus": { "chromosome": "9", "start_pos": 18950626, "end_pos": 17580797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067359.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067359.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066250.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066250.1" } ] } }, { "isoform_ac": "A0A4X1UB01-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2/entry#A0A4X1UB01-1", "sequence": { "sequence": "MQRPSASRAENYQLLWDTIASLKQCEQAMQHAFIPASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYPHYHLGLLPDSEMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLRGQEDFILSYEPVARQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "length": 819, "header": "tr|A0A4X1UB01-1|A0A4X1UB01_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 2 OS=Sus scrofa OX=9823 GN=DLG2 PE=1 SV=1 CANONICAL=A0A4X1U5M2-1" }, "locus": { "chromosome": "9", "start_pos": 18336818, "end_pos": 17580797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078935.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078935.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061778.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061778.1" } ] } }, { "isoform_ac": "A0A5G2QC77-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2/entry#A0A5G2QC77-1", "sequence": { "sequence": "MQRPSASRAENYQLLWDTIASLKQCEQAMQHAFIPASPAPIIVNTDTLDTIPYVTATSFNVYLLFLQGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYPHYHLGLLPDSEMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLKPPWFTNLSRHLHLPLLSAVNYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "length": 818, "header": "tr|A0A5G2QC77-1|A0A4X1U5M2_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 2 OS=Sus scrofa OX=9823 GN=DLG2 PE=1 SV=1 CANONICAL=A0A4X1U5M2-1" }, "locus": { "chromosome": "9", "start_pos": 18336818, "end_pos": 17580797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069995.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069995.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062159.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062159.1" } ] } }, { "isoform_ac": "A0A5G2QFP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2/entry#A0A5G2QFP5-1", "sequence": { "sequence": "MNAYLTKQHSCSRGSDGMDAGRSAPTLIRDAHCACGWQRSPQGLGYNSQTLPPSGPGGPASHRTRLVTLWDNVRKSPHKTGAKGKGTCGERCACPHGWFSPAQASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYPHYHLGLLPDSEMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLKPPWFTNLSRHLHLPLLSAVNYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "length": 889, "header": "tr|A0A5G2QFP5-1|A0A4X1U5M2_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 2 OS=Sus scrofa OX=9823 GN=DLG2 PE=1 SV=2 CANONICAL=A0A4X1U5M2-1" }, "locus": { "chromosome": "9", "start_pos": 18374426, "end_pos": 17580797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084454.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084454.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062580.2", "url": "https://www.ensembl.org/id/ENSSSCP00000062580.2" } ] } }, { "isoform_ac": "A0A5G2QVT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2/entry#A0A5G2QVT7-1", "sequence": { "sequence": "MNAYLTKQHSCSRGSDGMDAGRSAPTLIRDAHCACGWQRSPQGLGYNSQTLPPSGPGGPASHRTRLVTLWDNVRKSPHKTGAKGKGTCGERCACPHGWFSPAQASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVEDDYTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLKPPWFTNLSRHLHLPLLSAVNYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "length": 837, "header": "tr|A0A5G2QVT7-1|A0A4X1U5M2_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 2 OS=Sus scrofa OX=9823 GN=DLG2 PE=1 SV=2 CANONICAL=A0A4X1U5M2-1" }, "locus": { "chromosome": "9", "start_pos": 18374426, "end_pos": 17580797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087585.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087585.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068260.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068260.2" } ] } }, { "isoform_ac": "A0A5G2RF83-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2/entry#A0A5G2RF83-1", "sequence": { "sequence": "MNAYLTKQHSCSRGSDGMDAGRSAPTLIRDAHCACGWQRSPQGLGYNSQTLPPSGPGGPASHRTRLVTLWDNVRKSPHKTGAKGKGTCGERCACPHGWFSPAQASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYPHYHLGLLPDSEMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLRGQEDFILSYEPVARQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "length": 887, "header": "tr|A0A5G2RF83-1|A0A4X1U5M2_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 2 OS=Sus scrofa OX=9823 GN=DLG2 PE=1 SV=1 CANONICAL=A0A4X1U5M2-1" }, "locus": { "chromosome": "9", "start_pos": 18374426, "end_pos": 17580797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077391.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077391.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069638.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069638.1" } ] } }, { "isoform_ac": "F1STU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2/entry#F1STU6-1", "sequence": { "sequence": "SPCLSHCTNLHLPLHSASPAPIIVNTDTLDTIPYVTATSFNVYLLFLQGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYPHYHLGLLPDSEMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDFILSYEPVARQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "length": 815, "header": "tr|F1STU6-1|A0A4X1U5M2_PIG Computationally mapped isoform of Discs large MAGUK scaffold protein 2 OS=Sus scrofa OX=9823 GN=DLG2 PE=1 SV=4 CANONICAL=A0A4X1U5M2-1" }, "locus": { "chromosome": "9", "start_pos": 18315605, "end_pos": 17580797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016259.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016259.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015825.5", "url": "https://www.ensembl.org/id/ENSSSCP00000015825.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QC77", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC77" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5M2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5M2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5M2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5M2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5M2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5M2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 663, "end_pos": 665, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U5M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2" }, { "id": "PS50052", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50052" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate kinase-like", "eco_id": "ECO_0000259", "start_pos": 822, "end_pos": 997, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1U5M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2" }, { "id": "PS51022", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L27", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 64, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1U5M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 240, "end_pos": 327, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1U5M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5M2" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 678, "end_pos": 748, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 124, "end_pos": 126 }, { "start_pos": 141, "end_pos": 143 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 409, "end_pos": 411 }, { "start_pos": 452, "end_pos": 454 }, { "start_pos": 663, "end_pos": 665 }, { "start_pos": 714, "end_pos": 716 }, { "start_pos": 820, "end_pos": 822 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VUZ6-1", "uniprot_ac": "A0A4X1VUZ6", "uniprot_id": "A0A4X1VUZ6_PIG", "mass": { "chemical_mass": 49613.0, "monoisotopic_mass": 49613.0 }, "refseq": { "ac": "XP_020941331", "name": "clusterin-associated protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941331" }, "gene_names": [ { "name": "CLUAP1", "type": "recommended", "evidence": [ { "id": "A0A4X1VUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6" } ] }, { "name": "CLUAP1", "type": "synonym", "evidence": [ { "id": "XP_020941331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941331" } ] } ], "protein_names": [ { "name": "Clusterin associated protein 1", "type": "synonym", "evidence": [ { "id": "A0A4X1VUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6/entry#names_and_taxonomy" } ] }, { "name": "clusterin-associated protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020941331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941331" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VUZ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CLUAP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6", "locus": { "chromosome": "3", "start_pos": 38716431, "end_pos": 38753748, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007955", "url": "https://www.ensembl.org/id/ENSSSCG00000007955" } ] } } ], "crossref": [ { "id": "A0A4X1VUZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1VUZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000007955", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007955", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100514829", "url": "https://www.ncbi.nlm.nih.gov/gene/100514829", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1VUZ6", "url": "https://www.orthodb.org/?gene=A0A4X1VUZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21547", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21547", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21547:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21547:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020941331", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941331", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AY82", "url": "https://www.uniprot.org/uniprotkb/A0A287AY82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AY82-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AY82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VUZ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VUZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFRDLRNFTEMMRALGYPRHISMENFRTPNFDLVSEVLLWLVKRYEPQTDIPSDVDTEQDRVFFIKAVAQFMATKAHIKLNTKKLYQADGYAVKELLKIASVLYSAMTTKGLEGSSLGQGDVSKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGKEVELRELRTEAIARPLEINEIEKVMRIAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKIEEELQKQYAIYLEKFRNLACLEQQLEDHHRMEQERFEEAENTLRLMQNKLKEEEKRLLKSGSHDDSDMDIQEDNESDSELEARRLSKPWTAVEVLMQGRASKRIVGTMQGADSDDDMEAAPALLGKCKTSSSRKQEDSEDSEIDLEDEEDDDDDLEDESIAVSPAKPSRRGRKPEPLDESDNDF", "length": 432, "header": "tr|A0A4X1VUZ6-1|A0A4X1VUZ6_PIG Isoform 1 of Clusterin associated protein 1 OS=Sus scrofa OX=9823 GN=CLUAP1 PE=3 SV=1 CANONICAL=A0A4X1VUZ6-1" }, "isoforms": [ { "isoform_ac": "A0A287AY82-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6/entry#A0A287AY82-1", "sequence": { "sequence": "MSFRDLRNFTEMMRALGYPRHISMENFRTPNFDLVSEVLLWLVKRYEPQTDIPSDVDTEQDRVFFIKAVAQFMATKAHIKLNTKKLYQADGYAVKELLKIASVLYSAMTTKGLEGSSLGQGDVSKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGKEVELRELRTEAIARPLEINEIEKVMRIAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKIEEELQKQYAIYLEKFRNLACLEQQLEDHHRMEQERFEEAENTLRLMQNKLKEEEKRLLKSGSHDDSDMDIQEDNESDSELEARRLSKPWTAVEVLMQGRASKRIVGTMQGADSDDDVSSPSSLSAPLSAVLGWPHGRGWPGS", "length": 390, "header": "tr|A0A287AY82-1|A0A4X1VUZ6_PIG Computationally mapped isoform of Clusterin associated protein 1 OS=Sus scrofa OX=9823 GN=CLUAP1 PE=3 SV=2 CANONICAL=A0A4X1VUZ6-1" }, "locus": { "chromosome": "3", "start_pos": 38753317, "end_pos": 38721745, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053266.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053266.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048906.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048906.2" } ] } }, { "isoform_ac": "A0A4X1VUZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6/entry#A0A4X1VUZ6-1", "sequence": { "sequence": "MSFRDLRNFTEMMRALGYPRHISMENFRTPNFDLVSEVLLWLVKRYEPQTDIPSDVDTEQDRVFFIKAVAQFMATKAHIKLNTKKLYQADGYAVKELLKIASVLYSAMTTKGLEGSSLGQGDVSKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGKEVELRELRTEAIARPLEINEIEKVMRIAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKIEEELQKQYAIYLEKFRNLACLEQQLEDHHRMEQERFEEAENTLRLMQNKLKEEEKRLLKSGSHDDSDMDIQEDNESDSELEARRLSKPWTAVEVLMQGRASKRIVGTMQGADSDDDMEAAPALLGKCKTSSSRKQEDSEDSEIDLEDEEDDDDDLEDESIAVSPAKPSRRGRKPEPLDESDNDF", "length": 432, "header": "tr|A0A4X1VUZ6-1|A0A4X1VUZ6_PIG Isoform 1 of Clusterin associated protein 1 OS=Sus scrofa OX=9823 GN=CLUAP1 PE=3 SV=1 CANONICAL=A0A4X1VUZ6-1" }, "locus": { "chromosome": "3", "start_pos": 38753317, "end_pos": 38718377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040483.2", "url": "https://www.ensembl.org/id/ENSSSCT00000040483.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041705.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041705.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AY82", "url": "https://www.uniprot.org/uniprotkb/A0A287AY82" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620924", "resource": "Reactome", "description": "Intraflagellar transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VUZ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VUZ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VUZ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VUZ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VUZ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6" } ], "pmid": "" }, { "name": "intraciliary transport particle A", "id": "GO:0030991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030991", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VUZ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6" } ], "pmid": "" }, { "name": "intraciliary transport particle B", "id": "GO:0030992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VUZ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6" } ], "pmid": "" }, { "name": "ciliary tip", "id": "GO:0097542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097542", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VUZ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VUZ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VUZ6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VUZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 322, "end_pos": 324 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1VGU0-1", "uniprot_ac": "A0A4X1VGU0", "uniprot_id": "A0A4X1VGU0_PIG", "mass": { "chemical_mass": 83987.0, "monoisotopic_mass": 83987.0 }, "refseq": {}, "gene_names": [ { "name": "KIRREL3", "type": "recommended", "evidence": [ { "id": "A0A4X1VGU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ] } ], "protein_names": [ { "name": "Kirre like nephrin family adhesion molecule 3", "type": "synonym", "evidence": [ { "id": "A0A4X1VGU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KIRREL3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0", "locus": { "chromosome": "9", "start_pos": 53491991, "end_pos": 53664072, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015234", "url": "https://www.ensembl.org/id/ENSSSCG00000015234" } ] } } ], "crossref": [ { "id": "A0A4X1VGU0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1VGU0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015234", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015234", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05759", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05759", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05898", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05898", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11640", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11640", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11640:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11640:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-373753", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-373753", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BIQ0", "url": "https://www.uniprot.org/uniprotkb/A0A287BIQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BIQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VGU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKDKFRRMNEGQVYSFSQQPQDQAVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNISRTVDVYFGPRMTTEPQSLLVDLGSDAVFSCAWTGNPSLTIVWMKRGSGVVLSNEKTLTLKTVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETVSTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLLATIVAFCCARSQRSTGGRAGSSGRGTEKKARLRLPRRANLKGVVSAKNDIRVEIVHKEPASGREAEEHPTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTPTISLSSCQPDLRPAGKQRVPTGMSFTNIYSTLSGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSSHHSQSSSQNSDPSRPLQRRMQTHV", "length": 770, "header": "tr|A0A4X1VGU0-1|A0A4X1VGU0_PIG Isoform 1 of Kirre like nephrin family adhesion molecule 3 OS=Sus scrofa OX=9823 GN=KIRREL3 PE=3 SV=1 CANONICAL=A0A4X1VGU0-1" }, "isoforms": [ { "isoform_ac": "A0A287BIQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0/entry#A0A287BIQ0-1", "sequence": { "sequence": "MNGIAGGQRRMDGAGRRRPELGLQKRGCCLVLGYMAKDKFRRMNEGQVYSFSQQPQDQAVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNISRTVDVYFGPRMTTEPQSLLVDLGSDAVFSCAWTGNPSLTIVWMKRGSGVVLSNEKTLTLKTVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETVSTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQESVPMAVIIGVAVGAGVAFLVLLATIVAFCCARSQRNLKGVVSAKNDIRVEIVHKEPASGREAEEHPTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTPTISLSSCQPDLRPAGKQRVPTGMSFTNIYSTLSGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSSHHSQSSSQNSDPSRPLQRRMQTHV", "length": 767, "header": "tr|A0A287BIQ0-1|A0A287BIQ0_PIG Computationally mapped isoform of Kirre like nephrin family adhesion molecule 3 OS=Sus scrofa OX=9823 GN=KIRREL3 PE=3 SV=2 CANONICAL=A0A4X1VGU0-1" }, "locus": { "chromosome": "9", "start_pos": 53663784, "end_pos": 53494551, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050766.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050766.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056014.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056014.2" } ] } }, { "isoform_ac": "A0A4X1VGU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0/entry#A0A4X1VGU0-1", "sequence": { "sequence": "MAKDKFRRMNEGQVYSFSQQPQDQAVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNISRTVDVYFGPRMTTEPQSLLVDLGSDAVFSCAWTGNPSLTIVWMKRGSGVVLSNEKTLTLKTVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETVSTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLLATIVAFCCARSQRSTGGRAGSSGRGTEKKARLRLPRRANLKGVVSAKNDIRVEIVHKEPASGREAEEHPTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTPTISLSSCQPDLRPAGKQRVPTGMSFTNIYSTLSGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSSHHSQSSSQNSDPSRPLQRRMQTHV", "length": 770, "header": "tr|A0A4X1VGU0-1|A0A4X1VGU0_PIG Isoform 1 of Kirre like nephrin family adhesion molecule 3 OS=Sus scrofa OX=9823 GN=KIRREL3 PE=3 SV=1 CANONICAL=A0A4X1VGU0-1" }, "locus": { "chromosome": "9", "start_pos": 53621545, "end_pos": 53494551, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016600.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016600.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016155.5", "url": "https://www.ensembl.org/id/ENSSSCP00000016155.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-373753", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-373753", "resource": "Reactome", "description": "Nephrin family interactions" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "pmid": "" }, { "name": "dendritic shaft", "id": "GO:0043198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043198", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "hippocampus development", "id": "GO:0021766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021766", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGU0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1VGU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGU0" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 109, "start_aa": "Tyr", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 465, "end_pos": 467 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1V4T2-1", "uniprot_ac": "A0A4X1V4T2", "uniprot_id": "A0A4X1V4T2_PIG", "mass": { "chemical_mass": 56016.0, "monoisotopic_mass": 56016.0 }, "refseq": { "ac": "NP_001231585", "name": "zinc finger protein 639", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231585" }, "gene_names": [ { "name": "ZNF639", "type": "recommended", "evidence": [ { "id": "A0A4X1V4T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ] }, { "name": "ZNF639", "type": "synonym", "evidence": [ { "id": "NP_001231585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231585" } ] } ], "protein_names": [ { "name": "Zinc finger protein 639", "type": "recommended", "evidence": [ { "id": "A0A4X1V4T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 639", "type": "synonym", "evidence": [ { "id": "NP_001231585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231585" } ] } ], "function": [ { "annotation": "Binds DNA and may function as a transcriptional repressor.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BP60", "url": "https://www.uniprot.org/uniprotkb/A0A287BP60#function" }, { "database": "UniProtKB", "id": "ARBA00059986", "url": "https://www.uniprot.org/uniprotkb/ARBA00059986#function" }, { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF639", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2", "locus": { "chromosome": "13", "start_pos": 117384041, "end_pos": 117370544, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000038443", "url": "https://www.ensembl.org/id/ENSSSCG00000038443" } ] } } ], "crossref": [ { "id": "A0A4X1V4T2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1V4T2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000038443", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000038443", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100623119", "url": "https://www.ncbi.nlm.nih.gov/gene/100623119", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623119", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623119", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDINRGR", "url": "https://omabrowser.org/oma/group/PDINRGR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1V4T2", "url": "https://www.orthodb.org/?gene=A0A4X1V4T2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231585", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BP60", "url": "https://www.uniprot.org/uniprotkb/A0A287BP60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BP60-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BP60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V4T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEYPKKRKRKTLHPSRYSDSSGISRIADGFNGIFSDHCYSVCSMRQPDLKYFDNKDDDSDTETSNDLPKFTDGIKARNRNQNYLVPSPVLRILDHTAFSTEKSADIEICDEECDSPESVNQQTQEESAIEVHTAEDVPIAAEVHAISEDYDIEAENNSSESLQDQTDEEPPAKLCKILDKSQALNVTAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHMILKHKRTDSNVCRVCKESFSTNMLLIEHAKLHEEDPYICKYCDYKTVIFENLSQHIADTHFSDHLYWCEQCDVQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACKLIELSDKYNNGEHGQYSLLSKITFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSSMLEYCKHLNSHLSEGIYLCQYCEYSTGQIEDLKIHLDFKHSADLPHKCSDCLMRFGNERELISHLPVHETS", "length": 485, "header": "tr|A0A4X1V4T2-1|A0A4X1V4T2_PIG Isoform 1 of Zinc finger protein 639 OS=Sus scrofa OX=9823 GN=ZNF639 PE=3 SV=1 CANONICAL=A0A4X1V4T2-1" }, "isoforms": [ { "isoform_ac": "A0A287BP60-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2/entry#A0A287BP60-1", "sequence": { "sequence": "MNEYPKKRKRKTLHPSRYSDSSGISRIADGFNGIFSDHCYSVCSMRQPDLKYFDNKDGIKARNRNQNYLVPSPVLRILDHTAFSTEKSADIEICDEECDSPESVNQQTQEESAIEVHTAEDVPIAAEVHAISEDYDIEAENNSSESLQDQTDEEPPAKLCKILDKSQALNVTAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHMILKHKRTDSNVCRVCKESFSTNMLLIEHAKLHEEDPYICKYCDYKTVIFENLSQHIADTHFSDHLYWCEQCDVQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACKLIELSDKYNNGEHGQYSLLSKITFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSSMLEYCKHLNSHLSEGIYLCQYCEYSTGQIEDLKIHLDFKHSADLPHKCSDCLMRFGNERELISHLPVHETS", "length": 469, "header": "tr|A0A287BP60-1|A0A287BP60_PIG Computationally mapped isoform of Zinc finger protein 639 OS=Sus scrofa OX=9823 GN=ZNF639 PE=3 SV=2 CANONICAL=A0A4X1V4T2-1" }, "locus": { "chromosome": "13", "start_pos": 117383693, "end_pos": 117375722, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060729.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060729.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057966.2", "url": "https://www.ensembl.org/id/ENSSSCP00000057966.2" } ] } }, { "isoform_ac": "A0A4X1V4T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2/entry#A0A4X1V4T2-1", "sequence": { "sequence": "MNEYPKKRKRKTLHPSRYSDSSGISRIADGFNGIFSDHCYSVCSMRQPDLKYFDNKDDDSDTETSNDLPKFTDGIKARNRNQNYLVPSPVLRILDHTAFSTEKSADIEICDEECDSPESVNQQTQEESAIEVHTAEDVPIAAEVHAISEDYDIEAENNSSESLQDQTDEEPPAKLCKILDKSQALNVTAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHMILKHKRTDSNVCRVCKESFSTNMLLIEHAKLHEEDPYICKYCDYKTVIFENLSQHIADTHFSDHLYWCEQCDVQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACKLIELSDKYNNGEHGQYSLLSKITFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSSMLEYCKHLNSHLSEGIYLCQYCEYSTGQIEDLKIHLDFKHSADLPHKCSDCLMRFGNERELISHLPVHETS", "length": 485, "header": "tr|A0A4X1V4T2-1|A0A4X1V4T2_PIG Isoform 1 of Zinc finger protein 639 OS=Sus scrofa OX=9823 GN=ZNF639 PE=3 SV=1 CANONICAL=A0A4X1V4T2-1" }, "locus": { "chromosome": "13", "start_pos": 117383693, "end_pos": 117375722, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093819.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093819.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080296.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080296.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623119", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623119", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z525-1", "protein_name": "Zinc finger protein 639", "gene_name": "ZNF639", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNEHPKKRKRKTLHPSRYSDSSGAPKYIDNSGIFSDHCYSVCSMKQPDIKYSENRGRYHSPVQSIDTDDDGSPVHAGTSQWSGSHSNIGLHYTDPKKKDKDKAANNGTCKDVCDSPIFSDSPTEEEKPLDIQTVEISTTEVNAVEVHDIETQTVSPEKLEAEDLEEIPLETCKIFEKNQALNITAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHMILKHKTCADTHVCKVCKESFSSKVQLIEHVKLHEEDPYICKYCDYKTVIFENLSQHIADTHFNDHLYWCEQCDMQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACRLIELSDSYHNKERGQYSLINKISFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSGMLEYCKHLSSHLSEGIYLCQYCEYSTGQIEDLKTHLDFRHSTDLPHKCTDCLMRFGNEKDLLSHLQIHETA", "length": 482 }, "evidence": [ { "id": "A0A4X1V4T2", "url": "https://omabrowser.org/oma/group/A0A4X1V4T2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A5PK30-1", "protein_name": "Zinc finger protein 639", "gene_name": "ZNF639", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNEYPKKRKRKTLHPSRYSDSSGISRIADGFNGIFSDHCYSVCSMRQPDLKYFDNKDDDSDTETSNELPKFTDGIKARNRNQNYLVPSPVLRILDHTAFPTEKSADIEICDEDCDSPESVHQQTQEESPIEVHTAEDVPIAAEVHAISEDYDIETENNSSESLQDQTDEEPPAKLCKIVDKSQALNVTAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHMILKHKRTDSNVCRVCKESFSTNMLLIEHAKLHEEDPYICKYCDYKTVIFENLSQHIADTHFSDHLYWCEQCDVQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACKLIELSDKYNNGEHGQYSLLSKITFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSSMLEYCKHLNSHLSEGIYLCQYCEYSTGQIEDLKIHLDFKHSADLPHKCSDCLMRFGNERELISHLPVHETT", "length": 485 }, "evidence": [ { "id": "A0A4X1V4T2", "url": "https://omabrowser.org/oma/group/A0A4X1V4T2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99KZ6-1", "protein_name": "Zinc finger protein 639", "gene_name": "Znf639", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNEYPKKRKRKTLHPSRYSDSSGISRIADGVSGIFSDHCYSVCSMRQPDLKYFDNKDDDSDPETANDLPKFADGTKARNRNQSYLVPSPVLRILDHTVFSTEKSTEVEICDEECASPESVHQHTQEESPIEVHTSEDVPIAVEVHAISEDYDIEAENNSSESLQDQADEEPPAKLCKILDKGQALNVTAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHVILKHKRTDSNVCRVCKESFSTNMLLIEHAKLHEEDPYICKYCDYKTVIFENLSQHIADTHFSDHLYWCEQCDVQFSSSSELYLHFQEHSRDEQYLCQFCEHETGDPEDLHSHVVNEHARRLIELSDKCGSGGHGQCSLLSKITFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSSMLEYCKHLNSHLSEGIYLCQYCEYSTGQIDDLKIHLDFKHSADLPHKCSECLMRFGNERDLLGHLQVHETT", "length": 485 }, "evidence": [ { "id": "A0A4X1V4T2", "url": "https://omabrowser.org/oma/group/A0A4X1V4T2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UID6-1", "protein_name": "Zinc finger protein 639", "gene_name": "ZNF639", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNEYPKKRKRKTLHPSRYSDSSGISRIADGFNGIFSDHCYSVCSMRQPDLKYFDNKDDDSDTETSNDLPKFADGIKARNRNQNYLVPSPVLRILDHTAFSTEKSADIVICDEECDSPESVNQQTQEESPIEVHTAEDVPIAVEVHAISEDYDIETENNSSESLQDQTDEEPPAKLCKILDKSQALNVTAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHMILKHKRTDSNVCRVCKESFSTNMLLIEHAKLHEEDPYICKYCDYKTVIFENLSQHIADTHFSDHLYWCEQCDVQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACKLIELSDKYNNGEHGQYSLLSKITFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSSMLEYCKHLNSHLSEGIYLCQYCEYSTGQIEDLKIHLDFKHSADLPHKCSDCLMRFGNERELISHLPVHETT", "length": 485 }, "evidence": [ { "id": "A0A4X1V4T2", "url": "https://omabrowser.org/oma/group/A0A4X1V4T2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" }, { "name": "symbiont entry into host cell", "id": "GO:0046718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046718", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" }, { "name": "host-mediated suppression of viral transcription", "id": "GO:0043922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043922", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" }, { "name": "host-mediated activation of viral transcription", "id": "GO:0043923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043923", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V4T2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1V4T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V4T2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 233, "end_pos": 260, "start_aa": "Asn", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 158, "end_pos": 160 }, { "start_pos": 186, "end_pos": 188 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 274, "end_pos": 276 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TRK5-1", "uniprot_ac": "A0A4X1TRK5", "uniprot_id": "A0A4X1TRK5_PIG", "mass": { "chemical_mass": 20905.0, "monoisotopic_mass": 20905.0 }, "refseq": { "ac": "XP_020923135", "name": "transmembrane protein 97", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020923135" }, "gene_names": [ { "name": "TMEM97", "type": "recommended", "evidence": [ { "id": "A0A4X1TRK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ] }, { "name": "TMEM97", "type": "synonym", "evidence": [ { "id": "XP_020923135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020923135" } ] } ], "protein_names": [ { "name": "Transmembrane protein 97", "type": "recommended", "evidence": [ { "id": "A0A4X1TRK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 97", "type": "synonym", "evidence": [ { "id": "XP_020923135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020923135" } ] } ], "function": [ { "annotation": "Sigma-2 receptor which contributes to ameliorate dysfunctional cellular processes and slow degenerative progression by regulating cell functions including cholesterol biosynthesis/trafficking, membrane trafficking, autophagy, lipid membrane-bound protein trafficking, and receptor stabilization at the cell surface. Forms a ternary complex with PGRMC1 receptor and low density lipoprotein receptor/LDLR at the plasma membrane, which increases LDLR-mediated LDL cholesterol internalization. Decreases lysosomal sterol transporter NPC1 availability to the cell, probably through NPC1-binding, hence controlling lipid transport, including cholesterol and LBPA, outside of late endosome/lysosome. Binds regio- and stereoselective ligand 20(S)-hydroxycholesterol (20(S)-OHC), thereby linking OHC binding to cholesterol homeostasis. Also able to bind cholesterol. Binds histatin 1 (Hst 1)/HN1 salivary peptide at the ER membrane, which is critical for increasing mitochondria-ER contacts and stimulating Hst1 wound healing properties. May alter the activity of some cytochrome P450 proteins. Although shows homologies with sterol isomerases (EXPERA domain), not able to catalyze sterol isomerization. However, may act as sensors of these molecules. Acts as a quality control factor in the ER, promoting the proteolytic degradation of nonproductive and extramitochondrial precursor proteins in the ER membrane thus removing them from the ER surface.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5#function" }, { "database": "UniProtKB", "id": "PIRNR031032", "url": "https://www.uniprot.org/uniprotkb/PIRNR031032#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMEM97", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5", "locus": { "chromosome": "12", "start_pos": 44609999, "end_pos": 44604021, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000033123", "url": "https://www.ensembl.org/id/ENSSSCG00000033123" } ] } } ], "crossref": [ { "id": "A0A4X1TRK5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TRK5", "database": "AlphaFoldDB", "categories": [] }, { "id": "110256064", "url": "https://www.ncbi.nlm.nih.gov/gene/110256064", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033118", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033118", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110256064", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110256064", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EFKDPMV", "url": "https://omabrowser.org/oma/group/EFKDPMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TRK5", "url": "https://www.orthodb.org/?gene=A0A4X1TRK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31204", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31204", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31204:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31204:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020923135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020923135", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TRK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFF2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMGRLGVRRGLEWLLGFYFLSHIPLTLLVDMQALLPPDLYPVELRNLCKWYTQEFKDTLLQSPPAWFKAFLFCELVFQLPFFPFATYAFFKGGCKWIRTPAIIYSVHTMTTLIPIVSTFLFEDFSKASCFKGQGPTTFHERLLLLSVYIPYFLIPLMLLLFMLRNPYYKSEEKRKKK", "length": 177, "header": "tr|A0A4X1TRK5-1|A0A4X1TRK5_PIG Isoform 1 of Transmembrane protein 97 OS=Sus scrofa OX=9823 GN=TMEM97 PE=3 SV=1 CANONICAL=A0A4X1TRK5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TRK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5/entry#A0A4X1TRK5-1", "sequence": { "sequence": "MMGRLGVRRGLEWLLGFYFLSHIPLTLLVDMQALLPPDLYPVELRNLCKWYTQEFKDTLLQSPPAWFKAFLFCELVFQLPFFPFATYAFFKGGCKWIRTPAIIYSVHTMTTLIPIVSTFLFEDFSKASCFKGQGPTTFHERLLLLSVYIPYFLIPLMLLLFMLRNPYYKSEEKRKKK", "length": 177, "header": "tr|A0A4X1TRK5-1|A0A4X1TRK5_PIG Isoform 1 of Transmembrane protein 97 OS=Sus scrofa OX=9823 GN=TMEM97 PE=3 SV=1 CANONICAL=A0A4X1TRK5-1" }, "locus": { "chromosome": "12", "start_pos": 44608402, "end_pos": 44604178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025956.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025956.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027559.2", "url": "https://www.ensembl.org/id/ENSSSCP00000027559.2" } ] } }, { "isoform_ac": "A0A8W4FFF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5/entry#A0A8W4FFF2-1", "sequence": { "sequence": "MGRLGVRRGLEWLLGFYFLSHIPLTLLVDMQALLPPDLYPVELRNLCKWYTQEFKDTLLQSPPAWFKAFLFCELVFQLPFFPFATYAFFKG", "length": 91, "header": "tr|A0A8W4FFF2-1|A0A4X1TRK5_PIG Computationally mapped isoform of Transmembrane protein 97 OS=Sus scrofa OX=9823 GN=TMEM97 PE=3 SV=1 CANONICAL=A0A4X1TRK5-1" }, "locus": { "chromosome": "12", "start_pos": 44607494, "end_pos": 44604181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105179.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105179.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077041.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077041.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FFF2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFF2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110256064", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110256064", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N859-1", "protein_name": "Transmembrane protein 97", "gene_name": "TMEM97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARALRCLEAAFALYFVSHIPITLLLDLQALLPAGLHPQQLTELLRWYATTFRDPMMLHPPEWFKAFIYCEAALQLPFFPVAAYAFLKGGCKWIRTPAIIYSTHVATTLFAILAHILFHDFSASEHLGPQTLRERLILLSVYAPYLLIPLLILFTMLYSPQYNQVEKRKRR", "length": 171 }, "evidence": [ { "id": "A0A4X1TRK5", "url": "https://omabrowser.org/oma/group/A0A4X1TRK5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q3MHW7-1", "protein_name": "Sigma intracellular receptor 2", "gene_name": "TMEM97", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGTLGARRGLEWFLGFYFLSHIPITLLMDLQGVLPRDLYPVELRNLQQWYIEEFKDPLLQTPPAWFKSFLFCELVFQLPFFPIAAYAFFKGGCKWIRTPAIIYSVHTMTTLIPILSTLLLDDFSKASHFRGQGPKTFQERLFLISVYIPYFLIPLILLLFMVRNPYYKSEEKRKKK", "length": 176 }, "evidence": [ { "id": "A0A4X1TRK5", "url": "https://omabrowser.org/oma/group/A0A4X1TRK5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5BJF2-1", "protein_name": "Sigma intracellular receptor 2", "gene_name": "TMEM97", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK", "length": 176 }, "evidence": [ { "id": "A0A4X1TRK5", "url": "https://omabrowser.org/oma/group/A0A4X1TRK5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VD00-1", "protein_name": "Sigma intracellular receptor 2", "gene_name": "Tmem97", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGALAARRCVEWLLGLYFVSHIPITLFIDLQAVLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLLCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAAHTITTLIPILYTLLFEDFSKAVAFKGQRPESFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKYEEKRKKK", "length": 176 }, "evidence": [ { "id": "A0A4X1TRK5", "url": "https://omabrowser.org/oma/group/A0A4X1TRK5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxysterol binding", "id": "GO:0008142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008142", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum membrane", "id": "GO:0030867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030867", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of intracellular cholesterol transport", "id": "GO:0032383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032383", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ], "pmid": "" }, { "name": "positive regulation of wound healing", "id": "GO:0090303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090303", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ], "pmid": "" }, { "name": "positive regulation of lipoprotein transport", "id": "GO:0140077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140077", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRK5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TRK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRK5" }, { "id": "PS51751", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51751" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EXPERA", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 159, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TWN6-1", "uniprot_ac": "A0A4X1TWN6", "uniprot_id": "A0A4X1TWN6_PIG", "mass": { "chemical_mass": 51664.0, "monoisotopic_mass": 51664.0 }, "refseq": { "ac": "XP_005654535", "name": "protein disulfide-isomerase TMX3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654535" }, "gene_names": [ { "name": "TMX3", "type": "recommended", "evidence": [ { "id": "A0A4X1TWN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6" } ] }, { "name": "TMX3", "type": "synonym", "evidence": [ { "id": "XP_005654535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654535" } ] } ], "protein_names": [ { "name": "Protein disulfide-isomerase TMX3", "type": "recommended", "evidence": [ { "id": "A0A4X1TWN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6/entry#names_and_taxonomy" } ] }, { "name": "5.3.4.1", "type": "synonym", "evidence": [ { "id": "A0A4X1TWN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6/entry#names_and_taxonomy" } ] }, { "name": "Thioredoxin domain-containing protein 10", "type": "synonym", "evidence": [ { "id": "A0A4X1TWN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6/entry#names_and_taxonomy" } ] }, { "name": "Thioredoxin-related transmembrane protein 3", "type": "synonym", "evidence": [ { "id": "A0A4X1TWN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6/entry#names_and_taxonomy" } ] }, { "name": "protein disulfide-isomerase TMX3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005654535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654535" } ] } ], "function": [ { "annotation": "Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase. Acts as a regulator of endoplasmic reticulum-mitochondria contact sites via its ability to regulate redox signals.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6#function" }, { "database": "UniProtKB", "id": "ARBA00045246", "url": "https://www.uniprot.org/uniprotkb/ARBA00045246#function" }, { "database": "UniProtKB", "id": "A0A4X1TRP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRP3#function" }, { "database": "UniProtKB", "id": "F1SMY1", "url": "https://www.uniprot.org/uniprotkb/F1SMY1#function" }, { "database": "UniProtKB", "id": "A0A8D0WDN6", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WDN6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMX3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6", "locus": { "chromosome": "1", "start_pos": 154031120, "end_pos": 153988050, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004884", "url": "https://www.ensembl.org/id/ENSSSCG00000004884" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004884", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004884", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03000", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03000", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100518050", "url": "https://www.ncbi.nlm.nih.gov/gene/100518050", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518050", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518050", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GIEMRNM", "url": "https://omabrowser.org/oma/group/GIEMRNM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TWN6", "url": "https://www.orthodb.org/?gene=A0A4X1TWN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46426", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46426", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46426:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46426:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13848", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13848", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005654535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654535", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TRP3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TRP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TTV2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TTV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TWN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TWN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0WDN6", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WDN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0WDN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WDN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJ21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJ21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJ21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SMY1", "url": "https://www.uniprot.org/uniprotkb/F1SMY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SMY1-1", "url": "https://www.uniprot.org/uniprotkb/F1SMY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARSRGAALGLCATVFLLDVAFCKGFVEDLDESFKDNRKDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHVQKRHRVFFVYIGGESPLKEKYIDAASELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLTMDGFLLYELGDTGKLVAIAVVDEKNTSIEHTRLKSVIQEVARDYRDQFHRDFQFGHMDGNEYINTLLMDELKVPTVVVLNTSNQQYFLLDRQIKNAEDMVQFINNILDGTVNAQGGDSIVQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSETESPEPVEESKEQQEPRSGDPLVPAVQEPKDVLEKKKD", "length": 454, "header": "tr|A0A4X1TWN6-1|A0A4X1TWN6_PIG Isoform 1 of Protein disulfide-isomerase TMX3 OS=Sus scrofa OX=9823 GN=TMX3 PE=1 SV=1 CANONICAL=A0A4X1TWN6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TRP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6/entry#A0A4X1TRP3-1", "sequence": { "sequence": "MAARSRGAALGLCATVFLLDVAFCKGFVEDLDESFKDNRKDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLALIRPLPSQQMFEHVQKRHRVFFVYIGGESPLKEKYIDAASELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDGKFQSFNHKTL", "length": 196, "header": "tr|A0A4X1TRP3-1|A0A4X1TRP3_PIG Computationally mapped isoform of protein disulfide-isomerase OS=Sus scrofa OX=9823 GN=TMX3 PE=1 SV=1 CANONICAL=A0A4X1TWN6-1" }, "locus": { "chromosome": "1", "start_pos": 154010501, "end_pos": 153988237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080625.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080625.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062793.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062793.1" } ] } }, { "isoform_ac": "A0A4X1TTV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6/entry#A0A4X1TTV2-1", "sequence": { "sequence": "MAARSRGAALGLCATVFLLDVAFCKGFVEDLDESIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHVQKRHRVFFVYIGGESPLKEKYIDAASELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLTMDGFLLYELGDTGKLVAIAVVDEKNTSIEHTRLKSVIQEVARDYRDQFHRDFQFGHMDGNEYINTLLMDELKVPTVVVLNTSNQQYFLLDRQIKNAEDMVQFINNILDGTVNAQGGDSIVQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSETESPEPVEESKEQQEPRSGDPLVPAVQEPKDVLEKKKD", "length": 416, "header": "tr|A0A4X1TTV2-1|A0A4X1TTV2_PIG Computationally mapped isoform of protein disulfide-isomerase OS=Sus scrofa OX=9823 GN=TMX3 PE=1 SV=1 CANONICAL=A0A4X1TWN6-1" }, "locus": { "chromosome": "1", "start_pos": 154027911, "end_pos": 153988237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077178.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077178.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059657.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059657.1" } ] } }, { "isoform_ac": "A0A4X1TWN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6/entry#A0A4X1TWN6-1", "sequence": { "sequence": "MAARSRGAALGLCATVFLLDVAFCKGFVEDLDESFKDNRKDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHVQKRHRVFFVYIGGESPLKEKYIDAASELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLTMDGFLLYELGDTGKLVAIAVVDEKNTSIEHTRLKSVIQEVARDYRDQFHRDFQFGHMDGNEYINTLLMDELKVPTVVVLNTSNQQYFLLDRQIKNAEDMVQFINNILDGTVNAQGGDSIVQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSETESPEPVEESKEQQEPRSGDPLVPAVQEPKDVLEKKKD", "length": 454, "header": "tr|A0A4X1TWN6-1|A0A4X1TWN6_PIG Isoform 1 of Protein disulfide-isomerase TMX3 OS=Sus scrofa OX=9823 GN=TMX3 PE=1 SV=1 CANONICAL=A0A4X1TWN6-1" }, "locus": { "chromosome": "1", "start_pos": 154027911, "end_pos": 153988237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078697.1", "url": "https://www.ensembl.org/id/ENSSSCT00000078697.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070070.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070070.1" } ] } }, { "isoform_ac": "A0A8D0WDN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6/entry#A0A8D0WDN6-1", "sequence": { "sequence": "MAARSRGAALGLCATVFLLDVAFCKGFVEDLDESFKDNRKDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHVQKRHRVFFVYIGGESPLKEKYIDAASELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLTMDGFLLYELGDTGKLVAIAVVDEKNTSIEHTRDFQFGHMDGNEYINTLLMDELKVPTVVVLNTSNQQYFLLDRQIKNAEDMVQFINNILDGTVNAQGGDSIVQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSETESPEPVEESKEQQEPRSGDPLVPAVQEPKDVLEKKKD", "length": 436, "header": "tr|A0A8D0WDN6-1|A0A4X1TWN6_PIG Computationally mapped isoform of Protein disulfide-isomerase TMX3 OS=Sus scrofa OX=9823 GN=TMX3 PE=1 SV=1 CANONICAL=A0A4X1TWN6-1" }, "locus": { "chromosome": "1", "start_pos": 154027911, "end_pos": 153988237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086383.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086383.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060305.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060305.1" } ] } }, { "isoform_ac": "A0A8W4FJ21-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6/entry#A0A8W4FJ21-1", "sequence": { "sequence": "MAARSRGAALGLCATVFLLDVAFCKGFVEDLDESIVYSFSYQGIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHVQKRHRVFFVYIGGESPLKEKYIDAASELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLTMDGFLLYELGDTGKLVAIAVVDEKNTSIEHTRLKSVIQEVARDYRDQFHRDFQFGHMDGNEYINTLLMDELKVPTVVVLNTSNQQYFLLDRQIKNAEDMVQFINNILDGTVNAQGGDSIVQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSETESPEPVEESKEQQEPRSGDPLVPAVQEPKDVLEKKKD", "length": 408, "header": "tr|A0A8W4FJ21-1|A0A4X1TWN6_PIG Computationally mapped isoform of Protein disulfide-isomerase TMX3 OS=Sus scrofa OX=9823 GN=TMX3 PE=1 SV=1 CANONICAL=A0A4X1TWN6-1" }, "locus": { "chromosome": "1", "start_pos": 154027911, "end_pos": 153988237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105163.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105163.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079229.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079229.1" } ] } }, { "isoform_ac": "F1SMY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6/entry#F1SMY1-1", "sequence": { "sequence": "MAARSRGAALGLCATVFLLDVAFCKGFVEDLDESFKDNRKDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHVQKRHRVFFVYIGGESPLKEKYIDAASELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLTMDGFLLYELGDTGKLVAIAVVDEKNTSIEHTRLKSVIQEVARDYRDQFHRDFQFGHMDGNEYINTLLMDELKVPTVVVLNTSNQQYFLLDRQIKNAEDMVQFINNILDGTVNAQGGDSIVQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSETESPEPVEESKEQQEPRSGDPLVPAVQEPKDVLEKKKD", "length": 441, "header": "tr|F1SMY1-1|A0A4X1TWN6_PIG Computationally mapped isoform of Protein disulfide-isomerase TMX3 OS=Sus scrofa OX=9823 GN=TMX3 PE=1 SV=3 CANONICAL=A0A4X1TWN6-1" }, "locus": { "chromosome": "1", "start_pos": 154027911, "end_pos": 153988237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005390.4", "url": "https://www.ensembl.org/id/ENSSSCT00000005390.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005255.3", "url": "https://www.ensembl.org/id/ENSSSCP00000005255.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SMY1", "url": "https://www.uniprot.org/uniprotkb/F1SMY1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518050", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518050", "resource": "KEGG Pathway" }, { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R402-1", "protein_name": "Protein disulfide-isomerase TMX3", "gene_name": "Tmx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLRALITGFTPRSMANAAGRRSWAALRLCAAVILLDLAVCKGFVEDLNESFKDNRKDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFDHVRKRHRVFFVYIGGESPLKEKYIDAASELIVYTYFFSASEDVVPEYVTLKEMPAVLVFKDDTYFVYDEYEDGDLSSWISRERFQNYLTMDGFLLYELGDTGKLVAIAVIDEKNTSLEHTRLKSIIQEVARDFRDHFHRDFQFGHMDGNDYINTLLMDELTVPTIVVLNTSNQQYFLLDRHIKDASDMVQFINSILDGTVPAQGGDSIFQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSEMENQEQIEESKEQESSSGGSLVPTVQESKDVLEKKKD", "length": 470 }, "evidence": [ { "id": "A0A4X1TWN6", "url": "https://omabrowser.org/oma/group/A0A4X1TWN6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BXZ1-1", "protein_name": "Protein disulfide-isomerase TMX3", "gene_name": "Tmx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANAVGRRSWAALRLCAAVILLDLAVCKGFVEDLNESFKDNRKDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFDHVRKRHRVFFVYIGGESPLKEKYIDAASELIVYTYFFSASEDVVPEYVTLKEMPAVLVFKDDTYFVYDEYEDGDLSSWISRERFQNYLTMDGFLLYELGDTGKLVAIAVIDEKNTSLEHTRLKSIIQEVARDFRDHFHRDFQFGHMDGNDYINTLLMDELTVPTIVVLNTSNQQYFLLDRHIKDASDMVQFINSILDGTVPAQGGDSIFQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSEMENQEQIEESKEQESSSGGSLAPTVQEPKDVLEKKKD", "length": 456 }, "evidence": [ { "id": "A0A4X1TWN6", "url": "https://omabrowser.org/oma/group/A0A4X1TWN6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94F09-1", "protein_name": "Protein disulfide-isomerase 5-2", "gene_name": "PDIL5-2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRSLKLLLCWISFLTLSISISASSDDQFTLDGTVLELTDSNFDSAISTFDCIFVDFYAPWCGHCKRLNPELDAAAPILAKLKQPIVIAKLNADKYSRLARKIEIDAFPTLMLYNHGVPMEYYGPRKADLLVRYLKKFVAPDVAVLESDSTVKEFVEDAGTFFPVFIGFGLNESIISGLGRKYKKKAWFAVSKEVSEDTMVSYDFDKAPALVANHPTYNEHSVFYGPFEDGFLEEFVKQSFLPLILPINHDTLKLLKDDERKIVLTIVEDETHESLEKLYKALRAAAHANRDLVFGYVGVKQFEEFVDSFHVDKKTNLPKIVVWDGDEEYDQVTGIETITQEEDHLTQVSRFLEGYREGRTEKKKINGPSFMGFINSMIGIRSVYILVFLVAVIMMLRSLGQVEEPTGVRTATAVRERVDQATTVPEDESSEHKPSDKKED", "length": 440 }, "evidence": [ { "id": "A0A4X1TWN6", "url": "https://omabrowser.org/oma/group/A0A4X1TWN6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96JJ7-1", "protein_name": "Protein disulfide-isomerase TMX3", "gene_name": "TMX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLLMDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDSILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSENENQEQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD", "length": 454 }, "evidence": [ { "id": "A0A4X1TWN6", "url": "https://omabrowser.org/oma/group/A0A4X1TWN6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6" } ], "pmid": "" }, { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWN6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-481044", "name": "Surface deployment of platelet alpha granule membrane components", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-481044", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-481044" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TWN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWN6" }, { "id": "PS51352", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 131, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 258, "end_pos": 260 }, { "start_pos": 313, "end_pos": 315 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TRT7-1", "uniprot_ac": "A0A4X1TRT7", "uniprot_id": "A0A4X1TRT7_PIG", "mass": { "chemical_mass": 28193.0, "monoisotopic_mass": 28193.0 }, "refseq": { "ac": "XP_003130430", "name": "phosducin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130430" }, "gene_names": [ { "name": "PDC", "type": "recommended", "evidence": [ { "id": "A0A4X1TRT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7" } ] }, { "name": "PDC", "type": "synonym", "evidence": [ { "id": "XP_003130430", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130430" } ] } ], "protein_names": [ { "name": "Phosducin", "type": "recommended", "evidence": [ { "id": "A0A4X1TRT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7/entry#names_and_taxonomy" } ] }, { "name": "phosducin", "type": "synonym", "evidence": [ { "id": "XP_003130430", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130430" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PDC", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7", "locus": { "chromosome": "9", "start_pos": 127601385, "end_pos": 127619697, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015578", "url": "https://www.ensembl.org/id/ENSSSCG00000015578" } ] } } ], "crossref": [ { "id": "A0A4X1TRT7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TRT7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02987", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02987", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100518570", "url": "https://www.ncbi.nlm.nih.gov/gene/100518570", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023196", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023196", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518570", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518570", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PKYGYLC", "url": "https://omabrowser.org/oma/group/PKYGYLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TRT7", "url": "https://www.orthodb.org/?gene=A0A4X1TRT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46052", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46052", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46052:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46052:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003130430", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130430", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TRT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TRT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEAQSQSLEEDFEGQATHTGPKGVINDWRKFKLESEDSDSFPPSKKDILRKMSSPQSRDDKDSKERLSRKMSVQEYELIHQDKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELESGEQFLETIEKEQKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPMVKFCKIKASNTGAGDRFSSDVLPTLLVYKGGELISNFISVAEQFAEEFFTGDVESFLNEYGLLPEKEIHVIEQTTMEEDME", "length": 245, "header": "tr|A0A4X1TRT7-1|A0A4X1TRT7_PIG Isoform 1 of Phosducin OS=Sus scrofa OX=9823 GN=PDC PE=1 SV=1 CANONICAL=A0A4X1TRT7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TRT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7/entry#A0A4X1TRT7-1", "sequence": { "sequence": "MEEAQSQSLEEDFEGQATHTGPKGVINDWRKFKLESEDSDSFPPSKKDILRKMSSPQSRDDKDSKERLSRKMSVQEYELIHQDKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELESGEQFLETIEKEQKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPMVKFCKIKASNTGAGDRFSSDVLPTLLVYKGGELISNFISVAEQFAEEFFTGDVESFLNEYGLLPEKEIHVIEQTTMEEDME", "length": 245, "header": "tr|A0A4X1TRT7-1|A0A4X1TRT7_PIG Isoform 1 of Phosducin OS=Sus scrofa OX=9823 GN=PDC PE=1 SV=1 CANONICAL=A0A4X1TRT7-1" }, "locus": { "chromosome": "9", "start_pos": 127608361, "end_pos": 127601443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016971.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016971.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016517.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016517.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518570", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518570", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PA22-1", "protein_name": "Phosducin", "gene_name": "PDC", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEENANTSLEEDFEGQATHTGPKGVINDWRKFKLESEDKDSLPLSKKEILRQMSSPHRSFSKDDKDTRERFCRKMSMQEYELINDEKEDESCLQKYRKRCMQDMHQRLSFGPKYGYLCELQNGEQFLEAIEKERKTTTVIVHIYEDGIKGCNALNSSLTCLAAEYTTVKFCKIKASNTGAGDRFSDEVLPTLLVYKGGELLSNFISVSEQFNEEFFAVDVESFLNEYGLLPERELPALGNVNTDEQDVE", "length": 249 }, "evidence": [ { "id": "A0A4X1TRT7", "url": "https://omabrowser.org/oma/group/A0A4X1TRT7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8C2MI12-1", "protein_name": "Phosducin", "gene_name": "Pdc", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEEARSQSIEEDFEGQATHTGPKGVINDWRKFKLESEDGDSIPPSKKEILRQMSSPQSKDDSKDRVSRKMSIQEYELIHQDKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGEQFLETIEKEQKVTTIVVNIYEDGVKGCDALNSSLACLAVEYPMVKFCKIKASNTGAGDRFSSDVLPTLLVYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEKEIHDLEQTNMEEDEDIE", "length": 245 }, "evidence": [ { "id": "A0A4X1TRT7", "url": "https://omabrowser.org/oma/group/A0A4X1TRT7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MSE1-1", "protein_name": "Phosducin", "gene_name": "PDC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKAKSKSLEEDFEGQASHTGPKGVINDWRKFKLESEDSDSVAPSKKEILRQMSSPQSRDDKDSKERFSRKMSVQEYELIHKDKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELESGEQFLETIEKEQKITTIVVHIYEDGIKGCDALNSSLICLAAEYPMVKFCKIKASNTGAGDRFSSDVLPTLLVYKGGELLSNFISVTEQLAEEFFTGDVESFLNEYGLLPEKEMHVLEQSNMEEDME", "length": 245 }, "evidence": [ { "id": "A0A4X1TRT7", "url": "https://omabrowser.org/oma/group/A0A4X1TRT7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F8W512-1", "protein_name": "Phosducin", "gene_name": "pdca", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSESPEIEELPATQTGPKGVIHDWRKFKLESEDHESIPSNKRELLRQMSNPKSSDDPREKVNRKMSVQEYEMIQEEDEQCLRKYRKQCMQDMHERLSFGPKFDSVFDLESGEAFLDVIENEHRLTLVVVHIYEDGIRGCDALNNCLTCLAAEYSTVKFCRIRASATGAGERFSEDVLPTLLVYKAGEMLGNFLCVTKHMNEEFFATDVENFLNEYGLLPEKEFAASPDEEENADVE", "length": 236 }, "evidence": [ { "id": "A0A4X1TRT7", "url": "https://omabrowser.org/oma/group/A0A4X1TRT7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P20941-1", "protein_name": "Phosducin", "gene_name": "PDC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEAKSQSLEEDFEGQATHTGPKGVINDWRKFKLESQDSDSIPPSKKEILRQMSSPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE", "length": 246 }, "evidence": [ { "id": "A0A4X1TRT7", "url": "https://omabrowser.org/oma/group/A0A4X1TRT7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P20942-1", "protein_name": "Phosducin", "gene_name": "Pdc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEAASQSLEEDFEGQATHTGPKGVINDWRKFKLESEDGDSIPPSKKEILRQMSSPQSRDDKDSKERMSRKMSIQEYELIHQDKEDEGCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGEQFLETIEKEQKVTTIVVNIYEDGVRGCDALNSSLECLAAEYPMVKFCKIRASNTGAGDRFSSDVLPTLLVYKGGELISNFISVAEQFAEDFFAADVESFLNEYGLLPEREIHDLGQTNTEDEDIE", "length": 246 }, "evidence": [ { "id": "A0A4X1TRT7", "url": "https://omabrowser.org/oma/group/A0A4X1TRT7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9QW08-1", "protein_name": "Phosducin", "gene_name": "Pdc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEAASQSLEEDFEGQATHTGPKGVINDWRKFKLESEDGDSIPPSKKEILRQMSSPQSRDDSKERMSRKMSIQEYELIHQDKEDESCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGEQFLETIEKEQKVTTIVVNIYEDGVRGCDALNSSLACLAVEYPMVKFCKIKASNTGAGDRFSTDVLPTLLVYKGGELISNFISVAEQFAEEFFAVDVESFLNEYGLLPEREIHDLEQTNMEDEDIE", "length": 244 }, "evidence": [ { "id": "A0A4X1TRT7", "url": "https://omabrowser.org/oma/group/A0A4X1TRT7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TRT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TRT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TRT7" }, { "id": "PF02114", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02114" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosducin", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 243, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TS62-1", "uniprot_ac": "A0A4X1TS62", "uniprot_id": "A0A4X1TS62_PIG", "mass": { "chemical_mass": 49416.0, "monoisotopic_mass": 49416.0 }, "refseq": { "ac": "XP_003132941", "name": "RING finger and transmembrane domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132941" }, "gene_names": [ { "name": "RNFT2", "type": "recommended", "evidence": [ { "id": "A0A4X1TS62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62" } ] }, { "name": "RNFT2", "type": "synonym", "evidence": [ { "id": "XP_003132941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132941" } ] } ], "protein_names": [ { "name": "RING finger and transmembrane domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_003132941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132941" } ] }, { "name": "Ring finger protein, transmembrane 2", "type": "synonym", "evidence": [ { "id": "A0A4X1TS62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TS62", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RNFT2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62", "locus": { "chromosome": "14", "start_pos": 35635720, "end_pos": 35705759, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009862", "url": "https://www.ensembl.org/id/ENSSSCG00000009862" } ] } } ], "crossref": [ { "id": "A0A4X1TS62", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TS62", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16742", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16742", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519873", "url": "https://www.ncbi.nlm.nih.gov/gene/100519873", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519873", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519873", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HHRQPPH", "url": "https://omabrowser.org/oma/group/HHRQPPH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TS62", "url": "https://www.orthodb.org/?gene=A0A4X1TS62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15860:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15860:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003132941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132941", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TS62", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TS62-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWFLTVNQVLRKMQRRHSSNTDNVPPERNRSQALSSEASVDEGGVFESLKAEAASPPALFSGLSGLPAGSLPTTPFPSSLVLGASAGKGDVFLQMPASREEGGGRGEGGTYHHRQPHHHFHHSGHRGGSLLQHVGGDHRAHSDDGGDEQPGTPAPALSELKAVICWLQKGLPFILILLAKVCFQHKLGIAVCIGMASTFAYANSTLREQVSLKEKRSVLVILWILAFLAGNTLYVLYTFSSQQLYNSLIFLKPNLETLDFFDLLWIVGIADFVLKYITIALKCLVVALPKIILAVKSKGKFYLVIEELSQLFRSLVPIQLWYKYIMGDDTSNSYFLGGVLIILYSLCKSFDICGRLGGVRKALKLLCTSQNYGVRATGQQCTEAGDICAICQAEFREPLILMCQHVFCEECLCLWLDRERTCPLCRSVAVDTLRCWKDGATSAHFQVY", "length": 448, "header": "tr|A0A4X1TS62-1|A0A4X1TS62_PIG Isoform 1 of Ring finger protein, transmembrane 2 OS=Sus scrofa OX=9823 GN=RNFT2 PE=4 SV=1 CANONICAL=A0A4X1TS62-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TS62-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62/entry#A0A4X1TS62-1", "sequence": { "sequence": "MWFLTVNQVLRKMQRRHSSNTDNVPPERNRSQALSSEASVDEGGVFESLKAEAASPPALFSGLSGLPAGSLPTTPFPSSLVLGASAGKGDVFLQMPASREEGGGRGEGGTYHHRQPHHHFHHSGHRGGSLLQHVGGDHRAHSDDGGDEQPGTPAPALSELKAVICWLQKGLPFILILLAKVCFQHKLGIAVCIGMASTFAYANSTLREQVSLKEKRSVLVILWILAFLAGNTLYVLYTFSSQQLYNSLIFLKPNLETLDFFDLLWIVGIADFVLKYITIALKCLVVALPKIILAVKSKGKFYLVIEELSQLFRSLVPIQLWYKYIMGDDTSNSYFLGGVLIILYSLCKSFDICGRLGGVRKALKLLCTSQNYGVRATGQQCTEAGDICAICQAEFREPLILMCQHVFCEECLCLWLDRERTCPLCRSVAVDTLRCWKDGATSAHFQVY", "length": 448, "header": "tr|A0A4X1TS62-1|A0A4X1TS62_PIG Isoform 1 of Ring finger protein, transmembrane 2 OS=Sus scrofa OX=9823 GN=RNFT2 PE=4 SV=1 CANONICAL=A0A4X1TS62-1" }, "locus": { "chromosome": "14", "start_pos": 35703567, "end_pos": 35637369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010810.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010810.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010527.2", "url": "https://www.ensembl.org/id/ENSSSCP00000010527.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TS62", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519873", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519873", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GTP0-1", "protein_name": "RING finger and transmembrane domain-containing protein 2 isoform X1", "gene_name": "Rnft2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MWLLAVHQVLRKMQRRHSSNTDNIPPERSRSQALSPEASVDEGGVFESLKAETTSPPALFSGLAGGLPANPFPAGLVLGSTAGGGDVFIPMPATRDEAGGRSTEGSSYHHRQSHHHFHHAAHRGGSLLQHVGGDHRGHSEEGVDEQPGTPAPALSELKAVICWLQKGLPFILILLAKLCFQHKLGIAVCIGMASTFAYANSTLREQVSLKEKRSVLVILWILAFLAGNTLYVLYTFSSQQLYSSLIFLKPNLETLDFFDLLWIVGIADFVLKYITIALKCLIVALPKIILAVKSKGKFYLVIEELSQLFRSLVPIQLWYKYIMGDDSSNSYFLGGVLIILYSLCKSFDICGRVGGVRKALKLLCTSQNYGVRATGQQCTEAGAICAICQAEFRDPMILLCQCSQVWWCTSLIPALERWRQKNLPLQVQGQPGLHLDFKTEDDNKWLCFYEI", "length": 451 }, "evidence": [ { "id": "A0A4X1TS62", "url": "https://omabrowser.org/oma/group/A0A4X1TS62/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LKB5-1", "protein_name": "Ring finger protein, transmembrane 2", "gene_name": "Rnft2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLLAAHQVLRKMQRRHSSNTDNIPPERSRSQALSPEASVDEGGVFESLKAEPASPPTLFSGLAGGLPASPFPAGLVLGSTAGGGDVFIPMPATRDEAGGRSTEGSTYHHRQAHHHFHHGAHRGGSLLQHVGGDHRGHSEEGVDEQPGTPAPALSELKAVICWLQKGLPFILILLAKLCFQHKLGIAVCIGMASTFAYANSALREQVSLKEKRSVLVILWILAFLAGNTLYVLYTFSSQQLYSSLIFLKPNLETLDFFDLLWIVGIADFVLKYITIALKCLIVALPKIILAVKSKGKFYLVIEELSQLFRSLVPIQLWYKYIMGDDSSDSYFLGGVLIILYSLCKSFDICGRVGGLRKALKLLCTSQNYGVRATGQQCTEAGAVCAICQAEFRDPMILLCQHVFCEECLCLWLDRERTCPLCRSVAVDTLRCWKDGATSAHLQLLVLNAENWCELRGYSLTQVCTQEPLGECPTCEHQASPT", "length": 482 }, "evidence": [ { "id": "A0A4X1TS62", "url": "https://omabrowser.org/oma/group/A0A4X1TS62/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UF64-1", "protein_name": "RING finger and transmembrane domain-containing protein 2", "gene_name": "Rnft2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLLAAHQVLRKMQRRHSSNTDNIPPERSRSQALSPEASVDEGGVFESLKAETASPPALFSGLAGGLPASPFPAGLVLGSTAGGGDVFIPMPATRDEAGGRSAEGSTYHHRQAHHHFHHGAHRGGSLLQHVGGDHRGHSEEGVDEQPGTPAPALSELKAVISWLQKGLPFILILLAKLCFQHKLGIAVCIGMASTFAYANSTLREQVSLKEKRSVLVILWILAFLAGNTMYVLYTFSSQQLYSSLIFLKPNLETLDFFDLLWIVGIADFVLKYITIALKCLIVALPKIILAVKSKGKFYLVIEELSQLFRSLVPIQLWYKYIMGDDSSNSYFLGGVLIVLYSLCKSFDICGRVGGLRKALKLLCTSQNYGVRATGQQCTEAGAVCAICQAEFRDPMILLCQHVFCEECLCLWLDRERTCPLCRSVAVDTLRCWKDGATSAHLQVY", "length": 445 }, "evidence": [ { "id": "A0A4X1TS62", "url": "https://omabrowser.org/oma/group/A0A4X1TS62/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96EX2-1", "protein_name": "E3 ubiquitin-protein ligase RNFT2", "gene_name": "RNFT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLFTVNQVLRKMQRRHSSNTDNIPPERNRSQALSSEASVDEGGVFESLKAEAASPPALFSGLSGSLPTSSFPSSLVLGSSAGGGDVFIQMPASREEGGGRGEGGAYHHRQPHHHFHHGGHRGGSLLQHVGGDHRGHSEEGGDEQPGTPAPALSELKAVICWLQKGLPFILILLAKLCFQHKLGIAVCIGMASTFAYANSTLREQVSLKEKRSVLVILWILAFLAGNTLYVLYTFSSQQLYNSLIFLKPNLEMLDFFDLLWIVGIADFVLKYITIALKCLIVALPKIILAVKSKGKFYLVIEELSQLFRSLVPIQLWYKYIMGDDSSNSYFLGGVLIVLYSLCKSFDICGRVGGVRKALKLLCTSQNYGVRATGQQCTEAGDICAICQAEFREPLILLCQHVFCEECLCLWLDRERTCPLCRSVAVDTLRCWKDGATSAHFQVY", "length": 444 }, "evidence": [ { "id": "A0A4X1TS62", "url": "https://omabrowser.org/oma/group/A0A4X1TS62/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TS62", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TS62", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TS62", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of ERAD pathway", "id": "GO:1904294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904294", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TS62", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TS62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TS62" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 388, "end_pos": 426, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TSN1-1", "uniprot_ac": "A0A4X1TSN1", "uniprot_id": "A0A4X1TSN1_PIG", "mass": { "chemical_mass": 39925.0, "monoisotopic_mass": 39925.0 }, "refseq": { "ac": "XP_020954676", "name": "insulin gene enhancer protein ISL-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954676" }, "gene_names": [ { "name": "ISL2", "type": "recommended", "evidence": [ { "id": "A0A4X1TSN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1" } ] }, { "name": "ISL2", "type": "synonym", "evidence": [ { "id": "XP_020954676", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954676" } ] } ], "protein_names": [ { "name": "Insulin gene enhancer protein ISL-2", "type": "recommended", "evidence": [ { "id": "A0A4X1TSN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1/entry#names_and_taxonomy" } ] }, { "name": "insulin gene enhancer protein ISL-2", "type": "synonym", "evidence": [ { "id": "XP_020954676", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954676" } ] } ], "function": [ { "annotation": "Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSN1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1#function" }, { "database": "UniProtKB", "id": "ARBA00055727", "url": "https://www.uniprot.org/uniprotkb/ARBA00055727#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSN1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ISL2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1", "locus": { "chromosome": "7", "start_pos": 56577253, "end_pos": 56571419, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000033348", "url": "https://www.ensembl.org/id/ENSSSCG00000033348" } ] } } ], "crossref": [ { "id": "A0A4X1TSN1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TSN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09366", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09366", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09471", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09471", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110261563", "url": "https://www.ncbi.nlm.nih.gov/gene/110261563", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110261563", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261563", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMHPNEV", "url": "https://omabrowser.org/oma/group/AMHPNEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TSN1", "url": "https://www.orthodb.org/?gene=A0A4X1TSN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24204", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24204", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24204:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24204:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020954676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954676", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TSN1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TSN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDIIFHYPFLGTMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAADSPRSPGPLPGPRGLHLPDPGSGRQPSLRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHNDKTSLQGLTGTPLVAGSPIRHESAVQGSAVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET", "length": 359, "header": "tr|A0A4X1TSN1-1|A0A4X1TSN1_PIG Isoform 1 of Insulin gene enhancer protein ISL-2 OS=Sus scrofa OX=9823 GN=ISL2 PE=4 SV=1 CANONICAL=A0A4X1TSN1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TSN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1/entry#A0A4X1TSN1-1", "sequence": { "sequence": "MVDIIFHYPFLGTMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAADSPRSPGPLPGPRGLHLPDPGSGRQPSLRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHNDKTSLQGLTGTPLVAGSPIRHESAVQGSAVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET", "length": 359, "header": "tr|A0A4X1TSN1-1|A0A4X1TSN1_PIG Isoform 1 of Insulin gene enhancer protein ISL-2 OS=Sus scrofa OX=9823 GN=ISL2 PE=4 SV=1 CANONICAL=A0A4X1TSN1-1" }, "locus": { "chromosome": "7", "start_pos": 56576569, "end_pos": 56571528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049281.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049281.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054636.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054636.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSN1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110261563", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261563", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P50480-1", "protein_name": "Insulin gene enhancer protein ISL-2", "gene_name": "Isl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAQCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGTPPGLHLPDAGSGQQVSLRTHVHKQAEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKASLQGLTGTLLVAGSPSAHENAVQGSAVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET", "length": 360 }, "evidence": [ { "id": "A0A4X1TSN1", "url": "https://omabrowser.org/oma/group/A0A4X1TSN1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P53406-1", "protein_name": "Insulin gene enhancer protein isl-2a", "gene_name": "isl2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDILPHPSFLGDMGDHSKKKSGIAMCVGCGSQIHDQYILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCNIGFCSSDLVMRARDNVYHMECFRCSVCSRHLLPGDEFSLRDEELLCRADHGLLMERASAGSPISPGNIHSSRPLHIPEPVPVRQPPHRNHVHKQSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHNDKTNLQGLTGTPLVAGSPIRHDTTVQGNPVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET", "length": 359 }, "evidence": [ { "id": "A0A4X1TSN1", "url": "https://omabrowser.org/oma/group/A0A4X1TSN1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96A47-1", "protein_name": "Insulin gene enhancer protein ISL-2", "gene_name": "ISL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET", "length": 359 }, "evidence": [ { "id": "A0A4X1TSN1", "url": "https://omabrowser.org/oma/group/A0A4X1TSN1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CXV0-1", "protein_name": "Insulin gene enhancer protein ISL-2", "gene_name": "Isl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAQCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPSLRTHVHKQAEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKASLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET", "length": 359 }, "evidence": [ { "id": "A0A4X1TSN1", "url": "https://omabrowser.org/oma/group/A0A4X1TSN1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSN1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSN1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSN1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1" } ], "pmid": "" }, { "name": "neuron fate specification", "id": "GO:0048665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048665", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSN1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSN1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSN1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1" } ], "pmid": "" }, { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TSN1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TSN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 189, "end_pos": 249, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TSN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TSN1" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 87, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 332, "end_pos": 334 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TT46-1", "uniprot_ac": "A0A4X1TT46", "uniprot_id": "A0A4X1TT46_PIG", "mass": { "chemical_mass": 27876.0, "monoisotopic_mass": 27876.0 }, "refseq": {}, "gene_names": [ { "name": "IZUMO1R", "type": "recommended", "evidence": [ { "id": "A0A4X1TT46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46" } ] } ], "protein_names": [ { "name": "IZUMO1 receptor, JUNO", "type": "synonym", "evidence": [ { "id": "A0A4X1TT46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IZUMO1R", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46", "locus": { "chromosome": "9", "start_pos": 26520860, "end_pos": 26517292, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014952", "url": "https://www.ensembl.org/id/ENSSSCG00000014952" } ] } } ], "crossref": [ { "id": "A0A4X1TT46", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TT46", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10517", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10517", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10517:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10517:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TT46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TT46-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGWWRQLLLGLWAVLPTWAGPELLNICMNAKPHKPEPSPEDKLYEECIPWKHNACCTADTSWEAHLDVALLYNFSLVHCGLMMPGCQKHFLQAICFYECSPNLGPWIQQTDPHGQAERILDAPLCQEDCEEWWADCRTSYTCKSNWLGGWTWSRGKHRCPARALCHPFPHYFPTPADLCEKIWSHSFKASPERRDSGRCLQKWFEPTRINPNAAVARLFASPAPSWALSYRLMAFALSLSLLS", "length": 243, "header": "tr|A0A4X1TT46-1|A0A4X1TT46_PIG Isoform 1 of IZUMO1 receptor, JUNO OS=Sus scrofa OX=9823 GN=IZUMO1R PE=3 SV=1 CANONICAL=A0A4X1TT46-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TT46-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46/entry#A0A4X1TT46-1", "sequence": { "sequence": "MGWWRQLLLGLWAVLPTWAGPELLNICMNAKPHKPEPSPEDKLYEECIPWKHNACCTADTSWEAHLDVALLYNFSLVHCGLMMPGCQKHFLQAICFYECSPNLGPWIQQTDPHGQAERILDAPLCQEDCEEWWADCRTSYTCKSNWLGGWTWSRGKHRCPARALCHPFPHYFPTPADLCEKIWSHSFKASPERRDSGRCLQKWFEPTRINPNAAVARLFASPAPSWALSYRLMAFALSLSLLS", "length": 243, "header": "tr|A0A4X1TT46-1|A0A4X1TT46_PIG Isoform 1 of IZUMO1 receptor, JUNO OS=Sus scrofa OX=9823 GN=IZUMO1R PE=3 SV=1 CANONICAL=A0A4X1TT46-1" }, "locus": { "chromosome": "9", "start_pos": 26520857, "end_pos": 26517292, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016311.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016311.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015874.4", "url": "https://www.ensembl.org/id/ENSSSCP00000015874.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 174, "start_aa": "Thr", "end_pos": 174, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr174", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sperm-egg recognition", "id": "GO:0035036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035036", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46" } ], "pmid": "" }, { "name": "fusion of sperm to egg plasma membrane involved in single fertilization", "id": "GO:0007342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007342", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT46", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TT46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT46" }, { "id": "PF03024", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03024" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Folate receptor-like", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 201, "start_aa": "Ile", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 174 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TT87-1", "uniprot_ac": "A0A4X1TT87", "uniprot_id": "A0A4X1TT87_PIG", "mass": { "chemical_mass": 43577.0, "monoisotopic_mass": 43577.0 }, "refseq": { "ac": "XP_001924578", "name": "endonuclease 8-like 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924578" }, "gene_names": [ { "name": "NEIL1", "type": "recommended", "evidence": [ { "id": "A0A4X1TT87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ] }, { "name": "NEIL1", "type": "synonym", "evidence": [ { "id": "XP_001924578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924578" } ] } ], "protein_names": [ { "name": "Endonuclease 8-like 1", "type": "recommended", "evidence": [ { "id": "A0A4X1TT87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87/entry#names_and_taxonomy" } ] }, { "name": "4.2.99.18", "type": "synonym", "evidence": [ { "id": "A0A4X1TT87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87/entry#names_and_taxonomy" } ] }, { "name": "DNA glycosylase/AP lyase Neil1", "type": "synonym", "evidence": [ { "id": "A0A4X1TT87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87/entry#names_and_taxonomy" } ] }, { "name": "DNA-(apurinic or apyrimidinic site) lyase Neil1", "type": "synonym", "evidence": [ { "id": "A0A4X1TT87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87/entry#names_and_taxonomy" } ] }, { "name": "Endonuclease VIII-like 1", "type": "synonym", "evidence": [ { "id": "A0A4X1TT87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87/entry#names_and_taxonomy" } ] }, { "name": "Nei homolog 1", "type": "synonym", "evidence": [ { "id": "A0A4X1TT87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87/entry#names_and_taxonomy" } ] }, { "name": "Nei-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A4X1TT87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87/entry#names_and_taxonomy" } ] }, { "name": "endonuclease 8-like 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001924578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924578" } ] } ], "function": [ { "annotation": "Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as a DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Has DNA glycosylase/lyase activity towards mismatched uracil and thymine, in particular in U:C and T:C mismatches. Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87#function" }, { "database": "UniProtKB", "id": "ARBA00055258", "url": "https://www.uniprot.org/uniprotkb/ARBA00055258#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NEIL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87", "locus": { "chromosome": "7", "start_pos": 58261769, "end_pos": 58268522, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001882", "url": "https://www.ensembl.org/id/ENSSSCG00000001882" } ] } } ], "crossref": [ { "id": "A0A4X1TT87", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TT87", "database": "AlphaFoldDB", "categories": [] }, { "id": "100155341", "url": "https://www.ncbi.nlm.nih.gov/gene/100155341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155341", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155341", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IMFEYKS", "url": "https://omabrowser.org/oma/group/IMFEYKS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TT87", "url": "https://www.orthodb.org/?gene=A0A4X1TT87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22993", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22993", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22993:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22993:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-110328", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110328", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-110329", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110329", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5649702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5649702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001924578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924578", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TT87-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEGPELHLASHFVNEACGELVFGGCVEKSPVSRNPEVPFESSAYHISALARGKELRLTLSPLPGAQPPQEPLALVFRFGMTGSFQLVPRDALPPHAHLRFYTAPPSPQLALCFVDIRRFGRWELGGEWDPGRGPCVLLEYEQFRENVLRNLADKAFDRPICEALLDQRFFNGIGNYLRAEILHRLRIPPFEKARTVLEALQRHRLSPELTLSQKIKAKLQNPDLLELCHSVPKEVVQLGGKGYGPESREEDFAAFRAWLRCYGTPGMNSLRDRHGRTIWFQGDPGPLAPKGGKSRKKKSKGAQQGPEDRVEDPTLQNKATLRTRRTQRGLEQSTAQQPKGTSLQQDPETPLVPEKGKRRRRQATSGRRRPQKITGDTPSLEPEGTSAS", "length": 389, "header": "tr|A0A4X1TT87-1|A0A4X1TT87_PIG Isoform 1 of Endonuclease 8-like 1 OS=Sus scrofa OX=9823 GN=NEIL1 PE=3 SV=1 CANONICAL=A0A4X1TT87-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TT87-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87/entry#A0A4X1TT87-1", "sequence": { "sequence": "MPEGPELHLASHFVNEACGELVFGGCVEKSPVSRNPEVPFESSAYHISALARGKELRLTLSPLPGAQPPQEPLALVFRFGMTGSFQLVPRDALPPHAHLRFYTAPPSPQLALCFVDIRRFGRWELGGEWDPGRGPCVLLEYEQFRENVLRNLADKAFDRPICEALLDQRFFNGIGNYLRAEILHRLRIPPFEKARTVLEALQRHRLSPELTLSQKIKAKLQNPDLLELCHSVPKEVVQLGGKGYGPESREEDFAAFRAWLRCYGTPGMNSLRDRHGRTIWFQGDPGPLAPKGGKSRKKKSKGAQQGPEDRVEDPTLQNKATLRTRRTQRGLEQSTAQQPKGTSLQQDPETPLVPEKGKRRRRQATSGRRRPQKITGDTPSLEPEGTSAS", "length": 389, "header": "tr|A0A4X1TT87-1|A0A4X1TT87_PIG Isoform 1 of Endonuclease 8-like 1 OS=Sus scrofa OX=9823 GN=NEIL1 PE=3 SV=1 CANONICAL=A0A4X1TT87-1" }, "locus": { "chromosome": "7", "start_pos": 58266849, "end_pos": 58261975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042301.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042301.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040249.1", "url": "https://www.ensembl.org/id/ENSSSCP00000040249.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155341", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155341", "resource": "KEGG Pathway" }, { "id": "R-SSC-110328", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110328", "resource": "Reactome", "description": "Recognition and association of DNA glycosylase with site containing an affected pyrimidine" }, { "id": "R-SSC-110329", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110329", "resource": "Reactome", "description": "Cleavage of the damaged pyrimidine" }, { "id": "R-SSC-5649702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5649702", "resource": "Reactome", "description": "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F7ESG0-1", "protein_name": "Endonuclease 8-like 1", "gene_name": "Neil1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDARQTQGQIKLWLMNDESFASGVPTGPSHSSFRMPEGPELHLASHFVNEICKGLVFGGCVEKSSVSRNPEVPFESSAYHISALARGKELRLTLSPLPGSHPPQKPLSLVFRFGMSGSFQLVPAEALPRHAHLRFYTAPPAPRLALCFVDIRRFGHWDPGGEWQPGRGPCVLLEYERFRENVLRNLSDKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKARTVLEALQQCRLSPELTLSQKVKAKLQNPDLLELCHLVPKEVVQLGGKGYGPERGEEDFAAFRAWLRCYAVPGMSSLRDRHGRTIWFQGDPGPLAPKGGRSRKKKSQETQLEAEDRKEDPPSKSISRTQRARKHCPKNVPQQSEGASLPQNLETPAVPEKGKRRGRRASTGRHRGPKSKPDTQPREAGEISAS", "length": 421 }, "evidence": [ { "id": "A0A4X1TT87", "url": "https://omabrowser.org/oma/group/A0A4X1TT87/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K4Q6-1", "protein_name": "Endonuclease 8-like 1", "gene_name": "Neil1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPEGPELHLASHFVNETCKGLVFGGCVEKSSVSRNPEVPFESSAYHISALARGKELRLTLSPLPGSQPPQKPLSLVFRFGMSGSFQLVPAEALPRHAHLRFYTAPPAPRLALCFVDIRRFGHWDPGGEWQPGRGPCVLLEYERFRENVLRNLSDKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKARTVLEALQQCRPSPELTLSQKIKAKLQNPDLLELCHLVPKEVVQLGGKGYGPERGEEDFAAFRAWLRCYGVPGMSSLRDRHGRTIWFQGDPGPLAPKGGRSQKKKSQETQLGAEDRKEDLPLSSKSVSRMRRARKHPPKRIAQQSEGAGLQQNQETPTAPEKGKRRGQRASTGHRRRPKTIPDTRPREAGESSAS", "length": 389 }, "evidence": [ { "id": "A0A4X1TT87", "url": "https://omabrowser.org/oma/group/A0A4X1TT87/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96FI4-1", "protein_name": "Endonuclease 8-like 1", "gene_name": "NEIL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPEGPELHLASQFVNEACRALVFGGCVEKSSVSRNPEVPFESSAYRISASARGKELRLILSPLPGAQPQQEPLALVFRFGMSGSFQLVPREELPRHAHLRFYTAPPGPRLALCFVDIRRFGRWDLGGKWQPGRGPCVLQEYQQFRENVLRNLADKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKARSVLEALQQHRPSPELTLSQKIRTKLQNPDLLELCHSVPKEVVQLGGKGYGSESGEEDFAAFRAWLRCYGMPGMSSLQDRHGRTIWFQGDPGPLAPKGRKSRKKKSKATQLSPEDRVEDALPPSKAPSRTRRAKRDLPKRTATQRPEGTSLQQDPEAPTVPKKGRRKGRQAASGHCRPRKVKADIPSLEPEGTSAS", "length": 390 }, "evidence": [ { "id": "A0A4X1TT87", "url": "https://omabrowser.org/oma/group/A0A4X1TT87/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "pmid": "" }, { "name": "DNA N-glycosylase activity", "id": "GO:0019104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019104", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "pmid": "" }, { "name": "DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0003906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003906", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "pmid": "" }, { "name": "class I DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0140078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140078", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TT87", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-5649658", "name": "NEIL1 cleaves DHU from damaged DNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5649658", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5649658" } ] }, { "id": "R-SSC-5649664", "name": "NEIL1 cleaves FapyG from damaged DNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5649664", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5649664" } ] }, { "id": "R-SSC-5649673", "name": "NEIL1 cleaves FapyA from damaged DNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5649673", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5649673" } ] }, { "id": "R-SSC-5649705", "name": "PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5649705", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5649705" } ] }, { "id": "R-SSC-5649708", "name": "NEIL1,NEIL2 recruits POLB to incised AP site", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5649708", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5649708" } ] }, { "id": "R-SSC-5649711", "name": "NEIL1,NEIL2 incises DNA strand 5' to the AP site", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5649711", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5649711" } ] }, { "id": "R-SSC-5649723", "name": "POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5649723", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5649723" } ] }, { "id": "R-SSC-5649725", "name": "POLB excises the NEIL1,NEIL2-bound AP site (5'dRP)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5649725", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5649725" } ] }, { "id": "R-SSC-5649726", "name": "LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5649726", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5649726" } ] }, { "id": "R-SSC-5649734", "name": "LIG3 ligates NEIL1,NEIL2-generated single strand break", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5649734", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5649734" } ] }, { "id": "R-SSC-9629149", "name": "NEIL1 cleaves thymine glycol from damaged DNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9629149", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9629149" } ] }, { "id": "R-SSC-9629918", "name": "NEIL1 translocates to the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nucleoplasm", "input_participant_list": [ "R-SSC-9629909" ], "output_participant_list": [ "R-SSC-5649648" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9629918", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9629918" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-5649648", "participant_name": "NEIL1 [nucleoplasm]", "crossref": [ { "id": "XP_013833516.1", "database": "RefSeq", "url": "" }, { "id": "A0A4X1TT87", "database": "UniProt", "url": "" }, { "id": "XP_020954687.1", "database": "RefSeq", "url": "" }, { "id": "XP_020954688.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000040249", "database": "ENSEMBL", "url": "" }, { "id": "XP_020954690.1", "database": "RefSeq", "url": "" }, { "id": "XP_005666203.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCT00000042301", "database": "ENSEMBL", "url": "" }, { "id": "XP_020954689.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCG00000001882", "database": "ENSEMBL", "url": "" }, { "id": "XP_013833518.1", "database": "RefSeq", "url": "" }, { "id": "XP_001924578.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9629909", "participant_name": "NEIL1 [cytosol]", "crossref": [ { "id": "A0A4X1TT87", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000001882", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000040249", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000042301", "database": "ENSEMBL", "url": "" }, { "id": "XP_013833516.1", "database": "RefSeq", "url": "" }, { "id": "XP_001924578.1", "database": "RefSeq", "url": "" }, { "id": "XP_020954690.1", "database": "RefSeq", "url": "" }, { "id": "XP_020954689.1", "database": "RefSeq", "url": "" }, { "id": "XP_020954687.1", "database": "RefSeq", "url": "" }, { "id": "XP_013833518.1", "database": "RefSeq", "url": "" }, { "id": "XP_020954688.1", "database": "RefSeq", "url": "" }, { "id": "XP_005666203.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TT87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT87" }, { "id": "PS51068", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51068" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Formamidopyrimidine-DNA glycosylase catalytic", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 121, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TTW2-1", "uniprot_ac": "A0A4X1TTW2", "uniprot_id": "A0A4X1TTW2_PIG", "mass": { "chemical_mass": 32041.0, "monoisotopic_mass": 32041.0 }, "refseq": { "ac": "XP_003122548", "name": "protein YIF1A isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122548" }, "gene_names": [ { "name": "YIF1A", "type": "recommended", "evidence": [ { "id": "A0A4X1TTW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2" } ] }, { "name": "YIF1A", "type": "synonym", "evidence": [ { "id": "XP_003122548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122548" } ] } ], "protein_names": [ { "name": "Protein YIF1", "type": "recommended", "evidence": [ { "id": "A0A4X1TTW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2/entry#names_and_taxonomy" } ] }, { "name": "protein YIF1A isoform X3", "type": "synonym", "evidence": [ { "id": "XP_003122548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122548" } ] } ], "function": [ { "annotation": "Has a role in transport between endoplasmic reticulum and Golgi.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FEK1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEK1#function" }, { "database": "UniProtKB", "id": "RU368073", "url": "https://www.uniprot.org/uniprotkb/RU368073#function" }, { "database": "UniProtKB", "id": "A0A4X1TTT0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT0#function" }, { "database": "UniProtKB", "id": "A0A4X1TTW2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2#function" }, { "database": "UniProtKB", "id": "A0A5G2RKA7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKA7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTW2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "YIF1A", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2", "locus": { "chromosome": "2", "start_pos": 6102037, "end_pos": 6095877, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012953", "url": "https://www.ensembl.org/id/ENSSSCG00000012953" } ] } } ], "crossref": [ { "id": "A0A4X1TTW2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TTW2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012953", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012953", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100521064", "url": "https://www.ncbi.nlm.nih.gov/gene/100521064", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521064", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521064", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NWEVRYS", "url": "https://omabrowser.org/oma/group/NWEVRYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TTT0", "url": "https://www.orthodb.org/?gene=A0A4X1TTT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TTW2", "url": "https://www.orthodb.org/?gene=A0A4X1TTW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14083:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14083:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003122548", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122548", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TTT0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TTT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TTW2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TTW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKA7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RKA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RKA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEK1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FEK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYHSGYGAHGSKHRARAAPDPPSLFDDTSGGYSSQPGGYPAPGADVAFNVNHLLGDPMANVAMAYGSSIASHGKDMVHKELHRFVSVNKLKYFFAVDTAYVAKKLGLLVFPYTHQNWEVQYSRDVPLPPRQDLNAPDLYIPTMAFITYVLLAGMALGIQKRFSPEVLGLCASTALVWVVMEVLALLLGIYLATVRSDLSTFHLLAYSGYKYVGMILSVLTGLLFGSDGYYVALAWTSSALMYFIVRSLRTAALGSDSMGGPAPRQRLQLYLTLGAAAFQPLIIYWLTFHLVR", "length": 293, "header": "tr|A0A4X1TTW2-1|A0A4X1TTW2_PIG Isoform 1 of Protein YIF1 OS=Sus scrofa OX=9823 GN=YIF1A PE=3 SV=1 CANONICAL=A0A4X1TTW2-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TTT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2/entry#A0A4X1TTT0-1", "sequence": { "sequence": "MAYHSGYGAHGSKHRARAAPDPPSLFDDTSGGYSSQPGGYPAPGADVAFNVNHLLGDPMANVAMAYGSSIASHGKDMVHKELHRFVSVNKLKYFFAVDTAYVAKKLGLLVFPYTHQNWEVQYSRDVPLPPRQDLNAPDLYIPTMAFITYVLLAGMALGIQKRMILSVLTGLLFGSDGYYVALAWTSSALMYFIVRSLRTAALGSDSMGGPAPRQRLQLYLTLGAAAFQPLIIYWLTFHLVR", "length": 241, "header": "tr|A0A4X1TTT0-1|A0A4X1TTW2_PIG Computationally mapped isoform of Protein YIF1 OS=Sus scrofa OX=9823 GN=YIF1A PE=3 SV=1 CANONICAL=A0A4X1TTW2-1" }, "locus": { "chromosome": "2", "start_pos": 6101906, "end_pos": 6097949, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014158.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014158.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013772.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013772.3" } ] } }, { "isoform_ac": "A0A4X1TTW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2/entry#A0A4X1TTW2-1", "sequence": { "sequence": "MAYHSGYGAHGSKHRARAAPDPPSLFDDTSGGYSSQPGGYPAPGADVAFNVNHLLGDPMANVAMAYGSSIASHGKDMVHKELHRFVSVNKLKYFFAVDTAYVAKKLGLLVFPYTHQNWEVQYSRDVPLPPRQDLNAPDLYIPTMAFITYVLLAGMALGIQKRFSPEVLGLCASTALVWVVMEVLALLLGIYLATVRSDLSTFHLLAYSGYKYVGMILSVLTGLLFGSDGYYVALAWTSSALMYFIVRSLRTAALGSDSMGGPAPRQRLQLYLTLGAAAFQPLIIYWLTFHLVR", "length": 293, "header": "tr|A0A4X1TTW2-1|A0A4X1TTW2_PIG Isoform 1 of Protein YIF1 OS=Sus scrofa OX=9823 GN=YIF1A PE=3 SV=1 CANONICAL=A0A4X1TTW2-1" }, "locus": { "chromosome": "2", "start_pos": 6101906, "end_pos": 6097949, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055267.2", "url": "https://www.ensembl.org/id/ENSSSCT00000055267.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036812.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036812.1" } ] } }, { "isoform_ac": "A0A5G2RKA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2/entry#A0A5G2RKA7-1", "sequence": { "sequence": "MANVAMAYGSSIASHGKDMVHKELHRFVSVNKLKYFFAVDTAYVAKKLGLLVFPYTHQNWEVQYSRDVPLPPRQDLNAPDLYIPTMAFITYVLLAGMALGIQKRFSPEVLGLCASTALVWVVMEVLALLLGIYLATVRSDLSTFHLLAYSGYKYVGMILSVLTGLLFGSDGYYVALAWTSSALMYFIVSLGRPLFARVRAGDKPPPGPASALLSSRCALCELQPWAPTAWGARPPGSASSST", "length": 242, "header": "tr|A0A5G2RKA7-1|A0A4X1TTW2_PIG Computationally mapped isoform of Protein YIF1 OS=Sus scrofa OX=9823 GN=YIF1A PE=3 SV=2 CANONICAL=A0A4X1TTW2-1" }, "locus": { "chromosome": "2", "start_pos": 6101841, "end_pos": 6098817, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068761.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068761.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072492.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072492.2" } ] } }, { "isoform_ac": "A0A8W4FEK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2/entry#A0A8W4FEK1-1", "sequence": { "sequence": "MANVAMAYGSSIASHGKDMVHKELHRFVSVNKLKYFFAVDTAYVAKKLGLLVFPYTHQNWEVQYSRDVPLPPRQDLNAPDLYIPTMAFITYVLLAGMALGIQKRFSPEVLGLCASTALVWVVMEVLALLLGIYLATVRSDLSTFHLLAYSGYKYVGMILSVLTGLLFGSDGYYVALAWTSSALMYFIVRSLRTAALGSDSMGGPAPRQRLQLYLTLGAAAFQPLIIYWLTFHLVR", "length": 235, "header": "tr|A0A8W4FEK1-1|A0A4X1TTW2_PIG Computationally mapped isoform of Protein YIF1 OS=Sus scrofa OX=9823 GN=YIF1A PE=3 SV=1 CANONICAL=A0A4X1TTW2-1" }, "locus": { "chromosome": "2", "start_pos": 6101906, "end_pos": 6098817, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105578.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105578.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077741.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077741.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FEK1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEK1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521064", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521064", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0BMV4-1", "protein_name": "Protein YIF1", "gene_name": "Yif1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAYHSGYGVHGSKHRTRAAPNPPPLFDDTSGGYSSQLGGYPAPGADVAFNVNNLLGDPVANMAMAYGSSIASQGKDIVHKELHRFVSINKLKYFFAVDTAYVAKKLGLLVFPYTHQNWKVQYSHDVPLPPRKDLNAPDLYIPTMAFITYVLLAGMALGIQQRFSPEVLGLCASTALVWVLMEVLALLLGLYLATVRSELGTFHLLAYSGYKYVGMILSVLTGLLFGSDGYYVALAWTSSALMYFTVRSLRTAASGPDSMGGPTPRQHLQLYLTLGAAAFQPLIIYWLTFHLVR", "length": 293 }, "evidence": [ { "id": "A0A4X1TTW2", "url": "https://omabrowser.org/oma/group/A0A4X1TTW2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4J8C0-1", "protein_name": "Integral membrane HRF1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYNNMGPRPGMAMPQANPQPSPFGNPFSGPGSGLIRSGLGAYGEKIFGSSSEYVQSNISRYFSDPQYYFQVNDQYVRNKLKIVLLPFLHRGHWTRISEPVGGRLSYKPPIYDINAPDLYIPLMAFGTYVVLAGLSLGLYGKFTPEALNWLFVKGMVGWFLQVMLLKITLLSLGSGEAPLLDIVAYAGYTFTGLCLAVLGKIIWGYSYYVLIPWTCLCTGVFLVKTMKRVLFAESRSYDSSRHHYLLIFVALAQFPLLIWLGNISVNWLF", "length": 269 }, "evidence": [ { "id": "A0A4X1TTW2", "url": "https://omabrowser.org/oma/group/A0A4X1TTW2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3I2E7-1", "protein_name": "Protein YIF1", "gene_name": "Yif1a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAYHSGYGAHGSKHRTRAAPDSPPLFDDTSGGYSSHPGGYPAPGADVAFSVNHLLGDPVANMAMAYGSSIASQGKDIVHKELHRFVSVNKLKYFFAVDTAYVAKKLGLLVFPYTHQNWKMQYSHDVPLPPRKDLNAPDLYIPTMAFITYVLLAGTALGIQKRFSPEVLGLCASTALVWVFMEVLALLLGLYLATVRSELSTFHLLAYSGYKYVGMILSVITGLLFGSDGYYVALAWTSSALMYFIVRSLRTAALGPDSMGGPAPGQRLQLYLTLGAAAFQPLIIYWLTFHLVR", "length": 293 }, "evidence": [ { "id": "A0A4X1TTW2", "url": "https://omabrowser.org/oma/group/A0A4X1TTW2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95070-1", "protein_name": "Protein YIF1A", "gene_name": "YIF1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAYHSGYGAHGSKHRARAAPDPPPLFDDTSGGYSSQPGGYPATGADVAFSVNHLLGDPMANVAMAYGSSIASHGKDMVHKELHRFVSVSKLKYFFAVDTAYVAKKLGLLVFPYTHQNWEVQYSRDAPLPPRQDLNAPDLYIPTMAFITYVLLAGMALGIQKRFSPEVLGLCASTALVWVVMEVLALLLGLYLATVRSDLSTFHLLAYSGYKYVGMILSVLTGLLFGSDGYYVALAWTSSALMYFIVRSLRTAALGPDSMGGPVPRQRLQLYLTLGAAAFQPLIIYWLTFHLVR", "length": 293 }, "evidence": [ { "id": "A0A4X1TTW2", "url": "https://omabrowser.org/oma/group/A0A4X1TTW2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3T196-1", "protein_name": "Protein YIF1A", "gene_name": "YIF1A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAYHSGYGAHGSKHRARAAPDPPPLFDDTSGGYSSQPGGYPAPGADVAFNVNHLLGDPMANMAMAYGSSIASHGKDMMNKELHRFVSVNKLKYFFAVDTAYVAKKLGLLVFPYTHQNWEVQYSRDVPLPPRQDLNAPDLYIPTMAFITYVLLAGMALGIQKRFSPEVLGLCASTALVWVVMEVLALLLGIYLATVRSDLSTFHLLAYSGYKYVGMILSVLTGLLFGSDGYYVALAWTSSALMYFIVRSLRTAALGPDSMGGPAPRQRLQLYLTLGAAAFQPLIIYWLTFHLVR", "length": 293 }, "evidence": [ { "id": "A0A4X1TTW2", "url": "https://omabrowser.org/oma/group/A0A4X1TTW2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54XV4-1", "protein_name": "Protein YIF1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHNLGYMEYNKGNTGYNSGENYPSMDQYNYGQGNMGNMGNMGQQYQPPQQQQQPPQQQQQHNSGFGFPSPTLYNMNAQQQQQQQQQHQQQQHHNQQTSPMYGNNGGFNQFNNNDNSHYSPPQQGDMSRQFISQISDNPLTQAGLTYGLNYGQTLFSGGKQYVDSNFGKYFSFSTLKSYFNVNNSYVFNKIKLLIFPYTQKTWKRRIGRTSDVDSYLPPRDDINAPDLYIPLMAFITYFLLYGFQMGMEKKFSPDYLGACITKGIVFWAIELLIFKCGFFFSNSNSIPFYDMISYSGYKYVLMVIFQIATILLGSYVSYIIKCVLSVSIAFFMLKTLRLVFSSVSGAHDHISPDYHESGKIKNYFVFGFSVAQALLCFLV", "length": 380 }, "evidence": [ { "id": "A0A4X1TTW2", "url": "https://omabrowser.org/oma/group/A0A4X1TTW2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6PC24-1", "protein_name": "Protein YIF1A", "gene_name": "yif1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNFQQQGYRATKPRARASPPTGGPMLFDDTSSGPPPMNNQNYYSSGYNMAEMPAGGQEPGVGNIFADPMANAAMMYGSTLANQGKDIVNKEINRFMSVNKLKYFFAVDTKYVMKKLLLLMFPYTHQDWEVRYHRDTPLTPRHDVNAPDLYIPTMAFITYILLAGMALGIQKRFSPEVLGLCASTALVWMIIEVLVMLLSLYLLTVHTDLSTFDLVAYSGYKYVGMILTVFCGLLFGSDGYYVALAWSSCALMFFIVRSLKMKILSSISADSMGAGASAKPRFRLYITVASAAFQPFIIYWLTAHLVR", "length": 307 }, "evidence": [ { "id": "A0A4X1TTW2", "url": "https://omabrowser.org/oma/group/A0A4X1TTW2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q91XB7-1", "protein_name": "Protein YIF1A", "gene_name": "Yif1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAYHSAYGVHGSKHRTRAAPDPPPLFDDTSGGYSSQLGGYPAPGADVAFSVNNLLGDPVANMAMAYGTSIASQGKDIVHKELHRFVSVNKLKYFFAVDTAYVAKKLGLLVFPYTHQNWKMQYSHDVPLPPRKDLNAPDLYIPTMAFITYVLLAGMALGIQQRFSPEVLGLCASTALVWVFMEVLALLLGLYLATVRSELSTFHLLAYSGYKYVGMILSVLTGLLFGSDGYYVALAWTSSALMYFIVRSLRTAASGPDSMGGPAPRQRLQLYLTLGAAAFQPLIIYWLTFHLVR", "length": 293 }, "evidence": [ { "id": "A0A4X1TTW2", "url": "https://omabrowser.org/oma/group/A0A4X1TTW2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTW2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTW2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTW2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTW2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTW2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TTW2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TTW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TUP2-1", "uniprot_ac": "A0A4X1TUP2", "uniprot_id": "A0A4X1TUP2_PIG", "mass": { "chemical_mass": 46697.0, "monoisotopic_mass": 46697.0 }, "refseq": { "ac": "XP_001927223", "name": "protein ZNF365", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927223" }, "gene_names": [ { "name": "ZNF365", "type": "recommended", "evidence": [ { "id": "A0A4X1TUP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ] }, { "name": "ZNF365", "type": "synonym", "evidence": [ { "id": "XP_001927223", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927223" } ] } ], "protein_names": [ { "name": "Zinc finger protein 365", "type": "synonym", "evidence": [ { "id": "A0A4X1TUP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2/entry#names_and_taxonomy" } ] }, { "name": "protein ZNF365", "type": "synonym", "evidence": [ { "id": "XP_001927223", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927223" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF365", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2", "locus": { "chromosome": "14", "start_pos": 65888335, "end_pos": 65861564, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010222", "url": "https://www.ensembl.org/id/ENSSSCG00000010222" } ] } } ], "crossref": [ { "id": "A0A4X1TUP2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TUP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100157357", "url": "https://www.ncbi.nlm.nih.gov/gene/100157357", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157357", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157357", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNHADLK", "url": "https://omabrowser.org/oma/group/CNHADLK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TUP2", "url": "https://www.orthodb.org/?gene=A0A4X1TUP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15739", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15739", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15739:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15739:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23165", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23165", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001927223", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927223", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TUP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYQERTLLTKCSIFPSIKDTDLVTSSEPLKQGKLQSCGNIVKQRPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAVDLRADSLDGPRSSPGLPTSDTKAAFEAHVREKFNQMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAALRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLHRVELAEKQLEYYHGQHAAGLHWDTSEHGLTDIASNRKPKCLSRGHPHSMCNHPDLKIHFHPKGRSYLKKAKDDRASMQPAKCMHEQAESPRDLCRPAKKGEPLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407, "header": "tr|A0A4X1TUP2-1|A0A4X1TUP2_PIG Isoform 1 of Zinc finger protein 365 OS=Sus scrofa OX=9823 GN=ZNF365 PE=4 SV=1 CANONICAL=A0A4X1TUP2-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TUP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2/entry#A0A4X1TUP2-1", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYQERTLLTKCSIFPSIKDTDLVTSSEPLKQGKLQSCGNIVKQRPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAVDLRADSLDGPRSSPGLPTSDTKAAFEAHVREKFNQMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAALRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLHRVELAEKQLEYYHGQHAAGLHWDTSEHGLTDIASNRKPKCLSRGHPHSMCNHPDLKIHFHPKGRSYLKKAKDDRASMQPAKCMHEQAESPRDLCRPAKKGEPLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407, "header": "tr|A0A4X1TUP2-1|A0A4X1TUP2_PIG Isoform 1 of Zinc finger protein 365 OS=Sus scrofa OX=9823 GN=ZNF365 PE=4 SV=1 CANONICAL=A0A4X1TUP2-1" }, "locus": { "chromosome": "14", "start_pos": 65885537, "end_pos": 65863306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011188.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011188.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010897.2", "url": "https://www.ensembl.org/id/ENSSSCP00000010897.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157357", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157357", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y3Z0-1", "protein_name": "Zinc finger protein 365", "gene_name": "ZNF365", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQQDAAEQSGFPWQDALGDASLRLPFRCPRCGERSRFRSLSALRAHLEYGHGYEERSVPPKGGPPSPRKGAGPASPPEPCGPGSATRYAPCAGFCDASSGSAEGRRALEAERGPVCCLAGYAPAGSPGSRLSSPVLPAADSKASFEAHVREKFNRMVEAVDKTIEKRIDKLTKELAQKTAELLEVRAAFVQLSQKKQEVQRRERALSRQVDVAVEMIAALKQRLTESEEELHRKEEEVVTFNHFLEEAAEKEVRGKARLQHFIENLLQRVDLAERQLEYYQNQQIACNHTGGSDHVVSQQSSFINCHPPLRGKCSASNFTDISSNKKPRCLSRGSQHTSYNIPDTKPHSFQKGRGLLKKAKEEKTSLQPVRCFYEPVDCPREIWRAQKKGEPVCSARKLSAKSKMGKKTKQL", "length": 412 }, "evidence": [ { "id": "A0A4X1TUP2", "url": "https://omabrowser.org/oma/group/A0A4X1TUP2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BB98-1", "protein_name": "Zinc finger protein 365", "gene_name": "ZNF365", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYQERTLLTKCSLFPSLKDTDLVTSSEPPKQGKLQSCGNIVKQKPSYVNLYSISHEHSKDRKPFEMVAERPVSYVQTYTTVDLRADSPDAPRASPGLPAPDTKAAFEAHVREKFSRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAALRQRLTESEEELLRKEEEVVTFNHFLETAAEKEVQGKARLQDFIENLLHRVELAEKQLEYYHSRQGAGPCGDPREHALTDISSNRKPKYLSRGHLHSVYNHPDLKTHFHPKGRMKKAKDDRASVQPAKSLHEQTESPRELCRPAKKGEPLGFGRKGNIRPKMAKKKPTAIVNII", "length": 405 }, "evidence": [ { "id": "A0A4X1TUP2", "url": "https://omabrowser.org/oma/group/A0A4X1TUP2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5PQS2-1", "protein_name": "Protein ZNF365", "gene_name": "Znf365", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQQTTFEESRYRWQDSLENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLLPSLKDTDLLRSSELPKQGKLLRGHAKVTKQKPSYVNLYSISHGHSKDPKPFEMVAERPVSYVQTYTAVDIRADSLDAPRSSSGLPTQDTKAAFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALHKQVDVAVEMIAVLKQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFSHDTSEHMLTDISSSRKSRCLSRGHQHSVCNHPELKAHFHLKGRSYLKKAKDERAGMQPAKAIHEQAESPREFFRPAKKGEHLGLSRKGNFRPKMAKKKPTAIVNII", "length": 408 }, "evidence": [ { "id": "A0A4X1TUP2", "url": "https://omabrowser.org/oma/group/A0A4X1TUP2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A4X1TUP2", "url": "https://omabrowser.org/oma/group/A0A4X1TUP2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BG89-1", "protein_name": "Protein ZNF365", "gene_name": "Znf365", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQQTTFEESRYHWQDSLENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLLPSLKDTELLRSSELPKQGKVLRGHAKVTKQKSSYVNLYSISHGHSKDTKPFEMVAERPVSYVQTYTAVDIRADSLDAPCASPGLPTQDTKAAFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFAQLTQKKQEVQRRERALNKQVDVAVEMIAVLKQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFSCDTSEHMLTDIPSNRKPRCLSRGHQHSVCNHPEMRAHFHLKGRSYLKKAKDERAGMQPAKAIHEPAESPREFFRPAKKGEHLGLSRKGNFRPKMAKKKPTAIVNII", "length": 408 }, "evidence": [ { "id": "A0A4X1TUP2", "url": "https://omabrowser.org/oma/group/A0A4X1TUP2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "positive regulation of oligodendrocyte differentiation", "id": "GO:0048714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048714", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ], "pmid": "" }, { "name": "dendrite arborization", "id": "GO:0140059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140059", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ], "pmid": "" }, { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ], "pmid": "" }, { "name": "regulation of neuron projection development", "id": "GO:0010975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010975", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ], "pmid": "" }, { "name": "dendritic spine morphogenesis", "id": "GO:0060997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060997", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ], "pmid": "" }, { "name": "cerebellar molecular layer morphogenesis", "id": "GO:0021687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021687", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ], "pmid": "" }, { "name": "regulation of DNA strand resection involved in replication fork processing", "id": "GO:0110026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110026", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ], "pmid": "" }, { "name": "regulation of double-strand break repair via homologous recombination", "id": "GO:0010569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010569", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUP2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TUP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUP2" }, { "id": "PF23165", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23165" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FBX41/ZN365 C2H2-type zinc finger", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 53, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TUW4-1", "uniprot_ac": "A0A4X1TUW4", "uniprot_id": "A0A4X1TUW4_PIG", "mass": { "chemical_mass": 44965.0, "monoisotopic_mass": 44965.0 }, "refseq": { "ac": "XP_020955210", "name": "serpin B13 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955210" }, "gene_names": [ { "name": "SERPINB13", "type": "recommended", "evidence": [ { "id": "A0A4X1TUW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4" } ] }, { "name": "SERPINB13", "type": "synonym", "evidence": [ { "id": "XP_020955210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955210" } ] } ], "protein_names": [ { "name": "Serpin B13", "type": "recommended", "evidence": [ { "id": "A0A4X1TUW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4/entry#names_and_taxonomy" } ] }, { "name": "serpin B13 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020955210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955210" } ] } ], "function": [ { "annotation": "May play a role in the proliferation or differentiation of keratinocytes.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUW4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4#function" }, { "database": "UniProtKB", "id": "ARBA00055143", "url": "https://www.uniprot.org/uniprotkb/ARBA00055143#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUW4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SERPINB13", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4", "locus": { "chromosome": "1", "start_pos": 158099975, "end_pos": 158113501, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034519", "url": "https://www.ensembl.org/id/ENSSSCG00000034519" } ] } } ], "crossref": [ { "id": "A0A4X1TUW4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TUW4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19572", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19572", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110261638", "url": "https://www.ncbi.nlm.nih.gov/gene/110261638", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110261638", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261638", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TUW4", "url": "https://www.orthodb.org/?gene=A0A4X1TUW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461:SF161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461:SF161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8939242", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939242", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020955210", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955210", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TUW4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TUW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSLILANTRFGFNLFKELSQMNDRNIFFSPEGIKTAIGMFLLGAHGATAAQLWKVLFSEKDTESSRIKLEEKEIEKTEDIHHQFQRFLNEISKPTNDYGLKISNRLFGEKTYLFLQKYLDYVEKYYHASLEPVDFVNATDESRKKINSWVESRTNEKIKDLLPDGSLSSSTKLVAVNVVYFKGQWDREFEKENTKEEEFWLNKSTSRSVLMMTQRQLFGFMVLEDLQAKILGIPYKNNDLSMFVLLPNDIDGLEKIIDKITPEKLIEWTNPGHLEERNVDLRLPRFEVEDSYDLEAVLESMGVADAFSEQEASYSEMFSLSGLRAQKFLHRSFAEVTEEGIEAAAGTGVGFAVTFAPGYENFHCNHPFLFFIRHNESNSILFFGRFSSP", "length": 390, "header": "tr|A0A4X1TUW4-1|A0A4X1TUW4_PIG Isoform 1 of Serpin B13 OS=Sus scrofa OX=9823 GN=SERPINB13 PE=3 SV=1 CANONICAL=A0A4X1TUW4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TUW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4/entry#A0A4X1TUW4-1", "sequence": { "sequence": "MDSLILANTRFGFNLFKELSQMNDRNIFFSPEGIKTAIGMFLLGAHGATAAQLWKVLFSEKDTESSRIKLEEKEIEKTEDIHHQFQRFLNEISKPTNDYGLKISNRLFGEKTYLFLQKYLDYVEKYYHASLEPVDFVNATDESRKKINSWVESRTNEKIKDLLPDGSLSSSTKLVAVNVVYFKGQWDREFEKENTKEEEFWLNKSTSRSVLMMTQRQLFGFMVLEDLQAKILGIPYKNNDLSMFVLLPNDIDGLEKIIDKITPEKLIEWTNPGHLEERNVDLRLPRFEVEDSYDLEAVLESMGVADAFSEQEASYSEMFSLSGLRAQKFLHRSFAEVTEEGIEAAAGTGVGFAVTFAPGYENFHCNHPFLFFIRHNESNSILFFGRFSSP", "length": 390, "header": "tr|A0A4X1TUW4-1|A0A4X1TUW4_PIG Isoform 1 of Serpin B13 OS=Sus scrofa OX=9823 GN=SERPINB13 PE=3 SV=1 CANONICAL=A0A4X1TUW4-1" }, "locus": { "chromosome": "1", "start_pos": 158111946, "end_pos": 158100175, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050888.2", "url": "https://www.ensembl.org/id/ENSSSCT00000050888.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045405.1", "url": "https://www.ensembl.org/id/ENSSSCP00000045405.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUW4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110261638", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261638", "resource": "KEGG Pathway" }, { "id": "R-SSC-8939242", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939242", "resource": "Reactome", "description": "RUNX1 regulates transcription of genes involved in differentiation of keratinocytes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUW4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4" } ], "pmid": "" }, { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUW4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase inhibitor activity", "id": "GO:0004869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004869", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUW4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUW4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUW4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUW4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of keratinocyte apoptotic process", "id": "GO:1902173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902173", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUW4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TUW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUW4" }, { "id": "SM00093", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serpin", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 390, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 376, "end_pos": 378 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TUX1-1", "uniprot_ac": "A0A4X1TUX1", "uniprot_id": "A0A4X1TUX1_PIG", "mass": { "chemical_mass": 47393.0, "monoisotopic_mass": 47393.0 }, "refseq": {}, "gene_names": [ { "name": "ZC3H15", "type": "recommended", "evidence": [ { "id": "A0A4X1TUX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH domain-containing protein 15", "type": "recommended", "evidence": [ { "id": "A0A4X1TUX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZC3H15", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1", "locus": { "chromosome": "15", "start_pos": 91518760, "end_pos": 91493713, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000055460", "url": "https://www.ensembl.org/id/ENSSSCG00000055460" } ] } } ], "crossref": [ { "id": "A0A4X1TUX1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TUX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100158058", "url": "https://www.ncbi.nlm.nih.gov/gene/100158058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100158058", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158058", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GREMFYF", "url": "https://omabrowser.org/oma/group/GREMFYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TY43", "url": "https://www.orthodb.org/?gene=A0A4X1TY43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12681", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12681", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12681:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12681:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16543", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16543", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9629569", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9629569", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TUX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TUX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TY43", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TY43-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LPPQKNPELNASSYADKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDIERRKADFKAGKALVISGREVFEFRPELVDDDDEEADDTRYTQGTGCDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTSEKDENKLSEASGGKAENGERSDLEEDNEGEGQENGAIDAVPVDENLFTGEDLDELEEELNTLDLEE", "length": 416, "header": "tr|A0A4X1TUX1-1|A0A4X1TUX1_PIG Isoform 1 of Zinc finger CCCH domain-containing protein 15 OS=Sus scrofa OX=9823 GN=ZC3H15 PE=1 SV=1 CANONICAL=A0A4X1TUX1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TUX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1/entry#A0A4X1TUX1-1", "sequence": { "sequence": "LPPQKNPELNASSYADKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDIERRKADFKAGKALVISGREVFEFRPELVDDDDEEADDTRYTQGTGCDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTSEKDENKLSEASGGKAENGERSDLEEDNEGEGQENGAIDAVPVDENLFTGEDLDELEEELNTLDLEE", "length": 416, "header": "tr|A0A4X1TUX1-1|A0A4X1TUX1_PIG Isoform 1 of Zinc finger CCCH domain-containing protein 15 OS=Sus scrofa OX=9823 GN=ZC3H15 PE=1 SV=1 CANONICAL=A0A4X1TUX1-1" }, "locus": { "chromosome": "15", "start_pos": 91516744, "end_pos": 91502179, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104336.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104336.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078702.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078702.1" } ] } }, { "isoform_ac": "A0A4X1TY43-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1/entry#A0A4X1TY43-1", "sequence": { "sequence": "MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDIERRKADFKAGKALVISGREVFEFRPELVDDDDEEADDTRYTQGTGCDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTSEKDENKLSEASGGKAENGERSDLEEDNEGEGQENGAIDAVPVDENLFTGEDLDELEEELNTLDLEE", "length": 426, "header": "tr|A0A4X1TY43-1|A0A4X1TY43_PIG Computationally mapped isoform of Zinc finger CCCH domain-containing protein 15 OS=Sus scrofa OX=9823 GN=ZC3H15 PE=1 SV=1 CANONICAL=A0A4X1TUX1-1" }, "locus": { "chromosome": "15", "start_pos": 91516744, "end_pos": 91493764, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017451.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017451.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016981.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016981.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100158058", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158058", "resource": "KEGG Pathway" }, { "id": "R-SSC-9629569", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9629569", "resource": "Reactome", "description": "Protein hydroxylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PMI7-1", "protein_name": "Zinc finger CCCH domain-containing protein 15", "gene_name": "ZC3H15", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPPKKQQQPAGSSKKADQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQAAQTESEKKLKKEDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLSLERKCEKRSVYIDARDEDLEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKYFLDAIENNKYGWFWVCPGGGDNCMYRHALPPGFVLKKDKKKEEKQDEISLEDLIEKERAALGPNVTKITLECFIAWKRRKRQEKIDKAEQDMERRKADFKAGKALVISGREVFEFRPELVDADDEEADDTRYTQGTGEDDEVEDPVCVNDVDLSLYVPKAVDETGITVASPERFSTYASIEKDDNKLSEASGGEINSSEQNDLEDRDGDEELENGVMDAVPVDENLFTGEDLDELEEELNTLDLEE", "length": 429 }, "evidence": [ { "id": "A0A4X1TUX1", "url": "https://omabrowser.org/oma/group/A0A4X1TUX1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q12000-1", "protein_name": "Translation machinery-associated protein 46", "gene_name": "TMA46", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPPKKGKQAQAAGKKKDNVDKTFGMKNKNRSTKVQKYIKQVQSQSDPKKEEMRLKKLEEKKRREAEEAERRALFNPVADQRVRAGVDPKSMVCALFKLGNCNKGAKCKFSHDLNVGRRMEKKDLYQDTRSEKENDTMDNWDEEKLRKVILSKHGNPKTTTDKVCKYFIEAVENGKYGWFWICPNGGDKCMYRHSLPEGFVLKTNEQKRLERESLEKQPKITLEEFIETERGKLDKSKLTPITIANFAQWKKDHVIAKINAEKKLSSKRKPTGREIILKMSAENKSFETDNADMPDDVTQGSAWDLTEFTDALKKADHQDDGGIKDYGDGSNPTFDIKKANSATLA", "length": 345 }, "evidence": [ { "id": "A0A4X1TUX1", "url": "https://omabrowser.org/oma/group/A0A4X1TUX1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q1RMM1-1", "protein_name": "Zinc finger CCCH domain-containing protein 15", "gene_name": "ZC3H15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDIERRKADFKAGKALVISGREVFEFRPELVDDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTSEKDENKLSEASGGRAENGERSDLEEDNEGEGQENGAIDAVPVDENLFTGEDLDELEEELNTLDLEE", "length": 426 }, "evidence": [ { "id": "A0A4X1TUX1", "url": "https://omabrowser.org/oma/group/A0A4X1TUX1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TIV5-1", "protein_name": "Zinc finger CCCH domain-containing protein 15", "gene_name": "Zc3h15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCRHFLEAIENNKYGWFWVCPGGGDNCMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYIQGTGGDEVDDSMGVNDIDISLYVPRDVEETGITVASVERFSTYAPDKDENKLSEASGGLAENGERSDLDEDSGGGGQENGSIDAVPVDENLFTGEDLDELEEELNTLDLEE", "length": 426 }, "evidence": [ { "id": "A0A4X1TUX1", "url": "https://omabrowser.org/oma/group/A0A4X1TUX1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54DA5-1", "protein_name": "Zinc finger CCCH domain-containing protein 15 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPKQAQSKKTVEKEKKKKVEDKTFGLKNKNKSKKVAAYVSQVEAQVKHSGLQNKEAALKEKAKRDKELAEKAKKEAESILVNTIVQSKVPLGVDPKSIVCEYFKQGVTCPKGNRCKFAHDLAAGRKSEKIDIYTDRRKDEDTMENWDEAKLKSVVEKKRTTENKAKPTAIICKFFLDAIESKKYGWFWECPNGGEKCAYQHCLPEGYQLKKKKSREEDEVEEIPIEELIEEERAKLTKSTPVTLETFLRWKEEKRLQKEKAAKDAQDKRLADIKAGKTSMSGREMFVFNPDLFVDDESAIDTKSKEYEKSEEEIAALANQINTSLFTDGGVLPSDDDDDDDDDDDDDEDGDDEEEDDDEEEGEYEEEEASDE", "length": 373 }, "evidence": [ { "id": "A0A4X1TUX1", "url": "https://omabrowser.org/oma/group/A0A4X1TUX1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6U6G5-1", "protein_name": "Zinc finger CCCH domain-containing protein 15", "gene_name": "Zc3h15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCRHFLEAIENNKYGWFWVCPGGGDNCMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYIQGTGGDEVDDSVGVNDIDLSLYVPRDVEETGITVASLERFSTYASDKDENKLSEASGGLAENGERSDLDEDSGGGGQENGSIDAVPVDENLFTGEDLDELEEELNTLDLEE", "length": 426 }, "evidence": [ { "id": "A0A4X1TUX1", "url": "https://omabrowser.org/oma/group/A0A4X1TUX1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WU90-1", "protein_name": "Zinc finger CCCH domain-containing protein 15", "gene_name": "ZC3H15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTSDKDENKLSEASGGRAENGERSDLEEDNEREGTENGAIDAVPVDENLFTGEDLDELEEELNTLDLEE", "length": 426 }, "evidence": [ { "id": "A0A4X1TUX1", "url": "https://omabrowser.org/oma/group/A0A4X1TUX1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TUX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TUX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TUX1" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 116, "start_aa": "Asp", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 236, "end_pos": 238 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TV12-1", "uniprot_ac": "A0A4X1TV12", "uniprot_id": "A0A4X1TV12_PIG", "mass": { "chemical_mass": 38064.0, "monoisotopic_mass": 38064.0 }, "refseq": { "ac": "XP_003354452", "name": "olfactory receptor 14A16-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354452" }, "gene_names": [ { "name": "LOC100623897", "type": "recommended", "evidence": [ { "id": "A0A4X1TV12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12" } ] }, { "name": "LOC100623897", "type": "synonym", "evidence": [ { "id": "XP_003354452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354452" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TV12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 14A16-like", "type": "synonym", "evidence": [ { "id": "XP_003354452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354452" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TV12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TV12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TV12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100623897", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12", "locus": {} } ], "crossref": [ { "id": "A0A4X1TV12", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TV12", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15227", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15227", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100623897", "url": "https://www.ncbi.nlm.nih.gov/gene/100623897", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623897", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623897", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YGLIMNW", "url": "https://omabrowser.org/oma/group/YGLIMNW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TV12", "url": "https://www.orthodb.org/?gene=A0A4X1TV12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003354452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354452", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TV12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TV12-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANLTMSVTEFTLMGFSDIWEQQVLHAVLFLLIYLTALVDNFLIVLLTTLDQHLHSPMHFFLRTLSLLDICFISVTVPKAIIQSLTQNSSISFLGCVAQVFLVVSFACAELALLTVMSYDRYVAICQPLHYQVIMKKAHCEQMVFASWLSGIISGFLNTSVTFSLPFCRSNFVHQFFCEIPSLLKLSCSEKYLAEIGAIIVTTSLGIICFISILVSYKQIFSTVMRIPSVKSRSKAFSTCIPHLVVVTVFLNTGSIAYLKPVSESPSVCDLMVSVFYTVVPPTLNPIIYSLKNKDMKAAFSKMLKRLSSYIMTRKTTTKTHTVPSDKHEATSVNSNRLPAI", "length": 341, "header": "tr|A0A4X1TV12-1|A0A4X1TV12_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100623897 PE=3 SV=1 CANONICAL=A0A4X1TV12-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TV12-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12/entry#A0A4X1TV12-1", "sequence": { "sequence": "MANLTMSVTEFTLMGFSDIWEQQVLHAVLFLLIYLTALVDNFLIVLLTTLDQHLHSPMHFFLRTLSLLDICFISVTVPKAIIQSLTQNSSISFLGCVAQVFLVVSFACAELALLTVMSYDRYVAICQPLHYQVIMKKAHCEQMVFASWLSGIISGFLNTSVTFSLPFCRSNFVHQFFCEIPSLLKLSCSEKYLAEIGAIIVTTSLGIICFISILVSYKQIFSTVMRIPSVKSRSKAFSTCIPHLVVVTVFLNTGSIAYLKPVSESPSVCDLMVSVFYTVVPPTLNPIIYSLKNKDMKAAFSKMLKRLSSYIMTRKTTTKTHTVPSDKHEATSVNSNRLPAI", "length": 341, "header": "tr|A0A4X1TV12-1|A0A4X1TV12_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100623897 PE=3 SV=1 CANONICAL=A0A4X1TV12-1" }, "locus": { "chromosome": "2", "start_pos": 53306174, "end_pos": 53305152, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025695.3", "url": "https://www.ensembl.org/id/ENSSSCT00000025695.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028170.2", "url": "https://www.ensembl.org/id/ENSSSCP00000028170.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TV12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623897", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623897", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TV12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TV12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TV12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TV12", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TV12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TV12" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 289, "start_aa": "Asp", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TVG1-1", "uniprot_ac": "A0A4X1TVG1", "uniprot_id": "A0A4X1TVG1_PIG", "mass": { "chemical_mass": 35722.0, "monoisotopic_mass": 35722.0 }, "refseq": { "ac": "XP_003123634", "name": "olfactory receptor 2L8-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123634" }, "gene_names": [ { "name": "LOC100521607", "type": "recommended", "evidence": [ { "id": "A0A4X1TVG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1" } ] }, { "name": "LOC100521607", "type": "synonym", "evidence": [ { "id": "XP_003123634", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123634" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TVG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2L8-like", "type": "synonym", "evidence": [ { "id": "XP_003123634", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123634" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVG1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVG1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100521607", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1", "locus": {} } ], "crossref": [ { "id": "A0A4X1TVG1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TVG1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521607", "url": "https://www.ncbi.nlm.nih.gov/gene/100521607", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521607", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521607", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGNYNQT", "url": "https://omabrowser.org/oma/group/MGNYNQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TVG1", "url": "https://www.orthodb.org/?gene=A0A4X1TVG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003123634", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123634", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TVG1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TVG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKYNQTSTDFILLGLLPPERIGFFLFILIVLIFLMTLFGNLSMILLIILDTQLHTPMYFLLSQLSFMDLNYISTIVPKMAYNYLIGNKSISFIGCGVQSFFFLTLGGAEALILAAMAYDRYVAICFPLHYPIRISRRVCVLMIMGSWIMGSINSCAHTIYILHIPYCRSRAINHFFCDVPAMLTLACMDTWIHEYTVFVSTILFLLLPFIGIACSYGRVLLAVYHMRSDEGKKKAYSTCSTHLTVVTFYYAPFAYTYLRPKFLRAPTEDKALAVFYTILTPILNPLIYSLRNKEVMGALRRVTQRICSVKM", "length": 312, "header": "tr|A0A4X1TVG1-1|A0A4X1TVG1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100521607 PE=3 SV=1 CANONICAL=A0A4X1TVG1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TVG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1/entry#A0A4X1TVG1-1", "sequence": { "sequence": "MEKYNQTSTDFILLGLLPPERIGFFLFILIVLIFLMTLFGNLSMILLIILDTQLHTPMYFLLSQLSFMDLNYISTIVPKMAYNYLIGNKSISFIGCGVQSFFFLTLGGAEALILAAMAYDRYVAICFPLHYPIRISRRVCVLMIMGSWIMGSINSCAHTIYILHIPYCRSRAINHFFCDVPAMLTLACMDTWIHEYTVFVSTILFLLLPFIGIACSYGRVLLAVYHMRSDEGKKKAYSTCSTHLTVVTFYYAPFAYTYLRPKFLRAPTEDKALAVFYTILTPILNPLIYSLRNKEVMGALRRVTQRICSVKM", "length": 312, "header": "tr|A0A4X1TVG1-1|A0A4X1TVG1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100521607 PE=3 SV=1 CANONICAL=A0A4X1TVG1-1" }, "locus": { "chromosome": "2", "start_pos": 55278773, "end_pos": 55277838, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071167.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071167.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069478.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069478.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVG1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521607", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521607", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LKI2-1", "protein_name": "Olfactory receptor", "gene_name": "OR2L2C", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGNYNQTSTDFILLGLFPSSRTGLFLFILIGFIFLMALVGNLSMILLIFLDIRLHKPMYFLLSQLSLMDLNYISTTVPKMAYDFLFANKSISIIGCGIQSFFFLTMACAEGLLLASMAYDRYVAICFPLHYPIRISRKVCILMITGSWIMGSINSCAHTTYILSIPYCQSRSINHFFCDVTVMLTIACIDITVYEYTVFLSTTLFLLLPFIGIAFSYGRVLLAVYCMNSAEGKKKAYSTCSTHLTVVSFYYAPFVYTYLRPRFLRTPTEDKVLAVFYIILTPMLNPIIYSLRNKEVIGALRRVTQRISPMKM", "length": 312 }, "evidence": [ { "id": "A0A4X1TVG1", "url": "https://omabrowser.org/oma/group/A0A4X1TVG1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVG1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVG1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVG1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVG1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TVG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVG1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TVT7-1", "uniprot_ac": "A0A4X1TVT7", "uniprot_id": "A0A4X1TVT7_PIG", "mass": { "chemical_mass": 24606.0, "monoisotopic_mass": 24606.0 }, "refseq": { "ac": "XP_020948215", "name": "zinc finger CCHC-type and RNA-binding motif-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948215" }, "gene_names": [ { "name": "ZCRB1", "type": "recommended", "evidence": [ { "id": "A0A4X1TVT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7" } ] }, { "name": "ZCRB1", "type": "synonym", "evidence": [ { "id": "XP_020948215", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948215" } ] } ], "protein_names": [ { "name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A4X1TVT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7/entry#names_and_taxonomy" } ] }, { "name": "U11/U12 small nuclear ribonucleoprotein 31 kDa protein", "type": "synonym", "evidence": [ { "id": "A0A4X1TVT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCHC-type and RNA-binding motif-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_020948215", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948215" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZCRB1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7", "locus": { "chromosome": "5", "start_pos": 73538985, "end_pos": 73556233, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034066", "url": "https://www.ensembl.org/id/ENSSSCG00000034066" } ] } } ], "crossref": [ { "id": "A0A4X1TVT7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TVT7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12393", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12393", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100624066", "url": "https://www.ncbi.nlm.nih.gov/gene/100624066", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624066", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624066", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHYFNDE", "url": "https://omabrowser.org/oma/group/AHYFNDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TVT7", "url": "https://www.orthodb.org/?gene=A0A4X1TVT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46259", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46259", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46259:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46259:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020948215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948215", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TVT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TVT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKIPEPEEEIEEVEESDDEGEDPALDSLSQAIAFQQAKIEEEQRKWKPSSGGPSTSDDSRRPRIKKSTYFSDEEELSD", "length": 217, "header": "tr|A0A4X1TVT7-1|A0A4X1TVT7_PIG Isoform 1 of Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Sus scrofa OX=9823 GN=ZCRB1 PE=4 SV=1 CANONICAL=A0A4X1TVT7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TVT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7/entry#A0A4X1TVT7-1", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKIPEPEEEIEEVEESDDEGEDPALDSLSQAIAFQQAKIEEEQRKWKPSSGGPSTSDDSRRPRIKKSTYFSDEEELSD", "length": 217, "header": "tr|A0A4X1TVT7-1|A0A4X1TVT7_PIG Isoform 1 of Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Sus scrofa OX=9823 GN=ZCRB1 PE=4 SV=1 CANONICAL=A0A4X1TVT7-1" }, "locus": { "chromosome": "5", "start_pos": 73554806, "end_pos": 73539494, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044401.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044401.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049793.1", "url": "https://www.ensembl.org/id/ENSSSCP00000049793.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624066", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624066", "resource": "KEGG Pathway" }, { "id": "R-SSC-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N728-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "Zcrb1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRRSKGVAFILFLDKDSALNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKVPEPEEVEEVEVSEEEGEDPALDSLSQAIAFQQAKIEEEQNKWRPSPGGPSTSDDSRRPRIKKSAYFSDEEELSD", "length": 216 }, "evidence": [ { "id": "A0A4X1TVT7", "url": "https://omabrowser.org/oma/group/A0A4X1TVT7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BTK3-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "ZCRB1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFALTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKESAQNCSRALNNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGEAGHLSYACPKNMLGEREPPKKKEKKKRKKVVEPEEIEEEEESEEEGEDPALDSLSQAIAVQQAKIEEEQQRWTQTAGESSVSDDSKRPRIKKSAYFSDEEELSD", "length": 216 }, "evidence": [ { "id": "A0A4X1TVT7", "url": "https://omabrowser.org/oma/group/A0A4X1TVT7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q499V6-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "Zcrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSALNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKVPEPEEEIEEVEVSEEEGEDPALDSLSQAIAFQQAKIEEEQNKWRPSTGGPSTSDDSRRPRIKKSAYFSDEEELSD", "length": 217 }, "evidence": [ { "id": "A0A4X1TVT7", "url": "https://omabrowser.org/oma/group/A0A4X1TVT7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q56JZ7-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "ZCRB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRRSKGVAFILFLDKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKIPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQAKIEEEQKKWKPSSGGPSTSDDSRRPRIKKSTYFSDEEELSD", "length": 217 }, "evidence": [ { "id": "A0A4X1TVT7", "url": "https://omabrowser.org/oma/group/A0A4X1TVT7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5SP50-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "zcrb1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGGLAPSKSTVYVSNIPFSLTNSDMHKLCSKYGKVVKVTIVKDKHTRMSKGVAFVLFLDRESAYNCSRSLNNKQLFGRMVKASIAIDNGRAAEFIRKRNYTDKSKCYECGEEGHLSYACPKNLLGEREPPPKKEKKKKKKVQQPEEVEPEDSEEEGEDPALDSLSQAIAFQQARIEEEEKRRKQAAEDASQASTSEDTHKPRIKKSAYFSDEEELSD", "length": 218 }, "evidence": [ { "id": "A0A4X1TVT7", "url": "https://omabrowser.org/oma/group/A0A4X1TVT7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8TBF4-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "ZCRB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQAKIEEEQKKWKPSSGVPSTSDDSRRPRIKKSTYFSDEEELSD", "length": 217 }, "evidence": [ { "id": "A0A4X1TVT7", "url": "https://omabrowser.org/oma/group/A0A4X1TVT7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZ96-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "Zcrb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSALNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKRKLPEPEEEIEEVEVSEEEGEDPALDSLSQAIAFQQAKIEEEQSKWRPNPGGPSTSDDSRRPRIKKSAYFSDEEELSD", "length": 217 }, "evidence": [ { "id": "A0A4X1TVT7", "url": "https://omabrowser.org/oma/group/A0A4X1TVT7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVT7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TVT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7" }, { "id": "PS50158", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC-type", "eco_id": "ECO_0000259", "start_pos": 106, "end_pos": 122, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TVT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVT7" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 88, "start_aa": "Ser", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TVY3-1", "uniprot_ac": "A0A4X1TVY3", "uniprot_id": "A0A4X1TVY3_PIG", "mass": { "chemical_mass": 40115.0, "monoisotopic_mass": 40115.0 }, "refseq": { "ac": "XP_020954678", "name": "high mobility group protein 20A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954678" }, "gene_names": [ { "name": "HMG20A", "type": "recommended", "evidence": [ { "id": "A0A4X1TVY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3" } ] }, { "name": "HMG20A", "type": "synonym", "evidence": [ { "id": "XP_020954678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954678" } ] } ], "protein_names": [ { "name": "High mobility group protein 20A", "type": "recommended", "evidence": [ { "id": "A0A4X1TVY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3/entry#names_and_taxonomy" } ] }, { "name": "HMG box-containing protein 20A", "type": "synonym", "evidence": [ { "id": "A0A4X1TVY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3/entry#names_and_taxonomy" } ] }, { "name": "HMG domain-containing protein HMGX1", "type": "synonym", "evidence": [ { "id": "A0A4X1TVY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3/entry#names_and_taxonomy" } ] }, { "name": "high mobility group protein 20A", "type": "synonym", "evidence": [ { "id": "XP_020954678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954678" } ] } ], "function": [ { "annotation": "Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVY3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3#function" }, { "database": "UniProtKB", "id": "ARBA00055661", "url": "https://www.uniprot.org/uniprotkb/ARBA00055661#function" }, { "database": "UniProtKB", "id": "F1SJ88", "url": "https://www.uniprot.org/uniprotkb/F1SJ88#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVY3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HMG20A", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3", "locus": { "chromosome": "7", "start_pos": 57570023, "end_pos": 57504465, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001871", "url": "https://www.ensembl.org/id/ENSSSCG00000001871" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001871", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001871", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22017", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22017", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156673", "url": "https://www.ncbi.nlm.nih.gov/gene/100156673", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156673", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156673", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PRRGNWT", "url": "https://omabrowser.org/oma/group/PRRGNWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TVY3", "url": "https://www.orthodb.org/?gene=A0A4X1TVY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46040", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46040", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46040:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46040:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020954678", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954678", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TVY3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TVY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJ88", "url": "https://www.uniprot.org/uniprotkb/F1SJ88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJ88-1", "url": "https://www.uniprot.org/uniprotkb/F1SJ88-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METLMTSSTLPPLFADEDGSKESNDLATTGLTHPEVPYGSGATSSTNNPEFVEDLSQGQLLQNESSNTAEGNEQRHEDEQRSKRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKQRYLDEADRDKERYMKELEQYQKTEAYKVFSRKTQDRQKGKSHRQDAARQATHDHEKEAEVKERSVFDIPIFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAVEKLEVDVIQERSRNTVLQQHLETLRQVLTSSFASMPLPGSGETPTVDTIDSYMNRLHSIILANPQDNENFIATVREVVNRLDR", "length": 347, "header": "tr|A0A4X1TVY3-1|A0A4X1TVY3_PIG Isoform 1 of High mobility group protein 20A OS=Sus scrofa OX=9823 GN=HMG20A PE=1 SV=1 CANONICAL=A0A4X1TVY3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TVY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3/entry#A0A4X1TVY3-1", "sequence": { "sequence": "METLMTSSTLPPLFADEDGSKESNDLATTGLTHPEVPYGSGATSSTNNPEFVEDLSQGQLLQNESSNTAEGNEQRHEDEQRSKRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKQRYLDEADRDKERYMKELEQYQKTEAYKVFSRKTQDRQKGKSHRQDAARQATHDHEKEAEVKERSVFDIPIFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAVEKLEVDVIQERSRNTVLQQHLETLRQVLTSSFASMPLPGSGETPTVDTIDSYMNRLHSIILANPQDNENFIATVREVVNRLDR", "length": 347, "header": "tr|A0A4X1TVY3-1|A0A4X1TVY3_PIG Isoform 1 of High mobility group protein 20A OS=Sus scrofa OX=9823 GN=HMG20A PE=1 SV=1 CANONICAL=A0A4X1TVY3-1" }, "locus": { "chromosome": "7", "start_pos": 57564367, "end_pos": 57541644, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028136.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028136.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025122.1", "url": "https://www.ensembl.org/id/ENSSSCP00000025122.1" } ] } }, { "isoform_ac": "F1SJ88-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3/entry#F1SJ88-1", "sequence": { "sequence": "METLMTSSTLPPLFADEDGSKESNDLATTGLTHPEVPYGSGATSSTNNPEFVEDLSQGQLLQNESSNTAEGNEQRHEDEQRSKRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKQRYLDEADRDKERYMKELEQYQKTEAYKVFSRKTQDRQKGKSHRQDAARQATHDHEKEAEVKERSVFDIPIFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAVEKLEVDVIQERSRNTVLQQHLETLRQVLTSSFASMPLPGSGETPTFEKL", "length": 313, "header": "tr|F1SJ88-1|F1SJ88_PIG Computationally mapped isoform of High mobility group protein 20A OS=Sus scrofa OX=9823 GN=HMG20A PE=1 SV=2 CANONICAL=A0A4X1TVY3-1" }, "locus": { "chromosome": "7", "start_pos": 57564350, "end_pos": 57541644, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002096.4", "url": "https://www.ensembl.org/id/ENSSSCT00000002096.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002046.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002046.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVY3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156673", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156673", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z937-1", "protein_name": "High mobility group protein 20A", "gene_name": "Hmg20a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESLMSSSTLPPLSADEDGSKESNGLAVTGLTHPEGPYGSAATSTTNNPEFVEDLSQGQLLQSESSNAAEGSEQRPEDEQRSKRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKQRYLDEADRDKERYMKELEQYQKTEAYKVFSRKTQDRQKGKSHRQDAARQATHDHEKETEVKERSVFDIPIFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAVEKLEVDVIQERSRNTVLQQHLETLRQMLTSSFASMPLPGSGEIPTVDTIDSYMNRLHSIILANPQDNENFIATVREVVNRLDR", "length": 347 }, "evidence": [ { "id": "A0A4X1TVY3", "url": "https://omabrowser.org/oma/group/A0A4X1TVY3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H0E1-1", "protein_name": "High mobility group protein 20A", "gene_name": "Hmg20a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESLMTSSTLPPLFADEDGSKESNDLAATGLTHPEGPYGSTATSSTNNPEFVEDLSQGQLLQSESSTAAEGNEQRHEDEQRSKRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKQRYLDEADRDKERYMKELEQYQKTEAYKVFSRKTQDRQKGKSHRQDAARQATHDHEKETEVKERSVFDIPIFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAVEKLEVDVIQERSRNTVLQQHLETLRQMLTSSFASMPLPGSGEMPTVDTIDSYMNRLHSIILANPQDNENFIATVREVVNRLDR", "length": 347 }, "evidence": [ { "id": "A0A4X1TVY3", "url": "https://omabrowser.org/oma/group/A0A4X1TVY3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9DC33-1", "protein_name": "High mobility group protein 20A", "gene_name": "Hmg20a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESLMASSTLPPLFADEDGSKESNDLATSGLTHPEGPYGSAATSTTNPEFVEDLSQGQLLQSEASNAVEGNEQRPEDEQRSKRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKQRYLDEADRDKERYMKELEQYQKTEAYKVFSRKTQDRQKGKSHRQDAARQATHDHEKETEVKERSVFDIPIFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAVEKLEVDVIQERSRNTVLQQHLETLRQMLTSSFASMPLPGSGEIPTVDTIDSYMNRLHSIILANPQDNENFIATVREVVNRLDR", "length": 346 }, "evidence": [ { "id": "A0A4X1TVY3", "url": "https://omabrowser.org/oma/group/A0A4X1TVY3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP66-1", "protein_name": "High mobility group protein 20A", "gene_name": "HMG20A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENLMTSSTLPPLFADEDGSKESNDLATTGLNHPEVPYSSGATSSTNNPEFVEDLSQGQLLQSESSNAAEGNEQRHEDEQRSKRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKQRYLDEADRDKERYMKELEQYQKTEAYKVFSRKTQDRQKGKSHRQDAARQATHDHEKETEVKERSVFDIPIFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAVEKLEVDVIQERSRNTVLQQHLETLRQVLTSSFASMPLPGSGETPTVDTIDSYMNRLHSIILANPQDNENFIATVREVVNRLDR", "length": 347 }, "evidence": [ { "id": "A0A4X1TVY3", "url": "https://omabrowser.org/oma/group/A0A4X1TVY3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVY3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVY3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVY3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVY3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TVY3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TVY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TVY3" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 103, "end_pos": 171, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 227, "end_pos": 229 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TW59-1", "uniprot_ac": "A0A4X1TW59", "uniprot_id": "A0A4X1TW59_PIG", "mass": { "chemical_mass": 35595.0, "monoisotopic_mass": 35595.0 }, "refseq": { "ac": "XP_003480819", "name": "olfactory receptor-like protein OLF4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480819" }, "gene_names": [ { "name": "LOC100739286", "type": "recommended", "evidence": [ { "id": "A0A4X1TW59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59" } ] }, { "name": "LOC100739286", "type": "synonym", "evidence": [ { "id": "XP_003480819", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480819" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TW59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor-like protein OLF4", "type": "synonym", "evidence": [ { "id": "XP_003480819", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480819" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW59", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW59", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100739286", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59", "locus": {} } ], "crossref": [ { "id": "A0A4X1TW59", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TW59", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100739286", "url": "https://www.ncbi.nlm.nih.gov/gene/100739286", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100739286", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739286", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRCSFLI", "url": "https://omabrowser.org/oma/group/WRCSFLI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TW59", "url": "https://www.orthodb.org/?gene=A0A4X1TW59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003480819", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480819", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TW59", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TW59-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPDNDTRISEFLLLGFAEEPEWQLLIFGLFLSIYLITVFGNLLIILAVSSDAQLHKPMYFFLSNLSFVDICFISTTIPKLLWNIQTQSKVITYKGCITQIYFFIFSAVLDIFLLTVMAYDRCVAICHPLHYTVIMNPQFCRLLLLVSWIMSILNSLLQSLMSLKLSFCTDVEIPHFFCDLSQIIQLACSDTILNNIVMYFASVLLGAGPLGGILYSYSKIISSIHGISSAQGKYKAFSTCASHLSVVSLFFCTSIGVYLSSAATPSSQSNATVSVIYTVVTPMLNPFIYSLRSKDIKGALKRVFMITILKRKFILGL", "length": 318, "header": "tr|A0A4X1TW59-1|A0A4X1TW59_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100739286 PE=3 SV=1 CANONICAL=A0A4X1TW59-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TW59-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59/entry#A0A4X1TW59-1", "sequence": { "sequence": "MEPDNDTRISEFLLLGFAEEPEWQLLIFGLFLSIYLITVFGNLLIILAVSSDAQLHKPMYFFLSNLSFVDICFISTTIPKLLWNIQTQSKVITYKGCITQIYFFIFSAVLDIFLLTVMAYDRCVAICHPLHYTVIMNPQFCRLLLLVSWIMSILNSLLQSLMSLKLSFCTDVEIPHFFCDLSQIIQLACSDTILNNIVMYFASVLLGAGPLGGILYSYSKIISSIHGISSAQGKYKAFSTCASHLSVVSLFFCTSIGVYLSSAATPSSQSNATVSVIYTVVTPMLNPFIYSLRSKDIKGALKRVFMITILKRKFILGL", "length": 318, "header": "tr|A0A4X1TW59-1|A0A4X1TW59_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100739286 PE=3 SV=1 CANONICAL=A0A4X1TW59-1" }, "locus": { "chromosome": "2", "start_pos": 63551097, "end_pos": 63550144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072376.1", "url": "https://www.ensembl.org/id/ENSSSCT00000072376.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072588.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072588.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 265, "start_aa": "Thr", "end_pos": 265, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr265", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW59", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100739286", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739286", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW59", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW59", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW59", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TW59", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TW59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TW59" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 265 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TWI5-1", "uniprot_ac": "A0A4X1TWI5", "uniprot_id": "A0A4X1TWI5_PIG", "mass": { "chemical_mass": 35572.0, "monoisotopic_mass": 35572.0 }, "refseq": {}, "gene_names": [ { "name": "OR2G2", "type": "recommended", "evidence": [ { "id": "A0A4X1TWI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TWI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWI5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWI5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OR2G2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5", "locus": { "chromosome": "2", "start_pos": 56631761, "end_pos": 56632714, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013945", "url": "https://www.ensembl.org/id/ENSSSCG00000013945" } ] } } ], "crossref": [ { "id": "A0A4X1TWI5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TWI5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737613", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737613", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDPMKNI", "url": "https://omabrowser.org/oma/group/WDPMKNI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TWI5", "url": "https://www.orthodb.org/?gene=A0A4X1TWI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1TWI5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TWI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGMVRSTYEGNITGFILLGFSDYPQLQKVLFVVILISYLLTILGNTTIILISHLEPKLHTPMYFFLSHLSFLDLCFTSSVIPQLLVNLWDPMKTITYGGCVVQLYVSHALGATECVLLAVMSYDRYVAICRPLQYTLLMHPHLCMALTFLAWLSGVATTLVQSTLTLQLPFCGHNQVDHFICEVPVLIKLACVDTTFNEAELFVASILFLIVPVSFILVSYGYIVQAVLKIKSATGRKKVFGTCSSHVTVVIIFYGTIMFMYLQSAKSTYKDQGKFVSLFYTVVTPMLNPLIYTLRNKEVKGALWKVLRKILVVSIT", "length": 317, "header": "tr|A0A4X1TWI5-1|A0A4X1TWI5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR2G2 PE=3 SV=1 CANONICAL=A0A4X1TWI5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TWI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5/entry#A0A4X1TWI5-1", "sequence": { "sequence": "MGMVRSTYEGNITGFILLGFSDYPQLQKVLFVVILISYLLTILGNTTIILISHLEPKLHTPMYFFLSHLSFLDLCFTSSVIPQLLVNLWDPMKTITYGGCVVQLYVSHALGATECVLLAVMSYDRYVAICRPLQYTLLMHPHLCMALTFLAWLSGVATTLVQSTLTLQLPFCGHNQVDHFICEVPVLIKLACVDTTFNEAELFVASILFLIVPVSFILVSYGYIVQAVLKIKSATGRKKVFGTCSSHVTVVIIFYGTIMFMYLQSAKSTYKDQGKFVSLFYTVVTPMLNPLIYTLRNKEVKGALWKVLRKILVVSIT", "length": 317, "header": "tr|A0A4X1TWI5-1|A0A4X1TWI5_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR2G2 PE=3 SV=1 CANONICAL=A0A4X1TWI5-1" }, "locus": { "chromosome": "2", "start_pos": 56632714, "end_pos": 56631764, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015231.4", "url": "https://www.ensembl.org/id/ENSSSCT00000015231.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014825.2", "url": "https://www.ensembl.org/id/ENSSSCP00000014825.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWI5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737613", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737613", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BED0-1", "protein_name": "Olfactory receptor", "gene_name": "OR2G28", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGMVKSTNEGNITGFILLGFSDYPQLQMALFVVILILYLLTILGNITIILISHLEPKLNTPMYFFLSHLSFLDLCFTSSVIPQLLVNLQDPMKTITYGGCVVQLYVSHALGSTECVLLAVMSYDRYVAICRPLHYALLMHPHLCMALTSLAWLSGVATTLVQSTLTLQLPLCGHHQVDHFICEVPVLIKLACVDTTFNEAELFVASILFLVVPISFILVSYGYITKAVLKINSATGRKKVFGTCSSHVTVVIMFYGTIMFMYLQSAKSTYKDQGKFVSLFYTVVTPMLNPLIYTLRNKEVKEALKKVLGKILVIKFT", "length": 317 }, "evidence": [ { "id": "A0A4X1TWI5", "url": "https://omabrowser.org/oma/group/A0A4X1TWI5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8NGZ5-1", "protein_name": "Olfactory receptor 2G2", "gene_name": "OR2G2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGMVRHTNESNLAGFILLGFSDYPQLQKVLFVLILILYLLTILGNTTIILVSRLEPKLHMPMYFFLSHLSFLYRCFTSSVIPQLLVNLWEPMKTIAYGGCLVHLYNSHALGSTECVLPAVMSCDRYVAVCRPLHYTVLMHIHLCMALASMAWLSGIATTLVQSTLTLQLPFCGHRQVDHFICEVPVLIKLACVGTTFNEAELFVASILFLIVPVSFILVSSGYIAHAVLRIKSATRRQKAFGTCFSHLTVVTIFYGTIIFMYLQPAKSRSRDQGKFVSLFYTVVTRMLNPLIYTLRIKEVKGALKKVLAKALGVNIL", "length": 317 }, "evidence": [ { "id": "A0A4X1TWI5", "url": "https://omabrowser.org/oma/group/A0A4X1TWI5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWI5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWI5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWI5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWI5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TWI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWI5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 293, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TWU8-1", "uniprot_ac": "A0A4X1TWU8", "uniprot_id": "A0A4X1TWU8_PIG", "mass": { "chemical_mass": 104770.0, "monoisotopic_mass": 104770.0 }, "refseq": { "ac": "XP_003133562", "name": "pre-mRNA-splicing factor CWC22 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133562" }, "gene_names": [ { "name": "CWC22", "type": "recommended", "evidence": [ { "id": "A0A4X1TWU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8" } ] }, { "name": "CWC22", "type": "synonym", "evidence": [ { "id": "XP_003133562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133562" } ] } ], "protein_names": [ { "name": "Pre-mRNA-splicing factor CWC22 homolog", "type": "recommended", "evidence": [ { "id": "A0A4X1TWU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8/entry#names_and_taxonomy" } ] }, { "name": "Nucampholin homolog", "type": "synonym", "evidence": [ { "id": "A0A4X1TWU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8/entry#names_and_taxonomy" } ] }, { "name": "pre-mRNA-splicing factor CWC22 homolog", "type": "synonym", "evidence": [ { "id": "XP_003133562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133562" } ] } ], "function": [ { "annotation": "Required for pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. Promotes exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWU8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8#function" }, { "database": "UniProtKB", "id": "ARBA00059429", "url": "https://www.uniprot.org/uniprotkb/ARBA00059429#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWU8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CWC22", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8", "locus": { "chromosome": "15", "start_pos": 85542258, "end_pos": 85605614, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016008", "url": "https://www.ensembl.org/id/ENSSSCG00000016008" } ] } } ], "crossref": [ { "id": "A0A4X1TWU8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TWU8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100520592", "url": "https://www.ncbi.nlm.nih.gov/gene/100520592", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520592", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520592", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ILTEDMR", "url": "https://omabrowser.org/oma/group/ILTEDMR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TWU8", "url": "https://www.orthodb.org/?gene=A0A4X1TWU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18034:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18034:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003133562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133562", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TWU8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TWU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSSVAQIKHSSSHDRRENYNSYQRTSSPEDRYPEQERSPRDRDYFDHSRSDYEHSRRGRSYDGGMESRSRDREKRRERDVDRKRSRKSPSPGRRSPEPSVTQSSSTQDEPNSKKKKEELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNIGIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKPLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQDAGSSEEEEEEEEEEGEEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFESIFKEQYDTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEPNKSSPSSSSSGSSSSSSDSESSASDSDSSDSSSESSSEESDSSSTSSQSSSSAKDVRKKGQGNPRSKEVDKLIRRQQTNDRKQEERRPEPRHQETRTERERRSEKPRDRDSRDPATKHSSDRGVPSERNSYSRAMNDRDYEMHIDVEHKHRDPKKKRGERRNSFSENEHRHRNRDSENFTRKERSNSREKSKKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRKEKSPTKQKK", "length": 903, "header": "tr|A0A4X1TWU8-1|A0A4X1TWU8_PIG Isoform 1 of Pre-mRNA-splicing factor CWC22 homolog OS=Sus scrofa OX=9823 GN=CWC22 PE=3 SV=1 CANONICAL=A0A4X1TWU8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TWU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8/entry#A0A4X1TWU8-1", "sequence": { "sequence": "MKSSVAQIKHSSSHDRRENYNSYQRTSSPEDRYPEQERSPRDRDYFDHSRSDYEHSRRGRSYDGGMESRSRDREKRRERDVDRKRSRKSPSPGRRSPEPSVTQSSSTQDEPNSKKKKEELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNIGIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKPLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQDAGSSEEEEEEEEEEGEEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFESIFKEQYDTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEPNKSSPSSSSSGSSSSSSDSESSASDSDSSDSSSESSSEESDSSSTSSQSSSSAKDVRKKGQGNPRSKEVDKLIRRQQTNDRKQEERRPEPRHQETRTERERRSEKPRDRDSRDPATKHSSDRGVPSERNSYSRAMNDRDYEMHIDVEHKHRDPKKKRGERRNSFSENEHRHRNRDSENFTRKERSNSREKSKKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRKEKSPTKQKK", "length": 903, "header": "tr|A0A4X1TWU8-1|A0A4X1TWU8_PIG Isoform 1 of Pre-mRNA-splicing factor CWC22 homolog OS=Sus scrofa OX=9823 GN=CWC22 PE=3 SV=1 CANONICAL=A0A4X1TWU8-1" }, "locus": { "chromosome": "15", "start_pos": 85588221, "end_pos": 85542258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017430.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017430.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016961.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016961.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWU8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520592", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520592", "resource": "KEGG Pathway" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MGD7-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKSSVAPMKHSSGHDRRESHNSYHRNSSPEDRYAEQERSPRDRDYSDYSRSDYERSRRGYSYDDSVESRSRDREKRRERERDVDRKRSRKSPSPGRRSPERAVTQSSTQEEPSMKKKKDEQDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQEAGSSEDEEEEEEEEEGEEEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFESIFKEQYDTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEGEQKKPPLTSSSSASSSESDSSESDSDSSESSSDSSSEGSDSSSSSSQSSASAKDTRKKKRGKARSEEVEKVVRGQQTRDRRREGGREEQRHQEGRTDRERSDRHRAQNSRNADCRDPLAKYMTDRSLPSQENSYSRVGNGRDQDMHRELEDKHGELKKKRRERRDSFSENEKQRTRNQDSESVRRKHRSKSRERSRKHSGHKSDDDRYQNGAERRWEKSTRYSEHSRESKRNQDRRREKSPTRQK", "length": 906 }, "evidence": [ { "id": "A0A4X1TWU8", "url": "https://omabrowser.org/oma/group/A0A4X1TWU8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6GJW5-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKSSMAHMKQSSGHDRRESHNSYHRRSSSPEDRYTEQDRSPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRSRKSPSPERRSPDRGVSQSSTQEEPTSKKKKDEQDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKVIKKEILDEGDSDSNTDQEAGSSEDEEEDEEEEEGEEEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFESIFKEQYDTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDAEQKKPVLTSSSSESSSGSDSSDSDSDSSESSSESSSEASDSSSSSSQSSASAKGSRKKRQGKARGEEVDKLARSHQARDRRREGGREDQRHQEGRTERARSERHRAQHSRDADWRDPPAKHMEDRSHENSYNRVGNGREQGSHREPEDRHGEPRKKRRERRDSFSENEKQRARNQDSDNVRRKDGSKSRERSRKHSGHKGDDDDRYQNGAERRWEKPSRYAEHSRESKRSQDRRREKSPTKHK", "length": 906 }, "evidence": [ { "id": "A0A4X1TWU8", "url": "https://omabrowser.org/oma/group/A0A4X1TWU8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1ACT5-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "CWC22", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKSRVTQINHGSSHERKERYSPRHRSLTPEDRDVERDRSRSPRRRRYSDDSRYDQEYSRREYYDDRSSEGRRMERGRDRYYEKWEERDYDRRRKRRLSSPDHRSPERSTVQGSNTHEEATSKKKKEEVDPILTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLVNKVNVSNIENIIYELLQENIVRGRGLLSRSILQAQGASPIFTHVYAALVAIINSKFPNIGELILKRLILNFRKGYRRNDKQLCLTSSKFVAHLMNQNVAHEVLCLEMLTLLLERPTDDSIEVAIGFLKESGLKLTEVSPRGINAIFDRLRHILHESKIDMRVQYMIEVMFAVRKDGFKDHPIIPEGLDLVEEEDQFTHMLPLEDEYNPEDVLNVFKMDPNFMENEEKYKALKKEILDEGDSESEPDQEAGSSDEEEEEDEEEDEDGQKVTVHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMDFPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFEAIFKEQYDTIHRLETNKLRNVAKMFAHLLYTDSIPWSVLECIILSEETTTSSSRIFVKIFFQELSEYMGLPNLNARLKDITLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNAPKMIMTQKQDVESSDSSSSSETDSSSDSDSDSSSSSSESSSSSDSSSSSSDSSDSDASKAKKRRTQKKNRESDKASRKKQEKKRKSLEKKTGRRRQEDRSDSESKSERNHRNLREAHRRDDTSKYHHRDESNGRDDYEAYRRDDVSKYHQRDESNGRDNYHSGRDRDHERSKDLENKHSNSKLKKAERRASFSDDESYRHGSRDNGHRSRKRERSKSGERSYNKSSPREEEEDHRYRNGSERLREKYNHYSDQYRESRKHEDRRRENSPHRRK", "length": 926 }, "evidence": [ { "id": "A0A4X1TWU8", "url": "https://omabrowser.org/oma/group/A0A4X1TWU8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A4X1TWU8", "url": "https://omabrowser.org/oma/group/A0A4X1TWU8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MWG3-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "CWC22", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKSSVAQIKHSSGHDRRENYNSYQRTSSPEDRYIEQERSPRDRGYFDSSRSDYERSRRERSYDSSMESRSRDREKRRERDVDRKRSRKSPSPGRRSPEPSVTQSSSAQDEPTAKKKKEELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNIGIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKPLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYRAIKKEILDEGDSDSNTDQDAGSSEEEEEEEEEEGEEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFESIFKEQYDTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEPDKSSSSSSSSESSSSESDSSASDSDSSDSSSESSSEESDSSSTSSQSSASAKNVRKKGHGNHRSKEVDKLIRKQEINDRKQEERRPEHRHQETRTERERRSEKPRERDSRGSGTTYTSDRGIPSARNSCSRAVHDRDQEARVDLARNHGDPEKKRERRNSFSENEHRHRNRDSENFRRRDRSKSREKNKKHSGSRSEDDRYQNGAERQWEKPSRYSEQSGESKKSQDRRREKSPTKQKK", "length": 900 }, "evidence": [ { "id": "A0A4X1TWU8", "url": "https://omabrowser.org/oma/group/A0A4X1TWU8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P53333-1", "protein_name": "Pre-mRNA-splicing factor CWC22", "gene_name": "CWC22", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTATIQDEDIKFQRENWEMIRSHVSPIISNLTMDNLQESHRDLFQVNILIGRNIICKNVVDFTLNKQNGRLIPALSALIALLNSDIPDIGETLAKELMLMFVQQFNRKDYVSCGNILQCLSILFLYDVIHEIVILQILLLLLEKNSLRLVIAVMKICGWKLALVSKKTHDMIWEKLRYILQTQELSSTLRESLETLFEIRQKDYKSGSQGLFILDPTSYTVHTHSYIVSDEDEANKELGNFEKCENFNELTMAFDTLRQKLLINNTSDTNEGSNSQLQIYDMTSTNDVEFKKKIYLVLKSSLSGDEAAHKLLKLKIANNLKKSVVDIIIKSSLQESTFSKFYSILSERMITFHRSWQTAYNETFEQNYTQDIEDYETDQLRILGKFWGHLISYEFLPMDCLKIIKLTEEESCPQGRIFIKFLFQELVNELGLDELQLRLNSSKLDGMFPLEGDAEHIRYSINFFTAIGLGLLTEDMRSRLTIIQEVEDAEEEEKKLREEEELEKLRKKARESQPTQGPKIHESRLFLQKDTRENSRSRSPFTVETRKRARSRTPPRGSRNHRNRSRTPPARRQRHR", "length": 577 }, "evidence": [ { "id": "A0A4X1TWU8", "url": "https://omabrowser.org/oma/group/A0A4X1TWU8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9HCG8-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "CWC22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPIILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDTDSNTDQDAGSSEEDEEEEEEEGEEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFEGIFKEQYDTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK", "length": 908 }, "evidence": [ { "id": "A0A4X1TWU8", "url": "https://omabrowser.org/oma/group/A0A4X1TWU8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SAG7-1", "protein_name": "MIF4G domain-containing protein / MA3 domain-containing protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRHGSSSDEEERVRRRDRRRRERSPDVRRSRTETDDVARRVRVSDDEDRKSSRRDLEIGGTVADGEGRRGDKVRRKETSDDEELARRSRKDRKEANSGSEDDRGKRIEVDSDGDGERRVNKGRNTDRVRADTSSDEEDDLKGNKKEPMEVDDDYGRRGRRRSPKVMEKQGRERSHRGSRVIADKPSDEEDDRQRSRGGRRESQRKRRDHRASDDDEEGEIRSERRGKEKNDRGSEGLLKRDRRERDLTDGHENGSRRRESERKDRSRRDDGVRDEKERRHNDKYDDSQRDKLRKEDSRKREEKKIEVPKPKLAELNPSENNAMALGKTGGVYIPPFKLARMMKEVEDKSSVEYQRLTWDALRKSINGLVNKVNASNIKNIIPELFAENLIRGRGLFCRSCMKSQMASPGFTDVFAALVAVINAKFPEVAELLLKRVVLQLKRAYKRNDKPQLLAAVKFIAHLVNQQVAEEIIALELVTILLGDPTDDSVEVAVGFVTECGAMLQDVSPRGLNGIFERFRGILHEGEIDKRVQYLIESLFATRKAKFQGHPAVRPELDLVEEKYSHDLSLDHEIDPETALDIFKPDPDFVENEKKYEALKKELLGDEESEDEDGSDASSEDNDEEEDESDEEDEEQMRIRDETETNLVNLRRTIYLTIMSSVDFEEAGHKLLKIKLEPGQEMELCIMLLECCSQERTYLRYYGLLGQRFCMINKIHQENFEKCFVQQYSMIHRLETNKLRNVAKFFAHLLGTDALPWHVLAYIRLTEEDTTSSSRIFIKILFQELSEHLGIRLLNERLQDPTMQESLESIFPKDNPKNTRFAINFFTSIGLGGITENLREYLKNMPSLIMQRQKQVAESESGSSSGSDSSDSESESESGSSSSSSSDESDREKRKRRRRS", "length": 900 }, "evidence": [ { "id": "A0A4X1TWU8", "url": "https://omabrowser.org/oma/group/A0A4X1TWU8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWU8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWU8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWU8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8" } ], "pmid": "" }, { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWU8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWU8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWU8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TWU8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 662, "end_pos": 664, "annotation": "n_glycosylation_sequon" }, { "start_pos": 839, "end_pos": 841, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TWU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TWU8" }, { "id": "PS51366", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51366" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MI", "eco_id": "ECO_0000259", "start_pos": 452, "end_pos": 568, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 662, "end_pos": 664 }, { "start_pos": 839, "end_pos": 841 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TX93-1", "uniprot_ac": "A0A4X1TX93", "uniprot_id": "A0A4X1TX93_PIG", "mass": { "chemical_mass": 34586.0, "monoisotopic_mass": 34586.0 }, "refseq": {}, "gene_names": [ { "name": "RIMKLB", "type": "recommended", "evidence": [ { "id": "A0A4X1TX93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93" } ] } ], "protein_names": [ { "name": "N-acetylaspartylglutamate synthase", "type": "recommended", "evidence": [ { "id": "A0A4X1TX93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93/entry#names_and_taxonomy" } ] }, { "name": "6.3.2.41", "type": "synonym", "evidence": [ { "id": "A0A4X1TX93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TX93", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RIMKLB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93", "locus": { "chromosome": "5", "start_pos": 62676225, "end_pos": 62715067, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000665", "url": "https://www.ensembl.org/id/ENSSSCG00000000665" } ] } } ], "crossref": [ { "id": "A0A4X1TX93", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TX93", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21621", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21621", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21621:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21621:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8964539", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964539", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "40035", "url": "https://www.rhea-db.org/rhea/40035", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TX93", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TX93-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSSVAAKLWFLTDRRIREDYPQKEILRALKAKCCEEELDFRAVVMDEVVLTIEQGNLGLRINGELITAYPQVVVVRVPTPWVQSDSDITVLRHLEKMGCRLMNRPQAILNCVNKFWTFQELAGHGVPLPDTFSYGGHENFAKMIDEAEVLEFPMVVKNTRGHRGKAVFLARDKHHLADLSHLIRHEAPYLFQKYIKESHGRDVRVIVVGGRVVGTMLRCSTDGRMQSNCSLGGVGMMCSLSEQGKQLAIQVSNILGMDVCGIDLLMKDDGSFCVCEANANPFQEPKKQKQTNKKIPREKTFLLPPS", "length": 307, "header": "tr|A0A4X1TX93-1|A0A4X1TX93_PIG Isoform 1 of N-acetylaspartylglutamate synthase OS=Sus scrofa OX=9823 GN=RIMKLB PE=3 SV=1 CANONICAL=A0A4X1TX93-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TX93-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93/entry#A0A4X1TX93-1", "sequence": { "sequence": "MCSSVAAKLWFLTDRRIREDYPQKEILRALKAKCCEEELDFRAVVMDEVVLTIEQGNLGLRINGELITAYPQVVVVRVPTPWVQSDSDITVLRHLEKMGCRLMNRPQAILNCVNKFWTFQELAGHGVPLPDTFSYGGHENFAKMIDEAEVLEFPMVVKNTRGHRGKAVFLARDKHHLADLSHLIRHEAPYLFQKYIKESHGRDVRVIVVGGRVVGTMLRCSTDGRMQSNCSLGGVGMMCSLSEQGKQLAIQVSNILGMDVCGIDLLMKDDGSFCVCEANANPFQEPKKQKQTNKKIPREKTFLLPPS", "length": 307, "header": "tr|A0A4X1TX93-1|A0A4X1TX93_PIG Isoform 1 of N-acetylaspartylglutamate synthase OS=Sus scrofa OX=9823 GN=RIMKLB PE=3 SV=1 CANONICAL=A0A4X1TX93-1" }, "locus": { "chromosome": "5", "start_pos": 62700202, "end_pos": 62682605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000721.5", "url": "https://www.ensembl.org/id/ENSSSCT00000000721.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000706.3", "url": "https://www.ensembl.org/id/ENSSSCP00000000706.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TX93", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8964539", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964539", "resource": "Reactome", "description": "Glutamate and glutamine metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TX93", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TX93", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93" } ], "pmid": "" }, { "name": "N-acetyl-L-aspartate-L-glutamate ligase activity", "id": "GO:0072590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072590", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TX93", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93" } ], "pmid": "" }, { "name": "citrate-L-glutamate ligase activity", "id": "GO:0072591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072591", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TX93", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TX93", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "40035", "name": "", "equation": "N-acetyl-L-aspartate + L-glutamate + ATP = N-acetyl-L-aspartyl-L-glutamate + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "40035", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40035" } ] }, { "id": "R-SSC-8942575", "name": "N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-5693772" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8942575", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8942575" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5693772", "participant_name": "NAASP [cytosol]", "crossref": [ { "id": "16953", "database": "ChEBI", "url": "" }, { "id": "C01042", "database": "COMPOUND", "url": "" }, { "id": "ZINC000002446417", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TX93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TX93" }, { "id": "PS50975", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50975" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ATP-grasp", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 305, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 229, "end_pos": 231 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TXH1-1", "uniprot_ac": "A0A4X1TXH1", "uniprot_id": "A0A4X1TXH1_PIG", "mass": { "chemical_mass": 8602.0, "monoisotopic_mass": 8602.0 }, "refseq": { "ac": "NP_001090942", "name": "cytochrome c oxidase subunit 6C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090942" }, "gene_names": [ { "name": "COX6C", "type": "recommended", "evidence": [ { "id": "A0A4X1TXH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1" } ] }, { "name": "COX6C", "type": "synonym", "evidence": [ { "id": "NP_001090942", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090942" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase subunit 6C", "type": "recommended", "evidence": [ { "id": "A0A4X1TXH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome c oxidase polypeptide VIc", "type": "synonym", "evidence": [ { "id": "NP_001090942", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090942" }, { "id": "A0A4X1TXH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1/entry#names_and_taxonomy" } ] }, { "name": "cytochrome c oxidase subunit 6C", "type": "synonym", "evidence": [ { "id": "NP_001090942", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090942" } ] } ], "function": [ { "annotation": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXH1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1#function" }, { "database": "UniProtKB", "id": "RU368096", "url": "https://www.uniprot.org/uniprotkb/RU368096#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXH1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "COX6C", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1", "locus": { "chromosome": "4", "start_pos": 37091849, "end_pos": 37074649, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000060790", "url": "https://www.ensembl.org/id/ENSSSCG00000060790" } ] } } ], "crossref": [ { "id": "A0A4X1TXH1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TXH1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22901", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22901", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100037989", "url": "https://www.ncbi.nlm.nih.gov/gene/100037989", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8UGH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGI", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGI&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGJ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGJ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8UGR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8UGR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZO8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZO8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZOU", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZOU&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZP8", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZP8&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSO", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSO&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ZSQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ZSQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CE2", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CE2&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR034884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051389", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051389", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100037989", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100037989", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKFAVAK", "url": "https://omabrowser.org/oma/group/CKFAVAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TXH1", "url": "https://www.orthodb.org/?gene=A0A4X1TXH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48416:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48416:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008ugh", "url": "https://www.rcsb.org/structure/pdb_00008ugh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugi", "url": "https://www.rcsb.org/structure/pdb_00008ugi", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugj", "url": "https://www.rcsb.org/structure/pdb_00008ugj", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugl", "url": "https://www.rcsb.org/structure/pdb_00008ugl", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugn", "url": "https://www.rcsb.org/structure/pdb_00008ugn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ugr", "url": "https://www.rcsb.org/structure/pdb_00008ugr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zo8", "url": "https://www.rcsb.org/structure/pdb_00008zo8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zou", "url": "https://www.rcsb.org/structure/pdb_00008zou", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zp8", "url": "https://www.rcsb.org/structure/pdb_00008zp8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsn", "url": "https://www.rcsb.org/structure/pdb_00008zsn", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zso", "url": "https://www.rcsb.org/structure/pdb_00008zso", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008zsq", "url": "https://www.rcsb.org/structure/pdb_00008zsq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009ce2", "url": "https://www.rcsb.org/structure/pdb_00009ce2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGH", "url": "https://www.rcsb.org/structure/8UGH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGI", "url": "https://www.rcsb.org/structure/8UGI", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGJ", "url": "https://www.rcsb.org/structure/8UGJ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGL", "url": "https://www.rcsb.org/structure/8UGL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGN", "url": "https://www.rcsb.org/structure/8UGN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8UGR", "url": "https://www.rcsb.org/structure/8UGR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZO8", "url": "https://www.rcsb.org/structure/8ZO8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZOU", "url": "https://www.rcsb.org/structure/8ZOU", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZP8", "url": "https://www.rcsb.org/structure/8ZP8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSN", "url": "https://www.rcsb.org/structure/8ZSN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSO", "url": "https://www.rcsb.org/structure/8ZSO", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ZSQ", "url": "https://www.rcsb.org/structure/8ZSQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CE2", "url": "https://www.rcsb.org/structure/9CE2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF02937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9707564", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9707564", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9864848", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9864848", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001090942", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090942", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TXH1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TXH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATSSLTKPQMRGLLAKRLRFHIVGAFIVSLGVATFYKFAVAEPRKKAYADFYRNYDSMKDFEEMRKAGIFQSAK", "length": 75, "header": "tr|A0A4X1TXH1-1|A0A4X1TXH1_PIG Isoform 1 of Cytochrome c oxidase subunit 6C OS=Sus scrofa OX=9823 GN=COX6C PE=1 SV=1 CANONICAL=A0A4X1TXH1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TXH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1/entry#A0A4X1TXH1-1", "sequence": { "sequence": "MATSSLTKPQMRGLLAKRLRFHIVGAFIVSLGVATFYKFAVAEPRKKAYADFYRNYDSMKDFEEMRKAGIFQSAK", "length": 75, "header": "tr|A0A4X1TXH1-1|A0A4X1TXH1_PIG Isoform 1 of Cytochrome c oxidase subunit 6C OS=Sus scrofa OX=9823 GN=COX6C PE=1 SV=1 CANONICAL=A0A4X1TXH1-1" }, "locus": { "chromosome": "4", "start_pos": 37076623, "end_pos": 37075795, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095198.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095198.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080138.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080138.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXH1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "High-resolution in situ structures of mammalian respiratory supercomplexes.", "journal": "Nature", "date": "2024", "authors": "Zheng Wan, Chai Pengxin, Zhu Jiapeng, Zhang Kai", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXH1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1" } ], "reference": [ { "type": "PubMed", "id": "38811722", "url": "https://glygen.org/publication/PubMed/38811722" } ] } ], "pathway": [ { "id": "ssc:100037989", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100037989", "resource": "KEGG Pathway" }, { "id": "R-SSC-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-SSC-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-SSC-9707564", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9707564", "resource": "Reactome", "description": "Cytoprotection by HMOX1" }, { "id": "R-SSC-9864848", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9864848", "resource": "Reactome", "description": "Complex IV assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "P11950-1", "protein_name": "Cytochrome c oxidase subunit 6C-1", "gene_name": "Cox6c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGALLPKPQMHDPLSKRLWVHIVGAFIVDLGVAAAHKFGAAKPRKKAYADFYRNHDPMKDFDEMRKAGVFRSVK", "length": 76 }, "evidence": [ { "id": "A0A4X1TXH1", "url": "https://omabrowser.org/oma/group/A0A4X1TXH1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXH1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1" } ], "pmid": "" }, { "name": "respiratory chain complex IV", "id": "GO:0045277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045277", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXH1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial electron transport, cytochrome c to oxygen", "id": "GO:0006123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006123", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXH1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TXJ7-1", "uniprot_ac": "A0A4X1TXJ7", "uniprot_id": "A0A4X1TXJ7_PIG", "mass": { "chemical_mass": 51059.0, "monoisotopic_mass": 51059.0 }, "refseq": { "ac": "XP_003134138", "name": "gamma-aminobutyric acid receptor subunit alpha-6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134138" }, "gene_names": [ { "name": "GABRA6", "type": "recommended", "evidence": [ { "id": "A0A4X1TXJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ] }, { "name": "GABRA6", "type": "synonym", "evidence": [ { "id": "XP_003134138", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134138" } ] } ], "protein_names": [ { "name": "Gamma-aminobutyric acid type A receptor subunit alpha6", "type": "synonym", "evidence": [ { "id": "A0A4X1TXJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7/entry#names_and_taxonomy" } ] }, { "name": "gamma-aminobutyric acid receptor subunit alpha-6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003134138", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134138" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GABRA6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7", "locus": { "chromosome": "16", "start_pos": 61855468, "end_pos": 61872279, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017027", "url": "https://www.ensembl.org/id/ENSSSCG00000017027" } ] } } ], "crossref": [ { "id": "A0A4X1TXJ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TXJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19052", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19052", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100516885", "url": "https://www.ncbi.nlm.nih.gov/gene/100516885", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516885", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516885", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DSRYHLK", "url": "https://omabrowser.org/oma/group/DSRYHLK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TXJ7", "url": "https://www.orthodb.org/?gene=A0A4X1TXJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18945", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18945", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02932", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02932", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-977443", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-977443", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003134138", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134138", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TXJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPLSWLYMILWVENALGKLEDEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVQTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPAEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYAIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKKKAQIAASSPVTITKATEPLEAEIVLHPDSKYHLKKRITSLTLPIVPSFEASKVLARAPILQSTPATPPPLSPVFGDTSKIDQYSRILFPVAFAGFNLVYWIVYLSKDTMEVSSSVD", "length": 453, "header": "tr|A0A4X1TXJ7-1|A0A4X1TXJ7_PIG Isoform 1 of Gamma-aminobutyric acid type A receptor subunit alpha6 OS=Sus scrofa OX=9823 GN=GABRA6 PE=3 SV=1 CANONICAL=A0A4X1TXJ7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TXJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7/entry#A0A4X1TXJ7-1", "sequence": { "sequence": "MASPLSWLYMILWVENALGKLEDEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVQTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPAEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYAIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKKKAQIAASSPVTITKATEPLEAEIVLHPDSKYHLKKRITSLTLPIVPSFEASKVLARAPILQSTPATPPPLSPVFGDTSKIDQYSRILFPVAFAGFNLVYWIVYLSKDTMEVSSSVD", "length": 453, "header": "tr|A0A4X1TXJ7-1|A0A4X1TXJ7_PIG Isoform 1 of Gamma-aminobutyric acid type A receptor subunit alpha6 OS=Sus scrofa OX=9823 GN=GABRA6 PE=3 SV=1 CANONICAL=A0A4X1TXJ7-1" }, "locus": { "chromosome": "16", "start_pos": 61872080, "end_pos": 61856472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018539.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018539.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018039.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018039.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 403, "start_aa": "Thr", "end_pos": 403, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr403", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516885", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516885", "resource": "KEGG Pathway" }, { "id": "R-SSC-977443", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-977443", "resource": "Reactome", "description": "GABA receptor activation" } ], "orthologs": [ { "uniprot_canonical_ac": "P16305-1", "protein_name": "Gamma-aminobutyric acid receptor subunit alpha-6", "gene_name": "Gabra6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLLLPWLFIILWLENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFKGPAEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRLMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKTEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQSQKAERQAQTAATPPVAKSKASESLQAEIVVHSDSKYHLKKRISSLTLPIVPSSEASKALSRTPILKSTPVSPPLLLPATGGTSKIDQYSRILFPVAFAGFNLVYWIVYLSKDTMEVSSTVE", "length": 453 }, "evidence": [ { "id": "A0A4X1TXJ7", "url": "https://omabrowser.org/oma/group/A0A4X1TXJ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P30191-1", "protein_name": "Gamma-aminobutyric acid receptor subunit alpha-6", "gene_name": "Gabra6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLLPWLFSLLWIENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFKGPAEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRLMHNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQSQKAERQAQTAAKPPVAKSKTTESLEAEIVVHSDSKYHLKKRISSLTLPIVPSSEASKVLSRTPILPSTPVTPPLLLPAIGGTSKIDQYSRILFPVAFAGFNLVYWIVYLSKDTMEVSSTVE", "length": 453 }, "evidence": [ { "id": "A0A4X1TXJ7", "url": "https://omabrowser.org/oma/group/A0A4X1TXJ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q16445-1", "protein_name": "Gamma-aminobutyric acid receptor subunit alpha-6", "gene_name": "GABRA6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKDTMEVSSSVE", "length": 453 }, "evidence": [ { "id": "A0A4X1TXJ7", "url": "https://omabrowser.org/oma/group/A0A4X1TXJ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q90845-1", "protein_name": "Gamma-aminobutyric acid receptor subunit alpha-6", "gene_name": "GABRA6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALLIAWVCVAVSIEKALGGQGDGGDLYSENITRILDKLLDGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILRLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLHSVEVPQESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQRAMRKAARAAALAAALSAATVPAEDEIVSHSDSNCNLKKRVNSVTSQADQSPEASIVSNSASQCQPVSAPPPAPPAPPPVGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKDTMEFFEPTAMHLRNDHQSN", "length": 465 }, "evidence": [ { "id": "A0A4X1TXJ7", "url": "https://omabrowser.org/oma/group/A0A4X1TXJ7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" }, { "name": "dendrite membrane", "id": "GO:0032590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032590", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" }, { "name": "GABA-A receptor complex", "id": "GO:1902711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902711", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" }, { "name": "cerebellar Golgi cell to granule cell synapse", "id": "GO:0099192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099192", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "gamma-aminobutyric acid signaling pathway", "id": "GO:0007214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007214", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" }, { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" }, { "name": "synaptic transmission, GABAergic", "id": "GO:0051932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051932", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" }, { "name": "inhibitory synapse assembly", "id": "GO:1904862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904862", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GABA-A receptor activity", "id": "GO:0004890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004890", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" }, { "name": "GABA-gated chloride ion channel activity", "id": "GO:0022851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022851", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" }, { "name": "transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1904315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TXJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" }, { "id": "PF02931", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02931" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Neurotransmitter-gated ion-channel ligand-binding", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 240, "start_aa": "Ser", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1TXJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ7" }, { "id": "PF02932", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02932" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Neurotransmitter-gated ion-channel transmembrane", "eco_id": "ECO_0000259", "start_pos": 247, "end_pos": 340, "start_aa": "Ile", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 403 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 141, "end_pos": 143 }, { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TXJ8-1", "uniprot_ac": "A0A4X1TXJ8", "uniprot_id": "A0A4X1TXJ8_PIG", "mass": { "chemical_mass": 12784.0, "monoisotopic_mass": 12784.0 }, "refseq": { "ac": "NP_001177107", "name": "large ribosomal subunit protein eL30", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177107" }, "gene_names": [ { "name": "RPL30", "type": "recommended", "evidence": [ { "id": "A0A4X1TXJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8" } ] }, { "name": "RPL30", "type": "synonym", "evidence": [ { "id": "NP_001177107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177107" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein eL30", "type": "recommended", "evidence": [ { "id": "A0A4X1TXJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L30", "type": "synonym", "evidence": [ { "id": "A0A4X1TXJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein eL30", "type": "synonym", "evidence": [ { "id": "NP_001177107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177107" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPL30", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000006081", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006081", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100156811", "url": "https://www.ncbi.nlm.nih.gov/gene/100156811", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "3J7O", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=3J7O&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "3J7P", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=3J7P&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "3J7Q", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=3J7Q&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "3J7R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=3J7R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR000231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156811", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156811", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YFQGGNN", "url": "https://omabrowser.org/oma/group/YFQGGNN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TXJ8", "url": "https://www.orthodb.org/?gene=A0A4X1TXJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11449", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11449", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00003j7o", "url": "https://www.rcsb.org/structure/pdb_00003j7o", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00003j7p", "url": "https://www.rcsb.org/structure/pdb_00003j7p", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00003j7q", "url": "https://www.rcsb.org/structure/pdb_00003j7q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00003j7r", "url": "https://www.rcsb.org/structure/pdb_00003j7r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "3J7O", "url": "https://www.rcsb.org/structure/3J7O", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "3J7P", "url": "https://www.rcsb.org/structure/3J7P", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "3J7Q", "url": "https://www.rcsb.org/structure/3J7Q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "3J7R", "url": "https://www.rcsb.org/structure/3J7R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF01248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001177107", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177107", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TXJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z554", "url": "https://www.uniprot.org/uniprotkb/F2Z554", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z554-1", "url": "https://www.uniprot.org/uniprotkb/F2Z554-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK", "length": 115, "header": "tr|A0A4X1TXJ8-1|A0A4X1TXJ8_PIG Isoform 1 of Large ribosomal subunit protein eL30 OS=Sus scrofa OX=9823 GN=RPL30 PE=1 SV=1 CANONICAL=A0A4X1TXJ8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TXJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8/entry#A0A4X1TXJ8-1", "sequence": { "sequence": "MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK", "length": 115, "header": "tr|A0A4X1TXJ8-1|A0A4X1TXJ8_PIG Isoform 1 of Large ribosomal subunit protein eL30 OS=Sus scrofa OX=9823 GN=RPL30 PE=1 SV=1 CANONICAL=A0A4X1TXJ8-1" }, "locus": { "chromosome": "4", "start_pos": 38720365, "end_pos": 38717099, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040510.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040510.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052221.1", "url": "https://www.ensembl.org/id/ENSSSCP00000052221.1" } ] } }, { "isoform_ac": "F2Z554-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8/entry#F2Z554-1", "sequence": { "sequence": "GLSFAGWRSTPAAKPIRRSYSNQQGPPFAPSLPLRFASASGRVLPAPLRRAWHCGNSFLFCSPAILAAACGWGRPAPKAGRWWPQRRRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK", "length": 147, "header": "tr|F2Z554-1|F2Z554_PIG Computationally mapped isoform of Large ribosomal subunit protein eL30 OS=Sus scrofa OX=9823 GN=RPL30 PE=1 SV=2 CANONICAL=A0A4X1TXJ8-1" }, "locus": { "chromosome": "4", "start_pos": 38720365, "end_pos": 38716756, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006672.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006672.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006493.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006493.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Structure of the mammalian ribosome-Sec61 complex to 3.4 A resolution.", "journal": "Cell", "date": "2014", "authors": "Voorhees Rebecca M, Fern\u00e1ndez Israel S, Scheres Sjors H W, Hegde Ramanujan S", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8" } ], "reference": [ { "type": "PubMed", "id": "24930395", "url": "https://glygen.org/publication/PubMed/24930395" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156811", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156811", "resource": "KEGG Pathway" }, { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "P14120-1", "protein_name": "Large ribosomal subunit protein eL30", "gene_name": "RPL30", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAPVKSQESINQKLALVIKSGKYTLGYKSTVKSLRQGKSKLIIIAANTPVLRKSELEYYAMLSKTKVYYFQGGNNELGTAVGKLFRVGVVSILEAGDSDILTTLA", "length": 105 }, "evidence": [ { "id": "A0A4X1TXJ8", "url": "https://omabrowser.org/oma/group/A0A4X1TXJ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P62888-1", "protein_name": "Large ribosomal subunit protein eL30", "gene_name": "RPL30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK", "length": 115 }, "evidence": [ { "id": "A0A4X1TXJ8", "url": "https://omabrowser.org/oma/group/A0A4X1TXJ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62889-1", "protein_name": "Large ribosomal subunit protein eL30", "gene_name": "Rpl30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK", "length": 115 }, "evidence": [ { "id": "A0A4X1TXJ8", "url": "https://omabrowser.org/oma/group/A0A4X1TXJ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P62890-1", "protein_name": "Large ribosomal subunit protein eL30", "gene_name": "Rpl30", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK", "length": 115 }, "evidence": [ { "id": "A0A4X1TXJ8", "url": "https://omabrowser.org/oma/group/A0A4X1TXJ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P67883-1", "protein_name": "Large ribosomal subunit protein eL30", "gene_name": "RPL30", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTSEK", "length": 115 }, "evidence": [ { "id": "A0A4X1TXJ8", "url": "https://omabrowser.org/oma/group/A0A4X1TXJ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q3T0D5-1", "protein_name": "Large ribosomal subunit protein eL30", "gene_name": "RPL30", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK", "length": 115 }, "evidence": [ { "id": "A0A4X1TXJ8", "url": "https://omabrowser.org/oma/group/A0A4X1TXJ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TXJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXJ8" }, { "id": "PF01248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosomal protein eL8/eL30/eS12/Gadd45", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 105, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TXR4-1", "uniprot_ac": "A0A4X1TXR4", "uniprot_id": "A0A4X1TXR4_PIG", "mass": { "chemical_mass": 24268.0, "monoisotopic_mass": 24268.0 }, "refseq": { "ac": "XP_020932363", "name": "39S ribosomal protein L22, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932363" }, "gene_names": [ { "name": "MRPL22", "type": "recommended", "evidence": [ { "id": "A0A4X1TXR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ] }, { "name": "MRPL22", "type": "synonym", "evidence": [ { "id": "XP_020932363", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932363" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL22m", "type": "recommended", "evidence": [ { "id": "A0A4X1TXR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L22, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020932363", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932363" } ] }, { "name": "39S ribosomal protein L22, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A4X1TXR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MRPL22", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4", "locus": { "chromosome": "16", "start_pos": 68228634, "end_pos": 68279417, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017065", "url": "https://www.ensembl.org/id/ENSSSCG00000017065" } ] } } ], "crossref": [ { "id": "A0A4X1TXR4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TXR4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017065", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017065", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00336", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00336", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100739015", "url": "https://www.ncbi.nlm.nih.gov/gene/100739015", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "6GAW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6GAW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6GB2", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6GB2&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6YDP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6YDP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6YDW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6YDW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NQH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NQH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NQL", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NQL&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NSH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NSH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NSI", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NSI&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7NSJ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7NSJ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8OIN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OIN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8OIQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OIQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100739015", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739015", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PAYVCHQ", "url": "https://omabrowser.org/oma/group/PAYVCHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TXR4", "url": "https://www.orthodb.org/?gene=A0A4X1TXR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13501:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13501:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00006gaw", "url": "https://www.rcsb.org/structure/pdb_00006gaw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006gb2", "url": "https://www.rcsb.org/structure/pdb_00006gb2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006ydp", "url": "https://www.rcsb.org/structure/pdb_00006ydp", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006ydw", "url": "https://www.rcsb.org/structure/pdb_00006ydw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nqh", "url": "https://www.rcsb.org/structure/pdb_00007nqh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nql", "url": "https://www.rcsb.org/structure/pdb_00007nql", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nsh", "url": "https://www.rcsb.org/structure/pdb_00007nsh", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nsi", "url": "https://www.rcsb.org/structure/pdb_00007nsi", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007nsj", "url": "https://www.rcsb.org/structure/pdb_00007nsj", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008oin", "url": "https://www.rcsb.org/structure/pdb_00008oin", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008oiq", "url": "https://www.rcsb.org/structure/pdb_00008oiq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6GAW", "url": "https://www.rcsb.org/structure/6GAW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6GB2", "url": "https://www.rcsb.org/structure/6GB2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6YDP", "url": "https://www.rcsb.org/structure/6YDP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6YDW", "url": "https://www.rcsb.org/structure/6YDW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NQH", "url": "https://www.rcsb.org/structure/7NQH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NQL", "url": "https://www.rcsb.org/structure/7NQL", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NSH", "url": "https://www.rcsb.org/structure/7NSH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NSI", "url": "https://www.rcsb.org/structure/7NSI", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7NSJ", "url": "https://www.rcsb.org/structure/7NSJ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OIN", "url": "https://www.rcsb.org/structure/8OIN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OIQ", "url": "https://www.rcsb.org/structure/8OIQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020932363", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932363", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TXR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLT3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R263", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R263", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R263-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R263-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3D6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3D6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1XUH2", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XUH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1XUH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XUH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAVLERLGGLWMQNLRGKLALRLLSSHSILPQSHIHTSASVEISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFSDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLYVAESTSGRGQYLKRIRYHGRGRFGIMEKVFCHYFVKLVEGPPPPREAPKTAVAHAREYIQELRNRTITHAL", "length": 210, "header": "tr|A0A4X1TXR4-1|A0A4X1TXR4_PIG Isoform 1 of Large ribosomal subunit protein uL22m OS=Sus scrofa OX=9823 GN=MRPL22 PE=1 SV=1 CANONICAL=A0A4X1TXR4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TXR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4/entry#A0A4X1TXR4-1", "sequence": { "sequence": "MAAAVLERLGGLWMQNLRGKLALRLLSSHSILPQSHIHTSASVEISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFSDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLYVAESTSGRGQYLKRIRYHGRGRFGIMEKVFCHYFVKLVEGPPPPREAPKTAVAHAREYIQELRNRTITHAL", "length": 210, "header": "tr|A0A4X1TXR4-1|A0A4X1TXR4_PIG Isoform 1 of Large ribosomal subunit protein uL22m OS=Sus scrofa OX=9823 GN=MRPL22 PE=1 SV=1 CANONICAL=A0A4X1TXR4-1" }, "locus": { "chromosome": "16", "start_pos": 68277589, "end_pos": 68234571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018580.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018580.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018080.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018080.3" } ] } }, { "isoform_ac": "A0A5G2QLT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4/entry#A0A5G2QLT3-1", "sequence": { "sequence": "LGAPPLRARRYGARGGPGRTAGSATGVAGLGRAGSRARRSAAEPRLRLERLGRLEPSPGVRHFSLLTAIKRLLSSHSILPQSHIHTSASVEISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFSDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLYVAESTSGRGQYLKRIRYHGRGRFGIMEKVFCHYFVKLVEGPPPPREAPKTAVAHAREYIQELRNRTITHAL", "length": 257, "header": "tr|A0A5G2QLT3-1|A0A5G2QLT3_PIG Computationally mapped isoform of Large ribosomal subunit protein uL22m OS=Sus scrofa OX=9823 GN=MRPL22 PE=1 SV=1 CANONICAL=A0A4X1TXR4-1" }, "locus": { "chromosome": "16", "start_pos": 68279218, "end_pos": 68234571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082547.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082547.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065532.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065532.1" } ] } }, { "isoform_ac": "A0A5G2R263-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4/entry#A0A5G2R263-1", "sequence": { "sequence": "MAAAVLERLGKDRLGLKRWKKGVTWESKLTAFVDFAGGLWMQNLRGKLALRLLSSHSILPQSHIHTSASVEISRKWEKKNKIVYPPQLPGEPRRPAIRGMSIDQALAQLEFSDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLYVAESTSGRGQYLKRIRYHGRGRFGIMEKVFCHYFVKLVEGPPPPREAPKTAVAHAREYIQELRNRTITHAL", "length": 215, "header": "tr|A0A5G2R263-1|A0A4X1TXR4_PIG Computationally mapped isoform of Large ribosomal subunit protein uL22m OS=Sus scrofa OX=9823 GN=MRPL22 PE=1 SV=1 CANONICAL=A0A4X1TXR4-1" }, "locus": { "chromosome": "16", "start_pos": 68277589, "end_pos": 68234571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084986.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084986.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068287.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068287.1" } ] } }, { "isoform_ac": "A0A5G2R3D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4/entry#A0A5G2R3D6-1", "sequence": { "sequence": "MWVPSLALLILKKSECLLFCRLLSSHSILPQSHIHTSASVEISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFSDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLYVAESTSGRGQYLKRIRYHGRGRFGIMEKVFCHYFVKLVEGPPPPREAPKTAVAHAREYIQELRNRTITHAL", "length": 207, "header": "tr|A0A5G2R3D6-1|A0A4X1TXR4_PIG Computationally mapped isoform of Large ribosomal subunit protein uL22m OS=Sus scrofa OX=9823 GN=MRPL22 PE=1 SV=1 CANONICAL=A0A4X1TXR4-1" }, "locus": { "chromosome": "16", "start_pos": 68251595, "end_pos": 68234571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080775.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080775.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070857.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070857.1" } ] } }, { "isoform_ac": "A0A8D1XUH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4/entry#A0A8D1XUH2-1", "sequence": { "sequence": "MAAAVLERLGKDRLGLKRWKKGVTWESKLTAFVDFAGGLWMQNLRGKLALRLLSSHSILPQSHIHTSASVEISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFSDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLYVAESTSGRGQYLKRIRYHGRGRFGIMEKVFCHYFVKLVEGPPPPREAPKTAVAHAREYIQELRNRTITHAL", "length": 237, "header": "tr|A0A8D1XUH2-1|A0A4X1TXR4_PIG Computationally mapped isoform of Large ribosomal subunit protein uL22m OS=Sus scrofa OX=9823 GN=MRPL22 PE=1 SV=1 CANONICAL=A0A4X1TXR4-1" }, "locus": { "chromosome": "16", "start_pos": 68277589, "end_pos": 68234571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037258.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037258.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042500.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042500.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.", "journal": "Nature", "date": "2018", "authors": "Kummer Eva, Leibundgut Marc, Rackham Oliver, Lee Richard G, Boehringer Daniel, Filipovska Aleksandra, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ], "reference": [ { "type": "PubMed", "id": "30089917", "url": "https://glygen.org/publication/PubMed/30089917" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Structural insights into mammalian mitochondrial translation elongation catalyzed by mtEFG1.", "journal": "EMBO J.", "date": "2020", "authors": "Kummer E, Ban N", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ], "reference": [ { "type": "PubMed", "id": "32602580", "url": "https://glygen.org/publication/PubMed/32602580" } ] }, { "title": "Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.", "journal": "Mol. Cell", "date": "2021", "authors": "Kummer Eva, Schubert Katharina Noel, Schoenhut Tanja, Scaiola Alain, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ], "reference": [ { "type": "PubMed", "id": "33878294", "url": "https://glygen.org/publication/PubMed/33878294" } ] }, { "title": "Molecular basis of translation termination at noncanonical stop codons in human mitochondria.", "journal": "Science", "date": "2023", "authors": "Saurer Martin, Leibundgut Marc, Nadimpalli Hima Priyanka, Scaiola Alain, Sch\u00f6nhut Tanja, Lee Richard G, Siira Stefan J, Rackham Oliver, Dreos Ren\u00e9, Lenar\u010di\u010d Tea, Kummer Eva, Gatfield David, Filipovska Aleksandra, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ], "reference": [ { "type": "PubMed", "id": "37141370", "url": "https://glygen.org/publication/PubMed/37141370" } ] } ], "pathway": [ { "id": "ssc:100739015", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739015", "resource": "KEGG Pathway" }, { "id": "R-SSC-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-SSC-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-SSC-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ], "pmid": "" }, { "name": "large ribosomal subunit", "id": "GO:0015934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015934", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A4X1TXR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4#function" }, { "id": "A0A4X1TXR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXR4" }, { "id": "6YDW", "database": "PDB", "url": "https://www.rcsb.org/structure/6YDW" } ], "binding_site_uniprot": 166, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0007829", "start_pos": 166, "end_pos": 166, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TXT8-1", "uniprot_ac": "A0A4X1TXT8", "uniprot_id": "A0A4X1TXT8_PIG", "mass": { "chemical_mass": 34504.0, "monoisotopic_mass": 34504.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TXT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXT8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXT8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXT8#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXT8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXT8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXT8", "locus": {} } ], "crossref": [ { "id": "A0A4X1TXT8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TXT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KSNQHEG", "url": "https://omabrowser.org/oma/group/KSNQHEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1TXT8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TXT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIEFVLLGFADIPQFHWFLFGVFLVIYLIILLGNGIIILITKVDATLQTPMYFFLSIFSFLEICYVSVTLPRMLMDIWTQKGKISVFTCATQMCFFLMLAGTECFLLAVMAYDRYVAICNPLHYPLVMNPKVCVQLVVASWISGAPVQIGNTYQIFSLPFCGSNQINHFFCDIPPLLKLACGDIFYNEMMVYILAVLFLTLPFMLILGFYTRIISNILKLPSKTGQTKAFSTCSSHIIVVLLFYGSAAVTYLKPKSNQYEGIDKLLSLFYTILTPMFNPMVYSLRNKDVRKAIRKFLHKLSAL", "length": 303, "header": "tr|A0A4X1TXT8-1|A0A4X1TXT8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1TXT8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TXT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXT8/entry#A0A4X1TXT8-1", "sequence": { "sequence": "MIEFVLLGFADIPQFHWFLFGVFLVIYLIILLGNGIIILITKVDATLQTPMYFFLSIFSFLEICYVSVTLPRMLMDIWTQKGKISVFTCATQMCFFLMLAGTECFLLAVMAYDRYVAICNPLHYPLVMNPKVCVQLVVASWISGAPVQIGNTYQIFSLPFCGSNQINHFFCDIPPLLKLACGDIFYNEMMVYILAVLFLTLPFMLILGFYTRIISNILKLPSKTGQTKAFSTCSSHIIVVLLFYGSAAVTYLKPKSNQYEGIDKLLSLFYTILTPMFNPMVYSLRNKDVRKAIRKFLHKLSAL", "length": 303, "header": "tr|A0A4X1TXT8-1|A0A4X1TXT8_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1TXT8-1" }, "locus": { "chromosome": "8", "start_pos": 54288183, "end_pos": 54287275, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043803.1", "url": "https://www.ensembl.org/id/ENSSSCT00000043803.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055181.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055181.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXT8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXT8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LGC0-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100765827", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQFKHVKLQRANELKIIETNFTLPVEFVLLGFSDIPKLHWFLFGIFLFIYIIILLGNGIIILITRVEPSLQTPMYFFISNFSFLEICYVSVTLPRMLMDLSTLKGSISFFACATQMCLFLILGATECFLLAVMAYDRYVAICNPLHYPIVMSHKVCTELVIGSWVIGIPIQVGQTYQILSLPFCESNQINHFFCDIPPLLKLACGNIFVNEIVVFIFAVLIVTVPFMLILASYSRIISTILKLPSNTGRTKAFSTCSSHLIVVFLFYGSASITYLKPKSNNYEGTDKLLSLFYTILTPMFNPLIYSLRNKDVTGALRKLFTRLVAM", "length": 326 }, "evidence": [ { "id": "A0A4X1TXT8", "url": "https://omabrowser.org/oma/group/A0A4X1TXT8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BGV9-1", "protein_name": "Olfactory receptor", "gene_name": "OR10AG75", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSRNVNLEREDHLKITETNLTIMMEFVLLGFTDIPQFQWFLFGIFLVIYMIILLGNGVIILITRVDAILQTPMYFFLRNFSFLEICYVSITLPRMLMDLWTQKGTISLFTCATQMCFFLILGTTECFLLAVMAYDRCVAICDPLHYPLVMCPEVRIRLVVASWISAVPVQIGQTCQIFSLPFCGSNTINHFFCDIPPLLKLACGDIFVNEMVVYIFGILFVTVPFLLILGFYIRIISTILKLPANTGWTKAFSTCSSHITVVLLFYGSATVTYLKPKSNQHEGIDKMISLFYTILTPMVNPIIYSLRNKDVRKAMRKFLP", "length": 321 }, "evidence": [ { "id": "A0A4X1TXT8", "url": "https://omabrowser.org/oma/group/A0A4X1TXT8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7TR54-1", "protein_name": "Olfactory receptor", "gene_name": "Or10ag52", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQSKYVNLQRANKFKITDTNLTVPIEFVLLGFSDIPQLHWFLFGIFLFIYMIILLGNGIIILITKVEPTLQTPMYFFISNFSFLEICYVSVTLPRMLMDLFTLKGNISFLACATQMCLFLILGATECFLLAVMSYDRYVAICNPLLYPVVMSSKVCTQLVVGSWVIGVPIQVGQTYQILSLPFCESNQINHFFCDIPPLLKLACGNIFVNELVVFIFAVLIVTIPFMLILASYSRIISTILKLPSNTGRTKAFSTCSSHLIVVFLFYGSASITYLKPKSNKFEGTDKLLSLFYTILTPMFNPLIYSLRNKDVTGALKKLFTRLLAL", "length": 326 }, "evidence": [ { "id": "A0A4X1TXT8", "url": "https://omabrowser.org/oma/group/A0A4X1TXT8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXT8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXT8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXT8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXT8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXT8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXT8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TXT8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TXT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "uniprot_ac": "A0A4X1TY10", "uniprot_id": "A0A4X1TY10_PIG", "mass": { "chemical_mass": 35637.0, "monoisotopic_mass": 35637.0 }, "refseq": { "ac": "XP_003354203", "name": "olfactory receptor 2L2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354203" }, "gene_names": [ { "name": "LOC100627324", "type": "recommended", "evidence": [ { "id": "A0A4X1TY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10" } ] }, { "name": "LOC100627324", "type": "synonym", "evidence": [ { "id": "XP_003354203", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354203" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2L2-like", "type": "synonym", "evidence": [ { "id": "XP_003354203", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354203" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100627324", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10", "locus": {} } ], "crossref": [ { "id": "A0A4X1TY10", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TY10", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100627324", "url": "https://www.ncbi.nlm.nih.gov/gene/100627324", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100627324", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627324", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TY10", "url": "https://www.orthodb.org/?gene=A0A4X1TY10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003354203", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354203", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TY10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TY10-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312, "header": "tr|A0A4X1TY10-1|A0A4X1TY10_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100627324 PE=3 SV=1 CANONICAL=A0A4X1TY10-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TY10-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10/entry#A0A4X1TY10-1", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312, "header": "tr|A0A4X1TY10-1|A0A4X1TY10_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100627324 PE=3 SV=1 CANONICAL=A0A4X1TY10-1" }, "locus": { "chromosome": "2", "start_pos": 55381697, "end_pos": 55380762, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075484.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075484.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061962.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061962.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100627324", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627324", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "A0A4X1TY10", "url": "https://omabrowser.org/oma/group/A0A4X1TY10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY10" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 228, "end_pos": 230 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TY32-1", "uniprot_ac": "A0A4X1TY32", "uniprot_id": "A0A4X1TY32_PIG", "mass": { "chemical_mass": 60261.0, "monoisotopic_mass": 60261.0 }, "refseq": {}, "gene_names": [ { "name": "SLC22A13", "type": "recommended", "evidence": [ { "id": "A0A4X1TY32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" } ] } ], "protein_names": [ { "name": "Solute carrier family 22 member 13", "type": "synonym", "evidence": [ { "id": "A0A4X1TY32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC22A13", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32", "locus": { "chromosome": "13", "start_pos": 23130829, "end_pos": 23120222, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011256", "url": "https://www.ensembl.org/id/ENSSSCG00000011256" } ] } } ], "crossref": [ { "id": "A0A4X1TY32", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TY32", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011256", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011256", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17374", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-196807", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-196807", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TY32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TY32-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJT6", "url": "https://www.uniprot.org/uniprotkb/F1SJT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SJT6-1", "url": "https://www.uniprot.org/uniprotkb/F1SJT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHFSEVLAEIGTFGRFQVQLLILLSVPNFLTAFYMFAQVFMVLDETHHCSVAWVKNQTLNLSTAEQLALSVPLDAAGSPEPCLMFQPPPDGASLEDILSHRFNKTQPCKTGWVYPEGRPRSLMNEFNLVCDRKHLKETSQSVYMAGLLVGALIFGPLCDWIGRKITVLLQLLLFGILGLSTAFVPSFELYMALRFAVATAVAGYTFSNITLLTEWVGPSWRTRTVVVAQCSFSVGQMALAGLAYGIRNWRLLQIAGASPVFLLFFYIWALPESARWLLTHGRVEEAKQLIQKAASVNRKKLSPELLSQLVPEKTGPTGNALDLFRHPQLRKVTLILSYVWFVDSLVYYGLGFKVGDFGLDIYLTQLIFGAVEVPARYSSIFMMERLGRKWSQMGTLLLGGLMCIAIIFVPADLPVVITVLALVGKFATAAGFTVSYVYSAELYPTVIRQTGLGLVGIPSRIGGILTPFVIMLDEYHAAAPMLIYGILPIGAGLLCALLPETRGQSLKDTIHDLEQKSYPRSQKDSEGDLEASGSTSSSGVAFSNPYL", "length": 548, "header": "tr|A0A4X1TY32-1|A0A4X1TY32_PIG Isoform 1 of Solute carrier family 22 member 13 OS=Sus scrofa OX=9823 GN=SLC22A13 PE=1 SV=1 CANONICAL=A0A4X1TY32-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TY32-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32/entry#A0A4X1TY32-1", "sequence": { "sequence": "MAHFSEVLAEIGTFGRFQVQLLILLSVPNFLTAFYMFAQVFMVLDETHHCSVAWVKNQTLNLSTAEQLALSVPLDAAGSPEPCLMFQPPPDGASLEDILSHRFNKTQPCKTGWVYPEGRPRSLMNEFNLVCDRKHLKETSQSVYMAGLLVGALIFGPLCDWIGRKITVLLQLLLFGILGLSTAFVPSFELYMALRFAVATAVAGYTFSNITLLTEWVGPSWRTRTVVVAQCSFSVGQMALAGLAYGIRNWRLLQIAGASPVFLLFFYIWALPESARWLLTHGRVEEAKQLIQKAASVNRKKLSPELLSQLVPEKTGPTGNALDLFRHPQLRKVTLILSYVWFVDSLVYYGLGFKVGDFGLDIYLTQLIFGAVEVPARYSSIFMMERLGRKWSQMGTLLLGGLMCIAIIFVPADLPVVITVLALVGKFATAAGFTVSYVYSAELYPTVIRQTGLGLVGIPSRIGGILTPFVIMLDEYHAAAPMLIYGILPIGAGLLCALLPETRGQSLKDTIHDLEQKSYPRSQKDSEGDLEASGSTSSSGVAFSNPYL", "length": 548, "header": "tr|A0A4X1TY32-1|A0A4X1TY32_PIG Isoform 1 of Solute carrier family 22 member 13 OS=Sus scrofa OX=9823 GN=SLC22A13 PE=1 SV=1 CANONICAL=A0A4X1TY32-1" }, "locus": { "chromosome": "13", "start_pos": 23127581, "end_pos": 23120289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077673.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077673.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073041.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073041.1" } ] } }, { "isoform_ac": "F1SJT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32/entry#F1SJT6-1", "sequence": { "sequence": "MAHFSEVLAEIGTFGRFQVQLLILLSVPNFLTAFYMFAQVFMVLDETHHCSVAWVKNQTLNLSTAEQLALSVPLDAAGSPEPCLMFQPPPDGASLEDILSHRFNKTQPCKTGWVYPEGRPRSLMNEFNLVCDRKHLKETSQSVYMAGLLVGALIFGPLCDWIGRKITVLLQLLLFGILGLSTAFVPSFELYMALRFAVATAVAGYTFSNITLLTEWVGPSWRTRTVVVAQCSFSVGQMALAGLAYGIRNWRLLQIAGASPVFLLFFYIWALPESARWLLTHGRVEEAKQLIQKAASVNRKKLSPELLSQVLAAAGPSCLPLTLFVDSLVYYGLGFKVGDFGLDIYLTQLIFGAVEVPARYSSIFMMERLGRKWSQMGTLLLGGLMCIAIIFVPADLPVVITVLALVGKFATAAGFTVSYVYSAELYPTVIRQTGLGLVGIPSRIGGILTPFVIMLDEYHAAAPMLIYGILPIGAGLLCALLPETRGQSLKDTIHDLEQKSYPR", "length": 503, "header": "tr|F1SJT6-1|A0A4X1TY32_PIG Computationally mapped isoform of Solute carrier family 22 member 13 OS=Sus scrofa OX=9823 GN=SLC22A13 PE=1 SV=4 CANONICAL=A0A4X1TY32-1" }, "locus": { "chromosome": "13", "start_pos": 23127320, "end_pos": 23120289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012323.4", "url": "https://www.ensembl.org/id/ENSSSCT00000012323.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012001.4", "url": "https://www.ensembl.org/id/ENSSSCP00000012001.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SJT6", "url": "https://www.uniprot.org/uniprotkb/F1SJT6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-196807", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-196807", "resource": "Reactome", "description": "Nicotinate metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of fatty acid metabolic process", "id": "GO:0045922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045922", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" } ], "pmid": "" }, { "name": "positive regulation of T cell mediated cytotoxicity directed against tumor cell target", "id": "GO:0002854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002854", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "urate transmembrane transporter activity", "id": "GO:0015143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015143", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" } ], "pmid": "" }, { "name": "nicotinate transmembrane transporter activity", "id": "GO:0090416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090416", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY32", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TY32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY32" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 503, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 209, "end_pos": 211 }, { "start_pos": 57, "end_pos": 59 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TY84-1", "uniprot_ac": "A0A4X1TY84", "uniprot_id": "A0A4X1TY84_PIG", "mass": { "chemical_mass": 14127.0, "monoisotopic_mass": 14127.0 }, "refseq": {}, "gene_names": [ { "name": "SLPI", "type": "recommended", "evidence": [ { "id": "A0A4X1TY84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84" } ] } ], "protein_names": [ { "name": "Secretory leukocyte peptidase inhibitor", "type": "synonym", "evidence": [ { "id": "A0A4X1TY84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLPI", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84", "locus": { "chromosome": "17", "start_pos": 47595803, "end_pos": 47598387, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000039573", "url": "https://www.ensembl.org/id/ENSSSCG00000039573" } ] } } ], "crossref": [ { "id": "cd00199", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00199", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR008197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050514", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050514", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NLKCCKG", "url": "https://omabrowser.org/oma/group/NLKCCKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19441", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19441", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19441:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19441:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00095", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00095", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1TY84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TY84-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSSGLLPFVLLALGILAPWAVEGAENALKGGACPPRKIVQCLRYEKPKCTSDWQCPDKKKCCRDTCGIKCLNPVAITNPVKVKPGKCPVVYGQCMMLNPPNHCKTDSQCLGDLKCCKSMCGKVCLTPVKA", "length": 131, "header": "tr|A0A4X1TY84-1|A0A4X1TY84_PIG Isoform 1 of Secretory leukocyte peptidase inhibitor OS=Sus scrofa OX=9823 GN=SLPI PE=4 SV=1 CANONICAL=A0A4X1TY84-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TY84-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84/entry#A0A4X1TY84-1", "sequence": { "sequence": "MKSSGLLPFVLLALGILAPWAVEGAENALKGGACPPRKIVQCLRYEKPKCTSDWQCPDKKKCCRDTCGIKCLNPVAITNPVKVKPGKCPVVYGQCMMLNPPNHCKTDSQCLGDLKCCKSMCGKVCLTPVKA", "length": 131, "header": "tr|A0A4X1TY84-1|A0A4X1TY84_PIG Isoform 1 of Secretory leukocyte peptidase inhibitor OS=Sus scrofa OX=9823 GN=SLPI PE=4 SV=1 CANONICAL=A0A4X1TY84-1" }, "locus": { "chromosome": "17", "start_pos": 47598372, "end_pos": 47596016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074297.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074297.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064681.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064681.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G7R6-1", "protein_name": "Antileukoproteinase", "gene_name": "Slpi", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLGTAHQSHSAFTMKSSTFFPFMVLLALGILASWTVEGGKNDAIKSGACPSRRPVNCLRKEKPECDSDWQCPGNKRCCQFRCGFKCIDPLPIRTAVRSKPGKCPKIQGQCLMLNPPNRCKRDGECAGNYKCCLGMCGKLCLLPQ", "length": 144 }, "evidence": [ { "id": "A0A4X1TY84", "url": "https://omabrowser.org/oma/group/A0A4X1TY84/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1LM48-1", "protein_name": "Secretory leukocyte peptidase inhibitor, pseudogene 2", "gene_name": "Slpi-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNFSGLFPHLVLLALGILAPWGVEGEKSGAIKAGACPARKPVQCLKREKPECSTDWGCPGKQRCCQDTCGFKCLNPVPIPRPVKKKSGSCLRFAVPCRPLPPLSQCQNDGQCDGKYKCCQRICGKFCFPPK", "length": 131 }, "evidence": [ { "id": "A0A4X1TY84", "url": "https://omabrowser.org/oma/group/A0A4X1TY84/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P03973-1", "protein_name": "Antileukoproteinase", "gene_name": "SLPI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGKKRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCMGMCGKSCVSPVKA", "length": 132 }, "evidence": [ { "id": "A0A4X1TY84", "url": "https://omabrowser.org/oma/group/A0A4X1TY84/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97430-1", "protein_name": "Antileukoproteinase", "gene_name": "Slpi", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSCGLLPFTVLLALGILAPWTVEGGKNDAIKIGACPAKKPAQCLKLEKPQCRTDWECPGKQRCCQDACGSKCVNPVPIRKPVWRKPGRCVKTQARCMMLNPPNVCQRDGQCDGKYKCCEGICGKVCLPPM", "length": 131 }, "evidence": [ { "id": "A0A4X1TY84", "url": "https://omabrowser.org/oma/group/A0A4X1TY84/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84" } ], "pmid": "" }, { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "antibacterial humoral response", "id": "GO:0019731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019731", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84" } ], "pmid": "" }, { "name": "negative regulation of viral genome replication", "id": "GO:0045071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045071", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84" } ], "pmid": "" }, { "name": "host-mediated perturbation of symbiont process", "id": "GO:0051851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051851", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TY84", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TY84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TY84" }, { "id": "PS51390", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51390" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WAP", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 75, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TYG4-1", "uniprot_ac": "A0A4X1TYG4", "uniprot_id": "A0A4X1TYG4_PIG", "mass": { "chemical_mass": 44311.0, "monoisotopic_mass": 44311.0 }, "refseq": { "ac": "XP_005666733", "name": "neuropeptide Y receptor type 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666733" }, "gene_names": [ { "name": "NPY1R", "type": "recommended", "evidence": [ { "id": "A0A4X1TYG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4" } ] }, { "name": "NPY1R", "type": "synonym", "evidence": [ { "id": "XP_005666733", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666733" } ] } ], "protein_names": [ { "name": "Neuropeptide Y receptor type 1", "type": "recommended", "evidence": [ { "id": "A0A4X1TYG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4/entry#names_and_taxonomy" } ] }, { "name": "neuropeptide Y receptor type 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005666733", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666733" } ] } ], "function": [ { "annotation": "Receptor for neuropeptide Y and peptide YY.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4#function" }, { "database": "UniProtKB", "id": "ARBA00053878", "url": "https://www.uniprot.org/uniprotkb/ARBA00053878#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NPY1R", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4", "locus": { "chromosome": "8", "start_pos": 52152646, "end_pos": 52162328, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008888", "url": "https://www.ensembl.org/id/ENSSSCG00000008888" } ] } } ], "crossref": [ { "id": "A0A4X1TYG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TYG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15395", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15395", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "397547", "url": "https://www.ncbi.nlm.nih.gov/gene/397547", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QFFFHFC", "url": "https://omabrowser.org/oma/group/QFFFHFC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TYG4", "url": "https://www.orthodb.org/?gene=A0A4X1TYG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24235:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24235:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005666733", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666733", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TYG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSTLSSQVENHSIYYNFSEKNSQFLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEVMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPSNRHAYVGIAVIWVLAVASSLPFLIYQVLTDEPFQNVTLDAFKDKYVCFDKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINVMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCINPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYEVIAMSTMHTDVSKTSLKQASPVALKKIHSDDNEKI", "length": 383, "header": "tr|A0A4X1TYG4-1|A0A4X1TYG4_PIG Isoform 1 of Neuropeptide Y receptor type 1 OS=Sus scrofa OX=9823 GN=NPY1R PE=3 SV=1 CANONICAL=A0A4X1TYG4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TYG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4/entry#A0A4X1TYG4-1", "sequence": { "sequence": "MNSTLSSQVENHSIYYNFSEKNSQFLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEVMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPSNRHAYVGIAVIWVLAVASSLPFLIYQVLTDEPFQNVTLDAFKDKYVCFDKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINVMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCINPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYEVIAMSTMHTDVSKTSLKQASPVALKKIHSDDNEKI", "length": 383, "header": "tr|A0A4X1TYG4-1|A0A4X1TYG4_PIG Isoform 1 of Neuropeptide Y receptor type 1 OS=Sus scrofa OX=9823 GN=NPY1R PE=3 SV=1 CANONICAL=A0A4X1TYG4-1" }, "locus": { "chromosome": "8", "start_pos": 52155464, "end_pos": 52154208, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009731.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009731.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009480.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009480.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XZA0-1", "protein_name": "Neuropeptide Y receptor type 1", "gene_name": "NPY1R", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNASVLDPLGNNSSHLNFSEKNSQILQFEDEDCHVPLAMVFTLALAYGTVIILGVSGNLALIVIILKQKEMRNVTNILIVNLSFSDLLVTIMCLPFTFVYTLMDHWIFGEAMCKLNPFVQCASITVSVFSLVLIAIERHQLIINPRGWRPNNRHAYMGIAAIWVLATASSLPFLIYHVLTDEPFRNITFDEYKDKYVCLDLFPLDTARLSYTTTLLVIQYFGPLCFIFICYLKIYFRLKKRSNMMDKMRDSKYRSSETKRINIMLISIVVAFAVCWLPLTIFNIVFDWNHEILPVATCSHNLLFLICHLTAMISTCVNPIFYGFLNKNLQRDLQFLFHFCHFRSREEDYETIAMSTMHTDVSKTSLKQASPVAFKKINSDDDDKI", "length": 385 }, "evidence": [ { "id": "A0A4X1TYG4", "url": "https://omabrowser.org/oma/group/A0A4X1TYG4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A7UD89-1", "protein_name": "Neuropeptide Y receptor type 1", "gene_name": "npy1r", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPDSAFSPPVPPIAALNCSLDLSNCSITNLSAIAYGDECYGSHSLFVIMAVAYSAVVLLGVIGNLALILVIARQRELHNVTNVLIANLSVSDLLMAVVCLPFTFIYTFMDHWVFGAVMCKLNSLVQCCSVSVSIFSLVLIAIERHQLILHPRGWRPSLNHACLGISLTWALAVLTATPFLLFSRVTDAPLKQLPSVFQEQYRGKVVCVEEWPSREIKLTYTTGMLVLQYITPLTFIFICYLKIYTRLQRRNNMMERIRENKYRSSESKRINIMLFSIVVAFAVCWLPLNVFNAVIDWNHEVAMNCTHNLLFSLCHLTAMCSVCINPVFYGFLNRNFQRDLRAFRLCKIVSTRENEYDMVAMSTVNTDVSKMSLKMSSLDL", "length": 380 }, "evidence": [ { "id": "A0A4X1TYG4", "url": "https://omabrowser.org/oma/group/A0A4X1TYG4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3I6N9-1", "protein_name": "Neuropeptide Y receptor type 1", "gene_name": "Npy1r", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNSTLFSQVENHSFHYNSSETSPLLAFENDDCHLPLAVIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGETMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPSNRHAYIGIAVIWFLAVASSLPFLIYQVLTDEPFQNVTLAAFKDKYVCFDKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNSMMDKMRDSKHRCSETKRINVMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPIAFKKINMDDNEKI", "length": 382 }, "evidence": [ { "id": "A0A4X1TYG4", "url": "https://omabrowser.org/oma/group/A0A4X1TYG4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P21555-1", "protein_name": "Neuropeptide Y receptor type 1", "gene_name": "Npy1r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSTLFSRVENYSVHYNVSENSPFLAFENDDCHLPLAVIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAVMCLPFTFVYTLMDHWVFGETMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYIGITVIWVLAVASSLPFVIYQILTDEPFQNVSLAAFKDKYVCFDKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKIRDSKYRSSETKRINVMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKISMNDNEKI", "length": 382 }, "evidence": [ { "id": "A0A4X1TYG4", "url": "https://omabrowser.org/oma/group/A0A4X1TYG4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P25929-1", "protein_name": "Neuropeptide Y receptor type 1", "gene_name": "NPY1R", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI", "length": 384 }, "evidence": [ { "id": "A0A4X1TYG4", "url": "https://omabrowser.org/oma/group/A0A4X1TYG4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q04573-1", "protein_name": "Neuropeptide Y receptor type 1", "gene_name": "Npy1r", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSTLFSKVENHSIHYNASENSPLLAFENDDCHLPLAVIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAVMCLPFTFVYTLMDHWVFGETMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYIGITVIWVLAVASSLPFVIYQILTDEPFQNVSLAAFKDKYVCFDKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKIRDSKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKISMNDNEKV", "length": 382 }, "evidence": [ { "id": "A0A4X1TYG4", "url": "https://omabrowser.org/oma/group/A0A4X1TYG4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1RMU8-1", "protein_name": "Neuropeptide Y receptor type 1", "gene_name": "NPY1R", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNSTSFSQVENHSIYYNFSEKNSRFLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVLTDEPFQNVTLDAFKDKYVCFDKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYVRLKRRNSMMDKMRDNKYRSSEAKRINIMLLSIVVAFAVCWLPLTIFNTVFDWDHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFSFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVALKKIHTDDNEKI", "length": 383 }, "evidence": [ { "id": "A0A4X1TYG4", "url": "https://omabrowser.org/oma/group/A0A4X1TYG4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4" } ], "pmid": "" }, { "name": "peptide YY receptor activity", "id": "GO:0001601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001601", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4" } ], "pmid": "" }, { "name": "pancreatic polypeptide receptor activity", "id": "GO:0001602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001602", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway", "id": "GO:0007193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007193", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4" } ], "pmid": "" }, { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4" } ], "pmid": "" }, { "name": "cellular response to hormone stimulus", "id": "GO:0032870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032870", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4" } ], "pmid": "" }, { "name": "outflow tract morphogenesis", "id": "GO:0003151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003151", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYG4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TYG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYG4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 320, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 17, "end_pos": 19 }, { "start_pos": 186, "end_pos": 188 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TYR3-1", "uniprot_ac": "A0A4X1TYR3", "uniprot_id": "A0A4X1TYR3_PIG", "mass": { "chemical_mass": 9477.0, "monoisotopic_mass": 9477.0 }, "refseq": { "ac": "XP_003480386", "name": "40S ribosomal protein S27-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480386" }, "gene_names": [ { "name": "RPS27L", "type": "recommended", "evidence": [ { "id": "A0A4X1TYR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ] }, { "name": "RPS27L", "type": "synonym", "evidence": [ { "id": "XP_003480386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480386" } ] } ], "protein_names": [ { "name": "40S ribosomal protein S27", "type": "recommended", "evidence": [ { "id": "A0A4X1TYR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S27-like", "type": "synonym", "evidence": [ { "id": "XP_003480386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480386" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPS27L", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3", "locus": { "chromosome": "1", "start_pos": 108890283, "end_pos": 108881552, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000023158", "url": "https://www.ensembl.org/id/ENSSSCG00000023158" } ] } } ], "crossref": [ { "id": "A0A4X1TYR3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TYR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100738416", "url": "https://www.ncbi.nlm.nih.gov/gene/100738416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000592", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000592", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100738416", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738416", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERINMPL", "url": "https://omabrowser.org/oma/group/ERINMPL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TYR3", "url": "https://www.orthodb.org/?gene=A0A4X1TYR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11594", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11594", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01667", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01667", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003480386", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480386", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TYR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLARDLLHPSLEEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "length": 84, "header": "tr|A0A4X1TYR3-1|A0A4X1TYR3_PIG Isoform 1 of 40S ribosomal protein S27 OS=Sus scrofa OX=9823 GN=RPS27L PE=1 SV=1 CANONICAL=A0A4X1TYR3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TYR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3/entry#A0A4X1TYR3-1", "sequence": { "sequence": "MPLARDLLHPSLEEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "length": 84, "header": "tr|A0A4X1TYR3-1|A0A4X1TYR3_PIG Isoform 1 of 40S ribosomal protein S27 OS=Sus scrofa OX=9823 GN=RPS27L PE=1 SV=1 CANONICAL=A0A4X1TYR3-1" }, "locus": { "chromosome": "1", "start_pos": 108886159, "end_pos": 108881652, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027612.3", "url": "https://www.ensembl.org/id/ENSSSCT00000027612.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026227.1", "url": "https://www.ensembl.org/id/ENSSSCP00000026227.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100738416", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738416", "resource": "KEGG Pathway" }, { "id": "R-SSC-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-SSC-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-SSC-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-SSC-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-SSC-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-SSC-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-SSC-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-SSC-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-SSC-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-SSC-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q2TV39-1", "protein_name": "40S ribosomal protein S27", "gene_name": "RPS27L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPLARDLLHPSLEEERRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTILCQPTGGKARLTEGCSFRRKQH", "length": 84 }, "evidence": [ { "id": "A0A4X1TYR3", "url": "https://omabrowser.org/oma/group/A0A4X1TYR3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q3T0B7-1", "protein_name": "Small ribosomal subunit protein eS27-like", "gene_name": "RPS27L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLARDLLHPSLDEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "length": 84 }, "evidence": [ { "id": "A0A4X1TYR3", "url": "https://omabrowser.org/oma/group/A0A4X1TYR3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6ZWY3-1", "protein_name": "Small ribosomal subunit protein eS27-like", "gene_name": "Rps27l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLARDLLHPSLEEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "length": 84 }, "evidence": [ { "id": "A0A4X1TYR3", "url": "https://omabrowser.org/oma/group/A0A4X1TYR3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q71UM5-1", "protein_name": "Ribosomal protein eS27-like", "gene_name": "RPS27L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLARDLLHPSLEEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "length": 84 }, "evidence": [ { "id": "A0A4X1TYR3", "url": "https://omabrowser.org/oma/group/A0A4X1TYR3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "pmid": "" }, { "name": "translation activator activity", "id": "GO:0008494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008494", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "id": "GO:0042771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042771", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "pmid": "" }, { "name": "DNA damage response, signal transduction by p53 class mediator", "id": "GO:0030330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030330", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "pmid": "" }, { "name": "mitotic G1 DNA damage checkpoint signaling", "id": "GO:0031571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031571", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "pmid": "" }, { "name": "ribosomal small subunit assembly", "id": "GO:0000028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000028", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYR3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TYY4-1", "uniprot_ac": "A0A4X1TYY4", "uniprot_id": "A0A4X1TYY4_PIG", "mass": { "chemical_mass": 22007.0, "monoisotopic_mass": 22007.0 }, "refseq": { "ac": "NP_001231477", "name": "AP-3 complex subunit sigma-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231477" }, "gene_names": [ { "name": "AP3S2", "type": "recommended", "evidence": [ { "id": "A0A4X1TYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4" } ] }, { "name": "AP3S2", "type": "synonym", "evidence": [ { "id": "NP_001231477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231477" } ] } ], "protein_names": [ { "name": "AP-3 complex subunit sigma-2", "type": "synonym", "evidence": [ { "id": "NP_001231477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231477" } ] }, { "name": "Adaptor-related protein complex 3, sigma 2 subunit", "type": "synonym", "evidence": [ { "id": "A0A4X1TYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8D1AM03#function" }, { "database": "UniProtKB", "id": "ARBA00025605", "url": "https://www.uniprot.org/uniprotkb/ARBA00025605#function" }, { "database": "UniProtKB", "id": "A0A8W4FI98", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI98#function" }, { "database": "UniProtKB", "id": "A0A4X1TYY4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4#function" }, { "database": "UniProtKB", "id": "A0A4X1U1C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1C5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYY4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AP3S2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4", "locus": { "chromosome": "7", "start_pos": 55391913, "end_pos": 55469858, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000030174", "url": "https://www.ensembl.org/id/ENSSSCG00000030174" } ] } } ], "crossref": [ { "id": "A0A4X1TYY4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TYY4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14834", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14834", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100153862", "url": "https://www.ncbi.nlm.nih.gov/gene/100153862", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153862", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153862", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNDQGKP", "url": "https://omabrowser.org/oma/group/MNDQGKP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TYY4", "url": "https://www.orthodb.org/?gene=A0A4X1TYY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231477", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231477", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TYY4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TYY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U1C5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U1C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1C5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8D1AM03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1AM03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1AM03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI98", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNKLEKSEGGLSAAPARAVSAVKNINLPEMPRNINIGDLNIKVPNLSQFV", "length": 193, "header": "tr|A0A4X1TYY4-1|A0A4X1TYY4_PIG Isoform 1 of Adaptor-related protein complex 3, sigma 2 subunit OS=Sus scrofa OX=9823 GN=AP3S2 PE=3 SV=1 CANONICAL=A0A4X1TYY4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TYY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4/entry#A0A4X1TYY4-1", "sequence": { "sequence": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNKLEKSEGGLSAAPARAVSAVKNINLPEMPRNINIGDLNIKVPNLSQFV", "length": 193, "header": "tr|A0A4X1TYY4-1|A0A4X1TYY4_PIG Isoform 1 of Adaptor-related protein complex 3, sigma 2 subunit OS=Sus scrofa OX=9823 GN=AP3S2 PE=3 SV=1 CANONICAL=A0A4X1TYY4-1" }, "locus": { "chromosome": "7", "start_pos": 55462268, "end_pos": 55396705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025884.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025884.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024872.4", "url": "https://www.ensembl.org/id/ENSSSCP00000024872.4" } ] } }, { "isoform_ac": "A0A4X1U1C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4/entry#A0A4X1U1C5-1", "sequence": { "sequence": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVHYILQEVVMGGMVLETNMNEIVAQIEAQNKLEKSEGGLSAAPARAVSAVKNINLPEMPRNINIGDLNIKVPNLSQFV", "length": 169, "header": "tr|A0A4X1U1C5-1|A0A4X1U1C5_PIG Computationally mapped isoform of Adaptor-related protein complex 3, sigma 2 subunit OS=Sus scrofa OX=9823 GN=AP3S2 PE=1 SV=1 CANONICAL=A0A4X1TYY4-1" }, "locus": { "chromosome": "7", "start_pos": 55462268, "end_pos": 55396705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059305.2", "url": "https://www.ensembl.org/id/ENSSSCT00000059305.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049304.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049304.2" } ] } }, { "isoform_ac": "A0A8D1AM03-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4/entry#A0A8D1AM03-1", "sequence": { "sequence": "AIFICFSDVLGFAPGGILKQTPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNKLEKSEGGLSAAPARAVSAVKNINLPEMPRNINIGDLNIKVPNLSQFV", "length": 191, "header": "tr|A0A8D1AM03-1|A0A4X1TYY4_PIG Computationally mapped isoform of Adaptor-related protein complex 3, sigma 2 subunit OS=Sus scrofa OX=9823 GN=AP3S2 PE=3 SV=1 CANONICAL=A0A4X1TYY4-1" }, "locus": { "chromosome": "7", "start_pos": 55462648, "end_pos": 55396705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056139.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056139.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040490.1", "url": "https://www.ensembl.org/id/ENSSSCP00000040490.1" } ] } }, { "isoform_ac": "A0A8W4FI98-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4/entry#A0A8W4FI98-1", "sequence": { "sequence": "MKHLSLDPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNKLEKSEGGLSAAPARAVSAVKNINLPEMPRNINIGDLNIKVPNLSQFV", "length": 177, "header": "tr|A0A8W4FI98-1|A0A4X1TYY4_PIG Computationally mapped isoform of Adaptor-related protein complex 3, sigma 2 subunit OS=Sus scrofa OX=9823 GN=AP3S2 PE=3 SV=1 CANONICAL=A0A4X1TYY4-1" }, "locus": { "chromosome": "7", "start_pos": 55469794, "end_pos": 55396705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101525.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101525.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079053.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079053.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8D1AM03" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153862", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153862", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P59780-1", "protein_name": "AP-3 complex subunit sigma-2", "gene_name": "AP3S2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIGDLNIKVPNLSQFV", "length": 193 }, "evidence": [ { "id": "A0A4X1TYY4", "url": "https://omabrowser.org/oma/group/A0A4X1TYY4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1JQA3-1", "protein_name": "AP-3 complex subunit sigma-2", "gene_name": "AP3S2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEMPRNINIGDLNIKVPNLSQFV", "length": 193 }, "evidence": [ { "id": "A0A4X1TYY4", "url": "https://omabrowser.org/oma/group/A0A4X1TYY4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BSZ2-1", "protein_name": "AP-3 complex subunit sigma-2", "gene_name": "Ap3s2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIGDLNIKVPNLSQFV", "length": 193 }, "evidence": [ { "id": "A0A4X1TYY4", "url": "https://omabrowser.org/oma/group/A0A4X1TYY4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W1E8-1", "protein_name": "Orange", "gene_name": "or", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIKAILVFNNHGKPRLSKFYQYFDESLQQQIIKETFQLVSKRDDNVCNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHADAVHHILSELVMGGMVLQTNMNDIMARIEEQNKIVKQEAGISAAPARAVSAVKSMNIPQQIKDIKLPDLPQAIKDFKF", "length": 191 }, "evidence": [ { "id": "A0A4X1TYY4", "url": "https://omabrowser.org/oma/group/A0A4X1TYY4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYY4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYY4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4" } ], "pmid": "" }, { "name": "AP-3 adaptor complex", "id": "GO:0030123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030123", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYY4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYY4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYY4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYY4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4" } ], "pmid": "" }, { "name": "anterograde synaptic vesicle transport", "id": "GO:0048490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048490", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYY4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TYY4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TYY4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TZ25-1", "uniprot_ac": "A0A4X1TZ25", "uniprot_id": "A0A4X1TZ25_PIG", "mass": { "chemical_mass": 34739.0, "monoisotopic_mass": 34739.0 }, "refseq": {}, "gene_names": [ { "name": "OR2G3", "type": "recommended", "evidence": [ { "id": "A0A4X1TZ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TZ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OR2G3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25", "locus": { "chromosome": "2", "start_pos": 56615141, "end_pos": 56616070, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013944", "url": "https://www.ensembl.org/id/ENSSSCG00000013944" } ] } } ], "crossref": [ { "id": "A0A4X1TZ25", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TZ25", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RLNHFIC", "url": "https://omabrowser.org/oma/group/RLNHFIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1TZ25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TZ25-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKNNESSLVGFVLLGFSDHPRLEAVLFVFVLFFYLLTLVGNFTIIIISYLDASLHTPMYFFLSNLSLLDLCFTTSLVPQTLVNFRGPEKTITFGGCVVQLYISLALGSTECILLAVMALDRYVAVCKPLHYVVIMNPRLCQQLASISWLSGLANSLIHATFTLQLPFCNNHRLDHFICEVPALLKLACVDTTINELVLFVVSVLFLLIPPALILISYGFITQAVLRIKSVEARNKAFSTCSSHLTVVTIFYGTIIYMYLQPSNSYAQDQGKFISLFYTMVTPTLNPIIYTLRNKDVKDALKKLLSGKLF", "length": 310, "header": "tr|A0A4X1TZ25-1|A0A4X1TZ25_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR2G3 PE=3 SV=1 CANONICAL=A0A4X1TZ25-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TZ25-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25/entry#A0A4X1TZ25-1", "sequence": { "sequence": "MEKNNESSLVGFVLLGFSDHPRLEAVLFVFVLFFYLLTLVGNFTIIIISYLDASLHTPMYFFLSNLSLLDLCFTTSLVPQTLVNFRGPEKTITFGGCVVQLYISLALGSTECILLAVMALDRYVAVCKPLHYVVIMNPRLCQQLASISWLSGLANSLIHATFTLQLPFCNNHRLDHFICEVPALLKLACVDTTINELVLFVVSVLFLLIPPALILISYGFITQAVLRIKSVEARNKAFSTCSSHLTVVTIFYGTIIYMYLQPSNSYAQDQGKFISLFYTMVTPTLNPIIYTLRNKDVKDALKKLLSGKLF", "length": 310, "header": "tr|A0A4X1TZ25-1|A0A4X1TZ25_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=OR2G3 PE=3 SV=1 CANONICAL=A0A4X1TZ25-1" }, "locus": { "chromosome": "2", "start_pos": 56616070, "end_pos": 56615141, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015230.3", "url": "https://www.ensembl.org/id/ENSSSCT00000015230.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014824.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014824.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 282, "start_aa": "Thr", "end_pos": 282, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr282", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1MRX8-1", "protein_name": "Olfactory receptor", "gene_name": "OR2G3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKANESSLIGFVLLGFSDHPRLEAVLFVFVLLFYLLTLVGNITIIIISYLDPPLHTPMYFFLGNLSFLDICFTTSLAPQTLVNLRGPEKTITYGGCVVQLCISLALGSTECILLVVMALDRYVAVCKPLHYVVIMNPRLCQQLAFISWLSGLASSLIHATFTLQLPFCGNHRLDHFICEVPALLKLACVDTTINELVLFVVSILFLLIPPALILISYGFITQAVLRLKSVEARRKAFSTCSSHLTVVIIFYGTIIYMYLQPINSYAQDQGKFISLFYTMVTPTLNPIIYTLRNKDVKDALKKLLTGKLCFLQT", "length": 314 }, "evidence": [ { "id": "A0A4X1TZ25", "url": "https://omabrowser.org/oma/group/A0A4X1TZ25/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8NGZ4-1", "protein_name": "Olfactory receptor 2G3", "gene_name": "OR2G3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLGNESSLMDFILLGFSDHPRLEAVLFVFVLFFYLLTLVGNFTIIIISYLDPPLHTPMYFFLSNLSLLDICFTTSLAPQTLVNLQRPKKTITYGGCVAQLYISLALGSTECILLADMALDRYIAVCKPLHYVVIMNPRLCQQLASISWLSGLASSLIHATFTLQLPLCGNHRLDHFICEVPALLKLACVDTTVNELVLFVVSVLFVVIPPALISISYGFITQAVLRIKSVEARHKAFSTCSSHLTVVIIFYGTIIYVYLQPSDSYAQDQGKFISLFYTMVTPTLNPIIYTLRNKDMKEALRKLLSGKL", "length": 309 }, "evidence": [ { "id": "A0A4X1TZ25", "url": "https://omabrowser.org/oma/group/A0A4X1TZ25/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ25", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TZ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ25" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 282 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TZ73-1", "uniprot_ac": "A0A4X1TZ73", "uniprot_id": "A0A4X1TZ73_PIG", "mass": { "chemical_mass": 11620.0, "monoisotopic_mass": 11620.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Cytochrome c domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A4X1TZ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ73", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73#function" }, { "database": "UniProtKB", "id": "RU004427", "url": "https://www.uniprot.org/uniprotkb/RU004427#function" }, { "database": "UniProtKB", "id": "ARBA00002555", "url": "https://www.uniprot.org/uniprotkb/ARBA00002555#function" } ] }, { "annotation": "Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ73", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73#function" }, { "database": "UniProtKB", "id": "ARBA00025038", "url": "https://www.uniprot.org/uniprotkb/ARBA00025038#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ73", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73", "locus": {} } ], "crossref": [ { "id": "A0A4X1TZ73", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TZ73", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MAIMAIS", "url": "https://omabrowser.org/oma/group/MAIMAIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11961", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11961", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-111457", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111457", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-111458", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111458", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-111459", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111459", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-111461", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111461", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2151201", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2151201", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3299685", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3299685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5620971", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620971", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9627069", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9627069", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9707564", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9707564", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TZ73", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TZ73-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGWKTGQAPGFTYTDANKSKGVTWGEETLMEYLENPKKCIPGMKMIFAGIKKKGEREDLGAYLKKATNE", "length": 105, "header": "tr|A0A4X1TZ73-1|A0A4X1TZ73_PIG Isoform 1 of Cytochrome c domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1TZ73-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TZ73-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73/entry#A0A4X1TZ73-1", "sequence": { "sequence": "MGDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGWKTGQAPGFTYTDANKSKGVTWGEETLMEYLENPKKCIPGMKMIFAGIKKKGEREDLGAYLKKATNE", "length": 105, "header": "tr|A0A4X1TZ73-1|A0A4X1TZ73_PIG Isoform 1 of Cytochrome c domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1TZ73-1" }, "locus": { "chromosome": "13", "start_pos": 22115217, "end_pos": 22114903, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064128.1", "url": "https://www.ensembl.org/id/ENSSSCT00000064128.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049542.1", "url": "https://www.ensembl.org/id/ENSSSCP00000049542.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ73", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-111457", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111457", "resource": "Reactome", "description": "Release of apoptotic factors from the mitochondria" }, { "id": "R-SSC-111458", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111458", "resource": "Reactome", "description": "Formation of apoptosome" }, { "id": "R-SSC-111459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111459", "resource": "Reactome", "description": "Activation of caspases through apoptosome-mediated cleavage" }, { "id": "R-SSC-111461", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111461", "resource": "Reactome", "description": "Cytochrome c-mediated apoptotic response" }, { "id": "R-SSC-2151201", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2151201", "resource": "Reactome", "description": "Transcriptional activation of mitochondrial biogenesis" }, { "id": "R-SSC-3299685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3299685", "resource": "Reactome", "description": "Detoxification of Reactive Oxygen Species" }, { "id": "R-SSC-5620971", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620971", "resource": "Reactome", "description": "Pyroptosis" }, { "id": "R-SSC-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-SSC-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-SSC-9627069", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9627069", "resource": "Reactome", "description": "Regulation of the apoptosome activity" }, { "id": "R-SSC-9707564", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9707564", "resource": "Reactome", "description": "Cytoprotection by HMOX1" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ73", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "electron transfer activity", "id": "GO:0009055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009055", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ73", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ73", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ73", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ73", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73" } ], "pmid": "" }, { "name": "mitochondrial electron transport, cytochrome c to oxygen", "id": "GO:0006123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006123", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ73", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73" } ], "pmid": "" }, { "name": "mitochondrial electron transport, ubiquinol to cytochrome c", "id": "GO:0006122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006122", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ73", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TZ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ73" }, { "id": "PS51007", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51007" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytochrome c", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 103, "start_aa": "Gly", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TZ80-1", "uniprot_ac": "A0A4X1TZ80", "uniprot_id": "A0A4X1TZ80_PIG", "mass": { "chemical_mass": 38686.0, "monoisotopic_mass": 38686.0 }, "refseq": { "ac": "XP_003125637", "name": "protein Wnt-8b isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125637" }, "gene_names": [ { "name": "WNT8B", "type": "recommended", "evidence": [ { "id": "A0A4X1TZ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80" } ] }, { "name": "WNT8B", "type": "synonym", "evidence": [ { "id": "XP_003125637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125637" } ] } ], "protein_names": [ { "name": "Protein Wnt", "type": "recommended", "evidence": [ { "id": "A0A4X1TZ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80/entry#names_and_taxonomy" } ] }, { "name": "protein Wnt-8b isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003125637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125637" } ] } ], "function": [ { "annotation": "Ligand for members of the frizzled family of seven transmembrane receptors.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ80", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80#function" }, { "database": "UniProtKB", "id": "RU003500", "url": "https://www.uniprot.org/uniprotkb/RU003500#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ80", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "WNT8B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80", "locus": { "chromosome": "14", "start_pos": 111589893, "end_pos": 111562489, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006164", "url": "https://www.ensembl.org/id/ENSSSCG00000006164" } ] } } ], "crossref": [ { "id": "A0A4X1TZ80", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TZ80", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19352", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19352", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513655", "url": "https://www.ncbi.nlm.nih.gov/gene/100513655", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513655", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513655", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TZ80", "url": "https://www.orthodb.org/?gene=A0A4X1TZ80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12027:SF94", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12027:SF94", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00110", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00110", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3238698", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3238698", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4641262", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4641262", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003125637", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125637", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TZ80", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TZ80-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLMKPSVCIFLFTCVLQLSHTWSVNNFLMTGPKAYLIYSSSVAAGAQSGIEECKYQFAWDRWNCPERALQLSSHGGLRSANRETAFVHAISSAGVMYTLTRNCSLGDFDNCGCDDSRNGQLGGQGWLWGGCSDNVGFGEAISKQFVDALETGQDARAAMNLHNNEAGRKAVKGTMKRTCKCHGVSGSCTTQTCWLQLPEFREVGAHLKEKYHAALKVDLLQGAGNSAAGRGAIADTFRSISTRELVHLEDSPDYCLENKTLGLLGTEGRECLRRGRALGRWERRSCRRLCGDCGLSVEERRAETVSSCNCKFHWCCAVRCEQCRRRVTKYFCSRAERPPGGAAHKPGRKP", "length": 351, "header": "tr|A0A4X1TZ80-1|A0A4X1TZ80_PIG Isoform 1 of Protein Wnt OS=Sus scrofa OX=9823 GN=WNT8B PE=3 SV=1 CANONICAL=A0A4X1TZ80-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TZ80-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80/entry#A0A4X1TZ80-1", "sequence": { "sequence": "MLLMKPSVCIFLFTCVLQLSHTWSVNNFLMTGPKAYLIYSSSVAAGAQSGIEECKYQFAWDRWNCPERALQLSSHGGLRSANRETAFVHAISSAGVMYTLTRNCSLGDFDNCGCDDSRNGQLGGQGWLWGGCSDNVGFGEAISKQFVDALETGQDARAAMNLHNNEAGRKAVKGTMKRTCKCHGVSGSCTTQTCWLQLPEFREVGAHLKEKYHAALKVDLLQGAGNSAAGRGAIADTFRSISTRELVHLEDSPDYCLENKTLGLLGTEGRECLRRGRALGRWERRSCRRLCGDCGLSVEERRAETVSSCNCKFHWCCAVRCEQCRRRVTKYFCSRAERPPGGAAHKPGRKP", "length": 351, "header": "tr|A0A4X1TZ80-1|A0A4X1TZ80_PIG Isoform 1 of Protein Wnt OS=Sus scrofa OX=9823 GN=WNT8B PE=3 SV=1 CANONICAL=A0A4X1TZ80-1" }, "locus": { "chromosome": "14", "start_pos": 111587702, "end_pos": 111562658, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006758.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006758.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006575.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006575.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ80", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513655", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513655", "resource": "KEGG Pathway" }, { "id": "R-SSC-3238698", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3238698", "resource": "Reactome", "description": "WNT ligand biogenesis and trafficking" }, { "id": "R-SSC-4641262", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4641262", "resource": "Reactome", "description": "Disassembly of the destruction complex and recruitment of AXIN to the membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ80", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80" } ], "pmid": "" }, { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ80", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ80", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ80", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ80", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80" } ], "pmid": "" }, { "name": "cell fate commitment", "id": "GO:0045165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZ80", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZ80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 259, "end_pos": 261 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TZD1-1", "uniprot_ac": "A0A4X1TZD1", "uniprot_id": "A0A4X1TZD1_PIG", "mass": { "chemical_mass": 35761.0, "monoisotopic_mass": 35761.0 }, "refseq": { "ac": "XP_020940734", "name": "olfactory receptor 2L13", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940734" }, "gene_names": [ { "name": "LOC100523426", "type": "recommended", "evidence": [ { "id": "A0A4X1TZD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1" } ] }, { "name": "LOC100523426", "type": "synonym", "evidence": [ { "id": "XP_020940734", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940734" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TZD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2L13", "type": "synonym", "evidence": [ { "id": "XP_020940734", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940734" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZD1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZD1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100523426", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1", "locus": {} } ], "crossref": [ { "id": "A0A4X1TZD1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TZD1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523426", "url": "https://www.ncbi.nlm.nih.gov/gene/100523426", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523426", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523426", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ssc:110255196", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255196", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAKMVIG", "url": "https://omabrowser.org/oma/group/CAKMVIG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TZD1", "url": "https://www.orthodb.org/?gene=A0A4X1TZD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020940734", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940734", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TZD1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TZD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKWNQTSNDFILLGLFPQNQTGLLLLFFIIFIFFLASVGNSAMIYLIRSDPRLHTPMYFLLSQLSLMDLMYLSTTVPKMVFNFLSGQKGISYLGCGVQSFFFLTMACSEGLLLASMAYDRYVAICHPLHYCIRMSKRMCVKMIMGSWILGSINSLAHTVYALHIPYCQSRAINHFFCDIPAMLSLACMDTWVYEYMVFVSTSLFLLLPFLGITASYGWVLFAVYHMRSKDGRKKAFTTCSTHLTVVTFYYAPFVYTYLRPSNLRSPAEDKILAVFYTILTPMLNPIIYSLRNKEVLGAMMRVFGIYSSIKL", "length": 312, "header": "tr|A0A4X1TZD1-1|A0A4X1TZD1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100523426 PE=3 SV=1 CANONICAL=A0A4X1TZD1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TZD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1/entry#A0A4X1TZD1-1", "sequence": { "sequence": "MEKWNQTSNDFILLGLFPQNQTGLLLLFFIIFIFFLASVGNSAMIYLIRSDPRLHTPMYFLLSQLSLMDLMYLSTTVPKMVFNFLSGQKGISYLGCGVQSFFFLTMACSEGLLLASMAYDRYVAICHPLHYCIRMSKRMCVKMIMGSWILGSINSLAHTVYALHIPYCQSRAINHFFCDIPAMLSLACMDTWVYEYMVFVSTSLFLLLPFLGITASYGWVLFAVYHMRSKDGRKKAFTTCSTHLTVVTFYYAPFVYTYLRPSNLRSPAEDKILAVFYTILTPMLNPIIYSLRNKEVLGAMMRVFGIYSSIKL", "length": 312, "header": "tr|A0A4X1TZD1-1|A0A4X1TZD1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100523426 PE=3 SV=1 CANONICAL=A0A4X1TZD1-1" }, "locus": { "chromosome": "2", "start_pos": 54976046, "end_pos": 54975111, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101626.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101626.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075730.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075730.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZD1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523426", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523426", "resource": "KEGG Pathway" }, { "id": "ssc:110255196", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255196", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8VF05-1", "protein_name": "Olfactory receptor", "gene_name": "Or2l13b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKWNQSSSDFILLGLLPQNQTGLLLMMLIILVFFLALFGNSAMIHLIRVDPRLHTPMYFLLSQLSLMDLMYISTTVPKMAFNFLSGQKNISFLGCGVQSFFFLTMAGSEGLLLASMAYDRFVAICHPLHYPIRMSKIMCLKMIIGSWILGSINSLAHSIYALHIPYCHSRSINHFFCDVPAMLPLACMDTWVYEYMVFVSTSLFLLLPFLGITASYGRVLFAVFHMRSKEGKKKAFTTCSTHLTVVTFYYAPFVYTYLRPRSLRSPTEDKILTVFYTILTPMLNPIIYSLRNKEVLGAMTRVLGTFSSMKP", "length": 312 }, "evidence": [ { "id": "A0A4X1TZD1", "url": "https://omabrowser.org/oma/group/A0A4X1TZD1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZD1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZD1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZD1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZD1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TZD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZD1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TZI2-1", "uniprot_ac": "A0A4X1TZI2", "uniprot_id": "A0A4X1TZI2_PIG", "mass": { "chemical_mass": 34906.0, "monoisotopic_mass": 34906.0 }, "refseq": { "ac": "XP_003354000", "name": "olfactory receptor 4C46-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354000" }, "gene_names": [ { "name": "LOC100620421", "type": "recommended", "evidence": [ { "id": "A0A4X1TZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2" } ] }, { "name": "LOC100620421", "type": "synonym", "evidence": [ { "id": "XP_003354000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354000" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4C46-like", "type": "synonym", "evidence": [ { "id": "XP_003354000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354000" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZI2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZI2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100620421", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2", "locus": {} } ], "crossref": [ { "id": "A0A4X1TZI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TZI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100620421", "url": "https://www.ncbi.nlm.nih.gov/gene/100620421", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100620421", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620421", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WHYTSIM", "url": "https://omabrowser.org/oma/group/WHYTSIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TZI2", "url": "https://www.orthodb.org/?gene=A0A4X1TZI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003354000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003354000", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TZI2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TZI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENRNNVTEFILLGLTRNPKTQKIIFVVFLIIYIVSVVGNVLTMVIVTASPLLKSPMYFFLAHLSFIDASYSSVNTPKLIVDLLHERKTSPFNECMTQIFGQHLFVGVDIILLTVMAYDRYVAICKPLHYITIMNWQVCWLLVGVVWVGGFLHSTIQILFIFRLPFCGPNIIDHFMCDLNPLLNLACTDTHTLGLFVALNSGFICLLNFVLLIGSYVVILLSLRTHSLEARHKALSTCVSHITVVILFFVPCIFVYLRPAANLPIDKAVTIFYTMITPMLNPLIYTLRNAQMKNAIKNLCSRKAISGDK", "length": 309, "header": "tr|A0A4X1TZI2-1|A0A4X1TZI2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100620421 PE=3 SV=1 CANONICAL=A0A4X1TZI2-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TZI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2/entry#A0A4X1TZI2-1", "sequence": { "sequence": "MENRNNVTEFILLGLTRNPKTQKIIFVVFLIIYIVSVVGNVLTMVIVTASPLLKSPMYFFLAHLSFIDASYSSVNTPKLIVDLLHERKTSPFNECMTQIFGQHLFVGVDIILLTVMAYDRYVAICKPLHYITIMNWQVCWLLVGVVWVGGFLHSTIQILFIFRLPFCGPNIIDHFMCDLNPLLNLACTDTHTLGLFVALNSGFICLLNFVLLIGSYVVILLSLRTHSLEARHKALSTCVSHITVVILFFVPCIFVYLRPAANLPIDKAVTIFYTMITPMLNPLIYTLRNAQMKNAIKNLCSRKAISGDK", "length": 309, "header": "tr|A0A4X1TZI2-1|A0A4X1TZI2_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100620421 PE=3 SV=1 CANONICAL=A0A4X1TZI2-1" }, "locus": { "chromosome": "2", "start_pos": 50107002, "end_pos": 50106076, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087232.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087232.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065443.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065443.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZI2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100620421", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620421", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZI2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZI2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZI2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZI2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TZJ1-1", "uniprot_ac": "A0A4X1TZJ1", "uniprot_id": "A0A4X1TZJ1_PIG", "mass": { "chemical_mass": 35939.0, "monoisotopic_mass": 35939.0 }, "refseq": { "ac": "XP_020941136", "name": "olfactory receptor 8K3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941136" }, "gene_names": [ { "name": "LOC110259732", "type": "recommended", "evidence": [ { "id": "A0A4X1TZJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1" } ] }, { "name": "LOC110259732", "type": "synonym", "evidence": [ { "id": "XP_020941136", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941136" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1TZJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8K3-like", "type": "synonym", "evidence": [ { "id": "XP_020941136", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941136" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259732", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1", "locus": {} } ], "crossref": [ { "id": "A0A4X1TZJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TZJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "110259732", "url": "https://www.ncbi.nlm.nih.gov/gene/110259732", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110259732", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259732", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FCAVQFA", "url": "https://omabrowser.org/oma/group/FCAVQFA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TZJ1", "url": "https://www.orthodb.org/?gene=A0A4X1TZJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020941136", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941136", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TZJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKHNLTVLSKFILMGITDHPELQLPLFGMFLLIYMISVVGNLGMVILTKVDSRLQTPMYFFLRHLSFTDLGYSTTIGPKMLESFVVAENTISYYLCATQGAFYIVFIISEFFILSAMSYDRYVAICHPLLYTIMMSQRVCCVLVSIPYFYSIFLSLFTTVKIFNLSFCGYNIIKHFYCDSLSLLPLLCSNTYDIELIILLFSAFNLISSLLIVLVSYLLILVAIFRMNSSGGRQKALSTCGSHLTVITVFYGTLLFMYMQPKYSHSFDTDKVTSIFYTLIIPMLNPLIYSLRNKDVKYALHKLWEKICSMFS", "length": 313, "header": "tr|A0A4X1TZJ1-1|A0A4X1TZJ1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259732 PE=3 SV=1 CANONICAL=A0A4X1TZJ1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TZJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1/entry#A0A4X1TZJ1-1", "sequence": { "sequence": "MEKHNLTVLSKFILMGITDHPELQLPLFGMFLLIYMISVVGNLGMVILTKVDSRLQTPMYFFLRHLSFTDLGYSTTIGPKMLESFVVAENTISYYLCATQGAFYIVFIISEFFILSAMSYDRYVAICHPLLYTIMMSQRVCCVLVSIPYFYSIFLSLFTTVKIFNLSFCGYNIIKHFYCDSLSLLPLLCSNTYDIELIILLFSAFNLISSLLIVLVSYLLILVAIFRMNSSGGRQKALSTCGSHLTVITVFYGTLLFMYMQPKYSHSFDTDKVTSIFYTLIIPMLNPLIYSLRNKDVKYALHKLWEKICSMFS", "length": 313, "header": "tr|A0A4X1TZJ1-1|A0A4X1TZJ1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259732 PE=3 SV=1 CANONICAL=A0A4X1TZJ1-1" }, "locus": { "chromosome": "2", "start_pos": 50210137, "end_pos": 50209199, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058499.2", "url": "https://www.ensembl.org/id/ENSSSCT00000058499.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050238.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050238.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110259732", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259732", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZJ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1TZJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZJ1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1TZQ3-1", "uniprot_ac": "A0A4X1TZQ3", "uniprot_id": "A0A4X1TZQ3_PIG", "mass": { "chemical_mass": 14533.0, "monoisotopic_mass": 14533.0 }, "refseq": { "ac": "XP_020944028", "name": "profilin-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944028" }, "gene_names": [ { "name": "PFN4", "type": "recommended", "evidence": [ { "id": "A0A4X1TZQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3" } ] }, { "name": "PFN4", "type": "synonym", "evidence": [ { "id": "XP_020944028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944028" } ] } ], "protein_names": [ { "name": "Profilin", "type": "recommended", "evidence": [ { "id": "A0A4X1TZQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3/entry#names_and_taxonomy" } ] }, { "name": "profilin-4", "type": "synonym", "evidence": [ { "id": "XP_020944028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944028" } ] } ], "function": [ { "annotation": "Involved in male fertility. Required for manchette development and acrosome biogenesis during spermiogenesis. Binds in vitro to phospholipids, including phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA). Contrary to other profilin family members, does not bind to actin in vitro.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZQ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3#function" }, { "database": "UniProtKB", "id": "ARBA00059169", "url": "https://www.uniprot.org/uniprotkb/ARBA00059169#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZQ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PFN4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3", "locus": { "chromosome": "3", "start_pos": 114585194, "end_pos": 114578199, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008585", "url": "https://www.ensembl.org/id/ENSSSCG00000008585" } ] } } ], "crossref": [ { "id": "A0A4X1TZQ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1TZQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00148", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00148", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521444", "url": "https://www.ncbi.nlm.nih.gov/gene/100521444", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521444", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521444", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QGQKFML", "url": "https://omabrowser.org/oma/group/QGQKFML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1TZQ3", "url": "https://www.orthodb.org/?gene=A0A4X1TZQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11604", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11604", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11604:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11604:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00235", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00235", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020944028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944028", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TZQ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TZQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHLQNLLLDTLLGTKHVDCAALIKLQERSLCVASPGFSVMPSDIRTLVNVFAKNPLKARREGLYFKEKDYKCVRADDYSLYAKNENTGVVVVKTHLYLLVATYTNGMYPSVCVEATEKLGEYLRRKGN", "length": 129, "header": "tr|A0A4X1TZQ3-1|A0A4X1TZQ3_PIG Isoform 1 of Profilin OS=Sus scrofa OX=9823 GN=PFN4 PE=3 SV=1 CANONICAL=A0A4X1TZQ3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TZQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3/entry#A0A4X1TZQ3-1", "sequence": { "sequence": "MSHLQNLLLDTLLGTKHVDCAALIKLQERSLCVASPGFSVMPSDIRTLVNVFAKNPLKARREGLYFKEKDYKCVRADDYSLYAKNENTGVVVVKTHLYLLVATYTNGMYPSVCVEATEKLGEYLRRKGN", "length": 129, "header": "tr|A0A4X1TZQ3-1|A0A4X1TZQ3_PIG Isoform 1 of Profilin OS=Sus scrofa OX=9823 GN=PFN4 PE=3 SV=1 CANONICAL=A0A4X1TZQ3-1" }, "locus": { "chromosome": "3", "start_pos": 114584190, "end_pos": 114579072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009395.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009395.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009155.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009155.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZQ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521444", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521444", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061HWX0-1", "protein_name": "Profilin", "gene_name": "Pfn4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSHLQNLLLDTLLGTKHVDGAALIKLHERSLCVASPGFSVMPNDVRTLVNGFAKNPLITRREGLYFREKDYKCVRADDYSLYAKNENTGVIVVKTHLYLLVATYTAGMYPSVCVEATEKLGEYLRKKGN", "length": 129 }, "evidence": [ { "id": "A0A4X1TZQ3", "url": "https://omabrowser.org/oma/group/A0A4X1TZQ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P07274-1", "protein_name": "Profilin", "gene_name": "PFY1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSWQAYTDNLIGTGKVDKAVIYSRAGDAVWATSGGLSLQPNEIGEIVQGFDNPAGLQSNGLHIQGQKFMLLRADDRSIYGRHDAEGVVCVRTKQTVIIAHYPPTVQAGEATKIVEQLADYLIGVQY", "length": 126 }, "evidence": [ { "id": "A0A4X1TZQ3", "url": "https://omabrowser.org/oma/group/A0A4X1TZQ3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P26199-1", "protein_name": "Profilin-1", "gene_name": "proA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSWQQYVDEQLTGAGLSQGAILGANDGGVWAKSSGINITKPEGDGIAALFKNPAEVFAKGALIGGVKYMGIKGDPQSIYGKKGATGCVLVRTGQAIIVGIYDDKVQPGSAALIVEKLGDYLRDNGY", "length": 126 }, "evidence": [ { "id": "A0A4X1TZQ3", "url": "https://omabrowser.org/oma/group/A0A4X1TZQ3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q2NKT1-1", "protein_name": "Profilin-4", "gene_name": "PFN4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSHLQNLLLDTLLGTKHVDSAALIKLQERSLCVASPGFSVMPSDVRTLVNGFAKNPLKTRREGLYFKEKDYKCVRADDYSLYAKNENTGVIVVKTHLYLLVATYSEGMYPSVCVEATEKLGDYLRRKGN", "length": 129 }, "evidence": [ { "id": "A0A4X1TZQ3", "url": "https://omabrowser.org/oma/group/A0A4X1TZQ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5IRJ7-1", "protein_name": "Profilin-4", "gene_name": "Pfn4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLQNLLLDTLLGTKHVDGAALIKLQEKTLCVTSPGFSVMPCDVRTLLNGFAKNPLLTRREGLYFREKDYKCVRADDCSLYAKKENTGVVVVKTHMYLLVATYTAGMYPSVCVEATEKLGEYLRKKGN", "length": 129 }, "evidence": [ { "id": "A0A4X1TZQ3", "url": "https://omabrowser.org/oma/group/A0A4X1TZQ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NHR9-1", "protein_name": "Profilin-4", "gene_name": "PFN4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSHLQSLLLDTLLGTKHVDSAALIKIQERSLCVASPGFNVTPSDVRTLVNGFAKNPLQARREGLYFKGKDYRCVRADEYSLYAKNENTGVVVVKTHLYLLVATYTEGMYPSICVEATESLGDYLRKKGS", "length": 129 }, "evidence": [ { "id": "A0A4X1TZQ3", "url": "https://omabrowser.org/oma/group/A0A4X1TZQ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D6I3-1", "protein_name": "Profilin-4", "gene_name": "Pfn4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHLQNLLLDTLLGTKHVDSAALIKLQEKTLCVTSPGFSVMPSDVRTLLNGFAKNPLLTRREGLYFKEKDYKCVRADDYSLYAKNENTGVVVVKTNMYLVVATYTAGMYPSVCVEATEKLGEYLRKKGN", "length": 129 }, "evidence": [ { "id": "A0A4X1TZQ3", "url": "https://omabrowser.org/oma/group/A0A4X1TZQ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WCU6-1", "protein_name": "Profilin", "gene_name": "pfn4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNPLPKLLEDCLISTKHVERAAVFVAKTCDITAASNFTVCLEEIQIFLDAFKHLNETMKKGLIFRDKPYTCVRADKHSIYAKNEGRGLILVRTALYVIVATYSQTMHPSICVEAVEKLGDYLREKGK", "length": 127 }, "evidence": [ { "id": "A0A4X1TZQ3", "url": "https://omabrowser.org/oma/group/A0A4X1TZQ3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZQ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZQ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZQ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZQ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3" } ], "pmid": "" }, { "name": "manchette assembly", "id": "GO:1905198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905198", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZQ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3" } ], "pmid": "" }, { "name": "sperm flagellum assembly", "id": "GO:0120316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120316", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1TZQ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TZQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U025-1", "uniprot_ac": "A0A4X1U025", "uniprot_id": "A0A4X1U025_PIG", "mass": { "chemical_mass": 36673.0, "monoisotopic_mass": 36673.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110259578", "type": "recommended", "evidence": [ { "id": "A0A4X1U025", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1U025", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U025", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U025", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259578", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025", "locus": {} } ], "crossref": [ { "id": "A0A4X1U025", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U025", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CIYMRPG", "url": "https://omabrowser.org/oma/group/CIYMRPG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1U025", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U025-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMILQISSLSVVTTENHMEKNDTETTNFILLGFFPEFRYITAIVYITLLIYMAAFTGNTLLILLIWLDSRLHTPMYFFLSQLSLMDLTLTSSIVPKMVANFFSGWRSISFLACGTQIFFSLTVAIAECILITLMCFDRYVAVCNPLRYPVIISPRVCLHMIVISWAGGAFTSFAHTAFTLHFHICSPREIPHFFCEVMAVLGIVCEDILAYEKAVVVTSILVLLLPLSLILSSYVLILLSLLQMNSPEVRNKALATCSSHLCVVSLYFGPGMCIYMRPGSAKTPRLNQGLFLFGTVLTPLLNPLAYSLRNKEVLSALKKLVGKCQSSR", "length": 328, "header": "tr|A0A4X1U025-1|A0A4X1U025_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259578 PE=3 SV=1 CANONICAL=A0A4X1U025-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U025-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025/entry#A0A4X1U025-1", "sequence": { "sequence": "MMILQISSLSVVTTENHMEKNDTETTNFILLGFFPEFRYITAIVYITLLIYMAAFTGNTLLILLIWLDSRLHTPMYFFLSQLSLMDLTLTSSIVPKMVANFFSGWRSISFLACGTQIFFSLTVAIAECILITLMCFDRYVAVCNPLRYPVIISPRVCLHMIVISWAGGAFTSFAHTAFTLHFHICSPREIPHFFCEVMAVLGIVCEDILAYEKAVVVTSILVLLLPLSLILSSYVLILLSLLQMNSPEVRNKALATCSSHLCVVSLYFGPGMCIYMRPGSAKTPRLNQGLFLFGTVLTPLLNPLAYSLRNKEVLSALKKLVGKCQSSR", "length": 328, "header": "tr|A0A4X1U025-1|A0A4X1U025_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259578 PE=3 SV=1 CANONICAL=A0A4X1U025-1" }, "locus": { "chromosome": "2", "start_pos": 52065182, "end_pos": 52064199, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015270.4", "url": "https://www.ensembl.org/id/ENSSSCT00000015270.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014864.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014864.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U025", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "G5E6M9-1", "protein_name": "Olfactory receptor", "gene_name": "OR2AV11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWGGNETESTNFILLGFFPEFRYTTALVSIVLLIYMAAFIGNTLLVLLIWLDSRLHTPMYFLLSQLSLMDLTLTSSIIPKMVANFFSGWQSISFLACGTQIFFSLTVAIGECILITVMCFDRYVAICNPLRYPVIMSPRMCWQVAAMSWAGGALTSSGHTAFTLHFHICSPREIPHFFCEVMAVLRIVCEDISAYEKAVVVTSILVLLLPLSLILSSYILIFLAVLRMNSPEGRNKTLATCSSHLCVVGLYFGPGMCIYMRPGSAKTPKLNQGLFLFGTVLTPLLNPLAYSLRNKEVLCSLKKLMGRFQSTR", "length": 312 }, "evidence": [ { "id": "A0A4X1U025", "url": "https://omabrowser.org/oma/group/A0A4X1U025/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U025", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U025", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U025", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U025", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U025", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U025" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 306, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 21, "end_pos": 23 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U0G3-1", "uniprot_ac": "A0A4X1U0G3", "uniprot_id": "A0A4X1U0G3_PIG", "mass": { "chemical_mass": 10130.0, "monoisotopic_mass": 10130.0 }, "refseq": { "ac": "XP_005667667", "name": "guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667667" }, "gene_names": [ { "name": "GNGT1", "type": "recommended", "evidence": [ { "id": "A0A4X1U0G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3" } ] }, { "name": "GNGT1", "type": "synonym", "evidence": [ { "id": "XP_005667667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667667" } ] } ], "protein_names": [ { "name": "Guanine nucleotide-binding protein subunit gamma", "type": "recommended", "evidence": [ { "id": "A0A4X1U0G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3/entry#names_and_taxonomy" } ] }, { "name": "guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005667667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667667" } ] } ], "function": [ { "annotation": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0G3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3#function" }, { "database": "UniProtKB", "id": "RU004973", "url": "https://www.uniprot.org/uniprotkb/RU004973#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0G3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GNGT1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3", "locus": { "chromosome": "9", "start_pos": 73719161, "end_pos": 73403740, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015323", "url": "https://www.ensembl.org/id/ENSSSCG00000015323" } ] } } ], "crossref": [ { "id": "A0A4X1U0G3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U0G3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00068", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00068", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519790", "url": "https://www.ncbi.nlm.nih.gov/gene/100519790", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519790", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519790", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR13809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1296041", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296041", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-202040", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202040", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-392170", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-392451", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392451", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-4086398", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4086398", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418597", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-428930", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-428930", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-456926", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-456926", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6814122", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6814122", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8964616", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-997272", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005667667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667667", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U0G3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U0G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKSCAKDNVSSRPKMPVINIEDLTEKDKLKMEVDQLKKEVTLERMLVSKCCEEVKDYVEERSGEDPLVKGIPEDKNPFKELKGGCVIS", "length": 89, "header": "tr|A0A4X1U0G3-1|A0A4X1U0G3_PIG Isoform 1 of Guanine nucleotide-binding protein subunit gamma OS=Sus scrofa OX=9823 GN=GNGT1 PE=1 SV=1 CANONICAL=A0A4X1U0G3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U0G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3/entry#A0A4X1U0G3-1", "sequence": { "sequence": "MEKSCAKDNVSSRPKMPVINIEDLTEKDKLKMEVDQLKKEVTLERMLVSKCCEEVKDYVEERSGEDPLVKGIPEDKNPFKELKGGCVIS", "length": 89, "header": "tr|A0A4X1U0G3-1|A0A4X1U0G3_PIG Isoform 1 of Guanine nucleotide-binding protein subunit gamma OS=Sus scrofa OX=9823 GN=GNGT1 PE=1 SV=1 CANONICAL=A0A4X1U0G3-1" }, "locus": { "chromosome": "9", "start_pos": 73715331, "end_pos": 73703848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016696.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016696.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016250.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016250.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0G3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519790", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519790", "resource": "KEGG Pathway" }, { "id": "R-SSC-1296041", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296041", "resource": "Reactome", "description": "Activation of G protein gated Potassium channels" }, { "id": "R-SSC-202040", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202040", "resource": "Reactome", "description": "G-protein activation" }, { "id": "R-SSC-392170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392170", "resource": "Reactome", "description": "ADP signalling through P2Y purinoceptor 12" }, { "id": "R-SSC-392451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-392451", "resource": "Reactome", "description": "G beta:gamma signalling through PI3Kgamma" }, { "id": "R-SSC-4086398", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4086398", "resource": "Reactome", "description": "Ca2+ pathway" }, { "id": "R-SSC-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-SSC-418597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418597", "resource": "Reactome", "description": "G alpha (z) signalling events" }, { "id": "R-SSC-428930", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-428930", "resource": "Reactome", "description": "Thromboxane signalling through TP receptor" }, { "id": "R-SSC-456926", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-456926", "resource": "Reactome", "description": "Thrombin signalling through proteinase activated receptors (PARs)" }, { "id": "R-SSC-6814122", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6814122", "resource": "Reactome", "description": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" }, { "id": "R-SSC-8964616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964616", "resource": "Reactome", "description": "G beta:gamma signalling through CDC42" }, { "id": "R-SSC-997272", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "resource": "Reactome", "description": "Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G-protein beta-subunit binding", "id": "GO:0031681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031681", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0G3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0G3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "heterotrimeric G-protein complex", "id": "GO:0005834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005834", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U0G3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U0G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U0G3" }, { "id": "PS50058", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50058" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G protein gamma", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 89, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U122-1", "uniprot_ac": "A0A4X1U122", "uniprot_id": "A0A4X1U122_PIG", "mass": { "chemical_mass": 34919.0, "monoisotopic_mass": 34919.0 }, "refseq": { "ac": "XP_013850056", "name": "olfactory receptor 2AK2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850056" }, "gene_names": [ { "name": "LOC102163216", "type": "recommended", "evidence": [ { "id": "A0A4X1U122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122" } ] }, { "name": "LOC102163216", "type": "synonym", "evidence": [ { "id": "XP_013850056", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850056" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1U122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2AK2-like", "type": "synonym", "evidence": [ { "id": "XP_013850056", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850056" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U122", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U122", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC102163216", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122", "locus": {} } ], "crossref": [ { "id": "A0A4X1U122", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U122", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "102163216", "url": "https://www.ncbi.nlm.nih.gov/gene/102163216", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:102163216", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102163216", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KICCLMV", "url": "https://omabrowser.org/oma/group/KICCLMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U122", "url": "https://www.orthodb.org/?gene=A0A4X1U122", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013850056", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850056", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U122", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U122-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGNQTFGTDFILLGLFQYGPMNSFLFVAIAMAFSVALMGNIILILLIRLDSRLHSPMYFLLSQLSFIDMMYISTTVPKMAINFLSSSKTITFLGCESQTFVFLALGGTEALLLGFMSYDRYVAICHPLHYPVLMSKKICWFMVTCGWTSCSINSLIHTVYVFQLPFCRSRLVNHFFCEVPSLLPLVCQDTSQYEYTILLSGLIILLLPFMAILASYACVLTVVFQMSSEKGRTKAISTCSSHLIVASLFYMTTLSTYTRPHSLHSPEEDKIVAVFYTIITPLLNPFIYSLRNKEVMGALRRLFVQKV", "length": 309, "header": "tr|A0A4X1U122-1|A0A4X1U122_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC102163216 PE=3 SV=1 CANONICAL=A0A4X1U122-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U122-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122/entry#A0A4X1U122-1", "sequence": { "sequence": "MEPGNQTFGTDFILLGLFQYGPMNSFLFVAIAMAFSVALMGNIILILLIRLDSRLHSPMYFLLSQLSFIDMMYISTTVPKMAINFLSSSKTITFLGCESQTFVFLALGGTEALLLGFMSYDRYVAICHPLHYPVLMSKKICWFMVTCGWTSCSINSLIHTVYVFQLPFCRSRLVNHFFCEVPSLLPLVCQDTSQYEYTILLSGLIILLLPFMAILASYACVLTVVFQMSSEKGRTKAISTCSSHLIVASLFYMTTLSTYTRPHSLHSPEEDKIVAVFYTIITPLLNPFIYSLRNKEVMGALRRLFVQKV", "length": 309, "header": "tr|A0A4X1U122-1|A0A4X1U122_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC102163216 PE=3 SV=1 CANONICAL=A0A4X1U122-1" }, "locus": { "chromosome": "2", "start_pos": 55750120, "end_pos": 55749194, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041998.2", "url": "https://www.ensembl.org/id/ENSSSCT00000041998.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031906.1", "url": "https://www.ensembl.org/id/ENSSSCP00000031906.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U122", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102163216", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102163216", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ACJ5-1", "protein_name": "Olfactory receptor", "gene_name": "Or2ak5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTGNHSCGTDFTLVGLFKYGHLDTILFTVIALLFAVALIGNITLVHLIRLDRTLHTPMYFLLSQLSIIDMMYISTTVPKMAANFLSDTKTISFLGCAIQTFVFLTLGGSEALLLGFMSYDRYIAICQPLHYPLLMSRNICCSMVAGAWSSSSINAFVHTVYVFQLPFCGSRIVNHFFCEVPSLLPLVCEDTSQYEHTVLLSGLVILLLPFLAILVSYARVLVVVFQMGSGKGQSRAVSTCSSHLTVASLFYVTGLCTYTQPHSLHSPGRDKVVAVLYSIVTPVLNPFIYSLRNKEVMGALRRQVG", "length": 306 }, "evidence": [ { "id": "A0A4X1U122", "url": "https://omabrowser.org/oma/group/A0A4X1U122/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BGJ3-1", "protein_name": "Olfactory receptor", "gene_name": "OR2AK3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKTGNQSVKTDFILLGLFQYGPMDTVLFAVIAILFSVALMGNIILILLIQLDTRLHTPMYFLLSQLSFIDMMYISTTVPKMATNFLSNSKTITFLGCEIQAFVFLVLGGTEALLLGFMSYDRYVAIYHPLRYPVLMSKKICWFMITCAWTSCSINSLIHTLYAFQLPFCRSRLINHFFCEIPSMLPLVCQDTSQYEHTILLSGLIILLLPFMAILASYACVLTVVFQMSSGKGQTKAISTCSSHLTVASLFYVTTLSTYTRPHSLHSLEEDKIIAVFYTIITPLLNPFIYSLRNKEVIRALRRVCVQKI", "length": 309 }, "evidence": [ { "id": "A0A4X1U122", "url": "https://omabrowser.org/oma/group/A0A4X1U122/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5NCD7-1", "protein_name": "Olfactory receptor", "gene_name": "Or2ak5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESGNHSCGTEFTLVGLFQYGHMDTFLFTLIAILFAVALMGNITLVLLIRLDRRLHTPMYFFLSQLSIIDMMYISTTVPKMAANFLSDTKAISFLGCAVQTFVFLTLGGSEALLLGFMSYDRYIAICQPLHYPVLMSRKICCSMVAGAWSSSSINAFMHTVYVFQLPFCGSRMVNHFFCEVPSLLPLVCEDTSQYEHTVLVSGLVILLLPFLAILASYARVLVVVIQMGSGKGQSRAVSTCSSHLTVASLFYVTTLSTYTQPHSLHSPGRDKVVAVLYSIVTPVLNPFIYSLRNKEVMGALRRQRG", "length": 306 }, "evidence": [ { "id": "A0A4X1U122", "url": "https://omabrowser.org/oma/group/A0A4X1U122/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NG84-1", "protein_name": "Olfactory receptor 2AK2", "gene_name": "OR2AK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNISDVISFDILVSAMKTGNQSFGTDFLLVGLFQYGWINSLLFVVIATLFTVALTGNIMLIHLIRLNTRLHTPMYFLLSQLSIVDLMYISTTVPKMAVSFLSQSKTIRFLGCEIQTYVFLALGGTEALLLGFMSYDRYVAICHPLHYPMLMSKKICCLMVACAWASGSINAFIHTLYVFQLPFCRSRLINHFFCEVPALLSLVCQDTSQYEYTVLLSGLIILLLPFLAILASYARVLIVVFQMSSGKGQAKAVSTCSSHLIVASLFYATTLFTYTRPHSLRSPSRDKAVAVFYTIVTPLLNPFIYSLRNKEVTGAVRRLLGYWICCRKYDFRSLY", "length": 335 }, "evidence": [ { "id": "A0A4X1U122", "url": "https://omabrowser.org/oma/group/A0A4X1U122/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U122", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U122", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U122", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U122", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U122" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U132-1", "uniprot_ac": "A0A4X1U132", "uniprot_id": "A0A4X1U132_PIG", "mass": { "chemical_mass": 34236.0, "monoisotopic_mass": 34236.0 }, "refseq": { "ac": "XP_013850057", "name": "olfactory receptor 2W3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850057" }, "gene_names": [ { "name": "LOC100624683", "type": "recommended", "evidence": [ { "id": "A0A4X1U132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132" } ] }, { "name": "LOC100624683", "type": "synonym", "evidence": [ { "id": "XP_013850057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850057" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1U132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2W3", "type": "synonym", "evidence": [ { "id": "XP_013850057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850057" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U132", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U132", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100624683", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132", "locus": {} } ], "crossref": [ { "id": "A0A4X1U132", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U132", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15434", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15434", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100624683", "url": "https://www.ncbi.nlm.nih.gov/gene/100624683", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624683", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624683", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGHRSVD", "url": "https://omabrowser.org/oma/group/CGHRSVD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U132", "url": "https://www.orthodb.org/?gene=A0A4X1U132", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013850057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850057", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U132", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U132-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGTNESTQENFVLLGFSDRPHLERILFVVILIAYLLTLVGNTTIILVSRLDPHLHTPMYFFLAHLSFLDLSFTTSSIPQLLYNLNGHDKTISYTGCAIQLFLFLGLGGVECLLLAVMAYDRFVAVCKPLHYTVIMNPRLCLGLVLVAWGCGVANSLAMSPVTLLLPRCGRRSVDHFLCEMPALIRMACVNTAAIEGTVFVLAVGIVLSPLVFILGSYGYIVRAVLLIESASGRQKVFNTCGSHLTVVSLFYGNIIYMYMQPGNSSSQDQGKFLTLFYNIVTPLLNPLIYTLRNKEVKGALRRLLLCNR", "length": 309, "header": "tr|A0A4X1U132-1|A0A4X1U132_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100624683 PE=3 SV=1 CANONICAL=A0A4X1U132-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U132-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132/entry#A0A4X1U132-1", "sequence": { "sequence": "MDGTNESTQENFVLLGFSDRPHLERILFVVILIAYLLTLVGNTTIILVSRLDPHLHTPMYFFLAHLSFLDLSFTTSSIPQLLYNLNGHDKTISYTGCAIQLFLFLGLGGVECLLLAVMAYDRFVAVCKPLHYTVIMNPRLCLGLVLVAWGCGVANSLAMSPVTLLLPRCGRRSVDHFLCEMPALIRMACVNTAAIEGTVFVLAVGIVLSPLVFILGSYGYIVRAVLLIESASGRQKVFNTCGSHLTVVSLFYGNIIYMYMQPGNSSSQDQGKFLTLFYNIVTPLLNPLIYTLRNKEVKGALRRLLLCNR", "length": 309, "header": "tr|A0A4X1U132-1|A0A4X1U132_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100624683 PE=3 SV=1 CANONICAL=A0A4X1U132-1" }, "locus": { "chromosome": "2", "start_pos": 55810972, "end_pos": 55810046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024308.3", "url": "https://www.ensembl.org/id/ENSSSCT00000024308.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026640.2", "url": "https://www.ensembl.org/id/ENSSSCP00000026640.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U132", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624683", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624683", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BNP4-1", "protein_name": "Olfactory receptor", "gene_name": "OR2W3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDGTNESNQGNFILLGFSDRPHLERILFVVILIAYLLILVGNTTIILVSWLDPHLHTPMYFFLAHLSFLDLSFTTSSIPQLLYNLSGSDKTISYTGCAIQLFLFLGLGGVECLLLAVMAYDRFVAVCKPLHYMVIMNPRLCLGLVLIAWGCGVANSLAMSPVTLRLPCCGRHSVDHFLCEMPALIRMACVNTAAIEGTVFVLAVGIVLSPLVFILVSYGYIVRAVLQIQSASGRQKAFNTCGSHLTVVSLFYGNIIYMYMQPGNSSSQDQGKFLTLFYNIVTPLLNPLIYTLRNKEVKGALRRLLLHDREKKREKVFLEPF", "length": 321 }, "evidence": [ { "id": "A0A4X1U132", "url": "https://omabrowser.org/oma/group/A0A4X1U132/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7Z3T1-1", "protein_name": "Olfactory receptor 2W3", "gene_name": "OR2W3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGTNGSTQTHFILLGFSDRPHLERILFVVILIAYLLTLVGNTTIILVSRLDPHLHTPMYFFLAHLSFLDLSFTTSSIPQLLYNLNGCDKTISYMGCAIQLFLFLGLGGVECLLLAVMAYDRCVAICKPLHYMVIMNPRLCRGLVSVTWGCGVANSLAMSPVTLRLPRCGHHEVDHFLREMPALIRMACVSTVAIEGTVFVLAVGVVLSPLVFILLSYSYIVRAVLQIRSASGRQKAFGTCGSHLTVVSLFYGNIIYMYMQPGASSSQDQGMFLMLFYNIVTPLLNPLIYTLRNREVKGALGRLLLGKRELGKE", "length": 314 }, "evidence": [ { "id": "A0A4X1U132", "url": "https://omabrowser.org/oma/group/A0A4X1U132/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U132", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U132", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U132", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U132", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U132" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 264, "end_pos": 266 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U194-1", "uniprot_ac": "A0A4X1U194", "uniprot_id": "A0A4X1U194_PIG", "mass": { "chemical_mass": 28555.0, "monoisotopic_mass": 28555.0 }, "refseq": { "ac": "XP_003131835", "name": "Golgi SNAP receptor complex member 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131835" }, "gene_names": [ { "name": "GOSR1", "type": "recommended", "evidence": [ { "id": "A0A4X1U194", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194" } ] }, { "name": "GOSR1", "type": "synonym", "evidence": [ { "id": "XP_003131835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131835" } ] } ], "protein_names": [ { "name": "Golgi SNAP receptor complex member 1", "type": "recommended", "evidence": [ { "id": "A0A4X1U194", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194/entry#names_and_taxonomy" } ] }, { "name": "Golgi SNAP receptor complex member 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003131835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131835" } ] } ], "function": [ { "annotation": "Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0P7S9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0P7S9#function" }, { "database": "UniProtKB", "id": "ARBA00025091", "url": "https://www.uniprot.org/uniprotkb/ARBA00025091#function" }, { "database": "UniProtKB", "id": "A0A8D0P3W6", "url": "https://www.uniprot.org/uniprotkb/A0A8D0P3W6#function" }, { "database": "UniProtKB", "id": "A0A5G2QUU8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUU8#function" }, { "database": "UniProtKB", "id": "A0A4X1U194", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194#function" }, { "database": "UniProtKB", "id": "A0A5G2QM89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM89#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U194", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GOSR1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194", "locus": { "chromosome": "12", "start_pos": 46597071, "end_pos": 46541229, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000029262", "url": "https://www.ensembl.org/id/ENSSSCG00000029262" } ] } } ], "crossref": [ { "id": "A0A4X1U194", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U194", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000029262", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000029262", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15864", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15864", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100517676", "url": "https://www.ncbi.nlm.nih.gov/gene/100517676", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517676", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517676", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QAYAVND", "url": "https://omabrowser.org/oma/group/QAYAVND/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U194", "url": "https://www.orthodb.org/?gene=A0A4X1U194", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8D0P3W6", "url": "https://www.orthodb.org/?gene=A0A8D0P3W6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21094", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21094", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21094:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21094:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131835", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131835", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U194", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U194-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QM89", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QM89-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUU8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0P3W6", "url": "https://www.uniprot.org/uniprotkb/A0A8D0P3W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0P3W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0P3W6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0P7S9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0P7S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0P7S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0P7S9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFVAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIQSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVVGICTILLLLYAFH", "length": 250, "header": "tr|A0A4X1U194-1|A0A4X1U194_PIG Isoform 1 of Golgi SNAP receptor complex member 1 OS=Sus scrofa OX=9823 GN=GOSR1 PE=3 SV=1 CANONICAL=A0A4X1U194-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U194-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194/entry#A0A4X1U194-1", "sequence": { "sequence": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFVAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIQSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVVGICTILLLLYAFH", "length": 250, "header": "tr|A0A4X1U194-1|A0A4X1U194_PIG Isoform 1 of Golgi SNAP receptor complex member 1 OS=Sus scrofa OX=9823 GN=GOSR1 PE=3 SV=1 CANONICAL=A0A4X1U194-1" }, "locus": { "chromosome": "12", "start_pos": 46593125, "end_pos": 46541250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043406.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043406.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031951.1", "url": "https://www.ensembl.org/id/ENSSSCP00000031951.1" } ] } }, { "isoform_ac": "A0A5G2QM89-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194/entry#A0A5G2QM89-1", "sequence": { "sequence": "MFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFVAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIQSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVVGICTILLLLYAFH", "length": 185, "header": "tr|A0A5G2QM89-1|A0A5G2QM89_PIG Computationally mapped isoform of Golgi SNAP receptor complex member 1 OS=Sus scrofa OX=9823 GN=GOSR1 PE=3 SV=1 CANONICAL=A0A4X1U194-1" }, "locus": { "chromosome": "12", "start_pos": 46593125, "end_pos": 46553323, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075594.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075594.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065150.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065150.1" } ] } }, { "isoform_ac": "A0A5G2QUU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194/entry#A0A5G2QUU8-1", "sequence": { "sequence": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFVAIRERENLMGSVRKDIDGSGVNNRRTELFLKEHDHLRNIAMATKENMTSQRGMLKSIQSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVVGICTILLLLYAFH", "length": 236, "header": "tr|A0A5G2QUU8-1|A0A4X1U194_PIG Computationally mapped isoform of Golgi SNAP receptor complex member 1 OS=Sus scrofa OX=9823 GN=GOSR1 PE=3 SV=2 CANONICAL=A0A4X1U194-1" }, "locus": { "chromosome": "12", "start_pos": 46593125, "end_pos": 46541250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078314.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078314.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067919.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067919.2" } ] } }, { "isoform_ac": "A0A8D0P3W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194/entry#A0A8D0P3W6-1", "sequence": { "sequence": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFVAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIQSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVVGICTILLLLYAFH", "length": 248, "header": "tr|A0A8D0P3W6-1|A0A4X1U194_PIG Computationally mapped isoform of Golgi SNAP receptor complex member 1 OS=Sus scrofa OX=9823 GN=GOSR1 PE=3 SV=1 CANONICAL=A0A4X1U194-1" }, "locus": { "chromosome": "12", "start_pos": 46593125, "end_pos": 46541250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030283.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030283.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020047.3", "url": "https://www.ensembl.org/id/ENSSSCP00000020047.3" } ] } }, { "isoform_ac": "A0A8D0P7S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194/entry#A0A8D0P7S9-1", "sequence": { "sequence": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGRRDSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFVAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNKHTYSFIYFYSKHIMVFSIVTVLSVLINLILLMILFNRNKIATLVTMIRKNMMLSVYKMCIHITCFLYYVFYCLNVCFL", "length": 249, "header": "tr|A0A8D0P7S9-1|A0A4X1U194_PIG Computationally mapped isoform of Golgi SNAP receptor complex member 1 OS=Sus scrofa OX=9823 GN=GOSR1 PE=3 SV=1 CANONICAL=A0A4X1U194-1" }, "locus": { "chromosome": "12", "start_pos": 46561237, "end_pos": 46541250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073187.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073187.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060035.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060035.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0P3W6", "url": "https://www.uniprot.org/uniprotkb/A0A8D0P3W6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517676", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517676", "resource": "KEGG Pathway" }, { "id": "R-SSC-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-SSC-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "E9QFW9-1", "protein_name": "Golgi SNAP receptor complex member 1", "gene_name": "gosr1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGGNSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSSSRDGRRGDSSSDTTPLLCNSTQDRMFETMSVEIEQLLAKLTGVNDKMAEYTSTPGVTSLNAALMHTLQRHRDILQDYTHEFHKTKSNFMAIREREDLLGSVRKDIETYKSGSGVNNRRTELFLKEHEHLRNSDRLIDDTISIAMATKENMTSQRGLLKSIQSRVNTLANRFPAINNLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "length": 248 }, "evidence": [ { "id": "A0A4X1U194", "url": "https://omabrowser.org/oma/group/A0A4X1U194/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O22151-2", "protein_name": "Golgi SNAP receptor complex member 1-2", "gene_name": "GOS12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTESSLDLQESGWEELRREARKIEGDLDVKLSSYAKLGARFTQGDTDLVMNYEKVLKCVLVSGYVDTGSPTVGSGRSWKSMEMEIQSLLEKLLDINDSMSRCAASAAPTTSVTQKLARHRDILHEYTQEFRRIKGNINSLREHAELLSSVRDDISEYKASGSMSPGVQVLRERASIHGSISHIDDVIGQAQATRAVLGSQRSLFSDVQGKVKNLGDKFPVIRGLLGSIKRKRSRDTLILSAVIAACTLFLIIYWLSK", "length": 257 }, "evidence": [ { "id": "A0A4X1U194", "url": "https://omabrowser.org/oma/group/A0A4X1U194/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O88630-1", "protein_name": "Golgi SNAP receptor complex member 1", "gene_name": "Gosr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSGSRDGGRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFTAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "length": 250 }, "evidence": [ { "id": "A0A4X1U194", "url": "https://omabrowser.org/oma/group/A0A4X1U194/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O95249-1", "protein_name": "Golgi SNAP receptor complex member 1", "gene_name": "GOSR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGTSSYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSTRDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "length": 250 }, "evidence": [ { "id": "A0A4X1U194", "url": "https://omabrowser.org/oma/group/A0A4X1U194/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P38736-1", "protein_name": "Golgi SNAP receptor complex member 1", "gene_name": "GOS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSQPSFVTIRGKAISLETQTESLLSKYSTFAQTTSSEQTGQEKKIDKQLEGILGQRQDVIDSLTQICDSNPAISASKLSQLHRHKEILQDHWKSFRNIRSSIQQERNRLNLLFSVKNDIANSTTDAPAPIGDADEYIQNETRRIDQSNNVVDRLISQAWETRSQFHSQSNVLNTANNKVLQTLQRIPGVNQLIMKINTRRKKNAFVLATITTLCILFLFFTW", "length": 223 }, "evidence": [ { "id": "A0A4X1U194", "url": "https://omabrowser.org/oma/group/A0A4X1U194/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2TBU3-1", "protein_name": "Golgi SNAP receptor complex member 1", "gene_name": "GOSR1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGRRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGINDKMAEYTSSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFVAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIQSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGVCTILLLLYAFH", "length": 250 }, "evidence": [ { "id": "A0A4X1U194", "url": "https://omabrowser.org/oma/group/A0A4X1U194/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q62931-1", "protein_name": "Golgi SNAP receptor complex member 1", "gene_name": "Gosr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGGRDRYSSDTTPLLNGSSQDRMFETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFMAIRERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGMLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH", "length": 250 }, "evidence": [ { "id": "A0A4X1U194", "url": "https://omabrowser.org/oma/group/A0A4X1U194/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U194", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194" } ], "pmid": "" }, { "name": "Golgi medial cisterna", "id": "GO:0005797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005797", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U194", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U194", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U194", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U194", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U194", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U194", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194" } ], "pmid": "" }, { "name": "inter-Golgi cisterna vesicle-mediated transport", "id": "GO:0048219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048219", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U194", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U194", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U194" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U1G1-1", "uniprot_ac": "A0A4X1U1G1", "uniprot_id": "A0A4X1U1G1_PIG", "mass": { "chemical_mass": 22913.0, "monoisotopic_mass": 22913.0 }, "refseq": { "ac": "XP_020931690", "name": "ubiquitin-conjugating enzyme E2 E3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931690" }, "gene_names": [ { "name": "UBE2E3", "type": "recommended", "evidence": [ { "id": "A0A4X1U1G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1" } ] }, { "name": "UBE2E3", "type": "synonym", "evidence": [ { "id": "XP_020931690", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931690" } ] } ], "protein_names": [ { "name": "E2 ubiquitin-conjugating enzyme", "type": "recommended", "evidence": [ { "id": "A0A4X1U1G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.23", "type": "synonym", "evidence": [ { "id": "A0A4X1U1G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-conjugating enzyme E2 E3", "type": "synonym", "evidence": [ { "id": "XP_020931690", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931690" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1G1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UBE2E3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1", "locus": { "chromosome": "15", "start_pos": 86561911, "end_pos": 86471156, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000033987", "url": "https://www.ensembl.org/id/ENSSSCG00000033987" } ] } } ], "crossref": [ { "id": "A0A4X1U1G1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U1G1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100520938", "url": "https://www.ncbi.nlm.nih.gov/gene/100520938", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520938", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520938", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GDRAKHD", "url": "https://omabrowser.org/oma/group/GDRAKHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U1G1", "url": "https://www.orthodb.org/?gene=A0A4X1U1G1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24068", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24068", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8866652", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8866652", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020931690", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931690", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U1G1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U1G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERKPSATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "length": 207, "header": "tr|A0A4X1U1G1-1|A0A4X1U1G1_PIG Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Sus scrofa OX=9823 GN=UBE2E3 PE=3 SV=1 CANONICAL=A0A4X1U1G1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U1G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1/entry#A0A4X1U1G1-1", "sequence": { "sequence": "MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERKPSATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "length": 207, "header": "tr|A0A4X1U1G1-1|A0A4X1U1G1_PIG Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Sus scrofa OX=9823 GN=UBE2E3 PE=3 SV=1 CANONICAL=A0A4X1U1G1-1" }, "locus": { "chromosome": "15", "start_pos": 86561755, "end_pos": 86472552, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064702.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064702.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056424.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056424.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1G1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520938", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520938", "resource": "KEGG Pathway" }, { "id": "R-SSC-8866652", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8866652", "resource": "Reactome", "description": "Synthesis of active ubiquitin: roles of E1 and E2 enzymes" }, { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HDP9-1", "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "Ube2e3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERKPSATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "length": 207 }, "evidence": [ { "id": "A0A4X1U1G1", "url": "https://omabrowser.org/oma/group/A0A4X1U1G1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P52483-1", "protein_name": "Ubiquitin-conjugating enzyme E2 E3", "gene_name": "Ube2e3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERKPSATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "length": 207 }, "evidence": [ { "id": "A0A4X1U1G1", "url": "https://omabrowser.org/oma/group/A0A4X1U1G1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P52485-1", "protein_name": "Ubiquitin-conjugating enzyme E2-24 kDa", "gene_name": "Ubc2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSTPAAGSAAEVATSSATSNAPSAPSTTASNVSNTSQPTTAGTPQARGGRGSNANGGASGSNAGGGDEPRKEAKTTPRISRALGTSAKRIQKELAEITLDPPPNCSAGPKGDNLYEWVSTILGPPGSVYEGGVFFLDIHFSPEYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLQNREEHDRIARLWTKRYAT", "length": 232 }, "evidence": [ { "id": "A0A4X1U1G1", "url": "https://omabrowser.org/oma/group/A0A4X1U1G1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2T9X7-1", "protein_name": "Ubiquitin-conjugating enzyme E2 E3", "gene_name": "UBE2E3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERKPSATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "length": 207 }, "evidence": [ { "id": "A0A4X1U1G1", "url": "https://omabrowser.org/oma/group/A0A4X1U1G1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54TE1-1", "protein_name": "UBC core domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGDNRATKRIQKELADITTDPPSNCTAGVMGDNLYEWISTIIGPDDSPYEGGIFMLHIVFPVDYPFKPPKWRRIQFKTRIYHCNINSNGDICLDILKNNWSPALNIGKVLLSISSLLTDPNPNDPLVSTIAEQLLNDRVAHDNKAKEWTIRFAK", "length": 154 }, "evidence": [ { "id": "A0A4X1U1G1", "url": "https://omabrowser.org/oma/group/A0A4X1U1G1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9LJD7-1", "protein_name": "Constitutive photomorphogenesis protein 10", "gene_name": "COP10", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMTPGGSGRLRPLPTAMYAGYSGTASSWVAKTSVSASGKRIQREMAELNIDPPPDCSAGPKGDNLYHWIATIIGPSGTPYEGGIFFLDIIFPSDYPFKPPKLVFKTRIYHCNVDTAGDLSVNILRDSWSPALTITKVLQAIRSIFLKPEPYSPALPVIARLYLTDREKHDEVAKEWTLRFAK", "length": 182 }, "evidence": [ { "id": "A0A4X1U1G1", "url": "https://omabrowser.org/oma/group/A0A4X1U1G1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1G1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1G1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1G1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1G1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1G1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1G1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1G1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-8852127", "name": "UBA6 conjugates ubiquitin to cytosolic E2 enzymes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8852127", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8852127" } ] }, { "id": "R-SSC-8852129", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8852129", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8852129" } ] }, { "id": "R-SSC-8852130", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8852130", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8852130" } ] }, { "id": "R-SSC-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983140" } ] }, { "id": "R-SSC-983152", "name": "Transfer of ubiquitin from E1 to E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983152", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983152" } ] }, { "id": "R-SSC-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983156" } ] }, { "id": "R-SSC-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U1G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1G1" }, { "id": "PS50127", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50127" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 207, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U1L0-1", "uniprot_ac": "A0A4X1U1L0", "uniprot_id": "A0A4X1U1L0_PIG", "mass": { "chemical_mass": 17936.0, "monoisotopic_mass": 17936.0 }, "refseq": { "ac": "XP_020926594", "name": "transmembrane protein 50B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926594" }, "gene_names": [ { "name": "TMEM50B", "type": "recommended", "evidence": [ { "id": "A0A4X1U1L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1L0" } ] }, { "name": "TMEM50B", "type": "synonym", "evidence": [ { "id": "XP_020926594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926594" } ] } ], "protein_names": [ { "name": "Transmembrane protein 50B", "type": "synonym", "evidence": [ { "id": "A0A4X1U1L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1L0/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 50B", "type": "synonym", "evidence": [ { "id": "XP_020926594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926594" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1L0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1L0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMEM50B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1L0", "locus": { "chromosome": "13", "start_pos": 197046682, "end_pos": 197093241, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000034624", "url": "https://www.ensembl.org/id/ENSSSCG00000034624" } ] } } ], "crossref": [ { "id": "100532728", "url": "https://www.ncbi.nlm.nih.gov/gene/100532728", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100532728", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100532728", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LWIMFAD", "url": "https://omabrowser.org/oma/group/LWIMFAD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U1L0", "url": "https://www.orthodb.org/?gene=A0A4X1U1L0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13180", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13180", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05255", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05255", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020926594", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926594", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U1L0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U1L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1L0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1E5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1E5Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1E5Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1E5Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGFLDNFRWPECECIDWSERRNAVASVVAGILFFTGWWIMIDAAVVYPKPEQLNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYESGCLGRTGARVWLFIGFMLMFGSLIASMWILFGAYVTQNTDVYPGLAVFFQNALIFFSTLIYKFGRTEELWT", "length": 158, "header": "tr|A0A4X1U1L0-1|A0A4X1U1L0_PIG Isoform 1 of Transmembrane protein 50B OS=Sus scrofa OX=9823 GN=TMEM50B PE=3 SV=1 CANONICAL=A0A4X1U1L0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U1L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1L0/entry#A0A4X1U1L0-1", "sequence": { "sequence": "MAGFLDNFRWPECECIDWSERRNAVASVVAGILFFTGWWIMIDAAVVYPKPEQLNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYESGCLGRTGARVWLFIGFMLMFGSLIASMWILFGAYVTQNTDVYPGLAVFFQNALIFFSTLIYKFGRTEELWT", "length": 158, "header": "tr|A0A4X1U1L0-1|A0A4X1U1L0_PIG Isoform 1 of Transmembrane protein 50B OS=Sus scrofa OX=9823 GN=TMEM50B PE=3 SV=1 CANONICAL=A0A4X1U1L0-1" }, "locus": { "chromosome": "13", "start_pos": 197067534, "end_pos": 197049699, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044403.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044403.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053017.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053017.1" } ] } }, { "isoform_ac": "A0A8D1E5Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1L0/entry#A0A8D1E5Q0-1", "sequence": { "sequence": "MAGFLDNFRWPECECIDWSERRNAVASVVAGILFFTGWWIMIDAAVVYPKPEQLNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYESGCLGRTGARVWLFIGFMLMFGSLIASMWILFGAYVTQTP", "length": 126, "header": "tr|A0A8D1E5Q0-1|A0A4X1U1L0_PIG Computationally mapped isoform of Transmembrane protein 50B OS=Sus scrofa OX=9823 GN=TMEM50B PE=3 SV=1 CANONICAL=A0A4X1U1L0-1" }, "locus": { "chromosome": "13", "start_pos": 197067534, "end_pos": 197049737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039442.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039442.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040618.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040618.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1E5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1E5Q0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100532728", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100532728", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I5Y6-1", "protein_name": "Transmembrane protein 50B isoform X1", "gene_name": "Tmem50b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGFLDNFRWPECECIDWSERRNAVASVVAGILFFTGWWIMIDAAVVYPKPEQLNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYESGCLGRTGARVWLFIGFMLMFGSLIASMWILFGAYVTQNIDVYPGLAVFFQNALIFFSTLIYKFGRTEELWT", "length": 158 }, "evidence": [ { "id": "A0A4X1U1L0", "url": "https://omabrowser.org/oma/group/A0A4X1U1L0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A1L1RX69-1", "protein_name": "Transmembrane protein 50B", "gene_name": "TMEM50B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGFLDNFRWPECECIDWSERRNAIASIVAGVLFFTGWWIMIDAAVVYPKPEQMNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYSDGCLGRTGARVWLFIGFMLMFGSLIASMWILFGAYVTQNTNVYPGLAVFFQNALIFFSTLIYKFGRTEELWG", "length": 158 }, "evidence": [ { "id": "A0A4X1U1L0", "url": "https://omabrowser.org/oma/group/A0A4X1U1L0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P56557-1", "protein_name": "Transmembrane protein 50B", "gene_name": "TMEM50B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGFLDNFRWPECECIDWSERRNAVASVVAGILFFTGWWIMIDAAVVYPKPEQLNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYESGCLGRTGARVWLFIGFMLMFGSLIASMWILFGAYVTQNTDVYPGLAVFFQNALIFFSTLIYKFGRTEELWT", "length": 158 }, "evidence": [ { "id": "A0A4X1U1L0", "url": "https://omabrowser.org/oma/group/A0A4X1U1L0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3SZL9-1", "protein_name": "Transmembrane protein 50B", "gene_name": "TMEM50B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGFLDNFRWPECECIDWSERRNAVASVVAGILFFTGWWIMIDAAVVYPKPEQLNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYESGCLGRTGARVWLFIGFMLMFGSLIASMWILFGAYVTQNTDVYPGLAVFFQNALIFFSTLIYKFGRTEELWT", "length": 158 }, "evidence": [ { "id": "A0A4X1U1L0", "url": "https://omabrowser.org/oma/group/A0A4X1U1L0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D1X9-1", "protein_name": "Transmembrane protein 50B", "gene_name": "Tmem50b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGFLDNFRWPECECIDWSERRNTVASVVAGILFFTGWWIMIDAAVVYPKPEQLNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYESGCLGRTGARVWLFIGFMLMFGSLIASMWILFGAYVTQNIDVYPGLAVFFQNALIFFSTLIYKFGRTEELWA", "length": 158 }, "evidence": [ { "id": "A0A4X1U1L0", "url": "https://omabrowser.org/oma/group/A0A4X1U1L0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1L0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1L0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1L0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1L0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U1L0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U1L0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U2I9-1", "uniprot_ac": "A0A4X1U2I9", "uniprot_id": "A0A4X1U2I9_PIG", "mass": { "chemical_mass": 28150.0, "monoisotopic_mass": 28150.0 }, "refseq": { "ac": "XP_005653583", "name": "peroxisomal membrane protein 11A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653583" }, "gene_names": [ { "name": "PEX11A", "type": "recommended", "evidence": [ { "id": "A0A4X1U2I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9" } ] }, { "name": "PEX11A", "type": "synonym", "evidence": [ { "id": "XP_005653583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653583" } ] } ], "protein_names": [ { "name": "Peroxisomal biosis factor 11 alpha", "type": "synonym", "evidence": [ { "id": "A0A4X1U2I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9/entry#names_and_taxonomy" } ] }, { "name": "peroxisomal membrane protein 11A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005653583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653583" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U2I9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PEX11A", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9", "locus": { "chromosome": "7", "start_pos": 55256220, "end_pos": 55264247, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027052", "url": "https://www.ensembl.org/id/ENSSSCG00000027052" } ] } } ], "crossref": [ { "id": "A0A4X1U2I9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U2I9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000027052", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027052", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100157485", "url": "https://www.ncbi.nlm.nih.gov/gene/100157485", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157485", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157485", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AKRTMQL", "url": "https://omabrowser.org/oma/group/AKRTMQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U2I9", "url": "https://www.orthodb.org/?gene=A0A4X1U2I9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12652", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12652", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12652:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12652:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005653583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653583", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U2I9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U2I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U2K2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U2K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QCU8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QCU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCU8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAFIRFTNQTQGRDRLFRATQYTCMLLRYLLEPKADKEKVVMKLKKLEASVSTGRKWFRVGNVVHALQATRESIHATDLVPRFCLTLASLNRVGYFICDTILFVKSIGITSGINKETWQVWAARYYCSSLLLSLVRDLYEISLQMEQVAHDRAKREKSPTQDPFGYSVADEETEWLQSFLLLLFRSLKKHPPLLLDTVKNFCDILNPLDQLGIYKSNAGIIGLGGLVSSLAGIITLAYPQMKLKIH", "length": 247, "header": "tr|A0A4X1U2I9-1|A0A4X1U2I9_PIG Isoform 1 of Peroxisomal biosis factor 11 alpha OS=Sus scrofa OX=9823 GN=PEX11A PE=4 SV=1 CANONICAL=A0A4X1U2I9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U2I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9/entry#A0A4X1U2I9-1", "sequence": { "sequence": "MDAFIRFTNQTQGRDRLFRATQYTCMLLRYLLEPKADKEKVVMKLKKLEASVSTGRKWFRVGNVVHALQATRESIHATDLVPRFCLTLASLNRVGYFICDTILFVKSIGITSGINKETWQVWAARYYCSSLLLSLVRDLYEISLQMEQVAHDRAKREKSPTQDPFGYSVADEETEWLQSFLLLLFRSLKKHPPLLLDTVKNFCDILNPLDQLGIYKSNAGIIGLGGLVSSLAGIITLAYPQMKLKIH", "length": 247, "header": "tr|A0A4X1U2I9-1|A0A4X1U2I9_PIG Isoform 1 of Peroxisomal biosis factor 11 alpha OS=Sus scrofa OX=9823 GN=PEX11A PE=4 SV=1 CANONICAL=A0A4X1U2I9-1" }, "locus": { "chromosome": "7", "start_pos": 55264081, "end_pos": 55258080, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022362.4", "url": "https://www.ensembl.org/id/ENSSSCT00000022362.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021455.1", "url": "https://www.ensembl.org/id/ENSSSCP00000021455.1" } ] } }, { "isoform_ac": "A0A4X1U2K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9/entry#A0A4X1U2K2-1", "sequence": { "sequence": "MDAFIRFTNQTQGRDRLFRATQYTCMLLRYLLEPKADKEKVVMKLKKLEASVSTGRKYRMSSYLC", "length": 65, "header": "tr|A0A4X1U2K2-1|A0A4X1U2K2_PIG Computationally mapped isoform of Peroxisomal biosis factor 11 alpha OS=Sus scrofa OX=9823 GN=PEX11A PE=4 SV=1 CANONICAL=A0A4X1U2I9-1" }, "locus": { "chromosome": "7", "start_pos": 55264081, "end_pos": 55256220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092732.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092732.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078182.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078182.1" } ] } }, { "isoform_ac": "A0A5G2QCU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9/entry#A0A5G2QCU8-1", "sequence": { "sequence": "MDAFIRFTNQTQGRDRLFRVQSRQCGACSTGDSREHSCH", "length": 39, "header": "tr|A0A5G2QCU8-1|A0A4X1U2I9_PIG Computationally mapped isoform of Peroxisomal biosis factor 11 alpha OS=Sus scrofa OX=9823 GN=PEX11A PE=4 SV=1 CANONICAL=A0A4X1U2I9-1" }, "locus": { "chromosome": "7", "start_pos": 55264081, "end_pos": 55258588, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068015.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068015.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061401.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061401.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QCU8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCU8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157485", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157485", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HX37-1", "protein_name": "Peroxisomal membrane protein 11A isoform X1", "gene_name": "Pex11a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDAFVRFANQSQGRDRLFRATQHACMLLRYLLESKAGKEAVVMKLKSLESSVSTGRKWFRLGNVVHAIQATEQSIQVTDLVPRLCLTLANLNRVVYYICDTVLWVKSVGLTSGVNREKWQMWATRHYYYFLLMSLVRDLYEILLQMERVASDRAKRERSSQGSPGYSVVHEDTDWLQSFLRLLFHSLRQHPPLLLDTVKNFCDILIPLNQLGIYKSNLGVVGLGGLVSSVAGLITVMYPQLKLKTR", "length": 246 }, "evidence": [ { "id": "A0A4X1U2I9", "url": "https://omabrowser.org/oma/group/A0A4X1U2I9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0ZCB5-1", "protein_name": "Peroxisomal biosis factor 11 alpha", "gene_name": "PEX11A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPRGPLSPRGVPGRTLLAVTPPAPAPLCTGCHGNGALRRRPAGNALVSGGFRRETGRGGAAAHLPGCPAATAMQGFVDFTNRSQGRERIFRATQYTCMLLSYVIERKADNEKLVLKLKQLESSMSSGRKMFRLGNVVHALVAARKTTELPEVLPRICLTASNLTRALYFFCDTVLWLKSVGLQSDIKKAKWQNWATKCYYFSLLMNLARDWYEVSWRLEQAVQEEKMKENCFGDEQPQQRNSSKCNGLHGFLFLLFQILRSHPPLLLDVVKNLCDLSGPLDTLGIYKTNPGVIGFCGLLSSLVGILTLASPHLKLKE", "length": 317 }, "evidence": [ { "id": "A0A4X1U2I9", "url": "https://omabrowser.org/oma/group/A0A4X1U2I9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O70597-1", "protein_name": "Peroxisomal membrane protein 11A", "gene_name": "Pex11a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKAGKEAVVTKLKNLETSVSTGRKWFRLGNVLHAIQATEQSIQATDLVPRLCLTLANLNRVVYYICDTVLWAKSVGLTSGINREKWQMRAARHYYYFLLLSLVRDLYEVLLHMGQVARDRAKREKSSGDPPKYSVANEESEWLQSFLLLLFQSLKRNPPLFLDTVKNFCDILIPLNQLGIYKSNLGVVGFGGLVSSVAGLITVVYPQLKLKAR", "length": 246 }, "evidence": [ { "id": "A0A4X1U2I9", "url": "https://omabrowser.org/oma/group/A0A4X1U2I9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75192-1", "protein_name": "Peroxisomal membrane protein 11A", "gene_name": "PEX11A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRKWFRLGNVVHAIQATEQSIHATDLVPRLCLTLANLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRVTCDRAKKEKSASQDPLWFSVAEEETEWLQSFLLLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITVAYPQMKLKTR", "length": 247 }, "evidence": [ { "id": "A0A4X1U2I9", "url": "https://omabrowser.org/oma/group/A0A4X1U2I9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0VCP2-1", "protein_name": "Peroxisomal membrane protein 11A", "gene_name": "PEX11A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDAFIRFTNQTQGRDRLFRATQYTCMLLRYLLEPKADNEKVVMKLKKLESSVSTGRKWFRLGNVVHALQATQQSVRATDLVPRICLTLASLNRVIYFICDTVLFVRSTGLASGVNKEKWRRWAARYYYYSLLLSLVRDLYEVSLQMKQVAHDRAKREKSPSQDTLGYSVADEETEWLQSLLLLLFHSLKRHPPLFLDTVKNFCDILNPLDQLGIYKSNPGIIGLGGLVSSVAGIITVAYPQMKLKTQ", "length": 247 }, "evidence": [ { "id": "A0A4X1U2I9", "url": "https://omabrowser.org/oma/group/A0A4X1U2I9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9Z211-1", "protein_name": "Peroxisomal membrane protein 11A", "gene_name": "Pex11a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKADKEAVVLKLKRLETSVSTGRKWFRLGNVFHAIQATEQSIQAADLAPRLCLTLANLNRVVYYICDTVLWAKSVGLTSGVNREKWQRWAARHYYYFLLLSLVRDLYEILLQMGQVARDRAKREKSSRDPPKYSVANEETEWLQSFLLLLFQSLKRHPPLLLDTVKNFCDILIPLNQLGIYKSNLGVVGLGGLISSLAGLLTVVYPQLKLKAR", "length": 246 }, "evidence": [ { "id": "A0A4X1U2I9", "url": "https://omabrowser.org/oma/group/A0A4X1U2I9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U2I9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U2I9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U2I9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9" } ], "pmid": "" }, { "name": "peroxisome fission", "id": "GO:0016559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016559", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U2I9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9" } ], "pmid": "" }, { "name": "regulation of peroxisome size", "id": "GO:0044375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044375", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U2I9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U2I9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2I9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U7N1-1", "uniprot_ac": "A0A4X1U7N1", "uniprot_id": "A0A4X1U7N1_PIG", "mass": { "chemical_mass": 70521.0, "monoisotopic_mass": 70521.0 }, "refseq": {}, "gene_names": [ { "name": "GUCY1B1", "type": "recommended", "evidence": [ { "id": "A0A4X1U7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" } ] } ], "protein_names": [ { "name": "Guanylate cyclase soluble subunit beta-1", "type": "recommended", "evidence": [ { "id": "A0A4X1U7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1/entry#names_and_taxonomy" } ] }, { "name": "4.6.1.2", "type": "synonym", "evidence": [ { "id": "A0A4X1U7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1/entry#names_and_taxonomy" } ] }, { "name": "Guanylate cyclase soluble subunit beta-3", "type": "synonym", "evidence": [ { "id": "A0A4X1U7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1/entry#names_and_taxonomy" } ] }, { "name": "Soluble guanylate cyclase small subunit", "type": "synonym", "evidence": [ { "id": "A0A4X1U7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.", "evidence": [ { "database": "UniProtKB", "id": "F1RW97", "url": "https://www.uniprot.org/uniprotkb/F1RW97#function" }, { "database": "UniProtKB", "id": "ARBA00037442", "url": "https://www.uniprot.org/uniprotkb/ARBA00037442#function" }, { "database": "UniProtKB", "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1#function" }, { "database": "UniProtKB", "id": "A0A4X1U7Q8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7Q8#function" }, { "database": "UniProtKB", "id": "A0A4X1U2M3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2M3#function" }, { "database": "UniProtKB", "id": "A0A4X1U516", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U516#function" }, { "database": "UniProtKB", "id": "A0A4X1U721", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U721#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GUCY1B1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1", "locus": { "chromosome": "8", "start_pos": 44604687, "end_pos": 44544179, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008870", "url": "https://www.ensembl.org/id/ENSSSCG00000008870" } ] } } ], "crossref": [ { "id": "A0A4X1U7N1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U7N1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008870", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008870", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07302", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07302", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018297", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018297", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042463", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042463", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SHARCIG", "url": "https://omabrowser.org/oma/group/SHARCIG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR45655", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45655", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45655:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45655:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00211", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00211", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07700", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07700", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-445355", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-445355", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "13665", "url": "https://www.rhea-db.org/rhea/13665", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1U2M3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U2M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U2M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U516", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U516", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U516-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U516-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U721", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U721", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U721-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U721-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U7N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U7Q8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U7Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW97", "url": "https://www.uniprot.org/uniprotkb/F1RW97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW97-1", "url": "https://www.uniprot.org/uniprotkb/F1RW97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTSENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETQQDDN", "length": 619, "header": "tr|A0A4X1U7N1-1|A0A4X1U7N1_PIG Isoform 1 of Guanylate cyclase soluble subunit beta-1 OS=Sus scrofa OX=9823 GN=GUCY1B1 PE=1 SV=1 CANONICAL=A0A4X1U7N1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U2M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1/entry#A0A4X1U2M3-1", "sequence": { "sequence": "IAKSCGEDLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYR", "length": 518, "header": "tr|A0A4X1U2M3-1|A0A4X1U7N1_PIG Computationally mapped isoform of Guanylate cyclase soluble subunit beta-1 OS=Sus scrofa OX=9823 GN=GUCY1B1 PE=1 SV=1 CANONICAL=A0A4X1U7N1-1" }, "locus": { "chromosome": "8", "start_pos": 44601975, "end_pos": 44561762, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057688.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057688.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052255.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052255.2" } ] } }, { "isoform_ac": "A0A4X1U516-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1/entry#A0A4X1U516-1", "sequence": { "sequence": "MFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDGSPTQTQALIGLMALEFHRVGGGSSKALLSICGSVLPLLDRLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTSENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETQQDDN", "length": 591, "header": "tr|A0A4X1U516-1|A0A4X1U516_PIG Computationally mapped isoform of Guanylate cyclase soluble subunit beta-1 OS=Sus scrofa OX=9823 GN=GUCY1B1 PE=1 SV=1 CANONICAL=A0A4X1U7N1-1" }, "locus": { "chromosome": "8", "start_pos": 44603525, "end_pos": 44562685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048626.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048626.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033716.3", "url": "https://www.ensembl.org/id/ENSSSCP00000033716.3" } ] } }, { "isoform_ac": "A0A4X1U721-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1/entry#A0A4X1U721-1", "sequence": { "sequence": "MARRCGKTLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYR", "length": 520, "header": "tr|A0A4X1U721-1|A0A4X1U721_PIG Computationally mapped isoform of Guanylate cyclase soluble subunit beta-1 OS=Sus scrofa OX=9823 GN=GUCY1B1 PE=1 SV=1 CANONICAL=A0A4X1U7N1-1" }, "locus": { "chromosome": "8", "start_pos": 44601975, "end_pos": 44545179, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039198.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039198.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035309.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035309.1" } ] } }, { "isoform_ac": "A0A4X1U7N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1/entry#A0A4X1U7N1-1", "sequence": { "sequence": "MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTSENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETQQDDN", "length": 619, "header": "tr|A0A4X1U7N1-1|A0A4X1U7N1_PIG Isoform 1 of Guanylate cyclase soluble subunit beta-1 OS=Sus scrofa OX=9823 GN=GUCY1B1 PE=1 SV=1 CANONICAL=A0A4X1U7N1-1" }, "locus": { "chromosome": "8", "start_pos": 44603525, "end_pos": 44544503, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062155.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062155.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047708.3", "url": "https://www.ensembl.org/id/ENSSSCP00000047708.3" } ] } }, { "isoform_ac": "A0A4X1U7Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1/entry#A0A4X1U7Q8-1", "sequence": { "sequence": "MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTSENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEKGEWFVLYRNLNDPARPHRLEGTSEYWSPVTMTLGGS", "length": 649, "header": "tr|A0A4X1U7Q8-1|A0A4X1U7Q8_PIG Computationally mapped isoform of Guanylate cyclase soluble subunit beta-1 OS=Sus scrofa OX=9823 GN=GUCY1B1 PE=1 SV=1 CANONICAL=A0A4X1U7N1-1" }, "locus": { "chromosome": "8", "start_pos": 44603012, "end_pos": 44544503, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028460.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028460.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025302.4", "url": "https://www.ensembl.org/id/ENSSSCP00000025302.4" } ] } }, { "isoform_ac": "F1RW97-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1/entry#F1RW97-1", "sequence": { "sequence": "MFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTSENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEV", "length": 545, "header": "tr|F1RW97-1|A0A4X1U7N1_PIG Computationally mapped isoform of Guanylate cyclase soluble subunit beta-1 OS=Sus scrofa OX=9823 GN=GUCY1B1 PE=1 SV=4 CANONICAL=A0A4X1U7N1-1" }, "locus": { "chromosome": "8", "start_pos": 44602428, "end_pos": 44562685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009710.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009710.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009461.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009461.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RW97", "url": "https://www.uniprot.org/uniprotkb/F1RW97" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-445355", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-445355", "resource": "Reactome", "description": "Smooth Muscle Contraction" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAF6YLE3-1", "protein_name": "Guanylate cyclase soluble subunit beta-1", "gene_name": "GUCY1B1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDADKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTASRAFTVHMAPKSKMGSRSTKAALSISHDGSVLISLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETEQDEN", "length": 654 }, "evidence": [ { "id": "A0A4X1U7N1", "url": "https://omabrowser.org/oma/group/A0A4X1U7N1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O54865-1", "protein_name": "Guanylate cyclase soluble subunit beta-1", "gene_name": "Gucy1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRNLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGAEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPLFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETNEEDEN", "length": 620 }, "evidence": [ { "id": "A0A4X1U7N1", "url": "https://omabrowser.org/oma/group/A0A4X1U7N1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P16068-1", "protein_name": "Guanylate cyclase soluble subunit beta-1", "gene_name": "GUCY1B1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDADKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETEQDEN", "length": 619 }, "evidence": [ { "id": "A0A4X1U7N1", "url": "https://omabrowser.org/oma/group/A0A4X1U7N1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P20595-1", "protein_name": "Guanylate cyclase soluble subunit beta-1", "gene_name": "Gucy1b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRSEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQDSRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGKCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGAEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETNQDEN", "length": 619 }, "evidence": [ { "id": "A0A4X1U7N1", "url": "https://omabrowser.org/oma/group/A0A4X1U7N1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q02153-1", "protein_name": "Guanylate cyclase soluble subunit beta-1", "gene_name": "GUCY1B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQDDD", "length": 619 }, "evidence": [ { "id": "A0A4X1U7N1", "url": "https://omabrowser.org/oma/group/A0A4X1U7N1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VA09-1", "protein_name": "Guanylate cyclase soluble subunit beta-1", "gene_name": "Gycbeta100B", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYGFVNYALELLVLKHFGEEIWEKIKKKAMVSMEGQFLVRQIYDDEITYNLIGAAVEILNIPADDILELFGKTFFEFCQDSGYDKILQVLGATPRDFLQNLDALHDHLGTLYPGMRAPSFRCTEKDGELLLHYYSERPGLEHIVIGIVKAVASKLHGVEVEIDIVKRKGEPIDEAEKERAIARENQQLLEDAVATTTTGSATVVLAPSSDAERNNNHNGSNGSNNNGMANNGNTVNVNNNNDGQQIASETDPSIALSTCPIAQDSFDCDGDKEQKCLRLLKNKSDDIERYDHVQFLIREINVAAKSQVDAKKDEVPDDMEFLCEAPLISPATFCKVFPFHLMFDRQMKIVQAGKAVSRVIPRVAEENCSLIEVVEAIRPHLQLNFENILSHINTIYVLQTRQGAMSSRHEQRFLRLKGQMMYIPETDRILFQCYPSVMNLDDLTKKGLYISDVPLHDAARDLVLLSEKFEAEYKLTKNLEMLTDKLQQTFRDLESEKQKTDRLLYSVLPKSVANELRHQRPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELYTVFDALTDSKRNLNVYKVETVGDKYMAVSGLPDHCEDHAKCMARVALDMMDMAKNVKMGSNPVQITIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAINQDDSFHLEYRGPVIMKGKPTPMDCWFLTRATSSILGGTSSTGGSGGGGNGSLDSPLLQPATPTAGAATPIPVVAQRAAGHASVSRTSSAGGGGGGAVVGT", "length": 787 }, "evidence": [ { "id": "A0A4X1U7N1", "url": "https://omabrowser.org/oma/group/A0A4X1U7N1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "guanylate cyclase activity", "id": "GO:0004383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004383", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" } ], "pmid": "" }, { "name": "guanylate cyclase complex, soluble", "id": "GO:0008074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008074", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" } ], "pmid": "" }, { "name": "cGMP biosynthetic process", "id": "GO:0006182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006182", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" } ], "pmid": "" }, { "name": "nitric oxide-cGMP-mediated signaling", "id": "GO:0038060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038060", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" } ], "pmid": "" }, { "name": "response to oxygen levels", "id": "GO:0070482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070482", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U7N1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13665", "name": "", "equation": "GTP = 3',5'-cyclic GMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13665", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13665" } ] }, { "id": "R-SSC-9620456", "name": "sGC stimulators bind sGC:NO", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9620456", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9620456" } ] }, { "id": "R-SSC-9621179", "name": "Cinaciguat binds sGC:NO", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9621179", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9621179" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U7N1" }, { "id": "PS50125", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate cyclase", "eco_id": "ECO_0000259", "start_pos": 421, "end_pos": 554, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 548, "end_pos": 550 }, { "start_pos": 563, "end_pos": 565 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U3A3-1", "uniprot_ac": "A0A4X1U3A3", "uniprot_id": "A0A4X1U3A3_PIG", "mass": { "chemical_mass": 26261.0, "monoisotopic_mass": 26261.0 }, "refseq": {}, "gene_names": [ { "name": "TFPI2", "type": "recommended", "evidence": [ { "id": "A0A4X1U3A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3" } ] } ], "protein_names": [ { "name": "Tissue factor pathway inhibitor", "type": "recommended", "evidence": [ { "id": "A0A4X1U3A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R773", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R773#function" }, { "database": "UniProtKB", "id": "ARBA00060238", "url": "https://www.uniprot.org/uniprotkb/ARBA00060238#function" }, { "database": "UniProtKB", "id": "A0A4X1U3A3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3A3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TFPI2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3", "locus": { "chromosome": "9", "start_pos": 73673535, "end_pos": 73689095, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015322", "url": "https://www.ensembl.org/id/ENSSSCG00000015322" } ] } } ], "crossref": [ { "id": "A0A4X1U3A3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U3A3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015322", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015322", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22615", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22615", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22616", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22616", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "REEYFFN", "url": "https://omabrowser.org/oma/group/REEYFFN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1U3A3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U3A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R773", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R773", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R773-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R773-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSVRTHGLVLLPLLLVGTALGDAPRASPGNYSEICLLPPDEGPCRALVPSYYYDRYTQSCREFMYGGCEGNANNFETWEACDEACWRIEKVPKICRLEVSKRQCGELREEYFFNLSSMTCEKFLSGGCHGNANRFLDEATCMGFCAPKKSPSFCYSPKDEGLCSANVTRYYFNPRHKACETFTYTGCGGNDNNFVSMKDCKRACVKALKKEKKMPRLLLASRRLKIKKKQF", "length": 232, "header": "tr|A0A4X1U3A3-1|A0A4X1U3A3_PIG Isoform 1 of Tissue factor pathway inhibitor OS=Sus scrofa OX=9823 GN=TFPI2 PE=4 SV=1 CANONICAL=A0A4X1U3A3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U3A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3/entry#A0A4X1U3A3-1", "sequence": { "sequence": "MNSVRTHGLVLLPLLLVGTALGDAPRASPGNYSEICLLPPDEGPCRALVPSYYYDRYTQSCREFMYGGCEGNANNFETWEACDEACWRIEKVPKICRLEVSKRQCGELREEYFFNLSSMTCEKFLSGGCHGNANRFLDEATCMGFCAPKKSPSFCYSPKDEGLCSANVTRYYFNPRHKACETFTYTGCGGNDNNFVSMKDCKRACVKALKKEKKMPRLLLASRRLKIKKKQF", "length": 232, "header": "tr|A0A4X1U3A3-1|A0A4X1U3A3_PIG Isoform 1 of Tissue factor pathway inhibitor OS=Sus scrofa OX=9823 GN=TFPI2 PE=4 SV=1 CANONICAL=A0A4X1U3A3-1" }, "locus": { "chromosome": "9", "start_pos": 73688885, "end_pos": 73684976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016695.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016695.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016249.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016249.2" } ] } }, { "isoform_ac": "A0A5G2R773-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3/entry#A0A5G2R773-1", "sequence": { "sequence": "MNSVRTHGLVLLPLLLVGTALGDAPRASPGNYSEICLLPPDEGPCRALVPSYYYDRYTQSCREFMYGGCEGNANNFETWEACDEACWRIEKVPKICRLEVSKRQCGELREEYFFNLSSMTCEKFLSGGCHGNANRFLDEATCMGFCAPKKSPSFCYSPKDEGLCSANVTRYYFNPRHKACETFTYTGCGGNDNNFVSMKDCKRACVKAYGWGSKWS", "length": 216, "header": "tr|A0A5G2R773-1|A0A4X1U3A3_PIG Computationally mapped isoform of Tissue factor pathway inhibitor OS=Sus scrofa OX=9823 GN=TFPI2 PE=4 SV=1 CANONICAL=A0A4X1U3A3-1" }, "locus": { "chromosome": "9", "start_pos": 73688885, "end_pos": 73677582, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074974.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074974.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066451.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066451.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R773", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R773" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q3A7D8-1", "protein_name": "Tissue factor pathway inhibitor", "gene_name": "TFPI2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAGRRLPLPALLLPLACAALAPRGLTEKQRACLLPPDDGPCRALVPRWYYDRYTQSCQEFSYGGCHGNANNFLSHDDCEKNCWTIKKVPKLCRMEADTGPCRGYIRRYAFNLSSMRCEEFIYGGCYGNGNNFKDLQSCVDHCLPEKTGPLLCYSPKDEGLCSSSVPRYYYDTTSKSCKEFKYTGCGGNANNFVTEVDCYNVCRKAGSQKPTINKSRSLLRRKMMRKLIKKPQTHNPKS", "length": 239 }, "evidence": [ { "id": "A0A4X1U3A3", "url": "https://omabrowser.org/oma/group/A0A4X1U3A3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3V7D5-1", "protein_name": "Tissue factor pathway inhibitor 2", "gene_name": "Tfpi2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RPLFWEQTTSTLLPLSAHPGSRTTRSYGPCYIPETVESAAAPGGFSSWSRFSICPRDQKKCRRFKYGGCLGNANNFHSRKLCEHTCGNKEKVPWVCRSAVRTYPCDKPNTEFFFNLKTMTCEPLRPGLCSRTTNVFPEEAMCKSLCEPRKSIPSFCSSPKDEGLCSANVTRYYFNSRNKACETFTYTGCGGNENNFYYLDACNRACVKALKKPKRRKIGDFLPRFWKLRS", "length": 230 }, "evidence": [ { "id": "A0A4X1U3A3", "url": "https://omabrowser.org/oma/group/A0A4X1U3A3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35536-1", "protein_name": "Tissue factor pathway inhibitor 2", "gene_name": "Tfpi2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPAMPLQLWNLPLLLVGSVLGLTSVSAQGNNLEICLLPLDAGPCQALIPKFYYDRDQQKCRRFNYGGCLGNANNFHSRDLCQQTCGSIEKVPPVCRSELKTYPCDKPNIRFFFNLNTMTCEPLRPGLCSRTINVFSEEATCKGLCEPRKHIPSFCSSPKDEGLCSANVTRFYFNSRNKTCETFTYTGCGGNENNFYYLDACHRACVKGWKKPKRWKIGDFLPRFWKHLS", "length": 230 }, "evidence": [ { "id": "A0A4X1U3A3", "url": "https://omabrowser.org/oma/group/A0A4X1U3A3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P48307-1", "protein_name": "Tissue factor pathway inhibitor 2", "gene_name": "TFPI2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPARPLGLSILLLFLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKKKKKMPKLRFASRIRKIRKKQF", "length": 235 }, "evidence": [ { "id": "A0A4X1U3A3", "url": "https://omabrowser.org/oma/group/A0A4X1U3A3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7YRQ8-1", "protein_name": "Tissue factor pathway inhibitor 2", "gene_name": "TFPI2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSVRPLWLMLLSLLLVGTALGDASQAPPGNNAEICLLPPDDGPCRARIPSYYYDRYTQSCREFMYGGCEGNANNFETLEACNEACWKIEKVPKICRLKVNKKQCGELREQYFFNLSSMTCKKFISGGCHSNENRFPDEATCMDFCAPKRAPVFCYSPKDEGLCSANVTRYYFNPRHKACEAFNYTGCGGNDNNFVNLKDCKRTCVKALKKEKNKKMPRLLLANRRLKIKKKQF", "length": 234 }, "evidence": [ { "id": "A0A4X1U3A3", "url": "https://omabrowser.org/oma/group/A0A4X1U3A3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3A3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3A3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3A3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U3A3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U3A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U3A3" }, { "id": "PS50279", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50279" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BPTI/Kunitz inhibitor", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 86, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U497-1", "uniprot_ac": "A0A4X1U497", "uniprot_id": "A0A4X1U497_PIG", "mass": { "chemical_mass": 67755.0, "monoisotopic_mass": 67755.0 }, "refseq": { "ac": "XP_020939167", "name": "RNA polymerase II elongation factor ELL isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939167" }, "gene_names": [ { "name": "ELL", "type": "recommended", "evidence": [ { "id": "A0A4X1U497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ] }, { "name": "ELL", "type": "synonym", "evidence": [ { "id": "XP_020939167", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939167" } ] } ], "protein_names": [ { "name": "Elongation factor for RNA polymerase II", "type": "synonym", "evidence": [ { "id": "A0A4X1U497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497/entry#names_and_taxonomy" } ] }, { "name": "RNA polymerase II elongation factor ELL isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020939167", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939167" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ELL", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497", "locus": { "chromosome": "2", "start_pos": 59359990, "end_pos": 59277184, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040181", "url": "https://www.ensembl.org/id/ENSSSCG00000040181" } ] } } ], "crossref": [ { "id": "A0A4X1U497", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U497", "database": "AlphaFoldDB", "categories": [] }, { "id": "102162997", "url": "https://www.ncbi.nlm.nih.gov/gene/102162997", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QQFQSWH", "url": "https://omabrowser.org/oma/group/QQFQSWH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23288:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07303", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07303", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-112382", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112382", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6796648", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6796648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-75955", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020939167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939167", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U497-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALKEARSYGLSCGRVSDGSKVSVFHVKLTDSALRAFENYRVCQDSVSLRPSIRFQGSQGHISIPQPDCPTEARTFSFYLSNIGRDSPQGSFDCIQQYVSSHGDVHLDCLGSIQDKITVCATDDSYQKARQSLAQAEEETRSRGAIVIKPGGRYLGKKVQFRKPAPGAVDAVPSRKRATPINLASAIKKTSVGSISGASGVSQRPFRDRVLHLLALRPYRKAELLLRLQKDGLVQADKDALDGLLQQVANVNAKDGTWTLKDCVYKDVQKDWPGYSEGDQQLLKRMLIRKLCQSQSTGGLPGDLAANSPPGDHGSSASPPQKRPQPSDFIDPLANKKPRISHFTQRAQPTVNGKLSLPHSREALLPTPGPLAGTDPHLPLRLEPPRSHDPLADVSNDLGHSGRDCEHGEMAAPAPTAHLSLPLLMDCAQPSRPHGSSLHGKSKKKSKKHKDKERAAEDRHQVRPPDHTPGPLEAPSVAPGLNGTCSSSSVPTSTSETPDYLLKYATISSSEQRQSYKNDFNAEYSEYRDLHARIEQITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHSKLAHIKRLIAEYDQRQLQAWP", "length": 613, "header": "tr|A0A4X1U497-1|A0A4X1U497_PIG Isoform 1 of Elongation factor for RNA polymerase II OS=Sus scrofa OX=9823 GN=ELL PE=3 SV=1 CANONICAL=A0A4X1U497-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U497-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497/entry#A0A4X1U497-1", "sequence": { "sequence": "MAALKEARSYGLSCGRVSDGSKVSVFHVKLTDSALRAFENYRVCQDSVSLRPSIRFQGSQGHISIPQPDCPTEARTFSFYLSNIGRDSPQGSFDCIQQYVSSHGDVHLDCLGSIQDKITVCATDDSYQKARQSLAQAEEETRSRGAIVIKPGGRYLGKKVQFRKPAPGAVDAVPSRKRATPINLASAIKKTSVGSISGASGVSQRPFRDRVLHLLALRPYRKAELLLRLQKDGLVQADKDALDGLLQQVANVNAKDGTWTLKDCVYKDVQKDWPGYSEGDQQLLKRMLIRKLCQSQSTGGLPGDLAANSPPGDHGSSASPPQKRPQPSDFIDPLANKKPRISHFTQRAQPTVNGKLSLPHSREALLPTPGPLAGTDPHLPLRLEPPRSHDPLADVSNDLGHSGRDCEHGEMAAPAPTAHLSLPLLMDCAQPSRPHGSSLHGKSKKKSKKHKDKERAAEDRHQVRPPDHTPGPLEAPSVAPGLNGTCSSSSVPTSTSETPDYLLKYATISSSEQRQSYKNDFNAEYSEYRDLHARIEQITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHSKLAHIKRLIAEYDQRQLQAWP", "length": 613, "header": "tr|A0A4X1U497-1|A0A4X1U497_PIG Isoform 1 of Elongation factor for RNA polymerase II OS=Sus scrofa OX=9823 GN=ELL PE=3 SV=1 CANONICAL=A0A4X1U497-1" }, "locus": { "chromosome": "2", "start_pos": 59357988, "end_pos": 59277208, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041528.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041528.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038814.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038814.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 368, "start_aa": "Thr", "end_pos": 368, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr368", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-SSC-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-SSC-6796648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6796648", "resource": "Reactome", "description": "TP53 Regulates Transcription of DNA Repair Genes" }, { "id": "R-SSC-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" }, { "id": "R-SSC-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A753-1", "protein_name": "Elongation factor for RNA polymerase II", "gene_name": "Ell", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALKEARSYGLSCGRVSDGSRVSVFHVKLTDSALKAFESYRAHQDSVSLRPSIRFEGSQGHISIPQPDCPEEVRAFSFYLSNIGRDSPQGSFDCIQQYVSSHGDVHLDCLGSIQDKVTVCATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYMGKKVQFRKPAPGAADAVPSRKRATPINLASAIRKSSGGGASSVVQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKDTLDSLLQQVASVNPKDGTCTLQDCMYKNVQKDWPGYSEGDQQLLKRVLMRKLCQPQSATTDSSPPREHRGSASPSQKRSQQTDFIDPLASKKPRISHFTQRAQPILNGRLGAPNGHETLLPAPVPTPSDTLSSSHLPPRLEPPRTHDPLADVSNDLGHSTQDYKHQEATPAPASRLGLPLLTDFPQAEQPASSSHVHSRPKKKSKKHKDKERPPEERPPAPQPDSSTAPALPTDAPGLNGDCASVPTSTSETPDYLLKYPAISSSEQRQSYKNDFNAEYSEYRSLHARIEQITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSREKRRCEYLHRKLAHIKRLIAEYDQRQLQAWP", "length": 604 }, "evidence": [ { "id": "A0A4X1U497", "url": "https://omabrowser.org/oma/group/A0A4X1U497/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O08856-1", "protein_name": "RNA polymerase II elongation factor ELL", "gene_name": "Ell", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALKEARSYGLSCGRVSDGSRVSVFHVKLTDSALKAFESYRAHQDSVSLRPSIRFEGSQGHISIPQPDCPEEVRAFSFYLSNIGRDSPQGSFDCIQQYVSSYGDVHLDCLGSIQDKVTVCATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYMGKKVQFRKPAPGAADAVPSRKRATPINLASAIRKSSGSGASSVVQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKDTLDSLLQQVASVNPKDGTCTLQDCMYKSLQKDWPGYSEGDRQLLKRMLMRKLCQPQNATTDSSPPREHGRSASPSQKRPTDFIDPLASKKPRISHFTQRAQPTLNGKLGAPNGHETLLPAPGPTPSDTLSSSHLPPRLEPPRTHDPLADVSNDLGHSTQDYKHQEATPAPAPHLGLPLLTDFPQAEQPTSSSHTHSRPKKKSKKHKDKERPPEERPPAPQPDAPTAPALPPDAPGLNGACDNEPTSSSETPDYLLKYPAISSSEQRQSYKNDFNAEYSEYRSLHARIEQITRRFTQLDAQLRQLSQGSDEYETTRGQILQEYRKIKKTNTNYSCEKRRCEYLHRKLAHIKRLIAEYDQRQLQAWP", "length": 602 }, "evidence": [ { "id": "A0A4X1U497", "url": "https://omabrowser.org/oma/group/A0A4X1U497/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P55199-1", "protein_name": "RNA polymerase II elongation factor ELL", "gene_name": "ELL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALKEDRSYGLSCGRVSDGSKVSVFHVKLTDSALRAFESYRARQDSVSLRPSIRFQGSQGHISIPQPDCPAEARTFSFYLSNIGRDNPQGSFDCIQQYVSSHGEVHLDCLGSIQDKITVCATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYLGKKVQFRKPAPGATDAVPSRKRATPINLASAIRKSGASAVSGGSGVSQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKDALDGLLQQVANMSAKDGTCTLQDCMYKDVQKDWPGYSEGDQQLLKRVLVRKLCQPQSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEYSEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHSKLAHIKRLIAEYDQRQLQAWP", "length": 621 }, "evidence": [ { "id": "A0A4X1U497", "url": "https://omabrowser.org/oma/group/A0A4X1U497/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "pmid": "" }, { "name": "histone locus body", "id": "GO:0035363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035363", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase III", "id": "GO:0045945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045945", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase II", "id": "GO:0042795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042795", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase III", "id": "GO:0042796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042796", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U497", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 579, "end_pos": 581, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U497" }, { "id": "PS51980", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51980" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OCEL", "eco_id": "ECO_0000259", "start_pos": 499, "end_pos": 609, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 368 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 483, "end_pos": 485 }, { "start_pos": 579, "end_pos": 581 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U4K8-1", "uniprot_ac": "A0A4X1U4K8", "uniprot_id": "A0A4X1U4K8_PIG", "mass": { "chemical_mass": 12194.0, "monoisotopic_mass": 12194.0 }, "refseq": {}, "gene_names": [ { "name": "TCIM", "type": "recommended", "evidence": [ { "id": "A0A4X1U4K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ] } ], "protein_names": [ { "name": "Transcriptional and immune response regulator", "type": "synonym", "evidence": [ { "id": "A0A4X1U4K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TCIM", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8", "locus": { "chromosome": "17", "start_pos": 9442086, "end_pos": 9441766, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000032320", "url": "https://www.ensembl.org/id/ENSSSCG00000032320" } ] } } ], "crossref": [ { "id": "A0A4X1U4K8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U4K8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100628052", "url": "https://www.ncbi.nlm.nih.gov/gene/100628052", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039580", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039580", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100628052", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100628052", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HGCRFDT", "url": "https://omabrowser.org/oma/group/HGCRFDT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U4K8", "url": "https://www.orthodb.org/?gene=A0A4X1U4K8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32358", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32358", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32358:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32358:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U4K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAKPSHPAVSMSTSLRVSPSIRGYHFDTASRKKAVGNIFENIDQEALQRLFKNSGDKKAEERAKIIFAIDQDLEEKTRALMALKKRTKDKLFQFLKLEKYSIKVH", "length": 106, "header": "tr|A0A4X1U4K8-1|A0A4X1U4K8_PIG Isoform 1 of Transcriptional and immune response regulator OS=Sus scrofa OX=9823 GN=TCIM PE=4 SV=1 CANONICAL=A0A4X1U4K8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U4K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8/entry#A0A4X1U4K8-1", "sequence": { "sequence": "MKAKPSHPAVSMSTSLRVSPSIRGYHFDTASRKKAVGNIFENIDQEALQRLFKNSGDKKAEERAKIIFAIDQDLEEKTRALMALKKRTKDKLFQFLKLEKYSIKVH", "length": 106, "header": "tr|A0A4X1U4K8-1|A0A4X1U4K8_PIG Isoform 1 of Transcriptional and immune response regulator OS=Sus scrofa OX=9823 GN=TCIM PE=4 SV=1 CANONICAL=A0A4X1U4K8-1" }, "locus": { "chromosome": "17", "start_pos": 9442083, "end_pos": 9441766, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043486.2", "url": "https://www.ensembl.org/id/ENSSSCT00000043486.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038190.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038190.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100628052", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100628052", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1C6H3-1", "protein_name": "Transcriptional and immune response regulator", "gene_name": "C8orf4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKAKRRNTASAMSTSLRVSPSVHGYRFDTALRKKAVANIFESVDEESLQKLFKHSGDKKAEERAKIILDTDQDVEEKARALMALKQRRKDKLLQFLKFPKYSIKVH", "length": 106 }, "evidence": [ { "id": "A0A4X1U4K8", "url": "https://omabrowser.org/oma/group/A0A4X1U4K8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HGG0-1", "protein_name": "Transcriptional and immune response regulator", "gene_name": "Tcim", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKAKPSHQATSMSSSLRVSPSIHGYHFDTASRKKAVGNIFENIDQQSLQRLFRNSGDKKAEERAKIILAIDQDLEEKTRALMALKKRTKDKLLQFLRLRKYSIKVH", "length": 106 }, "evidence": [ { "id": "A0A4X1U4K8", "url": "https://omabrowser.org/oma/group/A0A4X1U4K8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5E969-1", "protein_name": "Transcriptional and immune response regulator", "gene_name": "TCIM", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKAKPSHPAFSMSTSLRVSPSIHGYHFDTASRKKAVGNIFENIDQEALQRLFRNSGDKKAEERAKIIFAIDQDLEEKTRALMALKKRTKDKLFQFLKLRKYSIKVH", "length": 106 }, "evidence": [ { "id": "A0A4X1U4K8", "url": "https://omabrowser.org/oma/group/A0A4X1U4K8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D915-1", "protein_name": "Transcriptional and immune response regulator", "gene_name": "Tcim", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKAKPSHQATSMSSSLRVSPSIHGYHFDTAARKKAVGNIFENIDQESLQRLFRNSGDKKAEERAKIIFAIDQDLEEKTRALMALKKRTKDKLLQFLKLRKYSIKVH", "length": 106 }, "evidence": [ { "id": "A0A4X1U4K8", "url": "https://omabrowser.org/oma/group/A0A4X1U4K8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NR00-1", "protein_name": "Transcriptional and immune response regulator", "gene_name": "TCIM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKAKRSHQAVIMSTSLRVSPSIHGYHFDTASRKKAVGNIFENTDQESLERLFRNSGDKKAEERAKIIFAIDQDVEEKTRALMALKKRTKDKLFQFLKLRKYSIKVH", "length": 106 }, "evidence": [ { "id": "A0A4X1U4K8", "url": "https://omabrowser.org/oma/group/A0A4X1U4K8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "pmid": "" }, { "name": "regulation of cell cycle G1/S phase transition", "id": "GO:1902806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902806", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "pmid": "" }, { "name": "endothelial cell activation involved in immune response", "id": "GO:0002264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002264", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U4K8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U4K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U4K8" }, { "id": "PF15063", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15063" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arginine vasopressin-induced protein 1/transcriptional and immune response regulator", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 85, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U5A9-1", "uniprot_ac": "A0A4X1U5A9", "uniprot_id": "A0A4X1U5A9_PIG", "mass": { "chemical_mass": 48293.0, "monoisotopic_mass": 48293.0 }, "refseq": { "ac": "XP_001926024", "name": "monoacylglycerol lipase ABHD2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926024" }, "gene_names": [ { "name": "ABHD2", "type": "recommended", "evidence": [ { "id": "A0A4X1U5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ] }, { "name": "ABHD2", "type": "synonym", "evidence": [ { "id": "XP_001926024", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926024" } ] } ], "protein_names": [ { "name": "Monoacylglycerol lipase ABHD2", "type": "recommended", "evidence": [ { "id": "A0A4X1U5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9/entry#names_and_taxonomy" } ] }, { "name": "2-arachidonoylglycerol hydrolase", "type": "synonym", "evidence": [ { "id": "A0A4X1U5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.23", "type": "synonym", "evidence": [ { "id": "A0A4X1U5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.6", "type": "synonym", "evidence": [ { "id": "A0A4X1U5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.79", "type": "synonym", "evidence": [ { "id": "A0A4X1U5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9/entry#names_and_taxonomy" } ] }, { "name": "Abhydrolase domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "A0A4X1U5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9/entry#names_and_taxonomy" } ] }, { "name": "Acetylesterase", "type": "synonym", "evidence": [ { "id": "A0A4X1U5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9/entry#names_and_taxonomy" } ] }, { "name": "monoacylglycerol lipase ABHD2", "type": "synonym", "evidence": [ { "id": "XP_001926024", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926024" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ABHD2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9", "locus": { "chromosome": "7", "start_pos": 54770131, "end_pos": 54655804, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001835", "url": "https://www.ensembl.org/id/ENSSSCG00000001835" } ] } } ], "crossref": [ { "id": "A0A4X1U5A9", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U5A9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100153434", "url": "https://www.ncbi.nlm.nih.gov/gene/100153434", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153434", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153434", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HCTGEDV", "url": "https://omabrowser.org/oma/group/HCTGEDV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U5A9", "url": "https://www.orthodb.org/?gene=A0A4X1U5A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10794", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10794", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10794:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10794:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001926024", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926024", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12044", "url": "https://www.rhea-db.org/rhea/12044", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "12957", "url": "https://www.rhea-db.org/rhea/12957", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "26132", "url": "https://www.rhea-db.org/rhea/26132", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47348", "url": "https://www.rhea-db.org/rhea/47348", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47392", "url": "https://www.rhea-db.org/rhea/47392", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U5A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNAMLETSELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEHCVGDDVTMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPLTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKRIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKSQCSDTEQVEADLE", "length": 425, "header": "tr|A0A4X1U5A9-1|A0A4X1U5A9_PIG Isoform 1 of Monoacylglycerol lipase ABHD2 OS=Sus scrofa OX=9823 GN=ABHD2 PE=3 SV=1 CANONICAL=A0A4X1U5A9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U5A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9/entry#A0A4X1U5A9-1", "sequence": { "sequence": "MNAMLETSELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEHCVGDDVTMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPLTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKRIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKSQCSDTEQVEADLE", "length": 425, "header": "tr|A0A4X1U5A9-1|A0A4X1U5A9_PIG Isoform 1 of Monoacylglycerol lipase ABHD2 OS=Sus scrofa OX=9823 GN=ABHD2 PE=3 SV=1 CANONICAL=A0A4X1U5A9-1" }, "locus": { "chromosome": "7", "start_pos": 54769959, "end_pos": 54686406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062921.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062921.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036862.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036862.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153434", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153434", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A7W1-1", "protein_name": "Monoacylglycerol lipase ABHD2", "gene_name": "Abhd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEHCVGDDVTMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPQTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKSQCSDTEQMEAELE", "length": 425 }, "evidence": [ { "id": "A0A4X1U5A9", "url": "https://omabrowser.org/oma/group/A0A4X1U5A9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1P1V6-1", "protein_name": "Monoacylglycerol lipase ABHD2", "gene_name": "ABHD2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSVMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPELIYQDSALSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKYLTMPDGATATFDLFEPQSEHCIGEDVTMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNHIKKTYPQTQLVVVGFSLGGNIVCKYLGENQANQERVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQVLFGDNVKKPQSLSDADLSKLYTATSLMQIDDNVMRKFHGYSSLKEYYEEESCLHYLHRIYVPLLLVNAADDPLVHESLLSIPRALSEKKENVMHVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVQYANAICQWEKTKSHCSDTEQAVSGQE", "length": 425 }, "evidence": [ { "id": "A0A4X1U5A9", "url": "https://omabrowser.org/oma/group/A0A4X1U5A9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3IAQ4-1", "protein_name": "Monoacylglycerol lipase ABHD2", "gene_name": "Abhd2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMADGATSTFDLFEPLAEHCVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPQTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLNIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKSQCSDTEQVEAELE", "length": 425 }, "evidence": [ { "id": "A0A4X1U5A9", "url": "https://omabrowser.org/oma/group/A0A4X1U5A9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P08910-1", "protein_name": "Monoacylglycerol lipase ABHD2", "gene_name": "ABHD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEHCVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPLTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKLQCSDTEQVEADLE", "length": 425 }, "evidence": [ { "id": "A0A4X1U5A9", "url": "https://omabrowser.org/oma/group/A0A4X1U5A9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03649-1", "protein_name": "Monoacylglycerol lipase", "gene_name": "MGL2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRLKELLPNFLIVHQEVPEDPIAFKSTDKRENENKEITIPELIDTKVPELADGATDTLYGLLVNGHLQTAYGSFRHFDNIYKVQYKRMIIKYPHGGEGTVDFAVNGRSTKRRKVEKEYVPTSQPVFNGNLKRRYSYYSPDDPKLNSDDAKPMLIILHGLTGGSRESYVRAIVHEITTKYDFEACVFNARGCCYSAITTPLLYNGGWTNDIRYCVNDLRKRFPNRKFYMMGFSLGASIMTNYLGEESDRTKIECAISVSNPFDLYNSAYFINSTPMGSRFYSPALGHNLLRMVRNHLSTLEENPDFKDVIEKHLKKIRTVRQFDNLLTGPMFGYKNAEEYYKNASSYKRIPGIRTPFIALHAQDDPIVGGDLPIDQIKSNPYTLLLETSTGGHVGWFKDRSGRRWYAEPLCRFLKIFHDEITVKGLKPDLENVQLPDPNCEPIATTFRAN", "length": 449 }, "evidence": [ { "id": "A0A4X1U5A9", "url": "https://omabrowser.org/oma/group/A0A4X1U5A9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q24093-1", "protein_name": "Abhydrolase domain-containing protein 2", "gene_name": "Hydr2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTAFLTLIAVIVCILFRILNVHSQPLKPSVWCLDAHFLDCLYKIAPVLREPYIPPRLWGFSGHVQTVLHSIVGRVRCPWPLGERVYMSLKDGSTLTYDLYQPLNEQEDDITVAICPGIANSSESVYIRTFVHLAQCNGYRCAVLNHIGALRSVQVTSTRIFTYGHTEDFAAMVEHLHQKYRQSRIVAVGFSLGGNLVTKYMGEDQKTKPDKVIGGISICQGYNAVEGTKWLLNWQNFRRFYLYIMTENVKSIILRHRHILLSDEVKARHNLNEREIIAAATLPELDEAYTRRVYNFPSTQELYKWSSSLFYFDTIKKPMIFINAKDDPLIPEDLLHPIKEYATTRQNTAYVEVAHGGHLGFYEGGFLYPNPVTWLDRTLVAMVGSLVMMHEVGKVAP", "length": 398 }, "evidence": [ { "id": "A0A4X1U5A9", "url": "https://omabrowser.org/oma/group/A0A4X1U5A9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q54H38-1", "protein_name": "Abhydrolase domain-containing protein", "gene_name": "abhd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSSRDKAEVKLYFDSNNEENQKILDQCPHLYQKYDKDVTINDRINNIEDSEPTIKNGVTFYPPYYLYNSHFMNYYGSYKIPKLNLKTRREILVNPIDGGTISLDFFELGEFKEDTPTIVINHGLTGGSHERYVQYFAQRAYKEKGFRSVVFNYRGCAGNPITADRAYSAVQLDDIKFVTEYLTKTALPLVKKWFLVGFSLGSAILVNYMADAGKDSPYLAHVSISNPMNMVECTKNLSSTYINNLIYNKGLANNLKRLFRKFDGRLDKYATKEQIMAAQTIADFDDLITSKMFGFETAHDYYLAASSSKSIRNLVKPILFINAIDDPIAPTSGFPWKDFKSNPNTILCVSRWGGHLGFISYEDHMSWSDKAAVEYLSTFLDDNNNNNDNDNKTE", "length": 395 }, "evidence": [ { "id": "A0A4X1U5A9", "url": "https://omabrowser.org/oma/group/A0A4X1U5A9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5EA42-1", "protein_name": "Monoacylglycerol lipase ABHD2", "gene_name": "ABHD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNAMMETSELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEHCVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPLTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLAIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKSQCSDTELVEADLE", "length": 425 }, "evidence": [ { "id": "A0A4X1U5A9", "url": "https://omabrowser.org/oma/group/A0A4X1U5A9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q802V6-1", "protein_name": "Monoacylglycerol lipase ABHD2", "gene_name": "abhd2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNTHESEVYTVAPEMPAMFDGMKLAAVATVLYVIVRCLNLKSPTAPPDLTFQDTTLNHFLLKSCPILTKEYIPPLLWGKSGHLQTALYGKLGRVSSPHPFGLRKYLPMQDGATATFDLFEPLADHQSGEDVTMVICPGIGNHSEKHYIRTFVDHSQKQGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFAAMVGFIKKTYPQSKLIVVGFSLGGNIVCKFLGENRTNQERVLCCVSVCQGYSALRAQETFLQWDQCRRFYNFLMADNMKKIILSHRGVLFGVGSKMVDSELSRLYTATSLMQIDDNIMRKFHGHNSLKEYYEKESCVHYIHNINVPLLLVNSVDDPLVHNSLLTIPRTLAEKKENVVFALTLHGGHLGFFEGAVLFPQPLTWMDKVIVDYATAMCQWEKQKPPCQSKDAQSNQTTCQENTS", "length": 432 }, "evidence": [ { "id": "A0A4X1U5A9", "url": "https://omabrowser.org/oma/group/A0A4X1U5A9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9QXM0-1", "protein_name": "Monoacylglycerol lipase ABHD2", "gene_name": "Abhd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEHCVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKRTYPQTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKSQCSDTEQMEAELE", "length": 425 }, "evidence": [ { "id": "A0A4X1U5A9", "url": "https://omabrowser.org/oma/group/A0A4X1U5A9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "acylglycerol catabolic process", "id": "GO:0046464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046464", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" }, { "name": "acrosome reaction", "id": "GO:0007340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007340", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" }, { "name": "response to progesterone", "id": "GO:0032570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032570", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" }, { "name": "steroid hormone receptor signaling pathway", "id": "GO:0043401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043401", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" }, { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" }, { "name": "medium-chain fatty acid catabolic process", "id": "GO:0051793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051793", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" }, { "name": "medium-chain fatty acid biosynthetic process", "id": "GO:0051792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051792", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" }, { "name": "nuclear steroid receptor activity", "id": "GO:0003707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003707", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" }, { "name": "hormone binding", "id": "GO:0042562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042562", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" }, { "name": "acetylesterase activity", "id": "GO:0008126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008126", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" }, { "name": "diacylglycerol lipase activity", "id": "GO:0120516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120516", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" }, { "name": "sperm plasma membrane", "id": "GO:0097524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097524", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5A9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12044", "name": "", "equation": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12044", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12044" } ] }, { "id": "12957", "name": "", "equation": "an acetyl ester + H2O = an aliphatic alcohol + acetate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12957", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12957" } ] }, { "id": "26132", "name": "", "equation": "2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "26132", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/26132" } ] }, { "id": "47348", "name": "", "equation": "a butanoate ester + H2O = an aliphatic alcohol + butanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "47348", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47348" } ] }, { "id": "47392", "name": "", "equation": "hexadecanoate ester + H2O = an aliphatic alcohol + hexadecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "47392", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47392" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5A9" }, { "id": "PF00561", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AB hydrolase-1", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 382, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 410, "end_pos": 412 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U5H3-1", "uniprot_ac": "A0A4X1U5H3", "uniprot_id": "A0A4X1U5H3_PIG", "mass": { "chemical_mass": 45287.0, "monoisotopic_mass": 45287.0 }, "refseq": {}, "gene_names": [ { "name": "SAG", "type": "recommended", "evidence": [ { "id": "A0A4X1U5H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3" } ] } ], "protein_names": [ { "name": "S-arrestin", "type": "recommended", "evidence": [ { "id": "A0A4X1U5H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3/entry#names_and_taxonomy" } ] }, { "name": "48 kDa protein", "type": "synonym", "evidence": [ { "id": "A0A4X1U5H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3/entry#names_and_taxonomy" } ] }, { "name": "Retinal S-antigen", "type": "synonym", "evidence": [ { "id": "A0A4X1U5H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3/entry#names_and_taxonomy" } ] }, { "name": "Rod photoreceptor arrestin", "type": "synonym", "evidence": [ { "id": "A0A4X1U5H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO. May play a role in preventing light-dependent degeneration of retinal photoreceptor cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5H3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3#function" }, { "database": "UniProtKB", "id": "ARBA00045992", "url": "https://www.uniprot.org/uniprotkb/ARBA00045992#function" }, { "database": "UniProtKB", "id": "A0A5G2QN74", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN74#function" }, { "database": "UniProtKB", "id": "A0A5G2RLC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLC1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5H3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SAG", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3", "locus": { "chromosome": "15", "start_pos": 133741798, "end_pos": 133705008, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016301", "url": "https://www.ensembl.org/id/ENSSSCG00000016301" } ] } } ], "crossref": [ { "id": "A0A4X1U5H3", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U5H3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016301", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016301", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QPAPQDM", "url": "https://omabrowser.org/oma/group/QPAPQDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11792", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11792", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11792:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11792:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00339", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00339", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2514859", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2514859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1U5H3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U5H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QN74", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QN74-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAANVQASKSTPNHVIFKKTSRDKSVTIYLGKRDYIDHVDQVEPVDGVVLVDPELVKGKRVYVSLTCAFRYGQEDIDVIGLSFRRDLYFSQVQVFPPVGAASAQTKLQESLIKKLGGHTYPFLLTFPDYLPCSVMLQPAPQDVGKCCGVDFEVKAFATDSADTGEDKIPKKSSVRLLIRKVQHAPLEMGPQPHAEAAWQFFMSDKPLHLTVSLSKELYYHGEPIPVTVTVTNNTEKTVKKIKALVEQVANVVLYSSDYYIKPVATEETQQKVPPNSTLTTTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGMDKTIMGILVSYQIKVQLTVSGLLGELTSSEVATEVPFRLMHPQPEDPEAMDSFQDENFVFEEFARQNLKDAGELKEEKTDQEAAAHE", "length": 407, "header": "tr|A0A4X1U5H3-1|A0A4X1U5H3_PIG Isoform 1 of S-arrestin OS=Sus scrofa OX=9823 GN=SAG PE=1 SV=1 CANONICAL=A0A4X1U5H3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U5H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3/entry#A0A4X1U5H3-1", "sequence": { "sequence": "MAANVQASKSTPNHVIFKKTSRDKSVTIYLGKRDYIDHVDQVEPVDGVVLVDPELVKGKRVYVSLTCAFRYGQEDIDVIGLSFRRDLYFSQVQVFPPVGAASAQTKLQESLIKKLGGHTYPFLLTFPDYLPCSVMLQPAPQDVGKCCGVDFEVKAFATDSADTGEDKIPKKSSVRLLIRKVQHAPLEMGPQPHAEAAWQFFMSDKPLHLTVSLSKELYYHGEPIPVTVTVTNNTEKTVKKIKALVEQVANVVLYSSDYYIKPVATEETQQKVPPNSTLTTTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGMDKTIMGILVSYQIKVQLTVSGLLGELTSSEVATEVPFRLMHPQPEDPEAMDSFQDENFVFEEFARQNLKDAGELKEEKTDQEAAAHE", "length": 407, "header": "tr|A0A4X1U5H3-1|A0A4X1U5H3_PIG Isoform 1 of S-arrestin OS=Sus scrofa OX=9823 GN=SAG PE=1 SV=1 CANONICAL=A0A4X1U5H3-1" }, "locus": { "chromosome": "15", "start_pos": 133741705, "end_pos": 133706284, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017752.3", "url": "https://www.ensembl.org/id/ENSSSCT00000017752.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017271.3", "url": "https://www.ensembl.org/id/ENSSSCP00000017271.3" } ] } }, { "isoform_ac": "A0A5G2QN74-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3/entry#A0A5G2QN74-1", "sequence": { "sequence": "MAANVQASKSTPNHVIFKKTSRDKSVTIYLGKRDYIDHVDQVEPVGKLSLDPPPPVSLPVYVSLTCAFRYGQEDIDVIGLSFRRDLYFSQVQVFPPVGAASAQTKLQESLIKKLGGHTYPFLLTFPDYLPCSVMLQPAPQDVGKCCGVDFEVKAFATDSADTGEDKIPKKSSVRLLIRKVQHAPLEMGPQPHAEAAWQFFMSDKPLHLTVSLSKELYYHGEPIPVTVTVTNNTEKTVKKIKALVEQVANVVLYSSDYYIKPVATEETQQKVPPNSTLTTTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGMDKTIMGILVSYQIKVQLTLRSHCSAFSFSSEVATEVPFRLMHPQPEDPGHFQDENFVFEEFARQNLKDAGELKEEKTDQEAAAHE", "length": 404, "header": "tr|A0A5G2QN74-1|A0A5G2QN74_PIG Computationally mapped isoform of S-arrestin OS=Sus scrofa OX=9823 GN=SAG PE=1 SV=1 CANONICAL=A0A4X1U5H3-1" }, "locus": { "chromosome": "15", "start_pos": 133741705, "end_pos": 133706284, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085637.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085637.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063558.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063558.1" } ] } }, { "isoform_ac": "A0A5G2RLC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3/entry#A0A5G2RLC1-1", "sequence": { "sequence": "MAANVQASKSTPNHVIFKKTSRDKSVTIYLGKRDYIDHVDQVEPVGKLSLDPPPPVSLPVYVSLTCAFRYGQEDIDVIGLSFRRDLYFSQVQVFPPVGAASAQTKLQESLIKKLGGHTYPFLLTFPDYLPCSVMLQPAPQDVGKCCGVDFEVKAFATDSADTGEDKIPKKSSVRLLIRKVQHAPLEMGPQPHAEAAWQFFMSDKPLHLTVSLSKELYYHGEPIPVTVTVTNNTEKTVKKIKALVEQVANVVLYSSDYYIKPVATEETQQKVPPNSTLTTTLTLVPLLANNRERRGIALDGKIKHEDTNLASTSEKICRHSSQPGDLQLRSHCSAFSFSSEVATEVPFRLMHPQPEDPGHFQDENFVFEEFARQNLKDAGELKEEKTDQEAAAHE", "length": 394, "header": "tr|A0A5G2RLC1-1|A0A4X1U5H3_PIG Computationally mapped isoform of S-arrestin OS=Sus scrofa OX=9823 GN=SAG PE=1 SV=2 CANONICAL=A0A4X1U5H3-1" }, "locus": { "chromosome": "15", "start_pos": 133741705, "end_pos": 133706284, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085118.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085118.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073073.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073073.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLC1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLC1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2514859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2514859", "resource": "Reactome", "description": "Inactivation, recovery and regulation of the phototransduction cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "P08168-1", "protein_name": "S-arrestin", "gene_name": "SAG", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKANKPAPNHVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVYVSLTCAFRYGQEDIDVMGLSFRRDLYFSQVQVFPPVGASGATTRLQESLIKKLGANTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEIKAFATHSTDVEEDKIPKKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVSLSKEIYYHGEPIPVTVAVTNSTEKTVKKIKVLVEQVTNVVLYSSDYYIKTVAAEEAQEKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDKTVMGILVSYQIKVKLTVSGLLGELTSSEVATEVPFRLMHPQPEDPDTAKESFQDENFVFEEFARQNLKDAGEYKEEKTDQEAAMDE", "length": 404 }, "evidence": [ { "id": "A0A4X1U5H3", "url": "https://omabrowser.org/oma/group/A0A4X1U5H3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P10523-1", "protein_name": "S-arrestin", "gene_name": "SAG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASGKTSKSEPNHVIFKKISRDKSVTIYLGNRDYIDHVSQVQPVDGVVLVDPDLVKGKKVYVTLTCAFRYGQEDIDVIGLTFRRDLYFSRVQVYPPVGAASTPTKLQESLLKKLGSNTYPFLLTFPDYLPCSVMLQPAPQDSGKSCGVDFEVKAFATDSTDAEEDKIPKKSSVRLLIRKVQHAPLEMGPQPRAEAAWQFFMSDKPLHLAVSLNKEIYFHGEPIPVTVTVTNNTEKTVKKIKAFVEQVANVVLYSSDYYVKPVAMEEAQEKVPPNSTLTKTLTLLPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDRTVLGILVSYQIKVKLTVSGFLGELTSSEVATEVPFRLMHPQPEDPAKESYQDANLVFEEFARHNLKDAGEAEEGKRDKNDVDE", "length": 405 }, "evidence": [ { "id": "A0A4X1U5H3", "url": "https://omabrowser.org/oma/group/A0A4X1U5H3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15887-1", "protein_name": "S-arrestin", "gene_name": "Sag", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAACVKTNKSHVIFKKVSRDKSVTIYLGKRDYIDHVSQVEPVDGVVLVDPELVKGKKVYVTLTCAFRYGQEDIDVIGLTFRRDLYFSRVQVYPPVGAMSAPTQLQLSLLKKLGDNTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEVKAFATDITDAEEDKIPKKSSVRLLIRKVQHAPPEMGPQPCAEASWQFFMSDKPLHLSVSLSKEIYFHGEPIPVTVTVTNNTEKVVKKIKVSVEQIANVVLYSSDYYVKPVASEETQEKVQPNSTLTKTLVLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDRTVMGILVSYHIKVKLTVSGFLGELTSSEVATEVPFRLMHPQPEDPAKESVQDENLVFEEFARQNLKDTGENTEGKKDEDAGQDE", "length": 403 }, "evidence": [ { "id": "A0A4X1U5H3", "url": "https://omabrowser.org/oma/group/A0A4X1U5H3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P20443-1", "protein_name": "S-arrestin", "gene_name": "Sag", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAACGKTNKSHVIFKKVSRDKSVTIYLGKRDYVDHVSQVEPVDGVVLVDPELVKGKKVYVTLTCAFRYGQEDIDVMGLTFRRDLYFSRVQVYPPVGAMSVLTQLQESLLKKLGDNTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEVKAFASDITDPEEDKIPKKSSVRLLIRKVQHAPPEMGPQPSAEASWQFFMSDKPLNLSVSLSKEIYFHGEPIPVTVTVTNNTDKVVKKIKVSVEQIANVVLYSSDYYVKPVASEETQEKVQPNSTLTKTLVLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDRTVMGILVSYHIKVKLTVSGFLGELTSSEVATEVPFRLMHPQPEDPAKESVQDENLVFEEFARQNLKDTGENTEGKKDEDAGQDE", "length": 403 }, "evidence": [ { "id": "A0A4X1U5H3", "url": "https://omabrowser.org/oma/group/A0A4X1U5H3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5H3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3" } ], "pmid": "" }, { "name": "sensory perception", "id": "GO:0007600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007600", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5H3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3" } ], "pmid": "" }, { "name": "G protein-coupled receptor internalization", "id": "GO:0002031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002031", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5H3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5H3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3" } ], "pmid": "" }, { "name": "phosphoprotein binding", "id": "GO:0051219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051219", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5H3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3" } ], "pmid": "" }, { "name": "opsin binding", "id": "GO:0002046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002046", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5H3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5H3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U5H3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U5H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U5H3" }, { "id": "SM01017", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arrestin C-terminal-like", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 364, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 }, { "start_pos": 275, "end_pos": 277 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U699-1", "uniprot_ac": "A0A4X1U699", "uniprot_id": "A0A4X1U699_PIG", "mass": { "chemical_mass": 35094.0, "monoisotopic_mass": 35094.0 }, "refseq": { "ac": "XP_003122180", "name": "olfactory receptor 1J4-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122180" }, "gene_names": [ { "name": "LOC100524234", "type": "recommended", "evidence": [ { "id": "A0A4X1U699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699" } ] }, { "name": "LOC100524234", "type": "synonym", "evidence": [ { "id": "XP_003122180", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122180" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1U699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1J4-like", "type": "synonym", "evidence": [ { "id": "XP_003122180", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122180" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U699", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U699", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100524234", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699", "locus": {} } ], "crossref": [ { "id": "A0A4X1U699", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U699", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524234", "url": "https://www.ncbi.nlm.nih.gov/gene/100524234", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524234", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524234", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1U699", "url": "https://www.orthodb.org/?gene=A0A4X1U699", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003122180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122180", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U699", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U699-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315, "header": "tr|A0A4X1U699-1|A0A4X1U699_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524234 PE=3 SV=1 CANONICAL=A0A4X1U699-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U699-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699/entry#A0A4X1U699-1", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315, "header": "tr|A0A4X1U699-1|A0A4X1U699_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100524234 PE=3 SV=1 CANONICAL=A0A4X1U699-1" }, "locus": { "chromosome": "AEMK02000598.1", "start_pos": 1225047, "end_pos": 1224103, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105452.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105452.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077062.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077062.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U699", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524234", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524234", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "A0A4X1U699", "url": "https://omabrowser.org/oma/group/A0A4X1U699/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U699", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U699", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U699", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U699", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U699" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 292, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U6C4-1", "uniprot_ac": "A0A4X1U6C4", "uniprot_id": "A0A4X1U6C4_PIG", "mass": { "chemical_mass": 68700.0, "monoisotopic_mass": 68700.0 }, "refseq": { "ac": "XP_020940307", "name": "protein fem-1 homolog C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940307" }, "gene_names": [ { "name": "FEM1C", "type": "recommended", "evidence": [ { "id": "A0A4X1U6C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4" } ] }, { "name": "FEM1C", "type": "synonym", "evidence": [ { "id": "XP_020940307", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940307" } ] } ], "protein_names": [ { "name": "Protein fem-1 homolog C", "type": "recommended", "evidence": [ { "id": "A0A4X1U6C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4/entry#names_and_taxonomy" } ] }, { "name": "FEM1-gamma", "type": "synonym", "evidence": [ { "id": "A0A4X1U6C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4/entry#names_and_taxonomy" } ] }, { "name": "protein fem-1 homolog C", "type": "synonym", "evidence": [ { "id": "XP_020940307", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940307" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6C4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FEM1C", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4", "locus": { "chromosome": "2", "start_pos": 119699598, "end_pos": 119722806, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014217", "url": "https://www.ensembl.org/id/ENSSSCG00000014217" } ] } } ], "crossref": [ { "id": "ENSSSCG00000014217", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014217", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100623242", "url": "https://www.ncbi.nlm.nih.gov/gene/100623242", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623242", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623242", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FMTTEWR", "url": "https://omabrowser.org/oma/group/FMTTEWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U6C4", "url": "https://www.orthodb.org/?gene=A0A4X1U6C4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020940307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940307", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U6C4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U6C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RLE6", "url": "https://www.uniprot.org/uniprotkb/F1RLE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RLE6-1", "url": "https://www.uniprot.org/uniprotkb/F1RLE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQNNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR", "length": 617, "header": "tr|A0A4X1U6C4-1|A0A4X1U6C4_PIG Isoform 1 of Protein fem-1 homolog C OS=Sus scrofa OX=9823 GN=FEM1C PE=3 SV=1 CANONICAL=A0A4X1U6C4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U6C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4/entry#A0A4X1U6C4-1", "sequence": { "sequence": "MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQNNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR", "length": 617, "header": "tr|A0A4X1U6C4-1|A0A4X1U6C4_PIG Isoform 1 of Protein fem-1 homolog C OS=Sus scrofa OX=9823 GN=FEM1C PE=3 SV=1 CANONICAL=A0A4X1U6C4-1" }, "locus": { "chromosome": "2", "start_pos": 119721626, "end_pos": 119702890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041545.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041545.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045052.1", "url": "https://www.ensembl.org/id/ENSSSCP00000045052.1" } ] } }, { "isoform_ac": "F1RLE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4/entry#F1RLE6-1", "sequence": { "sequence": "MDELCGRRRSNAARAAARTTVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQNNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR", "length": 607, "header": "tr|F1RLE6-1|A0A4X1U6C4_PIG Computationally mapped isoform of Protein fem-1 homolog C OS=Sus scrofa OX=9823 GN=FEM1C PE=3 SV=4 CANONICAL=A0A4X1U6C4-1" }, "locus": { "chromosome": "2", "start_pos": 119722782, "end_pos": 119702890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015535.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015535.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015123.4", "url": "https://www.ensembl.org/id/ENSSSCP00000015123.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RLE6", "url": "https://www.uniprot.org/uniprotkb/F1RLE6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623242", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623242", "resource": "KEGG Pathway" }, { "id": "R-SSC-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A7MB89-1", "protein_name": "Protein fem-1 homolog C", "gene_name": "FEM1C", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQNNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR", "length": 617 }, "evidence": [ { "id": "A0A4X1U6C4", "url": "https://omabrowser.org/oma/group/A0A4X1U6C4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZZR4-1", "protein_name": "Protein fem-1 homolog C", "gene_name": "Fem1c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLKTAVFNAARDGKLRLLTKLLASKSKAEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGNIPEKLETFVSLHR", "length": 617 }, "evidence": [ { "id": "A0A4X1U6C4", "url": "https://omabrowser.org/oma/group/A0A4X1U6C4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C5C6-1", "protein_name": "Protein fem-1 homolog C", "gene_name": "FEM1C", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDLKTAVFNAAREGKLRLLSKLLASKTKEEVALLVSEKTDGATPLLVAARYGHLDMVEYLLDHCSASIEVGGSVSFDGETIEGAPPLWAASAAGHLNVVQSLLDRGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLEIMKMLLKYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTQHVQTSKAECINALELLGATFVDKKRDLLGALKYWKRAMEMRYSDRTNILSKPVPQTLIMAYAYAKEVNSSEELENLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTSSSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAMKQTQCPPDPIQLNKALAIILHLICLLEKVPCSSEQEYFKKQTIYKFLKLQPRGKNNFSPLHLAVDNSTTCVGRYPVCKFPSLQVTAILVECGADVNVRDSDNNSPLHIAALNNHPDIMNFLINSGSHFDATNSHRKTASDLLDDKEIAKNLIQPINHITLQCLAARVVVNRNIRYAGHIPEKLENFILLHR", "length": 617 }, "evidence": [ { "id": "A0A4X1U6C4", "url": "https://omabrowser.org/oma/group/A0A4X1U6C4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8CEF1-1", "protein_name": "Protein fem-1 homolog C", "gene_name": "Fem1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLKTAVFNAARDGKLRLLTKLLASKSKAEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQLNKALSIILHLICLLEKVPCTVEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGNIPEKLETFVSLHR", "length": 617 }, "evidence": [ { "id": "A0A4X1U6C4", "url": "https://omabrowser.org/oma/group/A0A4X1U6C4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JP0-1", "protein_name": "Protein fem-1 homolog C", "gene_name": "FEM1C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR", "length": 617 }, "evidence": [ { "id": "A0A4X1U6C4", "url": "https://omabrowser.org/oma/group/A0A4X1U6C4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VFD5-1", "protein_name": "Protein fem-1 homolog CG6966", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYKFIVFNAARDNNLAQLKATLYNKSSVEVGSLISAKVNGATPLVISCRNGHYDIVEYLLTKCRANVEQVGSVSFDGEPIEDAPPLWCAAAAGHLGIVKMLVRRGANVNSTTRTNSTPLRAACFDGHYEIVKYLVHHGADFEVANRHGHTCLMIACYKGHFRIAQYLLSLNADVNRCSVKGNTALHDCAESGSLQILQLLLKHGATMDVDYYGMTPLLAASVTGHMPIVEHLITLPCVSRESRIHALELLGATYVDRKRDMAAALNLWRRALEERAVEPPLEKKVQEPVPAYEMVREVTSVEELEEMVLDPDEMRMQALVIRQRILGPTHPDTSYYIRFRGAHYADAGRFDRCIELWSYALTMQQKILQPLSPMTQSSLLSFAELFSFMLVEAGRLLPRGRVVPPIEPDSMLTIFYKAVKEVERGLAFTLEQQKDQQHPQKQLPAADKSPSCSASSSASSSSSTTLLSAHQHDCNHDPNALSRTMISAIHIGCLLSSLLDTDALSPEMRRQVMGALYRLNRLKVRVRFDRTALHYACYREGTLAGRYPSCQFPSVTLAKALLEVGADPNAIDEAGNTPLHLATMQPYVEPLSHILLEGGAHLDTKNYAGETFESLLAPTPMHKIIDPMKYTTLACLAARTIKKHDIRYEGTVPATLYEFIELH", "length": 664 }, "evidence": [ { "id": "A0A4X1U6C4", "url": "https://omabrowser.org/oma/group/A0A4X1U6C4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6C4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6C4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6C4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4" } ], "pmid": "" }, { "name": "Cul2-RING ubiquitin ligase complex", "id": "GO:0031462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031462", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6C4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6C4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the C-end degron rule pathway", "id": "GO:0140627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140627", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6C4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6C4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6C4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 111, "end_pos": 113 }, { "start_pos": 116, "end_pos": 118 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 582, "end_pos": 584 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U6F0-1", "uniprot_ac": "A0A4X1U6F0", "uniprot_id": "A0A4X1U6F0_PIG", "mass": { "chemical_mass": 39206.0, "monoisotopic_mass": 39206.0 }, "refseq": { "ac": "XP_003480474", "name": "galanin receptor type 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480474" }, "gene_names": [ { "name": "GALR1", "type": "recommended", "evidence": [ { "id": "A0A4X1U6F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0" } ] }, { "name": "GALR1", "type": "synonym", "evidence": [ { "id": "XP_003480474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480474" } ] } ], "protein_names": [ { "name": "Galanin receptor type 1", "type": "recommended", "evidence": [ { "id": "A0A4X1U6F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0/entry#names_and_taxonomy" } ] }, { "name": "galanin receptor type 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003480474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480474" } ] } ], "function": [ { "annotation": "Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6F0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0#function" }, { "database": "UniProtKB", "id": "ARBA00053116", "url": "https://www.uniprot.org/uniprotkb/ARBA00053116#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6F0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GALR1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0", "locus": { "chromosome": "1", "start_pos": 147443821, "end_pos": 147463542, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036984", "url": "https://www.ensembl.org/id/ENSSSCG00000036984" } ] } } ], "crossref": [ { "id": "A0A4X1U6F0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U6F0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15098", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15098", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100736969", "url": "https://www.ncbi.nlm.nih.gov/gene/100736969", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100736969", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736969", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CWEQWPD", "url": "https://omabrowser.org/oma/group/CWEQWPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U6F0", "url": "https://www.orthodb.org/?gene=A0A4X1U6F0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003480474", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480474", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U6F0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U6F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELAAGNLSEGNESWPEPPTLEPRPLFGIGVENFITLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLVAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYHQRLFHRGVGNQTFCWEQWPNQHHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGVSWLPHHVIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIGKESPLHDTKENKSRLDTPPSTNCTHV", "length": 349, "header": "tr|A0A4X1U6F0-1|A0A4X1U6F0_PIG Isoform 1 of Galanin receptor type 1 OS=Sus scrofa OX=9823 GN=GALR1 PE=3 SV=1 CANONICAL=A0A4X1U6F0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U6F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0/entry#A0A4X1U6F0-1", "sequence": { "sequence": "MELAAGNLSEGNESWPEPPTLEPRPLFGIGVENFITLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLVAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYHQRLFHRGVGNQTFCWEQWPNQHHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGVSWLPHHVIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIGKESPLHDTKENKSRLDTPPSTNCTHV", "length": 349, "header": "tr|A0A4X1U6F0-1|A0A4X1U6F0_PIG Isoform 1 of Galanin receptor type 1 OS=Sus scrofa OX=9823 GN=GALR1 PE=3 SV=1 CANONICAL=A0A4X1U6F0-1" }, "locus": { "chromosome": "1", "start_pos": 147462396, "end_pos": 147449880, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081092.1", "url": "https://www.ensembl.org/id/ENSSSCT00000081092.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071771.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071771.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6F0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100736969", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736969", "resource": "KEGG Pathway" }, { "id": "R-SSC-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BCM7-1", "protein_name": "Galanin receptor type 1", "gene_name": "GALR1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELEVGNFSEGNASGLEPPTPDPRPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSALRVSRNALLGVGFIWALSIAMASPVAYHQRLFHRDVSNQTFCWEQWPNQRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNVSKKSEASKKKTAQTVLVVVVVFGVSWLPHHVIHLWAEFGVFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHARKESPLNDTKENKSRLDTPPSTNCTHV", "length": 349 }, "evidence": [ { "id": "A0A4X1U6F0", "url": "https://omabrowser.org/oma/group/A0A4X1U6F0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3I6F5-1", "protein_name": "Galanin receptor type 1", "gene_name": "Galr1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MELATLNLSEGNEGNGSDPEPPAAVESRLLFGIGVENFITLVVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFTHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYHQRLYYRDNNQTFCWELWPNQLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVVHLWAEFGAFPLTQASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIHKSVPSDTKENKSRIDTPPSTNCTHV", "length": 351 }, "evidence": [ { "id": "A0A4X1U6F0", "url": "https://omabrowser.org/oma/group/A0A4X1U6F0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P47211-1", "protein_name": "Galanin receptor type 1", "gene_name": "GALR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNCTHV", "length": 349 }, "evidence": [ { "id": "A0A4X1U6F0", "url": "https://omabrowser.org/oma/group/A0A4X1U6F0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P56479-1", "protein_name": "Galanin receptor type 1", "gene_name": "Galr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELAMVNLSEGNGSDPEPPAPESRPLFGIGVENFITLVVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYHQRLFHRDSNQTFCWEQWPNKLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVVHLWAEFGAFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHVCDESPRSETKENKSRMDTPPSTNCTHV", "length": 348 }, "evidence": [ { "id": "A0A4X1U6F0", "url": "https://omabrowser.org/oma/group/A0A4X1U6F0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62805-1", "protein_name": "Galanin receptor type 1", "gene_name": "Galr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELAPVNLSEGNGSDPEPPAEPRPLFGIGVENFITLVVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYYQRLFHRDSNQTFCWEHWPNQLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVIHLWAEFGAFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCRVCNESPHGDAKEKNRIDTPPSTNCTHV", "length": 346 }, "evidence": [ { "id": "A0A4X1U6F0", "url": "https://omabrowser.org/oma/group/A0A4X1U6F0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6F0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6F0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0" } ], "pmid": "" }, { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6F0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6F0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0" } ], "pmid": "" }, { "name": "positive regulation of cortisol secretion", "id": "GO:0051464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051464", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6F0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6F0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0" } ], "pmid": "" }, { "name": "galanin receptor activity", "id": "GO:0004966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004966", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6F0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U6F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6F0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 303, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 76, "end_pos": 78 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U6X7-1", "uniprot_ac": "A0A4X1U6X7", "uniprot_id": "A0A4X1U6X7_PIG", "mass": { "chemical_mass": 78984.0, "monoisotopic_mass": 78984.0 }, "refseq": { "ac": "XP_020954462", "name": "U3 small nucleolar ribonucleoprotein protein MPP10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954462" }, "gene_names": [ { "name": "MPHOSPH10", "type": "recommended", "evidence": [ { "id": "A0A4X1U6X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7" } ] }, { "name": "MPHOSPH10", "type": "synonym", "evidence": [ { "id": "XP_020954462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954462" } ] } ], "protein_names": [ { "name": "U3 small nucleolar ribonucleoprotein protein MPP10", "type": "recommended", "evidence": [ { "id": "A0A4X1U6X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7/entry#names_and_taxonomy" } ] }, { "name": "U3 small nucleolar ribonucleoprotein protein MPP10", "type": "synonym", "evidence": [ { "id": "XP_020954462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954462" } ] } ], "function": [ { "annotation": "Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6X7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7#function" }, { "database": "UniProtKB", "id": "PIRNR017300", "url": "https://www.uniprot.org/uniprotkb/PIRNR017300#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6X7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MPHOSPH10", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7", "locus": { "chromosome": "1", "start_pos": 143972596, "end_pos": 143994041, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004847", "url": "https://www.ensembl.org/id/ENSSSCG00000004847" } ] } } ], "crossref": [ { "id": "A0A4X1U6X7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U6X7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100153310", "url": "https://www.ncbi.nlm.nih.gov/gene/100153310", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153310", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153310", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1U6X7", "url": "https://www.orthodb.org/?gene=A0A4X1U6X7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17039", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17039", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17039:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17039:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04006", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04006", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020954462", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954462", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U6X7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U6X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRVWRRQTLERCLREVGKATDQPERFLTIQDELASNFTSLTKVLYDFNKVLEKDRKHGSPLQRLMIHNFDDEQIWQQLELQNEPILQYLQNAVSETIKDEDITLLPENEEQECEEDALEMEAGGQEDLEKELSEVEEEEVSDLSGDDLEGDERSKNSSKLDLRKSPDFSDEDSDLDFDIGKLEQQSKVQNRVPRKPTEKSVVDDKFFKLSEMETFLENIEKEEEQQKDDEEEDIDFFEDVDSDEGEGGLFRSQNLKSGKSSRNLKYKDFFDPVESDEDIASIHDDELASHEEEEIAEEGEQSISEMEEDNDLEESRDSKQHKETLKRVTFALPDDEEPEDTDVLNIQKDSDEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLLGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLQLEDIIKQRIKDQAWDDVVRKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEEENPEHVEIQKMMDSLFLKLDALSNFHFIPKPPVPEIKVVSNLPAITMEEVAPVSVSDAALLAPEEVKEKNKAGDIKTAAEKTATDKKRERRKKKHQKHMKIKEKEKRRRLLEKSNPDQAGKYTKAVASEKLKQLTKTGKASLLKDEGKDKALKSSQAFFSKLQDQVKMQINDAKKTEKKKKKKQDISVHKLKL", "length": 680, "header": "tr|A0A4X1U6X7-1|A0A4X1U6X7_PIG Isoform 1 of U3 small nucleolar ribonucleoprotein protein MPP10 OS=Sus scrofa OX=9823 GN=MPHOSPH10 PE=3 SV=1 CANONICAL=A0A4X1U6X7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U6X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7/entry#A0A4X1U6X7-1", "sequence": { "sequence": "MAPRVWRRQTLERCLREVGKATDQPERFLTIQDELASNFTSLTKVLYDFNKVLEKDRKHGSPLQRLMIHNFDDEQIWQQLELQNEPILQYLQNAVSETIKDEDITLLPENEEQECEEDALEMEAGGQEDLEKELSEVEEEEVSDLSGDDLEGDERSKNSSKLDLRKSPDFSDEDSDLDFDIGKLEQQSKVQNRVPRKPTEKSVVDDKFFKLSEMETFLENIEKEEEQQKDDEEEDIDFFEDVDSDEGEGGLFRSQNLKSGKSSRNLKYKDFFDPVESDEDIASIHDDELASHEEEEIAEEGEQSISEMEEDNDLEESRDSKQHKETLKRVTFALPDDEEPEDTDVLNIQKDSDEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLLGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLQLEDIIKQRIKDQAWDDVVRKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEEENPEHVEIQKMMDSLFLKLDALSNFHFIPKPPVPEIKVVSNLPAITMEEVAPVSVSDAALLAPEEVKEKNKAGDIKTAAEKTATDKKRERRKKKHQKHMKIKEKEKRRRLLEKSNPDQAGKYTKAVASEKLKQLTKTGKASLLKDEGKDKALKSSQAFFSKLQDQVKMQINDAKKTEKKKKKKQDISVHKLKL", "length": 680, "header": "tr|A0A4X1U6X7-1|A0A4X1U6X7_PIG Isoform 1 of U3 small nucleolar ribonucleoprotein protein MPP10 OS=Sus scrofa OX=9823 GN=MPHOSPH10 PE=3 SV=1 CANONICAL=A0A4X1U6X7-1" }, "locus": { "chromosome": "1", "start_pos": 143993233, "end_pos": 143972695, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005348.4", "url": "https://www.ensembl.org/id/ENSSSCT00000005348.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005216.3", "url": "https://www.ensembl.org/id/ENSSSCP00000005216.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6X7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153310", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153310", "resource": "KEGG Pathway" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6X7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7" } ], "pmid": "" }, { "name": "sno(s)RNA-containing ribonucleoprotein complex", "id": "GO:0005732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005732", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6X7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7" } ], "pmid": "" }, { "name": "Mpp10 complex", "id": "GO:0034457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034457", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6X7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6X7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6X7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U6X7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U6X7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 38, "end_pos": 40 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U758-1", "uniprot_ac": "A0A4X1U758", "uniprot_id": "A0A4X1U758_PIG", "mass": { "chemical_mass": 9384.0, "monoisotopic_mass": 9384.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "60S ribosomal protein L39-like", "type": "recommended", "evidence": [ { "id": "A0A4X1U758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U758/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U758", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U758" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U758", "locus": {} } ], "crossref": [ { "id": "A0A4X1U758", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U758", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19970", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19970", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19970:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19970:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1U758", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U758", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U758-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U758-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSDKTFRIKQFLVKKQKQNCPVPQWIRMKTGNKIRYNPWPCSRRHWRRTKLGLSGASAYGLAHIFMLCGITCLHLILSH", "length": 80, "header": "tr|A0A4X1U758-1|A0A4X1U758_PIG Isoform 1 of 60S ribosomal protein L39-like OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1U758-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U758-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U758/entry#A0A4X1U758-1", "sequence": { "sequence": "MSSDKTFRIKQFLVKKQKQNCPVPQWIRMKTGNKIRYNPWPCSRRHWRRTKLGLSGASAYGLAHIFMLCGITCLHLILSH", "length": 80, "header": "tr|A0A4X1U758-1|A0A4X1U758_PIG Isoform 1 of 60S ribosomal protein L39-like OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A4X1U758-1" }, "locus": { "chromosome": "9", "start_pos": 120546176, "end_pos": 120545852, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084383.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084383.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068037.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068037.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U758", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U758" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U758", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U758" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U758", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U758" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U758", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U758" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U843-1", "uniprot_ac": "A0A4X1U843", "uniprot_id": "A0A4X1U843_PIG", "mass": { "chemical_mass": 9338.0, "monoisotopic_mass": 9338.0 }, "refseq": { "ac": "XP_005657678", "name": "V-type proton ATPase subunit e 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657678" }, "gene_names": [ { "name": "ATP6V0E1", "type": "recommended", "evidence": [ { "id": "A0A4X1U843", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843" } ] }, { "name": "ATP6V0E1", "type": "synonym", "evidence": [ { "id": "XP_005657678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657678" } ] } ], "protein_names": [ { "name": "V-type proton ATPase subunit", "type": "recommended", "evidence": [ { "id": "A0A4X1U843", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843/entry#names_and_taxonomy" } ] }, { "name": "V-type proton ATPase subunit e 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005657678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657678" } ] } ], "function": [ { "annotation": "Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U843", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843#function" }, { "database": "UniProtKB", "id": "PIRNR038097", "url": "https://www.uniprot.org/uniprotkb/PIRNR038097#function" }, { "database": "UniProtKB", "id": "ARBA00045818", "url": "https://www.uniprot.org/uniprotkb/ARBA00045818#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U843", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ATP6V0E1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843", "locus": {} } ], "crossref": [ { "id": "A0A4X1U843", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U843", "database": "AlphaFoldDB", "categories": [] }, { "id": "733646", "url": "https://www.ncbi.nlm.nih.gov/gene/733646", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "7U8O", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7U8O&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7U8P", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7U8P&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7U8Q", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7U8Q&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7U8R", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7U8R&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR008389", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008389", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TDAIWYL", "url": "https://omabrowser.org/oma/group/TDAIWYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1U843", "url": "https://www.orthodb.org/?gene=A0A4X1U843", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12263", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12263", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12263:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12263:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00007u8o", "url": "https://www.rcsb.org/structure/pdb_00007u8o", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007u8p", "url": "https://www.rcsb.org/structure/pdb_00007u8p", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007u8q", "url": "https://www.rcsb.org/structure/pdb_00007u8q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00007u8r", "url": "https://www.rcsb.org/structure/pdb_00007u8r", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7U8O", "url": "https://www.rcsb.org/structure/7U8O", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7U8P", "url": "https://www.rcsb.org/structure/7U8P", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7U8Q", "url": "https://www.rcsb.org/structure/7U8Q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7U8R", "url": "https://www.rcsb.org/structure/7U8R", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF05493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1222556", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1222556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-77387", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77387", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-917977", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917977", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983712", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983712", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005657678", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657678", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1U843", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U843-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBX4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYTGLTVPLIVMSVFWGFVGFLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP", "length": 81, "header": "tr|A0A4X1U843-1|A0A4X1U843_PIG Isoform 1 of V-type proton ATPase subunit OS=Sus scrofa OX=9823 GN=ATP6V0E1 PE=1 SV=1 CANONICAL=A0A4X1U843-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U843-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843/entry#A0A4X1U843-1", "sequence": { "sequence": "MAYTGLTVPLIVMSVFWGFVGFLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP", "length": 81, "header": "tr|A0A4X1U843-1|A0A4X1U843_PIG Isoform 1 of V-type proton ATPase subunit OS=Sus scrofa OX=9823 GN=ATP6V0E1 PE=1 SV=1 CANONICAL=A0A4X1U843-1" }, "locus": { "chromosome": "16", "start_pos": 51260605, "end_pos": 51233567, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061101.2", "url": "https://www.ensembl.org/id/ENSSSCT00000061101.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050892.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050892.1" } ] } }, { "isoform_ac": "A0A8W4FBX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843/entry#A0A8W4FBX4-1", "sequence": { "sequence": "MAYTGLTVPLIVMSVFWGFVGFLVPWFIPKGPNRGWLIAILAQLNPLFGPQLKNETIWYLKYHWP", "length": 65, "header": "tr|A0A8W4FBX4-1|A0A4X1U843_PIG Computationally mapped isoform of V-type proton ATPase subunit OS=Sus scrofa OX=9823 GN=ATP6V0E1 PE=1 SV=1 CANONICAL=A0A4X1U843-1" }, "locus": { "chromosome": "16", "start_pos": 51260605, "end_pos": 51233567, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103822.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103822.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076902.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076902.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U843", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7.", "journal": "Life. Sci Alliance", "date": "2022", "authors": "Tan Yong Zi, Abbas Yazan M, Wu Jing Ze, Wu Di, Keon Kristine A, Hesketh Geoffrey G, Bueler Stephanie A, Gingras Anne-Claude, Robinson Carol V, Grinstein Sergio, Rubinstein John L", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U843", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843" } ], "reference": [ { "type": "PubMed", "id": "35794005", "url": "https://glygen.org/publication/PubMed/35794005" } ] } ], "pathway": [ { "id": "R-SSC-1222556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1222556", "resource": "Reactome", "description": "ROS and RNS production in phagocytes" }, { "id": "R-SSC-77387", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77387", "resource": "Reactome", "description": "Insulin receptor recycling" }, { "id": "R-SSC-917977", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917977", "resource": "Reactome", "description": "Transferrin endocytosis and recycling" }, { "id": "R-SSC-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" }, { "id": "R-SSC-983712", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983712", "resource": "Reactome", "description": "Ion channel transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MX62-1", "protein_name": "V-type proton ATPase subunit", "gene_name": "Atp6v0e1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAYHGLTVPLIVMSVFWGFVGLLVPWFIPKGPNRGVIITMLVTCSICCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP", "length": 81 }, "evidence": [ { "id": "A0A4X1U843", "url": "https://omabrowser.org/oma/group/A0A4X1U843/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P81103-1", "protein_name": "V-type proton ATPase subunit e 1", "gene_name": "ATP6V0E1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAYTGLTVPLIVMSVFWGIVGFLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP", "length": 81 }, "evidence": [ { "id": "A0A4X1U843", "url": "https://omabrowser.org/oma/group/A0A4X1U843/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CQD8-1", "protein_name": "V-type proton ATPase subunit e 1", "gene_name": "Atp6v0e1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAYHGLTVPLIVMSVFWGFVGLLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP", "length": 81 }, "evidence": [ { "id": "A0A4X1U843", "url": "https://omabrowser.org/oma/group/A0A4X1U843/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U843", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "vacuolar proton-transporting V-type ATPase, V0 domain", "id": "GO:0000220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000220", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U843", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843" } ], "pmid": "" }, { "name": "proton-transporting V-type ATPase, V0 domain", "id": "GO:0033179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033179", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U843", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U843", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U843" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U8E2-1", "uniprot_ac": "A0A4X1U8E2", "uniprot_id": "A0A4X1U8E2_PIG", "mass": { "chemical_mass": 26686.0, "monoisotopic_mass": 26686.0 }, "refseq": {}, "gene_names": [ { "name": "VTI1B", "type": "recommended", "evidence": [ { "id": "A0A4X1U8E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ] } ], "protein_names": [ { "name": "Vesicle transport through interaction with t-SNAREs homolog 1B", "type": "recommended", "evidence": [ { "id": "A0A4X1U8E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "VTI1B", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2", "locus": { "chromosome": "7", "start_pos": 91374640, "end_pos": 91413607, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002295", "url": "https://www.ensembl.org/id/ENSSSCG00000002295" } ] } } ], "crossref": [ { "id": "A0A4X1U8E2", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U8E2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15890", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15890", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YRRVMTN", "url": "https://omabrowser.org/oma/group/YRRVMTN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21230", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21230", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21230:SF89", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21230:SF89", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U8E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATSAASSEHFEKLHEIFRGLHEDLRGVPERLLGIAGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRTYRKDLAKLHREVRSTPLTAAPGGRGDMKYGTYAVEDEHMNRLQSQRVLLLQGTDSLNRATQSIERSHRIAAETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLLLSIVILLELAILGGLVYYKFFRRL", "length": 232, "header": "tr|A0A4X1U8E2-1|A0A4X1U8E2_PIG Isoform 1 of Vesicle transport through interaction with t-SNAREs homolog 1B OS=Sus scrofa OX=9823 GN=VTI1B PE=1 SV=1 CANONICAL=A0A4X1U8E2-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U8E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2/entry#A0A4X1U8E2-1", "sequence": { "sequence": "MATSAASSEHFEKLHEIFRGLHEDLRGVPERLLGIAGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRTYRKDLAKLHREVRSTPLTAAPGGRGDMKYGTYAVEDEHMNRLQSQRVLLLQGTDSLNRATQSIERSHRIAAETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLLLSIVILLELAILGGLVYYKFFRRL", "length": 232, "header": "tr|A0A4X1U8E2-1|A0A4X1U8E2_PIG Isoform 1 of Vesicle transport through interaction with t-SNAREs homolog 1B OS=Sus scrofa OX=9823 GN=VTI1B PE=1 SV=1 CANONICAL=A0A4X1U8E2-1" }, "locus": { "chromosome": "7", "start_pos": 91413472, "end_pos": 91386107, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002556.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002556.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002492.2", "url": "https://www.ensembl.org/id/ENSSSCP00000002492.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BUX5-1", "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1B", "gene_name": "VTI1B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAIRGPASSEHLERLHEIFRGLHGELRGVPERLRGGAAEEKKKLIREFDEKQREANETLREMEEELKYAPLPFRNQMMSKIRAYRRDLSMFQREMKNTDLGLGPGSQGDMKYGIFSTENEQSTNLQSQRVLLLQGTESLNRASQSIERSHRIAAETDQIGTDIIEELGEQREQLERTKSRLVNTSENLSKSRKILRSMSRRIATNKLLLSIIIILELAILGGVVYYKFFRSR", "length": 232 }, "evidence": [ { "id": "A0A4X1U8E2", "url": "https://omabrowser.org/oma/group/A0A4X1U8E2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P58200-1", "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1B", "gene_name": "Vti1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATSAASSEHFEKLHEIFRGLLEDLQGVPERLLGTAGTEEKKKLVRDFDEKQQEANETLAEMEEELRYAPLTFRNSMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDLKFGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIAAETDQIGSEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIIVLELAILVGLVYYKFFRHH", "length": 232 }, "evidence": [ { "id": "A0A4X1U8E2", "url": "https://omabrowser.org/oma/group/A0A4X1U8E2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54CK6-1", "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "gene_name": "vti1A", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDVFERTEQNFQHVCNSITRRIKQLPNYGGEKKKIAVREVENDIDEALKFISEMEKLAQNHPQRIKLQTKTKQYHSDIQKYKREVQLAQLQSSNQTNSNPWSNAPDDYQSQYDNQRQHLLQGSNMLDSTSDRLLRTHQISAQSEQIGQNILMDLGKQGEQIRGMRDKLHETDDQIKSARKIMTGIARRLATNKVILSIIILLLMGIIALIICLKWLR", "length": 217 }, "evidence": [ { "id": "A0A4X1U8E2", "url": "https://omabrowser.org/oma/group/A0A4X1U8E2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9SEL5-1", "protein_name": "Vesicle transport v-SNARE 12", "gene_name": "VTI12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSDVFEGYERQYCELSTNLSRKCHSASVLSNGEEKKGKIAEIKSGIDEADVLIRKMDLEARSLQPSAKAVCLSKLREYKSDLNQLKKEFKRVSSADAKPSSREELMESGMADLHAVSADQRGRLAMSVERLDQSSDRIRESRRLMLETEEVGISIVQDLSQQRQTLLHAHNKLHGVDDAIDKSKKVLTAMSRRMTRNKWIITSVIVALVLAIILIISYKLSH", "length": 222 }, "evidence": [ { "id": "A0A4X1U8E2", "url": "https://omabrowser.org/oma/group/A0A4X1U8E2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UEU0-1", "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1B", "gene_name": "VTI1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSAASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLLLSIIILLELAILGGLVYYKFFRSH", "length": 232 }, "evidence": [ { "id": "A0A4X1U8E2", "url": "https://omabrowser.org/oma/group/A0A4X1U8E2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chloride channel inhibitor activity", "id": "GO:0019869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019869", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "regulation of protein localization to plasma membrane", "id": "GO:1903076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903076", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "vesicle fusion with Golgi apparatus", "id": "GO:0048280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048280", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8E2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U8E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8E2" }, { "id": "SM00397", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00397" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-SNARE coiled-coil homology", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 198, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 187, "end_pos": 189 }, { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U8N7-1", "uniprot_ac": "A0A4X1U8N7", "uniprot_id": "A0A4X1U8N7_PIG", "mass": { "chemical_mass": 11534.0, "monoisotopic_mass": 11534.0 }, "refseq": {}, "gene_names": [ { "name": "GAST", "type": "recommended", "evidence": [ { "id": "A0A4X1U8N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7" } ] } ], "protein_names": [ { "name": "Gastrin", "type": "recommended", "evidence": [ { "id": "A0A4X1U8N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8N7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7#function" }, { "database": "UniProtKB", "id": "ARBA00003187", "url": "https://www.uniprot.org/uniprotkb/ARBA00003187#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8N7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GAST", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7", "locus": { "chromosome": "12", "start_pos": 20953202, "end_pos": 20955434, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021910", "url": "https://www.ensembl.org/id/ENSSSCG00000021910" } ] } } ], "crossref": [ { "id": "A0A4X1U8N7", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U8N7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WKPRSQL", "url": "https://omabrowser.org/oma/group/WKPRSQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19309", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19309", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19309:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19309:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00918", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00918", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1U8N7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U8N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRLCAYVLILVLALAACSEASWKPGFQLQDASSGPGANRGKEPHELDRLGPASHHRRQLGLQGPPHLVADLAKKQGPWMEEEEEAYGWMDFGRRSAEEGDQRP", "length": 104, "header": "tr|A0A4X1U8N7-1|A0A4X1U8N7_PIG Isoform 1 of Gastrin OS=Sus scrofa OX=9823 GN=GAST PE=3 SV=1 CANONICAL=A0A4X1U8N7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U8N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7/entry#A0A4X1U8N7-1", "sequence": { "sequence": "MQRLCAYVLILVLALAACSEASWKPGFQLQDASSGPGANRGKEPHELDRLGPASHHRRQLGLQGPPHLVADLAKKQGPWMEEEEEAYGWMDFGRRSAEEGDQRP", "length": 104, "header": "tr|A0A4X1U8N7-1|A0A4X1U8N7_PIG Isoform 1 of Gastrin OS=Sus scrofa OX=9823 GN=GAST PE=3 SV=1 CANONICAL=A0A4X1U8N7-1" }, "locus": { "chromosome": "12", "start_pos": 20953727, "end_pos": 20953291, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025368.2", "url": "https://www.ensembl.org/id/ENSSSCT00000025368.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022312.1", "url": "https://www.ensembl.org/id/ENSSSCP00000022312.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8N7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "G3HLU7-1", "protein_name": "Gastrin", "gene_name": "Gast", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPRLCLCMAILVLALATFSEASWKSHSHLQDASSGPGTSGGLEPNQLDQLRPASPHRRQLGLQGAQHFITDLSKKQRPWMEEEEEAYGWMDFGRRSAEEGDQRN", "length": 104 }, "evidence": [ { "id": "A0A4X1U8N7", "url": "https://omabrowser.org/oma/group/A0A4X1U8N7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P01350-1", "protein_name": "Gastrin", "gene_name": "GAST", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQRLCVYVLIFALALAAFSEASWKPRSQQPDAPLGTGANRDLELPWLEQQGPASHHRRQLGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDFGRRSAEDEN", "length": 101 }, "evidence": [ { "id": "A0A4X1U8N7", "url": "https://omabrowser.org/oma/group/A0A4X1U8N7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P01352-1", "protein_name": "Gastrin", "gene_name": "GAST", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQRLCAHVLILVLALAAFCEASWKPHSHLQDAPVAPGANRGQEPLRMNRLGPASNPRRQLGLQDPPHMVADLSKKQGPWVEEEEAAYGWMDFGRRSAEEGDQHP", "length": 104 }, "evidence": [ { "id": "A0A4X1U8N7", "url": "https://omabrowser.org/oma/group/A0A4X1U8N7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P04563-1", "protein_name": "Gastrin", "gene_name": "Gast", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLCVCMLVLVLALATFSEASWKPRSQLQDASSGPRTNGALEQHQLEKLGPASHHRRQLGPQGPQHFIADLSKKQRPPMEEEEEAYGWMDFGRRSAEEEDQYN", "length": 104 }, "evidence": [ { "id": "A0A4X1U8N7", "url": "https://omabrowser.org/oma/group/A0A4X1U8N7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P48757-1", "protein_name": "Gastrin", "gene_name": "Gast", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRLCVYMLVLVLALATFSEASWKPRSQLQDASSGPGTNEDLEQRQFNKLGSASHHRRQLGPQGPQHFIADLSKKQRPRMEEEEEAYGWMDFGRRSAEEDQ", "length": 101 }, "evidence": [ { "id": "A0A4X1U8N7", "url": "https://omabrowser.org/oma/group/A0A4X1U8N7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8N7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8N7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7" } ], "pmid": "" }, { "name": "response to food", "id": "GO:0032094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032094", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8N7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8N7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1U8N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8N7" }, { "id": "PF00918", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00918" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gastrin/cholecystokinin peptide hormone", "eco_id": "ECO_0000259", "start_pos": 87, "end_pos": 101, "start_aa": "Tyr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1U8P5-1", "uniprot_ac": "A0A4X1U8P5", "uniprot_id": "A0A4X1U8P5_PIG", "mass": { "chemical_mass": 26863.0, "monoisotopic_mass": 26863.0 }, "refseq": {}, "gene_names": [ { "name": "DIABLO", "type": "recommended", "evidence": [ { "id": "A0A4X1U8P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5" } ] } ], "protein_names": [ { "name": "Diablo IAP-binding mitochondrial protein", "type": "recommended", "evidence": [ { "id": "A0A4X1U8P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5/entry#names_and_taxonomy" } ] }, { "name": "Diablo homolog, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A4X1U8P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5/entry#names_and_taxonomy" } ] }, { "name": "Direct IAP-binding protein with low pI", "type": "synonym", "evidence": [ { "id": "A0A4X1U8P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/BRUCE by inhibiting its binding to caspases.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8P5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5#function" }, { "database": "UniProtKB", "id": "ARBA00057426", "url": "https://www.uniprot.org/uniprotkb/ARBA00057426#function" }, { "database": "UniProtKB", "id": "A0A4X1U8R7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8R7#function" }, { "database": "UniProtKB", "id": "A0A5G2QTQ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8P5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DIABLO", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5", "locus": { "chromosome": "14", "start_pos": 30520070, "end_pos": 30498900, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009799", "url": "https://www.ensembl.org/id/ENSSSCG00000009799" } ] } } ], "crossref": [ { "id": "A0A4X1U8P5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1U8P5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009799", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009799", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR009062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WRCCAFF", "url": "https://omabrowser.org/oma/group/WRCCAFF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR32247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32247:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32247:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-111457", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111457", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-111463", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111463", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-111464", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111464", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-111469", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111469", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9627069", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9627069", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1U8P5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U8P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U8R7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1U8R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTQ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QTQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALRSWLSRNVAFFFRYRQCVPVVANLKKRCFSELIRPWHKTVVVGLGVTLCAVPIAQKSEPHSLSNDALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLISLYRQYTSLLGKMNSQEEDEVWQVIIGARVEMTSKQQEYLKLETTWMTAVSLSEMAAEAAYQTGADQASITARSHIQLVKSQVQEVRQLSQKAETKLAEAQTEELRQKTQEEGHESAEPEQEAYLRED", "length": 237, "header": "tr|A0A4X1U8P5-1|A0A4X1U8P5_PIG Isoform 1 of Diablo IAP-binding mitochondrial protein OS=Sus scrofa OX=9823 GN=DIABLO PE=1 SV=1 CANONICAL=A0A4X1U8P5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U8P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5/entry#A0A4X1U8P5-1", "sequence": { "sequence": "MAALRSWLSRNVAFFFRYRQCVPVVANLKKRCFSELIRPWHKTVVVGLGVTLCAVPIAQKSEPHSLSNDALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLISLYRQYTSLLGKMNSQEEDEVWQVIIGARVEMTSKQQEYLKLETTWMTAVSLSEMAAEAAYQTGADQASITARSHIQLVKSQVQEVRQLSQKAETKLAEAQTEELRQKTQEEGHESAEPEQEAYLRED", "length": 237, "header": "tr|A0A4X1U8P5-1|A0A4X1U8P5_PIG Isoform 1 of Diablo IAP-binding mitochondrial protein OS=Sus scrofa OX=9823 GN=DIABLO PE=1 SV=1 CANONICAL=A0A4X1U8P5-1" }, "locus": { "chromosome": "14", "start_pos": 30519251, "end_pos": 30498938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010741.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010741.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010461.3", "url": "https://www.ensembl.org/id/ENSSSCP00000010461.3" } ] } }, { "isoform_ac": "A0A4X1U8R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5/entry#A0A4X1U8R7-1", "sequence": { "sequence": "MAALRSWLSRNVAFFFRYRQCVPVVANLKKRCFSELIRPWHKTVVVGLGVTLCAVPIAQAVYTLISLYRQYTSLLGKMNSQEEDEVWQVIIGARVEMTSKQQEYLKLETTWMTAVSLSEMAAEAAYQTGADQASITARSHIQLVKSQVQEVRQLSQKAETKLAEAQTEELRQKTQEEGHESAEPEQEAYLRED", "length": 193, "header": "tr|A0A4X1U8R7-1|A0A4X1U8R7_PIG Computationally mapped isoform of Diablo IAP-binding mitochondrial protein OS=Sus scrofa OX=9823 GN=DIABLO PE=1 SV=1 CANONICAL=A0A4X1U8P5-1" }, "locus": { "chromosome": "14", "start_pos": 30519251, "end_pos": 30498938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088153.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088153.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070644.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070644.1" } ] } }, { "isoform_ac": "A0A5G2QTQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5/entry#A0A5G2QTQ6-1", "sequence": { "sequence": "MRIMFFTWLKNVCVFQKSEPHSLSNDALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLISLYRQYTSLLGKMNSQEEDEVWQVIIGARVEMTSKQQEYLKLETTWMTAVSLSEMAAEAAYQTGADQASITARSHIQLVKSQVQEVRQLSQKAETKLAEAQTEELRQKTQEEGHESAEPEQEAYLRED", "length": 194, "header": "tr|A0A5G2QTQ6-1|A0A4X1U8P5_PIG Computationally mapped isoform of Diablo IAP-binding mitochondrial protein OS=Sus scrofa OX=9823 GN=DIABLO PE=1 SV=2 CANONICAL=A0A4X1U8P5-1" }, "locus": { "chromosome": "14", "start_pos": 30519251, "end_pos": 30505994, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089140.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089140.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061535.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061535.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QTQ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTQ6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-111457", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111457", "resource": "Reactome", "description": "Release of apoptotic factors from the mitochondria" }, { "id": "R-SSC-111463", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111463", "resource": "Reactome", "description": "SMAC (DIABLO) binds to IAPs" }, { "id": "R-SSC-111464", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111464", "resource": "Reactome", "description": "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" }, { "id": "R-SSC-111469", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111469", "resource": "Reactome", "description": "SMAC, XIAP-regulated apoptotic response" }, { "id": "R-SSC-9627069", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9627069", "resource": "Reactome", "description": "Regulation of the apoptosome activity" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9NR28-1", "protein_name": "Diablo IAP-binding mitochondrial protein", "gene_name": "DIABLO", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIAQKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED", "length": 239 }, "evidence": [ { "id": "A0A4X1U8P5", "url": "https://omabrowser.org/oma/group/A0A4X1U8P5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8P5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8P5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8P5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5" } ], "pmid": "" }, { "name": "CD40 receptor complex", "id": "GO:0035631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035631", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8P5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8P5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5" } ], "pmid": "" }, { "name": "neuron apoptotic process", "id": "GO:0051402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051402", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8P5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to oxidative stress", "id": "GO:0008631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008631", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8P5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway", "id": "GO:0097193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097193", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1U8P5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U8P5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UFB5-1", "uniprot_ac": "A0A4X1UFB5", "uniprot_id": "A0A4X1UFB5_PIG", "mass": { "chemical_mass": 12445.0, "monoisotopic_mass": 12445.0 }, "refseq": {}, "gene_names": [ { "name": "ATP5PF", "type": "recommended", "evidence": [ { "id": "A0A4X1UFB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5" } ] } ], "protein_names": [ { "name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A4X1UFB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5/entry#names_and_taxonomy" } ] }, { "name": "ATPase subunit F6", "type": "synonym", "evidence": [ { "id": "A0A4X1UFB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAD7#function" }, { "database": "UniProtKB", "id": "PIRNR002455", "url": "https://www.uniprot.org/uniprotkb/PIRNR002455#function" }, { "database": "UniProtKB", "id": "A0A4X1UFB5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5#function" } ] }, { "annotation": "Subunit F6, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAD7#function" }, { "database": "UniProtKB", "id": "ARBA00059339", "url": "https://www.uniprot.org/uniprotkb/ARBA00059339#function" }, { "database": "UniProtKB", "id": "A0A4X1UFB5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UFB5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ATP5PF", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5", "locus": { "chromosome": "13", "start_pos": 189278945, "end_pos": 189290229, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000038399", "url": "https://www.ensembl.org/id/ENSSSCG00000038399" } ] } } ], "crossref": [ { "id": "A0A4X1UFB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UFB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RRNIGMS", "url": "https://omabrowser.org/oma/group/RRNIGMS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UFB5", "url": "https://www.orthodb.org/?gene=A0A4X1UFB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12441", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12441", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12441:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12441:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05511", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05511", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-163210", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8949613", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8949613", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UAD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UFB5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UFB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MILQRLFRLSSVIQSAVSVSLRRNIGVTAVAFNKELDPVQKLFVDKIREYRTKRQTSGGPVDAGPEYQQDLDRELFKLKQMYGKADMNTFPNFTFEDPKFEAVEKPQS", "length": 108, "header": "tr|A0A4X1UFB5-1|A0A4X1UFB5_PIG Isoform 1 of ATP synthase peripheral stalk subunit F6, mitochondrial OS=Sus scrofa OX=9823 GN=ATP5PF PE=3 SV=1 CANONICAL=A0A4X1UFB5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5/entry#A0A4X1UAD7-1", "sequence": { "sequence": "MPCNGGITMILQRLFRLSSVIQSAVSVSLRRNIGVTAVAFNKELDPVQKLFVDKIREYRTKRQTSGGPVDAGPEYQQDLDRELFKLKQMYGKADMNTFPNFTFEDPKFEAVEKPQS", "length": 116, "header": "tr|A0A4X1UAD7-1|A0A4X1UFB5_PIG Computationally mapped isoform of ATP synthase peripheral stalk subunit F6, mitochondrial OS=Sus scrofa OX=9823 GN=ATP5PF PE=3 SV=1 CANONICAL=A0A4X1UFB5-1" }, "locus": { "chromosome": "13", "start_pos": 189289523, "end_pos": 189281523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066019.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066019.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051036.2", "url": "https://www.ensembl.org/id/ENSSSCP00000051036.2" } ] } }, { "isoform_ac": "A0A4X1UFB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5/entry#A0A4X1UFB5-1", "sequence": { "sequence": "MILQRLFRLSSVIQSAVSVSLRRNIGVTAVAFNKELDPVQKLFVDKIREYRTKRQTSGGPVDAGPEYQQDLDRELFKLKQMYGKADMNTFPNFTFEDPKFEAVEKPQS", "length": 108, "header": "tr|A0A4X1UFB5-1|A0A4X1UFB5_PIG Isoform 1 of ATP synthase peripheral stalk subunit F6, mitochondrial OS=Sus scrofa OX=9823 GN=ATP5PF PE=3 SV=1 CANONICAL=A0A4X1UFB5-1" }, "locus": { "chromosome": "13", "start_pos": 189285290, "end_pos": 189281523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045597.2", "url": "https://www.ensembl.org/id/ENSSSCT00000045597.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041752.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041752.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAD7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAD7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-163210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163210", "resource": "Reactome", "description": "Formation of ATP by chemiosmotic coupling" }, { "id": "R-SSC-8949613", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8949613", "resource": "Reactome", "description": "Cristae formation" }, { "id": "R-SSC-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HQF5-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MILQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPIQKLFVDKIREYKSKRQTSGGPVDTGPEYHQELERELFKLKQMFGKGDMDTFPTFKFEDPKFEVFDKPQS", "length": 108 }, "evidence": [ { "id": "A0A4X1UFB5", "url": "https://omabrowser.org/oma/group/A0A4X1UFB5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P18859-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ATP5PF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MILQRLFRFSSVIRSAVSVHLRRNIGVTAVAFNKELDPIQKLFVDKIREYKSKRQTSGGPVDASSEYQQELERELFKLKQMFGNADMNTFPTFKFEDPKFEVIEKPQA", "length": 108 }, "evidence": [ { "id": "A0A4X1UFB5", "url": "https://omabrowser.org/oma/group/A0A4X1UFB5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97450-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQRIFRLSSVLRSAVSVHLKRNIGVTAVAFNKELDPVQKLFVDKIREYKSKRQASGGPVDIGPEYQQDLDRELYKLKQMYGKGEMDTFPTFKFDDPKFEVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A4X1UFB5", "url": "https://omabrowser.org/oma/group/A0A4X1UFB5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UFB5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5" } ], "pmid": "" }, { "name": "proton-transporting ATP synthase complex", "id": "GO:0045259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045259", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UFB5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proton motive force-driven mitochondrial ATP synthesis", "id": "GO:0042776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042776", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UFB5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5" } ], "pmid": "" }, { "name": "proton motive force-driven ATP synthesis", "id": "GO:0015986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015986", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UFB5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "proton-transporting ATP synthase activity, rotational mechanism", "id": "GO:0046933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046933", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UFB5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5" } ], "pmid": "" }, { "name": "proton transmembrane transporter activity", "id": "GO:0015078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015078", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UFB5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UFB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UAH0-1", "uniprot_ac": "A0A4X1UAH0", "uniprot_id": "A0A4X1UAH0_PIG", "mass": { "chemical_mass": 17907.0, "monoisotopic_mass": 17907.0 }, "refseq": { "ac": "XP_020922077", "name": "transcription factor MafG", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922077" }, "gene_names": [ { "name": "MAFG", "type": "recommended", "evidence": [ { "id": "A0A4X1UAH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" } ] }, { "name": "MAFG", "type": "synonym", "evidence": [ { "id": "XP_020922077", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922077" } ] } ], "protein_names": [ { "name": "Transcription factor MafG", "type": "recommended", "evidence": [ { "id": "A0A4X1UAH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0/entry#names_and_taxonomy" } ] }, { "name": "V-maf musculoaponeurotic fibrosarcoma oncogene homolog G", "type": "synonym", "evidence": [ { "id": "A0A4X1UAH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0/entry#names_and_taxonomy" } ] }, { "name": "transcription factor MafG", "type": "synonym", "evidence": [ { "id": "XP_020922077", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922077" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MAFG", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0", "locus": { "chromosome": "12", "start_pos": 1074688, "end_pos": 1071632, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000035253", "url": "https://www.ensembl.org/id/ENSSSCG00000035253" } ] } } ], "crossref": [ { "id": "A0A4X1UAH0", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UAH0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14717", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14717", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110255931", "url": "https://www.ncbi.nlm.nih.gov/gene/110255931", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024874", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024874", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110255931", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255931", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QHSRYRF", "url": "https://omabrowser.org/oma/group/QHSRYRF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UAH0", "url": "https://www.orthodb.org/?gene=A0A4X1UAH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10129:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10129:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03131", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03131", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020922077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922077", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1UAH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UAH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIIQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQNFARTVARSPVAPARGPLAASLGPLVPGKVAATSVITIVKSKTDARS", "length": 162, "header": "tr|A0A4X1UAH0-1|A0A4X1UAH0_PIG Isoform 1 of Transcription factor MafG OS=Sus scrofa OX=9823 GN=MAFG PE=3 SV=1 CANONICAL=A0A4X1UAH0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UAH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0/entry#A0A4X1UAH0-1", "sequence": { "sequence": "MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIIQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQNFARTVARSPVAPARGPLAASLGPLVPGKVAATSVITIVKSKTDARS", "length": 162, "header": "tr|A0A4X1UAH0-1|A0A4X1UAH0_PIG Isoform 1 of Transcription factor MafG OS=Sus scrofa OX=9823 GN=MAFG PE=3 SV=1 CANONICAL=A0A4X1UAH0-1" }, "locus": { "chromosome": "12", "start_pos": 1073725, "end_pos": 1073145, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041350.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041350.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053191.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053191.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110255931", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255931", "resource": "KEGG Pathway" }, { "id": "R-SSC-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JNS4-1", "protein_name": "Transcription factor MafG", "gene_name": "Mafg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRSLGAPADAGPGRGAQAGSRAVRAGGRARSGRRRSGQEPGVVFKFIGPSACSLCPRVMTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIIQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQNFARTVARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS", "length": 220 }, "evidence": [ { "id": "A0A4X1UAH0", "url": "https://omabrowser.org/oma/group/A0A4X1UAH0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A5PJV0-1", "protein_name": "Transcription factor MafG", "gene_name": "MAFG", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIIQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQNFARTVARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS", "length": 162 }, "evidence": [ { "id": "A0A4X1UAH0", "url": "https://omabrowser.org/oma/group/A0A4X1UAH0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O15525-1", "protein_name": "Transcription factor MafG", "gene_name": "MAFG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFARTVARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS", "length": 162 }, "evidence": [ { "id": "A0A4X1UAH0", "url": "https://omabrowser.org/oma/group/A0A4X1UAH0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O54790-1", "protein_name": "Transcription factor MafG", "gene_name": "Mafg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIIQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQNFARTVARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS", "length": 162 }, "evidence": [ { "id": "A0A4X1UAH0", "url": "https://omabrowser.org/oma/group/A0A4X1UAH0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q76MX4-1", "protein_name": "Transcription factor MafG", "gene_name": "Mafg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPNKGNKALKVSGEAGLGVCWAGHSYSALTPCAVPLQVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIIQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQNFARTVARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS", "length": 189 }, "evidence": [ { "id": "A0A4X1UAH0", "url": "https://omabrowser.org/oma/group/A0A4X1UAH0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q90889-1", "protein_name": "Transcription factor MafG", "gene_name": "MAFG", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIIQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKMELDALRSKYEALQNFARTVARSPVTPVRGPLTSSMGPLVPGKVATTSVITIVKSKTDARS", "length": 162 }, "evidence": [ { "id": "A0A4X1UAH0", "url": "https://omabrowser.org/oma/group/A0A4X1UAH0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of epidermal cell differentiation", "id": "GO:0045604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045604", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAH0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UAH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAH0" }, { "id": "PS50217", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BZIP", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 114, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UAI6-1", "uniprot_ac": "A0A4X1UAI6", "uniprot_id": "A0A4X1UAI6_PIG", "mass": { "chemical_mass": 14122.0, "monoisotopic_mass": 14122.0 }, "refseq": {}, "gene_names": [ { "name": "H2BL1", "type": "recommended", "evidence": [ { "id": "A0A4X1UAI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6" } ] } ], "protein_names": [ { "name": "H2B.L histone variant 1", "type": "synonym", "evidence": [ { "id": "A0A4X1UAI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "H2BL1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6", "locus": {} } ], "crossref": [ { "id": "A0A4X1UAI6", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UAI6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22910", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22910", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519930", "url": "https://www.ncbi.nlm.nih.gov/gene/100519930", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000558", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519930", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519930", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MYFRNRC", "url": "https://omabrowser.org/oma/group/MYFRNRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UAI6", "url": "https://www.orthodb.org/?gene=A0A4X1UAI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00125", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1UAI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UAI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARYITKKNRCSRGHRHPNSRKKTCSSTECGRRNYSLYVNRVLKEVVPQSGISSRTLDMMNTVINDIFERISMEASNLMYFRNRCTLTPEDVQKAVYLLLPRKLAKHAVAFGSDAVHRYVHS", "length": 122, "header": "tr|A0A4X1UAI6-1|A0A4X1UAI6_PIG Isoform 1 of H2B.L histone variant 1 OS=Sus scrofa OX=9823 GN=H2BL1 PE=1 SV=1 CANONICAL=A0A4X1UAI6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UAI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6/entry#A0A4X1UAI6-1", "sequence": { "sequence": "MARYITKKNRCSRGHRHPNSRKKTCSSTECGRRNYSLYVNRVLKEVVPQSGISSRTLDMMNTVINDIFERISMEASNLMYFRNRCTLTPEDVQKAVYLLLPRKLAKHAVAFGSDAVHRYVHS", "length": 122, "header": "tr|A0A4X1UAI6-1|A0A4X1UAI6_PIG Isoform 1 of H2B.L histone variant 1 OS=Sus scrofa OX=9823 GN=H2BL1 PE=1 SV=1 CANONICAL=A0A4X1UAI6-1" }, "locus": { "chromosome": "16", "start_pos": 49001274, "end_pos": 49000909, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018487.3", "url": "https://www.ensembl.org/id/ENSSSCT00000018487.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017987.2", "url": "https://www.ensembl.org/id/ENSSSCP00000017987.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519930", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519930", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3IP44-1", "protein_name": "Histone H2B subacrosomal variant", "gene_name": "LOC100752003", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKSIIKRYQFVKRRQRRAFRKRYSSINFGQRNYSLYISRVLKEVVPMRGLSSNTVDIMNTLINDLFERIATEACQLMYFRKRCTLTLEDIQKAVYLLVPKKLAKSAVTFGSKAVHRFIHS", "length": 121 }, "evidence": [ { "id": "A0A4X1UAI6", "url": "https://omabrowser.org/oma/group/A0A4X1UAI6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0R7V6-1", "protein_name": "H2B.L histone variant 1", "gene_name": "H2bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKPILKRYRYIKGHLRPLYRKHLRCSSIHFGHGNYSLYINRVLKEVVPKRGISSHTVDIMNLMINDIFERIATEACQRMNLRKRCTLTSEDIQKAVYMLMPKKLAKLAVTFGSKAVHRFIHS", "length": 123 }, "evidence": [ { "id": "A0A4X1UAI6", "url": "https://omabrowser.org/oma/group/A0A4X1UAI6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WNR4-1", "protein_name": "Histone H2B subacrosomal variant", "gene_name": "SUBH2BV", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARNVTKRNKRCRGHQKAIYKKKSHSSSESGLRNYSLYINRVLKEVVPQKGISSRTIDIINTMINDMFERISTEACNLMYYRKRCTLTPEDIEKAVYLLLPEKLAKYAVAFGKEAVQRYVRS", "length": 122 }, "evidence": [ { "id": "A0A4X1UAI6", "url": "https://omabrowser.org/oma/group/A0A4X1UAI6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D9Z7-1", "protein_name": "Histone H2B variant L1", "gene_name": "H2bl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKPTFKRQCYIKRHLRPLYRKHSRCSSINLGHGNYSLYINRVLKEVVPNRGISSYSVDIMNILINDIFERIATEACQQMFLRKRCTLTPGDIQQAVHLLLPKKLATLAVTFGSKAVHRFIHS", "length": 123 }, "evidence": [ { "id": "A0A4X1UAI6", "url": "https://omabrowser.org/oma/group/A0A4X1UAI6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAI6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UAI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAI6" }, { "id": "PF00125", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Core Histone H2A/H2B/H3", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 98, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UAX1-1", "uniprot_ac": "A0A4X1UAX1", "uniprot_id": "A0A4X1UAX1_PIG", "mass": { "chemical_mass": 26133.0, "monoisotopic_mass": 26133.0 }, "refseq": { "ac": "XP_003134092", "name": "vesicle transport protein SEC20", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134092" }, "gene_names": [ { "name": "BNIP1", "type": "recommended", "evidence": [ { "id": "A0A4X1UAX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ] }, { "name": "BNIP1", "type": "synonym", "evidence": [ { "id": "XP_003134092", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134092" } ] } ], "protein_names": [ { "name": "BCL2 interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A4X1UAX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1/entry#names_and_taxonomy" } ] }, { "name": "vesicle transport protein SEC20", "type": "synonym", "evidence": [ { "id": "XP_003134092", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134092" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BNIP1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1", "locus": { "chromosome": "16", "start_pos": 51126926, "end_pos": 51140394, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016985", "url": "https://www.ensembl.org/id/ENSSSCG00000016985" } ] } } ], "crossref": [ { "id": "A0A4X1UAX1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UAX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15865", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15865", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521935", "url": "https://www.ncbi.nlm.nih.gov/gene/100521935", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521935", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521935", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TEVDTHR", "url": "https://omabrowser.org/oma/group/TEVDTHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UAX1", "url": "https://www.orthodb.org/?gene=A0A4X1UAX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12825", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12825", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12825:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12825:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003134092", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134092", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UAX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UAX6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UAX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQELEQSAKEQDKESEKQILLQEVENHKKQMLSNQTSWRKANLACKIAIDNLEKAELLQGGDLLRQRKTAKESLAQTSSTITESLMGISRMMSQQVQQSEEAMQTLVNSSRTILDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL", "length": 228, "header": "tr|A0A4X1UAX1-1|A0A4X1UAX1_PIG Isoform 1 of BCL2 interacting protein 1 OS=Sus scrofa OX=9823 GN=BNIP1 PE=1 SV=1 CANONICAL=A0A4X1UAX1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UAX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1/entry#A0A4X1UAX1-1", "sequence": { "sequence": "MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQELEQSAKEQDKESEKQILLQEVENHKKQMLSNQTSWRKANLACKIAIDNLEKAELLQGGDLLRQRKTAKESLAQTSSTITESLMGISRMMSQQVQQSEEAMQTLVNSSRTILDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL", "length": 228, "header": "tr|A0A4X1UAX1-1|A0A4X1UAX1_PIG Isoform 1 of BCL2 interacting protein 1 OS=Sus scrofa OX=9823 GN=BNIP1 PE=1 SV=1 CANONICAL=A0A4X1UAX1-1" }, "locus": { "chromosome": "16", "start_pos": 51140114, "end_pos": 51127330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018495.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018495.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000017995.2", "url": "https://www.ensembl.org/id/ENSSSCP00000017995.2" } ] } }, { "isoform_ac": "A0A4X1UAX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1/entry#A0A4X1UAX6-1", "sequence": { "sequence": "MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQELEQSAKEQDKESEKQILLQEVENHKKQMLRKTAKESLAQTSSTITESLMGISRMMSQQVQQSEEAMQTLVNSSRTILDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL", "length": 194, "header": "tr|A0A4X1UAX6-1|A0A4X1UAX6_PIG Computationally mapped isoform of BCL2 interacting protein 1 OS=Sus scrofa OX=9823 GN=BNIP1 PE=1 SV=1 CANONICAL=A0A4X1UAX1-1" }, "locus": { "chromosome": "16", "start_pos": 51140114, "end_pos": 51127330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082768.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082768.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073574.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073574.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521935", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521935", "resource": "KEGG Pathway" }, { "id": "R-SSC-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y325-1", "protein_name": "BCL2 interacting protein 1", "gene_name": "BNIP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAAATGSVPVRVCHQEIVKFDLEIKAAVQDIRDCPGPLSALTELNAAVKEKFRHLRGRIQELEQMAREQDKESEKQALLQEVENHKKQMLSNQAAWRKANLACKIAIDNSEKDQLLQGRDSLRQRKTTKESLAESASNITESLMSISRMMSQQVQQSEETVQTLANSSRTILEANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYILKKRLFPFL", "length": 231 }, "evidence": [ { "id": "A0A4X1UAX1", "url": "https://omabrowser.org/oma/group/A0A4X1UAX1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3H9Q4-1", "protein_name": "Vesicle transport protein SEC20 isoform X1", "gene_name": "Bnip1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSELTELNTKVKEKFQQLRCRIQELEQSAREQDKESDKQLLLQEVENHKKQMLSNQTSWRKANLTCKIAIDNLEKAELMQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMSQQVQQSEEAMQTLVSSSRTLLDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL", "length": 228 }, "evidence": [ { "id": "A0A4X1UAX1", "url": "https://omabrowser.org/oma/group/A0A4X1UAX1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q12981-4", "protein_name": "Vesicle transport protein SEC20", "gene_name": "BNIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL", "length": 228 }, "evidence": [ { "id": "A0A4X1UAX1", "url": "https://omabrowser.org/oma/group/A0A4X1UAX1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VNI9-1", "protein_name": "Secretory 20, isoform B", "gene_name": "Sec20", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDKDAFTLQAIRQDLIDNNLQAKAIIHDILNSRTSIAELEELNEAGRSKLSAIRKSIERLDDWARDTADSALANEVDDHRDQFSKTLQAFRKANVSTMLEIEKANREELMAITGESELRQRTTTRARHNQGSLVSQENDVTEKMLAISRHLSETTQKSAITLETLVASSQNVEATSDELHHTAGSISMSGKLLKKYGRRECTDKMLLFFAFSLFLACVFYIVQKRLF", "length": 227 }, "evidence": [ { "id": "A0A4X1UAX1", "url": "https://omabrowser.org/oma/group/A0A4X1UAX1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "pmid": "" }, { "name": "endoplasmic reticulum organization", "id": "GO:0007029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007029", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane fusion", "id": "GO:0016320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016320", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "pmid": "" }, { "name": "apoptotic process in response to mitochondrial fragmentation", "id": "GO:0140208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140208", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "pmid": "" }, { "name": "calcium-induced calcium release activity", "id": "GO:0048763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048763", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UAX1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UAX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UAX1" }, { "id": "PF03908", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sec20 C-terminal", "eco_id": "ECO_0000259", "start_pos": 134, "end_pos": 224, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UBY9-1", "uniprot_ac": "A0A4X1UBY9", "uniprot_id": "A0A4X1UBY9_PIG", "mass": { "chemical_mass": 71809.0, "monoisotopic_mass": 71809.0 }, "refseq": {}, "gene_names": [ { "name": "TMCC1", "type": "recommended", "evidence": [ { "id": "A0A4X1UBY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ] } ], "protein_names": [ { "name": "Transmembrane and coiled-coil domain family 1", "type": "synonym", "evidence": [ { "id": "A0A4X1UBY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMCC1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9", "locus": { "chromosome": "13", "start_pos": 69036428, "end_pos": 69290098, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011593", "url": "https://www.ensembl.org/id/ENSSSCG00000011593" } ] } } ], "crossref": [ { "id": "IPR019394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR17613", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17613", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17613:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17613:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10267", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10267", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UBY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1XYX5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XYX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1XYX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XYX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPSGSEQLFEDPDPGGKSQDAEARKQTESEQKLSKMTHNALENINVIGQGLKHLFQHQRRRSSVSPHDVQQIQADPEPEIDLEGQNACAEIDGVPTHPTALNRVLQQIRVPPKMKRGTSLHSRRGKPEAPKGSPQINRKSGQEMATVMQSGRPRSSSTTDAPTSSTVMEIACAAAAAACLPGDEAPAERIERLEVSSLAQTSSAVASSTDGSLHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGLSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDGGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQALQEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVVFIAFLWKHWDALFSYVERFFSSPR", "length": 651, "header": "tr|A0A4X1UBY9-1|A0A4X1UBY9_PIG Isoform 1 of Transmembrane and coiled-coil domain family 1 OS=Sus scrofa OX=9823 GN=TMCC1 PE=3 SV=1 CANONICAL=A0A4X1UBY9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UBY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9/entry#A0A4X1UBY9-1", "sequence": { "sequence": "MEPSGSEQLFEDPDPGGKSQDAEARKQTESEQKLSKMTHNALENINVIGQGLKHLFQHQRRRSSVSPHDVQQIQADPEPEIDLEGQNACAEIDGVPTHPTALNRVLQQIRVPPKMKRGTSLHSRRGKPEAPKGSPQINRKSGQEMATVMQSGRPRSSSTTDAPTSSTVMEIACAAAAAACLPGDEAPAERIERLEVSSLAQTSSAVASSTDGSLHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGLSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDGGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQALQEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVVFIAFLWKHWDALFSYVERFFSSPR", "length": 651, "header": "tr|A0A4X1UBY9-1|A0A4X1UBY9_PIG Isoform 1 of Transmembrane and coiled-coil domain family 1 OS=Sus scrofa OX=9823 GN=TMCC1 PE=3 SV=1 CANONICAL=A0A4X1UBY9-1" }, "locus": { "chromosome": "13", "start_pos": 69224061, "end_pos": 69040097, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048493.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048493.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055581.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055581.1" } ] } }, { "isoform_ac": "A0A8D1XYX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9/entry#A0A8D1XYX5-1", "sequence": { "sequence": "MEPSGSEQLFEDPDPGGKSQDAEARKQTESEQKLSKMTHNALENINVIGQGLKHLFQHQRRRSSVSPHDVQQIQADPEPEIDLEGQNACAEIDGVPTHPTALNRVLQQIRVPPKMKRGTSLHSRRGKPEAPKGSPQINRKSGQEMATVMQSGRPRSSSTTDAPTSSTVMEIACAAAAAACLPGDEAPAERLPFSLNKWDE", "length": 200, "header": "tr|A0A8D1XYX5-1|A0A4X1UBY9_PIG Computationally mapped isoform of Transmembrane and coiled-coil domain family 1 OS=Sus scrofa OX=9823 GN=TMCC1 PE=3 SV=1 CANONICAL=A0A4X1UBY9-1" }, "locus": { "chromosome": "13", "start_pos": 69224061, "end_pos": 69223346, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012689.4", "url": "https://www.ensembl.org/id/ENSSSCT00000012689.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000012356.4", "url": "https://www.ensembl.org/id/ENSSSCP00000012356.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1XYX5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XYX5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ], "pmid": "" }, { "name": "endoplasmic reticulum-endosome membrane contact site", "id": "GO:0140284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140284", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ], "pmid": "" }, { "name": "endoplasmic reticulum organization", "id": "GO:0007029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007029", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ], "pmid": "" }, { "name": "membrane fission", "id": "GO:0090148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090148", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ], "pmid": "" }, { "name": "endosome membrane tubulation", "id": "GO:0097750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097750", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ], "pmid": "" }, { "name": "endosome fission", "id": "GO:0140285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140285", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UBY9", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UBY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 432, "end_pos": 434 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 617, "end_pos": 619 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UC55-1", "uniprot_ac": "A0A4X1UC55", "uniprot_id": "A0A4X1UC55_PIG", "mass": { "chemical_mass": 27390.0, "monoisotopic_mass": 27390.0 }, "refseq": { "ac": "XP_020940339", "name": "ferritin, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940339" }, "gene_names": [ { "name": "FTMT", "type": "recommended", "evidence": [ { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" } ] }, { "name": "FTMT", "type": "synonym", "evidence": [ { "id": "XP_020940339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940339" } ] } ], "protein_names": [ { "name": "Ferritin", "type": "recommended", "evidence": [ { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55/entry#names_and_taxonomy" } ] }, { "name": "ferritin, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_020940339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940339" } ] } ], "function": [ { "annotation": "Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC55", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55#function" }, { "database": "UniProtKB", "id": "RU361145", "url": "https://www.uniprot.org/uniprotkb/RU361145#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC55", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FTMT", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55", "locus": { "chromosome": "2", "start_pos": 125393122, "end_pos": 125392394, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014231", "url": "https://www.ensembl.org/id/ENSSSCG00000014231" } ] } } ], "crossref": [ { "id": "A0A4X1UC55", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UC55", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01056", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01056", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524926", "url": "https://www.ncbi.nlm.nih.gov/gene/100524926", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524926", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524926", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NWESGLH", "url": "https://omabrowser.org/oma/group/NWESGLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UC55", "url": "https://www.orthodb.org/?gene=A0A4X1UC55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11431", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11431", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11431:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11431:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-917937", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917937", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020940339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1UC55", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UC55-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPSFLFLSKHISTSLVSLRSACLCFALPPRCLPGRPWGHQPAALSRPLAAVTYCRGPAGPSCAPSRVRQNFYADSEAAINRQINLELYASYVYLSMAYYFSRDDVALHNFARYFLRQSREETEHAEKLMRLQNQRGGQICLQDIKKPDQDNWKSGLNAMECALLLEKNVNQSLLELHTLASDKGDPHLCDFLETHYLNEQVKSIKELGDHVHNLIKMGAPDSGLAEYLFDKHTLGNENNQH", "length": 242, "header": "tr|A0A4X1UC55-1|A0A4X1UC55_PIG Isoform 1 of Ferritin OS=Sus scrofa OX=9823 GN=FTMT PE=3 SV=1 CANONICAL=A0A4X1UC55-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UC55-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55/entry#A0A4X1UC55-1", "sequence": { "sequence": "MLPSFLFLSKHISTSLVSLRSACLCFALPPRCLPGRPWGHQPAALSRPLAAVTYCRGPAGPSCAPSRVRQNFYADSEAAINRQINLELYASYVYLSMAYYFSRDDVALHNFARYFLRQSREETEHAEKLMRLQNQRGGQICLQDIKKPDQDNWKSGLNAMECALLLEKNVNQSLLELHTLASDKGDPHLCDFLETHYLNEQVKSIKELGDHVHNLIKMGAPDSGLAEYLFDKHTLGNENNQH", "length": 242, "header": "tr|A0A4X1UC55-1|A0A4X1UC55_PIG Isoform 1 of Ferritin OS=Sus scrofa OX=9823 GN=FTMT PE=3 SV=1 CANONICAL=A0A4X1UC55-1" }, "locus": { "chromosome": "2", "start_pos": 125393119, "end_pos": 125392394, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015549.3", "url": "https://www.ensembl.org/id/ENSSSCT00000015549.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015137.2", "url": "https://www.ensembl.org/id/ENSSSCP00000015137.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC55", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524926", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524926", "resource": "KEGG Pathway" }, { "id": "R-SSC-917937", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917937", "resource": "Reactome", "description": "Iron uptake and transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC55", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC55", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC55", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC55", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC55", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC55", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" } ], "pmid": "" }, { "name": "ferroxidase activity", "id": "GO:0004322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004322", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC55", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" } ], "pmid": "" }, { "name": "ferric iron binding", "id": "GO:0008199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008199", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UC55", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" }, { "id": "PS50905", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50905" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ferritin-like diiron", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 219, "start_aa": "Gln", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55#function" }, { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" }, { "id": "PIRSR601519-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601519-1" } ], "binding_site_uniprot": 122, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 122, "end_pos": 122, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55#function" }, { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" }, { "id": "PIRSR601519-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601519-1" } ], "binding_site_uniprot": 125, "amino_acid": "His", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 125, "end_pos": 125, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55#function" }, { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" }, { "id": "PIRSR601519-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601519-1" } ], "binding_site_uniprot": 167, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 167, "end_pos": 167, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55#function" }, { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" }, { "id": "PIRSR601519-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601519-1" } ], "binding_site_uniprot": 201, "amino_acid": "Gln", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 201, "end_pos": 201, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55#function" }, { "id": "A0A4X1UC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UC55" }, { "id": "PIRSR601519-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601519-1" } ], "binding_site_uniprot": 87, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 87, "end_pos": 87, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UCV8-1", "uniprot_ac": "A0A4X1UCV8", "uniprot_id": "A0A4X1UCV8_PIG", "mass": { "chemical_mass": 26165.0, "monoisotopic_mass": 26165.0 }, "refseq": {}, "gene_names": [ { "name": "CLDN16", "type": "recommended", "evidence": [ { "id": "A0A4X1UCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8" } ] } ], "protein_names": [ { "name": "Claudin", "type": "recommended", "evidence": [ { "id": "A0A4X1UCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8#function" }, { "database": "UniProtKB", "id": "RU060637", "url": "https://www.uniprot.org/uniprotkb/RU060637#function" } ] }, { "annotation": "Forms paracellular channels: coassembles with CLDN19 into tight junction strands with cation-selective channels through the strands, conveying epithelial permeability in a process known as paracellular tight junction permeability. Involved in the maintenance of ion gradients along the nephron. In the thick ascending limb (TAL) of Henle's loop, facilitates sodium paracellular permeability from the interstitial compartment to the lumen, contributing to the lumen-positive transepithelial potential that drives paracellular magnesium and calcium reabsorption.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8#function" }, { "database": "UniProtKB", "id": "ARBA00058984", "url": "https://www.uniprot.org/uniprotkb/ARBA00058984#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CLDN16", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8", "locus": { "chromosome": "13", "start_pos": 127830717, "end_pos": 127808599, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000024788", "url": "https://www.ensembl.org/id/ENSSSCG00000024788" } ] } } ], "crossref": [ { "id": "A0A4X1UCV8", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UCV8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29827", "url": "https://www.rhea-db.org/rhea/29827", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78547", "url": "https://www.rhea-db.org/rhea/78547", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78551", "url": "https://www.rhea-db.org/rhea/78551", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78555", "url": "https://www.rhea-db.org/rhea/78555", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UCV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRDLLQYVACFFALFSTGFLVVATWTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSILAEHPLKLVVTRALMITADVLAGFGFITLLLGLDCVKFLPDEPYIKVRICFVAGTTLLIAGAPGIIGSVWYAVDVYVERTSLILHNIFLGIQYKFGWSCWLGMAGSLGCFLAGAVLTCCLYLFKDVGLERNYPYSMRKAYSTTAVSMAKSYVAPRTQTAKMYAVDTRV", "length": 235, "header": "tr|A0A4X1UCV8-1|A0A4X1UCV8_PIG Isoform 1 of Claudin OS=Sus scrofa OX=9823 GN=CLDN16 PE=3 SV=1 CANONICAL=A0A4X1UCV8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UCV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8/entry#A0A4X1UCV8-1", "sequence": { "sequence": "MRDLLQYVACFFALFSTGFLVVATWTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSILAEHPLKLVVTRALMITADVLAGFGFITLLLGLDCVKFLPDEPYIKVRICFVAGTTLLIAGAPGIIGSVWYAVDVYVERTSLILHNIFLGIQYKFGWSCWLGMAGSLGCFLAGAVLTCCLYLFKDVGLERNYPYSMRKAYSTTAVSMAKSYVAPRTQTAKMYAVDTRV", "length": 235, "header": "tr|A0A4X1UCV8-1|A0A4X1UCV8_PIG Isoform 1 of Claudin OS=Sus scrofa OX=9823 GN=CLDN16 PE=3 SV=1 CANONICAL=A0A4X1UCV8-1" }, "locus": { "chromosome": "13", "start_pos": 127829922, "end_pos": 127808840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045531.2", "url": "https://www.ensembl.org/id/ENSSSCT00000045531.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036896.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036896.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8" } ], "pmid": "" }, { "name": "renal absorption", "id": "GO:0070293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070293", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8" } ], "pmid": "" }, { "name": "paracellular transport", "id": "GO:0160184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160184", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8" } ], "pmid": "" }, { "name": "paracellular tight junction channel activity", "id": "GO:0160187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160187", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UCV8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UCV8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] }, { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] }, { "id": "29827", "name": "", "equation": "Mg(2+)(in) = Mg(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29827", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29827" } ] }, { "id": "34963", "name": "", "equation": "Na(+)(in) = Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34963" } ] }, { "id": "78547", "name": "", "equation": "Rb(+)(in) = Rb(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78547", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78547" } ] }, { "id": "78551", "name": "", "equation": "Li(+)(in) = Li(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78551", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78551" } ] }, { "id": "78555", "name": "", "equation": "Cs(+)(in) = Cs(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78555", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78555" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UD94-1", "uniprot_ac": "A0A4X1UD94", "uniprot_id": "A0A4X1UD94_PIG", "mass": { "chemical_mass": 34984.0, "monoisotopic_mass": 34984.0 }, "refseq": { "ac": "XP_020937352", "name": "olfactory receptor 4A47-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937352" }, "gene_names": [ { "name": "LOC110258434", "type": "recommended", "evidence": [ { "id": "A0A4X1UD94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94" } ] }, { "name": "LOC110258434", "type": "synonym", "evidence": [ { "id": "XP_020937352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937352" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A4X1UD94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4A47-like", "type": "synonym", "evidence": [ { "id": "XP_020937352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937352" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UD94", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UD94", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110258434", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94", "locus": {} } ], "crossref": [ { "id": "A0A4X1UD94", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UD94", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110258434", "url": "https://www.ncbi.nlm.nih.gov/gene/110258434", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110258434", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258434", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FAPFIFM", "url": "https://omabrowser.org/oma/group/FAPFIFM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UD94", "url": "https://www.orthodb.org/?gene=A0A4X1UD94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020937352", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937352", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1UD94", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UD94-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRNNVTFFILLGLTQNPKEQKVLFFIFLLFYILTVVGNLLIVVTITVSKTLNSPMYFFLASLSFIDLIYSSSITPRLILDLLFRDNTISFESCMTQLFTEHFFAGSEISLLLVMAYDRYVAICKPLHYLVIMRQRVCVVLLVLSCIGGFLHSIIQLSTIYGLPFCGPNVIDHFICDMFPLLKLVCTDTYVTGILVVANGGLMCIILFLLLLISYGVILHSLKNLSQAGRQKAIQTCGSHITVVVCFFVPCIFINARPAKTFPIDKSLSIFYTVISPMLNPLIYSLRNSELTNAMKKLWRKSYYIKW", "length": 308, "header": "tr|A0A4X1UD94-1|A0A4X1UD94_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258434 PE=3 SV=1 CANONICAL=A0A4X1UD94-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UD94-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94/entry#A0A4X1UD94-1", "sequence": { "sequence": "MEPRNNVTFFILLGLTQNPKEQKVLFFIFLLFYILTVVGNLLIVVTITVSKTLNSPMYFFLASLSFIDLIYSSSITPRLILDLLFRDNTISFESCMTQLFTEHFFAGSEISLLLVMAYDRYVAICKPLHYLVIMRQRVCVVLLVLSCIGGFLHSIIQLSTIYGLPFCGPNVIDHFICDMFPLLKLVCTDTYVTGILVVANGGLMCIILFLLLLISYGVILHSLKNLSQAGRQKAIQTCGSHITVVVCFFVPCIFINARPAKTFPIDKSLSIFYTVISPMLNPLIYSLRNSELTNAMKKLWRKSYYIKW", "length": 308, "header": "tr|A0A4X1UD94-1|A0A4X1UD94_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258434 PE=3 SV=1 CANONICAL=A0A4X1UD94-1" }, "locus": { "chromosome": "AEMK02000677.1", "start_pos": 1257811, "end_pos": 1256888, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062933.1", "url": "https://www.ensembl.org/id/ENSSSCT00000062933.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041945.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041945.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UD94", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110258434", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258434", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UD94", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UD94", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UD94", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UD94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UD94" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UDL5-1", "uniprot_ac": "A0A4X1UDL5", "uniprot_id": "A0A4X1UDL5_PIG", "mass": { "chemical_mass": 11874.0, "monoisotopic_mass": 11874.0 }, "refseq": {}, "gene_names": [ { "name": "NUTF2", "type": "recommended", "evidence": [ { "id": "A0A4X1UDL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ] } ], "protein_names": [ { "name": "Nuclear transport factor 2", "type": "synonym", "evidence": [ { "id": "A0A4X1UDL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5#function" }, { "database": "UniProtKB", "id": "RU369002", "url": "https://www.uniprot.org/uniprotkb/RU369002#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NUTF2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5", "locus": { "chromosome": "6", "start_pos": 28489005, "end_pos": 28469505, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000030295", "url": "https://www.ensembl.org/id/ENSSSCG00000030295" } ] } } ], "crossref": [ { "id": "A0A4X1UDL5", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UDL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00780", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00780", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12612", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12612", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02136", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02136", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UDL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNFG", "length": 103, "header": "tr|A0A4X1UDL5-1|A0A4X1UDL5_PIG Isoform 1 of Nuclear transport factor 2 OS=Sus scrofa OX=9823 GN=NUTF2 PE=1 SV=1 CANONICAL=A0A4X1UDL5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UDL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5/entry#A0A4X1UDL5-1", "sequence": { "sequence": "MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNFG", "length": 103, "header": "tr|A0A4X1UDL5-1|A0A4X1UDL5_PIG Isoform 1 of Nuclear transport factor 2 OS=Sus scrofa OX=9823 GN=NUTF2 PE=1 SV=1 CANONICAL=A0A4X1UDL5-1" }, "locus": { "chromosome": "6", "start_pos": 28487355, "end_pos": 28482935, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048914.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048914.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037241.1", "url": "https://www.ensembl.org/id/ENSSSCP00000037241.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ], "pmid": "" }, { "name": "nuclear pore central transport channel", "id": "GO:0044613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044613", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ], "pmid": "" }, { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ], "pmid": "" }, { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDL5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UDL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDL5" }, { "id": "PS50177", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NTF2", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 29, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UDX4-1", "uniprot_ac": "A0A4X1UDX4", "uniprot_id": "A0A4X1UDX4_PIG", "mass": { "chemical_mass": 13938.0, "monoisotopic_mass": 13938.0 }, "refseq": {}, "gene_names": [ { "name": "H2BC26", "type": "recommended", "evidence": [ { "id": "A0A4X1UDX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ] } ], "protein_names": [ { "name": "Histone H2B", "type": "recommended", "evidence": [ { "id": "A0A4X1UDX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "H2BC26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4", "locus": { "chromosome": "2", "start_pos": 51687842, "end_pos": 51694212, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000061158", "url": "https://www.ensembl.org/id/ENSSSCG00000061158" } ] } } ], "crossref": [ { "id": "A0A4X1UDX4", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UDX4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22910", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22910", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000558", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LPGELAX", "url": "https://omabrowser.org/oma/group/LPGELAX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00125", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-110330", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110330", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-110331", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110331", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-171306", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-171306", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-201722", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-212300", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2299718", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2299718", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2559580", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559580", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2559582", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559582", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2559586", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559586", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3214847", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214847", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-427359", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-427359", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5250924", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5250924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5578749", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5578749", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5625886", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5625886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5693565", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693565", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5693571", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693571", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5693607", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693607", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-606279", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-606279", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68616", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-69473", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69473", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73728", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73728", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73772", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73772", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8936459", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8936459", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9018519", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018519", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9670095", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9670095", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9764725", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9764725", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9843940", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9843940", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9843970", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9843970", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9909649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9909649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9940951", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9940951", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9943962", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943962", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9970672", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970672", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UDX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPDPSKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 126, "header": "tr|A0A4X1UDX4-1|A0A4X1UDX4_PIG Isoform 1 of Histone H2B OS=Sus scrofa OX=9823 GN=H2BC26 PE=3 SV=1 CANONICAL=A0A4X1UDX4-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UDX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4/entry#A0A4X1UDX4-1", "sequence": { "sequence": "MPDPSKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 126, "header": "tr|A0A4X1UDX4-1|A0A4X1UDX4_PIG Isoform 1 of Histone H2B OS=Sus scrofa OX=9823 GN=H2BC26 PE=3 SV=1 CANONICAL=A0A4X1UDX4-1" }, "locus": { "chromosome": "2", "start_pos": 51693516, "end_pos": 51693139, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105959.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105959.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078751.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078751.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-110330", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110330", "resource": "Reactome", "description": "Recognition and association of DNA glycosylase with site containing an affected purine" }, { "id": "R-SSC-110331", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-110331", "resource": "Reactome", "description": "Cleavage of the damaged purine" }, { "id": "R-SSC-171306", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-171306", "resource": "Reactome", "description": "Packaging Of Telomere Ends" }, { "id": "R-SSC-201722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201722", "resource": "Reactome", "description": "Formation of the beta-catenin:TCF transactivating complex" }, { "id": "R-SSC-212300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212300", "resource": "Reactome", "description": "PRC2 methylates histones and DNA" }, { "id": "R-SSC-2299718", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2299718", "resource": "Reactome", "description": "Condensation of Prophase Chromosomes" }, { "id": "R-SSC-2559580", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559580", "resource": "Reactome", "description": "Oxidative Stress Induced Senescence" }, { "id": "R-SSC-2559582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559582", "resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-SSC-2559586", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559586", "resource": "Reactome", "description": "DNA Damage/Telomere Stress Induced Senescence" }, { "id": "R-SSC-3214847", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214847", "resource": "Reactome", "description": "HATs acetylate histones" }, { "id": "R-SSC-427359", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-427359", "resource": "Reactome", "description": "SIRT1 negatively regulates rRNA expression" }, { "id": "R-SSC-5250924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5250924", "resource": "Reactome", "description": "B-WICH complex positively regulates rRNA expression" }, { "id": "R-SSC-5578749", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5578749", "resource": "Reactome", "description": "Transcriptional regulation by small RNAs" }, { "id": "R-SSC-5625886", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5625886", "resource": "Reactome", "description": "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" }, { "id": "R-SSC-5693565", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693565", "resource": "Reactome", "description": "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" }, { "id": "R-SSC-5693571", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693571", "resource": "Reactome", "description": "Nonhomologous End-Joining (NHEJ)" }, { "id": "R-SSC-5693607", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693607", "resource": "Reactome", "description": "Processing of DNA double-strand break ends" }, { "id": "R-SSC-606279", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-606279", "resource": "Reactome", "description": "Deposition of new CENPA-containing nucleosomes at the centromere" }, { "id": "R-SSC-68616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68616", "resource": "Reactome", "description": "Assembly of the ORC complex at the origin of replication" }, { "id": "R-SSC-69473", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69473", "resource": "Reactome", "description": "G2/M DNA damage checkpoint" }, { "id": "R-SSC-73728", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73728", "resource": "Reactome", "description": "RNA Polymerase I Promoter Opening" }, { "id": "R-SSC-73772", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73772", "resource": "Reactome", "description": "RNA Polymerase I Promoter Escape" }, { "id": "R-SSC-8936459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8936459", "resource": "Reactome", "description": "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" }, { "id": "R-SSC-9018519", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018519", "resource": "Reactome", "description": "Estrogen-dependent gene expression" }, { "id": "R-SSC-9670095", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9670095", "resource": "Reactome", "description": "Inhibition of DNA recombination at telomere" }, { "id": "R-SSC-9764725", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9764725", "resource": "Reactome", "description": "Negative Regulation of CDH1 Gene Transcription" }, { "id": "R-SSC-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" }, { "id": "R-SSC-9843940", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9843940", "resource": "Reactome", "description": "Regulation of endogenous retroelements by KRAB-ZFP proteins" }, { "id": "R-SSC-9843970", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9843970", "resource": "Reactome", "description": "Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex" }, { "id": "R-SSC-9909649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9909649", "resource": "Reactome", "description": "Regulation of PD-L1(CD274) transcription" }, { "id": "R-SSC-9940951", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9940951", "resource": "Reactome", "description": "Interaction of NuRD complexes with transcription factors" }, { "id": "R-SSC-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" }, { "id": "R-SSC-9943962", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943962", "resource": "Reactome", "description": "CHD6, CHD7, CHD8, CHD9 subfamily" }, { "id": "R-SSC-9970672", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970672", "resource": "Reactome", "description": "FXIIa activates plasma kallikrein-kinin system" } ], "orthologs": [ { "uniprot_canonical_ac": "E1B8G9-1", "protein_name": "Histone H2B", "gene_name": "H2BC26", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPDPSKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 126 }, "evidence": [ { "id": "A0A4X1UDX4", "url": "https://omabrowser.org/oma/group/A0A4X1UDX4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "antibacterial humoral response", "id": "GO:0019731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019731", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ], "pmid": "" }, { "name": "antimicrobial humoral immune response mediated by antimicrobial peptide", "id": "GO:0061844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061844", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ], "pmid": "" }, { "name": "innate immune response in mucosa", "id": "GO:0002227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002227", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDX4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UDX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDX4" }, { "id": "PF00125", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Core Histone H2A/H2B/H3", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 101, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UDZ1-1", "uniprot_ac": "A0A4X1UDZ1", "uniprot_id": "A0A4X1UDZ1_PIG", "mass": { "chemical_mass": 48807.0, "monoisotopic_mass": 48807.0 }, "refseq": {}, "gene_names": [ { "name": "FNTB", "type": "recommended", "evidence": [ { "id": "A0A4X1UDZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1" } ] } ], "protein_names": [ { "name": "Protein farnesyltransferase subunit beta", "type": "recommended", "evidence": [ { "id": "A0A4X1UDZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.58", "type": "synonym", "evidence": [ { "id": "A0A4X1UDZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1/entry#names_and_taxonomy" } ] }, { "name": "FTase-beta", "type": "synonym", "evidence": [ { "id": "A0A4X1UDZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7H8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H8#function" }, { "database": "UniProtKB", "id": "RU365056", "url": "https://www.uniprot.org/uniprotkb/RU365056#function" }, { "database": "UniProtKB", "id": "A0A4X1UDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1#function" }, { "database": "UniProtKB", "id": "ARBA00055850", "url": "https://www.uniprot.org/uniprotkb/ARBA00055850#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FNTB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1", "locus": { "chromosome": "7", "start_pos": 89131072, "end_pos": 89052507, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002281", "url": "https://www.ensembl.org/id/ENSSSCG00000002281" } ] } } ], "crossref": [ { "id": "A0A4X1UDZ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A4X1UDZ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002281", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002281", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02893", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02893", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WCIYWIL", "url": "https://omabrowser.org/oma/group/WCIYWIL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11774", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11774", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11774:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11774:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13345", "url": "https://www.rhea-db.org/rhea/13345", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UDZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7H8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPSSFTYYCPPSSSPVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLILQREKHFHYLKRGLRHLTDAYECLDASRPWLCYWILHSLELLDEPIPQMVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIVTPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERCLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSRWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATMHFLQKPVPGFEEHEDEATAEPATD", "length": 437, "header": "tr|A0A4X1UDZ1-1|A0A4X1UDZ1_PIG Isoform 1 of Protein farnesyltransferase subunit beta OS=Sus scrofa OX=9823 GN=FNTB PE=1 SV=1 CANONICAL=A0A4X1UDZ1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UDZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1/entry#A0A4X1UDZ1-1", "sequence": { "sequence": "MASPSSFTYYCPPSSSPVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLILQREKHFHYLKRGLRHLTDAYECLDASRPWLCYWILHSLELLDEPIPQMVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIVTPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERCLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSRWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATMHFLQKPVPGFEEHEDEATAEPATD", "length": 437, "header": "tr|A0A4X1UDZ1-1|A0A4X1UDZ1_PIG Isoform 1 of Protein farnesyltransferase subunit beta OS=Sus scrofa OX=9823 GN=FNTB PE=1 SV=1 CANONICAL=A0A4X1UDZ1-1" }, "locus": { "chromosome": "7", "start_pos": 89129720, "end_pos": 89052683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002539.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002539.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002475.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002475.3" } ] } }, { "isoform_ac": "A0A5G2R7H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1/entry#A0A5G2R7H8-1", "sequence": { "sequence": "MASPSSFTYYCPPSSSPVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLILQREKHFHYLKRGLRHLTDAYECLDASRPWLCYWILHSLELLDEPIPQMVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIVTPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERCLNLKSLLVSSSQAPDPCDVTAQTCGPWDCHHSFAGFGPGPGDPALSMSRWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATMHFLQKPVPGFEEHEDEATAEPATD", "length": 426, "header": "tr|A0A5G2R7H8-1|A0A4X1UDZ1_PIG Computationally mapped isoform of Protein farnesyltransferase subunit beta OS=Sus scrofa OX=9823 GN=FNTB PE=1 SV=1 CANONICAL=A0A4X1UDZ1-1" }, "locus": { "chromosome": "7", "start_pos": 89129720, "end_pos": 89052683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089222.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089222.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070087.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070087.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7H8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7H8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1RSD4-1", "protein_name": "Protein farnesyltransferase subunit beta", "gene_name": "FNTB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGACPHGPGPHGPGGRRRLREDGVRTHTSAEQSKVEDIVQEVFDAYKTNHHAVQFVLQREKHFHYLKRGLRQLGEAYECLDASRPWLCYWILHSLELLEEPIPQSVASDVCQFLSCCQSPQGGFGGGPGQHPHLAPTYAAVNALCIIGTEEAYNVIDRQKLLEYLHTLKQPDGSFLMHVGGEVDVRSAYCAAAVASLTNILTPALFTGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKEHLLNLRSLLHWVTGRQMHFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDTALSMSHWMFDQSALQEYILLCCQCPAGGLLDKPGKSRDFYHTCYCLSGLAIAQHFGSGDLHHELVLGIPENRLRPTHPVYNIVPEKVVKAVMHFLQQPVPSLEAAG", "length": 412 }, "evidence": [ { "id": "A0A4X1UDZ1", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HCE1-1", "protein_name": "Protein farnesyltransferase subunit beta", "gene_name": "Fntb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASSSSFSYYCPPSSSPAWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEERIQEVFSNYKFNHLVPRLILQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVASDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINRQKLLQYLYSLKQPDGSFLMHIGGEVDVRSAYCATSVASLTNIITPDLFEGTPEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLKLKNLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENALQPTHPVYNIGPDKVIQATTHFLQKPVPGFEECEDEVTSDPGTD", "length": 437 }, "evidence": [ { "id": "A0A4X1UDZ1", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P49355-1", "protein_name": "Protein farnesyltransferase subunit beta", "gene_name": "FNTB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASPSSFTYCCPPSSSPIWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQMVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDVINREKLLQYLYSLKQPDGSFLMHDGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSRWMFHQQALQEYILMCCQCPTGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATMHFLQKPVPGFEEHEDEASAEPATD", "length": 437 }, "evidence": [ { "id": "A0A4X1UDZ1", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P49356-1", "protein_name": "Protein farnesyltransferase subunit beta", "gene_name": "FNTB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPSSFTYYCPPSSSPVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATTYFLQKPVPGFEELKDETSAEPATD", "length": 437 }, "evidence": [ { "id": "A0A4X1UDZ1", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q02293-1", "protein_name": "Protein farnesyltransferase subunit beta", "gene_name": "Fntb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSSSFTYYCPPSSSPVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGFEECEDAVTSDPATD", "length": 437 }, "evidence": [ { "id": "A0A4X1UDZ1", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K2I1-1", "protein_name": "Protein farnesyltransferase subunit beta", "gene_name": "Fntb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSSSFTYYCPPSSSPVWSEPLYSLRPEHVRERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLILQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDMVMGVPENVLQPTHPVYNIGPEKVIQATTHFLQKPVPGFEECEDEVTSDPATD", "length": 437 }, "evidence": [ { "id": "A0A4X1UDZ1", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VEV7-1", "protein_name": "Protein farnesyltransferase subunit beta", "gene_name": "Fntb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGTEEELMFRNFQRLKSYIFDDEKVSTTTSREQQKTESSVEKCFDRFEQIMFTDPRLTQIFRLEHQYYLDAMLRRLPSNYECLDSSRAWCVYWILQAAQLLSFNFDDQTLNHVVQFLSNCRSPTGGFGGGPGQYAHLAPTYAAVNSLCIIGSEQAYRAIDRPTLVQFLFSVRDSDGSFRLHVDGETDVRGAYCAISCAKLLNLPEPVIKELFAGTGDWIAQCQTYEGGFGGAPGLEAHGGYTFCGIAGLALLNEADKCDRQALLKWTLRRQMTYEGGFQGRTNKLVDGCYSFWVGATIPITQATLSGVDKQMEHTLFDVEALQEYILLCCQKQSGGLIDKPGKPQDLYHTCYTLSGVSIAQHSECASSPQVLGDTINELLPTHPLFNIPPKSVAAARSHFSNSNDTEFLGKDSPSKEES", "length": 419 }, "evidence": [ { "id": "A0A4X1UDZ1", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein farnesyltransferase activity", "id": "GO:0004660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004660", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1" } ], "pmid": "" }, { "name": "acetyltransferase activator activity", "id": "GO:0010698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010698", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "protein farnesyltransferase complex", "id": "GO:0005965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005965", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1" } ], "pmid": "" }, { "name": "microtubule associated complex", "id": "GO:0005875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005875", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1" } ], "pmid": "" }, { "name": "regulation of microtubule-based movement", "id": "GO:0060632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060632", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1" } ], "pmid": "" }, { "name": "prenylation", "id": "GO:0097354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097354", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13345", "name": "", "equation": "L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13345", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13345" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UDZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ1" }, { "id": "PF00432", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00432" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Prenyltransferase alpha-alpha toroid", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 403, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UDZ5-1", "uniprot_ac": "A0A4X1UDZ5", "uniprot_id": "A0A4X1UDZ5_PIG", "mass": { "chemical_mass": 40473.0, "monoisotopic_mass": 40473.0 }, "refseq": { "ac": "XP_003353636", "name": "tropomodulin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353636" }, "gene_names": [ { "name": "TMOD1", "type": "recommended", "evidence": [ { "id": "A0A4X1UDZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ] }, { "name": "TMOD1", "type": "synonym", "evidence": [ { "id": "XP_003353636", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353636" } ] } ], "protein_names": [ { "name": "Tropomodulin 1", "type": "synonym", "evidence": [ { "id": "A0A4X1UDZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5/entry#names_and_taxonomy" } ] }, { "name": "tropomodulin-1", "type": "synonym", "evidence": [ { "id": "XP_003353636", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353636" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMOD1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5", "locus": { "chromosome": "1", "start_pos": 239467758, "end_pos": 239396097, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000063066", "url": "https://www.ensembl.org/id/ENSSSCG00000063066" } ] } } ], "crossref": [ { "id": "100316850", "url": "https://www.ncbi.nlm.nih.gov/gene/100316850", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8IAH", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8IAH&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8IAI", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8IAI&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR004934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100316850", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100316850", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PYQRDKL", "url": "https://omabrowser.org/oma/group/PYQRDKL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UDZ5", "url": "https://www.orthodb.org/?gene=A0A4X1UDZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10901", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10901", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10901:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10901:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008iah", "url": "https://www.rcsb.org/structure/pdb_00008iah", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008iai", "url": "https://www.rcsb.org/structure/pdb_00008iai", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8IAH", "url": "https://www.rcsb.org/structure/8IAH", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8IAI", "url": "https://www.rcsb.org/structure/8IAI", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF03250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-390522", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-390522", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003353636", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353636", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UDZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1C6U7", "url": "https://www.uniprot.org/uniprotkb/A0A8D1C6U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1C6U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1C6U7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPMDPVLETVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKEGLNSVIKPTQYKPVPDEEPNATDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILRLVEALPYNTSLVELKIDNQSQPLGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGI", "length": 359, "header": "tr|A0A4X1UDZ5-1|A0A4X1UDZ5_PIG Isoform 1 of Tropomodulin 1 OS=Sus scrofa OX=9823 GN=TMOD1 PE=1 SV=1 CANONICAL=A0A4X1UDZ5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UDZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5/entry#A0A4X1UDZ5-1", "sequence": { "sequence": "MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPMDPVLETVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKEGLNSVIKPTQYKPVPDEEPNATDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILRLVEALPYNTSLVELKIDNQSQPLGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGI", "length": 359, "header": "tr|A0A4X1UDZ5-1|A0A4X1UDZ5_PIG Isoform 1 of Tropomodulin 1 OS=Sus scrofa OX=9823 GN=TMOD1 PE=1 SV=1 CANONICAL=A0A4X1UDZ5-1" }, "locus": { "chromosome": "1", "start_pos": 239466204, "end_pos": 239396128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037726.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037726.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054194.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054194.1" } ] } }, { "isoform_ac": "A0A8D1C6U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5/entry#A0A8D1C6U7-1", "sequence": { "sequence": "MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPMDPVLETVTLEPELEEALANASDAELCDIAGVIKPTQYKPVPDEEPNATDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILRLVEALPYNTSLVELKIDNQSQPLGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGI", "length": 329, "header": "tr|A0A8D1C6U7-1|A0A4X1UDZ5_PIG Computationally mapped isoform of Tropomodulin 1 OS=Sus scrofa OX=9823 GN=TMOD1 PE=1 SV=1 CANONICAL=A0A4X1UDZ5-1" }, "locus": { "chromosome": "1", "start_pos": 239466204, "end_pos": 239396128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044755.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044755.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056172.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056172.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Structural basis of membrane skeleton organization in red blood cells.", "journal": "Cell", "date": "2023", "authors": "Li Ningning, Chen Siyi, Xu Kui, He Meng-Ting, Dong Meng-Qiu, Zhang Qiangfeng Cliff, Gao Ning", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "reference": [ { "type": "PubMed", "id": "37044097", "url": "https://glygen.org/publication/PubMed/37044097" } ] } ], "pathway": [ { "id": "ssc:100316850", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100316850", "resource": "KEGG Pathway" }, { "id": "R-SSC-390522", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-390522", "resource": "Reactome", "description": "Striated Muscle Contraction" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4K6N4-1", "protein_name": "Tropomodulin, isoform N", "gene_name": "tmod", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDIEDVFGGSAEETKPEPDAQSKTSVVTEHTEEVIPGETEKMVTETIDEDGDVVEETTEVTRKTVKRTMKITETSATTKTTTLTTPAKLYGKDLSEYDDVDVESLLAQLSPEEITILAKEVDPDDNFLPPDQRNSYECTKEATGPLNRKQLIEHINKQAIETPDQPEFEPFVQGKVRGKKWVPPPRDARDIEAEEQIAIDMGEEYEHALNDATQEEIIDLAAILGFHSMMNQDQYHASLLNKGQPVGLGWDGITKSTQQKLFPMDPPNNTDVEESIKRVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAAAIEKSKTLRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDLVEKNSSLLRLGLHLEFNDARHRVAAHLQRNIDRIFRVQKLKPNLPKLILPGNMEIERDLVAYNRSATPSPSPSPQPPVDYEVEEDPDNMVIRGGGDAFDPDVDPDNMVVPGSRSVTPNYDDEGVYQAHTWTSASHGPSDQELHRWRLAVGFIRLGLGSLHILHRKKSIAYQ", "length": 567 }, "evidence": [ { "id": "A0A4X1UDZ5", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A3L7I324-1", "protein_name": "Tropomodulin-1", "gene_name": "Tmod1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKIWVPKQKPMDPVLESVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKEGLNSVIKPTQYKPVPDEEPNSTDVEETLERIKNNDPELEEVNLNNIRNIPIPTLKAYAEALKENSHVKKFSIVGTRSNDPVAFALAEMLKVNKVLKALNVESNFISGAGILRLVEALPHNTSLVELKIDNQSQPLGNKVEMEIVNMLEKNTTLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGV", "length": 359 }, "evidence": [ { "id": "A0A4X1UDZ5", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0JNC0-1", "protein_name": "Tropomodulin-1", "gene_name": "TMOD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSYRRELEKYRDLDEDEILGGLTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFRREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPMDPVLESVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKEGLNSVIKPTQYKPVPDEEPNATDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILRLVEALPYNTSLVELKIDNQSQPLGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGV", "length": 359 }, "evidence": [ { "id": "A0A4X1UDZ5", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9QGR6-1", "protein_name": "Tropomodulin-1 isoform X2", "gene_name": "tmod1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKEMEKYRDVDEDELLQKLSEEELRRLEDELEELDPDNALLPAGYRQRDQTKKAPTGTFQRDNLLAHLEKQAKEHPDRDDLVPYTGEKRGKPWVPKSKVVDPLLEDVTLEPELEEALSSATDAELCDIAAILGMHTLMSNQQYYEALASSTIVNKQGLNSVIQCTQYKPVPDEEPNDTDVEETLQRVKSNDPDLTEVNLNNIKNIPVPTLKAYAEALKGNSVVERLSIVGTRSNDPVAFALAEMLKVNTTLKSLNVESNFITGAGVLALVEALKSNTTLQELKIDNQSQPLGNKVEMEIANILEKNTTLLKFGYHFTQQGPRLRGSNAMMNNNDMVRKRRLEGGPIFPKCRTNV", "length": 356 }, "evidence": [ { "id": "A0A4X1UDZ5", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P49813-1", "protein_name": "Tropomodulin-1", "gene_name": "Tmod1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPMDPVLESVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKEGLNSVIKPTQYKPVPDEEPNSTDVEETLERIKNNDPELEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILRLVEALPHNTSLVELKIDNQSQPLGNKVEMEIVNMLEKNTTLLKFGYHFTQQGPRLRASNAMMSNNDLVRKRRLADLTGPIIPKCRSGV", "length": 359 }, "evidence": [ { "id": "A0A4X1UDZ5", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P70567-1", "protein_name": "Tropomodulin-1", "gene_name": "Tmod1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKIWVPKQKPMDPVLESVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKEGLNSVIKPTQYKPVPDEEPNPTDVEETLERIKNNDPELEEVNLNNIRNIPIPTLKAYAESLKENSYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILCLVEALPHNTSLVELKIDNQSQPLGNKVEMEIVNMLEKNTTLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGV", "length": 359 }, "evidence": [ { "id": "A0A4X1UDZ5", "url": "https://omabrowser.org/oma/group/A0A4X1UDZ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" }, { "name": "tropomyosin binding", "id": "GO:0005523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005523", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" }, { "name": "striated muscle thin filament", "id": "GO:0005865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005865", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" }, { "name": "cortical cytoskeleton", "id": "GO:0030863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030863", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" }, { "name": "myofibril", "id": "GO:0030016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030016", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" }, { "name": "COP9 signalosome", "id": "GO:0008180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008180", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "muscle contraction", "id": "GO:0006936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006936", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" }, { "name": "pointed-end actin filament capping", "id": "GO:0051694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051694", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" }, { "name": "lens fiber cell development", "id": "GO:0070307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070307", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" }, { "name": "myofibril assembly", "id": "GO:0030239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030239", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "8iai", "pdb_chain": "y", "start_pos": 1, "end_pos": 359, "overlap": "1.0", "method": "Electron_Microscopy", "type": "experimental", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/8iai.pdb", "url_external": "https://www.rcsb.org/structure/8iai" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 289, "end_pos": 291 }, { "start_pos": 309, "end_pos": 311 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A4X1UGW7-1", "uniprot_ac": "A0A4X1UGW7", "uniprot_id": "A0A4X1UGW7_PIG", "mass": { "chemical_mass": 51096.0, "monoisotopic_mass": 51096.0 }, "refseq": { "ac": "XP_001928268", "name": "B-cell linker protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928268" }, "gene_names": [ { "name": "BLNK", "type": "recommended", "evidence": [ { "id": "A0A4X1UGW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ] }, { "name": "BLNK", "type": "synonym", "evidence": [ { "id": "XP_001928268", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928268" } ] } ], "protein_names": [ { "name": "B cell linker", "type": "synonym", "evidence": [ { "id": "A0A4X1UGW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7/entry#names_and_taxonomy" } ] }, { "name": "B-cell linker protein", "type": "synonym", "evidence": [ { "id": "XP_001928268", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928268" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BLNK", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7", "locus": { "chromosome": "14", "start_pos": 107625803, "end_pos": 107715364, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010504", "url": "https://www.ensembl.org/id/ENSSSCG00000010504" } ] } } ], "crossref": [ { "id": "cd09929", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09929", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152350", "url": "https://www.ncbi.nlm.nih.gov/gene/100152350", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152350", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152350", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ELLEDEX", "url": "https://omabrowser.org/oma/group/ELLEDEX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1UGW7", "url": "https://www.orthodb.org/?gene=A0A4X1UGW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14098", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14098", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14098:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14098:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-983695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001928268", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928268", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1UEH6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UEH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UEH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UEH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UGW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKIVHDMKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVLPAEEAGDDSYEPPPAEQETRTVHPALPFTRGEYVDNRSSQRQSPPFSKTLPSKPSWPSAKARLVALPAAATLPAPTSLPKPQVPPKPKDLLEDEADYVVPVEDEDENYIHPTEDSSPPSEKAPMVNRSTKPNNSSKPASPPGTASGRSSGAWDSKSTSSPAAPSPLPRAGKKPAMQLKTTPVASQQNASSVCEERPIPAERHRGSSHRQENMQSPVFPPAQKPIHQKPIPLPRFPEGGSPTVDGPLPSFPSNSNLSEQEADVHCKPWYAGACDRKSAEEALYKSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIKNHQHSPLVLIDSQNNTKDSTRLKYAVKVS", "length": 463, "header": "tr|A0A4X1UGW7-1|A0A4X1UGW7_PIG Isoform 1 of B cell linker OS=Sus scrofa OX=9823 GN=BLNK PE=4 SV=1 CANONICAL=A0A4X1UGW7-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UEH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7/entry#A0A4X1UEH6-1", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKIVHDMKNNEGGIMNKIKKLKVKAPPSVPRRDYASDTCSLTNPPTPSK", "length": 67, "header": "tr|A0A4X1UEH6-1|A0A4X1UEH6_PIG Computationally mapped isoform of B cell linker OS=Sus scrofa OX=9823 GN=BLNK PE=4 SV=1 CANONICAL=A0A4X1UGW7-1" }, "locus": { "chromosome": "14", "start_pos": 107715193, "end_pos": 107680914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079366.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079366.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062717.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062717.1" } ] } }, { "isoform_ac": "A0A4X1UGW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7/entry#A0A4X1UGW7-1", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKIVHDMKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVLPAEEAGDDSYEPPPAEQETRTVHPALPFTRGEYVDNRSSQRQSPPFSKTLPSKPSWPSAKARLVALPAAATLPAPTSLPKPQVPPKPKDLLEDEADYVVPVEDEDENYIHPTEDSSPPSEKAPMVNRSTKPNNSSKPASPPGTASGRSSGAWDSKSTSSPAAPSPLPRAGKKPAMQLKTTPVASQQNASSVCEERPIPAERHRGSSHRQENMQSPVFPPAQKPIHQKPIPLPRFPEGGSPTVDGPLPSFPSNSNLSEQEADVHCKPWYAGACDRKSAEEALYKSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIKNHQHSPLVLIDSQNNTKDSTRLKYAVKVS", "length": 463, "header": "tr|A0A4X1UGW7-1|A0A4X1UGW7_PIG Isoform 1 of B cell linker OS=Sus scrofa OX=9823 GN=BLNK PE=4 SV=1 CANONICAL=A0A4X1UGW7-1" }, "locus": { "chromosome": "14", "start_pos": 107715193, "end_pos": 107630761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075374.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075374.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063770.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063770.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152350", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152350", "resource": "KEGG Pathway" }, { "id": "R-SSC-983695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983695", "resource": "Reactome", "description": "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MDI4-1", "protein_name": "B cell linker", "gene_name": "BLNK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYAPESPADEEEQWSDDFDSDYENPDEHSDSEMYVLPAEEAGDDSYEPPPVEQETRTVHPALPFTRGEYVDNRSSQRQSPPFSKTLPSKPNWPSAKARLATSLPANTSLHKPQVPPKPKELLEDEADYVVPVEDEDENYIHPTEDSSVPSEKAPMVNRSIKPNNSSKSASPPGTAPGRKSGAWDSKSTSLPAAPSPLPRAGKKTAMPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQENMQSPVFPPPAQKAVHQKPIPLPRFPEGGSPTVDGPLPSFSSNSSLSEQEADVHCKPWYAGACDRKSAEEALYRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKTGEEYFGSVAEMIKNHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 459 }, "evidence": [ { "id": "A0A4X1UGW7", "url": "https://omabrowser.org/oma/group/A0A4X1UGW7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3GZU4-1", "protein_name": "B-cell linker protein isoform X1", "gene_name": "Blnk", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMDKIKKLKVKGPPSVPRRDYALDSPADEEERWSDDFDSDYENPDEHSDSEMYVMPAEETGDDSYEPPPAEQQTRVVHPALPFTRGEYVDNRSSQRHSPPFSKTLPSKPCWPSAKTRMTSTLPAPTCLQKPQIPPKPKDLLEDEADYVVPVEDHDENYIHPRESIPLPAEKAPMVNRSTKPNSCSKPMSPPGTVTGRNSGVWDSKSSLPAAPSPLPRAGKKTATPLKTTPVTSLPNASNVCEEKPVPAERHRGSSHRQDTVQSPVFPPTQKPIHQKPVPLPRFPEGGSPAVDGPLCSLSSNSTFADQEAELHGKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVAFFNKRVYNIPVRFIEATKQYALGKKKNGEEYFGSVVDIIQNHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 457 }, "evidence": [ { "id": "A0A4X1UGW7", "url": "https://omabrowser.org/oma/group/A0A4X1UGW7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4KM52-1", "protein_name": "B-cell linker protein", "gene_name": "Blnk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMDKIKKLKVKGPPSVPRRDYALDNPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEETGDDSYEPPPAEQQTRVVHPALPFTRGEYVDNRSSQRHSPPFSKTLPSKPSWPSAKARLASTLPAPNSLQKPQVPPKPKDLLEDEADYVVPVEDNDENYIHPRESSPLPAEKAPTVNRSTKPNSSSKHVSPPGTVAGRNSGVWDSKSSLPAAPSPLPRAGKKTATPLKTTPVPSLQNASNVCEEKPVPAERHRGSSHRQDTVQSPVFPPTQKPVLQKPVPLPRFTEGGSPAADGPVPSFPFNSTFADQEAELHGKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVAFFNKRVYNIPVRFIEATKQYALGKKKNGEEYFGSVVEIIKNHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 457 }, "evidence": [ { "id": "A0A4X1UGW7", "url": "https://omabrowser.org/oma/group/A0A4X1UGW7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS", "length": 456 }, "evidence": [ { "id": "A0A4X1UGW7", "url": "https://omabrowser.org/oma/group/A0A4X1UGW7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUN3-1", "protein_name": "B-cell linker protein", "gene_name": "Blnk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMDKIKKLKVKGPPSVPRRDYALDSPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEETGDDSYEPPPAEQQTRVVHPALPFTRGEYVDNRSSQRHSPPFSKTLPSKPSWPSAKARLASTLPAPNSLQKPQVPPKPKDLLEDEADYVVPVEDNDENYIHPRESSPPPAEKAPMVNRSTKPNSSSKHMSPPGTVAGRNSGVWDSKSSLPAAPSPLPRAGKKPATPLKTTPVPPLPNASNVCEEKPVPAERHRGSSHRQDTVQSPVFPPTQKPVHQKPVPLPRFPEAGSPAADGPFHSFPFNSTFADQEAELLGKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVAFFNKRVYNIPVRFIEATKQYALGKKKNGEEYFGSVVEIVNSHQHNPLVLIDSQNNTKDSTRLKYAVKVS", "length": 457 }, "evidence": [ { "id": "A0A4X1UGW7", "url": "https://omabrowser.org/oma/group/A0A4X1UGW7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" }, { "name": "phospholipase binding", "id": "GO:0043274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043274", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" }, { "name": "protein tyrosine kinase binding", "id": "GO:1990782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990782", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1UGW7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A4X1UGW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UGW7" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 353, "end_pos": 460, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 218, "end_pos": 220 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 448, "end_pos": 450 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] } ]